Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 70.7;Proximal tubular cells: 91.0;Urothelial cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 38.7;ASC TERT1: 31.3;RPTEC TERT1: 27.1;TIME: 29.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 22000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 41.5 14.3 6.2 6.1 6.0 4.1 31.3 5.0 8.0 29.6 8.0 30.9 4.5 28.1 3.3 30.6 29.2 4.4 77.0 6.2 5.3 51.3 4.3 26.0 6.8 7.8 5.8 7.8 6.2 1.2 16.7 9.1 5.6 35.1 1.7 0.3 36.1 21.3 19.4 20.8 18.2 6.9 6.0 16.2 26.6 6.2 7.1 1.6 25.1 6.3 5.1 38.1 38.2 6.0 1.2 13.6 0.0 0.0 38.7 31.3 20.1 5.5 5.8 1.2 2.1 4.3 2.2 13.6 9.4 9.7 6.7 1.3 12.9 6.5 0.2 0.0 2.7 0.3 21.1 0.5 11.5 0.0 0.9 18.6 1.8 5.5 0.9 1.8 4.7 0.0 0.1 0.0 5.1 19.0 0.0 0.0 1.6 0.9 3.3 0.0 3.0 1.4 27.1 23.4 0.2 0.0 16.9 0.3 0.0 2.4 10.6 1.6 29.3 0.0 2.6 24.3 7.3 2.8 13.1 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 6.2 6.0 5.0 8.0 6.2 5.3 7.8 5.8 5.6 6.0 7.1 6.0 47.1 0.0 0.5 0.3 1.6 9.2 28.9 70.7 0.0 0.1 4.2 1.5 15.8 1.5 41.2 18.4 0.0 48.7 0.4 0.2 13.7 23.1 0.7 11.1 10.3 43.7 0.0 10.7 0.1 1.1 35.3 43.8 2.6 17.4 1.3 0.2 30.7 0.2 5.3 0.0 0.1 0.0 14.2 1.0 11.8 4.4 46.3 4.0 7.2 7.5 30.0 0.8 0.0 0.5 0.0 3.6 0.0 30.1 0.1 40.1 0.0 91.0 12.1 0.6 39.5 7.6 29.3 0.6 0.6 1.2 8.8 9.4 1.5 19.9 0.1 74.7 AADACL3 ENSG00000188984 "Arylacetamide deacetylase like 3" Q5VUY0 1 12716110-12728760 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "placenta: 1.6;skin 1: 1.2" "Cell type enhanced" "Detected in single" "Extravillous trophoblasts: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.01e-1)" "unprognostic (2.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AAGAB "FLJ11506, p34" ENSG00000103591 "Alpha and gamma adaptin binding protein" Q6PD74 15 67200667-67255195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039371, HPA040174" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Cytosol" "HPA039371: AB_10805476, HPA040174: AB_10805605" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (8.25e-2)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (2.84e-2)" "unprognostic (4.52e-2)" "unprognostic (9.10e-2)" "unprognostic (5.28e-2)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.88e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (1.53e-1)" 15.1 19.1 10.5 19.2 13.3 19.8 22.5 7.2 14.5 17.9 12.7 27.8 15.8 14.8 25.9 20.5 16.5 18.5 15.8 12.9 15.7 27.4 18.1 15.6 19.9 9.8 11.5 8.0 17.0 35.2 19.0 15.8 11.5 18.8 33.8 22.1 15.4 20.5 32.8 12.9 19.5 21.2 9.5 15.4 23.9 21.9 15.7 29.9 33.0 23.0 25.9 27.5 13.2 12.2 49.7 89.9 63.2 64.8 60.0 49.3 31.1 51.4 74.7 60.6 68.7 66.8 52.9 48.1 51.1 52.9 74.4 98.2 129.9 59.4 62.9 65.0 62.0 46.2 63.2 26.8 66.0 78.8 51.2 48.6 80.6 45.8 94.3 41.0 47.8 59.7 96.5 63.7 60.2 61.3 47.6 32.7 53.1 61.7 31.5 53.1 81.1 57.7 55.9 116.1 89.7 57.3 60.7 44.0 75.7 54.7 71.5 59.2 51.7 54.2 64.5 50.0 73.0 33.7 119.3 69.2 52.7 71.8 55.4 56.4 27.0 28.2 31.3 35.4 36.2 22.0 28.2 29.7 33.2 17.3 23.7 25.0 14.6 42.7 38.1 25.4 37.3 30.2 10.5 13.3 7.2 14.5 12.9 15.7 9.8 11.5 11.5 9.5 15.7 12.2 10.8 3.2 7.7 26.1 19.0 12.0 18.8 19.4 15.9 13.4 17.8 10.3 12.9 4.3 19.0 27.6 27.1 16.3 8.8 33.4 17.6 28.6 14.6 14.5 11.6 12.0 15.7 10.9 45.4 31.2 14.8 14.1 22.4 18.0 10.8 8.2 8.2 12.7 17.0 18.5 33.1 17.3 14.2 15.5 8.4 8.6 7.8 11.6 7.2 30.0 21.3 14.4 16.5 26.2 31.9 25.3 20.9 11.3 15.5 22.9 15.3 19.1 20.5 19.4 13.1 10.5 10.2 43.0 33.8 17.6 13.8 16.6 17.8 25.3 15.7 24.5 ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Hepatocytes: 175.5;Kupffer cells: 169.1;Langerhans cells: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HSkMC: 34.1;U-87 MG: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057283, CAB069889" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Vesicles" "CAB069889: AB_10002789, HPA057283: AB_2683396" "unprognostic (1.58e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (2.80e-1)" "unprognostic (7.47e-3)" "unprognostic (1.85e-1)" "unprognostic (9.22e-2)" "unprognostic (9.80e-2)" "unprognostic (2.04e-1)" "unprognostic (7.28e-3)" "unprognostic (2.14e-1)" "unprognostic (4.78e-2)" "unprognostic (1.04e-2)" "unprognostic (2.00e-3)" "unprognostic (2.51e-2)" "unprognostic (6.71e-2)" "unprognostic (2.57e-1)" 24.7 36.5 12.0 11.0 29.1 20.7 13.3 14.4 12.5 7.4 4.1 16.3 4.5 5.6 8.2 4.9 8.0 15.0 4.6 10.4 13.7 7.2 38.7 12.3 8.9 19.5 26.2 8.9 4.0 1.8 2.5 22.7 19.0 4.1 9.9 3.7 5.7 5.0 10.9 13.4 8.1 7.6 16.4 7.1 6.7 3.6 27.3 11.0 5.1 3.4 5.4 19.7 7.6 20.7 0.0 5.6 4.6 0.0 13.1 4.9 4.1 5.9 22.6 1.9 2.1 0.8 0.8 8.2 6.4 5.9 21.7 0.0 2.5 0.3 1.7 0.0 0.0 0.9 1.9 20.3 23.5 0.0 13.8 34.1 1.5 22.7 0.4 21.6 2.2 0.7 0.0 20.2 0.5 0.8 5.2 11.1 6.5 1.2 1.7 0.1 0.0 0.4 3.7 3.9 0.7 0.2 6.2 1.0 1.2 8.7 0.1 4.1 2.1 6.0 0.4 8.0 6.5 7.9 4.0 4.8 79.0 0.0 0.1 2.4 0.8 13.1 0.1 1.0 0.2 1.2 0.3 0.0 0.2 1.5 0.6 0.0 10.6 0.1 1.7 0.1 0.1 0.2 12.0 29.1 14.4 12.5 10.4 13.7 19.5 26.2 19.0 16.4 27.3 20.7 35.8 105.8 9.3 71.5 21.1 29.7 5.9 6.3 61.5 18.4 4.6 7.0 8.9 22.8 11.7 11.0 47.9 31.1 2.4 8.4 0.0 4.5 1.9 17.1 76.0 18.7 9.1 1.3 8.1 1.5 6.9 44.0 14.3 29.4 46.9 3.6 31.4 175.5 75.0 0.0 22.5 2.2 8.2 169.1 109.5 2.5 31.1 74.8 26.6 38.4 6.4 0.5 0.0 57.8 7.7 4.9 5.0 28.2 2.2 2.6 0.1 18.0 8.4 6.7 46.0 24.3 23.4 1.0 1.8 17.1 19.5 8.9 6.5 39.5 3.2 13.3 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" 10.4 11.6 0.3 4.0 0.2 3.6 8.6 0.3 0.7 10.4 4.1 16.1 1.1 11.0 0.1 22.8 7.0 3.1 11.2 0.3 0.5 8.0 2.3 15.5 4.4 1.1 0.8 8.9 8.9 3.6 7.2 2.0 0.7 15.2 0.7 0.4 9.2 0.9 21.2 9.7 12.4 6.3 0.5 15.7 15.0 13.1 0.6 4.3 21.0 0.1 1.1 15.4 12.8 0.9 4.3 43.7 0.3 11.7 3.2 4.5 0.5 15.4 19.0 13.1 13.8 6.7 34.8 7.0 79.6 29.6 11.0 12.1 3.4 12.4 4.6 22.2 4.4 16.4 22.0 16.3 25.1 5.9 39.5 15.0 9.0 1.1 2.3 3.8 10.2 28.6 17.8 6.8 0.5 5.4 12.0 0.9 3.5 1.8 8.2 41.9 7.8 5.3 0.7 15.2 6.4 11.8 18.9 17.8 3.6 11.9 6.2 0.8 3.5 0.4 2.0 11.4 11.9 13.5 7.4 3.3 6.6 0.6 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.5 1.1 0.8 0.7 0.5 0.6 0.9 8.6 25.6 5.6 10.7 13.1 8.8 8.5 18.2 9.6 3.1 4.4 3.7 6.0 4.3 14.4 5.5 22.9 0.9 9.8 2.7 3.9 9.1 11.0 15.7 12.9 8.6 18.6 16.0 26.6 6.2 3.2 12.3 49.5 17.8 22.1 16.8 8.6 0.4 8.5 5.0 38.5 6.6 14.2 21.4 9.1 14.3 7.5 12.2 3.6 11.2 10.5 1.2 5.2 12.1 15.9 11.2 4.5 6.8 15.7 18.7 0.5 1.1 9.9 8.8 0.0 6.4 5.1 4.9 6.6 18.1 5.1 0.5 17.4 37.1 3.7 11.6 ABCD1 "adrenoleukodystrophy, ALD, ALDP, AMN" ENSG00000101986 "ATP binding cassette subfamily D member 1" P33897 X 153724856-153744755 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 19.5;Proximal enterocytes: 39.2;Syncytiotrophoblasts: 27.4" "Cancer enhanced" "Detected in all" "melanoma: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 69.7;PC-3: 50.0;SK-BR-3: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035214 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA035214: " "unprognostic (1.90e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-3)" "unprognostic (5.57e-3)" "unprognostic (8.81e-3)" "unprognostic (1.54e-1)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (6.14e-3)" "unprognostic (3.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.17e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.57e-1)" "unprognostic (4.23e-2)" 14.6 33.3 3.1 5.4 3.9 4.7 12.5 3.4 3.8 7.5 2.2 14.7 10.6 33.2 1.7 3.7 9.3 3.4 11.9 2.9 3.4 7.0 13.3 7.6 3.9 4.4 3.6 5.4 11.9 2.1 10.0 4.7 4.8 9.9 1.8 0.5 6.2 5.6 20.5 4.4 17.4 4.8 3.1 13.8 7.2 19.0 5.5 4.3 6.0 4.6 1.7 11.9 6.1 4.2 13.2 4.0 2.6 11.2 7.4 3.2 34.3 6.3 6.8 4.2 7.4 2.6 7.1 3.5 69.7 8.6 11.3 1.7 1.6 1.4 0.5 11.8 2.1 10.3 42.1 34.1 9.8 6.4 22.4 6.2 1.7 4.8 0.4 4.4 6.7 4.7 6.0 12.4 5.9 4.7 4.5 6.1 3.3 3.2 50.0 7.8 6.2 5.7 3.2 1.4 2.8 11.5 16.4 49.2 26.4 3.0 3.7 10.8 7.9 5.5 7.4 14.3 7.0 12.2 5.7 8.4 6.9 21.7 7.8 0.4 3.2 2.5 0.8 3.0 4.0 1.0 1.0 1.2 2.7 0.7 1.1 0.8 1.7 0.7 2.8 1.7 0.3 2.5 3.1 3.9 3.4 3.8 2.9 3.4 4.4 3.6 4.8 3.1 5.5 4.2 5.0 0.0 1.1 3.6 3.8 3.2 1.6 1.6 0.6 2.2 2.7 2.8 2.4 2.8 2.2 3.7 2.1 12.2 4.8 9.5 0.0 3.8 0.7 2.0 3.5 3.4 6.0 3.6 0.5 6.9 19.5 4.5 3.6 4.0 0.0 6.9 5.7 6.8 12.6 8.4 0.9 5.0 2.0 15.9 8.4 2.7 4.1 12.3 1.8 0.0 5.9 2.4 0.0 0.0 1.2 5.0 2.1 5.7 2.4 0.8 39.2 2.8 1.2 0.7 6.6 2.3 2.8 3.8 4.8 0.8 1.3 27.4 4.0 7.8 5.5 1.4 ABCD2 "ALDL1, ALDR, ALDRP" ENSG00000173208 "ATP binding cassette subfamily D member 2" Q9UBJ2 12 39550033-39619803 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.7;brain: 8.9" "Cell type enhanced" "Detected in some" "Astrocytes: 71.5;Bipolar cells: 57.2;Excitatory neurons: 33.2;Inhibitory neurons: 34.2" "Cancer enriched" "Detected in single" 7 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in single" 4 "T-cells: 4.2" "Group enriched" "Detected in some" 6 "ASC diff: 11.6;HDLM-2: 16.9;Karpas-707: 29.0;SH-SY5Y: 17.3;U-266/70: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.26e-3)" "unprognostic (4.06e-4)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (2.06e-1)" "unprognostic (7.31e-5)" "unprognostic (3.42e-2)" "unprognostic (2.90e-2)" "unprognostic (8.06e-3)" "unprognostic (3.43e-2)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-4)" "unprognostic (5.04e-2)" "unprognostic (8.04e-2)" "unprognostic (1.13e-1)" "unprognostic (6.74e-2)" 15.7 1.7 1.5 1.7 2.2 0.2 2.8 8.9 5.2 5.3 0.0 0.7 0.5 2.7 0.2 0.4 2.7 0.5 4.2 2.1 2.1 0.5 0.1 0.5 2.8 2.2 3.3 0.1 0.1 0.0 0.5 0.0 2.4 0.4 0.7 5.9 2.6 0.6 0.1 0.1 0.7 2.6 1.3 1.6 0.7 0.2 3.6 1.4 0.2 0.3 1.6 0.9 0.6 1.4 0.0 0.0 0.1 0.0 11.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 16.9 0.0 0.1 0.0 0.0 0.6 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 9.8 1.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 1.2 0.5 2.8 3.7 0.1 0.3 3.2 4.2 0.1 0.9 0.0 0.6 3.6 1.2 1.5 2.2 8.9 5.2 2.1 2.1 2.2 3.3 2.4 1.3 3.6 1.4 0.4 0.0 0.0 71.5 2.6 0.0 0.0 0.0 0.0 57.2 0.3 0.3 10.9 0.0 0.0 0.0 6.2 0.0 3.8 0.1 0.0 0.0 0.3 0.2 0.5 0.2 0.0 0.0 33.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.1 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.5 1.1 2.2 0.0 13.0 1.3 0.0 0.0 0.7 5.9 0.0 0.0 0.9 2.4 2.3 0.0 0.4 2.5 0.2 0.1 0.0 0.0 0.0 7.8 0.6 0.1 0.0 ABCD3 "PMP70, PXMP1, ZWS2" ENSG00000117528 "ATP binding cassette subfamily D member 3" P28288 1 94418389-94518666 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 126.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032026, HPA032027, CAB032516, CAB075749" Enhanced Enhanced Peroxisomes NA NA 12000 "Cluster 39: Non-specific - mRNA processing" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Peroxisomes "CAB032516: AB_2257637, CAB075749: AB_2665755, HPA032026: AB_2674117, HPA032027: AB_10602103" "unprognostic (1.41e-2)" "unprognostic (3.21e-1)" "prognostic favorable (1.16e-5)" "unprognostic (1.92e-1)" "unprognostic (5.42e-2)" "unprognostic (1.56e-1)" "unprognostic (1.94e-2)" "unprognostic (2.54e-2)" "unprognostic (5.10e-2)" "unprognostic (3.20e-2)" "unprognostic (1.01e-1)" "unprognostic (9.12e-2)" "prognostic favorable (4.84e-5)" "unprognostic (5.45e-2)" "unprognostic (6.20e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" 16.8 18.7 19.8 16.2 23.2 25.1 32.8 22.7 24.3 22.4 22.6 44.6 44.5 14.7 21.2 26.7 16.7 26.8 26.0 18.7 21.8 59.4 126.6 23.3 13.3 22.1 21.2 10.1 28.6 29.6 13.3 14.4 22.7 21.5 40.2 26.3 17.5 27.0 23.5 35.5 46.1 17.7 23.7 11.0 43.5 16.3 21.4 47.5 27.5 29.8 21.2 22.9 16.2 27.3 81.5 37.6 37.8 36.1 28.3 31.0 55.8 41.4 32.0 46.8 51.5 117.5 25.0 49.8 52.1 52.8 50.0 58.2 43.7 53.7 64.9 40.1 36.9 56.7 52.3 102.5 27.5 51.2 17.0 26.2 29.6 54.2 20.8 30.2 29.0 47.0 25.8 29.2 48.6 11.4 86.4 26.8 43.7 61.7 50.7 48.0 78.4 19.4 45.6 122.2 28.5 46.7 71.5 75.2 55.7 28.4 27.7 41.8 28.9 34.5 49.5 61.3 55.9 16.5 16.5 48.4 27.1 25.6 16.4 0.4 3.8 2.9 4.2 4.3 4.0 1.8 3.8 4.9 5.9 1.8 4.5 4.4 0.9 5.9 3.8 1.5 4.6 3.3 19.8 23.2 22.7 24.3 18.7 21.8 22.1 21.2 22.7 23.7 21.4 27.3 16.9 35.3 48.8 64.3 10.2 23.3 16.2 32.8 14.8 27.5 43.7 21.1 39.1 58.6 43.2 42.3 22.9 25.0 12.3 72.1 23.5 22.8 9.0 37.5 16.8 16.4 39.7 8.4 32.7 44.5 12.0 18.3 37.8 30.6 27.9 19.1 18.2 108.9 11.0 33.7 47.5 37.5 26.4 21.9 7.4 8.2 13.7 15.0 16.0 40.3 15.1 78.4 11.3 67.3 96.5 37.5 33.0 24.5 15.4 20.4 75.7 72.3 49.8 26.3 19.7 19.0 17.7 14.5 23.2 21.0 34.0 15.3 15.4 16.7 39.5 32.5 ABHD15 ENSG00000168792 "Abhydrolase domain containing 15" Q6UXT9 17 29560547-29567037 "Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 26.2" "Cell type enhanced" "Detected in many" "dendritic cells: 79.4;Hepatocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;MAIT T-cell: 6.6;NK-cell: 10.8;plasmacytoid DC: 23.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA014470 Approved Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA014470: AB_1852993" "unprognostic (1.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.38e-1)" "unprognostic (8.60e-3)" "unprognostic (1.91e-1)" "unprognostic (1.62e-1)" "unprognostic (4.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.85e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-3)" "unprognostic (3.00e-2)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (1.71e-1)" "unprognostic (3.46e-1)" "unprognostic (5.45e-2)" 19.2 3.8 3.6 6.2 4.0 8.2 10.6 3.8 3.3 4.6 3.8 7.3 11.2 4.5 3.3 4.7 4.7 5.2 4.9 3.1 4.1 8.9 26.2 6.0 9.1 4.9 4.2 2.9 8.1 7.9 9.1 4.5 4.7 4.7 6.5 1.6 5.1 3.8 2.6 4.6 11.2 4.0 4.2 9.9 8.3 1.8 4.3 4.6 5.8 3.8 8.1 5.6 4.6 4.9 5.8 22.1 2.7 7.7 29.0 12.6 11.3 7.8 8.6 7.6 6.9 5.1 2.9 8.6 5.6 8.4 13.4 15.6 9.7 3.3 4.2 26.5 7.3 3.5 11.0 6.5 8.8 9.0 15.4 9.4 8.9 7.3 1.4 5.6 5.6 5.0 4.6 8.0 4.1 7.8 8.5 10.4 0.6 19.5 6.5 19.7 10.5 20.0 13.7 8.8 1.9 3.1 11.7 5.2 3.1 2.9 13.2 20.5 6.9 4.4 5.5 11.1 7.0 13.3 9.6 4.4 8.8 5.6 9.6 18.3 0.6 2.8 2.6 0.3 6.6 1.4 1.4 2.2 1.5 2.5 0.4 1.3 0.6 10.8 0.2 23.6 1.2 1.1 3.6 4.0 3.8 3.3 3.1 4.1 4.9 4.2 4.7 4.2 4.3 4.9 2.4 3.2 4.1 2.6 11.7 1.3 1.1 2.5 2.2 0.1 3.8 2.4 3.0 2.8 4.3 7.3 0.0 1.5 79.4 12.0 0.0 3.0 0.3 4.7 3.1 2.9 7.2 7.0 0.3 7.6 1.4 4.0 2.0 5.1 2.5 2.9 4.2 30.2 7.2 1.7 0.5 6.1 2.0 6.7 8.4 0.7 4.7 9.5 5.4 2.8 5.6 1.1 15.5 0.5 1.2 5.6 2.5 4.5 5.2 1.5 17.7 5.6 5.2 0.9 0.0 3.5 1.9 0.8 0.6 2.0 2.4 0.3 11.8 4.5 7.4 1.2 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 67.8;neutrophil: 42.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favorable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favorable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 38.8 12.5 6.7 8.5 8.6 39.6 27.9 10.5 8.9 9.8 6.0 12.3 9.9 5.7 4.1 31.1 5.1 11.6 13.4 6.8 7.4 12.0 21.7 16.4 3.4 9.2 8.2 4.6 16.0 12.2 5.6 10.2 9.1 7.1 7.5 6.3 27.4 8.4 15.0 38.0 10.5 9.3 9.3 9.4 12.1 10.8 8.4 6.8 15.5 18.5 7.9 16.7 16.9 11.9 18.9 6.8 8.2 9.7 32.0 12.8 17.1 77.4 27.1 18.8 14.9 9.4 6.4 16.2 10.9 23.2 15.8 5.8 16.5 18.5 22.6 58.4 13.2 36.6 24.4 7.5 15.7 9.2 13.2 13.0 64.6 31.3 28.5 18.8 33.3 10.8 23.9 14.2 46.9 11.0 7.6 6.9 22.8 16.7 20.4 3.1 24.1 8.6 27.9 40.4 10.6 13.6 36.9 20.5 9.8 9.8 18.9 8.9 19.3 18.1 13.6 35.0 34.5 11.1 34.0 7.7 20.3 17.3 16.0 67.8 14.7 9.5 2.3 7.9 1.7 3.5 1.7 2.7 6.8 4.0 1.6 2.5 42.5 2.0 5.7 1.9 4.8 5.3 6.7 8.6 10.5 8.9 6.8 7.4 9.2 8.2 9.1 9.3 8.4 11.9 117.5 25.6 51.8 12.7 44.8 39.9 27.5 25.9 88.8 11.9 149.9 116.2 10.3 14.3 49.6 27.6 27.1 16.7 80.3 65.0 33.2 57.5 19.5 47.5 49.0 34.6 36.2 69.0 24.1 61.5 24.9 53.7 67.8 114.0 16.5 8.8 18.2 12.7 18.0 3.3 24.1 23.7 34.6 44.1 17.4 17.1 5.3 79.8 7.2 11.2 35.9 11.0 12.3 18.1 28.8 75.2 49.8 5.7 41.8 25.5 98.5 39.8 19.1 17.4 0.0 32.0 46.4 47.3 41.9 111.7 40.9 205.4 42.6 15.2 21.9 71.6 ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713016-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 71.2;Oligodendrocytes: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Yes No "Cluster 37: B-cells - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 50.9 30.7 27.4 25.3 38.9 23.4 45.8 33.6 31.4 60.5 40.4 96.4 23.1 63.0 11.6 33.8 55.6 35.7 36.1 26.6 28.3 23.1 17.5 37.3 16.3 39.3 38.5 56.0 24.9 32.5 34.9 26.5 35.8 43.5 26.7 14.2 32.4 33.6 29.4 36.3 45.2 41.2 31.3 23.3 51.6 20.1 34.9 22.4 46.7 30.8 15.4 79.3 42.7 41.3 22.5 48.3 53.6 62.9 76.5 93.3 18.8 38.8 60.4 44.8 38.1 36.4 28.3 32.3 22.3 52.0 47.6 42.5 23.5 36.0 30.7 20.6 16.3 23.7 84.1 33.4 51.8 36.5 32.3 68.8 37.2 80.6 50.0 64.1 61.0 47.9 135.8 26.5 54.9 42.0 49.2 30.5 57.9 34.3 33.8 55.9 67.9 35.9 45.0 25.7 47.9 60.1 66.1 23.5 29.2 31.0 46.2 33.1 71.1 170.7 44.1 66.3 62.6 8.4 20.3 47.9 72.1 27.6 55.1 0.0 0.7 0.3 0.6 0.4 0.8 1.3 0.6 0.6 0.7 0.4 0.6 0.5 0.0 0.8 1.9 1.0 0.3 0.6 27.4 38.9 33.6 31.4 26.6 28.3 39.3 38.5 35.8 31.3 34.9 41.3 16.2 9.6 13.6 54.9 4.7 9.2 7.3 9.8 5.2 8.2 11.6 10.2 6.2 7.2 7.2 14.7 12.5 13.6 12.1 21.2 1.9 14.4 5.9 8.6 29.7 18.1 22.1 4.6 52.5 11.1 4.3 36.7 5.6 12.4 2.5 22.1 20.3 15.9 16.6 10.1 63.7 17.5 6.1 16.4 11.7 8.8 28.0 10.2 5.4 71.2 6.6 19.2 6.2 66.9 116.0 17.9 18.3 25.6 5.6 8.6 11.6 10.3 7.8 9.1 19.7 29.5 19.8 16.9 16.5 6.6 6.8 15.2 7.9 20.1 21.4 7.2 ABLIM2 KIAA1808 ENSG00000163995 "Actin binding LIM protein family member 2" Q6H8Q1 4 7965310-8158832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 204.8;tongue: 73.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 93.2;Inhibitory neurons: 67.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 13.8;SiHa: 5.9;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035808 Uncertain Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria Nucleoplasm "HPA035808: AB_10601962" "unprognostic (7.57e-2)" "unprognostic (3.24e-3)" "unprognostic (7.78e-2)" "unprognostic (3.33e-1)" "unprognostic (2.86e-2)" "unprognostic (6.09e-2)" "unprognostic (1.49e-2)" "unprognostic (5.54e-2)" "unprognostic (1.46e-1)" "unprognostic (5.01e-3)" "unprognostic (2.04e-2)" "unprognostic (3.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.32e-2)" "unprognostic (5.15e-2)" "unprognostic (1.45e-1)" "unprognostic (2.45e-2)" 7.3 4.0 2.7 1.6 11.0 0.1 5.1 0.0 9.9 2.5 0.0 2.3 0.5 1.2 0.7 13.1 1.8 1.3 7.1 2.7 10.4 7.0 0.9 3.3 1.0 1.4 0.0 0.6 3.4 1.3 6.8 0.6 1.1 1.5 1.7 5.0 5.4 0.5 204.8 6.9 1.6 1.9 0.0 20.5 1.4 1.0 1.4 1.7 3.0 73.5 2.2 1.9 4.1 0.0 1.1 0.0 0.2 1.6 0.4 0.1 0.4 0.0 0.0 0.1 0.0 0.0 1.5 3.1 0.3 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.4 0.0 1.3 0.0 0.7 0.0 0.0 0.1 1.1 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.7 2.1 0.1 0.0 1.2 2.9 0.9 0.2 1.0 0.7 0.2 0.0 13.8 1.0 5.9 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.4 20.7 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.6 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 2.7 11.0 0.0 9.9 2.7 10.4 1.4 0.0 1.1 0.0 1.4 0.0 4.4 0.0 1.1 9.4 0.5 2.5 0.1 0.1 0.6 6.4 0.4 0.3 4.7 1.5 0.3 3.7 0.0 0.0 0.6 7.9 0.0 3.5 2.2 5.2 0.7 3.5 10.7 0.0 93.2 4.3 0.6 0.9 2.6 0.2 2.5 0.5 0.7 0.4 0.1 11.8 67.6 3.8 0.0 0.6 0.7 5.1 0.0 0.3 0.0 2.8 0.0 3.1 0.0 16.1 17.6 3.5 5.1 3.8 0.1 0.3 14.3 0.6 1.7 3.2 6.6 7.0 3.5 0.2 2.0 2.0 6.3 0.0 0.7 4.0 5.8 0.3 AC135068.1 ENSG00000278263 "Novel protein, identical to IGHV4-4" 15 21742364-21742799 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 52.2;lymphoid tissue: 57.9;urinary bladder: 97.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "memory B-cell: 24.0;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 45 "B-cells: 24.0" "Not detected" "Not detected" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.93e-1)" "prognostic favorable (2.52e-4)" "unprognostic (1.05e-1)" "unprognostic (9.75e-3)" "unprognostic (1.80e-2)" "unprognostic (5.51e-6)" "unprognostic (5.57e-2)" "unprognostic (3.76e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-1)" 1.0 0.0 0.2 27.3 0.1 4.2 5.4 0.0 0.0 3.7 0.0 52.2 22.6 0.2 0.0 3.7 0.5 0.5 2.1 0.1 0.0 0.2 1.0 5.5 5.5 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.4 22.1 0.0 30.1 2.1 0.0 1.1 6.0 0.0 0.0 9.4 22.3 0.1 0.0 7.8 0.7 0.0 57.9 97.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.2 0.0 0.0 7.7 0.3 0.0 0.0 0.0 0.0 0.0 0.5 1.9 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC135068.5 ENSG00000281179 "Novel gene identicle to IGHV1OR15-1" 15 21717808-21718245 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 78.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 94.3;naive B-cell: 111.6" "Group enriched" "Detected in many" 18 "B-cells: 111.6;T-cells: 60.9" "Group enriched" "Detected in some" 4 "JURKAT: 10.3;Karpas-707: 6.9;MOLT-4: 2.5" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "unprognostic (3.64e-1)" "unprognostic (8.63e-2)" 0.6 0.4 0.0 18.2 0.1 7.0 5.8 0.1 0.1 0.8 0.0 15.6 13.8 0.8 0.0 4.0 0.6 14.4 0.6 0.0 0.1 0.4 0.7 2.8 52.0 0.2 0.1 1.0 0.4 0.1 0.1 0.1 0.1 2.3 10.2 0.0 4.9 0.4 0.0 0.1 13.7 0.4 0.2 17.6 11.1 0.1 0.1 58.7 1.0 0.0 78.8 9.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 6.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 9.2 0.0 3.3 94.3 54.9 18.1 0.1 111.6 60.9 14.5 0.5 4.8 0.1 3.3 35.9 20.5 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 ACACB "ACC2, ACCB, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116595-109268226 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 183.3;skeletal muscle: 173.2" "Cell type enhanced" "Detected in many" "Adipocytes: 128.7;Astrocytes: 136.8;Hepatocytes: 216.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 17.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.5" "Cell line enriched" "Detected in many" 18 "ASC diff: 222.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA006554 Enhanced "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA006554: AB_1844495" "unprognostic (2.24e-1)" "unprognostic (4.66e-1)" "unprognostic (3.97e-2)" "unprognostic (4.54e-6)" "unprognostic (2.82e-1)" "unprognostic (1.59e-2)" "unprognostic (8.62e-3)" "unprognostic (5.81e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.63e-2)" "prognostic favorable (1.15e-5)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-3)" "unprognostic (2.58e-2)" 183.3 19.8 19.6 3.3 21.7 3.6 100.5 7.6 11.4 12.9 26.9 37.2 8.4 12.0 3.5 10.6 12.1 10.9 35.4 10.1 11.2 12.6 54.3 6.7 3.8 12.7 19.4 14.3 19.2 17.9 11.2 2.5 11.6 11.8 8.2 1.7 12.5 11.7 173.2 9.5 15.5 9.4 6.7 7.8 18.6 4.9 19.1 4.5 18.1 61.5 3.0 23.0 11.5 13.2 0.9 5.7 3.6 6.9 222.6 1.7 2.6 0.9 1.5 1.0 0.6 4.1 1.1 2.9 1.6 1.2 2.4 4.8 3.0 1.5 0.6 3.8 5.3 6.6 6.2 4.3 1.0 5.7 1.6 2.6 1.5 2.3 0.6 1.7 0.5 4.9 0.7 0.3 0.7 1.7 4.1 5.3 3.9 0.4 12.4 2.2 4.8 1.5 1.8 2.0 2.3 5.4 5.9 2.8 3.4 1.5 2.6 5.9 0.4 2.2 1.3 2.5 1.9 8.8 5.3 4.0 5.3 4.5 1.7 4.6 0.4 17.5 1.1 0.1 0.6 2.2 1.0 0.3 0.2 3.0 1.8 0.9 0.7 0.1 0.2 0.3 0.6 0.1 19.6 21.7 7.6 11.4 10.1 11.2 12.7 19.4 11.6 6.7 19.1 13.2 128.7 6.4 1.1 136.8 3.7 2.3 2.6 1.0 3.4 3.1 32.5 5.0 35.3 25.8 1.7 23.9 0.0 0.6 2.4 13.9 1.9 2.1 34.3 3.3 3.4 26.0 10.2 25.7 5.1 4.0 0.5 16.0 18.3 1.3 1.3 20.0 41.4 216.5 1.7 23.5 6.4 9.6 0.0 12.6 2.4 36.4 29.2 3.7 5.4 28.1 1.2 5.2 2.1 29.7 25.8 2.7 7.3 50.4 2.5 0.9 17.9 6.5 2.3 4.1 6.6 29.3 12.0 2.3 3.0 2.5 1.6 0.1 3.5 21.8 11.8 1.1 ACAD8 ENSG00000151498 "Acyl-CoA dehydrogenase family member 8" Q9UKU7 11 134253548-134265855 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism, Transcription, Transcription regulation" "Activator, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040689, HPA043903" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA040689: AB_2677080, HPA043903: AB_2678724" "unprognostic (5.00e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.62e-4)" "unprognostic (7.57e-3)" "unprognostic (9.83e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.53e-1)" "prognostic favorable (2.38e-4)" "unprognostic (4.10e-2)" "unprognostic (2.84e-1)" "unprognostic (7.81e-3)" "unprognostic (2.16e-1)" "prognostic favorable (6.42e-10)" "unprognostic (1.08e-1)" "unprognostic (1.17e-2)" "unprognostic (4.02e-2)" "unprognostic (1.03e-2)" 11.0 18.1 13.9 3.5 14.2 6.8 11.3 14.3 15.4 7.5 18.7 11.6 11.3 6.3 12.6 9.6 9.4 5.2 27.2 14.7 14.3 31.6 24.8 7.8 5.0 14.3 14.1 6.9 16.7 12.4 6.5 4.8 13.8 20.5 10.9 5.0 12.6 7.5 32.5 14.3 8.4 8.3 14.5 8.6 12.6 6.3 14.8 8.5 27.7 39.2 8.9 8.4 6.9 14.8 5.9 5.9 11.8 17.6 20.2 11.5 13.5 11.3 14.0 14.7 10.3 16.2 10.8 14.2 21.1 11.7 15.5 6.0 14.6 14.3 10.2 13.0 4.7 29.4 5.8 11.3 17.0 16.5 18.3 13.8 4.4 14.8 4.5 13.3 16.3 20.8 13.8 7.0 12.4 7.5 12.2 18.1 17.0 49.8 9.7 9.8 11.9 8.5 20.1 17.5 3.7 11.7 19.5 14.8 7.3 11.9 31.0 15.0 11.3 7.1 7.5 6.2 11.2 7.8 3.8 12.7 7.2 15.4 11.2 36.2 13.4 23.1 11.8 13.5 11.5 11.6 11.1 11.7 12.7 9.2 13.0 11.7 12.1 31.5 12.9 10.8 15.1 12.3 13.9 14.2 14.3 15.4 14.7 14.3 14.3 14.1 13.8 14.5 14.8 14.8 11.7 3.2 12.2 15.3 8.8 6.0 4.7 23.5 7.4 11.2 17.5 11.9 24.6 4.3 19.7 18.4 14.6 19.7 14.0 20.0 52.8 12.1 5.3 8.2 11.8 9.7 3.6 12.0 21.5 11.9 10.6 9.8 10.2 8.5 3.8 15.7 10.8 36.7 12.9 15.2 16.0 14.3 48.8 14.2 6.9 6.1 11.5 10.0 28.4 13.1 12.7 11.8 9.2 12.1 15.8 12.6 15.8 10.1 14.6 5.9 17.4 59.8 20.1 17.1 6.6 8.7 9.6 22.4 17.3 10.9 7.7 8.3 10.5 36.0 14.9 5.3 ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187126-210225447 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.0;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.9;Early spermatids: 85.6;Late spermatids: 69.4;Leydig cells: 46.9;Peritubular cells: 46.6;Proximal tubular cells: 31.5" "Group enriched" "Detected in many" 8 "liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;RPTEC TERT1: 2.6;SuSa: 2.3;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "HPA011990: AB_1844465" "unprognostic (6.29e-3)" "unprognostic (7.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (7.66e-3)" "unprognostic (3.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.99e-1)" "prognostic favorable (1.58e-11)" "unprognostic (4.22e-3)" "unprognostic (1.18e-4)" "unprognostic (8.81e-3)" "unprognostic (1.06e-1)" 11.9 1.1 0.8 0.1 0.8 0.0 8.0 0.7 1.1 3.4 0.9 0.5 0.0 0.7 1.1 0.5 4.0 0.6 3.1 0.7 1.2 19.8 28.0 10.1 0.0 0.8 0.8 12.7 28.4 4.5 2.9 1.0 0.8 20.6 0.1 0.0 6.8 4.8 9.5 2.8 0.4 0.1 0.8 0.0 5.6 3.1 0.7 1.5 23.7 5.0 0.0 1.0 3.8 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.6 0.5 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.1 0.7 1.2 0.8 0.8 0.8 0.8 0.7 0.9 0.2 28.9 70.9 1.0 0.0 0.6 1.4 1.1 1.2 0.2 1.3 0.5 1.1 8.6 7.6 22.0 2.1 8.8 0.0 0.0 15.6 4.0 85.6 7.1 0.4 0.2 0.0 0.0 0.2 11.9 0.3 4.9 3.6 5.9 2.5 0.8 0.7 23.0 0.5 0.0 13.3 0.0 0.0 0.3 0.4 69.4 46.9 0.4 0.0 4.7 0.0 0.2 0.0 7.5 0.3 3.9 0.0 46.6 0.0 8.2 0.0 31.5 2.4 0.2 0.0 7.6 13.7 0.7 0.7 0.7 1.0 6.3 0.4 0.1 0.0 0.7 ACADS "ACAD3, SCAD" ENSG00000122971 "Acyl-CoA dehydrogenase short chain" P16219 12 120725774-120740008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 245.5;skeletal muscle: 158.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 303.1;Hepatocytes: 203.3;Paneth cells: 185.7;Proximal enterocytes: 435.0;Undifferentiated cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004799, CAB019284, HPA022271" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" Mitochondria "CAB019284: , HPA004799: AB_1844471, HPA022271: AB_1844472" "unprognostic (7.14e-2)" "unprognostic (3.03e-3)" "unprognostic (8.15e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.11e-3)" "unprognostic (5.75e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (2.69e-2)" "unprognostic (4.04e-2)" "prognostic favorable (3.33e-6)" "unprognostic (1.23e-2)" "unprognostic (1.81e-1)" "unprognostic (1.21e-1)" "prognostic favorable (6.34e-5)" 50.3 52.7 13.3 11.1 15.4 14.3 40.9 13.6 16.6 11.2 13.7 74.0 84.8 10.2 0.9 14.1 10.2 8.5 90.5 12.3 13.8 51.9 245.5 13.4 6.4 14.6 14.2 8.6 33.1 4.7 9.2 7.5 13.1 13.9 21.3 0.9 19.2 7.2 158.2 13.7 73.2 5.8 14.0 31.6 34.5 20.3 16.0 6.6 21.9 79.7 3.4 18.0 12.7 14.8 3.2 11.4 0.6 9.7 12.9 5.1 11.1 4.7 4.6 6.0 4.5 8.9 8.0 0.3 11.9 3.9 2.7 5.2 6.6 2.1 0.8 16.7 8.2 8.2 3.6 19.3 9.3 0.7 36.0 15.4 3.1 2.6 0.2 1.8 6.1 20.6 6.9 0.1 2.7 6.8 11.7 19.2 2.0 10.6 4.6 8.6 4.2 2.2 11.3 18.2 1.1 6.0 9.7 0.0 15.8 0.9 7.7 13.1 6.9 0.2 4.7 4.5 0.9 15.3 9.3 4.1 10.2 7.0 4.1 8.3 15.3 7.5 13.7 16.3 9.3 6.3 12.2 14.2 13.2 8.9 15.3 14.4 1.4 19.9 10.2 11.0 14.7 12.8 13.3 15.4 13.6 16.6 12.3 13.8 14.6 14.2 13.1 14.0 16.0 14.8 18.8 12.8 13.7 10.1 6.7 6.6 9.5 21.1 4.0 1.0 25.0 14.9 44.0 27.1 13.0 18.4 0.0 78.8 9.8 303.1 50.9 35.2 23.5 12.8 8.2 13.4 45.6 38.5 2.3 32.6 31.3 18.1 28.5 10.8 19.1 12.8 19.2 203.3 55.1 1.7 2.8 105.3 20.3 21.0 8.9 36.5 21.5 15.3 17.8 0.0 26.1 13.6 18.6 3.0 3.6 26.7 185.7 18.0 7.9 8.3 435.0 94.8 7.3 0.6 6.6 13.2 12.7 41.5 8.1 9.4 4.5 75.5 11.9 140.6 185.9 12.7 ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 508.4;Distal tubular cells: 698.5;Hepatocytes: 663.4;Proximal tubular cells: 1484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 420.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 135.4 151.3 45.2 24.3 45.3 38.4 56.9 47.1 60.1 41.0 91.8 96.3 103.9 44.0 34.1 45.0 39.1 25.6 289.4 42.7 46.8 622.7 969.5 43.7 28.2 44.8 45.2 64.7 110.6 95.9 30.9 24.7 45.2 45.6 85.6 26.2 104.1 60.2 461.1 45.3 53.2 57.1 46.7 29.3 81.9 66.3 45.6 19.1 65.5 410.8 29.7 44.1 34.6 47.7 76.9 57.7 48.2 139.3 155.9 138.7 25.1 71.7 78.8 77.7 91.7 168.1 77.3 41.3 116.8 83.6 119.7 78.1 142.3 70.3 83.3 84.9 114.6 117.4 64.6 163.9 107.6 112.9 64.9 124.6 77.1 69.2 127.4 91.5 85.0 92.3 172.1 61.8 128.6 45.8 57.4 122.4 48.2 103.1 135.0 88.1 96.9 420.4 114.7 50.4 75.7 88.1 111.6 152.7 83.0 37.0 132.2 97.6 87.4 83.2 44.5 73.5 88.8 18.9 57.8 77.7 37.6 233.1 59.6 1.4 17.1 4.7 25.3 25.5 29.9 29.2 28.8 30.0 33.5 13.8 25.5 22.4 1.8 13.4 27.8 11.3 35.7 23.4 45.2 45.3 47.1 60.1 42.7 46.8 44.8 45.2 45.2 46.7 45.6 47.7 50.5 54.5 91.8 17.9 37.2 43.1 52.2 48.9 23.9 30.1 34.6 29.6 508.4 78.6 33.5 104.8 27.1 39.9 29.2 125.0 698.5 43.1 345.7 62.2 42.1 62.5 30.0 74.7 35.1 60.5 41.5 57.1 29.0 25.7 27.8 48.6 99.2 663.4 97.9 38.7 37.8 38.5 97.6 73.6 27.8 65.3 66.5 39.1 58.7 30.0 50.1 39.1 25.7 22.6 26.5 33.8 93.8 82.4 52.7 27.8 51.4 1484.0 101.8 28.8 65.7 54.2 69.2 172.7 27.2 39.2 48.4 25.2 38.1 61.6 84.5 24.4 ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409009-19452505 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "stomach 1: 61.8;urinary bladder: 39.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.7;Gastric mucus-secreting cells: 21.9;Inhibitory neurons: 10.3;Microglial cells: 26.2;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BEWO: 29.7;RT4: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.94e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (2.03e-1)" "unprognostic (3.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (8.46e-3)" 6.9 1.4 4.5 1.1 3.4 0.6 5.0 2.7 5.0 1.7 2.0 3.3 4.5 1.4 4.2 2.2 3.7 1.7 2.9 4.4 3.1 1.9 2.4 2.2 1.0 3.2 3.1 1.0 6.8 2.5 1.1 9.7 4.3 3.7 4.3 3.8 1.9 4.5 1.2 5.9 2.7 1.3 2.8 1.4 61.8 1.9 5.9 2.4 2.5 1.0 1.3 39.2 1.7 3.7 1.2 2.0 3.9 2.0 6.2 0.5 29.7 2.1 1.4 0.7 1.0 0.6 1.9 1.3 0.7 0.3 0.4 4.5 0.8 5.8 1.5 2.4 1.1 2.1 1.6 3.0 1.3 0.5 2.0 1.8 5.6 2.2 2.4 0.6 6.2 2.1 3.1 3.8 2.0 1.7 3.6 1.8 3.1 11.1 0.9 3.2 1.0 0.7 0.6 73.6 6.9 1.8 0.4 2.2 0.5 9.3 2.7 2.5 3.1 0.5 1.5 0.6 0.9 1.4 1.7 1.4 0.6 1.5 1.3 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.5 3.4 2.7 5.0 4.4 3.1 3.2 3.1 4.3 2.8 5.9 3.7 3.2 0.0 0.0 1.0 0.7 0.3 0.4 0.1 0.6 1.0 0.3 0.4 0.1 0.0 0.1 0.0 2.1 0.5 0.4 0.0 0.0 0.1 2.6 0.3 0.2 0.8 0.0 0.8 19.7 0.0 0.6 0.3 21.9 0.4 0.0 0.0 1.4 0.0 0.1 0.0 10.3 0.0 0.0 0.0 0.0 4.0 0.3 0.2 0.0 26.2 0.0 0.6 0.0 5.5 7.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.6 0.0 0.6 0.4 0.4 0.4 0.8 0.0 4.0 0.3 0.0 0.0 1.1 ACER3 "APHC, FLJ11238, PHCA" ENSG00000078124 "Alkaline ceramidase 3" Q9NUN7 11 76860859-77026797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 335.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070087 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA070087: AB_2732147" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (9.54e-3)" "unprognostic (1.37e-1)" "unprognostic (4.06e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (7.13e-2)" "unprognostic (2.35e-3)" "unprognostic (8.45e-3)" "unprognostic (1.30e-1)" "unprognostic (3.68e-3)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.24e-2)" "unprognostic (3.37e-1)" "unprognostic (9.88e-2)" "unprognostic (7.97e-2)" 10.9 3.0 6.2 4.8 8.5 3.0 5.4 8.5 9.3 5.2 4.0 6.4 6.2 4.2 3.1 6.9 4.1 3.2 3.4 6.3 8.5 4.7 2.5 8.0 4.2 8.6 7.1 2.3 2.9 3.5 2.1 6.2 9.5 4.1 5.5 2.3 4.2 2.3 1.6 2.9 4.6 3.9 8.4 5.6 3.4 6.0 7.3 2.2 3.3 1.2 3.8 4.5 4.4 12.0 7.3 7.7 6.4 7.6 29.2 14.0 5.7 11.2 10.7 8.2 9.2 6.0 7.3 6.4 8.4 8.0 10.3 12.9 10.9 10.6 10.0 8.6 4.3 9.0 4.8 3.6 8.1 9.3 15.0 6.3 5.0 11.8 10.9 4.8 16.8 5.8 6.1 4.2 9.9 5.9 0.7 6.2 3.6 19.3 8.8 4.3 22.8 5.0 6.8 7.2 2.2 5.5 13.9 12.6 3.5 4.9 10.7 5.1 22.2 8.2 6.4 23.3 8.3 3.1 7.1 8.6 5.1 4.7 8.9 0.1 4.3 2.5 0.7 3.1 0.8 1.2 0.5 0.9 4.6 0.4 0.3 0.4 0.9 0.2 2.4 1.5 1.2 1.6 6.2 8.5 8.5 9.3 6.3 8.5 8.6 7.1 9.5 8.4 7.3 12.0 32.4 41.7 35.0 52.9 11.5 31.9 21.4 17.0 33.0 18.8 11.3 11.0 7.5 11.5 27.6 9.2 10.4 13.6 11.3 54.6 7.9 15.5 66.8 6.3 29.0 29.4 2.4 13.5 65.0 17.6 7.5 17.0 26.0 11.5 83.5 30.9 27.8 10.0 44.4 43.7 71.9 30.5 18.3 64.1 67.1 31.7 20.2 64.0 17.8 61.8 40.0 11.3 12.3 159.3 335.1 18.6 37.9 25.9 8.6 15.6 20.0 15.3 12.3 10.0 6.6 17.0 21.0 69.8 25.9 26.3 16.8 26.8 15.2 7.2 20.1 24.1 ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 320.5;breast: 278.2" "Group enriched" "Detected in many" 5 "Adipocytes: 383.6;Endothelial cells: 523.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 44.4;HSkMC: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" 320.5 13.4 17.7 42.0 21.8 14.5 278.2 34.6 25.5 141.7 21.6 67.0 15.3 125.0 21.5 63.6 121.2 59.2 42.2 18.4 18.6 34.5 1.8 146.8 49.3 21.4 17.7 21.4 15.8 9.7 11.6 10.4 23.2 72.9 19.4 23.7 61.3 24.5 51.7 85.3 60.9 107.7 24.9 82.1 57.0 8.6 17.0 33.2 47.7 30.2 40.8 112.4 113.1 22.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 44.4 0.0 0.0 5.5 0.0 0.0 30.7 0.0 0.0 3.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 21.8 34.6 25.5 18.4 18.6 21.4 17.7 23.2 24.9 17.0 22.0 383.6 6.4 10.8 1.6 1.0 0.0 1.7 0.0 2.8 78.4 3.6 3.7 15.1 0.0 1.8 0.0 2.1 0.4 0.8 0.0 0.0 0.0 2.2 0.4 1.0 523.8 0.0 81.3 3.6 9.8 0.2 18.9 0.0 0.4 5.1 0.0 7.5 0.0 1.1 6.7 3.2 0.0 0.0 0.8 0.0 3.7 1.2 2.2 0.0 1.0 0.0 5.9 0.0 0.5 0.3 0.0 0.0 0.4 0.1 2.2 0.0 0.1 0.7 3.7 0.0 3.9 4.5 0.2 0.5 4.0 0.0 0.1 1.1 0.1 0.0 2.3 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 374.2;Proximal tubular cells: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 88.8 81.6 154.2 38.6 152.2 32.0 52.4 153.0 190.0 39.5 160.1 94.4 162.9 42.0 26.1 60.4 53.6 36.5 567.7 155.2 153.1 138.9 73.9 40.7 40.5 146.1 145.3 30.8 53.8 233.8 33.6 30.5 147.8 41.2 69.6 46.9 72.0 49.5 660.4 45.5 158.5 43.7 152.5 44.7 110.2 35.1 186.3 38.0 53.7 695.8 43.3 52.5 42.4 159.6 47.2 55.8 56.5 116.3 101.2 69.8 78.7 43.7 60.9 79.0 71.9 81.2 63.5 115.7 72.2 70.6 60.3 109.8 108.8 88.3 42.8 75.8 80.2 51.0 73.7 95.0 86.7 147.8 77.8 120.8 64.4 78.9 83.2 61.7 81.2 61.5 72.9 118.4 65.4 91.7 73.7 47.9 37.0 282.6 115.1 102.3 37.8 162.1 106.8 97.3 37.8 33.9 112.2 128.7 82.0 44.9 74.9 74.7 55.5 60.0 68.7 50.2 45.0 64.7 92.1 80.6 102.0 64.0 66.5 10.3 52.9 18.1 32.0 76.4 29.3 49.4 25.5 34.9 69.0 46.4 29.2 30.8 9.0 39.4 97.1 24.0 41.2 58.6 154.2 152.2 153.0 190.0 155.2 153.1 146.1 145.3 147.8 152.5 186.3 159.6 26.3 25.6 31.8 45.4 49.4 18.7 54.5 102.7 31.3 60.6 28.0 23.2 9.1 64.3 63.5 60.7 81.3 100.3 33.3 190.8 131.0 58.3 14.5 37.2 17.7 26.1 53.2 30.3 28.8 42.6 60.0 24.0 77.5 37.1 40.6 56.7 20.7 64.6 91.5 53.8 34.0 99.1 89.5 35.5 26.4 8.9 24.2 39.2 35.6 7.5 68.3 73.9 34.0 12.1 20.9 43.9 103.5 27.8 63.2 34.4 374.2 285.7 59.2 73.5 59.2 28.6 38.4 26.4 38.2 35.8 16.1 193.2 30.7 54.4 113.6 64.9 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 26.4;Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.6;MCF7: 14.1;SK-BR-3: 27.9;T-47d: 69.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 4.9 1.4 3.7 1.1 3.7 0.6 4.6 4.2 4.3 3.9 2.4 3.0 4.3 0.8 2.6 1.5 0.9 0.9 0.9 3.6 2.9 15.0 16.8 3.6 1.3 3.1 2.7 0.9 1.5 1.0 0.4 1.8 3.3 1.4 3.4 0.8 1.7 1.8 0.6 0.6 3.3 1.5 2.5 1.5 2.0 2.2 2.9 1.0 1.3 0.6 1.3 1.2 0.9 3.2 10.7 2.9 0.3 0.1 1.3 0.6 0.0 0.6 0.0 0.7 1.2 0.3 17.6 0.0 0.6 1.0 0.0 1.1 0.0 0.1 0.1 5.8 0.1 0.0 3.5 0.0 2.0 0.0 9.5 0.8 1.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.6 14.1 0.3 1.9 0.9 3.7 2.8 0.0 0.0 0.0 0.4 5.2 1.5 0.3 6.9 27.9 2.1 0.1 69.7 10.5 0.2 0.0 6.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 11.5 0.0 1.4 14.7 0.6 7.3 2.1 6.9 8.4 0.4 3.3 4.0 8.5 0.0 7.2 0.2 0.9 7.2 5.3 3.7 3.7 4.2 4.3 3.6 2.9 3.1 2.7 3.3 2.5 2.9 3.2 0.4 0.0 2.7 1.0 1.0 0.3 1.1 3.8 1.2 0.2 5.5 4.2 1.7 7.2 2.8 11.0 0.0 15.9 3.6 8.3 15.6 4.2 1.8 4.1 1.1 0.5 0.0 0.0 1.4 9.2 13.8 1.5 3.1 5.6 5.7 4.1 0.0 26.4 11.2 1.7 0.8 3.2 8.2 3.0 0.3 5.3 0.3 2.1 0.0 1.9 1.0 0.7 11.3 0.5 0.3 6.2 2.6 0.4 1.5 1.1 15.7 59.8 2.9 0.5 0.0 1.5 1.1 3.2 15.8 2.6 0.3 4.5 5.1 0.4 2.6 1.3 ACOX1 PALMCOX ENSG00000161533 "Acyl-CoA oxidase 1" Q15067 17 75941507-75979177 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 191.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 199.8;Hepatocytes: 287.4;Proximal enterocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 77.2;neutrophil: 113.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 113.7" "Cell line enhanced" "Detected in all" "BEWO: 96.9;RT4: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021094, HPA021192, HPA021195, HPA028759" Approved Approved Nucleoli,Peroxisomes NA NA 96000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" Peroxisomes Nucleoli "CAB021094: AB_10261667, HPA021192: AB_1844527, HPA021195: AB_1844528, HPA028759: AB_10601352" "unprognostic (7.47e-2)" "unprognostic (3.69e-1)" "unprognostic (1.25e-3)" "unprognostic (1.36e-1)" "unprognostic (7.49e-2)" "unprognostic (8.14e-2)" "unprognostic (3.75e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "prognostic favorable (5.25e-7)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.72e-1)" "unprognostic (4.46e-2)" 37.8 18.1 16.1 10.6 18.2 8.8 17.1 17.4 15.1 11.0 21.3 40.9 62.5 9.3 9.8 30.4 9.9 14.9 23.0 14.3 17.5 40.3 191.5 13.6 6.2 16.6 17.9 9.5 39.7 18.8 12.6 17.3 15.9 18.4 27.1 16.1 15.4 11.8 30.1 24.8 51.4 11.1 17.5 10.5 27.4 9.3 20.6 8.3 17.0 29.2 12.1 19.5 12.7 18.9 16.3 24.5 7.2 9.9 34.0 14.4 96.9 11.8 11.3 12.9 14.8 16.4 24.0 9.1 14.0 17.9 12.5 9.9 28.7 12.4 19.2 10.0 9.5 10.9 13.1 47.2 19.4 9.7 7.8 24.0 9.4 15.7 9.2 13.1 32.3 13.6 12.3 8.9 14.0 45.3 26.3 7.0 4.9 36.8 19.8 13.4 21.3 10.2 20.7 129.1 8.7 12.6 30.6 46.5 11.4 21.2 32.6 11.3 20.9 18.2 13.4 15.2 11.5 14.4 11.0 4.0 10.0 9.7 11.4 77.2 18.3 5.2 6.9 14.2 8.2 5.4 6.6 8.8 10.3 4.5 7.2 7.1 113.7 7.2 9.4 9.4 9.3 8.0 16.1 18.2 17.4 15.1 14.3 17.5 16.6 17.9 15.9 17.5 20.6 18.9 28.0 28.9 25.0 25.1 10.8 13.5 15.9 26.1 21.1 27.4 19.4 13.5 47.4 51.5 23.4 23.9 22.9 37.7 12.1 199.8 21.5 22.9 11.6 18.1 16.7 18.8 34.4 21.5 17.8 40.6 46.5 19.8 88.7 24.1 17.1 21.4 21.8 287.4 25.4 18.5 18.8 44.5 24.4 35.4 14.1 7.1 29.8 23.7 14.2 15.0 36.3 61.9 9.2 22.1 18.2 34.2 100.0 47.0 18.3 24.0 238.7 107.8 17.4 28.4 0.0 18.4 17.2 5.5 11.0 28.5 30.3 43.2 13.2 17.1 41.9 31.7 ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368298 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 76 "prostate: 3643.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Hofbauer cells: 4.7;Syncytiotrophoblasts: 8.9" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 139.7" "Lineage enhanced" "Detected in many" "granulocytes: 139.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.7;OE19: 22.3;RPMI-8226: 58.0;U-698: 17.2;U-87 MG: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" NA NA 460000 480000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 3.1 5.4 0.9 7.3 1.3 17.5 3.4 0.9 0.9 6.3 1.2 3.6 3.1 1.4 17.2 47.7 2.2 1.5 0.6 1.2 1.5 28.9 1.4 4.5 1.9 1.5 1.3 1.1 2.7 3.9 0.5 10.8 1.5 3643.7 6.5 0.4 10.6 0.8 0.2 27.0 3.4 1.8 1.0 1.8 3.2 2.4 1.0 1.0 2.4 0.2 6.5 1.8 12.1 1.7 0.5 0.1 0.0 0.0 0.2 0.9 11.7 0.3 17.7 0.1 0.0 0.4 0.4 10.6 0.8 0.0 0.1 4.8 0.0 0.1 0.0 0.1 0.5 2.0 0.4 0.2 0.2 7.3 0.1 1.1 1.6 0.1 0.0 0.2 0.0 0.0 0.1 2.7 0.2 0.1 0.0 13.5 0.7 22.3 2.1 0.1 0.0 58.0 5.0 6.5 0.0 4.1 0.1 2.0 0.6 1.7 0.3 6.5 0.0 0.1 0.1 2.5 0.1 0.8 0.4 17.2 14.9 12.7 0.2 0.1 30.2 139.7 0.2 26.9 0.2 0.7 0.0 0.0 35.3 0.0 0.0 0.0 26.4 2.6 25.8 2.4 0.0 10.1 0.9 1.3 0.9 0.9 1.2 1.5 1.5 1.3 1.5 1.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.9;Endometrial ciliated cells: 159.9;Glandular and luminal cells: 292.3;Proximal enterocytes: 462.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 138.8;RT4: 143.3;U-937: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 23.8 4.2 13.1 29.0 12.6 16.2 21.3 13.0 15.5 51.4 10.4 111.7 358.9 30.3 217.8 7.9 45.0 21.5 9.4 12.1 13.4 9.0 165.5 35.6 28.0 14.4 13.1 17.0 5.5 2.2 2.6 8.6 14.9 12.3 116.6 1.5 5.5 20.3 3.9 3.4 418.0 15.5 14.0 25.7 44.2 9.6 15.3 16.4 7.2 8.8 28.0 76.3 7.6 13.2 38.6 0.9 0.7 0.1 2.5 0.4 3.3 1.1 7.3 0.3 0.6 34.8 138.8 46.7 8.4 1.9 6.8 0.3 0.0 0.2 0.8 39.4 0.0 36.5 1.3 60.9 8.8 57.3 59.2 5.9 0.0 0.8 0.0 2.7 2.8 0.0 0.1 20.6 0.1 0.0 0.1 26.3 0.1 32.2 1.3 12.9 0.2 28.6 3.8 143.3 0.1 0.9 55.8 21.0 0.1 0.1 0.1 31.7 40.5 0.5 0.4 2.2 2.5 14.8 0.1 22.6 1.2 70.5 0.1 27.4 15.1 27.5 25.2 27.9 24.9 16.3 20.4 27.8 31.1 13.1 13.8 21.4 3.9 26.1 27.7 9.8 41.5 21.1 13.1 12.6 13.0 15.5 12.1 13.4 14.4 13.1 14.9 14.0 15.3 13.2 23.4 12.8 51.3 0.0 20.1 3.8 10.3 10.7 8.6 0.1 7.0 4.6 1.7 12.8 23.6 0.0 4.2 1.8 10.5 164.9 0.0 13.3 92.6 159.9 37.6 24.7 40.8 10.7 1.3 6.4 2.6 5.7 41.8 292.3 17.2 0.5 16.1 88.6 18.9 0.0 1.1 79.0 0.0 22.4 57.8 42.6 15.8 24.9 3.6 17.8 11.5 0.1 16.5 1.0 1.0 48.0 122.4 12.0 20.3 7.1 462.5 0.2 8.2 1.2 0.0 0.8 3.3 4.0 1.9 3.3 1.7 0.7 24.0 6.4 103.3 50.0 ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.6;brain: 32.0;retina: 45.8;testis: 20.7" "Cell type enhanced" "Detected in many" "Astrocytes: 229.2;Cone photoreceptor cells: 229.4;Erythroid cells: 110.5;Inhibitory neurons: 110.6;Rod photoreceptor cells: 130.0" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Group enriched" "Detected in some" 5 "SCLC-21H: 7.6;U-937: 6.2" HPA040470 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" 0.2 4.2 14.8 1.4 18.3 22.6 0.2 26.3 32.0 0.1 1.2 0.5 4.7 0.1 0.5 0.3 0.2 0.3 1.4 18.6 12.8 1.9 2.0 0.3 2.4 22.2 18.2 0.0 1.1 11.3 4.2 0.6 18.9 0.3 0.3 45.8 0.3 18.0 2.3 0.1 2.4 0.1 13.8 1.1 0.6 20.7 25.0 0.6 0.4 1.4 1.0 0.2 0.1 14.3 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.1 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.2 6.2 0.3 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.7 1.6 0.0 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 0.3 14.8 18.3 26.3 32.0 18.6 12.8 22.2 18.2 18.9 13.8 25.0 14.3 0.6 25.6 29.2 229.2 1.4 1.9 1.5 0.0 2.2 65.2 2.1 0.4 0.0 1.5 16.1 1.8 229.4 0.3 3.3 0.6 7.9 0.6 43.7 0.3 0.1 3.9 2.4 110.5 70.6 0.2 0.1 4.2 0.0 0.2 10.1 0.2 1.8 8.4 0.1 21.9 110.6 1.8 0.0 1.0 15.9 7.9 0.3 6.4 0.0 15.9 0.9 24.5 0.0 41.7 9.8 0.3 1.6 1.9 0.8 1.1 1.8 0.4 8.1 130.0 0.0 2.3 1.1 45.3 1.7 0.1 1.3 0.3 15.3 0.1 0.4 1.3 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 276.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 237.8" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 5.3;ASC TERT1: 11.5;HSkMC: 13.8;U-87 MG: 8.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 25.5 2.5 7.1 0.6 5.2 0.6 10.7 4.7 5.0 2.8 3.0 3.7 0.8 1.2 7.1 1.0 1.7 2.3 3.3 5.5 7.9 25.4 276.6 2.1 1.9 6.3 6.8 0.8 0.6 1.0 0.5 1.4 6.8 0.6 1.2 0.5 0.9 0.9 13.9 2.3 1.9 1.0 6.7 4.6 3.4 0.9 8.2 0.7 4.2 1.7 0.7 1.1 2.2 8.2 0.0 0.0 0.1 0.1 5.3 11.5 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 13.8 0.0 0.8 0.1 0.2 0.0 0.0 0.1 0.5 1.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 8.5 0.1 0.0 0.1 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 7.1 5.2 4.7 5.0 5.5 7.9 6.3 6.8 6.8 6.7 8.2 8.2 0.4 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.5 0.5 0.0 0.3 1.2 0.0 13.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 6.1 237.8 3.7 0.0 0.2 0.0 0.0 11.7 1.5 0.8 9.3 3.5 0.0 7.5 1.3 0.9 0.0 1.5 0.1 0.0 0.0 6.0 0.0 0.2 0.0 52.1 0.0 0.1 0.0 11.3 0.3 0.2 0.3 0.1 0.6 0.0 0.7 0.9 0.1 0.2 ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 117.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 137.7;Hepatocytes: 138.9;Intestinal goblet cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.3" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.3;monocytes: 21.8" "Cell line enhanced" "Detected in many" "HBEC3-KT: 132.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved NA NA 16000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" 69.3 23.7 4.0 10.7 9.3 7.5 27.2 6.8 7.8 15.1 6.0 54.6 64.2 13.7 34.3 18.6 22.1 10.7 49.8 3.3 6.4 22.0 46.9 23.2 4.0 12.1 5.9 13.0 14.8 19.6 3.8 17.2 12.7 12.2 32.9 5.3 38.1 16.2 117.3 17.1 46.8 11.3 5.1 8.1 37.7 10.6 7.2 4.0 9.6 99.2 7.0 9.3 11.9 16.3 32.8 11.6 17.1 10.7 69.5 59.1 25.5 14.5 32.4 13.9 21.7 27.3 40.6 0.1 18.6 24.1 50.2 26.0 20.1 132.4 9.5 0.1 7.1 37.2 6.6 18.5 46.2 6.6 28.1 50.3 34.2 24.8 34.5 27.8 27.7 4.2 22.0 7.1 15.8 13.3 2.4 18.8 3.3 27.6 44.1 15.9 20.3 83.4 62.5 9.0 2.9 14.5 24.7 49.1 32.1 21.2 19.6 24.4 23.5 12.3 7.8 12.4 7.9 24.0 19.7 9.1 32.3 9.3 9.1 34.3 21.8 6.6 1.2 13.3 1.2 0.7 3.0 1.3 22.6 1.1 5.3 2.9 12.2 0.7 6.4 4.2 2.0 9.2 4.0 9.3 6.8 7.8 3.3 6.4 12.1 5.9 12.7 5.1 7.2 16.3 8.8 12.8 41.1 17.6 4.2 7.8 9.4 13.5 10.2 6.4 27.6 10.9 82.2 20.0 16.6 11.0 6.2 15.5 3.7 137.7 11.7 20.8 9.0 8.0 8.2 13.5 7.8 29.0 18.5 33.7 11.2 11.4 58.1 13.0 9.5 35.3 13.6 138.9 16.4 8.4 18.2 100.6 18.3 17.9 13.9 7.2 11.5 15.6 14.2 17.8 19.4 9.1 1.0 5.5 86.5 23.4 66.4 4.5 14.6 11.2 70.4 60.5 7.6 4.1 13.1 7.2 9.8 32.1 20.3 12.3 10.9 20.9 5.1 7.8 75.1 13.0 ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261210 "Enzymes, Metabolic proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 46.5;Astrocytes: 167.8;Early spermatids: 52.9;Hepatocytes: 53.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "basophil: 7.0;neutrophil: 2.2" "Lineage enriched" "Detected in single" 70 "granulocytes: 7.0" "Cell line enhanced" "Detected in many" "ASC diff: 14.3;ASC TERT1: 16.1;Hep G2: 42.6;hTERT-RPE1: 14.0;RH-30: 19.1;SK-BR-3: 18.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA039353: AB_2676460, HPA047956: AB_2680223, HPA061517: AB_2684549" "unprognostic (8.59e-2)" "unprognostic (9.29e-4)" "unprognostic (1.47e-1)" "unprognostic (9.37e-3)" "unprognostic (2.46e-2)" "unprognostic (2.21e-1)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (7.79e-2)" "prognostic favorable (0.00e+0)" "unprognostic (6.16e-4)" "unprognostic (1.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-4)" 22.7 14.5 5.2 1.5 5.1 0.1 7.3 5.2 5.3 8.3 9.3 2.2 0.7 9.1 12.1 1.5 8.0 8.1 6.8 4.7 4.9 25.9 40.0 6.4 1.5 5.5 6.4 16.7 2.0 13.7 4.4 4.0 5.2 5.7 1.0 4.8 12.1 5.5 3.5 1.7 1.5 6.3 4.9 2.1 1.4 2.3 6.5 1.1 8.8 5.7 1.1 2.8 5.0 5.5 0.0 0.2 3.4 0.0 14.3 16.1 0.1 2.2 11.0 1.7 1.9 0.4 0.1 0.0 0.0 5.0 5.2 0.1 0.0 0.0 1.0 0.0 2.2 0.0 0.0 42.6 4.8 0.1 0.0 10.8 0.0 0.5 0.0 14.0 0.4 0.0 0.0 0.0 7.8 1.0 0.1 0.2 4.8 0.0 0.0 0.0 19.1 2.7 0.1 0.1 3.1 0.0 0.0 18.0 0.1 7.1 7.9 0.5 0.0 2.8 2.7 0.2 1.2 0.1 0.1 0.1 3.5 0.0 3.4 7.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 5.2 5.1 5.2 5.3 4.7 4.9 5.5 6.4 5.2 4.9 6.5 5.5 1.3 22.4 46.5 167.8 0.2 0.9 9.5 0.0 2.2 37.8 5.6 3.0 21.8 14.3 3.2 12.9 4.2 1.5 0.1 0.1 5.9 6.4 52.9 3.9 14.8 1.5 0.0 0.0 1.5 2.9 0.8 12.1 0.0 2.7 0.0 8.8 1.8 53.6 0.7 28.6 1.6 0.1 0.0 3.2 0.6 9.4 23.9 0.8 0.0 35.6 0.1 16.4 0.0 16.6 0.7 0.1 0.1 23.7 0.0 3.0 1.1 31.7 3.7 5.3 6.6 18.6 9.9 4.6 0.6 0.4 0.1 0.5 0.6 13.2 1.2 3.7 ACTB ENSG00000075624 "Actin beta" P60709 7 5526409-5563902 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 22882.9;Pancreatic endocrine cells: 14370.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002621, HPA041264, HPA041271" Supported NA NA 5800000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "CAB002621: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (1.66e-1)" "unprognostic (1.15e-1)" "unprognostic (4.20e-2)" "unprognostic (1.15e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (9.80e-3)" "unprognostic (1.57e-3)" "unprognostic (1.73e-1)" "unprognostic (5.99e-2)" "unprognostic (3.33e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (3.78e-5)" "unprognostic (2.68e-2)" "unprognostic (3.20e-1)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" 2558.1 1235.8 2143.2 4250.8 2321.0 3598.4 2009.8 2400.1 2776.1 2274.6 2183.3 6581.2 1659.0 5033.9 1630.3 2928.9 2943.6 1772.1 817.6 2355.6 2315.8 1313.6 1759.9 2876.0 4394.2 2654.8 2338.9 1711.5 761.9 838.5 731.4 1817.2 2569.2 2027.1 2338.4 488.2 1470.2 2943.2 465.1 1541.7 2825.9 5736.8 2457.9 3009.5 2869.7 558.3 2483.4 3278.4 1317.9 524.0 4602.3 3720.8 2223.5 3045.4 7791.1 5198.8 5604.1 4658.2 2321.1 3120.3 6654.3 6049.6 4853.2 6209.7 4619.4 8249.5 4361.9 4522.7 4557.0 9445.4 4904.8 4820.3 3279.5 9453.9 4507.4 5324.6 1668.7 3974.3 4579.6 4520.6 3538.8 4733.2 9853.8 4098.5 2786.7 6863.0 1738.0 4128.6 5073.2 3561.3 2189.7 3513.0 6603.4 7531.9 4055.1 13162.1 6813.7 2468.5 3490.8 5658.6 3351.4 3419.7 5904.6 3175.8 1633.1 2746.9 5754.7 5822.1 2400.3 5088.3 5859.7 5314.8 7975.3 10437.4 7019.9 7000.1 8802.8 1902.3 2442.5 5082.1 5772.0 6622.6 12412.7 14674.1 18104.2 29636.6 10647.1 19648.6 8327.7 5139.6 7639.4 9512.9 19292.5 4844.1 5592.0 7894.3 18040.6 6233.1 22870.8 7122.2 11463.2 37406.8 2143.2 2321.0 2400.1 2776.1 2355.6 2315.8 2654.8 2338.9 2569.2 2457.9 2483.4 3045.4 2775.4 1150.6 680.4 142.4 4118.9 5737.0 9776.6 5792.0 3110.2 146.7 1564.0 2047.2 145.3 1080.9 2763.3 2144.5 85.5 3647.7 3989.3 3419.3 2277.4 6508.8 101.3 1422.1 2344.0 2768.4 1451.5 3170.9 129.3 6365.4 12480.2 2958.5 3136.1 2041.6 1539.9 2372.0 2163.5 2590.6 13977.7 269.2 101.3 2006.7 3694.5 7392.0 11420.0 199.7 1766.7 8486.4 2995.4 259.5 22882.9 1654.4 5237.9 116.1 302.2 14370.0 2899.8 2680.3 3040.4 4764.9 4968.2 2149.2 1453.8 146.7 3287.0 1398.2 5423.9 133.8 381.9 4376.1 4722.2 3257.7 5961.7 1688.9 1966.6 6941.4 ACTRT3 ARPM1 ENSG00000184378 "Actin related protein T3" Q9BYD9 3 169766921-169769561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 47.5" "Cell type enriched" "Detected in many" 6 "Early spermatids: 1021.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 18.1;HSkMC: 11.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA035817, HPA035818" Approved Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA035817: AB_10671938, HPA035818: AB_2674801" "unprognostic (2.35e-1)" "unprognostic (9.39e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (1.89e-2)" "unprognostic (1.75e-1)" "unprognostic (3.29e-1)" "unprognostic (1.24e-1)" "unprognostic (7.31e-4)" "unprognostic (2.64e-1)" "unprognostic (9.16e-2)" "unprognostic (4.41e-2)" "unprognostic (8.03e-2)" "unprognostic (8.49e-2)" "unprognostic (1.63e-1)" "unprognostic (8.25e-3)" "unprognostic (2.22e-1)" 1.6 0.9 1.7 0.7 2.1 0.4 1.1 2.6 4.5 1.4 2.0 0.9 1.1 1.1 0.8 1.0 2.0 0.9 1.2 2.2 2.0 2.4 2.7 1.1 0.8 2.1 3.5 1.6 0.6 1.2 1.3 1.0 2.2 1.2 0.8 0.8 0.6 1.9 0.7 0.4 0.8 1.6 1.8 0.4 1.2 47.5 2.5 0.8 1.5 0.7 0.9 1.7 0.7 2.6 4.0 2.5 0.2 1.1 18.1 5.5 0.0 4.7 3.0 3.1 2.6 0.0 5.2 0.0 6.5 5.9 2.0 2.5 1.5 2.5 3.3 2.9 1.7 9.3 1.9 0.5 3.0 1.1 0.9 11.8 0.6 3.8 0.7 2.0 5.8 0.9 0.0 0.0 5.7 2.0 0.2 0.1 4.5 3.5 5.3 0.6 0.0 0.1 3.3 1.0 3.1 2.1 5.9 1.4 0.1 0.6 2.5 4.1 2.4 0.0 0.0 2.5 0.0 0.4 0.2 0.2 1.1 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.9 0.3 0.0 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.7 2.1 2.6 4.5 2.2 2.0 2.1 3.5 2.2 1.8 2.5 2.6 0.9 0.0 1.5 0.3 0.1 0.4 1.3 1.6 1.2 1.6 0.4 0.4 0.7 0.0 2.0 0.0 2.1 1.7 0.1 0.2 1.9 2.3 1021.8 1.1 0.6 1.8 0.0 0.4 0.2 2.1 1.3 1.7 0.5 0.9 1.3 1.3 2.2 2.1 1.5 3.3 0.2 1.3 0.0 0.8 0.7 161.0 9.6 2.2 1.8 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.1 5.7 0.2 0.7 0.5 2.8 2.1 1.3 13.1 1.1 1.4 24.6 4.6 1.2 0.0 0.8 1.3 3.8 1.2 0.4 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 31.3;brain: 10.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.2;Leydig cells: 31.7;Oligodendrocytes: 55.8;Proximal enterocytes: 17.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 10.9;HDLM-2: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 29.7" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 31.3 2.5 3.2 0.6 6.3 0.1 6.2 1.3 3.5 0.5 0.0 4.1 4.1 0.1 0.3 0.2 0.1 0.3 0.4 6.4 10.2 0.4 2.2 0.2 0.5 1.4 1.9 3.6 1.5 0.0 2.2 0.1 1.3 0.2 3.0 0.4 0.8 0.3 0.8 0.3 3.4 0.2 0.9 0.1 2.1 0.4 6.6 0.2 0.2 0.3 0.3 0.1 0.2 3.8 1.5 0.0 0.0 0.1 10.9 0.3 0.2 0.3 0.3 0.1 0.3 1.7 0.2 0.0 0.1 0.9 0.7 0.0 0.1 0.0 0.2 5.1 0.7 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.1 0.6 1.9 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.2 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.2 6.3 1.3 3.5 6.4 10.2 1.4 1.9 1.3 0.9 6.6 3.8 0.5 0.0 1.1 14.7 1.4 0.6 0.7 0.9 1.8 0.8 0.9 0.3 1.9 0.0 0.9 0.0 0.0 0.2 0.3 14.3 0.0 0.2 1.9 0.4 4.9 0.7 7.8 0.0 26.2 0.2 0.8 0.9 2.6 0.5 0.0 0.4 1.1 5.9 0.1 0.0 11.0 9.2 2.0 0.0 1.3 2.9 31.7 0.1 3.6 3.7 4.3 1.8 0.0 3.5 55.8 0.4 7.6 9.1 2.9 1.8 17.7 1.1 0.2 0.3 0.0 0.6 0.8 0.4 2.4 0.7 1.4 0.3 2.5 0.4 13.5 0.5 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAM8 "CD156, CD156A, MS2" ENSG00000151651 "ADAM metallopeptidase domain 8" P78325 10 133262420-133276868 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.6;lymphoid tissue: 48.5" "Cell type enhanced" "Detected in many" "dendritic cells: 54.7;Extravillous trophoblasts: 96.4;Langerhans cells: 124.9;monocytes: 81.3;NK-cells: 82.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 21.2" "Group enriched" "Detected in many" 5 "basophil: 107.4;eosinophil: 259.0;neutrophil: 139.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 259.0" "Cell line enhanced" "Detected in many" "A-431: 60.0;BEWO: 81.8;CAPAN-2: 70.4;HaCaT: 69.8;HDLM-2: 45.9;U-87 MG: 34.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA064637 Approved "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA064637: AB_2685306" "unprognostic (8.24e-2)" "unprognostic (6.07e-3)" "unprognostic (1.27e-3)" "unprognostic (5.18e-2)" "unprognostic (8.26e-2)" "unprognostic (6.47e-2)" "unprognostic (5.59e-2)" "unprognostic (2.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.94e-3)" "unprognostic (3.37e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (3.99e-10)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.28e-1)" "unprognostic (9.32e-2)" 5.6 2.4 2.1 22.1 2.3 68.6 2.7 1.4 21.2 4.2 1.7 3.6 5.8 2.2 2.1 3.5 6.0 5.1 2.5 1.8 1.8 4.7 8.4 21.5 11.6 3.2 1.9 3.0 4.3 0.3 3.6 3.1 4.4 4.5 1.6 1.5 4.2 1.1 1.2 3.2 11.3 2.1 1.6 48.5 11.5 2.6 5.9 4.0 3.8 1.7 8.2 11.9 3.2 3.4 60.0 1.7 0.5 0.9 0.4 0.1 81.8 0.7 1.4 0.3 0.4 4.6 70.4 1.0 1.7 0.1 0.5 69.8 0.2 11.9 0.1 45.9 1.0 0.8 0.5 0.0 0.7 3.6 15.9 0.2 1.1 0.6 1.0 3.7 0.1 0.5 3.2 2.4 0.0 4.8 0.2 20.2 0.3 7.1 1.7 0.4 0.7 6.6 0.8 1.4 0.1 0.8 0.4 0.2 1.0 1.1 1.0 2.0 1.7 0.0 1.5 0.6 1.0 3.4 2.2 0.6 34.5 2.0 0.2 107.4 24.8 259.0 22.2 9.2 15.9 10.2 14.8 21.4 37.2 5.6 5.6 8.2 139.4 24.7 9.4 0.7 16.9 25.2 2.1 2.3 1.4 21.2 1.8 1.8 3.2 1.9 4.4 1.6 5.9 3.4 1.3 3.2 10.5 3.3 23.2 7.8 6.6 14.3 0.0 4.3 2.2 1.8 2.4 2.8 9.5 0.0 8.4 7.7 54.7 0.3 1.9 3.1 1.0 1.5 0.9 1.7 0.0 5.7 3.5 2.7 96.4 2.4 6.1 2.1 12.6 1.1 2.5 2.4 23.3 0.0 3.0 0.6 2.0 8.8 124.9 0.4 0.9 33.9 7.2 0.0 81.3 0.2 82.4 2.0 2.9 39.1 0.1 0.0 20.7 11.0 0.3 0.5 10.0 5.1 0.0 0.8 1.0 1.5 0.8 0.6 6.5 20.0 39.4 0.2 0.5 42.5 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 ADAMTS15 ENSG00000166106 "ADAM metallopeptidase with thrombospondin type 1 motif 15" Q8TE58 11 130448974-130476641 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 26.4" "Cell type enhanced" "Detected in some" "Adipocytes: 8.6;Cardiomyocytes: 11.0;Endometrial stromal cells: 15.6;Fibroblasts: 9.6;Gastric mucus-secreting cells: 8.2;Glandular and luminal cells: 7.5;Granulosa cells: 6.8;Skeletal myocytes: 6.9" "Cancer enhanced" "Detected in many" "breast cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 72.0;ASC TERT1: 43.0;EFO-21: 36.6;hTERT-RPE1: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA042867 Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA042867: AB_10794535" "unprognostic (7.64e-2)" "unprognostic (1.49e-3)" "unprognostic (7.15e-2)" "unprognostic (1.34e-3)" "unprognostic (1.07e-3)" "unprognostic (7.07e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.72e-4)" "unprognostic (6.18e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (7.40e-2)" "unprognostic (1.29e-2)" "unprognostic (5.95e-3)" "unprognostic (6.68e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.63e-5)" 26.4 1.2 0.4 1.7 0.5 0.0 15.3 0.4 0.8 3.4 1.7 3.2 0.5 4.3 1.3 3.7 9.8 2.3 14.5 0.4 0.9 11.0 0.4 7.2 1.1 4.4 0.6 2.7 1.4 0.4 1.3 16.9 1.5 1.9 1.9 0.2 1.3 1.1 1.8 5.0 3.6 4.6 1.0 2.3 5.5 0.9 1.2 1.1 7.0 1.0 0.3 8.8 2.6 1.0 0.0 2.6 1.6 0.8 72.0 43.0 0.0 2.7 5.2 1.0 0.2 0.5 1.2 0.0 36.6 0.2 2.6 7.0 0.6 0.7 0.2 0.0 1.7 0.0 3.3 0.0 0.7 0.0 0.0 14.1 0.0 0.6 0.1 19.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 8.1 1.3 0.0 5.7 0.0 4.1 0.0 0.1 0.1 0.6 0.0 12.1 0.0 0.0 5.2 3.9 0.0 0.0 0.6 8.5 7.0 3.5 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.8 0.4 0.9 4.4 0.6 1.5 1.0 1.2 1.0 8.6 0.0 0.0 0.3 0.2 0.5 0.1 3.5 0.0 1.3 5.6 2.7 11.0 0.0 0.5 1.8 0.0 0.6 0.0 1.0 0.0 0.0 0.0 4.4 15.6 1.7 0.0 0.0 0.4 0.8 0.6 9.6 8.2 7.5 0.0 6.8 0.4 0.1 0.9 0.0 1.6 0.5 2.0 0.0 0.3 0.0 5.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.9 0.7 0.0 0.0 0.1 1.0 0.5 0.0 0.0 6.9 3.6 0.2 0.3 0.0 0.3 0.8 0.1 0.0 1.8 0.1 ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;placenta: 20.6" "Cell type enhanced" "Detected in some" "Adipocytes: 36.8;Granulosa cells: 15.0;Muller glia cells: 13.7;Oligodendrocytes: 16.9;Rod photoreceptor cells: 7.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 11.6;HUVEC TERT2: 8.0;SuSa: 10.6;TIME: 2.5;U-87 MG: 4.8" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Yes NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" 3.1 0.1 1.3 0.3 3.0 0.0 2.9 11.0 2.5 1.2 0.5 0.0 0.1 0.8 0.0 0.1 0.2 0.6 0.0 1.8 2.7 0.2 0.0 0.1 0.1 4.3 2.4 0.1 0.3 0.0 0.8 20.6 3.7 0.4 0.0 2.0 1.3 0.1 0.6 0.1 0.0 0.6 1.7 0.0 0.0 0.2 2.4 0.9 0.0 0.0 0.0 0.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.6 0.0 0.5 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.0 11.0 2.5 1.8 2.7 4.3 2.4 3.7 1.7 2.4 5.9 36.8 0.0 0.0 4.6 0.1 0.1 0.1 0.0 0.0 1.8 1.5 4.3 0.6 0.0 0.0 1.8 2.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.3 0.0 15.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.1 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.0 0.0 ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Excitatory neurons: 50.2;Leydig cells: 19.9;Rod photoreceptor cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;AN3-CA: 7.8;HEL: 14.1;K-562: 12.3;SH-SY5Y: 7.0;U-2 OS: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Intermediate filaments" "HPA021368: AB_2670681, HPA021369: AB_2670682" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-3)" "unprognostic (6.11e-2)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (1.60e-3)" "unprognostic (5.92e-4)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (8.63e-3)" "unprognostic (1.65e-3)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-4)" 2.3 0.8 0.5 1.0 2.5 0.8 3.2 0.0 1.5 0.4 0.1 0.3 0.1 1.9 1.7 0.2 2.9 0.6 0.9 1.5 0.6 0.9 0.2 1.1 0.8 0.0 0.2 2.0 0.3 2.7 0.2 0.7 0.1 0.7 0.3 8.4 0.4 1.1 0.2 0.4 0.2 1.7 0.0 0.7 0.5 1.9 0.1 0.6 1.2 0.3 0.3 1.3 0.4 0.4 0.0 0.0 13.2 7.8 0.1 0.3 0.1 0.7 2.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.8 0.0 1.8 0.0 1.8 14.1 0.9 0.0 0.2 0.0 0.0 1.7 0.1 0.6 0.1 3.3 0.0 0.0 12.3 0.0 0.0 0.0 1.3 0.0 2.2 0.0 4.0 0.0 2.6 0.0 4.6 0.0 0.5 7.0 0.0 0.6 0.2 1.4 0.1 0.2 0.1 5.6 8.5 0.0 0.7 0.0 0.0 0.0 1.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.5 1.5 0.6 0.0 0.2 0.1 0.0 0.1 0.4 1.8 0.0 3.4 7.5 0.0 0.5 0.9 0.0 0.0 0.9 0.8 3.2 1.2 1.5 1.3 1.8 14.6 0.0 0.0 0.0 0.0 0.0 4.1 2.2 5.1 3.7 0.0 2.5 50.2 0.0 0.3 3.3 0.0 0.7 1.3 1.9 3.9 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.7 1.9 19.9 0.3 0.0 1.0 0.0 1.8 0.0 7.1 1.3 0.0 0.0 4.5 0.0 1.1 0.0 0.3 0.5 12.9 0.0 0.3 1.2 1.2 0.8 0.3 0.0 0.0 0.0 2.8 0.0 0.1 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 41.2" "Cell type enhanced" "Detected in many" "Adipocytes: 166.3;Astrocytes: 84.2;Basal prostatic cells: 87.2;Endometrial stromal cells: 179.1;Endothelial cells: 221.0;Prostatic glandular cells: 115.7;Smooth muscle cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 23.6;RPTEC TERT1: 27.1;SH-SY5Y: 128.3;SuSa: 40.5;WM-115: 28.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028567, HPA028577, HPA028601" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" No NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Endoplasmic reticulum" "HPA028567: AB_10599275, HPA028577: AB_10600330, HPA028601: AB_2672694" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (4.83e-2)" "unprognostic (3.08e-1)" "unprognostic (1.37e-2)" "unprognostic (7.80e-3)" "unprognostic (5.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (7.67e-2)" "unprognostic (3.16e-3)" "unprognostic (1.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-3)" "unprognostic (5.00e-3)" 41.2 4.8 4.0 12.2 5.0 0.1 19.0 5.5 5.3 16.2 7.9 8.1 1.2 13.2 1.1 5.3 10.2 7.8 15.6 4.4 5.6 9.5 2.7 13.6 1.9 10.8 8.1 7.3 9.8 6.3 2.2 31.7 8.5 7.9 2.7 1.4 3.2 3.7 7.4 2.6 3.7 12.1 8.0 4.1 4.7 0.8 8.1 1.0 7.3 7.3 1.1 22.5 9.0 6.4 0.0 1.2 13.9 0.0 0.6 0.1 1.3 0.2 0.0 0.0 0.0 1.9 0.0 0.0 2.3 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.9 0.0 8.8 2.6 0.0 0.0 0.5 0.0 23.6 0.0 0.5 0.0 0.3 0.1 0.0 0.0 7.5 1.1 0.0 0.0 2.4 0.1 27.1 0.3 0.1 128.3 0.0 0.0 0.0 40.5 0.0 0.7 5.4 0.8 0.4 0.0 0.8 0.0 0.0 0.0 0.5 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.0 5.5 5.3 4.4 5.6 10.8 8.1 8.5 8.0 8.1 6.4 166.3 3.2 4.8 84.2 0.0 17.5 87.2 0.0 4.6 0.0 6.9 15.9 6.6 2.8 2.6 38.6 2.1 1.0 0.2 1.1 0.0 69.7 0.9 13.2 179.1 221.0 1.2 0.0 4.2 3.3 0.6 31.4 1.5 33.8 0.0 8.4 27.1 0.3 7.5 0.0 14.3 1.1 0.0 0.3 20.1 0.4 2.5 2.7 26.6 21.5 0.0 0.2 0.0 26.7 0.6 45.5 1.0 2.2 0.0 115.7 0.0 10.8 0.1 0.1 0.0 20.7 94.8 0.3 0.7 1.3 13.5 1.6 3.2 12.1 0.9 36.7 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 9.8;Cardiomyocytes: 9.6;Leydig cells: 19.3;Peritubular cells: 18.0;Proximal enterocytes: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA044050: AB_10962625" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (5.85e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-3)" 1.8 1.5 1.7 0.7 2.2 0.3 2.2 2.3 2.0 33.0 8.3 3.2 9.8 19.8 5.0 15.1 9.5 0.5 20.7 1.8 0.4 1.5 4.2 1.4 0.6 0.8 1.0 1.3 1.0 1.4 2.6 4.2 0.6 4.5 1.1 0.9 3.9 3.3 15.1 2.1 8.4 12.5 0.2 0.8 1.4 3.6 1.6 0.2 1.5 5.9 1.5 3.8 22.5 1.4 8.1 3.5 0.1 0.1 4.1 3.0 3.8 14.7 9.8 5.6 8.1 20.7 4.0 0.0 3.6 12.3 1.6 6.7 3.5 4.2 4.2 7.9 0.4 1.7 11.0 3.8 4.6 0.2 10.2 1.8 4.6 1.3 3.5 7.4 0.0 2.5 5.0 9.8 0.6 7.5 0.4 0.4 0.1 2.3 1.8 0.2 0.8 2.1 4.5 0.0 0.1 0.3 3.5 0.4 4.4 1.9 9.2 3.0 0.9 0.0 5.4 10.9 0.6 6.2 4.2 1.0 0.1 0.8 2.4 0.2 0.0 0.4 1.4 0.5 0.9 0.0 1.6 1.1 0.0 0.0 2.0 1.3 0.1 0.0 0.9 0.0 0.5 0.5 1.7 2.2 2.3 2.0 1.8 0.4 0.8 1.0 0.6 0.2 1.6 1.4 0.2 0.0 1.1 3.6 0.3 0.4 2.4 9.8 6.2 0.3 1.9 0.8 9.6 0.0 3.4 0.0 0.0 0.8 0.7 0.6 0.0 0.6 0.6 0.3 4.5 0.4 0.0 0.0 0.1 1.7 2.1 5.8 1.1 0.4 0.0 0.5 0.0 1.8 0.3 0.0 0.1 1.8 4.1 0.0 0.4 2.6 19.3 0.4 1.8 1.0 0.0 3.7 0.0 0.0 0.1 7.0 1.5 18.0 1.8 2.7 12.5 0.5 1.3 2.1 0.0 0.9 3.3 0.6 1.9 8.4 0.4 0.7 1.2 0.3 1.6 3.5 ADAP2 CENTA2 ENSG00000184060 "ArfGAP with dual PH domains 2" Q9NPF8 17 30906344-30959322 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.2;Hofbauer cells: 195.8;Kupffer cells: 186.8;Macrophages: 97.2;monocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 22.4;intermediate monocyte: 34.3;myeloid DC: 12.6;non-classical monocyte: 43.5" "Group enriched" "Detected in many" 9 "dendritic cells: 12.6;monocytes: 43.5" "Cell line enhanced" "Detected in some" "EFO-21: 7.0;HAP1: 17.6;HEK 293: 11.0;RPMI-8226: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (4.00e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.25e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.38e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-2)" 11.3 8.9 6.6 15.3 7.6 3.9 4.6 6.7 8.5 2.9 9.1 6.5 5.7 3.2 2.9 3.1 3.3 9.2 4.4 6.2 8.0 5.1 11.0 9.8 9.8 12.1 9.6 1.9 3.1 9.1 1.9 19.7 10.4 2.4 8.0 1.3 3.1 3.1 1.8 6.7 5.6 9.8 8.6 22.5 4.3 2.0 14.7 4.6 3.2 6.4 6.7 9.0 2.2 12.9 0.1 1.7 0.2 0.4 0.4 0.5 4.5 0.1 0.0 0.3 0.1 0.7 0.7 1.0 7.0 0.1 0.2 0.1 17.6 0.2 0.3 0.4 11.0 0.0 1.0 2.0 2.9 0.4 1.9 1.1 4.4 0.9 0.6 0.2 0.0 0.0 0.2 1.8 0.6 3.6 0.1 0.3 0.1 0.4 0.1 0.3 0.0 22.9 2.4 2.3 0.3 0.1 0.3 0.2 0.1 1.5 3.8 2.9 0.0 0.4 1.1 0.8 0.1 0.8 0.5 1.0 0.4 0.4 0.0 0.2 22.4 0.0 0.0 34.3 0.0 3.0 0.1 0.1 12.6 2.1 0.1 0.1 1.7 0.0 43.5 0.4 0.4 6.6 6.6 7.6 6.7 8.5 6.2 8.0 12.1 9.6 10.4 8.6 14.7 12.9 5.4 3.2 5.2 2.6 8.6 2.0 0.5 0.5 2.2 0.8 0.7 2.4 1.5 1.5 0.9 0.0 2.1 23.5 0.2 3.1 0.0 0.3 0.6 1.7 0.6 7.8 0.0 0.4 1.1 1.4 86.2 1.9 0.0 1.2 3.8 0.4 4.6 1.6 195.8 0.0 1.4 0.6 0.0 186.8 13.1 0.5 0.9 97.2 0.0 40.3 88.2 0.6 2.1 2.0 1.3 0.9 0.9 0.4 2.6 0.9 0.3 8.3 2.2 2.8 39.5 1.2 26.5 0.9 0.9 1.0 6.5 26.4 1.6 0.2 0.3 0.6 ADCY2 "AC2, HBAC2, KIAA1060" ENSG00000078295 "Adenylate cyclase 2" Q08462 5 7396138-7830081 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 50.8;skeletal muscle: 68.3;tongue: 30.8" "Group enriched" "Detected in many" 5 "Astrocytes: 647.1;Excitatory neurons: 406.6;Horizontal cells: 201.9;Inhibitory neurons: 423.9;Oligodendrocyte precursor cells: 181.5" "Cancer enhanced" "Detected in some" "glioma: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 5.6;NTERA-2: 4.3;SK-MEL-30: 4.6;SuSa: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031482, HPA038015, HPA038483" Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB031482: AB_630838, HPA038015: AB_10673653, HPA038483: AB_10675799" "unprognostic (6.48e-2)" "unprognostic (2.60e-2)" "unprognostic (1.49e-1)" "unprognostic (5.65e-2)" "unprognostic (3.77e-1)" "unprognostic (4.03e-4)" "unprognostic (1.94e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (7.68e-2)" "unprognostic (1.09e-5)" "unprognostic (1.05e-1)" "unprognostic (7.33e-3)" "unprognostic (4.90e-2)" "unprognostic (3.92e-3)" 1.4 2.2 32.3 0.3 39.1 0.1 1.8 25.9 39.9 4.5 8.0 3.2 0.9 3.2 0.6 3.0 3.0 1.1 0.4 38.2 37.6 0.2 0.0 0.3 0.0 43.4 44.1 3.9 0.8 0.4 6.3 0.8 34.1 5.2 0.5 7.0 1.8 3.9 68.3 5.4 1.1 3.3 50.8 0.2 1.6 2.7 33.8 0.2 0.4 30.8 0.1 1.9 3.1 37.8 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 3.8 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.3 39.1 25.9 39.9 38.2 37.6 43.4 44.1 34.1 50.8 33.8 37.8 0.3 3.2 2.7 647.1 0.1 5.9 0.7 0.1 0.0 26.8 1.5 1.5 2.2 1.5 2.6 0.0 68.8 0.6 0.2 0.2 0.0 0.6 3.2 0.2 1.6 1.3 12.6 0.0 406.6 0.5 0.3 3.5 0.0 0.2 1.3 3.2 0.4 0.2 0.2 201.9 423.9 1.2 0.0 0.0 5.0 4.9 4.4 0.9 40.9 20.6 0.0 2.0 0.0 181.5 10.6 3.6 7.6 1.9 0.0 8.0 0.2 0.2 5.3 4.9 0.0 11.9 0.9 1.2 1.7 0.0 4.7 0.8 0.7 0.3 0.4 1.4 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.7;heart muscle: 105.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.5;Inhibitory neurons: 44.0;Oligodendrocytes: 89.7;Paneth cells: 59.6;Peritubular cells: 73.7;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 15.5;RPMI-8226: 2.7;RPTEC TERT1: 5.2" "Region enriched" "Detected in all" 5 "basal ganglia: 388.0" "Region enriched" "Detected in all" 6 "basal ganglia: 155.9" "HPA017730, HPA077682" Uncertain Enhanced "Intermediate filaments" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "HPA017730: AB_1844595, HPA077682: AB_2686851" "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favorable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" 18.9 3.3 25.5 4.9 97.7 0.0 10.6 13.9 43.9 9.8 0.0 35.1 5.2 14.7 5.7 18.8 12.7 10.0 105.2 25.8 15.9 12.8 3.3 4.1 2.3 20.5 18.3 13.2 7.5 0.8 14.3 6.1 17.4 19.8 5.6 4.5 4.0 21.5 2.7 2.6 13.0 18.2 10.8 6.5 21.2 8.2 34.4 1.3 1.9 5.8 3.0 23.2 7.8 30.1 0.0 0.6 1.3 0.1 0.1 0.1 0.3 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.2 2.3 0.5 0.6 0.0 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 15.5 0.0 0.0 0.8 0.0 0.1 0.0 0.3 2.7 5.2 0.5 1.8 1.6 0.0 0.5 0.1 1.7 0.0 0.1 0.0 0.1 1.2 0.1 0.2 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.5 97.7 13.9 43.9 25.8 15.9 20.5 18.3 17.4 10.8 34.4 30.1 0.3 0.0 0.0 8.1 0.1 0.3 0.1 0.2 0.0 21.8 0.4 5.8 75.5 8.6 0.0 7.3 0.0 1.4 0.0 2.6 0.0 15.9 0.9 1.5 7.1 1.8 0.0 0.0 34.0 6.9 4.0 5.2 0.0 4.0 0.0 4.6 3.9 0.1 0.3 0.0 44.0 0.3 0.0 0.0 0.3 3.0 20.5 0.1 0.0 6.5 1.0 1.0 0.0 19.1 89.7 0.4 59.6 73.7 0.0 0.1 0.3 0.8 0.0 2.2 65.7 0.6 21.4 0.8 6.3 0.2 0.9 12.4 0.2 1.0 2.0 0.1 ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843857-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 402.4;Rod photoreceptor cells: 624.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "CAB009794: AB_633663, HPA035873: AB_2674836, HPA035874: AB_2674837" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (5.40e-3)" "unprognostic (1.90e-1)" "unprognostic (2.66e-2)" "unprognostic (5.07e-3)" "unprognostic (1.68e-2)" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "prognostic favorable (3.94e-4)" "unprognostic (5.22e-2)" "prognostic favorable (1.29e-7)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-3)" 104.4 70.0 96.4 60.7 119.7 65.9 89.1 86.7 117.7 96.5 46.4 127.9 65.5 121.4 57.9 71.9 96.3 69.0 111.2 99.2 90.9 74.1 53.7 93.5 65.3 91.5 100.4 129.5 56.4 67.5 70.1 66.0 92.3 86.1 62.7 269.1 61.9 107.3 166.3 69.4 92.3 110.2 76.0 88.9 84.3 53.2 113.2 76.0 71.7 115.0 62.1 115.3 82.9 116.2 74.7 61.2 142.0 73.8 205.8 152.6 53.2 123.2 146.9 125.6 105.3 90.5 91.8 38.7 63.0 212.3 146.6 46.6 107.5 103.4 104.3 49.9 49.4 109.5 50.4 87.9 100.4 65.8 74.7 151.6 95.2 110.4 44.0 130.1 158.5 71.9 116.0 90.8 145.1 43.7 203.7 91.6 80.0 67.9 85.7 89.1 78.6 45.7 91.2 162.2 84.8 110.0 88.9 35.8 76.9 107.0 84.2 61.7 193.4 102.1 52.4 84.7 103.0 72.5 63.3 48.9 98.2 80.4 100.9 20.1 7.6 35.5 19.1 7.3 17.6 23.8 10.6 16.3 12.0 31.2 9.8 11.8 10.5 27.2 11.4 25.4 14.8 16.0 96.4 119.7 86.7 117.7 99.2 90.9 91.5 100.4 92.3 76.0 113.2 116.2 89.3 70.5 45.4 141.3 66.5 26.9 29.8 33.0 27.9 99.5 41.2 41.5 78.0 40.0 46.3 60.7 402.4 35.5 84.0 51.3 15.6 37.3 48.5 43.9 61.2 89.4 57.7 57.9 85.7 45.8 32.5 72.9 39.8 58.1 37.3 53.0 84.3 41.8 41.8 111.0 83.2 39.3 28.5 51.6 42.2 35.9 77.6 47.4 35.6 72.1 58.3 233.8 120.5 68.9 178.6 53.2 39.4 121.9 49.7 35.8 48.6 44.6 40.4 624.3 98.6 58.4 73.1 45.3 33.2 30.5 36.7 36.5 55.6 80.7 45.1 33.0 ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 449.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.2;ASC TERT1: 292.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 260000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB009797: AB_2223583, HPA035696: AB_2674740" "unprognostic (2.66e-1)" "unprognostic (2.63e-2)" "unprognostic (1.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-2)" "unprognostic (1.57e-3)" "unprognostic (6.42e-2)" "unprognostic (5.73e-2)" "unprognostic (2.37e-2)" "unprognostic (7.58e-2)" "unprognostic (9.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.36e-1)" "unprognostic (4.03e-1)" "unprognostic (3.68e-2)" "unprognostic (5.92e-2)" 57.7 21.7 105.6 38.8 97.2 37.5 89.4 88.6 129.3 57.6 65.9 58.2 71.9 24.9 62.4 39.0 47.6 72.0 59.9 113.3 108.1 102.7 27.8 38.4 70.9 107.3 94.8 46.4 67.9 18.8 25.3 36.6 102.0 32.7 66.0 99.4 59.1 31.8 9.6 33.6 85.4 23.9 105.2 40.0 63.7 51.5 95.6 87.4 87.7 25.6 65.4 42.3 40.1 122.4 29.2 6.0 41.7 19.8 313.2 292.1 17.7 41.2 110.9 25.4 49.9 60.3 90.6 89.9 45.2 63.9 26.4 10.0 37.3 27.1 39.5 9.0 46.5 8.8 28.5 45.9 35.5 30.5 66.0 142.5 12.9 63.3 2.6 96.4 37.8 109.9 23.5 48.7 46.7 0.8 32.3 31.0 25.8 69.2 15.3 27.7 58.2 4.8 65.7 14.2 6.1 67.9 27.6 8.9 66.5 62.2 10.7 11.4 9.5 16.0 42.0 33.5 9.1 68.9 31.5 82.7 47.8 16.2 27.7 139.5 29.6 98.0 68.8 26.5 55.7 51.4 72.9 59.1 24.8 42.9 83.2 67.6 47.1 73.4 32.6 16.3 73.3 94.9 105.6 97.2 88.6 129.3 113.3 108.1 107.3 94.8 102.0 105.2 95.6 122.4 67.3 22.4 52.9 449.2 110.6 55.7 35.9 77.4 38.7 26.8 56.0 34.4 128.2 74.4 85.5 36.8 60.5 55.6 112.7 125.2 60.7 27.2 51.4 70.3 76.0 77.7 102.4 32.6 83.4 61.1 12.1 182.4 100.9 56.0 26.0 18.8 126.7 12.2 25.7 116.1 141.1 71.6 48.8 88.5 41.1 25.7 226.5 66.3 58.7 70.3 65.3 339.0 151.4 236.8 279.6 59.8 167.1 251.3 68.4 38.4 135.2 162.2 151.9 121.7 65.7 27.6 36.2 122.7 62.1 53.2 50.6 22.3 111.5 30.9 166.7 98.6 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1227.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Endometrial stromal cells: 5.4;Fibroblasts: 5.3;Gastric mucus-secreting cells: 9.2;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.0;BEWO: 7.3;HeLa: 5.9;NTERA-2: 6.4;RPMI-8226: 4.5;SH-SY5Y: 6.6;U-2197: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" 3.9 0.3 0.1 0.9 0.1 0.0 2.0 0.0 1.1 1.0 0.0 0.5 0.5 1.0 1227.7 0.5 16.5 1.6 1.3 0.8 0.7 0.4 0.7 1.3 5.0 0.4 1.5 0.2 1.2 163.4 1.1 0.5 0.6 2.1 0.4 0.9 8.5 3.6 0.2 0.4 1.1 0.4 0.1 2.4 9.0 1.9 0.3 6.6 1.6 1.1 3.7 0.8 1.0 0.2 0.2 6.0 0.0 0.0 0.1 0.9 7.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.4 0.0 5.9 0.2 0.8 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 2.2 6.4 0.0 2.0 0.0 0.0 4.5 0.0 1.2 2.2 6.6 1.5 0.1 0.0 1.1 0.1 0.1 0.1 0.2 0.4 14.6 2.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.8 0.7 0.4 1.5 0.6 0.1 0.3 0.2 0.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.0 0.6 1.2 1.1 1.0 7.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.1 1.1 5.4 0.6 0.0 0.0 4.4 0.2 0.3 5.3 9.2 3.2 0.0 0.2 1.4 0.4 0.0 3.3 5.0 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.0 4.7 0.0 4.8 0.0 10.1 7.0 3.1 0.0 1.5 0.0 3.4 0.0 0.1 2.2 0.7 0.0 1.6 0.6 0.1 1.4 0.1 0.0 0.0 0.3 0.3 0.0 0.3 ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 584.1;Excitatory neurons: 696.1;Inhibitory neurons: 737.4;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 592.1" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.8;EFO-21: 10.8;HEK 293: 6.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" 7.1 6.2 25.1 1.1 25.7 0.0 2.5 14.0 30.7 5.5 0.0 4.0 2.5 3.9 1.8 1.0 2.4 1.6 2.6 30.4 25.0 1.6 0.4 2.6 0.4 15.3 24.6 1.1 0.3 6.7 0.9 1.2 15.9 1.3 3.9 10.0 0.6 4.2 0.7 3.0 3.6 3.0 12.5 0.3 3.2 4.1 32.3 0.4 0.7 0.3 0.1 1.6 3.4 15.7 0.0 0.1 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 3.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 1.0 0.0 4.0 0.5 0.1 0.1 0.0 4.8 0.2 0.0 6.3 0.3 0.0 0.0 0.0 7.6 0.1 3.2 0.0 0.2 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 25.7 14.0 30.7 30.4 25.0 15.3 24.6 15.9 12.5 32.3 15.7 0.4 0.0 0.0 584.1 0.0 0.0 0.0 0.0 0.6 12.4 4.9 1.8 3.3 0.0 0.0 0.0 4.2 1.0 0.0 0.0 9.8 0.0 46.4 1.3 17.7 1.9 0.0 0.0 696.1 0.0 1.3 3.3 0.0 0.4 0.0 0.4 2.5 0.2 0.1 1.7 737.4 0.0 0.0 0.0 0.0 33.2 0.0 0.5 0.0 70.3 0.0 31.3 0.0 1300.8 592.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.4 6.6 0.3 18.5 0.9 3.5 1.2 0.0 2.2 0.2 0.1 0.0 0.1 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 306 "liver: 2739.1" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 200.9" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 8.2" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" 7.2 1.6 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 8.9 0.3 0.5 0.1 0.5 6.6 0.3 0.0 0.0 0.7 2739.1 0.8 0.0 0.1 0.1 0.1 1.1 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.8 0.0 0.1 0.3 0.4 0.3 0.0 0.0 0.1 1.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.1 0.3 0.0 10.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 8.6 200.9 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 4153.7" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 6574.3" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 1501.5 140.2 2.2 36.4 3.4 0.1 924.6 1.9 9.0 41.0 13.5 202.2 38.5 161.4 74.8 105.8 385.0 145.1 215.3 2.0 1.9 66.7 5858.7 373.2 25.8 4.7 2.2 117.7 49.1 7.8 24.2 6.8 3.2 26.7 114.7 0.1 67.9 26.7 66.6 159.2 237.1 73.4 4.4 72.7 141.1 2.8 2.2 19.8 94.5 228.2 16.0 287.9 118.7 2.4 0.0 0.0 0.0 0.0 6574.3 956.7 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.0 0.0 0.5 1.4 0.0 0.1 0.0 1.1 0.1 0.0 26.9 3.0 0.0 216.8 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.2 0.3 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 1.9 9.0 2.0 1.9 4.7 2.2 3.2 4.4 2.2 2.4 29.0 0.0 3.4 0.0 8.1 22.3 0.5 0.1 6.8 0.1 1.1 2.5 12.2 110.1 2.3 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.6 0.1 0.9 14.7 0.0 115.0 0.0 0.0 0.1 633.1 11.2 0.0 1.3 0.0 96.8 4153.7 0.1 0.0 0.0 0.0 0.0 98.8 25.4 0.6 55.3 3.5 28.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.7 0.0 0.1 0.2 0.1 6.6 15.0 47.9 0.0 0.1 10.4 13.1 0.1 8.9 0.1 0.0 0.2 ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "adipose tissue: 898.8;breast: 248.9" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 672 "ASC diff: 312.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" NA NA 8360000000 910000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB046467: AB_1078104, HPA051767: AB_2681598" "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" 898.8 8.9 0.1 2.4 0.1 0.2 248.9 0.2 0.1 0.0 0.0 7.7 0.1 0.1 0.0 1.2 0.1 7.6 6.5 0.0 0.0 0.8 0.1 0.1 1.3 0.1 0.0 0.0 6.2 0.1 0.1 0.0 0.1 0.3 6.1 0.1 18.8 0.0 2.3 6.6 8.5 1.2 0.0 0.0 3.9 0.1 0.1 2.2 2.9 20.2 0.0 2.4 0.9 0.3 0.0 0.0 0.0 0.1 312.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADIPOR2 "ACDCR2, PAQR2" ENSG00000006831 "Adiponectin receptor 2" Q86V24 12 1688574-1788674 "Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 321.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043737 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA043737: AB_10964205" "unprognostic (1.52e-1)" "unprognostic (2.11e-1)" "unprognostic (2.44e-1)" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (1.34e-1)" "unprognostic (5.33e-2)" "unprognostic (7.66e-3)" "unprognostic (4.86e-2)" "unprognostic (1.61e-1)" "unprognostic (5.34e-3)" "unprognostic (2.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.15e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (5.85e-2)" 55.1 72.3 36.6 10.6 49.8 9.6 44.2 46.4 48.7 25.8 28.3 32.2 22.2 24.4 8.1 45.2 23.3 9.7 33.3 35.3 40.6 22.4 79.6 44.6 9.8 50.9 46.9 25.1 31.1 16.9 26.1 13.0 49.5 20.7 17.7 13.1 22.2 11.9 42.9 31.9 32.7 12.0 41.6 19.9 44.7 27.7 44.5 12.8 28.0 19.9 12.6 21.4 29.3 67.0 34.3 28.0 23.1 21.4 21.4 25.6 30.9 24.6 28.4 31.5 44.5 42.1 51.6 24.1 7.8 23.0 56.7 26.1 34.7 35.8 44.9 62.7 28.7 47.3 22.7 30.3 21.2 36.1 29.3 22.6 35.5 39.8 45.6 28.7 23.1 25.8 31.7 50.9 23.7 48.8 23.6 32.8 46.3 28.4 14.8 19.5 43.7 18.3 31.4 19.9 6.9 16.4 22.7 43.8 51.5 39.7 24.6 46.5 23.2 17.8 37.5 28.6 36.2 12.3 16.5 39.5 21.7 32.3 24.7 0.7 0.7 1.8 0.9 0.7 0.7 0.5 0.5 0.8 0.5 0.5 0.6 0.7 0.9 0.6 0.6 0.9 0.7 0.3 36.6 49.8 46.4 48.7 35.3 40.6 50.9 46.9 49.5 41.6 44.5 67.0 81.5 12.8 32.4 39.2 21.8 23.7 25.0 26.6 22.8 11.3 29.9 20.3 22.3 31.5 36.6 14.7 18.8 13.9 32.4 91.4 11.7 22.6 56.3 17.8 15.4 41.1 37.5 38.1 35.7 31.4 42.2 21.1 61.7 30.2 36.3 28.8 28.9 113.4 18.2 18.5 41.3 49.0 32.6 27.3 18.9 77.0 15.8 32.6 26.6 124.6 27.0 32.5 27.8 32.2 321.0 39.6 49.4 22.6 30.2 27.8 41.5 10.8 21.7 16.0 6.6 21.3 25.7 45.0 42.2 29.7 34.4 29.3 26.1 39.6 33.5 29.8 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 ADPRH ARH1 ENSG00000144843 "ADP-ribosylarginine hydrolase" P54922 3 119579268-119589945 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 14.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 23.9;HEL: 17.1;HMC-1: 18.5;Karpas-707: 25.3;U-266/70: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001701, HPA036961" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Nuclear membrane" Nucleoplasm "CAB001701: , HPA036961: AB_2675405" "prognostic favorable (2.42e-4)" "unprognostic (2.29e-1)" "unprognostic (4.77e-1)" "unprognostic (2.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.06e-2)" "unprognostic (2.63e-1)" "unprognostic (4.24e-2)" "unprognostic (3.31e-3)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (6.04e-2)" "unprognostic (2.60e-3)" "unprognostic (8.87e-2)" "unprognostic (2.03e-1)" "unprognostic (4.35e-2)" 10.6 6.2 3.0 7.3 3.3 3.4 7.9 3.3 4.2 6.9 9.2 5.5 2.3 6.0 4.9 4.0 4.2 6.9 8.5 2.9 3.5 4.9 3.1 13.5 11.0 4.6 3.4 1.9 6.7 8.0 2.0 11.3 4.4 6.1 4.1 6.6 5.1 9.3 11.8 2.6 5.4 9.2 4.2 11.9 3.9 2.4 4.6 5.9 5.8 9.9 13.0 6.5 3.4 4.9 2.4 3.0 0.7 0.0 2.4 2.7 0.0 2.1 0.4 1.8 2.3 0.9 2.0 0.6 0.9 3.2 0.1 0.2 2.0 0.0 1.7 23.9 0.2 17.1 0.4 0.0 3.9 0.1 18.5 4.0 0.1 0.9 0.1 0.8 7.3 0.0 1.6 25.3 11.0 0.7 0.0 4.1 6.9 0.2 5.8 0.0 8.2 1.1 1.0 0.9 0.5 0.1 0.0 0.1 6.4 1.0 4.4 10.6 6.0 0.0 1.1 4.6 0.4 24.5 5.8 0.1 3.0 0.0 4.6 13.9 18.7 19.1 0.8 17.2 0.8 11.0 1.9 1.7 11.2 6.8 0.2 0.7 0.6 5.3 13.9 9.8 14.3 7.5 3.0 3.3 3.3 4.2 2.9 3.5 4.6 3.4 4.4 4.2 4.6 4.9 12.6 9.6 8.6 0.3 5.0 0.8 0.7 0.4 0.0 0.5 1.5 1.9 4.7 2.8 2.7 3.7 4.2 5.8 5.0 0.3 1.9 3.6 0.7 0.2 0.9 9.9 0.0 2.7 0.1 3.2 3.8 2.1 2.6 0.5 10.8 2.5 7.1 1.6 9.4 0.0 0.2 0.2 2.0 12.2 11.1 0.5 0.3 14.8 1.8 4.7 10.2 0.8 4.1 0.0 0.6 2.1 0.5 3.0 3.9 0.7 0.0 1.3 2.1 4.3 0.0 3.6 3.9 0.4 0.6 0.1 0.9 11.8 1.2 0.7 0.2 0.2 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159973012 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 36.9;liver: 11.4;lymphoid tissue: 11.6" "Group enriched" "Detected in some" 7 "Excitatory neurons: 41.5;Inhibitory neurons: 32.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 36.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.9;HaCaT: 5.8;TIME: 9.8;U-2 OS: 7.9;U-251 MG: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA074416: AB_2686688" "unprognostic (4.93e-3)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.00e-5)" "prognostic unfavorable (6.98e-4)" "unprognostic (4.08e-3)" "unprognostic (1.67e-3)" "unprognostic (1.68e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.28e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.40e-6)" "unprognostic (5.24e-4)" "unprognostic (2.54e-1)" "prognostic favorable (3.19e-5)" "unprognostic (1.59e-2)" 4.2 1.8 3.4 0.3 16.1 0.0 1.9 0.0 7.9 0.4 0.0 0.7 0.4 0.9 1.4 0.3 3.0 0.5 2.0 6.0 3.4 3.9 11.4 4.0 1.2 0.0 36.9 2.9 0.4 0.5 0.6 0.3 6.3 0.6 0.3 0.5 0.3 0.7 0.7 0.9 1.4 0.4 0.0 11.6 0.7 0.2 4.5 0.1 1.5 0.7 0.3 0.4 0.6 5.2 0.4 4.5 0.3 0.0 1.9 0.8 0.1 0.5 0.1 0.5 0.2 0.0 3.8 0.0 11.9 3.4 4.4 5.8 0.0 0.5 0.3 0.0 0.2 0.0 1.7 0.0 4.1 0.0 0.0 2.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.7 0.0 3.8 0.0 0.4 0.0 0.0 0.3 0.3 1.7 0.1 0.0 9.8 0.1 7.9 0.0 6.6 0.0 0.0 0.0 2.9 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 16.1 0.0 7.9 6.0 3.4 0.0 36.9 6.3 0.0 4.5 5.2 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADRB1 ADRB1R ENSG00000043591 "Adrenoceptor beta 1" P08588 10 114043866-114046904 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.7;lung: 13.1;placenta: 29.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 85.7;Cytotrophoblasts: 84.5;Sertoli cells: 52.6;Syncytiotrophoblasts: 38.4" "Cancer enriched" "Detected in many" 10 "prostate cancer: 12.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.1;PC-3: 2.6;THP-1: 4.5;TIME: 5.8;U-937: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067972 Enhanced NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA067972: AB_2685936" "unprognostic (1.45e-3)" "unprognostic (1.18e-3)" "unprognostic (1.44e-1)" "unprognostic (4.92e-2)" "unprognostic (3.22e-1)" "unprognostic (8.88e-2)" "unprognostic (9.28e-2)" "unprognostic (3.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-2)" "unprognostic (2.77e-4)" "unprognostic (1.33e-1)" "unprognostic (7.80e-3)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" 4.0 0.2 5.5 0.3 10.3 0.5 2.3 0.7 12.0 0.1 0.2 3.1 0.9 0.1 0.1 0.9 0.1 0.1 23.7 6.8 3.3 1.1 1.4 13.1 0.2 1.8 3.1 0.0 1.3 0.8 0.8 29.1 2.4 4.4 0.6 2.1 5.4 0.1 2.3 0.4 1.9 0.1 0.9 1.5 0.7 0.5 5.0 0.1 0.6 0.0 0.3 0.7 0.1 7.8 1.4 0.8 0.1 0.8 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.3 1.0 0.2 0.2 0.0 0.4 0.3 0.1 0.1 0.1 7.1 0.4 0.3 0.1 0.1 0.0 0.2 0.4 0.0 0.7 0.0 1.3 0.1 0.1 1.0 0.0 0.1 0.1 0.8 1.1 0.9 0.3 0.2 2.6 0.2 0.2 0.1 0.0 1.1 0.1 0.2 0.0 0.5 0.0 0.3 0.2 4.5 5.8 0.2 0.1 0.1 0.1 0.0 0.0 0.3 0.0 3.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 10.3 0.7 12.0 6.8 3.3 1.8 3.1 2.4 0.9 5.0 7.8 1.1 19.2 7.8 15.0 0.5 1.0 3.9 0.8 1.2 21.8 1.0 0.5 85.7 2.8 9.8 0.0 0.0 84.5 3.0 0.1 1.9 0.1 0.1 0.4 0.6 11.3 0.0 0.0 12.8 0.2 5.2 5.3 0.0 0.3 0.0 0.0 0.4 0.2 4.4 13.5 2.5 3.3 2.0 2.2 1.6 0.2 0.0 2.8 1.8 7.5 0.6 0.7 3.1 1.0 0.3 0.1 1.4 0.4 1.2 6.1 0.8 0.0 12.1 1.7 52.6 0.4 8.2 0.5 0.2 0.1 0.0 38.4 4.8 0.0 0.6 3.9 ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;ovary: 11.7" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.8;Hofbauer cells: 1.1;Langerhans cells: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "medulla oblongata: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Fibroblasts - ECM organization" "HPA061969: AB_2732674" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" 0.3 0.0 1.2 0.4 1.1 0.2 0.3 0.5 0.9 0.4 1.5 2.1 0.2 0.7 1.1 0.1 4.1 1.7 0.0 0.9 0.7 0.0 0.0 0.1 0.1 8.1 2.7 11.7 0.0 0.0 0.0 2.9 3.1 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.0 4.6 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.5 0.9 0.9 0.7 8.1 2.7 3.1 0.4 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGPAT2 "BSCL, LPAAT-beta" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687457 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 369.3;liver: 445.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 688.9;Late spermatids: 387.3;Paneth cells: 670.7;Proximal enterocytes: 1298.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 186.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019544 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" 369.3 38.3 11.4 11.8 9.3 34.2 259.9 8.8 15.9 32.1 13.5 83.2 111.4 26.4 9.6 85.6 29.7 15.7 84.9 9.4 12.6 80.2 445.0 60.9 9.2 11.8 12.3 17.7 129.6 18.4 41.5 8.0 11.3 34.3 12.2 0.9 48.1 12.8 37.4 51.1 119.4 6.7 11.4 39.2 52.0 24.1 13.9 5.5 46.9 10.0 5.3 35.5 36.6 9.6 55.0 75.2 8.9 41.4 63.3 19.8 37.3 35.5 28.5 24.1 18.5 86.0 105.7 17.8 77.8 21.0 38.6 145.1 12.7 22.2 2.8 186.9 57.3 26.5 30.3 19.2 42.6 28.1 62.1 19.0 30.9 20.9 11.0 20.9 12.5 23.6 32.7 2.9 10.4 98.5 1.9 87.4 22.5 101.0 135.0 41.0 31.3 100.3 28.5 33.9 19.5 31.4 45.8 47.6 60.3 6.8 30.6 109.3 24.7 31.5 32.1 10.4 23.0 4.4 0.4 11.8 0.4 59.7 32.1 20.1 88.8 111.8 6.8 83.5 6.5 12.8 5.8 7.9 47.8 22.7 4.6 5.5 61.1 7.2 75.7 65.6 8.1 35.2 11.4 9.3 8.8 15.9 9.4 12.6 11.8 12.3 11.3 11.4 13.9 9.6 25.9 16.0 64.4 0.7 20.2 45.2 60.0 64.0 22.8 3.5 23.4 22.4 39.6 87.2 45.3 73.5 0.0 7.3 30.8 688.9 54.8 155.2 136.4 50.4 17.4 27.9 35.8 8.0 1.9 219.5 37.1 30.1 81.6 63.8 13.4 31.4 31.1 228.0 131.2 40.4 2.6 197.3 126.1 53.4 57.4 387.3 26.8 57.6 136.9 4.7 48.8 14.6 23.7 0.0 0.3 169.5 670.7 20.3 13.4 93.5 1298.3 41.9 46.3 3.8 46.0 15.3 29.8 1.8 27.2 47.5 81.3 6.8 26.6 16.4 207.7 196.2 AGPAT3 "LPAAT-gamma, LPAAT3" ENSG00000160216 "1-acylglycerol-3-phosphate O-acyltransferase 3" Q9NRZ7 21 43865223-43987592 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 183.5;Early spermatids: 219.0;Late spermatids: 219.3;Rod photoreceptor cells: 184.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (2.36e-2)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.50e-2)" "unprognostic (4.56e-3)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (4.88e-2)" "unprognostic (9.72e-3)" "unprognostic (2.14e-1)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (2.84e-1)" "prognostic favorable (2.29e-4)" "unprognostic (1.50e-2)" "unprognostic (8.91e-2)" "unprognostic (1.80e-1)" "unprognostic (4.60e-2)" 20.9 20.9 41.5 19.2 47.1 11.1 15.1 42.3 34.9 11.7 14.8 22.0 44.7 10.3 12.6 25.7 12.3 13.8 27.8 38.4 36.0 53.4 53.2 18.8 16.4 52.1 41.8 10.4 21.3 24.6 14.7 12.2 39.2 13.8 11.9 61.9 30.5 11.6 62.3 24.3 52.4 8.7 47.8 19.1 18.0 26.4 48.1 15.4 21.4 50.2 10.3 15.4 15.0 48.2 73.0 40.0 10.0 27.5 17.8 20.4 7.7 32.6 40.6 40.8 25.1 40.3 51.4 24.5 24.3 39.3 38.4 27.8 17.3 36.5 11.8 117.2 45.8 10.8 24.4 54.8 33.6 39.6 23.5 25.1 30.4 36.1 15.0 35.1 31.2 8.0 61.4 39.1 15.0 31.2 0.4 22.9 4.7 28.2 28.5 40.6 11.3 65.9 29.7 70.2 34.0 24.7 40.0 45.0 29.9 3.9 31.3 42.9 46.6 25.9 0.3 39.1 34.0 31.0 50.3 15.3 33.3 78.3 23.9 0.0 3.3 2.2 1.1 7.4 1.2 0.9 1.6 1.7 3.8 1.1 1.3 1.5 0.9 0.6 9.6 0.9 3.0 1.8 41.5 47.1 42.3 34.9 38.4 36.0 52.1 41.8 39.2 47.8 48.1 48.2 17.0 12.8 25.4 33.0 7.0 8.0 9.3 14.5 7.4 40.3 19.8 12.3 33.4 25.8 21.0 25.8 183.5 15.9 10.8 45.1 9.8 25.7 219.0 17.7 16.6 16.3 13.8 12.8 34.3 29.5 1.1 10.4 19.9 18.5 5.1 24.6 15.4 68.7 19.0 65.6 37.9 19.7 12.2 32.6 27.3 219.3 7.8 25.7 1.8 17.8 38.5 34.1 9.2 19.1 28.7 26.8 18.8 5.7 11.8 18.6 60.5 52.6 31.0 184.0 6.6 14.9 24.4 7.0 2.4 17.4 11.1 12.0 14.4 22.0 22.5 15.7 AGR2 "AG2, HAG-2, PDIA17, XAG-2" ENSG00000106541 "Anterior gradient 2, protein disulphide isomerase family member" O95994 7 16791811-16833433 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 638.7;intestine: 1224.0;stomach 1: 1402.3" "Cell type enhanced" "Detected in many" "Club cells: 1515.8;Distal enterocytes: 1026.4;Gastric mucus-secreting cells: 2605.5;Intestinal goblet cells: 3710.4;Paneth cells: 1101.6;Undifferentiated cells: 1543.1;Urothelial cells: 1017.8" "Cancer enhanced" "Detected in many" "stomach cancer: 475.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 15 "OE19: 20084.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007912 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 38000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA007912: AB_1844879" "unprognostic (6.19e-2)" "unprognostic (1.91e-1)" "unprognostic (9.05e-2)" "unprognostic (2.59e-2)" "unprognostic (2.23e-1)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.49e-2)" "unprognostic (1.84e-1)" "unprognostic (1.08e-2)" "unprognostic (3.24e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (8.79e-5)" "unprognostic (6.98e-2)" "unprognostic (2.38e-1)" "unprognostic (2.38e-1)" "unprognostic (3.22e-3)" 2.1 0.7 0.0 66.6 0.0 0.0 72.3 0.2 0.5 638.7 0.0 768.1 486.0 14.1 389.1 16.2 306.4 275.8 0.2 0.1 0.0 11.2 0.9 50.7 0.6 0.0 0.1 0.3 22.1 0.1 31.4 1.6 0.0 227.3 1224.0 0.0 475.3 181.0 0.2 2.5 379.2 45.2 0.0 0.9 1402.3 0.9 0.0 1.7 7.4 0.1 7.2 160.8 4.0 0.1 0.3 265.5 0.0 0.3 0.0 0.1 2.6 0.0 0.0 0.0 0.0 43.5 39.7 0.0 0.2 0.0 6.6 25.2 0.0 34.5 0.2 0.0 0.0 0.0 0.9 3.8 0.0 0.0 1.0 0.0 88.5 0.0 11.4 0.4 0.4 0.3 0.0 0.0 0.2 44.7 1.3 1.8 0.8 20084.0 154.2 1.0 0.0 5.2 631.3 371.6 1.7 2.1 0.0 98.8 0.0 1.0 1319.9 0.0 0.0 0.7 1.2 0.9 0.2 1.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 51.3 293.1 0.0 19.0 2.8 127.1 539.8 0.6 0.0 169.3 137.4 0.2 268.8 1515.8 80.9 0.0 6.0 0.4 1026.4 0.0 74.1 4.6 301.9 33.9 4.8 522.1 0.0 0.1 835.1 4.5 6.0 2605.5 365.3 43.9 0.0 0.0 1.7 240.8 0.0 0.1 3710.4 386.6 0.8 0.3 0.4 0.3 6.5 3.6 0.0 1.0 0.0 0.0 0.0 0.0 303.1 1101.6 0.0 2.6 426.9 517.9 0.2 781.0 0.0 0.0 0.0 76.9 0.4 0.2 5.3 2.8 3.3 13.1 0.0 1543.1 1017.8 AGR3 "BCMP11, hAG-3, HAG3, PDIA18" ENSG00000173467 "Anterior gradient 3, protein disulphide isomerase family member" Q8TD06 7 16859412-16881987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 225.2;intestine: 237.6;lung: 152.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 861.1;Intestinal goblet cells: 701.9;Paneth cells: 744.5;Proximal enterocytes: 1051.2;Respiratory ciliated cells: 1771.2;Undifferentiated cells: 495.4" "Cancer enhanced" "Detected in many" "breast cancer: 104.5" "Region enhanced" "Detected in some" "midbrain: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "OE19: 109.8;T-47d: 339.3" "Region enriched" "Detected in some" 5 "olfactory bulb: 4.6" HPA053942 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA 67000 "Cluster 9: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum" Vesicles "HPA053942: AB_2682317" "unprognostic (2.18e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (9.59e-2)" "unprognostic (3.32e-3)" "unprognostic (3.08e-2)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (6.66e-2)" "unprognostic (1.57e-1)" 0.6 0.1 0.0 11.0 0.0 0.0 69.6 0.0 0.2 25.0 0.1 219.9 167.2 8.7 0.0 1.5 225.2 48.3 0.1 0.1 0.4 2.5 0.3 152.7 0.2 2.0 3.4 0.3 10.7 0.0 21.2 0.8 1.0 4.8 214.9 0.0 30.9 0.8 0.0 1.5 237.6 8.7 0.7 0.3 99.9 0.2 0.2 0.0 7.3 0.0 0.8 27.6 0.2 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 109.8 0.0 0.0 0.0 2.3 8.1 0.0 1.3 0.4 0.0 0.6 0.0 0.0 339.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 2.0 3.4 1.0 0.7 0.2 0.5 0.7 333.3 408.1 0.3 1.4 2.7 12.5 108.5 0.0 0.0 105.1 51.9 0.1 31.5 319.9 29.5 0.0 3.4 0.7 380.0 1.9 30.4 0.0 861.1 7.4 1.9 112.7 0.0 0.2 71.4 3.3 5.3 71.4 39.2 20.8 0.0 0.0 0.0 0.5 0.0 0.2 701.9 134.3 0.0 0.3 0.0 0.3 2.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 16.6 744.5 0.0 0.4 7.1 1051.2 0.0 1771.2 0.0 0.0 0.0 27.9 0.0 0.1 0.0 9.8 2.2 4.1 0.0 495.4 117.9 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.6;placenta: 141.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 53.1;Hepatocytes: 30.9;Leydig cells: 145.1;Sertoli cells: 144.7;Smooth muscle cells: 71.2" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enhanced" "Detected in some" "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 176.8;ASC TERT1: 24.4;BJ hTERT+ SV40 Large T+: 34.8;HBF TERT88: 53.9;HSkMC: 32.2" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 65.9 38.2 0.3 1.8 0.7 0.0 39.9 0.2 0.4 3.4 0.4 21.1 0.8 3.5 2.7 2.8 9.8 6.2 10.9 0.4 1.4 18.4 96.6 10.4 0.7 2.1 8.1 3.8 3.5 2.8 3.8 141.6 0.9 5.3 4.4 0.9 4.7 4.2 11.6 15.8 4.3 4.6 0.2 9.1 6.5 2.2 0.7 3.0 14.2 13.8 0.2 14.6 6.1 0.2 0.0 1.0 0.8 0.0 176.8 24.4 0.0 0.2 3.9 34.8 20.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.2 0.0 3.4 1.8 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.2 0.4 0.4 1.4 2.1 8.1 0.9 0.2 0.7 0.2 20.5 0.0 0.6 0.0 0.0 3.4 0.2 0.0 0.0 0.0 1.3 0.9 6.3 2.8 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.1 0.8 0.0 0.3 3.8 23.5 0.0 0.1 7.6 0.3 53.1 0.5 0.0 0.0 0.0 17.5 30.9 0.7 0.0 0.0 0.2 0.0 0.3 3.5 1.7 145.1 0.5 1.8 2.8 0.0 5.7 0.0 0.0 0.1 0.5 0.0 7.5 0.4 1.1 0.0 0.1 0.0 0.1 144.7 7.6 71.2 0.0 1.8 0.3 1.7 0.3 0.5 0.3 0.0 0.1 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.3;Basal respiratory cells: 83.8;Horizontal cells: 60.6;Ionocytes: 61.1;Pancreatic endocrine cells: 68.2;Respiratory ciliated cells: 66.8;Squamous epithelial cells: 63.7;Suprabasal keratinocytes: 164.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 135.1;HBEC3-KT: 124.9;hTCEpi: 308.7;hTERT-HME1: 130.3;TIME: 138.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" 30.4 2.3 9.8 2.4 9.9 0.0 16.4 9.3 15.9 84.5 4.6 105.3 1.4 64.3 2.9 114.1 29.2 5.1 4.5 9.7 16.0 3.5 6.2 5.1 0.1 38.1 15.3 3.5 1.6 0.7 3.4 1.8 40.8 18.6 8.6 19.0 24.0 28.6 3.6 305.9 20.2 31.6 12.4 0.9 25.2 7.7 18.1 0.4 2.8 4.5 4.7 49.4 86.6 18.5 2.9 107.6 0.1 6.0 120.0 135.1 0.2 10.5 22.3 3.8 1.9 0.3 38.9 0.1 14.5 82.9 85.3 62.9 0.3 124.9 1.7 0.0 0.4 0.0 67.5 0.5 11.0 0.0 3.8 17.6 308.7 12.1 130.3 52.3 54.7 0.0 0.0 0.2 62.8 8.0 0.0 0.0 0.3 9.5 42.9 0.3 5.7 0.1 84.4 0.0 0.6 0.6 46.2 0.1 2.3 2.8 6.0 0.0 138.4 29.3 17.9 33.8 9.9 0.0 0.0 0.0 88.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.8 9.9 9.3 15.9 9.7 16.0 38.1 15.3 40.8 12.4 18.1 18.5 3.8 12.8 1.1 0.3 0.0 114.3 4.9 83.8 13.1 8.9 2.2 1.3 1.5 0.0 38.2 1.8 2.1 0.2 0.3 0.4 0.0 11.9 24.2 16.0 10.5 13.0 0.0 0.0 8.2 8.7 0.5 31.9 0.0 18.9 17.1 0.1 3.6 2.1 1.0 60.6 5.1 0.0 61.1 0.3 12.7 3.1 0.6 0.7 32.0 3.7 0.0 3.2 0.0 1.5 3.3 68.2 0.0 0.4 0.0 4.5 0.0 0.3 66.8 13.9 0.0 13.1 8.6 0.4 4.3 63.7 164.7 0.1 0.9 0.1 0.2 6.2 AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 22 "Hofbauer cells: 1777.1;Kupffer cells: 2140.2;Langerhans cells: 1359.1;Macrophages: 1494.0;monocytes: 1022.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Group enriched" "Detected in some" 4 "HEL: 204.6;HMC-1: 329.6;NB-4: 264.7;THP-1: 184.2;U-937: 114.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" 79.6 46.6 24.9 182.3 25.5 235.0 47.2 26.6 33.0 29.3 32.2 48.3 36.4 17.1 12.1 18.7 19.7 61.3 21.1 25.0 31.3 74.3 81.2 99.3 116.8 45.1 36.4 14.4 12.4 12.9 17.3 109.5 36.8 22.3 57.2 3.9 20.3 24.0 6.1 11.7 44.5 74.7 34.3 346.6 22.2 8.7 32.1 69.1 13.8 16.6 57.1 95.3 13.5 42.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 204.6 0.0 0.0 0.0 30.0 329.6 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.9 0.2 0.0 0.0 2.3 264.7 0.4 0.0 0.0 35.9 0.4 8.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 184.2 0.1 0.0 0.2 0.1 0.3 0.2 0.0 1.3 0.2 114.6 0.0 33.1 3823.3 177.9 10.2 6550.1 12.7 57.5 10.8 9.3 2043.3 6.3 33.1 26.2 2943.0 14.5 7744.5 144.2 10.7 4449.8 24.9 25.5 26.6 33.0 25.0 31.3 45.1 36.4 36.8 34.3 32.1 42.7 12.0 25.6 59.6 0.0 39.2 32.5 0.7 0.0 0.6 0.1 5.3 24.3 7.5 18.6 19.2 42.3 0.0 11.1 31.2 1.0 0.0 0.3 1.9 0.6 0.7 28.7 1.2 65.0 0.0 0.4 15.4 20.6 0.5 0.4 68.3 0.4 35.3 13.4 1777.1 0.0 0.0 0.1 0.0 2140.2 1359.1 4.9 7.5 1494.0 39.2 10.3 1022.6 0.0 32.0 0.5 0.1 0.2 11.1 0.7 7.2 0.4 0.3 4.2 10.2 0.1 52.6 4.7 6.5 0.5 1.5 2.1 28.3 22.7 46.1 1.9 0.6 0.3 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 AIFM2 "AMID, FLJ14497, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 173.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cytosol" "HPA028961: AB_2672844, HPA042309: AB_10796575, HPA075576: " "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (4.29e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.26e-3)" "unprognostic (2.57e-2)" "unprognostic (7.95e-3)" "unprognostic (2.80e-1)" "unprognostic (5.31e-2)" "unprognostic (8.90e-2)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.49e-1)" "unprognostic (4.59e-3)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.92e-4)" 39.6 13.5 7.5 6.3 8.1 1.9 31.2 7.3 8.0 6.9 8.6 12.9 9.3 7.8 9.0 13.3 6.8 5.0 17.0 6.9 7.7 10.4 21.9 9.3 5.1 8.2 7.3 7.9 5.0 3.2 5.6 4.1 6.9 9.9 7.1 2.4 7.6 7.7 9.8 5.6 11.5 5.0 6.2 7.7 9.9 3.9 8.3 2.4 14.6 7.3 3.6 12.0 6.3 6.5 26.5 45.2 1.1 11.3 26.2 9.8 0.3 10.4 25.5 21.0 23.6 35.3 49.8 3.8 25.8 14.5 27.5 27.9 12.7 3.8 5.9 50.8 1.9 0.2 27.3 173.3 56.1 0.3 6.4 13.3 8.4 33.8 7.2 13.2 9.5 1.7 20.5 21.9 11.0 33.5 1.2 1.3 4.5 21.2 14.6 0.8 4.2 12.4 11.4 19.2 3.6 0.8 19.1 16.6 29.8 1.8 0.7 7.2 12.0 0.5 25.3 15.6 30.8 16.2 32.7 7.3 14.0 0.9 13.9 1.0 0.5 0.5 1.8 0.5 1.5 1.7 0.6 1.5 0.4 1.5 0.8 1.3 0.5 4.0 0.5 0.2 1.3 0.7 7.5 8.1 7.3 8.0 6.9 7.7 8.2 7.3 6.9 6.2 8.3 6.5 11.6 6.4 14.1 7.2 5.0 2.3 15.0 8.4 2.8 5.7 5.5 4.7 13.8 8.6 10.5 18.4 0.0 13.9 1.4 53.1 3.9 40.7 24.1 6.0 7.7 4.8 12.0 7.0 8.2 21.9 3.0 11.2 14.3 6.2 11.4 22.3 1.8 25.0 10.2 1.7 5.2 7.1 14.2 3.3 3.3 47.0 5.3 6.7 8.8 4.7 34.4 4.8 1.0 5.5 3.5 40.8 22.7 4.5 17.0 14.6 28.7 22.6 9.5 2.1 19.7 11.8 12.8 6.2 3.9 5.1 1.4 18.6 3.8 8.8 13.7 20.4 AKNAD1 "C1orf62, MGC26989" ENSG00000162641 "AKNA domain containing 1" Q5T1N1 1 108815898-108963484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.8" "Cell type enriched" "Detected in some" 4 "Early spermatids: 80.6" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.1;hTCEpi: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030270, HPA030271, HPA030272" Uncertain Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Microtubules, Cytokinetic bridge" "HPA030270: AB_10610980, HPA030271: AB_10600873, HPA030272: AB_10601342" "unprognostic (4.93e-2)" "unprognostic (1.72e-1)" "unprognostic (5.52e-2)" "unprognostic (2.00e-3)" "unprognostic (7.22e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-5)" "unprognostic (8.15e-2)" "unprognostic (5.95e-2)" "unprognostic (2.83e-2)" "unprognostic (1.89e-1)" "unprognostic (2.24e-1)" "unprognostic (3.00e-8)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "unprognostic (5.75e-2)" "unprognostic (8.22e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.7 0.0 0.0 1.6 0.0 1.5 0.1 0.0 1.8 2.5 0.5 0.9 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.2 80.6 0.3 5.1 1.4 0.0 0.0 1.0 0.2 0.8 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.7 0.0 0.0 0.3 17.8 2.5 0.1 1.8 0.0 0.0 0.4 0.0 3.5 3.1 0.2 0.0 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.9 0.6 1.4 0.1 0.1 0.7 0.1 0.7 0.5 0.0 AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 623.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 253.8;Basal squamous epithelial cells: 262.4;Cholangiocytes: 284.5;Exocrine glandular cells: 328.0;Hepatocytes: 597.7;Squamous epithelial cells: 229.3;Urothelial cells: 306.0" "Cancer enhanced" "Detected in many" "liver cancer: 64.2;lung cancer: 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 8 "ASC diff: 2988.3;Hep G2: 5415.7;OE19: 2297.1" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: AB_2685966" "unprognostic (1.54e-2)" "prognostic favorable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favorable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" 185.7 14.3 12.3 13.5 16.5 5.8 116.2 16.0 11.5 12.9 6.9 23.2 25.3 6.6 6.6 103.9 11.5 65.7 135.5 10.9 18.7 45.4 623.2 28.9 4.7 22.1 18.4 15.5 23.3 0.8 9.7 1.7 23.2 17.3 12.2 11.5 73.7 12.5 120.4 35.3 23.4 8.7 19.6 4.1 142.9 13.0 22.2 4.6 46.7 27.3 7.8 71.1 31.3 20.3 0.0 429.6 2.4 426.7 2988.3 358.2 0.2 13.7 95.9 5.4 4.1 8.4 0.5 0.0 6.1 97.7 72.5 3.6 1.6 22.4 2.5 0.1 0.2 12.6 65.6 5415.7 30.0 1.8 0.0 183.9 27.3 44.2 26.7 0.4 10.2 2.9 95.8 0.4 74.7 2.4 0.1 0.4 1.2 2297.1 1.5 0.1 0.8 4.2 24.3 81.4 0.4 1.7 23.8 0.7 0.8 1.3 0.5 7.8 85.3 36.0 2.3 97.6 4.5 1.6 0.5 0.3 129.3 12.1 0.9 1.5 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.2 0.1 0.2 12.3 16.5 16.0 11.5 10.9 18.7 22.1 18.4 23.2 19.6 22.2 20.3 21.6 67.3 34.4 2.0 2.4 21.2 27.8 253.8 262.4 3.1 7.6 1.0 3.2 284.5 144.5 62.5 0.0 0.1 0.2 5.9 13.7 67.0 24.0 3.3 1.7 17.1 1.8 52.6 3.4 328.0 0.1 176.3 139.1 4.6 4.5 0.8 21.0 597.7 0.4 0.0 3.1 6.8 20.3 16.1 15.6 9.9 151.6 3.3 106.7 13.1 4.6 51.5 0.0 4.5 0.5 120.2 3.6 147.4 0.4 41.3 20.2 61.9 72.2 4.5 0.0 16.4 24.3 1.9 1.1 229.3 20.5 0.1 2.1 6.4 20.3 306.0 AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 341.5;liver: 481.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 141.7;Club cells: 128.8;Gastric mucus-secreting cells: 133.5;Hepatocytes: 397.4;Urothelial cells: 271.9" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "A549: 2054.8;ASC diff: 2439.5;Hep G2: 3926.2;OE19: 2684.9;RT4: 1178.9" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: AB_2685966" "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" 341.5 20.8 9.8 10.0 11.6 1.0 205.6 10.7 12.9 17.4 8.1 37.1 29.6 5.6 3.3 202.5 8.6 98.1 83.8 7.2 16.6 43.0 481.9 23.5 2.1 18.7 13.7 10.4 11.8 1.1 8.1 0.8 17.1 11.7 13.3 15.2 116.5 12.9 286.9 42.5 33.7 9.2 11.5 2.1 137.0 11.8 16.8 4.4 38.3 36.5 9.3 253.9 47.0 9.7 0.0 2054.8 2.4 214.1 2439.5 83.4 0.1 0.7 8.6 0.9 2.0 8.1 0.2 0.4 11.5 14.2 10.0 57.8 0.2 10.7 1.2 0.6 0.2 0.7 516.4 3926.2 4.6 0.4 0.9 218.3 126.4 10.5 10.4 0.7 0.9 0.3 81.9 0.3 20.4 3.3 0.2 0.0 0.7 2684.9 0.8 0.3 0.6 34.6 19.0 1178.9 1.2 0.4 21.2 0.3 0.1 0.4 0.5 4.0 8.6 5.1 1.8 74.6 0.8 0.6 0.6 0.3 25.9 30.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 11.6 10.7 12.9 7.2 16.6 18.7 13.7 17.1 11.5 16.8 9.7 15.2 12.8 2.8 0.0 0.9 11.9 9.5 141.7 20.5 1.9 0.8 1.4 5.5 102.9 128.8 0.0 0.0 0.0 0.0 10.3 0.0 18.3 17.3 0.7 0.5 7.5 1.8 8.0 2.6 103.3 0.1 44.2 133.5 0.8 0.0 0.1 10.8 397.4 0.1 3.3 4.2 5.4 46.8 12.0 7.8 7.8 79.2 1.0 8.8 19.7 0.6 39.6 0.0 5.5 0.3 90.0 6.6 78.6 0.8 23.7 15.9 3.6 40.3 3.0 0.0 5.3 13.9 0.2 0.3 112.9 13.5 0.0 1.3 0.4 8.5 271.9 AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cell line enhanced" "Detected in many" "A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" 164.4 50.2 31.1 25.4 34.6 42.3 115.2 32.1 42.4 21.9 30.2 185.9 441.3 25.9 4.4 53.2 42.1 261.1 42.9 31.5 35.6 177.7 268.0 48.3 7.6 30.3 33.9 17.8 36.4 22.5 10.4 4.7 32.3 10.3 98.0 19.1 40.5 19.4 116.9 27.0 270.9 39.2 30.3 3.8 237.4 10.0 31.5 37.4 26.4 34.8 6.6 84.7 22.2 31.1 0.1 1615.1 1.1 413.0 811.9 292.2 1.0 0.0 21.4 0.4 1.4 47.6 24.5 0.2 78.7 19.4 45.0 11.5 1.5 28.8 1.1 3.0 0.5 3.2 438.4 699.6 4.3 0.7 0.2 160.9 57.1 20.0 0.7 25.8 28.1 3.4 10.8 0.0 42.6 3.8 9.8 2.6 0.7 3025.3 4.3 3.3 9.6 43.7 149.0 639.2 1.0 2.9 232.2 0.0 0.3 0.9 0.5 0.2 221.7 5.2 4.7 87.8 3.1 0.7 0.7 0.3 45.8 62.8 4.4 244.0 2.9 4.8 102.6 0.9 6.9 0.0 19.0 18.7 2.1 0.5 11.6 8.9 7.3 21.1 1.4 39.6 21.4 42.4 31.1 34.6 32.1 42.4 31.5 35.6 30.3 33.9 32.3 30.3 31.5 31.1 144.2 44.8 5.3 4.9 4.3 12.0 3.7 393.1 2.8 2.0 15.8 5.5 3.9 0.0 172.9 36.8 0.0 0.4 64.4 133.8 43.0 114.6 3.3 67.5 4.5 67.5 19.2 34.9 2.5 722.5 0.0 44.3 158.0 66.4 5.7 0.1 0.0 0.0 1.6 1.7 3.2 65.9 61.1 0.0 14.0 4.9 78.3 14.8 21.4 7.5 4.1 132.7 202.9 14.6 0.0 266.1 219.6 106.8 3.1 1.3 576.9 601.8 112.8 5.3 26.3 15.5 20.3 0.5 4.3 20.2 10.7 0.0 14.4 7.8 196.9 46.4 AL845331.1 ENSG00000259916 "Putative aquaporin-7-like protein 3" 2 94588522-94604573 "Metabolic proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "adipose tissue: 7.5;breast: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "ASC diff: 1.9" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (8.07e-3)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (9.15e-3)" "unprognostic (6.22e-2)" "unprognostic (4.66e-2)" 7.5 0.1 0.0 0.0 0.5 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1500.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 389.4;Hepatocytes: 624.4;Leydig cells: 406.4;Proximal tubular cells: 375.4;Respiratory ciliated cells: 583.7" "Cancer enhanced" "Detected in all" "liver cancer: 399.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.3" "Lineage enriched" "Detected in many" 33 "monocytes: 87.3" "Cell line enhanced" "Detected in many" "A549: 4019.8;Hep G2: 1269.3;RPTEC TERT1: 710.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 378.3" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "CAB020690: , HPA002123: AB_1844722" "unprognostic (8.46e-3)" "prognostic favorable (7.77e-5)" "unprognostic (5.59e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-2)" "unprognostic (8.71e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (4.53e-2)" "unprognostic (6.83e-2)" "unprognostic (4.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.24e-3)" "unprognostic (2.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-3)" 109.4 182.4 51.3 28.4 71.9 31.8 64.3 125.1 72.4 121.8 35.7 218.2 549.7 139.3 583.4 41.3 184.3 175.4 53.7 64.6 62.1 335.4 1500.8 142.6 31.2 93.4 370.7 222.7 498.1 24.3 164.4 32.0 84.7 57.2 88.8 0.4 104.5 245.4 66.7 17.2 304.3 117.0 104.2 77.5 568.5 149.5 74.5 19.8 211.7 83.0 21.6 31.6 90.7 106.1 0.0 4019.8 0.4 0.0 22.4 0.2 1.4 139.6 0.0 0.1 0.1 136.2 0.0 0.1 50.5 0.0 0.3 2.6 0.0 0.2 0.1 0.4 0.1 232.1 0.6 1269.3 13.7 0.6 0.3 6.7 0.1 0.0 0.0 0.3 143.0 0.0 16.9 0.0 153.3 7.2 0.2 1.8 0.7 7.2 0.4 0.5 44.0 1.8 710.6 1.1 0.3 1.4 0.3 0.4 2.9 0.2 0.0 0.5 0.7 0.0 3.5 0.5 0.3 0.4 0.2 1.0 0.0 1.7 0.4 0.0 87.3 1.4 0.0 14.9 0.0 0.0 0.2 0.1 1.4 0.7 0.0 0.0 2.6 0.0 1.1 1.0 0.0 30.3 51.3 71.9 125.1 72.4 64.6 62.1 93.4 370.7 84.7 104.2 74.5 106.1 4.9 96.1 107.6 31.3 6.9 2.7 18.3 168.3 1.2 0.4 12.6 1.7 4.3 187.3 361.1 115.8 0.0 1.7 0.1 20.2 389.4 71.6 12.6 6.3 125.2 26.4 54.9 96.1 3.5 349.7 1.0 102.7 258.4 8.1 158.9 0.2 133.5 624.4 134.4 0.0 0.5 168.9 138.4 109.6 5.1 37.8 406.4 61.7 7.2 17.8 46.0 0.0 2.1 0.0 0.7 128.4 77.4 207.3 1.3 2.0 267.4 375.4 583.7 0.3 26.3 334.2 28.6 8.6 4.6 21.5 3.1 2.5 8.8 129.6 131.7 26.5 ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 369.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 633.3;Proximal tubular cells: 197.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.5;Hep G2: 78.1;Karpas-707: 82.0;RPMI-8226: 45.0;RT4: 219.1;U-266/70: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 3000000 "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favorable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" 76.4 37.2 53.4 2.0 63.2 0.4 28.8 55.9 63.6 15.6 37.7 10.1 0.2 7.2 2.5 6.6 16.0 2.3 26.5 47.5 56.2 116.6 369.7 3.1 0.3 56.7 52.9 45.3 44.3 15.1 4.5 0.0 53.0 14.6 5.4 8.7 88.6 6.9 90.7 3.5 5.6 2.0 48.4 0.4 9.5 15.0 53.9 3.7 2.6 59.9 4.6 28.3 6.4 46.0 1.3 0.0 0.0 0.0 36.5 0.0 0.4 0.3 1.5 0.4 0.6 0.0 3.2 2.6 10.2 0.0 2.1 0.4 0.6 1.5 0.7 0.0 0.2 0.1 0.3 78.1 10.6 10.6 0.2 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 82.0 1.6 0.0 0.0 0.2 0.3 1.1 0.0 0.1 0.2 45.0 0.7 219.1 0.4 0.3 1.3 10.6 0.0 0.6 0.1 0.0 0.3 1.4 6.2 0.0 0.1 44.8 14.8 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 63.2 55.9 63.6 47.5 56.2 56.7 52.9 53.0 48.4 53.9 46.0 0.8 0.0 6.0 92.7 4.6 0.1 53.5 9.1 1.8 0.2 14.4 2.2 16.1 38.6 44.0 12.9 0.0 0.0 0.1 7.2 72.4 2.9 22.3 57.2 5.2 4.6 1.2 34.7 0.6 5.6 0.2 9.1 0.0 3.6 27.8 12.4 17.2 633.3 0.1 0.0 3.0 17.6 2.0 24.5 1.9 35.0 26.4 9.3 3.6 3.7 0.0 40.0 0.0 11.1 0.2 2.2 0.4 22.6 0.0 12.2 0.8 197.4 32.2 1.4 6.6 10.5 5.3 1.6 4.3 1.7 0.0 0.1 2.8 0.9 5.6 61.7 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Cell line enhanced" "Detected in many" "ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 303.8 102.4 139.7 39.8 146.1 29.2 77.2 136.5 163.5 25.0 123.3 73.3 73.7 30.1 21.3 73.6 32.3 37.4 111.3 132.2 139.7 177.7 857.7 111.6 18.7 140.7 144.9 42.0 23.3 2.6 23.3 7.0 141.1 34.6 72.3 29.2 32.4 29.5 130.8 127.9 74.8 30.2 143.0 20.6 101.5 13.0 151.8 27.1 30.8 165.7 52.9 50.0 29.0 144.5 8.8 13.1 18.7 31.9 86.8 13.0 60.9 9.3 16.8 4.3 3.1 23.5 12.1 0.5 45.3 20.8 11.9 16.2 0.1 4.6 2.7 0.6 6.1 0.7 8.4 64.7 97.0 0.9 0.9 23.9 22.6 14.8 0.3 17.7 26.9 0.9 17.9 3.0 4.1 0.5 1.0 23.4 24.8 152.2 2.1 0.6 0.4 1.9 31.4 0.6 7.5 23.1 22.8 201.0 0.2 33.7 20.3 92.1 1.1 0.4 16.5 0.6 0.4 5.5 3.0 25.7 22.0 0.8 0.4 6.5 212.0 51.1 0.7 93.0 0.9 6.2 0.3 0.7 213.2 5.2 0.7 0.5 10.7 3.4 25.4 70.6 0.5 123.5 139.7 146.1 136.5 163.5 132.2 139.7 140.7 144.9 141.1 143.0 151.8 144.5 27.7 147.4 242.7 51.2 22.6 60.0 205.2 311.1 80.8 78.7 35.0 23.7 378.9 165.8 243.1 66.2 18.8 62.4 48.6 260.3 399.2 127.5 4.3 27.8 24.5 66.2 55.2 42.1 11.7 218.0 127.5 103.1 200.3 47.7 30.9 29.0 139.6 857.0 129.2 35.3 18.2 231.0 101.7 278.5 124.1 10.6 79.9 189.3 35.6 26.2 940.8 130.2 8.2 14.1 6.8 130.2 366.5 149.0 12.5 84.4 384.3 882.0 89.4 42.6 46.0 46.0 67.6 3.0 3.9 105.1 124.7 42.1 13.1 81.0 272.6 150.4 ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662160-67681224 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 73.0;esophagus: 152.2;skin 1: 123.0;vagina: 41.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 26.2;Endometrial ciliated cells: 12.6;Glandular and luminal cells: 28.1;Squamous epithelial cells: 53.3;Suprabasal keratinocytes: 14.8;Syncytiotrophoblasts: 14.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 71.9;SK-BR-3: 70.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045132 Approved NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA045132: AB_10795993" "unprognostic (2.25e-1)" "unprognostic (2.41e-1)" "unprognostic (1.65e-1)" "unprognostic (8.65e-2)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (5.92e-2)" 0.3 0.0 0.1 0.1 0.0 0.2 73.0 0.0 0.0 14.4 0.0 0.1 0.1 0.8 6.8 152.2 4.6 0.3 0.1 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.3 5.2 0.1 3.2 0.0 3.3 0.1 0.5 17.3 4.8 0.3 123.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 2.4 0.0 0.0 21.1 8.3 41.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 7.9 0.0 0.0 0.1 0.0 1.3 3.5 3.3 0.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.9 6.8 0.0 0.1 9.0 0.0 0.0 0.0 1.9 0.0 13.0 0.0 0.1 0.0 70.7 0.1 0.4 15.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 1.7 1.2 4.9 1.2 0.0 26.2 7.2 0.4 0.0 7.3 5.5 0.0 10.6 0.2 0.0 1.9 1.1 0.0 12.6 2.6 0.2 0.0 0.0 0.1 0.2 10.6 0.2 0.0 28.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.0 0.0 0.8 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 53.3 14.8 14.6 0.2 0.0 0.0 7.6 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 200.4;liver: 436.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 83.7;SK-BR-3: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 58000 "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: " "unprognostic (1.17e-1)" "prognostic favorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 70.8 16.1 73.9 3.9 88.9 11.7 21.6 73.8 95.9 12.6 106.5 6.8 1.6 9.8 4.7 36.3 8.3 5.5 33.0 68.2 73.8 200.4 436.6 6.2 3.4 72.9 82.8 7.3 4.6 23.0 9.7 13.2 70.0 29.5 2.7 6.5 9.1 27.1 74.2 19.2 4.7 7.1 65.6 7.5 12.5 3.2 92.4 11.7 7.1 74.8 4.2 19.3 16.8 66.1 12.7 17.8 9.5 29.2 40.0 5.7 25.2 13.1 7.1 11.8 9.5 13.7 8.9 8.8 16.6 15.6 5.7 34.0 16.7 35.4 4.5 4.8 15.9 5.9 5.0 83.7 12.6 4.4 15.1 15.6 19.2 6.5 6.6 9.0 13.5 14.0 21.0 5.7 8.1 32.3 4.3 20.2 4.7 26.0 10.1 27.9 8.4 10.0 12.1 32.0 19.6 7.6 21.9 85.0 16.1 14.7 38.7 6.3 11.3 10.2 14.0 12.2 4.5 7.1 17.9 2.5 3.4 33.7 13.5 0.0 2.7 1.5 0.6 3.6 0.5 0.8 0.3 0.8 4.4 0.7 0.2 0.5 0.3 0.1 2.0 1.5 0.6 1.5 73.9 88.9 73.8 95.9 68.2 73.8 72.9 82.8 70.0 65.6 92.4 66.1 2.6 0.0 2.8 27.1 4.3 7.5 17.9 12.5 17.6 3.7 9.8 8.5 20.9 34.3 2.9 46.0 10.4 78.0 2.0 2.0 46.9 6.5 0.5 1.1 1.7 3.1 2.4 32.2 1.2 0.9 12.6 3.2 7.7 3.9 4.5 2.1 15.4 385.1 13.8 20.2 1.6 3.6 6.1 17.2 1.4 0.6 1.2 4.7 3.6 1.9 10.9 14.0 1.0 5.5 1.3 2.5 1.8 2.6 4.4 12.0 0.3 279.4 1.7 4.8 6.6 2.6 4.7 2.2 3.9 21.7 5.4 86.6 2.6 4.5 4.0 9.5 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Cell line enhanced" "Detected in all" "T-47d: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 38.7 14.7 58.6 4.8 66.0 3.3 14.4 58.8 59.3 17.3 61.4 15.2 26.6 11.4 9.8 9.8 12.8 9.4 40.3 51.0 54.0 379.1 367.1 9.4 5.1 63.3 54.0 28.3 23.4 37.0 6.6 7.6 55.6 25.4 15.8 15.2 19.8 16.1 27.5 6.2 23.4 9.0 56.4 5.4 24.0 17.1 69.8 5.7 28.3 34.8 5.3 11.4 7.0 62.6 8.9 7.8 11.0 23.5 39.3 19.2 17.5 6.3 11.8 6.8 11.5 17.3 10.2 10.5 13.6 13.5 5.3 4.8 24.9 7.0 14.5 9.5 3.5 5.1 8.0 19.2 45.0 2.7 2.4 28.2 12.0 8.7 20.7 17.0 12.0 23.7 8.1 14.7 4.6 36.2 7.6 4.0 8.7 32.6 5.2 15.1 11.2 14.6 9.2 5.8 4.4 7.0 21.0 21.9 5.7 18.0 57.5 9.6 3.8 7.4 9.0 11.7 2.4 9.3 18.9 10.2 9.9 3.2 7.3 29.1 6.2 43.2 6.9 4.8 10.6 7.2 7.8 8.4 9.2 6.1 9.9 7.0 2.4 9.7 4.2 5.3 6.1 4.9 58.6 66.0 58.8 59.3 51.0 54.0 63.3 54.0 55.6 56.4 69.8 62.6 15.4 38.5 60.4 24.5 11.8 9.2 26.8 10.0 20.5 20.6 28.4 18.9 81.4 67.2 22.9 66.2 4.2 31.0 7.1 18.9 201.5 11.6 23.4 26.2 27.5 27.0 16.9 28.6 5.5 3.1 14.8 25.9 34.7 90.2 7.6 27.1 87.4 523.6 17.7 11.8 10.0 39.3 8.2 26.5 8.9 19.0 28.9 13.4 24.9 1.9 15.8 98.5 9.2 12.5 23.4 4.1 16.3 48.2 8.0 27.6 55.3 962.4 15.4 17.0 13.1 25.6 16.9 11.0 4.2 25.2 7.4 30.6 11.0 10.2 35.7 17.2 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.5;Horizontal cells: 274.2;Muller glia cells: 127.1;Proximal enterocytes: 120.0;Rod photoreceptor cells: 348.5" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 250.9;U-266/70: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 87.0 24.3 953.6 12.7 909.7 23.6 42.5 1238.3 1162.3 39.3 589.6 18.5 18.7 17.9 10.9 40.8 14.3 10.9 285.5 955.7 958.0 16.8 98.3 13.7 19.3 1297.5 962.6 39.1 4.9 12.1 30.6 4.1 1384.6 18.9 14.7 1183.1 19.9 15.8 4.8 74.5 43.9 12.4 926.9 24.4 23.3 14.2 1090.2 9.6 7.4 8.1 30.5 19.0 47.0 886.1 29.9 2.1 13.7 55.7 29.9 32.9 2.9 16.7 37.7 12.9 76.0 17.9 3.0 14.9 17.3 15.5 3.3 36.9 10.3 102.3 23.4 12.4 8.9 28.3 11.6 30.4 25.8 10.0 29.2 27.8 13.9 1.5 24.0 1.7 5.3 29.7 19.3 71.9 10.7 15.1 11.9 32.0 20.8 6.7 15.3 9.5 1.6 250.9 1.9 4.3 36.2 61.9 9.1 67.3 0.5 20.8 36.6 21.2 3.5 1.2 5.3 2.1 2.4 161.0 51.4 10.9 105.2 28.0 1.9 0.5 7.4 3.0 21.6 8.7 30.6 24.0 29.5 17.8 9.4 25.1 37.7 28.4 18.0 29.4 5.3 4.6 40.9 19.0 953.6 909.7 1238.3 1162.3 955.7 958.0 1297.5 962.6 1384.6 926.9 1090.2 886.1 4.2 0.0 15.8 97.6 9.8 7.5 20.3 80.5 8.6 112.5 9.0 11.0 22.1 11.5 29.3 7.3 106.3 1.1 9.5 31.7 3.9 21.9 0.9 1.0 3.0 11.3 21.6 3.2 19.2 10.2 6.5 5.8 6.6 1.2 13.3 4.9 14.3 93.1 5.4 274.2 41.3 12.9 28.5 4.4 5.3 1.3 9.3 3.1 24.9 21.5 34.1 127.1 12.3 26.7 16.8 12.4 12.4 10.1 2.6 6.1 120.0 2.1 11.8 348.5 13.1 6.4 10.1 0.3 3.2 7.9 10.9 1.5 17.0 11.7 5.1 7.8 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 72.8;lymphoid tissue: 93.9" "Cell type enhanced" "Detected in many" "B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA071285: AB_2686379" "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favorable (7.18e-4)" 16.8 8.4 1.4 8.4 1.1 31.1 12.7 2.8 2.9 6.1 1.0 11.0 3.0 6.9 0.3 10.7 11.1 3.4 6.7 1.2 1.8 8.3 5.5 72.8 6.7 4.1 2.5 2.6 23.2 0.9 3.2 3.6 2.7 11.8 2.3 0.1 14.1 1.5 2.1 5.6 35.8 4.9 2.5 93.9 9.3 2.1 2.2 2.6 4.7 3.7 8.9 40.0 7.9 4.2 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 7.4 40.9 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 8.6 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 2.7 0.0 5.2 0.7 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.0 0.0 2.2 0.0 0.0 30.8 2.8 11.0 0.0 0.1 0.0 462.5 225.6 317.6 0.3 198.4 0.6 133.9 5.3 1.7 119.7 98.5 0.7 0.5 457.8 0.2 210.5 2.4 1.2 136.1 1.4 1.1 2.8 2.9 1.2 1.8 4.1 2.5 2.7 2.5 2.2 4.2 0.7 16.0 38.4 1.3 63.7 1.1 7.3 0.2 1.2 1.3 7.3 4.3 2.2 12.8 9.5 9.2 2.1 0.7 1.7 1.7 0.0 20.9 0.5 0.7 0.5 3.0 7.1 1.7 2.8 21.6 2.0 1.7 13.7 4.4 201.3 2.2 3.6 1.1 85.0 0.0 1.1 2.0 14.2 78.5 17.8 1.1 0.3 86.5 0.0 47.8 59.5 0.7 4.1 4.0 1.4 18.4 0.6 0.0 13.8 4.0 9.4 0.2 2.6 0.3 13.1 0.3 1.1 0.3 1.1 9.2 1.4 4.1 5.9 0.7 3.2 45.3 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 ALPK3 "KIAA1330, MAK, Midori" ENSG00000136383 "Alpha kinase 3" Q96L96 15 84817356-84873479 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 62.7;skeletal muscle: 195.8;tongue: 59.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 64.1;Exocrine glandular cells: 20.5;Skeletal myocytes: 51.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.3;HDLM-2: 10.7;HUVEC TERT2: 15.5;LHCN-M2: 21.2;NTERA-2: 12.9;RH-30: 37.7;THP-1: 9.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA026558 Uncertain Approved Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "HPA026558: AB_1844774" "unprognostic (2.69e-2)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (4.61e-2)" "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.44e-3)" "unprognostic (1.42e-1)" "unprognostic (1.68e-2)" "unprognostic (1.82e-1)" "unprognostic (1.74e-3)" "unprognostic (1.23e-1)" "prognostic favorable (3.95e-7)" "unprognostic (1.76e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (4.87e-2)" 12.5 9.6 1.2 0.9 1.6 0.1 4.4 1.0 2.2 2.2 9.3 7.5 0.6 1.5 5.4 3.0 1.7 1.8 62.7 1.3 3.8 13.5 5.9 5.5 0.6 2.2 3.4 0.8 7.7 11.2 26.1 2.5 4.5 2.4 0.8 2.5 2.6 1.3 195.8 1.0 2.1 3.1 1.6 0.5 5.2 0.9 3.9 0.6 3.6 59.1 0.4 3.6 1.4 1.1 1.8 0.1 0.1 0.2 0.3 0.1 14.3 0.0 0.0 0.0 0.1 0.1 6.3 0.0 0.4 0.0 0.1 1.1 0.0 0.0 0.1 10.7 1.7 1.8 0.3 0.0 0.2 0.0 0.1 1.3 0.2 0.0 0.0 0.1 15.5 0.1 0.0 0.1 21.2 0.9 0.0 0.2 12.9 0.3 0.1 0.0 37.7 0.2 0.0 4.0 0.0 0.2 0.0 2.0 0.1 1.9 0.1 9.6 0.3 0.1 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 1.0 2.2 1.3 3.8 2.2 3.4 4.5 1.6 3.9 1.1 3.3 6.4 2.7 2.6 0.2 0.9 0.1 0.6 1.2 4.1 1.3 0.8 64.1 17.2 2.4 9.2 16.7 0.3 0.2 0.5 0.0 2.9 0.3 11.5 1.0 8.7 9.1 0.0 3.0 20.5 0.7 3.8 0.5 8.9 1.3 8.7 1.8 1.7 10.2 0.0 3.4 0.3 0.0 0.3 12.0 0.0 0.0 5.2 3.6 9.4 4.7 1.0 1.0 0.5 0.3 10.4 1.2 0.0 1.5 0.7 0.1 2.2 4.2 3.4 0.0 51.9 8.4 0.5 3.2 0.2 0.1 0.7 0.5 0.2 0.3 1.6 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 AMIGO2 "ALI1, DEGA" ENSG00000139211 "Adhesion molecule with Ig like domain 2" Q86SJ2 12 47075707-47079959 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Enteroendocrine cells: 60.4;Glandular and luminal cells: 72.8;Granulosa cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 192.0;fHDF/TERT166: 183.2;hTERT-RPE1: 312.2;LHCN-M2: 179.2;RT4: 251.9;U-2 OS: 149.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054004, HPA059601" Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" NA Yes 390000 "Cluster 32: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Plasma membrane" Cytosol "HPA054004: AB_2682339, HPA059601: AB_2684078" "unprognostic (2.63e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" "unprognostic (3.91e-2)" "unprognostic (3.86e-1)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (2.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-2)" "unprognostic (2.95e-1)" "unprognostic (7.47e-2)" "unprognostic (2.29e-3)" 10.8 19.8 4.5 7.0 4.9 3.5 22.8 3.6 5.4 20.3 2.3 39.4 3.3 30.7 7.9 4.0 36.4 19.3 5.6 3.2 8.8 7.7 4.6 20.0 12.4 9.1 37.9 28.7 3.6 6.4 5.3 13.2 19.6 11.3 9.0 25.7 4.5 11.0 1.1 4.4 12.6 34.3 4.3 17.4 5.5 10.7 13.1 2.8 4.2 2.2 7.6 22.6 14.3 3.9 44.4 105.5 6.3 0.2 2.5 0.2 17.2 14.8 39.3 4.7 3.8 0.3 192.0 0.0 47.6 183.2 117.0 64.8 0.0 117.6 5.5 8.6 0.7 0.0 11.0 0.1 3.8 1.2 1.7 0.9 20.1 122.6 59.5 312.2 15.0 0.9 8.5 0.0 179.2 2.1 3.6 0.1 4.5 21.2 27.1 0.3 46.5 0.1 52.3 251.9 18.8 0.0 76.2 9.0 0.5 3.4 11.2 1.0 4.1 2.6 149.9 1.7 121.3 1.9 0.4 0.2 10.0 3.4 2.8 0.0 0.1 0.0 4.4 0.2 6.0 3.7 6.8 6.9 0.7 1.6 15.3 12.1 0.1 8.6 0.0 8.8 4.4 4.7 4.5 4.9 3.6 5.4 3.2 8.8 9.1 37.9 19.6 4.3 13.1 3.9 7.2 9.6 3.1 1.0 3.6 2.4 13.1 39.4 15.4 62.6 10.8 37.7 1.6 1.5 4.9 1.8 0.0 1.0 12.4 0.4 1.9 5.3 1.4 31.5 6.0 12.7 60.4 5.7 2.6 19.3 28.1 11.1 0.5 72.8 7.0 76.8 32.2 1.2 4.8 0.0 0.2 3.1 2.0 3.5 1.1 2.3 2.5 7.2 1.8 1.9 5.3 15.6 2.1 0.0 0.1 40.4 1.5 0.7 3.8 10.7 0.0 0.1 2.9 4.9 0.0 3.2 27.7 0.7 2.4 2.5 0.4 8.5 7.6 12.8 0.3 33.9 AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 559.2;tongue: 211.4" "Group enriched" "Detected in some" 6 "Plasma cells: 43.8;Skeletal myocytes: 13.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 29 "U-266/70: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" NA NA 38000 "Cluster 37: B-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" 0.1 0.1 0.0 0.5 0.0 0.3 3.0 0.0 0.0 0.2 0.0 5.6 16.4 0.2 0.0 5.8 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.0 3.5 5.5 0.0 4.4 0.9 559.2 0.0 7.5 0.1 0.0 1.6 3.7 0.1 0.0 0.4 0.1 211.4 2.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.8 1.9 0.0 0.0 0.0 3.0 4.2 0.0 0.0 0.0 43.8 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANGPTL8 "C19orf80, RIFL, TD26" ENSG00000130173 "Angiopoietin like 8" Q6UXH0 19 11237450-11241943 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Hormone "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 409.8" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 151.2" "Cancer enriched" "Detected in some" 37 "liver cancer: 84.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "Hep G2: 37.0;MCF7: 21.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA042131 Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 836000 350000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" Nucleoplasm "HPA042131: AB_10794413" "unprognostic (2.37e-2)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-2)" "unprognostic (1.17e-1)" "unprognostic (1.00e-1)" "unprognostic (3.73e-1)" "unprognostic (2.80e-1)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" "unprognostic (9.67e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (4.57e-1)" "unprognostic (1.75e-2)" 35.7 0.8 1.1 0.2 1.0 0.1 22.5 0.1 1.7 1.2 0.0 1.4 0.4 0.9 1.6 0.3 0.8 0.4 1.8 0.9 0.6 4.0 409.8 0.4 0.1 0.7 0.6 1.1 0.9 0.0 0.3 0.1 0.5 0.8 0.0 0.1 1.3 0.1 0.8 0.9 1.2 0.1 0.3 0.4 0.7 0.5 1.1 0.0 1.0 0.0 0.0 1.1 1.0 0.9 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 1.3 37.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 21.2 0.0 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.0 0.3 0.0 0.3 0.4 0.9 0.0 0.4 0.6 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.1 1.7 0.9 0.6 0.7 0.6 0.5 0.3 1.1 0.9 0.6 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.4 0.2 0.8 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.3 0.2 0.0 2.7 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 4.6 151.2 0.1 0.0 0.0 0.0 0.0 4.4 0.0 1.9 0.9 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.2 0.0 0.1 ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896762 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 993.4;tongue: 629.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 164.7;Cone photoreceptor cells: 87.6;Erythroid cells: 250.2;Inhibitory neurons: 176.8;Skeletal myocytes: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 9.2;naive B-cell: 7.8;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 4 "B-cells: 9.2;dendritic cells: 3.4" "Group enriched" "Detected in many" 4 "HEL: 125.2;K-562: 134.3;RH-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" NA NA 4200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" 1.8 1.1 0.4 1.6 2.0 95.2 1.0 34.1 17.3 0.3 0.0 0.5 1.5 0.1 0.1 8.7 0.4 0.8 98.0 0.3 12.5 0.6 0.3 0.7 4.4 26.8 32.6 0.3 0.8 62.1 1.1 2.1 27.1 4.2 0.2 6.3 8.1 0.7 993.4 0.6 0.9 0.3 10.6 2.2 4.4 0.6 8.4 0.7 0.6 629.0 4.0 1.8 0.5 5.4 0.0 16.8 0.5 0.0 0.2 2.9 0.0 4.9 32.8 1.5 0.7 0.1 0.0 7.7 1.5 3.5 0.6 2.8 0.8 0.5 0.7 3.2 0.1 125.2 0.7 0.0 0.1 0.3 0.4 4.2 0.6 0.4 0.0 0.7 0.1 0.0 134.3 2.8 2.1 0.3 0.0 1.6 1.7 0.1 0.1 0.9 160.2 0.8 0.7 0.5 2.2 1.4 0.1 2.3 0.0 5.9 2.0 3.2 0.8 0.5 0.9 27.6 0.2 0.0 0.2 4.7 2.9 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.4 9.2 0.3 0.4 0.1 7.8 0.0 0.0 0.4 0.1 0.0 3.4 1.0 0.7 0.4 2.0 34.1 17.3 0.3 12.5 26.8 32.6 27.1 10.6 8.4 5.4 5.5 0.0 0.0 1.3 8.3 0.6 1.4 2.2 0.6 15.4 0.3 0.1 164.7 0.0 1.0 0.0 87.6 1.1 0.2 0.1 1.9 0.1 7.0 0.1 0.1 4.6 1.2 250.2 12.9 0.0 0.5 2.9 5.6 0.5 0.0 2.2 0.4 0.1 19.7 3.3 176.8 0.7 2.0 0.8 3.7 6.3 0.3 2.6 0.0 3.7 0.4 1.0 0.0 7.1 2.0 1.1 1.2 0.4 5.7 1.3 0.1 0.3 0.6 5.5 0.0 51.6 5.7 0.2 1.0 0.1 0.0 0.4 1.7 0.1 0.0 1.8 ANKRD30A NY-BR-1 ENSG00000148513 "Ankyrin repeat domain 30A" Q9BXX3 10 37125725-37384111 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "breast: 38.1" "Group enriched" "Detected in some" 4 "Breast glandular cells: 295.9;Breast myoepithelial cells: 84.8" "Cancer enriched" "Detected in single" 37 "breast cancer: 11.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "A549: 2.7;U-266/70: 10.4" HPA071849 Uncertain Nucleoli NA NA "Cluster 5: Breast - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoli "HPA071849: " "unprognostic (2.79e-1)" "unprognostic (2.81e-1)" "unprognostic (1.01e-7)" "unprognostic (1.41e-1)" "unprognostic (5.93e-1)" 1.0 0.0 0.0 0.0 0.0 0.0 38.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 295.9 84.8 0.3 0.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 16.3 0.0 0.4 1.0 0.0 0.0 1.5 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 8.5 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 45.8 1.7 0.0 0.0 0.3 0.3 0.1 0.0 0.0 ANKRD53 "FLJ12056, FLJ36160" ENSG00000144031 "Ankyrin repeat domain 53" Q8N9V6 2 70978380-70985499 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.5" "Group enriched" "Detected in many" 21 "Early spermatids: 158.6;Late spermatids: 481.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HHSteC: 1.6;HSkMC: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049574 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA049574: AB_2680819" "unprognostic (6.11e-3)" "unprognostic (6.51e-2)" "unprognostic (1.70e-3)" "unprognostic (2.68e-1)" "unprognostic (2.01e-2)" "unprognostic (6.31e-3)" "unprognostic (2.20e-1)" "unprognostic (6.35e-2)" "unprognostic (3.53e-1)" "unprognostic (1.27e-1)" "unprognostic (6.39e-3)" "unprognostic (1.83e-1)" "unprognostic (1.13e-2)" "unprognostic (1.68e-3)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" 7.5 1.7 0.3 0.6 0.2 0.3 6.1 1.5 0.5 1.8 0.0 1.9 0.7 1.8 0.4 0.7 3.0 0.7 1.3 0.3 0.2 0.8 0.6 1.3 0.3 0.8 0.4 4.1 8.2 0.3 3.2 0.3 0.2 2.0 0.2 6.1 4.5 0.6 0.4 0.8 1.7 0.6 0.3 0.8 2.0 27.5 0.1 0.1 3.1 0.3 0.3 1.6 1.6 0.2 0.0 0.0 0.1 0.1 1.0 0.4 0.1 0.1 0.4 0.4 0.4 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.6 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.3 0.2 1.5 0.5 0.3 0.2 0.8 0.4 0.2 0.3 0.1 0.2 1.1 0.0 0.0 0.3 1.1 0.1 1.4 0.5 4.6 1.3 0.3 1.3 0.4 1.5 0.1 0.0 2.1 0.1 1.0 0.0 0.0 1.2 158.6 4.3 0.5 0.7 0.0 0.4 0.4 0.4 1.0 1.9 1.1 2.2 0.0 0.4 1.1 0.2 0.0 1.7 1.2 0.0 0.0 0.0 0.4 481.3 3.4 0.4 0.0 0.0 0.0 4.1 0.0 1.5 0.3 0.5 0.0 3.0 11.7 0.7 0.1 1.5 0.6 15.1 6.6 2.8 1.5 1.5 1.7 0.6 0.0 0.3 0.4 0.1 0.1 0.1 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 215.4;HHSteC: 197.9;LHCN-M2: 221.0;U-2197: 176.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 13000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.01e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-2)" "unprognostic (4.87e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-2)" "unprognostic (6.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.34e-6)" "unprognostic (1.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" 60.9 30.0 4.1 35.4 4.1 18.7 18.7 3.6 6.4 52.2 5.0 39.9 23.0 95.4 21.9 24.5 31.2 54.9 31.8 3.6 5.0 17.1 34.4 24.7 16.2 4.7 5.0 75.0 4.6 27.8 1.6 90.0 4.2 110.2 42.7 1.6 10.1 90.3 6.1 6.1 29.6 108.3 5.5 18.3 23.2 8.4 4.0 10.7 4.9 21.7 16.1 53.1 12.0 4.4 15.5 1.9 34.6 6.6 215.4 118.0 3.1 48.3 124.6 17.5 19.9 0.6 11.8 0.0 0.8 76.8 11.4 4.5 4.4 49.7 66.9 2.2 4.2 12.2 1.3 4.8 197.9 51.6 29.5 145.3 15.2 132.7 68.3 150.2 52.6 1.6 27.1 35.8 221.0 0.0 1.1 57.1 5.7 21.7 70.3 2.4 19.8 9.0 12.0 14.4 30.6 41.2 4.9 0.6 8.2 16.3 0.7 11.0 69.8 155.7 9.7 176.7 103.4 3.1 0.0 0.1 78.6 39.4 49.0 72.7 17.5 61.6 12.8 9.5 13.8 23.5 21.4 13.1 32.2 9.4 11.3 5.9 54.4 4.3 18.0 32.2 40.4 14.0 4.1 4.1 3.6 6.4 3.6 5.0 4.7 5.0 4.2 5.5 4.0 4.4 6.4 12.8 10.0 23.5 25.7 7.0 15.5 6.5 4.0 6.9 4.0 2.2 24.9 4.3 10.2 0.0 29.2 18.3 24.9 42.4 3.9 4.2 2.3 7.7 69.3 15.5 18.6 6.3 25.4 6.7 29.0 58.7 4.1 6.1 60.1 8.9 15.0 24.9 17.7 0.0 2.1 15.1 4.1 13.4 28.9 5.3 39.1 28.3 1.8 45.9 53.7 6.9 4.1 19.1 0.8 45.5 28.9 63.9 14.1 13.9 16.9 2.5 4.9 21.4 39.5 32.5 28.5 0.6 2.1 0.9 4.3 6.6 24.4 18.3 13.3 1.6 ANXA5 "ANX5, ENX2" ENSG00000164111 "Annexin A5" P08758 4 121667946-121696995 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Blood coagulation, Hemostasis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1156.8;Extravillous trophoblasts: 1125.1;Syncytiotrophoblasts: 1140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003677, HPA035330" Approved Approved "Nuclear membrane" NA NA 5000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nuclear membrane" "CAB003677: AB_425305, HPA035330: AB_2674574" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (9.70e-2)" "prognostic favorable (3.64e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.01e-5)" "prognostic unfavorable (1.64e-5)" "unprognostic (7.33e-3)" "unprognostic (3.09e-1)" "unprognostic (6.04e-2)" "unprognostic (6.49e-3)" "unprognostic (4.54e-1)" "prognostic unfavorable (9.29e-7)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (1.26e-4)" 490.6 286.5 111.7 241.7 126.3 96.2 314.0 136.9 144.7 429.1 137.7 181.9 96.5 288.7 162.6 135.1 225.0 273.1 213.9 106.4 134.7 216.2 149.5 299.0 136.2 151.2 129.6 224.7 162.9 133.7 176.7 466.0 150.4 211.7 155.5 78.1 273.8 250.5 85.2 132.5 130.9 370.3 134.3 175.7 186.0 110.4 154.3 63.3 182.9 114.8 135.2 298.1 178.6 157.3 463.5 339.6 438.0 256.1 2094.3 1645.5 503.4 1582.7 1464.9 841.3 744.8 246.2 200.6 35.7 282.9 2224.8 581.7 165.4 287.3 727.6 762.2 335.1 171.2 105.0 281.6 647.4 1213.9 221.1 178.3 945.5 344.7 705.1 665.9 927.4 1120.9 25.2 106.0 271.8 2133.5 306.7 225.5 75.1 231.9 417.7 718.5 8.2 1014.5 72.6 1368.9 66.3 117.1 141.4 579.7 227.6 1515.2 872.3 201.5 261.2 830.6 1322.1 632.1 955.2 478.0 240.8 308.6 76.0 847.8 123.5 1586.2 122.2 725.8 359.9 104.8 830.5 136.0 127.3 158.8 131.9 745.6 89.5 51.3 74.6 157.9 48.4 798.0 91.2 289.9 773.3 111.7 126.3 136.9 144.7 106.4 134.7 151.2 129.6 150.4 134.3 154.3 157.3 286.5 243.6 233.9 13.7 85.0 199.3 266.4 395.9 76.2 6.8 101.6 107.4 88.3 265.9 257.2 132.4 25.0 1156.8 53.2 15.6 297.4 703.5 16.2 239.7 318.1 287.7 48.6 29.0 15.4 338.2 1125.1 564.7 91.3 312.6 148.7 177.5 186.4 54.8 753.2 13.5 7.1 110.9 187.2 446.5 705.1 41.4 379.9 544.0 352.2 45.0 412.5 161.4 13.4 23.1 26.8 501.1 31.2 366.3 203.1 473.8 15.3 194.3 268.9 30.0 295.9 443.1 377.2 15.9 28.6 101.1 140.8 1140.8 122.0 185.7 43.2 188.2 ANXA6 ANX6 ENSG00000197043 "Annexin A6" P08133 5 151100706-151157785 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 343.8;monocytes: 445.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 861.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002462, CAB005077, HPA009650, HPA009977" Enhanced Approved Cytosol NA NA 1800000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005077: AB_630873, HPA002462: AB_1078166, HPA009650: AB_1844867, HPA009977: " "unprognostic (1.74e-1)" "unprognostic (5.85e-2)" "unprognostic (1.03e-1)" "unprognostic (5.81e-2)" "unprognostic (2.44e-1)" "unprognostic (9.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (9.63e-2)" "unprognostic (1.60e-2)" "unprognostic (1.08e-3)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.31e-5)" "unprognostic (6.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (1.38e-3)" 292.9 135.4 98.1 164.2 104.1 109.7 188.3 94.0 150.6 148.9 151.8 196.0 44.5 181.5 105.0 94.7 149.9 108.7 188.7 102.5 123.1 82.6 214.4 131.6 161.8 144.2 109.4 181.7 78.3 29.6 161.9 141.1 146.2 124.9 78.2 133.6 70.3 208.6 331.3 62.7 119.9 300.1 92.3 150.9 111.4 52.5 127.4 160.8 86.7 371.5 176.4 206.5 107.4 104.8 3.0 30.4 212.8 317.1 861.2 417.8 55.1 397.4 526.4 323.5 477.6 106.7 15.6 26.9 138.5 578.6 268.1 0.5 165.9 200.2 300.3 110.5 52.1 15.3 62.1 204.7 295.0 97.6 94.7 508.6 1.5 282.3 42.0 476.9 420.6 197.5 22.0 396.1 737.6 100.4 181.8 151.7 56.2 1.2 92.4 120.4 592.9 31.0 42.2 0.3 12.2 49.3 39.9 282.7 175.6 308.4 488.3 201.1 326.8 296.6 84.2 19.4 107.1 205.4 289.5 4.5 154.5 459.7 46.2 89.7 89.4 82.9 290.4 54.7 190.4 175.4 213.4 263.3 118.3 179.0 145.8 181.6 17.6 261.9 25.0 30.2 190.9 331.7 98.1 104.1 94.0 150.6 102.5 123.1 144.2 109.4 146.2 92.3 127.4 104.8 90.3 16.0 17.3 19.2 146.8 11.0 11.5 2.2 1.8 16.5 30.7 24.0 59.5 12.8 1.1 23.9 6.2 64.3 110.3 0.3 25.4 6.5 56.9 1.8 38.5 45.6 21.4 36.4 36.5 17.8 33.7 105.9 9.2 1.7 57.5 343.8 57.1 147.1 85.4 15.2 36.3 2.4 0.0 41.0 77.8 46.8 123.3 41.2 55.2 10.3 445.2 45.6 187.4 18.6 5.6 12.1 1.2 211.4 120.3 7.3 1.0 48.4 4.7 125.8 230.1 55.3 150.6 2.5 1.5 0.6 8.1 177.2 143.4 149.4 2.5 1.5 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase copper containing 2" O75106 17 42844580-42850707 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Early spermatids: 29.5" "Cancer enhanced" "Detected in some" "testis cancer: 3.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "ASC diff: 11.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA057779 Uncertain "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "HPA057779: " "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-4)" "unprognostic (1.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (4.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.64e-2)" "unprognostic (2.16e-2)" "unprognostic (8.27e-3)" "unprognostic (4.55e-5)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.47e-4)" 5.8 1.1 1.9 0.6 2.1 0.9 2.6 1.9 3.2 1.3 0.6 1.3 0.3 1.0 0.5 0.7 1.6 0.7 0.7 2.4 1.9 1.2 3.4 2.3 0.5 2.0 1.6 1.1 0.7 0.2 2.0 0.4 2.0 1.5 0.2 1.5 0.6 0.5 1.6 1.3 0.8 0.6 1.1 1.6 0.8 4.8 2.0 0.3 0.9 0.6 0.6 1.8 1.2 1.9 0.2 2.3 0.5 2.5 11.2 1.1 6.0 0.8 0.7 1.6 2.2 1.8 0.2 0.9 1.1 0.2 0.7 1.0 2.2 0.6 3.2 2.0 6.0 0.3 1.3 1.9 0.7 0.3 2.2 1.7 2.0 1.5 2.3 0.4 0.4 3.1 0.6 2.1 0.4 0.3 0.5 0.9 0.8 0.2 0.7 1.1 2.3 1.9 0.3 3.6 0.8 0.5 0.1 0.8 3.4 4.6 0.4 0.2 0.4 1.5 3.2 2.0 1.0 4.6 4.9 0.9 0.4 2.2 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.9 2.1 1.9 3.2 2.4 1.9 2.0 1.6 2.0 1.1 2.0 1.9 1.1 0.0 0.5 1.6 0.3 1.0 0.5 0.1 0.0 0.5 0.9 0.9 0.4 0.0 0.7 0.0 2.1 0.1 0.4 0.0 0.0 0.3 29.5 1.4 0.7 1.4 0.0 0.0 1.8 0.4 0.1 0.2 0.0 2.8 0.0 0.5 0.4 0.7 0.1 0.0 1.2 0.2 0.0 0.3 0.6 5.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.1 0.0 0.0 1.2 0.1 0.2 0.4 0.8 0.0 0.5 1.0 2.3 2.1 0.4 1.6 0.0 0.2 0.4 0.2 0.6 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 AP1M1 "AP47, CLAPM2" ENSG00000072958 "Adaptor related protein complex 1 subunit mu 1" Q9BXS5 19 16197854-16245906 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045256 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA045256: AB_10960697" "unprognostic (5.10e-2)" "unprognostic (3.71e-2)" "unprognostic (4.70e-3)" "unprognostic (2.85e-1)" "unprognostic (5.19e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-2)" "unprognostic (3.52e-2)" "unprognostic (2.08e-1)" "unprognostic (2.15e-1)" "unprognostic (1.37e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (1.02e-2)" "unprognostic (3.02e-1)" "unprognostic (2.96e-2)" "unprognostic (1.56e-1)" 49.5 47.2 30.1 30.7 31.0 58.5 37.9 22.3 36.3 32.2 22.0 37.7 32.1 38.8 9.2 29.6 29.8 21.4 39.9 33.0 31.0 39.6 81.0 31.9 36.9 26.6 30.0 31.7 18.8 20.1 24.0 27.5 33.5 25.3 12.6 17.3 21.6 24.8 44.4 30.8 31.0 35.4 23.1 37.6 27.3 60.8 25.0 37.8 23.7 29.0 28.2 38.3 29.1 25.9 63.3 70.2 69.3 65.3 82.7 80.9 39.1 69.6 74.1 99.5 103.3 83.9 48.6 49.8 78.7 76.6 64.4 35.1 54.2 56.9 111.3 85.5 122.3 80.9 63.4 114.6 67.1 91.5 96.9 83.5 42.2 89.2 59.8 65.4 95.6 69.8 40.3 98.0 109.5 75.8 131.2 55.4 56.9 22.3 162.7 87.9 56.7 67.3 54.9 45.2 44.4 99.4 56.8 34.4 64.0 36.9 41.0 73.1 83.1 111.8 45.6 151.7 134.3 104.6 141.6 54.9 125.5 112.8 88.7 89.4 142.3 243.9 104.8 180.7 105.6 99.8 103.4 111.2 121.6 92.3 115.1 147.0 101.8 133.1 235.7 131.2 161.8 174.3 30.1 31.0 22.3 36.3 33.0 31.0 26.6 30.0 33.5 23.1 25.0 25.9 17.4 41.7 31.2 12.7 30.6 4.6 7.4 13.2 11.4 35.4 11.3 10.9 17.9 14.3 15.2 12.9 20.9 32.1 30.5 8.3 15.6 21.1 32.5 10.6 27.2 22.7 19.8 21.7 11.8 18.2 40.4 28.1 8.6 14.8 27.1 19.0 21.8 41.9 42.6 42.1 11.7 7.3 6.1 36.0 13.3 92.1 23.0 30.2 10.6 5.6 34.9 18.3 38.1 4.5 12.8 31.2 5.9 19.9 24.5 6.2 25.1 23.6 13.9 40.2 0.0 26.1 22.8 61.9 23.3 12.6 7.1 17.5 32.9 17.7 9.0 4.6 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 259.8;Kupffer cells: 392.6;Langerhans cells: 609.2;Macrophages: 362.7;monocytes: 630.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cell line enhanced" "Detected in all" "Karpas-707: 298.0;SK-MEL-30: 442.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" 28.3 21.4 24.6 36.7 28.4 38.3 15.0 32.0 36.9 31.6 27.3 42.1 11.9 52.2 663.3 21.4 13.5 20.1 74.8 25.1 48.0 13.1 15.9 25.8 33.2 42.7 35.8 8.8 7.8 16.7 19.4 42.0 47.0 11.6 22.0 43.7 9.5 30.5 70.1 14.0 20.1 76.3 34.4 43.0 19.5 23.4 29.6 28.7 12.5 93.7 28.8 26.1 12.7 33.8 12.0 14.2 130.1 78.4 29.5 19.1 5.0 47.1 22.7 31.1 41.1 9.6 11.1 22.6 183.0 72.6 50.4 16.1 31.7 10.8 57.0 30.1 64.9 15.3 16.7 14.7 24.2 63.1 16.9 12.2 11.2 36.0 33.1 50.4 78.1 19.1 14.3 298.0 72.4 8.7 12.9 39.5 171.0 6.4 42.5 29.5 116.7 50.6 37.4 2.5 14.8 69.2 18.4 4.8 442.2 84.1 52.7 69.2 43.9 67.8 21.2 92.5 41.9 25.5 58.7 37.3 33.6 28.0 159.7 50.9 326.8 34.6 21.1 325.0 24.8 30.8 25.5 20.6 221.1 28.0 18.5 18.1 52.8 27.9 175.4 82.2 38.1 228.0 24.6 28.4 32.0 36.9 25.1 48.0 42.7 35.8 47.0 34.4 29.6 33.8 130.8 3.2 13.1 37.2 77.0 55.2 12.7 9.1 8.6 34.7 12.0 11.4 195.6 12.8 3.2 9.2 12.5 5.3 114.2 9.2 33.2 13.7 5.1 50.4 32.6 166.3 26.9 32.6 15.1 6.4 18.9 38.0 7.7 78.0 78.6 15.6 147.4 8.6 259.8 11.8 73.2 8.4 12.2 392.6 609.2 17.5 17.4 362.7 149.4 31.9 630.0 21.1 62.8 19.1 85.0 10.3 14.0 7.2 26.0 19.0 6.5 9.0 1.6 39.3 39.5 26.7 39.1 55.7 28.8 10.6 51.6 5.6 58.3 4.0 8.5 6.7 AP2A2 "ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899" ENSG00000183020 "Adaptor related protein complex 2 subunit alpha 2" O94973 11 924894-1012245 "Plasma proteins, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017514, HPA043040" Supported Supported Nucleoplasm,Vesicles NA NA 10000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "CAB017514: AB_2056344, HPA043040: AB_2678283" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.09e-2)" "unprognostic (1.28e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (9.27e-5)" "unprognostic (1.34e-2)" "unprognostic (4.09e-1)" "unprognostic (1.70e-1)" "prognostic favorable (4.57e-4)" "unprognostic (2.41e-1)" "unprognostic (2.86e-3)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (1.40e-1)" "unprognostic (2.08e-2)" 20.1 18.0 3.5 1.3 5.1 4.5 16.6 10.8 9.9 20.3 1.4 23.0 5.4 17.9 1.5 12.7 18.1 2.0 19.1 5.5 3.5 34.4 29.9 18.9 3.2 0.9 2.1 17.5 25.3 3.7 25.6 5.2 3.0 20.3 4.9 5.8 14.6 4.0 14.1 14.5 19.6 5.6 0.0 57.6 20.6 15.5 3.3 3.8 13.9 1.6 2.5 19.0 15.7 1.4 7.5 2.9 3.7 10.7 13.8 14.2 9.1 10.2 3.3 6.0 4.9 1.3 7.3 7.4 8.7 12.3 5.7 8.9 8.9 5.6 3.9 5.5 23.2 2.1 10.4 3.9 5.3 2.8 4.9 16.8 6.1 3.1 6.1 14.8 8.5 5.0 5.9 4.7 6.3 0.4 2.6 3.2 2.0 9.1 17.9 4.2 2.6 8.1 9.2 6.2 12.3 10.0 11.4 9.2 1.7 6.3 5.4 0.8 13.3 1.9 2.3 2.8 5.2 4.3 3.9 5.3 4.0 3.7 3.1 1.5 1.7 1.5 1.1 1.7 0.5 0.5 1.1 0.6 1.4 1.0 1.1 1.2 2.1 1.1 1.4 1.3 2.1 0.6 3.5 5.1 10.8 9.9 5.5 3.5 0.9 2.1 3.0 0.0 3.3 1.4 38.1 38.5 21.8 29.4 14.3 14.3 12.4 13.3 7.4 50.9 27.2 23.0 12.9 21.5 15.9 62.5 60.5 42.1 17.3 45.3 39.2 37.5 46.7 64.0 44.6 36.6 35.2 27.1 37.2 18.0 45.2 28.7 16.3 86.7 27.3 31.0 80.3 59.8 82.8 101.0 36.4 32.3 18.3 104.7 26.9 28.3 34.5 51.8 8.8 41.2 31.2 30.4 39.1 23.1 21.9 25.8 24.2 27.8 13.6 16.9 43.5 70.4 23.5 69.2 26.3 20.7 22.6 72.7 28.0 11.2 11.4 28.5 19.7 30.5 37.0 11.5 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 304.3;liver: 1191.0" "Group enriched" "Detected in some" 8 "Hepatocytes: 2967.4;Proximal enterocytes: 1585.9" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 1079.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793" Supported Supported Vesicles,Cytosol "Secreted to blood" NA NA 1490000000000 100000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "CAB016070: AB_626690, HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" 2.7 0.0 0.1 0.2 0.2 0.1 0.9 0.1 0.1 0.7 0.2 0.4 181.4 0.2 0.0 0.1 0.1 0.5 5.2 0.1 0.3 0.3 1191.0 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.1 0.5 304.3 0.2 0.2 0.5 0.3 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1079.8 0.0 0.6 0.1 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 277.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 1.6 3.5 0.0 104.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 52.8 2967.4 0.1 0.0 0.2 30.8 0.0 69.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.5 1.5 0.0 0.0 1585.9 0.6 0.0 0.0 0.0 1.1 0.2 0.5 0.3 0.0 0.0 0.0 3.9 0.9 14.5 0.0 APOBEC3D "APOBEC3DE, APOBEC3E, ARP6" ENSG00000243811 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3D" Q96AK3 22 39021113-39033277 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.3" "Cell type enhanced" "Detected in many" "B-cells: 6.7;NK-cells: 9.2;Plasma cells: 6.4;T-cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 11.8;Karpas-707: 46.7" HPA055116 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA055116: AB_2682701" "prognostic favorable (2.51e-5)" "prognostic favorable (1.31e-4)" "unprognostic (2.69e-2)" "prognostic favorable (4.47e-4)" "unprognostic (2.62e-2)" "unprognostic (3.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (2.45e-2)" "unprognostic (4.50e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (3.76e-7)" "unprognostic (4.76e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-2)" "prognostic favorable (3.01e-4)" 1.7 2.2 1.2 8.6 1.2 2.5 1.8 1.5 1.2 3.5 1.1 3.5 3.8 3.3 3.0 1.7 5.2 4.1 1.2 1.0 0.9 1.6 1.2 3.3 15.3 1.6 1.2 4.1 0.5 1.1 0.9 2.2 1.3 2.6 4.3 0.3 2.8 2.3 0.9 1.4 5.3 2.4 1.3 12.0 5.3 2.4 1.1 7.7 1.9 1.2 13.8 4.6 2.7 1.4 0.5 0.0 0.3 2.1 3.1 5.5 1.9 0.3 3.3 3.9 4.4 0.9 5.3 6.1 0.9 4.4 2.5 0.6 0.3 0.0 1.4 11.1 1.2 10.7 0.1 0.0 8.3 1.5 11.8 3.6 0.5 6.3 0.0 0.0 2.9 9.0 2.7 46.7 0.2 0.0 5.2 3.4 0.8 0.0 0.5 4.3 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.1 1.7 1.4 0.1 0.5 1.1 0.1 1.2 0.6 0.0 3.2 3.9 0.8 1.6 3.3 1.5 4.8 1.3 3.5 8.0 3.5 5.2 6.7 5.8 7.3 0.8 6.8 2.7 3.6 1.7 4.9 6.5 5.4 5.8 3.4 1.2 1.2 1.5 1.2 1.0 0.9 1.6 1.2 1.3 1.3 1.1 1.4 0.9 3.2 0.5 0.0 6.7 1.0 1.5 0.9 0.0 0.2 0.3 0.6 0.4 5.7 1.1 1.8 0.0 1.3 3.8 3.0 0.0 0.2 0.5 1.0 0.8 1.9 1.8 1.7 0.0 0.2 0.7 1.8 2.6 0.6 0.0 1.1 2.5 0.2 2.5 0.0 0.0 3.6 0.0 3.4 1.0 0.0 3.1 1.1 3.6 2.8 1.2 0.3 9.2 0.5 0.0 0.2 0.1 1.9 6.4 1.4 1.3 0.3 2.7 0.5 0.0 0.9 1.4 0.2 0.4 0.2 0.9 0.5 8.7 0.8 2.1 2.6 APOBEC3H ARP10 ENSG00000100298 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3H" Q6NTF7 22 39097224-39104067 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.6;dendritic cells: 9.6;Hofbauer cells: 4.9;monocytes: 10.5;NK-cells: 6.2;T-cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 9 "gdT-cell: 23.2;MAIT T-cell: 9.4;memory CD4 T-cell: 12.1;memory CD8 T-cell: 19.4;naive CD8 T-cell: 8.9;NK-cell: 19.7;T-reg: 11.9" "Group enriched" "Detected in many" 13 "NK-cells: 19.7;T-cells: 23.2" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HDLM-2: 2.7;Karpas-707: 6.9;U-266/70: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021492, HPA058565" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA021492: AB_10964888, HPA058565: " "unprognostic (7.09e-3)" "prognostic favorable (1.20e-4)" "unprognostic (1.05e-1)" "unprognostic (6.81e-4)" "unprognostic (3.40e-1)" "unprognostic (1.54e-3)" "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (3.83e-2)" "unprognostic (5.07e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.73e-12)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (6.55e-3)" "prognostic favorable (8.43e-7)" 0.7 0.8 0.3 2.3 0.5 3.6 0.6 1.0 0.7 0.7 0.0 1.8 0.5 0.8 3.6 1.1 1.3 1.6 0.5 0.3 0.3 0.8 0.6 2.4 3.8 0.7 0.4 0.5 0.3 0.6 0.7 1.0 0.6 0.7 3.3 0.6 0.9 1.5 0.6 0.5 1.2 1.2 0.2 3.1 0.9 1.6 0.5 2.9 0.7 0.0 2.1 1.4 0.6 0.5 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.0 0.1 0.2 0.0 0.0 0.2 2.8 1.0 0.3 0.0 0.1 0.0 0.6 0.0 2.7 0.3 0.7 0.1 0.0 0.2 0.0 2.0 1.8 1.6 0.2 0.2 0.2 0.0 0.1 0.0 6.9 0.9 0.9 1.4 0.2 0.0 0.0 0.0 1.6 0.0 0.2 0.0 1.3 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 4.8 0.7 0.2 0.2 1.2 0.1 0.1 0.3 0.0 23.2 0.5 9.4 1.4 12.1 19.4 0.2 0.4 0.6 8.9 0.0 19.7 1.6 0.0 11.9 4.7 0.3 0.5 1.0 0.7 0.3 0.3 0.7 0.4 0.6 0.2 0.5 0.5 0.4 0.0 4.2 0.0 1.6 0.1 0.6 0.9 1.2 0.0 0.2 0.3 0.1 0.0 2.4 0.0 0.0 6.6 9.6 0.1 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.4 0.3 0.0 0.6 0.1 0.5 0.1 3.8 0.1 0.4 0.2 4.9 0.0 0.2 0.0 2.0 1.0 0.6 0.5 0.0 1.0 0.0 0.0 10.5 0.0 6.2 0.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.9 0.1 0.2 0.2 0.0 1.5 20.8 0.0 0.0 0.5 APOL6 "APOL-VI, APOLVI" ENSG00000221963 "Apolipoprotein L6" Q9BWW8 22 35648446-35668404 "Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 46.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.9;NK-cells: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB028574, HPA029165, HPA029167" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "CAB028574: , HPA029165: AB_10670037, HPA029167: AB_10670832" "unprognostic (7.25e-3)" "unprognostic (2.67e-2)" "unprognostic (1.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.76e-1)" "unprognostic (1.55e-1)" "unprognostic (2.32e-2)" "unprognostic (8.29e-2)" "unprognostic (3.76e-2)" "unprognostic (6.26e-3)" "unprognostic (1.46e-3)" "unprognostic (1.46e-1)" "unprognostic (6.65e-3)" "unprognostic (2.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "prognostic favorable (6.61e-4)" 23.4 7.3 4.1 15.8 4.3 16.1 10.0 3.4 4.0 6.8 3.3 13.2 19.2 5.5 5.5 5.9 6.6 9.1 4.2 3.9 5.1 6.4 46.5 15.5 15.5 8.7 5.0 12.2 2.9 2.6 2.4 7.8 5.8 7.9 11.8 2.6 14.0 5.1 3.1 4.5 19.7 7.4 6.7 18.2 14.0 2.3 4.9 10.1 8.5 3.9 10.4 13.2 3.7 5.4 12.8 4.1 0.3 1.5 30.1 15.0 17.3 5.3 14.2 17.3 21.7 2.0 14.2 17.7 2.6 14.0 12.6 16.2 0.1 8.6 4.5 33.6 0.1 7.4 2.6 4.0 23.7 10.4 12.4 19.3 5.7 5.9 3.3 3.9 3.6 8.0 0.8 31.2 3.2 1.3 14.6 3.2 0.5 0.9 5.3 6.1 6.8 8.7 7.6 28.9 0.4 0.2 8.5 7.2 10.0 1.1 1.2 12.1 3.9 4.3 2.6 3.0 2.8 16.4 14.2 1.7 8.1 16.2 6.1 7.5 4.8 2.6 7.3 7.6 6.1 1.0 4.8 5.8 2.4 0.7 4.6 5.3 7.5 5.0 8.5 0.3 5.5 4.2 4.1 4.3 3.4 4.0 3.9 5.1 8.7 5.0 5.8 6.7 4.9 5.4 58.6 70.5 34.3 6.8 15.7 8.0 10.8 14.7 13.6 0.2 16.8 10.8 7.3 34.3 38.6 12.9 0.0 8.3 79.1 101.1 9.8 33.6 10.5 18.4 48.9 33.4 47.3 11.6 0.2 41.9 35.6 33.4 41.8 17.2 36.8 12.2 39.3 135.9 34.9 0.0 1.3 55.3 20.3 58.1 19.9 7.4 26.1 50.5 8.8 17.8 68.5 3.8 126.7 9.5 2.1 45.7 43.7 18.8 51.0 43.2 88.6 31.6 47.4 0.0 0.0 25.3 22.0 0.5 0.2 15.6 5.3 2.5 67.7 6.0 35.9 62.0 APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 124.5" "Cell type enriched" "Detected in many" 4 "Adipocytes: 781.6" "Cancer enhanced" "Detected in all" "renal cancer: 24.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 36.7;HDLM-2: 19.3;hTERT-RPE1: 15.1" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "HPA052462, HPA058882" Approved Approved "Nucleoplasm,Plasma membrane" No No "Cluster 6: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA052462: AB_2681841, HPA058882: AB_2683844" "unprognostic (1.98e-1)" "unprognostic (8.36e-3)" "unprognostic (5.28e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-2)" "unprognostic (5.58e-3)" "unprognostic (8.07e-2)" "unprognostic (3.46e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.23e-2)" "unprognostic (4.30e-3)" "unprognostic (3.42e-3)" "unprognostic (1.81e-1)" "unprognostic (6.18e-2)" "unprognostic (1.15e-2)" 124.5 15.6 35.2 15.4 28.7 0.3 90.6 29.8 41.8 43.8 22.5 12.4 3.9 15.7 2.3 35.3 30.5 34.4 55.8 26.9 30.7 20.0 17.7 17.1 5.6 37.6 34.0 6.9 24.0 28.0 10.5 86.6 38.1 12.8 12.0 5.8 10.3 5.6 34.3 18.4 10.7 52.5 30.3 6.1 12.1 3.0 43.6 10.6 64.8 28.8 3.3 28.3 18.1 29.3 6.4 0.2 36.7 1.2 1.1 2.1 0.3 6.0 9.9 6.0 8.7 2.4 6.5 2.0 0.5 2.3 2.1 2.0 1.4 0.3 10.1 19.3 1.4 0.5 2.0 0.0 2.2 1.0 0.6 1.4 1.7 2.1 4.7 15.1 4.6 3.5 0.5 2.5 3.1 1.3 1.0 1.1 0.2 1.5 1.1 2.9 0.8 0.9 0.7 0.6 3.1 3.4 5.7 0.5 13.6 0.6 0.2 3.1 5.6 1.3 2.0 8.1 5.5 1.8 0.9 1.4 2.0 4.0 6.9 2.2 0.3 0.2 0.3 0.1 0.4 1.0 0.7 0.5 0.2 0.8 0.5 0.3 1.6 0.3 0.2 0.6 1.1 0.1 35.2 28.7 29.8 41.8 26.9 30.7 37.6 34.0 38.1 30.3 43.6 29.3 781.6 6.4 5.3 17.3 15.9 18.1 2.5 1.4 6.8 4.4 5.4 5.8 11.9 4.3 5.9 0.0 4.2 2.9 13.3 5.3 0.0 1.1 2.9 0.7 7.2 169.4 3.6 18.9 5.3 0.4 1.4 25.0 1.1 1.3 7.6 5.8 62.4 3.8 6.6 3.3 7.0 6.3 2.0 14.2 27.1 2.1 4.4 6.6 28.4 32.8 5.9 39.6 29.9 5.0 28.5 1.2 0.6 0.4 5.7 2.9 2.3 0.5 5.4 4.8 111.7 17.5 193.5 5.5 1.0 2.3 15.5 1.0 18.3 1.1 9.3 3.7 AQP2 ENSG00000167580 "Aquaporin 2" P41181 12 49950737-49958878 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 92 "kidney: 386.9;seminal vesicle: 212.4" "Cell type enriched" "Detected in some" 440 "Collecting duct cells: 4143.6" "Group enriched" "Detected in some" 6 "renal cancer: 1.7;stomach cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.4;HEL: 1.1;HMC-1: 2.2;OE19: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA046834 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA046834: AB_2679830" "unprognostic (2.10e-1)" "unprognostic (3.77e-2)" "unprognostic (6.96e-3)" "unprognostic (4.48e-3)" "unprognostic (3.60e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (7.38e-3)" "unprognostic (5.92e-2)" "unprognostic (4.60e-2)" "unprognostic (2.01e-2)" "unprognostic (1.11e-1)" 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.0 0.0 0.2 1.5 0.0 0.0 386.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 212.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4143.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 9.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.1 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 622.6;testis: 222.0" "Group enriched" "Detected in many" 7 "Early spermatids: 1542.9;Late spermatids: 4265.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "OE19: 223.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" 2.9 0.8 2.7 0.1 3.7 0.2 17.1 3.3 2.7 12.9 1.5 0.4 15.3 2.7 0.2 16.5 0.7 2.8 4.0 2.4 2.9 1.9 0.1 7.6 0.0 3.3 3.9 0.2 2.0 3.0 1.2 0.0 3.1 1.3 0.0 1.0 622.6 1.0 0.2 112.7 0.1 0.3 2.6 0.4 52.3 222.0 3.8 0.0 1.6 0.0 0.1 0.3 0.4 2.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.7 223.2 0.0 10.1 0.0 0.0 0.3 0.0 0.2 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.7 3.3 2.7 2.4 2.9 3.3 3.9 3.1 2.6 3.8 2.6 0.5 57.7 3.1 0.0 0.1 1.3 0.5 18.3 0.0 0.8 53.9 48.0 0.3 0.0 56.4 7.3 0.0 0.0 0.1 0.0 0.0 0.1 1542.9 1.5 0.1 1.8 0.0 0.0 0.0 0.2 0.0 1.4 34.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 26.4 0.0 1.6 4265.6 28.6 1.7 295.3 0.0 0.0 53.7 0.0 3.0 0.1 7.2 0.0 19.2 0.3 1.6 0.0 0.0 9.7 1.7 19.7 0.0 1.8 403.9 15.9 1.3 0.9 0.0 0.6 18.7 0.0 0.6 AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 52.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Cardiomyocytes: 8.3;Collecting duct cells: 5.5;Ionocytes: 2.0" "Cancer enriched" "Detected in many" 9 "renal cancer: 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.4" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA015278: AB_10600982" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (9.53e-2)" "unprognostic (2.02e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-3)" "unprognostic (3.45e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.03e-2)" "unprognostic (1.77e-1)" 0.1 0.2 2.8 0.1 4.1 0.0 0.1 5.6 2.6 0.3 1.6 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.2 2.7 2.5 52.7 0.3 0.1 0.0 4.9 4.6 0.0 0.1 0.2 0.2 0.0 5.2 0.2 0.0 0.2 1.0 0.2 0.0 0.3 0.2 0.1 3.4 0.0 0.4 2.4 6.1 0.0 0.0 0.0 0.0 0.1 0.1 3.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 1.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.1 5.6 2.6 2.7 2.5 4.9 4.6 5.2 3.4 6.1 3.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.6 0.0 0.1 0.4 0.3 8.3 0.0 0.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 1.6 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.2 0.6 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AQP7 "AQP7L, AQP9, AQPap" ENSG00000165269 "Aquaporin 7" O14520 9 33383179-33402682 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 252.7;breast: 104.9;heart muscle: 108.5" "Cell type enhanced" "Detected in many" "Adipocytes: 129.7;Cardiomyocytes: 86.0;Early spermatids: 128.5;Proximal enterocytes: 160.7;Proximal tubular cells: 61.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 43 "ASC diff: 196.0" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.25e-2)" "unprognostic (3.81e-3)" "unprognostic (1.25e-5)" "unprognostic (7.22e-3)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (4.67e-2)" "unprognostic (3.06e-2)" "unprognostic (9.99e-2)" "unprognostic (4.65e-2)" "unprognostic (8.56e-4)" "unprognostic (1.21e-1)" "prognostic favorable (9.21e-8)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" 252.7 5.0 0.9 1.9 1.3 0.0 104.9 4.4 1.4 1.3 0.0 6.6 17.9 1.7 2.9 2.8 5.9 3.4 108.5 0.8 0.7 24.2 23.5 1.2 0.7 4.8 0.7 1.8 3.8 18.3 0.3 0.5 5.8 1.2 4.0 0.3 6.4 2.5 33.8 6.2 26.8 2.5 0.3 1.3 2.8 30.4 1.0 1.0 4.8 51.9 0.2 4.7 2.2 1.2 0.1 1.9 0.2 0.1 196.0 4.5 0.2 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.1 0.1 0.1 0.3 0.1 1.1 0.0 0.1 0.0 0.1 0.4 2.2 0.2 0.0 0.2 3.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 1.3 4.4 1.4 0.8 0.7 4.8 0.7 5.8 0.3 1.0 1.2 129.7 6.4 7.3 0.3 0.2 1.5 0.3 0.3 0.0 0.0 0.8 1.5 86.0 14.3 0.9 35.0 0.0 0.0 0.6 30.7 5.9 1.9 128.5 9.1 0.2 11.2 0.0 0.0 0.1 0.2 0.3 4.1 0.0 0.7 0.0 0.2 2.9 20.1 0.1 0.0 0.1 9.2 0.0 0.3 0.3 21.4 2.1 1.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.2 22.5 1.9 0.1 0.5 160.7 61.4 7.7 0.0 6.6 1.7 9.6 4.1 0.7 1.3 2.6 0.0 0.3 0.9 4.3 2.1 ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 33.2;Endothelial cells: 28.3;Hepatic stellate cells: 28.5;Horizontal cells: 38.7;Microglial cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 39.4;HUVEC TERT2: 74.3;TIME: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" 11.4 4.1 4.6 5.4 4.7 6.2 10.1 5.2 5.4 9.5 1.5 4.5 3.2 7.5 5.4 3.2 7.8 6.7 14.1 3.3 2.9 7.8 2.1 15.8 2.3 4.1 4.4 3.7 2.5 5.3 5.1 11.9 4.4 7.4 2.6 3.9 3.9 5.8 7.0 2.6 4.6 5.9 3.1 7.3 4.3 1.6 6.3 0.7 8.5 9.2 1.2 7.8 7.3 2.9 11.9 7.5 29.4 0.0 1.8 4.5 0.3 7.0 7.9 7.2 9.2 4.7 0.9 0.1 39.4 2.6 11.7 12.8 5.0 16.8 5.5 0.2 2.1 11.0 12.6 0.1 8.2 0.9 0.4 8.3 7.6 3.9 8.9 20.1 74.3 0.0 0.8 0.1 1.0 0.3 0.0 9.5 17.4 3.9 9.4 0.2 2.3 0.0 0.8 5.4 0.5 24.7 15.1 0.8 12.7 10.6 0.4 2.8 53.3 4.8 10.8 1.3 14.7 0.0 0.1 0.1 12.4 12.6 24.3 0.3 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.1 0.2 4.6 4.7 5.2 5.4 3.3 2.9 4.1 4.4 4.4 3.1 6.3 2.9 33.2 3.2 8.6 0.3 0.3 0.5 1.7 3.1 0.0 6.1 0.9 2.2 5.2 0.0 2.6 1.8 0.0 0.1 1.6 1.3 0.0 1.2 0.0 0.7 2.3 28.3 0.0 0.0 2.4 0.7 0.1 2.2 1.1 1.2 1.3 0.0 28.5 0.3 1.3 38.7 3.2 1.3 2.0 4.4 2.1 0.6 0.3 2.2 0.0 15.0 2.7 3.6 2.1 1.5 0.1 4.6 1.8 1.5 1.6 2.8 0.0 0.1 0.9 0.9 0.0 1.2 3.3 0.5 0.9 0.8 0.4 0.1 1.5 0.4 2.7 3.6 ARFGEF3 "BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33" ENSG00000112379 "ARFGEF family member 3" Q5TH69 6 138161939-138344663 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4;salivary gland: 18.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 114.6;Excitatory neurons: 200.9;Inhibitory neurons: 207.8;Oligodendrocyte precursor cells: 173.9;Oligodendrocytes: 378.1" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 14.8;RH-30: 13.4;RT4: 19.4;SK-BR-3: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036350 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036350: AB_10672084" "prognostic unfavorable (8.20e-4)" "unprognostic (4.31e-2)" "unprognostic (9.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.20e-2)" "unprognostic (4.53e-2)" "unprognostic (4.30e-3)" "unprognostic (1.21e-2)" "unprognostic (7.41e-2)" "unprognostic (7.82e-2)" "unprognostic (3.46e-2)" "unprognostic (4.93e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (2.38e-1)" "unprognostic (8.87e-2)" "unprognostic (1.69e-2)" 1.2 3.8 13.4 0.7 16.4 0.4 7.9 20.1 17.7 5.0 0.0 4.2 2.2 0.7 0.9 0.4 2.2 1.7 1.0 16.7 13.0 2.1 0.1 6.4 0.2 11.1 17.7 0.1 8.7 15.8 7.0 1.4 14.4 12.0 4.8 2.8 18.0 1.0 0.2 1.2 1.9 0.7 7.5 0.4 10.0 0.6 15.2 0.1 1.9 0.7 0.2 3.4 0.4 28.4 8.0 3.1 0.0 0.6 0.0 0.0 4.7 0.3 0.2 0.2 0.0 0.1 0.4 0.0 3.1 0.3 2.7 2.6 3.8 2.0 0.0 0.0 4.9 0.0 1.5 0.9 0.0 3.0 0.0 0.0 0.9 0.0 0.9 3.5 4.1 2.7 0.0 4.9 0.0 14.8 0.0 0.0 2.7 8.5 3.4 0.6 13.4 2.6 2.6 19.4 6.9 0.0 7.8 22.2 0.9 0.3 4.4 0.0 0.4 0.2 2.2 0.0 7.9 1.7 6.7 0.0 3.2 1.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.4 20.1 17.7 16.7 13.0 11.1 17.7 14.4 7.5 15.2 28.4 9.4 16.0 114.6 34.3 0.5 0.0 18.8 0.0 6.2 19.0 39.9 12.6 6.4 14.3 44.6 3.7 0.0 16.5 0.8 2.5 3.9 11.4 83.0 8.6 1.4 11.9 66.7 2.7 200.9 24.7 2.4 4.1 41.3 17.7 2.5 0.1 8.2 0.3 1.4 11.8 207.8 44.2 0.0 0.0 0.0 22.0 0.0 0.5 0.0 36.5 2.0 0.9 0.0 173.9 378.1 14.2 8.4 0.0 0.9 67.6 2.5 0.3 37.2 3.3 0.0 3.5 0.9 4.1 1.1 3.0 0.0 6.2 0.8 0.1 13.2 42.7 ARFIP2 POR1 ENSG00000132254 "ADP ribosylation factor interacting protein 2" P53365 11 6474683-6481479 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032985, HPA038156" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli fibrillar center, Golgi apparatus" "CAB032985: AB_2058811, HPA038156: AB_10697243" "unprognostic (2.32e-1)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "prognostic favorable (2.00e-5)" "unprognostic (8.44e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-3)" "unprognostic (2.50e-1)" "unprognostic (2.96e-1)" "unprognostic (1.76e-1)" "unprognostic (5.70e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.53e-4)" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (2.32e-2)" "unprognostic (9.48e-3)" 19.8 29.3 31.7 18.6 32.3 22.8 50.7 32.5 35.2 36.3 36.2 36.8 32.9 27.2 34.0 31.4 39.3 23.9 17.9 32.1 31.4 27.0 34.6 24.4 22.4 31.2 31.4 29.4 49.4 46.4 40.7 29.7 31.9 46.6 48.1 28.3 57.7 28.2 15.2 32.8 30.7 27.4 30.9 20.7 50.4 18.3 31.8 25.7 36.9 16.1 32.0 29.2 24.4 33.1 50.4 64.8 38.9 38.5 59.1 53.9 56.1 40.3 107.0 86.2 101.8 62.1 80.3 39.9 16.5 79.3 49.8 68.0 49.4 84.1 70.0 30.9 86.5 22.3 87.7 60.4 71.3 36.2 42.8 60.0 65.7 43.0 98.3 64.2 55.9 38.3 35.3 45.0 55.8 98.9 41.9 41.6 67.2 119.0 71.9 31.7 22.6 37.1 61.9 50.4 50.8 63.2 48.7 204.9 25.9 36.3 86.9 33.0 36.8 35.4 35.7 39.1 30.3 67.3 32.5 24.3 65.4 22.0 43.9 13.0 15.6 9.9 17.9 10.9 17.8 12.1 16.7 14.5 21.3 13.8 16.7 17.1 6.1 21.1 6.7 16.6 18.9 13.9 31.7 32.3 32.5 35.2 32.1 31.4 31.2 31.4 31.9 30.9 31.8 33.1 14.8 6.4 6.4 4.6 20.7 28.0 49.3 48.9 16.5 32.6 59.8 45.1 4.3 40.0 30.5 12.9 29.2 80.1 24.3 56.0 58.7 62.7 31.7 28.1 20.1 19.6 63.0 21.8 8.4 85.4 65.8 23.1 62.2 37.2 31.8 30.3 20.3 21.1 28.1 21.9 7.8 126.6 32.6 10.1 16.4 43.3 20.5 14.4 24.9 5.6 25.2 35.4 18.6 6.6 7.6 59.9 63.4 24.5 28.0 73.3 65.2 34.4 34.7 32.3 26.3 21.6 23.3 41.0 26.2 26.2 32.1 112.5 16.9 40.9 52.6 64.7 ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Approved Vesicles NA NA 11000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA004689: AB_1078194, HPA008285: AB_1078195" "unprognostic (1.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.05e-3)" "unprognostic (5.19e-2)" "unprognostic (2.48e-2)" "unprognostic (9.07e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.34e-3)" "unprognostic (1.24e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.94e-1)" "unprognostic (4.79e-2)" "unprognostic (4.13e-2)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (9.24e-2)" 84.5 49.2 40.9 38.0 48.3 33.4 61.8 33.4 46.1 71.3 31.2 62.8 25.7 93.7 21.5 75.0 68.4 50.7 112.3 39.1 41.0 41.5 46.2 38.4 30.7 45.7 43.2 46.4 36.5 24.7 36.8 39.0 39.0 64.9 32.6 9.6 46.1 62.6 30.0 65.3 46.7 80.6 38.0 58.4 49.0 15.8 49.8 23.2 44.6 20.5 34.6 107.9 63.4 57.4 23.0 56.7 27.9 39.8 135.4 99.6 32.9 50.3 50.7 45.3 41.2 34.2 29.5 33.1 26.7 102.3 40.7 55.8 22.4 76.0 33.5 23.3 24.6 36.8 27.7 40.4 44.5 31.3 52.3 131.9 46.7 34.5 42.9 46.8 39.1 27.1 24.3 30.3 55.9 82.6 21.2 30.9 72.1 78.5 29.4 25.0 39.9 49.3 42.3 85.2 10.0 31.6 45.8 69.8 19.1 40.1 88.0 35.4 49.1 82.1 25.5 98.7 51.0 32.0 38.2 24.8 77.4 52.0 39.3 27.6 33.0 33.1 26.7 56.9 19.3 14.3 20.8 22.8 32.3 14.7 17.9 20.8 37.3 23.7 72.0 34.1 27.4 24.9 40.9 48.3 33.4 46.1 39.1 41.0 45.7 43.2 39.0 38.0 49.8 57.4 25.2 19.2 18.7 16.6 18.3 8.5 13.4 24.6 10.8 11.9 22.3 24.6 50.2 10.0 18.1 29.5 27.1 25.1 35.2 35.2 3.9 22.2 0.4 17.9 26.9 19.6 19.4 15.3 13.0 27.9 31.0 29.2 31.6 27.6 19.6 21.3 25.7 32.1 30.4 16.8 15.3 36.0 14.2 30.7 8.4 1.7 23.6 19.1 8.8 11.2 28.2 11.0 36.0 23.1 92.3 27.3 19.2 35.3 10.1 11.4 22.4 13.3 10.9 14.2 59.2 28.0 55.9 3.1 3.5 24.7 13.1 16.6 19.9 9.4 21.5 18.7 ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.8;Astrocytes: 123.1;Endothelial cells: 46.9;Langerhans cells: 54.1;Microglial cells: 125.5;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 35.0;TIME: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA036380: AB_10673129" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (9.90e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.75e-3)" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-3)" "unprognostic (5.86e-2)" "unprognostic (1.30e-1)" "prognostic favorable (8.45e-4)" "unprognostic (3.57e-2)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (7.79e-3)" 17.0 2.1 8.3 7.6 9.3 0.8 9.0 10.1 8.3 6.0 1.1 5.4 3.0 6.2 3.1 5.9 5.1 8.6 13.0 8.3 8.9 4.9 3.6 19.5 5.6 11.6 10.4 6.1 2.9 4.0 2.1 11.2 9.4 3.0 5.4 1.5 2.8 3.4 4.2 6.4 4.7 11.8 9.0 7.1 3.2 1.3 10.8 6.9 12.7 9.2 6.8 8.1 3.8 9.9 0.4 2.5 6.2 12.2 3.5 2.9 1.9 7.5 8.6 5.8 4.2 0.1 0.5 0.1 8.7 19.5 10.0 0.2 5.9 1.9 6.7 11.0 0.8 1.7 0.8 0.0 5.8 0.4 7.0 7.8 0.2 15.1 1.7 4.5 35.0 1.2 0.0 3.0 13.1 0.2 0.1 0.3 2.1 0.0 7.6 0.0 2.9 0.0 1.7 0.0 0.0 22.7 3.8 0.0 15.6 3.3 0.7 0.6 38.5 16.0 6.4 2.0 5.9 5.1 5.6 6.2 10.9 5.6 16.4 0.0 2.6 0.0 0.4 2.8 0.8 1.6 0.3 0.5 6.0 0.6 0.3 0.2 0.0 1.1 1.1 5.2 0.8 1.2 8.3 9.3 10.1 8.3 8.3 8.9 11.6 10.4 9.4 9.0 10.8 9.9 47.8 19.2 24.6 123.1 7.3 5.2 0.7 3.1 1.8 0.6 0.5 1.7 16.0 1.5 3.1 0.0 0.0 1.2 9.8 0.2 0.0 2.1 0.4 0.4 2.1 46.9 0.0 7.4 3.4 2.0 10.3 7.3 0.0 0.4 9.5 8.4 30.7 0.6 10.1 0.0 18.4 3.9 0.0 14.5 54.1 0.7 2.8 16.7 10.6 125.5 13.8 3.9 4.1 159.8 0.9 1.9 0.3 2.6 4.9 1.1 0.0 2.1 1.4 0.4 0.0 2.5 11.3 0.3 0.7 1.3 5.1 1.0 3.7 3.3 0.4 0.7 ARHGAP40 "C20orf95, dJ1100H13.4" ENSG00000124143 "Rho GTPase activating protein 40" Q5TG30 20 38601934-38651035 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "breast: 32.4;epididymis: 35.7;esophagus: 28.7;skin 1: 45.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.7;Breast myoepithelial cells: 8.6;Club cells: 4.3;Collecting duct cells: 3.7;Early spermatids: 7.2;Late spermatids: 4.3;Respiratory ciliated cells: 3.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.3;HBEC3-KT: 13.6;RPTEC TERT1: 11.7;SK-BR-3: 12.7;T-47d: 15.4" "Not detected" "Not detected" "HPA042636, HPA042840" Uncertain Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" No NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA042636: AB_10962149, HPA042840: AB_10963929" "unprognostic (9.89e-3)" "unprognostic (2.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-3)" "unprognostic (1.69e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (5.63e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (2.89e-4)" "unprognostic (2.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.54e-1)" 0.1 0.0 0.3 0.0 1.3 0.0 32.4 0.1 0.6 3.2 0.2 0.0 1.7 0.7 35.7 28.7 0.1 0.1 0.0 0.2 0.3 5.6 0.1 0.8 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 0.8 4.6 0.0 0.0 3.6 7.9 0.4 45.3 0.0 0.0 0.2 0.0 4.6 2.7 0.6 0.0 0.9 0.0 3.7 3.2 7.4 0.2 4.5 0.0 0.0 0.0 0.0 0.0 8.3 0.1 0.0 0.0 0.1 0.2 0.9 0.0 3.6 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 12.7 0.0 1.6 15.4 0.5 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.6 0.2 0.3 0.3 1.8 0.8 0.2 0.6 0.2 0.1 0.0 1.5 0.7 0.0 0.3 0.0 1.8 0.0 0.0 14.7 8.6 0.1 0.0 4.3 3.7 0.0 0.0 0.2 0.0 0.0 0.0 7.2 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.4 3.4 0.0 0.0 0.0 0.3 0.7 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 ARHGAP5 "GFI2, p190-B, p190BRhoGAP, RhoGAP5" ENSG00000100852 "Rho GTPase activating protein 5" Q13017 14 32076114-32159728 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 381.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046993, HPA056507" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Cytosol" "HPA046993: AB_2679895, HPA056507: AB_2683158" "unprognostic (1.79e-1)" "unprognostic (2.03e-1)" "unprognostic (2.66e-3)" "unprognostic (6.77e-2)" "unprognostic (1.69e-1)" "unprognostic (3.75e-2)" "unprognostic (1.55e-2)" "unprognostic (6.23e-2)" "unprognostic (2.88e-1)" "unprognostic (2.18e-1)" "unprognostic (1.28e-2)" "unprognostic (6.63e-2)" "prognostic favorable (3.97e-8)" "unprognostic (9.79e-2)" "unprognostic (2.21e-1)" "unprognostic (2.13e-1)" "unprognostic (1.00e-2)" 23.7 27.3 54.3 19.8 55.5 10.9 27.3 66.4 53.6 26.2 12.1 29.5 35.3 28.0 24.7 66.5 23.2 32.7 62.8 47.5 52.7 43.0 31.8 28.0 14.6 42.9 52.0 47.3 29.7 48.1 10.0 37.1 43.2 30.5 26.3 57.8 59.8 29.3 14.0 30.8 38.9 23.4 45.6 42.9 29.4 46.5 50.6 18.3 68.5 24.7 18.5 32.8 15.7 80.4 61.0 48.5 47.3 69.8 60.7 42.4 27.3 37.1 45.6 22.1 32.9 62.2 58.0 17.9 32.1 47.0 37.2 63.3 46.0 39.9 42.7 18.0 26.6 26.9 30.1 91.2 41.5 16.5 15.5 47.5 78.8 20.7 77.1 54.3 27.4 33.3 24.3 51.8 36.3 31.9 36.4 0.8 23.7 67.1 57.7 38.9 58.2 3.5 48.4 159.5 73.2 28.6 99.6 52.7 74.6 52.5 54.8 1.1 44.6 40.8 60.6 33.9 27.6 19.7 41.5 2.8 20.5 17.5 113.1 2.2 1.4 0.0 3.1 0.7 3.8 6.1 5.5 3.0 5.3 5.3 5.7 3.5 0.5 5.9 1.2 7.6 5.0 2.0 54.3 55.5 66.4 53.6 47.5 52.7 42.9 52.0 43.2 45.6 50.6 80.4 50.9 192.3 71.9 381.9 40.7 94.2 144.2 52.1 130.9 97.2 52.8 53.3 301.2 58.6 70.2 58.8 114.7 27.5 27.0 85.0 54.8 50.2 42.0 92.1 77.9 42.9 61.8 28.6 81.7 46.1 14.5 65.1 59.7 136.3 5.1 30.0 37.5 51.1 19.0 65.6 140.7 56.8 46.8 19.0 45.4 66.8 104.4 44.2 67.6 65.6 18.6 103.3 14.4 139.7 205.6 75.0 93.5 100.4 35.7 104.2 89.6 60.1 78.4 92.7 59.2 103.1 65.9 128.5 75.6 94.0 70.3 13.4 29.2 77.3 51.1 180.9 ARHGAP8 "BPGAP1, FLJ20185" ENSG00000241484 "Rho GTPase activating protein 8" P85298 22 44752558-44862788 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 20.5;Cytotrophoblasts: 26.9;Ductal cells: 25.6;Pancreatic endocrine cells: 30.5;Urothelial cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.9;BEWO: 47.5;CACO-2: 30.9;HEK 293: 43.6;MCF7: 44.9;SK-BR-3: 40.1" "Not detected" "Not detected" HPA069694 Approved NA No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "HPA069694: AB_2686173" "unprognostic (4.14e-1)" "unprognostic (1.21e-2)" "unprognostic (6.88e-2)" "unprognostic (8.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-2)" "unprognostic (5.51e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" "unprognostic (8.78e-3)" "unprognostic (9.58e-2)" "unprognostic (7.65e-6)" "unprognostic (8.59e-2)" "unprognostic (3.29e-1)" "unprognostic (2.32e-2)" "unprognostic (2.22e-2)" 1.0 0.4 0.4 1.2 0.2 0.6 9.5 1.1 1.0 3.0 4.2 10.0 1.7 1.6 11.4 7.5 6.8 4.3 0.1 0.4 0.1 28.1 1.1 4.4 0.7 0.2 0.1 0.3 10.3 5.6 6.4 7.4 0.4 13.5 7.1 0.3 23.2 8.3 0.1 2.0 3.6 0.3 0.1 9.0 6.5 3.3 0.4 0.5 17.5 0.0 1.1 2.0 2.9 0.2 26.9 0.4 0.4 0.2 0.0 0.4 47.5 0.2 3.1 0.0 0.2 30.9 13.5 0.2 1.6 0.0 0.4 19.1 8.5 21.9 0.2 0.1 43.6 0.0 0.9 0.4 0.1 0.1 0.4 0.2 9.3 0.2 0.4 0.6 0.1 0.5 0.9 0.7 0.1 44.9 0.1 0.2 6.7 19.3 0.0 0.0 0.1 0.4 11.6 17.9 2.7 0.1 0.0 40.1 0.9 9.9 17.5 0.3 0.4 0.0 1.5 0.1 0.2 3.9 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.2 1.1 1.0 0.4 0.1 0.2 0.1 0.4 0.1 0.4 0.2 0.1 3.2 12.5 0.0 0.5 0.6 20.5 5.9 3.4 0.4 8.9 2.4 0.8 4.3 9.1 18.4 4.2 26.9 0.7 8.6 0.0 25.6 2.3 4.1 1.0 1.1 7.2 0.0 0.0 10.8 2.1 1.3 7.1 12.3 0.0 0.5 0.4 0.0 3.3 0.0 0.0 11.7 12.2 1.0 0.4 3.2 0.3 0.6 0.0 0.0 0.1 0.7 5.2 0.0 0.0 30.5 12.1 0.4 0.6 20.0 1.2 2.0 4.1 0.7 0.0 1.7 0.7 0.1 3.9 6.0 0.3 7.0 1.0 6.9 17.0 20.8 ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "dendritic cells: 171.0;Early spermatids: 96.8;NK-cells: 123.6;Spermatocytes: 89.0;T-cells: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 388.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 27.6;HMC-1: 116.2;MOLT-4: 22.5;NB-4: 22.1;THP-1: 34.9;U-937: 27.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (1.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.91e-2)" "prognostic favorable (6.61e-5)" "unprognostic (1.24e-1)" "unprognostic (2.38e-3)" "unprognostic (4.79e-2)" "unprognostic (5.56e-3)" "unprognostic (1.28e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.90e-9)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" 10.8 4.2 4.2 34.3 6.1 119.7 4.1 8.1 11.1 2.6 4.7 7.7 8.2 3.4 1.6 4.6 7.4 10.5 3.9 4.4 5.3 5.1 7.5 22.0 56.9 7.8 5.8 1.6 3.5 0.6 2.2 5.2 8.8 4.3 10.7 0.5 4.7 1.8 1.3 2.2 37.6 5.9 5.6 100.7 8.8 19.3 6.1 34.9 4.5 6.4 60.7 9.5 3.6 6.4 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.4 0.5 0.1 0.2 0.1 0.0 14.3 0.3 0.3 0.0 0.2 0.4 0.0 0.0 0.7 0.0 27.6 0.1 0.0 1.1 16.4 116.2 0.7 0.0 0.0 0.3 0.2 0.0 14.3 0.5 7.9 0.0 0.0 22.5 22.1 1.0 0.0 0.0 9.1 10.2 4.6 0.0 0.1 3.9 3.0 0.0 0.0 0.4 0.5 0.0 34.9 0.9 0.2 0.3 0.1 0.1 9.2 7.2 13.3 0.3 27.3 0.5 51.9 86.1 243.4 43.3 89.2 30.0 35.9 47.3 39.6 72.1 44.0 61.9 46.0 388.9 68.2 71.0 97.4 63.6 70.8 4.2 6.1 8.1 11.1 4.4 5.3 7.8 5.8 8.8 5.6 6.1 6.4 2.2 0.0 14.2 1.0 49.1 1.5 0.2 0.0 1.8 0.2 1.6 2.9 2.1 1.5 1.3 0.0 2.1 0.4 171.0 0.6 0.0 0.2 96.8 0.6 0.8 1.5 0.0 11.6 3.7 0.0 0.6 2.4 4.6 0.8 12.0 0.0 3.6 1.2 43.5 0.0 1.9 0.5 0.0 39.0 19.7 44.8 1.8 35.1 0.0 8.4 34.8 0.0 123.6 0.0 0.2 0.2 0.1 0.0 50.8 0.2 0.0 0.3 2.2 0.7 0.0 0.6 1.2 89.0 17.5 0.4 1.4 0.3 108.2 0.3 0.4 0.1 ARHGDIG RHOGDI-3 ENSG00000242173 "Rho GDP dissociation inhibitor gamma" Q99819 16 280450-283010 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 249.4;pancreas: 112.7" "Cell type enhanced" "Detected in some" "Astrocytes: 12.1;Excitatory neurons: 27.8;Inhibitory neurons: 32.1;Proximal enterocytes: 64.0" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.6;HEK 293: 26.6;MCF7: 34.9;SCLC-21H: 10.9;SH-SY5Y: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078260 Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA078260: AB_2732375" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (7.98e-2)" "unprognostic (2.66e-2)" "unprognostic (9.04e-2)" "unprognostic (2.13e-2)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-2)" "unprognostic (3.18e-1)" "unprognostic (2.94e-1)" "unprognostic (5.86e-6)" "unprognostic (2.81e-2)" "unprognostic (4.34e-1)" "unprognostic (2.15e-1)" "unprognostic (6.32e-2)" 4.5 2.8 116.5 1.1 138.7 0.2 1.3 118.2 249.4 0.5 49.9 5.9 16.7 0.1 0.9 0.5 0.5 0.1 10.2 130.1 121.2 0.3 0.2 0.5 0.0 110.3 106.1 0.3 112.7 0.6 10.1 2.2 109.8 0.9 0.4 4.0 0.4 0.3 1.9 0.2 6.9 0.6 84.9 0.1 26.8 3.6 112.6 0.0 0.3 1.4 0.4 0.4 1.1 134.9 0.0 0.8 0.2 2.9 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.9 0.1 0.0 0.1 7.6 0.0 0.0 0.0 26.6 0.0 0.4 0.2 0.7 0.0 0.1 0.2 0.0 0.0 0.0 1.3 0.3 0.0 1.8 0.1 0.0 34.9 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.3 0.0 0.0 10.9 13.9 0.2 0.1 0.0 0.4 2.6 0.0 0.3 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.5 138.7 118.2 249.4 130.1 121.2 110.3 106.1 109.8 84.9 112.6 134.9 0.1 0.0 0.0 12.1 0.0 0.4 0.0 0.0 0.0 4.0 0.0 0.3 1.4 0.0 0.0 0.0 2.1 0.1 0.0 0.7 0.0 0.2 0.4 0.0 0.4 0.1 1.2 2.7 27.8 11.7 0.2 2.5 6.1 0.0 0.0 0.2 1.4 0.0 0.4 0.0 32.1 3.7 0.0 0.0 0.0 0.6 0.3 0.0 0.0 8.4 0.0 2.2 0.0 6.6 10.9 3.9 3.9 0.0 0.0 0.1 64.0 0.1 0.0 3.7 0.0 0.0 0.4 0.2 3.9 0.0 0.0 0.4 0.0 0.0 7.0 0.1 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARHGEF16 "GEF16, NBR" ENSG00000130762 "Rho guanine nucleotide exchange factor 16" Q5VV41 1 3454665-3481113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.1;Extravillous trophoblasts: 55.6;Gastric mucus-secreting cells: 67.2;Intestinal goblet cells: 49.6;Paneth cells: 68.2;Proximal enterocytes: 72.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.4;MCF7: 32.4;OE19: 38.2;SK-BR-3: 34.9" "Region enhanced" "Detected in many" "olfactory bulb: 4.7" "Low region specificity" "Detected in many" HPA010609 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA010609: AB_1845004" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (4.31e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (5.39e-2)" "unprognostic (9.16e-2)" "prognostic favorable (1.24e-10)" "unprognostic (6.46e-2)" "unprognostic (2.86e-1)" "unprognostic (1.71e-2)" "unprognostic (3.29e-2)" 3.8 0.5 1.4 2.7 2.0 0.0 4.8 3.0 2.0 3.5 5.2 19.7 44.0 1.1 2.7 17.9 2.5 11.1 1.0 1.1 4.0 17.7 6.5 3.3 0.2 5.3 2.6 1.3 11.1 8.0 11.4 5.0 5.1 9.4 11.9 2.7 17.0 5.7 1.4 5.9 34.2 0.5 2.6 0.8 28.1 3.2 3.3 0.4 10.0 1.5 2.0 5.0 9.0 3.3 18.3 6.8 1.8 0.2 0.0 0.0 12.6 0.3 0.4 0.5 1.4 20.7 56.4 0.0 13.5 0.1 3.4 18.8 3.0 12.1 0.1 0.0 6.3 0.0 8.8 16.2 0.6 0.0 0.1 0.3 11.4 1.2 0.6 1.2 0.1 0.3 2.3 0.0 0.1 32.4 0.0 0.4 13.8 38.2 0.4 0.0 0.0 2.7 14.2 9.1 9.8 1.8 3.6 34.9 0.8 7.1 15.7 0.6 0.0 0.2 4.0 0.3 0.4 0.1 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.0 3.0 2.0 1.1 4.0 5.3 2.6 5.1 2.6 3.3 3.3 0.6 9.6 5.4 2.0 0.5 3.2 15.0 9.1 14.2 1.1 8.1 4.6 1.6 12.8 11.7 16.5 6.2 3.2 0.1 101.1 15.6 16.5 0.1 4.3 0.8 0.8 10.2 0.0 0.4 12.7 55.6 0.8 67.2 9.9 0.0 17.3 0.4 4.3 1.2 3.3 0.5 49.6 20.3 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.6 36.7 0.0 0.5 5.2 28.6 68.2 0.0 2.8 3.6 72.1 11.5 6.5 8.8 0.0 0.0 3.0 0.3 3.9 12.2 1.0 6.7 0.5 2.0 40.0 13.3 ARHGEF37 FLJ41603 ENSG00000183111 "Rho guanine nucleotide exchange factor 37" A1IGU5 5 149551947-149634968 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 36.8;Oligodendrocytes: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 9.3;neutrophil: 3.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 9.3" "Cell line enhanced" "Detected in many" "EFO-21: 13.9;HaCaT: 26.1;hTCEpi: 33.8" "Region enhanced" "Detected in many" "cerebellum: 10.4" "Low region specificity" "Detected in all" "HPA043885, HPA053487" Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "HPA043885: AB_2678715, HPA053487: AB_2682167" "unprognostic (3.51e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-1)" "unprognostic (3.92e-1)" "unprognostic (1.17e-1)" "unprognostic (6.87e-2)" "unprognostic (1.54e-3)" "unprognostic (1.54e-1)" "unprognostic (2.64e-1)" "unprognostic (6.93e-2)" "unprognostic (2.13e-3)" "unprognostic (1.16e-2)" "prognostic favorable (6.85e-4)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.50e-2)" "unprognostic (2.10e-1)" 4.2 3.8 26.9 2.2 38.9 5.2 24.5 33.3 33.8 5.5 34.0 20.8 6.8 7.4 13.6 14.0 10.6 6.3 12.1 23.4 28.6 9.1 2.5 6.4 1.5 41.1 35.9 3.8 10.7 28.1 6.7 3.2 39.5 23.3 7.5 14.4 39.9 35.4 20.4 45.1 7.4 10.2 32.5 1.4 23.3 5.5 35.3 1.6 2.9 10.5 4.8 10.6 8.9 51.3 4.4 1.7 1.2 5.1 0.3 0.6 3.0 0.5 0.9 0.8 0.8 0.0 5.6 0.6 13.9 0.6 1.5 26.1 0.4 2.6 1.6 1.1 1.3 0.4 2.9 0.3 1.0 0.0 0.8 0.7 33.8 2.6 3.3 2.7 4.2 1.8 0.6 1.1 0.0 0.6 0.8 0.8 0.3 10.7 3.1 0.5 0.6 0.0 5.7 2.1 2.1 5.0 3.2 0.3 0.5 0.6 7.7 0.1 3.4 0.3 0.9 0.1 0.7 0.7 1.6 0.5 1.0 0.1 3.6 9.3 0.5 0.3 0.2 0.8 0.3 0.1 0.1 0.2 0.2 0.4 0.5 0.4 3.0 0.2 0.3 0.7 0.1 0.0 26.9 38.9 33.3 33.8 23.4 28.6 41.1 35.9 39.5 32.5 35.3 51.3 9.2 0.0 4.5 5.9 2.8 6.8 9.6 10.4 0.6 4.6 32.7 24.4 15.8 17.2 16.5 9.2 4.2 6.2 4.6 18.2 0.0 3.7 5.3 9.4 2.0 7.4 11.4 14.3 5.1 4.9 1.4 2.7 9.7 9.9 7.0 1.7 6.8 3.2 3.1 5.0 7.5 9.6 8.2 2.5 3.3 1.5 1.8 2.9 3.6 12.2 3.9 36.8 7.2 2.0 62.3 5.1 10.1 10.5 2.0 10.5 15.9 1.4 17.8 7.6 6.6 5.7 4.5 16.0 5.7 4.8 9.7 4.5 3.3 1.5 10.5 5.7 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "U-698: 397.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Nuclear bodies" "CAB004318: AB_626698, HPA001759: AB_1078213" "unprognostic (1.81e-1)" "unprognostic (8.14e-2)" "unprognostic (6.87e-2)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (9.43e-2)" "unprognostic (5.27e-3)" "unprognostic (5.05e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (9.52e-2)" "unprognostic (1.85e-3)" "unprognostic (2.68e-1)" "unprognostic (4.67e-1)" "unprognostic (6.45e-2)" "unprognostic (6.92e-2)" 25.8 20.4 9.6 18.1 9.6 17.1 22.7 16.2 12.2 31.8 16.5 19.5 15.0 27.4 14.8 19.2 25.0 20.5 20.7 8.9 10.7 17.8 42.9 24.7 17.5 10.4 9.5 37.7 28.6 19.6 12.5 31.2 10.2 16.3 21.2 39.1 15.5 17.6 32.3 23.9 17.0 29.0 8.0 19.5 19.0 17.3 10.9 20.4 19.6 28.1 22.4 21.3 24.0 11.2 17.1 17.2 25.6 19.5 53.4 50.9 34.2 19.0 36.9 25.2 22.7 15.1 17.0 18.3 16.5 34.0 12.4 19.1 24.2 21.3 21.9 29.3 13.8 21.4 28.7 17.6 31.0 26.4 24.7 39.9 20.0 30.7 26.9 30.6 31.3 24.4 27.9 34.9 26.3 33.8 21.1 15.0 21.2 30.9 13.0 26.1 30.8 25.5 20.6 17.4 17.6 25.1 36.6 25.3 15.2 34.4 32.6 59.4 22.6 20.9 18.8 16.8 16.8 39.8 30.8 397.5 25.5 0.9 14.4 46.6 23.6 21.2 12.1 21.6 11.1 8.7 10.0 11.7 18.7 8.7 9.5 9.8 11.9 12.0 23.4 7.8 11.1 16.2 9.6 9.6 16.2 12.2 8.9 10.7 10.4 9.5 10.2 8.0 10.9 11.2 14.8 12.8 10.3 28.1 14.9 14.1 9.9 11.0 8.0 23.6 10.2 6.9 12.8 24.3 11.6 11.0 54.2 24.5 12.6 13.3 3.9 11.2 5.0 10.3 23.3 14.8 20.4 16.6 41.6 9.7 37.1 25.4 8.6 20.6 3.8 17.1 30.0 47.7 20.3 6.7 47.5 16.5 8.2 39.1 20.1 4.3 32.3 20.0 10.6 39.4 27.9 7.9 13.4 41.7 50.9 9.6 8.1 32.7 13.0 8.8 10.1 13.1 9.7 38.3 13.1 17.0 19.4 18.4 16.7 11.0 15.3 29.6 12.7 20.7 9.0 10.0 ARPIN "C15orf38, MGC61550" ENSG00000242498 "Actin related protein 2/3 complex inhibitor" Q7Z6K5 15 89895006-89912952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 5.3;intermediate monocyte: 2.9;myeloid DC: 4.5" "Group enriched" "Detected in many" 6 "dendritic cells: 4.5;monocytes: 5.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040513, HPA047173, HPA052278" Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "HPA040513: AB_2677015, HPA047173: AB_2679969, HPA052278: AB_2681783" "unprognostic (2.63e-1)" "unprognostic (1.09e-1)" "unprognostic (4.35e-2)" "unprognostic (5.01e-2)" "unprognostic (2.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (7.46e-2)" "unprognostic (2.67e-3)" "unprognostic (1.75e-2)" "unprognostic (1.57e-1)" "prognostic favorable (4.19e-4)" "unprognostic (8.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.23e-1)" "unprognostic (6.62e-3)" 10.6 4.7 9.3 7.0 10.1 0.9 8.4 11.2 8.5 11.4 5.4 15.0 14.5 11.9 13.9 10.3 11.5 8.1 8.1 8.1 9.7 7.5 5.2 11.9 4.6 10.8 9.3 14.7 40.0 12.9 5.0 8.6 9.7 12.6 16.7 9.5 9.0 11.3 9.5 12.2 16.9 11.5 9.3 7.7 8.0 6.0 10.5 3.3 8.7 8.1 5.4 9.5 10.7 10.4 13.9 18.5 18.6 12.3 10.9 14.9 3.5 12.8 9.5 8.5 9.6 2.6 18.8 0.1 6.3 11.6 3.4 6.4 0.1 12.6 7.6 0.1 4.6 0.1 22.1 3.5 7.2 0.1 1.2 9.7 12.2 10.2 2.1 6.5 14.9 0.1 0.1 0.6 11.1 2.8 0.0 0.3 7.5 11.6 2.1 0.0 0.5 0.1 4.5 13.2 0.6 6.1 28.1 11.4 14.5 9.9 22.4 3.8 10.3 15.8 17.6 20.3 6.4 0.3 0.1 0.2 13.1 0.1 5.9 0.5 5.3 0.1 0.1 2.9 0.3 0.1 0.1 0.0 4.5 0.2 0.1 0.1 0.7 0.2 0.4 0.3 0.0 1.3 9.3 10.1 11.2 8.5 8.1 9.7 10.8 9.3 9.7 9.3 10.5 10.4 14.8 25.6 21.0 0.0 1.0 0.0 16.2 0.0 11.4 9.5 11.1 10.3 10.2 22.8 8.1 16.5 12.5 16.1 0.3 19.0 3.9 10.0 33.3 13.0 11.8 13.2 12.2 1.7 0.0 15.8 17.5 13.6 9.2 10.9 6.3 15.7 13.2 13.4 24.4 5.0 0.0 18.3 0.0 26.6 0.0 109.0 15.2 18.5 0.0 0.0 23.0 14.0 0.0 0.0 0.0 12.8 23.8 17.0 0.2 12.5 50.6 19.2 5.1 15.4 13.1 18.3 11.9 20.2 5.7 18.2 0.0 6.7 0.8 6.4 20.6 12.1 ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 262.0;Kupffer cells: 242.5;Langerhans cells: 164.2;Macrophages: 226.4;monocytes: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 195.8;HMC-1: 315.9;NB-4: 199.2;U-937: 279.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" 48.6 39.7 54.4 110.0 53.8 263.6 26.1 48.2 62.2 19.3 49.1 29.5 50.5 17.4 10.8 15.1 29.0 31.4 25.0 63.8 67.7 25.2 35.6 94.8 59.4 61.6 58.3 17.5 19.4 16.4 24.9 35.5 59.5 19.5 27.6 16.9 20.9 11.7 12.7 14.6 51.1 29.6 55.4 168.3 35.0 7.2 59.5 45.2 15.8 18.1 38.0 41.6 17.6 66.5 17.3 88.7 34.7 32.9 6.8 9.5 18.6 13.7 18.0 38.4 48.0 31.0 14.2 49.1 12.2 10.3 18.3 28.5 58.0 18.4 39.4 116.6 85.0 195.8 46.8 55.6 10.2 89.2 315.9 8.8 23.5 47.9 18.7 24.9 29.6 89.1 13.5 46.4 8.9 30.5 87.9 199.2 18.9 44.9 18.4 104.3 31.0 53.8 13.2 9.2 36.0 49.2 30.8 50.8 23.6 14.2 24.6 40.0 26.1 14.3 29.1 25.1 51.5 19.8 28.6 27.6 37.9 279.4 21.6 116.2 145.5 269.7 49.1 151.1 35.1 10.1 31.1 51.3 84.9 9.0 29.3 38.7 250.6 29.9 168.6 20.7 28.8 93.5 54.4 53.8 48.2 62.2 63.8 67.7 61.6 58.3 59.5 55.4 59.5 66.5 7.7 22.4 32.3 5.5 26.4 11.5 7.7 16.6 3.4 20.5 9.6 12.3 8.3 14.3 47.9 3.7 2.1 7.5 83.8 7.4 15.6 11.2 0.6 1.5 3.6 10.1 8.4 33.9 20.4 7.3 12.0 8.7 19.4 1.8 94.9 7.8 19.2 12.4 262.0 21.9 18.2 17.0 50.8 242.5 164.2 3.5 5.0 226.4 10.6 42.2 311.3 5.8 89.6 7.1 8.4 6.3 22.0 4.9 23.4 4.4 35.5 17.5 24.4 8.7 19.7 10.9 8.5 1.1 13.1 6.8 8.4 6.0 77.2 3.5 11.4 11.7 ARRDC1 MGC40555 ENSG00000197070 "Arrestin domain containing 1" Q8N5I2 9 137605685-137615360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 204.5;T-47d: 89.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044345 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA044345: AB_10965181" "unprognostic (3.25e-2)" "unprognostic (1.41e-2)" "unprognostic (6.03e-3)" "unprognostic (4.32e-3)" "unprognostic (8.21e-2)" "unprognostic (8.01e-2)" "unprognostic (7.95e-2)" "unprognostic (2.65e-2)" "unprognostic (2.37e-1)" "unprognostic (1.26e-1)" "unprognostic (3.55e-1)" "unprognostic (5.52e-2)" "prognostic favorable (3.59e-4)" "unprognostic (5.01e-3)" "unprognostic (1.51e-1)" "unprognostic (8.70e-2)" "unprognostic (1.11e-3)" 19.8 25.2 8.7 9.1 8.8 23.3 28.3 7.4 15.1 23.7 11.4 39.0 22.7 13.1 3.2 60.4 21.5 4.6 23.9 9.4 8.0 35.7 42.9 35.2 11.0 9.3 8.3 10.3 42.9 9.5 30.8 7.8 9.2 43.4 5.3 3.1 51.9 11.2 13.6 37.2 43.8 2.5 8.2 54.6 53.7 21.0 8.5 8.3 31.7 4.0 4.9 23.6 35.9 8.4 39.4 25.4 2.4 8.3 3.9 4.2 38.7 10.2 8.8 5.5 4.2 21.4 53.1 9.5 25.7 7.2 10.5 79.5 2.8 32.9 0.9 8.9 15.6 6.4 23.1 19.4 9.3 11.2 15.4 1.7 49.2 4.9 20.4 7.4 7.9 14.7 13.8 5.6 2.4 204.5 13.6 72.0 5.1 43.9 31.6 16.3 4.2 43.1 20.4 29.2 10.3 7.8 7.1 83.0 11.4 2.5 89.9 26.5 18.8 3.2 4.7 21.8 8.8 11.1 9.0 8.3 8.5 24.9 3.7 108.7 99.2 214.7 35.7 132.5 26.4 23.3 32.7 32.8 121.8 39.9 28.9 28.4 92.9 28.3 122.3 46.1 49.7 56.1 8.7 8.8 7.4 15.1 9.4 8.0 9.3 8.3 9.2 8.2 8.5 8.4 39.4 19.2 22.3 11.1 29.2 17.0 58.5 78.0 29.0 7.2 52.5 35.3 5.4 45.8 67.1 58.8 62.6 85.4 43.1 71.7 37.2 50.2 12.1 30.9 8.2 22.5 17.4 11.1 10.6 46.0 41.8 10.1 85.6 32.9 18.4 22.1 23.2 23.7 48.1 3.3 6.1 56.1 57.0 54.0 29.8 14.8 10.8 41.3 7.2 16.9 57.0 10.7 46.4 2.5 3.5 69.1 72.8 10.5 20.6 58.6 81.6 27.4 53.9 46.0 0.0 4.1 13.7 21.3 13.7 33.7 21.3 73.3 38.8 6.7 47.1 69.0 ARSD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.2;EFO-21: 24.5" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA004694: AB_1078221, HPA063835: AB_2685132" "unprognostic (3.92e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.21e-4)" "unprognostic (5.90e-3)" "unprognostic (6.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (4.09e-3)" "unprognostic (7.18e-2)" "unprognostic (3.93e-1)" "prognostic favorable (1.97e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (4.99e-2)" "unprognostic (2.11e-3)" 8.4 7.8 4.3 6.1 4.1 4.9 23.6 4.2 4.5 23.9 10.7 20.5 21.0 11.2 15.9 10.0 28.0 11.4 4.8 4.1 5.1 38.9 40.0 16.8 3.6 6.3 5.7 18.7 32.4 12.7 4.2 8.6 5.4 19.3 14.8 1.7 17.5 13.3 1.7 7.3 15.4 7.6 5.6 7.2 30.4 3.8 4.6 2.8 21.1 3.2 4.2 11.7 8.4 5.0 6.9 12.0 3.2 15.4 13.6 7.7 0.1 3.9 7.1 1.7 1.1 0.7 23.2 0.0 24.5 7.9 18.1 0.0 0.6 2.0 1.6 0.2 0.0 0.0 0.0 4.0 7.5 0.0 9.1 12.3 6.3 3.4 3.6 11.1 11.5 0.0 0.0 0.1 7.6 16.9 0.1 1.7 2.7 21.3 5.0 2.9 0.0 0.2 12.3 0.1 0.0 8.5 5.4 6.3 4.1 8.5 17.1 13.1 10.6 0.0 0.5 1.2 1.8 0.1 0.0 0.0 11.1 8.2 8.8 1.5 5.8 4.1 1.7 5.0 0.6 1.3 0.8 1.4 4.4 0.8 0.2 0.9 1.0 2.0 2.0 3.0 0.3 2.5 4.3 4.1 4.2 4.5 4.1 5.1 6.3 5.7 5.4 5.6 4.6 5.0 13.4 19.2 36.4 9.8 4.5 5.0 13.9 11.3 10.8 4.9 45.0 30.9 5.6 74.4 23.1 44.1 0.0 19.1 8.6 44.3 19.6 35.1 0.7 68.6 19.6 13.8 67.9 3.4 0.9 53.9 25.0 7.9 31.6 67.8 16.5 66.8 11.7 109.9 18.5 0.0 1.7 56.2 10.2 17.8 6.4 1.4 6.2 16.1 14.2 6.5 23.1 5.8 11.3 3.5 1.5 47.4 47.9 6.8 1.6 18.1 53.1 23.4 25.8 0.9 6.6 15.1 10.7 1.3 3.9 16.2 7.2 26.0 4.3 38.3 60.9 16.4 ARSG KIAA1001 ENSG00000141337 "Arylsulfatase G" Q96EG1 17 68259182-68422731 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 30.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;NK-cells: 42.2;Rod photoreceptor cells: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023245, HPA023285" Enhanced "Intracellular and membrane" NA NA 4400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA023245: AB_1845056, HPA023285: AB_1845057" "unprognostic (3.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" "unprognostic (1.61e-1)" "unprognostic (9.02e-2)" "unprognostic (3.67e-3)" "unprognostic (4.11e-1)" "unprognostic (1.14e-3)" "unprognostic (5.18e-2)" "unprognostic (5.47e-2)" "unprognostic (6.11e-7)" "unprognostic (4.24e-3)" "prognostic favorable (7.04e-4)" "unprognostic (1.87e-2)" "unprognostic (3.68e-2)" "unprognostic (3.18e-2)" "unprognostic (1.49e-1)" 2.6 4.6 1.5 2.9 2.0 3.4 5.5 6.6 2.0 3.5 8.6 2.2 1.1 3.8 30.2 4.4 6.6 2.1 4.9 1.1 2.9 3.0 2.5 2.4 3.9 2.5 3.6 6.2 2.3 1.2 5.3 2.6 3.6 2.0 1.1 7.8 3.3 5.5 3.7 4.5 1.9 2.1 0.7 4.9 2.6 2.1 2.1 2.5 7.5 3.0 3.6 2.0 2.0 1.4 1.4 1.7 1.3 2.1 7.0 4.3 5.7 1.9 5.7 2.7 1.3 0.7 3.2 3.3 4.8 2.5 1.1 0.2 2.2 0.7 1.0 4.8 2.0 1.8 1.8 5.4 5.7 5.1 3.6 1.6 1.3 0.7 2.8 7.2 3.1 5.0 1.0 9.5 1.2 6.2 5.9 4.1 2.0 0.6 1.6 0.2 1.0 8.8 4.1 0.9 7.0 0.6 2.3 5.5 12.1 2.7 13.5 6.1 3.3 4.2 0.4 1.6 0.7 10.5 5.8 5.0 3.3 6.4 1.6 7.1 8.5 6.5 6.3 6.1 4.4 4.0 4.2 6.0 7.7 2.2 4.2 6.0 12.8 4.3 5.2 1.2 4.7 5.4 1.5 2.0 6.6 2.0 1.1 2.9 2.5 3.6 3.6 0.7 2.1 1.4 4.9 3.2 2.7 11.8 7.7 4.0 5.0 4.7 0.0 23.8 9.2 3.8 2.7 8.6 4.8 12.9 54.2 8.1 11.2 3.6 9.8 3.2 0.4 8.7 9.2 8.6 1.8 5.3 18.8 4.7 23.8 24.3 2.6 11.7 3.8 6.4 17.5 3.0 9.2 26.9 26.0 5.2 0.0 6.9 10.7 1.3 13.4 8.4 23.2 12.2 16.0 9.4 42.2 7.1 2.7 2.3 10.9 23.0 11.1 10.0 2.4 12.8 4.3 59.6 6.6 8.7 5.5 1.4 3.6 6.0 3.8 16.8 13.6 9.3 2.3 8.8 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 522.2;tongue: 157.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.1;Early spermatids: 26.4;Late spermatids: 29.9;Skeletal myocytes: 27.6;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "eosinophil: 50.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 50.8" "Cell line enhanced" "Detected in some" "Karpas-707: 12.8;RPMI-8226: 12.4;SK-MEL-30: 5.9;U-266/70: 42.1;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: AB_1078224" "unprognostic (5.65e-4)" "unprognostic (8.19e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.62e-6)" "unprognostic (4.11e-2)" "unprognostic (1.61e-1)" "unprognostic (5.29e-2)" "unprognostic (1.05e-3)" "unprognostic (4.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-7)" "unprognostic (2.51e-3)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.27e-1)" 2.9 0.8 0.8 5.6 2.1 0.5 1.5 0.0 1.9 12.0 0.0 66.5 4.0 31.6 0.3 4.0 26.6 0.5 78.5 0.6 0.0 0.5 0.5 3.0 7.4 0.1 0.0 2.9 0.3 0.2 0.2 0.2 0.3 14.4 0.4 0.0 6.6 0.9 522.2 2.3 18.3 1.6 0.0 4.2 17.2 0.4 0.3 0.4 1.2 157.6 3.2 30.4 8.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.4 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 12.4 0.0 0.2 0.1 0.0 0.0 0.0 5.9 0.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 42.1 8.6 1.7 0.5 2.6 0.5 0.0 0.2 50.8 1.9 2.7 0.3 1.9 1.7 3.8 4.2 0.4 0.2 0.5 0.1 0.0 7.8 0.4 2.3 1.3 0.8 2.1 0.0 1.9 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.0 0.3 3.3 0.4 0.1 8.4 0.0 0.2 0.2 0.9 51.1 0.0 2.9 0.0 0.0 0.1 3.0 0.0 0.0 1.4 26.4 1.7 0.3 0.5 0.0 2.7 4.7 0.0 0.5 1.9 1.1 2.5 0.0 0.0 0.0 0.0 0.6 0.0 1.9 0.0 0.0 0.0 0.3 29.9 0.3 5.3 1.8 1.9 5.8 0.8 2.1 0.0 0.7 0.2 0.0 0.4 10.7 0.1 0.0 0.0 0.4 1.1 0.0 27.6 5.0 0.8 8.4 0.1 0.1 2.9 14.5 0.1 0.1 0.3 ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "liver: 840.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 878.6" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.0;myeloid DC: 64.1" "Group enriched" "Detected in many" 51 "dendritic cells: 64.1;monocytes: 110.0" "Cell line enriched" "Detected in some" 9 "Hep G2: 528.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" 1.5 0.3 0.8 7.9 1.0 7.0 0.5 0.9 1.3 0.4 1.3 0.5 0.3 0.3 0.1 0.5 0.6 17.6 0.5 0.8 1.0 1.2 840.7 2.5 0.9 1.0 1.1 0.2 0.5 0.1 0.2 0.5 1.2 0.4 0.4 0.0 0.5 0.2 0.2 5.2 0.6 1.3 1.0 6.8 0.5 0.5 1.4 0.5 0.3 0.1 1.0 2.0 0.4 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 528.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.3 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.0 110.0 0.8 0.1 11.2 0.2 0.0 0.0 0.0 64.1 0.0 0.1 0.0 1.7 0.1 0.1 1.6 0.3 31.8 0.8 1.0 0.9 1.3 0.8 1.0 1.0 1.1 1.2 1.0 1.4 1.2 0.0 0.0 5.1 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 150.2 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.4 0.0 0.0 1.3 7.1 19.6 1.9 0.0 0.2 0.1 0.0 0.1 2.5 0.0 16.1 878.6 8.4 0.0 0.1 0.1 0.0 41.1 7.7 0.7 0.0 19.6 0.0 0.0 15.3 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.3 0.4 1.4 0.0 0.0 0.1 ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 386.9" "Cell type enhanced" "Detected in all" "Muller glia cells: 468.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 890.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA055161: AB_2682721, HPA059303: AB_2683973" "unprognostic (8.07e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (2.74e-2)" 386.9 160.3 64.7 50.6 69.2 16.9 106.9 102.3 88.9 65.6 84.4 78.8 45.6 49.3 44.7 71.4 46.9 61.0 111.3 64.5 58.4 59.5 74.9 74.1 20.3 54.0 69.2 62.2 44.7 38.7 36.3 47.9 52.2 48.3 84.9 219.5 101.9 70.2 357.6 35.2 45.5 67.5 44.8 28.6 105.0 16.5 71.8 16.7 97.0 182.7 28.5 112.2 43.8 60.4 460.3 652.3 89.9 55.1 392.1 370.1 31.2 804.0 741.3 336.3 350.1 113.1 594.2 35.3 54.3 474.6 270.3 167.5 56.2 281.1 570.0 13.6 57.0 81.1 372.5 310.3 251.2 12.5 12.9 306.5 61.9 187.6 237.4 657.2 144.8 18.0 22.2 32.1 300.2 97.4 3.3 16.6 51.7 441.6 383.4 22.3 97.0 7.3 206.2 374.0 93.1 32.1 249.9 116.1 101.7 49.0 47.7 22.2 456.7 338.0 174.3 313.0 288.0 20.2 27.1 1.5 890.1 7.5 231.4 1.9 8.3 0.3 2.5 2.9 4.7 5.5 3.5 2.4 10.0 5.0 4.9 2.5 25.4 8.7 1.8 34.0 4.0 4.1 64.7 69.2 102.3 88.9 64.5 58.4 54.0 69.2 52.2 44.8 71.8 60.4 79.1 195.5 244.0 366.6 13.8 47.0 160.7 126.0 68.9 138.3 83.7 58.4 228.6 37.1 157.5 86.5 294.0 118.1 40.3 57.0 15.6 144.2 1.6 51.4 65.8 85.9 116.5 13.0 93.1 180.4 107.1 132.0 73.9 115.4 8.2 34.5 42.8 62.6 72.2 127.9 98.9 215.1 52.9 26.6 44.1 3.1 70.8 48.1 42.7 61.8 20.0 468.8 2.1 154.8 53.5 257.7 32.3 57.6 15.9 148.2 34.3 34.6 66.6 158.8 46.0 114.4 92.7 3.4 16.8 101.7 50.3 48.0 13.6 131.2 67.3 254.2 ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444961-130501274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 1284.8;liver: 2037.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 398.7;Hepatocytes: 1062.0;Proximal enterocytes: 618.2;Proximal tubular cells: 1408.9;Urothelial cells: 413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "BJ hTERT+: 893.9;HaCaT: 850.4;hTCEpi: 817.8;RPMI-8226: 1444.5;THP-1: 1061.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020896, HPA020934" Enhanced Supported Nucleoplasm,Cytosol No No 6400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA020896: AB_1845117, HPA020934: AB_1845118" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (8.14e-9)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.92e-3)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (3.14e-1)" "unprognostic (4.72e-3)" 215.0 146.8 29.6 51.3 29.7 0.2 168.2 25.0 31.0 67.0 61.7 157.2 124.5 111.3 124.8 51.1 166.3 110.2 66.5 31.5 38.3 1284.8 2037.7 52.9 7.5 40.2 42.2 57.2 68.4 11.4 45.0 50.6 51.7 56.2 167.9 6.9 119.4 132.6 74.4 131.3 194.8 61.2 28.4 20.0 53.2 35.9 38.4 7.8 92.3 71.4 15.6 288.7 66.6 25.3 124.5 11.9 13.7 23.1 88.4 223.1 43.6 146.2 893.9 28.2 85.5 52.5 34.0 0.4 95.9 300.2 8.2 850.4 59.9 5.2 19.5 21.7 27.1 0.3 18.3 137.3 305.4 18.3 1.6 148.2 817.8 45.4 81.2 0.3 1.1 384.0 5.3 530.6 28.8 619.8 7.2 262.7 19.2 635.9 26.7 1.7 15.4 1444.5 78.8 61.3 342.4 5.8 515.4 534.7 41.5 53.5 366.1 1061.5 0.4 11.3 68.3 2.3 13.0 88.1 91.5 32.1 219.0 137.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 29.6 29.7 25.0 31.0 31.5 38.3 40.2 42.2 51.7 28.4 38.4 25.3 72.1 25.6 28.6 2.6 21.3 70.5 55.7 179.8 53.5 0.1 23.7 17.3 5.4 138.7 104.4 47.8 0.0 178.5 0.4 398.7 133.1 116.5 1.2 4.7 30.5 68.0 12.0 93.7 2.2 110.5 8.9 21.5 20.4 6.2 5.7 55.5 65.7 1062.0 14.7 0.0 8.0 186.8 24.4 40.1 6.5 7.8 31.1 8.0 3.6 7.5 1.6 10.6 0.0 0.0 0.2 70.8 310.4 124.8 11.7 104.0 618.2 1408.9 32.7 0.4 0.0 18.7 13.4 1.4 2.6 23.5 17.5 144.1 11.5 62.0 165.6 413.2 ATAD1 "FLJ14600, Msp1" ENSG00000138138 "ATPase family AAA domain containing 1" Q8NBU5 10 87751512-87841361 "Disease related genes, Human disease related genes, Predicted membrane proteins" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 16 "Early spermatids: 987.5;Late spermatids: 1846.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved "Nucleoli rim,Mitochondria" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Nucleoli rim" Mitochondria "HPA037569: AB_10672496" "unprognostic (9.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (3.24e-2)" "unprognostic (6.60e-3)" "unprognostic (3.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (8.45e-2)" "unprognostic (1.35e-3)" "unprognostic (1.67e-2)" "prognostic favorable (3.98e-6)" "unprognostic (2.35e-1)" "unprognostic (3.29e-1)" "unprognostic (3.45e-2)" "unprognostic (4.22e-2)" 15.7 17.4 9.9 9.0 10.3 4.9 16.3 11.3 12.6 16.0 10.7 18.2 10.9 16.8 13.7 16.2 13.8 10.5 36.1 10.4 11.5 16.7 18.0 14.5 11.8 10.7 11.5 15.9 12.7 28.5 13.4 15.2 11.1 18.7 14.5 28.0 14.9 16.1 37.2 15.1 12.5 13.6 10.0 10.0 13.6 26.4 11.0 13.8 17.4 31.8 12.1 15.5 16.0 10.2 18.8 18.2 20.8 18.2 27.4 29.5 14.4 19.7 33.4 19.6 20.6 14.6 53.8 17.6 15.4 17.3 9.8 31.3 18.9 14.4 21.2 18.6 26.4 15.3 24.0 18.8 30.5 41.7 8.0 23.0 45.4 20.7 42.1 37.2 12.7 14.1 15.9 20.7 22.7 11.2 23.1 22.9 16.4 13.9 10.0 15.8 13.2 19.2 28.9 13.4 14.2 31.5 20.3 12.3 32.0 21.0 29.1 18.0 19.3 16.2 13.9 11.2 24.5 25.4 39.4 22.5 20.8 23.7 11.5 8.4 2.8 4.9 6.3 4.9 10.3 7.2 7.3 8.3 5.4 5.7 9.1 8.6 1.7 8.6 6.9 4.6 7.6 5.7 9.9 10.3 11.3 12.6 10.4 11.5 10.7 11.5 11.1 10.0 11.0 10.2 31.0 54.5 28.0 46.4 41.4 26.8 42.9 46.2 44.3 50.4 29.8 20.8 81.3 27.1 44.9 22.0 35.5 37.7 35.2 33.8 23.5 37.0 987.5 22.3 38.3 21.7 22.8 24.6 69.0 28.0 33.2 35.6 32.6 28.7 29.2 23.1 20.0 28.9 27.3 70.7 73.1 22.9 50.8 18.0 20.1 1846.8 35.8 25.1 32.0 37.5 16.1 59.6 23.7 58.8 52.7 39.0 25.2 47.0 32.3 42.3 20.5 29.5 44.8 54.8 59.2 29.5 43.8 77.2 29.8 34.6 30.1 88.4 40.0 34.8 23.7 54.6 ATG2A KIAA0404 ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" 16.4 20.1 11.4 6.5 10.9 60.2 16.9 8.6 40.1 19.9 11.4 18.9 7.5 18.2 1.8 15.7 19.2 4.2 18.4 11.5 9.8 22.0 59.2 24.2 6.1 13.9 12.3 24.9 22.7 4.9 21.6 4.9 12.7 21.6 2.6 1.9 15.2 5.7 26.7 34.9 21.4 3.3 9.0 25.7 23.2 15.3 11.4 5.4 19.3 4.4 3.3 17.7 15.6 10.4 13.2 12.6 4.4 12.0 5.7 4.0 12.3 7.1 10.3 9.4 6.8 11.0 9.9 9.3 14.7 6.0 12.0 10.8 4.5 8.3 2.5 9.1 15.7 8.7 19.1 10.0 8.4 6.5 18.2 10.9 7.1 11.8 6.3 5.4 7.9 9.5 16.1 7.3 4.1 21.3 7.8 21.9 5.1 3.5 14.3 8.6 7.1 13.5 5.0 10.9 16.5 6.7 10.6 14.6 13.3 3.3 14.3 8.1 10.1 9.0 8.6 18.3 5.3 14.7 5.5 6.5 13.0 5.2 5.6 3.0 2.0 2.2 2.5 2.1 2.1 0.8 1.7 2.2 1.4 0.9 1.3 2.4 16.9 1.8 1.7 2.4 0.9 1.2 11.4 10.9 8.6 40.1 11.5 9.8 13.9 12.3 12.7 9.0 11.4 10.4 9.8 9.6 16.2 20.2 17.0 28.9 8.7 35.7 16.5 16.6 15.8 10.3 8.1 7.2 17.6 9.2 33.3 12.7 40.1 38.8 1.9 10.2 2.5 12.4 9.2 10.2 35.9 16.2 7.6 10.3 5.3 12.6 16.8 24.4 9.5 15.4 7.9 23.2 10.9 13.5 8.4 17.6 24.4 20.1 19.9 3.6 12.8 24.2 30.2 5.6 11.9 12.3 19.6 6.6 7.1 14.9 21.7 10.1 27.3 12.2 26.8 6.6 13.3 26.0 13.1 11.6 10.6 9.0 6.2 16.3 38.4 66.9 40.2 27.2 19.0 15.9 ATOH8 "bHLHa21, FLJ14708, HATH6" ENSG00000168874 "Atonal bHLH transcription factor 8" Q96SQ7 2 85751344-85791383 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.7" "Cell type enhanced" "Detected in many" "Adipocytes: 123.8;Endothelial cells: 41.7;Hepatocytes: 39.1;Muller glia cells: 32.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.2;fHDF/TERT166: 6.8;hTERT-RPE1: 5.0;RH-30: 9.5;RT4: 5.6;TIME: 7.9;U-2197: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028406 Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA028406: AB_2672587" "unprognostic (7.70e-2)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (2.84e-3)" "unprognostic (2.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.78e-1)" "unprognostic (6.28e-3)" "unprognostic (1.56e-1)" "prognostic favorable (8.98e-6)" "unprognostic (3.32e-2)" "prognostic favorable (3.80e-5)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-2)" 33.8 1.8 2.1 0.3 2.2 0.0 29.9 2.7 1.6 20.9 0.5 8.8 0.2 25.9 0.2 5.6 19.4 0.4 30.6 1.5 5.1 7.3 25.1 25.6 0.8 5.7 4.9 15.0 4.2 0.2 5.4 0.3 5.3 17.4 0.4 0.6 5.2 1.9 54.7 19.9 8.9 1.3 1.6 12.2 9.4 2.1 3.1 0.2 48.5 2.0 0.1 21.7 20.6 3.3 0.0 1.1 4.1 6.2 3.0 0.4 0.0 3.4 0.5 0.8 0.3 0.0 0.0 0.0 1.1 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.1 1.6 0.0 0.0 2.1 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 9.5 0.0 0.0 5.6 3.0 1.4 0.6 0.0 0.6 0.0 0.0 0.0 7.9 1.2 0.0 5.5 0.0 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.7 1.6 1.5 5.1 5.7 4.9 5.3 1.6 3.1 3.3 123.8 9.6 18.3 10.7 0.3 2.5 8.5 11.8 0.6 0.4 0.5 0.8 13.2 5.7 17.5 1.8 0.0 0.1 0.1 1.1 0.0 11.9 13.6 5.9 5.7 41.7 4.2 0.0 0.3 2.3 0.6 11.4 1.1 20.5 1.3 5.3 5.7 39.1 3.2 0.0 0.3 2.2 6.1 3.1 4.0 25.9 3.4 4.3 1.8 5.6 0.6 32.3 0.0 14.6 3.1 1.0 5.5 0.4 0.0 4.5 0.0 0.6 2.4 1.3 0.0 12.2 11.6 3.0 2.7 0.2 1.4 0.3 0.5 0.1 1.0 2.3 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.1;gallbladder: 16.6;intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 136.4;Oligodendrocyte precursor cells: 293.0;Oligodendrocytes: 419.4;Undifferentiated cells: 90.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 13.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034574 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.1 0.0 4.1 5.0 9.0 0.0 0.4 8.8 6.4 1.0 0.1 44.5 24.7 0.0 12.3 6.2 0.4 16.6 0.0 4.3 5.0 0.1 0.0 0.0 0.0 10.6 7.8 0.0 2.9 0.0 0.0 0.0 9.9 0.0 45.7 0.0 1.8 0.7 0.0 7.1 21.0 1.5 5.8 0.0 4.8 0.3 8.0 5.0 0.0 0.0 2.9 1.5 2.5 17.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 9.0 8.8 6.4 4.3 5.0 10.6 7.8 9.9 5.8 8.0 17.1 0.1 0.0 0.0 42.7 0.6 0.4 0.1 12.9 0.0 0.0 0.1 0.0 1.2 21.5 15.1 1.8 0.0 0.0 0.0 136.4 0.0 23.6 0.2 0.2 0.0 0.3 13.2 0.0 4.0 20.3 0.1 0.0 10.7 0.3 0.0 0.0 0.0 0.3 0.1 0.0 3.9 55.4 4.1 0.0 1.2 0.6 0.0 0.1 1.8 1.9 1.6 0.0 0.0 293.0 419.4 16.4 64.7 0.0 0.4 0.1 24.1 0.0 16.0 0.0 0.0 0.0 0.6 0.0 0.1 2.9 0.9 0.5 0.3 0.0 90.7 6.5 ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 515.9;skeletal muscle: 882.2;tongue: 478.0" "Cell type enhanced" "Detected in some" "Astrocytes: 515.8;Cardiomyocytes: 158.7;Microglial cells: 141.5;Muller glia cells: 73.0;Oligodendrocyte precursor cells: 94.0;Sertoli cells: 85.5" "Cancer enriched" "Detected in many" 18 "glioma: 91.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 51.9;HHSteC: 14.6;RH-30: 16.8;U-87 MG: 10.3" "Low region specificity" "Detected in all" CAB022230 Enhanced NA NA 170000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022230: " "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.16e-2)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.85e-2)" "unprognostic (8.63e-4)" "unprognostic (1.70e-2)" "unprognostic (9.40e-3)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (5.32e-3)" 37.4 4.1 401.5 1.5 480.5 0.0 27.4 419.8 412.8 9.3 164.9 55.8 3.6 5.6 12.5 33.5 14.5 8.0 144.6 337.4 398.5 3.9 1.2 6.4 0.3 429.5 478.8 18.9 1.4 0.3 32.3 3.3 375.3 28.5 8.1 58.5 18.2 28.5 882.2 4.7 15.9 7.8 365.0 1.8 15.7 5.8 515.9 0.6 3.5 478.0 0.5 29.9 9.8 327.7 0.0 0.0 51.9 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 4.6 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 401.5 480.5 419.8 412.8 337.4 398.5 429.5 478.8 375.3 365.0 515.9 327.7 1.4 0.0 0.0 515.8 0.1 0.5 1.6 0.0 0.6 1.3 2.5 0.9 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 1.2 11.1 0.0 0.0 5.5 0.0 0.0 4.8 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 1.3 1.4 28.9 0.5 0.0 141.5 0.5 73.0 0.0 94.0 2.5 0.0 0.0 39.5 0.0 0.8 0.0 0.1 0.1 3.9 85.5 54.9 45.8 0.3 0.2 0.2 0.6 0.1 0.1 5.8 0.0 0.6 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.4;skin 1: 26.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 56.2;Club cells: 50.0;Intestinal goblet cells: 82.3;Oligodendrocyte precursor cells: 58.8;Respiratory ciliated cells: 78.2;Undifferentiated cells: 77.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 24.5;OE19: 44.4;RT4: 19.3;SK-BR-3: 33.0;T-47d: 11.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA052262: AB_2681776, HPA075812: AB_2686765" "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favorable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.0 0.0 1.4 2.4 1.4 11.0 2.5 0.5 1.3 6.4 0.5 30.1 27.3 1.0 0.1 4.7 6.8 4.6 0.0 1.3 1.1 1.8 0.1 10.5 0.0 1.0 0.9 0.0 0.7 3.3 1.0 0.9 1.0 12.5 37.4 0.9 19.6 0.2 0.1 26.0 20.3 0.6 0.6 0.4 5.9 0.4 1.1 0.0 8.9 0.0 0.5 4.0 4.6 0.8 6.2 0.4 0.9 0.1 0.0 0.0 6.4 0.2 0.0 0.0 0.0 5.8 5.2 0.0 0.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.5 0.0 0.0 0.0 44.4 0.1 0.0 0.0 0.2 0.0 19.3 4.9 0.0 0.0 33.0 0.2 0.9 11.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 1.4 0.5 1.3 1.3 1.1 1.0 0.9 1.0 0.6 1.1 0.8 0.0 32.1 56.2 4.2 0.0 0.6 14.3 39.9 0.6 1.3 20.8 3.2 0.8 5.7 50.0 0.0 0.0 2.0 0.1 44.4 0.0 9.0 3.2 26.8 2.5 0.7 34.2 0.0 8.3 2.5 2.4 0.5 22.4 28.0 8.9 0.0 0.0 0.1 0.3 0.0 1.8 82.3 8.2 0.0 1.2 1.9 0.0 0.6 1.8 1.0 0.0 1.9 0.0 58.8 2.4 4.7 29.2 0.0 0.0 13.8 10.2 1.8 78.2 5.2 0.0 0.1 1.8 0.8 1.0 1.5 1.1 24.1 0.9 0.2 77.1 9.9 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2590.4;tongue: 3205.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 821.1;Distal tubular cells: 1238.5;Extravillous trophoblasts: 592.7;Hofbauer cells: 608.9;Proximal tubular cells: 951.7;Syncytiotrophoblasts: 1138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 19000000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavorable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favorable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 432.7 555.5 217.6 300.5 231.4 465.8 301.5 281.6 303.8 241.8 443.3 741.6 689.5 235.4 223.4 527.6 277.9 225.7 2011.6 233.0 307.1 945.9 609.3 253.4 294.6 264.2 242.9 200.2 301.7 1311.6 252.6 301.4 280.4 280.9 767.6 484.2 407.7 356.4 2590.4 398.6 575.5 332.5 230.9 272.5 494.9 236.0 277.5 390.9 342.8 3205.3 458.3 404.1 311.2 244.7 693.6 834.9 632.3 1003.6 578.3 596.7 1159.8 683.2 645.6 1179.1 663.9 1375.7 755.6 1236.3 723.0 863.5 482.9 906.1 1378.1 851.5 1039.4 579.9 987.5 1333.1 726.4 872.5 716.6 1509.7 912.9 755.1 843.3 918.0 1171.2 870.2 985.8 901.7 1246.3 1363.1 992.2 671.5 1134.4 941.3 1085.9 905.6 1637.6 1079.3 711.0 1603.5 1315.6 1196.7 737.5 658.2 1042.3 1481.3 1214.0 663.4 1404.1 1151.8 657.6 454.8 507.9 671.9 751.0 659.5 865.7 1254.8 684.7 1007.8 718.4 403.5 549.4 281.8 293.5 643.6 326.3 303.2 275.4 313.6 713.4 248.4 221.0 266.8 137.1 296.9 750.6 360.9 372.9 1077.1 217.6 231.4 281.6 303.8 233.0 307.1 264.2 242.9 280.4 230.9 277.5 244.7 172.3 134.6 173.2 0.0 48.6 0.0 0.0 0.0 0.0 0.0 176.8 149.1 0.0 0.0 81.1 277.7 0.0 821.1 141.5 0.0 1238.5 517.7 0.0 194.1 169.2 115.7 0.0 0.0 0.0 367.9 592.7 115.0 0.0 163.3 145.1 267.6 0.0 0.0 608.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.3 0.0 0.0 281.2 0.0 0.0 0.0 0.0 333.3 0.0 0.0 26.8 0.0 0.0 951.7 102.7 0.0 0.0 0.0 151.1 0.0 0.0 0.0 0.0 1138.6 77.4 518.4 0.0 0.0 ATP5F1E ATP5E ENSG00000124172 "ATP synthase F1 subunit epsilon" P56381 20 59025475-59032345 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 3414.2;Hofbauer cells: 2765.4;Proximal tubular cells: 4125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.73e-1)" "unprognostic (6.30e-2)" "unprognostic (8.16e-2)" "unprognostic (9.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.92e-3)" "unprognostic (7.88e-3)" "unprognostic (2.51e-1)" "unprognostic (5.01e-2)" "unprognostic (6.41e-2)" "unprognostic (4.35e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (3.98e-1)" "unprognostic (3.21e-1)" "unprognostic (1.67e-1)" "unprognostic (2.44e-2)" 81.4 88.3 92.2 98.5 94.5 125.6 62.3 95.3 135.8 49.3 95.7 77.2 80.1 51.2 25.3 77.0 45.2 13.9 162.8 92.7 95.7 128.5 80.2 69.3 69.8 94.2 94.0 42.1 44.9 52.9 104.8 34.0 94.4 50.6 33.1 42.8 62.7 23.7 240.1 42.8 78.9 25.6 95.4 93.5 69.5 47.7 93.7 64.7 64.1 107.0 40.0 63.4 55.5 97.1 150.0 49.6 98.1 90.0 94.0 87.2 65.2 155.9 60.6 102.2 66.0 156.3 143.5 81.1 184.7 82.7 159.6 141.5 70.3 123.7 67.0 66.7 76.4 271.4 107.2 136.5 86.4 193.2 234.6 95.0 105.3 62.5 77.8 99.8 76.9 107.6 103.6 113.8 59.4 144.4 247.8 299.1 32.9 220.4 203.4 120.2 138.3 156.8 107.5 83.0 98.0 146.6 261.6 273.9 328.4 83.5 182.5 312.8 264.3 208.3 222.0 138.9 213.7 180.2 245.9 238.1 201.5 117.9 117.1 613.1 420.6 757.3 237.5 463.8 224.9 351.4 285.8 268.7 356.0 291.7 227.8 259.4 713.9 243.1 470.7 601.7 393.3 781.7 92.2 94.5 95.3 135.8 92.7 95.7 94.2 94.0 94.4 95.4 93.7 97.1 1036.3 516.0 530.8 0.0 331.5 0.0 0.0 0.0 0.0 0.0 1042.4 1138.3 0.0 0.0 289.7 1121.9 0.0 705.8 812.6 0.0 3414.2 998.0 0.0 1145.2 1007.1 436.6 0.0 0.0 0.0 1202.6 956.9 341.7 0.0 1410.3 352.0 594.0 0.0 0.0 2765.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.4 0.0 0.0 1473.1 0.0 0.0 0.0 0.0 1427.7 0.0 0.0 132.5 0.0 0.0 4125.3 392.8 0.0 0.0 0.0 334.0 0.0 0.0 0.0 0.0 590.5 431.2 731.9 0.0 0.0 ATP5MC3 ATP5G3 ENSG00000154518 "ATP synthase membrane subunit c locus 3" P48201 2 175176258-175181710 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1214.0;tongue: 1088.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 880.5;Distal tubular cells: 2666.7;Extravillous trophoblasts: 1022.6;Hofbauer cells: 1008.2;Proximal tubular cells: 2131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (4.45e-3)" "unprognostic (1.67e-1)" "prognostic favorable (9.90e-4)" "unprognostic (1.67e-3)" "unprognostic (3.01e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.46e-2)" "unprognostic (6.03e-3)" "unprognostic (1.42e-2)" "unprognostic (7.90e-2)" "unprognostic (4.71e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.31e-6)" "unprognostic (2.86e-1)" "unprognostic (3.93e-1)" "unprognostic (4.55e-2)" "unprognostic (2.31e-2)" 195.7 199.2 134.9 131.1 142.0 141.2 164.5 160.3 155.0 126.4 168.1 343.9 378.7 127.8 126.5 305.3 107.3 75.8 1214.0 143.0 164.7 432.4 385.3 118.1 127.3 153.7 143.6 99.7 120.2 550.6 139.5 102.4 157.3 110.0 315.0 126.5 184.8 114.5 777.9 169.7 297.3 122.2 147.4 131.4 272.4 62.3 154.2 188.9 135.1 1088.5 176.3 171.8 165.4 150.0 268.4 232.3 346.7 381.8 290.0 255.9 387.1 242.7 255.1 334.8 290.9 700.0 216.4 661.1 276.5 272.0 365.7 343.3 440.2 419.9 348.5 278.3 411.7 538.7 312.1 896.6 225.9 702.4 308.8 279.9 317.7 377.5 239.3 257.4 341.9 313.2 587.0 305.1 370.3 361.9 541.1 587.3 460.6 638.4 726.1 417.1 321.5 648.4 664.5 590.9 310.5 196.3 195.1 521.4 557.0 487.5 313.4 567.0 231.6 55.9 263.2 1.7 338.0 239.5 327.1 582.4 319.8 420.8 251.8 115.2 293.9 126.9 168.4 332.1 170.7 202.4 176.5 184.2 425.2 163.2 164.2 181.1 32.6 197.9 309.4 314.5 204.0 438.5 134.9 142.0 160.3 155.0 143.0 164.7 153.7 143.6 157.3 147.4 154.2 150.0 250.4 176.3 157.2 0.0 69.0 0.0 0.0 0.0 0.0 0.0 324.8 399.4 0.0 0.0 125.7 310.8 0.0 880.5 134.2 0.0 2666.7 479.0 0.0 271.2 264.1 79.3 0.0 0.0 0.0 375.2 1022.6 154.1 0.0 301.5 88.3 236.8 0.0 0.0 1008.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 205.5 0.0 0.0 205.7 0.0 0.0 0.0 0.0 391.9 0.0 0.0 26.5 0.0 0.0 2131.8 129.7 0.0 0.0 0.0 181.9 0.0 0.0 0.0 0.0 690.9 81.0 469.5 0.0 0.0 ATP5MD "bA792D24.4, DAPIT, MGC14697, USMG5" ENSG00000173915 "ATP synthase membrane subunit DAPIT" Q96IX5 10 103389041-103396492 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1340.2;Ductal cells: 705.9;Exocrine glandular cells: 723.1;Pancreatic endocrine cells: 884.5;Proximal tubular cells: 1879.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044798 Supported Mitochondria NA NA 55000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA044798: AB_2679091" "unprognostic (4.41e-2)" "unprognostic (3.08e-2)" "unprognostic (2.59e-1)" "unprognostic (7.93e-2)" "unprognostic (1.65e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (1.57e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (7.46e-2)" "unprognostic (1.03e-2)" 332.3 343.0 502.9 155.1 517.7 193.0 324.6 514.9 721.8 215.1 515.2 484.6 273.5 176.9 410.2 426.1 194.3 140.8 1229.7 526.1 539.0 546.7 587.1 215.3 180.3 501.2 501.9 157.5 321.4 519.2 309.2 157.4 506.1 254.2 449.6 245.3 234.8 236.4 1019.3 204.6 261.7 229.8 511.8 185.4 369.8 142.5 509.3 319.0 191.2 1325.5 251.0 284.7 258.9 518.0 557.8 559.4 528.4 648.2 570.2 696.0 348.3 523.2 612.7 501.0 556.6 925.2 605.3 312.4 288.9 575.3 398.6 559.4 502.2 522.7 697.9 414.7 887.3 331.8 682.1 1057.7 545.7 688.3 491.3 569.2 801.1 456.4 715.7 849.2 661.5 470.0 441.5 517.5 849.4 842.0 552.0 1167.5 397.8 830.1 959.1 355.8 326.0 495.3 1218.4 878.4 203.7 464.8 269.4 419.7 824.9 723.5 373.4 619.9 388.6 255.2 394.2 394.0 692.8 537.2 958.4 543.5 545.2 678.2 200.3 575.3 271.2 395.8 214.7 384.0 248.0 301.6 296.3 259.8 314.1 219.1 251.4 256.7 231.1 230.5 375.3 456.3 307.9 304.4 502.9 517.7 514.9 721.8 526.1 539.0 501.2 501.9 506.1 511.8 509.3 518.0 169.1 211.5 173.2 0.0 40.9 0.0 0.0 0.0 0.0 0.0 323.4 417.6 0.0 0.0 91.0 388.1 0.0 298.0 76.3 0.0 1340.2 705.9 0.0 406.0 245.4 114.5 0.0 0.0 0.0 723.1 439.4 81.8 0.0 424.5 118.6 176.9 0.0 0.0 543.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.4 0.0 0.0 432.6 0.0 0.0 0.0 0.0 884.5 0.0 0.0 0.0 0.0 0.0 1879.7 121.0 0.0 0.0 0.0 127.9 0.0 0.0 0.0 0.0 305.8 69.4 209.9 0.0 0.0 ATP5PD "ATP5H, ATP5JD, ATPQ" ENSG00000167863 "ATP synthase peripheral stalk subunit d" O75947 17 75038863-75046985 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1142.6;Hofbauer cells: 465.0;Proximal tubular cells: 1059.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042777, HPA048459" Enhanced Supported Mitochondria NA NA 60000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042777: AB_2678160, HPA048459: AB_2680402" "unprognostic (1.37e-1)" "unprognostic (4.41e-2)" "unprognostic (1.70e-3)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "unprognostic (4.81e-2)" "unprognostic (7.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (2.72e-1)" "unprognostic (8.72e-2)" "unprognostic (2.56e-2)" "unprognostic (1.42e-1)" "unprognostic (3.26e-1)" "unprognostic (1.73e-1)" "unprognostic (4.29e-2)" 253.8 271.0 253.5 156.0 260.5 187.2 228.8 270.5 385.7 190.7 282.9 337.1 295.1 170.7 279.9 355.9 173.5 140.1 985.5 261.9 271.1 465.2 454.2 174.0 166.0 264.8 256.9 147.5 222.2 427.1 203.9 174.1 260.8 177.9 323.6 256.0 240.8 200.5 1102.8 264.7 257.4 211.3 260.2 155.0 307.4 93.8 262.3 175.2 263.7 1025.5 221.2 230.3 221.5 261.7 522.8 445.4 335.6 439.8 532.6 647.4 449.1 437.2 571.3 478.5 452.2 351.8 397.1 349.8 282.5 550.2 450.2 462.2 409.0 571.6 637.5 171.6 346.0 359.1 340.2 703.1 524.2 463.5 225.8 555.3 444.8 390.7 552.7 380.9 646.8 268.5 380.1 462.6 595.1 503.3 461.8 515.6 257.1 1185.3 626.9 322.3 970.4 652.3 1007.3 499.7 335.8 368.5 515.5 811.0 730.7 496.9 805.1 463.2 337.4 591.1 413.2 520.0 520.4 369.0 315.5 360.8 530.2 455.4 390.3 410.8 440.7 481.0 274.8 540.9 320.8 364.5 467.5 341.7 509.7 292.8 416.1 388.9 253.0 301.6 458.0 453.6 492.8 495.9 253.5 260.5 270.5 385.7 261.9 271.1 264.8 256.9 260.8 260.2 262.3 261.7 173.8 173.1 156.4 0.0 35.0 0.0 0.0 0.0 0.0 0.0 159.6 234.2 0.0 0.0 102.8 259.3 0.0 384.3 74.0 0.0 1142.6 313.6 0.0 188.2 153.6 70.4 0.0 0.0 0.0 379.5 328.4 82.7 0.0 207.6 88.3 84.6 0.0 0.0 465.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.1 0.0 0.0 208.8 0.0 0.0 0.0 0.0 284.3 0.0 0.0 13.8 0.0 0.0 1059.2 101.3 0.0 0.0 0.0 88.3 0.0 0.0 0.0 0.0 336.3 54.4 155.9 0.0 0.0 ATP5PF "ATP5, ATP5A, ATP5J, ATPM, CF6" ENSG00000154723 "ATP synthase peripheral stalk subunit F6" P18859 21 25716503-25735673 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1595.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 2375.2;Proximal tubular cells: 1906.2;Syncytiotrophoblasts: 708.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031069 Supported Supported Mitochondria NA NA 820000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA031069: AB_10603676" "unprognostic (3.52e-2)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (7.87e-2)" "unprognostic (1.43e-1)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (4.87e-2)" "unprognostic (1.77e-1)" "unprognostic (8.83e-2)" "prognostic favorable (2.37e-5)" "unprognostic (1.93e-1)" "unprognostic (9.20e-2)" "unprognostic (1.56e-1)" "unprognostic (2.15e-2)" 274.6 276.3 291.2 136.4 295.4 175.1 205.5 302.5 424.4 156.3 316.1 333.5 276.4 128.8 368.1 258.1 129.9 129.7 1052.1 295.2 306.2 489.5 756.3 110.8 166.4 299.3 297.8 127.2 188.2 458.8 140.4 171.5 295.7 160.1 314.4 249.5 214.6 228.5 1161.7 113.6 250.6 189.8 298.7 111.2 226.9 131.5 299.4 217.5 166.0 1595.8 210.9 194.9 138.4 299.6 355.9 260.0 314.5 351.4 344.8 313.5 389.4 305.8 373.0 305.8 300.8 607.6 274.4 439.3 194.2 312.9 467.8 191.5 441.3 379.2 339.2 373.1 441.1 910.6 520.6 618.4 386.8 673.2 284.5 303.1 471.2 284.0 258.6 399.9 363.0 412.2 582.2 522.9 458.2 416.3 468.6 683.2 562.3 824.0 460.7 358.0 606.5 840.0 669.8 504.6 360.2 394.1 516.5 521.7 493.0 449.4 376.5 590.5 260.6 219.6 266.6 209.3 265.9 501.7 954.7 568.2 341.5 707.8 283.1 444.8 447.0 443.7 293.3 487.1 316.1 475.1 385.5 368.6 531.9 399.7 377.4 370.7 292.3 389.9 505.7 504.0 520.3 661.3 291.2 295.4 302.5 424.4 295.2 306.2 299.3 297.8 295.7 298.7 299.4 299.6 532.1 169.9 179.3 0.0 56.0 0.0 0.0 0.0 0.0 0.0 346.3 468.4 0.0 0.0 105.9 419.3 0.0 652.7 116.4 0.0 2375.2 447.0 0.0 299.2 257.6 150.6 0.0 0.0 0.0 472.5 522.8 135.6 0.0 308.5 109.7 341.2 0.0 0.0 522.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 154.2 0.0 0.0 226.4 0.0 0.0 0.0 0.0 427.1 0.0 0.0 21.4 0.0 0.0 1906.2 142.1 0.0 0.0 0.0 161.4 0.0 0.0 0.0 0.0 708.2 79.2 387.8 0.0 0.0 ATP6AP2 "APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR" ENSG00000182220 "ATPase H+ transporting accessory protein 2" O75787 X 40579372-40606848 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Congenital disorder of glycosylation, Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 765.1" "Cell type enhanced" "Detected in all" "Hofbauer cells: 702.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003156 Approved NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA003156: AB_1078245" "unprognostic (1.45e-1)" "unprognostic (3.80e-3)" "unprognostic (1.30e-1)" "unprognostic (7.19e-2)" "unprognostic (8.58e-3)" "unprognostic (1.29e-1)" "unprognostic (1.63e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-1)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.01e-5)" "unprognostic (2.34e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-2)" "unprognostic (2.86e-2)" 81.2 71.5 85.6 60.6 86.5 124.4 95.1 76.4 116.9 106.1 72.4 82.9 32.1 86.6 91.3 70.1 75.6 79.7 55.1 90.8 90.2 165.6 96.8 87.3 67.4 80.4 79.8 68.9 53.3 765.1 30.7 106.9 83.4 86.6 89.0 99.3 39.4 97.9 18.4 71.9 47.8 124.7 84.6 69.0 49.1 40.4 87.6 72.0 177.1 40.1 72.5 97.7 41.4 98.7 83.9 117.5 78.7 106.7 472.6 312.4 47.9 182.4 274.1 127.0 152.9 68.0 142.6 48.4 88.1 257.0 141.3 86.6 114.0 136.0 168.2 92.7 97.7 57.5 100.2 66.5 172.0 104.6 111.6 259.6 175.2 154.2 121.4 200.3 168.1 46.1 63.8 130.7 201.7 109.8 45.5 93.7 73.4 140.8 112.7 43.8 132.6 161.6 182.8 96.8 55.2 51.9 185.8 111.7 118.4 284.2 147.8 97.1 172.5 175.0 91.3 207.7 62.8 38.0 70.7 46.2 139.1 93.0 138.5 269.0 511.1 404.8 156.1 364.9 164.3 106.7 157.3 161.9 341.3 110.3 174.8 159.3 255.9 141.2 378.6 124.2 167.2 692.9 85.6 86.5 76.4 116.9 90.8 90.2 80.4 79.8 83.4 84.6 87.6 98.7 102.3 57.7 65.6 36.2 65.4 97.3 135.4 254.3 46.1 155.8 74.1 61.2 30.4 94.4 175.4 138.0 54.2 173.4 109.6 70.3 62.6 146.6 3.6 97.2 115.5 94.7 57.1 62.3 44.8 59.1 106.3 156.5 34.7 124.5 87.5 63.7 96.0 64.0 702.2 188.4 56.3 54.6 349.9 279.5 263.3 9.5 117.4 222.0 149.4 28.1 185.4 193.0 72.1 40.2 40.6 64.0 58.9 151.2 74.8 97.9 61.0 106.4 127.4 93.3 105.2 116.7 138.7 106.7 43.1 60.0 99.9 174.4 100.3 188.2 63.6 121.1 ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 63.6;salivary gland: 78.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 16.5;Cytotrophoblasts: 13.4;Distal tubular cells: 31.3;Ionocytes: 57.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SK-BR-3: 55.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favorable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" 0.2 0.0 0.3 0.0 0.4 0.0 4.7 0.1 0.5 3.7 3.1 0.0 0.1 0.1 1.2 4.9 0.0 0.0 0.0 0.6 0.2 63.6 0.0 0.4 0.0 0.3 0.2 0.0 0.1 1.6 0.1 2.5 0.2 0.9 0.0 0.0 78.4 1.5 0.0 10.2 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.4 0.0 0.0 3.7 0.1 0.2 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.6 0.6 1.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 5.0 1.9 0.0 0.1 0.0 0.1 0.1 0.6 0.0 4.5 0.2 0.0 0.0 0.1 55.7 1.9 2.9 0.1 0.0 0.2 0.6 1.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.5 0.6 0.2 0.3 0.2 0.2 0.2 0.3 0.3 0.0 0.0 1.1 0.3 0.0 0.0 1.1 0.9 0.0 0.0 2.5 1.4 0.5 0.0 1.7 16.5 2.1 13.4 0.3 0.0 31.3 0.0 2.2 0.9 0.1 0.1 0.0 0.0 1.4 0.0 0.7 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 57.0 0.0 0.0 2.8 0.3 0.0 7.2 1.0 0.0 0.0 0.0 6.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 4.4 0.1 0.0 0.0 0.1 0.6 0.7 0.0 0.1 5.1 0.2 0.0 0.0 1.3 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325525-154351304 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.8;Excitatory neurons: 28.5;Inhibitory neurons: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;T-cells: 3.7" "Cell line enhanced" "Detected in many" "ASC diff: 120.9;fHDF/TERT166: 112.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046680, HPA061103" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" "Nucleoli, Cytosol" "HPA046680: AB_2679749, HPA061103: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (5.29e-5)" 17.2 9.5 8.2 22.7 7.8 5.4 14.0 18.8 11.0 28.7 20.7 17.8 12.5 39.2 17.7 11.0 30.8 18.2 15.2 10.8 9.2 6.3 3.4 18.0 25.4 8.9 8.1 35.3 5.9 10.5 19.3 15.3 9.6 18.9 9.1 2.1 7.2 21.2 3.5 8.5 17.6 39.7 5.6 19.5 14.5 16.3 8.8 18.4 15.0 7.4 19.6 19.7 17.9 7.7 2.1 15.6 20.0 20.5 120.9 80.4 0.3 41.8 77.4 26.1 30.5 0.3 0.6 1.9 21.4 112.4 17.7 9.2 23.0 5.5 19.3 46.6 16.8 19.7 20.4 18.9 37.2 0.1 14.8 53.4 1.3 40.6 38.7 35.6 40.0 25.1 37.6 47.8 22.7 21.8 36.2 2.5 43.7 0.4 17.4 39.9 12.7 71.5 5.3 0.4 17.4 22.7 11.3 2.8 30.3 28.3 14.9 15.3 34.7 40.2 19.2 51.4 13.5 58.0 75.7 11.1 14.1 2.2 24.7 2.8 0.0 1.7 1.1 0.0 0.7 0.3 1.7 1.9 0.0 0.2 1.4 1.2 0.0 0.5 0.0 0.3 3.7 0.5 8.2 7.8 18.8 11.0 10.8 9.2 8.9 8.1 9.6 5.6 8.8 7.7 6.4 3.2 4.5 26.8 7.7 2.5 1.4 0.9 0.0 4.5 1.9 2.3 6.2 0.0 1.9 0.0 2.1 0.1 16.0 0.1 0.0 1.6 0.6 6.5 20.5 9.0 0.0 0.4 28.5 0.2 0.5 12.8 0.5 2.4 7.6 10.8 13.6 0.8 0.4 8.4 31.7 0.2 0.0 1.0 4.2 1.4 11.5 1.3 7.2 4.7 0.9 3.4 7.2 4.0 4.2 0.9 0.0 14.7 13.9 5.6 0.0 0.2 4.4 0.5 0.0 9.5 11.2 2.6 4.3 0.6 1.6 0.3 17.2 6.7 0.1 0.8 ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 263.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 284.7;Distal tubular cells: 172.1;Early spermatids: 261.4;Late spermatids: 373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028382: AB_2672574, HPA044950: AB_2679151" "unprognostic (1.34e-1)" "unprognostic (2.97e-3)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (5.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "prognostic favorable (5.33e-7)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" 66.0 89.9 87.5 23.3 94.4 27.4 30.2 97.1 115.2 30.0 102.8 44.9 35.3 22.5 29.4 30.1 27.3 25.8 221.0 82.9 107.7 97.1 95.3 21.9 27.9 85.8 85.6 28.8 41.2 121.5 43.8 32.3 85.3 32.2 48.1 63.9 48.4 29.0 221.0 20.1 35.2 32.3 80.7 21.6 42.1 41.5 90.6 37.8 37.1 263.4 28.5 26.4 20.2 82.2 57.8 46.1 61.1 54.8 65.1 52.3 51.0 42.2 52.6 62.0 49.7 37.2 24.5 34.1 55.2 53.6 54.9 43.6 97.3 54.7 83.1 75.0 76.7 60.2 54.5 65.0 52.4 60.2 3.4 51.4 64.3 66.5 57.7 49.2 39.3 62.8 28.2 65.4 48.0 52.3 89.3 33.3 96.3 49.8 68.8 38.1 16.5 74.3 71.4 45.2 71.8 53.8 71.4 74.9 114.6 70.0 69.3 83.8 34.4 21.1 52.1 43.1 58.5 80.6 78.9 23.2 34.7 23.0 40.6 0.0 1.6 4.1 2.1 2.8 2.7 1.8 2.2 2.5 1.6 1.2 3.1 1.4 1.3 5.6 1.2 1.2 4.5 1.2 87.5 94.4 97.1 115.2 82.9 107.7 85.8 85.6 85.3 80.7 90.6 82.2 12.6 3.2 18.6 31.0 22.3 9.4 21.2 9.7 27.3 34.0 27.8 19.4 284.7 31.5 13.1 31.3 27.1 64.0 14.5 26.7 172.1 22.1 261.4 15.6 15.4 13.2 19.2 31.3 37.1 20.1 30.0 28.5 29.0 15.9 15.9 40.6 10.4 39.8 39.2 47.1 48.5 38.1 16.2 21.6 12.9 373.7 19.0 16.1 24.9 15.9 14.6 39.2 15.5 28.1 33.7 11.3 18.0 26.7 36.3 15.2 30.2 119.1 10.2 29.2 26.3 25.1 28.9 45.2 40.4 34.3 13.5 46.9 19.2 55.1 42.2 21.9 AVPR1A AVPR1 ENSG00000166148 "Arginine vasopressin receptor 1A" P37288 12 63142759-63151201 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 24.1;Hepatocytes: 62.7;Sertoli cells: 78.9;Smooth muscle cells: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "ASC diff: 5.6;Karpas-707: 13.1;U-266/84: 9.8" "Group enriched" "Detected in some" 5 "basal ganglia: 7.0;hypothalamus: 3.8" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.82e-1)" "unprognostic (9.90e-3)" "unprognostic (2.90e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-3)" "unprognostic (3.79e-2)" "unprognostic (2.60e-1)" "unprognostic (3.58e-6)" "unprognostic (1.45e-1)" "unprognostic (7.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.38e-3)" "unprognostic (4.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.77e-2)" "unprognostic (4.66e-4)" 17.2 56.6 0.4 1.4 0.2 0.0 9.0 0.0 0.3 9.1 1.4 1.7 0.7 10.9 1.1 3.0 4.8 6.1 2.0 0.3 0.5 4.6 20.9 0.5 1.2 0.5 0.2 1.3 2.3 2.2 0.5 0.3 0.2 2.3 1.2 1.4 1.1 4.2 2.0 1.8 0.9 12.2 0.1 0.8 1.7 0.6 0.8 1.4 10.4 3.5 0.6 2.5 2.6 0.2 0.1 0.2 0.6 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.3 0.3 0.5 0.5 0.2 0.2 0.1 0.8 0.2 14.1 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.6 0.3 0.2 0.3 3.4 1.5 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 3.1 24.1 4.5 0.0 2.7 0.1 0.0 0.5 2.7 0.5 1.6 0.0 0.2 0.7 62.7 0.2 0.0 1.0 0.0 0.0 1.3 0.3 0.0 2.8 1.4 0.0 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 78.9 2.9 100.9 0.2 0.2 0.0 0.3 0.1 0.6 2.1 0.0 0.3 AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.1" "Group enriched" "Detected in some" 4 "Adipocytes: 48.0;Collecting duct cells: 49.7;Endothelial cells: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 7 "cerebellum: 3.9" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.6;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 29 "monocytes: 3.6" "Cell line enhanced" "Detected in some" "EFO-21: 3.2;SCLC-21H: 3.7;U-266/84: 3.7;U-698: 3.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 6.8" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 16: U-266 - Nucleosome" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" 5.2 0.2 0.1 0.2 0.0 0.8 3.1 3.9 0.1 1.0 0.5 0.8 0.6 0.9 0.1 0.6 1.6 1.0 5.1 0.1 0.0 8.1 0.0 1.3 1.0 0.3 0.5 0.2 0.6 0.7 0.1 0.2 0.4 0.7 0.2 0.0 0.7 0.6 3.1 1.5 0.8 0.8 0.1 0.3 0.7 0.2 0.1 0.4 0.9 4.0 0.3 0.8 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.6 3.2 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.1 1.2 0.6 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.8 1.0 0.1 0.0 0.0 1.4 0.6 1.4 0.0 0.0 3.7 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.6 3.7 3.6 0.0 0.9 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.1 0.0 3.9 0.1 0.1 0.0 0.3 0.5 0.4 0.1 0.1 0.2 48.0 3.2 1.3 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.5 0.4 1.5 0.0 0.0 49.7 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 1.3 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.6 0.8 0.0 0.0 0.1 1.3 0.0 0.1 0.5 0.0 0.1 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 196.4;Intestinal goblet cells: 47.4;Paneth cells: 72.5;Proximal enterocytes: 94.1;Undifferentiated cells: 57.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 23.5;RPTEC TERT1: 27.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.6" "HPA054092, HPA054684" Approved "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" 0.0 0.3 2.5 0.9 8.6 0.0 2.6 0.7 3.7 2.2 1.9 22.4 27.3 0.7 1.3 1.6 1.3 5.5 0.0 2.4 4.6 0.2 0.1 0.1 0.0 2.0 2.1 0.3 3.3 0.0 1.8 0.0 1.3 0.4 37.4 0.8 4.5 0.1 0.0 0.8 33.7 0.8 1.3 0.0 5.0 0.4 6.9 1.0 1.2 0.3 2.0 1.3 2.3 0.7 0.0 0.9 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 23.5 0.0 0.2 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 6.3 0.2 0.6 0.0 2.7 0.1 27.1 1.7 4.6 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.7 0.2 1.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 8.6 0.7 3.7 2.4 4.6 2.0 2.1 1.3 1.3 6.9 0.7 0.1 0.0 0.0 6.5 0.3 0.0 0.5 0.1 0.0 7.4 8.0 8.1 2.2 10.0 5.3 5.5 0.0 0.0 0.2 196.4 0.0 7.5 0.4 0.2 5.9 0.4 28.9 0.0 3.6 4.7 0.0 0.2 13.3 0.2 4.5 0.8 0.0 0.0 0.0 0.0 4.8 47.4 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 1.4 0.0 11.1 1.0 9.2 72.5 0.0 0.0 0.6 94.1 0.1 1.5 0.2 0.0 0.1 0.4 0.1 1.7 0.5 0.0 0.0 0.5 0.0 57.7 9.7 B4GALNT1 "beta1-4GalNAc-T, GALGT, SPG26" ENSG00000135454 "Beta-1,4-N-acetyl-galactosaminyltransferase 1" Q00973 12 57623409-57633239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 61.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.0;Excitatory neurons: 22.0;Horizontal cells: 21.9;Inhibitory neurons: 13.4;Smooth muscle cells: 7.5" "Cancer enriched" "Detected in many" 6 "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008968 Enhanced "Intracellular and membrane" NA NA 35000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA008968: AB_1078253" "unprognostic (3.18e-1)" "unprognostic (8.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.33e-3)" "unprognostic (2.54e-1)" "unprognostic (2.70e-3)" "unprognostic (3.73e-5)" "unprognostic (1.26e-2)" "unprognostic (1.72e-1)" "unprognostic (2.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.18e-14)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (1.44e-2)" "unprognostic (4.92e-4)" 1.9 1.1 26.9 1.9 29.7 0.0 0.7 29.3 61.1 1.3 0.6 2.7 0.5 2.1 2.7 0.7 0.7 1.1 3.3 34.9 21.9 0.8 0.4 0.6 0.6 16.7 11.8 0.3 0.3 0.3 1.7 0.4 20.5 2.6 1.2 4.2 1.8 5.0 9.5 0.6 1.2 2.5 8.1 0.6 0.9 0.7 19.1 0.3 1.2 7.2 1.0 1.2 1.6 29.9 7.5 38.2 18.2 38.7 0.3 0.1 0.4 3.0 11.3 19.0 17.5 2.8 21.9 3.0 47.9 13.2 35.9 3.3 15.3 2.1 5.2 67.4 2.6 1.8 10.1 9.9 0.4 3.1 4.1 0.1 0.9 11.0 0.5 6.7 0.2 11.4 8.7 34.8 2.4 13.5 2.5 0.1 13.0 0.9 7.7 0.1 27.1 8.0 0.1 0.1 34.9 12.3 3.1 1.1 0.4 0.9 7.0 3.3 0.0 22.8 28.1 24.0 26.1 37.0 34.0 2.6 28.9 2.3 45.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 26.9 29.7 29.3 61.1 34.9 21.9 16.7 11.8 20.5 8.1 19.1 29.9 0.8 0.0 0.0 2.6 0.0 0.4 0.0 0.0 0.0 10.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.0 0.8 0.0 0.0 22.0 0.2 0.2 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 21.9 13.4 0.0 0.0 0.0 0.3 0.7 2.8 0.1 3.6 2.8 2.6 0.7 0.0 4.5 2.7 0.5 0.0 3.0 0.0 0.1 0.0 0.2 0.0 2.6 6.6 0.6 7.5 1.6 4.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 B4GALNT2 "Cad, GALGT2, Sda" ENSG00000167080 "Beta-1,4-N-acetyl-galactosaminyltransferase 2" Q8NHY0 17 49132460-49176840 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Distal enterocytes: 3.9;Glandular and luminal cells: 5.2;Intestinal goblet cells: 11.5;Ionocytes: 4.1;Proximal enterocytes: 14.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 6.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015721 Approved NA NA "Cluster 9: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA015721: AB_1845245" "unprognostic (4.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.26e-3)" "unprognostic (2.03e-4)" "unprognostic (1.72e-2)" "unprognostic (2.62e-2)" "unprognostic (3.67e-2)" "unprognostic (7.67e-2)" "unprognostic (4.06e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.29e-5)" "unprognostic (3.53e-1)" "unprognostic (1.31e-1)" "unprognostic (7.81e-3)" "unprognostic (2.15e-1)" 1.2 1.3 1.4 7.8 1.0 4.7 0.7 6.6 2.1 0.2 2.3 33.5 2.1 1.1 0.6 0.7 0.4 2.2 1.0 1.7 0.8 9.1 0.9 1.4 2.2 0.7 0.4 1.0 1.7 0.1 0.0 0.7 0.5 0.7 14.2 7.5 2.0 0.3 0.8 2.8 8.4 2.7 0.0 2.2 5.9 1.5 1.1 0.2 5.9 0.1 0.8 0.6 0.0 1.5 0.9 1.7 1.7 3.0 0.1 0.0 0.9 1.3 1.0 0.0 0.1 4.0 1.4 2.1 2.1 0.0 0.6 0.9 0.7 0.1 0.2 1.8 1.8 2.2 5.1 2.1 0.0 1.1 3.5 0.2 1.4 0.3 0.2 0.7 0.0 1.6 1.3 3.3 0.0 1.1 1.4 1.5 2.1 0.3 0.8 2.5 0.7 0.6 5.4 1.4 1.4 1.5 0.6 0.7 0.6 1.7 1.8 1.4 0.6 2.2 1.3 1.3 0.7 2.6 0.9 2.3 0.7 1.4 0.9 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.4 1.0 6.6 2.1 1.7 0.8 0.7 0.4 0.5 0.0 1.1 1.5 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.3 0.5 0.0 0.9 5.5 0.0 0.0 0.0 3.9 1.9 0.6 0.7 0.6 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.5 4.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 14.8 0.1 0.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.1 B4GAT1 "B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT" ENSG00000174684 "Beta-1,4-glucuronyltransferase 1" O43505 11 66345374-66347629 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.3;Horizontal cells: 158.2;Muller glia cells: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015484 Uncertain "Intracellular and membrane" NA NA 57000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA015484: AB_1845235" "unprognostic (1.80e-1)" "unprognostic (7.20e-2)" "unprognostic (1.70e-1)" "unprognostic (3.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.45e-1)" "unprognostic (9.23e-2)" "unprognostic (1.59e-1)" "unprognostic (2.65e-2)" "unprognostic (3.43e-3)" "prognostic favorable (3.55e-5)" "unprognostic (2.20e-1)" "unprognostic (3.50e-1)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.76e-3)" 16.6 41.4 120.6 6.1 124.9 1.3 16.0 71.0 125.2 23.1 68.7 30.1 16.2 28.5 15.2 8.3 23.4 9.9 44.6 115.3 220.2 25.3 18.8 17.3 6.7 85.9 97.3 34.3 25.5 22.6 62.3 22.5 101.0 17.3 7.7 46.0 15.8 22.4 27.7 12.1 14.6 14.0 91.9 10.2 25.8 8.2 150.4 6.5 21.0 19.2 4.3 20.2 16.3 83.9 10.8 26.7 29.7 36.5 32.6 29.3 39.4 18.4 42.5 28.1 22.9 20.1 14.9 8.9 76.1 16.9 24.1 16.8 32.0 20.6 13.5 17.6 58.2 1.3 20.4 77.6 19.3 7.0 2.7 28.6 15.6 17.5 7.4 92.8 33.5 14.8 8.6 13.7 13.6 18.1 16.7 19.1 20.2 10.6 28.0 24.0 23.2 15.9 29.6 2.7 17.8 33.7 15.8 10.4 74.8 18.4 42.6 6.8 19.7 21.8 15.9 28.0 9.6 26.1 19.2 5.3 36.8 5.8 26.0 0.0 1.2 0.0 7.1 0.4 9.9 5.7 7.8 7.6 3.0 3.2 9.0 8.3 0.4 4.6 0.3 7.4 5.7 4.4 120.6 124.9 71.0 125.2 115.3 220.2 85.9 97.3 101.0 91.9 150.4 83.9 13.5 22.4 10.8 25.8 2.9 0.0 1.6 0.0 14.2 72.3 6.2 12.7 45.9 25.8 1.8 20.2 58.4 57.8 8.6 8.0 5.9 7.4 0.5 3.9 9.7 17.1 4.9 0.8 22.1 6.0 22.6 23.4 6.6 2.6 1.3 22.5 30.4 24.4 12.7 158.2 35.0 8.0 0.0 2.4 0.0 2.4 32.6 2.6 0.0 10.3 1.3 70.1 2.1 22.6 14.2 4.3 4.9 40.6 6.1 2.0 13.3 17.5 2.9 47.4 26.3 21.2 11.8 1.4 2.8 5.8 0.0 18.1 2.6 28.0 7.2 0.3 BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 300.9;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 67.8;Astrocytes: 198.2;Excitatory neurons: 131.4;Inhibitory neurons: 62.3;Muller glia cells: 132.4;Oligodendrocyte precursor cells: 125.7" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Cell line enhanced" "Detected in many" "AF22: 51.7;BJ hTERT+: 18.1;SCLC-21H: 27.9;SH-SY5Y: 20.5;U-87 MG: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" 9.3 15.6 196.7 2.1 209.2 3.4 7.0 182.2 226.6 1.6 108.2 3.1 0.9 1.7 0.4 0.7 3.8 1.6 3.1 201.1 206.8 4.3 2.9 7.3 1.4 240.0 237.4 3.3 2.1 0.4 25.9 5.3 219.5 1.1 1.6 19.4 1.0 0.9 2.0 2.0 2.7 1.8 229.2 14.5 2.4 1.3 300.9 0.6 4.5 1.4 0.8 2.5 1.4 205.3 0.5 3.0 51.7 0.5 0.5 14.9 0.0 2.6 18.1 0.1 0.2 0.5 0.1 0.2 0.5 10.1 0.2 0.8 0.9 0.1 0.1 0.1 3.1 0.5 0.8 0.1 1.2 0.0 1.1 3.0 2.9 0.6 0.0 2.7 0.4 0.1 0.0 0.4 0.1 0.4 0.0 0.2 1.3 0.4 1.0 0.2 0.3 1.2 0.0 0.1 27.9 20.5 0.6 0.0 0.1 4.5 0.2 0.3 3.0 16.0 1.0 0.4 1.0 0.0 0.2 0.2 75.7 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 196.7 209.2 182.2 226.6 201.1 206.8 240.0 237.4 219.5 229.2 300.9 205.3 67.8 0.0 1.8 198.2 0.3 5.5 0.7 4.5 0.6 2.1 2.0 1.1 0.8 17.2 5.9 0.0 0.0 0.1 2.1 0.3 7.9 32.0 2.9 15.6 2.3 33.4 17.8 6.1 131.4 25.6 0.1 1.6 0.0 34.0 0.0 0.0 23.6 0.8 0.9 0.0 62.3 3.4 22.4 1.3 6.2 8.7 1.5 2.1 14.2 18.7 4.6 132.4 2.1 125.7 46.1 4.1 1.2 0.0 0.8 0.8 0.1 0.1 21.7 3.3 0.0 2.1 8.1 0.1 0.1 0.3 4.0 0.0 1.3 0.3 0.1 1.1 BAG5 ENSG00000166170 "BAG cochaperone 5" Q9UL15 14 103556545-103562657 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 127.7" "Group enriched" "Detected in all" 13 "Early spermatids: 1734.2;Late spermatids: 1796.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016429 Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 83: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA016429: AB_1845261" "unprognostic (3.02e-2)" "unprognostic (2.98e-2)" "unprognostic (1.05e-2)" "unprognostic (6.26e-2)" "unprognostic (2.54e-1)" "unprognostic (5.22e-2)" "unprognostic (1.99e-3)" "unprognostic (2.78e-1)" "unprognostic (1.04e-1)" "unprognostic (4.77e-3)" "unprognostic (2.34e-1)" "unprognostic (3.80e-2)" "prognostic favorable (1.58e-8)" "unprognostic (2.51e-1)" "unprognostic (1.52e-1)" "unprognostic (3.69e-2)" "unprognostic (2.53e-1)" 24.6 11.4 12.7 15.1 13.0 27.8 18.7 15.9 16.7 14.7 15.6 14.8 12.3 16.1 12.6 21.8 16.0 12.9 13.3 13.5 13.2 15.9 11.9 15.5 17.1 12.6 12.4 12.1 12.2 14.0 10.8 14.4 12.8 14.0 14.6 18.4 16.5 14.2 13.1 19.3 12.1 15.1 12.4 18.3 14.9 127.7 12.2 14.9 23.7 13.5 19.1 15.3 12.6 14.3 26.2 22.1 30.0 27.1 27.5 26.5 33.1 26.0 22.6 22.6 19.9 18.0 32.7 47.3 24.5 30.2 20.6 38.4 24.2 34.7 35.6 19.9 15.8 31.3 25.3 16.2 17.4 42.7 31.3 19.3 43.7 23.2 29.3 20.7 24.0 34.4 25.2 34.8 31.2 35.1 37.4 19.9 17.8 43.8 27.4 40.1 34.4 21.6 37.3 58.3 33.0 22.3 34.9 30.3 23.6 20.1 38.9 21.8 28.4 24.4 19.9 37.9 31.2 21.4 34.4 52.7 27.5 22.9 30.9 28.7 13.4 11.9 9.3 14.8 11.9 6.8 11.0 9.0 14.1 7.8 12.8 11.1 9.0 13.0 21.4 5.9 10.6 12.7 12.7 13.0 15.9 16.7 13.5 13.2 12.6 12.4 12.8 12.4 12.2 14.3 51.5 44.8 24.3 10.4 29.4 69.0 44.8 33.3 47.8 37.9 32.9 28.8 21.8 17.2 44.5 35.0 27.1 25.4 40.0 26.5 66.5 24.7 1734.2 78.6 43.7 41.2 31.7 29.5 18.9 19.1 17.7 31.7 26.0 89.5 32.3 19.3 52.5 25.6 22.1 75.7 14.7 25.0 32.6 29.2 26.4 1796.9 49.7 24.4 32.0 11.2 23.6 49.6 36.0 9.0 20.3 27.1 15.2 67.0 18.5 45.2 18.4 31.7 43.3 36.2 32.9 30.3 27.0 129.7 40.4 60.5 89.8 40.8 33.3 33.1 24.3 62.1 BANK1 "BANK, FLJ20706" ENSG00000153064 "B cell scaffold protein with ankyrin repeats 1" Q8NDB2 4 101411286-102074812 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.2;lymphoid tissue: 96.4" "Cell type enriched" "Detected in many" 10 "B-cells: 455.9" "Cancer enhanced" "Detected in many" "prostate cancer: 6.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 14 "memory B-cell: 310.4;naive B-cell: 253.0" "Lineage enriched" "Detected in many" 16 "B-cells: 310.4" "Cell line enhanced" "Detected in some" "Daudi: 13.6;HEL: 10.6;HL-60: 9.6;U-266/70: 31.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037002 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 19000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA037002: AB_10672383" "unprognostic (1.59e-2)" "unprognostic (2.08e-2)" "unprognostic (6.43e-2)" "unprognostic (1.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.73e-2)" "unprognostic (4.89e-2)" "unprognostic (1.62e-2)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (4.25e-2)" "unprognostic (7.89e-2)" "unprognostic (2.80e-1)" "unprognostic (2.18e-1)" "unprognostic (2.75e-2)" "unprognostic (6.09e-3)" "unprognostic (1.75e-1)" 8.5 3.6 0.6 35.1 0.6 6.2 2.2 1.5 0.9 2.3 0.2 2.8 2.4 0.8 3.2 0.8 2.3 3.0 0.7 0.5 0.7 3.2 0.3 8.1 82.2 0.8 0.8 0.1 0.5 0.4 1.5 0.8 0.9 5.8 3.3 0.2 2.4 4.7 0.1 0.7 24.2 1.0 0.9 56.1 7.4 3.0 1.0 9.7 12.9 0.2 96.4 7.6 0.7 0.6 0.0 3.0 0.0 0.0 3.4 1.4 0.1 0.1 0.1 0.4 0.6 0.1 4.6 13.6 1.2 0.0 0.0 0.2 0.1 1.5 0.4 0.0 0.0 10.6 2.6 0.0 0.1 9.6 0.0 0.6 0.4 0.0 0.0 1.2 0.1 0.0 0.1 4.0 0.6 0.5 0.0 0.6 0.0 0.4 5.7 0.2 0.6 0.0 0.4 6.1 2.6 0.0 0.3 0.2 0.0 0.1 0.5 2.5 1.3 0.0 0.6 0.0 0.0 31.0 0.0 2.2 0.1 5.3 0.0 10.8 1.7 19.7 0.4 0.5 0.1 310.4 0.1 0.2 10.5 253.0 0.1 0.1 0.9 1.5 0.2 5.2 0.2 11.3 0.6 0.6 1.5 0.9 0.5 0.7 0.8 0.8 0.9 0.9 1.0 0.6 3.5 44.8 27.1 6.8 455.9 0.1 2.2 0.5 0.0 0.2 1.7 0.4 0.5 0.0 10.0 3.7 0.0 2.1 5.8 0.0 0.0 0.2 2.8 13.1 1.0 1.3 0.0 6.1 7.3 0.2 0.6 1.4 6.1 15.2 1.3 0.1 0.0 0.1 1.5 0.0 1.6 0.4 2.0 2.9 25.1 2.0 0.0 13.0 5.4 4.7 2.8 1.8 1.0 1.0 1.3 4.1 1.3 0.4 13.7 4.4 0.2 4.2 2.2 0.1 0.0 0.1 0.8 1.9 5.6 0.8 1.1 0.3 12.9 2.1 1.1 4.3 BATF "B-ATF, BATF1, SFA-2" ENSG00000156127 "Basic leucine zipper ATF-like transcription factor" Q16520 14 75522455-75546993 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.7;lymphoid tissue: 30.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 105.4;Breast myoepithelial cells: 73.9;granulocytes: 243.7;NK-cells: 103.0;T-cells: 116.5;Urothelial cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "T-cells: 130.3" "Cell line enhanced" "Detected in many" "HDLM-2: 368.9;MCF7: 134.7;RT4: 83.3;SK-BR-3: 64.8;U-937: 101.6" "Not detected" "Not detected" "HPA059588, HPA064962" Approved Enhanced Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA059588: AB_2684074, HPA064962: AB_2685392" "unprognostic (3.33e-3)" "unprognostic (4.87e-3)" "prognostic unfavorable (8.30e-4)" "prognostic favorable (5.35e-6)" "unprognostic (3.02e-2)" "prognostic favorable (7.91e-5)" "unprognostic (1.14e-2)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (6.72e-2)" "unprognostic (7.17e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (3.74e-9)" "unprognostic (4.74e-2)" "unprognostic (1.90e-1)" "unprognostic (1.41e-1)" "prognostic favorable (4.30e-4)" 5.5 1.3 1.0 20.5 1.8 21.7 7.8 1.0 1.4 2.2 1.1 3.0 2.6 1.3 1.1 2.9 1.9 5.8 2.4 1.0 1.2 1.4 2.9 8.0 30.6 1.5 1.4 0.5 0.9 8.0 0.5 4.1 1.7 5.5 1.4 0.0 6.5 1.8 0.4 2.9 9.7 2.3 1.2 26.9 7.8 0.6 2.2 7.2 1.9 1.0 20.4 18.2 2.9 1.5 4.7 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 368.9 0.0 7.5 0.0 1.6 11.5 10.0 36.3 0.1 0.0 0.0 0.0 0.0 0.0 8.1 2.0 10.3 0.0 134.7 4.7 30.8 0.2 54.9 0.0 1.1 0.0 6.3 0.0 83.3 0.1 0.0 0.0 64.8 2.7 0.0 6.1 18.7 0.0 0.0 0.0 4.4 0.3 32.8 36.9 0.3 0.0 101.6 0.1 3.6 25.5 8.2 55.0 13.7 43.4 21.3 59.7 74.2 25.2 17.5 23.1 50.4 14.4 21.3 13.2 2.9 130.3 27.8 1.0 1.8 1.0 1.4 1.0 1.2 1.5 1.4 1.7 1.2 2.2 1.5 2.9 9.6 29.3 0.0 17.1 5.4 50.8 5.7 0.6 0.0 105.4 73.9 0.3 1.5 13.5 3.7 0.0 0.4 36.9 0.0 0.0 0.8 0.5 0.9 0.6 5.0 0.0 7.2 0.2 2.5 0.4 4.4 10.2 1.9 243.7 0.0 2.5 0.7 61.3 0.0 0.1 0.0 34.6 15.4 10.7 0.6 0.0 21.7 5.4 1.0 16.7 0.0 103.0 0.0 0.1 11.0 0.1 0.0 29.9 22.1 0.0 0.2 12.8 0.0 0.0 1.0 2.0 0.0 0.1 0.4 3.4 1.1 116.5 0.2 0.5 74.3 BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" 294.1 213.9 171.5 100.9 175.5 151.3 210.9 171.8 213.9 139.5 202.5 157.7 133.3 127.4 228.9 214.0 151.0 118.0 123.5 183.0 192.1 160.7 185.5 144.5 111.8 190.8 187.5 130.9 266.4 193.7 123.5 143.3 195.3 154.6 166.5 63.9 179.7 177.7 81.9 187.3 143.8 155.0 183.4 138.5 129.3 117.3 186.9 99.7 161.4 75.5 134.6 177.9 145.8 185.0 505.5 482.4 128.0 650.6 593.8 179.1 295.3 269.9 287.5 291.6 371.6 386.8 361.9 315.9 1068.1 412.2 373.9 506.8 337.3 518.6 221.0 152.8 436.9 198.4 350.4 323.3 276.4 335.1 373.2 233.8 454.2 282.3 330.1 298.4 372.6 172.0 268.0 528.3 332.7 535.3 187.3 402.5 145.8 704.6 431.7 207.5 152.8 693.2 459.3 546.8 173.3 241.8 111.8 520.6 350.0 200.3 196.2 320.2 380.0 248.9 234.7 338.9 495.1 518.0 1120.1 397.3 460.9 402.6 223.7 630.5 484.2 489.1 507.5 535.7 454.7 436.1 504.5 507.4 420.7 463.6 439.1 474.7 624.5 449.8 632.3 666.9 457.1 1110.8 171.5 175.5 171.8 213.9 183.0 192.1 190.8 187.5 195.3 183.4 186.9 185.0 184.9 112.2 114.1 14.7 97.5 141.9 232.2 374.0 172.4 53.0 127.3 165.7 60.3 134.4 222.8 128.8 45.9 467.5 113.5 194.1 37.2 252.4 7.8 99.7 70.1 165.5 103.2 59.3 16.9 210.0 444.8 103.6 78.5 103.9 95.6 68.5 199.6 216.0 356.2 32.0 12.8 155.1 244.1 148.4 125.6 20.6 105.3 166.2 160.1 17.8 137.5 138.2 111.2 11.6 12.9 247.1 187.4 98.9 120.8 191.8 242.8 170.9 172.6 51.8 157.8 42.9 106.5 310.3 231.3 174.0 130.4 538.1 114.6 120.4 187.0 260.4 BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282" Approved Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: AB_2677929" "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavorable (9.11e-5)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favorable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" 34.7 22.3 3.5 4.2 5.8 0.0 27.9 16.9 6.6 37.7 6.3 34.4 15.8 39.2 2.6 22.5 25.3 9.4 47.1 2.3 7.9 47.3 34.2 38.8 2.1 3.9 1.9 19.7 32.4 5.9 29.5 14.1 2.3 25.6 3.5 1.3 25.5 5.7 93.8 18.2 33.1 3.8 0.0 33.7 44.6 34.3 4.2 0.9 26.8 6.8 1.1 24.9 26.2 15.8 21.8 36.8 17.5 6.0 6.7 6.3 34.1 29.5 17.1 20.9 16.4 46.5 32.1 1.9 38.2 33.3 23.6 18.2 6.1 34.0 6.0 0.1 20.0 0.0 23.7 37.2 16.7 0.1 15.1 19.1 16.3 25.3 12.5 12.3 57.9 0.0 20.0 1.0 12.6 48.9 0.1 1.3 23.4 16.1 24.0 0.8 7.9 8.2 19.1 27.9 21.4 31.5 28.7 6.6 11.2 8.4 15.0 5.4 53.6 34.4 29.5 8.8 44.2 8.0 4.7 0.7 22.2 0.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 16.9 6.6 2.3 7.9 3.9 1.9 2.3 0.0 4.2 15.8 30.1 22.4 6.9 9.4 1.2 28.0 59.7 36.8 12.0 26.5 20.3 14.4 22.9 31.5 21.8 22.0 6.2 46.8 0.7 75.7 27.4 51.9 19.0 13.7 27.9 49.2 34.8 0.0 13.1 61.8 25.7 21.1 71.9 22.5 8.9 15.0 46.8 21.0 6.0 13.5 11.7 42.1 12.2 1.4 6.3 26.8 16.4 2.1 32.0 10.3 0.6 12.9 0.0 19.1 31.2 68.5 59.6 33.4 1.4 58.4 57.4 38.9 13.1 6.8 19.7 8.5 38.5 20.6 17.1 12.5 17.6 36.1 2.2 10.9 33.7 62.7 BCAT1 BCT1 ENSG00000060982 "Branched chain amino acid transaminase 1" P54687 12 24810024-24949101 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 58.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 203.2;Early spermatids: 161.4;Exocrine glandular cells: 139.9;Langerhans cells: 265.8;Late spermatids: 370.3" "Group enriched" "Detected in all" 4 "endometrial cancer: 19.0;glioma: 10.7;lung cancer: 7.2;ovarian cancer: 24.0;testis cancer: 27.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 17.1" "Group enriched" "Detected in many" 10 "dendritic cells: 5.8;monocytes: 17.1" "Cell line enhanced" "Detected in many" "HDLM-2: 261.3;NTERA-2: 287.4;RH-30: 310.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048592 Uncertain NA NA 97000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" "HPA048592: AB_2680454" "unprognostic (1.90e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (3.05e-5)" "unprognostic (9.49e-3)" "unprognostic (4.22e-2)" "unprognostic (4.77e-3)" "unprognostic (1.97e-3)" "unprognostic (4.06e-1)" "prognostic unfavorable (1.38e-4)" "prognostic unfavorable (4.95e-4)" "unprognostic (5.44e-2)" "unprognostic (7.55e-2)" "prognostic unfavorable (8.54e-4)" 6.7 5.9 4.1 7.1 5.7 2.4 2.1 11.1 10.6 3.6 0.0 3.0 0.8 8.6 1.0 2.0 7.2 4.4 1.8 3.0 19.6 1.2 1.3 9.6 6.4 19.4 19.8 7.2 58.2 0.4 6.6 15.2 22.7 0.9 2.6 14.5 1.7 0.8 0.7 0.6 3.6 5.7 6.4 2.0 1.8 7.1 14.0 5.2 1.2 2.0 5.3 4.1 1.3 7.9 30.3 12.1 106.8 0.2 30.5 59.0 54.9 60.9 40.6 33.4 55.2 67.1 83.1 114.0 0.3 100.7 6.5 12.0 77.2 0.5 88.2 261.3 15.4 91.1 2.0 37.3 112.3 105.9 31.6 77.4 2.0 85.1 17.8 73.0 114.3 56.9 88.5 1.1 28.7 0.6 65.2 30.1 287.4 0.0 8.1 0.1 310.3 1.4 0.1 10.4 0.1 60.1 0.1 0.2 0.5 114.8 0.2 45.2 150.8 19.7 72.9 80.4 58.1 13.2 13.9 152.7 69.9 62.4 0.3 0.0 2.3 0.0 0.0 3.6 0.1 1.1 0.0 0.1 5.8 0.0 0.0 0.0 1.0 0.1 17.1 3.4 0.2 1.0 4.1 5.7 11.1 10.6 3.0 19.6 19.4 19.8 22.7 6.4 14.0 7.9 1.7 16.0 26.0 1.6 1.3 8.7 0.1 2.5 0.0 203.2 0.3 0.3 1.6 1.5 2.2 0.0 2.1 61.2 4.3 0.0 1.9 1.8 161.4 41.5 92.6 16.8 0.0 20.8 39.6 139.9 23.2 27.6 0.0 89.1 11.4 117.4 7.9 0.3 72.3 42.1 81.8 0.0 14.2 87.1 265.8 370.3 7.2 59.9 7.2 38.4 22.3 7.1 0.0 84.4 57.4 49.6 0.0 4.1 0.7 0.2 0.0 0.1 3.3 12.2 6.6 14.9 17.4 1.9 1.6 0.5 7.2 22.4 2.8 41.3 0.1 0.1 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BCL7B ENSG00000106635 "BAF chromatin remodeling complex subunit BCL7B" Q9BQE9 7 73536356-73557690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Wnt signaling pathway" "Allergen, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049943, HPA058069" Approved Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA049943: AB_2680963, HPA058069: AB_2683594" "unprognostic (2.79e-2)" "unprognostic (2.87e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-1)" "unprognostic (3.54e-3)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" "unprognostic (4.84e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-1)" "unprognostic (5.37e-2)" "unprognostic (9.43e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.09e-1)" "unprognostic (3.55e-1)" "unprognostic (5.41e-2)" "unprognostic (1.32e-1)" 35.6 23.8 34.9 18.7 35.0 90.0 18.5 28.1 43.5 16.3 28.3 32.6 21.8 15.5 17.4 27.5 16.6 22.5 49.5 36.5 34.1 21.9 25.1 27.4 24.4 30.6 31.2 9.0 25.6 30.3 20.9 21.7 29.7 17.8 16.4 17.7 16.0 23.5 66.0 11.1 23.6 29.8 28.3 23.0 20.6 20.5 33.4 22.4 22.1 55.8 19.4 33.4 11.4 34.3 67.8 46.9 26.7 47.8 21.5 34.0 27.1 56.1 58.9 58.0 52.9 52.0 73.8 56.7 14.0 58.7 84.7 30.4 19.4 45.7 42.7 73.9 27.5 31.5 28.7 28.0 61.3 54.3 85.3 22.8 45.0 59.5 58.7 23.9 38.4 31.7 50.6 65.0 41.6 79.5 93.0 71.2 46.5 43.0 67.7 49.2 28.6 67.6 46.5 51.8 59.7 57.9 49.6 85.0 62.3 11.3 53.0 73.3 39.6 69.8 44.7 47.9 84.1 37.0 35.9 105.2 68.7 82.8 89.0 13.7 13.3 19.7 11.4 15.8 13.8 11.7 13.1 15.3 13.5 17.6 13.7 11.1 6.5 21.2 20.3 15.9 11.4 8.3 34.9 35.0 28.1 43.5 36.5 34.1 30.6 31.2 29.7 28.3 33.4 34.3 50.4 32.1 20.7 6.8 59.8 64.6 81.9 18.7 39.3 27.5 37.4 32.1 29.5 24.3 17.5 16.5 6.2 72.5 55.9 63.3 54.8 46.7 8.0 35.4 16.8 37.3 34.6 17.9 10.3 45.8 43.6 30.4 21.9 31.6 32.4 21.5 34.2 18.1 51.0 42.1 8.8 40.6 32.6 37.5 46.4 6.7 25.7 48.3 32.0 6.5 41.1 32.4 62.8 6.0 10.0 67.9 58.3 30.5 35.7 61.6 50.4 47.0 15.7 21.8 46.0 52.4 46.7 64.1 71.6 28.7 57.7 101.8 58.3 27.3 37.6 74.1 BHMT2 ENSG00000132840 "Betaine--homocysteine S-methyltransferase 2" Q9H2M3 5 79069767-79090069 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "kidney: 333.1;liver: 429.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Hepatocytes: 201.2;Proximal tubular cells: 408.6" "Group enriched" "Detected in many" 14 "liver cancer: 79.6;renal cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 17.5;Hep G2: 78.2;hTEC/SVTERT24-B: 46.0;U-87 MG: 18.6" "Not detected" "Not detected" HPA044573 Enhanced NA NA 1900000 "Cluster 17: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044573: AB_10795044" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-2)" "unprognostic (3.76e-2)" "unprognostic (4.40e-2)" "unprognostic (2.90e-3)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.87e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-2)" "unprognostic (5.05e-2)" "unprognostic (1.49e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-3)" 31.3 16.6 5.6 3.0 6.0 0.3 15.5 4.5 5.0 8.5 14.2 15.7 1.7 12.1 37.6 7.6 7.6 7.4 13.6 4.9 7.3 333.1 429.9 3.1 1.3 5.2 7.0 7.8 1.8 0.5 12.3 0.4 6.2 12.0 2.4 1.3 2.1 14.4 10.2 2.4 6.1 13.0 4.7 0.6 9.1 3.8 6.9 0.9 18.8 4.8 1.0 18.1 3.8 4.7 0.0 0.2 0.1 0.1 8.5 6.0 2.8 7.8 17.5 4.0 7.7 0.0 0.1 0.1 0.1 9.7 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.4 0.4 78.2 6.6 0.4 0.1 7.3 0.0 46.0 0.0 7.9 0.0 0.0 0.4 0.4 1.1 0.0 0.1 0.3 0.1 0.0 0.2 0.1 0.5 0.1 0.0 0.2 2.2 0.1 0.5 0.0 0.1 0.5 0.1 0.2 0.0 0.3 0.1 0.3 0.1 0.1 0.1 0.3 18.6 0.4 0.1 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.3 0.0 0.1 0.0 0.0 5.6 6.0 4.5 5.0 4.9 7.3 5.2 7.0 6.2 4.7 6.9 4.7 1.4 6.4 0.5 6.2 1.2 0.8 0.4 0.1 0.0 1.5 0.2 0.1 4.4 1.5 0.0 46.0 2.1 0.2 0.0 0.0 95.9 0.1 0.5 0.4 11.7 2.9 1.2 2.7 4.1 0.0 0.4 17.3 0.0 0.4 0.0 4.5 2.5 201.2 0.3 0.0 0.6 0.1 0.0 4.4 1.2 1.3 27.4 2.5 0.0 11.2 0.3 4.2 0.0 2.0 0.6 0.0 0.0 37.2 0.1 0.4 0.0 408.6 0.1 1.2 6.6 6.2 3.1 0.4 0.5 0.1 1.0 0.3 2.2 30.0 0.0 1.0 BICC1 ENSG00000122870 "BicC family RNA binding protein 1" Q9H694 10 58512872-58831435 "Disease related genes, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 120.5;Cholangiocytes: 158.7;Collecting duct cells: 86.5;Ductal cells: 98.5;Fibroblasts: 79.6;Microglial cells: 165.8;Proximal tubular cells: 148.2" "Group enriched" "Detected in all" 4 "pancreatic cancer: 9.2;renal cancer: 25.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 6.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "A549: 59.1;BJ hTERT+: 61.4;CACO-2: 93.1;RPTEC TERT1: 140.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070797 Approved Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol Centrosome "HPA070797: " "unprognostic (1.27e-1)" "unprognostic (1.57e-3)" "unprognostic (3.61e-1)" "unprognostic (1.96e-1)" "unprognostic (6.09e-3)" "unprognostic (1.72e-1)" "unprognostic (9.98e-3)" "unprognostic (1.79e-2)" "unprognostic (6.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.40e-3)" "unprognostic (7.16e-2)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" "unprognostic (4.19e-2)" "unprognostic (6.23e-2)" "unprognostic (2.94e-2)" 10.6 6.1 0.3 4.0 0.5 0.3 8.7 0.0 1.6 5.8 1.9 4.5 1.2 4.9 4.0 3.5 7.5 11.6 10.5 0.6 1.0 28.6 2.4 5.8 2.4 1.2 0.6 13.9 16.9 0.8 3.6 3.6 0.2 3.8 4.1 1.4 4.3 4.2 7.6 6.1 2.7 4.7 1.2 2.9 2.7 3.1 0.7 1.4 4.6 6.2 2.7 5.5 5.6 0.7 0.0 59.1 0.8 0.0 17.9 23.0 0.0 38.5 61.4 34.4 40.4 93.1 12.3 0.0 39.8 39.3 8.8 0.8 6.1 7.0 47.4 0.1 5.9 0.0 7.4 0.1 11.5 0.0 0.0 36.0 2.2 26.9 28.6 42.3 0.1 0.0 0.0 0.2 13.4 0.1 0.0 0.0 0.5 0.0 3.8 0.0 14.3 0.0 140.8 7.1 0.2 7.3 0.1 0.4 3.4 2.4 0.0 0.6 0.0 8.2 7.7 1.4 5.0 0.0 0.0 0.1 23.8 0.0 7.8 6.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.5 0.1 0.0 0.3 0.5 0.0 1.6 0.6 1.0 1.2 0.6 0.2 1.2 0.7 0.7 4.1 0.0 0.5 120.5 1.5 7.1 1.3 1.3 0.6 0.6 1.1 4.3 3.3 158.7 1.7 86.5 0.0 0.4 0.1 0.3 78.2 98.5 5.2 43.8 14.4 1.4 3.6 0.0 70.4 3.5 0.2 79.6 0.5 7.2 0.0 4.2 3.3 1.4 3.5 0.0 37.2 1.2 0.0 0.6 18.5 3.2 71.1 1.7 21.4 165.8 1.1 10.1 0.0 25.6 2.7 35.3 1.2 50.0 0.3 2.4 0.0 148.2 14.1 0.2 6.6 40.0 9.8 0.1 3.9 0.3 4.7 4.1 1.5 8.7 1.6 0.1 BIK NBK ENSG00000100290 "BCL2 interacting killer" Q13323 22 43110750-43129712 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 329.3;Club cells: 215.6;Ionocytes: 443.5;Paneth cells: 140.5;Respiratory ciliated cells: 204.1;Urothelial cells: 175.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 72.9;plasmacytoid DC: 58.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 89.9;CAPAN-2: 44.3;Daudi: 44.2;U-698: 172.1" "Not detected" "Not detected" HPA051360 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051360: AB_2681453" "unprognostic (1.18e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.09e-1)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.86e-3)" "unprognostic (3.27e-1)" "unprognostic (2.71e-2)" "unprognostic (4.36e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.45e-5)" "unprognostic (1.38e-2)" "unprognostic (2.56e-1)" "unprognostic (4.08e-2)" "unprognostic (3.04e-1)" 0.2 2.3 0.2 4.1 0.4 4.1 4.9 0.7 0.3 2.8 0.0 8.5 3.6 0.2 1.2 11.3 3.0 3.1 0.3 0.5 0.0 3.8 0.5 1.4 11.6 0.0 0.0 0.3 2.5 1.6 1.0 0.1 0.1 11.4 5.2 0.2 17.5 0.5 0.0 3.5 5.3 0.2 0.0 2.9 13.4 2.0 0.1 1.4 1.8 0.1 11.2 2.6 6.5 0.0 89.9 0.7 0.2 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 28.8 44.3 44.2 4.2 0.0 0.9 19.5 4.8 1.9 0.0 0.7 6.7 0.1 0.6 4.9 0.7 21.2 4.1 0.0 8.8 0.0 0.0 0.3 0.2 9.5 0.3 2.0 0.0 22.9 16.9 28.9 6.7 24.2 7.3 0.2 0.1 20.6 0.9 2.6 1.7 0.0 3.1 8.2 6.5 3.1 1.6 28.9 0.8 0.1 2.4 0.2 1.0 10.4 17.1 172.1 0.0 2.2 0.2 1.8 2.9 72.9 2.7 0.7 4.3 17.1 9.5 4.2 10.4 11.7 6.4 3.5 11.3 0.9 0.8 58.6 7.1 6.3 0.2 0.4 0.7 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 4.2 0.0 9.3 12.6 32.7 329.3 3.4 0.0 39.7 24.1 0.7 17.2 215.6 7.3 0.0 1.4 7.9 43.0 7.9 62.2 0.3 17.7 0.8 2.3 50.6 5.7 0.3 16.2 1.2 0.9 90.7 9.1 0.0 0.1 5.3 0.7 0.9 0.0 0.2 52.9 443.5 1.4 4.8 0.4 0.0 4.0 35.6 0.0 6.4 0.0 1.0 0.0 0.1 105.2 140.5 0.7 79.7 53.1 10.2 15.7 204.1 0.0 0.0 0.0 14.9 0.2 11.0 16.1 11.8 1.0 12.9 0.3 53.9 175.3 BIN1 "AMPH2, AMPHL, SH3P9" ENSG00000136717 "Bridging integrator 1" O00499 2 127048027-127107288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 2105.3;tongue: 803.2" "Cell type enhanced" "Detected in all" "Hofbauer cells: 164.9;NK-cells: 176.1;Oligodendrocytes: 186.4;Proximal tubular cells: 255.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 186.6;MAIT T-cell: 163.9;memory B-cell: 165.9;memory CD4 T-cell: 192.1;memory CD8 T-cell: 187.4;naive B-cell: 181.2;naive CD4 T-cell: 177.1;naive CD8 T-cell: 171.1;NK-cell: 178.9;T-reg: 249.8" "Group enriched" "Detected in all" 9 "B-cells: 181.2;NK-cells: 178.9;T-cells: 249.8" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001945, HPA003894, HPA005437" Enhanced Supported Cytosol NA NA 430000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB001945: , HPA003894: AB_1845360, HPA005437: AB_1078284" "unprognostic (2.20e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" "unprognostic (9.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-3)" "unprognostic (1.26e-2)" "unprognostic (2.57e-1)" "unprognostic (2.41e-3)" "unprognostic (3.22e-3)" 43.7 93.2 178.8 25.7 232.8 12.0 37.3 162.6 209.6 53.8 85.9 35.2 17.4 38.7 16.8 33.5 53.5 22.6 16.5 174.2 160.6 83.4 34.7 22.7 41.0 204.2 194.8 34.4 21.5 19.6 41.0 23.5 189.8 58.1 13.1 53.7 42.6 24.0 2105.3 14.8 31.5 19.6 155.4 54.7 45.0 10.4 199.2 18.4 28.5 803.2 27.5 89.0 36.6 310.5 52.0 27.9 32.8 39.3 95.9 76.5 11.4 15.3 33.1 35.8 23.4 107.6 31.3 0.0 46.0 28.9 20.8 6.8 14.6 25.0 9.5 5.9 4.1 15.1 46.9 7.1 86.2 0.2 2.8 70.2 6.1 77.3 14.0 46.4 49.1 5.1 3.2 1.6 44.8 1.1 4.9 43.3 24.8 114.2 31.4 11.8 36.3 4.8 126.7 0.1 22.4 61.9 55.5 21.2 17.7 34.7 1.3 9.7 59.3 40.9 39.9 52.8 52.1 1.3 1.4 0.3 60.3 2.6 19.2 1.2 3.1 0.6 186.6 2.0 163.9 165.9 192.1 187.4 15.1 181.2 177.1 171.1 6.0 178.9 3.2 21.5 249.8 133.5 178.8 232.8 162.6 209.6 174.2 160.6 204.2 194.8 189.8 155.4 199.2 310.5 15.6 9.6 10.0 10.7 80.1 18.6 10.0 3.3 1.2 144.1 10.7 9.1 5.6 44.3 5.5 14.7 125.1 1.8 98.3 18.6 37.2 15.2 16.1 11.7 46.2 21.9 46.0 11.6 36.9 29.4 4.2 68.7 29.0 19.0 2.5 28.7 15.0 18.3 164.9 30.3 47.2 28.0 10.2 27.0 62.3 55.8 78.6 50.1 23.2 58.1 10.4 25.3 176.1 11.6 186.4 16.7 18.1 30.5 14.6 26.2 14.3 255.7 1.4 133.4 13.1 75.7 28.8 2.6 10.9 1.6 8.9 2.9 98.2 40.0 50.1 9.8 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564599 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 39.1;lymphoid tissue: 46.7" "Cell type enriched" "Detected in some" 11 "B-cells: 116.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 183.4;naive B-cell: 131.5" "Lineage enriched" "Detected in many" 5 "B-cells: 183.4" "Cell line enhanced" "Detected in some" "Daudi: 106.6;REH: 29.9;RPMI-8226: 38.5;U-698: 48.6;U-87 MG: 22.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB005093, HPA069571" Approved Uncertain Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "CAB005093: AB_2274756, HPA069571: AB_2732137" "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.1 0.0 9.1 0.0 2.6 0.2 0.0 0.0 0.0 0.0 2.6 0.5 0.1 0.0 1.2 0.2 0.5 0.1 0.0 0.0 1.2 0.7 0.8 29.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.0 0.7 0.0 0.3 0.0 39.1 0.1 0.0 46.7 2.1 0.1 0.0 2.5 1.2 0.0 27.9 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 29.9 0.0 38.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 5.4 10.2 48.6 22.7 0.0 0.0 0.2 0.1 0.2 2.0 0.0 37.9 183.4 1.4 4.6 0.1 131.5 0.9 0.4 0.7 0.1 0.1 17.5 1.8 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 116.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.1 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 4.0 0.1 0.1 0.0 BLOC1S1 "BLOS1, BORCS1, GCN5L1" ENSG00000135441 "Biogenesis of lysosomal organelles complex 1 subunit 1" P78537 12 55716037-55720087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 1180.5;Proximal tubular cells: 719.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA021381 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021381: AB_2228026" "unprognostic (1.27e-1)" "prognostic favorable (2.77e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (1.10e-1)" "unprognostic (2.40e-1)" "unprognostic (1.59e-1)" "unprognostic (6.77e-2)" "unprognostic (2.22e-1)" "prognostic favorable (2.19e-4)" "unprognostic (6.51e-3)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-2)" "unprognostic (1.83e-2)" 125.6 168.5 248.4 81.5 256.8 223.7 112.5 261.4 294.0 94.0 248.6 184.6 145.3 118.9 151.1 177.1 133.4 77.0 169.7 249.4 260.6 196.1 219.3 113.0 107.5 259.1 254.9 93.6 110.1 175.6 109.6 71.6 258.7 113.1 167.5 81.7 107.3 77.1 309.8 114.8 155.4 99.7 258.9 174.9 164.8 55.0 250.9 146.8 118.8 201.1 111.7 125.2 106.2 271.6 134.9 258.3 133.7 113.3 170.6 217.1 75.7 93.7 154.4 112.9 111.8 148.5 267.3 148.6 166.5 194.6 95.2 91.7 70.8 132.4 110.9 142.5 160.5 84.6 220.5 224.9 163.6 104.5 177.7 139.8 137.3 108.2 83.1 145.8 152.4 172.0 77.5 221.0 183.3 294.0 164.3 123.8 84.6 219.1 134.2 110.9 129.9 163.3 182.9 164.2 85.1 141.6 85.1 86.0 150.5 93.2 177.5 169.2 114.2 87.2 142.7 96.5 74.0 99.4 126.2 134.6 158.8 97.2 121.8 612.0 471.8 746.5 238.6 543.1 162.2 345.1 224.4 239.8 486.6 326.5 160.9 201.1 631.4 221.7 586.1 409.0 318.2 637.9 248.4 256.8 261.4 294.0 249.4 260.6 259.1 254.9 258.7 258.9 250.9 271.6 155.2 16.0 20.7 0.0 110.4 83.1 120.0 143.2 61.5 51.6 123.8 158.5 37.6 160.2 92.0 160.0 25.0 98.1 159.5 439.5 369.8 207.3 53.7 123.9 60.6 92.1 99.5 191.3 0.0 320.7 182.3 105.1 103.0 88.6 20.2 77.9 122.4 378.7 430.7 30.3 0.0 266.8 179.0 403.1 213.2 213.9 134.2 238.6 176.1 0.0 347.9 192.0 230.7 0.0 0.0 291.0 409.3 98.9 66.9 122.6 1180.5 719.6 114.2 92.9 78.9 133.9 208.5 46.9 55.0 86.6 88.9 73.2 111.5 77.4 256.7 180.7 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BNC2 "BSN2, FLJ20043" ENSG00000173068 "Basonuclin 2" Q6ZN30 9 16409503-16870843 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 26.9;ovary: 31.7;smooth muscle: 31.7" "Cell type enhanced" "Detected in many" "Astrocytes: 46.7;Leydig cells: 90.1;Microglial cells: 230.5;Peritubular cells: 67.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "gdT-cell: 2.5" "Lineage enriched" "Detected in single" 5 "T-cells: 2.5" "Cell line enhanced" "Detected in many" "HSkMC: 31.9;Karpas-707: 40.4;RPMI-8226: 28.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA018525, HPA059419" Approved Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA018525: AB_1845402, HPA059419: AB_2732637" "unprognostic (2.68e-1)" "unprognostic (2.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.14e-2)" "unprognostic (1.56e-2)" "unprognostic (5.07e-2)" "unprognostic (2.81e-2)" "unprognostic (2.50e-1)" "unprognostic (1.94e-2)" "unprognostic (6.05e-2)" "unprognostic (5.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (6.74e-2)" "unprognostic (1.14e-3)" 5.6 1.0 1.4 3.7 2.5 0.7 3.3 2.3 4.4 12.1 8.2 10.1 1.3 26.9 2.1 4.6 18.4 7.2 2.9 2.6 2.7 6.4 0.3 3.1 0.8 4.7 6.0 31.7 0.5 2.9 1.7 3.4 3.9 3.7 3.0 0.8 1.3 4.8 3.5 3.4 3.3 31.7 3.5 0.7 3.0 6.9 4.7 2.5 2.1 1.9 1.1 6.3 5.8 4.9 0.3 1.7 1.2 0.1 17.5 21.1 2.7 11.4 19.5 7.8 6.4 0.1 0.0 0.0 3.7 7.8 5.8 0.1 5.1 0.0 7.9 0.2 2.0 0.1 5.3 0.0 13.4 0.1 0.5 31.9 0.0 16.6 0.1 13.7 18.0 0.0 0.0 40.4 11.1 0.0 0.0 2.8 6.6 0.1 10.2 0.0 12.5 28.0 6.0 0.3 0.2 1.0 0.1 0.1 18.6 8.3 0.1 0.0 17.7 18.6 13.5 15.1 20.9 0.2 0.0 0.1 7.6 2.5 2.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 1.5 1.4 2.5 2.3 4.4 2.6 2.7 4.7 6.0 3.9 3.5 4.7 4.9 5.5 0.0 2.2 46.7 0.0 10.1 0.6 0.0 33.6 8.2 0.2 0.4 4.8 0.0 0.6 0.0 0.0 3.2 10.7 0.1 0.0 1.0 7.2 2.2 9.1 10.5 0.0 0.0 1.6 0.4 1.2 38.6 3.1 2.0 22.2 25.1 10.4 0.3 7.3 0.0 1.9 1.1 6.1 1.6 2.3 4.5 90.1 4.2 10.6 230.5 0.1 2.6 30.9 1.0 1.6 0.1 0.0 67.7 3.9 0.7 5.7 35.5 0.7 0.3 6.6 31.5 5.1 0.9 13.5 5.7 5.5 1.2 3.1 36.5 1.8 0.1 BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" 130.6 53.4 42.7 37.2 60.4 192.6 77.9 55.6 62.0 63.9 38.9 39.6 22.2 52.8 66.3 48.3 50.5 54.7 63.2 50.0 49.6 79.4 45.4 62.9 39.4 60.7 54.0 119.7 20.1 55.1 25.4 104.5 58.4 44.4 28.2 146.5 44.1 64.4 38.9 71.5 28.4 51.3 46.6 40.7 28.9 68.6 48.8 39.9 41.9 31.7 52.1 48.9 49.5 80.8 90.6 33.8 79.1 53.9 214.5 134.0 66.8 89.0 259.9 81.9 179.6 15.3 42.7 27.7 82.5 169.0 113.4 44.8 39.6 114.5 270.0 17.8 21.8 114.9 32.0 26.9 119.3 10.3 191.1 162.5 89.2 92.9 55.3 269.2 106.2 66.9 52.6 65.0 173.7 39.1 72.7 38.5 26.2 56.7 36.6 38.4 99.9 55.6 85.3 58.3 83.9 74.4 43.2 8.8 70.0 85.9 43.7 21.7 140.4 152.2 64.6 96.2 20.5 93.2 46.0 36.8 232.6 20.6 35.1 334.9 298.3 182.9 39.5 154.8 34.9 68.4 58.4 43.3 166.9 78.0 89.3 65.5 369.0 47.6 104.1 38.0 86.1 239.3 42.7 60.4 55.6 62.0 50.0 49.6 60.7 54.0 58.4 46.6 48.8 80.8 118.3 86.6 157.4 28.7 72.2 98.8 56.0 231.7 82.6 142.5 90.6 85.3 34.0 50.1 126.4 103.0 33.3 33.2 55.6 32.7 49.0 115.4 194.1 173.5 140.8 101.2 120.6 913.9 50.6 39.1 166.5 179.9 38.7 341.2 120.9 96.5 167.0 32.2 132.1 82.4 39.4 46.8 118.0 221.3 300.4 206.7 320.3 233.6 106.7 30.0 165.0 406.4 32.0 29.1 75.8 154.1 39.8 347.5 64.6 83.6 44.0 306.4 107.6 64.0 144.7 59.1 183.9 154.4 110.7 65.4 126.6 162.5 67.0 117.6 27.6 79.3 BOK "BCL2L9, BOKL, MGC4631" ENSG00000176720 "BCL2 family apoptosis regulator BOK" Q9UMX3 2 241551424-241574131 "Plasma proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 218.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 100.8;Oligodendrocytes: 47.0;Proximal tubular cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Cell line enhanced" "Detected in many" "TIME: 65.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (6.16e-2)" "unprognostic (3.01e-2)" "unprognostic (1.24e-3)" "unprognostic (6.30e-2)" "unprognostic (8.63e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-3)" "unprognostic (1.16e-2)" "unprognostic (8.45e-2)" "unprognostic (2.33e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "prognostic favorable (1.09e-9)" "unprognostic (9.48e-3)" "unprognostic (6.81e-2)" "unprognostic (2.46e-1)" "unprognostic (1.09e-1)" 90.6 7.1 88.4 6.2 138.6 0.4 37.7 110.4 110.3 15.6 51.0 38.0 8.1 34.2 16.3 29.5 18.1 22.7 6.3 77.0 87.8 20.5 97.0 20.1 3.7 146.6 120.6 9.9 16.3 3.8 4.7 5.7 127.1 28.5 5.0 1.2 11.8 25.5 2.6 20.0 9.4 20.4 98.5 6.5 21.5 7.7 115.4 1.1 11.0 3.2 3.4 34.9 18.6 218.8 36.0 8.8 15.7 36.2 26.3 15.6 4.4 28.6 11.3 36.9 37.9 16.2 14.6 0.1 9.7 51.0 9.0 32.9 1.7 28.9 13.8 0.1 0.3 0.1 9.3 42.2 21.8 0.2 1.3 15.9 29.2 15.5 4.4 27.8 44.6 2.4 6.4 0.1 36.7 46.0 0.2 0.2 9.9 40.0 26.8 0.4 25.9 0.2 24.2 0.9 14.0 5.4 13.2 8.5 23.3 18.3 24.4 1.3 65.0 0.1 52.8 0.7 3.2 0.1 0.1 0.1 0.1 0.0 2.1 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.7 1.0 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.6 88.4 138.6 110.4 110.3 77.0 87.8 146.6 120.6 127.1 98.5 115.4 218.8 22.5 6.4 32.1 0.3 0.5 7.1 11.5 8.6 5.2 0.2 19.4 10.5 10.2 32.9 6.3 11.0 0.0 2.0 2.5 5.8 15.6 23.2 0.2 6.6 17.6 15.6 11.4 5.3 0.8 11.1 10.5 10.9 5.6 14.4 0.0 2.6 12.5 100.8 0.7 0.0 1.5 3.7 2.0 4.7 1.2 1.5 6.2 0.7 1.8 4.7 0.0 3.9 6.2 7.5 47.0 27.7 2.8 10.5 0.9 26.3 7.1 41.9 1.5 1.3 0.0 11.7 11.2 0.3 8.2 19.8 12.8 6.2 1.6 3.4 6.1 15.1 BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.6;Cardiomyocytes: 53.8;Cytotrophoblasts: 18.0;dendritic cells: 16.2;Extravillous trophoblasts: 91.8;Hofbauer cells: 26.6;Syncytiotrophoblasts: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 37.6 37.3 14.8 16.1 19.9 12.4 19.3 19.2 19.8 25.5 8.9 17.4 13.3 21.9 16.2 19.1 13.4 16.5 29.4 16.0 17.9 23.4 36.2 17.2 12.3 17.2 17.6 11.8 19.6 35.6 13.7 24.9 17.7 31.0 17.6 19.7 21.9 23.6 37.4 14.3 12.7 25.7 15.3 15.5 16.9 16.5 18.0 15.4 27.1 30.1 13.3 22.4 12.2 29.3 42.4 34.5 26.0 26.9 78.2 53.3 35.7 62.9 60.9 44.1 38.3 17.4 29.2 26.3 47.0 67.3 31.2 33.7 31.8 42.5 65.0 36.4 22.7 51.4 23.0 31.2 48.5 33.0 35.1 43.2 41.6 39.7 63.9 40.8 59.5 24.3 22.5 46.1 48.9 22.1 40.6 19.8 19.2 48.1 12.7 27.9 23.4 29.7 46.0 24.9 10.1 28.1 35.3 42.9 36.3 27.1 38.4 23.9 50.1 59.3 34.2 59.2 45.8 47.5 42.5 27.8 81.0 27.0 37.3 1.8 0.9 0.5 0.9 0.6 0.7 0.7 0.6 0.5 0.7 0.9 0.6 1.1 2.5 3.2 2.6 1.0 0.4 0.3 14.8 19.9 19.2 19.8 16.0 17.9 17.2 17.6 17.7 15.3 18.0 29.3 22.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 18.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 91.8 14.4 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 33.8 1.8 0.0 0.0 0.0 BRAT1 "BAAT1, C7orf27, MGC22916" ENSG00000106009 "BRCA1 associated ATM activator 1" Q6PJG6 7 2537810-2555694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029455, HPA076508" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA029455: AB_10600761, HPA076508: AB_2686803" "unprognostic (2.53e-1)" "unprognostic (2.24e-1)" "unprognostic (1.19e-2)" "unprognostic (7.04e-3)" "unprognostic (6.07e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (2.03e-1)" "unprognostic (1.76e-1)" "unprognostic (2.46e-1)" "unprognostic (1.10e-3)" "unprognostic (4.69e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (5.37e-2)" "unprognostic (3.12e-2)" "unprognostic (8.88e-2)" "unprognostic (3.71e-2)" 17.4 31.0 10.7 6.8 10.9 7.9 17.8 10.4 14.3 22.5 9.6 16.2 8.8 19.4 2.2 15.1 19.2 3.7 14.5 10.4 11.2 15.2 20.7 12.2 7.2 13.5 11.4 21.6 20.2 5.2 19.8 4.5 10.1 24.5 1.3 0.9 17.4 6.6 14.8 21.6 16.6 2.5 10.6 21.1 19.6 31.5 11.2 5.0 18.7 3.7 2.1 17.6 18.8 10.5 35.1 31.1 7.5 27.2 6.8 6.3 24.5 11.7 6.5 10.1 8.5 22.5 21.5 26.3 18.1 7.8 19.4 35.1 8.8 13.7 1.6 10.4 44.4 12.2 23.5 14.3 8.7 16.5 18.2 10.6 9.5 10.2 3.0 5.8 11.4 20.2 39.1 9.6 7.1 50.0 11.8 77.9 35.3 8.8 47.0 28.6 21.9 25.5 6.5 11.3 19.5 30.2 17.1 29.8 12.9 3.5 26.5 33.4 11.8 13.8 43.3 28.5 23.2 20.7 17.3 19.0 15.2 32.8 33.2 5.1 30.8 17.5 21.9 28.2 19.3 18.6 19.8 22.6 32.4 15.2 16.3 17.9 25.4 15.9 27.1 22.7 18.4 22.8 10.7 10.9 10.4 14.3 10.4 11.2 13.5 11.4 10.1 10.6 11.2 10.5 10.1 12.8 6.4 19.9 11.1 7.8 17.5 22.6 16.5 12.8 11.3 8.9 6.8 15.7 14.8 9.2 12.5 21.1 15.0 14.8 15.6 10.6 20.8 7.1 12.3 13.0 11.4 10.3 14.2 13.8 12.9 12.8 26.0 7.5 14.0 34.9 15.4 15.3 34.2 3.3 16.2 14.8 8.2 13.1 6.7 9.4 22.7 13.3 7.2 12.2 17.6 14.4 9.2 13.6 11.3 12.0 12.1 22.2 14.4 9.1 15.0 16.6 8.1 11.9 6.6 9.4 10.7 28.8 39.5 8.0 6.8 14.6 11.9 31.7 17.9 7.6 BST2 "CD317, tetherin" ENSG00000130303 "Bone marrow stromal cell antigen 2" Q10589 19 17402939-17405630 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, B-cell activation, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 694.2" "Cell type enhanced" "Detected in many" "Adipocytes: 1193.2;Hepatic stellate cells: 455.8;Theca cells: 490.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 615.0;Karpas-707: 603.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA017060, HPA073472" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 260000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles" "HPA017060: AB_1845467, HPA073472: " "prognostic favorable (6.69e-4)" "unprognostic (1.75e-1)" "unprognostic (8.42e-3)" "unprognostic (8.93e-3)" "unprognostic (4.87e-2)" "unprognostic (2.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.07e-1)" "unprognostic (3.25e-1)" "unprognostic (6.46e-2)" "unprognostic (6.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.56e-9)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" 226.0 509.8 86.7 95.6 87.6 103.7 152.9 84.0 125.7 93.4 81.7 94.1 47.4 58.7 59.5 40.3 248.0 109.4 111.2 85.1 84.5 160.1 227.8 141.4 128.0 101.5 85.9 694.2 26.3 13.8 56.8 203.0 88.4 88.6 33.3 2.0 77.7 105.2 46.1 24.8 109.1 76.0 97.0 238.5 84.1 35.4 91.1 123.5 54.0 50.8 65.8 82.9 88.6 90.8 327.0 0.5 0.9 145.6 0.0 1.0 49.6 1.3 24.9 459.5 615.0 150.5 286.1 252.2 338.2 197.6 14.6 1.3 212.9 23.9 14.3 279.1 1.8 3.6 525.7 149.8 256.7 120.1 304.7 1.3 0.0 153.0 0.1 4.4 119.0 6.0 146.3 603.4 0.0 89.5 57.7 208.6 158.0 0.1 407.9 105.5 0.8 530.7 110.1 1.5 0.6 1.4 325.5 12.3 410.5 12.3 243.1 166.3 1.5 1.9 11.4 0.5 3.3 308.3 439.3 168.0 1.3 470.8 2.2 229.7 345.3 125.3 171.4 385.5 163.0 115.2 143.2 160.0 283.8 146.5 114.8 132.6 113.3 353.2 359.3 421.7 143.3 367.9 86.7 87.6 84.0 125.7 85.1 84.5 101.5 85.9 88.4 97.0 91.1 90.8 1193.2 57.7 13.6 4.9 90.7 33.1 19.6 255.7 48.9 0.2 86.2 168.5 7.0 50.1 68.5 49.7 0.0 7.8 184.2 1.5 37.2 18.7 10.7 27.8 11.2 420.2 1.2 74.0 0.0 1.2 61.5 152.4 14.8 50.1 227.8 260.9 455.8 211.1 388.9 0.0 0.0 2.8 28.5 189.4 187.6 12.0 346.7 220.4 74.7 32.8 214.5 1.3 211.2 0.5 0.3 3.3 4.8 419.4 192.8 10.3 3.7 1.3 27.4 2.1 164.3 30.7 146.3 1.3 1.2 15.5 26.1 13.1 135.8 490.6 5.0 28.6 BTBD6 BDPL ENSG00000184887 "BTB domain containing 6" Q96KE9 14 105248490-105251093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031355 Approved Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA031355: AB_10611812" "prognostic favorable (1.11e-4)" "unprognostic (2.01e-2)" "unprognostic (2.65e-1)" "unprognostic (1.97e-2)" "unprognostic (2.69e-1)" "unprognostic (2.58e-1)" "unprognostic (2.23e-2)" "unprognostic (4.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-1)" "prognostic favorable (2.25e-4)" "unprognostic (8.48e-3)" "prognostic favorable (6.51e-5)" "unprognostic (6.55e-2)" "unprognostic (3.22e-1)" "unprognostic (6.86e-2)" "unprognostic (9.85e-2)" 69.4 26.3 52.1 20.4 52.6 28.2 56.6 48.3 60.3 32.6 48.1 43.8 28.8 31.4 28.1 50.9 30.8 20.5 52.1 54.2 51.7 34.5 44.2 34.7 22.0 49.7 51.0 36.7 13.2 12.6 39.9 15.6 49.9 43.6 23.1 14.6 42.8 23.5 169.4 48.5 39.5 18.8 48.4 31.4 46.9 79.3 52.1 18.4 30.4 144.6 19.0 38.9 37.7 51.3 50.8 39.8 21.4 56.8 66.8 46.2 0.1 45.6 41.1 69.2 46.9 31.3 45.2 15.9 27.4 67.0 14.5 66.2 41.3 43.9 34.0 41.2 33.5 11.7 58.6 0.0 45.6 35.8 21.7 48.3 59.6 31.9 25.7 26.9 55.9 52.2 0.0 0.3 37.3 71.8 37.8 14.5 9.1 47.6 67.6 40.3 0.1 14.9 26.5 55.0 34.8 14.8 42.9 34.3 35.0 14.7 69.9 45.3 37.9 55.5 1.5 82.1 57.8 10.2 14.7 7.8 57.2 16.4 44.1 0.5 0.6 2.9 2.3 1.0 2.2 1.3 2.4 2.3 0.7 0.7 1.8 1.2 0.3 0.4 0.8 1.5 5.3 0.6 52.1 52.6 48.3 60.3 54.2 51.7 49.7 51.0 49.9 48.4 52.1 51.3 31.5 25.6 24.3 3.9 5.4 11.7 25.7 6.5 6.2 23.1 24.0 23.4 22.0 14.3 15.3 11.0 6.2 2.8 25.3 31.0 21.5 5.7 15.0 25.6 19.5 17.8 20.4 5.2 12.4 0.0 3.8 17.3 10.2 34.9 24.7 22.2 17.9 15.4 7.8 20.2 12.5 31.2 10.2 9.8 10.0 35.2 9.3 10.3 12.4 8.4 3.6 19.1 5.2 5.0 3.7 1.0 11.6 7.5 7.6 16.3 20.5 11.6 15.5 18.8 13.1 15.7 13.0 7.8 8.3 9.6 12.6 2.2 16.4 15.2 21.9 19.5 BTD ENSG00000169814 Biotinidase P43251 3 15601341-15722311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 95.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" NA NA 2800000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA052275: AB_2681782" "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" 25.3 16.7 10.7 8.0 12.7 13.1 16.4 20.2 12.6 13.7 11.0 15.9 46.1 13.2 62.4 9.9 18.3 19.9 10.2 11.5 10.3 37.6 95.9 15.9 9.6 12.0 10.0 25.3 44.1 27.7 5.9 17.0 12.6 19.5 17.0 35.2 16.0 21.1 7.8 9.5 30.7 14.1 10.3 11.3 24.4 18.2 9.9 10.6 26.8 11.4 10.4 14.3 7.5 19.1 9.2 22.0 7.8 7.3 51.7 15.3 39.6 15.4 18.4 16.2 28.3 10.1 21.5 4.1 16.3 31.6 7.1 9.7 5.3 16.7 18.7 7.6 11.7 12.9 28.8 24.8 12.7 8.8 14.7 18.3 16.9 42.9 5.1 39.7 30.5 5.9 8.7 32.3 44.7 11.1 4.5 8.2 8.5 16.9 13.0 5.9 18.4 27.9 16.5 17.7 5.3 11.8 17.9 5.2 24.4 15.1 19.9 11.3 24.3 20.5 13.6 19.1 10.1 8.9 11.4 4.1 21.4 7.7 14.4 74.1 20.7 44.9 22.9 19.6 21.0 14.7 23.3 19.2 21.4 13.1 19.7 15.4 19.8 15.0 15.8 24.9 28.8 16.5 10.7 12.7 20.2 12.6 11.5 10.3 12.0 10.0 12.6 10.3 9.9 19.1 14.9 6.4 11.0 11.8 11.7 5.9 12.4 25.0 6.2 13.5 9.1 7.9 6.0 45.8 16.7 18.4 18.8 25.3 19.7 9.9 5.9 21.1 31.0 9.5 6.0 9.1 7.2 4.0 6.6 28.5 22.4 14.5 9.7 5.7 5.1 8.9 20.3 63.3 14.9 5.0 12.2 8.5 16.2 8.2 5.9 17.9 32.3 9.2 10.6 5.6 8.7 19.2 6.2 27.2 23.9 12.0 17.9 18.0 16.6 6.3 52.1 32.0 19.8 54.1 13.1 8.5 8.6 45.3 7.5 7.7 5.5 23.1 13.6 17.4 8.9 9.5 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 BTLA "BTLA1, CD272" ENSG00000186265 "B and T lymphocyte associated" Q7Z6A9 3 112463966-112499472 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 28.6" "Cell type enriched" "Detected in some" 4 "B-cells: 66.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 65.0;naive B-cell: 96.5;plasmacytoid DC: 24.9" "Group enriched" "Detected in many" 4 "B-cells: 96.5;dendritic cells: 24.9" "Cell line enhanced" "Detected in single" "U-698: 2.0" "Not detected" "Not detected" "HPA047211, HPA062029" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA047211: AB_2679983, HPA062029: AB_2684665" "unprognostic (1.13e-3)" "unprognostic (2.13e-3)" "unprognostic (5.79e-4)" "unprognostic (1.01e-4)" "unprognostic (7.08e-2)" "unprognostic (7.74e-6)" "unprognostic (6.20e-3)" "unprognostic (7.59e-3)" "unprognostic (5.98e-2)" "unprognostic (1.53e-5)" "unprognostic (2.33e-2)" "unprognostic (1.23e-1)" "unprognostic (1.57e-5)" "unprognostic (2.57e-1)" "unprognostic (2.46e-2)" "unprognostic (1.65e-1)" "unprognostic (1.42e-2)" 0.4 0.3 0.0 11.2 0.0 2.1 1.9 0.1 0.4 0.5 0.0 1.7 1.6 0.3 0.1 0.6 0.3 1.1 0.2 0.0 0.0 0.3 0.6 0.9 26.4 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.1 0.4 1.6 0.2 1.3 0.1 0.1 0.1 3.1 0.4 0.0 10.8 3.0 0.1 0.0 7.7 0.3 0.1 28.6 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 0.1 0.0 11.2 0.0 8.3 65.0 13.6 6.5 4.6 96.5 12.7 12.6 0.5 0.3 0.1 24.9 3.4 6.5 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 66.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.3 0.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.5 1.3 0.0 0.4 0.2 0.1 0.0 0.4 0.0 0.0 1.3 4.7 3.6 0.0 1.6 7.2 0.0 1.9 0.0 0.0 1.0 0.3 0.0 0.0 0.0 15.9 0.0 0.0 0.2 0.7 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.3 0.1 8.6 0.0 0.0 0.1 BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 59.1;NK-cells: 73.2;Plasma cells: 47.6;T-cells: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012565: AB_1845494" "unprognostic (2.82e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-3)" "unprognostic (4.72e-3)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.81e-2)" "unprognostic (8.60e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "prognostic unfavorable (4.15e-5)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "unprognostic (3.26e-2)" "prognostic favorable (4.81e-4)" 19.2 20.7 10.2 44.8 11.1 29.6 20.1 9.8 10.5 21.2 10.3 24.8 28.5 28.0 16.0 11.9 22.5 30.5 12.1 9.1 12.1 12.8 18.9 41.4 63.4 16.4 10.9 35.1 13.1 13.1 13.7 19.2 12.5 16.5 28.8 3.6 23.9 13.5 12.8 24.9 35.1 21.3 12.2 84.0 31.3 5.0 11.4 33.1 11.5 14.5 52.6 20.0 17.4 12.0 7.4 6.2 9.3 9.5 25.9 27.5 1.2 6.2 24.1 13.5 39.4 0.3 16.7 19.7 20.4 11.2 20.9 5.1 3.0 9.7 8.2 19.5 6.4 10.4 8.5 4.7 11.8 9.5 9.3 15.0 5.6 11.8 5.4 20.4 19.3 31.0 2.5 25.3 5.5 0.6 17.6 6.6 1.0 3.3 2.1 24.2 4.0 45.2 8.3 9.4 4.9 9.8 3.4 7.1 13.5 1.4 6.5 4.0 4.8 10.3 2.6 3.1 5.9 41.8 45.9 7.3 15.6 21.4 8.4 53.8 11.1 28.8 44.7 11.7 40.4 18.8 27.8 42.3 9.1 10.5 24.1 32.0 23.9 40.5 12.9 4.3 36.0 28.0 10.2 11.1 9.8 10.5 9.1 12.1 16.4 10.9 12.5 12.2 11.4 12.0 24.8 16.0 6.5 0.0 27.1 4.2 3.9 3.5 2.2 4.3 8.6 8.1 4.2 11.5 8.5 5.5 0.0 5.5 59.1 8.2 0.0 7.4 0.1 5.5 10.4 18.0 4.8 13.3 0.0 3.2 4.3 9.9 9.2 10.3 25.9 14.0 11.7 3.9 7.2 0.0 0.0 17.3 2.0 19.2 6.1 0.8 3.7 15.4 1.8 0.0 13.7 1.9 73.2 0.0 0.0 2.2 6.3 2.6 47.6 5.4 15.9 1.3 6.7 0.4 0.0 6.7 5.5 0.0 0.1 3.6 3.3 1.5 50.1 8.4 7.4 5.0 BTN3A2 BTN3.2 ENSG00000186470 "Butyrophilin subfamily 3 member A2" P78410 6 26365159-26378320 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 88.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.2;NK-cells: 239.9;T-cells: 108.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 87.5" CAB019392 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB019392: " "unprognostic (3.77e-2)" "unprognostic (1.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.86e-2)" "unprognostic (3.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.40e-1)" "unprognostic (3.89e-1)" "unprognostic (4.04e-2)" "unprognostic (1.30e-3)" "unprognostic (1.12e-1)" "unprognostic (8.45e-2)" "prognostic unfavorable (4.24e-4)" "unprognostic (5.13e-2)" "unprognostic (4.45e-2)" "unprognostic (4.42e-2)" "unprognostic (1.48e-3)" 19.4 27.3 8.6 41.9 8.5 9.5 18.4 7.6 8.7 18.1 7.9 29.0 29.3 21.7 21.0 13.5 22.0 25.0 13.8 7.3 9.3 15.8 23.6 41.0 45.5 13.1 8.9 29.6 10.4 10.4 12.7 18.4 9.9 14.9 31.7 2.4 19.4 14.9 8.4 21.7 32.9 20.8 10.5 88.3 32.6 7.1 8.7 38.3 14.4 10.7 44.6 22.9 17.0 10.9 10.6 4.8 6.4 6.7 37.4 42.9 2.2 10.2 48.2 18.8 52.6 2.7 34.4 30.6 35.5 16.2 27.5 9.2 9.4 18.6 17.1 18.5 13.2 33.1 19.1 20.1 20.7 18.9 26.5 27.0 7.5 17.9 8.5 43.9 36.0 54.0 8.5 41.1 13.1 1.4 16.2 30.4 0.4 8.6 3.6 24.3 11.5 87.5 17.1 6.5 4.2 12.8 8.2 7.5 25.7 1.9 7.5 14.0 22.4 17.7 4.0 7.6 11.3 86.1 79.7 17.7 32.2 33.2 17.5 67.7 26.7 57.6 128.3 35.9 96.1 64.5 81.3 113.8 19.2 53.4 81.8 100.1 40.0 98.8 47.5 13.5 111.2 71.3 8.6 8.5 7.6 8.7 7.3 9.3 13.1 8.9 9.9 10.5 8.7 10.9 62.5 32.1 22.2 2.3 61.3 10.3 12.2 8.6 13.1 0.7 16.0 9.9 7.5 17.2 7.4 12.9 0.0 14.3 117.2 21.8 1.9 25.6 0.2 23.6 21.3 46.0 10.1 25.2 1.0 13.7 17.3 20.2 15.8 14.7 47.4 23.4 40.0 9.8 17.8 0.0 2.5 37.9 10.2 54.0 10.0 1.9 11.1 37.1 3.6 20.6 52.7 7.0 239.9 7.1 1.7 10.6 16.9 10.5 76.6 13.2 50.5 3.8 11.8 1.4 13.1 15.7 10.2 1.5 0.2 8.3 13.4 3.3 108.0 51.0 25.5 16.8 BTN3A3 "BTF3, BTN3.3" ENSG00000111801 "Butyrophilin subfamily 3 member A3" O00478 6 26440472-26453415 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 26.9;NK-cells: 33.0;Plasma cells: 30.5;T-cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 62.8;BJ hTERT+ SV40 Large T+ RasG12V: 43.8" "HPA007904, HPA011871" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "HPA007904: AB_1078307, HPA011871: AB_1845496" "unprognostic (1.18e-2)" "unprognostic (6.54e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-2)" "unprognostic (2.30e-2)" "unprognostic (8.60e-2)" "unprognostic (5.13e-3)" "unprognostic (8.08e-2)" "unprognostic (7.88e-2)" "prognostic favorable (1.80e-4)" "unprognostic (4.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (3.49e-2)" "unprognostic (2.14e-2)" "unprognostic (5.26e-2)" "unprognostic (4.54e-3)" 14.9 19.6 7.4 20.0 7.0 5.5 12.0 6.5 7.9 16.6 8.0 15.0 17.5 16.7 18.7 8.3 20.3 20.3 9.0 7.2 9.0 8.9 20.6 33.7 29.2 10.0 7.2 19.5 4.8 5.0 12.2 10.2 7.6 9.4 14.6 1.8 12.3 11.2 5.8 11.6 16.7 17.1 9.0 47.2 16.3 3.3 7.5 21.5 9.2 14.4 22.8 16.7 9.5 8.2 4.1 1.8 1.8 1.6 33.2 62.8 0.5 5.4 29.7 12.0 43.8 0.0 12.3 25.0 24.5 9.0 11.1 2.9 2.6 9.7 5.8 21.4 4.2 11.5 11.8 1.3 24.2 6.4 2.1 33.4 3.8 10.5 3.9 19.3 24.1 9.4 0.5 3.7 6.7 0.0 16.7 5.3 0.1 0.0 2.9 16.7 3.3 24.9 9.4 3.3 2.2 3.9 3.3 3.1 6.2 0.4 0.8 3.5 15.0 5.8 1.3 6.5 3.8 4.1 1.0 2.5 15.4 12.0 6.2 49.0 15.7 13.4 54.7 23.2 43.7 19.3 37.6 55.5 12.4 14.0 36.3 49.0 11.6 45.9 24.6 6.4 46.2 33.3 7.4 7.0 6.5 7.9 7.2 9.0 10.0 7.2 7.6 9.0 7.5 8.2 20.3 9.6 7.7 0.3 15.9 1.8 1.9 2.8 8.0 0.2 3.6 2.8 4.9 0.0 5.2 0.0 0.0 2.5 26.9 6.4 1.9 5.3 4.6 4.2 9.4 22.1 1.2 9.9 1.4 2.3 1.6 11.1 7.1 4.3 3.8 8.7 15.7 4.0 4.3 0.0 2.1 8.9 0.0 20.8 4.0 18.0 4.1 12.4 3.6 2.8 12.6 2.3 33.0 1.5 0.4 2.4 3.9 2.2 30.5 2.0 12.8 1.1 3.3 0.0 6.6 4.9 4.0 0.4 0.3 3.1 2.0 0.5 27.1 12.3 6.2 1.9 C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 50.4;heart muscle: 20.0;lymphoid tissue: 14.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 68.1;dendritic cells: 29.4;Macrophages: 20.3;monocytes: 28.4;NK-cells: 47.4;T-cells: 16.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 51.7;HL-60: 19.7;NB-4: 18.4;THP-1: 12.7;U-937: 22.2" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA037607: AB_10672909" "unprognostic (5.25e-3)" "unprognostic (2.65e-4)" "unprognostic (1.35e-1)" "unprognostic (4.61e-3)" "unprognostic (4.32e-2)" "unprognostic (3.58e-4)" "unprognostic (8.98e-4)" "unprognostic (2.37e-3)" "unprognostic (1.87e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.84e-4)" "unprognostic (8.50e-2)" "unprognostic (9.54e-2)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" 1.4 0.6 0.3 7.1 0.4 50.4 0.6 0.4 0.4 1.6 0.2 0.9 0.6 0.6 0.3 0.6 0.7 2.1 20.0 0.3 0.3 0.7 1.3 4.7 14.0 1.1 0.5 0.2 0.4 0.1 0.3 0.6 0.8 0.6 1.3 0.0 1.5 0.4 1.0 1.3 3.5 1.0 0.6 14.9 2.6 0.3 0.4 3.6 0.9 0.2 7.3 1.1 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 51.7 0.1 0.1 0.5 19.7 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.4 22.2 0.0 80.3 14.9 45.8 23.8 31.4 16.1 4.7 7.8 18.8 17.1 5.8 11.6 16.3 12.6 23.9 58.4 1.7 6.1 16.5 0.3 0.4 0.4 0.4 0.3 0.3 1.1 0.5 0.8 0.6 0.4 1.0 0.2 0.0 4.2 0.0 6.9 0.4 0.0 0.0 0.0 0.0 0.1 0.3 68.1 2.8 0.0 0.0 0.0 0.1 29.4 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 13.9 0.0 0.0 0.2 1.7 0.5 0.0 15.8 0.0 2.5 0.0 3.7 0.0 0.0 0.0 0.0 12.5 15.5 0.0 0.0 20.3 1.8 0.0 28.4 0.0 47.4 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.4 0.0 16.0 0.0 0.0 0.0 C11orf86 FLJ22675 ENSG00000173237 "Chromosome 11 open reading frame 86" A6NJI1 11 66975277-66977004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 68.0" "Group enriched" "Detected in some" 20 "Distal enterocytes: 212.2;Paneth cells: 132.8;Proximal enterocytes: 506.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 7.2;SiHa: 24.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA039348 Uncertain NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA039348: AB_10673421" "unprognostic (1.54e-2)" "unprognostic (7.67e-3)" "unprognostic (3.02e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "prognostic unfavorable (8.97e-4)" "unprognostic (4.17e-1)" "prognostic unfavorable (6.97e-5)" "prognostic unfavorable (1.02e-5)" "unprognostic (7.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.69e-2)" "unprognostic (3.58e-3)" 0.1 15.4 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.0 0.1 10.4 68.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.0 64.2 0.7 0.1 0.0 2.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.9 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 212.2 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 132.8 0.0 0.0 0.0 506.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 8.4 0.2 C12orf43 "Custos, FLJ12448" ENSG00000157895 "Chromosome 12 open reading frame 43" Q96C57 12 121000486-121016502 "Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046148, HPA061739" Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Cluster 30: Non-specific - Translation" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli "Golgi apparatus" "HPA046148: AB_10965169, HPA061739: AB_2684597" "unprognostic (1.51e-1)" "unprognostic (5.75e-2)" "unprognostic (3.44e-1)" "unprognostic (1.75e-2)" "unprognostic (2.43e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (6.44e-4)" "unprognostic (3.53e-1)" "unprognostic (5.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.95e-1)" "unprognostic (2.45e-3)" "unprognostic (9.70e-2)" "unprognostic (2.49e-1)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" 9.8 8.1 11.7 6.9 11.9 7.4 9.3 8.8 13.6 7.8 7.2 11.2 5.0 9.5 4.4 7.2 9.0 5.1 7.4 12.3 9.5 8.2 10.5 6.7 8.7 10.9 9.6 11.2 7.5 9.0 7.4 7.2 10.8 7.7 5.3 6.0 8.7 6.2 7.2 6.7 6.7 8.4 8.6 7.8 8.2 6.1 9.4 7.2 6.4 5.9 7.4 9.6 7.0 10.4 14.2 31.4 16.2 12.8 14.0 11.0 17.8 17.2 17.5 28.3 17.9 22.8 13.0 26.2 17.2 16.8 15.0 15.7 19.2 26.3 16.8 31.6 21.4 21.1 12.4 17.1 16.7 28.1 16.2 12.9 13.6 26.0 16.4 17.9 16.4 27.0 25.5 6.7 15.1 23.3 30.9 22.0 28.8 11.1 23.2 27.4 19.0 19.8 17.5 20.8 22.0 14.0 23.0 9.9 18.6 13.4 27.0 13.1 15.9 15.6 18.7 12.8 18.4 12.3 19.1 20.5 20.5 16.5 23.6 5.7 15.6 9.0 23.8 21.3 21.8 23.8 23.5 23.2 16.1 19.0 27.5 23.6 2.2 18.4 18.5 13.3 23.8 20.6 11.7 11.9 8.8 13.6 12.3 9.5 10.9 9.6 10.8 8.6 9.4 10.4 16.1 25.6 18.1 3.3 17.3 8.8 16.4 12.2 6.8 19.6 12.4 12.4 7.0 11.5 9.6 18.4 20.9 24.3 13.9 8.6 23.5 16.5 5.9 9.8 17.1 16.0 2.4 10.7 6.8 18.5 22.3 16.3 8.2 10.1 14.5 22.3 12.5 11.7 16.7 16.8 6.4 9.5 10.2 10.4 7.3 13.8 13.7 13.2 14.2 3.7 21.7 18.8 24.7 4.0 4.8 15.6 12.3 12.8 11.3 13.8 5.3 16.7 16.3 15.7 19.7 19.6 16.9 16.3 16.4 12.7 7.7 13.7 17.6 16.0 10.9 14.0 C12orf54 MGC35033 ENSG00000177627 "Chromosome 12 open reading frame 54" Q6X4T0 12 48482498-48496524 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 39 "testis: 40.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2541.6" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HBEC3-KT: 2.7" "Not detected" "Not detected" HPA073090 Approved "Intermediate filaments" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments" "HPA073090: " "unprognostic (2.59e-3)" "unprognostic (5.49e-2)" "unprognostic (7.94e-3)" "unprognostic (2.60e-2)" "unprognostic (2.48e-2)" "unprognostic (8.99e-2)" "unprognostic (5.96e-2)" "unprognostic (1.62e-1)" "unprognostic (8.01e-2)" "unprognostic (1.36e-4)" "unprognostic (2.37e-1)" "unprognostic (5.06e-3)" "unprognostic (7.53e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.92e-1)" 0.0 0.4 0.3 0.0 0.4 0.0 0.2 0.2 1.0 0.1 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.3 0.3 0.1 0.0 40.4 0.3 0.0 0.0 0.2 0.6 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.0 0.3 0.2 0.5 0.4 0.5 0.3 0.3 0.5 0.0 0.0 2.6 8.1 0.0 5.1 38.6 19.5 1.2 0.2 0.2 0.1 0.7 0.0 4.5 0.0 0.0 0.1 0.0 0.0 1.9 0.1 543.1 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.2 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 9.1 0.0 2.0 0.0 1.8 2541.6 10.8 1.4 0.0 2.8 0.0 0.3 0.0 4.5 2.5 0.0 0.0 13.2 0.0 6.4 0.0 1.9 1.9 0.2 6.6 4.3 1.0 11.5 6.5 5.9 2.3 0.0 0.5 0.4 0.0 10.8 C14orf132 C14orf88 ENSG00000227051 "Chromosome 14 open reading frame 132" Q9NPU4 14 96039362-96093971 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 74.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Bipolar cells: 57.8;Endometrial ciliated cells: 55.2;Horizontal cells: 63.9;Skeletal myocytes: 44.9" "Cancer enhanced" "Detected in many" "glioma: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 49.9;SCLC-21H: 52.5;SH-SY5Y: 52.0;U-87 MG: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.47e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" "unprognostic (4.42e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.51e-2)" "unprognostic (5.55e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-2)" "unprognostic (1.33e-5)" "prognostic unfavorable (4.95e-4)" 5.9 14.0 57.3 3.2 58.1 0.1 6.9 62.8 69.1 23.3 20.5 23.8 2.1 26.2 14.2 7.1 22.5 5.0 4.1 74.7 52.5 9.9 4.1 18.4 0.8 53.6 49.8 5.2 3.2 0.1 38.8 0.8 50.9 9.5 4.4 12.8 3.0 19.8 3.0 13.8 14.2 22.3 51.2 6.2 15.7 1.3 55.8 3.1 2.4 6.6 1.2 8.5 11.9 56.1 0.0 6.4 30.8 9.7 22.0 22.0 0.1 10.6 23.8 13.6 8.3 0.1 0.1 0.0 2.4 23.8 9.0 0.7 3.7 0.8 11.7 0.0 1.4 0.1 1.2 0.1 2.7 0.0 0.2 12.0 1.2 12.7 1.0 0.0 0.2 3.0 0.0 0.1 6.3 49.9 0.8 0.1 15.0 0.0 0.0 28.5 5.0 0.1 11.0 22.4 52.5 52.0 8.3 1.0 1.5 8.3 28.9 1.4 0.0 10.8 6.5 18.0 0.0 0.0 0.0 0.1 46.1 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.2 57.3 58.1 62.8 69.1 74.7 52.5 53.6 49.8 50.9 51.2 55.8 56.1 4.8 38.5 10.6 14.7 0.4 2.7 3.7 5.9 5.2 57.8 0.7 7.1 1.9 1.5 3.9 7.3 20.9 0.3 0.2 0.0 5.9 5.8 3.0 55.2 23.8 8.6 9.0 0.0 20.3 0.2 1.0 16.6 2.0 6.8 1.3 5.4 19.2 4.0 0.3 63.9 11.2 0.1 4.1 0.6 7.1 3.0 15.8 0.5 8.8 7.5 0.1 4.0 0.0 11.1 24.7 1.2 0.1 13.5 0.1 2.1 0.0 0.0 13.6 6.1 0.0 44.9 4.4 0.3 0.6 6.8 7.7 0.3 1.0 0.6 0.1 2.3 C14orf180 "C14orf77, NRAC" ENSG00000184601 "Chromosome 14 open reading frame 180" Q8N912 14 104579764-104590515 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.8;breast: 26.7;heart muscle: 109.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.7;Cardiomyocytes: 7.6;Fibroblasts: 2.0;Hepatic stellate cells: 3.3;Horizontal cells: 3.3;Smooth muscle cells: 1.4" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "ASC diff: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.48e-2)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (3.19e-3)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (9.80e-2)" 40.8 3.1 0.0 0.1 0.2 0.0 26.7 0.2 0.2 0.9 13.5 0.9 0.3 1.1 0.0 0.0 1.8 0.2 109.5 1.5 0.0 1.8 4.1 0.4 0.0 0.5 0.8 0.8 0.8 0.0 1.8 0.8 0.5 0.6 0.0 0.1 0.9 0.4 5.7 0.6 1.4 0.0 0.0 0.5 2.2 0.1 0.4 0.0 0.9 0.7 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 1.5 0.0 0.5 0.8 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 C19orf12 "DKFZP762D096, MGC10922, MPAN, NBIA4, SPG43" ENSG00000131943 "Chromosome 19 open reading frame 12" Q9NSK7 19 29698886-29715789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 118.9;tongue: 105.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046930 Approved Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA046930: AB_10962836" "unprognostic (1.76e-1)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.01e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.54e-1)" "unprognostic (9.94e-3)" "unprognostic (7.93e-3)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (3.22e-1)" "unprognostic (1.22e-3)" 118.9 25.3 22.1 14.4 25.8 4.4 40.8 16.6 24.8 13.8 12.6 16.8 19.5 14.3 9.0 13.2 12.8 12.9 30.9 23.9 22.7 20.8 69.3 11.3 21.2 20.5 20.3 14.7 17.1 15.4 14.5 13.2 21.7 14.1 9.3 8.5 18.1 12.4 62.2 14.7 17.6 13.4 16.8 16.0 12.9 7.3 23.1 14.1 10.7 105.5 13.6 15.2 11.7 19.9 19.9 39.4 18.4 23.2 45.0 27.5 28.8 23.1 22.7 22.5 29.2 19.1 8.1 16.1 24.1 29.1 20.4 8.5 15.7 9.5 15.1 42.8 28.3 18.0 13.5 33.2 25.1 14.0 22.8 31.8 20.2 13.7 10.9 18.0 20.1 9.8 14.0 20.3 23.7 13.8 9.9 10.1 11.1 17.3 9.9 19.2 19.1 12.3 17.2 20.1 11.3 23.8 13.9 17.8 37.0 18.8 7.6 15.4 20.9 47.4 37.0 19.5 21.2 28.4 27.1 12.0 28.3 8.4 20.3 1.1 2.3 1.4 16.0 2.5 9.4 4.6 9.1 11.6 2.2 3.6 9.2 11.5 2.8 7.1 2.7 5.0 11.9 8.0 22.1 25.8 16.6 24.8 23.9 22.7 20.5 20.3 21.7 16.8 23.1 19.9 9.6 12.8 13.7 9.4 13.7 12.7 11.1 8.2 14.8 15.8 13.2 9.4 30.1 2.8 7.3 9.2 6.2 29.2 21.7 9.2 15.6 17.1 1.8 8.5 16.0 10.4 3.6 9.5 19.5 23.1 25.5 20.0 8.2 8.8 16.5 16.2 14.6 62.4 15.6 5.0 18.3 7.5 8.2 12.5 9.9 1.8 28.9 8.7 10.6 8.4 20.1 15.8 41.2 12.1 17.4 20.0 11.0 29.3 20.7 12.8 24.0 37.5 6.6 9.6 6.6 24.6 13.3 4.6 5.3 10.1 7.7 21.9 21.6 23.8 8.2 7.8 C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "granulocytes: 182.3;Hofbauer cells: 195.3;Kupffer cells: 797.4;Langerhans cells: 226.7;Macrophages: 413.5;monocytes: 278.6;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "HDLM-2: 141.3;HL-60: 70.4;NB-4: 40.3;THP-1: 55.2;U-937: 117.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" 45.4 23.6 16.3 70.8 16.2 115.0 22.3 17.2 29.0 13.2 19.6 15.8 7.3 11.5 6.3 9.8 22.5 31.2 18.1 16.3 18.4 12.5 41.9 85.7 70.4 20.6 17.3 9.4 9.4 4.8 9.1 15.2 19.7 11.7 17.9 9.5 11.2 6.6 10.1 7.8 21.2 37.6 16.7 134.5 12.5 7.6 23.3 27.7 10.0 7.4 55.9 25.1 10.8 21.4 0.3 0.1 0.5 1.1 0.4 0.6 0.6 0.9 0.1 0.3 0.3 0.2 0.4 0.5 0.5 0.2 0.1 0.2 0.8 0.5 0.6 141.3 0.4 0.4 0.5 0.0 0.4 70.4 11.1 0.0 2.6 0.8 0.9 1.0 2.0 0.7 0.5 0.4 0.5 0.5 0.6 40.3 0.2 0.7 0.8 0.1 0.7 0.1 0.3 0.1 0.5 0.2 0.5 0.6 0.8 0.6 0.3 55.2 0.0 0.8 1.0 0.7 0.6 0.6 0.1 0.6 0.3 117.9 1.2 1114.1 1026.8 1294.8 166.6 1529.2 47.6 231.0 206.5 97.3 1021.6 296.4 318.0 193.6 143.3 536.7 1173.4 302.8 66.7 1189.5 16.3 16.2 17.2 29.0 16.3 18.4 20.6 17.3 19.7 16.7 23.3 21.4 4.4 22.4 43.9 8.1 84.1 7.9 0.7 0.4 0.6 4.0 2.2 5.2 3.8 10.0 4.5 7.3 2.1 1.0 103.4 0.6 0.0 0.2 36.7 0.8 0.9 8.1 1.8 23.5 9.2 0.2 2.0 3.2 0.5 1.0 182.3 0.9 15.7 8.9 195.3 0.0 13.0 0.0 0.0 797.4 226.7 90.7 2.8 413.5 12.4 12.2 278.6 0.2 355.3 6.0 7.7 0.2 0.0 0.7 4.2 0.8 0.9 1.0 0.9 4.2 32.9 2.4 2.9 2.4 2.0 0.2 6.5 1.6 59.8 0.3 0.7 0.3 C1orf210 "MGC52423, TEMP" ENSG00000253313 "Chromosome 1 open reading frame 210" Q8IVY1 1 43281877-43285617 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.9;Paneth cells: 100.8;Proximal enterocytes: 128.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 14 "basophil: 2.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.2" "Cell line enhanced" "Detected in some" "A-431: 12.1;BEWO: 13.0;CACO-2: 12.6;CAPAN-2: 39.8;OE19: 33.1;SK-BR-3: 13.8;T-47d: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013788 Uncertain Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "HPA013788: AB_1845637" "unprognostic (1.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.54e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (0.00e+0)" "unprognostic (7.57e-3)" "unprognostic (3.94e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-2)" 0.2 0.1 0.3 2.9 0.3 0.2 14.5 0.7 0.5 8.2 0.3 32.4 43.9 1.3 13.0 17.0 6.1 9.9 0.1 0.3 0.2 21.8 6.2 9.0 0.1 0.3 0.4 0.1 22.8 10.3 8.4 1.6 0.4 8.1 30.2 0.5 19.5 3.8 0.0 16.2 38.7 1.2 0.2 0.1 29.1 0.3 0.3 1.0 16.9 0.0 2.3 3.2 8.1 0.8 12.1 0.0 0.0 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 12.6 39.8 0.0 0.3 0.0 0.0 9.0 0.0 5.6 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.0 0.0 0.2 0.1 33.1 0.0 0.1 0.1 0.4 1.0 7.8 4.6 0.3 0.1 13.8 0.0 2.1 15.2 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.7 0.5 0.3 0.2 0.3 0.4 0.4 0.2 0.3 0.8 0.1 22.4 16.1 0.3 0.6 1.1 6.2 11.5 2.8 0.0 22.4 12.8 0.0 28.6 13.8 22.0 0.0 12.9 0.0 125.9 29.4 21.3 0.1 8.5 1.4 0.2 33.6 0.0 0.0 33.7 3.9 0.2 25.5 14.2 0.0 0.0 0.0 1.2 0.7 0.0 0.0 42.4 8.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.3 100.8 0.0 0.0 6.6 128.1 39.6 7.3 0.0 0.0 0.0 0.7 0.3 0.0 8.9 2.6 4.7 0.3 0.0 37.0 8.8 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QTNF1 "CTRP1, FLJ90694, GIP, ZSIG37" ENSG00000173918 "C1q and TNF related 1" Q9BXJ1 17 79022814-79049788 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 214.2;heart muscle: 319.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 120.0;Sertoli cells: 105.2;Smooth muscle cells: 105.8;Syncytiotrophoblasts: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 313.5;BJ hTERT+: 72.9;HHSteC: 112.3;HSkMC: 61.3;U-87 MG: 66.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025429, HPA051101" Uncertain Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 314000000 40000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB025429: , HPA051101: AB_2681343" "unprognostic (2.58e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (1.20e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" "unprognostic (7.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-2)" "unprognostic (7.48e-2)" "unprognostic (9.81e-3)" "unprognostic (5.83e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (1.95e-2)" 214.2 75.3 9.5 14.8 15.2 0.5 156.0 16.1 13.3 50.2 45.3 38.3 4.6 45.1 6.5 18.9 63.5 24.3 319.1 9.1 18.2 25.3 45.7 44.4 14.0 18.3 25.4 70.5 14.9 13.5 17.5 42.2 18.0 57.1 6.3 0.9 34.9 44.0 27.0 38.6 29.3 13.3 14.1 35.7 25.0 5.4 21.9 5.1 115.0 21.3 6.6 34.7 42.3 13.2 0.1 32.3 0.3 0.1 313.5 27.1 0.2 13.6 72.9 7.0 11.9 2.7 14.0 0.1 1.5 5.1 18.1 0.7 1.0 0.5 5.0 0.1 3.5 0.2 11.7 1.5 112.3 0.1 0.2 61.3 0.2 14.5 0.8 9.3 8.8 1.6 0.1 0.3 1.6 0.1 0.3 0.2 3.0 3.7 27.9 0.1 22.3 0.4 0.0 0.4 1.3 5.3 9.2 1.8 32.7 1.2 0.0 0.0 1.4 32.6 0.8 4.0 4.8 0.3 0.1 0.1 66.2 0.2 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.5 15.2 16.1 13.3 9.1 18.2 18.3 25.4 18.0 14.1 21.9 13.2 36.1 0.0 0.6 4.9 0.4 6.5 0.7 12.3 0.6 0.1 9.2 1.8 10.8 5.7 0.5 1.8 0.0 21.5 0.4 3.2 0.0 19.5 0.1 0.6 17.9 38.3 4.8 2.7 0.2 5.9 1.5 23.6 2.6 0.6 0.0 25.3 120.0 1.9 2.6 0.0 0.9 6.3 2.0 7.5 11.3 0.7 10.5 1.1 3.6 5.6 10.9 0.5 0.0 0.5 0.3 3.7 3.1 3.4 0.1 1.8 0.9 0.2 0.3 0.5 105.2 12.7 105.8 0.0 0.7 0.4 4.5 47.3 0.8 18.1 5.2 0.6 C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 442.3;Fibroblasts: 684.4;Hepatocytes: 1444.2;Leydig cells: 1142.6;Peritubular cells: 388.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1089.8;ASC TERT1: 546.0;BJ hTERT+: 461.9;BJ hTERT+ SV40 Large T+ RasG12V: 303.4;HSkMC: 672.1" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 540.6 203.6 15.8 122.4 15.9 1.1 400.6 15.9 23.3 470.5 21.7 277.3 38.3 353.8 80.8 119.0 526.3 279.1 458.7 15.4 19.6 148.9 1425.6 340.3 72.4 23.4 19.9 644.3 88.0 11.0 63.9 52.4 18.4 205.2 100.9 5.8 158.3 87.0 69.4 177.7 228.1 157.7 18.1 192.1 242.7 46.7 18.1 34.7 223.4 74.2 75.3 468.4 394.3 18.0 1.2 8.9 0.9 9.1 1089.8 546.0 0.4 108.9 461.9 143.0 303.4 1.4 2.4 0.5 4.5 108.8 11.8 2.3 11.8 5.5 18.3 18.3 1.1 0.5 4.1 3.6 226.5 0.8 2.3 672.1 3.2 74.7 4.7 121.0 2.9 0.5 0.3 20.5 21.2 0.1 8.0 0.8 3.1 0.1 0.9 8.6 3.8 0.8 0.9 5.5 0.4 2.3 95.1 3.7 2.8 1.3 0.2 0.2 0.4 38.3 6.3 152.1 0.8 1.1 3.0 0.2 53.1 1.0 5.4 0.0 0.0 0.6 0.3 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.6 0.6 0.5 0.8 0.0 0.0 0.3 0.1 15.8 15.9 15.9 23.3 15.4 19.6 23.4 19.9 18.4 18.1 18.1 18.0 45.4 22.4 90.5 3.6 7.1 54.7 58.8 76.6 33.6 0.3 5.9 30.9 20.8 183.0 22.9 18.4 2.1 4.1 1.8 0.7 3.9 280.8 4.6 13.3 442.3 45.4 0.0 40.6 0.9 44.5 3.7 684.4 16.3 11.6 10.1 24.9 114.9 1444.2 11.2 0.0 0.3 0.7 0.0 40.9 66.9 29.2 1142.6 7.0 53.4 13.1 1.6 16.0 0.0 2.5 0.1 51.1 1.3 388.1 6.2 17.7 0.3 6.1 5.3 1.4 170.9 87.5 140.4 6.8 6.7 5.6 40.1 5.2 11.5 15.2 0.7 11.2 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C20orf27 FLJ20550 ENSG00000101220 "Chromosome 20 open reading frame 27" Q9GZN8 20 3753508-3767781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 178.7;Hofbauer cells: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 144.6;intermediate monocyte: 249.1;myeloid DC: 199.4;non-classical monocyte: 235.3" "Group enriched" "Detected in all" 5 "dendritic cells: 199.4;monocytes: 249.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047483 Approved Approved Nucleoplasm,Cytosol NA NA 140000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA047483: AB_2680064" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.21e-3)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (1.69e-5)" "unprognostic (8.36e-2)" "unprognostic (2.07e-1)" "unprognostic (4.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (1.80e-1)" "unprognostic (2.16e-1)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" 55.8 24.0 48.8 20.4 125.4 103.6 45.2 44.7 70.9 39.5 33.7 117.3 17.0 42.5 8.7 29.6 51.8 25.5 27.9 45.6 63.3 25.7 24.7 20.8 24.5 52.9 59.3 66.3 23.6 9.4 23.3 8.9 67.5 24.2 7.8 4.9 15.7 10.9 22.4 26.9 33.9 14.1 43.8 45.5 86.8 22.7 59.5 11.0 23.4 11.5 9.8 73.9 26.3 40.7 172.9 177.7 24.4 106.1 49.5 28.1 42.7 45.5 25.1 70.4 50.3 120.5 61.6 111.1 41.4 48.2 94.7 140.9 65.7 101.9 24.9 26.1 138.3 63.2 35.9 212.6 36.2 88.2 24.7 41.0 41.8 93.3 46.1 24.2 48.2 72.9 114.6 59.8 37.3 240.2 107.6 186.3 114.9 107.0 248.4 86.6 67.9 123.7 43.9 62.0 121.8 56.6 41.2 155.3 85.1 10.4 36.9 96.8 35.9 104.8 73.8 171.6 129.6 50.5 93.2 80.7 31.5 161.2 53.9 1.3 144.6 2.3 28.7 249.1 42.1 38.7 33.6 38.6 199.4 36.2 37.6 37.5 5.4 32.5 235.3 38.7 34.2 87.4 48.8 125.4 44.7 70.9 45.6 63.3 52.9 59.3 67.5 43.8 59.5 40.7 54.0 0.0 3.3 3.3 26.5 24.2 23.0 26.8 35.3 9.7 28.2 45.7 3.7 8.6 7.4 11.0 2.1 17.5 15.8 10.2 29.4 32.6 21.8 13.8 178.7 28.7 15.7 99.1 6.0 30.0 49.2 27.1 14.3 7.5 22.9 45.0 19.6 17.9 142.9 1.7 9.5 15.9 16.2 119.0 53.1 15.3 32.6 92.2 37.4 5.6 97.4 24.6 15.5 3.5 2.1 34.7 14.6 24.8 20.2 46.6 19.3 32.4 2.7 13.6 65.7 17.1 98.8 27.3 39.1 34.8 32.8 7.3 24.1 69.7 33.0 22.7 C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 126.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 51.6;Cone photoreceptor cells: 83.4;Granulosa cells: 100.0;Theca cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 79.1;SK-BR-3: 44.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA030922: AB_2673660, HPA030924: AB_10669873" "unprognostic (3.02e-3)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (9.63e-2)" "unprognostic (3.15e-3)" "unprognostic (2.93e-2)" "unprognostic (2.39e-2)" "unprognostic (3.44e-2)" "unprognostic (3.00e-2)" "unprognostic (4.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" 39.9 126.3 18.6 8.3 18.0 1.3 23.3 18.4 19.8 12.0 16.9 12.9 4.9 8.3 8.4 10.7 9.4 8.3 7.5 16.4 18.6 10.1 8.6 7.9 9.7 21.8 20.9 18.9 11.3 29.2 7.2 5.2 20.2 17.3 5.8 24.6 10.8 11.5 2.8 15.6 9.0 7.8 20.5 41.4 11.7 3.3 23.4 6.7 8.5 4.1 7.9 12.8 11.4 26.1 13.4 5.5 3.9 8.9 79.1 21.7 15.1 9.3 14.4 5.7 5.2 8.7 15.0 0.2 5.0 18.0 14.0 1.5 13.9 9.7 7.2 0.9 6.2 2.3 7.1 7.1 10.6 1.0 0.0 14.0 8.9 30.3 11.7 12.5 27.1 0.7 8.4 0.1 15.3 1.2 1.9 2.7 21.4 5.7 18.7 1.4 5.7 8.0 8.5 27.8 6.3 2.8 10.1 44.6 8.1 7.6 11.7 5.9 9.3 13.5 1.9 4.5 7.6 5.0 7.9 1.1 39.2 7.7 2.8 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.1 0.5 0.3 0.1 0.3 0.1 0.0 0.3 0.1 18.6 18.0 18.4 19.8 16.4 18.6 21.8 20.9 20.2 20.5 23.4 26.1 24.8 3.2 15.5 20.5 4.4 4.1 9.1 7.6 15.9 51.6 8.2 7.0 3.1 8.6 8.3 3.7 83.4 12.8 4.4 3.4 0.0 5.6 0.3 6.0 6.7 19.3 4.9 5.9 20.3 8.5 4.8 11.9 17.9 8.3 0.0 100.0 46.1 5.2 3.6 1.7 14.4 6.9 6.1 7.0 10.5 0.2 3.7 5.6 1.8 24.4 2.5 3.6 3.1 11.6 18.8 8.1 5.0 2.2 8.1 15.9 3.0 2.5 7.7 36.9 13.1 7.4 17.9 0.1 3.0 14.3 2.6 9.3 2.8 82.4 6.9 16.6 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 115.8;liver: 336.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 46.4;Cardiomyocytes: 8.3;Club cells: 13.6;Fibroblasts: 19.1" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 58.5;HSkMC: 72.8;U-266/70: 17.1;U-266/84: 33.9" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" NA NA 342000000 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" 27.9 115.8 0.2 10.6 1.6 0.4 15.7 0.3 2.2 12.6 0.2 31.3 7.5 16.9 11.8 2.6 29.9 2.3 21.8 0.5 1.2 43.1 336.8 14.9 4.5 5.8 1.9 57.5 23.0 0.6 20.6 0.5 2.3 11.1 3.7 5.5 14.2 0.0 1.7 1.7 17.0 0.0 0.5 15.3 11.7 4.1 1.7 4.2 44.5 0.0 2.9 23.1 4.1 1.4 0.0 0.3 0.0 0.0 1.0 5.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.7 0.2 0.1 0.1 0.4 0.0 58.5 0.5 0.0 0.3 1.0 0.0 0.0 0.0 72.8 0.0 0.0 0.0 0.5 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.2 17.1 33.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.3 2.2 0.5 1.2 5.8 1.9 2.3 0.5 1.7 1.4 0.0 9.6 46.4 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 8.3 2.8 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.5 4.4 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 125.5;lymphoid tissue: 84.8" "Group enriched" "Detected in many" 4 "Hofbauer cells: 130.9;Kupffer cells: 228.3;Langerhans cells: 122.4;Macrophages: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 394.0" "Group enriched" "Detected in many" 42 "granulocytes: 394.0;monocytes: 115.9" "Cell line enhanced" "Detected in some" "A549: 3.9;CAPAN-2: 4.1;HMC-1: 4.7;U-87 MG: 6.2;U-937: 6.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" 72.7 18.2 3.3 84.8 3.1 125.5 8.5 2.4 9.0 11.8 21.6 9.8 2.5 7.5 1.4 8.3 23.9 38.8 11.7 3.9 8.2 9.7 18.0 43.1 11.5 8.9 6.9 5.0 8.9 4.8 51.8 31.8 8.4 5.3 4.2 4.4 5.1 2.5 1.9 2.3 5.8 28.1 5.7 38.2 7.2 2.6 10.5 7.1 3.6 5.8 4.3 37.1 4.6 11.6 1.0 3.9 0.1 0.1 0.7 0.2 0.6 0.7 0.5 0.2 0.1 0.2 4.1 0.3 0.7 0.9 0.4 1.4 0.2 0.5 0.2 0.7 0.5 0.1 3.8 0.6 0.4 1.5 4.7 0.3 2.2 0.4 0.3 0.6 0.0 0.2 0.2 1.7 0.1 1.1 0.2 2.5 1.2 0.2 0.3 0.2 0.1 0.3 1.3 0.9 0.0 0.0 0.3 0.3 0.6 0.5 0.2 2.2 0.0 0.1 2.1 0.3 0.1 0.2 0.3 0.3 6.2 6.5 0.2 41.6 53.8 38.8 0.4 80.4 0.3 0.4 0.3 0.2 6.1 0.6 0.3 0.3 394.0 0.5 115.9 1.1 0.3 19.3 3.3 3.1 2.4 9.0 3.9 8.2 8.9 6.9 8.4 5.7 10.5 11.6 4.4 3.2 20.8 0.0 5.1 5.1 1.0 3.4 2.8 1.0 2.1 4.4 2.9 1.5 15.3 1.8 2.1 0.8 1.5 1.6 3.9 0.0 1.3 17.3 1.8 6.3 0.0 0.4 1.5 0.0 1.5 5.3 1.1 4.6 25.2 0.1 2.9 8.3 130.9 0.0 0.6 0.8 4.1 228.3 122.4 1.3 0.6 446.7 5.4 5.6 56.3 0.2 0.0 1.0 0.3 0.1 0.1 0.0 4.9 0.5 0.7 1.3 40.7 4.3 13.1 4.1 2.8 0.5 0.9 1.4 3.0 1.5 3.3 0.0 1.3 0.5 C5orf49 LOC134121 ENSG00000215217 "Chromosome 5 open reading frame 49" A4QMS7 5 7830378-7851151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 29.1;choroid plexus: 27.4;fallopian tube: 75.7;testis: 37.1" "Group enriched" "Detected in many" 11 "Early spermatids: 821.2;Endometrial ciliated cells: 353.9;Late spermatids: 410.2;Respiratory ciliated cells: 502.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043759 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA043759: AB_2678655" "unprognostic (1.55e-1)" "unprognostic (5.82e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-2)" "unprognostic (2.13e-3)" "unprognostic (4.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (7.93e-2)" "unprognostic (7.54e-3)" "unprognostic (1.85e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (2.28e-2)" "unprognostic (2.20e-2)" 0.2 0.5 15.2 0.1 17.0 0.0 0.8 12.3 16.5 4.2 27.4 0.1 0.1 1.4 1.7 0.0 75.7 0.5 0.2 15.9 18.1 3.9 3.3 6.0 0.0 21.9 29.1 1.0 2.7 6.2 10.4 0.1 22.0 3.5 0.0 1.4 0.3 1.3 0.0 0.6 0.1 0.3 19.1 0.1 0.6 37.1 19.7 0.7 0.8 0.0 0.0 0.2 0.8 18.1 0.0 0.2 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.2 0.2 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 17.0 12.3 16.5 15.9 18.1 21.9 29.1 22.0 19.1 19.7 18.1 0.1 0.0 5.4 2.3 1.0 0.0 2.6 32.0 0.0 0.4 4.7 3.0 0.4 1.5 41.4 9.2 0.0 0.2 0.0 0.0 3.9 5.6 821.2 353.9 4.3 1.2 5.4 0.0 2.8 0.9 2.9 1.7 0.0 5.8 1.3 0.2 0.4 0.8 0.1 1.7 3.5 0.2 46.8 0.0 0.4 410.2 8.7 0.8 3.6 1.0 0.0 2.3 0.0 1.5 0.2 1.6 0.0 3.8 0.0 4.1 0.0 39.9 502.4 3.6 6.6 0.8 13.4 41.1 8.4 0.0 0.6 0.3 0.9 0.1 0.0 1.5 C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 665.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 127.2;Hepatocytes: 376.9;Late spermatids: 54.8;Leydig cells: 120.2;Respiratory ciliated cells: 58.0" "Group enriched" "Detected in many" 7 "liver cancer: 49.0;pancreatic cancer: 12.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 4.5;ASC TERT1: 6.2;HSkMC: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043823, CAB069427" Enhanced "Secreted to blood" NA NA 45000000000 9200000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB069427: AB_1614336, HPA043823: AB_10960262" "unprognostic (9.79e-2)" "unprognostic (1.96e-2)" "unprognostic (5.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (4.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (3.04e-3)" "prognostic favorable (4.31e-4)" "unprognostic (2.69e-4)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" 12.8 1.1 0.2 0.0 0.2 0.0 5.4 0.2 0.1 0.8 1.6 0.8 0.9 0.4 0.9 0.3 43.9 12.0 57.1 0.2 0.6 4.4 665.9 3.2 0.4 0.0 1.7 6.2 42.7 0.1 0.7 2.8 0.2 0.9 0.6 0.0 0.9 0.6 0.6 0.6 1.4 0.9 0.1 0.3 2.2 4.2 0.8 0.6 2.0 0.7 0.5 0.9 0.6 0.6 0.0 0.0 0.0 0.0 4.5 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.2 0.6 0.0 1.7 0.2 0.1 0.8 0.6 0.8 0.0 0.0 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 20.9 127.2 7.5 0.0 0.0 0.0 0.1 0.3 0.0 9.3 11.3 37.5 0.8 0.9 0.0 8.0 1.4 0.4 0.0 6.7 0.0 0.7 0.0 0.1 5.0 376.9 0.0 0.0 2.7 1.0 0.0 9.7 0.3 54.8 120.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.5 1.3 0.4 0.0 0.0 11.6 0.8 58.0 0.0 0.0 0.2 0.4 0.4 0.1 0.0 0.0 0.0 0.4 0.5 0.6 0.0 C6orf89 "BRAP, FLJ25357" ENSG00000198663 "Chromosome 6 open reading frame 89" Q6UWU4 6 36871870-36928964 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 340.1;Late spermatids: 699.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 351.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012548 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 89: Fibroblasts - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "HPA012548: AB_1845748" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "unprognostic (1.69e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.77e-5)" "unprognostic (3.75e-3)" "unprognostic (3.85e-1)" "unprognostic (9.94e-3)" "unprognostic (8.42e-3)" 37.4 37.5 24.6 27.3 28.8 37.6 32.0 26.1 24.6 45.8 22.7 33.8 28.1 36.8 50.0 35.4 38.5 33.1 49.7 26.7 31.2 32.9 34.1 32.8 24.7 29.0 29.4 44.9 46.2 54.3 28.2 33.3 29.1 37.0 37.1 13.4 42.3 47.6 36.6 24.2 27.5 45.0 29.9 24.9 33.4 47.5 30.2 30.2 58.2 44.3 31.4 31.7 26.5 35.3 37.9 22.9 31.1 44.8 111.0 76.2 18.3 73.1 91.6 50.5 55.2 23.7 39.2 33.6 55.5 150.6 54.1 40.3 38.3 46.0 72.9 60.4 33.2 48.8 23.3 26.8 55.5 39.6 48.3 66.0 56.2 62.0 58.9 60.4 44.5 60.1 93.8 90.1 79.0 37.7 43.5 15.0 11.6 43.1 25.7 21.1 30.9 61.1 33.7 33.2 54.9 39.5 48.8 23.5 50.8 25.8 56.0 53.3 52.7 72.3 41.2 57.6 57.4 48.4 63.8 351.0 32.6 55.8 77.3 28.1 16.7 20.9 18.1 16.4 17.9 9.8 14.8 16.8 14.7 9.1 10.2 11.2 27.2 11.2 22.5 9.2 16.4 14.4 24.6 28.8 26.1 24.6 26.7 31.2 29.0 29.4 29.1 29.9 30.2 35.3 31.2 38.5 56.8 22.9 24.6 6.8 23.9 28.8 19.4 15.5 24.6 19.0 67.1 41.5 31.6 38.6 10.4 34.0 26.6 39.2 19.6 41.2 340.1 24.9 36.1 36.1 17.4 56.0 38.4 58.1 41.6 37.7 27.5 33.7 30.4 52.6 25.0 45.5 40.0 23.5 35.3 27.9 32.6 29.8 12.5 699.2 45.1 27.2 10.6 29.0 24.9 53.9 28.8 31.7 54.5 56.3 27.9 50.8 44.1 26.6 30.5 20.1 28.3 12.8 19.7 35.8 36.9 33.7 38.5 23.5 8.9 46.0 28.5 50.8 25.9 26.1 C9orf116 "MGC29761, PIERCE1, RbEST47" ENSG00000160345 "Chromosome 9 open reading frame 116" Q5BN46 9 135495181-135501734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 97.2;testis: 62.5" "Group enriched" "Detected in many" 4 "Early spermatids: 520.9;Endometrial ciliated cells: 442.5;Late spermatids: 579.4;Respiratory ciliated cells: 610.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 41.3;T-47d: 41.9;U-2197: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021439, HPA065287" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA021439: AB_1845799, HPA065287: AB_2732732" "unprognostic (9.02e-2)" "unprognostic (1.36e-2)" "unprognostic (1.93e-1)" "prognostic favorable (3.53e-5)" "unprognostic (7.43e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" "unprognostic (4.23e-1)" "unprognostic (2.58e-1)" "unprognostic (5.30e-2)" "unprognostic (1.94e-1)" "unprognostic (4.88e-2)" "unprognostic (4.23e-3)" "unprognostic (3.86e-2)" "unprognostic (8.75e-2)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" 2.6 16.3 11.9 0.8 12.8 0.9 3.1 10.7 13.0 5.5 24.5 2.1 1.0 4.2 25.7 1.9 97.2 2.8 2.0 14.0 13.6 9.5 3.5 9.2 0.7 15.8 19.7 2.8 6.5 6.8 16.9 1.5 15.9 4.2 1.2 10.1 3.4 6.3 1.5 1.8 1.4 1.2 15.4 1.9 3.1 62.5 14.5 0.6 8.1 0.9 1.2 2.7 1.5 13.0 11.0 18.7 8.1 12.7 3.5 7.4 1.6 7.3 5.1 8.7 5.9 7.1 10.9 1.9 9.5 4.9 4.7 7.4 9.1 4.1 7.4 0.5 8.0 0.0 21.0 22.1 9.7 1.5 5.0 5.2 3.2 4.4 1.4 7.1 4.2 8.6 10.3 1.4 4.2 41.3 5.7 1.9 17.1 17.2 21.5 8.7 3.9 6.9 21.0 7.7 7.9 8.3 10.3 4.4 1.2 3.7 41.9 1.8 2.1 5.0 6.5 42.9 2.9 4.7 12.6 1.8 14.7 0.7 1.5 0.0 0.8 0.0 0.5 0.5 1.2 0.2 0.4 0.4 0.3 0.4 0.7 0.5 0.0 0.6 0.1 0.1 0.5 0.3 11.9 12.8 10.7 13.0 14.0 13.6 15.8 19.7 15.9 15.4 14.5 13.0 1.2 9.6 7.8 2.3 1.9 0.9 1.8 39.7 2.2 5.0 11.7 9.8 1.7 15.7 46.3 14.7 14.6 11.5 0.7 0.5 11.7 26.0 520.9 442.5 6.6 2.1 1.2 1.3 2.1 7.8 3.4 5.2 4.6 23.9 1.3 12.0 0.7 1.6 3.6 3.3 2.2 1.0 38.7 1.2 1.4 579.4 8.1 1.3 0.0 0.0 2.0 13.2 0.0 1.0 0.2 6.9 1.7 7.5 3.6 2.4 1.3 58.8 610.3 19.9 0.0 1.4 15.0 133.8 20.0 1.3 0.3 4.5 1.6 41.4 1.7 3.1 C9orf24 "bA573M23.4, CBE1, MGC32921, MGC33614, NYD-SP22, SMRP1" ENSG00000164972 "Chromosome 9 open reading frame 24" Q8NCR6 9 34379019-34397810 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 39.2;choroid plexus: 105.6;fallopian tube: 108.7;testis: 90.6" "Cell type enhanced" "Detected in many" "Early spermatids: 744.6;Endometrial ciliated cells: 841.0;Late spermatids: 3115.3;Respiratory ciliated cells: 1312.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053008 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Cytosol "HPA053008: AB_2682015" "unprognostic (3.62e-3)" "unprognostic (9.06e-3)" "unprognostic (1.00e-1)" "prognostic favorable (3.23e-5)" "unprognostic (7.66e-2)" "unprognostic (1.21e-2)" "unprognostic (2.40e-1)" "unprognostic (1.25e-1)" "unprognostic (2.72e-1)" "unprognostic (1.58e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.33e-1)" "unprognostic (6.39e-3)" "unprognostic (1.50e-1)" "unprognostic (7.43e-3)" "unprognostic (4.72e-2)" "unprognostic (1.90e-2)" 1.2 0.6 20.6 0.3 26.6 0.0 0.7 19.5 29.8 7.8 105.6 3.2 1.9 0.7 0.0 0.4 108.7 0.3 17.5 20.8 22.8 3.4 0.3 18.4 0.2 35.9 39.2 0.4 0.9 0.1 10.6 0.2 29.8 1.6 0.7 1.2 1.9 0.4 1.4 0.6 5.4 0.5 33.0 0.2 1.4 90.6 22.3 0.3 0.6 1.7 0.3 0.9 0.4 25.5 0.2 0.0 0.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.3 0.4 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.3 0.0 0.4 1.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.2 0.6 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.8 0.3 0.0 0.2 0.0 0.0 0.4 0.1 20.6 26.6 19.5 29.8 20.8 22.8 35.9 39.2 29.8 33.0 22.3 25.5 0.4 6.4 15.1 11.4 0.3 2.2 3.3 67.3 2.2 1.4 1.6 1.8 37.0 1.5 116.4 7.3 0.0 0.6 0.1 11.3 72.4 1.1 744.6 841.0 6.1 2.1 12.1 0.0 11.3 1.5 0.3 3.5 0.5 9.8 8.8 0.2 1.4 4.1 0.4 0.0 12.6 13.4 81.4 1.0 1.0 3115.3 10.5 2.7 0.0 1.0 0.0 2.2 1.0 4.0 5.4 0.2 7.3 7.2 0.5 4.5 142.5 13.7 1312.6 0.9 32.9 0.5 25.5 21.0 6.9 0.4 1.0 0.5 1.6 0.0 20.5 2.4 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 295 "salivary gland: 9393.1" "Group enriched" "Detected in some" 44 "Breast glandular cells: 77.9;Ionocytes: 99.7;Melanocytes: 179.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.6;naive CD8 T-cell: 16.4" "Lineage enriched" "Detected in many" 11 "T-cells: 16.4" "Cell line enhanced" "Detected in some" "Daudi: 1.7;U-2197: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" NA NA 24000000 "Cluster 32: T-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" 0.4 0.4 0.3 0.7 0.6 2.0 20.8 0.9 0.7 0.0 0.5 0.1 0.3 0.2 2.3 0.2 0.1 0.2 1.5 0.4 0.3 0.1 0.1 0.3 1.3 0.9 0.4 1.9 6.3 0.0 0.1 0.9 0.7 0.2 0.2 0.7 9393.1 0.0 0.4 31.8 0.5 0.0 0.1 1.2 0.4 0.3 0.7 1.2 0.3 0.0 1.0 0.1 0.0 1.8 0.2 0.0 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.3 0.4 1.7 0.1 0.1 0.4 0.3 0.1 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.0 0.5 0.5 0.0 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.4 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.3 0.2 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.6 0.3 1.3 0.2 0.4 0.1 0.4 0.1 0.4 0.4 1.4 0.3 0.2 0.3 0.2 0.3 0.3 0.7 2.7 0.0 0.5 5.6 16.4 1.3 0.4 0.2 0.3 0.3 1.6 0.3 0.6 0.9 0.7 0.4 0.3 0.9 0.4 0.7 0.1 0.7 1.8 0.2 0.0 0.0 0.0 0.1 0.1 0.1 1.4 0.0 0.0 77.9 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 99.7 0.0 1.3 0.2 0.0 0.2 179.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.6 0.5 0.0 0.0 CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 258.2;Glandular and luminal cells: 54.3;Oligodendrocyte precursor cells: 163.3" "Cancer enriched" "Detected in all" 5 "melanoma: 38.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "SK-MEL-30: 154.3;U-266/70: 216.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073649 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA073649: AB_2732233" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "prognostic favorable (4.71e-6)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (4.80e-2)" "unprognostic (7.81e-2)" 17.1 3.3 63.9 2.1 67.9 2.6 13.8 36.8 54.8 6.9 17.1 5.2 7.5 9.4 3.2 6.9 10.9 5.2 4.6 44.9 53.5 13.1 9.9 21.5 2.8 39.6 59.0 3.7 3.0 21.9 4.0 10.4 40.8 3.7 5.1 8.0 22.3 4.5 1.5 17.2 6.7 6.6 31.2 3.7 14.5 3.5 70.2 4.9 15.0 1.8 2.3 5.4 7.8 33.3 13.1 14.4 11.8 0.9 7.1 0.3 20.4 3.1 17.3 4.2 2.5 9.5 23.0 0.7 13.3 14.9 42.3 11.4 9.0 2.3 3.2 0.3 19.4 1.0 38.7 37.1 6.2 2.5 1.0 4.2 2.1 5.3 6.1 26.8 47.1 2.3 0.5 16.2 11.7 30.2 0.1 8.8 7.5 64.5 46.6 3.1 42.2 50.6 21.2 31.5 11.2 8.2 26.1 32.5 154.3 8.3 52.4 7.2 79.3 47.9 0.5 1.6 3.8 216.0 88.9 27.4 0.2 19.2 16.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 63.9 67.9 36.8 54.8 44.9 53.5 39.6 59.0 40.8 31.2 70.2 33.3 2.9 22.4 27.4 258.2 3.8 5.1 2.0 1.4 5.2 4.1 9.2 6.7 1.4 7.2 2.3 3.7 29.2 0.9 1.3 8.5 1.9 1.1 2.0 11.6 4.4 6.0 3.5 1.3 19.2 2.3 1.1 4.1 10.2 54.3 0.0 14.8 25.0 9.3 16.6 0.0 22.2 4.6 0.0 3.5 3.1 3.5 0.0 4.7 28.4 41.2 0.0 1.4 0.0 163.3 1.4 2.4 5.2 6.0 3.6 0.6 6.7 14.3 1.8 18.7 0.0 5.0 2.1 0.2 3.2 1.6 6.7 0.3 1.4 0.5 2.1 2.2 CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.2;Inhibitory neurons: 354.1;Microglial cells: 126.5;Oligodendrocyte precursor cells: 197.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 3.7" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "HMC-1: 22.7;RPMI-8226: 55.5;SK-BR-3: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020215 Uncertain Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane" "HPA020215: AB_1845860" "unprognostic (5.85e-2)" "unprognostic (4.90e-3)" "unprognostic (5.09e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (2.32e-2)" "unprognostic (2.95e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-3)" "unprognostic (1.53e-1)" "prognostic favorable (8.34e-8)" "unprognostic (1.14e-1)" "unprognostic (3.05e-2)" "unprognostic (8.09e-3)" "unprognostic (6.70e-3)" 0.1 6.6 7.0 0.2 4.3 0.7 1.8 2.3 10.4 6.0 0.0 1.5 1.7 3.7 7.3 0.5 7.7 2.0 0.6 3.6 0.8 2.2 1.0 3.7 0.1 0.0 1.2 0.5 2.8 1.2 3.5 0.6 0.4 3.0 1.5 4.3 0.5 1.8 0.2 0.7 2.4 0.7 3.5 1.8 0.8 1.6 6.1 0.2 2.9 0.2 0.1 0.6 0.1 6.0 0.0 0.5 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 2.7 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.1 0.1 0.0 0.4 0.9 0.0 0.0 0.2 55.5 0.5 3.6 4.7 2.1 0.3 10.1 1.1 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 4.3 2.3 10.4 3.6 0.8 0.0 1.2 0.4 3.5 6.1 6.0 0.6 3.2 36.2 7.8 0.6 0.9 0.8 4.6 2.2 33.3 7.2 1.8 2.3 10.0 9.1 1.8 35.5 0.9 0.5 3.0 0.0 7.2 4.9 4.3 40.1 2.4 59.4 2.7 251.2 2.3 0.2 3.4 5.1 3.3 12.6 1.7 0.0 3.4 0.2 8.4 354.1 3.8 2.0 0.8 4.0 8.3 4.4 2.1 5.4 126.5 0.5 4.0 0.0 197.5 29.9 3.8 5.6 27.1 0.1 1.7 9.5 2.7 9.5 12.9 0.0 0.2 8.6 1.0 3.7 0.5 1.0 0.3 1.7 9.6 7.6 0.9 CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 182.3;Inhibitory neurons: 36.0" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 192.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles NA NA 9700000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA034771: AB_10603555, HPA071829: AB_2686454" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" 1.0 0.6 4.7 1.3 5.2 1.2 1.2 9.9 6.9 1.4 0.3 1.6 1.2 1.6 0.9 0.6 1.1 0.7 8.4 0.7 13.9 2.3 0.3 49.1 1.2 8.3 8.4 2.1 4.3 2.5 7.1 1.8 14.0 3.0 1.9 8.6 1.3 1.1 1.8 2.6 1.6 1.2 4.8 1.4 4.1 6.5 11.4 1.0 2.2 1.5 0.5 0.5 0.7 2.1 0.0 0.1 3.0 6.6 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.0 0.6 0.2 24.8 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.4 0.0 1.1 0.1 0.2 7.9 0.2 0.5 0.2 0.0 0.7 0.0 0.0 18.6 192.7 0.6 0.4 0.0 5.5 1.5 0.0 0.0 0.1 1.8 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.9 0.7 0.9 0.7 0.0 0.5 1.2 0.7 0.0 0.9 0.0 0.1 1.2 0.4 4.7 5.2 9.9 6.9 0.7 13.9 8.3 8.4 14.0 4.8 11.4 2.1 0.4 76.9 182.3 4.2 0.4 1.5 0.4 0.0 1.8 21.5 2.5 1.7 4.6 0.0 2.5 1.8 20.9 0.0 6.8 0.8 0.0 0.2 0.7 0.1 0.4 0.6 1.2 2.7 7.8 0.0 0.0 1.5 3.1 0.2 20.3 0.3 0.4 0.0 0.1 0.0 36.0 11.0 0.0 0.0 0.4 4.0 0.3 0.4 0.0 1.9 0.1 4.3 15.5 6.0 0.9 0.4 0.3 1.9 2.9 0.7 0.2 0.7 2.2 9.8 13.1 2.4 2.4 2.6 11.2 0.2 0.6 0.3 2.9 3.4 0.6 0.3 CACNB2 "CACNLB2, MYSB" ENSG00000165995 "Calcium voltage-gated channel auxiliary subunit beta 2" Q08289 10 18140424-18543557 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.1" "Group enriched" "Detected in many" 5 "Astrocytes: 863.5;Excitatory neurons: 545.7;Inhibitory neurons: 357.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HAP1: 6.4;HSkMC: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035326 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA035326: AB_10669903" "unprognostic (3.03e-3)" "unprognostic (3.04e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (4.58e-3)" "unprognostic (4.67e-4)" "unprognostic (8.03e-2)" "unprognostic (3.76e-2)" "unprognostic (8.10e-2)" "unprognostic (1.70e-1)" "unprognostic (7.78e-4)" "unprognostic (1.40e-1)" "prognostic favorable (3.56e-5)" "unprognostic (3.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.03e-1)" "unprognostic (8.16e-2)" 2.8 9.4 1.3 2.1 3.9 1.3 3.8 5.4 12.9 7.4 0.1 17.6 1.1 12.8 2.7 5.0 10.1 2.2 17.8 5.4 7.4 3.2 10.7 3.9 0.9 0.0 0.1 13.6 7.5 0.6 19.3 0.5 0.0 8.5 3.2 35.1 3.9 8.8 1.1 4.2 11.4 5.3 0.0 1.5 7.7 2.1 2.2 0.7 2.5 0.7 0.2 16.8 4.6 1.5 0.2 1.0 0.7 0.5 0.3 0.3 0.5 0.3 0.0 0.0 0.3 0.4 0.5 0.9 0.2 0.2 0.3 0.7 6.4 0.0 0.0 0.3 2.4 0.8 1.7 1.5 1.6 0.5 1.5 8.1 0.0 0.0 0.0 0.3 0.0 1.4 0.9 1.6 0.0 0.7 0.8 1.0 2.4 0.0 0.0 0.7 0.7 0.8 0.0 0.8 2.9 0.8 0.1 0.0 0.4 0.8 0.1 0.9 0.0 0.6 1.5 0.3 0.6 1.6 1.8 1.7 0.2 1.2 0.3 1.4 0.1 0.2 0.2 0.2 0.4 0.4 0.3 0.1 0.0 0.5 0.5 0.8 0.1 0.3 0.2 0.2 1.1 0.0 1.3 3.9 5.4 12.9 5.4 7.4 0.0 0.1 0.0 0.0 2.2 1.5 2.1 0.0 0.6 863.5 0.1 3.3 1.3 0.0 1.8 31.9 1.1 1.3 22.4 0.0 0.0 0.0 108.4 0.4 0.7 2.8 1.9 0.4 0.9 1.1 13.9 1.5 37.1 0.8 545.7 0.2 0.0 3.0 0.0 2.6 0.0 3.8 0.0 0.9 0.1 8.4 357.8 9.4 0.0 0.0 1.1 0.8 0.9 0.5 1.8 96.5 0.0 15.9 0.0 95.5 13.7 0.2 2.4 4.5 0.3 2.1 5.9 0.8 0.0 75.7 6.6 2.6 14.2 0.1 0.1 0.0 4.1 0.3 1.0 5.3 5.7 1.3 CACNG1 CACNLG ENSG00000108878 "Calcium voltage-gated channel auxiliary subunit gamma 1" Q06432 17 67044554-67056797 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 55 "skeletal muscle: 327.7;tongue: 121.8" "Cell type enriched" "Detected in single" 27 "Skeletal myocytes: 8.1" "Cancer enhanced" "Detected in some" "breast cancer: 1.6;head and neck cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 2.9" "Region enriched" "Detected in single" 6 "basal ganglia: 3.4" "Not detected" "Not detected" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (1.76e-1)" "unprognostic (9.83e-3)" "unprognostic (1.75e-5)" "unprognostic (2.60e-1)" "unprognostic (6.72e-3)" "unprognostic (2.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.84e-3)" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (3.03e-1)" "unprognostic (1.94e-1)" 0.0 1.6 0.6 0.0 0.7 0.0 0.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 3.3 0.0 327.7 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.6 0.0 121.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.6 0.3 0.2 0.2 0.2 0.2 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.6;placenta: 80.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 146.4;Excitatory neurons: 35.5;Fibroblasts: 39.5;Horizontal cells: 35.3;Inhibitory neurons: 40.5;Muller glia cells: 39.4" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 65.0;HSkMC: 218.8;hTERT-HME1: 118.5;WM-115: 60.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" NA NA 800000 "Cluster 6: Brain - Smell perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" 17.3 7.9 102.0 15.1 139.6 0.1 9.2 151.6 145.4 27.6 1.2 28.2 4.4 3.9 1.3 11.5 9.2 6.2 18.1 143.1 96.2 2.2 0.6 5.0 14.3 87.4 84.1 1.5 2.2 0.2 31.0 80.6 120.7 5.1 14.4 66.8 5.9 4.7 2.3 13.0 15.8 6.1 66.3 13.3 11.1 3.0 99.4 1.2 7.3 6.5 9.8 16.2 31.0 60.8 0.0 0.0 0.6 0.0 4.2 1.2 0.0 0.0 0.0 9.4 1.8 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.0 0.0 3.8 0.0 0.0 3.7 0.0 0.0 65.0 0.0 0.2 218.8 0.0 0.1 118.5 0.0 5.3 0.0 0.0 0.2 2.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.1 4.1 0.0 0.0 5.0 0.0 0.1 9.1 0.0 32.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 60.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.0 139.6 151.6 145.4 143.1 96.2 87.4 84.1 120.7 66.3 99.4 60.8 4.2 0.0 0.5 11.4 0.0 6.6 0.1 0.0 0.6 146.4 0.1 0.8 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.0 0.0 0.2 8.0 0.0 0.0 35.5 0.0 0.8 39.5 0.5 0.0 0.0 0.0 3.6 0.0 1.2 35.3 40.5 0.0 0.0 0.0 10.7 8.3 0.6 0.3 24.9 1.9 0.0 39.4 0.0 18.6 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.6 0.0 16.3 3.6 3.1 2.6 0.3 4.3 0.7 0.6 0.0 0.0 0.1 CALB2 CAL2 ENSG00000172137 "Calbindin 2" P22676 16 71358713-71390436 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 100.5;brain: 131.9;breast: 53.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 97.8;granulocytes: 251.5;Granulosa cells: 44.1;Theca cells: 70.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "hypothalamus: 76.3;medulla oblongata: 89.5;midbrain: 42.2;pons: 86.7;thalamus: 131.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 21.5;HEL: 63.9;HMC-1: 133.0;U-2 OS: 38.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 449.0" "CAB000106, HPA007305, HPA007306" Enhanced Supported Enhanced Cytosol NA NA 9600 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "CAB000106: AB_2068519, HPA007305: AB_1078386, HPA007306: AB_1078385" "unprognostic (1.10e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.78e-5)" "unprognostic (1.75e-3)" "unprognostic (5.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.55e-3)" "unprognostic (4.28e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-3)" "unprognostic (1.35e-2)" "unprognostic (5.54e-4)" "unprognostic (1.97e-3)" "unprognostic (6.30e-2)" "unprognostic (4.72e-2)" "unprognostic (1.04e-2)" 100.5 36.6 19.9 4.1 15.4 0.0 53.5 16.5 20.0 3.5 4.1 13.8 0.7 0.7 0.5 7.7 7.7 1.1 7.7 12.8 76.3 0.3 0.2 3.6 0.1 89.5 42.2 11.4 0.7 0.0 14.3 0.0 86.7 0.9 4.7 23.6 11.1 0.4 0.5 4.9 6.2 1.7 16.0 0.1 1.0 13.0 131.9 0.1 0.2 0.2 0.9 2.0 2.7 8.4 19.1 2.0 17.0 0.0 0.6 0.1 3.3 0.6 0.3 0.5 0.1 0.1 21.5 0.0 0.3 0.2 2.7 3.7 0.0 0.0 0.2 0.1 0.1 63.9 0.0 0.6 0.1 0.0 133.0 0.0 0.0 1.3 0.2 0.3 0.0 1.6 0.0 0.5 0.1 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.1 0.2 0.1 0.6 0.0 0.1 0.0 3.1 38.0 0.3 3.8 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 15.4 16.5 20.0 12.8 76.3 89.5 42.2 86.7 16.0 131.9 8.4 0.5 9.6 7.2 0.3 0.0 0.3 0.1 0.2 0.0 12.5 10.3 2.3 0.4 1.5 0.0 0.0 6.2 0.0 0.0 0.0 0.0 1.8 2.6 0.3 10.8 0.7 0.0 0.0 0.4 97.8 0.1 29.6 0.0 0.1 251.5 44.1 0.0 0.1 0.1 30.3 17.4 0.0 0.0 0.0 0.4 2.4 6.2 1.2 5.4 1.0 0.0 2.5 0.0 0.0 0.6 16.5 0.0 0.0 0.1 0.1 0.0 0.0 1.5 10.3 0.0 0.2 1.9 1.8 5.0 0.0 0.0 0.1 3.5 70.2 0.0 0.2 CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 75.1;Fibroblasts: 38.2;Hepatic stellate cells: 48.2;Hofbauer cells: 53.7;Leydig cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 45.1;BJ: 37.7;BJ hTERT+: 37.5;fHDF/TERT166: 43.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" 49.7 18.5 7.2 12.5 6.5 2.1 38.9 6.3 9.0 54.4 7.0 18.4 6.5 58.1 5.5 12.2 43.3 21.6 34.2 7.0 7.3 10.7 4.5 23.2 13.7 8.0 6.4 48.1 7.1 3.1 7.3 10.0 7.8 21.1 4.3 0.4 14.9 10.6 9.7 17.9 19.6 15.9 7.7 35.3 13.8 11.5 8.0 5.6 21.6 11.1 6.1 33.9 39.3 7.9 11.0 7.5 1.8 2.4 27.3 45.1 9.1 37.7 37.5 11.2 15.7 3.3 5.3 3.3 4.2 43.2 0.7 5.0 3.8 0.0 2.1 0.4 21.5 7.8 2.5 0.6 12.4 1.3 0.7 15.6 0.0 3.3 0.1 20.8 13.5 8.3 1.8 19.8 7.5 25.0 3.0 3.7 4.8 2.3 6.7 9.2 3.0 7.5 1.0 0.9 5.3 2.3 1.5 6.2 2.1 0.8 1.2 2.5 24.5 3.6 4.4 12.6 2.7 3.0 7.6 3.8 31.0 24.0 0.8 70.0 91.9 1.8 83.7 178.4 69.6 27.7 56.5 69.7 152.1 7.3 10.8 42.3 3.6 62.9 214.6 17.8 82.7 85.6 7.2 6.5 6.3 9.0 7.0 7.3 8.0 6.4 7.8 7.7 8.0 7.9 18.2 3.2 0.6 1.0 4.9 5.4 2.9 0.6 4.0 0.1 3.4 4.4 3.3 1.5 0.0 3.7 0.0 3.1 11.3 0.1 0.0 4.2 1.0 1.4 19.8 25.5 1.2 5.7 2.3 0.2 75.1 38.2 1.5 2.1 8.8 11.4 48.2 0.6 53.7 0.0 0.5 0.1 2.0 28.8 18.8 2.5 45.7 21.5 8.8 2.8 17.3 0.2 33.0 1.0 0.2 0.1 0.1 16.1 3.1 0.8 0.0 0.3 0.0 0.1 19.7 16.8 27.9 0.8 0.9 0.8 3.8 19.2 19.4 6.0 0.0 1.0 CALML5 CLSP ENSG00000178372 "Calmodulin like 5" Q9NZT1 10 5498697-5499570 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 3060.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 172.1;Breast myoepithelial cells: 156.1;Suprabasal keratinocytes: 390.7" "Group enriched" "Detected in many" 6 "breast cancer: 97.6;cervical cancer: 189.1;head and neck cancer: 206.0;melanoma: 222.1;urothelial cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "A-431: 400.3" "Not detected" "Not detected" HPA040725 Enhanced Approved "Plasma membrane,Cytosol" NA NA 48000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA040725: AB_10793863" "unprognostic (7.68e-3)" "unprognostic (5.06e-3)" "unprognostic (5.64e-2)" "prognostic favorable (2.59e-5)" "unprognostic (4.82e-2)" "unprognostic (2.67e-1)" "unprognostic (1.37e-1)" "unprognostic (8.27e-2)" "unprognostic (1.14e-1)" "unprognostic (2.79e-1)" "unprognostic (1.71e-1)" "unprognostic (4.99e-2)" 3.9 0.5 0.0 0.0 0.0 0.1 41.2 0.0 0.0 94.0 0.0 0.8 0.0 0.3 0.7 67.5 0.1 0.0 1.3 0.0 0.0 0.3 1.7 0.8 0.0 0.0 0.0 0.4 1.1 0.0 0.5 0.0 0.0 0.5 0.0 0.0 554.0 0.0 11.7 3060.6 0.6 0.0 0.0 0.4 0.8 1.0 0.0 9.2 0.6 0.0 13.4 0.1 306.6 0.0 400.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.8 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 27.3 0.3 2.2 0.0 0.0 172.1 156.1 0.2 0.0 1.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 11.1 0.0 0.0 0.4 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 1.3 0.2 0.3 6.8 390.7 0.0 1.2 0.0 0.0 3.3 CAMK1 "CaMKI, CaMKI-alpha" ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757347-9769992 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 58.3;Hofbauer cells: 76.2;Macrophages: 71.2;Sertoli cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 280.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 280.5" "Cell line enriched" "Detected in many" 4 "HMC-1: 403.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol NA NA 110000 "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB031904: AB_630964, HPA051409: AB_2681473" "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 52.4 99.7 50.1 17.2 48.9 5.1 37.2 39.9 61.0 27.0 31.8 33.6 9.2 31.8 13.7 8.0 37.0 11.1 20.5 61.2 46.3 24.9 36.4 23.9 11.1 37.8 41.7 41.2 8.4 14.4 21.6 6.7 38.8 31.1 10.6 5.9 9.8 19.7 7.1 7.9 16.5 26.0 36.8 16.7 21.7 29.8 46.9 4.3 19.5 7.8 15.0 28.4 18.3 46.1 0.5 16.4 12.6 0.0 64.7 24.3 32.6 38.4 21.1 43.1 40.4 24.1 3.0 1.1 9.0 26.0 6.2 2.7 0.0 5.0 27.0 0.4 95.4 53.5 32.1 34.1 35.9 4.5 403.3 25.3 4.1 60.6 6.7 35.4 36.8 0.9 7.2 1.2 16.3 10.3 0.3 38.8 9.0 0.4 25.7 0.3 0.4 1.1 25.9 2.8 4.2 16.7 6.6 0.7 4.0 5.3 4.1 67.2 19.6 19.8 24.4 28.0 48.7 0.4 0.3 1.0 41.5 14.7 3.0 17.8 21.3 280.5 0.3 42.2 0.1 0.1 0.4 0.2 14.1 0.2 0.3 0.1 1.0 3.6 43.0 0.4 2.0 4.7 50.1 48.9 39.9 61.0 61.2 46.3 37.8 41.7 38.8 36.8 46.9 46.1 58.3 0.0 3.1 17.9 2.8 5.0 19.2 3.4 5.7 9.9 5.2 4.6 0.1 12.8 2.1 11.0 2.1 0.4 3.0 2.6 9.8 14.4 1.8 1.8 14.9 22.8 6.0 4.8 25.6 4.0 1.2 23.3 5.6 3.1 30.5 16.7 30.4 23.5 76.2 0.0 14.5 2.3 0.0 46.4 40.2 7.2 36.1 71.2 5.4 8.4 36.7 39.4 3.1 6.6 2.7 5.5 2.9 45.1 0.2 17.5 3.6 47.4 1.3 7.7 59.2 12.2 42.7 1.5 3.7 1.5 3.8 0.8 7.1 6.6 7.6 11.0 CAMK4 "CaMK-GR, CaMKIV" ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 70.4;lymphoid tissue: 55.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.9;Early spermatids: 306.2;Excitatory neurons: 212.2;Inhibitory neurons: 131.8;Late spermatids: 108.4;Oligodendrocyte precursor cells: 133.2;T-cells: 83.3" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "basal ganglia: 30.6;cerebellum: 70.4" "Group enriched" "Detected in many" 4 "MAIT T-cell: 24.3;memory CD4 T-cell: 17.3;memory CD8 T-cell: 13.5;naive CD4 T-cell: 33.1;naive CD8 T-cell: 18.5;T-reg: 21.3" "Lineage enriched" "Detected in many" 23 "T-cells: 33.1" "Cell line enhanced" "Detected in many" "HDLM-2: 88.9;JURKAT: 61.3;MOLT-4: 27.9;SH-SY5Y: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 0.4 3.8 5.0 4.4 30.6 3.1 0.4 70.4 8.2 0.9 0.0 1.3 1.4 0.6 0.3 0.7 0.3 1.5 0.1 7.6 0.0 0.7 1.4 1.1 8.1 0.0 0.4 0.6 0.4 0.0 0.6 0.2 1.4 3.4 1.4 4.7 0.4 1.4 0.1 0.1 2.3 0.8 0.0 2.6 1.5 9.4 0.8 55.4 0.2 0.0 5.2 1.7 0.4 0.0 0.0 0.0 3.1 2.1 0.6 2.3 0.0 0.8 6.8 8.0 7.8 0.0 0.1 0.0 4.0 0.4 5.4 0.3 6.8 0.8 5.8 88.9 5.2 1.3 2.8 0.0 0.2 0.6 0.3 0.3 0.0 16.8 1.7 4.9 1.4 61.3 0.0 3.3 0.4 0.0 27.9 0.0 4.1 0.0 0.2 4.0 5.0 0.2 2.9 0.1 18.8 33.5 1.2 0.0 5.6 0.2 0.1 0.5 0.1 16.3 9.5 0.1 14.7 2.6 0.3 0.0 8.0 0.0 6.3 0.1 0.0 0.0 4.8 0.0 24.3 1.3 17.3 13.5 0.0 0.3 33.1 18.5 0.9 1.4 0.0 0.1 21.3 5.5 5.0 30.6 70.4 8.2 7.6 0.0 0.0 0.4 1.4 0.0 0.8 0.0 1.8 0.0 1.1 57.8 9.4 1.1 0.3 1.3 8.6 70.9 0.6 0.6 5.3 0.0 0.0 0.0 0.0 0.1 3.1 0.1 0.0 0.1 306.2 0.2 1.6 1.1 0.0 0.0 212.2 0.0 0.2 4.6 3.6 0.4 4.5 0.3 0.7 0.3 0.2 0.0 131.8 0.8 0.0 1.3 2.1 108.4 4.1 2.0 0.0 12.2 2.7 2.8 1.0 133.2 5.4 1.2 0.0 1.5 11.5 0.5 0.0 0.1 0.1 4.3 0.0 0.6 3.8 30.3 6.2 2.4 1.0 0.0 83.3 0.1 0.0 0.3 CAMSAP3 "KIAA1543, Nezha, PPP1R80" ENSG00000076826 "Calmodulin regulated spectrin associated protein family member 3" Q9P1Y5 19 7595863-7618304 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 40.0;Gastric mucus-secreting cells: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 26.7;Hep G2: 15.6;MCF7: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043830, HPA062149" Enhanced Approved Nucleoplasm,Centrosome NA NA "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Centrosome" "HPA043830: AB_10795879, HPA062149: AB_2684698" "unprognostic (3.83e-2)" "unprognostic (1.18e-1)" "unprognostic (8.67e-2)" "unprognostic (7.90e-3)" "unprognostic (3.66e-1)" "unprognostic (3.87e-3)" "unprognostic (7.00e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (1.41e-1)" "prognostic favorable (7.55e-7)" "unprognostic (2.16e-2)" "unprognostic (3.88e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-3)" 0.4 3.3 3.2 0.8 4.4 0.0 5.3 2.5 9.0 7.7 0.1 10.3 14.9 0.5 2.3 24.8 3.1 1.6 0.4 4.2 0.7 12.0 24.3 4.6 0.2 2.5 0.0 0.5 20.6 2.7 8.2 0.4 0.4 10.2 2.4 3.2 18.1 4.5 0.2 62.7 11.5 0.1 0.0 0.6 15.5 13.0 0.2 0.5 11.1 0.0 1.1 3.6 13.4 2.4 11.2 1.8 0.3 0.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 26.7 5.8 3.1 4.5 0.0 1.2 9.7 4.3 2.8 0.0 2.0 10.1 0.0 0.5 15.6 0.0 0.0 4.4 0.0 5.5 0.0 0.4 0.4 0.0 4.5 0.9 0.0 0.0 13.0 0.2 0.2 6.6 8.4 4.7 0.7 0.0 3.7 1.9 6.0 8.2 8.7 1.3 12.5 0.0 1.6 10.4 1.7 0.0 0.0 2.0 0.0 0.4 5.0 1.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 2.5 9.0 4.2 0.7 2.5 0.0 0.4 0.0 0.2 2.4 0.2 9.6 19.2 3.3 1.1 9.8 2.7 2.4 3.4 22.7 19.3 12.1 1.5 20.0 5.3 9.2 0.0 0.5 0.2 40.0 3.9 5.7 4.4 9.6 1.4 1.5 13.1 0.0 9.1 11.8 0.7 0.2 38.7 13.5 5.7 8.6 0.4 24.8 0.2 10.1 10.1 22.4 0.0 1.9 1.2 2.9 1.5 1.0 0.0 1.9 0.0 1.5 0.0 4.5 0.6 13.1 28.4 0.0 0.6 6.2 29.2 15.6 2.9 13.4 0.0 0.0 1.1 0.4 2.8 9.8 18.9 0.5 0.9 1.5 18.4 8.0 CAPN13 FLJ23523 ENSG00000162949 "Calpain 13" Q6MZZ7 2 30722771-30820542 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.2;stomach 1: 28.5" "Cell type enhanced" "Detected in many" "Club cells: 76.6;Gastric mucus-secreting cells: 50.0;Proximal enterocytes: 35.2;Undifferentiated cells: 18.1;Urothelial cells: 19.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 9.3;SK-BR-3: 21.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029496, HPA029497, HPA030034" Uncertain Approved Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA029496: AB_2673072, HPA029497: AB_2673073, HPA030034: AB_2673281" "unprognostic (7.42e-2)" "unprognostic (1.19e-1)" "unprognostic (7.01e-3)" "unprognostic (1.96e-1)" "unprognostic (8.56e-2)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (1.32e-3)" "unprognostic (2.17e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.96e-2)" "unprognostic (3.64e-1)" "unprognostic (3.32e-2)" "unprognostic (5.03e-2)" "unprognostic (4.28e-3)" 0.0 0.0 0.8 0.0 1.4 0.0 7.2 0.9 1.3 9.7 1.0 11.4 20.8 0.2 0.3 0.9 1.1 2.8 0.0 0.7 0.8 2.5 0.2 7.2 0.0 1.1 1.3 0.0 3.6 0.4 0.2 0.0 1.0 3.8 24.6 0.0 1.2 0.1 0.0 0.2 29.2 0.2 1.0 0.1 28.5 0.1 1.1 0.0 0.0 0.0 0.6 4.1 0.5 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 9.3 0.1 0.4 0.0 21.9 0.0 0.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.9 1.3 0.7 0.8 1.1 1.3 1.0 1.0 1.1 2.3 0.0 6.4 3.1 0.3 0.0 0.0 10.2 3.5 4.0 0.0 4.2 1.8 1.3 0.0 76.6 1.8 0.0 0.0 0.0 16.9 0.0 1.3 0.8 2.0 0.0 0.1 15.0 0.0 0.3 5.3 0.0 0.6 50.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 1.5 12.0 6.1 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 8.4 1.9 6.2 0.0 0.0 2.7 35.2 0.2 12.4 0.0 0.0 0.0 6.1 0.0 0.1 1.4 0.0 0.0 0.1 0.0 18.1 19.4 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CASKIN2 "ANKS5B, FLJ21609, KIAA1139" ENSG00000177303 "CASK interacting protein 2" Q8WXE0 17 75500261-75515537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.5;Endothelial cells: 42.2;Hepatic stellate cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071906, HPA075184" Enhanced Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA071906: AB_2732191, HPA075184: AB_2732281" "unprognostic (1.60e-1)" "unprognostic (4.54e-2)" "unprognostic (9.12e-3)" "unprognostic (5.27e-3)" "unprognostic (9.32e-2)" "unprognostic (5.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.10e-2)" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "prognostic favorable (2.47e-5)" "unprognostic (1.82e-2)" "prognostic favorable (4.83e-8)" "unprognostic (1.43e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.95e-2)" 33.8 22.7 19.4 4.9 22.6 0.4 30.0 19.7 18.6 15.1 4.6 16.5 9.0 21.0 2.7 10.8 21.7 11.2 28.2 16.7 17.2 26.9 11.3 42.3 2.9 22.6 21.7 12.0 10.8 9.4 13.6 11.8 18.7 14.9 2.9 4.8 11.5 8.7 15.3 12.7 11.4 10.4 18.1 30.8 15.0 5.6 20.0 2.9 22.6 9.9 1.5 16.0 14.3 23.1 13.3 17.2 10.2 14.4 6.6 4.1 11.2 6.6 8.7 15.8 10.2 19.0 5.6 0.5 7.4 7.7 10.5 12.0 8.2 7.7 3.9 4.7 10.8 9.4 17.2 7.5 7.7 0.5 12.6 3.5 10.4 8.2 5.9 5.3 16.2 13.3 6.9 1.6 5.0 31.1 24.3 0.7 7.5 10.3 17.5 12.8 21.8 2.1 10.2 13.4 10.4 10.2 13.9 18.7 11.0 8.7 13.7 4.0 13.9 16.1 14.6 7.9 8.7 1.2 5.9 1.5 5.6 0.3 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 22.6 19.7 18.6 16.7 17.2 22.6 21.7 18.7 18.1 20.0 23.1 75.5 3.2 2.2 11.1 1.3 8.0 2.5 3.5 6.8 6.5 5.8 5.0 11.4 2.8 1.8 9.2 10.4 2.2 0.6 11.7 3.9 5.1 0.5 2.8 4.4 42.2 7.7 8.0 1.3 5.3 1.9 6.0 8.2 5.7 0.0 14.9 56.7 6.8 2.7 3.3 1.7 4.3 8.2 4.1 3.1 2.3 8.1 1.2 1.8 7.5 2.0 28.2 0.0 15.1 8.3 6.0 6.0 11.3 1.6 2.5 8.4 3.1 1.4 6.8 0.0 5.5 6.4 2.7 4.4 4.5 7.0 2.2 0.5 5.7 4.6 2.2 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CAT ENSG00000121691 Catalase P04040 11 34438934-34472060 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Mitogen, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1217.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 722.4;Hepatocytes: 443.4;Proximal tubular cells: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 13 "eosinophil: 4736.8" "Lineage enriched" "Detected in all" 13 "granulocytes: 4736.8" "Cell line enhanced" "Detected in many" "HL-60: 391.4;THP-1: 321.2;U-937: 265.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001515, HPA051282, HPA055838" Enhanced Enhanced Vesicles NA NA 760000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "CAB001515: AB_384710, HPA051282: AB_2681419, HPA055838: AB_2682937" "unprognostic (3.62e-2)" "unprognostic (2.72e-1)" "unprognostic (3.59e-3)" "unprognostic (5.43e-2)" "unprognostic (4.44e-2)" "unprognostic (5.80e-3)" "prognostic favorable (9.67e-4)" "unprognostic (9.95e-3)" "unprognostic (3.22e-1)" "unprognostic (7.23e-2)" "unprognostic (3.34e-2)" "unprognostic (9.77e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.01e-1)" "unprognostic (7.31e-2)" "unprognostic (4.77e-2)" "unprognostic (6.59e-3)" 281.3 115.1 27.1 52.1 29.6 407.7 123.6 27.9 35.5 82.0 39.4 82.6 145.1 53.1 34.8 40.1 86.8 59.8 58.1 26.6 29.4 296.6 1217.3 163.2 58.4 35.2 29.4 46.7 86.3 43.2 13.6 78.0 34.3 66.8 71.3 9.8 83.7 64.0 103.8 70.6 136.3 59.4 29.6 78.6 74.1 11.4 29.5 74.9 122.6 136.6 56.7 105.8 39.9 40.8 31.7 34.3 24.5 38.9 233.2 100.6 52.3 39.3 49.8 43.3 47.1 19.7 30.9 78.3 37.5 79.2 63.9 73.9 42.3 42.9 47.3 68.8 38.8 65.6 34.0 113.7 27.6 391.4 31.1 54.5 29.3 13.2 5.1 59.9 53.2 46.2 139.3 31.3 55.1 30.2 81.1 77.4 0.1 148.7 82.6 56.5 117.9 64.9 120.2 117.2 13.1 19.8 44.5 70.6 60.0 0.0 101.4 321.2 38.3 25.9 24.9 65.4 23.8 25.0 15.2 16.8 51.3 265.6 19.3 256.5 324.7 4736.8 54.4 265.1 64.6 133.9 63.7 61.0 353.5 124.1 61.7 66.7 290.2 105.7 298.5 235.8 92.7 397.9 27.1 29.6 27.9 35.5 26.6 29.4 35.2 29.4 34.3 29.6 29.5 40.8 196.9 227.6 275.9 41.1 53.8 28.9 93.7 44.9 27.9 13.5 42.6 36.1 44.9 82.9 66.9 73.5 27.1 96.8 92.0 59.4 225.0 36.0 2.7 72.2 41.4 43.8 48.0 722.4 12.6 26.2 30.0 53.1 54.6 29.3 24.0 38.7 57.1 443.4 138.5 0.0 1.2 56.9 91.6 125.5 95.8 6.2 78.3 93.9 26.6 16.9 253.4 19.5 28.8 22.6 45.6 15.3 44.8 77.5 25.4 37.0 151.6 333.2 96.9 19.4 78.9 46.6 68.0 6.3 11.3 24.4 27.1 40.5 37.7 57.7 95.6 97.5 CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 1296.7;Alveolar cells type 1: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 49.0;neutrophil: 24.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 49.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 162.3;HEL: 119.8;HUVEC TERT2: 362.3;LHCN-M2: 561.1;TIME: 148.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 88000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA039325: AB_10805473, HPA062122: AB_2684688" "unprognostic (6.85e-3)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-2)" "unprognostic (2.83e-1)" "unprognostic (1.46e-1)" "unprognostic (3.19e-2)" "unprognostic (6.14e-2)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.45e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (4.39e-3)" 164.9 25.1 17.9 13.0 20.1 6.5 60.9 16.9 20.2 56.8 13.1 69.4 11.5 38.9 13.2 48.2 53.9 51.8 96.7 15.1 16.5 25.9 31.2 93.9 15.3 19.5 17.3 53.0 22.5 12.9 7.1 34.0 19.5 30.2 24.9 1.1 7.1 30.0 32.3 6.9 21.1 58.1 15.9 111.9 15.0 4.3 22.3 4.1 78.3 59.9 5.6 42.7 19.5 17.0 0.0 20.2 6.8 0.1 1.0 3.4 0.1 4.1 3.5 0.8 1.5 0.0 0.0 0.1 24.8 162.3 0.0 3.4 0.0 31.8 2.3 0.1 0.0 119.8 1.4 45.6 43.6 0.0 0.0 8.4 20.5 3.4 9.6 2.2 362.3 0.0 43.9 0.0 561.1 0.0 0.0 0.1 0.1 0.0 1.0 0.0 32.3 0.2 41.7 0.0 0.0 0.1 0.0 0.0 0.0 9.1 0.0 0.1 148.9 0.0 12.4 7.4 0.0 0.0 0.0 0.1 0.0 1.0 0.0 49.0 2.4 1.2 0.2 0.8 0.3 0.1 0.0 0.0 2.3 0.3 0.2 0.0 24.3 1.3 1.5 3.1 0.5 121.3 17.9 20.1 16.9 20.2 15.1 16.5 19.5 17.3 19.5 15.9 22.3 17.0 1296.7 413.5 76.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.7 15.6 0.0 0.0 81.7 0.0 0.0 0.2 2.6 0.0 5.9 1.6 0.0 0.4 5.4 164.5 0.0 0.0 0.0 0.2 0.2 15.0 0.0 0.6 185.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.7 29.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.1 1.5 16.4 0.0 0.0 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.3;intestine: 50.9;skin 1: 42.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.6;Pancreatic endocrine cells: 95.0;Paneth cells: 108.1;Proximal enterocytes: 154.6;Undifferentiated cells: 67.1;Urothelial cells: 76.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 43.6;BEWO: 28.9;CACO-2: 28.3;CAPAN-2: 56.9;HaCaT: 41.0;HBEC3-KT: 34.8;hTCEpi: 26.0;OE19: 37.3;RT4: 34.7;SK-BR-3: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.1 0.0 3.1 0.0 0.0 5.1 0.0 0.1 8.0 0.0 25.0 50.9 0.9 0.1 39.3 2.5 4.4 0.0 0.0 0.0 7.4 21.1 1.3 0.0 0.0 0.0 0.1 20.6 1.6 0.5 0.4 0.0 11.8 11.7 0.1 13.3 2.4 0.1 42.4 38.6 0.6 0.0 0.0 17.7 0.7 0.0 0.3 1.7 0.0 4.0 8.3 18.4 0.0 43.6 0.0 0.0 0.1 0.0 0.0 28.9 0.0 0.0 0.0 0.0 28.3 56.9 0.0 0.0 0.0 0.0 41.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.3 0.0 0.0 0.0 0.0 0.0 34.7 0.4 0.1 0.0 31.1 0.0 0.2 22.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 15.0 44.0 30.8 16.5 0.0 9.3 7.4 0.2 4.3 27.7 7.3 0.0 5.8 0.2 108.6 1.9 53.8 0.1 7.0 1.3 0.9 17.4 0.0 0.4 48.9 2.3 0.5 59.7 15.5 0.0 0.0 0.0 11.1 0.3 0.0 0.9 40.0 18.3 0.0 1.4 0.3 0.0 0.4 0.0 0.0 0.6 0.0 0.0 1.0 0.3 95.0 108.1 0.0 0.1 34.4 154.6 17.2 9.8 0.0 0.0 0.0 1.3 0.0 2.6 29.9 25.7 2.5 0.7 0.0 67.1 76.9 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 114.2;testis: 31.9" "Cell type enhanced" "Detected in some" "Early spermatids: 100.9;Late spermatids: 291.0;Spermatocytes: 61.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "NTERA-2: 40.0;SCLC-21H: 126.0" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in many" 13 "cerebellum: 369.4" "Secreted in brain" NA NA 6000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" 11.8 1.0 4.6 0.2 3.2 0.0 3.8 114.2 7.1 2.1 0.9 0.7 1.0 5.8 0.4 1.0 1.3 7.5 4.6 2.4 23.4 0.2 1.0 0.1 0.8 10.7 18.4 1.3 2.8 0.2 4.2 0.0 12.7 0.5 0.7 3.5 0.6 0.6 0.9 0.8 1.3 1.7 4.8 0.1 0.7 31.9 27.0 0.2 2.3 1.7 2.8 1.4 0.5 5.4 0.0 0.0 0.6 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 2.7 2.6 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 126.0 3.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 114.2 7.1 2.4 23.4 10.7 18.4 12.7 4.8 27.0 5.4 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.3 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 100.9 0.1 2.4 6.7 13.2 0.0 0.6 0.4 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 4.7 0.5 0.0 0.0 0.0 291.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.2 0.0 0.4 0.0 0.1 0.3 0.0 0.0 1.8 26.3 0.1 19.2 61.7 5.8 0.0 0.1 0.0 0.0 8.8 0.2 0.0 CCDC107 MGC31967 ENSG00000159884 "Coiled-coil domain containing 107" Q8WV48 9 35658290-35661511 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016857, HPA050442" Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA016857: AB_10669751, HPA050442: AB_2681128" "unprognostic (3.70e-3)" "unprognostic (7.07e-3)" "unprognostic (3.60e-2)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.09e-2)" "unprognostic (4.13e-1)" "unprognostic (1.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.33e-2)" "unprognostic (1.89e-1)" "unprognostic (5.15e-1)" "unprognostic (1.96e-1)" "unprognostic (5.75e-2)" 91.6 61.0 35.1 19.1 34.6 7.8 75.3 37.4 40.6 48.5 36.0 117.8 19.2 74.2 31.1 25.1 60.6 15.3 90.3 34.5 35.3 37.7 50.3 43.6 15.4 35.5 35.7 32.3 62.7 12.8 33.0 13.9 36.0 55.9 16.8 13.9 26.6 29.2 64.4 32.5 47.1 28.2 34.7 41.2 74.4 17.1 37.3 26.0 31.4 22.4 14.4 76.6 39.1 35.0 17.9 15.7 12.8 16.3 63.3 40.3 7.4 29.5 26.4 18.5 17.2 7.2 5.2 11.5 12.8 38.9 47.6 5.9 9.6 14.2 13.6 34.4 15.3 5.5 25.1 18.3 15.0 8.5 20.1 24.1 16.6 19.8 15.3 34.4 13.1 19.2 7.2 21.7 23.4 11.6 9.5 12.6 9.5 12.6 48.2 13.7 2.9 9.3 62.8 9.6 8.4 14.0 15.2 21.1 15.4 9.5 11.1 10.4 16.7 29.5 16.3 21.6 27.3 9.6 15.4 23.1 54.6 13.5 26.2 33.3 39.3 20.1 128.7 43.2 168.8 79.5 111.6 113.8 45.0 79.5 53.2 74.2 7.8 69.3 25.9 123.8 140.8 75.1 35.1 34.6 37.4 40.6 34.5 35.3 35.5 35.7 36.0 34.7 37.3 35.0 68.7 67.3 25.0 11.1 104.8 70.2 38.0 76.9 8.6 31.9 39.2 65.3 0.7 60.1 48.4 82.8 8.4 15.0 175.2 143.9 17.6 74.1 7.6 33.5 34.1 36.1 88.1 15.8 8.6 140.2 66.2 60.0 121.8 30.5 34.3 24.4 53.9 77.3 90.9 32.0 10.2 100.5 69.2 46.9 185.9 28.3 59.4 82.0 113.8 13.1 43.5 57.2 133.9 7.5 10.8 86.7 108.6 102.3 53.3 45.3 146.7 66.9 48.2 34.1 118.3 33.7 135.3 37.9 63.1 17.8 66.9 13.8 132.7 44.9 51.7 29.5 CCDC178 "C18orf34, FLJ44050" ENSG00000166960 "Coiled-coil domain containing 178" Q5BJE1 18 32937402-33441101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.9;testis: 15.2" "Cell type enhanced" "Detected in some" "Adipocytes: 29.2;Early spermatids: 89.0;Late spermatids: 76.8;Spermatocytes: 49.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "HUVEC TERT2: 5.1;U-87 MG: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (9.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (2.58e-3)" "unprognostic (2.92e-1)" "unprognostic (5.95e-4)" "unprognostic (4.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.94e-4)" "unprognostic (2.86e-1)" "unprognostic (1.42e-3)" "unprognostic (9.03e-3)" 10.9 0.3 0.2 0.2 0.3 0.0 7.8 0.0 0.4 2.7 0.1 0.8 0.5 1.3 2.2 0.6 1.5 2.5 0.5 0.2 0.3 2.8 0.1 0.7 0.2 0.4 0.6 4.0 0.1 0.0 0.6 0.0 0.2 3.5 0.5 0.1 0.5 2.0 0.3 0.7 0.6 1.5 0.4 7.6 0.6 15.2 0.1 0.1 0.8 0.0 0.6 2.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.3 0.4 0.6 0.2 0.4 0.1 0.2 29.2 0.0 0.0 0.3 0.0 0.4 0.4 0.0 2.2 0.0 0.1 0.4 0.3 0.0 0.0 1.8 0.0 0.0 0.1 0.0 9.8 0.0 89.0 0.6 0.3 12.8 0.0 0.0 7.9 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 76.8 1.8 0.2 0.0 2.8 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.7 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 49.4 16.3 0.1 0.3 0.0 0.0 6.1 0.0 0.0 CCDC201 ENSG00000283247 "Coiled-coil domain containing 201" A0A1B0GTI1 7 45859994-45873082 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC3 DKFZp761F241 ENSG00000151468 "Coiled-coil domain containing 3" Q9BQI4 10 12896625-13099652 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 132.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 50.1;Excitatory neurons: 100.2;Inhibitory neurons: 41.3;Peritubular cells: 60.5;Smooth muscle cells: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 10.4;HAP1: 19.1;HDLM-2: 32.4;hTERT-RPE1: 14.8;U-2 OS: 20.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 20.8" HPA062425 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA062425: AB_2684759" "unprognostic (2.26e-1)" "unprognostic (6.65e-3)" "unprognostic (1.70e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (5.08e-2)" "unprognostic (3.11e-2)" "unprognostic (2.99e-2)" "unprognostic (5.56e-3)" "unprognostic (5.41e-2)" "unprognostic (4.25e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.54e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (3.88e-2)" 91.8 11.0 32.9 5.9 35.2 0.1 37.2 17.9 40.2 48.1 17.8 10.1 6.6 25.0 41.3 60.4 56.7 70.7 21.9 37.1 20.1 19.0 20.6 21.0 12.4 18.6 19.1 86.2 6.5 4.9 10.2 22.2 19.6 35.2 7.4 1.6 7.1 22.0 30.7 132.2 14.3 24.2 19.8 24.7 13.1 11.6 21.7 42.0 20.0 13.3 4.2 23.2 27.4 30.5 0.0 0.2 1.7 9.4 0.0 0.0 0.1 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.7 0.0 10.4 1.9 19.1 3.6 0.6 32.4 8.1 0.0 0.2 0.0 0.7 0.0 0.0 2.3 2.3 0.4 0.0 14.8 0.9 0.8 0.0 0.2 1.0 0.2 0.0 5.4 1.5 0.0 0.1 0.0 4.1 0.3 0.0 0.0 3.6 1.6 7.0 1.0 0.0 4.4 0.0 0.0 0.0 0.0 20.0 1.2 0.3 0.0 0.0 0.0 0.1 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.9 35.2 17.9 40.2 37.1 20.1 18.6 19.1 19.6 19.8 21.7 30.5 12.4 0.0 0.0 10.1 0.1 50.1 6.4 26.3 13.6 1.2 0.9 4.7 7.9 1.5 2.1 0.0 0.0 0.3 1.3 0.1 1.9 0.0 0.2 0.1 0.7 27.2 0.0 0.0 100.2 0.0 0.2 16.0 0.5 0.4 0.0 16.4 8.2 0.2 0.3 0.0 41.3 0.1 0.0 0.0 6.4 1.5 22.4 0.6 14.2 3.7 0.0 0.3 0.0 22.6 23.2 0.1 2.5 60.5 0.0 3.0 0.3 0.4 1.1 2.1 32.9 7.9 119.4 0.0 5.7 2.1 37.2 0.3 1.0 6.0 0.3 1.3 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC74A FLJ40345 ENSG00000163040 "Coiled-coil domain containing 74A" Q96AQ1 2 131527675-131533666 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 73.5" "Cell type enhanced" "Detected in many" "Early spermatids: 424.4;Late spermatids: 274.9;Respiratory ciliated cells: 166.1;Spermatocytes: 154.2;Theca cells: 211.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 28.6;SCLC-21H: 23.2" HPA060727 Uncertain Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA060727: " "prognostic favorable (5.11e-4)" "unprognostic (2.89e-3)" "unprognostic (6.49e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.91e-1)" "unprognostic (1.36e-2)" "unprognostic (2.18e-3)" "unprognostic (1.71e-1)" "unprognostic (2.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.70e-7)" "unprognostic (7.28e-3)" "prognostic favorable (4.92e-4)" "unprognostic (5.96e-2)" "unprognostic (3.53e-2)" 3.3 32.7 10.6 1.2 9.6 0.1 9.6 7.3 11.3 17.6 29.3 6.9 1.1 12.8 8.9 3.0 34.5 7.0 3.5 11.1 12.2 8.9 1.2 6.2 1.3 12.1 12.8 14.8 2.6 20.4 34.7 1.1 10.5 15.8 1.7 2.0 3.1 6.3 0.5 4.9 2.5 3.0 10.5 1.2 3.2 73.5 15.1 5.3 7.3 0.8 0.8 14.5 8.0 8.0 0.0 5.9 6.0 0.3 8.4 20.2 0.5 5.1 8.4 4.6 3.4 0.2 8.9 2.3 3.1 7.9 7.7 4.6 2.6 1.5 1.9 6.1 11.1 0.0 6.2 0.2 1.0 0.2 0.5 6.6 0.6 4.5 0.0 9.0 1.8 12.7 3.4 6.5 4.2 3.8 13.3 3.6 28.6 2.3 3.8 6.4 0.0 2.7 11.8 0.1 23.2 16.9 0.6 0.8 0.9 2.3 8.2 1.3 1.9 1.4 4.3 18.0 3.9 1.3 1.2 0.8 19.0 0.6 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 9.6 7.3 11.3 11.1 12.2 12.1 12.8 10.5 10.5 15.1 8.0 0.8 0.0 0.5 1.6 0.3 5.1 12.2 21.6 14.2 1.0 34.8 28.4 0.5 4.3 15.8 7.3 0.0 0.5 1.1 0.8 7.9 9.4 424.4 88.2 7.6 1.4 7.7 0.0 3.7 0.7 0.4 11.1 1.1 4.7 0.0 30.4 1.4 0.1 0.3 0.0 2.4 0.6 16.2 0.0 5.9 274.9 37.0 0.8 1.8 1.0 0.0 14.2 0.0 1.0 0.5 2.7 0.5 68.4 0.9 7.4 0.1 2.6 166.1 1.1 0.0 2.5 14.2 154.2 18.8 7.2 6.0 0.3 1.2 211.1 2.4 7.2 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCDC92 FLJ22471 ENSG00000119242 "Coiled-coil domain containing 92" Q53HC0 12 123918660-123972831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 89.2;Excitatory neurons: 123.0;Inhibitory neurons: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038560, HPA057580" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome Nucleoplasm "HPA038560: AB_10672717, HPA057580: AB_2683476" "unprognostic (4.77e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "prognostic favorable (7.15e-4)" "unprognostic (4.82e-2)" "unprognostic (1.79e-1)" "unprognostic (1.45e-1)" "unprognostic (5.01e-2)" "unprognostic (5.69e-2)" "unprognostic (7.14e-2)" "prognostic favorable (4.59e-5)" "unprognostic (1.24e-1)" "unprognostic (1.39e-1)" "unprognostic (3.08e-2)" "unprognostic (1.88e-1)" "unprognostic (1.07e-3)" "unprognostic (4.99e-2)" 56.3 26.7 18.5 3.7 17.4 1.2 47.5 2.9 44.2 39.8 0.0 53.6 5.8 40.4 7.1 20.1 37.7 4.0 77.4 24.3 4.8 39.7 38.4 37.7 3.4 17.6 6.3 35.5 21.1 5.5 58.5 7.0 18.6 36.3 2.7 7.2 24.8 4.7 77.8 17.4 34.3 5.5 4.6 27.0 32.9 74.0 14.3 3.2 40.9 7.6 2.4 37.5 28.7 20.0 4.9 5.5 2.7 4.9 17.5 9.6 4.9 8.1 15.3 4.5 4.8 2.9 1.4 2.4 2.7 10.2 2.5 3.4 3.0 2.1 3.0 15.0 7.0 3.1 2.2 1.8 9.2 0.5 11.3 5.5 9.2 5.7 3.5 13.7 12.6 5.3 3.2 1.1 4.0 3.3 3.0 5.4 1.2 2.4 11.6 3.7 1.5 0.7 6.1 5.1 5.1 7.3 4.0 1.9 5.7 6.3 5.7 2.7 12.6 8.9 1.9 5.8 2.8 3.7 2.1 0.7 7.1 4.2 3.9 1.6 0.4 0.7 0.7 0.2 1.2 0.5 0.9 1.1 0.3 0.5 0.6 0.9 0.4 0.5 0.0 0.4 0.1 0.6 18.5 17.4 2.9 44.2 24.3 4.8 17.6 6.3 18.6 4.6 14.3 20.0 17.6 19.2 28.5 52.5 8.3 3.8 7.5 8.1 4.0 33.6 14.2 11.7 40.8 18.6 8.6 18.4 14.6 4.4 16.4 7.2 7.9 14.7 89.2 15.1 13.0 17.7 4.8 4.4 123.0 10.9 2.7 19.2 10.2 14.5 20.3 31.2 18.9 14.5 18.9 21.9 106.1 6.2 8.2 12.0 6.3 63.9 13.7 14.2 8.8 30.9 9.9 15.0 22.6 50.8 70.0 15.5 2.7 17.3 3.2 9.5 10.0 37.0 9.0 13.6 72.3 15.3 24.6 40.9 10.1 6.3 3.0 5.6 13.7 26.3 7.6 7.5 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL18 "AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18" ENSG00000275385 "C-C motif chemokine ligand 18" P55774 17 36064272-36072032 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lung: 48.7" "Group enriched" "Detected in some" 5 "Hofbauer cells: 189.1;Langerhans cells: 104.3;Macrophages: 153.1" "Cancer enhanced" "Detected in all" "lung cancer: 76.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 55500000 6400000 "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (8.91e-2)" "unprognostic (2.96e-2)" "unprognostic (5.71e-2)" "unprognostic (9.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" "unprognostic (2.50e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.68e-1)" "unprognostic (3.63e-1)" "unprognostic (4.87e-2)" 9.7 0.3 0.0 2.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 2.0 3.9 0.1 0.0 0.9 0.4 0.0 1.6 0.0 0.0 0.2 0.3 48.7 7.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 2.5 0.0 0.0 0.9 9.2 1.5 0.0 4.0 0.2 0.5 0.1 6.1 1.1 0.0 5.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 25.4 0.0 1.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 0.0 0.0 0.5 4.2 0.0 0.0 0.0 24.5 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.1 0.0 0.4 0.7 189.1 0.0 0.0 0.0 0.0 4.2 104.3 5.3 0.0 153.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.4 0.9 0.0 0.1 0.1 3.4 1.6 2.9 0.0 0.0 0.0 CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.7;lung: 35.8;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in many" "dendritic cells: 441.4;Hofbauer cells: 2084.4;Kupffer cells: 723.2;Langerhans cells: 710.0;Macrophages: 1534.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.6" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.6" "Cell line enhanced" "Detected in some" "Karpas-707: 443.8;U-266/70: 602.5;U-266/84: 2043.3" "Secreted to blood" NA NA 138000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (7.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-1)" "unprognostic (8.90e-2)" "unprognostic (7.92e-3)" "unprognostic (2.00e-1)" "unprognostic (7.20e-2)" "unprognostic (2.05e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-2)" 17.6 16.0 0.0 8.1 0.7 76.7 5.6 0.0 1.4 1.5 0.0 2.5 0.0 1.1 0.0 0.5 2.9 10.3 3.7 0.0 0.0 4.6 12.9 35.8 1.8 0.7 0.0 1.2 1.3 0.0 1.7 2.4 0.0 2.2 0.0 0.0 5.6 0.0 0.8 0.8 3.1 0.0 0.0 49.4 3.0 0.7 0.5 0.0 2.0 0.0 0.0 3.0 1.4 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.8 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 55.6 0.0 0.0 1.3 602.5 2043.3 0.0 0.0 0.0 0.0 0.0 2.1 10.8 23.6 1.3 0.0 5.1 0.0 6.1 0.4 10.4 0.1 6.8 10.5 3.5 1.3 0.0 0.0 11.6 0.0 0.7 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.5 1.4 33.0 0.0 28.6 0.0 45.3 27.9 2.0 0.2 1.2 1.8 23.1 50.0 2.2 4.3 4.4 0.0 0.0 19.0 441.4 0.7 0.0 0.6 1.5 1.6 2.5 115.9 0.0 61.9 0.0 0.2 22.6 14.5 2.0 2.8 23.5 0.1 27.1 9.1 2084.4 0.0 0.0 0.5 0.0 723.2 710.0 1.9 1.8 1534.2 94.3 2.8 23.5 2.1 106.1 0.0 0.0 0.4 0.0 0.0 344.8 1.2 0.0 0.9 2.2 3.7 6.6 2.3 9.2 0.5 0.6 0.6 28.8 54.3 248.0 0.1 0.2 1.3 CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "dendritic cells: 3753.7;Hofbauer cells: 849.7;Macrophages: 1168.2;NK-cells: 1232.8;Plasma cells: 974.5;T-cells: 1948.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Group enriched" "Detected in some" 6 "U-266/70: 51.6;U-266/84: 13.3" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" 38.9 28.0 2.0 32.0 2.0 192.9 10.5 3.4 5.5 16.0 4.1 9.9 7.6 10.3 6.4 15.0 8.2 45.1 4.4 2.0 1.9 6.8 84.2 33.9 34.3 3.2 2.9 5.0 15.6 12.0 2.5 17.8 2.8 7.6 11.1 0.1 5.1 3.4 1.0 0.9 11.4 18.0 2.5 65.3 10.3 2.7 2.1 24.1 5.9 4.5 15.4 56.4 4.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 51.6 13.3 0.2 0.2 0.1 0.0 14.4 3.4 135.0 414.7 4.8 101.6 8.4 46.0 240.6 2.3 17.7 13.8 181.7 55.8 42.8 11.1 2.6 0.5 138.9 2.0 2.0 3.4 5.5 2.0 1.9 3.2 2.9 2.8 2.5 2.1 3.3 52.3 0.0 54.5 0.0 135.9 15.6 1.9 0.3 24.5 1.5 26.3 49.3 11.2 14.3 7.2 0.0 0.0 9.7 3753.7 1.2 0.0 0.4 20.8 3.7 4.7 77.6 1.2 60.9 0.0 0.4 11.3 18.9 118.3 5.5 60.8 0.2 21.4 10.5 849.7 1.7 0.0 1.5 0.0 429.4 428.0 32.6 0.9 1168.2 51.6 3.7 10.5 1.1 1232.8 0.0 0.0 0.2 0.1 0.4 974.5 0.8 0.4 2.8 5.8 5.2 0.0 3.9 20.9 0.4 0.4 11.0 14.5 25.9 1948.3 0.0 0.9 1.6 CCL4L2 ENSG00000276070 "C-C motif chemokine ligand 4 like 2" Q8NHW4 17 36210924-36212878 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.2;lymphoid tissue: 20.5" "Group enriched" "Detected in many" 6 "dendritic cells: 488.0;Hofbauer cells: 358.5;Kupffer cells: 163.4;Macrophages: 585.2;NK-cells: 249.3;T-cells: 303.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 7 "eosinophil: 122.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 122.0" "Group enriched" "Detected in some" 4 "Daudi: 4.1;HMC-1: 5.6;U-266/70: 8.8" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" "unprognostic (2.46e-2)" "unprognostic (1.44e-2)" "unprognostic (1.16e-1)" "unprognostic (6.07e-2)" "unprognostic (3.82e-1)" "unprognostic (3.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.14e-1)" "unprognostic (3.62e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-2)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" "unprognostic (8.51e-2)" "unprognostic (1.99e-3)" 5.5 3.8 0.3 4.4 0.3 32.2 1.5 0.5 1.1 0.9 0.4 1.7 1.5 1.1 0.5 0.7 2.6 6.8 1.3 0.4 0.3 3.1 7.6 12.6 3.2 0.3 0.3 1.9 0.9 2.0 1.1 2.2 0.3 1.9 1.8 0.0 2.0 0.7 0.2 0.4 3.8 1.5 0.3 20.5 1.8 0.2 0.3 1.6 1.4 1.7 0.8 4.8 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.8 1.5 0.7 0.0 0.0 0.0 0.6 0.3 122.0 15.2 0.3 3.6 0.0 0.6 8.9 0.1 0.1 0.1 8.4 18.2 1.2 0.2 0.0 0.0 5.5 0.3 0.3 0.5 1.1 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.4 18.1 0.0 7.7 0.7 13.9 0.4 0.4 0.0 5.7 0.4 13.8 22.9 8.6 4.3 0.0 0.0 0.0 4.2 488.0 0.2 0.0 0.1 0.2 0.4 1.0 38.1 0.0 14.3 1.1 0.0 6.1 3.9 3.1 0.8 5.1 8.2 7.1 1.3 358.5 1.7 0.4 0.1 0.0 163.4 59.1 1.2 0.0 585.2 1.8 6.5 3.3 1.3 249.3 0.0 0.1 0.1 0.1 0.0 50.6 0.4 0.0 0.2 0.0 2.3 13.1 1.1 6.6 0.1 0.1 1.4 0.4 9.6 303.6 0.1 0.0 1.8 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCM2 "C7orf22, MGC4607, OSM" ENSG00000136280 "CCM2 scaffold protein" Q9BSQ5 7 44999475-45076469 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 140.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020273, HPA021669, HPA065815" Supported Enhanced Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA020273: AB_1846185, HPA021669: AB_1846186, HPA065815: AB_2685562" "unprognostic (4.30e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.37e-3)" "unprognostic (3.92e-1)" "unprognostic (2.65e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.03e-1)" "prognostic unfavorable (5.06e-7)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (2.81e-2)" "unprognostic (2.48e-1)" 32.7 40.7 62.5 25.1 74.5 15.5 26.6 58.7 89.1 19.1 48.4 30.2 13.2 20.3 6.4 22.4 18.9 11.5 37.1 63.0 62.4 24.2 86.0 29.2 43.6 67.6 62.8 16.1 26.6 21.4 30.4 14.5 69.2 23.8 10.8 9.4 18.8 14.5 48.2 21.1 27.6 16.9 60.0 54.6 24.0 30.3 71.5 45.4 18.7 36.9 29.6 27.2 20.0 68.6 38.7 41.8 24.4 49.2 45.5 39.8 17.7 45.9 37.3 32.0 43.3 30.6 39.3 53.7 34.5 58.5 101.8 49.5 15.3 58.9 21.4 61.0 29.7 23.3 34.0 22.1 39.9 9.9 61.5 44.7 38.0 56.3 24.0 30.0 59.2 76.8 27.5 42.1 64.7 58.2 47.9 131.6 28.4 32.3 46.1 25.7 14.2 43.9 33.1 36.8 46.9 36.8 37.5 29.2 20.9 31.7 33.3 45.7 45.1 43.4 36.4 44.2 44.8 75.9 64.0 109.2 42.3 35.7 53.4 108.1 33.5 105.8 52.2 40.2 35.2 42.0 62.3 57.4 23.6 43.6 58.9 44.1 103.9 60.9 47.7 23.8 167.1 40.2 62.5 74.5 58.7 89.1 63.0 62.4 67.6 62.8 69.2 60.0 71.5 68.6 28.7 19.2 19.4 26.1 57.5 46.8 22.6 27.6 54.7 19.0 13.5 24.6 13.0 20.0 18.8 14.7 4.2 28.3 53.7 30.5 25.4 30.2 6.9 6.0 14.3 26.7 15.6 13.7 33.3 38.5 35.8 25.0 11.2 7.4 36.1 23.8 30.4 56.5 49.3 82.4 24.9 15.2 12.2 47.9 51.1 12.8 21.1 47.7 33.8 56.2 140.0 34.1 122.6 20.1 51.7 45.3 11.4 20.3 69.1 40.4 13.6 22.9 8.0 14.4 19.7 16.2 29.6 15.3 37.8 16.8 23.0 10.4 55.7 36.9 15.2 19.7 CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 141.6" "Cell type enriched" "Detected in some" 5 "Theca cells: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.2;HUVEC TERT2: 9.0;NTERA-2: 4.6;RH-30: 3.2;SCLC-21H: 7.7;TIME: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" 15.9 5.4 7.2 1.6 7.3 0.0 15.0 9.5 6.8 8.7 4.2 4.6 1.3 8.9 0.6 3.7 7.7 2.5 23.2 6.1 5.8 13.3 2.2 11.8 1.5 6.8 6.4 3.6 2.6 1.4 4.1 7.8 7.0 5.8 1.1 0.4 3.4 1.8 4.8 3.9 5.4 3.3 6.1 141.6 4.2 1.6 7.3 0.8 10.2 4.8 0.9 6.4 6.3 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 9.0 0.9 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.1 0.0 0.6 3.2 0.1 0.0 0.0 7.7 0.9 0.2 0.0 0.0 1.1 2.5 0.0 4.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 7.3 9.5 6.8 6.1 5.8 6.8 6.4 7.0 6.1 7.3 5.2 45.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.5 0.6 4.6 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.2 32.1 0.0 0.0 2.9 0.2 0.0 1.0 0.0 0.2 0.0 4.3 24.3 0.0 0.0 3.3 2.4 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.8 0.3 0.6 0.1 0.3 0.0 0.1 248.7 0.0 0.1 CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934934-42050357 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 256.6" "Cell type enhanced" "Detected in all" "NK-cells: 555.1;Syncytiotrophoblasts: 236.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 696.3;REH: 651.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA042871" Approved Supported Nucleoplasm NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "CAB000116: , HPA042871: " "unprognostic (4.53e-2)" "unprognostic (4.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (9.80e-2)" "unprognostic (3.40e-2)" "unprognostic (5.25e-2)" "unprognostic (7.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.17e-2)" "unprognostic (6.39e-2)" "unprognostic (2.45e-3)" "unprognostic (9.12e-2)" "unprognostic (1.71e-1)" "prognostic favorable (8.08e-6)" "unprognostic (2.11e-1)" 74.3 137.6 84.8 63.1 84.6 220.2 64.8 80.0 94.5 36.9 78.4 45.6 40.6 35.4 15.3 39.6 43.2 34.4 68.1 86.2 88.6 42.4 22.1 102.5 143.3 87.4 82.5 36.0 31.6 23.7 33.3 55.4 84.0 50.4 27.0 10.3 50.4 25.6 18.2 52.3 78.5 28.6 79.7 170.4 66.1 11.1 86.4 256.6 58.7 32.5 83.6 45.4 44.3 80.8 67.7 242.2 24.6 54.8 43.7 88.6 286.1 77.1 43.7 77.7 57.1 45.9 29.7 288.9 127.8 51.9 68.9 40.5 65.8 93.4 39.2 49.2 43.4 458.8 106.6 37.3 94.9 75.9 385.2 84.7 59.8 76.0 27.9 23.5 96.6 188.3 236.7 27.2 111.6 92.0 696.3 354.6 10.9 202.8 51.5 651.8 96.3 32.2 179.1 44.9 83.8 21.8 65.8 83.3 38.6 30.6 51.5 288.4 162.9 86.2 47.9 74.7 88.1 17.9 15.2 458.5 50.4 157.6 53.3 1281.3 246.3 725.1 390.4 294.4 276.5 127.1 266.4 318.1 343.3 180.8 306.4 328.3 339.3 333.2 405.6 221.4 193.0 635.4 84.8 84.6 80.0 94.5 86.2 88.6 87.4 82.5 84.0 79.7 86.4 80.8 102.2 60.9 67.9 31.0 102.9 27.0 95.8 52.3 48.9 19.6 49.9 45.1 26.2 64.3 27.8 20.2 6.2 201.0 227.3 66.4 29.4 20.3 12.8 12.1 10.8 68.3 9.6 133.6 37.1 24.3 82.4 32.3 19.9 11.2 26.6 7.7 70.6 7.2 45.3 11.8 23.7 19.5 50.8 115.7 51.7 9.4 41.3 152.2 37.4 47.8 79.0 40.8 555.1 18.1 9.3 29.9 30.5 51.9 48.7 40.3 18.6 19.8 22.5 16.2 46.0 19.2 31.9 4.3 6.3 21.7 22.6 236.6 195.0 141.6 32.7 52.8 CCNO "CCNU, FLJ22422, UDG2, UNG2" ENSG00000152669 "Cyclin O" P22674 5 55231152-55233608 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation" Cyclin "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.3;pancreas: 10.1;testis: 13.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.3;Club cells: 51.4;Collecting duct cells: 33.1;Endometrial ciliated cells: 38.1;Ionocytes: 61.1;Respiratory ciliated cells: 97.2;Spermatocytes: 53.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 5.2;T-47d: 7.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA050090 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA050090: AB_2681011" "unprognostic (3.44e-2)" "unprognostic (5.20e-2)" "unprognostic (5.28e-2)" "prognostic favorable (6.78e-4)" "unprognostic (3.96e-2)" "unprognostic (2.60e-1)" "unprognostic (3.18e-3)" "prognostic favorable (7.60e-4)" "unprognostic (3.54e-2)" "unprognostic (2.10e-1)" "unprognostic (1.92e-1)" "unprognostic (3.09e-1)" "unprognostic (3.03e-2)" "prognostic favorable (5.10e-4)" "unprognostic (1.81e-1)" "unprognostic (9.49e-2)" "unprognostic (8.88e-3)" 0.1 0.4 1.3 0.0 2.8 0.0 0.5 1.1 2.3 1.0 12.3 0.3 0.3 0.2 0.3 1.0 2.1 0.1 0.1 2.2 1.8 1.9 0.2 1.3 0.0 1.7 1.9 0.8 10.1 1.1 5.3 0.1 1.1 2.0 0.0 0.1 1.8 1.2 0.0 1.8 0.5 0.0 1.2 0.0 5.6 13.2 2.0 0.0 5.5 0.0 0.0 1.8 0.4 1.3 2.8 3.2 0.0 1.6 0.2 0.0 5.2 0.0 0.0 0.4 0.5 0.0 3.1 0.0 2.0 0.0 1.0 2.6 0.1 0.0 0.0 0.0 4.1 0.1 3.5 0.3 0.0 0.1 0.7 0.0 0.6 0.0 0.0 0.4 0.0 1.3 0.1 0.0 0.0 2.7 0.0 0.1 0.2 0.4 4.4 1.5 0.3 0.0 1.2 1.0 1.9 0.0 3.5 0.8 1.1 0.0 7.5 0.5 0.2 0.0 2.2 2.8 1.2 2.6 1.5 0.0 1.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.8 1.1 2.3 2.2 1.8 1.7 1.9 1.1 1.2 2.0 1.3 0.2 0.0 1.5 0.7 0.0 1.0 3.7 39.3 5.7 11.9 9.2 5.0 0.5 2.8 51.4 33.1 6.2 0.7 0.3 2.7 0.0 4.2 12.5 38.1 0.5 0.3 0.0 0.0 2.8 28.5 1.9 0.6 13.3 5.4 0.0 0.1 0.0 0.0 0.1 1.7 0.3 3.4 61.1 0.0 0.7 4.4 1.2 0.2 1.8 0.0 0.0 0.1 0.0 0.5 0.1 11.1 2.7 0.4 0.0 7.9 5.7 1.0 97.2 0.5 0.0 0.3 5.1 53.9 21.5 3.3 2.4 0.3 0.2 0.0 4.2 5.9 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353744-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in some" "dendritic cells: 40.4;Kupffer cells: 43.1;Macrophages: 25.2;monocytes: 34.9;Plasma cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 560.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 185.5;THP-1: 89.8;U-266/70: 416.5;U-266/84: 177.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.4" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" 2.6 1.9 0.1 25.9 0.1 1.9 3.1 0.1 0.2 1.6 0.3 4.6 7.5 1.2 0.9 1.2 1.2 3.4 1.1 0.1 0.1 1.2 2.1 5.8 11.6 0.4 0.2 1.1 0.8 0.3 0.2 0.8 0.2 1.2 5.1 0.0 3.1 1.7 0.5 1.9 5.7 7.1 0.3 20.4 5.2 1.0 0.2 4.3 1.1 0.5 7.2 5.5 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 2.7 0.0 185.5 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 89.8 0.0 0.0 0.0 0.0 0.3 416.5 177.7 0.0 0.1 3.3 0.1 560.9 146.2 2.6 11.9 12.8 89.2 7.9 24.3 20.2 145.2 1.8 0.6 0.7 3.8 14.0 0.4 113.6 11.4 81.6 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.2 0.3 0.2 0.3 0.1 0.0 1.3 0.0 5.8 0.3 0.0 0.0 0.6 0.0 0.1 0.1 0.3 1.5 0.0 0.0 0.0 0.1 40.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 4.4 0.0 0.0 0.0 0.4 1.1 0.1 0.0 0.0 1.8 0.9 0.8 0.0 0.0 0.0 0.0 43.1 10.5 0.7 0.0 25.2 0.0 0.0 34.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 8.2 0.1 0.1 0.0 CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0;urinary bladder: 5.4" "Cell type enhanced" "Detected in some" "granulocytes: 2.5;Horizontal cells: 5.0;Plasma cells: 2.1;Spermatogonia: 1.8;T-cells: 7.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.9" "Lineage enriched" "Detected in many" 41 "T-cells: 60.9" "Cell line enriched" "Detected in some" 17 "HDLM-2: 206.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" 0.5 0.2 0.3 8.6 0.3 1.7 0.6 0.8 0.7 0.6 0.2 0.9 0.6 0.4 0.3 1.2 0.2 3.3 0.2 0.4 0.4 0.3 0.6 1.7 7.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 0.8 1.2 0.1 0.5 0.1 2.0 2.1 1.5 0.6 0.0 3.2 1.4 0.8 0.2 13.0 0.3 0.1 8.0 5.4 0.2 0.7 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 206.5 0.0 12.2 0.7 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.0 5.8 3.2 0.8 0.0 0.0 1.8 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.5 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.2 0.1 0.2 0.2 0.2 0.0 1.4 0.3 0.3 0.4 0.3 0.4 0.3 11.5 3.4 0.1 0.4 0.3 0.3 1.1 0.3 0.3 0.4 60.9 1.7 0.3 0.3 0.8 0.7 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.7 0.1 0.0 0.6 0.0 0.4 0.4 0.7 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.5 0.0 0.4 0.1 0.1 5.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.7 0.8 0.0 0.5 0.2 0.0 1.8 0.0 0.1 0.0 7.8 0.0 0.0 0.6 CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.0;Erythroid cells: 26.5;Hofbauer cells: 42.7;Kupffer cells: 22.1;Langerhans cells: 36.5;Macrophages: 56.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 21.0;OE19: 8.4;PC-3: 15.3;RT4: 8.3;TIME: 15.4;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" 11.7 1.6 2.1 11.4 2.1 9.0 8.4 2.2 3.7 2.3 2.2 11.5 11.7 1.2 0.6 0.9 1.1 5.5 2.7 2.1 2.2 2.2 4.4 12.4 4.9 2.8 2.3 0.5 1.5 0.8 0.8 5.1 3.1 0.8 10.4 0.2 0.9 0.8 1.1 0.7 12.1 2.5 2.6 8.5 5.5 0.3 2.9 7.7 1.3 1.1 3.8 6.0 1.1 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.2 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.7 4.6 0.0 21.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 5.0 0.2 0.0 7.2 4.2 2.8 0.1 5.0 0.0 1.6 2.6 0.0 8.4 15.3 0.4 0.3 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 15.4 0.6 0.3 0.7 0.3 0.0 8.6 0.2 7.5 6.5 0.0 8.7 15.4 4.3 2.8 22.1 3.4 1.7 1.6 4.7 9.9 3.9 1.0 2.5 2.6 6.7 10.1 3.0 4.7 5.0 2.1 2.1 2.2 3.7 2.1 2.2 2.8 2.3 3.1 2.6 2.9 3.3 35.0 0.0 4.7 0.0 4.4 2.0 0.2 0.2 0.0 0.0 0.4 0.4 1.1 1.5 1.2 0.0 0.0 0.3 4.5 19.5 0.0 0.6 0.1 0.1 0.2 12.1 0.0 26.5 0.0 8.8 1.2 1.4 4.6 0.1 9.5 0.1 6.4 0.4 42.7 0.0 0.0 16.6 0.0 22.1 36.5 0.0 0.0 56.2 1.8 1.9 6.7 0.0 0.0 0.0 0.0 9.8 12.4 0.0 4.2 0.2 17.2 0.2 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 1.1 2.5 6.4 0.4 9.2 1.1 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD200 "MOX1, MOX2, MRC, OX-2" ENSG00000091972 "CD200 molecule" P41217 3 112332347-112362812 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 97.4;Excitatory neurons: 54.5;Inhibitory neurons: 55.7;Syncytiotrophoblasts: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 30.7;naive B-cell: 83.6" "Lineage enriched" "Detected in many" 23 "B-cells: 83.6" "Cell line enhanced" "Detected in some" "AF22: 75.9;HHSteC: 27.2;NTERA-2: 47.7;REH: 42.4;SK-MEL-30: 29.8;WM-115: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031149 Approved NA NA 26000 "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA031149: AB_10600694" "unprognostic (1.84e-1)" "unprognostic (5.08e-2)" "unprognostic (1.79e-1)" "unprognostic (2.03e-3)" "unprognostic (4.97e-1)" "unprognostic (1.21e-2)" "unprognostic (9.29e-2)" "unprognostic (2.25e-2)" "unprognostic (3.06e-1)" "unprognostic (3.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.06e-2)" "unprognostic (2.80e-1)" "unprognostic (4.49e-2)" "unprognostic (1.22e-2)" 25.3 12.1 27.7 15.6 27.3 2.4 11.6 13.2 34.0 20.1 2.9 6.7 3.3 28.4 7.1 8.9 26.7 13.1 9.3 27.9 41.3 8.5 1.0 9.6 26.1 11.9 16.3 11.6 4.9 10.5 26.8 28.2 18.8 12.1 8.2 15.1 9.0 16.5 1.8 4.4 6.9 18.3 15.1 6.2 5.2 2.9 30.4 23.6 18.9 3.6 24.9 27.5 5.9 18.3 0.0 0.0 75.9 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.1 0.2 4.1 0.0 0.9 0.1 8.2 0.4 0.2 0.2 0.5 0.0 0.3 0.4 27.2 0.0 0.1 0.5 0.2 1.6 0.2 0.2 10.8 0.0 0.1 0.7 0.2 0.0 1.2 0.0 47.7 0.0 0.0 42.4 0.1 0.5 0.6 0.1 19.9 23.0 0.0 0.4 29.8 14.0 0.0 0.3 0.1 0.3 2.6 0.0 0.2 0.1 0.1 0.0 0.6 0.2 83.7 3.6 0.4 0.3 0.3 0.1 3.5 30.7 2.0 0.6 1.3 83.6 2.1 1.3 1.7 1.6 0.3 2.8 1.0 3.4 27.7 27.3 13.2 34.0 27.9 41.3 11.9 16.3 18.8 15.1 30.4 18.3 15.2 3.2 9.1 10.7 27.8 4.2 12.6 0.3 0.0 26.8 0.7 13.0 0.8 1.5 1.3 1.8 0.0 3.0 1.6 0.8 0.0 0.3 25.1 20.6 4.2 97.4 38.4 0.8 54.5 0.0 12.1 13.0 3.1 41.0 2.5 0.7 1.4 0.0 1.0 3.3 55.7 8.1 0.0 0.3 6.1 30.3 0.3 1.1 8.8 6.5 14.0 7.1 0.0 29.7 38.5 0.2 10.7 0.0 1.9 15.4 0.9 0.3 2.7 2.5 0.0 13.1 2.6 0.6 0.4 0.7 3.3 75.9 2.9 9.3 7.1 21.6 CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.2;placenta: 22.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 15.6;Langerhans cells: 14.7;Macrophages: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 4 "dendritic cells: 1.2;monocytes: 1.4" "Cell line enriched" "Detected in single" 14 "THP-1: 3.3" "CAB032436, CAB033831" Supported "Intracellular and membrane" NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" 34.2 3.9 0.3 8.6 0.6 0.4 4.4 1.3 3.0 4.0 5.7 10.5 14.3 1.4 1.0 4.8 2.5 8.6 4.5 0.3 0.7 2.1 3.3 4.9 18.1 1.0 0.6 1.0 1.0 0.8 0.7 22.8 0.8 0.8 13.9 0.1 2.1 1.9 0.9 1.4 19.3 10.6 0.9 2.4 4.1 2.1 0.6 5.4 1.4 1.5 2.3 20.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.4 0.3 0.6 1.3 3.0 0.3 0.7 1.0 0.6 0.8 0.9 0.6 0.8 0.3 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 15.6 14.7 0.3 0.0 12.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.1 CD244 "2B4, NAIL, NKR2B4, Nmrk, SLAMF4" ENSG00000122223 "CD244 molecule" Q9BZW8 1 160830160-160862887 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 16.8" "Cell type enhanced" "Detected in some" "dendritic cells: 28.4;Kupffer cells: 17.7;NK-cells: 66.9;T-cells: 21.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 472.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 472.1" "Cell line enhanced" "Detected in some" "HEL: 20.6;HMC-1: 69.4;NB-4: 14.4;U-937: 28.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 280000 "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.11e-3)" "unprognostic (1.54e-2)" "unprognostic (1.85e-2)" "unprognostic (6.95e-6)" "unprognostic (5.79e-2)" "unprognostic (1.43e-4)" "unprognostic (1.93e-2)" "unprognostic (7.36e-2)" "unprognostic (3.36e-1)" "unprognostic (2.85e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-1)" "unprognostic (5.40e-4)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (1.87e-1)" "unprognostic (1.79e-1)" 2.1 0.4 0.3 3.7 0.4 10.0 0.4 0.3 0.5 0.3 0.3 1.1 3.0 0.3 0.3 0.4 0.5 1.0 0.6 0.4 0.3 0.3 4.2 3.3 3.4 0.4 0.3 1.0 0.1 0.1 0.1 0.4 0.3 0.4 1.4 0.0 1.1 0.4 0.3 0.3 2.8 1.1 0.3 16.8 1.0 2.7 0.3 2.8 0.2 0.2 2.0 1.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.4 6.8 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 2.1 14.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 2.6 1.1 0.1 0.0 28.7 0.0 472.1 43.3 107.9 71.3 59.1 35.2 0.3 3.7 39.7 41.0 0.2 5.3 36.0 3.1 78.5 73.6 2.4 0.2 70.7 0.3 0.4 0.3 0.5 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.4 0.1 3.2 6.1 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.0 5.2 0.0 0.1 0.2 0.0 2.1 0.7 1.7 0.0 0.3 0.5 0.1 3.8 0.0 0.7 0.2 0.6 0.0 0.1 0.0 0.0 17.7 3.1 2.4 1.8 8.3 0.0 0.0 8.5 0.0 66.9 0.0 0.2 0.0 0.0 2.2 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.0 0.1 0.0 21.9 0.5 0.0 0.0 CD247 "CD3H, CD3Q, CD3Z" ENSG00000198821 "CD247 molecule" P20963 1 167430640-167518610 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 49.0;lymphoid tissue: 179.4" "Group enriched" "Detected in many" 9 "dendritic cells: 492.1;NK-cells: 727.1;T-cells: 247.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "gdT-cell: 376.4;MAIT T-cell: 208.9;memory CD4 T-cell: 190.0;memory CD8 T-cell: 219.7;naive CD4 T-cell: 237.8;naive CD8 T-cell: 195.1;NK-cell: 225.3;T-reg: 254.5" "Group enriched" "Detected in all" 32 "NK-cells: 225.3;T-cells: 376.4" "Group enriched" "Detected in some" 25 "HDLM-2: 155.9;JURKAT: 113.1;MOLT-4: 167.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" 3.2 1.7 2.3 25.3 2.3 49.0 1.9 2.2 2.5 1.9 1.9 4.3 7.1 2.3 3.1 2.1 1.8 5.5 1.3 2.3 2.3 2.0 5.4 10.9 57.7 2.3 2.2 0.8 0.8 0.5 0.8 1.4 2.2 1.8 4.6 0.2 2.4 1.6 1.4 1.1 14.3 1.5 2.1 40.2 7.0 0.4 2.9 179.4 2.5 0.9 36.4 7.3 1.9 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 155.9 0.3 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.1 0.0 0.1 0.0 0.0 167.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 8.3 1.0 0.4 376.4 1.4 208.9 9.3 190.0 219.7 1.5 4.9 237.8 195.1 8.7 225.3 1.2 2.8 254.5 231.2 2.3 2.3 2.2 2.5 2.3 2.3 2.3 2.2 2.2 2.1 2.9 2.5 3.4 3.2 16.0 3.3 8.2 1.5 0.1 0.0 0.6 0.4 3.5 3.2 0.6 1.5 1.3 0.0 0.0 0.1 492.1 0.4 0.0 0.5 0.2 0.7 0.8 1.8 0.0 14.7 8.8 0.0 0.1 2.2 6.1 1.1 6.3 0.4 7.1 1.4 0.3 3.3 9.4 0.5 0.0 7.8 1.4 0.2 0.0 5.9 3.6 14.0 7.6 0.1 727.1 0.5 3.7 0.0 1.2 0.0 51.9 0.1 0.2 1.3 2.2 0.2 0.0 0.9 1.2 0.1 2.5 1.4 0.6 0.1 247.2 0.0 0.1 0.1 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD27 "S152, TNFRSF7, Tp55" ENSG00000139193 "CD27 molecule" P26842 12 6444955-6451718 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 147.8" "Group enriched" "Detected in many" 11 "B-cells: 119.4;Melanocytes: 97.8;Plasma cells: 352.1;T-cells: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in all" "T-reg: 640.4" "Group enriched" "Detected in all" 7 "B-cells: 293.4;T-cells: 640.4" "Group enriched" "Detected in some" 107 "Daudi: 238.2;U-698: 141.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002420, HPA038936" Enhanced NA NA 100000 "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB002420: AB_563539, HPA038936: AB_2676278" "unprognostic (2.75e-3)" "prognostic favorable (3.77e-5)" "unprognostic (8.87e-3)" "prognostic favorable (2.90e-4)" "unprognostic (2.35e-1)" "prognostic favorable (6.65e-7)" "unprognostic (3.56e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.50e-4)" "unprognostic (1.31e-3)" "unprognostic (4.32e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (2.80e-1)" "unprognostic (3.15e-1)" "unprognostic (1.28e-1)" "unprognostic (7.35e-2)" 2.1 2.6 0.3 59.0 0.5 10.6 4.3 0.0 0.5 2.4 0.1 18.0 22.5 1.7 1.0 10.2 1.9 11.0 3.9 0.1 0.1 1.3 2.0 8.2 147.8 0.5 0.2 3.0 1.4 0.0 0.3 0.4 0.8 2.5 11.6 0.4 12.3 1.4 0.6 1.9 34.5 1.6 0.2 73.8 16.6 0.9 0.4 44.7 6.5 0.7 106.3 19.0 1.4 1.0 0.2 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 238.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.5 0.8 0.0 0.0 1.7 0.0 0.7 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.5 0.1 0.0 0.0 0.0 141.7 0.3 0.1 0.0 6.2 1.6 1.4 117.2 1.3 201.2 293.4 283.5 262.6 1.0 114.8 382.8 281.1 6.2 65.0 1.6 2.4 640.4 182.4 0.3 0.5 0.0 0.5 0.1 0.1 0.5 0.2 0.8 0.2 0.4 1.0 1.1 0.0 4.9 0.3 119.4 2.3 0.1 0.0 0.6 1.1 1.1 1.3 0.1 0.0 0.6 0.0 0.0 0.1 7.0 0.3 0.0 0.2 0.0 0.2 0.3 0.9 1.2 8.4 0.2 0.0 0.0 1.5 3.1 0.3 1.3 0.0 2.5 1.5 0.3 0.0 0.3 0.1 0.0 3.2 4.4 0.3 0.3 3.0 97.8 0.0 5.7 0.4 14.4 1.0 1.0 0.0 0.1 0.4 352.1 0.2 0.0 0.9 0.8 1.4 0.0 0.7 1.3 0.1 0.1 0.6 3.1 0.3 109.5 0.0 2.4 0.0 CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 215.6;Hofbauer cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 175.0;U-2197: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" 24.1 19.1 6.6 12.9 4.3 0.7 15.3 0.4 6.5 22.2 15.6 11.4 11.0 20.2 4.3 5.8 10.0 18.2 14.8 4.2 5.7 5.4 11.8 11.6 3.6 5.9 6.7 13.4 15.3 4.3 6.1 26.2 4.1 16.7 4.2 4.6 15.0 9.6 5.0 16.2 8.4 10.8 2.4 9.0 10.9 6.0 7.5 1.6 8.5 2.2 1.6 14.6 13.0 6.7 43.7 44.6 32.5 82.8 57.7 35.0 102.8 47.5 42.0 33.4 30.4 85.3 90.1 0.6 77.7 39.5 64.1 175.0 31.7 39.9 4.4 30.6 76.3 2.8 47.6 47.1 20.9 0.7 51.8 32.7 17.9 28.3 15.4 19.7 38.7 0.0 15.0 0.8 6.2 66.0 0.3 2.3 84.9 8.6 35.9 0.5 47.9 7.0 27.9 53.8 24.9 59.5 40.1 21.2 88.0 23.0 38.1 26.4 49.8 68.6 60.0 231.6 52.5 0.9 0.8 0.8 114.8 3.4 49.4 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 6.6 4.3 0.4 6.5 4.2 5.7 5.9 6.7 4.1 2.4 7.5 6.7 4.4 19.2 8.1 6.5 1.2 15.0 11.5 12.5 8.0 20.2 14.1 11.8 9.1 2.8 17.0 11.0 31.3 11.6 0.2 6.7 1.9 48.6 0.9 14.4 26.7 22.0 9.0 0.0 18.4 19.0 215.6 43.7 14.3 31.6 14.7 41.4 4.6 14.6 82.5 10.1 12.9 13.1 4.1 8.8 30.8 2.2 9.9 14.7 24.9 7.5 4.2 8.4 0.0 5.5 1.7 24.7 15.1 17.3 1.7 12.1 3.1 2.7 5.8 27.5 13.1 7.0 32.1 1.8 4.9 3.4 10.2 12.3 1.4 8.4 10.6 8.4 CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 30.8;placenta: 14.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 34.1;T-cells: 52.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 101.9" "Lineage enriched" "Detected in many" 7 "T-cells: 101.9" "Group enriched" "Detected in some" 14 "Karpas-707: 360.6;RPMI-8226: 173.2;U-266/70: 294.1;U-266/84: 283.7" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Not detected" "Not detected" HPA070003 Enhanced NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" 4.0 0.3 0.0 14.9 0.1 3.3 0.8 0.1 0.1 1.1 0.9 1.7 1.1 0.7 0.3 0.9 0.5 4.1 0.6 0.1 0.1 0.5 1.3 1.9 28.0 0.1 0.0 0.3 0.5 0.2 0.1 14.8 0.1 1.0 1.9 0.1 0.6 0.8 0.3 0.3 3.0 1.4 0.1 7.2 2.5 0.7 0.2 30.8 0.5 0.1 18.6 4.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.7 2.0 0.0 360.6 0.2 0.0 19.9 0.0 0.1 0.0 0.0 0.1 0.3 173.2 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.3 294.1 283.7 2.9 0.3 0.1 0.0 1.7 0.6 1.0 8.3 0.5 50.6 0.3 54.5 26.1 0.1 0.3 48.1 18.6 13.8 0.2 0.5 0.2 101.9 14.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.5 0.0 1.3 0.0 2.4 2.9 0.1 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 3.2 0.1 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.3 1.0 2.0 0.1 1.3 0.0 0.0 0.1 34.1 0.0 0.0 0.0 0.0 0.8 5.3 0.2 0.0 4.4 0.0 1.0 1.5 0.0 2.1 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.2 1.6 0.1 52.6 0.0 0.0 0.0 CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lung: 8.4;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 5 "granulocytes: 15.2;Hofbauer cells: 32.1;Kupffer cells: 26.3;Langerhans cells: 15.3;Macrophages: 36.1;monocytes: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.3;non-classical monocyte: 242.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.1;HMC-1: 33.1;THP-1: 6.5;U-937: 16.2" "Low region specificity" "Detected in some" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: AB_1846293, HPA060349: " "unprognostic (1.55e-2)" "unprognostic (2.60e-1)" "unprognostic (9.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.68e-2)" "unprognostic (7.51e-2)" "unprognostic (6.51e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-3)" "unprognostic (6.27e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" 4.0 1.3 0.7 6.8 1.1 9.7 0.8 0.8 5.5 0.6 1.1 1.3 1.1 0.6 0.1 0.6 0.7 2.0 0.9 0.7 1.4 0.7 1.5 8.4 2.1 1.7 1.8 0.3 0.6 0.4 0.4 2.9 2.1 0.5 1.3 0.0 0.7 0.5 0.3 0.4 1.2 3.1 1.4 7.3 0.7 0.3 2.7 1.0 1.0 0.2 1.1 3.8 0.4 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 3.3 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.6 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 16.2 0.0 51.8 142.1 7.0 0.7 228.3 0.4 2.7 0.3 0.3 158.8 2.4 0.2 0.2 5.2 43.9 242.7 10.5 0.2 64.6 0.7 1.1 0.8 5.5 0.7 1.4 1.7 1.8 2.1 1.4 2.7 2.2 0.1 0.0 1.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.7 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 15.2 0.0 0.0 0.2 32.1 0.0 0.0 0.0 0.0 26.3 15.3 0.1 0.0 36.1 1.8 1.0 19.6 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 1.3 0.0 0.0 0.0 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 298.7;Endothelial cells: 292.4;Fibroblasts: 121.9;Hepatic stellate cells: 136.0;Leydig cells: 146.3;Peritubular cells: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 64.3;MOLT-4: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" 202.7 28.5 29.2 13.9 28.8 5.7 122.3 27.3 34.2 95.4 21.0 54.2 13.5 71.6 42.3 28.9 82.8 54.3 153.2 25.1 27.5 49.4 5.6 69.1 18.1 29.8 29.5 35.4 18.9 21.8 10.1 219.5 30.8 36.2 19.3 2.3 37.4 33.2 58.5 67.5 39.3 75.5 24.8 21.7 34.4 20.2 32.9 19.0 79.5 68.2 17.1 74.0 61.6 28.0 0.0 0.0 0.2 0.0 3.2 0.3 0.2 0.4 2.4 0.7 1.7 0.0 0.0 0.0 6.2 0.7 0.2 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.7 64.3 1.1 0.0 0.0 1.7 0.0 66.5 0.3 0.5 0.0 0.0 0.1 3.7 0.0 0.3 0.0 0.1 0.2 0.0 0.6 0.1 0.4 2.3 0.0 9.9 0.2 2.8 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 29.2 28.8 27.3 34.2 25.1 27.5 29.8 29.5 30.8 24.8 32.9 28.0 298.7 3.2 7.8 1.6 1.0 16.7 0.2 0.3 4.6 0.6 2.1 3.0 21.9 2.8 0.1 3.7 2.1 0.2 1.5 0.0 0.0 0.5 11.6 1.0 5.2 292.4 0.0 22.3 0.2 0.2 0.3 121.9 0.5 1.0 1.3 0.1 136.0 0.6 0.4 0.0 0.1 0.0 0.0 1.2 21.8 5.0 146.3 2.4 17.8 33.7 0.3 0.2 0.0 0.5 0.3 0.2 0.0 123.0 1.6 0.3 0.0 0.1 0.0 0.2 6.6 7.7 15.2 1.0 2.0 1.5 12.9 0.1 2.2 4.0 0.0 0.3 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD3D T3D ENSG00000167286 "CD3d molecule" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lymphoid tissue: 906.7" "Group enriched" "Detected in many" 14 "dendritic cells: 231.0;T-cells: 665.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 52 "gdT-cell: 1462.4;MAIT T-cell: 990.0;memory CD4 T-cell: 1206.1;memory CD8 T-cell: 1368.7;naive CD4 T-cell: 1091.4;naive CD8 T-cell: 1338.9;T-reg: 1660.4" "Lineage enriched" "Detected in all" 66 "T-cells: 1660.4" "Group enriched" "Detected in some" 4 "JURKAT: 621.5;MOLT-4: 1299.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" 4.1 3.8 0.3 77.5 0.4 28.6 9.9 0.4 1.4 5.2 0.7 18.8 21.7 3.6 5.7 7.6 4.5 15.7 3.7 0.3 0.6 2.3 7.9 20.6 222.7 1.1 0.4 3.2 1.3 0.9 0.8 1.2 0.6 5.9 22.4 0.3 8.3 3.1 2.5 4.0 30.1 3.9 0.7 60.9 23.8 2.4 0.5 906.7 3.8 1.4 166.9 26.7 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 621.5 49.8 0.0 0.0 0.0 1299.8 237.2 1.2 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.2 0.8 0.0 0.5 0.0 1.5 1.1 0.0 0.9 1.1 0.4 0.0 0.1 0.0 10.1 5.3 4.6 1462.4 3.3 990.0 9.6 1206.1 1368.7 5.0 3.7 1091.4 1338.9 25.1 4.2 5.3 6.0 1660.4 1138.7 0.3 0.4 0.4 1.4 0.3 0.6 1.1 0.4 0.6 0.7 0.5 0.8 5.9 6.4 29.6 0.0 18.6 15.3 0.3 0.0 1.8 0.0 5.4 6.7 2.8 7.2 2.6 3.7 0.0 0.4 231.0 0.9 0.0 1.3 0.4 0.8 0.8 5.0 1.2 16.8 0.0 0.0 0.0 8.3 21.4 0.9 12.6 0.0 7.9 3.1 0.6 0.0 0.0 0.2 0.0 14.9 28.4 0.7 0.0 14.2 12.4 1.0 25.0 0.0 32.0 0.0 0.0 0.1 0.2 0.0 21.0 0.3 0.0 3.4 1.5 0.0 0.0 2.5 5.8 0.1 1.2 1.4 11.8 0.3 665.7 0.0 1.1 0.2 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 336.1;dendritic cells: 251.2;Kupffer cells: 245.8;Macrophages: 218.3;monocytes: 366.6;NK-cells: 454.2;T-cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 220.9;HMC-1: 236.9;U-266/70: 501.4;U-266/84: 360.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" 11.8 5.9 1.4 115.3 1.5 148.4 18.8 1.5 4.7 10.2 2.3 24.9 20.5 6.7 5.0 8.4 5.7 26.6 4.3 1.3 1.7 4.4 19.9 31.0 283.9 2.6 1.8 3.1 2.0 1.6 1.6 5.8 2.7 8.1 32.5 0.1 14.0 4.4 2.9 3.5 48.3 12.5 2.1 160.0 32.5 2.9 3.2 138.9 5.2 3.4 256.8 41.8 4.5 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 220.9 0.1 0.0 0.0 0.5 0.1 0.0 0.0 6.0 0.0 2.1 0.0 0.0 0.0 27.1 236.9 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.4 78.6 0.0 0.0 78.9 38.4 0.1 0.0 0.0 4.7 0.1 34.3 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.3 0.2 0.4 501.4 360.3 89.9 0.2 66.7 0.1 218.1 327.1 230.8 242.8 470.2 335.8 206.2 275.2 283.4 329.7 161.2 277.9 301.6 82.1 160.7 487.4 57.0 229.9 603.5 1.4 1.5 1.5 4.7 1.3 1.7 2.6 1.8 2.7 2.1 3.2 4.1 3.7 0.0 9.6 0.7 336.1 5.5 0.8 0.0 1.8 0.0 2.0 1.7 1.1 2.8 1.3 3.7 0.0 0.6 251.2 0.1 1.9 0.2 0.1 0.7 0.5 2.8 1.2 21.5 0.1 0.2 0.8 2.4 6.6 0.6 90.7 0.1 7.1 2.0 86.4 0.0 0.1 0.1 0.0 245.8 106.5 0.5 1.8 218.3 39.2 1.0 366.6 0.0 454.2 0.5 0.0 0.1 0.0 0.4 127.4 0.4 0.0 4.9 2.2 0.0 0.0 1.7 2.1 0.5 0.3 0.7 3.0 0.4 376.2 0.0 1.2 0.5 CD5 "LEU1, T1" ENSG00000110448 "CD5 molecule" P06127 11 61102489-61127852 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 46.5" "Cell type enhanced" "Detected in some" "dendritic cells: 7.5;Langerhans cells: 9.3;Muller glia cells: 16.0;T-cells: 57.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 138.2" "Lineage enriched" "Detected in many" 33 "T-cells: 138.2" "Group enriched" "Detected in some" 66 "JURKAT: 21.0;MOLT-4: 70.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB015392, CAB020308, HPA043416, HPA060839" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB015392: AB_2075324, CAB020308: , HPA043416: AB_2678472, HPA060839: AB_2684376" "prognostic favorable (4.05e-4)" "prognostic favorable (9.16e-5)" "unprognostic (2.33e-1)" "prognostic favorable (9.00e-5)" "unprognostic (1.02e-2)" "prognostic favorable (7.41e-6)" "unprognostic (2.45e-3)" "unprognostic (1.37e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.94e-5)" "unprognostic (4.78e-2)" "unprognostic (1.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.06e-1)" 1.4 0.9 0.4 22.6 0.4 12.2 1.0 0.1 0.5 0.9 0.0 2.8 3.1 0.7 0.4 2.3 0.8 4.9 0.9 0.6 0.4 0.8 1.5 5.7 38.0 0.2 0.0 0.8 0.4 0.2 0.4 0.3 0.5 1.0 2.7 1.8 6.4 0.3 0.6 1.4 7.1 1.2 0.0 14.1 7.9 0.8 0.3 46.5 1.0 0.3 22.2 6.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.1 70.5 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.6 45.9 0.4 32.8 1.5 108.7 72.5 3.7 3.4 88.4 69.8 1.8 0.4 3.4 4.1 138.2 61.5 0.4 0.4 0.1 0.5 0.6 0.4 0.2 0.0 0.5 0.0 0.3 0.0 0.4 0.0 1.7 0.0 4.1 0.9 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 2.7 0.0 0.1 0.2 0.0 1.3 0.3 0.0 0.0 0.9 2.6 0.1 1.3 0.0 1.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 9.3 0.9 0.0 1.8 3.6 0.0 2.1 16.0 1.0 0.0 0.1 0.1 0.3 0.0 6.3 0.0 0.0 0.1 0.0 1.3 0.0 0.1 0.6 0.4 0.7 0.2 0.3 0.0 57.0 0.0 0.2 0.2 CD52 "CDW52, EDDM5, HE5" ENSG00000169442 "CD52 molecule" P31358 1 26317958-26320523 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "epididymis: 36173.0" "Cell type enhanced" "Detected in many" "B-cells: 1861.9;granulocytes: 568.6;Hofbauer cells: 562.6;Langerhans cells: 674.3;Macrophages: 690.5;monocytes: 814.2;NK-cells: 602.5;T-cells: 1300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Daudi: 708.6;REH: 1042.2;U-266/84: 1087.0;U-698: 1159.2" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "prognostic favorable (1.85e-5)" "unprognostic (3.28e-3)" "unprognostic (1.93e-2)" "prognostic favorable (2.06e-4)" "unprognostic (4.18e-2)" "prognostic favorable (4.45e-4)" "unprognostic (9.11e-2)" "unprognostic (2.98e-2)" "unprognostic (7.73e-3)" "unprognostic (6.27e-2)" "unprognostic (4.58e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.64e-1)" "unprognostic (6.14e-2)" "unprognostic (7.95e-2)" "unprognostic (1.26e-1)" 62.1 10.2 10.2 297.8 13.5 266.9 59.5 9.6 38.5 26.1 12.6 68.6 41.7 21.3 36173.0 35.0 18.4 89.2 18.0 10.3 10.0 18.7 55.0 449.2 1082.0 11.3 10.0 9.6 8.2 5.4 6.1 16.9 10.5 19.2 96.9 0.2 37.6 104.2 9.4 27.9 294.7 47.4 10.1 646.5 87.2 4.7 16.5 1051.6 24.9 13.8 1256.4 134.9 13.1 10.5 2.0 0.0 0.3 0.0 0.0 1.4 14.3 0.1 1.0 0.1 0.0 0.3 0.6 708.6 1.4 0.0 0.3 0.1 0.0 0.2 0.0 0.5 0.2 34.8 0.0 1.4 0.0 7.5 106.4 0.0 0.0 0.2 0.0 0.7 0.0 44.9 23.7 1.0 0.0 4.6 8.5 62.9 3.0 0.5 0.0 1042.2 0.9 16.6 0.0 0.0 2.1 9.3 0.4 1.1 1.3 9.2 0.3 12.5 1.6 0.0 2.7 0.7 1.2 2.9 1087.0 1159.2 0.1 17.8 0.1 599.3 4558.9 9769.3 6605.8 7389.3 5319.0 10570.4 8177.1 6530.7 3180.2 10064.7 5495.2 5664.3 334.5 3732.1 6667.9 1034.9 11684.0 22571.2 10.2 13.5 9.6 38.5 10.3 10.0 11.3 10.0 10.5 10.1 16.5 10.5 9.5 67.3 194.6 0.0 1861.9 45.4 0.8 0.2 3.4 0.0 8.4 5.8 6.2 14.3 50.1 49.7 0.0 4.7 415.9 1.9 0.0 1.3 0.8 3.9 2.6 29.5 0.0 60.6 0.3 0.2 5.8 18.1 29.6 7.1 568.6 0.0 17.5 3.6 562.6 0.0 0.1 2.3 0.0 262.6 674.3 1.4 0.0 690.5 106.7 1.9 814.2 0.0 602.5 0.0 0.1 0.2 2.8 0.0 133.7 3.1 0.7 11.5 17.5 0.0 0.0 7.3 9.1 0.3 0.5 3.2 31.4 5.6 1300.0 0.0 2.7 1.1 CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 310.0;dendritic cells: 375.0;Hofbauer cells: 365.7;Kupffer cells: 324.3;Macrophages: 294.8;NK-cells: 383.1;T-cells: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 473.5;HDLM-2: 214.8;HMC-1: 298.4;Karpas-707: 188.1;U-266/70: 251.2;U-698: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" 63.4 30.8 10.1 284.4 11.1 126.6 27.0 12.6 16.3 20.8 12.3 41.5 37.9 17.3 10.5 20.0 22.8 58.5 12.2 9.7 13.4 15.1 46.8 114.9 397.9 18.9 16.0 9.2 11.9 6.6 6.2 58.5 18.9 12.8 54.8 2.0 19.3 12.8 4.5 6.7 103.4 55.8 18.3 269.4 44.3 5.7 17.5 144.9 11.3 10.6 448.3 85.1 9.0 31.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 473.5 0.2 0.0 0.2 0.5 0.0 0.0 0.0 214.8 0.0 26.4 0.1 0.0 0.0 60.4 298.4 0.0 0.0 0.0 0.0 0.0 0.0 139.2 11.2 188.1 0.0 0.0 103.1 71.1 0.4 0.0 0.0 98.0 0.7 104.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 1.5 0.0 88.4 17.2 0.2 0.4 0.1 0.5 251.2 123.2 149.2 1.5 68.7 3.4 1483.0 779.5 479.0 732.4 808.6 658.1 794.0 527.8 649.2 631.9 745.1 377.9 552.5 1144.2 526.6 882.9 517.5 740.3 1621.0 10.1 11.1 12.6 16.3 9.7 13.4 18.9 16.0 18.9 18.3 17.5 31.9 4.2 16.0 24.4 0.7 310.0 7.0 0.6 0.0 0.6 0.0 2.3 5.1 1.0 5.7 8.6 1.8 0.0 2.1 375.0 0.2 0.0 0.5 0.4 0.4 0.5 13.0 0.0 42.9 5.8 0.2 5.4 6.7 7.1 0.6 162.2 0.0 16.4 6.7 365.7 0.0 1.4 0.3 0.0 324.3 161.5 1.9 2.1 294.8 39.2 69.3 156.3 0.1 383.1 1.0 0.6 0.3 0.1 0.4 134.0 0.3 0.0 1.6 4.4 0.6 6.6 1.9 1.8 0.1 0.6 1.1 5.5 4.1 297.0 0.0 0.2 0.3 CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.6;lymphoid tissue: 43.1" "Cell type enhanced" "Detected in many" "dendritic cells: 25.7;NK-cells: 49.4;Plasma cells: 18.5;T-cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 33 "gdT-cell: 27.7;MAIT T-cell: 24.7;memory CD4 T-cell: 51.4;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.4;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 51 "T-cells: 51.4" "Group enriched" "Detected in some" 12 "JURKAT: 10.2;MOLT-4: 39.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" NA NA 5270000 160000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" 1.4 0.9 1.5 21.9 0.9 11.3 1.2 0.5 1.1 1.3 0.7 3.2 4.0 0.9 0.7 1.8 1.4 3.9 0.5 0.6 1.7 1.0 1.4 6.6 43.1 1.5 2.0 0.9 0.6 0.2 0.4 0.3 1.7 1.1 3.1 0.2 3.2 0.4 0.8 1.3 13.6 0.7 0.9 18.0 6.6 0.7 2.5 39.6 1.4 0.3 29.0 4.8 1.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.2 0.0 0.0 0.0 39.2 0.1 0.2 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.4 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.7 0.0 24.7 1.0 51.4 48.4 0.3 0.9 34.4 25.2 0.7 0.2 0.0 0.0 25.5 13.8 1.5 0.9 0.5 1.1 0.6 1.7 1.5 2.0 1.7 0.9 2.5 0.9 3.2 0.0 2.5 0.3 10.8 2.0 0.2 0.1 0.0 1.4 0.9 0.8 2.6 1.5 0.1 0.0 0.0 0.2 25.7 0.2 0.0 0.2 0.9 0.4 0.3 1.2 0.0 0.0 0.8 0.6 0.2 1.5 8.2 0.3 0.0 0.1 2.5 0.8 2.0 1.7 0.9 0.0 0.0 1.9 4.4 0.4 0.3 3.4 3.6 1.0 2.4 0.0 49.4 0.0 0.2 0.7 0.2 0.0 18.5 0.0 0.1 0.2 0.1 0.2 0.0 1.0 0.9 0.4 0.9 1.0 1.4 0.3 107.3 0.7 0.5 0.4 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD69 CLEC2C ENSG00000110848 "CD69 molecule" Q07108 12 9752486-9760901 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 169.1;lymphoid tissue: 94.4" "Cell type enhanced" "Detected in many" "B-cells: 1017.1;dendritic cells: 694.0;granulocytes: 1455.3;Plasma cells: 308.8;T-cells: 1185.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 26.7;T-cells: 30.8" "Cell line enhanced" "Detected in some" "HL-60: 30.0;JURKAT: 19.5;K-562: 58.4;MOLT-4: 20.9;U-266/70: 22.5;U-698: 25.6;U-937: 97.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002503, HPA050525" Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB002503: AB_563625, HPA050525: AB_2681157" "prognostic favorable (3.31e-5)" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "unprognostic (7.10e-3)" "unprognostic (4.76e-3)" "unprognostic (9.53e-3)" "unprognostic (9.73e-3)" "unprognostic (1.64e-2)" "unprognostic (1.96e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.88e-2)" "unprognostic (3.32e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" 14.0 6.2 0.9 48.1 0.7 169.1 18.9 1.2 1.0 9.3 2.2 8.9 8.2 6.0 2.9 11.9 7.7 27.3 3.5 0.7 1.7 4.9 12.9 22.6 94.4 1.7 1.1 2.6 1.7 2.0 4.0 2.6 1.6 10.4 21.3 0.2 5.1 2.9 0.7 4.3 19.5 14.3 2.2 43.6 11.8 1.3 1.0 57.0 6.9 4.6 60.1 18.0 7.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 1.1 0.0 1.5 0.0 0.0 0.0 0.0 12.1 0.0 0.0 1.5 30.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 19.5 58.4 0.0 0.0 0.0 20.9 5.9 0.0 0.0 0.0 0.1 0.0 0.0 0.9 8.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 22.5 2.7 25.6 0.0 97.8 0.0 1.3 0.1 5.9 22.9 0.1 30.8 6.0 14.5 16.9 0.1 6.2 20.6 15.6 0.3 26.7 0.0 0.0 7.9 7.3 0.9 0.7 1.2 1.0 0.7 1.7 1.7 1.1 1.6 2.2 1.0 2.4 13.5 41.7 116.7 0.0 1017.1 18.5 3.8 0.0 10.8 0.1 11.8 14.7 2.0 7.2 5.0 1.8 0.0 0.9 694.0 1.1 0.0 1.1 0.4 5.7 3.6 14.3 0.0 33.7 0.0 0.0 0.3 15.4 63.7 16.7 1455.3 0.0 14.6 2.4 16.6 0.0 0.0 0.2 0.0 15.4 77.1 0.3 0.0 80.1 33.8 10.3 3.2 0.1 57.7 0.0 0.1 0.0 0.1 0.0 308.8 2.2 0.4 2.1 1.5 0.6 0.0 4.3 9.2 0.1 0.3 4.2 18.2 1.9 1185.9 0.0 0.9 3.3 CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.6;lymphoid tissue: 53.7" "Group enriched" "Detected in many" 9 "dendritic cells: 625.0;NK-cells: 1299.7;T-cells: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 231.5" "Group enriched" "Detected in many" 22 "NK-cells: 231.5;T-cells: 71.5" "Cell line enhanced" "Detected in some" "Hep G2: 52.0;JURKAT: 26.7;MOLT-4: 119.2" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002594: , HPA039079: AB_2676337" "unprognostic (3.14e-3)" "prognostic favorable (5.51e-4)" "unprognostic (1.89e-2)" "prognostic favorable (2.03e-5)" "unprognostic (7.69e-3)" "unprognostic (1.09e-3)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "prognostic favorable (2.69e-4)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.75e-11)" "unprognostic (4.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" 8.2 1.3 0.7 32.9 0.8 28.6 2.6 0.8 1.3 2.5 0.9 7.3 12.4 3.0 0.4 3.9 3.9 3.2 1.8 0.6 1.1 7.1 7.7 17.1 36.8 1.4 0.8 0.8 1.2 0.1 1.4 3.3 1.0 4.4 1.9 0.0 3.1 1.0 0.8 1.7 21.1 1.1 1.2 53.7 8.1 0.6 1.1 48.8 3.5 0.1 14.8 3.9 3.9 1.2 0.0 0.0 0.0 0.0 0.1 0.4 12.9 0.0 0.2 0.1 0.2 0.6 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.7 52.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 26.7 0.1 0.0 0.1 0.0 119.2 0.0 0.0 0.0 0.2 0.1 0.1 2.3 0.2 0.0 0.4 0.3 1.8 1.1 0.0 0.3 0.0 0.0 0.0 0.3 0.3 1.0 0.0 1.2 0.2 0.0 0.2 0.0 0.0 0.5 0.4 0.5 66.6 0.2 57.6 0.4 29.8 49.0 0.3 0.2 69.4 71.5 2.3 231.5 0.6 6.9 28.7 30.9 0.7 0.8 0.8 1.3 0.6 1.1 1.4 0.8 1.0 1.2 1.1 1.2 5.3 0.0 0.0 0.0 12.1 7.5 0.6 0.1 1.8 0.0 4.2 3.7 0.5 4.3 0.3 0.0 0.0 0.7 625.0 9.4 0.0 1.3 0.1 2.8 2.0 4.5 0.0 47.7 0.0 0.5 10.3 12.4 43.8 5.3 8.2 0.0 16.8 3.3 3.6 1.7 0.0 1.5 0.0 18.5 8.8 0.0 0.0 19.2 12.4 0.0 11.6 0.0 1299.7 0.0 0.0 0.1 5.8 0.0 82.7 3.8 8.1 1.4 0.5 0.0 0.0 0.5 3.9 0.0 1.3 1.0 4.4 1.9 527.4 0.0 2.1 3.8 CD79A "IGA, MB-1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 152.3;lymphoid tissue: 545.2" "Group enriched" "Detected in some" 5 "B-cells: 1186.4;Plasma cells: 956.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "memory B-cell: 1273.8;naive B-cell: 1457.5" "Lineage enriched" "Detected in all" 40 "B-cells: 1457.5" "Group enriched" "Detected in some" 22 "Daudi: 1598.7;REH: 491.0;U-698: 1366.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000019, HPA056444" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB000019: AB_2244527, HPA056444: " "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" 4.8 4.9 0.2 213.4 0.2 47.2 9.5 0.2 0.4 3.6 0.1 47.3 37.9 2.4 1.4 9.9 1.8 13.0 2.9 0.1 0.1 3.4 2.6 8.9 482.4 0.3 0.2 3.7 0.6 0.1 0.3 1.2 0.2 4.3 28.9 0.0 28.5 2.2 0.7 0.4 152.3 2.2 0.6 286.5 76.9 2.4 0.2 93.7 8.1 0.4 545.2 32.3 1.9 0.3 1.1 0.8 0.3 0.1 0.2 0.7 0.2 0.2 0.0 0.3 0.0 0.0 0.1 1598.7 1.2 0.0 0.1 0.0 0.2 0.2 0.0 0.5 0.7 2.7 0.0 1.7 0.2 2.6 1.8 0.5 0.6 0.2 0.0 0.0 0.0 8.0 3.1 0.4 0.1 1.1 1.6 9.9 0.1 0.1 0.4 491.0 0.8 2.5 0.1 0.0 0.5 0.5 0.8 0.5 1.3 0.0 0.0 4.8 1.6 0.1 4.3 0.3 0.8 7.8 1.4 1366.7 0.0 52.1 0.1 12.4 1.5 6.9 1.7 1.8 0.7 1273.8 4.1 2.1 2.5 1457.5 4.9 26.3 4.6 2.6 4.3 36.3 10.4 62.7 0.2 0.2 0.2 0.4 0.1 0.1 0.3 0.2 0.2 0.6 0.2 0.3 0.2 0.0 2.4 0.0 1186.4 1.8 0.5 0.5 0.6 0.0 0.7 0.9 0.2 1.5 0.2 0.0 0.0 0.2 18.2 0.7 0.0 1.8 0.2 0.1 0.3 0.5 0.0 10.5 0.0 25.6 0.4 2.2 6.6 0.2 0.0 0.4 2.2 1.0 0.8 0.0 0.0 0.4 0.0 4.1 1.4 0.0 0.3 5.3 138.7 0.0 6.3 0.0 15.5 0.0 0.0 181.7 0.4 0.4 956.7 0.3 0.2 0.9 0.0 0.0 0.0 0.2 0.7 0.3 0.6 0.9 1.4 0.1 23.5 0.2 5.3 0.2 CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.2" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Hofbauer cells: 91.1;Kupffer cells: 177.0;Macrophages: 90.6;monocytes: 76.4;T-cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.8;HEL: 45.3;HL-60: 13.1;HMC-1: 49.7;MOLT-4: 12.9;U-698: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" 3.3 2.4 1.9 19.4 2.1 7.9 2.7 2.3 2.4 2.8 1.9 3.2 2.4 1.4 0.9 2.2 1.1 6.2 1.4 1.7 1.9 0.8 5.2 7.8 24.2 5.2 3.1 1.5 2.0 0.9 0.4 7.1 4.5 1.1 4.5 0.2 1.4 3.4 0.4 1.3 4.6 4.0 3.8 15.2 3.6 1.9 5.2 9.9 1.1 0.7 13.2 4.7 0.8 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 45.3 0.1 0.0 0.0 13.1 49.7 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.9 0.1 0.0 0.0 12.9 9.7 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.8 0.0 2.9 0.0 32.7 9.6 15.0 8.2 8.0 6.5 6.3 7.0 10.1 7.1 6.0 4.0 7.4 1.2 1.4 3.2 4.1 10.5 8.8 1.9 2.1 2.3 2.4 1.7 1.9 5.2 3.1 4.5 3.8 5.2 7.2 1.3 0.0 6.4 0.0 27.4 2.4 0.7 0.0 0.6 0.2 0.6 1.5 1.2 2.8 1.3 0.0 0.0 0.5 20.5 0.2 0.0 0.1 0.9 0.5 0.2 4.2 0.0 21.5 0.1 0.2 0.5 1.2 2.6 0.2 187.1 0.1 3.3 1.1 91.1 0.0 0.2 0.1 0.0 177.0 42.2 1.5 0.6 90.6 5.4 34.7 76.4 0.0 4.1 0.0 0.1 0.0 0.0 0.0 10.8 0.9 0.3 0.3 0.7 0.2 0.0 1.6 1.5 0.1 0.4 0.5 2.4 1.0 46.8 2.9 0.2 0.6 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 4 "dendritic cells: 96.8;NK-cells: 58.7;T-cells: 199.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cell line enhanced" "Detected in some" "HEL: 15.9;JURKAT: 18.2;MOLT-4: 68.7;RT4: 58.2;U-937: 59.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" 5.2 1.7 0.7 12.2 0.8 16.0 2.8 1.2 1.0 3.1 1.8 5.0 6.0 2.6 0.9 1.8 1.9 5.8 0.8 0.8 0.8 1.6 3.7 8.3 26.9 1.8 0.7 0.9 0.4 0.2 0.7 1.0 1.2 2.1 5.9 0.1 2.7 1.1 0.4 1.0 10.1 1.4 0.7 12.8 6.8 0.8 1.2 61.8 3.9 0.1 20.2 11.8 2.6 2.2 0.1 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.3 1.6 0.3 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.2 0.0 15.9 0.2 0.2 0.0 0.8 1.3 0.0 0.0 0.1 0.1 1.2 0.0 18.2 0.3 2.0 0.0 0.0 68.7 0.2 0.6 0.0 0.0 0.1 1.9 0.5 0.6 58.2 0.1 0.0 0.2 0.9 0.1 0.3 0.3 0.2 0.0 0.3 1.1 0.3 0.1 5.6 1.9 0.0 0.3 59.0 12.2 2.3 0.5 15.6 74.0 0.3 117.2 10.8 67.0 85.3 0.3 18.8 68.7 81.8 2.7 79.5 0.7 0.5 47.4 46.4 0.7 0.8 1.2 1.0 0.8 0.8 1.8 0.7 1.2 0.7 1.2 2.2 1.5 19.2 19.0 0.0 12.5 3.2 0.8 0.1 1.2 1.6 1.6 1.4 1.0 0.0 9.3 1.8 0.0 0.6 96.8 0.8 0.0 0.1 0.8 2.1 0.8 3.0 0.0 9.3 0.7 0.0 0.2 4.3 8.6 1.6 16.4 0.4 2.2 0.9 0.2 0.0 0.4 0.7 0.0 5.0 6.7 1.1 0.3 6.7 3.6 6.5 2.9 0.5 58.7 0.0 0.1 0.0 1.3 0.0 29.6 0.3 0.0 0.4 1.7 2.1 0.0 0.8 1.0 0.4 0.7 0.6 3.1 1.9 199.9 0.2 0.5 0.6 CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.1;Horizontal cells: 52.2;Inhibitory neurons: 57.2;Oligodendrocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Supported "Plasma membrane" NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA038782: AB_10795139, HPA038783: AB_10794734, HPA061400: AB_2732660" "unprognostic (2.10e-2)" "unprognostic (2.62e-3)" "unprognostic (3.12e-3)" "unprognostic (6.03e-3)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (5.56e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.74e-5)" "unprognostic (5.50e-2)" "unprognostic (5.13e-2)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (9.23e-2)" "prognostic unfavorable (8.74e-4)" 46.1 28.1 68.5 14.8 69.5 7.3 29.7 71.0 99.6 33.4 26.8 40.1 10.0 39.9 24.5 14.5 30.5 19.2 61.6 69.9 80.4 24.9 47.3 25.2 13.2 104.7 77.9 38.9 18.7 14.6 23.8 21.5 107.2 25.8 10.6 43.4 14.8 32.6 179.1 13.4 19.2 32.4 71.5 26.9 21.8 11.2 91.6 14.5 16.8 99.2 10.7 29.4 21.0 80.2 8.1 79.8 29.5 36.9 153.3 95.2 8.7 65.2 76.1 32.3 46.3 5.5 10.2 29.3 154.0 114.6 24.2 13.0 40.4 44.4 26.6 68.5 31.9 12.7 17.8 8.2 41.2 21.4 23.3 90.3 14.5 24.0 45.4 50.3 38.6 22.4 8.9 74.9 41.1 17.3 18.9 31.1 12.4 6.9 42.7 18.8 24.2 40.5 31.7 5.4 38.9 19.9 25.8 21.9 29.6 21.6 6.2 36.6 45.8 47.5 14.4 62.2 48.0 62.6 112.3 28.3 59.6 42.3 36.4 7.3 8.6 5.9 6.2 7.6 5.4 4.5 5.8 6.3 8.1 4.8 5.5 6.0 2.1 7.2 12.5 5.8 4.4 7.0 68.5 69.5 71.0 99.6 69.9 80.4 104.7 77.9 107.2 71.5 91.6 80.2 14.1 16.0 7.8 21.5 8.2 3.1 2.3 3.6 4.6 26.8 3.7 3.2 42.8 11.5 6.4 12.9 18.8 10.1 7.4 2.0 5.9 4.4 0.3 5.6 10.1 13.8 8.4 6.5 49.1 5.3 3.9 15.9 7.1 3.6 7.6 12.6 17.2 26.6 10.2 52.2 57.2 2.9 8.2 16.4 6.8 2.8 20.8 8.6 10.6 23.4 8.1 18.2 2.1 21.6 60.7 3.6 3.1 30.1 12.5 3.4 5.3 11.3 5.0 18.7 0.0 15.9 12.0 2.8 4.9 3.3 1.3 13.5 6.4 11.8 3.3 1.3 CDC42EP2 "BORG1, CEP2" ENSG00000149798 "CDC42 effector protein 2" O14613 11 65314866-65322417 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 50.5;Langerhans cells: 77.7;Pancreatic endocrine cells: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 50.4;intermediate monocyte: 118.8;neutrophil: 171.5;non-classical monocyte: 88.5" "Group enriched" "Detected in many" 15 "granulocytes: 171.5;monocytes: 118.8" "Cell line enhanced" "Detected in many" "HHSteC: 51.5;PC-3: 61.0;U-2197: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038562 Approved Supported Microtubules,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Microtubules, Cytosol" "HPA038562: AB_10671745" "unprognostic (1.69e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (4.73e-3)" "prognostic unfavorable (2.89e-5)" "prognostic unfavorable (6.66e-4)" "unprognostic (1.01e-1)" "unprognostic (5.36e-2)" "unprognostic (8.57e-3)" "unprognostic (3.81e-1)" "unprognostic (1.68e-1)" "unprognostic (2.66e-2)" "unprognostic (3.67e-2)" "unprognostic (2.89e-2)" "unprognostic (1.89e-2)" 42.1 5.7 15.4 7.7 25.1 0.4 23.1 20.7 20.0 13.9 5.8 15.4 9.1 16.6 1.7 7.7 15.3 15.2 22.4 15.7 17.0 15.3 4.1 19.1 1.8 24.9 23.6 10.8 5.8 0.6 5.0 11.6 22.3 10.2 1.6 1.9 4.9 4.5 6.6 5.6 13.0 6.8 17.5 18.4 14.5 2.1 21.4 0.4 16.8 5.6 1.2 18.6 9.4 44.3 7.1 6.6 0.9 4.3 14.6 26.4 1.3 7.4 28.8 5.5 6.2 19.8 16.7 0.5 20.9 19.9 2.0 8.9 2.5 26.0 1.2 1.0 3.8 1.3 12.8 14.8 51.5 0.4 0.5 11.5 2.7 20.3 28.8 4.5 22.4 1.0 2.6 4.3 7.1 10.7 0.8 1.6 3.7 18.5 61.0 0.8 0.7 0.5 19.5 4.9 0.5 1.7 18.0 14.7 1.1 0.7 2.5 0.4 30.6 6.7 5.6 55.9 3.1 0.1 1.7 0.6 11.2 0.3 2.7 0.0 50.4 2.1 0.1 118.8 0.1 1.2 0.0 0.1 9.9 0.0 0.1 0.0 171.5 0.0 88.5 0.4 0.0 17.8 15.4 25.1 20.7 20.0 15.7 17.0 24.9 23.6 22.3 17.5 21.4 44.3 25.8 0.0 0.0 0.0 1.5 12.7 11.0 25.8 6.8 15.3 12.1 6.3 6.3 2.8 17.0 12.9 0.0 0.5 1.6 10.0 3.9 50.5 0.5 6.0 11.6 36.4 1.8 2.7 0.6 40.3 3.5 32.3 9.7 11.1 5.7 1.5 26.7 0.9 1.3 3.3 0.4 8.0 8.2 18.7 77.7 1.9 18.6 33.3 12.4 1.0 18.3 1.0 0.0 0.0 10.6 65.1 15.6 13.5 1.8 7.4 21.2 3.7 6.3 5.3 39.5 16.6 16.2 1.7 3.4 4.8 10.1 1.6 1.4 1.8 8.4 36.4 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDH20 "Cdh7, CDH7L3" ENSG00000101542 "Cadherin 20" Q9HBT6 18 61333430-61555779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 33.7;retina: 11.0;tongue: 24.1" "Group enriched" "Detected in some" 6 "Astrocytes: 1264.4;Oligodendrocyte precursor cells: 742.4;Oligodendrocytes: 1030.7" "Cancer enriched" "Detected in single" 15 "glioma: 6.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 2.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.3" "Cell line enhanced" "Detected in some" "AF22: 1.8;ASC diff: 5.7;HHSteC: 2.6;SH-SY5Y: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015490 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA015490: AB_1845900" "unprognostic (2.15e-1)" "unprognostic (1.66e-2)" "unprognostic (1.42e-2)" "unprognostic (3.68e-3)" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.87e-2)" "unprognostic (1.40e-2)" "unprognostic (1.52e-1)" "unprognostic (3.69e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (3.82e-2)" "unprognostic (1.27e-1)" "unprognostic (3.01e-2)" "unprognostic (1.93e-1)" 4.7 0.1 22.1 0.0 29.9 0.0 0.9 24.8 19.9 0.2 2.3 0.0 0.0 0.1 0.6 0.8 0.2 0.0 0.1 20.0 19.8 0.1 0.0 0.0 0.0 27.5 28.7 0.0 0.1 0.0 1.6 0.0 29.1 0.2 0.0 11.0 0.4 0.0 4.7 0.5 0.2 0.0 21.5 0.1 0.1 0.4 23.1 0.0 0.3 24.1 0.0 0.3 0.0 33.7 0.0 0.0 1.8 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 22.1 29.9 24.8 19.9 20.0 19.8 27.5 28.7 29.1 21.5 23.1 33.7 0.2 0.0 0.0 1264.4 0.1 0.0 0.0 0.0 0.0 26.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 2.6 0.1 0.2 0.2 0.0 0.0 146.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 98.7 0.1 0.0 0.3 0.0 2.7 0.0 0.1 0.0 41.2 0.0 11.1 0.0 742.4 1030.7 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.1 0.0 1.0 0.2 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 15.2;ovary: 6.1" "Group enriched" "Detected in some" 13 "Early spermatids: 27.1;granulocytes: 79.1;Late spermatids: 40.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "Group enriched" "Detected in some" 28 "basophil: 1.8;eosinophil: 3.7" "Lineage enriched" "Detected in single" 37 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "BJ hTERT+: 22.6;BJ hTERT+ SV40 Large T+ RasG12V: 20.7;HBF TERT88: 30.9;HMC-1: 58.4;LHCN-M2: 19.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 0.7 0.3 0.0 0.2 0.0 0.0 0.8 2.4 0.4 0.8 0.0 0.5 0.3 0.6 15.2 0.6 0.5 1.9 0.2 0.5 0.0 0.3 0.0 1.0 0.1 0.4 0.1 6.1 0.1 0.2 0.3 0.0 0.4 0.7 0.7 0.0 0.3 0.3 0.9 0.6 0.8 0.4 0.1 0.0 0.7 1.9 0.1 0.2 0.1 0.7 0.1 0.8 0.5 0.3 0.3 0.0 0.0 0.0 1.6 2.8 0.0 5.9 22.6 10.2 20.7 0.0 3.0 0.0 0.0 2.3 0.5 0.0 0.0 0.0 30.9 0.0 0.1 1.9 0.0 0.0 0.3 0.1 58.4 3.4 0.0 2.7 1.5 0.4 0.0 0.0 0.0 0.1 19.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.5 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.4 0.5 0.0 0.4 0.1 0.4 0.1 0.1 0.3 0.1 0.0 1.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.8 0.0 0.0 79.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 40.3 0.3 0.1 3.6 1.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.5 0.2 0.0 0.1 0.0 0.9 0.1 0.0 0.0 CDKN1A "CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1" ENSG00000124762 "Cyclin dependent kinase inhibitor 1A" P38936 6 36676460-36687337 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 74.5" "Group enriched" "Detected in many" 9 "B-cells: 20.7;dendritic cells: 21.5;monocytes: 74.5" "Cell line enhanced" "Detected in many" "HHSteC: 798.5;HSkMC: 586.5;hTCEpi: 775.8;LHCN-M2: 604.2" "Region enhanced" "Detected in all" "olfactory bulb: 76.0" "Low region specificity" "Detected in all" "CAB000064, HPA005946, CAB069401" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies" "CAB000064: , CAB069401: AB_1620493, HPA005946: AB_2667477" "unprognostic (7.99e-3)" "unprognostic (4.01e-2)" "unprognostic (1.58e-1)" "prognostic favorable (3.14e-5)" "unprognostic (1.57e-2)" "unprognostic (2.19e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.30e-1)" "unprognostic (7.27e-2)" "unprognostic (2.79e-2)" "unprognostic (7.55e-3)" "prognostic favorable (4.95e-5)" "unprognostic (8.32e-2)" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (3.21e-2)" 322.1 98.1 47.0 62.1 48.1 72.7 144.2 47.3 60.9 123.3 85.9 119.0 115.2 74.4 41.0 203.2 213.9 132.6 170.6 47.2 49.5 149.9 173.4 182.2 17.3 63.7 54.6 184.9 130.5 70.1 104.4 44.7 53.4 91.4 108.2 29.2 79.1 29.4 241.6 224.4 130.0 114.3 55.0 34.4 121.3 47.0 50.3 59.7 77.5 26.9 21.8 212.7 142.3 53.6 27.0 108.1 80.1 2.0 273.3 490.3 149.5 435.6 344.8 52.3 203.7 9.6 25.3 18.3 15.5 267.9 48.0 60.2 3.7 477.7 82.4 36.2 22.0 3.0 85.8 137.0 798.5 0.5 127.7 586.5 775.8 476.2 147.1 309.3 275.3 1.4 5.1 120.8 604.2 57.4 3.9 11.3 10.2 112.8 15.5 54.4 67.1 31.9 91.2 201.5 36.7 35.6 101.3 8.4 21.3 185.2 32.7 111.2 155.8 91.5 86.9 6.2 36.4 202.0 42.9 54.5 118.7 9.9 261.0 0.0 22.8 0.5 0.5 52.2 0.8 20.7 1.1 0.6 20.0 16.2 0.3 0.4 4.2 0.7 74.5 21.5 2.9 34.2 47.0 48.1 47.3 60.9 47.2 49.5 63.7 54.6 53.4 55.0 50.3 53.6 571.2 83.3 45.1 1.0 126.9 440.5 340.1 293.1 512.8 0.8 203.9 187.6 151.6 41.5 214.4 68.0 0.0 42.1 56.4 505.3 46.9 217.6 0.9 227.9 57.3 327.1 175.5 5.7 0.5 264.7 52.8 302.4 150.9 199.2 104.4 20.4 71.7 68.9 72.9 0.0 0.4 197.1 156.6 62.0 556.0 3.9 34.5 277.6 218.7 5.6 280.6 58.4 2.1 0.0 0.5 429.9 466.1 16.6 376.4 201.7 383.2 17.2 215.1 3.1 26.3 303.6 471.6 1.2 1.7 620.9 672.0 155.3 106.0 10.7 75.8 478.0 CDKN1C "BWCR, BWS, KIP2, P57" ENSG00000129757 "Cyclin dependent kinase inhibitor 1C" P49918 11 2883213-2885775 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 206.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 575.3;Extravillous trophoblasts: 1531.7;Syncytiotrophoblasts: 2241.2;Theca cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 155.1;non-classical monocyte: 376.4" "Lineage enriched" "Detected in many" 14 "monocytes: 376.4" "Cell line enhanced" "Detected in many" "EFO-21: 12.0;HeLa: 12.8;RPMI-8226: 18.7;SH-SY5Y: 33.0;SiHa: 25.2;SK-MEL-30: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002924 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Nuclear bodies" Cytosol "HPA002924: AB_1079548" "unprognostic (5.49e-3)" "unprognostic (2.62e-1)" "unprognostic (9.82e-3)" "unprognostic (5.79e-3)" "unprognostic (4.15e-1)" "unprognostic (2.84e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-1)" "unprognostic (3.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.95e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-1)" "unprognostic (3.31e-2)" "unprognostic (8.53e-2)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" 127.4 182.9 8.2 3.3 38.0 1.7 92.5 43.3 18.7 73.7 6.5 48.1 1.4 70.6 0.2 29.9 70.7 0.8 82.6 11.7 18.8 149.5 8.3 34.5 0.2 55.1 33.5 206.4 28.5 0.2 27.8 28.1 45.0 33.1 0.2 0.5 21.7 1.5 60.3 26.6 25.0 0.4 31.8 20.6 54.1 8.6 34.3 0.2 17.0 0.9 0.4 75.0 49.4 95.3 0.1 0.1 1.6 0.0 0.4 0.5 1.8 0.3 0.6 0.3 0.0 3.3 0.4 0.0 12.0 0.2 0.1 0.5 0.3 0.3 0.1 5.6 1.2 0.1 12.8 0.0 3.3 0.0 1.4 2.4 1.6 0.0 0.2 0.1 0.3 0.1 2.7 0.8 0.5 0.1 0.0 6.0 10.6 0.5 4.0 2.2 0.0 18.7 0.7 0.0 3.5 33.0 25.2 0.3 15.2 0.9 0.2 2.8 0.4 0.0 2.2 0.0 0.1 7.3 0.0 0.1 0.0 1.8 6.8 9.1 1.2 0.9 0.4 155.1 1.8 0.0 0.4 0.6 26.9 0.3 1.0 0.3 2.2 0.0 376.4 0.2 0.7 14.7 8.2 38.0 43.3 18.7 11.7 18.8 55.1 33.5 45.0 31.8 34.3 95.3 357.3 3.2 5.8 1.0 11.6 10.7 81.7 4.9 30.7 11.9 81.0 150.5 45.3 61.5 10.8 31.3 6.2 575.3 46.9 20.3 15.6 9.8 176.5 38.8 101.5 100.8 106.5 0.8 0.6 0.6 1531.7 141.0 17.9 56.2 0.0 31.2 74.6 4.0 91.0 8.4 1.2 25.0 12.2 23.5 23.2 276.4 74.3 54.9 35.6 4.7 14.1 68.3 0.0 3.5 65.7 4.3 4.2 44.4 12.9 64.6 4.0 78.5 7.5 27.4 32.9 238.3 71.4 2.1 3.5 17.3 11.8 2241.2 25.1 781.8 15.2 71.8 CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.2;intestine: 30.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 240.7;Pancreatic endocrine cells: 164.5;Proximal enterocytes: 139.0;Squamous epithelial cells: 142.0;Urothelial cells: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.1;HaCaT: 35.0;HeLa: 33.9;hTERT-RPE1: 60.1;SiHa: 48.0;SK-MEL-30: 35.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB000349: , HPA052838: , HPA063327: AB_2684987" "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" 18.7 1.9 2.0 2.9 1.8 0.4 8.6 1.1 1.9 9.6 9.1 22.4 21.7 3.8 0.6 36.2 1.7 2.4 1.0 1.6 2.2 1.2 1.2 12.6 1.1 2.7 1.5 0.9 1.2 3.3 3.5 2.3 2.3 3.6 19.7 2.8 6.7 4.7 7.2 12.9 30.9 2.1 1.7 4.6 6.0 5.3 2.4 0.8 1.1 1.1 8.1 7.9 20.2 2.4 0.0 0.0 0.3 2.1 28.2 38.1 0.7 1.8 0.0 4.6 12.6 3.6 10.3 0.0 3.4 2.3 0.0 35.0 0.8 6.9 5.5 2.6 9.7 0.0 33.9 1.5 14.4 1.1 6.1 8.1 0.0 6.5 25.8 60.1 4.4 0.0 0.0 17.1 7.3 2.8 0.0 0.1 1.7 1.7 19.5 0.0 2.4 0.7 10.0 0.0 5.4 0.1 48.0 11.5 35.7 25.8 3.0 0.0 14.8 0.0 0.7 0.1 0.0 13.5 8.4 0.1 0.0 1.0 0.0 0.0 3.3 0.0 0.1 3.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.0 9.0 0.0 0.0 1.0 2.0 1.8 1.1 1.9 1.6 2.2 2.7 1.5 2.3 1.7 2.4 2.4 3.5 67.3 6.7 0.3 2.9 5.4 27.0 40.5 5.7 3.2 6.4 9.8 3.1 1.5 37.5 5.5 0.0 1.2 3.2 240.7 0.0 57.7 11.3 31.8 7.5 4.1 7.7 0.0 0.1 38.2 0.8 11.5 30.5 37.2 0.0 0.4 1.8 0.1 1.2 0.0 0.5 31.6 14.2 17.6 3.8 2.7 0.6 5.6 3.6 2.8 3.2 4.8 0.0 1.0 0.5 164.5 75.6 1.2 2.1 65.3 139.0 0.1 17.9 7.2 0.0 2.7 8.9 13.8 3.5 142.0 24.2 3.1 2.9 1.2 23.3 241.6 CDKN2C "INK4C, p18" ENSG00000123080 "Cyclin dependent kinase inhibitor 2C" P42773 1 50960745-50974634 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 98.4;lymphoid tissue: 96.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 73.5;Sertoli cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 273.1;U-937: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005303, CAB018398, HPA019057, HPA019764" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB005303: AB_2078729, CAB018398: AB_2078731, HPA019057: AB_1854865, HPA019764: AB_1854866" "unprognostic (4.07e-2)" "unprognostic (1.47e-3)" "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "unprognostic (6.70e-2)" "unprognostic (4.76e-3)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.70e-10)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.24e-1)" 98.4 23.2 21.6 9.1 23.6 36.0 30.6 22.6 31.4 17.5 20.3 19.3 13.4 20.4 11.8 11.1 15.2 15.5 24.2 21.6 23.0 10.4 7.2 9.9 22.5 23.0 22.4 47.6 17.4 19.9 7.8 7.3 24.0 9.9 12.6 7.8 8.8 24.9 20.5 18.9 14.2 22.2 21.2 11.1 7.4 5.2 22.2 96.2 9.7 8.6 23.4 13.1 16.3 30.3 67.6 32.9 5.9 99.6 108.0 16.4 1.5 61.8 76.2 121.8 107.8 1.8 25.7 140.3 58.5 63.5 41.6 8.2 71.4 9.8 63.4 78.4 90.7 102.5 254.6 21.5 5.5 74.0 42.8 5.6 1.9 32.8 14.6 45.6 32.7 115.0 45.0 0.0 76.2 22.0 91.1 40.4 0.1 31.6 71.3 108.6 86.8 0.4 42.9 34.1 49.6 114.3 88.1 67.5 23.6 0.6 31.3 273.1 21.6 130.8 44.1 76.3 0.9 128.1 131.9 113.2 0.0 284.5 118.3 22.4 3.7 17.9 7.3 2.2 8.4 4.9 10.8 9.7 9.3 4.3 6.0 5.8 0.4 10.5 0.9 11.5 22.0 5.6 21.6 23.6 22.6 31.4 21.6 23.0 23.0 22.4 24.0 21.2 22.2 30.3 9.5 0.0 3.9 2.0 5.6 10.1 2.6 8.1 23.9 8.2 3.8 29.5 14.3 5.7 6.1 3.7 16.7 4.9 11.3 2.8 17.6 6.3 4.9 1.1 18.2 8.1 8.4 73.5 0.6 3.4 12.1 31.0 3.1 1.2 16.5 12.6 20.3 8.8 28.3 5.0 0.6 10.2 14.2 20.5 16.0 7.1 39.4 11.0 7.2 1.9 17.1 26.9 17.5 2.0 3.3 3.1 10.2 47.8 14.0 1.8 24.6 40.8 3.2 9.9 85.5 38.9 26.7 32.0 15.0 22.0 11.2 1.9 18.2 28.6 9.1 1.2 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 119.3 18.1 26.1 3.3 28.2 0.2 35.9 24.6 31.2 9.5 109.8 4.8 0.7 8.3 140.3 3.5 13.7 10.5 26.1 28.3 30.7 3.1 506.7 11.7 6.6 23.6 26.2 25.8 14.2 0.7 20.7 35.2 25.6 9.1 1.8 15.9 7.2 72.8 8.5 3.0 4.0 6.2 25.6 3.7 4.1 15.6 26.7 1.3 9.6 19.9 3.1 8.1 5.7 25.6 0.0 0.0 48.1 0.0 57.9 22.3 0.2 1.4 0.4 4.6 4.5 0.0 0.0 0.0 0.0 0.6 17.2 0.1 17.1 0.0 6.6 0.1 8.5 1.7 0.0 1.4 0.2 0.1 0.0 8.5 0.0 0.7 0.0 1.2 6.3 0.0 0.0 0.0 5.5 0.0 1.2 0.2 17.8 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 11.0 0.1 0.0 0.0 4.0 0.0 5.4 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 26.1 28.2 24.6 31.2 28.3 30.7 23.6 26.2 25.6 25.6 26.7 25.6 4.1 0.0 1.3 6.8 0.7 0.8 0.8 0.0 0.6 27.3 1.0 7.1 3.4 0.0 0.0 1.8 6.2 329.4 0.3 0.0 0.0 9.9 6.0 0.3 7.1 3.1 1.8 2.7 12.2 0.2 17.0 27.8 0.0 0.3 0.0 7.5 33.9 149.5 23.4 1.7 16.4 0.0 0.0 5.7 1.6 15.0 91.0 0.6 1.8 1.0 0.6 31.4 0.0 5.5 3.1 0.3 0.0 37.6 0.0 0.9 0.0 2.0 0.0 3.8 13.1 7.3 3.9 1.6 1.4 0.5 1.3 481.9 0.9 104.7 0.0 0.1 CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.3;Fibroblasts: 23.5;Inhibitory neurons: 49.5;Muller glia cells: 39.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;ASC diff: 32.7;RH-30: 48.9;SuSa: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" 12.6 0.7 1.9 1.6 2.0 0.0 5.1 23.0 4.0 7.9 1.2 12.4 1.0 14.0 2.1 1.7 14.2 4.8 4.0 1.6 1.8 0.8 1.2 2.7 1.1 2.2 1.9 20.6 1.2 2.5 3.0 2.7 2.7 1.3 1.6 10.1 1.7 2.8 1.2 9.9 2.9 17.0 0.5 0.7 4.6 3.6 2.3 2.8 18.5 1.6 1.5 2.5 3.0 2.1 1.6 3.2 28.4 2.8 32.7 14.5 0.4 0.5 2.9 0.9 0.3 1.1 9.4 1.4 6.8 0.6 3.3 0.4 7.1 1.0 0.8 5.5 6.3 0.5 6.5 2.9 6.4 0.4 1.8 4.5 1.2 0.6 0.0 12.2 0.3 4.8 0.1 1.9 2.7 0.4 3.6 1.0 2.6 0.8 3.7 1.1 48.9 0.9 1.7 0.5 2.4 9.6 3.7 0.3 4.7 23.8 2.4 1.0 0.5 3.2 2.2 6.3 3.3 2.5 5.5 0.2 2.0 1.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 23.0 4.0 1.6 1.8 2.2 1.9 2.7 0.5 2.3 2.1 3.0 6.4 9.9 11.1 0.1 15.2 1.4 0.8 2.2 5.1 5.4 1.9 5.2 2.8 5.6 0.0 16.7 0.6 0.1 0.2 0.0 1.3 3.1 1.7 0.5 3.0 7.7 0.4 58.3 0.6 0.4 23.5 1.5 1.1 0.0 1.8 1.1 2.1 0.3 0.0 49.5 0.3 0.0 0.0 7.6 2.7 14.9 0.2 3.6 2.8 0.1 39.3 0.0 14.1 5.8 2.4 0.4 11.3 0.8 1.1 0.6 0.5 4.2 4.6 0.0 2.9 2.7 1.8 3.8 0.5 10.7 0.7 0.6 13.2 0.4 1.6 CDR2 "CDR62, Yo" ENSG00000140743 "Cerebellar degeneration related protein 2" Q01850 16 22345936-22437165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 70.2;Spermatocytes: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 8.4;NK-cells: 2.5;T-cells: 6.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018151, HPA023870" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA018151: AB_1846457, HPA023870: AB_1846459" "unprognostic (7.89e-2)" "unprognostic (1.55e-1)" "unprognostic (5.23e-2)" "unprognostic (3.09e-1)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (2.75e-1)" "unprognostic (2.55e-1)" "unprognostic (1.06e-1)" "unprognostic (9.86e-2)" "unprognostic (3.04e-1)" "unprognostic (2.04e-2)" "unprognostic (3.34e-3)" "unprognostic (1.38e-2)" "unprognostic (5.78e-2)" "unprognostic (1.67e-3)" 19.1 12.0 9.5 19.0 17.7 23.9 14.6 13.6 10.9 18.8 32.0 22.5 28.6 17.8 10.3 12.1 15.9 22.2 14.3 9.8 9.5 25.0 22.9 21.6 25.4 8.6 7.6 14.9 13.9 13.2 21.8 15.0 8.5 20.7 19.3 74.0 15.7 23.1 5.9 10.6 22.1 27.2 5.0 18.7 17.5 62.0 10.5 28.2 49.0 5.6 19.3 29.2 14.0 8.3 38.9 26.8 22.8 24.2 55.2 47.4 23.9 36.4 57.0 36.7 48.4 35.3 25.9 33.3 19.3 62.4 22.2 36.5 49.2 20.8 43.0 26.2 25.1 25.3 29.4 111.0 63.4 27.6 49.6 35.6 18.8 36.2 40.3 46.3 46.2 42.6 25.1 53.3 35.4 28.0 27.8 20.0 32.4 32.3 22.0 40.1 29.4 49.5 45.7 24.8 17.5 12.5 24.8 51.9 36.4 25.7 15.4 13.7 31.9 36.2 22.9 34.5 32.9 27.6 49.7 46.9 23.8 27.1 31.7 8.4 0.8 1.2 1.6 0.7 3.6 0.9 5.3 3.4 0.9 0.6 4.1 3.5 0.7 2.5 0.9 1.1 6.5 1.7 9.5 17.7 13.6 10.9 9.8 9.5 8.6 7.6 8.5 5.0 10.5 8.3 18.2 3.2 5.1 3.6 8.7 34.0 17.3 4.3 15.4 8.9 27.4 9.1 3.5 10.0 7.0 9.2 14.6 1.7 12.7 22.0 1.9 8.7 36.7 6.9 10.0 13.9 6.6 17.2 8.0 7.1 10.8 19.6 19.4 12.0 0.0 9.6 10.0 9.5 9.4 8.4 10.5 16.1 6.1 5.0 11.5 8.8 6.8 7.4 10.6 2.8 4.0 10.1 4.1 3.5 2.2 13.8 12.2 10.9 24.9 19.4 22.4 12.4 4.9 70.2 6.6 9.7 15.8 50.9 16.1 8.7 24.3 1.4 25.8 2.7 7.8 14.8 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cell line enhanced" "Detected in many" "BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 98.7 2.9 16.2 5.7 17.9 22.6 67.7 18.3 26.9 8.7 10.4 21.0 21.2 2.9 0.8 20.9 4.3 3.0 2.8 15.7 18.8 3.6 194.7 25.5 9.1 27.4 22.4 1.3 9.7 26.8 2.6 16.0 21.3 8.8 11.5 0.6 9.8 3.4 19.1 118.7 20.8 2.5 25.7 7.7 12.5 1.0 24.5 4.1 6.5 4.5 6.3 8.7 14.8 34.8 2.5 5.1 0.1 7.1 55.8 0.0 196.9 0.1 1.5 0.1 0.0 24.8 0.1 0.0 3.0 0.0 1.1 9.4 5.8 0.6 0.0 35.8 7.2 0.1 0.1 110.9 0.9 36.6 42.1 2.2 25.4 0.0 0.2 0.0 0.0 2.8 2.4 0.0 0.0 12.7 0.2 114.1 5.0 61.8 2.7 0.0 0.4 1.1 0.2 17.7 0.4 1.7 0.7 0.5 0.8 6.2 13.7 407.7 0.1 0.1 0.8 0.1 0.9 0.4 0.0 0.2 0.0 130.9 0.0 16.0 7.1 0.0 0.8 12.3 0.7 0.0 0.1 0.5 5.1 0.1 0.2 0.4 2.5 0.0 15.7 0.2 0.0 2.1 16.2 17.9 18.3 26.9 15.7 18.8 27.4 22.4 21.3 25.7 24.5 34.8 5.4 16.0 37.8 0.0 2.8 37.3 20.8 3.3 22.2 0.7 6.2 12.2 0.4 57.2 5.1 0.0 0.0 40.3 14.4 91.6 3.9 0.5 0.0 0.8 0.8 4.9 4.2 5.7 1.9 5.8 44.3 9.5 12.8 1.3 1.3 0.0 2.2 106.5 87.0 0.0 0.3 24.8 4.1 35.0 27.4 0.2 3.1 42.9 5.4 17.8 28.2 8.4 6.2 1.0 0.4 1.9 30.6 1.5 2.0 15.1 42.5 4.9 5.1 0.5 0.0 4.1 3.1 0.2 0.7 29.7 171.8 212.3 5.0 0.3 51.5 12.2 CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 1061.4;Late spermatids: 1606.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 32.0;RH-30: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" 11.3 3.9 5.0 2.7 5.4 1.7 9.5 7.1 5.8 8.3 11.9 7.8 2.0 8.5 8.2 4.3 8.3 7.0 8.0 7.4 5.1 5.6 3.2 7.4 2.5 5.8 5.7 8.2 4.6 8.7 8.3 7.2 4.2 7.2 3.1 25.4 3.0 7.9 8.8 3.3 2.9 8.0 3.4 8.8 4.2 49.0 5.5 2.8 7.1 14.0 1.7 5.4 5.9 3.4 5.0 10.5 13.3 3.8 6.9 14.0 0.4 4.5 7.7 5.5 5.0 1.5 2.0 1.6 4.3 9.8 15.5 0.6 2.9 2.9 7.8 2.6 4.8 0.3 4.7 1.9 2.9 0.6 0.2 8.4 4.8 5.2 1.6 11.0 16.8 2.7 0.3 5.0 32.0 0.7 5.3 0.4 1.3 1.1 4.4 1.5 75.9 0.4 6.0 0.3 3.5 7.4 4.7 0.5 3.6 11.4 3.8 0.4 7.9 14.3 8.2 3.9 6.7 2.3 2.1 0.2 4.4 0.2 5.3 1.3 0.4 0.4 0.3 0.2 0.6 0.3 0.8 0.3 0.2 0.8 0.5 0.3 1.3 0.8 0.2 1.4 0.5 0.1 5.0 5.4 7.1 5.8 7.4 5.1 5.8 5.7 4.2 3.4 5.5 3.4 39.7 9.6 35.8 83.6 1.1 2.5 2.9 2.2 2.2 36.7 2.7 5.5 28.3 4.3 15.3 1.8 20.9 0.7 0.8 1.5 1.9 7.4 1061.4 15.3 15.8 25.4 1.8 0.4 117.4 4.7 1.5 12.4 1.5 3.3 2.5 11.2 19.2 0.2 1.8 1.7 103.8 0.3 0.0 0.8 11.3 1606.0 24.8 2.3 14.2 99.3 0.0 14.7 1.0 29.7 6.6 4.4 0.5 19.9 0.4 1.5 0.0 4.3 23.7 154.3 13.1 43.7 12.5 40.6 16.5 2.4 1.6 0.1 2.5 3.1 1.5 1.3 CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 71.3;Muller glia cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 55.1;NB-4: 99.8;U-937: 61.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" 13.6 13.0 31.8 10.0 38.9 3.4 31.1 26.6 37.1 35.9 18.7 17.7 6.3 21.5 61.5 64.3 21.3 11.2 14.8 35.3 25.2 27.8 57.7 19.4 19.9 36.9 30.5 22.0 89.1 29.0 22.2 1.9 30.8 32.9 3.9 36.9 55.0 17.6 3.1 47.7 15.2 12.0 26.8 17.7 26.8 11.5 30.7 13.1 51.9 5.3 20.4 18.4 32.7 44.0 0.4 2.1 2.1 25.0 0.8 0.2 1.7 3.1 8.4 3.7 1.7 19.5 1.7 40.0 27.4 0.0 9.6 13.6 16.4 0.4 1.7 35.5 12.4 7.6 0.1 55.1 31.6 0.0 21.3 12.3 20.7 8.8 18.9 10.5 0.3 17.7 5.9 1.2 0.0 0.8 2.6 99.8 25.4 0.2 8.7 49.1 0.8 3.0 6.3 0.0 9.3 12.2 4.3 0.7 14.5 16.7 18.8 8.8 0.2 2.9 7.8 18.6 0.1 24.5 21.1 32.0 0.1 61.9 2.8 12.3 7.1 27.4 7.5 3.9 5.7 19.8 4.3 4.6 4.1 17.7 3.9 3.8 22.4 22.4 2.4 3.9 5.5 5.8 31.8 38.9 26.6 37.1 35.3 25.2 36.9 30.5 30.8 26.8 30.7 44.0 3.2 6.4 10.7 27.1 31.2 18.0 13.2 12.0 15.4 24.5 47.0 28.8 4.1 22.8 22.2 1.8 18.8 3.4 17.2 0.2 7.9 20.0 1.7 7.9 11.2 8.6 23.9 4.0 38.3 30.5 0.9 15.7 3.1 7.6 12.7 14.4 8.2 71.3 16.4 11.8 24.4 1.3 8.2 7.1 7.2 7.3 14.3 6.7 26.6 16.9 19.6 150.3 27.8 47.7 48.1 9.4 2.5 16.1 12.4 40.6 0.4 44.6 27.8 29.5 6.6 6.9 13.8 1.0 1.6 20.6 25.9 2.9 15.7 2.7 2.5 11.9 CERT1 "CERT, COL4A3BP, GPBP, STARD11" ENSG00000113163 "Ceramide transporter 1" Q9Y5P4 5 75356345-75512138 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.3;Cardiomyocytes: 37.1;Cytotrophoblasts: 17.7;dendritic cells: 20.2;Extravillous trophoblasts: 16.8;Hofbauer cells: 36.8;Plasma cells: 12.4;Syncytiotrophoblasts: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 132.3;WM-115: 118.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035645, HPA042608" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA035645: AB_10600700, HPA042608: AB_2678075" "unprognostic (2.45e-1)" "unprognostic (7.16e-2)" "unprognostic (6.56e-3)" "unprognostic (1.53e-2)" "unprognostic (2.44e-1)" "unprognostic (9.29e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.29e-2)" "prognostic favorable (1.24e-5)" "unprognostic (9.12e-2)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (2.91e-1)" 38.1 26.1 12.4 16.5 16.1 27.2 17.6 18.0 15.4 33.9 14.0 20.8 18.7 20.6 15.1 24.9 22.4 23.3 20.8 14.0 15.1 27.9 31.2 24.3 20.3 14.7 17.5 23.1 16.4 26.1 8.0 22.9 16.7 24.3 19.6 18.2 14.0 19.9 28.9 18.7 21.1 18.3 14.7 25.3 23.5 28.8 15.5 21.2 49.9 28.3 22.7 23.7 16.0 17.6 44.9 22.7 21.6 19.0 132.3 36.6 29.0 24.8 30.8 18.8 24.8 34.4 25.3 21.5 52.3 26.9 25.8 26.7 33.4 34.4 28.6 27.1 15.2 18.2 24.4 18.4 33.6 18.2 20.1 27.9 23.8 22.3 24.9 30.5 22.1 28.3 33.0 32.0 25.0 23.0 21.6 13.2 27.9 10.2 16.8 18.0 28.5 20.2 30.5 54.0 16.4 16.5 31.6 21.6 31.8 45.4 21.3 30.5 30.1 12.6 15.1 22.8 20.3 29.1 41.6 24.8 21.4 30.7 118.2 9.6 19.8 16.0 8.2 22.4 7.8 9.1 8.3 7.7 14.5 9.1 7.7 7.8 29.6 7.8 25.4 8.3 13.0 9.0 12.4 16.1 18.0 15.4 14.0 15.1 14.7 17.5 16.7 14.7 15.5 17.6 23.3 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 17.7 20.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 16.8 10.5 0.0 0.0 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 27.8 3.8 0.0 0.0 0.0 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2517.1" "Group enriched" "Detected in many" 7 "Cholangiocytes: 613.4;Hepatocytes: 2420.8" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.6;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.6" "Group enriched" "Detected in some" 5 "Hep G2: 700.9;THP-1: 688.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 94.9 14.1 0.9 3.2 1.2 27.0 43.6 0.8 1.8 26.6 3.7 82.3 24.0 60.4 7.5 41.1 54.6 272.9 66.1 1.0 1.4 6.7 2517.1 167.8 1.8 2.3 1.2 20.3 8.8 0.7 3.7 8.5 1.5 39.2 12.3 2.9 41.4 36.4 5.2 14.0 27.4 40.4 1.0 41.0 56.1 7.8 1.1 2.5 9.9 9.4 1.0 57.7 17.7 1.1 0.7 4.4 0.0 0.0 90.8 0.6 3.1 0.3 0.0 0.0 0.0 43.5 0.0 0.0 19.4 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.9 700.9 0.0 1.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 40.8 0.1 0.6 0.0 0.0 1.5 6.7 0.0 0.5 0.0 0.1 3.2 0.1 1.1 0.9 0.0 688.0 0.1 0.0 0.4 0.2 0.5 2.2 0.1 1.0 0.0 151.7 0.0 0.0 109.6 0.5 4.5 6.1 1.5 1.1 0.7 5.0 114.5 1.2 0.7 1.1 0.6 0.3 1.6 6.8 0.4 58.0 0.9 1.2 0.8 1.8 1.0 1.4 2.3 1.2 1.5 1.0 1.1 1.1 2.0 16.0 67.6 0.0 11.3 16.7 5.3 6.8 1.2 0.0 1.2 8.1 0.8 613.4 31.5 16.5 0.0 0.5 12.2 0.1 0.0 15.4 79.6 1.0 10.6 8.9 37.5 177.7 0.0 18.7 2.2 57.4 1.1 0.2 6.3 0.0 66.0 2420.8 18.1 0.0 0.0 12.2 4.1 107.3 26.7 197.8 18.6 58.7 39.2 1.0 39.6 10.4 7.2 0.0 0.0 0.9 1.3 98.9 1.8 1.5 0.6 0.9 169.0 0.9 0.0 9.8 9.8 1.0 2.3 20.6 11.6 0.8 16.9 0.9 0.7 2.6 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.2;liver: 52.5;skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 120.1;Granulosa cells: 58.5;Hepatocytes: 53.4;Intestinal goblet cells: 32.0;Paneth cells: 67.0;Proximal enterocytes: 66.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 7.4;Daudi: 8.5;JURKAT: 13.5;U-937: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" NA NA 1200000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.8 0.5 3.1 3.2 2.7 0.9 2.3 2.5 2.9 1.3 1.3 38.2 30.0 0.7 0.2 4.2 2.9 0.9 0.7 3.8 2.0 12.2 52.5 0.7 0.3 3.3 2.7 0.6 4.1 1.0 1.9 0.6 3.5 0.5 31.3 0.6 12.0 0.3 24.7 1.2 23.7 1.2 1.4 0.4 7.7 1.1 2.2 0.2 0.4 1.5 0.2 0.1 0.8 2.2 0.4 3.1 0.3 7.4 0.2 0.2 1.2 0.2 0.2 0.3 0.5 0.5 3.8 8.5 2.4 0.0 0.2 0.6 1.1 0.5 0.1 1.5 5.5 4.3 1.3 2.6 0.0 0.9 0.7 0.3 0.9 0.8 0.1 0.2 0.0 13.5 2.8 1.7 0.3 1.1 1.4 1.4 1.5 2.6 0.4 1.3 0.7 1.3 0.1 0.4 0.4 0.8 0.2 5.8 0.2 0.6 5.0 6.5 0.3 0.4 2.4 0.7 0.2 0.9 3.6 1.3 0.3 7.2 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 3.1 2.7 2.5 2.9 3.8 2.0 3.3 2.7 3.5 1.4 2.2 2.2 0.1 3.2 6.7 0.7 0.4 0.5 0.0 1.3 1.2 0.2 9.1 5.7 1.4 2.8 0.9 0.0 0.0 0.0 0.0 120.1 0.0 0.2 0.5 3.2 0.3 0.2 19.7 0.0 1.8 0.9 0.0 0.2 11.7 4.4 1.3 58.5 0.4 53.4 0.3 0.0 2.9 32.0 0.0 3.2 0.9 5.4 0.0 0.9 0.0 0.0 0.0 0.4 0.0 1.5 0.1 1.0 67.0 1.2 0.1 0.1 66.0 9.9 4.8 0.2 0.0 0.6 0.2 2.3 2.9 1.1 0.3 0.0 0.4 0.1 44.3 0.2 CFAP46 "bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, C10orf123, C10orf124, C10orf92, C10orf93, DKFZp434A1721, FLJ25954, TTC40" ENSG00000171811 "Cilia and flagella associated protein 46" Q8IYW2 10 132808392-132942823 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 22.5;skeletal muscle: 33.4;testis: 41.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.9;Endometrial ciliated cells: 70.8;Excitatory neurons: 42.8;Respiratory ciliated cells: 59.0;Rod photoreceptor cells: 74.4;Spermatocytes: 53.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SH-SY5Y: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037786, HPA038034, HPA038867, HPA038868" Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA037786: AB_10672392, HPA038034: AB_2675796, HPA038867: AB_2676246, HPA038868: AB_2676247" "unprognostic (2.83e-2)" "unprognostic (4.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.19e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-1)" "unprognostic (4.11e-1)" "unprognostic (5.40e-2)" "unprognostic (6.41e-3)" "unprognostic (1.39e-1)" "unprognostic (1.64e-4)" "unprognostic (1.21e-2)" "unprognostic (8.08e-2)" "unprognostic (4.56e-3)" "unprognostic (2.08e-2)" 0.0 0.2 5.9 0.0 7.0 0.0 0.1 4.2 10.0 1.5 22.5 0.0 0.1 0.1 1.3 0.2 16.1 0.1 0.7 6.5 6.1 1.0 0.2 3.4 0.0 13.5 17.3 0.2 0.4 1.1 2.2 0.0 8.5 0.2 0.0 3.9 0.4 0.4 33.4 0.1 0.1 0.0 9.4 0.1 2.4 41.8 6.6 0.0 4.2 10.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.2 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 5.9 7.0 4.2 10.0 6.5 6.1 13.5 17.3 8.5 9.4 6.6 4.6 0.2 0.0 4.8 9.8 0.3 0.0 0.5 0.0 0.6 6.3 1.3 1.1 3.7 0.0 9.3 7.3 95.9 0.0 0.0 0.0 5.9 4.8 18.0 70.8 0.9 0.9 0.0 0.0 42.8 0.2 0.0 1.5 5.1 1.5 3.8 4.3 5.0 0.2 0.6 1.7 22.0 0.0 0.0 0.6 0.0 11.3 1.2 0.3 0.0 1.0 0.0 4.7 0.0 2.0 0.9 1.6 0.0 2.2 0.2 0.7 0.0 5.6 59.0 74.4 0.0 0.4 0.4 53.7 7.2 0.7 0.0 0.0 0.3 7.3 0.0 0.6 CFAP73 "CCDC42B, MIA2" ENSG00000186710 "Cilia and flagella associated protein 73" A6NFT4 12 113149858-113159276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 21.6;choroid plexus: 28.1;fallopian tube: 42.2" "Cell type enriched" "Detected in some" 4 "Endometrial ciliated cells: 110.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 4.3;REH: 2.2;T-47d: 2.5;U-698: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048539 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA048539: AB_2680434" "unprognostic (2.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.90e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.18e-3)" "unprognostic (6.49e-2)" "unprognostic (2.94e-1)" "unprognostic (1.33e-1)" "unprognostic (3.14e-1)" "unprognostic (5.68e-2)" "unprognostic (3.43e-2)" "unprognostic (1.62e-4)" "unprognostic (2.03e-4)" "unprognostic (1.60e-1)" "unprognostic (4.03e-2)" "unprognostic (1.55e-2)" 0.2 0.4 3.2 0.4 2.8 2.1 0.3 1.1 1.0 3.8 28.1 0.3 0.3 0.5 0.3 0.5 42.2 0.2 0.2 5.5 5.8 1.7 0.5 7.1 0.7 17.9 21.6 0.4 0.4 0.1 1.2 0.0 11.3 0.6 0.0 0.2 2.3 0.7 0.3 4.7 0.5 0.0 15.0 0.6 4.0 0.5 4.6 0.0 0.8 0.0 1.2 0.2 0.2 3.4 0.2 0.0 0.2 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 2.0 4.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.2 1.7 0.1 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.7 0.2 0.7 0.3 0.8 0.1 2.2 0.0 0.3 0.5 0.5 0.4 0.1 0.0 0.6 0.0 0.2 2.5 0.0 0.1 0.1 0.7 0.2 0.1 0.4 0.1 9.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.8 1.1 1.0 5.5 5.8 17.9 21.6 11.3 15.0 4.6 3.4 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 6.2 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.4 110.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.6 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.3 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.1 23.3 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.1 0.2 CFAP99 ENSG00000206113 "Cilia and flagella associated protein 99" 4 2418974-2462942 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;choroid plexus: 5.8;fallopian tube: 3.9;retina: 1.5;testis: 5.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Early spermatids: 11.6;Endometrial ciliated cells: 13.6;Late spermatids: 11.2;Rod photoreceptor cells: 5.5;Spermatocytes: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA071642 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA071642: " "unprognostic (7.54e-3)" "unprognostic (6.46e-3)" "unprognostic (1.12e-1)" "unprognostic (2.31e-3)" "unprognostic (2.68e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.89e-1)" "unprognostic (8.14e-2)" "unprognostic (7.93e-5)" "unprognostic (1.15e-1)" "unprognostic (5.97e-3)" "unprognostic (1.92e-2)" "unprognostic (1.36e-1)" "unprognostic (6.94e-2)" "unprognostic (3.49e-1)" 0.0 0.8 0.5 0.0 0.5 0.0 0.0 0.8 0.3 0.2 5.8 0.0 0.0 0.2 0.1 0.0 3.9 0.0 0.0 0.9 0.8 0.2 0.1 0.6 0.0 3.2 4.8 0.0 0.3 0.0 0.8 0.0 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 5.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 0.3 0.9 0.8 3.2 4.8 1.8 2.0 1.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.2 0.0 1.8 3.7 4.2 0.0 0.0 0.0 0.0 0.2 11.6 13.6 0.2 0.1 0.0 0.0 1.2 0.6 0.1 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 1.5 2.9 5.5 0.0 0.0 0.0 14.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 CHAC2 GCG1 ENSG00000143942 "ChaC glutathione specific gamma-glutamylcyclotransferase 2" Q8WUX2 2 53767804-53775196 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 44.0;Plasma cells: 27.0;Spermatocytes: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049235 Approved Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA049235: AB_2680686" "unprognostic (2.22e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (3.91e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "prognostic unfavorable (3.80e-7)" "unprognostic (5.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.30e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (4.28e-6)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" 5.0 4.4 1.6 4.8 1.7 6.9 2.1 2.4 2.4 1.2 0.9 4.4 7.3 1.1 2.6 4.5 0.7 1.3 2.5 1.6 2.0 2.9 4.4 1.4 6.6 1.6 1.6 0.6 1.9 1.3 1.6 1.1 1.5 1.7 3.7 3.7 1.7 1.5 4.9 1.2 4.5 2.2 1.3 4.2 4.5 5.4 1.8 4.9 1.0 4.7 6.5 3.2 2.2 1.4 39.9 13.0 13.5 12.1 6.7 3.3 2.9 17.9 3.6 12.5 14.8 9.1 10.0 33.5 25.3 7.8 18.8 14.0 31.1 21.3 21.7 71.3 27.1 26.6 16.3 15.0 10.2 31.8 11.6 4.2 6.2 23.2 17.5 3.3 24.8 23.0 27.8 19.2 16.6 13.0 38.0 26.5 17.5 17.1 23.1 28.6 28.9 34.2 17.3 10.6 16.8 4.7 20.7 15.3 8.7 8.1 9.3 12.5 11.0 7.3 26.1 28.2 29.3 18.9 26.1 28.8 9.9 39.5 10.2 1.3 0.3 0.8 3.5 0.7 3.7 4.3 3.8 3.9 0.8 4.4 4.3 4.1 1.0 1.1 0.5 1.8 3.9 1.9 1.6 1.7 2.4 2.4 1.6 2.0 1.6 1.6 1.5 1.3 1.8 1.4 2.3 0.0 1.1 2.0 11.7 3.4 3.7 7.4 0.6 1.6 2.2 2.0 3.0 7.2 4.1 1.8 0.0 1.9 5.1 3.4 11.7 5.4 13.1 2.2 1.0 3.0 0.0 44.0 4.8 8.0 0.9 1.6 10.2 2.2 1.3 1.5 3.3 7.6 7.8 1.7 4.3 4.6 2.0 1.9 3.0 3.5 2.8 1.7 3.6 1.0 5.8 5.7 8.2 5.0 2.1 7.9 1.4 4.1 27.0 4.1 3.7 9.8 1.9 6.8 0.0 2.4 3.1 47.0 6.6 5.5 3.4 0.4 5.3 5.1 10.6 4.0 CHAD SLRR4A ENSG00000136457 Chondroadherin O15335 17 50464496-50468906 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2;pancreas: 32.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.6;Breast myoepithelial cells: 2.4;Distal enterocytes: 3.3;Gastric mucus-secreting cells: 4.6;Hepatocytes: 2.4;Intestinal goblet cells: 4.3;Oligodendrocyte precursor cells: 5.5;Paneth cells: 2.5;Proximal enterocytes: 2.6" "Group enriched" "Detected in many" 5 "breast cancer: 23.7;liver cancer: 10.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "memory B-cell: 21.5;naive B-cell: 8.0" "Lineage enriched" "Detected in single" 76 "B-cells: 21.5" "Cell line enhanced" "Detected in some" "RT4: 4.0;SCLC-21H: 8.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018241 Enhanced "Secreted to extracellular matrix" NA NA 22000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA018241: AB_1846612" "prognostic favorable (7.68e-4)" "unprognostic (4.34e-2)" "unprognostic (1.24e-1)" "unprognostic (9.67e-3)" "unprognostic (1.92e-1)" "unprognostic (3.06e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.51e-2)" "unprognostic (4.75e-2)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-2)" "unprognostic (1.51e-3)" "unprognostic (1.41e-3)" 2.1 14.1 6.2 0.7 7.9 0.3 9.6 17.4 7.3 21.8 3.9 6.7 7.6 0.5 0.1 1.8 0.8 1.5 1.7 5.5 6.3 2.4 36.2 1.6 0.6 5.6 4.9 3.1 32.6 0.0 1.3 0.5 5.7 1.9 4.0 0.5 21.3 0.2 14.5 8.5 10.3 0.1 5.1 1.1 10.8 1.2 5.8 0.2 4.2 0.9 0.2 1.2 1.6 5.4 1.0 0.8 0.7 0.6 0.0 0.0 2.1 0.1 0.0 0.0 0.0 1.5 0.8 0.1 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.6 0.7 1.2 0.7 1.5 0.0 0.4 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.1 0.7 0.9 0.1 1.5 0.0 4.0 8.5 0.2 0.1 0.3 0.0 0.3 0.3 0.2 0.9 2.1 0.4 0.1 0.0 1.4 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 6.2 7.9 17.4 7.3 5.5 6.3 5.6 4.9 5.7 5.1 5.8 5.4 0.0 0.0 0.0 1.3 1.0 0.3 0.2 0.3 0.0 0.0 4.6 2.4 0.2 1.5 0.2 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.2 4.3 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.5 0.1 0.0 2.5 0.0 1.1 0.2 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.4 CHCHD10 "C22orf16, MIX17A, N27C7-4" ENSG00000250479 "Coiled-coil-helix-coiled-coil-helix domain containing 10" Q8WYQ3 22 23765834-23767972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1622.6;skeletal muscle: 1220.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1264.7;Distal tubular cells: 2498.5;Hepatocytes: 1879.9;Proximal enterocytes: 1501.3;Proximal tubular cells: 1437.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003440 Enhanced Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003440: AB_1078348" "unprognostic (3.88e-2)" "unprognostic (2.36e-3)" "unprognostic (8.90e-2)" "unprognostic (9.80e-2)" "unprognostic (7.68e-2)" "unprognostic (5.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "unprognostic (2.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" "prognostic favorable (2.15e-7)" "unprognostic (5.19e-3)" "unprognostic (2.06e-1)" "unprognostic (5.68e-3)" "unprognostic (2.62e-3)" 216.5 136.5 181.6 30.3 188.3 12.5 144.5 183.0 248.9 77.3 262.6 261.2 92.6 35.5 32.4 147.3 43.1 10.9 1622.6 176.6 190.5 409.5 789.7 56.9 28.6 182.2 182.2 29.0 118.0 220.0 112.3 11.9 187.6 106.4 76.2 63.1 148.3 50.5 1220.9 71.8 159.0 17.9 169.5 100.3 160.2 27.8 204.8 14.0 224.7 660.7 34.5 110.2 89.1 179.3 33.1 66.4 19.7 85.9 42.1 27.7 41.9 11.9 22.8 23.5 28.4 124.1 35.1 113.5 30.7 41.2 12.9 99.8 109.2 34.1 20.5 35.9 140.6 22.5 48.8 117.1 73.8 63.6 108.2 53.3 91.9 35.6 9.3 4.9 29.0 17.2 47.7 48.0 20.6 121.8 21.8 48.2 16.9 194.9 183.5 90.0 4.0 209.0 112.7 55.3 41.3 23.8 13.9 145.7 149.7 36.6 54.9 47.0 15.3 1.0 1.1 18.3 0.2 28.8 11.1 62.5 20.5 54.9 11.2 0.2 4.1 11.2 3.0 9.1 1.9 11.7 3.2 4.0 1.8 10.6 4.9 3.5 0.0 0.8 8.2 7.3 4.3 1.2 181.6 188.3 183.0 248.9 176.6 190.5 182.2 182.2 187.6 169.5 204.8 179.3 88.7 12.8 10.5 36.2 294.8 48.2 415.4 28.2 144.5 136.2 156.9 238.2 503.8 268.8 20.5 419.3 114.7 42.5 104.7 1264.7 2498.5 88.1 27.0 76.6 229.8 47.4 310.5 74.3 38.5 54.5 255.7 67.8 300.7 94.3 84.0 171.9 78.1 1879.9 647.5 99.3 37.6 860.9 26.4 262.1 127.5 18.0 48.7 243.1 373.5 15.9 107.8 188.5 25.7 17.1 17.4 45.9 890.1 29.3 297.3 192.4 1501.3 1437.4 10.0 287.8 124.9 254.0 200.4 32.3 43.4 459.3 43.9 105.2 123.0 216.0 952.4 470.1 CHMP4B "C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B" ENSG00000101421 "Charged multivesicular body protein 4B" Q9H444 20 33811348-33854366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041401, HPA051751" Enhanced NA NA 53000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041401: AB_10965028, HPA051751: AB_2681591" "unprognostic (2.56e-2)" "unprognostic (6.12e-2)" "unprognostic (1.07e-1)" "unprognostic (9.04e-3)" "unprognostic (9.85e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.49e-1)" "unprognostic (4.37e-2)" "unprognostic (1.24e-2)" "unprognostic (6.44e-3)" "unprognostic (1.31e-1)" "unprognostic (6.09e-2)" "unprognostic (2.31e-1)" "unprognostic (5.50e-2)" "unprognostic (1.20e-2)" "unprognostic (3.33e-2)" 105.8 112.3 93.3 75.8 95.3 213.7 102.2 93.9 112.3 112.9 82.5 155.1 103.0 107.8 58.6 159.0 84.4 80.6 147.1 98.4 98.9 122.9 67.7 101.5 70.7 97.7 94.5 94.9 82.1 74.8 74.6 74.7 95.6 90.4 98.7 53.3 118.1 82.4 231.3 120.9 119.9 76.3 93.7 83.0 117.3 60.2 97.5 82.8 88.4 132.6 71.2 132.0 106.9 99.4 206.4 131.3 72.3 69.3 118.8 95.2 114.5 120.4 159.1 126.1 117.5 279.1 171.2 98.1 183.3 122.3 192.0 160.8 83.2 182.3 99.2 51.0 89.3 174.1 90.4 189.3 137.5 86.1 88.1 137.2 99.4 116.3 106.6 125.2 141.9 113.1 84.2 139.0 97.8 130.2 189.8 246.5 63.4 226.3 179.8 97.7 147.2 120.7 142.7 234.0 56.4 68.6 225.0 192.2 165.8 85.1 149.0 123.9 129.9 216.8 85.0 108.7 117.9 132.4 101.3 117.0 176.5 91.6 65.8 0.0 1.8 0.8 0.7 1.7 0.9 1.6 1.1 0.8 1.0 1.1 0.8 0.7 2.3 0.5 1.4 4.0 1.4 0.5 93.3 95.3 93.9 112.3 98.4 98.9 97.7 94.5 95.6 93.7 97.5 99.4 66.0 60.9 54.6 17.9 71.5 298.0 224.4 133.8 113.3 22.5 149.1 64.3 95.9 112.9 148.1 110.3 18.8 197.7 77.9 565.8 144.8 360.9 17.8 81.8 76.1 126.0 127.4 81.6 18.7 497.0 151.2 130.1 112.7 130.6 28.5 22.3 71.7 69.8 215.3 18.5 13.8 212.7 154.6 119.3 383.6 18.8 93.8 140.2 220.5 15.0 289.8 73.6 46.4 10.6 17.4 540.2 536.6 120.7 139.0 426.2 482.1 180.0 101.6 20.9 92.1 79.7 120.5 24.5 29.2 291.0 341.3 440.3 62.9 35.7 227.4 413.2 CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 434.4;Distal tubular cells: 389.4;Hepatocytes: 353.6;Proximal enterocytes: 425.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" 66.9 55.3 22.1 28.0 24.4 58.4 32.8 26.0 26.5 34.0 24.7 113.8 85.4 21.8 34.1 74.5 20.8 48.1 53.2 30.3 32.9 76.1 185.1 52.7 18.6 32.9 31.0 19.1 42.2 54.1 21.6 26.3 35.8 34.3 81.9 20.5 49.9 27.5 81.0 45.5 70.0 27.6 26.9 20.2 112.7 10.7 33.3 20.1 49.8 86.5 41.1 44.8 41.3 28.4 72.4 72.7 28.3 109.0 120.4 113.8 41.0 56.2 69.1 44.8 48.0 66.6 140.4 12.6 59.8 77.7 47.7 89.0 56.0 83.9 51.5 44.8 20.0 50.8 58.1 103.6 93.5 66.5 73.7 116.7 98.8 51.9 53.3 68.0 82.1 37.9 81.2 79.5 52.5 43.5 27.7 72.5 29.0 118.4 35.9 35.9 46.2 34.0 92.5 144.1 17.4 44.3 96.4 178.2 48.7 49.9 101.0 66.3 108.3 47.5 50.3 76.9 36.7 45.0 131.6 59.4 84.9 42.2 44.1 255.5 227.6 274.8 49.5 204.4 51.5 40.2 46.2 50.0 152.1 33.0 29.1 41.4 173.3 56.5 207.4 95.1 60.7 116.5 22.1 24.4 26.0 26.5 30.3 32.9 32.9 31.0 35.8 26.9 33.3 28.4 28.3 44.8 117.3 20.9 26.8 72.3 62.4 48.1 20.5 11.0 101.6 39.2 80.5 243.1 50.7 103.0 10.4 33.3 38.3 434.4 389.4 96.7 52.5 68.0 48.8 39.5 55.6 58.5 24.8 150.6 62.4 38.2 112.7 114.4 37.4 18.9 78.1 353.6 68.5 11.8 21.0 136.2 34.6 170.1 134.8 122.6 29.5 77.1 129.9 19.7 113.4 32.7 36.0 9.5 23.6 173.9 206.4 29.3 24.0 80.1 425.0 231.1 33.7 10.3 26.3 46.6 41.4 13.7 19.3 50.6 108.5 66.9 32.9 65.7 161.4 130.8 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 344.4;Late spermatids: 650.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.9;eosinophil: 14.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favorable (7.41e-4)" "unprognostic (1.79e-1)" 39.8 47.7 48.6 17.7 49.1 62.0 102.9 43.8 65.6 50.5 41.9 49.4 88.1 19.2 56.1 24.9 33.4 40.2 91.3 46.1 47.3 73.5 157.4 38.4 20.0 50.0 51.2 18.7 25.0 92.4 12.4 22.8 44.9 35.0 48.9 4.8 130.0 50.0 27.8 28.0 75.7 18.8 50.0 23.5 56.0 28.1 54.4 9.0 38.0 28.3 21.2 32.4 26.2 48.9 11.3 51.2 13.7 29.3 106.6 35.7 38.9 40.2 46.2 39.7 25.5 19.3 7.7 17.3 22.1 55.1 54.3 16.9 83.8 14.2 37.3 26.2 70.1 69.7 25.7 112.6 59.4 34.8 13.5 33.6 4.1 18.0 32.7 59.0 20.0 36.4 102.8 43.1 39.4 27.6 20.8 118.5 36.2 53.8 67.4 15.9 26.8 12.4 17.9 43.4 13.8 10.4 37.2 52.3 103.2 21.4 53.8 23.6 14.7 36.1 18.7 28.5 39.9 24.3 7.9 21.2 28.4 39.7 53.4 36.9 2.2 14.6 0.6 1.7 0.6 4.4 1.2 0.9 2.9 2.6 0.4 0.6 3.1 4.6 2.2 3.7 0.6 0.5 48.6 49.1 43.8 65.6 46.1 47.3 50.0 51.2 44.9 50.0 54.4 48.9 27.1 48.1 27.6 159.6 135.1 37.5 313.3 4.2 21.6 19.3 243.8 76.7 45.3 102.9 13.1 64.4 29.2 123.9 32.6 61.7 70.5 8.1 344.4 17.1 50.2 22.5 21.1 168.6 95.8 13.8 56.1 75.4 69.8 21.0 10.8 15.3 31.1 189.7 56.4 35.3 95.6 53.4 2.0 102.9 55.7 650.9 85.4 81.2 145.9 36.5 27.0 68.1 5.2 65.9 10.2 9.6 113.3 89.1 55.4 172.1 174.1 183.7 4.3 16.0 19.7 88.2 37.8 193.8 43.2 43.1 43.2 60.3 41.3 3.4 90.7 291.6 CHRD ENSG00000090539 Chordin Q9H2X0 3 184380073-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 130.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 31.2;Excitatory neurons: 28.2;Fibroblasts: 16.4;Hepatocytes: 36.4;Inhibitory neurons: 37.5;Skeletal myocytes: 19.1;Smooth muscle cells: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 11.8;MCF7: 2.5;SuSa: 4.0;U-2 OS: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035827 Approved "Secreted in other tissues" NA NA 350000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 36: Stromal cells - Cell proliferation" "HPA035827: AB_10669657" "unprognostic (2.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.63e-2)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (6.55e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (5.53e-3)" "unprognostic (1.85e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-3)" 11.1 12.2 13.9 2.1 13.9 0.0 9.9 19.0 21.2 40.0 9.1 7.6 1.6 32.9 3.2 3.3 15.0 2.5 11.2 15.1 9.4 18.8 130.0 7.2 1.5 10.1 9.9 16.3 17.1 1.1 6.0 2.4 10.2 9.7 0.8 0.0 3.8 5.2 4.4 5.4 6.0 4.6 10.3 9.7 7.8 1.1 9.7 0.2 7.7 2.7 0.3 7.2 15.4 13.6 0.0 0.0 0.3 1.1 0.1 0.1 1.4 0.3 0.0 0.2 0.1 2.8 0.0 0.0 1.1 0.3 1.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 11.8 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 4.0 1.4 0.0 0.0 0.0 3.8 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 13.9 19.0 21.2 15.1 9.4 10.1 9.9 10.2 10.3 9.7 13.6 2.6 0.0 0.0 11.8 0.4 2.7 0.0 0.0 0.6 2.9 2.1 1.8 3.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 3.6 31.2 2.6 0.0 0.0 28.2 3.1 0.0 16.4 1.1 4.5 0.0 0.9 3.3 36.4 0.7 0.0 37.5 0.2 0.0 3.2 3.1 0.0 3.7 0.4 1.8 4.7 0.0 0.0 0.0 7.1 2.5 1.1 0.0 2.2 0.0 0.1 0.0 4.0 0.0 0.5 6.6 19.1 16.4 0.3 0.3 0.3 1.1 0.1 0.7 0.1 0.0 0.3 CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 27.0;prostate: 29.6;salivary gland: 28.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Breast myoepithelial cells: 3.6;Excitatory neurons: 8.7;Inhibitory neurons: 7.8;Intestinal goblet cells: 3.2;Melanocytes: 3.6;Oligodendrocyte precursor cells: 3.0;Prostatic glandular cells: 4.4" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 178 "amygdala: 12.4;basal ganglia: 18.7;cerebral cortex: 27.0;hippocampal formation: 22.6;white matter: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "MCF7: 3.7;OE19: 12.3" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" 0.0 3.3 12.4 0.3 18.7 0.0 2.7 0.0 27.0 0.0 0.0 0.8 0.4 0.1 0.0 0.3 0.2 0.1 0.1 22.6 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.2 0.0 29.6 0.7 0.1 28.8 0.0 0.0 2.8 0.7 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 12.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.4 0.1 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 18.7 0.0 27.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.0 0.0 1.8 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.8 3.2 0.0 0.0 0.3 0.0 0.0 0.0 3.6 1.0 0.0 0.0 0.0 3.0 1.0 0.0 0.1 0.0 0.0 4.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.1 CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904465-130186634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 509.1;Inhibitory neurons: 349.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 2.0;basal ganglia: 2.6;cerebral cortex: 2.9;hippocampal formation: 2.5;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.1;ASC TERT1: 11.5;HSkMC: 7.6;TIME: 7.4;U-138 MG: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA044612: AB_10795883" "unprognostic (3.43e-2)" "unprognostic (6.28e-3)" "unprognostic (1.76e-2)" "unprognostic (5.83e-2)" "unprognostic (5.88e-2)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (9.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.08e-6)" "unprognostic (5.22e-3)" "unprognostic (9.93e-2)" "unprognostic (4.61e-3)" "unprognostic (1.74e-2)" 6.0 0.5 2.0 1.0 2.6 0.0 2.8 0.0 2.9 4.5 0.0 0.7 0.5 1.5 0.1 0.6 1.1 2.8 1.3 2.5 0.2 0.2 1.7 1.8 0.5 0.0 0.4 0.3 0.3 0.4 0.3 2.2 0.0 0.5 0.5 1.0 0.5 0.6 1.0 1.3 0.5 2.0 0.2 0.7 0.5 0.7 0.4 0.2 1.2 0.5 0.4 1.7 1.9 1.1 0.0 0.1 1.2 0.0 13.1 11.5 1.0 3.0 0.1 0.4 0.4 0.0 0.1 0.0 0.3 4.6 0.0 0.0 0.0 0.1 0.0 0.0 1.6 1.9 5.6 0.5 1.2 0.0 0.0 7.6 0.0 0.1 1.2 0.6 3.2 0.0 0.0 1.9 5.2 0.0 0.0 0.0 0.7 0.0 1.2 0.4 5.7 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.3 1.1 0.2 0.5 7.4 14.2 3.0 0.2 2.0 0.0 0.0 0.0 0.3 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.6 0.0 2.9 2.5 0.2 0.0 0.4 0.0 0.2 0.4 1.1 2.0 9.6 1.1 20.2 0.0 0.5 0.0 0.0 1.2 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.9 0.5 14.8 2.4 0.0 0.0 509.1 0.0 0.1 2.9 0.0 0.3 0.0 4.1 3.6 1.8 1.9 0.0 349.5 0.0 0.0 1.3 0.7 0.1 1.2 0.1 3.6 87.1 0.0 1.3 0.0 76.9 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 6.6 0.9 6.3 1.6 0.7 0.3 0.3 0.4 0.2 0.6 0.0 0.1 CIBAR2 "FAM92B, FLJ44299" ENSG00000153789 "CBY1 interacting BAR domain containing 2" Q6ZTR7 16 85098358-85112472 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "fallopian tube: 85.5" "Cell type enriched" "Detected in single" 8 "Plasma cells: 2.4" "Group enriched" "Detected in some" 5 "endometrial cancer: 5.4;lung cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 2.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA041022 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA041022: AB_10795500" "unprognostic (1.77e-4)" "unprognostic (7.44e-3)" "unprognostic (1.61e-1)" "unprognostic (2.11e-3)" "unprognostic (5.09e-3)" "unprognostic (1.14e-3)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (9.81e-2)" "unprognostic (3.70e-1)" "unprognostic (3.84e-2)" "unprognostic (2.05e-1)" "unprognostic (5.10e-13)" "unprognostic (2.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.47e-1)" "unprognostic (1.29e-1)" 0.1 1.3 2.0 1.3 1.8 0.4 0.3 1.0 0.8 3.5 11.2 0.7 1.3 1.3 0.2 0.1 85.5 0.1 0.0 1.9 4.9 0.2 0.0 10.2 0.6 8.2 11.2 0.1 0.1 0.0 16.2 0.0 5.5 0.1 0.4 0.3 0.5 0.1 0.0 0.4 0.7 0.0 5.3 2.6 0.4 0.4 4.7 0.2 0.0 0.0 1.9 1.1 0.0 2.5 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 2.5 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 2.0 1.8 1.0 0.8 1.9 4.9 8.2 11.2 5.5 5.3 4.7 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CIDEA CIDE-A ENSG00000176194 "Cell death inducing DFFA like effector a" O60543 18 12254361-12277595 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "adipose tissue: 221.3;breast: 108.0" "Cell type enriched" "Detected in some" 78 "Breast glandular cells: 330.6" "Cancer enhanced" "Detected in some" "breast cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "hTEC/SVTERT24-B: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "unprognostic (2.96e-2)" "unprognostic (2.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (8.93e-3)" "unprognostic (3.20e-2)" "unprognostic (7.00e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-3)" "unprognostic (3.17e-2)" "unprognostic (7.67e-3)" "unprognostic (1.96e-1)" 221.3 3.7 2.3 0.2 3.2 0.0 108.0 2.8 5.2 3.5 1.7 1.5 0.0 0.0 0.0 4.8 0.0 1.2 1.9 2.7 1.8 0.2 0.2 0.0 0.3 2.4 2.2 0.0 0.9 0.0 0.0 0.0 2.7 0.1 0.9 0.1 4.3 0.0 1.0 9.3 2.1 0.2 2.2 0.0 1.0 0.1 2.0 0.2 0.5 4.6 0.2 1.1 5.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.8 5.2 2.7 1.8 2.4 2.2 2.7 2.2 2.0 3.0 1.9 0.0 0.0 0.7 0.5 0.1 0.1 0.3 0.0 0.2 330.6 3.8 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 1.0 0.0 0.2 0.3 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.2 0.6 0.6 1.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.4 0.3 0.7 1.0 0.0 0.3 0.5 0.0 0.8 CIDEC "CIDE-3, FLJ20871, Fsp27" ENSG00000187288 "Cell death inducing DFFA like effector c" Q96AQ7 3 9866711-9880255 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 740.3;breast: 492.9" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 219.4" "Group enriched" "Detected in many" 5 "breast cancer: 4.5;colorectal cancer: 1.4;liver cancer: 2.4;pancreatic cancer: 4.6;stomach cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 1683.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018837, HPA020553" Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA018837: AB_1846767, HPA020553: AB_1846769" "unprognostic (1.83e-2)" "unprognostic (3.08e-2)" "unprognostic (2.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-1)" "unprognostic (7.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-5)" "unprognostic (9.03e-2)" "unprognostic (1.81e-1)" "unprognostic (5.48e-3)" "unprognostic (8.14e-2)" "unprognostic (5.37e-5)" "unprognostic (9.47e-3)" "unprognostic (2.02e-1)" "unprognostic (7.46e-3)" "unprognostic (2.94e-2)" 740.3 5.6 0.1 1.1 0.2 0.0 492.9 0.0 0.4 1.2 0.0 15.9 68.9 4.6 0.3 0.7 2.2 5.0 9.5 0.1 0.1 2.1 10.0 0.2 1.2 0.1 0.2 0.4 7.4 0.1 0.2 0.0 0.2 2.3 3.9 0.0 16.2 3.7 6.1 18.1 89.8 1.6 0.1 0.2 7.4 0.9 0.2 1.5 3.9 11.6 0.0 13.3 4.8 0.2 0.0 0.2 0.0 0.0 1683.2 376.0 1.2 0.1 0.0 0.0 0.0 7.5 9.1 0.0 0.2 0.6 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 19.1 2.8 0.0 0.0 228.9 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.3 0.0 0.6 1.6 0.0 0.0 1.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 2.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 2.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 30.0 1.9 0.0 0.5 0.2 0.1 0.1 3.5 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 8.4 0.0 0.0 0.4 1.0 2.5 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 14.5 0.4 0.0 0.4 219.4 1.1 0.0 0.0 0.0 0.5 0.6 0.6 0.4 0.0 0.0 0.0 0.2 0.1 3.8 0.3 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CISD3 "Miner2, MiNT" ENSG00000277972 "CDGSH iron sulfur domain 3" P0C7P0 17 38730341-38735605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal enterocytes: 454.6;Hepatocytes: 673.4;Paneth cells: 406.2;Proximal enterocytes: 715.7;Proximal tubular cells: 500.6;Undifferentiated cells: 398.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 5.3;U-138 MG: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053436, HPA054400" Approved NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" "HPA053436: AB_2682149, HPA054400: AB_2682475" "unprognostic (9.42e-2)" "unprognostic (8.73e-2)" "unprognostic (7.64e-2)" "unprognostic (2.38e-2)" "unprognostic (2.75e-1)" "unprognostic (1.50e-2)" "unprognostic (1.32e-1)" "unprognostic (4.81e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" "unprognostic (2.88e-2)" "unprognostic (1.31e-2)" "unprognostic (2.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.42e-1)" 13.1 18.0 0.4 0.1 0.0 0.0 13.5 0.9 0.7 9.7 0.2 14.7 1.4 11.1 0.4 8.2 11.0 1.4 23.8 0.1 0.2 17.8 24.8 8.6 0.3 0.4 1.2 8.0 19.4 0.1 7.8 1.3 0.6 11.1 0.1 0.6 8.4 0.2 13.3 9.0 12.9 0.1 0.1 7.9 14.8 4.7 0.3 0.0 11.9 0.0 0.0 12.1 8.8 0.0 0.8 1.5 1.6 5.3 0.0 0.1 1.0 0.7 0.0 0.2 0.0 0.4 4.3 0.0 0.1 0.0 3.5 3.7 0.1 0.1 0.4 0.2 0.0 0.6 0.5 1.2 0.2 0.0 2.3 0.1 0.0 0.1 0.0 1.6 0.1 4.8 0.4 1.4 0.2 0.0 0.9 0.0 5.1 0.0 1.2 1.6 0.0 0.3 0.1 0.8 0.8 2.7 1.0 0.7 3.8 0.0 4.3 0.9 0.0 6.5 4.0 4.1 2.8 0.6 0.1 0.5 2.0 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.7 0.1 0.2 0.4 1.2 0.6 0.1 0.3 0.0 58.6 19.2 23.6 6.2 21.4 26.5 41.4 27.3 22.8 20.0 92.6 86.5 261.4 175.8 29.6 62.5 14.6 26.1 44.7 454.6 205.4 102.1 2.2 34.8 35.8 41.9 129.0 45.5 5.3 241.4 52.3 41.8 111.1 29.1 31.8 34.6 43.9 673.4 136.7 6.7 3.9 262.5 16.2 87.4 47.9 7.0 45.7 58.3 55.2 1.9 73.3 36.7 165.8 2.0 4.9 152.6 406.2 47.8 24.0 95.0 715.7 500.6 21.5 15.2 59.2 31.8 72.2 8.8 31.4 70.9 35.9 13.1 47.2 53.1 398.5 51.5 CITED1 MSG1 ENSG00000125931 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1" Q99966 X 72301638-72307187 "Predicted intracellular proteins" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "epididymis: 1473.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 87.4;Breast myoepithelial cells: 47.6;Granulosa cells: 31.0;Late spermatids: 58.4;Paneth cells: 33.8" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 134.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 244.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049051 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA049051: AB_2680612" "unprognostic (7.04e-2)" "unprognostic (3.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-3)" "unprognostic (8.81e-2)" "unprognostic (5.67e-4)" "unprognostic (3.40e-1)" "unprognostic (9.55e-2)" "unprognostic (4.60e-3)" "unprognostic (4.38e-2)" "unprognostic (6.33e-3)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.62e-1)" "prognostic favorable (6.10e-4)" "prognostic favorable (3.95e-4)" "unprognostic (2.99e-2)" 2.3 5.1 13.0 0.3 6.9 0.2 23.1 5.1 12.2 5.9 3.4 1.0 0.7 3.6 1473.6 0.3 1.5 0.0 0.7 6.7 56.2 5.1 0.4 0.6 0.3 8.5 8.8 1.5 1.5 0.0 209.9 0.0 24.5 11.2 0.2 4.5 0.8 3.0 0.4 0.6 1.0 8.1 4.3 0.4 1.0 199.9 30.6 0.2 8.0 0.4 0.1 0.5 1.0 6.2 0.4 0.3 2.2 57.1 2.5 0.0 2.1 0.0 0.5 0.4 0.3 0.1 0.6 0.0 0.2 0.0 0.6 0.0 20.5 1.4 0.1 6.1 8.0 0.9 0.4 0.0 0.0 0.2 10.4 1.1 0.8 0.5 1.0 0.2 0.2 0.2 2.5 0.0 0.4 0.8 0.2 4.4 3.3 0.0 3.6 0.1 3.6 3.2 0.1 0.4 25.8 12.5 0.4 5.1 244.4 0.2 1.4 1.0 0.0 0.2 1.9 0.4 0.8 0.2 0.5 0.2 0.5 0.4 5.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 6.9 5.1 12.2 6.7 56.2 8.5 8.8 24.5 4.3 30.6 6.2 2.2 0.0 0.0 0.0 0.0 0.1 1.0 0.4 0.0 5.6 87.4 47.6 0.4 1.5 0.1 3.7 6.2 0.1 0.3 0.3 0.0 0.1 20.4 0.5 0.8 1.0 1.2 0.0 0.7 0.8 0.1 0.7 0.0 0.3 0.0 31.0 0.4 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.7 58.4 7.5 0.8 3.6 1.9 0.1 1.7 0.0 0.0 0.1 0.4 33.8 3.0 0.0 19.3 0.7 0.3 0.0 3.8 13.1 1.2 3.2 12.6 6.8 0.0 0.0 0.0 0.1 0.5 0.5 1.0 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 694.7;intestine: 653.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 2767.4;Distal enterocytes: 4691.8;Distal tubular cells: 2281.3;Horizontal cells: 5042.4;Muller glia cells: 3639.8;Rod photoreceptor cells: 3789.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 290.8" "Lineage enriched" "Detected in many" 18 "monocytes: 290.8" "Cell line enhanced" "Detected in many" "CACO-2: 455.8;HEK 293: 1399.8;SCLC-21H: 792.2;SH-SY5Y: 352.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favorable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 90.7 60.0 471.6 25.8 627.0 3.2 47.2 641.1 694.7 105.2 192.7 653.4 36.0 222.6 16.0 54.5 197.9 17.9 269.8 428.7 482.3 161.0 9.0 60.3 4.0 427.5 440.4 58.8 27.7 108.2 74.0 4.7 345.1 301.8 151.9 471.3 37.9 208.3 80.0 76.5 120.8 113.8 434.5 6.8 479.9 97.6 596.2 2.8 87.9 47.1 5.1 298.4 101.6 383.6 2.4 54.5 321.1 14.7 4.4 2.3 6.3 37.5 0.3 2.4 1.4 455.8 7.3 0.4 36.9 29.1 9.9 70.2 109.9 1.5 0.2 9.6 1399.8 111.0 242.1 165.4 16.6 0.7 87.9 14.7 0.6 3.9 0.8 3.3 0.0 5.1 198.7 3.7 4.8 20.0 2.3 3.9 109.1 48.3 213.6 13.9 6.8 275.9 65.9 2.5 792.2 352.2 65.3 10.6 25.2 21.6 21.1 40.9 2.2 1.5 56.3 4.7 147.3 21.1 2.7 7.2 6.4 2.1 14.1 2.4 0.5 14.6 0.3 28.5 0.4 0.0 0.2 0.1 16.4 0.2 0.1 0.5 1.0 0.2 290.8 0.0 0.7 6.0 471.6 627.0 641.1 694.7 428.7 482.3 427.5 440.4 345.1 434.5 596.2 383.6 14.8 195.5 103.5 515.8 13.5 153.7 296.2 257.6 56.3 2767.4 41.5 48.9 553.5 145.8 117.9 114.0 1909.9 4.4 3.4 4691.8 2281.3 127.6 445.8 773.2 205.7 60.8 467.1 9.9 178.0 42.5 11.7 96.6 359.4 408.5 28.6 476.1 74.6 9.2 8.2 5042.4 147.0 726.0 187.2 2.8 44.9 147.4 304.1 39.8 181.5 88.1 74.2 3639.8 0.0 93.5 161.2 131.4 1996.9 1089.3 6.6 279.8 9.5 118.0 456.1 3789.9 59.2 15.4 222.6 127.3 97.4 22.1 175.2 41.6 19.1 12.2 755.6 220.1 CLDN2 ENSG00000165376 "Claudin 2" P57739 X 106900164-106930861 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 114.7;gallbladder: 101.6;kidney: 165.2;seminal vesicle: 90.1" "Cell type enhanced" "Detected in some" "Ductal cells: 77.5;Exocrine glandular cells: 49.1;Hepatocytes: 25.9;Pancreatic endocrine cells: 30.9;Proximal enterocytes: 32.9;Proximal tubular cells: 153.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 53.3;liver cancer: 24.6;pancreatic cancer: 48.5;renal cancer: 87.2;stomach cancer: 30.5" "Region enriched" "Detected in some" 5 "hippocampal formation: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 296.4" "Group enriched" "Detected in many" 4 "basal ganglia: 4.5;hippocampal formation: 9.5;pons and medulla: 10.3;thalamus: 8.9" "Region enhanced" "Detected in some" "medulla oblongata: 1.7" "CAB002609, HPA051548" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cell Junctions" "CAB002609: , HPA051548: AB_2681530" "unprognostic (2.31e-1)" "unprognostic (2.62e-1)" "unprognostic (3.99e-1)" "unprognostic (1.73e-1)" "unprognostic (1.30e-2)" "unprognostic (1.42e-2)" "unprognostic (6.07e-2)" "unprognostic (7.47e-3)" "unprognostic (2.24e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (8.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "prognostic favorable (1.70e-4)" "unprognostic (9.76e-2)" 0.7 3.0 0.1 2.2 0.1 0.1 0.6 1.6 0.5 0.0 114.7 2.1 21.0 0.1 33.7 0.1 0.3 101.6 0.0 8.4 0.0 165.2 44.2 1.3 0.0 0.2 0.2 0.0 13.2 0.0 0.2 0.0 0.1 1.2 4.5 0.7 0.1 90.1 0.2 0.3 24.5 0.2 0.0 0.0 7.7 0.0 1.3 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 27.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 296.4 0.2 0.0 0.0 0.1 46.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.5 8.4 0.0 0.2 0.2 0.1 0.0 1.3 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 14.3 0.0 1.8 0.0 0.0 0.0 0.3 15.6 77.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 49.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 25.9 0.0 0.0 0.3 2.7 0.0 0.8 0.0 1.4 0.0 0.7 0.0 0.0 1.6 1.6 0.0 1.0 0.2 30.9 3.6 0.0 0.0 0.0 32.9 153.1 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 14.2 0.0 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CLEC1A "CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.2;placenta: 49.0" "Cell type enhanced" "Detected in some" "Adipocytes: 51.4;Cytotrophoblasts: 51.5;Endothelial cells: 38.1;Extravillous trophoblasts: 61.7;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 21.3;HUVEC TERT2: 18.3;SuSa: 5.6;U-266/70: 4.9;U-266/84: 11.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" 16.2 3.2 4.4 4.1 4.2 0.4 14.8 6.6 5.6 11.4 4.1 4.3 1.5 6.8 2.7 3.8 9.2 5.7 9.0 3.9 3.8 5.8 2.9 29.8 5.9 4.8 4.5 5.4 2.3 1.6 3.7 49.0 4.7 6.3 2.0 0.6 2.9 2.4 3.9 4.1 4.4 8.7 4.3 8.0 3.7 2.1 5.1 50.2 7.6 4.4 3.5 6.1 8.6 4.1 0.0 0.0 0.3 0.3 0.2 0.2 21.3 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.9 0.0 0.0 0.0 0.4 3.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.4 0.0 0.3 0.3 0.0 5.6 0.0 0.0 1.4 0.0 0.2 0.2 0.0 4.9 11.5 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 4.4 4.2 6.6 5.6 3.9 3.8 4.8 4.5 4.7 4.3 5.1 4.1 51.4 0.0 0.5 0.0 0.5 2.2 0.1 0.0 1.2 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 51.5 0.2 0.0 0.0 0.0 0.4 0.0 0.1 38.1 0.0 0.0 0.0 0.0 61.7 1.2 0.0 0.0 0.0 0.0 16.8 0.2 5.0 0.0 0.0 0.0 0.0 4.7 14.1 0.6 7.5 4.0 3.6 11.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.9 4.0 2.9 0.3 1.6 52.1 0.6 0.3 0.0 0.5 CLEC4G "LSECtin, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728958-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 14.9;liver: 53.3;lymphoid tissue: 15.1" "Cell type enriched" "Detected in some" 15 "Hepatic stellate cells: 730.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.1" "Group enriched" "Detected in many" 4 "dendritic cells: 15.1;monocytes: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" 14.9 0.5 1.9 2.4 1.9 1.2 2.6 4.0 2.9 0.1 2.0 1.4 0.4 0.1 0.3 0.4 4.8 1.6 1.2 2.5 1.9 0.5 53.3 1.0 15.1 2.3 2.1 0.5 0.3 0.0 0.1 1.0 2.1 0.3 0.9 0.0 1.1 0.3 0.4 1.1 2.0 1.0 2.1 3.4 0.9 0.4 4.3 0.2 0.5 0.0 0.3 7.7 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.8 0.0 0.0 4.2 0.0 0.3 0.0 0.0 15.1 4.2 0.1 0.0 0.4 0.5 0.5 0.7 0.0 4.5 1.9 1.9 4.0 2.9 2.5 1.9 2.3 2.1 2.1 2.1 4.3 2.1 0.1 0.0 0.0 0.3 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 18.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 730.3 7.1 0.8 0.0 1.1 0.0 0.0 46.7 2.9 0.0 0.3 2.6 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.7 0.0 0.3 0.3 1.1 0.8 0.0 0.1 CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.3;Early spermatids: 162.4;Endometrial ciliated cells: 93.4;Muller glia cells: 176.4;Spermatocytes: 465.5" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 53.0;MOLT-4: 47.8;U-251 MG: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" 0.4 6.6 0.9 1.0 0.7 2.4 2.7 3.8 1.6 0.9 2.0 2.6 0.5 1.6 0.6 1.2 13.7 0.4 59.5 0.9 2.6 0.4 3.2 0.5 0.7 2.7 1.9 0.3 2.2 0.6 11.2 0.2 2.6 22.5 1.3 17.2 1.0 0.7 0.4 0.2 1.3 1.5 1.2 0.2 2.0 113.6 2.3 2.4 2.7 1.6 1.2 0.6 0.1 0.9 0.2 10.2 10.3 6.9 4.0 21.1 2.4 0.1 9.4 10.0 18.6 0.3 0.9 0.0 27.8 0.9 8.4 0.2 7.5 0.1 16.2 0.4 9.0 3.0 9.8 7.4 41.4 38.9 0.6 2.2 39.2 1.0 0.9 53.0 0.2 9.6 2.0 0.0 0.0 0.5 47.8 0.5 12.0 0.2 28.1 31.5 0.0 0.4 0.0 0.3 16.8 29.8 6.5 4.1 1.8 3.8 1.9 5.6 0.0 27.4 4.7 9.7 73.6 14.4 31.7 19.9 43.4 1.6 2.9 0.9 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 3.8 1.6 0.9 2.6 2.7 1.9 2.6 1.2 2.3 0.9 0.8 0.0 2.2 0.3 0.1 0.0 0.9 8.5 1.2 9.2 3.3 1.8 313.3 0.0 6.4 0.0 4.2 0.5 0.0 0.5 0.0 1.2 162.4 93.4 1.3 11.9 5.3 8.6 7.2 4.2 0.1 10.2 0.0 11.3 0.0 10.1 0.7 3.7 0.1 25.2 6.7 0.4 30.5 0.0 0.0 60.2 5.0 0.7 1.8 0.0 0.1 176.4 0.0 6.6 0.6 0.9 3.9 4.5 0.1 33.8 0.2 0.1 24.6 16.3 0.0 0.6 2.0 465.5 23.9 2.8 0.1 0.3 0.7 0.2 0.8 1.3 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.7;skeletal muscle: 289.7;tongue: 98.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 509.6;Cardiomyocytes: 285.7;Distal enterocytes: 164.2;Late spermatids: 93.8;Proximal enterocytes: 126.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;EFO-21: 9.2;HDLM-2: 4.7;REH: 11.9;U-266/70: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" 18.9 1.5 3.2 4.3 4.4 0.2 6.5 1.5 2.9 19.0 0.5 28.6 20.9 2.1 0.9 2.9 4.5 3.0 102.7 2.1 5.0 54.7 0.3 70.8 1.7 2.1 3.8 0.5 1.1 1.7 3.0 16.5 2.2 2.6 25.8 16.9 2.7 1.4 289.7 1.2 36.6 2.3 1.8 44.5 1.6 1.4 5.5 1.0 7.3 98.3 1.9 2.0 2.6 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 13.5 0.0 9.2 0.0 0.0 0.3 0.0 0.1 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.4 1.6 0.0 11.9 0.3 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 12.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.1 0.1 2.0 1.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.5 3.2 4.4 1.5 2.9 2.1 5.0 2.1 3.8 2.2 1.8 5.5 1.9 59.6 509.6 30.0 4.6 1.4 0.1 0.1 0.0 1.2 0.3 0.5 0.4 285.7 5.7 26.9 14.7 0.0 0.2 0.7 164.2 0.0 1.7 52.9 4.6 0.5 29.8 13.1 0.4 8.6 0.2 0.1 7.9 0.5 5.7 1.3 0.0 0.7 0.0 0.0 0.0 5.4 23.5 0.0 0.0 0.0 93.8 0.9 0.7 0.0 34.7 0.6 53.8 0.0 0.5 2.9 2.9 51.1 0.7 3.4 3.2 126.0 2.9 11.4 1.8 0.0 6.1 4.3 1.0 0.1 0.1 0.1 2.2 5.8 0.1 13.5 4.3 CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.7;Fibroblasts: 95.1;Inhibitory neurons: 31.9;Peritubular cells: 57.9;Skeletal myocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 124.8;BJ: 171.8;BJ hTERT+: 160.3;fHDF/TERT166: 126.6;hTEC/SVTERT24-B: 129.1;hTERT-HME1: 155.6;U-138 MG: 232.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" 63.2 6.5 0.9 14.7 0.8 0.4 24.5 7.8 2.7 20.5 3.6 41.1 7.3 30.3 4.3 10.1 18.4 23.1 12.9 5.3 0.4 6.0 0.4 8.1 7.4 4.2 2.1 9.1 2.0 0.2 1.9 26.3 1.8 7.4 10.6 0.9 5.4 8.5 1.7 6.5 17.3 36.3 2.0 8.1 16.0 2.6 2.1 0.8 2.4 3.4 5.0 16.7 14.0 5.2 3.0 3.3 7.5 15.2 124.8 108.1 45.5 171.8 160.3 23.9 43.8 7.4 0.2 0.0 0.4 126.6 82.4 0.1 0.3 45.5 27.3 0.9 0.3 0.0 7.1 0.1 40.7 0.0 0.1 61.0 30.6 129.1 155.6 59.7 11.7 0.1 0.0 0.4 33.3 0.1 0.0 0.2 17.4 0.0 20.2 0.1 2.5 0.1 12.6 0.0 20.5 50.3 0.0 0.4 0.1 3.2 0.6 0.0 43.3 232.7 2.3 96.0 21.6 0.1 0.0 0.1 63.1 0.0 7.5 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.9 0.8 7.8 2.7 5.3 0.4 4.2 2.1 1.8 2.0 2.1 5.2 2.3 0.0 3.9 2.0 0.2 1.5 0.3 2.4 0.0 3.8 1.2 14.6 5.1 0.0 0.4 0.0 0.0 9.8 0.3 0.1 0.0 1.9 0.7 2.4 75.7 1.4 6.7 0.0 26.5 1.3 20.4 95.1 0.0 1.4 0.0 5.3 2.2 0.0 3.6 1.7 31.9 0.5 0.0 0.0 1.9 0.7 20.8 0.9 0.0 4.7 0.0 0.5 0.0 1.0 3.6 0.9 0.0 57.9 0.6 2.0 0.1 0.1 0.2 1.1 0.0 65.0 8.5 0.1 0.1 0.4 1.0 10.4 1.1 2.2 0.3 0.5 CLN3 "BTN1, BTS, JNCL" ENSG00000188603 "CLN3 lysosomal/endosomal transmembrane protein, battenin" Q13286 16 28474111-28495575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 315.9;Extravillous trophoblasts: 106.9;Syncytiotrophoblasts: 451.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 178.0;SK-BR-3: 186.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063280 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA063280: AB_2684975" "unprognostic (2.38e-3)" "unprognostic (2.41e-2)" "unprognostic (7.06e-2)" "unprognostic (8.83e-2)" "unprognostic (1.04e-1)" "unprognostic (1.68e-1)" "unprognostic (2.36e-2)" "unprognostic (1.69e-2)" "unprognostic (6.38e-3)" "unprognostic (8.16e-2)" "unprognostic (6.27e-2)" "unprognostic (5.26e-1)" "unprognostic (9.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.05e-2)" 18.1 30.5 13.1 19.6 14.2 13.4 21.4 14.2 16.0 16.9 16.5 38.3 21.9 15.9 9.9 22.2 16.0 15.2 11.7 13.2 13.6 21.2 31.9 23.6 13.8 14.6 13.6 16.8 27.7 30.0 8.2 36.9 15.1 17.3 29.2 3.1 34.5 21.0 14.5 24.1 25.7 13.3 13.5 20.4 26.1 7.9 15.6 14.0 24.7 13.8 12.1 19.3 15.6 17.1 23.1 39.2 15.4 38.4 41.1 19.9 178.0 14.8 40.7 28.3 34.9 19.7 52.9 16.0 45.8 24.8 52.0 23.5 25.8 24.7 12.9 38.0 38.5 15.6 24.1 60.6 60.5 23.3 64.7 28.0 66.8 21.9 14.7 26.3 32.9 24.9 30.9 55.0 28.8 61.9 20.7 45.1 21.8 35.3 26.0 37.2 13.4 54.5 30.2 53.0 20.8 19.6 5.7 186.5 18.3 14.0 62.2 32.4 20.2 19.2 10.1 24.9 22.5 58.3 64.2 15.9 28.4 47.3 11.9 63.4 59.8 98.4 57.6 47.6 42.7 24.3 43.6 53.6 63.8 29.3 38.3 40.6 23.8 41.2 38.7 68.1 53.5 46.6 13.1 14.2 14.2 16.0 13.2 13.6 14.6 13.6 15.1 13.5 15.6 17.1 1.2 22.4 15.9 11.1 10.8 0.1 17.2 0.0 23.9 10.9 1.7 0.6 0.0 38.6 6.2 1.8 12.5 315.9 25.8 46.4 0.0 2.2 1.1 1.8 1.3 11.2 17.0 17.5 7.5 0.5 106.9 9.3 20.9 2.6 2.5 7.6 21.0 39.0 70.1 13.5 8.1 39.3 0.0 36.7 0.4 2.5 19.0 17.7 0.0 2.8 17.5 25.0 40.2 7.1 11.4 1.5 43.7 12.4 13.1 10.6 53.1 0.8 1.5 12.1 13.1 9.9 3.5 3.2 8.4 17.1 0.1 451.4 15.9 3.6 50.2 13.3 CLNK MIST ENSG00000109684 "Cytokine dependent hematopoietic cell linker" Q7Z7G1 4 10486395-10684768 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.2" "Cell type enriched" "Detected in many" 5 "Ionocytes: 73.2" "Cancer enriched" "Detected in single" 13 "renal cancer: 3.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "HDLM-2: 4.1;U-937: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035671, HPA035672" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA035671: AB_10669673, HPA035672: AB_10669775" "unprognostic (2.47e-3)" "unprognostic (4.74e-4)" "unprognostic (1.99e-4)" "unprognostic (2.24e-3)" "unprognostic (1.17e-1)" "unprognostic (2.23e-6)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" "unprognostic (9.87e-2)" "unprognostic (3.75e-2)" "unprognostic (2.55e-1)" "unprognostic (7.74e-3)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (6.65e-3)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" 0.3 0.2 0.5 0.9 0.4 0.4 0.6 1.5 0.7 0.2 0.5 0.3 0.6 0.4 1.2 0.4 0.2 0.5 0.2 0.5 0.5 6.2 0.9 0.6 3.0 0.4 0.2 0.4 0.1 0.1 1.3 1.0 0.5 0.4 0.4 0.3 0.5 0.3 0.2 0.8 0.9 0.1 0.1 1.5 1.1 0.8 0.5 1.4 0.3 0.0 2.0 0.3 0.0 0.9 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 2.2 0.1 0.5 0.1 0.2 0.2 0.1 0.1 1.4 0.4 0.1 2.6 1.1 0.1 0.1 0.4 2.0 0.0 0.6 1.8 0.2 0.5 0.4 1.5 0.7 0.5 0.5 0.4 0.2 0.5 0.1 0.5 0.9 0.1 3.2 3.0 1.0 12.9 0.8 0.8 0.0 0.0 1.3 0.3 0.3 0.7 0.0 0.9 0.0 2.1 0.3 4.6 0.1 13.7 0.0 5.3 0.7 0.2 0.4 0.0 5.3 1.7 0.0 2.2 0.5 0.5 0.9 11.4 0.2 0.7 0.3 0.3 0.0 1.6 0.2 73.2 1.9 5.5 5.4 0.3 3.5 1.8 1.9 0.5 0.4 0.0 1.0 0.7 0.1 0.0 2.2 1.1 0.7 0.0 0.2 0.2 1.0 0.0 1.1 0.5 1.9 0.8 0.0 0.4 0.1 6.0 1.3 0.0 0.7 CLPSL1 "C6orf127, dJ510O8.6" ENSG00000204140 "Colipase like 1" A2RUU4 6 35781019-35793675 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 90 "epididymis: 607.6;pancreas: 178.4" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 39.0" "Group enriched" "Detected in some" 6 "breast cancer: 3.6;cervical cancer: 1.0;endometrial cancer: 2.8;ovarian cancer: 1.8;pancreatic cancer: 3.4" "Group enriched" "Detected in many" 4 "amygdala: 1.1;basal ganglia: 2.5;cerebral cortex: 2.3;hippocampal formation: 2.9;white matter: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "T-47d: 8.4" HPA073155 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA073155: AB_2686576" "unprognostic (7.97e-2)" "unprognostic (1.58e-1)" "unprognostic (4.75e-1)" "unprognostic (2.54e-1)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.60e-2)" "unprognostic (7.06e-3)" 0.1 0.3 1.1 0.0 2.5 0.0 4.3 0.3 2.3 0.0 0.2 0.0 0.0 0.0 607.6 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.1 178.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.5 2.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 8.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.5 0.3 2.3 2.9 0.3 0.3 0.4 0.3 0.3 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 39.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CLPSL2 "C6orf126, dJ510O8.5, UNQ3045" ENSG00000196748 "Colipase like 2" Q6UWE3 6 35776594-35779552 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 532.1" "Group enriched" "Detected in some" 4 "Breast glandular cells: 3.4;Breast myoepithelial cells: 2.2;Enteroendocrine cells: 1.8;Exocrine glandular cells: 4.0;Pancreatic endocrine cells: 2.1;Spermatogonia: 2.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "T-47d: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA051655 Approved "Secreted in male reproductive system" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA051655: " "unprognostic (2.38e-1)" "unprognostic (3.65e-1)" "unprognostic (6.39e-3)" "unprognostic (9.38e-2)" "unprognostic (4.03e-2)" "unprognostic (2.47e-1)" "unprognostic (4.85e-3)" "unprognostic (8.69e-2)" "unprognostic (3.17e-2)" "unprognostic (3.95e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.2 0.8 0.0 0.2 0.0 0.0 0.0 532.1 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.0 5.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.7 0.7 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.7 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.3 0.0 0.1 6.3 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.4 0.2 0.8 0.6 0.4 0.2 0.4 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 2.2 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.2 4.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Cone photoreceptor cells: 14.6;Early spermatids: 19.3;Late spermatids: 17.0;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.5;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Cell line enhanced" "Detected in many" "HMC-1: 64.8;K-562: 31.8" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 6.8 16.0 5.4 0.8 6.1 15.6 4.8 6.2 6.5 5.0 5.0 2.4 0.5 3.1 1.6 3.6 3.8 1.2 14.8 5.2 7.8 3.2 6.5 3.0 0.7 7.4 8.6 3.6 2.5 2.1 13.4 1.5 8.5 5.2 1.0 2.0 3.9 0.8 187.4 4.1 1.8 1.7 5.7 3.5 2.8 47.2 9.1 3.9 8.0 61.3 0.5 2.8 3.7 6.9 4.5 4.6 3.0 4.9 10.8 5.9 1.4 3.1 3.3 4.2 6.3 1.7 1.4 1.9 0.4 7.0 3.3 1.5 4.7 8.5 3.5 0.3 4.6 0.2 4.4 5.3 5.5 6.5 64.8 25.0 7.0 7.8 10.9 12.5 2.7 2.4 31.8 1.7 10.0 3.6 0.6 22.4 3.8 18.1 2.8 2.4 24.2 0.1 3.4 1.8 6.9 1.2 6.6 4.1 0.4 3.6 8.9 27.1 0.8 7.6 15.5 4.2 5.2 3.1 8.4 0.8 4.5 17.4 1.6 0.0 2.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.4 5.4 6.1 6.2 6.5 5.2 7.8 7.4 8.6 8.5 5.7 9.1 6.9 1.4 3.2 0.5 9.4 0.1 0.6 0.5 1.0 1.2 2.4 0.7 0.3 11.3 1.5 1.8 0.0 14.6 0.4 0.2 1.2 0.0 0.8 19.3 1.2 1.9 0.9 0.0 0.8 4.5 0.0 0.2 1.4 1.5 1.4 0.0 3.5 1.1 2.4 0.3 0.0 8.9 1.3 6.1 1.0 0.7 17.0 2.5 0.5 0.0 4.7 1.3 1.5 0.0 12.5 12.5 1.2 0.8 4.1 0.1 1.3 0.2 1.3 1.0 2.0 0.0 2.6 4.5 14.5 4.7 1.0 0.9 1.1 0.1 6.2 0.9 0.0 CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in some" "dendritic cells: 17.3;Hofbauer cells: 32.4;Kupffer cells: 69.6;Macrophages: 27.1;Microglial cells: 39.4;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.5;plasmacytoid DC: 18.1" "Group enriched" "Detected in many" 22 "dendritic cells: 18.1;monocytes: 14.5;T-cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 11.9;ASC TERT1: 45.3;BJ hTERT+: 34.9;hTERT-RPE1: 13.6;LHCN-M2: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" 10.4 5.9 3.3 11.7 3.0 0.9 4.9 2.5 3.2 4.7 4.2 7.5 4.5 8.3 1.6 3.1 4.4 5.5 6.4 2.6 4.9 3.3 6.9 12.8 17.6 5.9 4.7 1.9 3.2 1.7 3.4 22.2 5.3 3.8 8.9 0.3 4.7 4.5 2.4 4.2 5.1 14.7 4.0 34.3 2.8 2.6 5.9 4.2 8.7 5.1 8.1 8.1 2.5 7.5 0.0 0.0 0.1 0.0 11.9 45.3 0.2 0.0 34.9 0.1 0.0 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.2 13.6 0.7 0.0 0.0 0.0 10.6 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.9 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 4.1 0.0 7.0 14.5 0.0 0.0 1.1 5.1 1.1 0.0 0.4 3.5 0.3 0.6 2.8 18.1 0.3 5.1 3.3 3.0 2.5 3.2 2.6 4.9 5.9 4.7 5.3 4.0 5.9 7.5 1.9 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.1 0.3 2.2 1.5 0.6 0.0 0.0 0.4 17.3 0.0 0.0 0.0 0.1 0.0 0.7 5.8 0.0 2.7 0.5 0.0 0.5 7.8 0.0 0.0 0.0 0.0 11.4 0.6 32.4 0.0 0.4 0.0 0.0 69.6 2.5 0.3 0.3 27.1 3.6 39.4 7.6 0.0 30.9 1.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.7 0.1 6.6 4.1 5.1 0.0 0.0 0.1 0.6 0.5 2.2 0.5 0.0 0.0 CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 222.1;Granulosa cells: 140.8;Hofbauer cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 164.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" 49.3 16.6 15.5 25.0 14.3 20.0 32.8 15.6 28.1 40.2 9.5 16.8 7.1 30.4 16.6 10.4 25.5 32.7 26.2 15.6 18.0 19.7 10.7 35.4 32.3 24.9 15.8 38.9 7.9 29.4 10.1 44.4 19.3 23.4 12.1 3.0 17.4 16.7 6.4 22.2 18.8 27.7 17.0 36.1 11.9 59.7 19.1 35.5 16.1 13.0 20.9 34.3 26.7 20.4 6.7 33.8 93.4 66.2 68.4 42.6 59.2 17.5 78.6 34.4 34.0 18.6 21.0 0.2 47.7 49.0 59.7 7.8 63.7 57.4 27.3 34.6 23.2 21.5 4.4 53.5 92.2 65.8 77.4 85.5 4.5 36.6 7.7 141.3 78.9 59.5 34.6 0.7 42.8 7.8 53.1 108.9 45.0 0.5 31.8 164.7 65.6 3.3 16.4 0.8 9.9 33.9 8.5 0.3 58.5 59.9 0.7 59.3 54.0 48.7 58.8 12.0 21.1 4.4 0.7 21.8 30.5 50.0 53.7 7.9 14.2 9.9 9.2 13.9 12.9 2.6 10.3 10.5 12.3 0.9 8.0 9.8 8.0 8.6 8.9 24.9 15.7 5.8 15.5 14.3 15.6 28.1 15.6 18.0 24.9 15.8 19.3 17.0 19.1 20.4 38.0 0.0 7.1 0.3 12.9 14.7 33.5 10.0 6.8 0.5 12.3 25.7 2.0 4.3 6.4 5.5 0.0 10.7 101.2 0.4 0.0 28.1 2.8 4.9 56.0 50.4 12.5 12.8 0.6 6.4 222.1 62.6 2.6 6.2 91.3 140.8 44.3 1.3 119.8 0.0 0.3 0.7 8.2 74.7 77.9 9.4 39.4 78.0 28.4 10.3 61.5 10.0 82.4 8.0 0.2 41.0 0.1 24.5 5.7 40.8 0.1 4.4 3.1 0.8 6.6 26.3 36.1 4.9 8.1 1.1 8.7 9.4 68.9 10.5 0.2 21.6 CMTM4 CKLFSF4 ENSG00000183723 "CKLF like MARVEL transmembrane domain containing 4" Q8IZR5 16 66614750-66696743 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Granulosa cells: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014704, HPA023890" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Vesicles, Plasma membrane" "HPA014704: AB_1847005, HPA023890: AB_1847007" "unprognostic (2.65e-3)" "unprognostic (1.16e-1)" "unprognostic (6.17e-3)" "unprognostic (3.43e-1)" "unprognostic (5.13e-1)" "unprognostic (8.30e-2)" "unprognostic (2.88e-2)" "unprognostic (2.65e-1)" "unprognostic (3.35e-3)" "unprognostic (6.06e-3)" "unprognostic (2.07e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.72e-9)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" 4.5 5.0 36.4 2.7 34.1 2.5 5.7 32.8 34.5 3.9 28.3 16.1 11.9 4.4 20.1 6.0 10.6 2.9 4.1 43.1 37.1 26.3 4.1 8.4 0.6 42.1 41.7 3.4 19.2 32.7 14.4 2.1 35.4 7.7 12.6 7.8 11.1 3.8 3.3 7.7 12.9 3.4 41.8 2.0 31.4 6.9 45.5 0.5 38.6 2.1 1.1 3.2 4.1 41.6 16.0 12.9 7.8 19.1 2.6 4.2 31.7 6.6 5.9 3.5 5.6 24.2 17.7 0.7 10.8 3.9 4.8 20.0 19.7 7.8 5.2 1.3 17.2 1.7 5.3 15.2 5.6 1.4 3.0 6.7 13.4 4.2 8.1 11.9 2.0 2.3 8.0 4.1 5.1 18.5 0.1 3.2 8.7 28.6 8.6 3.5 10.6 4.9 15.2 14.2 17.9 7.1 27.4 14.6 9.3 5.6 15.3 3.4 4.3 6.5 7.0 1.8 6.6 1.4 3.3 0.7 8.1 3.2 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 36.4 34.1 32.8 34.5 43.1 37.1 42.1 41.7 35.4 41.8 45.5 41.6 2.6 22.4 11.1 32.7 0.8 5.2 8.8 21.9 4.6 9.5 23.5 10.8 7.1 15.7 19.3 23.9 8.4 5.0 1.6 51.7 13.7 15.9 1.9 20.7 2.7 4.3 39.0 0.8 68.0 24.0 29.6 3.5 27.5 12.3 4.5 67.6 1.8 6.1 2.4 30.3 37.7 24.1 20.3 2.8 0.9 3.0 2.5 1.9 3.6 7.5 4.4 24.2 0.0 37.7 51.3 30.8 19.5 3.0 0.6 29.0 30.7 19.9 40.0 11.1 6.6 3.1 8.8 6.4 7.7 7.5 5.5 2.9 0.9 2.5 43.4 19.4 CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 334.7;Proximal enterocytes: 629.1;Proximal tubular cells: 487.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 458.7;RPMI-8226: 616.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 2600000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favorable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" 54.8 40.7 125.3 75.0 147.0 25.1 60.4 139.4 156.9 136.8 113.0 83.6 190.1 44.2 122.8 78.4 140.8 94.4 63.7 123.7 133.2 327.3 261.1 82.3 86.3 143.1 137.4 34.4 100.7 58.5 48.0 75.4 144.7 122.5 79.5 42.1 57.4 101.7 26.6 47.0 255.0 37.9 140.4 137.0 103.5 20.9 143.9 52.5 159.1 22.4 82.2 94.5 47.4 157.6 64.6 85.0 60.5 57.4 72.2 42.5 252.3 66.0 61.7 88.3 87.4 49.6 67.1 80.3 81.4 72.1 69.0 95.0 92.7 124.9 62.7 121.3 36.7 80.2 42.1 79.6 104.6 158.7 119.3 64.5 93.9 76.4 136.6 50.1 78.3 94.6 86.3 458.7 59.1 71.6 84.9 75.6 91.0 42.4 50.3 91.3 69.4 616.6 346.1 264.1 65.3 34.2 51.6 360.2 91.6 143.0 151.5 64.0 82.5 93.9 79.5 21.2 45.2 85.5 380.6 108.1 63.6 113.8 80.2 37.1 115.4 49.0 77.6 166.3 84.4 102.4 61.6 72.2 185.1 110.5 65.5 72.4 15.9 124.6 174.1 161.3 94.5 135.7 125.3 147.0 139.4 156.9 123.7 133.2 143.1 137.4 144.7 140.4 143.9 157.6 39.2 73.7 62.7 16.6 55.7 9.2 40.3 48.6 12.5 33.6 76.5 36.4 26.9 77.2 56.8 119.5 16.7 157.9 47.8 99.0 187.9 168.1 3.3 187.7 49.7 49.6 65.3 23.3 8.8 154.7 130.9 23.5 63.7 334.7 12.0 34.0 40.0 119.8 216.3 43.7 10.8 82.9 75.3 122.9 24.9 4.1 18.6 79.0 17.8 13.1 90.8 86.6 55.6 15.6 51.7 108.9 103.5 16.6 44.4 65.2 629.1 487.6 73.3 31.6 13.1 15.2 22.3 8.3 7.2 27.1 9.7 109.0 38.2 32.8 99.8 53.8 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 CNTD1 "CNTD, FLJ40137" ENSG00000176563 "Cyclin N-terminal domain containing 1" Q8N815 17 42798800-42811587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 42.4" "Group enriched" "Detected in many" 5 "Early spermatids: 70.5;Late spermatids: 124.8;Respiratory ciliated cells: 47.0;Spermatocytes: 150.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.9;ASC diff: 1.6;SiHa: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA072363 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Vesicles "HPA072363: " "unprognostic (5.92e-2)" "unprognostic (1.99e-3)" "unprognostic (3.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.25e-1)" "unprognostic (6.29e-3)" "unprognostic (6.61e-2)" "unprognostic (1.09e-2)" "unprognostic (7.82e-2)" "unprognostic (6.18e-2)" "unprognostic (1.36e-2)" "unprognostic (2.07e-1)" "unprognostic (5.89e-7)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.81e-4)" 0.3 0.2 0.9 0.0 0.9 0.1 1.8 1.2 1.9 0.1 0.1 0.8 0.1 0.1 1.4 0.0 0.7 0.0 0.1 0.9 1.0 1.5 0.0 0.5 0.0 1.0 0.9 0.4 1.0 0.3 0.0 0.1 0.9 1.3 1.9 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.1 3.3 42.4 0.8 0.0 0.3 0.6 0.0 0.2 0.0 1.9 2.9 0.3 0.2 0.5 1.6 0.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.3 0.0 0.8 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.2 1.9 0.9 1.0 1.0 0.9 0.9 0.8 0.8 1.9 1.2 3.2 4.6 2.3 1.0 0.4 0.5 0.4 0.0 1.7 5.5 2.2 1.1 1.5 2.1 0.0 0.0 0.3 1.2 1.4 5.9 0.2 70.5 5.4 1.7 0.8 0.0 2.7 1.9 0.4 0.4 1.9 4.1 1.6 6.3 0.2 0.4 1.1 0.3 6.7 1.6 5.3 4.1 1.0 0.7 124.8 2.5 1.1 0.0 0.0 0.2 1.0 0.0 2.0 1.1 0.4 0.4 1.2 0.7 5.6 0.9 0.5 47.0 0.7 6.6 1.0 1.7 150.2 17.1 0.0 0.6 0.3 0.9 0.5 2.7 2.3 CNTFR ENSG00000122756 "Ciliary neurotrophic factor receptor" P26992 9 34551432-34590140 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.1;skeletal muscle: 129.7" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Fibroblasts: 22.4;Muller glia cells: 83.6;Paneth cells: 30.6" "Cancer enhanced" "Detected in many" "glioma: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 109.3;SH-SY5Y: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025310 Approved NA NA 55000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "CAB025310: " "unprognostic (1.39e-1)" "unprognostic (9.40e-2)" "unprognostic (1.93e-2)" "unprognostic (1.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (9.70e-2)" "unprognostic (4.45e-3)" "unprognostic (1.72e-2)" "unprognostic (6.32e-2)" "unprognostic (4.99e-3)" "unprognostic (7.37e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" 60.0 10.3 67.2 1.3 91.9 0.0 49.7 81.5 69.0 29.7 16.3 7.6 3.3 2.8 2.6 3.9 13.0 6.3 39.0 54.3 58.5 2.9 12.4 3.8 1.0 57.0 82.8 5.2 2.2 0.2 9.7 5.2 62.2 11.0 2.2 13.9 11.3 7.7 129.7 11.5 8.7 0.7 49.8 30.6 7.0 7.2 94.1 5.1 13.7 35.1 0.4 5.6 17.1 47.4 0.0 0.0 109.3 0.0 13.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 3.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 52.1 0.1 0.1 0.0 1.0 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.2 91.9 81.5 69.0 54.3 58.5 57.0 82.8 62.2 49.8 94.1 47.4 0.9 0.0 0.0 57.1 0.0 3.6 1.1 0.0 1.2 19.3 11.9 1.5 1.3 8.6 0.0 0.0 6.2 0.9 0.1 6.5 1.9 0.1 4.3 0.1 2.4 0.3 0.0 0.0 4.1 0.0 0.6 22.4 0.0 0.1 0.0 0.0 2.5 1.4 1.4 3.3 9.3 0.5 0.0 0.0 2.7 1.9 9.9 0.1 3.6 2.8 0.0 83.6 0.0 15.1 0.5 0.0 30.6 2.2 0.3 0.2 14.1 0.1 0.0 3.2 0.0 1.2 1.9 5.5 19.8 0.3 2.4 2.3 0.2 0.0 0.5 0.3 COA8 "APOP-1, APOPT1, C14orf153, MGC2562" ENSG00000256053 "Cytochrome c oxidase assembly factor 8" Q96IL0 14 103562960-103607523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.2" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 62.6;Cytotrophoblasts: 75.7;Extravillous trophoblasts: 54.9;Hofbauer cells: 85.8;Syncytiotrophoblasts: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.28e-1)" "unprognostic (1.76e-1)" "unprognostic (1.46e-1)" "unprognostic (4.06e-1)" "unprognostic (1.93e-1)" "unprognostic (6.74e-3)" "prognostic unfavorable (6.34e-5)" "unprognostic (1.83e-1)" "unprognostic (7.59e-2)" "prognostic favorable (4.78e-4)" "unprognostic (2.24e-1)" "unprognostic (2.26e-1)" "unprognostic (1.43e-2)" "unprognostic (5.55e-2)" "unprognostic (2.98e-2)" "unprognostic (3.14e-1)" "unprognostic (3.99e-1)" 21.1 13.4 21.9 12.5 21.9 12.1 19.8 23.0 25.5 17.6 22.3 26.9 19.3 15.8 18.5 20.3 13.8 15.4 32.0 22.6 21.8 22.8 18.5 14.6 17.0 22.9 22.0 14.8 24.2 14.8 11.3 16.3 22.7 15.4 19.1 9.5 24.8 15.4 122.2 21.2 16.4 16.4 21.4 12.0 20.1 56.2 21.6 11.3 25.7 77.0 16.9 20.5 15.2 24.6 27.5 19.2 17.1 36.5 39.6 45.2 32.2 29.3 31.7 34.7 41.5 23.3 43.9 24.2 29.6 38.7 33.0 37.9 14.6 33.2 46.4 36.8 19.5 9.9 19.3 18.5 47.8 22.0 21.6 33.9 56.4 22.9 53.6 39.3 38.3 26.8 22.2 34.8 37.9 37.8 21.2 28.8 24.9 66.4 71.9 18.3 19.0 22.8 49.1 26.5 34.1 18.1 21.3 26.8 60.0 23.9 41.1 25.6 28.2 30.6 19.9 46.0 40.7 15.3 31.7 30.3 41.9 22.2 33.0 45.6 25.9 34.3 23.4 24.9 21.8 29.5 22.5 24.0 20.8 30.2 20.8 23.2 15.2 31.4 23.3 20.0 30.4 23.7 21.9 21.9 23.0 25.5 22.6 21.8 22.9 22.0 22.7 21.4 21.6 24.6 15.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.6 0.0 0.0 0.0 0.0 75.7 8.4 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 54.9 11.0 0.0 0.0 0.0 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 69.4 1.4 0.0 0.0 0.0 COASY "DPCK, NBP, PPAT" ENSG00000068120 "Coenzyme A synthase" Q13057 17 42561467-42566277 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022875, HPA022912, HPA023273" Approved "Intracellular and membrane" NA NA 20000 "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "HPA022875: AB_1847066, HPA022912: AB_1847067, HPA023273: AB_1847068" "unprognostic (2.83e-1)" "unprognostic (8.35e-2)" "unprognostic (1.81e-1)" "prognostic favorable (2.15e-4)" "unprognostic (1.01e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.54e-5)" "unprognostic (4.06e-2)" "unprognostic (3.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (5.55e-1)" "unprognostic (1.62e-1)" "unprognostic (2.16e-1)" 27.4 60.0 24.0 23.1 24.0 29.5 32.8 24.7 28.1 27.6 26.7 35.6 43.3 25.2 17.2 54.4 29.8 16.9 29.4 25.4 23.9 45.6 70.9 30.3 25.0 27.8 24.7 26.0 59.0 39.0 30.3 25.5 28.1 32.4 24.3 13.3 58.5 28.7 38.6 46.6 36.9 17.2 23.8 35.9 47.2 32.4 25.7 27.6 39.0 25.3 25.2 26.8 31.1 24.6 94.2 149.1 27.2 55.2 55.5 34.8 89.2 38.3 52.9 65.8 46.5 85.7 89.2 52.7 65.6 50.4 69.5 146.9 66.1 81.4 43.7 47.6 122.2 52.5 91.2 140.9 70.2 56.4 73.1 51.5 97.8 62.4 66.6 52.4 63.2 70.5 98.7 70.8 46.6 59.2 71.5 87.2 36.7 125.8 75.1 39.1 93.5 88.1 89.9 66.7 63.3 50.1 34.9 37.3 75.4 52.2 158.0 70.4 41.6 68.3 62.3 52.4 40.1 84.6 127.4 31.0 80.9 55.3 47.5 23.3 29.8 26.8 19.7 31.8 20.5 15.8 15.8 19.1 33.6 15.7 15.7 16.3 19.5 21.0 22.5 23.6 18.1 24.0 24.0 24.0 24.7 28.1 25.4 23.9 27.8 24.7 28.1 23.8 25.7 24.6 15.4 6.4 23.8 9.8 24.1 15.0 21.7 49.5 25.6 17.8 38.2 22.9 22.9 40.0 33.3 71.7 0.0 89.4 21.2 53.7 33.2 44.8 4.4 31.5 20.6 20.6 17.4 30.3 5.6 52.5 51.6 18.7 40.2 28.0 10.2 101.2 23.9 94.2 40.3 33.7 5.7 36.7 42.7 23.6 16.1 7.7 14.9 19.9 14.2 4.7 36.2 29.4 20.6 3.5 5.9 38.9 32.4 16.6 25.3 31.2 66.3 94.8 36.5 18.0 26.3 15.2 18.6 46.7 31.1 33.4 17.8 77.2 16.9 36.6 45.1 30.7 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL25A1 ENSG00000188517 "Collagen type XXV alpha 1 chain" Q9BXS0 4 108808725-109302752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0;retina: 24.7;testis: 19.1" "Cell type enhanced" "Detected in some" "Early spermatids: 107.1;Inhibitory neurons: 275.3;Late spermatids: 39.2;Rod photoreceptor cells: 71.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HeLa: 47.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029107 Approved "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Endoplasmic reticulum" "HPA029107: AB_10600802" "unprognostic (1.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "unprognostic (8.87e-5)" "unprognostic (2.43e-2)" "unprognostic (3.20e-1)" "unprognostic (7.62e-3)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (3.53e-1)" "unprognostic (1.50e-2)" "unprognostic (1.17e-1)" "unprognostic (5.30e-3)" "unprognostic (2.82e-3)" "unprognostic (9.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" 6.1 0.5 13.4 0.1 10.3 0.0 2.8 0.0 30.0 1.1 0.3 0.4 2.9 0.6 1.6 0.4 0.9 2.2 0.5 17.8 13.7 1.9 2.2 0.2 0.1 6.5 9.4 1.0 0.2 1.3 7.0 0.3 1.0 0.5 0.3 24.7 4.9 0.5 1.0 0.7 2.5 0.8 6.9 0.8 0.3 19.1 8.9 0.5 2.8 0.3 0.1 0.7 1.0 1.7 0.0 0.0 5.3 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 2.7 0.0 0.1 0.0 3.2 5.9 47.6 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.2 0.0 0.1 1.2 0.2 5.6 0.0 0.8 0.0 1.6 0.0 0.1 0.0 2.6 0.0 0.0 0.0 1.1 0.0 0.0 0.2 1.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 10.3 0.0 30.0 17.8 13.7 6.5 9.4 1.0 6.9 8.9 1.7 8.2 0.0 0.0 12.4 0.1 0.0 0.1 0.0 2.2 2.1 0.4 0.6 1.0 0.0 0.6 1.8 4.2 0.0 0.0 0.0 0.0 0.0 107.1 6.5 2.0 1.6 0.0 0.0 20.5 0.0 0.0 0.7 0.0 18.9 0.0 0.5 0.7 0.0 0.0 1.7 275.3 0.0 0.0 0.0 0.4 39.2 0.6 0.2 0.0 10.3 0.0 2.8 0.0 16.6 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 71.5 0.0 4.7 24.6 7.8 1.6 0.0 0.1 0.0 0.1 0.3 0.0 0.0 COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 401.4;Endometrial stromal cells: 312.2;Endothelial cells: 385.9;Extravillous trophoblasts: 672.4;Sertoli cells: 506.2;Smooth muscle cells: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "ASC diff: 501.6;EFO-21: 915.3;TIME: 331.3" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" 348.4 33.6 10.8 135.9 5.2 0.4 130.4 3.7 9.0 65.7 8.9 108.5 24.8 105.3 14.8 40.8 64.1 116.8 81.9 12.6 5.2 53.4 22.1 137.0 27.7 9.1 7.0 27.0 36.0 36.3 12.8 900.3 7.5 53.6 30.4 1.8 19.0 85.6 40.1 25.2 43.4 312.7 6.8 76.3 50.1 10.7 13.7 10.7 54.7 47.0 11.1 120.8 38.2 6.9 40.0 15.2 195.9 0.3 501.6 148.9 274.9 246.2 59.5 134.0 65.3 4.2 0.8 0.1 915.3 46.2 59.7 26.8 0.0 55.8 30.3 1.3 29.5 0.2 28.2 0.0 142.8 0.0 0.4 49.7 8.9 132.8 59.4 212.8 207.7 0.1 0.3 0.2 31.1 0.1 0.1 0.8 28.1 0.2 3.6 0.4 58.6 0.1 278.8 0.0 1.4 29.8 0.1 0.4 61.0 192.4 0.1 13.9 331.3 39.9 121.4 1.0 97.4 0.3 1.8 3.9 0.4 0.7 297.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 10.8 5.2 3.7 9.0 12.6 5.2 9.1 7.0 7.5 6.8 13.7 6.9 401.4 41.7 8.9 5.2 1.9 14.0 9.7 8.5 2.8 1.0 3.5 16.5 41.1 10.0 0.9 23.9 0.0 49.7 0.5 0.1 1.9 22.6 0.7 19.8 312.2 385.9 0.0 0.0 10.5 0.2 672.4 211.8 1.5 48.7 1.3 215.8 134.6 1.3 27.7 0.0 18.9 0.5 0.0 4.4 19.2 2.8 38.5 4.2 30.2 36.5 0.6 2.5 0.0 1.0 0.9 0.6 0.1 109.4 0.5 6.2 0.5 26.7 2.8 0.4 506.2 142.8 415.1 1.2 5.0 0.8 15.2 45.0 4.2 45.9 0.6 2.2 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Astrocytes: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 38.9;BJ: 23.6;BJ hTERT+: 26.2;BJ hTERT+ SV40 Large T+: 14.4;HSkMC: 28.2;WM-115: 26.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" 47.4 5.0 33.2 9.9 33.2 0.1 32.3 30.6 45.9 44.9 43.6 19.3 3.7 27.3 1.9 9.0 22.8 4.1 33.5 33.3 26.4 7.9 13.4 14.2 3.2 35.2 30.2 6.3 5.2 3.0 3.5 32.8 32.3 16.6 2.0 21.1 7.3 8.9 15.3 21.7 11.7 10.3 31.0 1.7 9.9 4.7 30.2 4.5 12.7 6.0 3.9 12.6 26.4 28.4 0.0 0.0 0.5 0.0 12.4 38.9 0.0 23.6 26.2 14.4 5.7 0.0 0.0 0.0 0.2 4.4 0.3 2.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 28.2 0.6 5.2 5.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.1 0.0 0.0 0.0 11.6 5.5 0.5 0.0 0.0 0.0 0.0 1.5 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 33.2 30.6 45.9 33.3 26.4 35.2 30.2 32.3 31.0 30.2 28.4 13.7 0.0 0.0 510.3 0.0 4.2 0.1 0.2 2.2 65.1 0.3 0.9 6.4 0.0 0.1 0.0 6.2 0.1 0.3 1.3 0.0 0.2 6.9 0.4 12.0 8.1 0.0 0.0 15.6 0.0 0.2 17.5 0.5 0.4 0.0 0.0 3.9 22.9 0.6 3.3 3.4 0.0 0.0 0.0 3.2 2.1 17.4 0.4 14.2 36.5 0.1 2.6 0.0 73.9 2.5 0.3 0.1 8.2 0.0 0.3 0.2 0.1 0.9 28.3 92.1 8.5 58.0 0.3 0.3 3.2 7.1 0.1 1.9 0.9 0.0 0.3 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.2;Cardiomyocytes: 13.5;Fibroblasts: 13.4;Macrophages: 6.8;Melanocytes: 7.2;Microglial cells: 8.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.8;fHDF/TERT166: 4.3;HHSteC: 14.1;hTERT-RPE1: 18.2;THP-1: 4.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.6" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" 5.2 1.2 2.5 4.4 2.2 0.5 5.6 6.1 2.4 9.0 18.3 5.9 1.4 5.7 1.6 5.8 4.2 4.8 5.4 2.3 2.9 1.1 0.6 4.6 3.1 9.0 4.2 3.3 0.8 0.7 4.0 12.8 7.1 6.1 2.0 0.4 7.4 11.4 0.6 5.5 2.4 3.7 6.1 8.5 9.1 0.9 4.2 4.9 7.5 2.1 3.5 13.3 5.9 5.7 0.0 0.0 0.0 0.0 0.5 1.0 0.1 5.8 1.7 1.6 0.9 0.2 0.1 0.0 0.8 4.3 0.0 0.3 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 14.1 0.0 0.0 1.7 0.1 0.7 0.0 18.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.1 0.1 0.0 0.5 0.5 0.5 0.0 0.2 0.4 0.0 4.7 0.1 2.3 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.5 2.2 6.1 2.4 2.3 2.9 9.0 4.2 7.1 6.1 4.2 5.7 0.6 0.0 1.8 0.3 0.0 2.2 2.2 1.8 0.0 0.1 1.3 10.2 13.5 0.0 0.7 0.0 0.0 0.4 1.4 0.0 0.0 0.4 0.1 0.2 0.2 0.7 0.0 0.0 0.2 0.2 0.3 13.4 0.5 0.3 2.5 0.5 1.1 0.0 6.2 0.0 0.4 0.0 0.0 2.0 2.7 0.2 3.1 6.8 7.2 8.4 1.2 0.3 0.0 0.5 0.1 0.6 0.0 6.0 0.1 5.3 0.0 0.0 0.2 0.2 6.6 0.7 1.4 0.0 0.3 0.1 1.3 0.8 1.2 0.3 0.0 0.4 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 COPZ2 MGC23008 ENSG00000005243 "COPI coat complex subunit zeta 2" Q9P299 17 48026167-48038030 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 49.8;Endometrial stromal cells: 63.8;Fibroblasts: 77.7;Leydig cells: 50.4;Smooth muscle cells: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 167.4;ASC TERT1: 185.6;BJ: 127.1;BJ hTERT+: 133.1;fHDF/TERT166: 271.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055999 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA055999: AB_2683003" "unprognostic (2.66e-1)" "unprognostic (9.32e-2)" "unprognostic (2.18e-2)" "unprognostic (1.46e-1)" "unprognostic (6.28e-2)" "unprognostic (1.12e-1)" "unprognostic (2.77e-2)" "unprognostic (1.59e-1)" "unprognostic (9.34e-2)" "unprognostic (2.49e-1)" "unprognostic (7.02e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.45e-9)" "unprognostic (7.42e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (2.89e-6)" "prognostic unfavorable (4.66e-4)" 71.7 28.6 11.8 11.7 12.6 1.0 46.4 13.0 19.1 41.8 22.8 57.0 6.2 38.3 21.4 15.9 32.6 22.9 57.1 12.4 16.4 19.2 33.2 22.1 5.8 15.3 12.5 13.6 19.7 24.3 14.8 22.5 15.1 34.2 14.7 5.1 23.4 36.8 90.8 35.3 18.2 45.6 14.0 11.7 27.1 11.6 13.1 4.9 32.1 48.6 6.9 37.3 33.1 15.7 38.7 7.5 4.1 0.0 167.4 185.6 0.0 127.1 133.1 35.0 38.6 0.0 4.4 0.0 28.3 271.6 0.0 39.5 0.0 0.5 34.9 1.7 0.1 13.6 21.3 0.1 68.4 0.0 0.8 111.7 16.0 26.2 3.5 41.1 5.3 0.3 0.1 0.8 86.9 18.1 0.4 0.0 0.2 2.6 2.5 0.0 0.0 6.1 2.4 0.0 0.2 5.7 24.6 0.0 28.3 1.0 6.0 4.2 34.4 91.5 14.5 72.9 0.5 91.6 11.1 1.3 99.3 0.0 13.1 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.1 11.8 12.6 13.0 19.1 12.4 16.4 15.3 12.5 15.1 14.0 13.1 15.7 31.6 9.6 2.2 8.1 2.6 49.8 16.7 9.4 9.1 1.2 7.3 30.1 37.1 0.0 1.4 7.3 0.0 1.0 7.5 0.4 11.7 1.0 7.0 2.1 63.8 15.6 0.0 0.0 1.4 5.1 1.2 77.7 0.0 1.5 1.3 2.7 16.4 39.0 6.9 0.0 1.7 2.3 2.0 4.4 28.4 21.1 50.4 3.4 28.4 7.5 0.8 34.8 4.1 2.5 7.6 2.5 0.0 41.8 3.5 6.0 0.1 19.1 0.6 1.3 6.6 21.6 49.2 14.1 3.7 3.1 26.0 2.3 3.7 8.5 0.4 11.7 COQ8A "ADCK3, CABC1, COQ8, SCAR9" ENSG00000163050 "Coenzyme Q8A" Q8NI60 1 226940286-226987544 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 1165.1;tongue: 484.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.9;Collecting duct cells: 33.1;Ductal cells: 21.2;Exocrine glandular cells: 32.7;Proximal tubular cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 82.0;RPMI-8226: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061662 Supported Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA061662: AB_2684578" "unprognostic (6.37e-3)" "unprognostic (2.09e-2)" "unprognostic (2.29e-1)" "unprognostic (9.06e-2)" "unprognostic (8.94e-2)" "unprognostic (2.49e-1)" "unprognostic (4.42e-2)" "unprognostic (3.50e-3)" "unprognostic (1.81e-1)" "unprognostic (4.02e-1)" "unprognostic (4.15e-3)" "unprognostic (8.67e-2)" "unprognostic (2.40e-2)" "unprognostic (9.24e-2)" "unprognostic (2.82e-1)" "unprognostic (8.88e-2)" "unprognostic (2.62e-1)" 63.9 123.8 7.1 10.3 8.0 26.1 35.8 17.3 8.1 16.5 16.1 30.8 29.9 15.9 0.5 32.2 24.6 19.7 123.5 7.1 5.6 14.4 35.7 9.6 12.7 8.9 5.4 34.1 93.8 6.4 5.3 6.5 9.8 18.5 6.4 1.3 32.7 11.7 1165.1 25.1 18.5 7.2 5.9 14.4 52.8 6.7 5.9 8.6 9.4 484.7 4.3 40.8 13.4 11.5 8.0 14.4 3.3 10.3 11.4 7.3 57.7 3.6 2.9 5.2 6.9 23.0 12.8 24.5 17.9 2.4 2.6 9.2 6.9 8.2 0.8 25.5 82.0 16.7 11.2 38.8 2.5 25.8 9.3 14.2 12.2 4.0 5.4 4.9 2.5 24.7 29.4 19.4 0.7 11.0 15.2 37.3 15.5 62.8 29.5 14.9 17.1 78.6 1.6 5.9 59.9 24.2 7.3 28.7 20.6 3.4 15.1 34.8 2.5 5.9 5.3 8.2 13.3 43.0 40.5 13.1 5.3 29.3 6.0 47.7 23.5 68.4 15.8 17.1 15.3 22.2 15.8 14.6 18.6 26.8 21.5 17.0 43.1 21.2 13.6 8.1 21.5 26.0 7.1 8.0 17.3 8.1 7.1 5.6 8.9 5.4 9.8 5.9 5.9 11.5 11.4 3.2 21.9 0.0 5.8 0.0 0.0 0.0 0.0 0.0 18.1 17.1 0.0 0.0 4.3 33.1 0.0 12.2 10.2 0.0 15.6 21.2 0.0 12.3 8.9 5.4 0.0 0.0 0.0 32.7 10.0 6.3 0.0 9.6 13.9 9.8 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 11.4 0.0 0.0 0.0 0.0 10.8 0.0 0.0 3.2 0.0 0.0 24.8 2.2 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 7.7 5.2 16.0 0.0 0.0 CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Bipolar cells: 43.2;Cone photoreceptor cells: 37.5;Excitatory neurons: 96.6;Inhibitory neurons: 50.0;Oligodendrocytes: 146.4" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 26.8;ASC TERT1: 57.5;HSkMC: 41.6;hTEC/SVTERT24-B: 34.6;U-87 MG: 59.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" 10.9 3.5 44.1 2.0 60.9 0.7 7.2 62.1 66.5 7.2 28.2 5.9 1.2 7.5 2.2 1.4 27.5 4.7 16.4 48.1 43.5 9.2 1.3 5.1 1.8 62.4 62.7 14.9 2.2 0.5 3.5 3.2 58.0 4.3 1.5 45.2 2.7 4.9 2.6 4.1 2.8 6.3 51.9 3.9 3.1 1.0 66.5 1.3 6.1 4.5 0.8 4.1 3.7 83.4 0.6 0.8 26.2 2.2 26.8 57.5 0.0 13.7 15.0 2.3 3.2 0.3 3.0 3.5 1.6 2.3 3.7 0.2 1.0 0.3 9.5 0.0 1.2 0.0 0.0 1.2 9.8 0.0 0.4 41.6 0.3 34.6 2.0 20.4 1.0 0.0 0.0 0.1 24.4 0.1 0.0 0.1 6.5 0.0 0.1 2.2 0.1 1.2 3.7 0.0 15.3 0.3 0.2 0.0 7.8 4.8 0.0 3.1 0.2 7.8 8.9 1.7 18.3 0.0 0.0 3.5 59.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.1 60.9 62.1 66.5 48.1 43.5 62.4 62.7 58.0 51.9 66.5 83.4 2.8 0.0 0.0 57.1 1.1 1.0 0.4 0.0 0.0 43.2 0.1 1.0 1.5 0.0 0.0 7.3 37.5 0.0 0.0 0.0 0.0 3.8 0.4 2.1 11.6 3.0 3.6 0.0 96.6 0.6 0.0 8.0 0.0 0.3 0.0 0.9 6.4 0.0 0.2 0.0 50.0 0.3 0.0 0.3 0.7 0.7 7.8 0.3 7.2 11.2 0.1 12.5 0.0 17.1 146.4 0.6 0.0 0.4 0.0 0.1 0.0 0.1 8.1 21.4 6.6 1.4 2.1 0.2 0.5 0.1 0.9 0.0 0.1 7.5 0.0 0.1 COX14 "C12orf62, MGC14288" ENSG00000178449 "Cytochrome c oxidase assembly factor COX14" Q96I36 12 50112082-50120457 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 835.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044618, HPA062014" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044618: AB_10960419, HPA062014: AB_2684657" "unprognostic (5.71e-2)" "unprognostic (1.86e-2)" "unprognostic (1.43e-1)" "unprognostic (4.04e-1)" "unprognostic (1.87e-2)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (4.20e-3)" "prognostic unfavorable (7.90e-4)" "unprognostic (7.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.09e-3)" "unprognostic (3.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-3)" 124.0 106.4 96.3 47.1 101.4 66.2 105.6 110.3 129.7 63.6 120.1 92.4 83.4 46.2 130.5 68.5 54.9 62.9 238.6 94.5 105.5 143.8 145.4 62.3 74.5 102.6 99.8 52.8 62.0 127.8 88.0 54.7 102.9 67.0 77.5 60.6 84.9 80.7 247.6 49.8 84.0 58.7 102.9 66.9 76.5 32.6 104.0 54.9 87.3 276.7 62.0 74.2 47.3 110.2 78.4 168.3 32.8 79.4 169.4 105.7 60.5 61.1 92.7 98.8 89.5 156.7 109.1 69.9 171.9 78.3 82.6 79.0 57.2 87.5 91.7 78.7 236.6 154.3 140.4 139.2 65.1 112.1 133.7 123.8 129.9 67.1 76.7 100.5 96.2 83.1 70.2 153.4 109.1 193.3 93.7 170.3 51.5 116.4 211.3 77.6 52.4 176.8 155.0 149.1 91.0 51.4 92.4 177.5 195.6 72.6 115.1 103.6 75.2 55.0 58.1 92.3 50.1 106.3 199.0 93.5 77.9 105.0 30.9 258.8 197.8 172.7 146.1 194.5 155.6 213.7 186.9 167.0 190.0 188.0 176.7 173.7 67.0 153.1 178.2 247.2 224.8 214.8 96.3 101.4 110.3 129.7 94.5 105.5 102.6 99.8 102.9 102.9 104.0 110.2 91.5 60.9 120.6 11.1 108.8 124.9 91.2 212.9 87.0 68.2 169.2 192.5 524.4 161.5 138.7 222.5 22.9 191.9 111.1 320.9 565.4 131.4 7.1 117.5 58.7 99.2 156.0 69.2 13.1 170.1 122.6 90.3 81.6 88.1 65.4 64.0 88.9 397.9 219.6 47.1 16.3 214.7 187.2 152.3 110.4 22.9 129.2 117.7 149.4 6.5 181.2 111.0 111.2 7.1 22.3 116.8 262.4 109.4 93.0 129.5 492.6 835.5 157.5 67.4 105.2 51.5 130.8 51.1 56.0 121.6 159.3 127.5 112.2 115.4 227.4 118.6 COX4I2 "COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2" ENSG00000131055 "Cytochrome c oxidase subunit 4I2" Q96KJ9 20 31637912-31645006 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1;placenta: 115.4" "Group enriched" "Detected in some" 5 "Sertoli cells: 414.2;Smooth muscle cells: 191.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "SH-SY5Y: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.64e-1)" "unprognostic (2.09e-2)" "unprognostic (2.76e-3)" "unprognostic (2.18e-2)" "unprognostic (4.51e-2)" "prognostic favorable (6.04e-5)" "unprognostic (5.60e-2)" "unprognostic (1.13e-1)" "unprognostic (2.51e-1)" "unprognostic (7.45e-2)" "unprognostic (1.04e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.11e-1)" "unprognostic (3.30e-3)" "unprognostic (1.43e-1)" "unprognostic (5.59e-2)" 19.1 1.1 6.7 1.7 6.7 0.0 15.9 6.5 9.1 4.8 6.1 4.7 1.9 7.5 3.9 5.4 4.9 10.6 39.7 6.5 6.7 10.9 1.1 49.1 4.7 6.8 7.0 2.9 2.3 9.3 2.2 115.4 7.0 10.1 2.7 1.1 3.6 4.7 8.7 4.9 5.8 7.1 6.6 1.7 4.2 1.5 7.0 1.8 14.7 19.4 3.0 7.7 6.7 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 6.7 6.5 9.1 6.5 6.7 6.8 7.0 7.0 6.6 7.0 6.6 55.0 0.0 0.0 0.0 0.5 6.4 0.3 0.0 2.2 0.4 0.9 1.9 2.7 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.1 0.7 23.5 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 7.5 0.7 3.7 0.5 8.8 2.8 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.7 414.2 4.6 191.6 0.1 1.0 0.8 6.7 2.5 1.0 1.0 0.0 0.3 COX5A ENSG00000178741 "Cytochrome c oxidase subunit 5A" P20674 15 74919791-74938083 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1749.5;skeletal muscle: 1609.7;tongue: 1735.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1645.3;Distal tubular cells: 1475.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027526 Supported NA NA 530000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA027526: AB_10602802" "unprognostic (7.32e-2)" "prognostic favorable (2.15e-4)" "unprognostic (4.06e-2)" "unprognostic (9.85e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (3.79e-2)" "unprognostic (9.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.77e-1)" "unprognostic (8.62e-2)" "prognostic favorable (6.06e-7)" "unprognostic (9.78e-2)" "unprognostic (2.22e-1)" "unprognostic (1.30e-1)" "unprognostic (3.81e-3)" 175.6 176.7 187.1 105.1 189.5 148.5 150.8 231.1 258.1 109.8 201.3 454.2 326.9 98.2 110.7 293.0 89.3 67.8 1749.5 193.1 229.3 373.5 349.6 133.0 125.6 216.1 207.5 71.1 259.3 385.3 141.1 88.0 208.8 118.4 398.2 194.1 211.2 99.2 1609.7 169.0 269.6 95.0 194.8 150.8 306.8 217.8 220.4 150.7 141.5 1735.8 197.9 141.2 146.3 193.8 300.4 309.1 376.8 331.1 227.2 260.2 443.1 262.7 222.3 317.7 294.8 346.0 352.1 700.0 322.0 219.5 387.8 567.7 898.3 368.4 263.7 401.0 906.2 566.6 299.7 436.0 283.9 642.7 335.0 266.6 389.9 198.3 445.1 217.4 377.7 450.0 522.2 429.9 321.2 222.4 558.8 494.6 408.7 575.8 540.1 499.0 369.7 778.4 469.8 472.4 570.5 250.1 396.6 569.2 871.3 407.6 286.3 507.6 274.3 241.4 238.7 303.9 421.1 508.4 1000.3 759.0 258.2 836.1 224.5 332.4 361.5 210.2 198.1 465.6 238.6 296.4 242.4 235.7 452.9 227.3 171.6 198.0 87.4 354.9 432.7 365.2 372.6 426.4 187.1 189.5 231.1 258.1 193.1 229.3 216.1 207.5 208.8 194.8 220.4 193.8 120.7 99.3 119.6 20.5 166.6 158.2 235.3 623.6 151.4 113.4 202.6 313.4 1645.3 221.6 324.0 171.0 39.6 502.8 162.7 987.6 1475.2 407.5 1046.3 199.4 124.3 163.8 461.4 227.3 18.9 436.7 528.2 156.3 247.2 192.8 104.0 143.3 117.8 471.8 571.5 92.5 25.1 890.5 496.4 286.0 209.1 819.6 100.3 238.6 250.8 17.8 413.7 159.9 162.7 15.6 20.2 412.1 817.3 85.7 350.7 319.3 1276.3 921.7 242.7 176.8 92.1 139.6 590.9 523.0 253.6 371.3 159.0 511.0 144.2 216.5 1045.6 393.3 COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 18 "heart muscle: 2260.5;skeletal muscle: 6947.0;tongue: 4960.0" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 21879.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 162.5;ASC TERT1: 122.3;BJ: 84.7;BJ hTERT+: 102.7;fHDF/TERT166: 178.6;HHSteC: 91.4;HSkMC: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "unprognostic (6.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (7.84e-3)" "unprognostic (7.27e-3)" "unprognostic (9.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-2)" 269.2 91.5 197.5 20.4 198.8 2.1 105.9 195.3 256.5 70.6 197.2 122.8 14.9 54.6 39.3 82.3 57.8 31.9 2260.5 210.0 214.7 86.9 11.9 63.3 12.0 197.7 188.7 46.0 40.6 147.8 105.6 27.4 199.5 86.6 23.7 49.7 88.0 119.1 6947.0 33.8 36.7 85.1 192.1 34.4 46.7 9.7 200.0 85.8 54.8 4960.0 7.3 88.5 50.1 217.9 0.5 5.9 0.6 0.1 162.5 122.3 0.0 84.7 102.7 3.4 0.0 0.0 1.8 1.4 13.0 178.6 0.0 0.7 0.0 0.0 0.8 0.2 1.8 0.4 2.1 0.3 91.4 0.0 0.8 109.0 0.0 0.0 0.0 0.0 11.3 0.0 0.6 0.7 0.0 0.8 0.0 0.7 1.0 0.6 1.2 0.2 0.0 0.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.1 20.7 0.0 1.3 0.5 0.4 0.8 1.9 0.7 0.2 0.8 1.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 197.5 198.8 195.3 256.5 210.0 214.7 197.7 188.7 199.5 192.1 200.0 217.9 309.7 0.0 5.1 2.3 2.2 26.4 1.0 28.2 2.8 80.6 25.0 89.4 21879.1 18.6 11.0 22.0 45.9 1.0 1.5 0.0 817.8 13.7 17.0 6.0 124.6 360.4 0.0 5.3 5.9 14.1 0.7 602.1 0.5 3.7 45.0 5.5 259.5 7.3 24.0 67.3 4.3 0.0 26.4 10.7 30.5 90.8 224.6 5.2 284.6 3.7 0.0 31.5 0.0 2.0 2.3 6.2 0.0 281.3 1.5 3.5 0.0 183.1 10.7 84.7 184.1 328.4 463.4 2.0 3.8 4.3 19.0 1.9 4.8 17.3 0.1 0.8 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865296-148897203 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 112.0;lung: 86.3" "Cell type enriched" "Detected in some" 26 "granulocytes: 4422.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 1534 "basophil: 1115.4" "Lineage enriched" "Detected in single" 5518 "granulocytes: 1115.4" "Cell line enriched" "Detected in some" 45 "HEL: 303.3" "Not detected" "Not detected" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 18.2 2.6 0.0 19.9 0.4 25.7 20.9 0.0 0.0 59.4 0.3 39.2 27.3 26.1 19.3 41.1 6.6 112.0 6.2 0.0 0.0 3.3 2.7 86.3 11.2 0.0 0.0 0.9 21.0 2.8 0.9 1.7 0.0 18.5 56.6 0.0 12.1 15.1 1.6 17.7 45.9 25.7 0.0 1.1 45.3 3.8 0.0 14.9 0.9 10.2 15.1 54.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 303.3 0.0 0.0 0.2 0.2 6.7 0.2 0.0 0.1 0.3 0.5 3.8 0.0 0.1 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1115.4 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.1 163.9 0.0 0.5 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 16.0 0.0 1.6 0.0 3.5 0.5 0.0 4422.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 5.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 6.7 0.3 0.0 0.0 8.7 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.3 0.0 41.7 0.0 0.0 0.3 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 727.4;Bipolar cells: 569.1;Cone photoreceptor cells: 621.3;Enteroendocrine cells: 587.4;Leydig cells: 500.8;Muller glia cells: 530.9;Peritubular cells: 621.0;Rod photoreceptor cells: 803.3;Sertoli cells: 854.6;Smooth muscle cells: 519.4" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 311.6;SCLC-21H: 418.2;SiHa: 629.0;SuSa: 342.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" 138.1 151.7 554.8 20.5 593.0 1.8 97.5 550.9 604.0 53.9 311.9 44.6 22.0 67.7 404.6 74.8 88.6 65.7 100.7 584.3 643.3 68.4 26.7 50.1 37.5 417.0 494.2 104.0 170.4 89.9 328.4 7.7 456.2 295.1 36.8 741.7 104.5 84.7 56.2 45.1 30.7 83.3 448.3 11.6 80.2 146.2 578.2 68.8 179.7 47.5 35.2 33.8 73.4 446.2 0.2 8.4 54.4 10.5 41.4 4.5 2.4 0.1 21.5 8.1 16.5 0.0 0.5 0.0 15.8 0.6 1.9 1.2 20.4 4.4 4.7 0.3 78.6 0.0 21.6 311.6 3.0 0.3 0.5 102.3 21.5 0.3 0.4 104.0 0.2 0.0 0.1 2.1 11.2 15.4 0.4 2.7 34.4 0.2 12.1 0.3 0.2 1.1 0.7 3.4 418.2 138.0 629.0 77.9 0.0 342.6 46.7 1.9 0.0 16.7 42.5 1.5 1.5 23.5 0.6 2.2 15.5 0.7 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 554.8 593.0 550.9 604.0 584.3 643.3 417.0 494.2 456.2 448.3 578.2 446.2 87.1 0.0 5.6 727.4 0.6 26.1 81.7 10.3 66.0 569.1 25.6 52.1 54.5 54.3 5.0 22.0 621.3 0.6 1.4 2.9 0.0 19.7 6.7 2.2 12.1 130.4 587.4 2.7 234.8 1.8 0.3 249.0 31.6 1.3 0.0 8.6 274.2 15.1 1.0 70.7 129.0 16.2 38.7 5.4 41.2 23.3 500.8 6.3 87.2 94.6 1.0 530.9 0.0 211.6 23.0 12.4 3.7 621.0 0.7 434.6 10.2 12.7 1.2 803.3 854.6 14.1 519.4 19.7 13.3 14.0 20.9 0.8 5.5 15.4 4.0 18.9 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.0;Inhibitory neurons: 44.3;Oligodendrocytes: 196.5;Spermatocytes: 34.1;Spermatogonia: 62.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 37.9;U-2197: 106.0;U-87 MG: 39.1" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.8 5.0 10.4 1.3 18.6 0.2 2.5 20.3 18.6 9.3 4.5 6.8 1.2 4.2 7.9 3.6 8.3 4.0 2.9 12.7 17.0 1.2 0.2 1.6 0.5 21.3 21.7 14.3 1.3 0.8 21.8 0.3 24.0 2.3 2.4 4.5 1.5 3.7 2.4 1.9 2.5 3.4 15.0 0.6 2.5 32.4 20.4 0.4 2.3 10.5 0.5 7.7 6.1 33.6 0.1 3.6 0.3 0.4 2.6 0.2 0.1 2.8 0.3 1.8 1.4 0.2 0.1 0.0 6.3 1.1 19.5 0.1 5.1 0.0 0.4 0.0 4.2 0.1 0.1 0.1 1.8 0.1 2.3 1.4 0.0 3.5 0.0 0.2 0.0 7.6 8.9 0.2 1.3 0.2 0.6 0.1 8.2 0.1 1.0 0.0 0.2 0.1 0.0 0.1 10.5 2.4 9.2 0.5 37.9 11.2 0.1 1.1 0.1 18.9 7.5 106.0 6.0 5.3 14.3 1.4 39.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.4 18.6 20.3 18.6 12.7 17.0 21.3 21.7 24.0 15.0 20.4 33.6 0.3 0.0 0.0 19.6 0.1 0.8 0.3 0.0 0.0 11.5 0.6 0.3 1.9 0.0 0.0 0.0 10.4 0.0 0.1 0.1 0.0 0.1 12.6 0.5 1.4 0.2 0.0 0.0 70.0 0.0 0.0 5.9 0.5 0.1 1.3 0.3 0.4 0.0 0.3 11.8 44.3 0.0 0.0 0.0 0.8 20.0 4.1 0.4 5.4 10.3 0.1 5.2 0.0 10.1 196.5 0.1 0.0 2.2 0.2 0.5 0.0 0.4 2.2 4.3 6.6 1.9 1.8 34.1 62.3 0.0 0.6 0.1 0.4 0.0 0.0 0.1 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 115.5;Microglial cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 66.8;THP-1: 38.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038600 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" 12.0 8.3 7.0 5.4 7.6 4.6 9.6 3.1 11.5 7.8 9.2 8.1 3.3 5.1 3.5 5.4 5.0 9.0 12.2 10.1 8.9 11.2 15.5 10.1 5.4 5.0 6.5 5.7 3.2 2.5 3.3 12.0 4.6 3.7 10.2 6.0 3.2 8.9 2.9 6.1 4.6 9.1 8.8 10.6 3.7 5.8 8.0 3.1 7.8 5.3 3.2 10.1 5.3 5.5 3.1 18.7 1.3 18.5 17.0 14.3 8.6 1.6 0.1 0.0 0.0 9.4 18.2 0.0 26.3 12.7 6.8 1.0 10.8 5.6 0.0 0.0 11.3 9.9 26.3 2.2 11.3 0.0 7.8 6.7 14.2 4.2 14.9 12.9 14.3 0.0 6.0 0.0 0.0 0.0 0.0 0.1 13.8 11.5 19.0 0.0 0.0 4.3 66.8 0.5 0.0 0.5 26.0 4.7 14.1 18.8 2.3 38.8 13.6 0.0 12.7 21.6 0.1 6.5 19.3 0.2 17.2 17.8 11.0 2.7 12.0 0.0 1.6 9.4 0.3 0.2 2.1 1.8 7.7 0.6 0.9 1.5 0.7 4.5 6.3 2.5 2.1 2.5 7.0 7.6 3.1 11.5 10.1 8.9 5.0 6.5 4.6 8.8 8.0 5.5 68.8 12.8 8.2 66.3 1.6 31.1 5.9 40.8 19.9 2.1 0.6 6.5 20.3 15.7 23.3 12.9 0.0 29.2 6.9 35.8 15.6 7.6 68.9 2.7 9.4 55.9 11.5 7.4 115.5 4.9 27.2 27.1 0.0 3.0 3.8 18.5 36.0 16.5 25.7 0.0 36.3 9.1 6.1 34.1 42.4 14.5 9.6 19.4 46.2 77.8 19.8 36.4 2.1 25.6 2.9 3.6 51.3 8.2 3.3 7.4 0.0 20.9 17.0 2.7 0.0 24.5 16.9 2.7 2.1 6.1 11.2 7.8 4.3 8.6 8.9 3.5 CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.2;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in some" "B-cells: 32.6;Erythroid cells: 20.4;Kupffer cells: 59.1;Macrophages: 24.9;monocytes: 13.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 53.7;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.7" "Group enriched" "Detected in some" 9 "HL-60: 9.9;HMC-1: 21.8;NB-4: 9.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" 13.2 0.8 0.1 27.2 0.5 10.5 0.6 0.1 2.9 1.2 1.3 1.5 1.3 0.5 0.2 0.9 1.4 2.1 0.6 0.2 0.2 2.5 2.6 3.2 20.1 0.7 0.5 0.2 0.3 0.1 0.2 9.1 1.6 0.2 1.5 0.0 0.4 0.4 0.2 0.1 4.4 6.3 0.1 24.4 1.7 0.6 2.1 1.6 0.3 1.0 17.9 6.7 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 9.9 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.7 4.2 17.2 0.0 2.4 0.7 4.5 0.9 0.4 0.3 2.2 0.2 0.1 15.6 0.0 2.3 0.0 0.0 1.3 0.1 0.5 0.1 2.9 0.2 0.2 0.7 0.5 1.6 0.1 2.1 1.8 0.3 0.0 4.2 0.3 32.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.2 0.2 0.0 20.4 0.3 0.0 0.1 0.6 0.0 0.2 1.3 0.3 0.0 0.4 9.7 0.0 0.4 0.0 0.0 59.1 1.4 0.0 0.0 24.9 0.0 1.9 13.3 0.0 0.0 1.5 4.4 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.3 0.5 0.0 0.0 CRABP2 CRABP-II ENSG00000143320 "Cellular retinoic acid binding protein 2" P29373 1 156699606-156705816 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1189.7;vagina: 604.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 485.4;Breast glandular cells: 224.2;Club cells: 266.7;Squamous epithelial cells: 714.0;Urothelial cells: 506.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1592.5;MCF7: 625.9;T-47d: 1201.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 36.0" HPA004135 Supported Supported Nucleoplasm,Cytosol NA NA 76000 "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA004135: AB_1846516" "unprognostic (1.17e-2)" "unprognostic (9.30e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (1.75e-2)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" "unprognostic (6.45e-2)" "unprognostic (7.79e-2)" "unprognostic (7.23e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.19e-13)" "unprognostic (3.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" 22.2 8.0 9.6 4.8 11.5 5.7 104.5 10.5 18.8 273.7 29.4 13.3 0.9 76.3 4.7 1189.7 83.1 18.2 5.5 10.7 12.8 12.0 2.3 6.4 3.9 8.0 8.2 6.2 3.4 55.1 43.5 40.5 7.8 34.8 4.8 4.5 93.5 57.1 5.0 179.0 3.9 57.0 7.4 7.9 5.6 5.3 12.0 15.5 14.5 1.8 76.2 81.2 604.9 10.1 103.4 5.4 115.3 1.6 147.1 218.0 0.4 215.4 1592.5 17.3 21.3 184.9 369.8 1.6 103.1 234.0 2.2 131.2 28.1 0.8 5.1 2.9 8.1 0.1 13.5 1.6 29.0 0.3 2.5 69.3 10.6 25.4 0.5 13.8 0.7 2.0 1.0 2.2 1.9 625.9 1.7 1.9 136.5 12.3 57.3 1.7 0.8 3.4 2.3 4.0 280.7 20.2 3.0 366.2 1.5 214.9 1201.3 0.7 0.2 4.2 63.1 35.5 13.4 9.8 23.8 1.3 28.6 1.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.5 10.5 18.8 10.7 12.8 8.0 8.2 7.8 7.4 12.0 10.1 7.0 0.0 2.6 1.3 1.8 65.0 131.2 485.4 104.2 1.8 224.2 96.8 0.7 1.5 266.7 16.5 2.1 53.9 4.9 0.9 0.0 12.6 2.2 18.0 51.9 10.3 0.0 0.0 3.1 5.2 6.2 168.4 1.1 29.3 0.0 0.5 6.4 0.2 10.0 0.0 1.8 0.9 40.7 0.0 55.4 1.0 19.9 3.9 62.2 0.0 0.0 1.0 0.0 1.5 0.3 18.1 0.2 37.6 0.2 194.9 0.1 0.3 28.2 0.6 0.0 4.3 40.0 2.0 6.1 714.0 190.7 18.1 7.6 4.8 1.7 506.4 CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.5;tongue: 201.3" "Cell type enhanced" "Detected in many" "Early spermatids: 181.2;Late spermatids: 521.8;Proximal enterocytes: 136.4;Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Nucleoplasm,Nuclear membrane" NA NA 8100 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_2732427" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favorable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" 36.1 51.3 26.4 5.4 26.6 9.0 29.2 27.0 33.8 31.7 27.5 36.1 33.0 24.8 4.0 37.3 23.1 6.6 68.2 25.1 27.8 46.9 151.2 15.2 3.2 28.8 28.2 23.0 107.1 26.3 12.3 6.6 30.6 42.2 4.2 1.7 32.8 8.9 227.5 29.6 37.2 6.8 26.7 15.2 34.0 146.4 30.2 3.1 21.5 201.3 1.6 31.3 27.5 24.4 0.1 39.3 10.7 21.3 13.4 25.9 17.0 15.0 16.6 18.9 12.0 7.8 14.0 1.5 9.2 25.9 23.2 6.7 2.2 4.9 7.2 23.6 0.3 7.3 19.1 30.4 34.1 0.0 26.1 26.3 0.0 15.7 0.9 15.8 26.2 7.2 3.6 5.7 20.0 9.1 0.5 15.9 2.8 32.0 18.0 16.8 21.8 12.2 18.0 0.6 4.2 12.1 0.0 7.1 4.8 3.4 49.7 5.5 22.6 23.0 1.6 32.1 15.4 25.5 22.6 0.1 28.8 4.2 16.8 1.6 8.4 3.5 3.2 5.5 6.7 1.5 4.4 4.3 8.6 1.3 2.6 3.1 1.1 4.4 5.6 3.9 4.5 6.1 26.4 26.6 27.0 33.8 25.1 27.8 28.8 28.2 30.6 26.7 30.2 24.4 10.5 6.4 3.7 5.5 4.9 3.2 4.7 10.8 0.6 1.5 9.7 8.1 57.8 21.5 8.2 3.7 2.1 45.9 6.0 64.5 17.6 22.6 181.2 3.5 15.7 12.9 15.5 17.4 5.3 22.4 55.6 19.3 16.8 9.9 7.0 12.9 14.6 65.7 20.7 1.7 6.1 23.6 14.2 13.9 10.5 521.8 22.1 12.4 5.4 6.5 8.3 15.5 6.2 3.5 4.0 11.6 47.6 24.5 9.6 9.3 136.4 52.0 2.8 1.3 6.6 10.5 15.7 123.5 8.6 57.4 4.5 50.3 7.6 20.1 29.3 13.8 CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.9;Pancreatic endocrine cells: 149.9;Paneth cells: 177.3;Suprabasal keratinocytes: 139.5;Urothelial cells: 243.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 20 "B-cells: 3.1;T-cells: 9.2" "Cell line enhanced" "Detected in some" "A-431: 57.9;BEWO: 35.1;CACO-2: 38.1;HaCaT: 36.9;hTCEpi: 27.8;OE19: 33.1;SK-BR-3: 29.5;T-47d: 25.8" "Low region specificity" "Detected in many" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA013835: AB_1847214" "unprognostic (3.25e-1)" "unprognostic (4.41e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.24e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.42e-3)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "prognostic favorable (8.06e-5)" 0.8 0.4 0.3 4.0 0.7 0.3 5.1 1.2 0.5 9.3 6.1 26.9 36.9 2.2 4.6 54.5 8.2 8.2 0.3 0.3 0.2 34.1 32.5 19.0 0.9 0.4 0.2 0.4 44.0 20.7 15.9 3.5 0.5 9.1 10.5 0.4 24.8 8.9 0.1 41.9 30.6 0.5 0.1 0.8 31.1 0.4 0.2 0.8 16.2 0.0 5.4 6.4 17.6 0.5 57.9 7.0 0.0 0.2 0.0 0.1 35.1 0.0 0.0 0.0 0.0 38.1 23.8 0.3 22.1 0.0 0.3 36.9 0.4 12.5 0.0 0.0 0.4 0.1 0.2 21.5 0.0 0.1 0.1 0.0 27.8 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 15.1 0.2 0.4 1.3 33.1 0.0 0.0 0.0 0.7 16.5 24.0 0.0 0.1 0.2 29.5 0.1 1.7 25.8 0.2 0.0 0.1 0.4 0.2 0.1 0.7 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 1.3 3.1 4.6 2.2 0.0 1.0 9.2 3.6 0.3 0.0 0.0 0.0 3.4 1.9 0.3 0.7 1.2 0.5 0.3 0.2 0.4 0.2 0.5 0.1 0.2 0.5 0.2 35.3 38.0 0.0 2.2 72.1 64.6 81.3 21.1 0.0 43.6 19.9 0.3 71.4 64.0 31.3 0.0 28.1 0.9 160.9 46.9 113.0 0.0 43.8 4.0 1.8 16.8 3.2 0.1 101.5 9.8 2.0 34.7 58.3 1.3 0.1 0.4 31.8 2.5 0.0 0.0 60.2 63.1 1.0 6.2 0.0 0.0 1.3 7.2 0.0 2.7 0.9 0.0 0.0 0.1 149.9 177.3 0.0 3.1 94.4 86.8 44.5 36.3 0.5 0.0 0.0 4.2 1.1 0.4 45.0 139.5 56.2 3.2 0.2 52.0 243.6 CREB3L4 "AIbZIP, ATCE1, CREB3, CREB4, hJAL" ENSG00000143578 "CAMP responsive element binding protein 3 like 4" Q8TEY5 1 153967534-153974361 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 106.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 49.9;Breast myoepithelial cells: 40.1;Intestinal goblet cells: 56.9;Prostatic glandular cells: 49.3" "Group enriched" "Detected in all" 5 "breast cancer: 47.8;endometrial cancer: 28.7;prostate cancer: 109.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 81.8;OE19: 82.7;SK-BR-3: 174.6;T-47d: 139.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA038122 Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nuclear membrane" Mitochondria "HPA038122: AB_10669516" "unprognostic (1.35e-1)" "unprognostic (4.71e-2)" "unprognostic (8.13e-3)" "prognostic favorable (7.21e-4)" "unprognostic (2.04e-1)" "unprognostic (1.40e-2)" "unprognostic (5.51e-3)" "unprognostic (5.02e-2)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-1)" "unprognostic (7.12e-3)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (9.34e-3)" 6.3 8.5 3.5 4.5 3.8 7.6 48.2 4.6 4.7 30.5 4.4 11.5 11.4 12.9 13.0 8.2 19.2 6.7 5.0 3.3 3.5 10.5 14.0 5.8 5.9 3.9 4.1 17.4 13.2 6.7 6.1 6.3 3.7 106.2 15.2 4.9 43.9 7.6 5.6 10.2 9.0 5.7 3.9 7.5 29.3 5.3 3.6 12.0 11.3 5.3 7.4 6.8 6.9 4.7 7.5 10.6 9.8 10.9 6.9 10.0 24.7 6.2 7.2 8.3 7.3 5.1 31.0 13.9 31.7 2.6 6.1 12.0 14.5 9.7 4.5 11.4 5.9 10.3 11.7 8.9 5.6 4.9 8.5 10.9 9.2 7.9 17.9 7.5 7.4 16.5 8.1 16.9 3.8 81.8 9.3 3.8 6.7 82.7 12.7 20.9 10.3 26.1 9.0 5.3 18.5 20.1 6.6 174.6 16.8 12.8 139.9 14.9 4.5 2.5 7.3 5.2 4.9 31.4 17.3 10.6 5.3 8.5 8.2 1.5 2.9 2.2 3.4 1.2 4.5 4.5 1.9 2.4 5.0 4.8 1.8 3.5 0.1 9.4 1.7 5.7 1.8 2.5 3.5 3.8 4.6 4.7 3.3 3.5 3.9 4.1 3.7 3.9 3.6 4.7 7.2 6.4 13.1 3.6 6.2 2.9 13.1 10.1 6.8 5.3 49.9 40.1 2.0 7.2 20.3 1.8 2.1 12.9 5.6 3.6 9.8 14.0 0.4 10.6 5.2 6.9 9.0 8.6 0.4 13.3 17.0 4.8 10.7 13.5 5.7 8.7 4.2 14.2 5.4 0.0 0.4 56.9 6.1 7.5 2.0 0.6 7.2 5.1 5.4 0.0 2.8 6.6 8.2 1.5 2.2 7.9 4.3 2.2 5.3 49.3 4.0 4.1 16.6 8.8 19.7 3.1 5.0 7.4 10.6 6.3 3.0 4.2 4.5 7.6 10.9 7.0 CRK ENSG00000167193 "CRK proto-oncogene, adaptor protein" P46108 17 1420689-1463162 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010485, HPA068087" Approved Approved "Plasma membrane" NA NA 400000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010485: AB_2085043, HPA068087: AB_2685950" "unprognostic (6.82e-3)" "unprognostic (1.94e-1)" "unprognostic (8.70e-3)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" "unprognostic (2.48e-1)" "unprognostic (1.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (3.77e-1)" "unprognostic (1.56e-1)" "unprognostic (3.93e-2)" 48.2 23.2 27.9 20.8 28.3 5.7 30.6 28.1 27.8 26.4 25.2 34.1 26.8 28.2 32.1 26.9 21.0 29.7 27.7 28.2 28.5 31.5 50.1 30.2 17.3 29.6 29.7 24.8 27.3 25.3 11.2 42.2 29.4 23.9 34.4 22.6 23.8 27.0 32.0 20.4 24.2 35.6 30.1 20.4 26.1 20.5 31.2 17.6 36.7 37.9 20.1 31.6 21.8 29.3 45.9 69.8 50.8 54.6 83.7 70.2 47.5 77.3 64.8 59.7 55.3 90.7 26.3 22.0 37.6 89.1 41.7 69.1 68.2 55.8 87.2 11.1 46.6 24.5 43.7 50.2 77.9 10.6 20.9 68.3 64.7 61.9 77.1 45.8 74.3 20.2 42.1 20.3 84.4 46.3 11.5 12.1 46.3 50.4 34.6 24.3 25.7 20.1 78.4 48.4 18.8 49.2 73.5 45.2 54.6 47.7 44.5 17.7 79.8 59.7 33.9 63.8 77.3 9.6 15.8 13.5 50.4 20.6 66.6 6.2 3.9 5.3 3.0 4.2 3.0 3.6 3.2 2.7 4.4 5.2 2.4 3.5 13.9 2.7 4.4 3.9 2.6 1.7 27.9 28.3 28.1 27.8 28.2 28.5 29.6 29.7 29.4 30.1 31.2 29.3 89.5 67.3 51.5 12.7 34.6 149.5 68.8 29.6 50.7 43.8 62.7 45.5 35.2 48.6 33.8 33.1 27.1 63.3 22.1 92.6 41.1 62.1 4.3 55.2 64.5 89.7 49.8 39.5 17.5 65.3 61.6 52.7 47.4 94.1 7.6 33.0 92.8 65.6 45.3 53.8 17.6 61.9 22.4 47.1 91.6 8.3 43.8 46.3 53.4 19.7 45.3 43.5 24.7 12.5 13.6 76.7 60.5 44.0 25.7 77.9 58.3 39.7 32.6 38.9 46.0 59.6 72.9 29.0 58.6 62.8 167.8 85.0 29.9 35.4 66.4 92.2 CRLS1 "C20orf155, CLS1, dJ967N21.6, GCD10" ENSG00000088766 "Cardiolipin synthase 1" Q9UJA2 20 6006093-6040053 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 169.5" "Cell type enhanced" "Detected in all" "Early spermatids: 264.2;Hepatocytes: 208.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 237.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.88e-1)" "unprognostic (8.56e-2)" "unprognostic (9.64e-3)" "unprognostic (1.89e-1)" "unprognostic (1.41e-2)" "unprognostic (2.65e-2)" "unprognostic (1.42e-1)" "unprognostic (2.00e-1)" "unprognostic (9.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-2)" "unprognostic (1.83e-2)" "unprognostic (1.85e-1)" "unprognostic (9.54e-2)" "prognostic favorable (8.02e-4)" 50.1 55.1 14.7 16.9 14.9 28.4 33.2 14.4 17.9 24.0 16.7 32.3 59.2 18.9 19.9 18.5 24.1 19.9 82.8 14.5 14.7 57.8 169.5 27.1 16.5 15.5 15.9 21.2 37.4 28.3 15.8 17.9 15.3 32.6 32.9 15.5 27.5 25.8 86.0 15.1 40.9 23.7 15.3 14.5 46.5 27.8 16.9 16.9 27.2 79.5 18.3 25.8 17.7 15.4 71.7 46.5 27.9 40.0 83.1 74.9 34.5 43.6 50.9 38.8 46.8 61.5 44.4 75.8 31.4 52.6 73.3 45.0 54.6 70.9 57.6 21.9 39.9 99.5 17.0 237.4 59.6 99.7 32.4 44.6 59.4 41.5 73.5 36.8 57.3 40.3 76.4 31.6 44.2 25.9 63.6 90.1 55.4 154.8 42.4 42.3 44.6 80.7 61.8 22.1 50.3 43.4 44.8 98.7 78.1 27.5 35.8 59.6 39.2 45.9 33.4 48.7 59.0 33.8 79.1 79.9 17.6 79.5 43.9 0.0 1.2 0.6 1.2 0.9 2.2 2.3 0.7 0.8 1.3 1.1 1.4 0.8 0.0 1.7 0.5 1.6 0.8 0.4 14.7 14.9 14.4 17.9 14.5 14.7 15.5 15.9 15.3 15.3 16.9 15.4 18.8 22.4 47.6 22.2 26.4 33.8 41.4 19.4 31.9 12.9 35.8 27.7 108.0 64.3 16.2 36.8 4.2 45.1 19.5 36.3 64.6 27.9 264.2 29.7 26.2 22.7 28.6 58.0 37.0 28.8 64.1 33.8 52.0 29.7 14.7 31.6 22.5 208.7 34.2 11.8 28.7 50.7 4.1 40.0 24.1 99.5 30.4 31.9 26.6 32.8 28.9 40.5 25.7 39.7 34.3 28.4 49.1 24.5 41.8 117.7 75.7 141.0 15.0 12.9 13.1 29.2 25.6 23.0 18.4 37.7 27.8 36.3 23.3 32.3 82.9 48.6 CRTAM CD355 ENSG00000109943 "Cytotoxic and regulatory T cell molecule" O95727 11 122838500-122872643 "CD markers, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.2" "Group enriched" "Detected in some" 4 "dendritic cells: 63.8;Plasma cells: 16.0;T-cells: 54.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 38.2" "Immune cell enhanced" "Detected in many" "NK-cell: 54.0" "Group enriched" "Detected in many" 4 "NK-cells: 54.0;T-cells: 33.3" "Cell line enriched" "Detected in single" 34 "SCLC-21H: 12.9" "Region enriched" "Detected in some" 44 "cerebellum: 102.6" "Region enriched" "Detected in all" 7 "cerebellum: 25.7" NA NA 6800000 "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.51e-3)" "unprognostic (6.73e-4)" "unprognostic (1.33e-2)" "unprognostic (3.73e-3)" "unprognostic (2.40e-2)" "unprognostic (5.25e-4)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (5.27e-2)" "unprognostic (1.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.32e-1)" "unprognostic (1.83e-4)" "unprognostic (6.01e-2)" "unprognostic (4.26e-2)" "unprognostic (3.87e-2)" "unprognostic (6.59e-2)" 0.3 0.3 0.3 2.3 0.5 1.8 0.5 38.2 1.4 0.3 0.3 0.5 0.6 0.8 0.5 0.3 0.3 1.5 0.2 0.2 0.4 0.1 1.0 1.8 8.8 1.1 1.4 0.3 0.1 0.1 0.1 0.2 4.2 0.3 0.6 0.0 0.7 0.2 0.1 0.3 1.2 0.2 0.5 3.6 0.8 0.2 0.7 4.9 0.2 0.0 3.5 0.8 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 4.6 0.6 13.0 5.6 12.9 0.1 1.5 27.0 3.6 0.2 4.3 33.3 1.2 54.0 10.5 0.2 0.1 6.0 0.3 0.5 38.2 1.4 0.2 0.4 1.1 1.4 4.2 0.5 0.7 1.6 1.1 0.0 1.1 0.3 0.8 1.5 0.4 0.1 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.0 0.1 63.8 0.1 0.0 0.0 1.2 0.4 0.4 0.3 0.0 0.4 0.5 0.0 0.2 1.6 2.0 0.6 1.3 0.0 0.4 0.2 5.9 0.0 0.7 0.0 0.0 8.8 8.1 1.2 0.0 10.3 3.6 0.0 9.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 16.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.3 0.5 0.0 0.9 0.1 54.1 0.0 0.0 0.5 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5623.2;heart muscle: 10683.1;skeletal muscle: 6972.0;tongue: 9406.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 2889.5;Cardiomyocytes: 6878.2;Muller glia cells: 1664.3;Proximal tubular cells: 7285.9" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ASC diff: 2663.1;fHDF/TERT166: 775.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" 1035.0 106.6 2466.0 113.9 3113.8 0.4 592.2 3032.2 5623.2 439.1 2077.7 678.9 24.6 351.4 179.1 312.2 204.0 71.7 10683.1 2424.9 2666.2 2123.2 37.2 253.4 15.0 3215.2 2856.7 136.0 50.6 24.9 209.2 107.8 3147.1 317.9 78.2 478.7 428.7 358.5 6972.0 317.3 158.5 338.1 2877.3 88.5 263.8 23.5 2815.5 20.9 477.7 9406.7 34.4 490.0 477.5 4060.6 0.1 0.5 0.1 45.0 2663.1 90.9 15.0 54.5 2.5 0.8 2.5 1.7 0.2 0.0 41.7 775.8 0.2 2.0 1.8 2.3 1.4 0.3 0.0 0.0 11.9 3.9 16.9 0.4 0.7 77.1 11.1 0.6 6.2 44.3 0.2 0.0 4.6 2.5 169.5 0.1 0.1 1.1 0.5 0.0 1.0 0.2 0.0 0.6 29.8 0.8 0.1 0.4 5.3 9.1 39.8 63.5 4.9 0.0 1.7 310.1 105.0 6.5 4.1 0.5 0.1 0.6 7.1 0.4 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2466.0 3113.8 3032.2 5623.2 2424.9 2666.2 3215.2 2856.7 3147.1 2877.3 2815.5 4060.6 38.4 83.3 4.1 96.0 51.3 174.9 2889.5 32.1 72.8 16.2 334.4 696.1 6878.2 84.4 15.2 1338.9 18.8 3.9 6.8 0.4 677.0 320.3 24.7 345.4 265.3 88.4 7.1 0.0 6.7 11.5 7.4 880.6 0.0 1008.4 0.0 16.1 35.7 0.7 5.8 10.1 12.6 2.4 8.2 0.3 85.8 12.6 228.6 67.7 483.8 11.2 3.6 1664.3 0.0 7.5 615.7 12.1 0.0 187.7 1.6 855.4 0.0 7285.9 23.2 59.4 138.1 799.9 1053.3 21.6 1.4 56.5 155.1 33.4 55.4 6.7 1.2 249.0 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6" "Cell type enriched" "Detected in some" 21 "Hofbauer cells: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Group enriched" "Detected in some" 5 "Karpas-707: 43.3;RPMI-8226: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 1.3 1.6 1.5 0.9 1.6 0.6 0.6 1.6 2.4 0.6 1.3 0.5 0.4 0.3 9.6 0.4 0.4 1.2 0.4 1.6 1.6 0.2 0.4 0.5 1.2 1.9 1.8 0.2 0.2 0.3 0.5 3.3 2.3 0.2 0.4 0.0 0.4 0.2 0.1 0.1 0.4 0.9 1.9 1.6 0.3 0.3 2.2 0.4 0.2 0.2 0.5 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.3 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 0.0 82.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.2 0.5 0.0 0.0 0.7 0.2 1.8 0.0 2.2 0.0 0.0 1.0 0.0 0.0 10.3 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.5 7.5 0.0 0.0 0.6 1.5 1.6 1.6 2.4 1.6 1.6 1.9 1.8 2.3 1.9 2.2 2.1 0.1 0.0 0.0 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.1 1.3 0.0 0.0 0.2 82.6 0.0 0.2 0.0 0.0 3.5 0.8 0.6 0.0 2.8 1.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.2 0.0 0.0 CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 550.1;tongue: 600.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 670000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB075750: AB_2665756, CAB075751: AB_2665757, CAB075752: AB_2665758, CAB075753: AB_2665759, CAB075754: AB_2665760, HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" 154.2 93.6 29.2 61.7 30.0 111.0 66.3 33.7 49.9 55.4 40.5 110.1 97.7 56.4 32.2 95.6 58.3 42.4 319.3 30.9 34.6 86.6 39.0 58.0 67.2 39.4 32.0 56.0 61.5 127.6 28.9 45.7 39.4 59.0 124.1 128.9 73.7 60.5 550.1 70.5 81.2 77.5 22.5 49.0 66.5 24.4 41.0 69.4 53.0 600.7 106.1 70.2 58.2 31.6 168.9 176.8 141.6 198.2 188.4 173.8 93.3 136.9 132.0 231.1 160.6 271.2 158.2 322.9 128.2 172.6 99.3 182.1 396.8 200.8 234.9 109.3 200.2 222.9 136.1 261.4 107.3 288.4 166.6 188.2 201.6 182.4 232.0 202.2 268.6 163.7 233.2 193.7 214.7 160.8 229.8 121.9 117.5 128.0 247.8 222.3 167.1 247.6 166.2 194.6 189.3 125.2 175.2 251.7 157.7 137.5 297.6 174.3 178.3 127.1 165.3 167.4 147.4 124.5 200.4 206.2 120.4 206.4 119.5 59.6 73.3 205.7 47.0 93.0 61.9 60.6 56.5 45.1 119.3 51.8 59.2 47.9 31.3 51.6 94.0 65.6 63.4 71.2 29.2 30.0 33.7 49.9 30.9 34.6 39.4 32.0 39.4 22.5 41.0 31.6 14.5 16.0 39.5 32.3 31.6 39.0 23.5 26.9 46.7 22.8 38.3 29.7 239.9 15.7 21.5 12.9 62.6 18.5 24.1 66.9 35.2 32.5 6.6 25.1 31.5 27.2 16.9 36.0 21.5 45.1 31.3 25.8 42.3 53.5 27.9 21.3 18.9 29.7 34.3 10.1 24.6 43.9 20.3 39.4 35.0 4.8 20.2 34.6 10.6 9.4 44.8 16.7 16.5 18.6 18.8 44.6 35.7 19.9 46.7 33.1 50.4 22.0 14.9 38.3 13.1 27.8 38.2 29.7 25.8 74.8 52.1 16.8 25.8 32.0 71.3 34.5 CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.4" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 57.3;Sertoli cells: 118.3;Smooth muscle cells: 47.1" "Cancer enhanced" "Detected in all" "melanoma: 74.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.7;SK-MEL-30: 146.1;U-138 MG: 92.1;WM-115: 138.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA 48000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoplasm "CAB016189: AB_784821, HPA001933: , HPA002951: AB_1854449, HPA042785: AB_10964270, HPA050008: AB_2680991" "unprognostic (5.21e-2)" "unprognostic (2.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.56e-2)" "unprognostic (3.58e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.63e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (7.60e-6)" "unprognostic (1.23e-2)" "unprognostic (2.04e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (4.93e-5)" 29.6 1.8 9.0 7.3 7.1 0.0 18.5 6.6 9.3 16.0 1.8 55.4 2.8 34.5 1.4 8.3 15.0 5.6 14.6 7.5 8.2 4.9 0.9 19.4 0.4 11.7 7.8 8.9 2.1 1.2 2.2 15.5 9.7 14.4 2.2 0.1 4.7 11.2 39.6 7.8 15.3 22.7 6.7 5.6 19.1 1.3 7.7 0.6 5.6 10.0 0.3 30.3 12.6 9.8 11.9 0.1 1.0 7.1 1.6 9.8 0.1 64.7 28.6 44.4 28.8 0.1 45.0 0.0 1.5 45.4 6.2 0.6 0.1 0.3 13.6 0.6 0.2 0.0 19.2 0.0 10.0 0.0 0.1 4.8 0.1 13.5 1.5 16.5 0.0 0.0 0.1 0.1 7.6 0.1 0.0 0.2 1.2 0.0 0.3 0.1 4.0 0.1 0.0 0.0 0.1 0.2 1.7 0.1 146.1 1.2 0.9 1.2 0.1 92.1 17.9 3.6 0.8 0.0 0.2 0.0 20.3 0.5 138.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 7.1 6.6 9.3 7.5 8.2 11.7 7.8 9.7 6.7 7.7 9.8 4.9 0.0 0.0 1.0 0.0 2.8 0.7 4.7 0.0 1.4 0.1 0.8 11.4 0.0 0.8 1.8 0.0 0.2 0.5 0.1 0.0 0.0 0.6 0.7 0.7 2.7 0.0 0.0 0.4 0.0 0.6 5.9 1.5 0.4 0.0 1.8 1.1 0.2 1.1 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.3 0.3 12.4 3.7 0.0 0.0 0.0 57.3 0.1 0.0 0.0 0.4 0.0 4.3 0.0 0.1 1.0 0.2 118.3 3.1 47.1 0.0 1.3 0.1 1.8 0.3 0.3 0.1 0.0 0.4 CSRP1 "CSRP, CYRP, D1S181E" ENSG00000159176 "Cysteine and glycine rich protein 1" P21291 1 201483530-201509456 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 2743.3;seminal vesicle: 2571.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 341.2;Breast myoepithelial cells: 737.5;Extravillous trophoblasts: 388.5;Smooth muscle cells: 419.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 11000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA045617: AB_2679391" "unprognostic (7.08e-2)" "unprognostic (1.59e-2)" "unprognostic (4.86e-2)" "unprognostic (9.89e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.61e-4)" "unprognostic (2.87e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.24e-2)" "unprognostic (2.58e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.96e-3)" 344.5 127.2 713.6 224.5 871.4 41.0 321.8 742.5 717.3 542.4 467.6 2743.3 180.6 1904.4 308.4 884.1 1025.6 152.7 194.2 647.3 735.1 192.5 114.7 386.0 64.9 840.1 837.4 319.0 114.6 188.0 117.0 118.3 719.0 947.2 432.0 24.2 250.1 2571.3 64.0 219.8 503.6 2009.6 713.5 165.6 748.3 44.2 848.5 48.0 186.4 53.8 65.7 1494.5 469.1 766.6 83.0 195.3 52.0 116.4 83.2 107.7 273.6 605.7 514.3 455.3 360.9 211.1 57.7 78.7 36.1 325.0 96.7 144.7 32.7 120.3 321.2 169.5 29.3 90.7 220.1 30.7 387.4 72.1 10.2 99.3 105.3 373.0 163.1 253.1 508.1 34.9 4.5 71.9 302.1 232.9 46.6 11.8 0.8 99.0 73.2 18.3 304.9 266.8 212.6 129.7 27.1 22.5 238.0 503.8 163.9 25.6 87.0 74.3 610.6 303.7 195.7 206.6 250.6 40.5 82.6 30.6 303.5 137.6 202.6 75.5 49.8 65.6 37.4 49.3 36.9 25.0 35.8 34.9 65.0 18.1 20.5 25.2 5.0 34.3 54.2 5.2 54.1 46.5 713.6 871.4 742.5 717.3 647.3 735.1 840.1 837.4 719.0 713.5 848.5 766.6 151.8 38.5 47.8 86.5 21.8 49.2 341.2 24.6 207.7 3.4 123.7 737.5 24.8 21.5 36.9 47.8 0.0 88.8 23.3 96.6 49.0 165.1 21.5 30.1 73.6 86.9 57.9 19.1 2.4 171.7 388.5 86.7 36.7 38.9 27.9 13.9 91.1 28.3 66.0 0.0 2.1 80.0 14.2 29.1 55.8 44.9 41.0 37.0 126.3 10.3 73.5 137.4 15.5 6.6 114.8 140.5 71.4 292.3 61.5 113.8 97.2 28.4 25.2 3.1 144.7 37.7 419.9 2.4 3.2 75.3 34.9 160.9 31.2 30.4 69.7 103.6 CST7 ENSG00000077984 "Cystatin F" O76096 20 24949269-24959928 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 1095.6" "Group enriched" "Detected in many" 9 "dendritic cells: 1094.4;Langerhans cells: 541.7;monocytes: 659.7;NK-cells: 1385.2;T-cells: 544.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 1287.0" "Group enriched" "Detected in all" 27 "granulocytes: 342.2;NK-cells: 655.3;T-cells: 1287.0" "Cell line enhanced" "Detected in some" "HL-60: 77.8;HMC-1: 204.6;NB-4: 212.1;U-937: 380.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Low region specificity" "Detected in all" HPA040442 Enhanced "Secreted to blood" NA NA 26000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA040442: AB_2676988" "prognostic favorable (6.55e-4)" "prognostic favorable (7.90e-4)" "unprognostic (9.37e-2)" "prognostic favorable (9.17e-6)" "unprognostic (2.38e-2)" "prognostic favorable (5.85e-5)" "unprognostic (1.00e-2)" "unprognostic (8.66e-2)" "unprognostic (2.84e-3)" "unprognostic (7.93e-2)" "unprognostic (5.05e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (4.37e-6)" "unprognostic (7.64e-2)" "unprognostic (3.38e-1)" "unprognostic (4.45e-1)" "unprognostic (7.62e-2)" 18.0 3.6 1.3 24.2 1.6 1095.6 5.7 2.8 5.1 4.5 1.7 5.7 5.9 4.6 4.8 5.4 10.4 17.7 5.6 1.5 1.4 5.4 12.7 49.3 73.4 2.4 1.4 2.5 3.9 1.0 2.2 4.4 2.0 4.3 5.1 0.2 6.6 2.0 1.9 4.5 13.9 5.0 1.6 148.1 8.7 1.7 1.6 17.3 5.6 4.4 16.4 19.2 5.2 1.4 0.3 0.6 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.3 1.7 0.0 0.4 0.0 77.8 204.6 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 2.8 0.0 0.2 2.0 212.1 0.1 0.0 0.2 0.5 7.7 0.1 0.0 0.1 0.3 0.2 0.0 0.1 1.0 0.1 0.0 13.3 0.2 0.1 0.8 0.2 0.5 0.1 0.1 0.2 0.1 380.4 0.1 74.3 3.0 10.4 1287.0 3.4 720.2 3.7 186.8 904.7 28.4 3.9 38.8 531.2 342.2 655.3 3.5 7.2 123.0 600.8 1.3 1.6 2.8 5.1 1.5 1.4 2.4 1.4 2.0 1.6 1.6 1.4 8.1 9.6 14.1 0.0 14.5 22.8 0.3 0.0 0.0 0.0 2.5 2.4 1.4 4.3 0.6 0.0 0.0 0.2 1094.4 0.3 0.0 1.3 0.0 1.3 0.7 3.2 0.0 46.7 0.0 3.7 0.1 5.2 11.2 1.2 60.0 0.0 11.0 3.8 1.4 0.0 0.0 0.1 0.0 16.2 541.7 0.0 0.0 61.9 24.9 1.9 659.7 0.0 1385.2 0.0 0.1 0.2 0.1 0.0 90.9 0.1 0.4 2.3 2.2 0.0 0.0 2.2 3.6 0.0 0.2 0.5 23.9 1.1 544.5 0.0 0.6 0.6 CST9 "CLM, CTES7A" ENSG00000173335 "Cystatin 9" Q5W186 20 23602410-23605917 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "breast: 1.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 37 "breast cancer: 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA029190 Uncertain "Secreted in female reproductive system" NA NA "Cluster 5: Breast - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA029190: AB_10602804" "unprognostic (2.06e-2)" "unprognostic (2.21e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679803-79754510 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 113.1;Late spermatids: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: AB_2732155" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favorable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 9.3 7.4 3.8 7.2 3.9 13.7 8.9 3.3 4.2 7.8 4.1 11.1 7.2 10.4 1.4 10.7 8.1 4.0 7.2 3.3 3.3 7.9 9.5 9.3 8.7 5.3 4.2 5.0 9.0 3.3 6.9 4.2 4.0 8.2 3.1 1.5 9.5 3.9 11.9 20.5 10.9 3.1 3.3 13.5 9.9 22.2 4.0 6.5 8.0 3.1 3.7 9.6 8.6 4.4 13.4 14.0 7.7 11.0 6.0 5.0 25.9 9.6 6.1 7.6 7.5 9.4 8.0 17.2 4.2 5.6 9.1 16.4 6.6 8.8 3.1 16.9 12.4 8.5 6.6 12.9 8.7 37.6 20.5 8.4 8.3 8.1 3.8 4.6 9.2 12.2 11.2 8.1 3.0 11.5 25.4 29.5 12.7 4.2 19.1 20.7 10.1 20.0 5.6 13.1 12.0 12.4 10.2 9.8 13.9 5.8 8.0 21.7 12.9 12.9 19.4 5.3 9.7 7.4 27.6 16.1 11.0 18.8 9.3 0.0 0.4 3.2 0.5 0.4 0.4 0.2 0.4 0.8 0.6 0.1 0.5 0.3 1.0 1.1 0.4 0.1 0.1 0.2 3.8 3.9 3.3 4.2 3.3 3.3 5.3 4.2 4.0 3.3 4.0 4.4 7.4 0.0 4.1 3.6 9.2 8.5 5.0 4.0 11.4 9.5 7.7 6.5 3.8 4.3 4.5 3.7 14.6 8.8 24.2 20.0 1.9 5.4 113.1 18.6 8.0 7.5 6.0 13.5 7.7 7.2 8.0 4.8 19.9 24.0 7.0 7.8 6.4 5.7 8.8 23.5 6.6 16.6 6.1 7.5 9.5 123.2 7.8 13.8 7.2 6.5 6.5 6.5 19.6 3.0 8.9 10.2 14.9 10.5 15.2 11.8 10.0 6.8 9.6 14.8 0.0 5.9 7.4 18.0 10.5 10.5 10.1 19.0 18.3 8.0 11.7 12.6 CTIF KIAA0427 ENSG00000134030 "Cap binding complex dependent translation initiation factor" O43310 18 48539031-48863217 "Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Excitatory neurons: 76.4;Inhibitory neurons: 80.6;Oligodendrocyte precursor cells: 75.9;Oligodendrocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016865, HPA024801" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA016865: AB_1852311, HPA024801: AB_1852312" "unprognostic (5.84e-2)" "unprognostic (5.86e-2)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.86e-2)" "unprognostic (1.95e-3)" "unprognostic (2.77e-3)" "unprognostic (1.35e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-1)" "unprognostic (2.34e-3)" "unprognostic (7.33e-3)" 35.3 20.0 15.7 3.3 13.9 2.0 24.3 10.7 23.2 14.0 0.0 26.0 2.5 21.5 2.6 11.4 16.3 7.5 24.8 16.0 15.5 11.1 24.8 14.3 1.3 20.7 17.4 28.0 9.8 4.6 12.4 4.3 23.3 13.9 1.6 7.4 11.0 5.4 15.8 14.0 9.9 7.0 9.1 6.7 19.6 7.3 19.0 1.4 10.7 4.3 1.0 26.1 12.6 16.7 3.2 3.4 4.5 5.8 11.3 6.0 2.5 15.9 13.2 12.4 11.2 3.5 1.9 0.0 3.5 22.0 5.2 6.7 3.3 9.0 5.3 0.0 2.7 1.4 7.9 8.4 21.6 2.6 4.5 8.4 14.5 7.8 13.8 8.9 8.9 4.1 4.0 9.8 8.0 1.7 0.9 2.0 2.2 3.4 2.8 1.6 5.2 4.2 3.7 4.3 9.6 9.7 5.6 6.0 4.5 3.8 3.8 3.1 18.1 11.4 10.5 3.4 2.9 3.3 4.2 0.0 10.1 1.6 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 13.9 10.7 23.2 16.0 15.5 20.7 17.4 23.3 9.1 19.0 16.7 7.3 35.3 3.7 94.7 1.9 3.3 2.1 3.5 2.8 25.6 11.2 8.4 16.0 5.7 5.6 7.3 16.7 1.9 0.8 4.6 7.9 5.1 11.1 1.7 7.7 8.5 3.5 0.4 76.4 4.8 2.8 13.1 7.1 3.6 4.5 19.5 7.5 23.0 4.2 11.8 80.6 3.5 4.1 6.4 2.7 19.3 25.1 5.0 3.6 30.0 1.5 3.6 3.1 75.9 59.7 5.7 2.7 50.8 4.8 3.0 5.9 5.8 4.7 8.8 6.6 8.8 9.4 2.3 1.8 3.5 2.3 1.2 0.7 34.7 3.3 3.3 CTNNBL1 "C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L" ENSG00000132792 "Catenin beta like 1" Q8WYA6 20 37693955-37872129 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 372.9;granulocytes: 263.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 308.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004742, HPA027906, HPA027907" Approved Enhanced Nucleoplasm,Centrosome,Cytosol No No "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Centrosome, Cytosol" "HPA004742: AB_1847323, HPA027906: , HPA027907: AB_10601362" "unprognostic (2.81e-1)" "unprognostic (3.42e-1)" "unprognostic (8.80e-2)" "unprognostic (1.88e-3)" "unprognostic (1.93e-1)" "unprognostic (2.55e-2)" "unprognostic (1.44e-1)" "unprognostic (5.11e-2)" "unprognostic (1.02e-1)" "unprognostic (3.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-3)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (2.81e-1)" "unprognostic (5.31e-2)" 26.9 16.8 20.9 27.3 22.8 41.8 23.8 21.6 24.8 23.7 23.4 31.8 21.7 27.7 31.1 23.4 25.3 19.8 32.3 22.0 22.4 22.9 46.8 25.3 39.3 22.8 22.3 27.1 17.3 19.7 18.2 22.1 21.7 23.4 23.1 18.8 18.5 30.6 33.3 25.3 25.1 30.6 21.6 54.0 34.8 43.3 22.1 40.1 17.1 20.9 41.2 25.8 20.4 23.6 66.7 60.3 56.7 44.6 40.3 32.8 89.2 41.9 43.7 98.0 86.0 224.8 52.4 73.9 59.6 42.7 94.4 69.8 77.1 98.6 105.3 36.1 38.0 243.0 33.2 110.2 41.8 77.4 308.0 35.1 58.9 55.6 54.8 34.1 59.8 103.8 66.8 29.6 53.5 54.9 127.0 101.4 51.4 74.9 85.8 87.9 109.1 56.3 42.9 55.0 45.1 53.6 72.5 102.3 75.4 52.3 50.6 61.1 44.5 97.4 58.0 64.9 68.8 34.1 46.6 85.5 68.5 48.6 52.7 267.9 77.7 103.3 51.0 103.0 49.1 88.9 49.9 53.8 110.3 83.4 49.8 53.6 16.9 79.9 109.6 86.9 66.2 71.3 20.9 22.8 21.6 24.8 22.0 22.4 22.8 22.3 21.7 21.6 22.1 23.6 28.6 28.9 26.4 21.2 40.0 22.8 32.9 40.7 13.1 26.1 13.0 13.2 39.8 17.2 34.1 18.4 18.8 147.8 40.4 21.1 37.2 34.8 372.9 24.2 24.9 32.5 20.9 43.7 31.6 34.7 69.4 28.7 48.4 21.6 263.6 34.4 44.3 45.2 49.3 18.5 35.6 27.3 42.7 36.0 35.5 131.2 34.2 44.5 26.6 14.0 89.8 32.1 40.2 30.7 39.8 31.9 21.5 33.4 21.6 22.3 34.7 43.1 26.1 25.8 19.7 25.4 48.0 79.4 45.2 10.7 22.4 52.9 38.8 23.7 24.2 20.6 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 368.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 445.6;Proximal enterocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 856.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" NA NA 28000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 80.4 368.3 56.8 75.3 58.1 75.6 61.9 63.6 65.6 47.6 96.0 178.6 100.9 55.1 39.0 60.4 39.3 89.7 97.2 59.7 63.8 188.1 95.7 90.9 61.6 62.6 59.1 62.2 52.9 104.4 43.8 76.4 61.4 38.5 170.4 44.0 61.3 48.4 56.0 95.2 109.2 67.3 59.4 108.5 63.3 33.5 70.2 23.0 47.4 61.7 58.8 82.8 49.2 68.4 111.9 114.1 17.6 89.2 856.5 438.6 47.0 150.3 424.0 169.6 217.5 214.4 291.8 24.1 176.2 299.9 638.1 168.6 55.9 105.6 95.7 47.6 53.6 54.3 53.4 375.9 187.3 98.0 240.9 349.0 123.6 107.9 22.5 421.9 190.1 28.2 61.0 355.1 186.9 232.1 25.8 82.4 19.4 172.6 272.1 37.8 107.3 135.7 138.2 96.7 36.9 37.8 263.2 450.3 444.4 51.5 108.5 141.8 172.5 335.0 76.2 178.9 123.7 162.1 238.5 15.7 599.3 128.6 142.4 480.7 305.9 530.5 44.9 168.8 185.5 42.0 75.6 78.3 102.4 25.7 26.6 39.8 152.4 81.2 120.1 40.6 155.4 378.1 56.8 58.1 63.6 65.6 59.7 63.8 62.6 59.1 61.4 59.4 70.2 68.4 53.7 35.3 32.6 26.1 38.2 24.2 38.9 88.8 17.6 58.4 18.4 15.9 12.6 65.8 64.1 71.7 60.5 104.1 27.5 445.6 39.2 246.0 3.3 22.3 39.5 56.0 54.0 22.1 20.4 166.4 109.2 86.8 29.6 62.4 9.5 50.8 102.1 67.9 297.1 47.1 25.2 74.5 95.6 177.1 25.1 4.8 32.9 273.1 112.1 12.2 135.6 86.6 37.0 7.1 10.2 135.0 216.0 27.4 41.9 18.6 301.8 245.8 34.2 46.1 26.3 33.7 54.5 15.3 31.9 24.0 22.9 144.1 49.1 91.3 113.9 36.2 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1475.9;Hofbauer cells: 3763.5;Macrophages: 1512.6;Proximal enterocytes: 1699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 2596.6;hTERT-RPE1: 2780.1;SK-BR-3: 2488.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 318.6 734.6 147.0 204.9 181.9 499.0 244.0 186.0 156.5 270.8 672.7 298.0 387.6 170.7 82.8 319.4 171.6 438.4 444.1 187.8 223.6 691.6 464.8 539.6 241.0 247.6 206.6 130.7 284.8 137.3 131.5 180.7 228.6 138.2 153.4 48.3 422.1 231.7 590.3 340.9 398.3 105.0 188.9 442.0 287.2 88.9 334.4 78.1 182.1 178.2 123.1 296.4 307.5 367.1 204.6 578.9 51.4 246.2 586.5 206.3 112.1 149.4 362.2 161.8 182.8 147.5 2596.6 49.2 376.8 285.8 1265.6 1072.2 63.7 142.6 35.8 206.7 222.9 70.4 92.5 196.5 736.2 171.4 787.7 350.9 621.6 82.5 136.9 2780.1 128.2 62.1 89.2 267.6 263.3 832.6 47.0 110.9 153.1 719.7 247.9 62.5 72.5 191.2 586.6 610.8 84.2 94.8 173.3 2488.5 535.0 68.6 1022.8 232.6 170.3 556.8 92.9 79.0 216.7 432.0 382.3 26.8 867.7 468.6 509.6 211.2 578.7 170.1 156.5 309.9 90.6 28.8 72.1 110.3 144.5 18.8 82.5 107.4 319.5 192.3 265.2 120.3 89.2 489.1 147.0 181.9 186.0 156.5 187.8 223.6 247.6 206.6 228.6 188.9 334.4 367.1 139.3 112.2 228.6 48.3 62.8 72.0 223.5 473.2 71.7 168.6 108.9 113.8 251.9 314.5 459.5 548.1 110.5 211.7 156.1 1475.9 109.5 911.4 3.3 118.1 67.4 128.3 159.6 132.6 18.3 370.1 165.0 157.0 237.5 203.4 474.3 119.4 695.7 678.9 3763.5 264.2 25.2 418.2 498.5 1187.8 67.5 14.6 108.4 1512.6 227.7 20.6 382.6 179.0 256.4 27.2 42.2 392.3 832.5 128.2 122.5 111.7 1699.4 311.8 270.3 102.1 111.7 70.7 135.2 26.6 63.5 141.2 82.1 471.3 155.0 96.0 399.1 357.8 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.3;lymphoid tissue: 42.4" "Group enriched" "Detected in many" 9 "dendritic cells: 717.8;NK-cells: 867.2;T-cells: 352.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "gdT-cell: 1376.3;MAIT T-cell: 869.4;memory CD8 T-cell: 892.8;naive CD8 T-cell: 636.3;NK-cell: 2276.1" "Group enriched" "Detected in all" 39 "NK-cells: 2276.1;T-cells: 1376.3" "Group enriched" "Detected in some" 22 "HEL: 156.7;NB-4: 363.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB016345, HPA066903" Enhanced "Intracellular and membrane" NA NA 270000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB016345: AB_626813, HPA066903: " "prognostic favorable (3.06e-4)" "unprognostic (2.06e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.36e-6)" "unprognostic (1.21e-1)" "prognostic favorable (9.89e-4)" "unprognostic (5.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (8.84e-6)" "unprognostic (3.86e-2)" "unprognostic (3.78e-1)" "unprognostic (1.26e-1)" "unprognostic (4.01e-3)" 5.1 2.9 0.8 12.9 0.9 116.3 3.7 1.8 1.6 2.6 0.6 5.6 6.1 6.7 2.8 3.1 4.0 6.2 2.9 0.8 0.9 2.1 6.5 24.0 29.5 1.6 0.7 2.4 1.8 0.5 1.1 3.3 1.2 2.1 6.3 0.0 9.1 3.9 1.3 2.7 6.1 2.7 1.2 42.4 8.3 1.2 1.1 7.8 3.2 0.4 13.9 8.6 2.5 1.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 156.7 0.3 0.0 0.0 11.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 5.0 0.0 9.1 0.2 0.2 1.9 363.4 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 5.6 0.1 0.0 0.1 0.4 0.1 0.3 0.5 0.0 0.2 9.9 0.3 46.4 3.4 4.8 1376.3 4.0 869.4 5.1 145.3 892.8 37.6 3.7 86.0 636.3 25.7 2276.1 5.4 23.3 23.7 809.3 0.8 0.9 1.8 1.6 0.8 0.9 1.6 0.7 1.2 1.2 1.1 1.1 5.1 0.0 4.2 0.0 9.7 4.6 0.4 0.0 1.8 0.0 2.3 2.2 0.4 2.8 1.4 0.0 0.0 0.4 717.8 0.3 0.0 0.3 2.0 0.9 0.9 1.9 0.0 44.1 0.0 0.0 0.2 4.0 12.8 1.1 71.7 0.1 5.7 1.6 1.9 0.0 0.0 0.2 0.0 5.6 34.1 11.1 0.0 9.9 17.8 0.0 6.1 0.0 867.2 0.0 0.2 0.0 0.0 0.0 57.7 0.3 0.0 1.1 0.8 0.0 0.0 1.6 1.9 0.3 1.2 0.8 6.3 0.3 352.6 0.1 0.3 0.3 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 CXCL10 "C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10" ENSG00000169245 "C-X-C motif chemokine ligand 10" P02778 4 76021118-76023497 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.7;Glandular and luminal cells: 23.5;Kupffer cells: 41.1;Langerhans cells: 21.4;Macrophages: 45.7;Plasma cells: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 21.5;intermediate monocyte: 52.4;non-classical monocyte: 36.9" "Lineage enriched" "Detected in many" 15 "monocytes: 52.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.1;BJ hTERT+ SV40 Large T+: 2.2;BJ hTERT+ SV40 Large T+ RasG12V: 2.2;GAMG: 5.1;RPMI-8226: 4.3;RT4: 2.4;THP-1: 3.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 253000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.94e-1)" "unprognostic (5.32e-2)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (7.59e-2)" "prognostic favorable (1.12e-5)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-2)" 4.0 5.9 1.4 95.5 1.5 1.2 20.7 0.9 2.6 13.2 1.2 10.7 11.2 7.1 0.7 8.0 4.1 10.6 4.4 1.2 1.0 7.8 29.0 35.1 68.0 7.4 1.2 3.0 0.9 17.1 2.1 10.3 10.8 43.9 15.9 0.4 20.1 1.8 1.2 2.0 11.2 15.8 3.4 20.3 19.2 3.0 2.6 35.2 3.7 1.1 17.3 45.1 3.7 1.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.1 2.2 2.2 0.2 0.1 2.0 0.2 0.0 5.1 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.3 0.1 2.4 0.0 0.0 0.0 0.4 1.3 0.0 0.1 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.6 0.0 0.0 21.5 0.0 0.0 52.4 0.0 1.4 0.3 0.0 3.5 0.1 0.0 0.0 1.1 0.0 36.9 0.0 0.0 7.6 1.4 1.5 0.9 2.6 1.2 1.0 7.4 1.2 10.8 3.4 2.6 1.5 3.8 0.0 2.2 0.0 2.2 0.9 9.4 52.7 0.6 0.0 2.6 7.0 0.3 1.5 2.8 0.0 0.0 0.1 0.0 2.7 0.0 5.9 2.6 12.5 10.9 8.0 0.0 0.0 0.0 0.0 0.0 6.9 3.1 23.5 1.3 0.0 0.0 0.1 17.3 0.0 0.0 1.0 10.2 41.1 21.4 4.0 0.3 45.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 11.4 6.4 2.6 1.3 0.0 0.0 1.3 12.4 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.9 1.4 CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3435.4;Basal squamous epithelial cells: 3284.9;Breast myoepithelial cells: 1544.3;Fibroblasts: 2220.8;Glandular and luminal cells: 1201.1;Proximal tubular cells: 3662.8;Suprabasal keratinocytes: 2115.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HAP1: 61.6;hTCEpi: 79.9;RPTEC TERT1: 222.2;SuSa: 115.2;U-2 OS: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 33: Fibroblasts - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" 366.1 5.2 77.6 76.2 84.5 0.6 229.1 70.6 102.7 166.3 74.8 152.4 214.0 6.9 66.6 92.9 32.9 19.8 14.0 83.7 73.8 345.6 58.5 7.4 90.7 72.4 91.0 5.5 11.6 1.9 122.0 170.7 72.4 10.1 181.3 17.5 293.5 17.6 81.1 780.3 247.0 6.3 68.7 87.5 107.3 3.7 90.2 26.6 55.2 36.5 128.5 76.6 96.3 77.9 0.0 0.0 2.7 0.0 0.2 0.2 0.7 2.9 0.8 0.2 0.0 0.0 9.1 0.0 2.7 0.1 3.8 0.2 61.6 1.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 79.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 4.0 0.0 0.0 0.2 0.0 1.1 222.2 0.0 1.1 0.7 0.2 0.2 0.0 115.2 0.1 0.0 0.0 0.1 84.9 0.4 0.1 0.3 0.0 0.0 1.4 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 77.6 84.5 70.6 102.7 83.7 73.8 72.4 91.0 72.4 68.7 90.2 77.9 123.8 0.0 1.1 32.7 13.1 3435.4 14.4 276.9 3284.9 245.7 47.5 1544.3 4.1 0.0 5.1 283.3 0.0 35.9 6.1 0.0 563.4 0.0 0.8 45.0 140.8 45.9 0.0 0.0 1.0 0.0 25.4 2220.8 0.5 1201.1 0.0 0.0 43.5 0.2 63.6 6.7 150.8 0.0 240.1 0.9 887.9 1.3 20.8 35.3 439.4 8.4 0.0 6.7 0.0 4.5 4.2 0.1 0.0 0.4 13.3 10.6 0.0 3662.8 2.1 19.0 0.0 889.8 99.2 0.4 5.2 69.3 2115.0 77.2 43.4 0.3 0.1 9.3 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780059-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.9;lymphoid tissue: 158.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.2;Kupffer cells: 456.0;Macrophages: 469.3;monocytes: 396.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 276.3;intermediate monocyte: 261.6" "Group enriched" "Detected in many" 4 "dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3" "Group enriched" "Detected in some" 5 "Daudi: 52.8;NB-4: 64.2;REH: 54.6;RPMI-8226: 210.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" 40.5 28.4 5.5 158.9 5.3 160.9 15.2 6.5 5.5 12.3 12.4 22.3 19.3 9.3 4.3 8.9 9.9 26.2 8.0 4.7 9.1 8.0 27.5 91.5 97.1 15.1 9.6 6.9 4.0 4.4 2.5 54.6 13.3 6.7 30.6 1.7 7.0 9.7 3.7 2.2 22.3 55.5 12.5 89.0 17.2 4.7 11.1 18.3 5.3 5.5 73.2 46.8 2.3 24.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 52.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.4 3.6 0.6 0.0 0.0 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.1 64.2 0.2 0.0 0.3 54.6 0.0 210.4 0.0 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 20.0 0.0 0.0 0.1 0.1 0.2 0.6 1.6 3.4 0.0 8.9 0.0 2.2 276.3 110.5 0.4 261.6 0.5 39.6 0.3 0.4 62.8 32.8 0.3 0.2 19.2 0.6 237.1 90.9 0.9 162.5 5.5 5.3 6.5 5.5 4.7 9.1 15.1 9.6 13.3 12.5 11.1 24.0 2.4 25.6 25.4 0.7 99.9 1.0 0.1 0.0 0.6 0.1 1.0 3.0 11.0 2.8 13.0 1.8 0.0 0.9 82.7 2.0 0.0 0.0 0.6 0.2 0.1 8.1 0.0 5.2 1.6 0.4 1.1 4.4 4.1 0.1 7.6 0.1 5.0 3.2 157.2 1.7 1.6 0.7 0.0 456.0 25.0 0.7 0.6 469.3 1.8 76.8 396.6 0.1 14.4 0.0 0.1 0.1 0.5 0.0 13.6 0.0 0.6 0.5 7.3 0.7 13.1 1.6 1.2 0.0 0.6 1.9 1.3 1.8 7.5 0.0 1.3 0.1 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 CYFIP2 PIR121 ENSG00000055163 "Cytoplasmic FMR1 interacting protein 2" Q96F07 5 157266079-157395595 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.2;kidney: 139.9" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Collecting duct cells: 158.2;Distal tubular cells: 174.1;Excitatory neurons: 117.7;Inhibitory neurons: 147.5;Oligodendrocyte precursor cells: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 202.4;JURKAT: 145.2;MOLT-4: 204.8;U-266/70: 153.6;U-698: 142.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB055519, HPA068106, HPA071459" Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "Plasma membrane, Cytosol" "CAB055519: , HPA068106: AB_2685955, HPA071459: AB_2686400" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-6)" "unprognostic (3.76e-1)" "unprognostic (4.58e-2)" "unprognostic (1.14e-1)" "unprognostic (6.91e-3)" "unprognostic (3.97e-2)" "unprognostic (5.25e-2)" "prognostic favorable (1.18e-4)" "unprognostic (3.81e-2)" "prognostic favorable (3.21e-12)" "unprognostic (2.90e-1)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.49e-2)" 3.2 12.3 61.0 30.8 54.4 55.5 2.8 23.6 103.8 3.1 16.3 8.9 6.3 6.6 25.1 3.8 9.2 8.8 10.4 112.2 25.6 139.9 18.3 12.2 57.1 8.4 33.4 4.8 7.1 64.9 40.1 9.3 6.6 5.8 9.8 35.4 4.0 5.0 7.0 2.8 17.5 5.6 0.0 35.0 20.9 5.3 67.7 85.9 9.9 1.7 55.3 8.3 2.3 37.7 0.3 31.8 47.3 28.8 1.1 1.3 81.5 6.1 9.6 2.5 6.8 6.2 0.6 202.4 14.5 3.4 7.4 0.4 38.0 27.1 5.8 48.8 60.8 28.4 42.3 24.9 4.1 29.1 71.8 5.4 10.9 8.1 0.5 18.8 8.8 145.2 0.4 81.1 7.0 7.7 204.8 5.5 22.3 0.5 8.5 50.6 1.4 102.3 24.5 30.2 70.5 27.4 0.6 28.3 4.6 46.8 19.9 0.8 11.3 2.0 21.4 7.1 5.4 153.6 40.2 142.8 21.4 33.5 11.8 64.8 12.6 90.1 85.9 57.4 61.0 35.8 60.6 75.7 17.8 35.9 63.2 73.2 41.0 53.9 133.7 43.9 53.5 78.0 61.0 54.4 23.6 103.8 112.2 25.6 8.4 33.4 6.6 0.0 67.7 37.7 1.8 3.2 26.9 133.5 76.6 1.1 2.2 2.8 3.4 62.0 3.5 3.4 17.9 8.6 7.4 158.2 16.7 37.2 78.8 6.0 174.1 9.7 15.3 2.8 1.8 2.6 14.4 11.6 117.7 1.6 43.0 3.6 6.1 6.2 2.5 23.1 5.7 30.8 5.3 90.9 147.5 5.6 4.1 6.5 11.4 24.2 1.8 15.7 7.2 23.4 20.3 14.0 101.0 120.6 33.8 1.9 9.9 6.8 41.1 1.3 5.4 55.0 4.7 35.2 0.0 12.2 11.0 3.2 13.1 0.8 1.4 21.1 88.8 2.1 9.1 1.7 CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 94.3;Fibroblasts: 87.6;Leydig cells: 95.7;Melanocytes: 78.2;Sertoli cells: 92.1;Smooth muscle cells: 95.6" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 79.6;Hep G2: 61.7;HHSteC: 120.7;HSkMC: 95.4;SH-SY5Y: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" 79.6 20.8 10.1 12.0 10.7 1.7 55.1 20.6 13.6 27.7 14.1 27.1 21.1 19.6 4.6 12.8 20.4 13.2 104.4 9.5 15.8 12.4 19.0 27.8 7.2 17.5 26.0 13.8 12.8 11.7 10.9 8.9 26.8 29.9 9.3 77.6 14.2 11.0 19.3 19.5 26.6 5.9 10.1 12.2 22.9 5.3 14.3 5.3 50.1 9.6 2.6 50.7 25.6 9.8 0.2 1.1 1.8 0.4 79.6 23.1 26.1 0.7 2.0 0.3 0.9 0.0 0.3 0.2 24.1 2.4 0.3 0.7 0.1 33.7 0.1 0.1 0.2 0.4 0.4 61.7 120.7 0.0 0.0 95.4 7.2 2.5 2.5 0.4 0.3 0.8 0.3 0.1 1.2 0.8 0.2 0.4 0.3 0.0 1.4 0.5 0.3 0.2 0.4 0.1 0.6 129.8 0.1 0.0 2.7 5.9 0.2 0.6 0.2 3.1 1.6 0.3 0.0 1.2 0.3 0.3 0.2 0.3 9.9 0.0 0.1 0.1 0.2 0.1 0.1 1.6 0.1 0.0 0.1 2.2 0.2 0.5 0.9 1.0 0.0 0.0 0.2 0.2 10.1 10.7 20.6 13.6 9.5 15.8 17.5 26.0 26.8 10.1 14.3 9.8 94.3 3.2 2.0 2.0 3.5 10.8 1.3 17.3 3.4 38.5 1.4 5.7 6.1 0.0 6.7 0.0 0.0 1.4 1.9 0.1 0.0 0.8 0.7 2.9 4.2 23.1 0.0 0.0 2.4 0.2 0.6 87.6 1.5 0.7 0.0 0.2 2.2 1.2 0.4 8.4 12.3 0.0 0.0 0.0 13.3 2.5 95.7 2.6 78.2 3.7 0.0 22.1 0.0 1.0 1.0 0.1 0.0 23.3 0.6 0.8 0.0 0.2 21.1 12.9 92.1 21.8 95.6 1.6 1.4 0.7 6.7 2.9 2.6 9.2 0.0 1.0 CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;skin 1: 31.4" "Group enriched" "Detected in many" 4 "Leydig cells: 75.8;Peritubular cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 9.8;HaCaT: 14.8;RH-30: 18.4;U-2 OS: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" No No "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" 26.2 4.3 12.0 1.9 3.3 0.1 15.0 12.3 7.0 5.0 0.4 3.2 3.7 2.5 1.5 3.9 5.5 1.1 8.5 6.7 1.3 8.8 1.0 2.7 4.9 48.0 10.4 4.5 0.6 0.8 9.3 3.3 49.9 2.6 1.2 4.2 9.9 7.3 5.9 31.4 4.7 1.6 0.0 3.5 1.2 13.8 0.7 19.3 14.4 2.3 2.9 3.2 4.2 3.5 0.6 5.9 0.0 0.1 9.8 4.0 5.9 0.9 0.1 0.2 0.2 1.8 0.5 0.0 0.5 0.7 3.0 14.8 8.5 0.0 0.1 0.0 2.7 0.0 7.0 0.9 0.2 0.0 0.3 0.0 0.5 0.0 0.3 3.0 1.1 4.0 0.6 0.1 0.9 2.9 0.0 0.1 0.0 0.1 1.0 0.1 18.4 0.0 0.0 1.3 0.6 0.1 3.0 0.0 3.5 1.2 0.3 0.9 0.0 1.6 19.3 9.0 3.0 0.1 1.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 3.3 12.3 7.0 6.7 1.3 48.0 10.4 49.9 0.0 0.7 3.5 2.4 0.0 0.0 2.0 1.2 14.7 1.1 0.8 0.6 0.2 2.3 0.8 1.4 4.3 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.2 4.1 0.2 0.2 19.0 1.8 5.3 5.3 0.0 0.9 15.6 0.0 0.3 0.0 1.5 34.6 0.8 0.1 0.0 0.7 0.0 0.0 6.1 19.1 9.6 75.8 0.4 7.2 0.0 0.0 7.4 0.0 2.0 0.5 0.4 1.5 229.9 0.0 0.5 0.2 0.1 0.2 0.3 0.0 5.7 20.7 1.5 3.8 1.6 9.7 0.1 0.8 7.5 0.1 0.4 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 242.2" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 1227.5;Club cells: 405.1;Respiratory ciliated cells: 763.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 286.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA004331: AB_1078616" "unprognostic (2.29e-2)" "prognostic favorable (5.99e-4)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (8.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (6.12e-2)" "unprognostic (5.46e-2)" "unprognostic (7.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-3)" "unprognostic (6.69e-3)" 81.8 4.9 0.3 0.0 0.3 0.0 62.0 0.2 0.6 13.4 1.2 14.6 1.3 9.5 1.7 44.0 48.0 0.5 40.2 0.2 0.3 2.4 0.1 242.2 0.5 0.3 0.3 1.7 3.4 0.7 9.3 1.2 0.3 22.7 0.7 0.0 16.6 15.8 24.0 42.7 15.2 0.1 0.3 0.4 11.5 0.5 0.4 3.1 22.3 24.6 15.2 81.7 30.5 0.3 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.6 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 286.7 0.1 0.0 0.0 11.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.6 0.2 0.3 0.3 0.3 0.3 0.3 0.4 0.3 60.8 1227.5 89.3 0.0 0.0 0.5 139.6 111.5 36.5 0.0 2.0 1.5 6.4 1.5 405.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.7 93.8 12.5 23.5 0.0 0.0 0.1 0.0 0.2 47.9 1.1 8.5 6.3 0.0 1.4 0.0 0.6 0.0 0.1 0.0 48.8 0.0 0.3 0.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 6.9 0.0 1.1 763.9 0.0 0.0 3.0 23.3 0.1 0.1 71.4 4.1 0.8 1.8 0.0 0.0 163.0 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 CYSTM1 "C5orf32, ORF1-FL49" ENSG00000120306 "Cysteine rich transmembrane module containing 1" Q9H1C7 5 140175156-140282052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 1317.5" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2568.9;Gastric mucus-secreting cells: 2148.3;Late spermatids: 1327.7;Pancreatic endocrine cells: 1331.5;Proximal tubular cells: 1301.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 425.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 425.2" "Cell line enhanced" "Detected in all" "OE19: 773.7;RPTEC TERT1: 364.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050930 Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA050930: AB_2681278" "unprognostic (7.39e-2)" "unprognostic (3.68e-2)" "unprognostic (4.46e-2)" "prognostic favorable (1.31e-4)" "unprognostic (5.38e-2)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-4)" "unprognostic (2.26e-1)" "unprognostic (1.12e-1)" "unprognostic (2.73e-1)" "unprognostic (2.53e-1)" "unprognostic (2.24e-1)" "prognostic favorable (9.69e-5)" "unprognostic (7.63e-2)" "unprognostic (2.23e-1)" "unprognostic (4.67e-2)" "unprognostic (1.14e-2)" 86.3 187.3 111.3 53.7 112.6 161.2 61.1 114.2 131.5 48.5 148.6 184.3 320.5 36.6 53.9 28.3 139.6 150.8 114.6 110.2 121.1 264.8 74.4 96.6 23.4 117.9 117.4 29.1 141.3 128.6 53.9 64.6 119.3 31.3 166.2 35.2 81.7 41.7 293.5 23.8 168.0 60.0 112.7 33.4 1317.5 35.7 116.4 31.7 87.2 360.0 20.9 158.1 21.9 112.5 68.5 118.8 10.1 65.8 152.5 118.2 51.0 26.7 77.1 34.5 67.8 142.0 115.1 28.4 92.2 44.8 180.1 42.8 55.7 70.8 27.5 54.3 74.6 2.7 50.4 92.3 119.1 9.1 63.5 31.4 92.2 42.2 77.0 62.7 67.5 91.1 48.7 68.4 8.2 66.2 31.4 16.6 16.4 773.7 44.5 7.0 12.4 51.4 364.9 284.0 25.4 16.6 45.8 28.8 280.6 33.3 96.9 27.0 16.0 17.0 17.1 12.8 31.8 62.5 48.6 26.4 87.9 8.9 32.8 15.6 32.4 22.4 4.3 37.3 8.1 18.2 11.5 7.2 41.3 14.4 3.1 4.8 425.2 4.5 39.1 64.0 17.2 16.4 111.3 112.6 114.2 131.5 110.2 121.1 117.9 117.4 119.3 112.7 116.4 112.5 259.9 317.3 115.2 34.6 52.8 169.5 525.6 252.8 51.2 5.6 85.5 77.8 107.2 424.7 186.1 573.8 2.1 422.8 42.8 1024.7 2568.9 674.9 444.3 469.0 60.8 147.8 435.8 47.4 10.6 846.6 53.6 174.0 2148.3 218.9 119.2 9.4 120.0 88.5 205.2 11.8 12.5 285.8 205.4 45.3 150.0 1327.7 101.5 77.1 394.8 13.1 105.5 153.3 3.1 4.5 11.1 1331.5 1148.5 116.6 37.4 365.1 727.1 1301.6 576.5 18.8 144.7 115.6 190.6 208.6 81.4 28.4 113.7 393.1 53.9 30.2 429.3 736.7 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 CYTIP "B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP" ENSG00000115165 "Cytohesin 1 interacting protein" O60759 2 157414619-157488961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 105.6;lymphoid tissue: 114.3" "Cell type enhanced" "Detected in many" "B-cells: 240.4;dendritic cells: 244.3;Langerhans cells: 552.9;Macrophages: 164.0;monocytes: 490.1;NK-cells: 181.3;Plasma cells: 392.5;T-cells: 366.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 54.6;HDLM-2: 44.3;Karpas-707: 146.4;RPMI-8226: 46.9;U-266/70: 246.5;U-266/84: 99.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA007191 Approved Approved Nucleoplasm,Cytosol No NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA007191: AB_1855801" "unprognostic (3.61e-3)" "unprognostic (7.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (9.12e-4)" "unprognostic (5.71e-2)" "unprognostic (1.36e-3)" "unprognostic (9.13e-2)" "unprognostic (1.19e-1)" "unprognostic (6.12e-2)" "unprognostic (7.41e-2)" "unprognostic (1.87e-2)" "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (5.49e-2)" "unprognostic (5.43e-2)" "unprognostic (3.78e-2)" 9.2 2.7 1.4 70.0 1.7 105.6 7.7 1.5 3.7 5.7 4.0 12.8 27.3 3.2 2.1 6.9 3.4 11.8 4.1 1.4 1.9 5.2 12.3 26.1 91.5 3.1 1.8 1.5 3.4 0.9 1.4 4.4 2.6 3.3 14.6 0.5 14.3 3.9 1.1 2.8 23.1 7.0 2.5 42.2 41.6 2.5 2.3 53.6 4.0 2.2 114.3 20.8 3.7 3.2 0.2 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.4 54.6 0.1 0.6 0.0 0.1 0.0 0.0 0.1 44.3 0.0 0.3 0.0 0.0 0.0 7.8 6.4 0.0 0.0 0.2 0.0 4.0 0.0 0.2 0.0 146.4 0.7 0.0 0.0 6.3 0.3 0.8 0.1 0.0 0.1 46.9 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 2.0 0.2 246.5 99.8 24.1 2.4 6.8 0.0 248.9 37.6 109.9 121.8 122.5 122.5 91.5 127.9 115.7 56.1 91.6 205.5 161.0 203.6 90.2 247.9 28.1 136.5 154.8 1.4 1.7 1.5 3.7 1.4 1.9 3.1 1.8 2.6 2.5 2.3 3.2 3.2 3.2 12.2 0.0 240.4 20.9 1.0 0.0 0.6 0.0 24.4 2.5 2.1 5.7 1.3 1.8 0.0 0.7 244.3 0.6 15.6 0.3 1.4 0.3 0.4 4.5 1.8 14.9 0.1 1.9 13.6 6.4 29.0 0.8 7.0 0.0 6.8 1.7 25.2 0.0 0.1 3.7 0.0 86.1 552.9 2.0 0.0 164.0 83.6 12.2 490.1 0.0 181.3 0.0 0.0 0.3 0.3 0.0 392.5 0.7 0.4 1.1 0.0 0.1 0.0 1.5 4.5 0.0 0.6 1.2 17.8 3.0 366.6 0.0 3.8 0.5 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.9;Oligodendrocytes: 27.2;Smooth muscle cells: 22.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 10.5;SH-SY5Y: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" 9.1 3.3 42.1 5.9 42.0 1.4 5.4 41.1 54.4 34.7 3.6 53.9 3.9 48.2 14.3 7.4 37.4 7.2 27.5 48.6 33.4 5.9 2.6 14.0 1.1 45.4 40.1 17.0 1.1 1.9 4.1 1.7 39.9 19.7 6.7 5.8 1.7 24.6 2.2 4.1 13.0 31.6 34.7 6.8 18.0 18.7 46.3 0.5 4.8 2.9 0.9 39.0 15.9 58.0 0.2 0.2 5.6 5.3 1.9 1.5 0.5 3.1 5.2 1.0 1.5 0.2 0.3 0.5 2.0 10.5 1.0 0.3 3.6 0.1 1.0 0.3 1.9 1.2 0.8 0.2 2.7 0.1 2.1 4.9 0.1 1.3 0.1 0.6 0.4 0.7 1.8 1.8 0.9 0.4 0.2 1.4 2.2 0.0 0.8 4.6 1.3 0.3 0.2 0.3 2.1 24.6 0.4 0.2 0.4 5.7 0.4 0.5 0.4 2.6 3.2 2.6 0.5 1.6 0.5 0.8 0.5 0.8 1.9 2.6 0.3 0.3 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.5 0.2 0.2 1.6 0.7 0.2 0.3 0.2 0.1 42.1 42.0 41.1 54.4 48.6 33.4 45.4 40.1 39.9 34.7 46.3 58.0 1.9 6.4 5.5 13.7 0.2 2.3 1.5 0.0 0.0 16.5 1.0 2.4 17.8 1.5 0.7 0.0 2.1 5.4 0.5 0.3 0.0 0.0 23.9 0.4 9.3 3.1 1.8 0.0 9.2 0.0 2.6 7.4 0.0 0.8 6.3 0.5 1.8 0.2 1.1 1.7 16.7 0.2 2.0 1.6 9.2 8.6 7.8 1.4 3.6 7.5 1.2 9.2 2.1 15.1 27.2 0.1 1.2 14.7 0.1 1.0 0.2 0.3 0.2 6.3 6.6 2.3 22.9 2.3 2.5 0.4 3.3 9.9 1.0 4.3 0.2 1.0 DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 87.1;Pancreatic endocrine cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" 59.4 9.3 44.8 17.6 52.5 6.4 36.5 19.3 71.7 59.7 18.6 67.6 9.5 84.4 10.2 30.9 44.7 24.4 39.7 70.1 45.4 52.0 4.0 24.7 9.0 33.8 25.4 34.8 16.9 17.1 45.8 7.1 32.3 29.7 5.9 5.5 33.1 23.9 27.6 36.6 25.0 28.6 24.0 14.2 47.4 27.0 39.7 14.6 33.4 9.0 4.4 61.0 33.1 35.5 17.4 56.1 182.0 319.1 42.4 66.2 56.5 198.6 50.3 113.4 94.5 193.9 59.0 0.3 139.5 155.1 39.0 27.0 80.9 144.0 53.6 5.2 70.4 111.6 72.9 82.0 149.3 43.0 20.5 87.1 37.1 127.3 38.0 113.3 189.4 131.4 54.0 26.0 84.2 25.1 115.1 63.8 264.1 5.7 123.4 338.1 197.2 34.5 85.3 23.7 213.7 289.8 67.0 28.8 111.5 58.4 78.7 42.6 298.6 126.7 169.3 28.2 94.9 6.3 3.1 177.5 53.2 40.5 80.5 9.4 1.4 1.1 10.3 0.8 14.0 0.3 0.3 7.2 1.8 0.4 0.4 5.2 3.2 0.3 0.8 5.8 0.2 2.2 44.8 52.5 19.3 71.7 70.1 45.4 33.8 25.4 32.3 24.0 39.7 35.5 44.2 3.2 1.5 8.1 1.2 10.3 13.7 24.6 9.1 7.0 7.6 9.1 5.1 2.8 11.1 9.2 4.2 1.0 4.5 1.4 1.9 87.1 16.9 8.4 44.0 43.2 40.7 4.8 15.7 43.4 2.8 56.1 11.7 18.4 10.8 49.4 20.7 0.0 1.7 42.1 13.0 2.4 40.7 1.8 8.9 41.6 50.1 6.1 8.8 2.8 2.4 13.4 1.0 5.0 1.0 64.5 0.6 41.0 4.0 16.9 0.6 6.3 5.2 4.5 19.7 10.8 43.4 6.5 26.7 20.1 7.2 0.8 10.4 8.1 3.9 7.5 DBNDD1 "FLJ12582, MGC3101" ENSG00000003249 "Dysbindin domain containing 1" Q9H9R9 16 90004871-90019890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 92.0;skeletal muscle: 48.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 22.8;Ductal cells: 16.0;Exocrine glandular cells: 18.8;Horizontal cells: 30.3;Pancreatic endocrine cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "naive B-cell: 12.9" "Lineage enriched" "Detected in many" 4 "B-cells: 12.9" "Cell line enhanced" "Detected in many" "MCF7: 139.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043018 Uncertain Approved "Nuclear speckles,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" "Nuclear speckles" Cytosol "HPA043018: AB_10794921" "unprognostic (1.07e-1)" "unprognostic (8.40e-2)" "unprognostic (8.70e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-2)" "unprognostic (4.18e-2)" "unprognostic (1.51e-1)" "unprognostic (1.70e-1)" "unprognostic (6.07e-2)" "unprognostic (9.52e-2)" "unprognostic (1.54e-1)" "unprognostic (2.86e-2)" "prognostic favorable (2.75e-7)" "unprognostic (1.03e-1)" "unprognostic (5.67e-1)" "unprognostic (2.44e-2)" "unprognostic (2.00e-2)" 1.8 7.4 47.1 2.5 35.3 0.3 4.4 27.5 60.6 4.1 11.6 2.9 1.6 0.9 10.0 28.2 3.6 3.8 4.6 35.2 40.7 13.3 6.5 3.5 4.7 50.6 55.3 3.1 19.5 9.6 7.7 0.1 50.8 3.8 1.4 7.4 15.5 3.1 48.0 6.0 1.7 1.3 30.3 1.2 7.7 1.0 92.0 1.4 5.2 4.8 5.1 1.7 7.3 38.6 22.8 34.7 3.5 44.7 0.9 0.4 24.7 4.9 6.6 10.5 5.3 32.1 19.7 0.0 2.7 1.1 10.2 24.0 41.3 1.2 10.7 0.1 65.4 0.0 4.4 58.6 1.5 0.3 4.7 1.0 3.3 18.8 0.1 25.2 47.3 0.8 6.7 0.4 4.1 139.7 0.1 33.5 59.5 18.6 13.9 14.5 32.3 0.6 64.2 4.5 51.2 53.0 5.6 5.3 44.8 10.2 34.6 4.8 36.2 7.4 15.1 0.4 24.1 0.3 0.3 0.4 3.5 3.9 20.1 0.0 0.0 0.7 0.0 0.0 0.0 1.2 0.6 0.5 0.0 12.9 2.9 0.5 0.0 0.0 0.0 0.1 0.0 1.0 47.1 35.3 27.5 60.6 35.2 40.7 50.6 55.3 50.8 30.3 92.0 38.6 0.3 3.2 2.0 2.9 6.0 0.4 0.6 0.6 0.0 1.8 13.5 7.5 2.5 22.8 2.0 9.2 0.0 0.2 0.1 1.4 9.8 16.0 0.0 5.7 0.7 1.1 6.0 0.0 6.1 18.8 0.3 0.2 2.6 7.8 0.0 3.4 1.4 2.5 0.3 30.3 3.6 1.5 2.0 0.0 0.7 0.0 1.2 0.1 3.6 2.8 0.2 10.4 0.0 1.5 0.7 15.0 2.9 0.4 0.5 4.3 0.2 10.8 2.7 1.8 0.0 1.4 1.2 0.1 2.0 8.1 1.0 0.0 1.4 0.3 0.8 1.3 DBNDD2 "C20orf35, HSMNP1" ENSG00000244274 "Dysbindin domain containing 2" Q9BQY9 20 45406057-45410610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1300.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 18.8;Gastric mucus-secreting cells: 20.4;Macrophages: 10.7;Smooth muscle cells: 23.6;Squamous epithelial cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "dendritic cells: 18.7;monocytes: 12.5;T-cells: 9.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043991 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA043991: AB_10966212" "unprognostic (6.33e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.79e-3)" "unprognostic (2.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.31e-3)" "unprognostic (8.24e-2)" "unprognostic (5.44e-2)" "unprognostic (3.06e-1)" "unprognostic (3.71e-2)" "unprognostic (2.47e-1)" "unprognostic (1.41e-3)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (2.52e-2)" "unprognostic (3.48e-1)" 71.5 29.7 627.6 33.6 916.1 7.1 59.4 827.6 1054.5 73.6 462.6 160.9 54.5 106.6 41.7 58.7 102.7 33.1 470.5 645.7 709.8 56.3 10.4 63.1 21.3 871.6 808.2 39.1 39.9 65.3 41.3 42.9 853.0 70.2 91.1 34.9 47.7 89.4 316.2 68.6 78.4 100.9 739.9 30.3 82.2 14.4 822.1 23.2 37.2 248.2 27.3 118.7 69.7 1300.9 78.0 13.6 10.8 76.3 6.8 3.0 15.0 44.7 48.4 36.7 24.8 37.2 103.4 1.1 7.7 44.4 13.9 112.1 74.7 4.0 22.4 0.6 43.9 64.5 57.0 34.3 43.1 3.5 94.0 1.2 12.6 13.9 12.8 63.5 25.3 64.8 4.7 1.5 2.9 99.0 5.6 4.9 14.0 50.8 80.0 0.3 1.0 0.7 105.3 1.4 24.8 12.7 15.6 8.4 99.3 7.6 104.0 19.9 41.1 1.5 72.5 48.8 49.5 1.1 1.6 0.3 5.3 0.6 10.9 0.0 10.4 0.0 9.1 12.5 3.3 0.2 8.0 6.8 7.6 0.3 7.4 6.9 0.5 0.8 7.2 18.7 7.4 4.5 627.6 916.1 827.6 1054.5 645.7 709.8 871.6 808.2 853.0 739.9 822.1 1300.9 0.3 3.2 0.5 0.0 3.3 0.0 0.2 0.1 18.8 0.0 0.6 0.3 1.0 0.0 2.5 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.3 0.4 0.2 2.7 0.0 2.1 0.0 0.0 0.0 7.3 20.4 0.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 10.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.5 0.0 3.9 0.4 0.9 0.0 5.3 0.0 0.0 0.6 23.6 0.1 0.0 32.7 0.6 0.0 5.3 0.1 0.4 0.3 DCBLD1 "dJ94G16.1, MGC46341" ENSG00000164465 "Discoidin, CUB and LCCL domain containing 1" Q8N8Z6 6 117453817-117569858 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059667 Approved Approved Cytosol NA NA 22000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA059667: AB_2684099" "unprognostic (1.00e-1)" "prognostic unfavorable (6.44e-5)" "unprognostic (1.08e-1)" "unprognostic (3.23e-3)" "unprognostic (2.47e-1)" "unprognostic (2.29e-3)" "unprognostic (1.53e-2)" "unprognostic (5.94e-3)" "unprognostic (3.74e-2)" "unprognostic (8.99e-2)" "unprognostic (5.69e-3)" "unprognostic (6.33e-2)" "prognostic unfavorable (8.57e-8)" "unprognostic (6.99e-2)" "unprognostic (4.72e-2)" "unprognostic (7.44e-2)" "unprognostic (1.36e-1)" 8.3 3.5 3.7 6.0 4.6 0.6 5.7 3.5 4.9 9.1 2.6 6.6 6.5 5.1 3.3 5.4 2.5 9.1 6.0 5.5 2.7 4.8 9.6 9.9 3.4 3.5 3.6 1.9 6.3 6.8 8.3 8.7 3.7 2.6 6.1 1.0 4.8 2.8 5.5 2.9 8.1 3.8 3.4 3.8 7.6 5.6 3.0 1.2 5.9 5.1 2.5 6.3 5.8 4.3 8.0 17.9 6.3 7.0 10.8 13.5 17.9 45.1 58.1 36.9 27.8 37.9 16.7 0.0 21.8 19.1 45.9 17.9 12.1 19.9 38.7 3.5 9.4 6.8 18.5 62.3 46.7 10.0 5.7 15.4 45.5 33.6 31.4 42.5 52.3 6.7 14.8 6.7 48.9 6.4 0.1 6.7 4.7 21.4 7.4 0.0 1.3 4.7 8.2 9.4 19.0 0.3 33.0 3.6 5.3 9.0 4.7 13.1 38.9 0.0 44.1 12.6 19.8 18.9 5.4 5.3 18.7 9.6 16.5 0.0 0.2 0.0 0.6 0.2 0.1 0.0 0.8 1.2 0.2 0.0 1.0 1.3 0.0 0.4 0.1 0.4 0.9 0.5 3.7 4.6 3.5 4.9 5.5 2.7 3.5 3.6 3.7 3.4 3.0 4.3 16.0 16.0 18.8 5.2 3.0 5.2 3.7 12.3 0.6 8.4 4.8 3.6 5.3 12.8 14.4 5.5 6.2 31.5 4.9 9.5 1.9 7.0 33.0 5.3 15.1 11.0 4.2 3.2 20.8 4.8 6.1 6.6 13.7 7.9 1.3 13.9 17.2 9.6 5.8 5.0 3.3 8.5 6.1 7.0 15.0 10.9 0.9 5.8 8.8 13.1 2.5 1.1 6.2 12.1 11.6 10.4 7.7 0.4 1.6 3.0 11.1 2.7 5.7 3.5 13.1 5.1 27.6 2.2 10.6 6.8 6.0 18.2 5.1 2.1 11.1 5.4 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131382 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.0" "Group enriched" "Detected in many" 6 "Excitatory neurons: 970.6;Inhibitory neurons: 664.8" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 29.0;ASC TERT1: 27.3;fHDF/TERT166: 23.5;GAMG: 34.8;HAP1: 17.9;HSkMC: 25.5;NTERA-2: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB012405: , HPA015040: AB_2669141, HPA015655: AB_2669265" "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 15.5 2.5 22.0 4.0 27.5 0.0 14.2 10.2 45.3 11.8 0.0 4.2 1.1 6.0 4.1 5.4 4.6 7.2 5.5 37.1 37.8 2.8 0.1 2.4 4.2 17.9 13.2 6.1 1.2 1.1 13.7 0.1 53.0 4.1 3.8 17.3 3.4 4.0 2.1 8.4 4.1 19.1 15.7 4.5 3.6 1.3 17.5 1.6 2.8 4.6 2.2 4.3 5.9 18.7 0.0 0.4 6.8 0.0 29.0 27.3 0.0 0.2 0.4 0.2 0.2 0.0 0.1 0.0 0.0 23.5 34.8 0.0 17.9 0.3 0.0 0.0 1.0 0.0 0.8 0.0 1.1 0.0 0.0 25.5 13.0 0.6 0.4 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 37.1 0.0 0.4 0.0 2.0 0.0 1.0 0.0 7.3 4.4 0.0 0.0 2.2 10.4 0.0 0.0 0.0 0.1 6.1 7.6 1.3 0.1 0.0 0.0 2.4 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 27.5 10.2 45.3 37.1 37.8 17.9 13.2 53.0 15.7 17.5 18.7 8.0 9.6 0.6 132.2 0.1 15.2 1.3 1.8 0.0 9.4 7.8 7.0 5.8 0.0 7.9 3.7 4.2 0.0 0.0 0.0 0.0 0.1 1.5 0.7 1.7 3.8 0.0 0.0 970.6 0.0 0.0 82.6 0.5 0.3 0.0 75.5 0.4 0.0 0.1 10.1 664.8 0.0 4.1 0.3 14.7 1.6 20.8 0.7 14.2 44.0 0.0 73.8 0.0 31.2 19.1 0.2 0.0 4.1 0.3 0.6 0.0 0.6 3.1 4.2 6.6 10.8 22.0 1.3 1.4 1.0 9.7 0.0 0.8 30.1 0.0 1.7 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DDRGK1 "C20orf116, dJ1187M17.3, UFBP1" ENSG00000198171 "DDRGK domain containing 1" Q96HY6 20 3190350-3204685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013373, HPA013705" Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" Nucleoli "HPA013373: AB_2091955, HPA013705: AB_2668872" "unprognostic (2.99e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-2)" "unprognostic (1.60e-1)" "unprognostic (6.54e-3)" "unprognostic (2.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.63e-1)" "unprognostic (4.10e-3)" "unprognostic (8.16e-2)" "unprognostic (5.44e-3)" "unprognostic (7.29e-2)" "prognostic favorable (2.01e-5)" "unprognostic (6.80e-3)" "unprognostic (1.43e-2)" "unprognostic (2.48e-2)" "unprognostic (6.90e-2)" 44.6 89.1 43.2 23.8 44.6 24.8 45.5 38.9 65.7 50.8 36.7 43.3 43.4 43.5 20.0 46.0 49.0 22.4 38.4 42.3 36.8 51.2 77.9 51.6 23.6 39.7 38.8 48.9 84.1 54.7 36.6 25.9 39.5 45.7 19.2 43.2 61.7 32.2 58.2 53.0 44.9 19.9 33.5 36.3 63.0 34.8 37.5 18.6 51.3 14.1 17.0 43.5 44.6 48.4 108.5 133.3 32.3 60.6 71.7 27.2 46.6 67.2 31.9 40.6 44.1 105.7 76.7 64.3 53.6 37.5 77.9 118.2 33.5 100.6 14.8 44.0 62.8 54.4 45.6 186.1 97.9 62.1 56.6 42.8 96.2 77.8 55.2 44.8 37.5 45.3 77.0 74.8 26.4 59.2 42.9 115.5 40.1 73.6 60.8 55.9 28.7 98.6 66.7 99.8 71.4 44.1 69.2 192.7 65.6 19.2 82.0 37.6 57.2 64.9 28.8 46.3 104.2 55.8 67.7 27.3 18.0 51.6 38.9 23.1 36.9 45.6 33.3 25.3 32.7 26.9 35.0 35.6 36.8 26.3 30.8 30.5 9.5 24.6 23.2 57.3 36.2 25.9 43.2 44.6 38.9 65.7 42.3 36.8 39.7 38.8 39.5 33.5 37.5 48.4 57.3 44.8 53.9 19.9 35.1 26.3 68.8 119.0 44.3 47.9 77.1 72.3 31.3 91.5 114.3 69.9 64.6 127.5 50.9 105.8 19.6 147.0 42.2 54.8 42.6 54.1 53.4 26.5 28.6 178.8 65.1 49.3 54.0 79.0 27.3 34.8 50.0 125.6 119.3 52.2 13.9 72.2 154.6 60.9 36.0 21.1 55.9 54.2 39.2 7.5 67.8 73.7 64.9 6.0 28.4 145.0 125.3 68.8 60.5 75.7 216.3 80.5 81.6 108.3 65.7 39.1 115.6 38.7 23.6 64.0 38.8 146.0 44.7 70.0 92.7 75.0 DDT "D-DT, DDCT, MIF-2, MIF2" ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23971365-23979828 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 835.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 4869.6;Proximal tubular cells: 1415.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 262.9" "HPA049871, HPA074115" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA049871: AB_2680926, HPA074115: " "unprognostic (1.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (8.09e-2)" "unprognostic (4.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.58e-2)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (7.34e-2)" "unprognostic (3.30e-1)" "unprognostic (3.81e-1)" "unprognostic (2.61e-3)" 125.7 126.7 29.6 15.1 30.6 39.6 99.0 33.1 38.0 69.6 28.7 128.5 44.2 62.6 16.2 119.1 67.3 6.3 167.0 28.9 32.2 218.2 835.9 69.2 13.7 30.7 29.6 83.0 260.9 24.3 47.7 10.7 30.7 109.0 24.2 12.8 82.7 15.7 129.3 89.8 120.7 8.6 30.7 66.3 176.2 39.2 32.9 12.3 80.1 15.7 11.9 86.8 76.4 33.9 107.6 44.8 15.4 34.9 29.0 24.9 92.6 30.4 20.7 26.1 27.1 39.8 30.6 101.9 27.8 16.1 37.7 86.3 38.3 38.1 17.1 43.6 262.9 60.8 58.9 88.3 28.9 136.2 58.8 25.5 28.5 26.3 23.1 27.9 28.7 16.0 56.8 40.2 26.9 53.0 30.1 123.1 46.2 94.4 134.2 65.3 27.0 148.9 46.4 39.2 51.7 49.2 62.8 117.7 95.9 20.6 30.8 42.3 33.1 26.8 59.9 27.8 32.2 122.6 43.9 65.1 53.1 49.7 52.5 63.5 92.9 72.4 46.0 82.8 47.5 75.3 55.3 49.1 87.8 70.7 49.2 48.9 58.3 61.6 79.1 130.4 74.5 78.8 29.6 30.6 33.1 38.0 28.9 32.2 30.7 29.6 30.7 30.7 32.9 33.9 116.9 83.3 86.3 11.1 178.3 138.9 220.5 278.8 176.4 58.4 266.6 379.7 21.3 499.0 153.2 242.8 89.6 202.6 134.1 533.1 718.1 237.2 202.1 150.8 126.4 103.4 259.6 230.2 9.1 375.7 288.2 103.9 163.1 260.3 129.4 97.1 154.9 4869.6 281.0 43.7 11.0 402.8 187.2 240.4 162.2 411.0 117.1 172.2 158.3 9.4 235.8 119.6 135.9 6.0 18.8 233.6 395.1 110.6 166.1 257.5 935.1 1415.8 97.6 100.0 78.9 109.5 127.6 117.9 43.8 280.6 188.0 299.8 140.3 212.5 558.7 291.3 DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90053633 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 290.1;liver: 272.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 399.2;Proximal tubular cells: 485.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol No No 120000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA023160: AB_1847585, HPA023162: AB_1847586, HPA023238: AB_1847587" "prognostic unfavorable (1.49e-4)" "unprognostic (5.76e-3)" "unprognostic (8.37e-3)" "unprognostic (6.13e-3)" "unprognostic (2.01e-1)" "unprognostic (4.45e-2)" "unprognostic (1.68e-2)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.79e-7)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "prognostic favorable (6.06e-4)" 60.2 136.8 12.4 9.6 14.4 24.9 54.4 12.5 14.4 29.4 22.2 65.0 20.2 28.0 14.9 52.6 26.1 7.4 290.1 12.7 13.2 103.5 272.3 34.2 15.0 12.2 13.1 35.5 44.4 13.2 32.6 5.9 12.1 28.6 18.8 8.0 42.8 6.5 121.8 43.3 61.0 9.1 12.5 47.1 44.5 52.3 15.4 10.2 33.0 34.4 13.9 31.1 35.8 12.8 13.1 7.9 19.6 16.1 8.0 17.3 5.2 13.2 12.9 5.9 8.2 2.8 13.4 7.7 5.3 15.1 4.1 6.8 7.7 11.1 11.0 12.6 1.2 18.4 13.6 14.5 11.6 8.7 4.4 12.0 7.0 7.6 10.7 10.1 17.4 16.5 21.3 15.5 20.7 16.3 12.5 7.6 1.5 9.1 24.9 7.4 5.8 13.4 23.4 43.9 1.3 10.6 13.0 81.1 7.7 1.1 10.7 7.4 20.1 11.4 6.2 12.9 6.0 10.5 7.5 12.8 8.6 12.0 10.8 3.9 9.1 6.2 7.1 10.2 7.9 7.4 6.9 8.6 8.8 4.6 8.1 7.8 15.2 3.9 9.3 3.9 9.6 5.8 12.4 14.4 12.5 14.4 12.7 13.2 12.2 13.1 12.1 12.5 15.4 12.8 66.1 76.9 59.4 72.5 52.9 41.3 70.6 180.2 35.3 11.4 51.1 57.4 268.3 82.9 96.4 71.7 2.1 50.2 57.6 119.0 399.2 137.8 165.3 68.2 65.5 60.0 104.8 77.4 27.2 92.5 49.0 60.2 61.2 40.6 50.0 81.3 47.8 244.8 115.1 32.0 55.9 105.9 116.0 95.2 82.7 52.6 85.4 85.1 85.4 29.0 107.1 52.5 74.2 66.9 35.0 87.5 111.6 51.6 67.8 30.3 250.3 485.2 69.0 7.6 72.3 54.5 61.7 157.5 24.6 68.6 41.1 41.0 64.4 135.1 139.6 86.8 DEFB132 "DEFB32, RP5-1103G7.6" ENSG00000186458 "Defensin beta 132" Q7Z7B7 20 257724-261096 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 271.2" "Cell type enriched" "Detected in some" 7 "Collecting duct cells: 11.0" "Group enriched" "Detected in some" 4 "liver cancer: 0.8;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046399 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA046399: AB_10960992" "unprognostic (9.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.54e-2)" 25.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 271.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 1.5 0.0 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100159645 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.0;intestine: 34.8;skin 1: 54.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 82.8;Paneth cells: 77.0;Proximal enterocytes: 298.9;Respiratory ciliated cells: 144.8;Squamous epithelial cells: 86.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 3.5;eosinophil: 6.6;memory B-cell: 10.9;naive B-cell: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 10.9;granulocytes: 6.6" "Group enriched" "Detected in some" 16 "OE19: 69.3;T-47d: 104.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli" "HPA046644: AB_2797231" "unprognostic (8.18e-2)" "unprognostic (3.83e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.94e-7)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "prognostic favorable (1.66e-4)" 0.4 0.1 6.4 1.0 7.2 0.2 6.1 18.3 7.1 4.8 3.6 8.9 24.7 3.3 0.5 37.0 2.0 6.5 0.2 5.1 4.5 10.8 0.9 1.6 0.6 5.9 5.3 1.0 6.9 0.4 3.3 0.4 6.0 2.3 4.5 0.2 8.6 2.1 0.3 54.2 34.8 0.5 4.8 0.8 20.1 1.1 5.3 0.1 2.4 0.0 1.8 6.5 10.1 4.9 0.0 0.3 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 2.4 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.3 0.0 0.0 0.0 0.0 1.1 1.6 0.0 0.0 4.2 0.4 0.3 0.1 69.3 0.0 0.4 0.0 3.6 0.0 1.6 5.2 0.1 0.0 3.1 0.0 0.1 104.4 1.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.5 0.4 6.6 1.6 0.0 0.0 10.9 0.1 0.7 0.7 6.8 0.0 1.0 0.2 0.2 0.0 0.1 0.0 0.7 6.4 7.2 18.3 7.1 5.1 4.5 5.9 5.3 6.0 4.8 5.3 4.9 0.7 3.2 5.0 5.2 3.7 1.8 3.3 22.9 1.2 4.6 24.2 15.2 0.6 37.1 34.8 82.8 0.0 7.7 3.3 24.2 1.9 19.0 1.2 15.3 4.3 3.8 55.3 1.3 0.5 1.5 4.9 1.3 54.6 28.9 9.5 0.9 0.4 0.3 1.6 0.0 0.4 53.5 34.6 0.9 0.6 1.6 0.3 1.5 0.0 3.7 0.5 1.2 12.3 0.0 1.5 2.4 77.0 0.0 3.7 1.7 298.9 0.4 144.8 22.0 0.0 1.1 3.1 3.2 4.0 86.9 15.3 37.4 2.5 0.2 69.6 21.0 DENND1C "FAM31C, FLJ22757" ENSG00000205744 "DENN domain containing 1C" Q8IV53 19 6467207-6482557 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 21.2;intestine: 14.4;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "B-cells: 27.5;dendritic cells: 30.1;granulocytes: 15.9;Hofbauer cells: 14.6;NK-cells: 35.0;T-cells: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 22.5;HEL: 15.1;HMC-1: 44.7;MOLT-4: 14.7;THP-1: 13.8;U-937: 31.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042758, HPA042839" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Centrosome" "HPA042758: AB_10962357, HPA042839: AB_10959898" "unprognostic (5.94e-2)" "unprognostic (1.41e-3)" "unprognostic (4.26e-2)" "unprognostic (1.93e-3)" "unprognostic (1.21e-1)" "unprognostic (1.72e-3)" "unprognostic (3.91e-2)" "prognostic favorable (1.23e-4)" "unprognostic (7.76e-3)" "unprognostic (4.45e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (8.95e-4)" "prognostic favorable (7.51e-14)" "unprognostic (1.37e-3)" "unprognostic (1.27e-1)" "unprognostic (4.53e-2)" "prognostic favorable (5.62e-4)" 2.2 1.0 1.4 21.4 1.3 21.2 1.0 1.5 1.7 0.9 1.5 3.0 4.9 0.9 0.0 1.9 1.3 2.8 1.1 1.4 1.5 1.6 2.1 5.8 32.1 2.4 1.8 0.3 1.3 0.1 0.8 1.8 2.2 1.6 1.2 0.0 3.0 0.5 0.8 1.4 14.4 1.2 1.8 35.1 5.2 0.4 2.8 20.5 1.7 0.3 14.9 3.0 1.3 2.6 0.2 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.5 0.0 22.5 0.1 0.0 0.1 0.2 0.1 0.3 0.0 0.0 0.0 15.1 0.0 1.6 0.0 7.5 44.7 0.0 0.0 0.1 0.0 0.0 0.0 7.4 0.3 9.4 0.1 0.0 14.7 11.5 0.0 0.5 0.0 1.7 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 13.8 0.1 0.0 0.0 0.0 0.0 0.4 2.0 10.6 0.1 31.3 0.0 18.3 19.9 32.8 40.1 32.4 35.0 23.8 28.6 35.0 19.5 18.7 35.7 32.1 27.8 23.8 35.0 11.2 35.6 37.1 1.4 1.3 1.5 1.7 1.4 1.5 2.4 1.8 2.2 1.8 2.8 2.6 0.3 3.2 3.0 0.0 27.5 0.4 0.1 0.0 1.2 0.0 0.6 0.6 1.3 2.8 0.0 1.8 0.0 0.2 30.1 0.5 1.9 0.4 0.7 1.5 0.2 0.4 0.0 5.7 0.4 0.0 0.2 0.7 1.5 0.3 15.9 0.5 1.1 0.7 14.6 0.0 0.5 0.9 0.0 11.6 9.2 0.6 0.0 13.8 3.6 2.8 10.9 0.0 35.0 0.0 0.5 0.3 0.4 0.0 13.5 0.2 2.9 6.2 1.6 0.0 0.0 0.0 0.3 0.3 1.2 1.6 0.1 0.3 34.5 0.7 1.0 0.1 DERL3 "C22orf14, derlin-3, FLJ43842, IZP6, MGC71803" ENSG00000099958 "Derlin 3" Q96Q80 22 23834503-23839128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.6;pancreas: 60.8;salivary gland: 51.1" "Cell type enriched" "Detected in many" 6 "Plasma cells: 1428.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "plasmacytoid DC: 187.4" "Lineage enriched" "Detected in many" 14 "dendritic cells: 187.4" "Cell line enhanced" "Detected in some" "Karpas-707: 26.9;RPMI-8226: 23.6;U-266/70: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB037234, HPA049306" Approved Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB037234: AB_1840802, HPA049306: " "unprognostic (2.01e-3)" "prognostic favorable (8.70e-5)" "unprognostic (9.72e-3)" "unprognostic (7.47e-2)" "unprognostic (9.77e-3)" "prognostic favorable (8.01e-4)" "unprognostic (2.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (4.74e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.76e-13)" "unprognostic (1.53e-2)" "unprognostic (4.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" 2.6 3.2 1.4 4.3 1.4 1.8 5.4 1.3 2.2 6.1 1.9 30.6 10.0 3.7 0.2 4.3 7.1 2.3 7.7 1.3 1.6 5.7 9.1 9.2 9.2 1.8 2.2 2.0 60.8 0.8 8.1 0.8 1.7 3.3 10.9 0.2 51.1 3.8 2.7 0.8 33.7 0.7 1.7 61.6 29.4 24.8 1.7 1.6 14.6 0.2 17.6 3.6 2.3 1.5 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.5 4.8 0.9 0.0 1.4 0.0 1.1 1.3 0.0 0.5 4.8 0.4 4.6 0.0 0.7 3.2 0.6 0.0 0.2 0.5 0.0 0.1 0.1 0.5 0.8 26.9 0.0 0.0 1.3 2.2 1.0 2.3 0.3 4.2 0.0 23.6 0.9 0.3 0.6 0.1 0.1 0.0 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.4 0.1 48.5 6.3 8.3 0.8 6.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 13.8 0.0 0.0 0.0 12.4 0.1 0.0 0.1 0.0 0.0 187.4 0.0 1.3 1.4 1.4 1.3 2.2 1.3 1.6 1.8 2.2 1.7 1.7 1.7 1.5 0.5 0.0 1.1 0.3 183.8 1.8 1.5 3.7 0.6 1.1 19.3 1.8 3.5 1.5 4.1 0.0 2.1 0.8 141.7 2.7 0.0 0.5 113.2 33.8 0.9 1.1 1.8 8.2 0.3 5.8 6.2 2.2 7.7 1.7 2.5 15.7 4.6 7.8 3.4 0.0 1.7 7.9 4.1 2.2 2.1 158.2 2.5 5.4 224.1 1.9 0.5 0.8 0.0 1.0 0.5 1.1 0.5 4.1 1428.8 2.5 0.8 0.5 30.3 0.6 0.0 0.8 2.6 67.0 32.9 1.3 2.0 15.5 17.9 2.1 10.7 2.0 DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 40.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 213.5;Proximal enterocytes: 700.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 18.4;PC-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Nucleoli, Nucleoli rim" "CAB032853: AB_2090798" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (5.10e-2)" "unprognostic (2.78e-2)" "unprognostic (6.88e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-3)" "unprognostic (3.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-3)" 15.0 24.7 4.6 1.8 4.6 5.1 11.8 5.5 5.6 6.1 4.1 16.7 37.0 5.6 1.0 8.6 5.1 2.0 11.7 4.7 4.1 7.9 16.5 6.9 1.8 4.5 4.6 4.3 6.5 3.9 6.5 1.5 4.2 6.6 4.2 1.6 7.4 2.4 11.7 6.9 40.6 1.6 4.1 9.3 8.7 14.7 4.4 2.3 7.4 3.5 1.4 6.7 6.4 4.5 5.2 4.9 2.2 4.1 3.5 1.5 2.9 3.4 3.1 2.9 2.0 11.2 3.1 2.1 12.4 1.9 1.6 4.0 1.8 4.3 0.6 3.7 5.1 3.3 4.2 18.4 2.5 1.0 3.4 2.1 3.2 2.0 2.1 2.1 2.3 7.3 2.9 5.2 1.9 3.7 6.8 4.1 1.1 10.9 21.2 7.7 0.9 3.4 2.8 2.5 2.6 4.2 4.7 5.2 2.3 0.8 2.9 3.3 2.0 1.6 5.6 3.6 2.8 2.3 0.6 0.8 1.8 6.3 3.2 0.0 0.4 0.7 0.2 0.3 0.4 0.1 0.2 0.2 0.5 0.1 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.2 4.6 4.6 5.5 5.6 4.7 4.1 4.5 4.6 4.2 4.1 4.4 4.5 34.0 16.0 19.0 15.7 8.5 8.0 12.5 6.3 4.0 24.6 21.6 16.0 20.8 12.8 8.7 18.4 29.2 11.3 17.6 213.5 1.9 9.4 19.2 12.3 13.7 26.5 23.4 17.7 11.2 11.9 10.3 9.3 48.4 21.3 7.0 23.9 12.5 57.4 18.8 18.5 12.8 93.6 4.1 25.5 11.8 25.8 6.8 22.8 5.4 8.4 9.2 21.3 4.1 17.6 7.0 13.3 113.4 6.8 18.8 8.1 700.1 7.4 5.6 23.6 0.0 11.9 12.3 27.7 17.4 12.3 9.2 16.4 12.3 41.1 108.0 20.7 DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 476.0;breast: 133.6;liver: 331.8;skin 1: 151.5" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Hepatocytes: 116.4;Late spermatids: 64.1;Spermatocytes: 53.9;Spermatogonia: 53.5" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 137.7;neutrophil: 348.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 348.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.4;HDLM-2: 62.5;Hep G2: 64.9;OE19: 124.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 22.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" 476.0 5.1 5.8 19.4 11.7 7.2 133.6 2.9 6.1 2.6 5.3 9.0 14.5 1.2 1.8 24.1 2.1 5.8 11.7 5.7 6.4 3.4 331.8 5.6 4.0 3.7 3.9 1.8 4.6 2.1 1.6 1.5 5.5 2.2 4.9 0.6 10.5 1.6 4.1 151.5 16.5 2.8 3.4 15.0 12.8 38.1 6.9 4.3 8.8 5.6 18.2 21.3 12.6 5.1 13.3 6.4 0.4 11.2 80.4 6.4 1.0 1.3 1.7 1.6 1.0 46.6 13.5 21.1 16.8 0.3 11.9 0.5 1.8 6.5 4.4 62.5 1.2 1.5 4.0 64.9 0.9 7.4 7.2 26.8 33.6 7.3 10.6 4.4 1.2 20.9 1.2 27.6 0.7 8.5 5.1 16.7 3.6 124.0 31.5 0.0 0.1 24.8 1.2 35.8 22.6 1.4 12.3 1.9 2.9 2.7 4.4 26.6 1.6 14.1 7.0 0.3 9.1 16.3 40.0 28.8 10.2 23.7 25.3 19.4 22.1 137.7 0.0 4.4 0.4 7.4 0.4 0.0 6.1 7.6 0.1 0.2 348.6 0.0 5.0 1.8 0.0 5.7 5.8 11.7 2.9 6.1 5.7 6.4 3.7 3.9 5.5 3.4 6.9 5.1 3.2 6.4 5.4 0.3 5.0 1.1 0.9 3.0 0.6 0.9 5.2 7.0 3.5 0.0 2.7 0.0 2.1 0.5 0.3 0.6 0.0 1.7 259.3 3.3 0.2 0.5 1.2 2.7 2.9 0.5 0.1 0.7 10.7 0.2 0.0 2.1 2.9 116.4 2.2 1.7 1.3 4.8 0.0 4.1 13.1 64.1 2.1 4.2 1.8 0.0 4.0 0.4 0.0 0.0 1.0 3.7 2.2 0.7 0.9 2.8 1.2 2.2 3.4 0.0 6.6 0.6 1.0 53.9 53.5 0.3 8.0 0.8 0.5 0.2 3.0 15.7 DGKD "DGKdelta, KIAA0145" ENSG00000077044 "Diacylglycerol kinase delta" Q16760 2 233354494-233472104 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 30.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 143.2;Inhibitory neurons: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 17.3;HeLa: 21.8;U-698: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027530, HPA049101" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA027530: AB_2672320, HPA049101: AB_2680630" "unprognostic (1.84e-1)" "unprognostic (2.19e-2)" "unprognostic (7.76e-3)" "unprognostic (1.92e-2)" "unprognostic (5.69e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (6.03e-2)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.07e-8)" "unprognostic (1.78e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.94e-3)" 5.2 3.4 4.3 1.9 5.5 12.0 5.9 20.5 6.2 4.5 3.2 9.0 1.6 5.9 1.6 2.2 5.7 1.0 7.6 5.8 4.0 2.5 3.6 10.6 4.3 6.5 3.9 8.9 2.7 0.4 3.7 2.9 7.4 5.7 2.3 5.4 5.9 0.5 30.4 3.0 12.9 0.7 4.1 11.4 25.2 9.6 4.4 1.0 8.3 0.9 4.5 5.3 2.6 8.8 1.7 8.5 2.1 1.5 1.5 1.4 3.0 2.4 1.0 0.6 0.5 9.7 1.9 10.3 1.1 2.4 4.5 2.0 2.4 1.0 3.2 17.3 11.3 4.7 21.8 5.8 0.9 11.7 7.2 2.3 2.2 1.1 2.1 1.8 0.8 2.1 7.8 1.8 1.6 3.1 9.2 3.3 1.6 2.8 6.9 14.5 5.7 1.6 0.9 3.3 2.1 2.2 1.4 2.3 1.0 1.8 0.6 5.2 1.0 1.2 3.0 1.2 1.7 7.1 6.2 22.7 0.8 5.6 0.6 1.7 1.6 5.6 2.1 0.6 1.1 4.8 0.5 1.5 0.4 5.0 1.7 2.4 1.2 0.6 1.0 0.4 0.2 1.7 4.3 5.5 20.5 6.2 5.8 4.0 6.5 3.9 7.4 4.1 4.4 8.8 18.9 32.1 46.2 27.1 61.1 8.9 6.4 5.6 4.6 33.8 19.6 11.6 21.0 0.0 13.8 0.0 62.6 14.6 62.0 40.6 0.0 3.6 14.9 23.4 12.5 19.1 2.4 5.0 11.1 4.4 1.2 9.7 143.2 38.1 5.7 13.1 4.6 7.0 6.8 8.4 137.9 32.8 8.2 10.4 13.8 38.7 6.5 28.7 8.8 11.2 17.5 13.9 49.4 43.2 81.5 26.0 13.5 4.5 34.7 17.6 29.6 2.6 4.8 44.3 19.7 49.4 21.2 14.4 29.3 4.5 3.7 2.5 32.5 7.6 20.1 9.9 DHDDS "DS, FLJ13102, hCIT, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471306 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant, Epilepsy, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 256.5;Early spermatids: 99.1;Rod photoreceptor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA026721: AB_1847643, HPA026727: AB_1847644" "unprognostic (1.11e-2)" "unprognostic (5.43e-2)" "unprognostic (5.12e-2)" "unprognostic (9.81e-2)" "unprognostic (6.71e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-3)" "unprognostic (3.81e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "prognostic favorable (4.08e-7)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.22e-1)" "unprognostic (2.95e-1)" 57.3 19.6 12.3 18.9 11.8 12.4 22.7 32.5 14.0 14.6 14.6 37.3 19.1 13.5 38.5 26.3 12.9 15.9 19.8 12.8 13.3 25.5 22.0 13.9 17.6 15.5 16.9 11.4 18.5 39.8 20.9 12.6 18.8 14.1 38.8 37.8 43.3 14.0 13.5 21.2 18.2 18.4 9.0 14.1 23.3 12.3 14.1 14.1 19.1 11.8 20.8 18.1 14.4 12.2 34.2 24.8 20.6 23.8 36.1 28.2 28.4 54.9 33.4 44.0 41.6 37.4 34.6 38.4 33.3 57.2 30.0 24.1 25.4 42.8 42.9 22.7 13.9 38.0 66.9 30.8 39.3 41.4 51.5 40.3 27.6 59.1 32.2 29.4 51.2 26.7 27.3 41.0 39.7 19.4 23.1 20.2 26.3 53.1 36.2 25.3 33.4 31.2 25.4 28.8 24.4 19.4 36.4 38.0 26.6 26.8 29.8 20.9 63.0 30.1 26.3 60.4 32.0 48.1 72.4 39.5 43.0 54.0 26.8 9.4 16.1 9.6 13.8 23.6 9.8 13.2 9.0 9.1 13.6 10.2 7.4 10.9 13.0 10.1 23.1 11.5 8.3 10.5 12.3 11.8 32.5 14.0 12.8 13.3 15.5 16.9 18.8 9.0 14.1 12.2 9.4 9.6 7.8 7.8 13.5 4.6 9.6 12.0 10.8 29.6 9.6 7.4 15.5 15.7 13.8 14.7 256.5 18.3 13.7 76.3 11.7 19.3 99.1 11.6 12.9 11.1 20.9 5.7 26.9 14.5 23.4 11.1 33.6 20.0 19.0 14.4 10.0 13.2 24.5 15.2 28.5 46.3 14.2 11.5 7.1 23.4 10.5 10.5 10.6 10.3 34.4 16.3 14.4 9.0 11.4 17.6 40.3 7.5 18.7 10.6 24.7 29.3 11.5 106.1 0.0 8.4 14.5 13.2 13.5 12.4 5.1 25.4 10.3 15.8 26.0 12.2 DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "intestine: 216.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 317.3;Paneth cells: 154.2;Proximal enterocytes: 527.9;Undifferentiated cells: 148.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" NA NA 42000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 56: Intestine - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Golgi apparatus" "HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209" "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" 10.0 10.5 6.9 5.4 7.9 4.4 10.9 6.7 9.8 9.5 9.0 74.3 216.0 5.7 1.9 14.6 7.3 2.4 17.2 8.6 9.0 21.9 14.8 4.3 2.4 7.4 7.5 5.1 15.4 9.5 13.3 2.0 7.9 8.0 57.1 22.4 10.3 4.5 16.7 14.4 177.0 6.3 6.6 4.7 11.7 17.0 8.2 2.1 11.9 9.9 3.6 6.8 10.5 7.7 13.9 10.0 3.6 13.8 1.2 2.5 10.6 3.8 2.6 11.9 10.7 22.2 10.1 0.8 1.9 4.0 4.8 13.9 11.5 6.7 10.5 7.1 15.2 3.7 10.1 35.6 5.5 3.0 1.2 2.2 7.3 8.6 6.5 1.9 8.8 11.2 36.1 9.3 5.9 12.5 12.6 5.5 4.5 14.2 0.4 15.2 12.8 22.0 9.9 11.4 10.4 4.9 16.0 12.9 33.3 6.6 19.1 3.6 4.8 1.6 18.2 7.6 10.0 14.1 16.7 4.4 6.5 9.3 5.5 0.1 0.1 0.4 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.0 6.9 7.9 6.7 9.8 8.6 9.0 7.4 7.5 7.9 6.6 8.2 7.7 9.1 0.0 1.5 4.2 3.3 4.2 8.9 2.8 4.0 20.7 14.6 13.3 9.6 2.8 2.4 7.3 129.3 7.9 1.4 317.3 58.7 10.7 22.9 10.2 5.0 6.7 12.1 31.5 8.2 11.4 4.7 3.4 8.6 6.8 0.0 5.3 5.3 12.7 3.5 16.8 9.6 72.2 2.0 1.9 4.2 30.5 4.1 2.6 19.6 2.8 3.6 15.8 1.0 4.0 2.0 7.5 154.2 5.3 9.1 11.7 527.9 43.1 3.8 71.0 0.0 5.9 5.9 27.7 6.5 12.0 6.0 7.0 3.1 9.3 148.5 15.2 DHRS3 "RDH17, retSDR1, Rsdr1, SDR1, SDR16C1" ENSG00000162496 "Dehydrogenase/reductase 3" O75911 1 12567910-12618210 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 323.7" "Cell type enhanced" "Detected in many" "Late spermatids: 409.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 86.8;MAIT T-cell: 63.1;memory CD4 T-cell: 46.9;memory CD8 T-cell: 41.0;myeloid DC: 24.0;naive CD4 T-cell: 79.2;naive CD8 T-cell: 50.1;NK-cell: 41.1" "Group enriched" "Detected in many" 5 "dendritic cells: 24.0;NK-cells: 41.1;T-cells: 86.8" "Cell line enhanced" "Detected in many" "A549: 107.4;CAPAN-2: 206.9;hTERT-RPE1: 196.7;SK-BR-3: 104.6;WM-115: 192.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010844 Supported Approved Nucleoli,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Mitochondria" "HPA010844: AB_1847653" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.74e-3)" "unprognostic (1.87e-1)" "unprognostic (3.68e-2)" "unprognostic (2.25e-3)" "unprognostic (5.06e-2)" "unprognostic (3.40e-2)" "unprognostic (5.18e-2)" "unprognostic (1.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "prognostic favorable (2.65e-4)" "unprognostic (5.48e-2)" 150.9 21.6 38.3 18.6 37.8 13.8 115.8 34.8 41.1 89.8 96.3 60.8 50.2 34.6 25.3 117.1 53.9 33.5 73.2 38.0 38.0 87.8 323.7 56.4 18.0 57.2 37.8 38.8 108.4 31.3 48.8 19.6 40.1 169.6 21.2 8.6 67.0 48.2 76.2 71.9 52.5 16.8 40.6 27.0 87.1 20.2 41.3 10.4 121.2 24.7 8.9 73.0 107.0 44.2 18.1 107.4 0.1 42.7 54.9 5.0 11.9 6.2 0.3 0.2 0.4 11.8 206.9 0.1 5.2 57.7 17.6 79.9 21.4 10.6 0.2 0.1 36.3 16.5 11.3 57.3 8.5 0.3 0.3 27.9 13.5 0.3 0.5 196.7 18.0 0.7 24.3 0.3 0.3 3.0 4.4 1.0 6.8 18.5 40.3 0.5 0.1 20.2 0.1 36.6 1.3 2.0 35.0 104.6 6.6 13.2 10.3 4.8 13.5 0.5 2.2 30.3 0.4 3.3 0.2 0.2 23.9 1.4 192.8 9.2 0.8 0.1 86.8 0.5 63.1 0.6 46.9 41.0 24.0 0.7 79.2 50.1 4.7 41.1 1.1 3.0 1.4 48.2 38.3 37.8 34.8 41.1 38.0 38.0 57.2 37.8 40.1 40.6 41.3 44.2 139.5 96.1 55.9 26.8 3.4 25.6 136.0 114.8 59.2 2.0 17.5 22.6 42.3 45.8 93.4 20.2 18.8 34.4 35.5 83.8 23.5 99.3 99.6 69.8 50.2 54.1 25.1 23.6 3.7 163.1 45.0 56.4 32.1 83.7 15.8 2.6 73.5 181.3 67.1 0.0 3.3 33.0 42.7 69.6 8.4 409.5 22.7 43.6 7.2 17.8 11.5 15.3 38.1 1.0 0.6 129.6 69.5 9.8 3.5 76.2 112.6 52.9 82.8 2.4 0.0 10.5 30.8 1.9 1.4 51.7 27.0 26.3 28.3 7.9 33.0 156.8 DIAPH2 "DIA, DIA2, POF, POF2" ENSG00000147202 "Diaphanous related formin 2" O60879 X 96684663-97604997 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.0;Late spermatids: 177.8;Microglial cells: 301.7;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005647, CAB015461, CAB068183, CAB068184" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum, Vesicles" Nucleoli "CAB015461: AB_831223, CAB068183: AB_2665693, CAB068184: AB_2665694, HPA005647: AB_1078657" "unprognostic (5.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (2.16e-5)" "unprognostic (1.58e-1)" "unprognostic (6.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.41e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.12e-4)" "unprognostic (3.39e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (6.44e-2)" "unprognostic (3.11e-2)" "unprognostic (6.99e-3)" "unprognostic (6.08e-3)" 10.7 3.3 3.7 6.4 6.4 17.7 7.0 0.0 4.3 10.6 17.3 8.6 4.3 5.5 3.5 7.7 6.7 5.7 5.4 6.4 3.1 3.1 12.3 8.2 3.8 0.6 0.9 7.7 4.9 7.0 2.0 12.5 1.0 6.1 8.7 3.0 6.6 7.6 12.0 5.3 5.3 7.4 0.2 3.8 7.4 9.4 1.5 6.0 3.9 9.1 3.9 7.4 9.8 1.8 0.0 6.5 3.1 6.3 17.1 28.3 0.0 11.2 11.8 5.9 12.4 5.5 12.3 18.5 8.7 9.7 11.3 0.0 16.6 1.7 7.6 0.5 9.5 0.0 7.4 5.9 14.2 24.3 8.2 14.3 6.0 8.0 24.6 8.0 11.6 13.6 0.0 14.9 11.2 5.3 9.2 10.0 24.4 0.1 9.4 0.0 16.5 0.0 3.4 9.8 0.0 6.3 0.0 3.2 9.0 18.8 2.7 13.2 14.8 12.6 5.8 10.6 7.3 0.2 0.0 15.3 10.7 24.1 7.6 0.0 3.1 3.3 1.1 2.8 0.9 1.7 1.2 1.4 2.3 1.3 0.8 0.7 0.3 0.7 2.5 2.2 0.7 0.6 3.7 6.4 0.0 4.3 6.4 3.1 0.6 0.9 1.0 0.2 1.5 1.8 61.7 32.1 51.1 21.2 18.8 10.8 6.8 11.9 11.4 5.5 9.9 8.1 20.2 15.7 15.0 20.2 0.0 65.2 21.5 36.6 7.9 18.6 80.5 51.2 46.2 31.2 24.6 6.1 171.0 23.4 16.8 35.2 41.8 41.7 7.6 36.1 8.2 26.1 21.0 0.0 90.0 32.3 4.1 29.6 19.3 177.8 45.1 34.7 8.8 301.7 32.7 13.0 10.3 281.0 41.2 38.4 39.3 20.3 11.6 8.0 11.9 9.4 57.1 13.7 26.3 46.7 32.7 7.5 12.9 17.6 18.3 118.3 19.0 19.0 32.5 6.0 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DISP1 "DISPA, DKFZP434I0428, MGC13130, MGC16796" ENSG00000154309 "Dispatched RND transporter family member 1" Q96F81 1 222815022-223005995 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.7;Gastric mucus-secreting cells: 48.4;Inhibitory neurons: 54.4;Microglial cells: 204.2;Oligodendrocyte precursor cells: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 15.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051411 Uncertain Approved "Nuclear bodies" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear bodies" "HPA051411: AB_2681475" "unprognostic (2.10e-2)" "unprognostic (3.31e-1)" "unprognostic (7.00e-2)" "unprognostic (7.81e-2)" "unprognostic (7.82e-2)" "unprognostic (2.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.27e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-1)" "prognostic favorable (5.00e-4)" "unprognostic (4.13e-1)" "prognostic favorable (3.86e-5)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "prognostic favorable (4.16e-4)" "unprognostic (9.69e-3)" 6.8 5.7 1.7 1.5 2.0 0.2 3.0 4.0 2.5 3.2 3.7 9.0 2.6 4.3 2.0 1.9 2.4 4.6 3.9 1.6 1.9 5.2 2.7 9.2 1.1 1.2 0.9 4.5 2.4 5.1 2.5 4.6 1.1 2.4 2.1 1.3 1.9 2.0 4.1 3.3 3.7 4.2 0.7 2.5 5.3 6.5 1.5 1.4 5.2 3.1 1.4 5.4 2.5 2.6 0.9 2.2 5.6 3.8 10.1 6.1 2.4 3.2 2.7 1.1 1.1 2.6 1.6 0.1 4.2 1.5 2.2 0.6 1.6 1.3 1.6 8.1 2.4 1.1 6.3 1.2 4.4 0.2 1.1 4.8 1.9 2.3 0.9 5.8 2.3 1.2 0.0 0.1 3.9 1.5 1.4 0.3 4.0 6.1 1.3 1.7 15.1 0.2 6.8 0.8 1.6 2.5 1.8 0.7 2.3 2.7 2.7 1.4 4.2 2.3 1.5 3.9 3.6 1.2 0.5 0.3 3.2 0.8 5.1 0.3 0.2 0.0 0.7 0.4 1.6 0.5 0.6 0.7 0.6 0.9 0.6 0.5 0.1 1.0 0.2 0.3 0.5 0.4 1.7 2.0 4.0 2.5 1.6 1.9 1.2 0.9 1.1 0.7 1.5 2.6 4.6 6.4 1.7 42.7 3.6 0.5 0.6 1.2 5.7 2.7 3.4 1.5 7.8 7.2 3.3 11.0 0.0 1.4 2.1 1.0 0.0 1.9 2.1 1.9 3.4 4.9 0.0 0.0 47.7 2.8 1.8 5.6 48.4 4.1 0.0 15.8 6.8 3.3 5.9 0.0 54.4 2.6 4.1 1.6 0.9 3.7 1.5 4.1 0.0 204.2 1.4 0.9 5.2 199.6 15.4 1.3 3.1 3.4 0.7 0.7 6.4 5.8 2.7 2.3 0.0 4.0 3.7 2.1 2.3 5.4 1.1 0.8 1.7 2.8 1.6 0.3 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DLAT "DLTA, E2, PDC-E2" ENSG00000150768 "Dihydrolipoamide S-acetyltransferase" P10515 11 112025408-112064404 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 89.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.5;Distal tubular cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003782, HPA040786, HPA062766" Supported Supported Mitochondria NA NA 44000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB003782: , HPA040786: AB_2677136, HPA062766: AB_2684864" "unprognostic (4.57e-3)" "unprognostic (1.75e-1)" "prognostic favorable (6.19e-6)" "unprognostic (7.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (8.68e-2)" "unprognostic (5.36e-2)" "unprognostic (2.93e-1)" "unprognostic (2.23e-3)" "unprognostic (6.25e-2)" "prognostic favorable (1.95e-14)" "unprognostic (5.82e-2)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (6.15e-2)" 24.7 16.5 7.7 13.3 8.3 7.9 14.5 9.5 9.3 11.0 10.4 24.7 18.3 10.0 13.4 19.5 13.0 8.5 69.4 8.1 11.1 33.8 15.5 11.7 16.1 8.3 8.9 9.5 6.8 31.7 8.5 13.1 9.7 14.5 26.0 10.8 16.8 14.8 75.4 10.3 16.5 13.4 8.2 9.9 14.3 9.9 9.4 12.7 20.2 89.4 18.2 14.2 8.1 8.0 18.7 16.4 28.2 34.4 41.6 30.5 26.5 26.6 18.2 34.8 38.7 52.8 56.7 85.4 46.0 28.7 42.6 41.0 65.7 34.2 38.9 27.3 30.2 51.9 17.9 39.2 29.0 64.9 26.6 36.9 37.7 32.0 35.2 24.2 33.9 41.7 88.4 42.6 41.2 16.6 25.4 66.9 30.3 58.6 35.4 45.4 38.0 93.3 64.4 21.4 51.2 27.8 30.7 93.4 20.5 30.9 67.4 42.9 17.8 29.1 29.1 29.1 33.0 11.1 19.4 127.5 7.7 73.0 22.7 9.1 3.8 3.0 4.3 5.8 5.4 5.6 4.9 5.1 5.8 4.0 5.6 5.1 0.3 4.7 6.1 4.5 5.8 5.0 7.7 8.3 9.5 9.3 8.1 11.1 8.3 8.9 9.7 8.2 9.4 8.0 7.6 12.8 14.5 15.3 13.8 11.2 9.2 18.2 14.2 8.1 9.2 5.8 100.5 15.7 13.2 11.0 0.0 21.2 6.4 26.3 74.3 18.7 3.9 15.8 11.6 9.6 17.3 18.1 18.0 11.4 39.6 11.7 11.7 12.1 3.8 13.5 7.5 15.5 18.7 8.4 24.4 17.8 24.4 8.8 7.5 3.2 6.2 9.5 17.8 9.4 16.7 10.4 4.1 11.1 19.7 14.1 9.2 10.9 19.4 7.0 19.0 37.6 30.3 11.1 0.0 14.2 19.9 25.1 18.3 21.1 9.8 17.4 8.5 26.3 26.7 9.3 DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Alveolar cells type 2: 225.9;Excitatory neurons: 208.8;Microglial cells: 317.6;Oligodendrocyte precursor cells: 244.3;Oligodendrocytes: 707.2;Sertoli cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 83.2;U-2197: 98.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017753 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" Nucleoplasm "HPA017753: AB_10600805" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.11e-4)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (8.46e-3)" "unprognostic (6.49e-2)" "unprognostic (2.02e-2)" "unprognostic (3.56e-3)" "unprognostic (2.79e-2)" "unprognostic (7.33e-2)" "unprognostic (1.67e-1)" 52.5 10.6 17.8 8.8 28.7 2.6 29.6 21.8 18.2 13.5 4.8 19.6 5.6 16.1 5.3 6.3 14.7 19.1 21.5 22.9 21.3 13.7 20.4 42.9 3.8 27.8 23.5 9.5 9.0 6.1 5.3 24.2 29.0 6.7 6.2 1.5 5.6 4.2 7.2 7.1 11.5 19.1 18.8 16.4 13.6 4.0 22.5 2.1 15.7 10.3 1.8 15.4 11.1 38.0 0.1 0.7 6.6 0.0 69.4 35.5 20.3 39.3 33.7 40.7 48.6 11.5 6.6 0.0 9.7 51.4 39.4 6.6 4.3 7.4 83.2 0.0 7.2 39.5 0.1 21.7 31.8 0.0 13.7 36.6 0.6 62.6 46.7 43.3 46.7 0.1 2.7 0.0 33.6 0.8 0.0 0.0 0.7 1.4 4.7 0.0 0.0 0.0 19.7 24.4 0.0 2.9 0.0 1.1 31.8 27.4 0.0 0.0 61.7 45.5 18.8 98.7 15.3 0.1 0.0 0.0 31.6 0.3 63.4 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.8 28.7 21.8 18.2 22.9 21.3 27.8 23.5 29.0 18.8 22.5 38.0 171.7 250.0 225.9 177.3 2.3 14.8 2.5 4.8 5.2 0.9 9.3 8.3 37.8 24.3 19.7 3.7 0.0 7.8 0.6 0.4 1.9 3.1 8.4 15.3 36.1 138.4 1.2 25.2 208.8 4.4 2.3 74.2 4.6 27.3 68.2 0.1 193.1 25.7 3.6 13.5 151.8 1.2 0.0 18.6 17.0 4.3 72.4 6.2 24.9 317.6 0.2 1.0 0.0 244.3 707.2 3.0 1.3 36.1 1.9 1.4 6.1 1.9 3.0 1.9 223.5 50.0 138.0 6.2 11.4 1.8 9.2 2.7 3.6 31.1 2.9 1.7 DLD "DLDH, E3, GCSL, LAD, OGDC-E3" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107891162-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 357.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 356.2;Distal tubular cells: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Approved Nucleoplasm,Mitochondria NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA044849: AB_2679111" "unprognostic (2.01e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-2)" "unprognostic (9.27e-2)" "unprognostic (5.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (9.43e-2)" "unprognostic (7.35e-2)" "prognostic favorable (7.58e-9)" "unprognostic (4.08e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-3)" "unprognostic (1.18e-1)" 108.7 98.9 22.7 42.1 23.7 54.0 49.0 27.1 29.1 36.3 35.6 109.0 81.8 45.3 21.2 94.1 34.3 48.5 264.1 23.1 29.5 153.3 112.8 39.3 50.1 27.1 27.4 30.0 49.2 136.7 27.8 43.1 26.6 45.7 99.3 35.0 50.2 50.3 295.0 38.9 71.9 67.7 24.9 38.4 80.5 31.3 25.7 43.2 64.2 357.0 67.5 66.1 32.7 23.4 171.4 134.5 74.8 127.9 104.6 91.4 88.4 96.5 80.8 110.6 86.2 159.5 95.5 165.9 159.6 103.0 177.7 110.9 150.2 135.8 166.1 111.1 88.4 116.9 175.6 116.7 80.3 194.7 116.0 104.8 97.6 116.4 63.4 72.3 134.0 137.0 298.5 119.7 121.8 188.1 161.8 138.9 87.4 206.0 98.2 113.1 117.8 225.9 151.8 250.8 92.3 99.9 156.3 262.1 143.9 149.9 100.5 165.8 87.9 120.7 97.3 238.1 149.4 89.3 187.1 114.6 115.0 204.1 130.2 132.7 63.9 136.0 46.9 81.6 49.4 37.8 46.8 46.8 87.2 38.5 47.9 50.5 39.9 68.1 116.9 29.9 49.0 64.2 22.7 23.7 27.1 29.1 23.1 29.5 27.1 27.4 26.6 24.9 25.7 23.4 26.7 28.9 20.7 14.7 26.3 31.4 42.7 124.7 31.3 47.1 24.0 19.2 356.2 51.5 70.5 79.1 22.9 110.2 27.3 56.1 226.9 69.3 10.2 27.6 26.2 32.2 30.6 53.9 23.9 55.9 62.7 36.3 36.7 28.0 26.6 35.3 26.0 86.8 69.2 21.9 25.3 44.1 114.0 41.0 26.5 7.3 23.3 37.5 37.4 15.9 62.2 36.0 38.1 21.1 16.7 42.6 51.4 42.2 30.7 24.3 60.0 178.9 55.5 45.5 26.3 28.4 44.8 55.2 51.5 48.0 32.4 108.4 29.5 73.7 78.7 39.2 DLG5 "KIAA0583, P-dlg" ENSG00000151208 "Discs large MAGUK scaffold protein 5" Q8TDM6 10 77790791-77926755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 112.5;Glandular and luminal cells: 139.6;Horizontal cells: 186.7;Syncytiotrophoblasts: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "PC-3: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001746 Supported "Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA001746: AB_2666418" "unprognostic (1.36e-1)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (6.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (5.38e-4)" "unprognostic (8.48e-2)" "unprognostic (6.41e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.60e-1)" "unprognostic (8.00e-2)" "unprognostic (3.06e-1)" "unprognostic (5.13e-1)" "unprognostic (6.00e-2)" "unprognostic (2.74e-2)" 11.9 51.8 8.3 0.5 8.1 0.2 19.4 7.7 8.5 24.4 9.4 28.6 0.3 25.1 16.3 19.7 17.7 1.1 7.4 8.1 8.6 8.8 4.6 8.6 0.4 17.2 9.6 19.5 11.1 6.1 33.9 2.4 10.2 31.2 1.7 4.2 16.8 2.9 26.3 36.3 12.5 2.2 10.1 4.1 16.4 6.2 8.6 1.2 22.3 0.9 1.4 20.3 22.2 10.3 5.7 0.1 4.5 4.9 6.8 2.9 2.9 6.3 3.7 1.1 1.1 0.0 3.8 0.0 6.0 3.2 1.9 6.0 2.3 3.4 4.2 2.0 7.5 1.1 0.0 7.0 6.5 0.4 1.5 3.3 8.1 0.2 9.8 8.2 0.4 0.1 3.0 0.0 3.4 2.0 0.6 1.8 4.3 7.0 20.0 4.1 1.4 0.3 4.8 0.0 1.5 4.2 2.7 5.7 2.2 6.1 2.3 1.1 1.9 1.2 9.2 1.2 5.7 0.0 0.7 0.5 1.2 1.2 0.6 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 8.1 7.7 8.5 8.1 8.6 17.2 9.6 10.2 10.1 8.6 10.3 5.2 6.4 5.4 21.2 0.5 29.6 24.2 20.2 12.0 18.3 41.9 28.3 2.8 12.8 13.6 20.2 16.7 112.5 12.1 12.2 0.0 6.7 16.4 55.6 41.7 4.9 2.4 0.0 24.0 5.9 23.6 12.5 8.2 139.6 1.3 49.4 3.3 3.3 13.1 186.7 28.3 10.4 8.2 0.0 3.9 10.2 18.6 1.8 8.8 10.3 0.8 46.4 9.2 19.1 13.6 12.4 7.6 18.4 6.8 25.4 15.2 2.1 34.6 15.3 26.3 24.2 15.1 1.6 7.6 10.8 24.2 171.6 5.5 10.4 10.1 23.5 DLGAP4 "DAP4, KIAA0964, SAPAP4" ENSG00000080845 "DLG associated protein 4" Q9Y2H0 20 36306336-36528637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 213.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054105, HPA056378" Approved Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA054105: AB_2682381, HPA056378: " "unprognostic (1.11e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.73e-6)" "unprognostic (1.23e-1)" "prognostic favorable (9.88e-5)" "unprognostic (1.28e-1)" "unprognostic (2.18e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" 55.4 47.5 39.0 23.5 31.4 7.5 40.3 2.8 45.9 51.7 2.6 71.4 21.2 64.5 12.5 31.7 45.2 26.4 58.4 39.3 12.3 34.3 37.3 60.5 16.6 5.4 18.1 48.4 47.8 13.8 36.4 26.5 10.5 44.7 15.0 25.4 37.8 30.6 130.8 86.8 37.1 42.5 2.8 32.9 36.5 29.3 29.1 14.7 43.3 45.9 14.8 56.2 46.6 20.6 49.9 44.2 53.0 44.1 49.0 79.9 53.2 73.2 66.5 70.0 48.2 67.4 30.9 14.0 38.5 103.3 61.9 46.7 14.3 75.1 51.8 22.5 5.2 31.8 22.7 46.2 70.9 12.9 26.5 52.9 57.0 83.1 57.6 54.2 69.7 19.5 22.5 37.2 53.6 37.0 26.3 49.0 23.2 36.2 93.4 26.1 14.0 19.4 33.0 24.3 34.8 47.9 48.0 96.0 60.0 53.7 55.3 22.3 71.2 212.1 64.6 92.6 40.9 12.7 9.8 15.1 84.9 16.2 85.4 2.7 16.5 26.9 15.0 17.3 11.9 19.5 13.5 10.7 14.5 20.8 10.1 8.1 23.6 9.6 17.9 17.4 11.9 12.6 39.0 31.4 2.8 45.9 39.3 12.3 5.4 18.1 10.5 2.8 29.1 20.6 30.4 16.0 20.5 34.0 25.2 66.4 53.8 30.6 9.1 34.9 30.2 21.0 27.9 22.8 22.9 12.9 8.4 23.1 23.7 27.2 7.9 53.0 69.9 25.9 47.7 36.6 63.3 4.4 77.9 55.7 52.3 40.1 23.4 29.4 12.6 35.7 27.8 17.5 27.2 74.0 93.4 35.0 20.3 22.4 54.4 213.4 29.8 23.9 10.6 37.5 47.5 38.7 21.6 81.4 13.2 84.4 25.0 26.4 8.9 72.9 25.8 20.4 28.3 29.5 72.3 28.8 51.0 13.7 30.3 13.2 71.7 55.1 20.7 29.8 20.6 52.3 DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 452.8;Excitatory neurons: 1275.8;Inhibitory neurons: 719.8;Oligodendrocyte precursor cells: 1161.6;Oligodendrocytes: 610.2;Rod photoreceptor cells: 375.9" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 7 "B-cells: 1.1;granulocytes: 4.3" "Cell line enhanced" "Detected in many" "AF22: 27.9;Hep G2: 30.3;RH-30: 25.0;SuSa: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" 16.3 14.7 11.8 5.3 12.5 0.6 16.8 0.2 14.2 7.1 7.1 38.0 5.4 18.1 11.2 9.1 16.8 21.5 37.8 15.5 0.5 5.4 50.0 7.2 4.7 1.1 0.6 13.9 52.9 4.3 4.4 15.1 0.4 13.4 8.4 80.0 30.2 30.7 73.4 11.5 9.4 22.0 0.0 2.3 15.5 8.3 4.8 3.3 7.3 67.4 6.4 21.1 7.2 9.9 0.3 0.2 27.9 0.3 0.3 0.3 7.6 6.1 0.6 2.8 3.1 13.3 0.6 0.4 0.2 12.5 2.3 8.5 10.5 15.0 4.2 7.4 8.6 3.3 10.5 30.3 14.7 1.2 3.7 3.3 9.5 4.6 17.1 15.3 6.1 2.0 2.9 0.4 8.3 0.5 4.4 0.6 13.3 0.1 9.8 0.3 25.0 0.1 0.3 3.3 0.5 8.5 0.1 2.3 2.8 27.7 2.2 0.1 1.6 0.3 0.5 1.1 4.6 0.4 23.8 0.6 1.0 2.3 14.4 0.8 0.1 2.0 0.1 0.1 0.1 1.1 0.1 0.1 0.3 0.9 0.1 0.1 4.3 0.1 0.1 0.4 0.2 0.1 11.8 12.5 0.2 14.2 15.5 0.5 1.1 0.6 0.4 0.0 4.8 9.9 8.5 28.9 25.3 164.9 6.7 20.1 7.0 6.3 3.4 78.0 26.5 50.0 452.8 7.2 15.0 3.7 308.6 33.7 0.7 0.8 3.9 3.8 22.4 22.5 1.4 9.9 8.4 0.0 1275.8 12.3 9.5 26.1 3.6 5.6 1.3 37.9 6.1 49.8 4.2 11.8 719.8 1.3 6.1 4.8 5.4 20.5 89.2 3.5 19.6 94.6 6.7 54.9 0.0 1161.6 610.2 6.0 0.1 118.8 0.2 3.6 3.6 2.1 60.4 375.9 118.3 95.2 50.3 4.0 8.8 1.8 11.5 5.1 1.0 33.1 4.2 4.8 DMTN "DMT, EPB49" ENSG00000158856 "Dematin actin binding protein" Q08495 8 22048995-22082527 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 192.5" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 3.8;memory CD8 T-cell: 1.6;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.5;neutrophil: 1.2;T-reg: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;T-cells: 3.8" "Cell line enhanced" "Detected in many" "A549: 68.9;HEL: 225.9;Hep G2: 63.9;HMC-1: 65.6;OE19: 67.3;RPTEC TERT1: 87.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024290, HPA058487" Uncertain NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA024290: AB_1847601, HPA058487: " "unprognostic (6.74e-2)" "unprognostic (1.51e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (7.92e-5)" "unprognostic (2.88e-1)" "unprognostic (3.85e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-2)" "unprognostic (2.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.97e-1)" "prognostic favorable (3.85e-9)" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "unprognostic (8.07e-2)" 35.7 29.8 104.2 6.1 134.6 136.6 21.8 0.0 192.5 13.5 0.0 33.1 9.2 15.3 14.4 18.9 30.4 13.5 71.5 142.1 36.9 67.5 28.2 20.1 3.4 27.0 14.0 3.4 29.6 54.9 109.6 7.4 27.1 25.0 15.2 23.0 22.9 20.4 66.4 24.3 14.0 14.0 0.0 19.3 23.8 11.7 32.4 3.0 39.1 41.4 3.7 12.9 12.4 90.5 44.1 68.9 0.5 1.4 1.1 0.3 5.4 4.6 4.3 14.5 4.3 29.9 26.7 0.4 43.8 0.8 0.9 14.8 2.1 2.7 6.5 0.4 13.0 225.9 5.3 63.9 1.3 0.1 65.6 0.7 29.3 0.2 0.3 8.5 14.7 2.0 21.7 2.2 0.1 18.9 5.7 0.5 1.8 67.3 6.1 0.0 0.6 3.1 87.2 12.3 15.6 21.8 7.3 0.9 3.2 3.5 11.2 2.2 26.1 0.0 22.0 0.3 24.0 0.1 0.2 0.7 0.3 0.2 15.4 0.0 0.1 0.2 1.7 0.0 1.7 0.0 3.8 1.6 0.1 0.0 1.5 1.5 1.2 0.0 0.0 0.3 3.3 9.3 104.2 134.6 0.0 192.5 142.1 36.9 27.0 14.0 27.1 0.0 32.4 90.5 9.3 3.2 10.7 10.7 1.5 2.3 4.0 3.9 1.2 34.6 9.9 5.7 37.8 0.0 5.1 7.3 12.5 0.1 2.7 15.3 19.6 11.4 12.7 11.2 1.7 10.2 20.5 248.6 45.7 11.4 1.7 2.4 7.7 12.7 0.0 4.1 3.9 15.8 0.5 28.6 29.7 8.7 0.0 1.0 1.6 7.7 0.3 44.5 14.2 5.6 1.3 2.6 0.0 1.5 4.3 18.2 10.0 2.6 1.4 3.7 1.8 29.6 9.3 7.3 0.0 1.4 5.7 1.4 2.4 3.8 5.7 0.1 6.4 0.3 13.3 4.8 DNAAF1 "CILD13, DAU1, FLJ25330, LRRC50, ODA7, swt" ENSG00000154099 "Dynein axonemal assembly factor 1" Q8NEP3 16 84145287-84178767 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 22.7;testis: 45.3" "Cell type enhanced" "Detected in many" "Early spermatids: 116.2;Endometrial ciliated cells: 311.3;Plasma cells: 225.4;Respiratory ciliated cells: 494.5;Spermatocytes: 116.2" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 3.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Group enriched" "Detected in many" 4 "granulocytes: 2.3;T-cells: 1.0" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;Karpas-707: 4.9;PC-3: 1.4;SK-BR-3: 1.4;U-266/70: 4.0;U-266/84: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041166, HPA074239" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "Nuclear speckles" "HPA041166: AB_10794190, HPA074239: AB_2732250" "unprognostic (5.25e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-2)" "prognostic favorable (2.14e-4)" "unprognostic (1.42e-1)" "unprognostic (9.99e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (7.71e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-5)" "unprognostic (2.70e-2)" "unprognostic (4.61e-3)" "unprognostic (1.77e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-4)" "unprognostic (7.51e-4)" 0.3 0.7 1.4 0.1 1.2 1.2 0.3 1.1 1.9 2.2 9.7 0.3 0.0 0.5 1.4 0.4 22.7 0.0 0.4 1.6 1.5 1.0 0.8 3.5 0.0 4.1 7.3 0.4 0.3 0.3 2.4 0.2 4.3 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.0 3.0 0.7 0.2 45.3 1.6 0.0 1.6 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 4.0 2.8 0.4 0.1 0.0 0.0 1.3 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.3 0.3 0.1 0.4 1.0 0.3 1.4 1.2 1.1 1.9 1.6 1.5 4.1 7.3 4.3 3.0 1.6 1.3 1.1 0.0 12.4 1.6 5.7 0.6 1.5 9.6 0.0 1.4 4.5 1.5 0.7 1.5 67.2 3.7 54.2 0.2 0.5 0.1 0.0 1.3 116.2 311.3 4.4 1.9 0.0 0.0 9.6 0.4 0.4 2.4 0.5 14.6 3.8 2.6 2.2 0.6 1.9 0.0 5.2 0.0 18.3 7.0 1.5 26.7 1.2 21.6 87.2 0.0 0.8 2.4 1.0 0.5 0.6 0.9 0.0 0.4 225.4 1.4 0.0 1.7 494.5 51.0 0.0 1.6 7.3 116.2 17.0 0.2 0.3 0.4 4.5 1.2 0.3 0.9 DNAAF3 "C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22" ENSG00000167646 "Dynein axonemal assembly factor 3" Q8N9W5 19 55158661-55166722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 40.8;testis: 65.4" "Group enriched" "Detected in many" 5 "Early spermatids: 395.2;Late spermatids: 722.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 26.2;HEL: 31.6;K-562: 25.3;U-937: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056220 Approved "Nuclear bodies,Mitochondria" No No "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Nuclear bodies" "HPA056220: AB_2683071" "unprognostic (1.71e-2)" "unprognostic (2.67e-2)" "unprognostic (6.10e-2)" "unprognostic (9.93e-3)" "unprognostic (1.77e-1)" "unprognostic (1.87e-1)" "unprognostic (2.22e-2)" "unprognostic (1.82e-1)" "unprognostic (5.36e-2)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (8.03e-2)" 0.4 1.8 1.5 0.0 1.2 0.0 0.6 0.9 0.7 2.5 6.1 0.3 0.1 0.9 3.4 0.6 40.8 0.6 5.0 1.5 2.3 2.7 0.6 4.3 0.1 4.0 8.2 0.2 1.6 3.5 0.7 0.1 4.7 0.3 0.1 0.4 0.4 0.9 0.1 0.9 0.3 0.2 3.1 0.3 0.3 65.4 1.5 0.5 2.3 0.0 0.1 0.1 0.4 2.1 8.8 6.6 0.6 6.7 0.1 0.0 0.6 0.1 0.2 1.0 0.7 0.3 4.0 10.5 2.5 0.3 1.9 10.1 1.5 3.0 0.4 0.0 26.2 31.6 0.5 0.5 0.2 13.6 3.1 0.2 4.0 1.7 2.2 0.9 0.5 4.7 25.3 13.9 0.4 5.9 0.4 0.3 0.5 9.5 15.0 16.5 1.0 3.2 5.4 0.2 0.8 2.6 1.1 1.1 1.6 0.2 8.3 0.4 1.0 0.8 3.9 4.0 0.2 0.4 2.5 0.6 4.9 18.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.2 0.9 0.7 1.5 2.3 4.0 8.2 4.7 3.1 1.5 2.1 0.2 0.0 0.5 0.0 0.0 3.2 0.0 4.7 4.6 0.0 1.1 0.6 3.0 1.5 7.5 7.3 0.0 0.0 0.0 0.3 7.9 2.7 395.2 55.8 0.5 0.6 0.0 0.0 0.5 1.0 0.1 1.2 0.0 1.3 0.0 1.9 0.7 0.4 0.2 0.0 0.5 0.5 12.2 0.0 0.4 722.0 4.4 4.2 0.0 0.0 0.0 2.1 0.0 0.5 0.1 0.2 0.1 3.0 0.0 0.1 0.0 5.1 75.2 0.0 0.0 0.0 2.3 104.8 18.6 0.3 1.3 0.0 0.1 1.1 0.4 0.2 DNAH5 "CILD3, Dnahc5, HL1, KTGNR, PCD" ENSG00000039139 "Dynein axonemal heavy chain 5" Q8TE73 5 13690328-14011818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 14.0" "Cell type enhanced" "Detected in many" "Club cells: 61.7;Endometrial ciliated cells: 190.3;Respiratory ciliated cells: 258.7" "Cancer enhanced" "Detected in many" "prostate cancer: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;LHCN-M2: 1.1;PC-3: 2.7;RPTEC TERT1: 1.3;TIME: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA037469, HPA037470" Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA037469: AB_10672791, HPA037470: AB_10672348" "unprognostic (3.85e-1)" "unprognostic (8.17e-2)" "unprognostic (5.94e-2)" "unprognostic (1.12e-1)" "unprognostic (4.58e-3)" "unprognostic (6.23e-2)" "unprognostic (3.33e-3)" "unprognostic (2.86e-2)" "unprognostic (9.94e-2)" "unprognostic (4.39e-2)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (9.97e-3)" "unprognostic (8.87e-2)" "unprognostic (8.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.65e-1)" 0.0 0.1 0.9 0.0 1.1 0.0 1.5 0.5 0.3 0.3 14.0 0.1 0.0 0.1 0.1 0.0 3.8 0.1 0.0 1.0 1.7 0.8 1.0 1.7 0.0 4.2 6.7 0.0 0.9 0.0 2.0 0.0 4.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 0.3 1.8 0.0 1.1 0.0 0.0 0.8 0.0 1.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.1 0.0 0.5 0.0 0.5 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.3 0.4 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.5 0.3 1.0 1.7 4.2 6.7 4.0 2.1 1.8 1.4 0.3 3.2 24.4 7.2 0.2 0.0 1.7 5.6 0.0 0.0 11.7 7.0 1.5 14.3 61.7 5.5 0.0 0.0 0.1 0.0 0.0 6.7 7.3 190.3 1.9 1.2 1.8 0.0 12.9 3.6 0.2 1.8 0.0 12.4 2.5 0.0 0.0 10.9 0.0 0.0 7.8 0.0 6.1 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 4.0 0.4 2.6 0.0 0.0 0.1 14.8 0.0 4.3 258.7 0.0 0.0 1.6 2.6 2.6 3.6 0.0 0.0 0.0 0.4 0.1 0.0 3.8 DNAH9 "DNAH17L, Dnahc9, DNAL1, DYH9, HL-20, HL20, KIAA0357" ENSG00000007174 "Dynein axonemal heavy chain 9" Q9NYC9 17 11598470-11969748 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 28.2;choroid plexus: 27.6;fallopian tube: 35.4" "Cell type enhanced" "Detected in many" "Early spermatids: 48.7;Endometrial ciliated cells: 97.5;Excitatory neurons: 26.8;Late spermatids: 56.5;Respiratory ciliated cells: 110.5" "Group enriched" "Detected in some" 4 "endometrial cancer: 1.1;glioma: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 3.1;WM-115: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052641 Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA052641: AB_2681895" "unprognostic (4.16e-3)" "unprognostic (3.67e-2)" "unprognostic (9.31e-2)" "prognostic favorable (6.79e-5)" "unprognostic (8.37e-3)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-1)" "unprognostic (7.35e-2)" "unprognostic (1.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.93e-1)" "unprognostic (1.14e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-3)" "unprognostic (5.31e-2)" 2.1 0.8 9.7 0.3 8.1 0.0 1.5 9.2 8.0 1.7 27.6 0.2 0.0 1.4 2.2 0.1 35.4 0.4 0.2 12.1 10.4 1.7 0.1 2.8 0.0 24.0 28.2 1.4 1.8 3.6 3.2 0.3 18.1 0.8 0.0 6.6 0.3 2.0 0.2 0.3 0.1 0.5 19.5 0.1 0.3 6.3 12.1 0.1 0.9 0.0 0.0 0.3 0.3 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 8.1 9.2 8.0 12.1 10.4 24.0 28.2 18.1 19.5 12.1 11.6 0.1 3.2 1.1 8.5 0.0 0.8 0.9 3.6 1.2 2.0 0.2 0.4 1.7 0.0 6.1 3.7 2.1 0.0 0.0 0.6 1.9 1.4 48.7 97.5 2.0 0.3 0.0 0.0 26.8 0.2 0.0 1.5 0.0 2.1 1.3 1.2 0.0 0.0 0.1 0.0 17.6 0.2 2.0 0.0 0.4 56.5 0.6 0.2 0.0 3.7 0.0 1.8 0.0 11.1 8.3 0.1 0.0 3.0 0.1 0.6 0.0 0.2 110.5 8.2 0.0 1.5 2.5 5.3 2.4 0.6 1.1 0.1 0.3 1.4 0.0 0.6 DNAI1 "CILD1, DIC1, PCD" ENSG00000122735 "Dynein axonemal intermediate chain 1" Q9UI46 9 34457414-34520988 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.9;choroid plexus: 28.3;fallopian tube: 33.9;pituitary gland: 9.5;testis: 33.5" "Cell type enhanced" "Detected in some" "Early spermatids: 29.6;Endometrial ciliated cells: 48.8;Late spermatids: 35.0;Respiratory ciliated cells: 132.2;Spermatocytes: 56.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;HDLM-2: 1.4;SK-BR-3: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021649, HPA021843" Enhanced NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA021649: AB_1847913, HPA021843: AB_1847914" "unprognostic (9.61e-2)" "unprognostic (5.16e-2)" "unprognostic (4.59e-2)" "unprognostic (1.44e-3)" "unprognostic (3.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (6.39e-2)" "unprognostic (4.38e-1)" "unprognostic (1.51e-1)" "unprognostic (8.16e-3)" "unprognostic (8.14e-2)" "unprognostic (2.74e-2)" "unprognostic (3.77e-2)" "unprognostic (2.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" 0.0 0.0 2.7 0.0 3.2 0.0 0.5 2.3 2.5 2.2 28.3 0.0 0.0 0.9 0.2 0.0 33.9 0.1 0.1 2.8 3.1 1.3 0.1 4.5 0.0 7.3 9.9 0.1 0.9 1.2 9.5 0.0 4.8 0.2 0.0 2.7 0.0 0.1 0.1 0.0 0.0 0.0 5.5 0.0 0.2 33.5 3.2 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.6 0.2 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 1.0 0.2 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.2 2.3 2.5 2.8 3.1 7.3 9.9 4.8 5.5 3.2 2.4 0.0 0.0 0.5 3.9 0.1 0.0 0.0 5.0 0.0 0.0 0.5 0.3 0.4 0.0 11.0 0.0 4.2 0.2 0.0 0.0 1.9 0.0 29.6 48.8 0.5 0.2 0.0 0.0 9.4 0.0 0.1 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.0 2.0 0.0 0.0 35.0 0.3 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.0 0.4 132.2 1.3 0.0 0.0 1.4 56.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DNAJB12 "DJ10, FLJ20027" ENSG00000148719 "DnaJ heat shock protein family (Hsp40) member B12" Q9NXW2 10 72332830-72355149 "Predicted membrane proteins, Transporters" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 235.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010642, HPA072702" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "Nuclear membrane" "HPA010642: AB_1078692, HPA072702: " "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (4.79e-4)" "unprognostic (6.01e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.73e-2)" "unprognostic (5.60e-2)" "unprognostic (8.85e-3)" "unprognostic (1.95e-1)" "unprognostic (1.32e-1)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (4.73e-1)" "unprognostic (1.16e-2)" "unprognostic (1.87e-1)" 24.1 29.8 18.3 18.1 19.5 27.6 24.5 20.0 20.4 21.6 19.5 23.3 21.4 24.0 23.4 23.2 20.8 17.5 26.8 19.0 18.1 23.9 28.0 21.1 16.4 20.0 18.8 22.6 26.9 32.9 23.7 20.3 19.1 23.4 14.7 16.6 28.4 17.7 37.5 28.5 20.7 19.0 18.4 24.8 23.9 21.4 18.9 17.3 23.5 23.5 16.0 21.6 20.6 20.0 37.4 38.3 23.4 39.3 30.5 31.1 29.6 36.6 63.8 49.5 45.9 44.7 64.3 27.2 28.8 45.1 31.3 61.4 22.2 33.0 26.9 29.9 29.4 14.7 23.0 29.6 68.5 30.1 54.2 39.6 67.6 44.1 55.8 45.0 35.1 25.6 23.2 40.2 43.3 36.7 26.0 26.3 10.8 29.1 11.1 23.4 17.8 18.9 37.7 21.7 16.1 23.0 20.0 74.0 36.8 12.9 28.2 34.2 39.1 24.6 33.4 28.0 46.7 33.8 27.3 16.0 40.6 32.6 17.1 18.7 29.2 18.7 12.8 31.5 11.4 11.5 12.5 9.6 24.6 11.1 10.3 10.2 36.6 13.9 28.9 16.4 13.8 17.5 18.3 19.5 20.0 20.4 19.0 18.1 20.0 18.8 19.1 18.4 18.9 20.0 30.3 28.9 29.3 10.1 30.1 13.4 30.6 38.6 25.6 33.3 36.1 29.6 23.3 50.1 44.3 23.9 22.9 41.1 37.7 38.1 11.7 34.2 122.2 25.1 26.1 25.3 29.4 31.2 12.7 64.3 41.1 28.6 23.4 29.3 40.0 26.4 21.0 29.6 38.1 30.3 13.0 28.8 12.2 36.0 16.0 235.7 36.4 37.6 10.6 7.5 39.6 33.6 35.0 12.1 15.2 34.9 38.1 35.0 34.2 27.4 62.2 34.4 26.8 35.6 52.6 27.4 34.4 32.4 10.9 28.1 15.5 68.0 22.8 37.0 25.9 35.2 DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 319.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.4;Cone photoreceptor cells: 89.6;Excitatory neurons: 176.1;Inhibitory neurons: 182.2;Rod photoreceptor cells: 78.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 319.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 126.9;U-87 MG: 46.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910" Enhanced NA NA 8800 "Cluster 10: Brain - Neuronal signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB005920: , HPA049910: AB_2680948" "unprognostic (3.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-3)" "unprognostic (3.95e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (6.53e-2)" "unprognostic (6.62e-3)" "unprognostic (6.30e-1)" "unprognostic (9.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (3.07e-3)" "unprognostic (1.10e-3)" 22.2 7.9 99.8 3.7 129.1 2.0 13.2 13.6 319.5 30.8 0.0 8.0 1.9 8.8 2.4 5.5 9.4 13.4 7.8 140.1 15.9 14.1 5.3 4.6 2.4 50.7 4.1 2.5 8.4 4.1 33.6 2.5 36.6 9.0 2.7 68.3 9.0 3.0 3.2 15.0 9.0 5.3 0.0 1.0 5.0 4.9 10.0 0.9 5.2 4.0 1.8 10.6 21.6 123.1 8.7 126.9 11.3 2.8 3.6 36.8 0.6 8.0 18.9 15.7 6.5 1.7 2.6 0.2 10.7 16.7 0.6 15.3 1.8 0.8 8.6 0.1 12.1 8.3 19.5 0.5 2.6 1.1 5.6 9.8 0.2 12.4 0.2 15.2 0.0 7.3 3.1 0.5 0.0 3.6 0.7 2.7 12.2 2.2 23.1 15.6 0.4 3.9 2.4 0.0 16.1 27.1 27.1 0.8 1.2 1.4 0.3 11.2 0.6 0.5 34.8 36.2 16.6 1.0 0.4 0.8 46.8 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 99.8 129.1 13.6 319.5 140.1 15.9 50.7 4.1 36.6 0.0 10.0 123.1 2.2 0.0 0.0 18.9 0.9 7.9 1.7 0.3 8.0 112.4 2.9 3.9 2.0 5.7 0.8 0.0 89.6 0.3 0.2 0.4 1.9 0.8 0.9 1.3 19.0 1.8 0.0 0.0 176.1 0.9 0.4 24.3 2.6 1.4 1.3 2.8 0.7 0.6 10.6 50.5 182.2 0.9 0.0 0.6 10.5 1.0 2.8 9.2 3.6 22.5 1.3 10.7 0.0 33.7 14.3 0.6 5.0 1.5 0.7 0.8 2.5 5.3 1.1 78.4 0.0 2.1 3.8 1.0 1.8 2.5 7.5 0.8 1.6 2.1 1.6 0.8 DOC2B DOC2BL ENSG00000272636 "Double C2 domain beta" Q14184 17 142789-181650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;retina: 24.6" "Group enriched" "Detected in many" 5 "Adipocytes: 49.4;Cone photoreceptor cells: 175.2;Muller glia cells: 146.7;Rod photoreceptor cells: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 37.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 56.1" HPA043168 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA043168: AB_2678349" "prognostic favorable (3.45e-4)" "unprognostic (2.28e-3)" "unprognostic (3.17e-1)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "prognostic favorable (8.68e-4)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (2.62e-1)" "unprognostic (8.78e-3)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (2.27e-3)" "unprognostic (2.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-3)" "unprognostic (4.87e-3)" 15.9 4.5 11.6 3.0 12.7 6.2 13.9 18.6 21.1 3.7 1.3 4.0 0.0 4.0 0.0 14.4 5.8 0.0 5.3 22.5 6.5 8.7 0.7 3.4 1.3 8.7 11.7 1.1 10.0 0.2 6.7 1.4 10.8 3.6 1.1 24.6 2.1 0.6 2.7 4.4 4.5 1.5 12.6 3.3 3.4 0.3 12.2 0.8 3.0 0.1 2.5 4.4 5.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 12.7 18.6 21.1 22.5 6.5 8.7 11.7 10.8 12.6 12.2 0.9 49.4 0.0 2.3 0.3 0.2 0.0 0.8 0.0 2.2 10.1 1.5 1.3 2.0 0.0 0.0 9.2 175.2 0.0 0.0 0.2 0.0 0.2 1.1 0.7 4.6 22.8 0.0 0.0 3.8 4.2 0.0 2.3 9.2 0.8 0.0 0.1 18.5 0.2 0.1 1.7 2.3 0.0 0.0 0.3 0.0 2.5 0.0 0.5 0.0 1.0 0.6 146.7 0.0 1.5 0.1 4.3 0.0 0.0 0.0 0.9 0.0 0.5 1.5 100.7 0.0 2.3 0.8 0.2 0.1 1.8 0.0 0.3 0.1 0.8 0.2 3.6 DOCK11 "ACG, FLJ32122, FLJ43653, ZIZ2" ENSG00000147251 "Dedicator of cytokinesis 11" Q5JSL3 X 118495815-118686163 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 54.3" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 100.4;Kupffer cells: 47.5;Macrophages: 45.7;Microglial cells: 67.5;NK-cells: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 63.3;HMC-1: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059695 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA059695: AB_2684104" "unprognostic (4.09e-1)" "unprognostic (1.47e-1)" "unprognostic (1.68e-1)" "unprognostic (2.56e-1)" "unprognostic (1.32e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.50e-1)" "unprognostic (5.56e-2)" "unprognostic (1.76e-1)" "unprognostic (6.37e-3)" "unprognostic (3.06e-1)" "unprognostic (2.66e-1)" "unprognostic (3.49e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (8.11e-2)" "unprognostic (8.16e-3)" 54.3 8.2 5.7 15.4 11.2 33.6 34.9 4.1 6.8 17.1 4.7 26.0 3.1 12.6 9.7 6.1 13.7 8.5 6.9 5.6 9.9 10.8 3.5 25.8 23.7 6.3 6.8 4.2 2.3 4.4 28.3 12.8 7.1 6.7 5.7 1.2 7.0 3.1 3.8 8.2 19.9 8.9 5.8 34.1 12.3 2.6 5.6 21.0 18.3 4.8 17.8 16.6 14.3 7.7 0.1 5.9 4.8 4.5 63.3 26.8 12.7 6.7 14.5 5.5 14.2 0.7 0.1 18.2 0.6 24.3 6.5 0.2 8.5 0.0 4.8 22.7 7.4 39.8 6.2 0.2 20.4 24.3 92.3 18.9 0.4 5.8 6.4 3.8 0.2 15.6 12.3 32.0 3.5 4.1 14.6 32.2 5.0 5.3 9.2 9.7 12.3 0.6 0.1 1.3 1.7 11.3 20.3 18.7 6.6 3.7 2.2 20.3 0.3 4.4 1.4 25.5 3.0 9.8 15.7 16.6 9.5 38.1 2.3 5.7 3.3 6.2 6.4 4.9 4.1 3.7 5.4 5.2 3.6 3.8 4.8 6.1 10.1 5.9 6.2 2.8 9.1 1.8 5.7 11.2 4.1 6.8 5.6 9.9 6.3 6.8 7.1 5.8 5.6 7.7 10.9 28.9 3.7 6.8 38.3 2.9 0.1 0.4 0.6 0.5 0.7 0.9 2.7 0.0 7.7 7.3 0.0 3.0 34.5 0.3 0.0 0.2 0.5 0.4 5.4 7.4 4.2 14.7 4.4 0.0 3.2 18.7 5.1 0.3 44.4 0.2 2.9 1.1 20.6 0.0 100.4 3.2 2.0 47.5 24.9 0.6 12.2 45.7 8.8 67.5 38.6 0.3 52.5 20.6 14.8 0.7 1.5 4.9 22.7 0.4 3.0 6.3 1.2 0.4 26.3 4.3 14.0 3.8 3.3 0.6 1.8 6.8 36.6 0.2 1.3 0.4 DOCK6 "KIAA1395, ZIR1" ENSG00000130158 "Dedicator of cytokinesis 6" Q96HP0 19 11199295-11262524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.3;Cardiomyocytes: 185.4;Endothelial cells: 64.8;Hepatic stellate cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 68.2;TIME: 68.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049423, HPA049424" Approved Supported Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA049423: AB_2680760, HPA049424: AB_2680761" "unprognostic (2.69e-2)" "unprognostic (2.27e-1)" "unprognostic (9.51e-2)" "unprognostic (3.35e-2)" "unprognostic (4.72e-3)" "prognostic favorable (9.09e-4)" "unprognostic (2.54e-2)" "unprognostic (4.91e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (2.57e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (5.41e-2)" "unprognostic (2.95e-1)" 31.2 9.9 7.4 5.4 6.3 0.4 27.5 4.5 9.7 15.4 3.6 16.8 14.2 14.7 4.6 16.8 11.6 12.0 29.6 4.6 5.1 26.3 13.2 46.3 4.9 7.8 7.1 12.0 14.4 5.4 11.9 15.0 6.9 14.8 6.2 1.8 11.4 7.5 15.1 25.2 15.4 7.1 5.7 14.5 15.8 5.8 11.4 2.1 29.0 9.3 2.6 14.2 16.6 5.6 14.6 8.9 9.9 8.1 7.3 10.5 15.9 4.2 6.9 4.1 6.3 16.9 11.2 0.9 25.4 7.1 3.9 8.3 4.3 22.3 2.5 12.4 7.0 2.8 2.2 12.8 11.8 4.3 13.7 8.1 13.0 7.5 17.0 7.9 68.2 0.3 15.7 0.0 9.1 32.7 0.1 14.7 12.5 13.2 16.6 0.9 6.7 14.0 6.8 20.0 0.6 17.6 4.2 4.2 7.6 6.5 4.9 7.6 68.8 7.5 7.8 17.1 7.6 1.2 0.2 14.1 6.3 3.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 6.3 4.5 9.7 4.6 5.1 7.8 7.1 6.9 5.7 11.4 5.6 70.3 3.2 12.6 6.8 0.9 6.5 6.2 8.5 4.6 1.4 4.3 3.8 185.4 5.7 11.3 25.8 0.0 0.3 0.9 15.6 1.9 5.4 3.5 3.9 8.9 64.8 12.1 0.0 2.9 6.8 1.3 19.6 35.2 7.2 5.1 4.7 55.3 5.6 4.6 0.0 5.9 15.9 8.2 2.5 4.4 1.3 22.4 1.6 3.6 35.6 0.0 4.6 0.0 7.1 3.5 11.9 10.9 9.4 1.9 8.4 11.9 1.9 9.2 2.6 19.7 8.4 30.8 1.5 4.3 7.4 11.5 0.5 1.2 7.8 9.7 9.0 DOCK9 "KIAA1058, ZIZ1" ENSG00000088387 "Dedicator of cytokinesis 9" Q9BZ29 13 98793429-99086625 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 216.7" "Cell type enhanced" "Detected in many" "Adipocytes: 158.7;Excitatory neurons: 150.6;Inhibitory neurons: 202.2;Microglial cells: 148.0;Oligodendrocyte precursor cells: 238.8;Oligodendrocytes: 402.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 2.0;MAIT T-cell: 4.8;memory CD4 T-cell: 5.2;memory CD8 T-cell: 2.1;naive CD4 T-cell: 6.0;naive CD8 T-cell: 4.0;NK-cell: 7.3;T-reg: 2.4" "Group enriched" "Detected in many" 11 "NK-cells: 7.3;T-cells: 6.0" "Cell line enhanced" "Detected in many" "BEWO: 200.8;hTERT-HME1: 435.4;HUVEC TERT2: 180.9;TIME: 179.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034061, CAB034065, HPA043940" Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB034061: AB_2277513, CAB034065: AB_2094798, HPA043940: AB_2678741" "unprognostic (5.31e-2)" "unprognostic (3.20e-2)" "unprognostic (8.76e-2)" "unprognostic (4.24e-2)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.62e-2)" "unprognostic (2.96e-1)" "unprognostic (2.47e-1)" "unprognostic (1.16e-1)" "unprognostic (6.38e-3)" "unprognostic (2.79e-1)" "unprognostic (7.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.36e-2)" "unprognostic (3.31e-2)" 83.2 22.4 82.6 21.4 137.2 6.0 71.1 96.6 91.0 42.9 30.8 44.4 15.7 31.3 35.5 93.1 30.3 36.6 58.9 72.8 93.8 21.9 15.8 93.0 33.8 116.6 112.1 27.4 19.9 41.8 21.1 98.2 123.4 23.0 20.8 39.5 51.2 21.7 25.9 76.9 35.2 36.9 86.6 16.8 24.7 16.2 110.4 47.8 62.6 64.3 40.4 29.0 49.6 216.7 61.6 19.4 10.6 14.2 10.6 8.3 200.8 17.2 14.2 12.1 10.7 127.4 47.7 51.3 39.8 16.6 21.8 59.5 27.4 54.3 21.8 52.2 15.2 0.0 37.6 2.1 14.0 0.1 2.9 9.0 37.2 12.4 435.4 27.9 180.9 33.0 10.6 11.6 52.1 20.2 35.5 0.3 4.9 84.6 14.2 2.1 39.3 2.7 38.3 50.8 22.4 24.3 26.4 63.4 15.7 85.9 16.9 0.4 179.7 9.7 11.4 6.5 28.5 17.6 14.8 8.6 15.6 0.0 16.0 0.0 0.0 0.0 2.0 0.0 4.8 0.6 5.2 2.1 0.0 0.2 6.0 4.0 0.1 7.3 0.0 0.0 2.4 1.5 82.6 137.2 96.6 91.0 72.8 93.8 116.6 112.1 123.4 86.6 110.4 216.7 158.7 16.0 39.5 37.5 3.4 15.3 7.1 14.7 10.2 37.9 15.4 6.5 9.4 11.5 12.5 9.2 50.1 35.6 7.0 11.9 1.9 5.4 1.7 10.5 5.3 90.2 6.7 3.6 150.6 6.6 8.3 17.2 2.6 21.4 2.5 18.0 47.8 8.4 5.0 25.2 202.2 6.0 10.2 1.9 7.4 3.3 7.8 1.7 1.8 148.0 0.4 12.9 4.1 238.8 402.2 14.7 5.6 14.7 2.8 10.1 10.6 3.8 7.1 23.9 0.0 122.6 12.4 7.2 5.4 25.6 32.0 17.2 11.0 2.4 5.9 10.5 DOK1 p62dok ENSG00000115325 "Docking protein 1" Q99704 2 74549026-74557551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 36.8;Hofbauer cells: 48.6;Macrophages: 31.2;monocytes: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004224, HPA048561" Approved Supported Cytosol NA NA 80000 "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB004224: AB_627447, HPA048561: AB_2680443" "unprognostic (2.40e-2)" "unprognostic (2.07e-2)" "unprognostic (2.60e-1)" "prognostic favorable (8.42e-4)" "unprognostic (9.86e-3)" "unprognostic (1.28e-1)" "unprognostic (7.10e-2)" "prognostic favorable (4.64e-4)" "unprognostic (7.57e-2)" "unprognostic (1.85e-2)" "unprognostic (1.89e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (3.16e-6)" "unprognostic (8.65e-2)" "unprognostic (2.40e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-2)" 10.8 3.7 8.8 10.2 8.3 13.7 4.7 8.2 9.0 6.6 7.6 5.2 4.4 4.9 0.7 1.4 6.3 3.2 2.8 7.8 8.7 2.7 1.5 6.6 12.3 10.7 8.7 4.2 3.7 6.3 2.2 4.0 9.2 3.1 3.8 0.9 3.0 4.0 1.1 1.6 5.8 4.8 9.2 11.6 6.7 1.7 9.4 7.6 3.9 1.7 10.1 4.7 2.7 9.0 5.3 2.0 6.0 3.0 13.9 16.8 4.2 12.8 10.0 5.2 8.5 1.6 6.1 3.3 18.0 12.3 11.3 0.7 6.1 2.8 1.9 76.3 5.7 43.1 4.4 0.3 10.0 22.0 41.0 12.5 0.0 28.5 14.7 21.7 6.2 13.8 12.7 9.5 10.5 5.6 15.8 45.7 11.1 10.8 1.6 13.0 12.9 3.5 2.7 4.5 2.0 10.0 2.5 0.7 6.7 1.7 3.3 24.1 11.7 32.7 15.1 15.3 2.9 12.6 9.6 0.1 32.9 35.3 5.5 39.0 52.3 38.9 17.3 51.4 13.9 22.9 14.1 15.4 51.3 26.3 10.3 10.3 52.9 27.4 59.3 10.8 24.3 39.8 8.8 8.3 8.2 9.0 7.8 8.7 10.7 8.7 9.2 9.2 9.4 9.0 6.7 9.6 8.8 2.9 15.0 2.0 1.1 3.7 1.2 0.5 2.2 2.8 1.8 4.3 2.0 5.5 0.0 1.9 13.6 8.7 0.0 11.9 0.3 7.4 5.8 7.2 3.0 12.4 0.1 9.1 4.2 6.5 6.1 5.6 36.8 5.8 9.7 0.6 48.6 1.7 0.5 5.9 2.0 26.3 24.2 1.0 5.0 31.2 3.6 4.7 41.1 9.8 16.5 0.5 0.6 10.2 10.0 6.0 6.3 2.4 8.1 3.9 1.7 0.5 6.6 4.1 8.3 0.5 2.1 0.3 1.6 2.3 13.5 7.0 6.8 1.6 DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "dendritic cells: 130.6;Hofbauer cells: 131.8;Kupffer cells: 171.8;Langerhans cells: 288.4;Macrophages: 181.5;NK-cells: 344.0;T-cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 25.3;HEL: 54.3;HMC-1: 119.8;JURKAT: 22.3;THP-1: 43.1;U-937: 42.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" 9.5 5.0 1.1 26.5 1.2 19.5 5.0 1.2 2.3 1.9 2.5 5.5 7.0 2.2 0.5 2.3 3.5 6.5 3.5 1.3 1.3 3.0 6.1 25.6 26.3 1.4 1.5 1.4 1.9 0.5 1.1 7.9 1.5 2.3 3.6 0.0 3.4 1.5 2.0 2.3 9.5 6.9 1.2 40.9 6.8 1.6 4.5 16.4 2.4 1.6 7.8 8.4 2.3 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 54.3 0.0 0.1 0.0 0.4 119.8 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.8 5.0 0.0 0.0 0.9 8.7 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.3 1.4 42.0 0.2 577.6 484.3 1565.6 398.3 624.0 184.5 14.5 274.3 304.8 421.9 6.6 151.0 185.9 37.2 307.6 580.7 7.6 597.2 810.3 1.1 1.2 1.2 2.3 1.3 1.3 1.4 1.5 1.5 1.2 4.5 1.5 2.0 3.2 18.1 0.0 13.2 11.5 0.6 0.0 0.0 0.0 1.2 1.8 2.1 0.0 1.3 3.7 0.0 0.7 130.6 0.3 0.0 0.1 0.2 0.2 0.5 2.8 0.0 10.5 0.1 0.0 1.0 2.6 3.1 0.4 36.3 0.1 5.7 1.1 131.8 0.0 0.0 0.2 0.0 171.8 288.4 0.6 0.3 181.5 19.6 0.0 74.8 0.0 344.0 0.0 0.0 0.0 0.0 0.0 15.4 0.2 0.0 0.7 1.5 0.0 0.0 0.6 2.5 0.2 4.3 0.7 8.5 1.0 147.4 0.0 0.2 0.8 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 DPH3 "DELGIP, DELGIP1, DESR1, DPH3A, KTI11, MGC20197, ZCSL2" ENSG00000154813 "Diphthamide biosynthesis 3" Q96FX2 3 16257061-16264969 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035287 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA035287: AB_10604113" "unprognostic (2.49e-2)" "unprognostic (8.80e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "unprognostic (1.52e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (1.22e-1)" "unprognostic (2.83e-1)" "unprognostic (5.06e-2)" "unprognostic (5.83e-2)" "unprognostic (4.13e-1)" "unprognostic (5.90e-3)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (1.19e-2)" "unprognostic (6.44e-2)" 14.2 11.9 12.7 9.6 13.5 8.4 10.3 14.3 14.3 10.2 13.6 11.5 10.7 10.0 11.0 9.4 8.9 10.2 13.9 12.2 15.6 13.1 15.3 11.1 8.9 15.4 14.4 6.1 7.8 9.0 8.5 13.2 15.0 9.3 8.7 13.4 5.7 11.1 29.4 4.9 13.3 15.2 14.7 9.1 9.4 8.5 13.6 11.5 12.4 20.1 8.1 12.4 5.8 15.5 10.5 14.6 31.9 18.9 58.9 39.7 24.8 29.9 24.4 28.0 31.3 18.1 5.8 10.0 9.3 37.5 24.0 6.2 29.4 17.7 32.6 50.5 20.4 16.6 11.5 21.0 36.7 24.5 15.6 28.6 23.6 36.0 15.2 17.6 25.5 17.4 26.9 16.4 39.9 14.1 19.0 16.5 25.6 15.9 14.7 12.9 20.7 15.4 24.9 8.0 7.2 20.2 13.8 6.7 35.4 25.6 12.5 23.9 29.9 22.9 15.0 41.7 24.0 12.6 44.5 12.8 33.6 27.2 20.7 27.1 16.7 25.7 11.3 22.8 14.0 10.1 11.9 13.8 15.9 9.9 9.9 11.9 35.5 10.7 21.6 6.2 11.9 12.7 12.7 13.5 14.3 14.3 12.2 15.6 15.4 14.4 15.0 14.7 13.6 15.5 32.3 19.2 22.4 10.1 31.0 51.6 42.9 41.0 29.0 11.6 32.9 34.7 34.9 25.8 32.4 16.5 12.5 47.9 28.1 43.0 41.1 49.5 109.1 27.5 35.3 32.5 17.9 32.0 12.0 57.2 80.6 34.4 30.1 33.3 52.0 11.2 26.7 41.6 101.6 6.7 10.3 22.6 26.4 45.5 61.7 63.3 20.5 46.4 28.4 3.7 71.5 24.8 29.9 6.6 9.2 66.6 32.4 15.8 42.2 42.6 79.1 45.4 33.9 15.1 13.1 33.4 36.7 80.4 40.1 31.3 52.4 80.9 34.5 18.7 19.0 47.1 DPH6 "ATPBD4, MGC14798" ENSG00000134146 "Diphthamine biosynthesis 6" Q7L8W6 15 35217345-35546193 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 91.7;Oligodendrocytes: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042976, HPA055496" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042976: AB_10964890, HPA055496: AB_2682835" "unprognostic (9.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (1.82e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (9.94e-2)" "unprognostic (1.76e-1)" "unprognostic (1.49e-3)" "unprognostic (7.92e-3)" "unprognostic (1.13e-1)" "unprognostic (4.65e-6)" "unprognostic (9.70e-2)" "unprognostic (5.61e-2)" "unprognostic (2.18e-2)" "unprognostic (7.44e-2)" 8.6 7.5 3.7 4.9 4.7 5.4 10.8 4.6 5.0 6.8 3.6 6.7 6.1 7.9 10.7 9.6 8.1 6.0 10.2 3.6 4.7 10.4 8.1 5.3 5.3 4.6 4.4 9.7 14.3 8.7 5.9 8.1 4.8 5.8 7.0 8.9 6.7 6.1 10.8 9.7 6.6 6.4 4.3 6.3 6.8 5.9 3.9 7.0 10.8 6.9 7.4 8.0 7.1 5.7 16.9 8.9 14.7 12.5 2.6 11.7 14.3 6.2 10.8 14.7 7.6 11.9 15.5 5.2 14.8 5.7 17.9 19.0 17.2 17.9 17.5 4.1 10.7 19.6 9.9 18.9 15.3 10.6 12.1 9.9 22.2 5.9 28.5 9.0 14.4 11.0 21.8 20.6 13.6 6.6 13.0 9.8 13.0 25.4 8.1 16.0 13.7 7.2 12.9 21.0 10.7 10.4 11.6 12.8 10.7 8.5 44.6 14.4 4.4 14.2 13.8 14.4 10.0 18.2 31.3 13.4 12.3 17.7 13.9 0.0 6.7 0.3 6.0 6.7 7.7 8.9 8.1 8.4 6.7 6.3 10.3 9.3 0.3 14.7 6.2 5.8 5.8 4.5 3.7 4.7 4.6 5.0 3.6 4.7 4.6 4.4 4.8 4.3 3.9 5.7 15.9 16.0 7.5 91.7 18.7 31.0 20.0 19.8 24.5 29.2 12.0 16.6 15.8 18.6 17.2 9.2 39.6 26.7 9.3 7.5 13.7 16.3 2.2 10.7 13.7 10.0 5.4 16.8 28.0 24.1 23.5 12.0 21.4 13.3 3.8 21.1 5.7 7.4 17.5 18.5 47.0 7.4 14.2 10.3 12.9 3.3 14.0 9.8 16.0 44.0 14.3 15.0 11.3 71.9 101.5 18.7 7.1 6.8 6.9 8.9 13.4 19.9 7.6 24.2 0.0 18.9 14.0 9.8 14.0 21.2 23.2 22.6 9.9 21.9 10.5 13.4 DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 228.8" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 166.5" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075379 Enhanced NA NA 27000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" 0.2 0.0 0.0 0.1 0.0 0.2 9.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 228.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 2.6 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 14.1 0.3 0.0 2.2 0.9 0.1 0.4 29.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.4 0.0 0.0 3.6 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.5 166.5 0.4 0.6 0.0 0.0 0.3 DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2368.6;Basal prostatic cells: 1651.4;Basal squamous epithelial cells: 3008.4;Cone photoreceptor cells: 1401.1;Oligodendrocytes: 1410.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 488.1;hTERT-HME1: 371.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Microtubules" Cytosol "HPA030200: AB_10601901" "unprognostic (4.87e-3)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (3.60e-2)" "unprognostic (5.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (7.62e-2)" 60.9 86.2 206.5 16.2 275.8 3.3 117.3 240.6 221.9 158.8 143.3 173.2 25.4 167.1 38.2 66.1 103.9 32.6 166.0 194.6 230.7 52.2 80.8 108.0 11.3 258.1 250.4 78.2 39.8 36.7 78.8 28.7 263.4 84.5 32.4 87.4 100.3 48.7 143.1 166.2 64.2 106.0 209.1 36.7 68.9 28.4 243.3 31.4 29.8 104.1 15.2 90.4 113.2 325.4 62.4 26.6 41.2 20.8 79.5 103.5 24.6 82.2 89.7 37.8 42.1 17.1 15.5 10.4 32.2 220.7 35.6 46.7 34.4 161.2 73.0 52.3 45.2 17.8 49.5 31.4 65.9 15.0 0.4 58.3 488.1 92.5 371.6 69.1 73.3 9.5 12.6 38.2 113.9 20.2 5.1 6.8 27.7 35.6 21.9 0.1 28.8 16.5 118.8 83.0 47.2 37.8 32.7 11.7 64.1 67.7 18.6 27.2 176.5 77.3 55.9 37.0 68.9 39.6 28.6 5.0 55.8 8.8 40.3 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 0.3 1.3 0.0 0.1 206.5 275.8 240.6 221.9 194.6 230.7 258.1 250.4 263.4 209.1 243.3 325.4 193.2 336.5 11.8 1048.7 5.6 2368.6 1651.4 250.1 3008.4 673.1 81.0 301.5 862.8 77.2 161.7 55.2 1401.1 61.5 7.8 357.8 7.9 204.3 53.6 133.8 218.4 122.7 44.9 12.4 550.4 66.3 11.6 212.5 71.9 166.8 17.1 478.7 60.7 80.3 21.8 307.9 591.7 100.3 118.0 74.2 124.6 15.5 133.3 56.6 215.3 215.5 46.6 200.8 2.1 630.3 1410.3 194.1 283.0 152.4 27.2 229.8 124.2 10.3 52.0 122.6 65.7 381.8 196.6 20.0 13.7 298.2 857.2 26.5 19.7 30.5 48.1 142.8 DTHD1 FLJ16686 ENSG00000197057 "Death domain containing 1" Q6ZMT9 4 36281616-36347511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.8;fallopian tube: 13.7;lung: 3.5;lymphoid tissue: 4.0" "Cell type enhanced" "Detected in some" "dendritic cells: 37.9;Early spermatids: 87.2;Endometrial ciliated cells: 109.2;NK-cells: 53.5;Respiratory ciliated cells: 199.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.4" "Lineage enriched" "Detected in single" 5 "T-cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (9.79e-6)" "unprognostic (4.04e-2)" "unprognostic (1.15e-2)" "unprognostic (5.54e-3)" "unprognostic (2.85e-1)" "unprognostic (5.45e-5)" "unprognostic (5.12e-3)" "unprognostic (9.11e-2)" "unprognostic (1.82e-2)" "unprognostic (7.59e-2)" "unprognostic (1.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.05e-5)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.65e-2)" "unprognostic (7.12e-3)" 0.2 0.1 2.5 1.2 1.8 0.5 0.1 1.0 0.4 0.5 1.5 0.1 0.4 0.6 0.2 0.3 13.7 0.6 0.1 2.1 2.5 0.0 0.3 3.5 4.0 11.8 11.2 0.0 0.1 0.0 0.0 0.0 6.3 0.1 0.3 0.0 0.2 0.1 0.0 0.0 0.5 0.1 10.6 2.2 0.5 1.2 1.6 0.3 0.2 0.0 1.3 0.3 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.0 0.3 1.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.4 2.5 1.8 1.0 0.4 2.1 2.5 11.8 11.2 6.3 10.6 1.6 4.9 0.4 3.2 4.1 0.7 1.4 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.4 0.0 24.2 0.0 0.0 0.0 37.9 0.0 0.0 0.1 87.2 109.2 0.6 0.1 0.0 0.8 0.2 0.0 0.0 0.4 3.1 1.7 1.3 0.0 0.0 0.1 0.1 0.0 0.2 0.0 8.2 0.8 0.0 24.1 0.3 1.2 0.0 1.9 0.1 0.0 53.5 0.0 2.9 0.1 0.0 0.0 12.4 0.1 0.0 0.2 199.1 0.0 0.0 0.5 0.9 1.8 0.3 0.5 0.1 0.0 27.4 0.0 0.0 0.1 DTX1 "hDx-1, RNF140" ENSG00000135144 "Deltex E3 ubiquitin ligase 1" Q86Y01 12 113056709-113098028 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;lymphoid tissue: 11.8" "Group enriched" "Detected in many" 6 "Astrocytes: 48.3;Horizontal cells: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Daudi: 109.1;REH: 45.1;U-698: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051249, HPA055275" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA051249: , HPA055275: AB_2682769" "unprognostic (2.13e-3)" "unprognostic (3.20e-3)" "unprognostic (4.24e-4)" "unprognostic (2.01e-1)" "unprognostic (7.48e-3)" "unprognostic (1.59e-3)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (9.55e-2)" "unprognostic (6.87e-2)" "unprognostic (2.19e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.41e-2)" "unprognostic (4.70e-1)" "unprognostic (1.63e-1)" "unprognostic (4.78e-3)" 9.0 1.7 6.5 5.7 6.8 2.7 6.4 3.2 5.9 2.4 0.2 0.8 1.3 1.5 0.3 0.9 1.8 0.8 1.2 5.2 11.1 3.5 8.9 0.8 11.1 5.2 8.8 0.4 1.6 0.0 3.3 0.3 5.1 0.8 0.1 2.9 2.6 0.3 0.5 1.0 3.5 0.3 3.7 11.8 0.9 1.9 10.5 0.5 2.2 0.1 6.0 0.5 0.6 2.4 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 109.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.3 4.6 0.0 2.0 0.2 0.0 45.1 0.2 2.6 0.0 0.0 2.7 7.1 0.4 0.4 2.5 0.0 0.1 0.2 1.2 0.0 4.0 0.0 0.1 0.5 0.2 110.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.5 6.8 3.2 5.9 5.2 11.1 5.2 8.8 5.1 3.7 10.5 2.4 0.7 0.0 0.0 48.3 8.8 1.0 0.0 0.0 0.0 4.7 0.2 0.6 0.7 0.0 0.0 1.8 8.4 0.0 0.3 0.1 7.9 2.5 0.7 0.7 17.5 1.7 0.0 0.0 10.6 0.0 0.0 4.5 0.5 0.4 7.0 0.0 0.4 12.4 0.8 171.6 13.8 0.1 0.0 0.3 0.6 1.7 7.8 0.2 3.6 2.8 0.0 11.4 2.1 13.0 1.0 0.2 0.1 7.5 2.5 0.0 0.0 0.2 0.0 2.8 0.0 0.4 1.3 0.8 2.4 0.0 0.4 0.0 2.2 0.8 0.0 0.0 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143169-96145440 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 129.5" "Cell type enhanced" "Detected in many" "dendritic cells: 919.7;Glandular and luminal cells: 321.1;Langerhans cells: 924.0;Macrophages: 353.9;T-cells: 764.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebral cortex: 55.0" "Immune cell enhanced" "Detected in all" "gdT-cell: 199.3" "Group enriched" "Detected in all" 10 "NK-cells: 148.1;T-cells: 199.3" "Cell line enhanced" "Detected in many" "Daudi: 30.4;HeLa: 29.7;JURKAT: 27.6;Karpas-707: 33.8;NB-4: 29.1;RT4: 34.2;SCLC-21H: 29.6;U-698: 43.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA071920 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane" Nucleoplasm "HPA071920: AB_2686472" "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 17.0 6.0 7.6 18.6 11.6 129.5 5.5 7.5 55.0 8.1 9.2 4.5 1.6 7.0 7.7 6.8 7.6 12.5 19.5 13.4 6.2 12.7 7.5 18.2 47.1 8.0 6.3 7.8 2.3 1.7 35.1 1.3 6.7 17.6 2.0 0.4 3.9 61.5 2.8 26.0 11.8 3.4 6.7 42.0 7.4 3.6 6.9 47.3 6.7 3.7 24.6 39.5 9.0 9.3 3.2 0.0 0.2 0.2 0.4 0.5 4.4 3.7 0.0 5.3 5.1 8.9 0.6 30.4 10.6 4.1 0.0 2.2 7.5 0.0 1.0 0.5 0.0 0.7 29.7 0.0 1.9 12.8 2.6 0.9 2.0 0.9 0.0 0.1 0.0 27.6 0.0 33.8 0.2 5.2 25.5 29.1 6.5 0.8 10.6 0.0 0.4 24.3 0.2 34.2 29.6 1.5 1.4 0.3 5.6 0.0 2.0 14.4 0.1 0.0 7.9 0.0 1.7 2.3 3.9 43.2 0.0 13.9 0.3 2.3 4.3 1.0 199.3 10.5 95.4 17.5 46.7 176.2 10.7 13.9 32.0 99.3 6.1 148.1 9.1 3.0 16.1 40.5 7.6 11.6 7.5 55.0 13.4 6.2 8.0 6.3 6.7 6.7 6.9 9.3 50.8 0.0 7.7 0.7 303.7 96.7 155.0 31.3 70.6 27.8 65.8 72.0 37.8 2.8 12.0 9.2 22.9 0.9 919.7 20.4 1.9 0.9 0.9 115.6 62.7 28.7 87.8 50.5 5.2 1.4 1.7 22.8 86.6 321.1 104.3 7.4 12.8 3.9 80.2 0.0 1.4 37.5 8.2 40.4 924.0 1.4 1.8 353.9 144.1 1.9 3.4 1.5 90.6 1.0 0.5 1.0 2.5 1.9 268.5 70.4 1.6 1.4 2.7 3.6 0.0 14.7 26.6 0.6 4.8 50.4 109.7 1.6 764.7 3.0 51.6 41.1 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 384.1;Late spermatids: 774.5;Spermatocytes: 222.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" 5.0 3.4 8.6 2.5 8.5 0.1 4.4 6.9 9.4 12.4 5.7 10.7 1.0 12.6 7.2 3.2 12.4 5.1 4.3 7.7 8.7 11.4 1.1 4.6 2.2 7.0 8.1 16.3 9.9 0.4 10.3 2.5 6.1 6.4 1.8 4.0 2.3 6.2 1.3 1.6 4.0 6.1 5.6 1.5 4.7 14.8 11.5 0.8 2.4 2.1 1.7 7.9 7.1 7.1 1.1 4.2 17.5 15.5 14.5 16.2 3.6 11.0 13.2 12.7 15.2 0.2 0.0 0.0 2.5 9.4 5.5 0.0 11.7 3.8 14.8 1.1 9.6 15.6 4.4 11.0 9.2 0.1 0.0 11.7 0.4 4.2 5.8 23.1 9.1 1.1 0.0 0.1 11.4 0.0 0.0 0.0 8.6 0.0 0.4 0.0 10.1 0.0 15.4 1.8 4.2 9.9 8.3 0.0 0.6 22.4 0.0 7.3 1.3 12.3 5.3 1.8 8.8 0.0 0.0 0.0 3.5 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 6.9 9.4 7.7 8.7 7.0 8.1 6.1 5.6 11.5 7.1 2.4 0.0 0.0 63.6 0.0 0.6 1.1 3.1 4.6 18.7 0.6 3.4 3.5 2.8 3.9 1.8 4.2 4.5 0.0 0.0 7.9 20.8 384.1 37.2 34.1 2.5 0.0 0.0 86.8 0.2 2.6 19.0 0.5 2.7 0.0 3.1 2.9 0.4 0.7 6.7 95.7 0.0 4.1 0.3 1.5 774.5 38.8 1.2 3.6 19.7 2.0 8.3 0.0 106.6 5.1 0.6 0.0 43.6 0.0 0.8 0.0 24.4 19.4 1.5 19.7 18.2 15.8 222.8 12.6 1.2 1.0 1.8 0.5 20.8 0.0 0.3 EAF2 "BM040, TRAITS, U19" ENSG00000145088 "ELL associated factor 2" Q96CJ1 3 121835183-121886526 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 71.8;lymphoid tissue: 53.6" "Cell type enhanced" "Detected in many" "B-cells: 73.7;Plasma cells: 144.1;Proximal tubular cells: 128.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 104.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.5;HL-60: 114.9;THP-1: 59.9;U-698: 93.5;U-937: 64.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA008411 Enhanced NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA008411: AB_1847950" "unprognostic (3.43e-1)" "prognostic favorable (2.25e-9)" "unprognostic (1.48e-1)" "prognostic favorable (2.66e-4)" "unprognostic (1.00e-1)" "unprognostic (3.18e-2)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (1.14e-1)" "unprognostic (2.08e-2)" "unprognostic (2.55e-1)" "unprognostic (1.81e-1)" "unprognostic (9.04e-2)" "unprognostic (8.34e-2)" 4.3 2.6 2.3 19.5 2.0 71.8 10.0 2.1 3.1 5.5 1.5 10.3 8.9 2.0 4.9 2.7 1.4 5.0 1.7 2.7 2.4 30.2 3.5 4.3 53.6 2.1 2.4 1.0 4.2 3.1 3.3 2.9 2.2 21.0 11.6 1.7 7.6 8.4 0.8 1.0 7.7 3.5 1.4 16.9 8.2 4.6 3.0 7.7 1.7 1.3 43.4 7.8 1.4 2.0 3.5 3.0 2.0 2.5 0.7 2.1 6.0 1.3 0.8 2.4 4.4 5.8 2.0 73.5 1.5 0.3 7.7 5.7 5.0 3.0 6.0 35.8 2.9 42.4 3.0 11.1 1.0 114.9 44.7 1.0 6.9 2.8 2.6 0.0 2.3 10.0 5.0 14.2 1.1 1.0 16.3 15.1 2.9 13.8 2.5 17.1 6.4 11.2 2.4 4.3 2.5 0.6 2.1 2.0 5.7 5.5 1.8 59.9 0.7 1.5 2.4 1.4 3.4 25.4 12.2 93.5 2.8 64.0 4.7 11.9 18.8 42.8 1.4 41.2 2.8 104.4 2.2 1.5 22.5 97.4 2.9 1.6 3.5 1.8 54.7 30.5 2.7 13.1 2.3 2.0 2.1 3.1 2.7 2.4 2.1 2.4 2.2 1.4 3.0 2.0 4.5 3.2 4.2 48.0 73.7 2.4 6.9 25.0 6.2 1.3 5.9 6.6 4.3 0.0 16.5 1.8 4.2 15.5 15.3 2.9 17.6 4.4 36.4 4.3 2.0 2.5 1.2 10.3 17.3 17.6 2.2 4.9 7.7 7.7 10.1 2.5 3.9 1.6 16.5 0.0 28.6 5.7 16.2 32.4 15.7 4.6 5.0 29.8 16.0 8.4 29.5 9.4 6.2 12.1 7.7 4.2 4.7 3.0 144.1 11.1 2.4 128.0 9.1 5.3 0.0 4.5 4.6 37.6 18.1 2.3 2.4 7.7 11.1 2.2 3.5 5.9 EBF2 "COE2, FLJ11500" ENSG00000221818 "EBF transcription factor 2" Q9HAK2 8 25841725-26045413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.8" "Cell type enhanced" "Detected in some" "Adipocytes: 11.9;Fibroblasts: 23.2;Microglial cells: 13.1;Sertoli cells: 39.5;Smooth muscle cells: 53.4" "Cancer enhanced" "Detected in many" "renal cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 22.7;ASC TERT1: 45.7;HSkMC: 46.9;hTEC/SVTERT24-B: 26.7;U-138 MG: 17.1;U-2197: 22.7;U-87 MG: 19.1" "Group enriched" "Detected in many" 4 "basal ganglia: 5.7;cerebellum: 3.1;hypothalamus: 2.0;midbrain: 4.4;pons and medulla: 2.8" "Region enriched" "Detected in many" 5 "spinal cord: 8.7" "HPA003954, HPA055101" Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA003954: , HPA055101: " "unprognostic (3.70e-1)" "unprognostic (3.88e-3)" "unprognostic (2.69e-2)" "unprognostic (2.47e-3)" "unprognostic (1.03e-1)" "unprognostic (6.10e-2)" "unprognostic (5.92e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-2)" "unprognostic (6.13e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (7.41e-4)" "unprognostic (2.28e-1)" "unprognostic (3.80e-2)" "unprognostic (1.82e-2)" 17.8 0.7 0.2 0.9 0.5 0.0 8.0 0.2 0.1 0.7 0.1 1.4 0.0 0.8 1.9 0.8 4.0 2.6 9.8 0.0 0.7 0.5 0.0 0.6 0.6 1.3 3.1 1.0 0.8 2.2 0.4 0.5 2.7 0.5 0.4 0.2 1.4 0.4 4.7 1.5 0.7 1.7 3.8 0.0 0.8 1.1 0.9 1.4 6.2 9.6 0.2 1.9 1.2 0.3 0.0 0.0 0.8 0.0 22.7 45.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 26.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 17.1 0.2 22.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.7 1.3 3.1 2.7 3.8 0.9 0.3 11.9 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.6 0.1 0.2 0.3 5.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 5.6 0.0 0.0 0.5 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 3.2 5.9 0.6 0.0 13.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 39.5 2.6 53.4 1.0 0.2 0.4 0.3 0.0 0.2 0.1 0.0 0.1 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 EBF4 "COE4, KIAA1442, O/E-4, RP5-860F19.3" ENSG00000088881 "EBF family member 4" Q9BQW3 20 2692874-2760108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.9;Cholangiocytes: 21.5;Endometrial stromal cells: 18.6;Oligodendrocyte precursor cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 7.9;HEK 293: 8.4;SH-SY5Y: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (9.57e-2)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (7.79e-3)" "unprognostic (3.82e-1)" "prognostic favorable (2.47e-5)" "unprognostic (2.68e-2)" "unprognostic (5.58e-3)" "unprognostic (1.87e-3)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.87e-3)" 2.6 3.5 12.1 2.7 13.5 0.3 2.7 9.1 15.0 5.0 3.0 3.2 2.8 19.0 2.2 4.1 6.7 5.7 2.9 12.9 11.1 2.6 1.1 3.6 2.3 13.4 11.4 13.7 3.8 14.4 2.9 5.7 9.9 12.4 1.9 3.3 5.6 11.1 1.1 2.8 3.8 12.1 10.6 2.2 3.9 1.2 13.1 0.6 18.0 1.5 1.8 3.0 2.0 17.4 0.0 0.7 4.4 4.4 0.1 1.1 0.9 1.2 3.2 2.2 1.1 0.6 0.4 0.0 2.5 0.5 7.9 0.2 1.5 0.2 1.3 6.2 8.4 0.0 0.0 0.2 2.8 0.0 0.0 0.1 1.0 1.0 0.0 0.8 0.3 1.9 0.0 0.0 0.0 0.4 0.1 6.9 0.6 0.0 0.2 6.4 1.2 0.5 0.0 2.7 3.3 21.2 1.2 0.1 1.9 4.2 2.4 0.3 1.7 0.3 1.0 0.2 3.8 1.4 0.2 1.5 0.0 0.9 3.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.1 13.5 9.1 15.0 12.9 11.1 13.4 11.4 9.9 10.6 13.1 17.4 4.1 0.0 1.1 18.9 0.3 3.4 15.6 3.0 6.8 7.7 18.1 11.0 2.2 21.5 5.5 1.8 0.0 0.2 5.1 0.2 0.0 2.0 0.4 1.2 18.6 3.2 0.0 0.0 3.1 0.4 0.1 5.1 1.1 1.1 0.0 1.9 6.4 5.7 0.3 5.0 12.2 0.2 4.1 0.8 1.4 0.8 3.4 0.3 1.8 10.3 0.0 5.5 2.1 52.3 17.9 0.3 1.7 7.2 0.4 11.3 0.0 0.2 4.9 2.3 6.6 3.3 5.1 0.6 1.4 0.6 1.0 0.3 0.7 0.1 0.4 9.3 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.9;skeletal muscle: 906.9" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 796.9;Proximal tubular cells: 880.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 720000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" 216.0 343.0 51.2 47.6 53.7 62.3 194.2 54.1 60.3 124.9 58.6 232.9 93.5 115.3 32.3 168.4 114.0 66.8 749.9 49.3 52.5 271.6 556.1 122.1 67.8 51.8 51.8 107.2 141.4 56.0 77.1 67.1 53.4 99.5 99.9 12.8 138.6 43.3 906.9 149.0 167.4 59.7 50.6 192.3 180.5 100.7 55.0 51.0 117.9 455.1 65.7 142.4 132.4 53.3 64.0 273.8 42.0 68.8 161.0 82.0 61.8 31.7 53.2 26.6 27.1 178.8 124.8 98.6 117.2 72.8 24.1 30.1 70.9 72.9 21.1 345.3 37.7 120.7 76.5 146.1 161.3 131.9 116.9 109.0 186.6 35.1 61.2 52.3 63.4 127.3 58.4 160.8 59.6 120.0 91.8 82.2 27.8 278.8 65.9 101.8 126.2 199.0 168.7 142.6 51.4 67.2 161.0 77.1 86.5 27.3 106.4 288.4 53.7 45.5 39.3 46.5 29.6 121.0 153.2 96.4 71.4 164.9 90.7 316.1 312.9 268.0 253.6 248.2 237.2 368.4 243.5 249.1 308.6 361.3 216.5 242.4 41.6 342.7 212.8 221.5 391.8 541.8 51.2 53.7 54.1 60.3 49.3 52.5 51.8 51.8 53.4 50.6 55.0 53.3 125.4 86.6 104.7 13.1 111.1 82.2 220.0 320.8 80.8 22.4 124.0 143.8 302.7 205.9 203.2 145.3 16.7 796.9 103.4 257.7 510.6 195.4 64.5 95.7 56.9 96.4 189.2 99.9 7.1 90.1 370.6 104.1 112.7 77.0 120.9 177.6 90.7 549.4 277.6 37.0 8.6 298.9 193.3 99.0 85.2 56.7 130.8 97.5 145.9 8.4 205.1 53.0 113.3 7.1 16.0 97.0 257.5 143.0 122.1 100.1 383.0 880.0 182.6 21.4 78.9 88.4 119.7 73.3 51.3 121.6 90.8 580.9 118.6 624.2 350.0 218.1 ECHDC3 FLJ20909 ENSG00000134463 "Enoyl-CoA hydratase domain containing 3" Q96DC8 10 11742366-11764070 "Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.6;skeletal muscle: 128.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 81.2;Distal tubular cells: 144.8;Hepatocytes: 152.0;Proximal tubular cells: 209.9" "Cancer enhanced" "Detected in all" "liver cancer: 35.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 15.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "A-431: 52.9;BEWO: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038306 Enhanced NA NA 120000 "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038306: AB_10672586" "unprognostic (8.74e-2)" "unprognostic (1.69e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (2.37e-2)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (5.07e-1)" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (3.53e-1)" "prognostic favorable (3.43e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (3.91e-4)" 71.7 29.3 2.6 3.2 2.4 7.0 52.8 2.5 2.5 15.9 17.5 6.7 1.8 11.0 2.2 22.9 11.1 1.8 67.0 2.6 4.3 63.0 161.6 17.5 3.7 3.0 2.7 10.5 29.7 1.8 10.8 7.9 2.9 13.7 3.6 2.0 28.6 13.7 128.4 21.7 6.0 4.4 2.9 15.7 26.6 14.3 3.8 2.8 17.9 60.1 5.5 9.3 17.8 3.3 52.9 7.6 0.1 0.0 0.0 0.0 28.7 6.3 0.0 4.6 4.0 19.1 0.4 0.0 5.8 14.1 1.3 12.5 11.9 1.9 2.0 0.1 0.5 0.0 7.6 0.0 20.5 0.0 7.4 14.1 11.8 4.8 0.0 0.4 9.3 0.0 19.6 0.0 1.4 7.3 0.0 0.2 13.3 0.1 0.0 16.3 0.0 0.0 3.6 0.0 5.5 8.4 0.0 13.1 0.0 16.5 20.5 2.6 2.8 0.0 5.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 3.6 2.9 1.7 15.4 0.0 0.6 0.0 0.2 0.1 0.5 1.7 1.7 0.3 0.0 3.6 0.5 0.7 0.6 0.0 0.3 2.6 2.4 2.5 2.5 2.6 4.3 3.0 2.7 2.9 2.9 3.8 3.3 2.7 19.2 11.8 0.0 3.6 4.5 13.8 2.7 0.0 0.9 16.7 27.2 42.2 17.2 6.4 16.5 2.1 81.2 0.1 1.3 144.8 33.6 4.0 2.3 5.9 3.5 0.0 1.7 0.3 29.8 32.9 6.0 16.3 4.6 0.0 49.5 4.6 152.0 13.1 0.0 0.2 0.6 6.1 14.1 2.2 6.3 2.8 10.6 8.8 1.0 6.8 13.1 0.0 0.0 0.5 13.6 1.2 3.4 6.4 26.1 0.9 209.9 0.4 2.7 19.7 12.0 12.0 22.1 9.6 0.4 5.7 28.9 1.5 4.9 1.9 6.8 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 117.1;Leydig cells: 43.8;Peritubular cells: 68.1;Sertoli cells: 52.6;Smooth muscle cells: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 9.4;ASC TERT1: 18.2;HHSteC: 9.3;LHCN-M2: 22.7;SH-SY5Y: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 14.0 5.5 2.1 3.3 2.8 0.0 8.3 2.7 4.2 57.0 2.1 3.2 3.4 44.7 23.3 4.4 18.4 12.7 26.0 2.2 2.2 4.2 3.1 22.7 3.8 2.9 3.1 37.5 1.1 3.4 2.8 12.1 2.9 30.7 3.4 0.3 6.4 113.9 4.0 4.6 2.9 45.1 2.5 8.4 5.4 6.2 2.9 4.9 6.8 5.5 2.6 11.8 24.0 3.0 0.0 1.2 5.2 0.0 9.4 18.2 0.0 2.9 3.8 0.4 0.1 0.2 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.7 0.2 0.0 1.9 0.0 2.8 0.0 9.3 0.0 0.0 6.9 0.6 0.5 0.0 3.4 0.0 0.0 0.0 1.4 22.7 0.3 0.0 0.1 1.5 0.0 1.1 0.0 0.9 0.1 1.3 1.0 0.0 16.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 3.6 0.7 0.0 0.0 1.3 0.4 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.8 2.7 4.2 2.2 2.2 2.9 3.1 2.9 2.5 2.9 3.0 7.7 3.2 5.3 1.0 0.0 3.1 0.8 1.7 27.3 0.1 0.8 5.2 24.9 0.0 4.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 2.9 3.4 117.1 8.0 0.0 0.0 5.3 0.0 0.1 15.9 0.0 2.7 0.0 14.3 0.0 0.0 0.6 0.0 22.5 0.0 0.0 0.0 3.9 3.5 43.8 0.8 3.6 9.4 0.0 0.1 0.0 2.0 1.0 0.2 0.0 68.1 0.0 1.4 0.0 0.5 0.0 0.5 52.6 0.6 108.6 0.7 0.7 7.1 2.7 0.1 0.9 0.3 0.0 0.4 EEF1A2 "EEF1AL, HS1, STN, STNL" ENSG00000101210 "Eukaryotic translation elongation factor 1 alpha 2" Q05639 20 63488013-63499239 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 1638.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 130.8;Cardiomyocytes: 125.5;Horizontal cells: 269.2;Rod photoreceptor cells: 50.9;Skeletal myocytes: 49.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 347.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 240.0;MCF7: 405.9;SCLC-21H: 187.0;T-47d: 157.2;U-2 OS: 202.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034019, HPA051759, HPA053862, HPA056990" Approved Approved Nucleoli,Cytosol NA NA 55000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 37: Myocytes - Muscle contraction" Cytosol Nucleoli "CAB034019: AB_1562672, HPA051759: AB_2681595, HPA053862: AB_2797248, HPA056990: AB_2683302" "unprognostic (1.40e-2)" "unprognostic (6.82e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (5.17e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (4.85e-1)" "unprognostic (1.68e-1)" "unprognostic (3.02e-2)" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (2.30e-1)" "unprognostic (1.86e-1)" "unprognostic (8.29e-3)" "unprognostic (1.82e-1)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" 0.9 32.7 59.3 1.4 81.3 0.0 1.7 17.1 347.2 2.8 0.0 5.1 0.7 0.3 1.1 9.7 0.4 2.4 358.0 73.4 97.3 1.3 3.0 0.8 0.6 95.0 2.9 0.5 6.5 16.2 111.5 0.0 76.3 9.6 0.4 37.2 19.5 0.8 1638.0 6.8 1.9 0.8 0.0 0.3 8.5 1.2 30.7 0.2 0.7 320.7 0.1 2.2 1.8 125.0 0.5 71.0 0.8 16.8 0.0 0.6 7.9 10.0 1.3 51.6 16.3 9.8 41.5 0.0 110.4 0.5 13.4 38.8 240.0 0.7 115.9 0.5 13.1 0.0 24.1 4.1 2.9 0.0 13.4 1.4 2.2 0.1 1.0 0.2 0.0 0.0 3.4 0.2 0.5 405.9 1.4 0.5 11.4 95.6 96.5 8.0 0.2 10.2 2.4 3.9 187.0 89.9 90.0 12.6 1.6 2.2 157.2 3.8 0.0 0.3 202.9 0.7 1.8 0.3 0.9 1.4 0.9 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 59.3 81.3 17.1 347.2 73.4 97.3 95.0 2.9 76.3 0.0 30.7 125.0 0.1 0.0 0.0 9.4 0.7 0.4 0.9 0.0 0.0 130.8 11.8 4.6 125.5 1.5 0.6 0.0 12.5 0.0 1.1 0.4 0.0 1.3 0.2 0.5 0.3 2.2 0.0 0.0 35.5 0.2 0.2 3.6 4.6 1.4 5.7 1.0 1.1 0.1 0.0 269.2 37.2 0.0 0.0 0.3 0.7 0.5 0.0 0.6 0.0 15.0 0.0 11.7 0.0 14.6 12.7 0.3 0.0 0.0 0.3 2.6 0.0 0.5 0.0 50.9 0.0 49.9 3.4 0.0 0.3 0.0 1.8 0.0 1.5 0.0 0.5 1.1 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 122.8;Leydig cells: 93.5;Muller glia cells: 84.8;Peritubular cells: 107.2;Smooth muscle cells: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 159.7;fHDF/TERT166: 232.6;HSkMC: 155.3;hTERT-RPE1: 159.1;LHCN-M2: 134.5;U-138 MG: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" 38.4 18.0 19.8 13.8 21.1 2.8 29.5 18.8 26.7 46.6 22.1 39.6 9.3 55.2 8.3 12.8 35.8 33.5 61.6 19.1 20.4 26.8 7.0 32.1 9.1 24.9 20.0 47.0 19.9 26.8 15.2 22.4 21.4 31.1 6.5 5.9 17.4 35.2 21.2 14.9 16.2 32.3 20.3 16.1 20.6 8.2 21.4 5.6 39.1 22.0 5.0 33.1 30.7 19.1 0.5 0.2 2.1 47.3 54.3 108.0 0.8 125.8 159.7 48.1 44.8 0.0 4.3 0.7 9.3 232.6 0.7 0.9 0.0 1.3 12.1 5.4 0.1 1.1 3.2 8.0 89.1 0.0 0.4 155.3 0.4 18.9 1.0 159.1 28.5 1.0 0.3 8.0 134.5 0.4 0.2 20.7 1.6 0.2 0.6 0.4 0.3 3.2 1.6 0.6 0.7 14.1 0.2 1.3 1.5 6.6 1.5 10.0 64.6 114.2 24.7 52.6 0.6 10.9 0.7 0.3 42.6 0.8 19.7 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.2 19.8 21.1 18.8 26.7 19.1 20.4 24.9 20.0 21.4 20.3 21.4 19.1 30.8 35.3 7.4 29.0 1.5 13.5 38.9 33.9 8.6 7.7 10.2 27.6 46.0 15.7 11.4 18.4 0.0 2.4 2.3 0.3 7.9 28.7 15.6 3.4 57.1 27.9 0.0 0.4 1.1 0.2 3.9 122.8 2.6 4.1 0.0 74.3 42.8 1.8 9.8 6.7 2.9 0.3 4.1 3.5 19.1 33.3 93.5 3.0 24.9 9.4 0.7 84.8 2.1 9.5 1.6 2.6 0.1 107.2 1.4 30.1 0.2 21.2 9.0 4.8 39.5 41.1 113.2 35.9 3.3 1.1 10.1 5.9 2.4 78.5 0.3 14.2 EFHD1 FLJ13612 ENSG00000115468 "EF-hand domain family member D1" Q9BUP0 2 232606057-232682780 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 414.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 241.8;Breast myoepithelial cells: 129.0;Distal tubular cells: 393.2;Oligodendrocytes: 173.4;Sertoli cells: 197.2;Smooth muscle cells: 130.9;Syncytiotrophoblasts: 263.9" "Cancer enriched" "Detected in all" 5 "breast cancer: 100.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 125.8;RPTEC TERT1: 68.6;SK-BR-3: 301.8;T-47d: 236.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049331, HPA056959" Enhanced Supported "Nucleoli fibrillar center,Golgi apparatus" No NA 14000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "Nucleoli fibrillar center" "HPA049331: AB_2680716, HPA056959: AB_2683288" "unprognostic (9.51e-3)" "unprognostic (2.21e-2)" "unprognostic (4.78e-3)" "unprognostic (3.25e-1)" "unprognostic (3.40e-1)" "unprognostic (9.70e-2)" "unprognostic (9.02e-2)" "unprognostic (1.13e-1)" "unprognostic (3.29e-3)" "unprognostic (1.21e-1)" "unprognostic (5.57e-2)" "unprognostic (9.99e-2)" "prognostic favorable (2.93e-7)" "unprognostic (2.00e-2)" "unprognostic (1.84e-1)" "unprognostic (2.51e-2)" "unprognostic (2.29e-3)" 86.3 7.0 199.7 3.7 303.2 0.8 180.7 244.9 261.3 86.9 129.9 16.9 4.4 72.4 33.7 9.6 73.7 12.0 46.0 196.6 217.4 186.2 54.6 15.3 3.9 253.6 258.7 76.5 86.5 10.5 16.5 77.9 261.8 25.6 5.7 9.5 22.2 27.7 35.5 30.9 16.2 20.6 201.4 52.5 17.6 20.1 237.8 3.0 32.7 42.7 2.4 22.0 44.5 414.6 0.0 3.4 5.7 1.4 2.2 0.1 125.8 26.8 2.1 2.3 1.9 0.9 0.6 0.1 2.0 11.6 2.9 0.2 19.0 0.0 0.3 0.5 9.2 0.0 2.4 1.9 0.0 0.1 0.3 1.0 0.4 0.2 0.0 0.4 0.0 5.5 3.9 0.5 0.5 2.3 0.6 0.2 8.4 0.0 0.2 0.6 7.2 0.4 68.6 0.7 0.3 3.2 9.1 301.8 18.3 42.3 236.9 2.6 0.0 0.0 1.8 0.4 0.8 0.2 0.1 0.1 0.3 0.1 13.4 1.0 0.2 0.1 0.2 0.1 0.4 0.3 0.3 0.4 0.1 0.1 0.6 0.6 2.2 0.1 0.1 0.2 0.1 0.1 199.7 303.2 244.9 261.3 196.6 217.4 253.6 258.7 261.8 201.4 237.8 414.6 15.6 0.0 0.0 37.5 1.5 3.6 2.8 1.3 1.2 0.5 241.8 129.0 7.4 1.5 4.6 35.0 0.0 112.0 3.0 0.3 393.2 0.0 9.0 1.1 37.8 16.8 0.0 2.7 2.6 0.0 19.7 41.1 0.0 1.7 0.0 3.2 6.4 89.4 8.7 0.0 5.3 0.1 59.0 1.3 3.0 7.0 44.4 2.1 8.8 18.7 0.0 48.0 0.0 1.5 173.4 0.0 0.0 57.2 0.1 4.6 0.0 116.5 1.9 1.4 197.2 8.7 130.9 17.3 13.6 0.4 3.1 263.9 2.5 1.5 0.3 2.0 EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 372.4;NK-cells: 416.1;Pancreatic endocrine cells: 481.2;Urothelial cells: 431.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 370.3" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 220000 "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA048961: AB_2680572" "unprognostic (1.37e-3)" "unprognostic (3.69e-1)" "unprognostic (7.83e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (9.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.31e-9)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "prognostic favorable (2.70e-4)" "prognostic favorable (3.60e-5)" 37.7 78.9 52.5 77.7 56.8 174.3 27.5 31.6 76.9 32.8 20.4 74.3 83.3 33.7 5.9 58.7 29.3 32.9 28.5 75.4 34.9 23.0 33.3 60.0 46.3 100.2 31.4 26.9 75.7 10.7 28.6 21.4 101.7 44.6 29.6 2.7 27.3 19.0 6.4 35.9 96.4 17.3 29.6 140.0 92.0 95.2 36.1 25.2 41.6 4.9 29.5 62.6 40.5 62.9 370.3 91.8 8.8 23.8 14.1 30.0 46.8 46.0 43.4 42.7 40.5 35.5 98.8 79.6 141.6 32.1 54.8 88.1 24.5 80.9 27.0 99.8 47.8 19.1 21.6 57.4 22.5 98.1 160.1 23.9 27.2 87.0 21.9 19.9 55.5 35.5 46.4 37.6 26.6 36.8 50.8 188.6 11.6 50.1 112.9 67.2 82.1 63.4 25.3 76.2 20.1 15.6 40.5 34.3 76.8 6.9 15.1 104.8 105.4 62.5 66.9 196.7 74.8 25.4 63.8 34.9 87.4 193.2 86.8 16.3 33.8 52.5 44.0 34.4 12.7 3.9 9.8 20.9 29.5 4.2 4.6 18.0 133.2 28.5 30.0 10.3 7.6 17.0 52.5 56.8 31.6 76.9 75.4 34.9 100.2 31.4 101.7 29.6 36.1 62.9 54.2 3.2 12.2 5.9 44.1 66.2 123.7 25.2 26.7 1.8 21.3 23.0 7.2 32.9 24.4 22.0 10.4 23.7 372.4 280.0 19.6 69.6 93.6 55.4 28.8 52.6 61.7 28.0 33.9 259.4 222.8 31.1 157.0 69.4 44.5 49.4 23.6 20.9 219.3 0.0 21.9 160.8 24.4 217.1 188.2 221.2 9.9 246.9 23.2 13.1 171.3 4.9 416.1 0.5 3.7 481.2 190.5 6.8 62.9 112.2 305.8 28.1 25.7 5.0 46.0 26.7 28.5 5.4 5.7 48.9 68.5 53.4 120.1 178.3 117.8 431.4 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EHBP1L1 "DKFZp762C186, TANGERIN" ENSG00000173442 "EH domain binding protein 1 like 1" Q8N3D4 11 65576046-65592650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 255.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.1;Kupffer cells: 79.7;Macrophages: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039479, HPA073476" Enhanced Approved "Vesicles,Plasma membrane" NA NA 110000 "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Plasma membrane" "HPA039479: AB_10795678, HPA073476: " "unprognostic (1.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.84e-1)" "unprognostic (2.41e-3)" "unprognostic (2.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.36e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.10e-3)" "unprognostic (5.02e-2)" "unprognostic (3.50e-2)" "unprognostic (1.10e-1)" 27.2 9.9 7.5 51.9 6.2 59.7 21.5 5.9 9.4 35.9 7.3 108.1 26.0 56.1 5.7 45.4 48.0 18.0 45.6 7.1 6.3 17.7 10.8 39.6 30.7 9.8 8.1 19.6 8.1 4.1 9.8 16.3 7.7 45.2 12.2 0.4 22.9 39.5 255.7 22.6 46.6 32.8 8.0 73.3 41.0 7.3 9.4 14.5 13.0 70.7 16.6 71.3 40.8 9.0 40.6 41.0 1.3 21.8 10.5 26.4 8.2 31.4 22.9 14.8 7.8 13.7 34.9 14.0 52.4 45.8 41.2 55.9 7.6 29.7 3.4 39.3 1.2 32.4 51.0 12.0 10.0 7.1 30.1 22.7 19.8 37.2 6.8 26.9 15.2 20.8 50.5 55.9 13.8 34.5 12.4 27.5 1.8 15.1 34.8 33.6 0.2 46.8 13.7 20.0 0.9 17.2 17.4 15.2 32.9 3.0 21.9 33.7 26.3 40.3 42.9 57.3 0.6 98.5 66.6 7.3 60.2 18.8 23.9 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 7.5 6.2 5.9 9.4 7.1 6.3 9.8 8.1 7.7 8.0 9.4 9.0 33.1 0.0 6.9 6.2 23.9 10.1 8.5 2.9 15.9 1.4 12.2 14.2 22.0 7.2 7.4 1.8 0.0 3.4 27.3 79.1 0.0 3.6 0.2 11.9 12.2 26.0 4.2 61.6 4.4 5.1 1.4 13.8 61.2 14.2 2.5 5.3 18.9 5.7 32.6 0.0 2.2 16.3 2.0 79.7 33.9 1.7 11.5 67.6 7.2 15.0 49.1 0.7 20.6 1.5 1.3 27.8 53.0 38.0 19.5 11.6 19.5 0.4 8.6 1.1 26.3 27.3 30.7 2.7 5.9 15.3 14.8 2.6 23.2 23.0 21.9 17.0 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 EID1 "C15orf3, CRI1, EID-1" ENSG00000255302 "EP300 interacting inhibitor of differentiation 1" Q9Y6B2 15 48878134-48880173 "Predicted intracellular proteins" "Cell cycle, Differentiation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051122, HPA051123" Approved Supported Nucleoplasm NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA051122: AB_2681350, HPA051123: AB_2681351" "unprognostic (1.38e-1)" "unprognostic (6.69e-2)" "unprognostic (1.64e-1)" "unprognostic (3.18e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (1.10e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (6.75e-3)" "unprognostic (2.46e-1)" "unprognostic (3.62e-3)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.04e-2)" "unprognostic (2.13e-1)" "unprognostic (2.09e-1)" 128.6 206.3 96.9 95.4 103.7 61.0 112.0 98.7 153.6 149.8 107.2 143.9 81.6 161.0 132.1 96.6 134.9 120.9 280.1 103.9 111.3 147.9 125.1 99.5 112.0 102.6 101.7 186.7 102.0 144.8 130.1 93.3 100.5 156.1 71.3 158.4 98.3 147.3 278.8 57.6 79.0 141.8 102.1 115.3 84.2 67.9 104.5 117.2 138.5 227.6 83.9 113.1 81.4 123.2 131.5 109.1 260.9 231.6 239.9 316.9 16.4 337.6 304.5 220.3 294.3 95.0 58.0 174.9 305.3 207.0 155.5 115.4 130.2 130.8 247.9 484.1 127.1 300.6 235.8 4.1 186.0 183.0 132.2 278.1 115.1 146.1 91.9 221.4 262.8 151.2 182.3 162.6 258.5 188.7 134.6 174.1 0.5 98.9 97.4 185.1 302.6 290.6 287.4 142.3 233.8 234.6 210.2 80.2 401.2 212.7 145.0 240.6 262.9 322.4 177.7 305.6 299.3 208.4 616.7 125.1 264.6 410.0 230.0 345.0 311.5 275.5 221.3 285.3 209.2 168.3 249.4 231.8 358.1 183.2 179.6 165.3 40.4 230.0 297.5 354.9 332.4 440.1 96.9 103.7 98.7 153.6 103.9 111.3 102.6 101.7 100.5 102.1 104.5 123.2 327.4 387.8 207.7 31.3 127.5 175.5 139.9 459.5 138.9 345.3 188.5 286.4 480.8 183.0 329.9 261.1 120.9 351.6 168.0 46.0 606.5 386.5 17.5 116.0 324.4 356.8 233.7 219.2 38.0 268.0 151.2 443.4 88.2 116.7 188.0 173.8 339.8 166.2 211.3 238.9 43.5 114.0 301.1 208.1 262.0 49.2 702.4 189.7 487.4 30.9 302.2 844.1 213.1 28.6 80.9 191.0 102.1 651.4 134.3 81.4 91.9 446.5 240.2 329.9 322.1 350.7 379.1 98.6 75.0 125.9 145.6 109.6 180.7 463.2 101.5 96.9 EID2B "EID-3, FLJ38944" ENSG00000176401 "EP300 interacting inhibitor of differentiation 2B" Q96D98 19 39530987-39532852 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.1;Horizontal cells: 32.0;NK-cells: 27.8;Rod photoreceptor cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064185 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" "HPA064185: AB_2685207" "unprognostic (1.15e-1)" "unprognostic (8.53e-3)" "unprognostic (6.41e-3)" "unprognostic (1.08e-3)" "unprognostic (4.00e-1)" "unprognostic (7.08e-2)" "unprognostic (9.92e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (3.29e-1)" "prognostic favorable (2.57e-4)" "unprognostic (6.80e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-2)" "unprognostic (1.78e-1)" "unprognostic (2.77e-1)" "unprognostic (4.20e-2)" 2.4 3.6 7.2 2.0 6.9 1.2 2.0 7.8 7.1 3.9 4.5 3.7 1.3 4.1 2.6 1.1 4.1 1.2 3.0 6.4 9.4 2.6 1.0 2.2 3.1 5.1 5.7 5.1 1.4 1.8 10.3 1.1 5.8 2.9 0.9 9.4 1.3 2.0 2.1 1.0 2.5 1.5 4.7 3.3 1.9 5.2 8.1 2.5 3.6 1.2 1.5 3.0 2.3 5.5 2.0 4.1 4.6 5.1 2.9 2.7 1.0 3.1 2.4 5.0 4.5 0.6 1.3 4.0 1.7 1.9 2.5 0.6 2.3 2.1 3.7 6.3 6.3 1.8 5.3 2.5 2.5 1.8 3.1 2.7 1.5 2.8 1.4 1.9 2.2 8.9 2.0 5.6 2.5 1.8 3.6 3.1 1.2 0.7 2.2 4.6 4.2 2.0 2.5 0.6 6.3 3.9 6.1 0.2 2.5 1.8 0.5 1.0 1.5 3.7 6.6 3.6 4.1 4.0 6.1 3.0 2.0 4.3 2.0 0.4 1.9 3.9 2.8 2.1 2.7 3.6 3.5 4.1 2.4 3.1 6.5 4.3 0.6 4.6 2.2 2.4 2.4 2.1 7.2 6.9 7.8 7.1 6.4 9.4 5.1 5.7 5.8 4.7 8.1 5.5 3.9 6.4 1.1 3.9 8.5 1.5 1.3 3.5 1.8 30.1 1.6 2.7 5.5 7.2 6.3 9.2 25.0 3.0 6.4 0.2 11.7 4.0 1.8 5.3 6.0 4.3 6.1 4.6 9.0 3.0 1.2 6.3 2.0 0.7 4.5 9.1 3.3 1.8 3.7 32.0 9.2 0.5 4.1 4.1 5.3 1.2 15.2 4.6 8.8 4.7 5.5 23.2 27.8 3.0 5.5 1.8 1.3 11.3 5.6 0.6 0.2 4.9 10.8 30.2 13.1 3.5 5.3 22.1 8.8 0.5 0.6 0.8 7.8 8.0 0.1 0.4 EIF2B4 "DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta" ENSG00000115211 "Eukaryotic translation initiation factor 2B subunit delta" Q9UI10 2 27364352-27370457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 196.4;Late spermatids: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032234, HPA039993, HPA068855" Approved Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear membrane" "Actin filaments" "CAB032234: AB_668909, HPA039993: AB_2676790, HPA068855: " "unprognostic (2.26e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" "unprognostic (7.55e-2)" "unprognostic (2.37e-1)" "unprognostic (4.63e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.64e-2)" "unprognostic (2.18e-1)" "unprognostic (3.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.46e-8)" "unprognostic (1.79e-1)" "unprognostic (1.70e-1)" "unprognostic (8.76e-2)" "unprognostic (1.67e-2)" 21.4 24.8 23.3 15.2 24.3 10.7 20.7 24.0 23.8 21.3 22.5 31.7 14.6 21.0 16.9 27.8 20.3 13.4 28.0 23.2 23.7 18.2 21.5 18.1 17.2 24.4 24.3 19.8 31.4 20.4 20.3 18.8 24.0 25.4 18.4 19.3 24.6 20.8 51.8 29.3 18.4 22.8 23.2 18.6 24.7 38.1 24.4 18.9 18.1 35.2 22.9 24.1 21.4 24.1 38.7 59.8 44.3 34.6 58.4 42.7 48.4 41.0 43.7 55.7 37.3 89.2 16.9 49.7 38.7 48.7 46.6 27.6 62.5 50.8 36.2 37.4 40.7 61.7 39.3 104.5 51.1 58.2 23.0 41.3 51.1 69.2 51.6 40.4 53.3 37.2 59.5 24.9 53.0 35.2 28.8 61.7 49.1 59.8 38.9 52.9 69.9 43.2 50.0 32.7 34.3 37.4 34.1 53.8 42.6 39.6 31.3 23.4 52.8 40.1 47.0 35.4 49.7 50.9 65.7 74.7 33.9 47.9 38.6 56.6 53.9 38.8 32.1 48.1 44.6 31.1 31.6 32.6 52.5 25.3 30.2 32.9 7.7 30.8 52.2 38.6 43.8 43.2 23.3 24.3 24.0 23.8 23.2 23.7 24.4 24.3 24.0 23.2 24.4 24.1 19.9 12.8 14.8 9.8 17.5 35.9 18.9 32.0 15.4 22.6 28.0 18.7 33.0 14.3 27.0 22.0 66.7 40.9 27.8 23.4 19.6 29.0 196.4 22.3 23.9 19.9 24.0 8.2 6.6 33.4 25.0 24.6 14.8 17.6 31.6 16.9 25.7 34.4 24.3 10.1 6.5 24.8 28.5 20.7 28.0 299.6 23.3 16.5 23.2 2.8 29.5 23.2 16.5 6.0 8.8 26.7 27.1 24.8 28.4 21.2 23.0 27.6 24.9 58.9 19.7 17.0 34.9 71.5 38.9 14.5 34.8 46.1 24.3 23.8 20.5 14.4 EIF4EBP1 "4E-BP1, PHAS-I" ENSG00000187840 "Eukaryotic translation initiation factor 4E binding protein 1" Q13541 8 38030534-38060365 "Cancer-related genes, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 188.9;salivary gland: 164.2" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 730.0;Pancreatic endocrine cells: 277.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005032, CAB005039, HPA023501" Supported Supported Nucleoplasm,Cytosol NA NA 44000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "CAB005032: AB_562030, CAB005039: AB_562029, HPA023501: AB_1848095" "unprognostic (1.55e-2)" "unprognostic (2.45e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.86e-4)" "unprognostic (6.94e-2)" "unprognostic (2.69e-1)" "unprognostic (1.94e-2)" "unprognostic (3.27e-2)" "unprognostic (1.61e-1)" "unprognostic (1.16e-2)" "unprognostic (3.18e-3)" "unprognostic (7.21e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" "unprognostic (4.57e-2)" "unprognostic (5.72e-3)" 60.9 12.6 7.7 16.9 8.0 35.0 53.6 8.0 10.9 24.9 12.7 25.3 18.5 19.7 2.2 86.0 21.7 8.9 32.7 8.0 9.8 19.5 63.5 25.0 10.3 9.8 8.5 22.2 188.9 7.8 9.2 28.6 9.8 19.2 15.4 1.5 164.2 17.0 98.1 20.8 23.1 14.4 8.5 23.9 43.8 5.5 10.1 9.6 9.6 27.2 10.4 33.6 26.5 10.8 146.9 113.2 32.4 193.2 41.3 32.3 77.0 130.5 111.9 128.4 203.5 74.8 56.3 46.3 101.5 121.3 77.1 85.1 109.1 197.5 74.8 36.0 190.9 269.6 52.0 104.9 423.6 98.8 60.4 100.0 314.9 142.0 264.1 40.1 208.2 57.7 152.7 221.8 54.8 141.7 95.9 297.8 186.0 112.9 243.7 80.3 80.4 197.4 49.3 22.3 281.6 200.8 26.1 78.8 534.8 20.3 105.8 192.2 105.2 76.1 167.1 179.9 137.8 185.1 121.6 72.1 173.4 213.4 169.1 51.1 416.3 258.3 27.9 336.6 27.3 130.7 32.8 30.9 335.0 103.3 26.2 26.0 39.4 35.0 268.3 242.6 66.0 258.3 7.7 8.0 8.0 10.9 8.0 9.8 9.8 8.5 9.8 8.5 10.1 10.8 23.6 9.6 8.3 1.6 25.2 74.4 42.4 114.8 51.8 3.6 84.8 72.8 41.7 57.2 97.3 20.2 2.1 41.3 27.3 70.1 29.4 226.1 17.0 11.6 39.0 54.6 40.2 79.9 0.8 730.0 224.2 68.6 35.7 12.5 18.4 76.0 65.3 103.4 223.4 0.0 1.3 138.2 79.3 108.6 82.2 106.2 43.5 83.9 72.9 1.9 101.9 19.2 21.6 4.0 0.4 277.9 64.5 19.2 38.7 100.2 19.5 103.1 33.5 2.2 13.1 17.6 85.2 1.9 25.5 209.3 85.4 38.6 19.8 69.3 83.8 58.9 EIF4EBP2 ENSG00000148730 "Eukaryotic translation initiation factor 4E binding protein 2" Q13542 10 70404145-70428618 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019415, HPA037410, HPA061665" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "CAB019415: AB_10699019, HPA037410: AB_2675461, HPA061665: AB_2684580" "unprognostic (9.57e-2)" "unprognostic (3.22e-2)" "unprognostic (2.27e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-1)" "unprognostic (3.51e-1)" "unprognostic (3.84e-1)" "unprognostic (7.24e-2)" "unprognostic (8.24e-2)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (1.46e-1)" "prognostic favorable (6.69e-6)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (1.53e-1)" "unprognostic (4.61e-2)" 67.7 27.6 27.8 23.2 25.2 30.4 44.8 21.8 23.6 29.0 28.9 41.2 40.4 25.1 16.5 31.9 25.8 23.8 40.8 21.0 23.9 57.3 50.5 30.5 26.2 28.9 26.6 34.9 30.2 27.5 11.2 43.8 21.7 24.7 39.6 34.9 28.2 33.6 64.2 35.0 47.3 27.2 23.6 26.7 30.9 18.2 34.7 34.5 23.2 67.4 29.2 36.2 28.2 20.1 56.3 17.8 93.7 92.0 176.9 66.8 51.8 33.5 40.5 24.0 25.9 77.5 48.1 57.2 20.1 48.6 14.9 35.6 46.2 30.4 26.9 63.6 24.0 41.4 21.1 30.8 41.5 74.4 28.4 74.8 30.8 29.4 26.4 48.4 36.8 46.0 69.0 50.7 37.5 31.5 64.3 76.3 80.7 54.2 31.8 66.3 37.6 37.4 30.7 56.3 51.1 77.6 45.7 103.0 44.5 63.8 47.2 65.3 40.6 15.6 20.0 25.8 30.2 35.5 73.2 66.5 18.1 108.2 16.3 20.8 19.2 28.7 16.4 16.8 13.2 9.0 13.1 13.8 17.2 8.2 10.9 11.4 21.1 11.6 23.0 5.7 15.7 19.2 27.8 25.2 21.8 23.6 21.0 23.9 28.9 26.6 21.7 23.6 34.7 20.1 72.5 25.6 37.6 21.9 31.9 52.9 53.5 25.4 27.9 46.8 42.9 32.5 147.0 68.6 29.1 36.8 20.9 47.3 45.2 196.7 43.0 43.9 25.9 33.1 52.1 41.4 26.5 70.5 13.0 59.3 119.1 49.9 34.7 57.8 11.4 39.0 61.8 157.4 46.0 23.5 17.5 73.6 34.6 95.4 45.1 59.0 65.9 50.9 21.4 24.4 92.9 73.1 76.2 22.1 9.1 59.5 94.7 61.3 33.8 63.4 195.2 137.0 23.4 17.2 78.9 46.4 37.1 43.7 47.1 39.1 70.0 57.3 43.0 47.0 73.1 109.4 EIF5A2 ENSG00000163577 "Eukaryotic translation initiation factor 5A2" Q9GZV4 3 170888418-170908644 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.3" "Group enriched" "Detected in many" 12 "Early spermatids: 353.0;Late spermatids: 977.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029090 Approved Supported Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA029090: AB_10671359" "unprognostic (2.41e-1)" "unprognostic (2.42e-1)" "unprognostic (4.05e-1)" "unprognostic (5.75e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (1.11e-3)" "unprognostic (1.47e-1)" "unprognostic (3.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (2.66e-2)" "unprognostic (3.45e-2)" "unprognostic (5.92e-2)" "unprognostic (1.64e-2)" "unprognostic (4.29e-3)" 4.1 2.7 1.9 3.1 2.8 4.2 2.9 5.8 6.1 3.1 1.9 3.4 1.7 4.5 1.3 2.9 2.4 3.5 4.0 1.9 5.4 5.0 1.6 2.2 2.8 7.2 4.6 4.4 3.3 3.7 1.8 1.8 8.2 2.6 2.6 2.8 1.9 3.0 1.3 1.9 1.6 7.2 4.1 2.3 9.1 28.3 5.5 4.3 2.2 3.1 3.1 3.5 2.0 7.2 22.7 11.6 4.2 5.9 21.7 14.2 10.0 17.1 22.3 17.4 25.1 23.6 14.4 14.2 30.9 23.4 38.9 7.4 13.4 6.0 21.9 15.8 5.8 6.9 4.6 7.5 14.6 18.2 19.9 16.6 8.7 26.3 21.4 24.2 9.1 3.7 5.8 0.1 28.7 7.6 8.1 7.9 8.1 17.5 7.8 0.0 12.0 0.0 7.3 4.0 3.4 6.4 17.7 4.6 14.4 6.5 10.0 11.9 12.0 21.2 15.0 44.8 38.9 21.6 0.3 33.3 7.2 6.2 15.4 14.9 1.4 1.5 12.4 1.5 8.7 2.2 8.4 11.9 1.0 3.5 5.0 8.3 0.7 8.8 1.4 1.0 11.3 5.0 1.9 2.8 5.8 6.1 1.9 5.4 7.2 4.6 8.2 4.1 5.5 7.2 16.6 0.0 0.5 4.9 4.4 17.1 8.5 7.8 10.8 2.5 2.1 2.7 9.5 0.0 1.8 1.8 0.0 1.2 18.1 1.6 1.9 6.4 353.0 0.9 7.7 12.8 4.9 2.1 7.1 7.5 1.9 11.7 8.6 0.6 2.5 2.6 3.3 2.5 8.9 0.0 8.8 0.8 2.0 3.8 7.2 977.9 12.8 4.5 10.6 3.7 7.9 8.0 28.8 4.0 10.1 19.6 6.1 11.3 3.7 8.2 1.7 21.1 3.4 2.7 46.0 9.6 11.6 54.3 10.0 2.3 21.6 0.7 15.7 2.2 1.8 5.7 ELF4 "ELFR, MEF" ENSG00000102034 "E74 like ETS transcription factor 4" Q99607 X 130063955-130110716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 34.3;Granulosa cells: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058595, HPA060277" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" Nucleoplasm "HPA058595: AB_2683768, HPA060277: AB_2684239" "unprognostic (1.33e-1)" "unprognostic (8.51e-2)" "unprognostic (3.83e-1)" "unprognostic (2.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (4.43e-3)" "unprognostic (7.86e-3)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.29e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (6.49e-6)" "unprognostic (1.43e-1)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "prognostic favorable (1.42e-4)" 12.2 3.7 1.8 14.6 1.6 53.1 9.6 2.8 2.0 9.4 2.6 18.1 14.2 10.6 2.0 11.7 12.1 9.3 5.6 1.8 2.4 6.0 2.8 15.9 18.3 2.8 2.4 17.5 2.6 4.8 4.2 23.7 2.4 6.1 17.7 0.6 5.5 4.1 2.0 10.9 17.0 10.6 1.5 18.1 20.3 2.6 2.9 19.6 3.9 3.6 18.0 18.8 9.1 3.1 56.0 20.7 3.7 0.4 9.1 19.3 52.6 25.3 32.1 30.4 33.4 28.7 38.9 28.6 49.5 34.8 42.3 35.2 20.5 30.0 29.9 31.0 16.8 56.7 27.3 13.6 20.2 49.7 69.3 20.4 32.6 49.1 48.0 19.0 30.0 6.5 22.0 7.7 16.5 32.8 8.2 28.2 2.4 28.4 19.4 17.6 6.5 12.2 18.3 63.9 13.6 6.0 22.8 21.9 6.9 19.1 11.0 46.9 27.6 21.2 16.6 39.5 47.7 4.2 1.8 22.6 24.6 44.8 5.0 1.6 4.0 5.8 7.1 7.6 5.6 2.6 4.2 6.1 4.5 2.7 4.2 4.8 6.9 6.5 5.5 2.7 4.8 4.2 1.8 1.6 2.8 2.0 1.8 2.4 2.8 2.4 2.4 1.5 2.9 3.1 10.7 9.6 4.4 0.0 8.0 13.6 8.2 2.9 9.1 0.0 2.1 1.5 0.8 0.0 4.4 0.0 0.0 10.6 12.2 24.1 0.0 2.3 0.1 8.9 3.8 8.4 9.0 7.4 0.2 4.0 34.3 6.4 17.9 17.1 1.3 27.5 6.4 1.0 9.7 0.0 0.3 8.3 2.0 12.2 9.2 0.6 1.8 14.8 3.6 5.6 13.1 0.0 16.5 0.0 1.2 9.1 17.4 1.2 2.0 7.5 11.6 0.3 5.4 0.0 6.6 2.6 2.5 0.0 4.0 6.5 10.4 11.2 9.5 5.2 7.1 18.9 ELMO1 "CED-12, CED12, ELMO-1, KIAA0281" ENSG00000155849 "Engulfment and cell motility 1" Q92556 7 36852906-37449223 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 228.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 236.7;Microglial cells: 519.0;Oligodendrocyte precursor cells: 284.0;Oligodendrocytes: 1412.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 129.9;JURKAT: 122.0;Karpas-707: 118.0;U-698: 141.7;U-937: 123.4" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.77e-2)" "unprognostic (8.29e-3)" "unprognostic (1.55e-1)" "unprognostic (1.19e-2)" "unprognostic (3.69e-1)" "unprognostic (4.09e-2)" "unprognostic (3.01e-2)" "unprognostic (3.53e-3)" "unprognostic (1.34e-1)" "unprognostic (1.71e-1)" "prognostic favorable (4.62e-4)" "unprognostic (3.59e-1)" "prognostic unfavorable (3.27e-5)" "unprognostic (1.65e-2)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (3.16e-3)" 27.5 14.5 77.5 32.4 131.5 59.4 21.9 95.1 108.2 14.9 24.3 11.8 6.6 7.8 4.5 10.9 10.4 21.2 16.6 82.9 88.5 6.9 28.0 28.9 49.2 131.7 108.9 13.4 13.2 4.9 12.0 38.1 124.2 10.8 13.0 12.9 9.4 9.9 7.2 10.1 19.1 15.9 89.5 56.4 9.0 6.5 126.1 29.4 82.0 16.6 51.4 18.7 15.5 228.3 0.2 4.1 7.6 0.0 0.0 0.0 16.4 0.2 0.1 0.0 0.0 0.2 0.0 129.9 2.2 0.0 1.0 0.5 0.0 0.0 0.0 72.7 4.7 94.6 0.3 0.0 0.0 60.5 38.0 1.6 0.0 0.0 0.0 0.0 49.8 122.0 1.5 118.0 0.0 0.8 69.8 84.0 19.4 0.2 0.0 77.5 10.1 72.3 0.2 0.0 8.5 40.3 0.3 24.1 0.5 27.3 0.1 43.3 14.4 0.2 1.4 0.3 0.6 98.8 90.1 141.7 21.1 123.4 6.0 49.9 52.8 164.1 33.2 45.7 33.8 49.8 52.1 36.6 78.2 39.7 47.1 36.3 107.0 41.6 40.6 40.1 47.8 55.6 77.5 131.5 95.1 108.2 82.9 88.5 131.7 108.9 124.2 89.5 126.1 228.3 60.4 0.0 4.8 10.4 53.3 5.0 4.5 0.0 3.4 13.7 2.0 2.8 3.5 7.2 0.6 0.0 0.0 1.5 26.8 0.4 0.0 0.2 1.0 1.8 2.4 44.6 3.6 24.6 236.7 1.1 26.7 14.6 0.0 1.1 34.9 6.9 37.1 15.4 20.4 0.0 106.7 0.9 0.0 50.7 58.3 1.5 6.2 44.8 7.2 519.0 34.6 1.1 41.2 284.0 1412.3 0.6 0.8 24.8 31.7 1.9 0.0 2.0 0.0 1.8 13.1 9.5 2.7 1.4 4.6 0.8 4.3 19.7 35.6 15.2 0.2 1.8 ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Paneth cells: 50.3;Proximal enterocytes: 100.3;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.1;CAPAN-2: 49.3;HaCaT: 46.9;T-47d: 45.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "HPA021484: AB_1848129" "unprognostic (4.49e-3)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.16e-3)" "unprognostic (3.14e-1)" "unprognostic (8.17e-3)" "unprognostic (1.73e-1)" "unprognostic (8.06e-2)" "unprognostic (3.40e-2)" "unprognostic (6.95e-3)" "prognostic favorable (2.77e-5)" "unprognostic (3.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (1.97e-2)" 2.8 1.8 1.5 4.3 1.4 5.6 8.8 2.4 2.6 6.4 0.3 24.3 33.1 2.0 4.1 25.8 8.5 8.6 1.9 1.1 1.7 21.4 8.1 8.3 2.9 2.1 1.0 1.8 41.0 8.5 29.8 7.1 2.8 19.3 9.1 0.7 20.3 9.6 1.2 33.5 26.3 0.8 0.4 5.6 26.0 13.0 1.3 2.1 19.3 0.3 2.6 8.5 13.2 1.5 22.1 2.5 2.4 3.0 0.4 0.6 33.1 1.3 0.7 1.6 1.4 14.2 49.3 3.0 1.5 0.7 0.7 46.9 2.2 21.6 0.3 1.4 2.9 3.2 4.8 4.7 1.0 1.9 7.5 0.5 15.6 1.2 1.1 1.6 1.7 2.6 3.1 1.5 0.9 18.4 2.0 9.3 3.2 20.7 1.9 4.6 2.3 4.9 2.0 2.9 16.2 3.6 3.2 14.4 1.5 1.3 45.8 3.4 2.8 3.7 4.5 2.3 2.3 4.9 1.7 5.8 1.9 4.4 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 1.5 1.4 2.4 2.6 1.1 1.7 2.1 1.0 2.8 0.4 1.3 1.5 1.8 0.0 13.1 0.0 2.0 8.8 11.9 21.9 13.1 0.9 20.6 16.3 1.2 15.7 12.6 20.2 0.0 33.8 1.0 63.9 17.6 20.1 22.9 8.8 1.7 1.6 13.1 6.9 0.4 24.0 15.0 1.7 47.4 12.2 4.5 1.3 1.4 3.6 3.6 0.0 0.3 33.8 22.4 1.6 3.1 36.3 0.9 2.6 3.6 1.9 2.8 0.4 0.0 0.0 1.0 24.8 50.3 0.7 1.4 7.9 100.3 28.6 12.3 1.5 0.0 0.4 1.6 14.5 5.9 14.4 13.5 16.8 2.3 5.0 52.3 13.0 ELMOD3 "DFNB88, FLJ21977, RBED1, RBM29" ENSG00000115459 "ELMO domain containing 3" Q96FG2 2 85354394-85391752 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012126 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA012126: AB_1848130" "unprognostic (1.90e-1)" "unprognostic (9.80e-3)" "unprognostic (1.42e-3)" "unprognostic (1.76e-1)" "unprognostic (3.24e-1)" "unprognostic (1.60e-2)" "unprognostic (1.35e-2)" "unprognostic (1.52e-2)" "unprognostic (4.62e-2)" "unprognostic (5.63e-2)" "prognostic favorable (6.16e-6)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.09e-6)" "unprognostic (5.71e-2)" "unprognostic (1.53e-1)" "unprognostic (9.51e-2)" "prognostic favorable (2.85e-5)" 11.1 8.2 7.0 3.7 7.4 2.7 8.7 6.6 8.0 7.2 5.1 7.6 4.9 5.6 5.9 5.0 6.9 6.1 5.3 5.9 6.4 6.0 8.8 4.9 5.4 6.9 6.8 6.5 6.0 8.9 6.6 6.1 6.2 8.4 4.9 3.1 6.2 7.0 12.1 5.1 5.6 6.7 6.4 6.6 7.1 2.7 6.7 5.4 6.3 10.2 5.0 7.3 6.3 7.0 4.9 6.0 6.7 10.0 20.9 9.2 4.0 8.6 6.7 12.6 11.7 5.0 2.4 3.7 6.7 7.2 15.9 5.1 9.7 11.9 11.4 13.0 6.7 6.5 3.4 3.7 10.9 4.9 8.2 9.6 10.6 12.1 13.6 10.6 9.1 7.4 6.6 4.2 11.9 3.9 7.2 2.9 3.3 9.8 6.4 5.2 13.9 3.5 5.8 3.0 6.3 3.3 5.3 7.3 7.9 7.6 4.0 3.5 4.8 9.1 4.9 7.9 8.0 5.0 9.9 4.9 9.1 5.7 9.4 6.5 2.7 8.0 5.0 1.9 2.7 3.1 3.2 2.0 3.2 2.6 2.7 4.8 2.5 5.0 4.5 0.9 5.5 2.8 7.0 7.4 6.6 8.0 5.9 6.4 6.9 6.8 6.2 6.4 6.7 7.0 9.0 6.4 8.4 36.9 15.7 4.7 10.0 13.0 8.6 27.2 10.7 7.6 5.2 10.0 16.7 11.0 29.2 15.2 9.8 17.3 7.9 8.6 5.6 4.6 6.9 9.5 8.4 7.4 24.3 9.1 5.9 10.0 12.8 4.0 8.9 20.7 12.5 7.5 8.6 30.3 21.4 11.4 14.2 10.0 9.3 5.6 19.3 9.5 17.8 18.7 16.5 14.1 28.8 28.6 49.7 10.4 15.3 23.7 7.7 10.8 24.9 7.1 11.7 30.9 19.7 10.0 8.0 19.7 10.9 6.7 6.5 12.4 14.0 18.3 12.7 9.4 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 78.5 54.7 77.2 39.8 115.6 52.9 66.6 121.1 116.9 57.1 61.4 63.9 51.6 46.5 30.6 176.6 38.9 42.4 47.2 76.8 93.2 59.7 45.8 59.6 40.1 152.0 110.1 28.9 55.4 46.2 27.2 51.0 140.7 58.7 48.6 8.4 72.7 48.8 24.1 201.9 55.4 50.8 114.8 57.1 70.6 18.6 107.7 22.2 66.8 28.0 55.7 68.5 86.8 165.7 108.0 119.5 22.6 44.8 148.4 138.2 70.2 125.2 154.5 153.5 122.4 105.9 182.5 73.9 94.3 193.6 130.3 119.4 79.7 152.2 93.2 94.6 53.9 96.6 77.3 77.1 128.2 84.2 98.0 106.2 168.2 180.9 198.4 114.8 155.0 27.7 68.1 54.8 178.5 79.5 19.9 69.5 33.5 136.9 120.2 43.6 59.9 89.7 195.5 128.7 27.4 28.8 73.7 258.4 105.8 66.8 121.2 82.4 132.2 129.7 82.5 161.2 161.3 26.6 31.2 35.4 127.8 85.2 120.1 134.9 189.6 172.7 105.1 180.0 93.4 109.0 98.4 103.2 212.8 94.2 63.5 88.0 133.0 114.7 179.6 148.8 113.8 203.1 77.2 115.6 121.1 116.9 76.8 93.2 152.0 110.1 140.7 114.8 107.7 165.7 44.0 19.2 12.5 7.5 28.1 15.6 25.9 61.1 29.6 5.7 60.3 37.5 4.7 34.3 40.2 40.5 10.4 93.4 36.0 114.0 7.9 91.5 3.4 22.9 26.3 43.6 19.2 67.8 3.8 100.1 127.4 26.1 48.4 45.2 21.0 52.6 24.7 16.7 74.9 3.3 3.4 33.8 46.8 46.3 37.5 4.6 20.2 41.5 12.4 7.5 92.5 13.7 32.0 3.0 66.1 133.3 63.9 25.6 19.0 44.7 66.0 23.3 14.5 9.5 19.7 10.0 39.7 8.4 11.2 70.1 31.0 95.9 31.5 50.8 47.2 49.2 ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226299-102229589 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 30.5" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Breast myoepithelial cells: 3.2;Skeletal myocytes: 5.0;Spermatogonia: 3.4;Theca cells: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "classical monocyte: 7.1;intermediate monocyte: 2.4;myeloid DC: 2.0;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 10 "dendritic cells: 2.0;monocytes: 7.1" "Cell line enhanced" "Detected in many" "ASC diff: 9.5;ASC TERT1: 9.4;HSkMC: 13.9;NB-4: 11.6;SiHa: 22.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA036236 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" 3.2 0.7 1.0 0.3 0.8 1.8 3.5 0.5 1.3 0.1 0.3 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.2 1.0 0.4 0.8 0.0 1.0 0.1 0.4 0.9 0.1 0.0 0.1 0.0 0.9 0.4 0.2 0.1 0.1 0.3 0.1 0.2 30.5 0.2 0.0 0.4 0.8 0.1 1.2 0.4 0.0 0.0 0.3 0.0 0.2 0.3 0.5 3.2 0.2 0.2 7.8 9.5 9.4 2.8 0.1 0.3 0.4 0.5 0.5 3.0 0.0 0.3 0.0 0.0 0.1 5.9 0.1 0.5 0.0 0.0 0.2 0.4 0.8 0.3 0.0 0.1 13.9 1.6 3.6 0.0 0.0 0.0 0.9 0.1 3.5 0.8 0.0 0.0 11.6 0.1 1.1 1.0 0.0 5.1 0.0 2.0 0.1 0.0 0.4 22.6 0.9 0.7 0.6 8.1 2.7 0.0 1.5 0.0 0.3 0.3 0.5 7.2 0.0 3.4 6.5 0.0 0.0 7.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 5.9 0.0 0.0 1.7 1.0 0.8 0.5 1.3 1.0 0.4 0.4 0.9 0.4 0.4 0.4 0.5 2.5 0.0 1.1 0.0 0.2 0.4 0.5 0.6 0.6 0.0 1.1 3.2 0.3 0.0 0.5 0.0 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 1.3 1.9 0.0 0.0 0.3 0.0 0.7 1.3 0.0 0.2 0.0 0.0 1.4 0.4 0.2 0.0 0.0 0.2 0.0 1.5 0.8 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 5.0 1.2 0.1 3.4 0.6 0.1 0.3 0.3 2.2 0.2 0.1 EMC3 TMEM111 ENSG00000125037 "ER membrane protein complex subunit 3" Q9P0I2 3 9962537-10011116 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 360.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042372 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "HPA042372: AB_10795609" "unprognostic (1.31e-1)" "unprognostic (2.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.02e-2)" "unprognostic (1.59e-3)" "unprognostic (2.90e-2)" "unprognostic (2.05e-3)" "unprognostic (2.46e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-1)" "prognostic favorable (2.81e-6)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.71e-2)" "unprognostic (5.58e-2)" 71.1 41.1 26.5 28.9 27.6 65.7 33.3 28.5 29.9 26.1 29.7 40.6 37.4 23.2 26.9 46.1 28.9 27.9 34.3 29.2 29.4 40.3 65.7 36.1 22.7 31.0 29.5 22.5 43.6 70.5 17.2 20.3 30.4 25.8 36.0 24.2 42.8 32.0 78.5 33.6 37.3 32.0 28.3 23.1 35.3 48.5 28.8 27.2 39.9 46.7 28.5 40.7 25.1 30.4 48.9 100.7 37.4 22.5 232.6 90.3 125.1 98.1 84.6 60.1 64.8 69.5 75.6 38.7 69.8 111.9 115.2 66.7 64.2 58.3 61.7 105.2 64.3 63.6 69.9 46.5 100.4 71.8 68.2 107.4 102.5 104.9 60.1 76.5 75.6 41.8 82.0 109.2 90.2 119.5 38.3 35.6 41.5 103.2 68.7 49.0 52.4 115.7 72.8 86.7 26.4 53.1 69.9 103.3 63.4 39.1 87.5 58.0 87.6 59.8 49.6 65.0 100.8 58.3 165.6 79.0 126.2 52.0 76.4 119.7 115.1 108.5 64.5 93.6 66.8 65.6 63.7 74.5 88.3 71.2 45.8 61.5 103.5 77.3 95.3 79.1 107.3 156.1 26.5 27.6 28.5 29.9 29.2 29.4 31.0 29.5 30.4 28.3 28.8 30.4 59.1 54.5 72.9 19.9 45.3 50.6 59.9 178.0 24.5 40.6 43.0 39.9 108.1 57.2 121.4 46.0 39.6 49.5 52.7 58.6 46.9 100.6 360.7 61.6 50.2 59.2 21.1 240.2 25.4 119.9 51.8 51.1 38.7 64.0 34.1 36.5 46.1 105.0 97.8 23.5 21.1 40.2 109.9 51.0 66.6 109.3 50.4 101.7 58.7 9.4 97.5 65.2 57.7 21.1 17.8 107.4 71.3 37.6 55.6 58.7 92.6 76.9 99.1 63.5 59.2 44.7 60.7 199.7 63.0 49.6 60.7 85.8 52.7 60.6 52.0 80.2 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 ENPEP "CD249, gp160" ENSG00000138792 "Glutamyl aminopeptidase" Q07075 4 110365733-110565285 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 163.6;kidney: 90.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 663.2;Proximal tubular cells: 177.6;Sertoli cells: 157.8" "Cancer enriched" "Detected in many" 8 "renal cancer: 41.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;HEK 293: 7.5;MOLT-4: 1.8;SuSa: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005128 Enhanced NA NA 55000000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "HPA005128: AB_1844795" "unprognostic (2.73e-3)" "unprognostic (2.84e-3)" "unprognostic (5.16e-3)" "unprognostic (3.48e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" "unprognostic (3.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.47e-2)" "unprognostic (4.49e-3)" "unprognostic (3.43e-3)" "unprognostic (1.52e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-3)" 11.6 2.2 0.4 1.5 0.5 0.1 4.8 0.4 2.5 1.6 1.8 1.2 36.6 12.9 4.1 1.7 2.3 4.4 4.3 0.6 0.5 90.0 29.0 4.6 0.8 0.9 0.8 1.2 1.3 45.2 1.2 15.5 0.7 1.8 0.8 0.0 1.1 1.2 2.3 0.7 163.6 10.6 0.5 9.2 1.2 0.5 0.4 4.4 5.0 8.9 0.3 2.6 1.6 0.8 0.0 0.2 0.0 0.0 0.1 0.1 2.7 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.8 0.3 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.1 0.0 1.3 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 2.5 0.6 0.5 0.9 0.8 0.7 0.5 0.4 0.8 10.7 0.0 2.0 1.6 1.1 1.7 0.1 0.0 0.0 0.0 0.2 0.1 3.9 0.0 0.3 11.0 0.0 37.0 0.0 1.5 17.6 0.0 0.5 3.1 40.7 2.2 1.8 0.0 7.3 0.0 3.5 15.4 0.0 2.3 0.0 0.0 1.4 31.4 2.7 0.0 2.9 28.4 2.0 1.0 1.9 0.2 0.6 1.1 0.0 1.0 0.0 0.0 1.0 0.0 0.8 0.0 31.6 0.4 0.1 0.2 663.2 177.6 1.7 0.0 157.8 0.8 54.1 0.0 0.2 0.1 1.0 58.6 1.9 0.5 42.1 0.1 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 ENPP4 "AP3Aase, KIAA0879, NPP4" ENSG00000001561 "Ectonucleotide pyrophosphatase/phosphodiesterase 4" Q9Y6X5 6 46129989-46146688 "Enzymes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Oligodendrocytes: 125.3;Respiratory ciliated cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 21.9;U-266/84: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016594 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA016594: AB_1848171" "unprognostic (9.87e-2)" "unprognostic (1.74e-1)" "unprognostic (2.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (8.13e-2)" "unprognostic (5.51e-3)" "unprognostic (1.98e-1)" "unprognostic (1.26e-1)" "unprognostic (8.51e-2)" "unprognostic (4.36e-1)" "prognostic favorable (6.95e-7)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-2)" "unprognostic (2.56e-1)" 15.1 13.6 11.7 7.3 20.9 38.0 7.8 19.5 19.5 10.3 6.4 12.1 10.9 4.0 11.6 5.1 10.8 8.0 15.1 10.8 16.0 18.4 8.2 20.7 7.7 20.5 19.3 2.1 11.9 22.3 9.0 3.5 19.9 16.4 12.8 12.2 21.3 19.7 22.1 2.3 10.1 7.0 18.5 13.9 14.8 8.3 17.5 8.5 12.5 25.3 6.5 6.8 2.1 30.2 0.1 1.1 0.7 1.5 0.0 0.0 0.1 1.7 1.6 4.0 0.3 1.9 13.4 15.2 12.7 2.1 9.9 0.2 4.1 0.6 0.8 18.5 11.1 8.5 0.0 0.0 0.5 10.5 14.9 2.1 0.0 0.1 0.0 1.1 1.4 10.5 0.0 0.0 1.5 1.8 7.8 1.0 2.7 16.9 0.5 5.9 2.7 5.7 8.3 1.7 18.0 0.0 0.0 2.8 0.0 4.1 7.6 4.3 0.0 0.0 6.7 0.3 11.2 21.9 26.6 5.2 10.3 0.0 1.4 0.0 0.4 0.9 9.2 1.1 5.4 2.8 3.4 6.8 1.5 1.2 3.2 5.8 0.3 4.4 2.6 1.6 1.2 3.0 11.7 20.9 19.5 19.5 10.8 16.0 20.5 19.3 19.9 18.5 17.5 30.2 43.5 76.9 27.0 23.5 11.6 0.9 3.2 2.3 0.6 9.3 11.0 2.4 23.1 14.3 25.4 29.5 14.6 0.5 23.5 27.2 0.0 12.9 18.3 28.8 2.0 16.0 15.7 3.0 26.4 12.2 0.3 8.5 10.7 17.3 15.8 4.5 6.1 8.6 5.8 26.9 19.2 13.8 4.1 24.8 11.0 26.0 1.2 19.0 3.6 6.5 15.2 21.6 34.0 32.2 125.3 9.7 16.1 11.3 10.3 12.6 16.3 12.6 70.6 6.2 0.0 22.1 5.4 9.1 9.8 0.3 0.6 0.3 14.7 3.7 11.3 14.8 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 107.2;kidney: 95.2;liver: 263.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 209.3;Hepatocytes: 134.8;Intestinal goblet cells: 77.1;Proximal enterocytes: 87.0" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.3" "Cell line enhanced" "Detected in all" "RT4: 57.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" NA NA 5900000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 8.2 7.7 5.0 11.4 7.3 8.0 12.4 7.1 6.7 7.3 7.1 94.6 72.1 6.3 7.7 11.3 5.7 12.1 7.7 5.1 6.3 95.2 263.7 6.5 5.5 7.6 7.3 6.7 4.9 7.7 5.0 5.6 7.8 37.7 107.2 9.4 10.7 4.4 15.0 8.1 68.4 9.7 6.5 6.0 42.3 8.6 7.3 4.6 6.1 9.1 5.6 16.9 7.2 9.0 9.5 7.8 8.2 15.1 16.5 15.5 9.4 9.6 7.9 6.4 7.1 5.6 10.9 10.6 4.7 12.8 6.0 10.8 8.5 14.1 7.2 8.8 4.0 7.9 5.7 30.9 15.5 4.7 8.8 12.9 14.0 8.7 18.2 8.8 13.1 17.1 8.8 15.4 9.7 13.6 5.4 5.6 2.5 8.5 15.7 6.0 8.0 5.2 11.4 57.1 5.8 6.0 16.6 12.9 9.2 6.4 18.7 4.1 10.8 12.6 12.7 7.5 7.2 10.1 16.9 8.3 8.0 8.8 11.5 18.3 1.2 9.4 2.5 2.3 1.3 1.4 1.3 1.8 1.7 1.5 2.1 2.1 0.1 0.5 1.4 0.9 1.6 1.3 5.0 7.3 7.1 6.7 5.1 6.3 7.6 7.3 7.8 6.5 7.3 9.0 8.0 16.0 6.7 8.1 4.9 3.7 6.2 8.9 5.2 6.6 15.0 7.9 5.2 10.0 11.3 7.3 4.2 8.2 4.3 209.3 25.4 6.9 19.5 10.0 13.6 7.0 16.2 36.6 5.9 12.9 6.7 7.9 23.0 25.8 1.3 9.6 9.7 134.8 6.2 10.1 8.2 77.1 14.2 9.7 1.9 12.7 2.8 5.2 5.4 11.2 5.4 4.9 8.2 2.0 11.3 9.1 58.4 5.7 3.6 28.5 87.0 63.1 6.4 12.2 13.1 6.0 5.9 27.2 19.1 8.5 3.4 3.3 4.9 10.3 60.9 39.0 EOMES TBR2 ENSG00000163508 Eomesodermin O95936 3 27715949-27722711 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Differentiation, Gastrulation, Immunity, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.4;lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "dendritic cells: 43.6;Erythroid cells: 16.8;NK-cells: 93.7;T-cells: 31.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Region enriched" "Detected in single" 13 "cerebellum: 8.4" "Group enriched" "Detected in many" 7 "gdT-cell: 16.5;MAIT T-cell: 26.2;memory CD8 T-cell: 19.5;naive CD8 T-cell: 11.9;NK-cell: 33.0" "Group enriched" "Detected in many" 107 "NK-cells: 33.0;T-cells: 26.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.4;JURKAT: 8.3;SCLC-21H: 3.9" "Region enriched" "Detected in many" 8 "olfactory bulb: 77.5" "Group enriched" "Detected in some" 27 "cerebellum: 30.2;olfactory bulb: 12.7" HPA028896 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA028896: AB_10601370" "unprognostic (1.53e-4)" "unprognostic (5.95e-3)" "unprognostic (3.01e-2)" "unprognostic (1.60e-4)" "unprognostic (4.13e-2)" "unprognostic (9.63e-4)" "unprognostic (4.29e-4)" "unprognostic (3.14e-3)" "unprognostic (1.24e-1)" "unprognostic (2.82e-2)" "unprognostic (9.96e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (6.32e-3)" "unprognostic (1.49e-2)" 1.0 0.6 0.2 3.2 0.1 1.8 0.6 8.4 0.4 0.4 0.4 0.7 0.4 0.8 0.8 0.3 0.4 1.6 0.3 0.2 0.3 0.4 2.4 2.2 15.0 0.2 0.3 0.5 0.3 0.1 0.2 0.4 0.6 0.5 0.8 1.6 0.9 0.1 0.1 0.2 1.4 0.4 0.3 12.8 1.3 0.4 0.2 1.5 0.5 0.1 5.4 1.3 0.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.6 1.3 0.0 7.4 1.1 0.0 0.0 0.5 0.0 0.9 0.0 0.0 0.8 0.0 0.9 0.3 0.0 8.3 0.2 0.0 0.0 2.0 2.0 0.0 0.2 0.2 0.9 1.3 0.0 0.0 0.6 0.0 3.9 0.0 0.0 0.0 0.9 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 16.5 0.0 26.2 0.0 3.0 19.5 0.0 0.0 0.2 11.9 0.2 33.0 0.1 0.1 0.0 2.9 0.2 0.1 8.4 0.4 0.2 0.3 0.2 0.3 0.6 0.3 0.2 0.4 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.8 1.5 0.0 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 16.8 0.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 2.2 1.6 0.2 0.0 0.0 0.0 0.0 3.1 0.7 0.0 0.3 1.3 1.8 1.0 1.1 0.1 93.7 0.0 0.0 0.0 0.0 0.4 9.8 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 2.0 0.0 0.1 0.0 31.5 0.0 0.0 0.0 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 64.3;Oligodendrocyte precursor cells: 164.4;Oligodendrocytes: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 30.1;HeLa: 36.5;RT4: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Nucleoplasm "HPA036580: AB_10669908" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.92e-3)" "unprognostic (3.64e-2)" "unprognostic (4.73e-2)" "unprognostic (5.59e-3)" "unprognostic (4.40e-2)" "unprognostic (8.38e-2)" "unprognostic (1.90e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.65e-5)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" 8.7 4.5 4.8 3.2 5.7 3.6 5.3 4.1 4.8 4.1 9.0 4.0 2.6 4.3 12.7 10.1 7.4 13.8 9.2 6.0 5.1 11.7 3.3 7.7 3.3 5.7 4.6 5.7 4.9 8.0 0.5 9.3 4.8 5.8 4.8 16.0 7.2 5.4 4.2 8.8 3.4 2.7 4.9 4.7 5.6 6.1 4.8 3.6 13.5 4.2 3.6 5.1 2.3 4.8 0.8 5.5 14.3 1.5 0.0 0.0 2.9 2.1 0.0 0.0 0.0 3.0 12.3 6.2 30.1 0.0 0.8 7.4 1.1 6.9 0.0 1.0 5.0 9.8 36.5 2.0 0.1 2.6 3.1 0.0 3.0 0.0 0.0 1.6 9.2 1.7 1.9 5.6 0.0 1.8 4.6 3.5 2.7 1.2 1.1 2.3 10.7 1.3 8.4 21.6 11.8 6.1 10.7 5.2 4.5 9.8 15.9 1.4 15.7 0.7 2.4 1.9 4.4 5.6 1.3 4.6 1.4 5.2 0.8 0.5 0.2 0.1 2.0 0.3 1.1 1.4 0.6 0.6 0.2 1.6 0.9 1.8 0.2 0.1 0.5 0.1 0.6 0.5 4.8 5.7 4.1 4.8 6.0 5.1 5.7 4.6 4.8 4.9 4.8 4.8 55.9 28.9 7.7 17.3 4.7 6.0 16.8 11.2 13.6 5.0 11.2 4.7 8.3 64.3 24.2 14.7 4.2 7.4 4.5 8.5 11.7 15.0 20.8 19.7 3.1 35.2 1.2 2.1 28.6 7.5 0.7 8.4 7.1 17.1 8.8 11.9 34.6 1.7 2.7 1.7 31.8 6.3 16.2 4.6 2.1 23.0 1.8 1.8 3.6 56.2 3.2 8.2 14.4 164.4 65.4 14.1 10.9 1.9 6.5 13.7 1.9 30.4 39.5 32.1 0.0 8.7 6.0 1.8 9.1 16.0 8.1 2.5 3.7 2.2 7.5 19.1 EPB42 "MGC116735, MGC116737, PA" ENSG00000166947 "Erythrocyte membrane protein band 4.2" P16452 15 43197227-43221018 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape, Erythrocyte maturation" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 98.9" "Cell type enriched" "Detected in many" 33 "Erythroid cells: 480.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 91 "HEL: 85.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040261 Supported Uncertain Nucleoplasm,Cytosol NA NA 1400000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "HPA040261: AB_10673441" "unprognostic (8.45e-2)" "unprognostic (4.66e-1)" "unprognostic (4.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.99e-1)" "unprognostic (1.54e-1)" "unprognostic (1.59e-3)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" "unprognostic (5.27e-3)" "unprognostic (1.31e-1)" "unprognostic (1.48e-5)" "unprognostic (1.70e-2)" "unprognostic (1.20e-1)" "unprognostic (5.88e-2)" "unprognostic (3.47e-3)" 3.1 0.0 0.0 0.0 0.0 98.9 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 2.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 1.9 1.5 0.5 0.0 4.0 0.0 0.0 0.6 1.5 0.5 0.0 6.2 4.5 0.0 1.5 0.0 0.0 14.4 0.0 0.0 1.2 0.0 480.0 0.1 0.0 2.3 0.8 0.0 0.0 4.5 0.0 2.5 1.1 1.1 6.7 0.1 0.9 4.1 2.2 2.8 10.5 2.8 1.1 1.8 0.0 3.6 2.5 14.4 0.0 0.0 0.0 1.7 0.7 0.4 1.5 2.4 0.0 0.6 8.4 6.6 1.0 1.0 13.5 4.6 0.0 2.8 6.7 3.8 0.0 0.8 2.0 EPDR1 "EPDR, MERP-1, MERP1, UCC1" ENSG00000086289 "Ependymin related 1" Q9UM22 7 37683843-37951936 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.5;Peritubular cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-937: 122.2;WM-115: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026298, HPA072321" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB026298: AB_425991, HPA072321: " "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (4.44e-3)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic unfavorable (6.97e-4)" "unprognostic (2.53e-2)" "unprognostic (2.75e-1)" "unprognostic (3.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.85e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (4.13e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.00e-4)" 23.1 40.3 46.3 4.2 41.4 4.5 11.3 38.4 82.3 38.5 27.3 10.5 13.4 41.7 13.6 8.4 28.1 10.1 27.4 45.4 67.5 16.4 10.9 27.1 4.9 81.9 50.4 34.0 9.4 8.0 9.4 4.9 83.2 34.5 8.4 14.3 13.8 41.0 122.9 3.2 13.2 29.9 50.9 17.2 5.7 13.0 58.5 11.4 31.0 72.1 3.0 8.8 17.0 38.9 0.2 77.9 6.4 0.1 57.9 20.8 0.1 5.9 0.0 3.0 9.1 7.7 5.1 0.0 84.2 86.0 88.7 0.2 1.8 0.7 0.0 0.1 9.8 34.9 10.2 49.5 0.5 29.1 0.2 35.1 0.0 21.1 0.4 20.0 0.0 34.3 0.0 25.2 51.6 5.1 11.3 25.1 24.0 0.0 11.6 35.2 22.3 30.6 47.3 19.3 8.4 29.3 0.0 3.8 28.2 15.3 0.1 20.4 0.0 16.6 27.8 46.6 36.7 33.8 15.4 0.5 75.5 122.2 114.7 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.4 0.0 0.8 0.0 2.2 0.0 0.1 46.3 41.4 38.4 82.3 45.4 67.5 81.9 50.4 83.2 50.9 58.5 38.9 6.4 32.1 46.2 12.7 1.4 1.3 7.8 3.5 1.2 5.7 1.1 10.5 20.7 7.2 12.7 1.8 0.0 0.5 6.8 5.1 17.6 10.0 0.3 5.5 31.8 2.4 3.6 25.6 36.9 8.0 0.2 15.0 1.5 5.9 2.5 95.5 7.5 10.7 3.1 11.8 39.3 5.1 0.0 1.6 2.0 2.1 28.3 3.1 28.4 14.0 14.2 13.3 2.1 24.6 13.0 19.7 6.9 98.9 0.2 14.6 19.3 14.8 5.7 7.2 6.6 46.4 23.9 0.3 1.8 0.5 0.3 0.1 1.2 28.7 6.4 2.6 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Cell type enhanced" "Detected in many" "Astrocytes: 198.8;dendritic cells: 53.7;Early spermatids: 42.2;Excitatory neurons: 47.9;Inhibitory neurons: 44.3;Late spermatids: 41.2;Oligodendrocyte precursor cells: 77.9" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "neutrophil: 24.0;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 33 "dendritic cells: 23.3;granulocytes: 24.0" "Group enriched" "Detected in some" 5 "HDLM-2: 63.9;HMC-1: 35.5;RPTEC TERT1: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 1.0 0.6 4.7 0.8 18.7 0.7 3.2 40.6 12.8 1.8 0.0 3.2 1.4 2.2 0.9 1.9 1.3 1.7 0.3 7.0 5.1 1.3 1.6 0.3 1.9 5.0 14.4 0.7 0.3 0.2 1.0 0.2 5.5 1.7 0.5 4.2 2.2 2.7 4.9 4.8 0.7 0.7 0.9 1.9 0.6 10.8 12.0 0.7 7.0 10.3 1.7 1.5 1.0 4.2 0.0 0.0 8.4 0.1 0.2 0.0 0.0 6.6 0.1 0.3 0.1 0.1 0.0 1.1 1.6 3.4 0.6 0.1 5.5 0.0 1.2 63.9 0.8 4.8 0.0 0.0 0.0 0.0 35.5 0.1 0.0 0.1 0.0 0.3 0.2 0.5 0.0 0.3 4.7 0.2 0.0 0.3 2.4 1.2 0.1 0.0 0.9 0.2 16.5 0.0 1.1 0.2 0.0 0.1 0.0 1.1 0.1 0.7 0.5 1.1 3.4 0.7 7.9 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 23.3 0.0 0.2 4.7 18.7 40.6 12.8 7.0 5.1 5.0 14.4 5.5 0.9 12.0 4.2 1.9 0.0 0.0 198.8 1.0 3.7 0.0 0.0 0.0 1.9 0.8 12.3 1.6 0.0 0.0 0.0 10.4 0.0 53.7 0.0 0.0 0.8 42.2 0.1 0.5 2.8 0.0 0.0 47.9 0.4 0.1 0.4 0.0 0.1 0.0 3.3 0.4 7.0 0.4 0.0 44.3 0.0 0.0 0.0 0.8 41.2 0.6 0.8 1.8 8.4 0.1 16.9 0.0 77.9 5.6 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.0 3.3 0.8 0.5 1.6 0.0 5.8 0.0 0.2 3.0 0.3 0.2 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810124-225845563 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1178.6;liver: 1705.1" "Cell type enhanced" "Detected in many" "Granulosa cells: 349.9;Hepatocytes: 757.6;Theca cells: 1042.6" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 1161.8;SiHa: 413.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favorable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 245.8 1178.6 233.5 23.6 252.5 22.7 163.7 239.0 249.3 188.3 345.8 82.0 102.2 108.1 97.6 159.6 153.8 96.5 94.0 221.3 233.7 110.7 1705.1 146.8 39.1 225.3 234.9 329.1 536.1 147.7 105.8 32.9 223.6 113.2 52.5 30.7 143.6 128.1 142.5 71.5 52.8 109.6 210.1 55.7 99.9 74.3 258.4 25.9 171.1 95.6 33.4 135.4 140.4 227.2 32.1 202.3 12.3 108.5 1161.8 120.2 24.3 29.7 49.2 28.1 35.1 38.8 293.6 1.3 128.7 147.3 30.6 38.1 32.7 16.8 12.1 7.8 46.5 21.8 83.5 282.7 129.8 12.9 15.1 109.2 40.0 74.6 6.3 116.5 22.1 13.4 14.5 27.3 50.4 30.3 13.5 31.0 61.6 178.1 79.4 27.8 15.2 92.9 91.1 132.5 98.3 13.0 413.0 192.1 51.3 32.1 131.7 43.5 46.8 41.9 35.4 54.5 59.0 9.1 38.9 4.1 63.5 14.2 59.5 0.0 2.6 0.1 0.2 0.7 0.4 0.1 0.3 0.2 0.6 0.2 0.5 0.3 0.2 0.7 0.3 0.9 0.3 0.8 233.5 252.5 239.0 249.3 221.3 233.7 225.3 234.9 223.6 210.1 258.4 227.2 196.9 0.0 14.0 41.1 5.7 19.6 121.8 244.2 74.0 8.8 29.7 27.4 1.2 102.9 255.5 51.5 29.2 46.6 3.4 34.5 17.6 95.3 10.2 142.9 32.2 82.7 10.8 7.0 3.1 73.0 7.6 175.6 30.5 93.4 5.7 349.9 88.2 757.6 149.1 1.7 5.0 17.5 103.7 30.9 28.7 28.4 311.3 25.8 42.7 23.4 9.6 99.2 0.0 7.1 19.4 45.5 27.2 159.1 9.5 40.4 63.4 128.9 174.3 10.1 223.5 29.3 146.9 4.4 5.1 129.0 17.6 22.8 4.7 1042.6 31.5 108.5 EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620134-15882329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 317.0;Sertoli cells: 401.0;Smooth muscle cells: 313.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 22.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 253.0;HHSteC: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003897 Approved Approved "Golgi apparatus" NA NA 17000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA003897: AB_1848224" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-2)" "unprognostic (5.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (3.33e-7)" "unprognostic (2.68e-1)" "prognostic favorable (1.45e-7)" "unprognostic (7.47e-3)" "unprognostic (7.20e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.79e-2)" 62.3 13.0 12.9 16.1 17.4 0.6 33.7 15.3 14.0 53.9 14.1 49.7 37.6 46.2 47.1 20.5 20.1 56.0 26.4 11.1 17.2 55.8 37.8 29.0 9.4 18.5 20.1 49.2 15.1 21.6 3.5 53.1 19.7 16.4 53.7 39.8 13.4 39.8 13.8 11.9 42.7 53.7 15.5 11.9 32.0 15.6 16.1 4.8 22.8 24.3 5.2 51.7 21.4 20.8 65.0 38.8 37.7 1.4 253.0 177.6 53.1 73.6 59.8 34.5 46.1 33.3 97.3 0.0 2.4 140.4 114.4 16.4 11.3 9.5 52.4 0.2 12.6 5.7 11.2 34.7 218.1 4.4 0.2 159.8 42.8 91.7 115.7 44.6 17.7 0.2 0.1 0.2 169.0 17.5 0.2 2.8 5.2 50.3 30.8 0.0 109.5 0.8 97.7 92.5 3.1 4.9 21.4 12.4 91.5 6.2 34.2 4.3 28.7 54.7 14.3 32.4 30.7 3.6 0.4 0.1 32.1 10.7 160.0 0.0 2.7 0.2 0.2 10.8 0.1 1.3 0.9 0.4 5.5 0.3 1.1 0.5 4.4 1.0 22.2 0.4 0.1 1.7 12.9 17.4 15.3 14.0 11.1 17.2 18.5 20.1 19.7 15.5 16.1 20.8 121.4 12.8 175.9 91.1 11.6 17.0 39.6 32.0 13.6 9.7 28.7 42.8 27.6 87.2 58.3 23.9 66.7 33.0 15.2 317.0 60.7 69.4 67.6 87.4 72.0 61.4 38.3 0.4 2.2 68.9 7.3 73.4 81.1 152.2 6.3 139.4 36.0 36.0 65.8 6.7 31.1 54.5 67.1 54.1 35.6 49.4 134.8 46.2 35.6 148.0 8.6 15.4 0.0 121.2 96.9 97.0 217.8 43.6 5.2 26.9 69.0 114.6 104.8 153.7 401.0 18.1 313.1 10.9 4.2 22.8 13.1 21.1 11.8 40.0 80.0 97.6 EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 188.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 211.4;Paneth cells: 175.3;Proximal enterocytes: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 234.3;BEWO: 220.8;CAPAN-2: 206.6;SK-BR-3: 257.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 9.2" HPA041143 Approved Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041143: AB_10794985" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.87e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (3.25e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-1)" "unprognostic (2.79e-1)" "unprognostic (5.03e-2)" 7.8 11.2 5.2 5.7 4.8 0.0 27.0 8.9 5.5 49.4 4.9 42.7 100.8 11.4 3.5 188.5 19.2 13.3 4.3 4.5 6.8 98.4 101.7 32.4 0.7 10.9 9.2 11.8 43.7 3.8 11.5 17.7 6.2 29.3 15.5 1.0 94.6 15.2 1.3 76.3 105.0 2.9 7.1 1.4 48.1 3.2 7.1 2.0 70.2 0.4 10.9 17.5 80.1 6.5 234.3 68.6 0.2 1.6 2.7 14.4 220.8 20.1 20.3 29.2 12.5 51.4 206.6 0.4 81.6 21.4 5.4 122.4 0.6 117.8 6.4 0.6 5.4 0.0 27.7 94.7 16.3 0.3 0.4 8.1 77.8 8.0 18.7 12.3 0.2 0.1 1.8 1.1 3.2 72.1 0.5 1.3 2.7 71.5 24.0 0.5 0.8 1.8 103.8 55.2 0.8 0.8 75.9 257.5 0.5 14.3 94.9 0.2 1.5 11.2 27.3 7.2 1.6 0.9 1.0 0.8 6.1 0.6 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.1 5.2 4.8 8.9 5.5 4.5 6.8 10.9 9.2 6.2 7.1 7.1 6.5 1.8 141.1 51.8 3.9 11.2 19.8 26.2 48.8 51.8 0.6 39.1 37.0 4.5 57.2 62.4 90.1 0.0 47.9 21.6 211.4 27.4 55.2 1.0 47.3 7.1 4.7 43.8 1.3 3.1 80.0 33.4 11.5 131.0 60.8 7.0 0.4 0.7 59.4 4.7 0.0 3.8 76.8 32.6 2.1 7.8 2.3 18.0 2.7 14.2 2.8 3.1 10.0 16.5 2.0 0.7 83.2 175.3 11.7 7.6 33.6 235.9 108.2 60.9 1.5 0.0 0.9 7.5 1.1 4.8 74.9 24.4 92.5 18.6 0.9 77.2 32.1 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;fallopian tube: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 0.3 0.4 10.0 0.0 13.3 0.0 5.6 10.5 11.5 2.9 0.0 0.1 0.0 0.2 0.0 0.1 11.2 0.0 3.0 9.9 12.7 5.1 0.0 0.8 0.0 4.9 16.9 0.1 0.6 3.1 2.4 0.1 7.6 0.3 0.0 2.0 4.7 1.2 1.5 0.3 0.0 0.0 4.3 0.0 0.4 3.3 8.0 0.0 1.6 1.7 0.0 0.1 0.1 6.1 0.0 0.0 6.9 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 5.1 0.7 0.0 0.3 0.2 0.0 0.0 0.1 3.8 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 5.6 0.3 3.1 0.2 0.0 0.1 0.1 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.3 10.5 11.5 9.9 12.7 4.9 16.9 7.6 4.3 8.0 6.1 0.4 0.0 12.6 2020.2 0.0 0.6 0.9 1.1 0.6 15.9 45.6 17.0 27.2 0.0 10.2 12.9 0.0 0.0 0.2 0.0 5.9 0.5 6.7 25.4 1.0 1.0 0.0 0.0 62.0 0.5 0.2 1.8 0.0 25.8 0.0 5.4 0.0 0.0 0.1 0.0 6091.7 0.0 2.0 0.0 0.3 2.2 1.8 0.3 3.6 96.5 0.0 9.1 0.0 2369.0 1049.9 0.0 0.0 0.4 0.0 1.6 0.0 0.2 28.1 1.9 6.6 4.1 3.0 1.8 2.6 0.2 1.3 0.0 0.2 0.0 0.0 1.2 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 19.5;gallbladder: 17.0;intestine: 28.9;salivary gland: 22.9;stomach 1: 51.9" "Cell type enhanced" "Detected in some" "Club cells: 38.4;Distal enterocytes: 80.2;Gastric mucus-secreting cells: 193.7;Intestinal goblet cells: 143.9;Paneth cells: 37.2;Undifferentiated cells: 70.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 43.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.4 0.1 3.0 0.1 0.0 0.1 0.6 0.4 19.5 0.2 28.9 12.9 0.0 0.0 0.9 0.4 17.0 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 0.2 3.5 23.0 0.0 22.9 0.1 0.0 0.2 12.4 0.9 0.0 0.0 51.9 0.1 0.1 0.0 0.0 0.0 0.0 4.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.4 0.0 0.0 1.1 0.0 0.8 0.0 1.5 6.8 0.0 0.0 0.0 0.0 0.5 20.0 38.4 0.0 0.0 0.5 0.0 80.2 0.0 2.3 0.1 0.5 0.2 0.1 10.8 0.0 0.2 1.9 0.0 0.1 193.7 1.6 4.5 0.1 0.0 0.0 0.1 0.0 0.1 143.9 6.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 33.1 37.2 0.0 0.5 1.3 6.1 0.1 16.9 0.0 0.0 1.7 1.6 0.0 0.2 0.0 0.0 0.1 0.4 0.0 70.9 11.1 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ESRP2 "FLJ21918, RBM35B" ENSG00000103067 "Epithelial splicing regulatory protein 2" Q9H6T0 16 68229033-68238102 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 55.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.3;Gastric mucus-secreting cells: 44.9;Late spermatids: 82.4;Syncytiotrophoblasts: 58.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 55.5;MCF7: 113.2;RT4: 60.4;SK-BR-3: 59.8;T-47d: 90.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040751, HPA048597, HPA048618" Uncertain Enhanced Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA040751: AB_2677115, HPA048597: AB_2680458, HPA048618: AB_2680463" "unprognostic (3.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (3.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.62e-2)" "unprognostic (1.54e-1)" "unprognostic (1.33e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (8.80e-2)" "prognostic favorable (1.30e-6)" "unprognostic (1.24e-1)" "unprognostic (3.16e-1)" "unprognostic (9.04e-3)" "unprognostic (8.75e-3)" 0.6 0.1 0.2 2.2 0.1 0.0 9.6 0.5 0.3 7.6 0.7 18.1 9.9 1.1 7.4 55.2 4.9 4.1 0.1 0.2 0.0 9.9 38.8 13.3 0.0 0.1 0.1 0.2 28.9 13.4 3.3 8.0 0.1 11.6 14.7 0.0 17.8 2.6 0.2 36.5 8.2 0.5 0.0 0.0 27.0 10.8 0.3 3.4 16.7 0.0 7.1 13.0 19.2 0.2 38.6 0.2 0.1 0.0 0.0 0.0 55.5 0.2 0.0 0.1 0.2 36.7 19.1 0.0 1.7 0.0 0.0 40.4 0.1 30.1 0.0 0.1 24.1 0.1 12.5 30.9 0.6 0.0 0.2 0.0 43.4 0.0 16.4 0.1 0.0 0.1 0.1 0.0 0.0 113.2 0.0 0.3 4.1 31.4 12.0 0.1 0.0 0.2 14.5 60.4 4.2 0.0 19.6 59.8 0.1 5.4 90.1 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.6 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.2 0.2 19.2 17.2 0.0 0.3 6.4 5.3 6.8 5.7 0.8 10.7 6.9 1.0 20.0 11.1 23.9 0.0 36.3 0.3 18.8 0.0 11.0 29.1 7.3 1.4 0.4 8.4 0.0 0.0 14.0 5.5 0.5 44.9 13.8 0.0 0.6 0.4 31.1 2.7 0.0 0.0 25.3 8.2 0.8 0.8 82.4 0.9 0.2 1.8 0.0 0.6 0.3 1.0 0.0 0.0 13.7 8.5 0.0 0.3 7.9 5.1 5.6 4.2 0.2 0.0 0.2 0.7 10.4 1.2 27.2 8.5 58.4 0.5 0.0 18.3 8.9 ESYT1 "FAM62A, KIAA0747, MBC2" ENSG00000139641 "Extended synaptotagmin 1" Q9BSJ8 12 56118250-56144674 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016858, HPA076926" Approved Supported "Endoplasmic reticulum" NA NA 720000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA016858: AB_1848404, HPA076926: AB_2686819" "unprognostic (5.02e-2)" "unprognostic (3.62e-2)" "unprognostic (6.26e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (8.44e-2)" "unprognostic (5.41e-2)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (1.77e-1)" "unprognostic (6.85e-3)" "unprognostic (1.29e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.04e-2)" "unprognostic (8.43e-3)" "unprognostic (1.52e-2)" "unprognostic (3.98e-2)" 107.9 39.3 15.2 38.5 14.4 18.7 72.7 18.5 18.9 36.6 19.8 45.9 17.2 53.4 22.2 29.2 47.1 27.8 24.5 13.5 23.0 26.8 46.7 45.0 45.9 34.2 21.7 38.8 39.5 40.7 11.7 38.7 36.2 30.5 36.2 8.9 28.0 47.2 54.2 26.1 30.7 74.4 22.5 37.2 29.3 12.1 23.6 36.6 27.8 33.3 49.8 44.7 32.3 24.0 107.0 78.1 62.2 158.2 90.8 67.3 53.4 117.4 129.3 136.2 94.4 72.4 114.3 40.8 92.2 201.3 50.7 118.7 73.7 120.4 121.6 58.8 54.2 244.7 56.0 58.5 125.9 193.2 371.6 76.7 125.5 147.1 81.3 145.3 117.8 39.2 153.6 263.9 124.4 81.2 70.4 116.4 78.9 44.6 102.5 105.4 85.0 107.3 113.7 89.0 52.4 54.8 174.1 52.9 80.5 71.3 111.1 128.4 154.5 104.8 94.7 59.7 85.7 62.3 99.0 58.7 97.3 79.6 111.7 423.2 37.4 423.0 127.2 69.4 157.2 62.4 129.4 129.5 87.2 48.2 102.3 120.2 9.3 84.2 85.6 29.7 139.6 177.8 15.2 14.4 18.5 18.9 13.5 23.0 34.2 21.7 36.2 22.5 23.6 24.0 44.4 9.6 9.3 4.6 25.9 16.3 19.8 23.5 14.2 5.5 20.5 21.3 8.2 14.3 12.9 31.3 10.4 31.9 22.3 6.1 0.0 36.8 2.0 20.5 15.1 28.2 25.2 17.9 10.2 26.8 18.1 17.6 9.2 19.3 62.7 24.7 27.1 37.8 46.4 0.0 7.1 12.0 22.4 21.3 24.8 2.1 17.4 22.9 35.6 6.5 50.6 5.7 60.8 2.0 4.1 26.2 3.5 25.2 18.5 19.9 2.2 4.4 10.7 5.9 52.6 14.3 22.0 3.9 2.9 18.0 11.9 37.9 40.3 12.5 10.8 12.7 ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76215353-76311472 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 389.7;tongue: 493.5" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 402.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 680000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018990: AB_1848277, HPA018993: AB_1848275, HPA018996: AB_1848276, HPA024089: AB_1848278" "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (3.71e-3)" "unprognostic (5.99e-2)" "unprognostic (6.81e-3)" "unprognostic (3.02e-1)" "unprognostic (5.01e-2)" "unprognostic (6.01e-2)" "unprognostic (3.38e-3)" "unprognostic (1.99e-1)" "prognostic favorable (5.04e-8)" "unprognostic (2.87e-1)" "unprognostic (4.90e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" 93.0 112.3 33.8 55.0 36.0 63.0 70.4 36.0 54.6 38.7 40.3 131.4 135.6 27.0 30.6 85.1 30.1 44.7 243.0 34.2 37.6 180.0 389.7 39.0 60.9 35.6 35.7 25.6 81.6 71.0 13.9 70.9 36.0 42.2 123.5 34.3 49.3 38.2 300.8 40.1 116.3 65.7 35.5 38.8 67.7 28.4 38.2 54.5 38.7 493.5 65.9 74.0 33.1 36.9 122.4 196.7 128.2 134.8 141.7 149.1 201.0 144.4 166.2 183.0 162.8 175.3 221.3 203.5 141.3 144.3 138.5 304.6 502.7 200.2 211.9 245.8 98.0 222.2 131.4 205.2 114.7 214.5 158.7 112.7 185.9 93.1 153.5 100.0 187.8 64.7 214.1 205.2 190.3 191.2 44.9 178.2 99.9 225.3 58.4 192.8 158.6 272.8 202.1 386.9 133.3 67.2 218.2 492.2 205.0 294.4 254.1 223.4 111.4 178.2 119.5 157.0 177.4 99.0 221.0 255.9 127.8 281.1 128.5 50.0 120.3 82.7 65.4 110.3 61.7 77.3 60.6 67.6 159.4 67.3 48.8 60.1 30.2 122.9 96.1 63.4 95.8 141.9 33.8 36.0 36.0 54.6 34.2 37.6 35.6 35.7 36.0 35.5 38.2 36.9 65.7 57.7 41.6 45.1 54.3 53.4 110.8 151.5 44.9 13.1 47.2 46.4 352.9 65.8 84.5 36.8 22.9 277.4 61.1 250.9 209.4 106.5 11.7 29.5 45.1 51.8 65.4 117.8 26.0 84.1 180.8 66.8 90.2 37.0 38.6 53.1 48.9 348.8 132.3 53.8 31.5 141.6 89.5 79.0 84.5 7.9 59.4 103.0 56.9 28.1 129.0 26.7 85.5 37.2 46.9 92.1 176.2 58.3 87.8 92.4 231.1 402.9 50.2 20.4 46.0 44.0 113.7 66.4 40.5 79.5 57.1 300.2 55.5 123.4 187.3 162.0 ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 493.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1105.3;Proximal enterocytes: 710.7;Proximal tubular cells: 1118.7" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1693.9;OE19: 770.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" 159.1 171.5 121.1 44.0 134.4 70.2 115.3 134.8 145.5 55.7 123.0 97.6 136.3 48.9 16.9 140.7 53.3 62.7 387.8 112.8 120.6 144.5 493.6 50.4 58.2 129.8 124.8 55.2 81.9 106.3 73.1 39.0 125.7 55.2 41.2 24.1 172.2 37.9 280.7 79.0 129.7 31.7 119.9 64.5 90.0 53.6 132.4 81.4 70.3 280.3 36.9 65.6 69.0 137.0 118.9 304.3 41.3 113.9 129.4 150.4 65.6 82.4 61.0 63.5 63.1 257.3 192.1 121.5 80.2 129.8 33.8 104.0 83.3 171.1 19.2 182.0 323.3 98.1 188.9 1693.9 141.8 92.1 67.6 235.3 50.3 86.1 88.2 79.2 54.9 115.0 146.6 130.2 83.2 243.7 95.2 86.2 26.7 770.2 372.0 104.5 114.4 224.6 88.5 135.7 91.7 44.5 184.5 49.9 94.4 29.4 130.3 86.3 77.8 65.9 67.6 71.4 73.3 195.8 130.0 109.8 335.0 135.1 172.5 127.7 190.1 119.6 104.3 212.3 137.4 281.6 156.0 134.2 225.3 303.1 163.6 136.0 97.8 205.3 165.7 265.1 225.7 140.5 121.1 134.4 134.8 145.5 112.8 120.6 129.8 124.8 125.7 119.9 132.4 137.0 90.9 80.1 93.8 15.3 75.6 65.0 114.9 196.4 55.2 77.1 129.9 170.1 243.8 234.4 122.5 121.4 31.3 240.7 58.7 440.9 571.3 188.0 139.2 67.5 70.2 76.2 168.4 120.0 4.1 140.5 206.6 93.8 128.9 48.2 88.8 63.2 144.9 1105.3 217.5 43.7 4.2 335.2 158.7 147.7 73.4 354.4 107.5 86.9 286.4 5.6 95.2 158.8 50.4 7.1 18.9 155.4 339.4 114.3 69.9 74.9 710.7 1118.7 118.8 67.9 98.6 87.4 144.5 71.0 52.8 135.3 63.6 160.1 74.0 217.3 354.4 140.3 ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158672125-158709623 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease variant, FDA approved drug targets, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.4;tongue: 186.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 146.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041978 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041978: AB_10795605" "unprognostic (7.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.90e-2)" "unprognostic (5.92e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "prognostic favorable (5.76e-10)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-3)" "unprognostic (1.74e-1)" 34.6 38.0 13.3 10.7 14.8 9.4 16.0 13.9 15.1 10.2 25.5 32.6 63.7 10.4 8.4 25.0 9.3 11.1 93.3 12.8 14.5 46.5 196.4 9.2 8.7 12.3 13.8 10.8 20.4 32.8 9.8 13.0 12.8 13.7 26.9 15.8 21.8 13.2 111.0 18.7 51.4 14.8 12.5 9.5 26.9 11.2 15.0 9.4 13.2 186.9 14.3 12.9 12.8 15.1 13.2 9.2 12.2 21.4 47.2 28.8 6.6 21.3 19.4 13.9 14.3 3.7 24.6 27.8 4.6 24.1 15.8 13.8 22.1 20.9 19.2 51.5 20.3 26.5 17.3 8.0 20.8 24.0 23.4 26.5 23.8 15.8 12.8 20.8 27.3 20.7 15.6 53.8 22.2 14.7 22.7 11.0 5.0 33.2 19.4 18.4 4.3 21.9 21.2 10.6 18.7 8.0 21.0 39.5 21.8 10.0 30.4 17.6 13.6 11.9 6.7 18.5 12.2 31.3 42.1 20.3 24.6 19.2 13.5 3.7 21.5 41.5 10.1 22.6 12.7 10.3 9.8 10.4 18.3 9.6 11.6 9.9 7.8 10.5 20.9 13.1 16.1 9.5 13.3 14.8 13.9 15.1 12.8 14.5 12.3 13.8 12.8 12.5 15.0 15.1 18.1 12.8 10.3 55.2 18.5 33.0 46.0 27.2 29.6 29.2 12.6 13.8 146.6 14.3 22.8 18.4 64.6 24.9 18.0 34.4 29.4 14.4 4.2 12.5 12.5 17.7 18.0 30.7 43.2 11.7 9.9 23.9 44.4 14.2 5.1 19.2 12.8 85.7 13.4 25.2 71.9 22.5 30.5 14.4 15.8 4.7 23.0 13.3 8.8 15.0 12.2 13.9 10.3 55.8 58.0 11.7 29.4 23.7 30.1 21.3 58.3 26.8 13.1 43.9 32.9 27.4 30.4 43.2 29.8 32.7 36.9 43.0 19.7 15.7 26.2 38.7 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 ETV7 "TEL-2, TEL2" ENSG00000010030 "ETS variant transcription factor 7" Q9Y603 6 36354091-36387800 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.0;skin 1: 15.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Cytotrophoblasts: 28.8;Exocrine glandular cells: 23.8;Proximal enterocytes: 21.5;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9;T-reg: 16.3" "Group enriched" "Detected in many" 4 "granulocytes: 18.9;monocytes: 5.7;T-cells: 16.3" "Cell line enhanced" "Detected in some" "BEWO: 27.1;BJ hTERT+ SV40 Large T+: 14.7;BJ hTERT+ SV40 Large T+ RasG12V: 27.8;HDLM-2: 59.7" "Low region specificity" "Detected in all" HPA029033 Uncertain Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA029033: AB_10601375" "unprognostic (1.67e-2)" "prognostic favorable (5.16e-4)" "unprognostic (9.48e-2)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" "unprognostic (2.62e-3)" "unprognostic (9.08e-2)" "unprognostic (4.11e-2)" "unprognostic (2.08e-2)" "prognostic favorable (5.32e-4)" "unprognostic (6.81e-3)" "unprognostic (1.11e-1)" "unprognostic (1.69e-3)" "unprognostic (5.54e-2)" "unprognostic (4.93e-1)" "unprognostic (1.27e-2)" "prognostic favorable (2.95e-6)" 1.9 2.1 1.5 6.9 1.5 0.9 2.1 1.0 1.7 2.1 1.4 3.3 16.0 1.0 1.3 3.6 2.2 3.4 0.4 1.5 1.4 2.3 2.9 4.9 5.3 2.2 1.2 1.5 1.6 2.2 3.8 3.6 2.1 2.9 2.6 0.4 8.6 1.5 0.2 15.4 12.7 1.0 2.1 3.1 6.2 1.1 1.4 4.0 1.2 0.3 3.9 5.5 2.5 1.4 3.2 0.0 0.2 0.1 0.0 0.2 27.1 0.0 9.2 14.7 27.8 0.5 6.2 0.1 0.7 0.2 2.3 3.3 0.4 1.7 0.7 59.7 0.5 0.5 0.0 0.0 1.8 0.0 0.3 1.2 2.4 0.7 0.2 0.0 0.4 0.0 0.1 0.2 0.3 0.1 0.2 0.3 0.2 0.3 0.1 6.1 0.1 0.2 0.2 1.1 0.8 0.0 0.6 2.1 0.5 0.0 3.1 0.6 0.2 0.3 0.7 0.3 0.1 0.1 0.1 0.2 0.0 2.7 0.4 0.0 3.7 0.3 1.6 5.7 3.9 3.3 5.4 2.2 0.9 2.4 1.0 1.4 18.9 0.6 1.9 0.0 16.3 2.5 1.5 1.5 1.0 1.7 1.5 1.4 2.2 1.2 2.1 2.1 1.4 1.4 1.4 19.2 14.8 0.3 1.2 2.0 2.2 8.0 6.2 0.2 2.5 2.7 0.5 7.2 7.1 0.0 0.0 28.8 0.7 6.6 0.0 12.4 0.4 0.4 1.4 1.1 3.6 0.0 0.5 23.8 6.6 2.7 8.2 0.7 2.5 1.7 0.0 0.4 2.9 0.0 0.3 6.5 6.1 1.3 1.6 0.5 1.5 1.0 3.6 0.0 6.5 3.1 1.0 0.0 0.3 13.4 7.8 1.2 5.6 4.8 21.5 1.3 3.0 0.6 0.0 1.0 5.5 0.9 26.8 6.4 3.7 8.5 3.6 0.7 7.6 4.8 EVI2B "CD361, D17S376, EVDB" ENSG00000185862 "Ecotropic viral integration site 2B" P34910 17 31303770-31314105 "CD markers, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.0;lymphoid tissue: 169.8" "Cell type enhanced" "Detected in many" "B-cells: 233.2;Kupffer cells: 522.3;Langerhans cells: 169.8;Macrophages: 271.9;monocytes: 426.4;T-cells: 170.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1366.0" "Group enriched" "Detected in all" 5 "granulocytes: 1366.0;monocytes: 381.9" "Cell line enhanced" "Detected in many" "Daudi: 87.9;HL-60: 99.9;HMC-1: 133.3;Karpas-707: 96.4;NB-4: 79.4;RPMI-8226: 147.7;THP-1: 124.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007346, HPA053383" Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA007346: , HPA053383: " "unprognostic (1.07e-2)" "unprognostic (1.20e-2)" "unprognostic (5.97e-2)" "unprognostic (4.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.56e-2)" "unprognostic (3.32e-2)" "unprognostic (8.64e-2)" "unprognostic (2.73e-2)" 24.6 11.0 6.4 100.9 7.3 189.0 13.8 7.3 11.6 13.1 8.7 27.9 23.7 7.4 4.3 11.8 7.8 30.5 6.7 6.3 8.4 5.1 24.9 61.1 159.5 13.3 10.3 5.5 3.0 3.8 1.8 15.4 10.8 7.4 30.5 1.2 11.8 6.1 2.0 5.1 39.2 17.0 7.7 158.8 33.7 3.7 8.5 76.4 5.3 12.2 169.8 38.5 4.1 11.1 0.6 0.7 0.0 0.0 6.5 8.3 0.1 0.8 5.8 6.7 12.4 0.0 3.4 87.9 0.1 5.5 26.4 0.6 0.0 1.2 7.5 0.1 0.0 2.1 0.0 0.0 66.0 99.9 133.3 15.3 0.0 3.9 5.3 2.2 6.9 7.3 1.4 96.4 19.8 0.0 29.4 79.4 0.1 0.0 0.0 51.0 0.4 147.7 0.3 0.2 0.0 0.1 0.4 0.2 0.5 0.0 0.0 124.8 7.2 1.9 0.2 0.7 7.0 18.4 0.9 18.9 8.6 34.0 2.2 1005.3 328.9 798.7 79.2 240.1 76.8 183.6 120.8 102.8 149.9 146.2 91.9 87.5 1366.0 44.2 381.9 86.3 173.6 251.4 6.4 7.3 7.3 11.6 6.3 8.4 13.3 10.3 10.8 7.7 8.5 11.1 2.1 0.0 14.8 0.7 233.2 5.4 0.7 0.7 1.8 0.2 1.5 1.7 1.0 2.8 6.7 1.8 0.0 0.6 129.0 1.3 0.0 0.3 8.3 0.1 0.3 5.6 0.0 6.5 2.7 0.0 0.8 4.0 1.5 0.4 82.2 0.0 7.5 2.3 89.1 0.0 3.1 0.1 2.0 522.3 169.8 9.0 0.0 271.9 37.4 11.2 426.4 0.0 117.4 4.0 31.7 1.0 0.0 0.4 110.4 0.4 0.1 1.1 2.4 0.8 19.7 1.2 1.9 0.4 0.4 0.4 3.7 0.3 170.9 0.0 1.3 1.1 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 232.8;placenta: 489.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 863.3;Langerhans cells: 205.1;Macrophages: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.1;myeloid DC: 179.6" "Group enriched" "Detected in many" 184 "dendritic cells: 179.6;granulocytes: 50.2;monocytes: 141.1" "Cell line enhanced" "Detected in some" "AF22: 24.0;LHCN-M2: 8.9;RH-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 4: Macrophages - Innate immune response" "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 232.8 57.9 2.6 52.3 4.2 16.1 46.9 1.3 13.0 50.4 28.5 45.9 9.7 18.5 5.6 51.2 29.1 52.7 39.2 2.1 3.6 21.0 3.0 38.7 30.0 8.3 4.6 10.7 10.0 13.3 8.1 489.2 6.9 8.8 63.9 21.6 18.8 13.4 10.3 22.7 22.0 89.6 2.6 8.8 25.4 17.8 3.7 20.9 17.1 32.8 12.5 144.5 12.1 4.0 0.0 0.1 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 43.8 0.8 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 50.2 141.1 1.4 0.5 25.4 0.6 0.4 0.3 0.4 179.6 0.4 0.4 0.2 32.9 0.3 0.7 12.5 0.3 364.9 2.6 4.2 1.3 13.0 2.1 3.6 8.3 4.6 6.9 2.6 3.7 4.0 2.0 0.0 1.9 0.3 1.8 18.7 0.0 0.0 0.6 0.1 0.3 0.4 10.6 5.7 0.0 0.0 0.0 5.0 4.5 0.0 0.0 0.0 5.1 0.6 10.6 3.8 0.0 1.3 3.9 0.0 5.6 13.7 0.0 0.4 1.3 0.0 2.9 0.9 863.3 0.0 1.4 0.0 0.0 92.4 205.1 5.8 4.4 232.0 19.6 64.6 53.1 0.9 6.2 0.5 0.7 0.1 0.0 0.7 1.2 0.0 0.0 11.0 2.2 6.5 59.2 2.5 3.3 1.6 0.9 1.2 15.2 10.1 2.6 0.4 0.0 0.1 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 F8A1 "DXS522E, F8A" ENSG00000277203 "Coagulation factor VIII associated 1" P23610 X 154886349-154888061 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 49.0;Proximal tubular cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.72e-2)" "prognostic favorable (1.67e-6)" "unprognostic (2.92e-2)" "unprognostic (2.57e-1)" "unprognostic (6.88e-2)" "unprognostic (6.61e-2)" "unprognostic (4.18e-3)" "unprognostic (3.31e-2)" "unprognostic (7.96e-2)" "unprognostic (9.23e-3)" "unprognostic (1.20e-1)" "unprognostic (1.80e-1)" "unprognostic (3.68e-2)" "unprognostic (6.28e-2)" "unprognostic (6.16e-2)" "unprognostic (5.61e-2)" "unprognostic (2.69e-1)" 23.1 23.7 30.6 12.9 30.1 33.1 21.0 25.4 39.5 13.8 22.4 19.6 15.2 18.8 22.7 17.6 13.3 7.4 25.5 31.7 29.8 22.8 44.6 17.1 19.3 30.8 28.2 8.8 22.2 14.0 13.7 13.0 31.9 16.3 14.9 14.8 21.8 18.1 27.6 16.5 20.1 14.8 26.2 23.1 15.6 5.8 31.3 20.6 19.6 18.1 20.0 19.4 13.3 32.2 106.4 47.2 9.1 14.7 31.3 14.8 0.2 27.5 22.9 27.8 36.0 18.6 40.2 11.4 87.9 16.7 36.3 11.0 13.3 12.7 22.8 63.3 6.3 11.6 13.3 18.8 9.5 21.1 5.6 28.6 11.6 9.2 5.2 20.6 6.0 29.1 1.2 41.8 16.2 53.8 34.0 94.9 16.3 0.0 54.7 64.1 9.0 10.0 31.8 35.9 45.7 19.0 16.7 20.1 36.4 0.0 23.7 41.6 17.1 15.7 36.0 11.6 22.1 41.6 43.9 101.4 8.3 76.7 36.0 0.0 3.0 6.8 2.9 3.1 1.6 1.5 3.2 3.5 3.5 2.5 3.6 4.0 6.0 0.8 1.2 4.2 1.6 1.7 30.6 30.1 25.4 39.5 31.7 29.8 30.8 28.2 31.9 26.2 31.3 32.2 5.5 12.8 2.6 5.5 14.4 6.6 5.2 1.8 2.2 12.1 14.4 12.4 13.6 27.1 1.5 40.5 6.2 4.0 19.5 11.9 49.0 2.7 0.3 9.2 11.9 7.1 6.7 9.5 7.2 2.0 6.2 7.4 6.6 9.7 5.7 7.6 7.5 24.6 11.2 3.3 6.1 10.2 4.1 27.3 16.8 1.5 10.8 16.9 10.6 7.5 16.7 7.3 30.9 6.6 9.6 2.5 5.7 12.4 4.7 3.1 10.4 57.9 2.7 7.0 6.6 4.6 6.1 0.4 1.5 7.6 6.5 1.6 19.0 8.9 9.8 2.8 FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394317-46413848 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 128.5;Proximal enterocytes: 87.4;Spermatocytes: 89.0" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 29.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 37.5;OE19: 18.8;RT4: 42.4;SK-BR-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favorable (4.25e-5)" "prognostic favorable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" 7.5 14.2 23.5 2.9 28.4 10.4 9.5 25.6 29.6 7.5 29.3 18.9 22.0 3.9 9.1 8.7 12.0 5.2 5.0 24.6 23.3 20.0 32.8 7.8 2.5 32.1 25.4 3.9 22.4 24.6 19.0 3.4 28.7 44.1 15.2 5.5 17.4 7.1 9.5 12.1 22.0 2.3 27.9 3.3 17.1 46.8 26.4 7.1 38.6 5.6 2.7 6.9 8.2 45.8 5.0 1.2 0.8 1.0 1.2 0.8 37.5 1.0 0.5 0.5 0.8 7.3 11.4 0.3 3.9 0.7 0.4 16.2 0.7 2.3 0.2 2.2 5.4 0.1 0.2 3.5 0.8 1.4 2.8 0.6 10.7 0.4 1.3 0.4 0.0 0.9 0.1 0.8 0.0 10.7 0.8 2.2 3.2 18.8 0.4 0.9 0.4 0.2 9.0 42.4 4.8 3.6 5.6 21.2 0.2 0.9 14.6 14.5 0.0 0.1 0.6 1.1 0.7 2.1 1.0 0.6 0.1 13.4 0.4 0.0 6.9 29.1 0.4 1.9 0.2 0.1 0.4 0.2 8.2 0.1 0.6 0.6 0.4 0.5 1.0 8.8 0.2 1.4 23.5 28.4 25.6 29.6 24.6 23.3 32.1 25.4 28.7 27.9 26.4 45.8 1.2 22.4 13.2 6.5 2.4 5.2 29.0 6.8 10.2 15.5 15.4 9.0 2.9 27.1 11.0 22.0 43.8 16.3 7.3 51.6 0.0 12.4 50.7 9.5 1.9 1.8 15.5 6.6 15.7 6.4 8.7 3.7 37.8 6.0 0.0 6.3 0.4 37.1 2.8 1.7 11.4 38.2 10.2 2.5 4.2 128.5 7.5 3.3 5.4 1.9 2.5 7.3 0.0 7.5 45.1 4.2 41.3 4.5 0.7 20.1 87.4 22.6 5.2 14.5 0.0 2.9 3.2 89.0 23.0 6.4 6.0 12.4 1.2 1.3 55.2 18.9 FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adipose tissue: 3787.4;breast: 2195.7" "Cell type enriched" "Detected in many" 17 "Adipocytes: 24359.7" "Group enriched" "Detected in all" 7 "breast cancer: 42.1;cervical cancer: 141.7;head and neck cancer: 133.8;urothelial cancer: 65.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 171 "ASC diff: 4051.5;RT4: 2107.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002188, CAB024961" Enhanced NA NA 22000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB024961: , HPA002188: AB_1078822" "unprognostic (4.81e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-3)" "unprognostic (2.63e-2)" "unprognostic (2.58e-1)" "unprognostic (8.70e-3)" "unprognostic (1.78e-3)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" "unprognostic (8.76e-2)" "unprognostic (1.13e-3)" "unprognostic (4.48e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-1)" 3787.4 42.2 0.8 46.7 1.1 2.8 2195.7 0.9 1.6 9.9 34.8 52.9 2.8 4.6 0.6 15.1 10.9 68.1 121.8 1.2 0.8 7.0 5.1 113.5 13.6 0.8 0.8 4.2 16.6 59.1 1.4 186.9 0.8 4.3 33.5 2.6 58.8 5.0 66.7 65.2 44.7 14.2 0.7 6.7 26.5 1.1 3.8 29.8 83.0 166.7 2.0 242.7 18.9 0.9 0.0 0.0 0.0 0.0 4051.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 17.9 0.0 0.1 1.3 0.0 0.4 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.8 1.2 0.1 3.0 0.0 9.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 2107.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.2 5.7 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 1.6 1.2 0.8 0.8 0.8 0.8 0.7 3.8 0.9 24359.7 35.3 64.3 0.0 19.4 14.4 1.1 0.9 4.6 0.5 71.7 196.2 42.1 0.0 26.7 0.0 0.0 0.5 73.6 0.0 0.0 0.2 1.6 0.4 8.8 1132.7 0.0 0.0 0.0 5.6 0.7 53.1 1.1 0.2 27.8 0.1 23.2 0.4 114.2 0.0 0.0 0.0 0.0 50.4 15.7 10.9 1.5 192.7 16.0 0.0 0.6 0.9 0.0 0.0 0.0 0.2 2.2 1.2 2.7 0.5 0.0 0.3 21.9 2.4 716.6 62.2 1364.8 0.0 0.1 1.2 13.9 0.7 18.7 2.3 0.0 55.3 FABP9 "PERF, PERF15, T-FABP" ENSG00000205186 "Fatty acid binding protein 9" Q0Z7S8 8 81458253-81461579 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 40.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073619 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA073619: AB_2732229" "unprognostic (2.99e-1)" 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 40.9 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.2 0.2 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FADS3 "CYB5RP, LLCDL3" ENSG00000221968 "Fatty acid desaturase 3" Q9Y5Q0 11 61873519-61892051 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.6;Extravillous trophoblasts: 138.4;Rod photoreceptor cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.7;naive B-cell: 8.7" "Group enriched" "Detected in many" 4 "B-cells: 8.7;granulocytes: 5.7;T-cells: 2.1" "Cell line enhanced" "Detected in all" "ASC diff: 283.2;HHSteC: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045224 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "HPA045224: AB_10967570" "unprognostic (4.69e-3)" "unprognostic (1.31e-2)" "unprognostic (5.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.91e-2)" "prognostic unfavorable (9.54e-5)" "unprognostic (1.76e-3)" "unprognostic (3.46e-1)" "unprognostic (6.45e-2)" "unprognostic (1.49e-1)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.50e-9)" "unprognostic (1.14e-1)" "unprognostic (3.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.37e-1)" 105.0 72.3 37.1 23.4 37.3 5.1 72.5 29.6 50.7 31.2 55.3 27.5 4.8 27.9 31.7 9.5 26.7 12.1 88.9 36.9 35.2 29.4 23.7 45.4 21.6 34.8 33.7 35.7 25.4 11.4 14.1 64.0 38.9 21.3 4.6 15.0 14.3 13.1 45.2 13.4 28.1 19.4 29.8 22.3 22.7 13.4 37.3 4.3 18.1 14.8 20.9 36.7 21.4 35.3 37.3 11.4 3.6 22.5 283.2 57.0 71.5 73.1 177.9 77.0 73.7 16.2 13.3 27.5 46.5 147.1 60.0 20.1 13.7 199.4 40.8 7.9 7.6 22.7 48.9 32.8 243.6 2.1 4.5 62.5 85.2 92.4 175.4 46.8 90.1 14.3 22.2 50.8 132.6 42.7 8.3 11.3 10.7 4.1 29.4 46.4 142.8 76.8 86.0 13.0 5.7 7.2 83.4 11.2 77.9 29.9 16.4 5.0 61.2 74.5 51.1 22.0 32.6 15.5 8.0 35.0 62.4 11.2 55.2 0.0 0.7 5.7 1.6 1.2 1.4 7.7 1.4 2.1 0.6 8.7 0.1 0.5 0.3 0.6 0.8 0.0 0.4 0.6 37.1 37.3 29.6 50.7 36.9 35.2 34.8 33.7 38.9 29.8 37.3 35.3 164.6 32.1 5.2 54.5 39.0 6.8 8.2 15.6 2.8 11.2 23.3 26.2 19.5 18.6 2.0 5.5 8.4 38.9 15.2 35.7 1.9 46.4 17.4 8.2 31.2 57.7 6.7 13.0 31.6 20.6 138.4 31.3 16.8 13.1 7.0 12.4 20.3 9.8 19.7 1.7 10.0 21.0 0.0 3.9 43.0 14.0 28.6 16.5 35.6 8.4 8.0 48.5 5.2 17.1 17.6 16.4 6.7 17.7 13.1 10.7 6.3 13.9 2.9 120.3 19.7 97.3 90.2 2.0 5.5 3.5 5.5 68.0 17.6 16.1 15.8 4.3 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 301.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 266.8;Proximal tubular cells: 305.5" "Cancer enhanced" "Detected in all" "liver cancer: 23.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 99.2 65.4 16.0 7.0 17.1 20.0 59.0 16.6 21.1 19.2 15.1 13.8 14.6 19.3 50.4 15.2 23.0 9.7 20.3 16.3 18.8 65.0 301.5 20.0 5.7 17.9 19.6 26.4 9.9 18.4 16.8 7.8 16.9 16.6 11.9 1.6 14.8 13.6 31.0 10.9 16.8 13.5 17.2 19.1 14.2 20.8 17.4 6.7 14.5 27.7 5.8 16.4 15.8 17.5 20.1 34.4 13.5 17.0 60.2 62.2 32.9 24.3 56.8 26.2 22.3 22.0 35.9 0.4 39.0 52.6 36.8 29.1 46.8 59.6 25.1 12.5 28.5 166.6 18.0 112.1 316.6 79.6 88.8 107.5 37.1 22.9 39.7 84.2 37.4 38.3 71.1 35.7 50.3 31.0 22.3 42.0 9.9 15.5 37.6 12.2 19.3 123.4 77.0 25.2 0.7 8.3 27.4 76.7 77.9 21.6 58.3 55.0 126.1 46.8 30.0 25.5 42.7 32.7 69.5 13.8 99.6 187.5 26.9 34.5 18.8 3.3 9.6 8.1 2.3 0.1 2.4 6.0 25.3 0.1 3.1 2.7 1.3 5.7 8.4 1.9 2.5 9.7 16.0 17.1 16.6 21.1 16.3 18.8 17.9 19.6 16.9 17.2 17.4 17.5 3.0 3.2 13.8 9.8 4.1 6.8 17.5 30.8 15.4 0.4 19.1 13.7 15.5 21.5 12.5 33.1 0.0 37.9 4.9 9.3 52.8 9.3 7.5 3.0 16.2 3.2 4.2 24.4 0.4 3.5 14.1 16.6 3.6 4.0 41.9 6.3 8.9 266.8 72.5 0.0 2.5 13.0 24.4 21.4 6.6 13.5 9.9 30.5 19.6 1.0 5.7 7.3 3.1 2.5 0.6 4.5 12.8 7.9 5.2 9.7 54.1 305.5 5.3 0.4 0.0 9.2 11.2 1.5 2.1 18.2 5.7 22.0 7.7 8.7 22.4 16.4 FAIM "FAIM1, FLJ10582" ENSG00000158234 "Fas apoptotic inhibitory molecule" Q9NVQ4 3 138608606-138633376 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 235.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 173.3;Rod photoreceptor cells: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 135.7" "Low region specificity" "Detected in all" "HPA042440, HPA052209" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA042440: AB_2677999, HPA052209: AB_2681761" "unprognostic (6.45e-2)" "unprognostic (8.21e-3)" "unprognostic (5.97e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.96e-5)" "unprognostic (4.84e-2)" "unprognostic (4.15e-2)" "unprognostic (9.23e-3)" "unprognostic (2.29e-1)" "unprognostic (2.63e-2)" "prognostic favorable (6.63e-4)" "unprognostic (4.76e-2)" "unprognostic (3.51e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" 18.3 8.6 16.8 6.9 17.9 4.1 15.6 17.5 21.3 31.7 14.9 9.3 6.4 12.6 19.5 12.2 38.2 12.1 6.4 16.2 18.6 15.3 8.2 10.5 10.8 18.9 17.7 10.8 38.1 8.5 10.4 8.4 19.4 14.9 7.9 235.0 9.6 21.7 5.4 8.5 6.1 9.7 19.2 4.9 9.8 7.3 17.1 19.8 20.3 5.5 13.7 13.5 10.4 19.9 80.8 15.5 1.7 13.9 14.7 27.2 55.4 24.4 14.7 25.2 21.5 26.8 23.2 0.2 21.0 32.0 29.0 20.9 66.8 13.9 28.2 66.2 69.8 15.1 42.9 39.1 16.3 0.0 4.8 38.4 26.5 9.4 14.4 15.4 27.5 5.7 10.0 20.0 15.8 30.7 0.4 68.3 30.1 2.5 15.3 81.4 18.0 2.1 40.4 39.5 26.0 22.1 43.2 23.8 64.6 16.4 40.1 20.0 16.9 5.1 11.9 25.9 12.0 0.0 0.4 135.7 20.8 0.2 21.0 16.8 2.9 2.2 10.5 3.3 9.6 17.0 5.8 8.4 6.3 12.0 3.8 9.8 0.4 18.8 2.2 4.3 6.9 4.3 16.8 17.9 17.5 21.3 16.2 18.6 18.9 17.7 19.4 19.2 17.1 19.9 16.4 19.2 22.9 9.1 12.7 10.8 30.3 35.2 14.2 31.9 14.3 21.5 5.3 68.6 32.4 25.8 66.7 42.0 14.7 5.9 31.3 63.1 12.0 173.3 29.8 14.5 21.1 7.2 7.7 50.0 33.3 16.8 8.2 41.3 41.2 17.2 8.9 9.4 25.2 15.2 6.1 8.8 14.2 3.2 5.7 16.5 17.4 6.5 16.0 1.9 15.6 45.3 21.6 11.1 16.5 31.3 4.4 19.9 14.2 22.1 2.2 28.1 77.5 228.3 0.0 25.0 22.6 14.1 4.2 16.6 13.1 14.6 10.8 14.6 11.7 21.6 FAM124A FLJ30707 ENSG00000150510 "Family with sequence similarity 124 member A" Q86V42 13 51222334-51284239 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 59.1;choroid plexus: 26.7;retina: 25.7" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 232.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HAP1: 18.0;HUVEC TERT2: 10.6;NTERA-2: 35.1;SH-SY5Y: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048182 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA048182: AB_2680301" "unprognostic (3.94e-3)" "unprognostic (8.76e-2)" "unprognostic (8.05e-2)" "unprognostic (1.05e-2)" "unprognostic (3.34e-1)" "unprognostic (8.37e-2)" "unprognostic (2.59e-2)" "unprognostic (2.08e-3)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "unprognostic (2.43e-2)" "unprognostic (2.03e-1)" "unprognostic (1.24e-1)" "unprognostic (7.38e-3)" "unprognostic (4.51e-2)" "unprognostic (4.54e-3)" "unprognostic (1.05e-2)" 4.6 1.8 13.2 2.7 32.1 0.2 2.9 24.0 22.0 2.2 26.7 8.1 0.6 3.1 4.6 1.2 3.1 2.4 4.9 14.8 20.8 3.7 0.7 1.9 0.8 33.8 27.4 0.8 1.4 0.6 1.3 3.6 31.3 4.6 1.3 25.7 7.3 4.4 1.0 1.0 2.0 5.2 18.4 8.3 3.3 1.2 25.9 3.1 2.4 1.3 0.5 4.5 1.6 59.1 0.0 1.7 1.2 1.1 0.3 0.1 0.1 0.2 0.6 0.2 0.2 0.1 0.6 0.6 0.0 0.0 2.2 0.1 18.0 0.2 0.1 0.1 2.7 0.1 0.5 0.0 1.4 0.9 1.1 0.4 0.2 0.5 0.0 0.0 10.6 4.8 0.1 0.1 0.0 0.3 4.6 0.3 35.1 0.3 2.8 1.0 0.1 2.6 0.0 0.1 2.5 13.3 0.6 2.2 2.0 2.6 0.3 1.1 0.2 0.1 1.2 0.9 1.3 0.3 0.0 0.0 1.6 3.2 1.5 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 13.2 32.1 24.0 22.0 14.8 20.8 33.8 27.4 31.3 18.4 25.9 59.1 8.5 0.0 0.0 17.6 0.4 0.8 2.1 0.0 0.6 10.2 1.1 1.8 10.8 0.0 0.0 1.8 50.1 0.0 0.8 0.2 3.9 2.6 4.7 0.8 3.5 9.3 0.0 0.0 12.0 0.8 0.0 2.2 0.0 1.6 1.3 0.6 8.6 0.1 0.2 6.7 4.8 0.0 0.0 0.6 0.3 5.8 0.6 1.4 3.6 9.4 0.0 3.6 0.0 10.6 232.9 0.7 0.0 0.4 0.0 2.3 0.0 11.7 1.5 43.6 0.0 1.8 2.0 1.7 1.6 0.1 0.1 0.0 0.6 0.7 0.1 0.5 FAM124B FLJ22746 ENSG00000124019 "Family with sequence similarity 124 member B" Q9H5Z6 2 224378698-224402107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 8.5" "Group enriched" "Detected in some" 4 "Adipocytes: 13.8;Endothelial cells: 10.8;Erythroid cells: 9.4;granulocytes: 4.5" "Cancer enriched" "Detected in many" 10 "testis cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 29.5;eosinophil: 17.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "HUVEC TERT2: 103.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA070240 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA070240: AB_2686238" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "unprognostic (6.87e-3)" "unprognostic (2.49e-1)" "unprognostic (7.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.28e-2)" "unprognostic (5.78e-2)" "unprognostic (3.19e-1)" "unprognostic (1.85e-1)" "unprognostic (1.57e-1)" "unprognostic (3.36e-1)" "unprognostic (7.61e-3)" "unprognostic (1.36e-2)" "unprognostic (4.30e-1)" "unprognostic (2.25e-1)" "unprognostic (5.80e-3)" 5.2 0.5 1.4 1.1 1.2 4.7 4.3 1.4 1.7 1.5 0.9 0.9 1.0 1.6 0.3 1.4 1.2 1.2 1.8 1.3 1.6 0.6 1.9 2.3 0.7 1.8 1.7 0.4 0.4 2.4 0.2 8.5 1.5 0.5 1.0 0.2 0.8 0.5 1.2 1.8 1.0 2.3 1.6 0.5 0.6 0.3 1.7 1.1 1.0 4.6 0.7 1.5 1.4 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 15.0 0.0 0.1 0.0 0.0 0.0 103.4 0.0 4.8 0.2 0.0 0.1 0.0 0.1 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.7 7.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.5 3.0 17.2 0.2 2.3 0.0 0.0 0.7 0.0 7.9 0.0 0.0 0.0 0.1 5.4 0.8 0.0 2.5 1.1 1.4 1.2 1.4 1.7 1.3 1.6 1.8 1.7 1.5 1.6 1.7 1.1 13.8 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 1.2 0.3 0.2 10.8 0.0 9.4 0.2 0.0 0.1 0.4 0.0 0.8 4.5 0.0 2.2 0.4 0.4 0.0 0.2 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 1.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.1 1.1 0.1 0.0 0.0 FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 65.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.6;Sertoli cells: 65.7;Smooth muscle cells: 105.1" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 8.7;BJ hTERT+: 23.5;BJ hTERT+ SV40 Large T+ RasG12V: 22.1;HHSteC: 6.3;HSkMC: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" 14.7 14.9 3.3 0.8 4.4 0.0 10.9 1.9 7.0 13.2 2.5 3.3 0.9 5.8 7.5 4.4 10.1 5.2 9.1 4.6 2.7 4.5 0.9 17.9 1.5 3.0 2.5 5.7 1.7 3.7 6.6 65.2 2.7 6.2 2.1 0.2 8.2 13.4 5.4 3.0 2.3 3.7 2.7 0.1 3.5 2.5 2.8 1.8 9.7 10.6 1.2 7.9 9.9 4.7 0.0 0.0 0.0 0.0 2.3 0.1 0.0 8.7 23.5 3.7 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 1.9 7.0 4.6 2.7 3.0 2.5 2.7 2.7 2.8 4.7 34.6 0.0 0.0 1.3 0.0 1.3 0.1 0.0 1.2 0.0 0.9 0.8 0.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 16.9 0.7 15.7 13.7 0.0 0.0 14.8 0.0 0.2 14.1 0.0 0.4 0.0 0.1 3.6 0.0 0.5 0.0 6.9 0.0 0.0 0.0 2.1 2.2 2.1 0.7 1.8 3.7 0.0 0.0 0.0 6.6 0.5 0.2 0.0 5.3 0.0 0.2 0.0 0.1 0.0 0.1 65.7 2.2 105.1 10.3 5.9 0.6 0.9 0.5 2.3 0.1 0.0 0.0 FAM166B ENSG00000215187 "Family with sequence similarity 166 member B" A8MTA8 9 35561831-35563899 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "adrenal gland: 270.0;fallopian tube: 83.1;skeletal muscle: 185.9" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 108.0;Respiratory ciliated cells: 126.4" "Group enriched" "Detected in many" 5 "endometrial cancer: 11.7;ovarian cancer: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045540 Enhanced NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA045540: AB_10962627" "unprognostic (4.18e-5)" "unprognostic (7.56e-3)" "unprognostic (1.65e-1)" "prognostic favorable (2.61e-5)" "unprognostic (5.66e-3)" "unprognostic (3.48e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-2)" "unprognostic (2.21e-1)" "prognostic favorable (6.20e-6)" "unprognostic (3.69e-3)" "unprognostic (9.09e-2)" "unprognostic (4.37e-3)" "unprognostic (5.82e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (3.52e-5)" 5.2 270.0 1.9 0.0 1.5 0.0 2.5 1.2 1.2 3.6 8.8 0.3 0.0 1.3 9.0 0.6 83.1 0.1 0.5 1.7 2.3 0.7 0.6 4.2 0.1 4.7 7.0 0.3 0.2 0.1 0.4 0.0 4.5 0.3 0.2 0.1 0.7 0.6 185.9 0.6 0.6 0.1 5.5 0.2 0.4 0.2 2.2 0.0 0.3 18.3 0.3 0.2 0.2 2.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.5 1.2 1.2 1.7 2.3 4.7 7.0 4.5 5.5 2.2 2.7 0.3 0.0 0.5 0.0 0.0 4.7 1.2 9.2 2.2 0.0 0.3 2.4 0.3 0.0 10.1 0.0 2.1 0.2 0.3 0.0 0.0 0.2 0.3 108.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.2 0.0 0.1 0.4 0.5 0.1 0.0 0.1 0.0 24.4 0.0 0.7 0.3 0.3 0.3 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 3.3 126.4 0.2 0.0 3.1 3.3 0.2 0.2 2.0 2.0 0.0 0.3 2.1 0.2 0.5 FAM219B "C15orf17, FLJ00005" ENSG00000178761 "Family with sequence similarity 219 member B" Q5XKK7 15 74899992-74906883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048929, HPA058064" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Golgi apparatus" "HPA048929: AB_2680561, HPA058064: AB_2683592" "unprognostic (1.12e-1)" "unprognostic (6.10e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.08e-2)" "unprognostic (1.05e-2)" "unprognostic (5.65e-2)" "unprognostic (2.41e-2)" "unprognostic (5.66e-3)" "unprognostic (1.32e-1)" "unprognostic (1.92e-1)" "unprognostic (3.17e-2)" "unprognostic (3.11e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (4.91e-3)" 21.9 19.8 31.5 9.9 30.8 6.4 13.7 31.9 35.5 15.4 32.5 17.1 12.0 16.8 22.5 23.6 22.3 10.6 30.3 31.6 36.3 16.1 6.6 16.9 15.2 32.7 33.6 19.5 13.0 32.4 28.1 13.3 35.0 24.0 14.6 44.7 18.2 17.0 18.7 22.0 13.9 17.8 31.6 24.3 15.3 6.3 34.4 8.5 18.2 25.1 17.4 20.1 16.0 31.3 6.6 9.6 25.9 11.4 42.9 31.6 11.6 18.7 9.8 16.7 10.5 9.1 18.0 12.9 10.4 13.0 16.8 16.8 35.9 10.3 9.1 32.5 20.4 12.3 22.9 7.7 20.3 11.9 16.2 19.2 47.3 7.3 13.7 36.0 18.7 9.6 9.6 15.4 17.1 5.5 7.1 10.4 14.3 19.4 14.4 19.0 9.0 9.7 25.7 21.1 21.7 14.1 20.9 11.6 33.7 27.1 23.3 14.0 21.7 13.5 7.3 11.4 15.2 11.6 12.1 5.5 17.1 24.2 13.8 3.8 1.0 6.9 1.4 0.9 2.4 2.2 2.1 1.2 1.0 2.0 0.9 1.5 1.2 1.8 1.3 0.1 0.2 1.3 31.5 30.8 31.9 35.5 31.6 36.3 32.7 33.6 35.0 31.6 34.4 31.3 13.3 19.2 20.6 22.5 18.4 6.4 21.2 17.9 13.6 41.6 16.2 13.5 5.1 10.0 18.9 27.6 58.4 17.1 22.3 23.3 13.7 14.4 1.0 22.9 14.8 16.0 20.9 7.6 23.9 10.5 11.4 17.4 9.7 13.9 24.7 15.0 17.2 5.8 17.9 23.5 20.8 16.0 28.5 13.3 8.5 4.7 23.3 13.0 14.2 13.1 19.8 26.7 30.9 11.1 9.4 17.5 16.2 28.6 15.7 19.9 23.3 11.9 30.6 69.2 26.3 15.8 15.2 9.1 17.5 18.2 7.7 8.3 16.0 15.0 14.0 22.6 FAM228A "C2orf84, FLJ30851" ENSG00000186453 "Family with sequence similarity 228 member A" Q86W67 2 24175053-24200849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 35.1" "Group enriched" "Detected in some" 5 "Early spermatids: 119.7;Spermatocytes: 176.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.5;hTERT-RPE1: 1.1;TIME: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075817 Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA075817: " "unprognostic (2.57e-1)" "unprognostic (7.14e-2)" "unprognostic (2.92e-2)" "unprognostic (1.98e-3)" "unprognostic (7.13e-4)" "unprognostic (2.19e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (9.57e-2)" "unprognostic (2.14e-1)" "unprognostic (4.44e-5)" "unprognostic (1.73e-2)" "unprognostic (1.04e-4)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (2.30e-1)" "unprognostic (1.33e-2)" 2.0 0.9 1.9 0.6 1.7 0.0 1.6 1.4 2.8 0.9 0.0 0.9 0.3 0.7 0.9 0.9 0.6 1.1 1.7 1.3 1.0 0.8 0.3 0.8 0.6 0.8 0.7 0.7 0.3 0.1 0.4 1.0 0.8 0.8 0.3 0.9 0.2 0.9 0.4 0.4 0.4 0.5 0.2 0.4 0.7 35.1 0.7 0.3 0.6 0.4 0.2 0.9 0.5 1.9 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.2 0.2 0.0 0.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.1 1.9 1.7 1.4 2.8 1.3 1.0 0.8 0.7 0.8 0.2 0.7 1.9 0.4 3.2 0.5 3.3 0.0 0.5 0.1 0.0 0.0 0.4 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.7 119.7 0.0 0.4 0.5 0.0 0.0 5.5 0.5 0.2 1.6 0.0 0.0 0.0 0.6 1.1 0.1 0.5 1.7 5.8 0.0 0.0 0.8 0.4 24.8 2.8 0.3 0.0 2.8 0.1 0.3 1.0 3.0 3.1 0.7 0.0 4.5 0.0 0.1 0.0 0.0 0.1 0.2 6.6 1.0 0.8 176.0 10.4 0.0 0.1 0.1 0.1 0.5 0.0 0.2 FAM234A "C16orf9, DKFZP761D0211, FLJ32603, ITFG3" ENSG00000167930 "Family with sequence similarity 234 member A" Q9H0X4 16 234521-272183 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011651, HPA071871" Uncertain Uncertain Nucleoplasm,Mitochondria NA NA 5300000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA011651: , HPA071871: AB_2732188" "unprognostic (1.00e-1)" "unprognostic (1.85e-2)" "unprognostic (3.49e-1)" "unprognostic (4.80e-2)" "unprognostic (5.51e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.93e-1)" "unprognostic (2.21e-2)" "unprognostic (7.52e-2)" "unprognostic (1.16e-1)" "unprognostic (3.28e-2)" "unprognostic (2.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (3.68e-1)" 59.5 57.9 22.5 25.1 38.7 19.9 46.5 41.1 30.5 38.3 41.3 71.2 101.2 52.5 21.5 59.7 40.8 37.6 116.8 21.9 25.7 57.7 51.5 36.6 19.2 59.0 37.2 39.5 68.4 48.2 58.1 38.6 54.8 52.5 30.1 9.8 41.2 39.4 175.7 49.1 64.7 40.6 35.7 30.2 59.8 45.1 37.1 16.7 50.5 77.0 15.0 60.1 38.3 71.1 29.5 67.1 72.3 152.1 110.2 66.3 39.2 71.5 92.7 41.9 54.2 67.6 76.9 30.2 104.2 90.8 37.3 55.2 27.6 48.4 35.7 40.5 48.5 35.7 38.8 53.2 81.0 21.4 22.5 74.4 58.7 67.1 48.1 119.8 74.1 39.1 42.1 6.0 44.9 140.0 22.1 25.2 89.1 44.2 31.1 66.5 48.0 120.5 73.9 29.6 83.1 73.9 107.9 58.3 61.5 63.3 81.5 31.4 63.3 76.7 25.2 43.8 21.3 15.6 7.1 37.6 54.4 30.1 104.9 11.7 17.7 13.3 10.1 17.7 5.2 7.1 8.9 10.0 18.0 9.5 10.0 11.3 6.1 15.8 17.2 6.5 9.4 13.9 22.5 38.7 41.1 30.5 21.9 25.7 59.0 37.2 54.8 35.7 37.1 71.1 20.2 9.6 12.6 0.0 7.4 0.0 11.3 0.0 9.6 8.9 23.9 19.7 0.0 21.5 5.0 31.3 25.0 58.7 8.8 25.2 7.9 49.4 27.9 22.2 26.8 18.1 35.2 14.5 0.0 26.1 48.8 21.0 23.4 33.2 8.8 59.2 22.9 23.5 25.7 10.1 0.0 26.4 0.0 14.4 0.0 78.1 16.8 10.9 0.0 0.0 39.6 11.1 10.3 0.0 0.0 18.4 41.5 21.8 5.7 14.8 102.1 18.6 6.6 12.0 19.7 16.9 20.1 29.2 30.8 18.2 0.0 66.2 6.8 73.3 40.4 10.7 FAM240C ENSG00000216921 "Family with sequence similarity 240 member C" A0A1B0GVR7 2 241893988-241902551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "tongue: 225.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.5;REH: 2.4;SCLC-21H: 1.6" HPA073342 Approved Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" Nucleoplasm "HPA073342: " "unprognostic (9.31e-2)" "unprognostic (4.59e-2)" "unprognostic (1.61e-2)" "unprognostic (1.10e-1)" "unprognostic (7.48e-2)" "unprognostic (3.12e-1)" "unprognostic (2.93e-2)" "unprognostic (4.75e-2)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (2.04e-2)" "unprognostic (5.12e-2)" "unprognostic (5.44e-2)" "unprognostic (8.45e-2)" "unprognostic (2.44e-1)" "unprognostic (3.29e-1)" 3.5 0.7 5.9 0.1 6.9 0.3 3.9 6.4 8.2 1.4 5.6 0.2 0.2 1.9 0.0 4.0 1.7 0.1 1.3 5.4 5.9 0.1 0.2 0.1 0.4 6.2 6.4 1.6 36.8 0.5 0.4 0.2 6.4 3.5 0.0 0.6 5.4 3.9 10.2 3.1 0.2 0.1 5.6 0.3 0.4 1.3 6.3 3.4 6.9 225.1 0.2 0.4 1.0 5.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.2 0.0 0.7 0.5 0.0 0.2 0.0 0.0 2.4 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.9 6.4 8.2 5.4 5.9 6.2 6.4 6.4 5.6 6.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 272.0;Alveolar cells type 1: 60.9;Alveolar cells type 2: 69.9;Breast glandular cells: 87.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 41.3;HUVEC TERT2: 28.0" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" 16.7 4.1 7.7 5.3 8.6 7.2 11.2 16.6 15.5 2.8 0.5 2.8 2.9 3.8 3.8 4.3 2.3 5.1 7.2 6.7 1.7 4.5 4.6 5.1 5.2 1.6 2.3 2.8 2.2 3.9 1.5 10.8 2.9 3.8 2.8 10.5 8.8 2.9 6.0 6.3 3.4 5.1 0.4 5.0 7.3 6.0 3.9 3.2 4.2 5.0 4.1 5.1 2.5 13.7 6.3 2.4 2.5 2.1 12.5 7.1 3.7 5.3 1.2 1.0 1.6 1.9 7.9 41.3 4.9 2.9 3.5 3.1 3.9 5.5 1.8 19.7 6.6 4.4 6.4 3.4 7.4 10.3 2.7 7.8 8.7 1.5 9.1 2.0 28.0 5.8 8.4 19.6 3.1 6.5 3.8 7.4 3.2 10.3 5.9 8.6 4.2 8.5 4.2 6.1 4.6 3.8 5.0 9.0 2.7 3.6 6.5 4.4 17.9 3.2 9.7 2.1 1.9 8.2 11.3 19.1 7.3 5.1 4.1 2.8 0.6 0.6 0.5 0.5 0.4 0.6 0.5 0.4 0.3 0.9 0.5 0.6 1.5 0.6 0.6 1.0 0.6 0.3 7.7 8.6 16.6 15.5 6.7 1.7 1.6 2.3 2.9 0.4 3.9 13.7 272.0 60.9 69.9 0.0 4.9 0.0 0.0 0.0 0.0 0.0 87.0 42.2 0.0 0.0 36.5 33.1 0.0 1.6 9.2 0.0 7.9 12.0 0.0 4.6 3.9 44.0 0.0 0.0 0.0 17.3 2.8 13.8 0.0 12.0 32.8 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 28.2 0.0 0.0 4.0 0.0 0.0 3.5 42.3 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 2.5 9.8 1.3 0.0 0.0 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 142.6;pancreas: 212.3;salivary gland: 119.4;stomach 1: 114.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 304.6;Exocrine glandular cells: 399.9;Proximal enterocytes: 831.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in some" "CACO-2: 19.5;CAPAN-2: 11.7;Hep G2: 32.1;OE19: 27.3;RPMI-8226: 80.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" NA NA 2080000 250000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 1.5 0.1 0.0 2.5 0.1 0.8 17.7 0.1 0.3 4.9 1.3 5.9 142.6 0.3 22.1 56.2 17.2 16.2 0.6 0.1 0.1 17.9 2.6 9.3 1.5 0.1 0.1 0.2 212.3 0.5 5.4 15.2 0.1 37.9 0.1 0.0 119.4 8.7 0.1 2.3 135.0 0.5 0.1 0.6 114.9 6.9 0.1 3.1 8.0 0.0 16.8 34.4 16.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 19.5 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.9 27.3 0.0 0.2 0.0 80.6 0.0 5.8 0.4 0.4 0.0 0.7 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 1.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 22.4 25.7 0.0 0.8 1.3 17.0 2.9 1.2 0.0 101.3 123.1 0.2 102.9 36.5 66.2 0.0 304.6 1.4 2.7 25.4 172.1 25.2 0.2 0.1 2.5 0.0 0.0 0.1 399.9 11.1 3.4 147.3 0.7 1.3 0.6 0.4 0.3 27.0 0.0 0.1 120.9 42.7 5.0 15.8 11.5 0.6 3.9 5.4 1.9 2.1 0.0 0.0 0.0 0.1 144.6 169.0 0.4 0.2 64.9 831.6 0.7 22.4 0.0 0.0 0.4 1.8 28.0 8.1 29.1 1.3 161.3 0.9 0.0 125.2 130.5 FAM53B "bA12J10.2, KIAA0140, smp" ENSG00000189319 "Family with sequence similarity 53 member B" Q14153 10 124619292-124744378 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037751, HPA037752" Approved Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA037751: AB_2675645, HPA037752: AB_10672285" "unprognostic (7.88e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.73e-2)" "unprognostic (2.92e-1)" "unprognostic (4.91e-1)" "prognostic favorable (1.97e-4)" "unprognostic (2.52e-2)" "unprognostic (5.03e-3)" "unprognostic (1.51e-2)" "unprognostic (4.02e-2)" "prognostic favorable (7.00e-6)" "unprognostic (1.93e-1)" "prognostic favorable (4.81e-7)" "prognostic favorable (3.26e-4)" "unprognostic (3.41e-1)" "unprognostic (2.03e-1)" "unprognostic (2.45e-2)" 12.6 19.2 21.6 14.3 33.3 25.8 8.3 18.1 30.5 12.8 8.4 12.4 15.4 23.6 3.9 13.2 11.2 5.7 18.9 21.1 16.5 10.6 4.2 10.7 31.0 30.3 25.6 19.1 7.2 12.4 12.7 4.9 22.7 8.9 7.1 6.3 15.2 7.0 55.0 14.4 17.1 12.8 17.3 20.1 9.6 15.6 35.9 32.9 16.2 22.3 21.7 8.6 8.0 51.7 10.7 12.5 9.6 27.5 11.3 5.8 26.2 4.8 6.7 5.6 4.9 6.6 6.7 37.2 9.7 6.5 5.5 20.8 12.7 15.4 2.4 44.6 13.2 18.1 6.3 16.7 7.6 16.6 11.8 5.6 16.2 5.2 8.3 7.0 9.1 21.2 13.2 17.0 5.5 20.4 18.7 22.4 5.9 9.5 10.9 32.9 3.6 18.2 4.6 19.3 12.8 12.2 4.7 17.8 60.2 3.8 7.2 21.8 5.0 6.7 5.5 6.6 10.7 2.7 5.3 23.8 5.1 13.6 3.8 0.8 2.2 2.2 6.9 2.1 3.3 3.5 3.0 3.7 1.4 6.0 1.2 2.0 3.2 0.7 2.6 1.9 3.6 3.4 21.6 33.3 18.1 30.5 21.1 16.5 30.3 25.6 22.7 17.3 35.9 51.7 13.4 9.6 12.6 14.0 22.4 3.6 5.9 8.5 12.5 6.1 4.3 2.4 17.9 1.5 6.7 3.7 10.4 4.7 31.5 25.9 1.9 3.1 19.4 12.9 18.6 8.7 15.0 8.6 27.1 4.0 4.9 6.0 6.6 8.3 5.1 9.0 16.8 3.7 13.3 1.7 15.0 17.4 10.2 27.8 5.1 6.2 5.6 16.4 8.8 24.4 14.5 4.5 30.9 16.1 79.4 2.8 12.2 10.5 20.0 3.7 22.4 4.3 14.1 25.6 0.0 9.8 4.6 7.0 8.6 12.1 5.7 0.8 21.4 6.9 15.3 6.7 FAM89A "C1orf153, MGC15887" ENSG00000182118 "Family with sequence similarity 89 member A" Q96GI7 1 231018958-231040254 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.0;placenta: 68.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 186.3;Extravillous trophoblasts: 267.5;Rod photoreceptor cells: 102.5;Syncytiotrophoblasts: 278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 145.4;SK-MEL-30: 81.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059052, HPA059578" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles" Nucleoplasm "HPA059052: AB_2683890, HPA059578: AB_2684070" "unprognostic (7.80e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-3)" "unprognostic (1.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.10e-1)" "unprognostic (8.05e-3)" "unprognostic (4.85e-1)" "unprognostic (1.54e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.87e-2)" "unprognostic (2.03e-1)" "unprognostic (2.01e-1)" "unprognostic (9.26e-2)" 60.0 18.0 16.0 4.8 15.3 5.9 36.5 20.7 16.4 11.0 21.3 4.4 1.7 7.5 1.6 6.5 7.1 5.9 10.6 14.2 23.4 22.2 9.2 19.2 5.9 22.6 21.4 6.0 10.6 6.0 5.8 68.2 20.9 7.1 2.7 17.3 5.3 4.6 5.9 30.6 4.6 4.1 21.2 17.5 7.6 3.0 25.1 2.9 5.5 6.7 4.7 8.9 9.2 19.5 0.9 13.7 6.3 13.4 15.0 3.0 145.4 7.8 5.8 2.8 5.1 21.1 12.1 0.0 1.8 5.1 16.7 8.4 12.0 1.9 2.3 42.4 28.9 6.7 0.3 0.9 57.6 5.0 35.2 50.1 26.6 0.0 13.2 0.1 7.4 15.0 53.4 8.6 2.7 5.0 3.2 8.8 9.4 12.6 4.3 16.6 20.3 16.0 10.1 14.8 5.8 16.1 2.6 1.2 81.6 13.9 0.8 29.2 1.1 22.5 0.1 0.4 14.7 18.3 23.7 11.6 6.7 9.8 45.7 1.4 0.2 0.0 0.2 0.0 0.3 0.3 0.2 0.5 0.0 0.1 0.4 0.9 0.0 0.1 0.0 0.0 0.0 0.2 16.0 15.3 20.7 16.4 14.2 23.4 22.6 21.4 20.9 21.2 25.1 19.5 82.3 0.0 2.6 3.6 4.2 30.1 22.0 0.3 8.0 48.1 3.8 5.2 3.3 7.2 0.7 0.0 77.2 186.3 4.9 0.3 3.9 2.8 1.3 1.3 39.3 44.5 0.0 14.9 1.1 3.3 267.5 11.6 0.5 2.6 4.5 0.5 10.8 11.1 51.0 8.4 10.8 0.6 0.0 19.6 2.1 3.6 2.8 8.5 21.4 22.5 0.5 26.2 1.0 10.1 2.0 4.4 0.5 1.5 1.4 30.2 0.0 5.1 0.1 102.5 0.0 9.9 8.5 4.2 11.6 1.7 32.8 278.3 5.5 0.4 1.3 15.4 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 14 "dendritic cells: 43.4;NK-cells: 79.3;T-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" 0.3 0.8 0.1 1.0 0.2 2.8 0.6 0.1 0.2 0.4 0.1 0.8 1.9 0.5 0.7 0.3 0.3 1.1 0.3 0.2 0.1 0.3 1.1 2.0 5.7 0.3 0.2 0.3 0.1 0.0 0.1 0.2 0.2 0.5 0.9 0.0 0.9 0.3 0.1 0.4 1.4 0.3 0.0 4.1 1.5 0.2 0.1 0.6 0.2 0.0 1.8 0.8 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 58.1 0.2 35.5 0.0 11.5 31.4 0.1 0.0 2.2 25.0 1.9 41.5 0.1 0.0 0.2 14.9 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.4 0.4 0.0 2.5 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 43.4 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.6 1.8 0.0 0.9 0.0 79.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 28.8 0.0 0.0 0.1 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 119.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 285.7;LHCN-M2: 206.7" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" NA NA 4600000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" 20.1 1.3 14.5 7.2 20.2 0.8 21.9 31.1 12.4 20.0 119.2 35.0 25.9 23.4 16.0 13.3 9.8 23.5 24.8 14.3 27.0 22.1 10.0 12.9 2.4 40.1 42.3 10.4 12.6 11.4 9.7 17.0 24.4 21.4 31.4 3.4 18.7 24.2 3.5 17.5 24.2 25.7 22.1 2.2 16.8 9.7 22.2 6.0 14.6 3.9 4.4 32.0 11.0 22.0 22.2 83.5 80.9 0.3 79.1 94.5 19.9 110.9 181.9 52.8 33.5 50.0 49.0 0.0 26.0 285.7 34.1 40.4 32.0 136.7 71.6 0.2 13.2 0.0 30.5 50.8 39.4 37.3 29.2 34.5 48.4 98.7 63.5 72.4 1.1 44.8 0.6 0.0 206.7 27.1 66.2 0.1 18.1 42.2 13.9 0.3 22.3 1.8 79.2 79.0 8.6 32.3 19.2 32.2 12.7 54.9 0.3 13.3 23.8 149.8 57.9 2.0 69.8 0.4 0.2 0.5 34.1 0.1 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 20.2 31.1 12.4 14.3 27.0 40.1 42.3 24.4 22.1 22.2 22.0 6.1 16.0 6.7 55.2 0.3 85.0 27.2 115.4 27.3 5.2 26.5 27.6 27.6 38.6 40.7 53.3 0.0 1.6 0.2 71.2 5.9 25.2 0.7 25.7 17.2 5.0 14.5 0.0 5.8 26.5 3.6 28.8 54.0 29.6 16.5 75.0 1.1 26.1 0.4 0.0 30.3 56.4 18.3 0.8 7.3 0.9 14.6 1.7 12.4 5.6 0.0 4.5 0.0 14.1 12.4 30.3 30.0 37.2 0.2 55.8 78.2 26.7 37.0 0.4 39.5 23.1 65.1 1.5 10.4 10.2 46.9 1.6 1.9 11.7 45.1 38.9 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 324.4;kidney: 297.8;liver: 893.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 500.4;Macrophages: 238.6;Proximal enterocytes: 1095.0;Proximal tubular cells: 864.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 404.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HaCaT: 75.2;MCF7: 243.4;OE19: 54.5;RT4: 157.0;U-698: 170.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 21000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favorable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favorable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.64e-5)" 13.7 27.4 1.6 12.7 1.8 15.0 41.4 1.8 5.7 19.9 2.6 29.8 324.4 3.6 15.8 2.7 7.1 34.4 2.9 1.5 2.2 297.8 893.2 165.9 6.8 3.6 2.6 1.1 41.4 107.9 8.6 3.0 2.9 25.8 30.5 0.7 53.2 28.9 1.3 8.1 258.1 8.8 2.6 12.2 85.6 2.5 3.2 2.2 16.8 0.9 7.8 70.8 6.7 3.8 0.5 0.1 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.6 3.8 0.0 0.3 0.8 0.1 75.2 0.1 0.0 0.1 0.0 0.3 0.6 2.9 1.3 0.0 1.5 18.8 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.2 0.3 0.2 243.4 0.1 4.4 1.1 54.5 9.5 0.0 0.9 1.9 0.0 157.0 0.7 5.6 0.6 44.5 0.0 0.9 26.7 7.7 0.2 0.1 1.0 0.8 0.0 0.3 1.1 170.4 0.0 1.4 0.1 63.3 68.4 404.3 7.9 162.3 11.7 3.0 4.6 4.6 90.1 3.2 16.2 8.3 12.1 15.4 90.7 32.1 2.3 33.1 1.6 1.8 1.8 5.7 1.5 2.2 3.6 2.6 2.9 2.6 3.2 3.8 2.8 76.9 182.8 0.0 10.3 0.8 8.9 0.7 0.0 0.1 62.4 24.3 0.7 102.9 41.0 62.5 0.0 11.1 14.8 26.1 111.6 21.5 0.1 4.0 0.4 4.8 31.9 24.4 0.9 62.7 1.7 5.4 102.4 5.2 47.4 16.0 12.1 500.4 177.6 0.0 0.8 61.4 0.0 79.9 32.1 1.5 1.5 238.6 12.4 1.9 20.1 2.6 8.2 0.5 0.3 24.0 77.6 4.1 18.3 11.9 1095.0 864.1 9.1 0.2 6.6 0.6 2.0 0.6 1.3 0.8 1.0 10.1 12.1 0.5 90.4 68.1 FBXL7 "FBL6, FBL7, KIAA0840" ENSG00000183580 "F-box and leucine rich repeat protein 7" Q9UJT9 5 15500180-15939795 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 976.2;Inhibitory neurons: 295.1;Oligodendrocyte precursor cells: 335.8;Oligodendrocytes: 766.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA055464 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055464: AB_2682822" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" "unprognostic (3.34e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (4.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.41e-2)" "unprognostic (4.29e-3)" "unprognostic (3.42e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.69e-4)" "unprognostic (1.94e-3)" 17.5 22.7 16.9 3.7 19.5 0.0 13.9 16.0 15.9 19.1 15.9 17.2 2.0 26.4 10.3 9.7 15.8 8.4 17.0 15.5 14.2 4.7 2.1 9.6 2.6 19.7 16.5 26.8 1.9 1.0 4.7 6.6 16.1 13.3 5.2 4.3 5.6 19.5 4.0 5.0 6.8 24.6 15.1 5.0 10.2 4.4 18.4 2.4 8.2 5.7 2.1 16.6 13.1 22.3 0.1 1.4 16.1 23.5 13.1 10.0 0.0 14.1 17.0 9.9 10.3 0.0 0.0 0.0 0.0 21.7 10.2 0.0 8.1 5.2 9.8 0.0 1.1 0.0 0.0 0.0 5.1 0.0 0.0 11.8 0.0 8.0 0.7 12.1 23.2 0.0 0.0 6.1 7.5 0.0 0.0 0.0 5.4 0.0 2.6 0.0 11.4 0.1 0.0 0.0 4.7 15.9 0.0 4.9 15.3 14.5 0.0 0.0 22.9 20.6 4.1 11.7 6.3 0.0 0.0 0.0 11.4 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 19.5 16.0 15.9 15.5 14.2 19.7 16.5 16.1 15.1 18.4 22.3 21.4 3.2 1.9 976.2 0.3 2.4 2.7 2.4 2.2 3.2 0.9 1.1 11.8 0.0 1.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 2.0 11.8 16.7 0.0 0.0 3.7 0.0 0.1 15.9 0.0 2.0 1.3 13.1 15.4 0.2 0.8 30.3 295.1 0.0 0.0 0.6 2.7 0.7 30.1 0.5 5.4 146.1 0.0 2.4 0.0 335.8 766.0 0.0 0.0 41.3 1.2 3.1 0.0 1.2 3.8 2.5 6.6 16.1 8.1 1.4 2.1 1.5 1.7 0.0 0.3 20.7 0.0 2.4 FBXO27 "Fbg5, Fbx27" ENSG00000161243 "F-box protein 27" Q8NI29 19 38990714-39032785 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 37.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Suprabasal keratinocytes: 17.8;Syncytiotrophoblasts: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 35.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA046800, HPA062242" Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA046800: AB_2679813, HPA062242: AB_2684723" "prognostic favorable (2.15e-4)" "unprognostic (7.32e-2)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (1.48e-3)" "unprognostic (4.38e-3)" "unprognostic (1.02e-1)" "unprognostic (8.95e-2)" "unprognostic (1.67e-1)" "unprognostic (7.31e-3)" "unprognostic (6.80e-2)" "unprognostic (9.31e-2)" "unprognostic (2.25e-2)" "unprognostic (8.72e-3)" "unprognostic (6.04e-2)" "unprognostic (7.51e-2)" "unprognostic (3.21e-2)" 13.3 3.7 17.5 2.1 15.9 2.7 6.2 23.8 18.7 6.3 6.4 6.8 2.2 4.7 2.4 15.4 5.3 5.5 19.6 15.4 8.9 6.4 7.5 3.2 3.7 10.7 6.7 10.2 4.8 2.5 4.1 3.8 9.1 8.9 8.7 4.9 7.4 7.8 1.6 37.5 4.9 7.4 4.9 3.1 3.8 4.7 11.1 4.0 4.6 2.4 4.0 7.7 9.7 13.1 9.1 11.4 0.3 7.2 15.3 0.8 3.3 1.2 6.7 5.2 4.9 3.8 3.4 0.9 17.5 10.3 9.0 15.5 0.6 6.6 3.4 0.8 0.4 0.3 3.0 0.6 2.7 0.9 2.5 5.5 10.2 5.4 0.4 8.2 3.3 0.4 5.4 1.2 7.2 8.1 0.6 1.4 8.1 3.0 20.4 0.2 0.1 1.1 3.4 35.3 0.4 10.8 17.7 2.2 0.1 4.8 9.2 1.7 4.0 0.5 0.4 0.3 0.9 3.5 8.9 1.9 9.0 0.2 0.3 1.1 0.3 0.2 0.3 0.3 0.2 0.4 0.2 0.2 0.2 0.6 0.4 0.3 1.7 1.7 0.2 0.5 0.3 0.2 17.5 15.9 23.8 18.7 15.4 8.9 10.7 6.7 9.1 4.9 11.1 13.1 0.2 3.2 15.0 2.3 0.1 5.9 4.1 1.4 9.1 7.5 3.8 4.2 9.5 7.2 6.4 1.8 0.0 36.1 0.5 0.2 1.9 1.5 3.7 1.9 3.6 3.2 0.0 0.0 4.8 0.8 4.8 2.7 6.1 1.6 7.6 2.3 1.4 3.2 4.9 8.4 4.6 0.2 8.2 0.3 4.9 2.5 2.8 2.1 0.0 1.0 1.1 5.6 0.0 3.0 4.1 0.3 0.0 4.1 1.9 2.3 6.9 7.3 4.7 3.0 0.0 1.8 1.5 6.4 2.0 13.5 17.8 27.0 1.3 0.4 0.2 5.3 FBXW4 "dactylin, Fbw4, SHFM3" ENSG00000107829 "F-box and WD repeat domain containing 4" P57775 10 101610664-101695295 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043496 Approved Approved "Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA043496: AB_2678514" "unprognostic (4.31e-2)" "unprognostic (5.43e-3)" "unprognostic (8.40e-3)" "prognostic favorable (4.91e-4)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (9.96e-3)" "unprognostic (1.87e-1)" "unprognostic (3.96e-1)" "prognostic favorable (4.67e-4)" "unprognostic (1.13e-2)" "prognostic favorable (3.41e-5)" "unprognostic (2.94e-3)" "unprognostic (1.81e-1)" "unprognostic (4.99e-2)" "unprognostic (1.85e-2)" 38.4 30.4 89.9 10.4 96.6 16.0 34.8 83.5 96.3 33.2 71.3 59.9 16.5 26.7 29.6 38.7 28.9 12.9 62.4 80.9 81.1 36.4 34.9 35.8 18.0 92.3 92.1 30.2 44.2 47.0 46.7 16.4 87.8 49.1 16.5 14.2 41.4 26.8 80.0 49.7 31.5 14.7 94.8 30.1 40.8 22.8 94.2 18.1 40.2 44.4 17.9 49.0 32.9 98.0 22.1 25.7 4.0 28.9 20.1 16.5 18.9 11.3 31.1 12.8 10.0 12.0 22.9 25.1 17.5 23.4 13.1 13.4 11.0 16.7 4.3 26.8 15.2 6.0 9.1 26.1 35.7 10.0 7.6 15.2 52.0 6.9 42.8 29.8 11.0 17.6 6.2 15.3 14.2 45.9 11.4 14.2 11.3 11.4 12.3 9.4 29.6 10.7 25.1 14.7 12.3 21.6 21.8 8.1 20.7 6.0 33.6 17.8 11.8 13.8 1.8 5.8 11.5 31.9 15.4 11.1 11.3 12.7 8.1 1.3 1.4 2.2 4.3 0.8 2.6 3.8 4.3 4.2 1.1 4.8 4.5 3.7 0.2 4.2 1.4 4.1 1.4 1.2 89.9 96.6 83.5 96.3 80.9 81.1 92.3 92.1 87.8 94.8 94.2 98.0 13.6 3.2 36.9 45.4 14.0 11.2 16.4 11.9 6.8 28.5 25.7 21.8 35.8 12.8 11.1 11.0 18.8 17.0 24.4 29.1 3.9 15.2 50.2 15.3 16.3 10.0 20.4 7.0 57.5 26.1 9.2 11.3 17.3 27.2 5.1 32.3 8.9 24.7 8.8 37.0 55.7 27.8 14.2 8.6 7.4 28.9 14.3 8.7 14.2 55.3 10.7 29.9 15.5 54.8 70.3 19.4 24.4 17.0 14.1 22.2 21.1 13.3 7.5 22.7 13.1 15.4 14.7 4.9 6.0 11.3 12.5 15.6 16.9 10.9 21.7 18.7 FBXW5 "DKFZP434B205, Fbw5, MGC20962" ENSG00000159069 "F-box and WD repeat domain containing 5" Q969U6 9 136940435-136944738 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 251.8" "Cell type enhanced" "Detected in all" "Early spermatids: 581.9;Late spermatids: 1900.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046615 Approved Approved Mitochondria No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA046615: AB_10965648" "unprognostic (1.11e-1)" "unprognostic (1.10e-2)" "unprognostic (1.56e-2)" "prognostic favorable (1.02e-4)" "unprognostic (4.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-2)" "unprognostic (7.16e-3)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (3.51e-3)" "unprognostic (3.23e-2)" "prognostic favorable (4.74e-4)" "unprognostic (1.73e-2)" "unprognostic (3.64e-1)" "unprognostic (2.32e-1)" "unprognostic (2.13e-1)" 54.7 58.1 27.6 23.3 23.0 28.7 47.4 23.4 32.4 36.2 23.4 73.9 42.9 44.1 9.4 70.8 33.9 17.7 117.1 34.7 23.5 54.3 132.4 37.5 22.1 27.0 27.2 29.1 75.7 19.0 41.1 15.5 28.3 56.3 13.4 3.9 54.8 26.9 188.7 42.6 59.3 17.2 24.3 47.6 65.0 251.8 33.0 24.7 42.5 66.0 17.6 59.4 41.5 23.7 39.2 65.5 14.9 36.7 36.6 23.6 85.7 40.6 27.5 27.7 15.3 42.9 48.8 27.0 46.0 42.0 21.5 48.0 13.6 35.3 4.6 35.4 47.2 22.9 88.8 46.8 40.0 34.2 55.2 26.9 31.0 25.4 21.1 21.9 28.9 19.5 46.0 42.7 21.3 98.3 26.2 36.4 26.7 48.1 70.6 28.7 22.5 46.3 24.5 37.9 30.9 30.0 49.0 52.8 54.4 5.7 60.3 52.4 55.8 39.5 35.1 75.1 35.1 33.6 45.1 17.0 55.0 29.7 30.5 62.8 62.1 88.0 97.7 74.3 75.3 39.2 73.9 83.3 59.6 31.1 32.0 53.7 32.9 55.4 61.2 98.8 96.8 72.8 27.6 23.0 23.4 32.4 34.7 23.5 27.0 27.2 28.3 24.3 33.0 23.7 61.3 19.2 45.4 13.1 40.7 28.7 44.5 129.0 26.7 29.9 50.1 48.8 86.9 50.1 72.8 23.9 16.7 68.3 108.0 336.5 74.3 111.7 581.9 29.1 27.5 53.6 67.3 36.8 15.9 148.1 132.9 38.9 98.4 38.6 28.6 116.2 46.1 113.3 88.0 60.6 15.3 153.7 65.1 62.6 49.3 1900.7 51.6 69.2 69.4 8.4 124.9 59.1 83.4 11.1 17.1 132.5 238.0 71.1 59.4 84.6 420.9 134.1 43.5 37.3 59.2 33.5 59.0 224.3 47.4 47.1 35.9 101.4 66.6 49.4 127.6 70.0 FCER1G ENSG00000158869 "Fc fragment of IgE receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.6;lymphoid tissue: 470.1" "Group enriched" "Detected in many" 9 "dendritic cells: 726.6;granulocytes: 705.6;Hofbauer cells: 2318.6;Kupffer cells: 1950.8;Langerhans cells: 1526.3;Macrophages: 1971.3;monocytes: 808.9;NK-cells: 1037.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 1987.3;classical monocyte: 3240.2;intermediate monocyte: 5333.6;myeloid DC: 2386.3;neutrophil: 1831.0;NK-cell: 1750.9;non-classical monocyte: 6984.5;plasmacytoid DC: 3315.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "HEL: 77.8;HMC-1: 301.7;THP-1: 276.1;U-266/84: 90.1;U-937: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" 251.7 86.5 34.0 275.6 33.8 441.6 62.9 35.5 66.0 52.5 47.5 82.7 44.9 30.7 38.7 30.6 72.0 101.5 53.1 33.7 42.0 40.3 177.3 286.6 160.9 53.4 48.7 19.9 22.3 26.8 26.9 211.0 50.1 31.0 113.2 8.3 42.9 38.8 11.9 21.0 60.6 160.3 41.5 470.1 39.4 14.5 49.9 62.7 25.5 34.6 82.5 254.6 21.7 65.4 0.2 0.0 0.7 1.3 1.8 0.7 0.4 0.5 0.2 0.5 0.8 2.2 0.1 0.5 0.7 0.0 0.3 0.2 0.5 0.0 0.4 0.3 1.5 77.8 0.6 14.0 0.3 16.1 301.7 6.0 3.3 2.3 0.2 0.7 0.4 1.8 0.1 7.3 2.4 0.5 1.4 37.9 1.6 0.0 0.0 0.1 6.7 0.2 0.5 0.4 0.3 1.0 0.6 0.1 2.7 1.4 0.2 276.1 0.4 1.8 0.4 0.9 1.1 3.0 90.1 0.9 1.7 87.1 0.5 1987.3 3240.2 307.3 13.6 5333.6 15.9 28.2 10.6 10.6 2386.3 9.0 17.3 45.0 1831.0 1750.9 6984.5 3315.6 21.8 4265.5 34.0 33.8 35.5 66.0 33.7 42.0 53.4 48.7 50.1 41.5 49.9 65.4 12.8 86.6 147.7 0.7 35.9 39.6 1.5 0.2 1.8 0.1 5.2 22.1 6.8 15.7 27.3 18.4 0.0 14.5 726.6 1.0 0.0 1.9 3.0 1.0 0.9 38.6 1.8 79.3 0.1 1.0 18.8 18.3 1.1 1.0 705.6 0.5 41.0 13.6 2318.6 0.0 0.2 0.5 0.0 1950.8 1526.3 9.4 5.3 1971.3 80.0 12.2 808.9 0.2 1037.1 0.0 0.1 1.0 1.4 1.2 10.1 1.3 0.4 5.4 15.3 2.3 72.3 3.8 11.2 1.0 2.5 1.4 35.9 23.7 133.3 0.4 0.6 1.8 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 75.0;Hepatic stellate cells: 333.8;Langerhans cells: 244.0;Macrophages: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 24.9;HMC-1: 31.2;NB-4: 7.3;RPMI-8226: 11.7" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" 30.4 7.5 0.9 12.2 1.3 1.7 15.4 1.3 3.3 9.7 4.2 10.3 3.0 2.6 2.8 11.4 4.4 13.0 7.9 0.7 1.1 4.2 42.4 21.7 15.8 4.5 1.1 4.8 4.7 2.8 1.4 398.2 2.2 1.8 11.0 1.1 7.0 2.8 2.2 4.8 16.0 16.6 2.2 25.5 4.9 2.5 1.4 7.4 4.2 13.7 29.6 18.7 3.1 5.8 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 7.3 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.8 0.0 327.2 8.5 26.4 1.4 9.7 0.6 202.8 0.7 1.1 72.4 160.4 0.1 1.4 53.6 0.7 9.5 0.1 0.1 13.0 0.9 1.3 1.3 3.3 0.7 1.1 4.5 1.1 2.2 2.2 1.4 5.8 2.2 0.0 3.9 0.0 75.0 5.4 0.1 0.0 0.0 0.0 0.3 0.9 2.1 2.8 1.3 0.0 0.0 0.2 5.6 0.0 0.0 0.0 4.8 0.0 0.0 49.8 0.0 3.2 0.0 0.0 0.2 1.7 1.1 0.0 2.5 0.2 333.8 8.2 7.6 0.0 0.0 0.0 0.0 47.4 244.0 4.2 0.6 145.5 23.2 0.0 9.5 0.0 5.2 0.0 0.1 0.0 0.0 0.0 45.4 0.0 0.0 0.3 0.0 0.0 0.0 1.7 2.5 0.3 0.2 0.7 3.1 0.4 5.8 0.1 0.1 0.0 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 278.3;lung: 724.6" "Cell type enriched" "Detected in some" 16 "Hepatic stellate cells: 2828.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025945 Approved "Secreted to blood" NA NA 22800000000 14000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025945: " "unprognostic (1.59e-1)" "unprognostic (5.25e-2)" "unprognostic (1.55e-2)" "unprognostic (8.27e-2)" "unprognostic (1.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.87e-3)" "unprognostic (1.21e-1)" "unprognostic (6.28e-4)" "unprognostic (7.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-2)" 62.6 35.9 1.1 5.7 1.0 0.0 40.8 1.1 1.6 2.7 10.0 4.1 0.8 3.9 0.1 2.8 3.0 1.6 62.1 1.4 1.1 55.2 278.3 724.6 4.3 1.2 1.2 2.4 12.5 2.7 6.6 22.6 1.2 5.3 0.5 0.0 2.5 0.5 9.0 1.9 6.7 1.8 1.2 11.3 8.4 2.4 1.2 0.4 20.4 7.5 0.3 3.0 1.9 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 1.1 1.6 1.4 1.1 1.2 1.2 1.2 1.2 1.2 1.0 94.1 0.0 9.3 0.0 16.6 0.8 0.6 0.5 0.6 0.0 0.8 2.8 2.4 52.9 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.5 0.4 0.2 155.1 0.0 136.4 0.1 0.0 0.0 3.8 0.5 0.2 3.8 0.0 2828.6 31.8 0.3 0.0 0.1 0.0 2.0 168.6 0.3 2.7 3.4 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.1 5.1 0.0 0.0 1.0 2.7 0.5 0.5 1.0 1.1 0.0 4.9 0.5 0.0 0.3 FCRL2 "CD307b, FCRH2, IRTA4, SPAP1" ENSG00000132704 "Fc receptor like 2" Q96LA5 1 157745733-157777132 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "intestine: 20.9;lymphoid tissue: 34.3" "Group enriched" "Detected in some" 17 "B-cells: 84.7;Plasma cells: 40.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 29.7;naive B-cell: 18.4" "Lineage enriched" "Detected in single" 42 "B-cells: 29.7" "Group enriched" "Detected in some" 4 "Daudi: 12.9;U-698: 10.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (3.94e-3)" "unprognostic (1.47e-3)" "unprognostic (3.49e-2)" "unprognostic (3.69e-3)" "unprognostic (5.11e-5)" "unprognostic (1.67e-2)" "unprognostic (4.77e-3)" "unprognostic (8.19e-2)" "unprognostic (8.66e-3)" "unprognostic (1.20e-2)" "unprognostic (4.19e-2)" "unprognostic (4.60e-7)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (7.92e-2)" "unprognostic (2.48e-1)" 0.4 0.0 0.1 12.3 0.1 2.6 0.4 0.0 0.4 0.2 0.0 2.2 2.2 0.1 0.1 0.4 0.1 1.0 0.4 0.1 0.2 0.4 0.4 0.7 24.1 0.4 0.1 0.4 0.0 0.0 0.0 0.1 0.2 0.3 2.7 0.2 1.0 0.0 0.0 0.2 20.9 0.1 0.1 34.3 1.7 0.3 0.2 1.7 0.5 0.0 25.8 1.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.7 0.0 10.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 29.7 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.4 0.1 0.2 0.4 0.1 0.2 0.1 0.2 0.8 0.0 0.0 1.1 0.0 84.7 0.3 0.5 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.3 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.3 1.3 0.0 0.7 0.6 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 1.0 3.6 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.1 0.0 40.4 0.3 0.0 0.1 0.1 0.0 0.0 1.2 0.6 0.0 0.2 0.0 0.4 0.1 1.9 0.0 0.1 0.4 FCRL3 "CD307c, FCRH3, IFGP3, IRTA3, SPAP2, SPAP2a, SPAP2b, SPAP2c, SPAP2d, SPAP2e" ENSG00000160856 "Fc receptor like 3" Q96P31 1 157674321-157700769 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 49.5" "Cell type enhanced" "Detected in some" "B-cells: 54.3;dendritic cells: 21.2;Early spermatids: 8.0;Late spermatids: 9.1;NK-cells: 30.9;T-cells: 12.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive B-cell: 35.3" "Group enriched" "Detected in many" 54 "B-cells: 35.3;NK-cells: 20.4;T-cells: 19.0" "Cell line enriched" "Detected in some" 7 "Daudi: 9.9" "Low region specificity" "Detected in some" HPA048022 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA048022: AB_2732541" "unprognostic (6.73e-3)" "unprognostic (5.06e-4)" "unprognostic (1.13e-2)" "unprognostic (2.08e-4)" "unprognostic (3.86e-1)" "unprognostic (1.74e-5)" "unprognostic (1.09e-2)" "unprognostic (4.29e-3)" "unprognostic (3.69e-3)" "unprognostic (2.46e-4)" "unprognostic (1.13e-1)" "unprognostic (2.55e-2)" "unprognostic (2.01e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (6.69e-2)" 0.4 0.0 0.0 14.1 0.0 1.1 0.1 0.0 0.0 0.1 0.0 1.1 0.3 0.2 0.1 0.1 0.1 1.0 0.2 0.0 0.0 0.2 0.8 0.9 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.2 0.0 0.8 0.0 0.1 0.0 8.7 0.1 0.0 27.5 1.5 0.2 0.0 4.6 0.4 0.1 36.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 19.0 0.0 1.8 30.3 2.6 13.2 0.0 35.3 0.2 8.3 0.4 20.4 0.0 0.0 11.3 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 54.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.0 1.2 0.0 9.1 0.0 0.4 0.0 1.0 0.9 0.0 30.9 0.5 0.0 0.0 1.1 0.0 3.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 5 "B-cells: 102.6;Early spermatids: 63.6;Plasma cells: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 5 "U-266/70: 3.4;U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" 0.4 0.4 0.0 13.8 0.0 2.3 2.4 0.0 0.1 0.6 0.0 5.5 5.8 0.1 0.3 0.8 0.4 1.2 0.3 0.0 0.0 0.4 0.3 1.1 24.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 4.4 0.0 3.8 0.3 0.0 0.0 5.0 0.1 0.1 15.1 4.5 0.6 0.0 4.1 0.6 0.0 36.3 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 102.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.1 2.9 0.1 0.0 0.0 63.6 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.3 1.1 0.0 1.3 0.0 0.4 1.8 0.3 0.0 0.1 0.0 0.0 0.3 0.3 10.1 0.3 0.2 23.2 0.0 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 190.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.3 1.2 0.1 0.1 0.0 0.7 5.7 0.0 0.6 0.0 FERMT3 "KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2" ENSG00000149781 "Fermitin family member 3" Q86UX7 11 64206678-64223891 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.6;lymphoid tissue: 130.1" "Cell type enhanced" "Detected in many" "dendritic cells: 118.3;granulocytes: 96.4;Hofbauer cells: 193.1;Kupffer cells: 95.8;Langerhans cells: 88.0;Macrophages: 232.9;monocytes: 142.9;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 306.9;HL-60: 135.9;HMC-1: 314.2;Karpas-707: 127.6;MOLT-4: 121.8;NB-4: 174.1;U-937: 138.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065231 Approved Vesicles NA NA 160000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA065231: AB_2685439" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.38e-3)" "prognostic favorable (9.89e-4)" "unprognostic (8.77e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (2.46e-1)" "unprognostic (4.20e-1)" "unprognostic (3.98e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.12e-5)" "unprognostic (3.08e-3)" "unprognostic (5.25e-2)" "unprognostic (4.97e-2)" "unprognostic (1.75e-1)" 25.1 14.5 9.4 63.3 11.6 180.6 13.0 11.2 18.1 8.5 12.2 17.3 22.0 8.4 0.7 6.4 13.6 15.6 12.0 9.8 11.6 11.1 12.5 46.2 89.2 17.9 12.2 5.1 7.0 1.3 5.9 15.0 13.2 8.2 8.1 0.6 10.7 4.4 6.0 7.1 34.1 9.4 13.3 130.1 29.6 4.5 17.1 48.7 10.0 4.6 41.8 19.8 7.3 15.3 1.2 1.6 0.5 0.9 0.3 0.8 2.0 1.4 0.2 0.4 0.3 2.6 2.3 32.6 3.2 6.3 0.7 2.4 1.0 0.5 0.5 83.9 0.6 306.9 1.6 0.1 10.8 135.9 314.2 1.2 1.1 5.2 0.0 0.5 81.2 77.0 7.3 127.6 8.6 3.5 121.8 174.1 1.2 1.0 2.3 72.4 8.8 0.7 0.3 0.7 1.9 0.5 0.7 4.5 1.7 0.7 2.0 92.6 7.8 1.1 2.5 1.9 0.9 1.5 3.3 59.4 19.5 138.9 86.6 204.1 207.0 236.5 120.0 192.6 114.9 54.5 94.1 112.0 162.0 53.1 60.9 80.6 184.6 102.4 151.2 195.7 120.9 292.6 9.4 11.6 11.2 18.1 9.8 11.6 17.9 12.2 13.2 13.3 17.1 15.3 3.8 9.6 14.7 0.7 52.1 4.7 0.9 0.3 3.4 0.5 3.3 5.2 2.4 4.3 3.9 0.0 0.0 1.2 118.3 6.1 0.0 0.8 0.4 4.3 5.6 7.9 0.0 62.5 1.2 2.4 1.4 5.4 19.9 7.3 96.4 0.4 19.6 1.4 193.1 0.0 1.5 32.1 0.0 95.8 88.0 0.9 0.9 232.9 17.8 5.6 142.9 0.3 93.7 1.0 1.5 4.3 10.9 2.6 35.2 0.9 8.2 0.4 1.0 0.3 6.6 13.7 6.6 1.2 0.8 1.9 4.5 2.6 78.5 1.4 15.0 0.7 FEZ2 ENSG00000171055 "Fasciculation and elongation protein zeta 2" Q9UHY8 2 36531805-36646087 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035978 Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Golgi apparatus, Cytosol" "HPA035978: AB_10672235" "unprognostic (1.42e-1)" "unprognostic (5.02e-3)" "unprognostic (2.89e-1)" "unprognostic (1.15e-2)" "unprognostic (2.91e-2)" "unprognostic (1.94e-3)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.65e-2)" "unprognostic (7.82e-3)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" 53.0 39.1 48.2 21.0 51.6 16.5 35.9 48.2 68.6 26.9 42.8 34.5 22.1 33.1 18.9 31.7 23.8 23.6 46.7 49.2 48.4 33.6 29.4 27.1 24.3 49.5 46.3 27.6 10.8 20.3 14.2 46.8 48.2 23.5 27.9 26.5 17.1 32.5 108.1 17.0 28.5 41.1 50.1 30.3 21.9 20.8 49.6 18.2 23.9 78.5 19.5 29.1 24.3 56.3 64.9 37.1 49.4 22.3 91.3 122.1 39.5 157.1 76.5 90.7 56.0 24.6 21.5 39.1 94.7 199.2 41.0 25.1 42.4 54.3 98.5 9.3 24.7 31.7 12.2 43.5 44.4 32.9 8.5 119.9 44.2 57.8 69.6 61.2 131.0 9.5 35.4 12.0 170.2 22.7 19.6 27.5 27.1 33.9 57.8 16.9 44.3 14.0 72.9 57.6 1.9 45.7 38.7 31.9 37.8 51.7 11.3 39.1 161.2 59.7 32.9 33.4 92.9 9.8 11.5 26.6 58.9 22.4 84.8 2.5 3.5 5.1 1.7 3.4 1.0 1.6 1.3 1.0 3.5 1.0 1.5 0.7 4.2 3.2 2.3 15.6 1.4 0.8 48.2 51.6 48.2 68.6 49.2 48.4 49.5 46.3 48.2 50.1 49.6 56.3 109.4 54.5 37.5 25.8 23.7 31.4 94.7 45.5 41.5 52.5 31.7 33.1 43.1 17.2 70.2 58.8 45.9 96.4 61.1 57.6 56.7 80.3 5.6 38.4 44.7 100.9 24.0 15.3 45.4 30.6 87.6 50.7 27.0 64.3 24.1 66.0 97.5 37.2 93.7 21.9 22.9 28.8 38.7 88.1 65.4 10.7 54.3 64.6 56.9 45.0 56.0 97.1 35.0 23.1 50.5 74.4 41.4 66.2 17.9 99.1 65.6 45.1 35.9 36.3 59.2 64.0 51.2 12.1 34.9 24.0 32.1 180.1 24.2 47.2 37.7 140.6 FEZF2 "FEZL, FKSG36, FLJ10142, TOF, Zfp312, ZNF312" ENSG00000153266 "FEZ family zinc finger 2" Q8TBJ5 3 62369681-62374324 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "brain: 179.0" "Cell type enriched" "Detected in some" 4 "Bipolar cells: 51.5" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in all" 6 "cerebral cortex: 179.0;hippocampal formation: 60.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AF22: 1.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 12.2;cerebral cortex: 12.1;hippocampal formation: 21.3" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (2.37e-1)" "unprognostic (1.74e-2)" "unprognostic (1.70e-1)" 0.1 0.0 13.7 0.0 15.6 0.0 0.0 3.8 179.0 0.0 4.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.1 4.6 0.1 0.0 0.0 0.0 18.9 4.1 0.0 0.0 0.0 0.7 0.0 13.4 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 5.8 0.1 0.2 0.0 4.8 2.8 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 15.6 3.8 179.0 60.1 4.6 18.9 4.1 13.4 5.8 4.8 21.1 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 51.5 0.9 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.3;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 24.1;Intestinal goblet cells: 8.9;Kupffer cells: 11.9;Macrophages: 15.4;Prostatic glandular cells: 7.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.7" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.7" "Cell line enhanced" "Detected in some" "HMC-1: 3.9;OE19: 1.8;SK-BR-3: 1.1;THP-1: 1.2;U-937: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA023985 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" 4.9 0.3 0.2 17.8 0.4 20.3 2.3 0.2 0.4 0.2 0.6 0.8 3.3 0.1 0.0 1.3 1.0 1.4 1.0 0.2 0.2 0.3 1.5 7.5 0.1 0.4 0.4 0.0 0.6 0.3 0.1 1.6 0.5 1.1 0.7 0.1 0.7 0.0 0.2 1.1 4.6 1.3 0.2 22.2 1.2 0.0 0.4 0.7 0.4 3.7 0.7 6.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 3.1 2.1 85.0 0.0 5.6 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 249.7 0.0 6.5 0.1 0.0 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.4 0.4 0.5 0.2 0.4 0.8 5.6 0.0 3.2 0.0 0.6 0.1 0.4 0.3 0.0 0.0 0.2 0.3 0.4 0.0 2.7 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.2 0.0 0.1 0.8 24.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 5.1 0.0 0.4 0.0 5.0 0.0 0.0 8.9 2.0 11.9 2.6 0.1 0.0 15.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 7.7 1.1 0.0 2.2 0.0 0.0 0.4 2.4 0.1 0.2 0.0 0.6 0.1 1.3 0.1 0.6 1.5 FFAR3 "FFA3R, GPR41" ENSG00000185897 "Free fatty acid receptor 3" O14843 19 35358460-35360489 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 4.1;lymphoid tissue: 2.5" "Group enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 16.8;Macrophages: 9.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "eosinophil: 2.5;neutrophil: 2.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.8" "Not detected" "Not detected" HPA044681 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044681: AB_2679043" "unprognostic (1.15e-1)" "unprognostic (5.16e-3)" "unprognostic (1.45e-1)" "unprognostic (3.08e-2)" "unprognostic (1.03e-3)" "unprognostic (2.21e-2)" "unprognostic (4.46e-2)" "unprognostic (1.34e-1)" "unprognostic (1.92e-4)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-3)" "unprognostic (2.18e-2)" "unprognostic (3.41e-1)" "unprognostic (3.22e-2)" 4.1 0.1 0.3 2.5 0.5 0.8 2.3 0.3 0.6 0.0 0.5 1.3 0.3 0.0 0.0 0.0 0.3 0.5 0.3 0.5 0.4 0.2 0.2 0.4 0.2 1.2 0.5 0.2 0.4 0.1 0.4 0.4 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.4 1.2 0.5 0.1 0.4 0.2 0.6 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.1 0.3 0.5 0.3 0.6 0.5 0.4 1.2 0.5 0.5 0.4 0.4 1.1 1.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 16.8 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 2.6 1.8 0.3 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.4;pituitary gland: 11.0" "Cell type enriched" "Detected in some" 4 "Intestinal goblet cells: 125.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Uncertain "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" 4.1 0.4 1.2 0.7 1.3 0.1 1.3 0.6 1.2 0.1 0.3 8.3 0.5 0.0 0.0 0.2 1.0 0.5 0.3 1.0 1.8 0.1 0.4 3.6 0.2 0.6 0.8 0.0 0.6 0.1 11.0 0.1 0.5 0.1 11.4 0.2 0.1 0.0 0.3 0.9 0.6 0.2 0.3 0.1 0.5 1.5 2.6 0.3 0.1 0.1 0.1 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 12.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 1.2 1.3 0.6 1.2 1.0 1.8 0.6 0.8 0.5 0.3 2.6 0.7 0.2 0.0 0.5 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.2 0.8 0.4 7.2 0.6 0.0 0.0 0.2 0.0 28.1 0.0 0.8 27.8 0.1 0.0 0.3 20.9 0.0 3.2 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 7.4 0.0 2.0 125.7 0.0 7.2 4.4 16.7 0.6 7.6 1.8 3.7 0.5 0.0 0.0 0.0 0.3 0.9 23.0 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.3 FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;dendritic cells: 29.7;Kupffer cells: 118.2;Langerhans cells: 49.3;Macrophages: 52.0;Microglial cells: 43.1;monocytes: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;Daudi: 11.5;HDLM-2: 11.3;U-698: 9.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" 6.1 3.3 1.0 14.8 1.3 6.0 2.6 1.2 1.3 1.5 2.3 3.4 3.7 1.3 1.5 2.4 2.8 4.1 1.6 1.0 1.6 1.4 2.5 8.0 22.5 3.2 1.7 1.0 1.3 0.3 1.1 2.7 1.9 1.5 2.7 0.1 2.3 1.8 0.6 2.1 11.1 4.7 2.1 39.7 3.8 0.6 2.1 5.5 2.7 0.9 9.8 4.5 1.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 11.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 22.3 2.3 0.1 64.8 0.1 23.2 0.0 0.0 35.0 18.6 0.0 0.0 0.3 0.4 70.5 27.4 0.1 7.5 1.0 1.3 1.2 1.3 1.0 1.6 3.2 1.7 1.9 2.1 2.1 2.0 0.3 6.4 7.4 0.0 53.7 2.0 3.0 1.0 0.6 0.3 0.7 0.6 3.2 2.8 0.5 0.0 0.0 0.3 29.7 0.3 0.0 2.8 11.9 0.5 0.2 1.2 0.0 1.3 0.1 0.9 0.4 1.0 1.5 1.2 7.6 0.0 2.5 0.6 17.7 0.0 0.2 0.1 4.1 118.2 49.3 2.1 1.5 52.0 1.8 43.1 51.8 0.4 2.1 0.5 0.2 1.0 3.9 0.0 14.2 1.6 0.1 0.2 3.2 0.2 0.0 2.3 0.5 0.0 0.1 3.3 2.3 0.4 3.0 0.1 0.4 5.6 FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Endothelial cells: 44.7;Hepatic stellate cells: 55.6;Microglial cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 94.9;TIME: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" 19.8 4.4 4.8 5.6 4.3 0.3 15.0 4.1 4.9 10.4 3.4 5.3 9.2 11.3 2.3 5.7 8.5 11.9 11.5 3.0 2.9 10.1 3.1 20.6 4.2 4.5 11.5 5.3 2.2 3.5 3.2 17.7 4.8 5.3 4.6 0.2 3.7 4.4 6.8 5.4 7.0 11.4 3.2 25.0 4.6 4.3 6.7 2.0 7.5 13.4 3.6 7.7 5.6 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 94.9 0.1 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.4 0.0 81.1 0.0 6.6 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.3 4.1 4.9 3.0 2.9 4.5 11.5 4.8 3.2 6.7 3.0 51.3 0.0 4.6 0.0 0.9 3.1 0.2 0.0 1.2 0.1 1.3 1.9 4.4 1.5 0.6 0.0 0.0 0.3 0.4 0.1 1.9 0.2 7.3 0.4 5.3 44.7 0.0 5.3 3.4 0.2 0.1 11.3 1.1 0.3 0.0 0.0 55.6 1.3 10.5 0.0 8.6 0.2 0.0 2.2 5.9 9.9 11.5 3.3 1.8 25.3 0.0 0.0 1.0 0.5 0.3 4.8 2.5 4.5 0.0 0.3 1.0 7.0 0.0 0.2 0.0 4.9 2.4 0.2 3.6 0.1 1.8 0.5 0.7 2.3 0.5 0.2 FGF8 AIGF ENSG00000107831 "Fibroblast growth factor 8" P55075 10 101770130-101780369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "skeletal muscle: 48.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.1;testis cancer: 3.3" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 17 "RH-30: 37.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.56e-1)" "unprognostic (3.90e-3)" "unprognostic (1.12e-2)" "unprognostic (4.88e-1)" "unprognostic (2.47e-2)" "unprognostic (9.09e-2)" "unprognostic (8.75e-3)" "unprognostic (8.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.95e-2)" "unprognostic (1.17e-2)" "unprognostic (2.35e-9)" "unprognostic (6.17e-3)" "unprognostic (9.01e-2)" "unprognostic (1.97e-1)" 0.5 0.0 0.7 0.0 0.7 0.2 0.2 0.6 1.2 0.1 0.8 0.2 0.3 0.2 0.2 0.9 0.1 0.3 0.3 0.9 1.1 0.1 0.1 0.3 0.3 0.5 0.7 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.1 0.5 0.0 0.1 48.7 0.2 0.0 0.0 0.4 0.6 0.1 1.1 0.7 0.0 0.2 0.0 0.0 0.2 0.0 1.0 0.6 0.1 0.3 1.4 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.6 0.7 0.4 0.6 0.0 0.0 0.5 0.3 0.0 0.0 1.1 1.0 0.4 0.3 0.5 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.1 0.0 1.0 0.3 0.9 0.0 0.4 0.6 2.2 0.2 0.0 0.1 0.6 37.8 0.8 0.0 0.2 0.9 0.9 0.0 0.6 0.5 0.0 0.6 0.1 0.6 0.6 1.1 0.8 0.2 0.2 0.8 1.3 0.8 0.7 0.8 1.9 0.4 0.5 0.3 0.5 0.6 0.4 0.4 0.4 0.4 0.5 0.6 0.5 1.1 0.7 0.9 0.4 0.5 0.3 0.7 0.7 0.6 1.2 0.9 1.1 0.5 0.7 0.6 0.4 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.0;bone marrow: 54.6" "Group enriched" "Detected in many" 6 "dendritic cells: 486.6;NK-cells: 1627.2" "Group enriched" "Detected in many" 9 "glioma: 4.8;head and neck cancer: 13.1;lung cancer: 16.7;melanoma: 16.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 551.3;memory CD8 T-cell: 332.1" "Lineage enriched" "Detected in many" 8 "T-cells: 551.3" "Cell line enhanced" "Detected in some" "SK-MEL-30: 6.9;T-47d: 3.2;WM-115: 1.3" "Secreted to blood" NA NA 346000000 36000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.51e-3)" "unprognostic (8.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (1.35e-2)" "unprognostic (9.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (3.51e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (9.61e-2)" "unprognostic (1.49e-2)" 29.0 1.5 0.9 0.4 1.0 54.6 12.7 0.8 1.5 0.6 0.8 11.8 0.1 0.5 7.2 0.6 0.7 0.9 23.6 1.0 1.1 0.5 1.2 8.5 2.9 0.9 0.8 0.4 0.2 0.3 0.2 0.5 0.9 1.4 0.9 1.1 8.6 0.9 1.1 21.0 2.0 0.3 0.8 14.0 1.7 8.6 0.9 5.3 1.1 3.6 1.0 2.8 1.8 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 6.9 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 3.5 0.8 2.4 551.3 1.3 5.2 0.8 128.6 332.1 0.9 0.4 47.3 314.1 8.4 64.9 1.6 2.1 0.9 371.2 0.9 1.0 0.8 1.5 1.0 1.1 0.9 0.8 0.9 0.8 0.9 0.9 2.6 0.0 5.3 0.0 2.6 9.6 0.0 0.2 0.0 0.0 1.5 1.7 1.5 5.7 1.4 5.5 8.4 0.6 486.6 0.1 0.0 0.7 1.3 0.9 0.1 2.2 0.0 3.6 0.0 0.0 0.0 19.9 0.5 0.3 3.8 60.3 6.1 0.6 0.0 0.0 0.0 0.4 0.0 4.9 12.0 3.0 0.0 2.2 46.2 0.0 5.8 1.4 1627.2 0.0 0.1 0.2 0.0 0.4 17.5 0.0 0.0 1.3 1.3 0.4 0.0 1.8 2.5 0.7 0.1 0.1 7.7 1.0 167.2 0.2 0.1 0.0 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Granulosa cells: 30.9;Hepatocytes: 37.5;Muller glia cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-251 MG: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 7: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" 38.1 56.0 40.8 5.0 43.3 7.6 24.1 40.6 49.5 15.7 29.8 10.2 7.3 9.9 3.4 5.5 36.0 9.3 19.8 39.2 33.5 25.4 52.8 15.1 3.1 49.9 45.8 25.4 71.6 16.1 21.6 3.0 46.5 12.4 4.9 10.5 37.6 2.7 20.6 10.7 13.5 4.0 42.2 9.1 27.2 5.5 47.9 1.4 67.1 9.6 2.2 11.2 8.0 42.1 23.2 31.6 11.3 34.3 11.9 12.3 2.9 40.4 6.2 12.9 8.4 23.1 47.9 2.6 49.3 63.3 58.3 5.8 21.8 14.1 11.8 8.3 21.0 0.3 41.2 61.5 24.0 13.7 5.6 25.7 11.7 22.4 9.5 48.4 12.5 9.3 25.3 8.9 7.9 30.8 16.0 37.7 14.2 39.7 83.8 24.7 16.3 16.7 22.6 3.6 1.2 2.2 38.1 0.8 15.2 13.4 22.5 11.9 26.1 68.8 27.2 35.2 99.8 8.9 12.9 3.8 18.1 15.6 22.8 0.6 0.0 0.0 0.2 1.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 40.8 43.3 40.6 49.5 39.2 33.5 49.9 45.8 46.5 42.2 47.9 42.1 3.8 3.2 4.1 34.0 2.8 6.5 3.7 5.4 2.2 5.4 13.2 6.1 8.5 11.5 6.9 7.3 0.0 1.6 4.1 4.4 0.0 9.6 0.2 6.0 4.2 2.6 1.8 4.8 3.2 10.2 26.6 5.1 6.6 13.5 1.3 30.9 5.3 37.5 3.2 0.0 2.8 11.0 0.0 1.6 2.5 1.2 4.4 3.4 7.2 1.9 1.3 94.0 1.0 5.0 5.4 19.9 2.7 3.4 2.2 11.4 2.9 7.6 7.0 5.6 0.0 3.3 5.1 0.4 4.2 1.2 4.7 1.5 4.2 17.5 3.6 8.8 FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 20 "Early spermatids: 1160.3;Late spermatids: 1540.1" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "ASC diff: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" 35.7 10.3 5.4 4.4 8.5 0.0 16.0 5.8 7.5 27.8 6.2 5.8 2.5 15.0 17.6 9.6 21.5 12.9 5.6 4.9 5.3 6.4 0.4 14.0 1.8 6.3 5.8 11.4 4.6 3.3 1.2 0.6 7.1 4.9 5.0 0.4 2.1 11.1 8.9 5.5 5.1 9.6 5.4 3.5 4.0 65.5 7.2 1.2 8.9 14.6 0.8 6.8 10.3 5.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 8.5 5.8 7.5 4.9 5.3 6.3 5.8 7.1 5.4 7.2 5.5 5.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 0.0 0.1 3.8 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1540.1 52.5 1.1 5.4 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.2 0.0 0.0 0.0 0.0 52.6 1.9 67.4 13.2 4.4 0.0 0.3 0.0 0.6 0.1 0.0 0.2 FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297714-36780055 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 172.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 87.6;Excitatory neurons: 132.2;Granulosa cells: 84.9;Inhibitory neurons: 186.5;Oligodendrocyte precursor cells: 114.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 72.3;HDLM-2: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021827: AB_1848571, HPA024696: AB_1848573" "unprognostic (8.46e-2)" "unprognostic (8.76e-2)" "unprognostic (6.34e-2)" "unprognostic (3.44e-1)" "unprognostic (8.96e-2)" "unprognostic (8.30e-2)" "unprognostic (4.11e-4)" "unprognostic (2.73e-2)" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (2.16e-3)" "unprognostic (4.55e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (4.10e-2)" "unprognostic (3.00e-3)" "unprognostic (1.20e-1)" 3.4 32.1 13.2 2.4 14.3 0.1 6.1 8.7 17.7 5.6 13.9 14.5 1.6 3.0 42.2 9.4 11.2 7.2 172.8 13.8 12.3 23.2 1.4 1.5 1.3 37.9 15.1 6.9 2.1 1.0 10.5 1.3 36.8 27.9 3.4 36.1 11.3 62.8 49.5 6.5 5.5 10.1 11.5 1.3 3.2 4.1 8.5 2.4 3.6 20.5 4.0 14.6 5.2 13.5 15.5 5.4 34.3 8.2 0.2 0.0 2.6 34.1 72.3 6.7 6.5 0.0 24.5 2.8 8.9 16.3 19.2 19.5 11.4 14.8 4.0 80.1 4.0 0.0 1.0 0.1 0.4 0.0 1.1 4.5 7.1 3.6 1.5 36.6 0.2 0.0 0.0 0.2 8.0 0.0 0.1 0.2 7.5 0.0 4.9 0.0 0.0 18.9 32.5 17.0 19.0 44.6 7.4 0.1 4.6 3.0 0.2 0.1 39.6 21.3 1.6 0.9 29.5 31.8 0.0 0.0 23.8 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 14.3 8.7 17.7 13.8 12.3 37.9 15.1 36.8 11.5 8.5 13.5 0.4 0.0 0.0 104.5 0.0 3.2 0.9 8.9 14.8 6.5 2.3 11.4 38.0 0.0 2.7 12.9 87.6 0.1 0.0 0.2 3.9 1.3 1.7 10.2 1.7 0.6 0.0 0.4 132.2 0.9 11.3 7.9 1.1 0.6 0.0 84.9 0.0 0.0 0.2 0.0 186.5 0.2 6.1 0.0 0.6 0.4 0.0 0.3 10.6 11.2 0.0 7.3 0.0 114.1 3.4 3.3 0.1 0.4 0.0 0.6 0.0 7.9 15.3 33.6 0.0 11.2 6.3 2.2 2.8 1.6 0.6 0.4 0.4 29.9 0.3 0.3 FIBIN MGC24932 ENSG00000176971 "Fin bud initiation factor homolog" Q8TAL6 11 26994112-26997087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 33.0;Fibroblasts: 80.8;Granulosa cells: 42.4;Leydig cells: 37.9;Oligodendrocyte precursor cells: 32.2;Peritubular cells: 35.0" "Cancer enhanced" "Detected in all" "glioma: 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 65.2;ASC TERT1: 41.8;fHDF/TERT166: 22.1;HHSteC: 88.2;HSkMC: 89.5;hTCEpi: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040120 Uncertain "Intracellular and membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA040120: AB_10795243" "unprognostic (1.72e-1)" "unprognostic (2.61e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (1.62e-2)" "unprognostic (5.42e-2)" "unprognostic (7.28e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.93e-5)" "prognostic unfavorable (6.72e-4)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.02e-2)" 32.3 4.9 11.0 7.7 10.6 0.0 25.1 11.4 10.8 35.6 6.1 27.8 2.2 26.1 8.0 11.3 35.7 7.9 32.6 10.8 10.7 15.2 2.0 27.2 2.8 10.6 12.7 18.5 3.8 0.3 2.6 12.6 11.7 17.0 2.6 0.6 17.6 61.3 17.1 16.7 12.0 17.1 11.4 14.1 21.1 1.3 11.6 2.1 13.4 14.5 0.9 16.3 58.3 11.7 0.0 0.0 1.0 0.0 65.2 41.8 0.1 2.1 5.7 0.2 0.9 0.0 0.0 0.0 0.0 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 88.2 0.0 0.0 89.5 24.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 10.6 11.4 10.8 10.8 10.7 10.6 12.7 11.7 11.4 11.6 11.7 2.5 0.0 0.0 17.9 0.0 6.6 1.6 33.0 1.8 0.3 1.9 0.9 1.2 11.5 4.0 11.0 0.0 1.2 0.0 0.1 11.7 0.6 0.1 0.0 0.1 1.0 0.0 0.0 0.5 0.0 0.9 80.8 0.0 0.0 0.0 42.4 6.1 0.5 1.8 0.0 0.1 0.0 12.2 0.0 10.3 0.3 37.9 0.8 7.2 0.0 0.0 19.8 0.0 32.2 0.1 0.1 0.0 35.0 0.1 0.2 0.0 4.3 0.9 0.6 0.0 3.7 7.4 0.1 0.3 0.8 5.1 1.9 0.5 3.9 0.0 0.0 FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.8;skeletal muscle: 35.8;tongue: 48.9" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.9;HUVEC TERT2: 1.7;RPTEC TERT1: 1.9;U-266/70: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 38: Heart - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA053564: AB_2682192" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (9.77e-3)" "unprognostic (3.83e-1)" "unprognostic (1.52e-1)" "unprognostic (4.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.17e-3)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-3)" "unprognostic (3.97e-3)" "unprognostic (2.34e-1)" "unprognostic (4.65e-2)" "unprognostic (7.66e-3)" 6.8 1.5 1.5 2.9 1.8 0.2 2.4 0.1 2.5 1.8 0.7 11.7 1.8 8.5 0.9 9.5 4.8 5.7 53.8 4.1 0.5 1.8 3.2 7.6 1.2 0.2 0.5 1.3 1.4 12.4 1.4 5.1 0.3 3.9 3.3 0.4 1.2 3.4 35.8 0.6 2.6 13.2 0.5 0.3 3.2 2.1 0.8 1.1 2.3 48.9 0.9 10.9 1.6 1.5 0.0 1.3 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.1 0.1 0.0 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.9 0.7 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 1.5 1.8 0.1 2.5 4.1 0.5 0.2 0.5 0.3 0.5 0.8 1.5 82.1 128.2 82.6 5.9 0.5 0.6 0.5 2.8 0.0 3.5 0.5 0.8 582.5 0.0 9.1 0.0 0.0 0.8 0.5 0.1 1.9 0.1 54.2 18.2 1.7 45.9 0.0 2.7 9.7 0.4 0.3 60.3 0.0 19.2 1.3 1.7 72.1 0.7 1.3 0.0 12.8 0.1 8.2 1.9 1.2 17.6 2.5 1.8 1.8 5.6 0.0 2.5 1.0 6.0 10.0 0.0 0.0 4.5 0.0 0.8 0.4 0.1 62.4 3.5 92.1 70.2 114.2 7.1 7.9 0.7 0.9 0.8 1.8 11.9 0.1 0.4 FITM2 "C20orf142, dJ881L22.2, FIT2" ENSG00000197296 "Fat storage inducing transmembrane protein 2" Q8N6M3 20 44302840-44311202 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 67.4" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.92e-2)" "unprognostic (7.61e-2)" "unprognostic (2.27e-2)" "unprognostic (2.10e-3)" "unprognostic (1.02e-1)" "unprognostic (3.57e-3)" "unprognostic (1.63e-2)" "unprognostic (3.90e-2)" "unprognostic (8.43e-2)" "unprognostic (5.19e-2)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "prognostic favorable (8.98e-12)" "unprognostic (2.07e-1)" "unprognostic (2.54e-1)" "unprognostic (3.38e-3)" "unprognostic (2.49e-3)" 11.4 11.1 4.8 2.9 5.0 1.2 7.0 5.7 6.3 4.2 5.9 5.2 4.3 4.0 8.7 3.3 3.7 3.2 67.4 4.8 5.9 7.9 6.4 4.1 2.2 6.9 5.9 4.6 7.4 13.6 5.2 1.9 7.4 6.4 6.0 6.7 6.5 4.4 9.2 5.7 3.9 5.3 4.2 2.6 4.6 3.8 5.4 1.7 6.3 16.8 2.6 4.5 3.1 4.7 7.2 10.9 4.5 6.6 31.4 12.8 4.6 11.5 8.4 8.9 4.9 13.5 5.1 4.9 6.5 13.0 14.3 15.8 5.7 7.7 9.6 1.4 2.7 1.6 6.5 22.9 6.6 3.1 4.0 9.7 17.2 6.2 4.7 4.9 6.4 3.1 2.7 14.2 9.1 22.4 1.2 3.4 1.1 10.8 13.9 1.9 8.4 4.9 5.1 6.7 2.7 3.2 24.4 13.5 10.3 2.0 16.5 2.4 7.9 28.2 12.6 16.6 6.8 5.2 14.4 1.3 12.6 4.9 14.4 0.7 1.0 0.6 1.1 1.0 1.2 0.6 1.2 0.9 1.0 0.6 2.0 1.6 0.4 1.4 0.8 0.6 1.2 0.9 4.8 5.0 5.7 6.3 4.8 5.9 6.9 5.9 7.4 4.2 5.4 4.7 2.8 6.4 9.7 1.3 3.6 6.9 3.5 2.8 1.2 6.4 5.0 3.4 153.9 11.5 4.3 5.5 6.2 2.0 1.0 5.1 1.9 5.2 4.6 2.2 5.0 4.4 9.1 0.8 2.3 8.6 3.5 9.4 4.1 2.1 0.0 4.4 8.2 14.1 3.4 6.7 2.1 4.8 0.0 3.8 2.2 1.2 7.8 1.7 7.2 1.0 2.3 6.6 2.1 4.0 0.9 5.7 4.1 7.5 3.1 3.1 5.9 6.2 4.0 5.9 0.0 5.6 6.3 9.1 6.0 2.7 8.1 1.5 2.1 16.3 9.2 2.2 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FKBP11 FKBP19 ENSG00000134285 "FKBP prolyl isomerase 11" Q9NYL4 12 48921518-48926474 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 495.0" "Cell type enriched" "Detected in many" 4 "Plasma cells: 1153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 188.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 332.6;Karpas-707: 315.1;OE19: 527.2" "Low region specificity" "Detected in all" HPA041709 Enhanced Approved Centrosome NA NA 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Centrosome "HPA041709: AB_10794487" "unprognostic (7.45e-3)" "unprognostic (8.62e-2)" "unprognostic (2.40e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (3.46e-2)" "unprognostic (1.75e-1)" "unprognostic (7.64e-2)" "unprognostic (3.49e-3)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.15e-1)" "unprognostic (4.51e-1)" "unprognostic (2.79e-1)" "unprognostic (1.54e-1)" 25.6 17.6 4.0 60.2 4.1 34.5 34.5 3.7 4.9 42.4 5.6 57.2 70.8 17.4 86.4 16.2 19.1 25.4 13.1 3.8 12.0 13.8 59.4 23.9 55.4 5.7 6.3 13.8 495.0 4.7 47.2 15.6 5.2 28.9 53.3 2.1 160.2 32.7 2.4 8.0 55.9 26.2 3.8 76.4 70.6 6.1 9.6 16.4 22.9 0.4 77.4 49.2 17.3 4.8 13.6 24.7 3.0 4.5 116.0 141.3 3.8 123.2 183.3 128.0 154.5 78.3 88.3 192.8 2.2 226.8 1.1 60.6 31.6 60.4 77.0 39.1 7.7 6.6 24.7 0.3 332.6 3.2 3.3 165.0 109.8 99.2 171.4 67.2 75.4 53.1 3.0 315.1 49.9 44.7 26.3 5.1 7.4 527.2 33.9 76.5 3.3 280.7 21.0 2.3 35.0 10.6 36.6 66.5 24.4 4.0 2.0 7.0 49.2 21.0 2.8 2.1 2.3 132.3 122.2 108.1 16.1 3.9 33.0 6.0 1.0 2.8 115.7 1.3 188.3 50.5 80.5 92.7 1.9 25.7 38.8 69.9 4.1 26.7 1.1 39.3 33.4 36.3 4.0 4.1 3.7 4.9 3.8 12.0 5.7 6.3 5.2 3.8 9.6 4.8 22.3 16.0 19.1 5.2 229.8 28.3 56.0 48.6 39.3 5.5 45.0 43.3 2.3 30.0 42.8 9.2 39.6 21.5 130.9 23.1 7.9 23.7 18.4 19.2 117.8 32.3 25.1 20.6 5.3 171.7 80.7 64.1 31.6 31.0 12.7 34.0 40.4 96.6 10.9 1.7 3.7 227.7 16.2 15.1 26.1 17.4 27.7 10.1 272.1 0.0 8.0 1.8 158.6 1.5 1.8 59.8 14.3 13.9 1153.9 111.8 14.1 18.0 43.3 14.6 6.6 10.8 88.7 12.0 9.8 23.0 21.3 42.3 145.3 37.5 49.7 45.0 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 977.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.2;granulocytes: 974.2;monocytes: 1013.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 1749.2;TIME: 1929.6" "CAB004639, HPA051798" Uncertain NA NA 12000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 272.7 185.0 138.4 178.8 177.5 167.0 188.2 88.5 163.2 123.0 112.6 158.6 108.9 165.4 150.1 169.8 131.7 104.5 171.4 166.7 115.8 186.7 98.1 235.2 162.7 92.4 98.9 135.1 114.6 123.0 79.5 218.7 95.6 125.4 188.5 11.8 111.0 119.8 110.3 127.3 117.0 225.1 97.8 185.7 118.3 56.9 120.5 188.1 190.9 150.6 202.2 206.8 126.2 118.9 718.1 299.5 172.9 240.3 654.1 771.3 202.9 423.9 337.1 382.7 354.2 278.4 295.2 272.5 149.3 555.7 656.3 337.7 255.1 1007.2 419.7 68.8 170.5 284.2 113.9 473.3 406.4 390.5 168.0 484.7 332.0 410.3 412.6 513.3 1749.2 401.0 271.0 145.8 443.3 125.8 401.9 453.7 307.1 335.3 276.4 307.0 254.1 351.9 540.0 243.4 248.7 173.8 208.0 479.3 728.8 231.8 177.2 293.0 1929.6 1363.6 201.8 278.1 329.5 76.4 168.1 292.9 248.1 332.3 307.5 316.3 870.8 974.2 112.9 1005.8 104.3 128.1 135.5 133.2 675.2 136.2 140.1 132.6 805.0 160.6 1013.4 312.7 195.0 1153.8 138.4 177.5 88.5 163.2 166.7 115.8 92.4 98.9 95.6 97.8 120.5 118.9 779.1 86.6 77.2 0.0 160.6 263.1 211.2 393.3 152.0 17.6 175.6 156.5 59.7 170.1 179.5 172.9 0.0 281.8 148.3 456.2 238.7 432.4 47.7 98.7 183.8 814.8 330.6 196.4 0.0 337.5 702.0 212.2 160.0 122.5 143.5 95.3 623.6 113.5 746.7 35.3 0.0 245.9 329.6 541.8 436.5 52.2 200.0 428.8 241.9 0.0 527.4 52.2 152.4 0.0 0.0 483.6 977.5 162.9 214.8 221.1 210.8 332.1 123.0 11.7 138.1 87.4 224.7 169.3 141.8 329.4 299.3 231.5 150.1 347.3 318.0 245.7 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FKBP prolyl isomerase 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 892.7;tongue: 925.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 759.3;ASC TERT1: 468.5;HHSteC: 593.0;HSkMC: 718.3;hTCEpi: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm No No 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: AB_2673734" "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 400.1 92.3 18.2 70.1 26.8 26.6 160.4 19.7 32.1 86.4 20.2 110.9 11.3 97.5 63.0 130.6 104.6 78.9 93.7 16.8 20.7 108.8 144.5 92.7 166.7 22.7 23.8 122.1 200.4 227.0 52.9 28.5 23.5 85.0 37.1 25.6 61.0 49.8 892.7 114.0 135.7 81.8 17.0 105.6 129.0 41.4 22.1 229.4 97.2 925.1 80.3 108.9 109.1 26.2 40.0 17.1 73.1 109.7 759.3 468.5 1.2 21.2 1.0 13.6 31.0 29.7 6.9 195.3 19.5 4.1 11.8 0.6 44.1 93.2 32.0 77.7 41.6 84.0 14.1 41.7 593.0 53.3 8.3 718.3 368.6 23.7 220.5 14.8 80.1 38.8 91.3 77.1 144.3 25.3 222.5 99.6 18.9 8.7 12.3 97.7 19.1 95.4 60.2 23.7 27.7 16.8 17.3 19.8 4.2 15.9 108.4 62.2 178.7 19.3 17.3 2.8 29.7 34.9 42.9 243.5 6.6 102.3 7.6 57.6 105.0 70.0 64.4 92.3 78.0 9.7 90.6 68.5 107.5 12.5 133.4 96.7 85.1 45.2 46.8 32.0 37.2 158.5 18.2 26.8 19.7 32.1 16.8 20.7 22.7 23.8 23.5 17.0 22.1 26.2 180.2 12.8 11.3 23.2 42.9 17.6 59.2 20.1 37.0 1.9 32.0 20.8 131.8 74.4 14.2 5.5 0.0 1.2 102.0 14.3 23.5 0.6 9.8 55.7 76.1 57.9 20.9 102.2 25.9 7.9 0.8 97.5 18.8 79.2 38.5 54.7 117.1 225.6 35.1 0.0 2.8 35.5 34.6 384.2 44.8 22.0 160.9 192.2 7.2 66.5 110.3 4.6 44.3 16.6 26.3 2.9 19.3 218.6 66.4 49.9 157.0 27.4 18.2 22.6 144.7 188.1 106.8 14.9 19.1 37.5 21.3 0.4 128.7 2.8 39.5 22.2 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 683.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 64.2;Cholangiocytes: 133.0;Hepatocytes: 265.4;Proximal enterocytes: 108.8;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "Hep G2: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 3.1 5.7 2.0 5.1 2.9 2.0 46.1 3.9 2.8 7.8 0.5 41.3 71.3 2.8 6.9 1.2 3.6 15.8 3.1 2.1 2.4 51.5 683.3 27.1 4.0 4.2 2.9 4.1 48.1 68.3 6.7 2.4 4.8 9.7 46.6 0.9 32.7 4.0 0.8 11.6 73.9 3.5 3.2 4.0 120.1 5.2 3.1 1.1 2.0 1.4 2.5 3.9 1.5 5.6 0.1 1.1 0.6 0.1 2.8 0.8 0.9 0.7 0.5 0.3 0.8 0.7 2.4 0.4 0.8 0.8 0.2 0.4 0.0 0.0 0.0 1.4 0.2 1.6 0.1 41.7 0.9 1.4 9.0 1.3 0.2 0.4 0.0 0.4 0.6 0.2 0.1 0.1 1.5 1.4 0.2 0.7 2.8 5.3 0.8 0.4 0.5 0.4 3.4 0.6 0.5 0.3 0.9 2.8 1.3 1.3 2.1 10.4 1.1 0.0 0.3 0.9 0.0 0.3 0.0 0.3 1.1 0.5 0.3 7.0 12.9 4.1 2.0 5.9 0.3 4.7 0.5 0.6 5.4 8.5 0.3 1.3 1.3 1.2 1.8 2.5 1.6 3.9 2.0 2.9 3.9 2.8 2.1 2.4 4.2 2.9 4.8 3.2 3.1 5.6 2.8 9.6 64.2 11.1 6.4 1.7 3.9 0.9 1.8 2.0 17.5 6.7 1.9 133.0 10.4 14.7 0.0 1.5 1.7 60.8 7.9 7.5 7.7 2.5 1.8 2.7 6.7 4.8 8.2 5.9 1.1 2.9 24.5 6.1 5.7 9.8 5.0 265.4 4.0 3.3 6.4 34.4 4.1 10.0 2.3 4.5 2.8 4.6 28.4 10.3 5.3 0.2 4.1 10.1 17.5 7.0 29.0 1.5 0.4 5.6 108.8 69.2 18.1 1.3 0.0 2.2 1.0 5.9 0.9 1.3 1.6 1.4 2.6 6.6 20.7 6.4 FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.7;Fibroblasts: 52.5;Intestinal goblet cells: 80.2;Leydig cells: 28.0;Peritubular cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.6;CACO-2: 38.6;HHSteC: 11.8;HSkMC: 22.1;OE19: 45.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 71.7" "Secreted to extracellular matrix" NA NA 2600000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (9.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.17e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-1)" "unprognostic (5.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (9.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (2.67e-4)" 122.7 13.6 1.3 31.1 2.3 0.1 64.4 1.5 3.9 100.1 9.0 39.4 49.6 105.8 17.2 19.1 85.8 123.6 149.0 1.0 1.5 24.3 11.0 60.2 28.6 2.4 0.9 125.1 33.1 28.0 21.7 81.2 1.5 58.4 62.1 9.9 49.6 49.2 12.6 25.9 21.2 106.5 2.1 18.2 135.6 6.3 1.5 9.6 71.3 25.6 33.8 45.4 60.0 1.4 0.0 0.1 0.0 0.0 10.6 0.7 0.2 7.1 8.1 0.0 1.1 38.6 0.0 0.0 0.8 7.7 0.0 0.3 0.0 0.6 0.5 0.0 0.0 0.0 0.9 0.0 11.8 0.0 0.0 22.1 0.1 0.0 0.4 5.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.3 0.0 45.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 1.0 0.3 2.0 0.0 0.3 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.3 1.5 3.9 1.0 1.5 2.4 0.9 1.5 2.1 1.5 1.4 9.3 0.0 6.3 0.0 0.0 6.9 5.0 1.5 6.2 0.2 10.3 26.7 1.6 2.8 2.1 7.3 0.0 1.1 0.4 2.9 0.0 1.9 0.1 1.1 12.1 8.3 6.1 0.0 0.1 0.7 0.7 52.5 12.8 1.6 0.0 0.5 19.2 0.1 1.2 0.0 0.0 80.2 0.0 0.3 9.3 0.4 28.0 0.6 12.4 7.5 0.6 11.9 0.0 0.0 0.0 1.5 2.2 28.6 0.0 11.7 0.7 0.2 0.7 1.0 6.6 1.3 15.5 0.0 0.3 0.6 4.3 3.1 1.2 2.0 8.6 1.6 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 124.2;liver: 126.9" "Cell type enhanced" "Detected in many" "Early spermatids: 255.2;Hepatocytes: 130.9;Late spermatids: 557.6;Pancreatic endocrine cells: 89.2" "Cancer enhanced" "Detected in all" "glioma: 39.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 35.3;ASC diff: 34.7;HUVEC TERT2: 43.3;SH-SY5Y: 33.2;TIME: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Aggresome, Cytosol" "HPA051804: AB_2681617, HPA063581: AB_2685048" "unprognostic (2.57e-1)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.46e-3)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (8.28e-3)" "unprognostic (4.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (5.74e-3)" "unprognostic (2.40e-3)" "prognostic unfavorable (6.11e-4)" 34.5 124.2 55.4 2.9 54.6 0.0 26.2 59.8 69.0 7.5 40.3 5.9 1.1 4.2 2.7 24.9 3.8 12.2 11.7 58.9 56.0 11.4 126.9 4.6 1.1 64.6 57.5 38.3 11.9 36.5 11.2 2.5 63.6 11.8 1.8 10.4 9.0 3.2 4.1 4.9 3.4 5.4 56.2 5.4 5.6 27.3 59.2 0.4 5.9 4.0 2.8 6.0 8.0 56.1 0.0 0.3 19.9 35.3 34.7 21.2 0.3 8.1 16.3 5.8 5.0 1.6 0.6 0.0 0.9 25.9 7.5 0.0 13.3 4.9 5.0 0.0 2.2 1.7 0.1 18.7 12.9 0.0 0.2 18.2 2.3 10.0 2.0 26.0 43.3 0.0 1.9 0.0 21.3 0.0 0.0 0.1 12.4 0.0 0.7 0.0 0.0 0.0 3.4 0.0 0.3 33.2 0.2 0.0 0.3 2.6 0.1 0.0 39.7 5.4 2.4 2.1 6.3 0.0 0.0 0.0 29.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 54.6 59.8 69.0 58.9 56.0 64.6 57.5 63.6 56.2 59.2 56.1 14.8 0.0 0.5 5.2 0.8 3.4 3.2 0.4 5.7 9.1 8.3 12.8 2.4 14.3 0.2 0.0 4.2 0.2 0.4 0.0 3.9 72.9 255.2 1.6 18.8 10.9 0.0 2.7 20.1 48.3 0.2 17.3 6.1 2.0 5.7 5.9 10.0 130.9 0.5 0.0 18.7 0.5 0.0 3.2 5.3 557.6 15.5 1.0 3.6 5.6 1.0 23.7 0.0 10.6 2.1 89.2 0.0 11.7 0.7 11.9 0.0 0.4 0.2 12.9 0.0 34.4 15.6 5.0 8.4 1.4 2.4 0.0 1.5 1.0 0.1 1.7 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589552-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 74.7;stomach 1: 28.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 113.8;Basal squamous epithelial cells: 76.8;Breast glandular cells: 87.9;Enteroendocrine cells: 84.6;Prostatic glandular cells: 89.8;Respiratory ciliated cells: 66.7;Urothelial cells: 154.5" "Group enriched" "Detected in many" 5 "breast cancer: 80.0;prostate cancer: 127.0" "Region enriched" "Detected in single" 5 "midbrain: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 48.9;MCF7: 105.3;PC-3: 69.5;RT4: 96.7;SK-BR-3: 97.0;T-47d: 135.9" "Region enhanced" "Detected in some" "midbrain: 1.1" "Region enriched" "Detected in single" 6 "midbrain: 5.4" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "CAB011595: AB_2104842, HPA050505: AB_2681148" "unprognostic (1.61e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (3.01e-1)" "unprognostic (1.54e-2)" "unprognostic (6.30e-2)" "unprognostic (0.00e+0)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.69e-2)" "prognostic favorable (1.00e-4)" 0.2 0.1 0.0 1.6 0.0 0.0 22.3 0.0 0.0 1.5 0.0 12.4 8.4 0.1 0.6 11.9 2.4 2.3 0.0 0.0 0.3 0.1 26.9 7.5 0.0 0.1 3.5 0.0 0.5 0.0 0.7 0.0 0.2 74.7 10.4 0.0 19.3 0.3 0.0 1.3 4.8 0.2 0.2 0.0 28.0 0.4 0.7 0.0 0.0 0.0 2.3 20.5 4.4 0.0 4.9 4.4 0.0 2.8 0.0 0.0 0.5 0.0 0.4 0.0 0.0 21.3 2.7 0.0 1.4 0.0 0.1 23.4 13.2 3.3 0.1 0.0 23.4 0.0 4.1 48.9 0.0 0.0 0.2 0.0 0.7 0.0 0.4 1.9 0.0 0.4 0.9 0.0 0.0 105.3 0.1 0.3 0.0 32.0 69.5 0.0 1.1 0.4 9.9 96.7 11.8 0.0 4.8 97.0 0.0 0.0 135.9 0.4 0.0 0.9 0.1 0.4 3.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 3.5 0.2 0.2 0.7 0.0 0.3 28.9 43.5 0.0 0.1 1.0 113.8 47.8 76.8 0.0 87.9 34.8 1.3 30.0 52.3 3.7 0.0 0.0 0.5 27.5 0.0 1.5 0.4 2.7 0.2 1.2 84.6 0.0 0.0 2.4 0.0 1.0 35.7 4.4 2.5 0.0 1.1 31.7 0.0 0.0 0.0 34.9 42.7 0.9 0.3 0.9 0.0 0.7 3.6 0.0 1.0 0.0 0.0 0.0 0.0 4.3 27.2 0.0 1.2 89.8 4.9 0.0 66.7 0.0 0.0 0.0 2.3 0.9 1.2 62.9 0.1 0.0 1.4 0.1 27.9 154.5 FOXN4 ENSG00000139445 "Forkhead box N4" Q96NZ1 12 109277978-109309284 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 11.4" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Endometrial ciliated cells: 2.6;Ionocytes: 2.0;Respiratory ciliated cells: 1.2;Spermatocytes: 2.8;Spermatogonia: 3.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SCLC-21H: 3.5;SH-SY5Y: 3.6;U-266/70: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA050018 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Mitochondria" Cytosol "HPA050018: AB_2680992" "unprognostic (1.09e-3)" "unprognostic (9.63e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (2.52e-2)" "unprognostic (1.18e-1)" "unprognostic (3.27e-2)" "unprognostic (7.93e-3)" "unprognostic (2.30e-1)" "unprognostic (1.02e-3)" "unprognostic (1.05e-1)" "unprognostic (1.43e-1)" "unprognostic (6.00e-2)" 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.2 1.8 0.5 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.3 0.8 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 11.4 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.1 2.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FOXO1 "FKH1, FKHR, FOXO1A" ENSG00000150907 "Forkhead box O1" Q12778 13 40555667-40666641 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Autophagy, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.0" "Cell type enhanced" "Detected in many" "Astrocytes: 177.3;Endometrial stromal cells: 161.0;Granulosa cells: 177.9;Oligodendrocytes: 131.5;Skeletal myocytes: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 40.4;Daudi: 45.3;HSkMC: 53.6;U-698: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001252, CAB022326" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022326: , HPA001252: AB_1078906" "unprognostic (4.72e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-2)" "unprognostic (4.35e-1)" "unprognostic (2.42e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.74e-4)" "unprognostic (6.35e-2)" "unprognostic (1.60e-1)" "unprognostic (8.65e-3)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.33e-5)" "unprognostic (1.93e-1)" "unprognostic (5.44e-1)" "unprognostic (9.09e-2)" "unprognostic (9.63e-2)" 43.2 9.7 11.2 13.1 16.1 13.8 27.6 10.0 10.9 19.1 16.7 13.8 5.0 39.1 6.5 13.0 25.7 14.5 13.9 9.1 11.8 11.8 38.5 16.8 23.8 14.1 12.7 65.6 16.5 5.3 7.6 11.2 12.7 10.1 9.6 3.9 9.8 10.1 91.0 18.0 10.9 27.0 10.5 15.7 9.5 8.9 11.3 11.6 19.0 22.2 24.0 13.4 17.4 14.3 0.7 1.7 12.4 0.3 40.4 7.9 11.8 1.8 2.5 0.5 0.3 3.7 3.0 45.3 8.1 1.2 1.9 10.7 9.8 5.3 0.7 20.9 10.1 0.0 1.4 10.1 19.1 0.4 1.2 53.6 35.5 0.2 6.7 2.5 31.7 3.3 0.9 14.0 3.1 1.6 0.1 0.6 18.0 6.2 3.1 32.4 14.3 3.6 22.9 5.8 2.6 0.6 1.6 8.5 1.8 14.1 1.5 1.1 18.6 0.3 2.3 0.1 1.1 7.9 3.3 57.8 1.2 2.1 5.7 0.9 0.6 0.5 1.3 0.8 1.8 3.7 3.6 2.2 0.4 5.8 5.5 4.3 2.5 1.4 1.4 0.0 5.1 1.0 11.2 16.1 10.0 10.9 9.1 11.8 14.1 12.7 12.7 10.5 11.3 14.3 57.9 0.0 4.4 177.3 29.3 29.3 19.1 13.0 27.9 3.7 12.9 17.3 11.5 10.0 9.9 9.2 12.5 0.5 22.9 27.5 0.0 11.1 7.2 55.4 161.0 50.2 52.2 3.2 7.4 18.0 3.8 40.8 18.8 118.8 1.3 177.9 84.3 47.9 6.5 5.0 23.0 21.0 8.2 14.6 26.9 4.0 18.6 18.6 12.4 117.1 18.4 5.5 8.2 47.3 131.5 19.5 16.3 13.2 32.9 10.1 7.7 8.8 9.2 9.8 6.6 131.7 31.3 6.4 14.6 25.3 26.7 0.8 40.3 64.0 12.5 13.0 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 119.6;Kupffer cells: 215.3;Macrophages: 178.5;monocytes: 89.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Group enriched" "Detected in some" 5 "LHCN-M2: 17.2;U-87 MG: 67.1" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 69.6 10.0 3.8 166.0 4.4 195.3 5.3 4.1 8.7 8.2 5.7 4.6 3.1 3.7 0.5 8.9 15.4 28.6 7.5 3.6 8.1 4.5 21.4 50.8 12.7 15.2 8.2 2.4 11.2 5.1 3.5 45.1 11.9 3.1 3.3 2.6 4.1 2.3 1.8 1.3 5.2 42.9 8.6 129.2 5.4 2.2 9.9 8.4 3.1 22.8 10.3 66.9 2.7 18.2 0.5 0.8 0.3 0.4 1.0 2.1 0.5 0.2 0.0 0.5 2.0 0.3 0.7 1.2 0.6 0.0 3.9 0.4 0.0 0.0 0.1 0.1 0.0 0.7 0.9 1.0 6.0 0.3 0.5 4.8 0.2 1.8 1.8 9.2 0.0 0.3 0.1 0.6 17.2 0.9 0.1 0.3 0.4 0.3 0.7 0.3 0.7 0.0 1.5 0.5 0.2 0.3 0.6 0.1 0.5 0.2 1.0 1.1 1.0 2.0 0.4 0.1 3.5 0.2 0.0 0.5 67.1 1.7 0.1 317.1 759.9 204.9 1.6 319.7 1.5 0.7 1.0 0.7 174.1 1.0 1.0 1.2 4199.5 0.4 201.8 8.1 1.3 420.3 3.8 4.4 4.1 8.7 3.6 8.1 15.2 8.2 11.9 8.6 9.9 18.2 0.1 16.0 25.7 0.0 1.8 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.2 0.0 15.5 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.8 0.0 0.1 6.3 0.0 2.5 0.2 0.0 1.6 4.7 0.5 0.1 26.5 0.0 2.5 2.1 119.6 0.0 0.1 0.0 0.0 215.3 4.7 2.0 0.3 178.5 0.0 3.7 89.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.4 8.8 0.3 6.6 0.6 0.8 0.6 0.8 0.2 0.0 3.0 2.5 0.0 0.0 0.1 FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Group enriched" "Detected in some" 15 "Hofbauer cells: 56.5;Kupffer cells: 97.4;Langerhans cells: 223.6;Macrophages: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Group enriched" "Detected in some" 5 "HEL: 10.0;hTERT-RPE1: 2.7" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" 10.6 12.1 0.6 23.9 1.1 0.4 5.3 0.5 2.4 5.5 2.2 12.6 11.2 3.7 1.5 5.7 2.0 18.8 3.8 0.6 0.7 3.2 21.3 28.2 13.9 3.1 1.0 1.7 2.3 2.2 0.9 5.6 2.8 2.5 18.2 0.3 2.4 2.9 0.9 2.7 14.4 8.9 1.2 16.3 7.1 2.7 6.0 8.1 2.2 2.0 11.0 17.4 1.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.6 1.1 0.5 2.4 0.6 0.7 3.1 1.0 2.8 1.2 6.0 3.9 0.5 0.0 1.7 0.3 2.7 5.6 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.0 2.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 1.5 56.5 0.0 0.2 0.0 0.0 97.4 223.6 0.2 0.3 66.6 7.2 1.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.1 0.0 0.0 1.5 0.1 0.0 0.3 0.5 0.0 0.1 0.4 4.5 0.8 0.6 0.0 0.0 0.1 FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.6;Cardiomyocytes: 73.7;Cone photoreceptor cells: 79.2;Early spermatids: 121.9;Horizontal cells: 101.0;Late spermatids: 122.8;Sertoli cells: 72.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Cell line enhanced" "Detected in many" "HEL: 24.0;OE19: 49.2;RPMI-8226: 79.6;SCLC-21H: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" 9.4 7.3 6.6 2.0 5.5 5.4 6.7 4.3 6.8 3.0 12.0 5.5 2.9 2.7 15.7 2.5 2.2 2.5 85.0 6.3 7.7 14.9 0.7 4.0 1.3 10.1 8.5 1.4 1.6 20.6 4.2 14.8 7.3 2.8 6.6 21.6 2.9 7.8 81.2 2.1 6.7 3.5 7.6 7.2 2.8 9.9 9.9 1.1 7.1 74.7 0.5 4.6 2.6 5.4 0.0 4.3 3.8 0.3 0.7 0.2 0.3 4.1 0.3 0.1 0.0 0.5 5.2 0.9 4.7 1.9 0.9 0.2 0.2 0.0 0.0 0.2 0.2 24.0 4.8 2.8 0.2 0.0 0.3 1.0 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.1 4.9 0.7 0.0 0.1 0.4 49.2 7.2 0.1 3.0 79.6 6.2 10.1 28.4 13.8 1.4 0.3 0.9 0.6 1.7 0.8 4.4 0.2 0.6 0.1 2.9 0.4 0.3 0.0 0.9 7.6 2.8 0.0 2.0 0.0 0.2 3.4 0.4 0.3 0.1 0.0 0.2 0.4 0.0 0.0 2.5 0.3 1.5 0.4 0.0 6.0 6.6 5.5 4.3 6.8 6.3 7.7 10.1 8.5 7.3 7.6 9.9 5.4 38.4 22.4 1.1 6.2 0.4 1.0 1.0 0.6 0.6 108.6 2.6 1.9 73.7 15.7 1.8 1.8 79.2 0.4 0.2 28.9 17.6 2.8 121.9 2.8 1.4 25.8 1.2 0.8 37.9 2.0 1.2 8.8 2.0 3.9 0.0 0.4 4.2 0.3 0.8 101.0 70.0 38.3 0.0 4.4 0.6 122.8 2.1 8.3 0.0 27.2 4.2 3.9 1.0 10.1 16.0 2.3 10.0 4.9 0.0 1.6 43.6 12.4 3.2 7.0 72.3 66.6 50.7 4.1 1.4 0.2 1.3 0.1 0.9 29.8 2.4 2.3 FRMD4A "bA295P9.4, FLJ10210, FRMD4, KIAA1294" ENSG00000151474 "FERM domain containing 4A" Q9P2Q2 10 13643706-14462142 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 60.8" "Group enriched" "Detected in many" 7 "Excitatory neurons: 1527.6;Inhibitory neurons: 1622.8;Microglial cells: 1329.4;Oligodendrocyte precursor cells: 442.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.3" "Lineage enriched" "Detected in single" 5 "B-cells: 2.3" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 134.0;HUVEC TERT2: 105.8;TIME: 191.6;WM-115: 163.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038449 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA038449: AB_10669539" "unprognostic (6.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.51e-3)" "unprognostic (5.68e-2)" "unprognostic (1.55e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.21e-3)" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (9.20e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" "unprognostic (8.16e-2)" "unprognostic (1.84e-1)" 60.8 5.2 38.9 11.7 28.1 5.4 18.7 0.0 29.2 8.6 0.0 13.1 5.7 5.7 4.0 9.4 8.8 9.6 16.7 24.1 8.5 19.5 12.2 14.2 9.1 15.6 10.9 6.8 15.5 2.4 8.7 22.5 6.2 10.3 6.4 14.1 13.6 10.2 8.1 32.0 7.4 6.5 10.0 32.8 7.9 8.8 14.4 15.6 8.1 7.3 8.4 10.4 8.9 18.9 7.0 7.1 90.1 0.5 12.3 22.0 16.9 40.8 36.5 35.2 48.7 12.1 4.2 0.1 28.3 21.5 48.6 13.5 0.3 3.3 30.7 0.3 9.9 1.4 0.9 0.2 11.0 0.5 1.1 12.8 3.2 134.0 16.4 98.9 105.8 3.1 13.6 0.4 64.7 8.5 4.6 0.8 24.6 0.3 9.6 0.4 30.8 0.2 16.6 5.8 4.3 15.9 0.2 32.7 64.4 16.1 18.5 3.3 191.6 48.8 17.4 47.6 49.3 0.3 0.4 0.3 41.7 1.0 163.4 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.3 0.1 0.0 2.3 0.3 0.0 0.3 0.2 0.0 0.4 0.4 0.0 38.9 28.1 0.0 29.2 24.1 8.5 15.6 10.9 6.2 10.0 14.4 18.9 48.6 32.1 2.6 168.1 1.7 35.1 13.1 3.0 9.1 54.2 17.1 14.4 11.4 45.8 4.1 33.1 18.8 69.6 0.4 1.1 11.7 15.8 42.5 13.1 5.5 44.0 4.8 81.7 1527.6 4.0 42.1 14.9 4.6 26.9 15.2 58.1 44.3 6.2 35.9 80.8 1622.8 3.4 6.1 95.6 19.9 98.8 2.1 25.5 16.0 1329.4 2.7 46.0 0.0 442.3 61.0 1.8 1.4 1.9 0.9 8.0 0.3 2.7 2.5 12.9 13.1 41.2 45.5 1.3 2.1 20.6 32.7 28.7 3.0 5.3 5.4 4.3 FRMPD2 "MGC35285, PDZD5C, PDZK5C" ENSG00000170324 "FERM and PDZ domain containing 2" Q68DX3 10 48153088-48274696 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 5.2;retina: 24.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 50.0;Cone photoreceptor cells: 287.7;Early spermatids: 97.7;Endometrial ciliated cells: 70.6;Late spermatids: 118.5;Respiratory ciliated cells: 62.9;Rod photoreceptor cells: 90.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HBEC3-KT: 1.0;SCLC-21H: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (1.53e-1)" "unprognostic (3.08e-1)" "unprognostic (7.88e-4)" "unprognostic (7.59e-2)" "unprognostic (2.37e-1)" "unprognostic (2.06e-1)" "unprognostic (6.54e-3)" "unprognostic (1.85e-1)" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-12)" "unprognostic (3.48e-2)" "unprognostic (5.43e-2)" "unprognostic (1.54e-1)" "unprognostic (7.43e-5)" 0.0 0.0 2.4 0.0 2.0 0.0 0.4 2.7 1.3 0.2 5.2 0.0 0.0 0.1 0.1 0.0 3.0 0.0 0.9 2.1 2.7 0.1 0.0 0.2 0.0 4.7 6.7 0.0 0.0 0.0 0.1 0.0 4.1 0.3 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.0 2.7 1.3 2.1 2.7 4.7 6.7 4.1 4.0 3.5 3.4 0.0 0.0 0.5 36.6 0.0 0.1 0.4 1.6 0.0 50.0 1.1 0.4 5.0 0.0 4.6 3.7 287.7 0.2 0.0 0.1 0.0 0.1 97.7 70.6 0.5 0.3 3.0 0.0 2.0 0.0 0.3 0.8 0.0 1.6 0.0 0.0 0.0 0.2 0.1 3.3 0.9 0.6 6.1 0.0 0.0 118.5 0.3 0.2 0.0 0.0 0.0 5.2 0.0 0.5 0.3 0.2 0.1 0.4 0.0 0.4 4.2 0.5 62.9 90.8 0.0 0.2 0.6 2.1 1.0 0.0 0.3 0.0 0.1 0.1 0.7 0.4 FSIP1 FLJ35989 ENSG00000150667 "Fibrous sheath interacting protein 1" Q8NA03 15 39588357-39782841 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 10.9;testis: 7.2" "Cell type enhanced" "Detected in many" "Early spermatids: 67.1;Excitatory neurons: 28.2;Inhibitory neurons: 21.5;Late spermatids: 48.3;Spermatocytes: 35.3" "Cancer enriched" "Detected in some" 8 "breast cancer: 6.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 4.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA041002 Uncertain Uncertain Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA041002: AB_10796565" "unprognostic (1.55e-2)" "unprognostic (1.49e-1)" "unprognostic (9.12e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.43e-3)" "unprognostic (5.17e-3)" "unprognostic (5.37e-2)" "unprognostic (9.22e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-2)" "unprognostic (2.49e-1)" "unprognostic (1.22e-2)" "unprognostic (1.14e-1)" "unprognostic (3.81e-2)" "unprognostic (2.01e-1)" "unprognostic (1.81e-1)" 0.2 0.2 1.6 0.2 1.8 0.6 0.9 0.0 1.6 0.2 1.7 7.3 0.1 0.3 0.3 0.1 1.2 0.2 0.2 1.2 1.8 0.8 0.1 0.2 0.1 1.1 1.3 0.1 0.1 0.8 1.4 0.3 0.9 0.2 10.9 0.9 0.1 0.2 0.2 0.9 0.1 0.3 0.3 0.2 0.5 7.2 2.0 1.4 0.4 0.1 0.1 0.3 0.1 0.4 0.4 1.3 3.4 0.5 0.6 1.1 0.0 4.1 0.8 0.6 1.2 1.0 0.3 0.2 0.3 1.2 1.7 0.8 0.5 0.7 1.0 1.4 0.3 2.5 0.9 0.0 0.3 0.5 2.7 0.7 2.8 1.5 0.6 0.8 0.7 1.4 0.1 0.3 1.0 0.1 0.3 0.2 0.4 0.2 0.6 0.3 0.7 0.1 1.3 1.5 0.8 2.5 0.8 0.1 0.1 0.3 1.1 0.3 0.6 1.6 0.9 0.9 0.4 0.7 1.6 0.2 3.3 0.9 0.8 0.4 0.3 0.4 0.7 0.2 0.5 0.1 0.3 0.4 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 1.6 1.8 0.0 1.6 1.2 1.8 1.1 1.3 0.9 0.3 2.0 0.4 0.7 0.0 0.5 8.1 1.1 0.6 0.6 3.4 0.0 1.1 14.5 7.9 0.8 2.8 2.9 1.8 12.5 0.9 1.4 17.5 1.9 1.0 67.1 10.0 2.1 1.0 0.0 0.0 28.2 0.4 0.1 1.5 0.5 0.6 15.8 0.4 0.4 0.0 0.1 0.0 21.5 3.5 0.0 0.0 0.3 48.3 1.2 0.6 0.0 7.5 0.1 1.0 3.1 3.0 3.2 0.1 6.6 0.7 0.4 0.7 0.0 3.2 12.6 6.1 0.0 1.2 1.5 35.3 8.3 0.2 0.0 5.6 3.3 0.7 2.9 0.3 FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868588-90883564 "Enzymes, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 305.6;salivary gland: 220.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 117.5;Hepatocytes: 131.8;Pancreatic endocrine cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009499, HPA067869" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA 130000 "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095, HPA067869: " "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" 54.5 24.4 12.8 36.4 10.5 73.8 42.4 10.6 14.5 26.4 11.7 32.8 27.6 32.3 9.8 33.7 30.4 19.4 58.5 14.9 9.0 56.8 305.6 63.2 13.0 12.5 10.8 22.4 108.6 27.3 45.9 40.6 11.3 60.1 12.1 12.9 220.5 17.7 61.3 62.7 35.5 14.3 10.4 51.4 34.0 8.6 15.6 11.8 56.1 25.3 11.2 30.2 33.3 9.3 50.8 31.2 6.8 29.8 49.4 32.1 77.5 64.4 48.1 26.3 18.1 45.4 54.3 1.9 148.8 47.5 46.1 91.5 14.0 32.5 5.4 148.0 35.2 90.9 52.8 57.7 26.2 13.0 141.2 35.6 35.3 29.5 13.2 62.4 84.7 14.6 70.5 8.5 17.8 32.3 5.0 29.2 21.5 44.2 9.3 7.9 26.6 10.9 35.2 39.1 13.1 9.2 54.5 28.5 42.5 31.9 10.7 31.4 125.9 29.4 60.1 43.7 95.5 15.2 93.4 3.4 55.8 40.1 60.7 2.0 0.9 1.5 0.7 0.1 0.2 0.4 0.2 0.3 0.6 0.1 0.0 0.1 0.7 0.4 0.0 0.3 0.0 1.1 12.8 10.5 10.6 14.5 14.9 9.0 12.5 10.8 11.3 10.4 15.6 9.3 44.1 3.2 27.4 4.2 7.3 19.4 10.0 10.4 2.8 12.8 12.0 9.0 16.3 21.5 8.5 22.0 25.0 20.9 26.9 49.5 0.0 47.1 0.5 15.2 9.7 29.4 37.8 26.5 7.9 117.5 16.5 11.4 21.9 32.3 15.8 7.0 23.9 131.8 24.8 8.4 7.5 31.7 10.2 35.3 42.1 1.4 11.1 33.6 16.0 5.6 14.0 13.6 24.7 2.0 4.4 108.3 26.4 10.9 7.2 24.3 28.7 7.8 2.0 28.0 26.3 10.5 18.6 2.8 3.6 8.5 23.0 84.3 19.6 4.7 17.9 16.4 FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.1;Hepatocytes: 651.7;Leydig cells: 430.3;Muller glia cells: 343.4;Skeletal myocytes: 188.7;Smooth muscle cells: 205.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Cell line enhanced" "Detected in some" "ASC diff: 46.7;ASC TERT1: 13.5;HSkMC: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" 141.4 26.1 496.5 9.6 528.9 2.2 125.1 506.1 637.3 291.9 616.5 168.3 14.3 173.3 62.1 70.7 187.3 56.3 557.7 487.5 503.4 28.6 558.7 85.8 6.6 568.0 515.0 144.7 19.2 3.8 39.8 29.3 494.8 116.0 25.6 35.9 37.2 73.5 1381.3 48.3 67.2 104.5 511.1 20.8 72.6 12.1 560.2 8.2 38.0 838.7 6.7 80.0 194.9 498.6 1.1 0.0 0.0 0.2 46.7 13.5 1.3 5.7 0.1 0.0 0.0 0.0 0.3 3.8 1.5 0.0 0.1 1.0 1.1 0.7 0.0 3.4 1.3 0.7 0.0 1.9 5.2 0.3 0.4 19.3 0.0 0.1 0.5 0.5 0.2 0.1 1.0 3.7 0.1 0.0 0.1 0.8 0.2 2.8 0.6 0.0 0.2 1.1 0.0 0.0 0.3 0.2 0.7 0.2 1.8 0.3 0.2 6.1 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.4 0.9 0.6 7.7 1.6 0.3 0.0 1.3 0.7 0.8 11.0 3.6 1.5 0.3 6.9 0.7 0.9 0.5 2.1 0.8 0.6 6.9 0.6 496.5 528.9 506.1 637.3 487.5 503.4 568.0 515.0 494.8 511.1 560.2 498.6 46.1 0.0 0.0 44.4 15.8 29.4 3.7 2.7 8.0 1.8 4.4 18.0 0.3 11.5 0.8 25.8 4.2 1.2 9.5 42.2 0.0 0.1 1.9 2.2 47.4 13.3 0.0 8.4 3.7 4.9 1.6 225.1 2.0 1.2 0.0 0.1 36.0 651.7 4.4 0.0 0.4 0.8 2.0 14.4 49.0 12.0 430.3 5.3 53.4 2.8 1.0 343.4 1.0 1.5 0.5 1.1 5.3 128.2 2.5 3.3 0.4 0.2 12.6 8.6 118.3 188.7 205.7 10.7 21.7 3.0 27.3 2.9 18.8 0.1 0.7 2.5 FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115879-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1800.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1870.8;Distal enterocytes: 5605.4;Intestinal goblet cells: 2165.8;Paneth cells: 3324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 896.3;hTCEpi: 1603.2;OE19: 3112.0;RT4: 860.2;SK-BR-3: 830.8;WM-115: 589.7" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" 5.1 1.1 7.3 59.5 7.4 1.3 225.2 7.1 7.9 168.0 7.5 1466.2 102.7 13.2 15.2 685.3 104.3 100.5 5.8 7.1 6.5 12.0 2.0 150.2 0.8 8.0 7.3 1.8 64.3 0.1 24.7 84.9 6.8 512.1 1800.0 45.4 569.1 33.3 2.1 568.3 308.9 35.7 6.7 0.6 572.4 0.6 7.0 18.7 1.5 0.1 163.3 295.6 395.8 7.4 166.3 0.0 0.0 0.4 0.6 0.4 150.5 0.0 0.0 0.0 0.0 6.0 235.3 0.3 0.5 0.0 1.3 896.3 0.1 339.5 0.0 0.1 0.3 1.0 7.7 0.6 0.1 0.1 0.6 0.0 1603.2 0.0 0.7 0.1 0.1 0.1 0.1 1.1 0.0 304.5 0.8 2.2 0.8 3112.0 1.4 0.8 0.4 1.2 0.0 860.2 190.2 2.1 1.0 830.8 61.8 2.3 155.9 0.2 0.0 0.3 0.6 0.9 0.7 0.1 0.4 0.7 1.0 0.3 589.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 7.3 7.4 7.1 7.9 7.1 6.5 8.0 7.3 6.8 6.7 7.0 7.4 3.1 762.8 262.6 0.3 11.1 576.9 792.9 1870.8 340.4 2.9 557.5 515.7 1.3 201.6 1026.4 134.3 0.0 883.5 8.3 5605.4 1.9 35.6 0.4 180.1 29.5 19.7 974.3 2.7 0.1 708.4 138.1 20.3 356.8 194.1 22.3 0.0 0.0 0.9 81.4 1.7 0.0 2165.8 587.9 0.0 68.3 0.0 0.0 15.6 412.6 0.0 1.6 422.1 0.0 0.0 0.6 556.5 3324.0 0.0 6.5 1041.7 1693.0 0.5 1627.1 13.3 0.0 0.5 66.5 0.2 0.2 541.1 865.5 1512.1 17.9 0.0 1499.3 1509.9 FYB1 "ADAP, FYB, FYB-120/130, SLAP-130" ENSG00000082074 "FYN binding protein 1" O15117 5 39105252-39274528 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.0;lymphoid tissue: 112.8" "Cell type enhanced" "Detected in many" "dendritic cells: 142.9;Extravillous trophoblasts: 88.7;Hofbauer cells: 157.0;Macrophages: 104.2;T-cells: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1670.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HEL: 61.5;JURKAT: 211.9;MOLT-4: 212.9;REH: 61.3;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025336, HPA026796, HPA067427" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 6200000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB025336: , HPA026796: AB_10964126, HPA067427: " "unprognostic (5.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (6.26e-2)" "unprognostic (4.08e-1)" "unprognostic (3.29e-2)" "unprognostic (2.60e-1)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (5.63e-2)" "unprognostic (5.35e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.40e-1)" "unprognostic (4.14e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-1)" 10.2 5.8 5.7 82.5 5.5 53.0 5.1 6.3 9.3 6.6 7.4 10.0 9.1 3.8 10.5 5.7 3.6 16.8 2.4 5.4 7.9 5.0 13.6 17.6 85.8 16.7 19.1 2.7 1.8 2.1 1.5 17.9 15.8 4.2 11.0 0.5 7.4 3.0 1.2 2.0 15.0 11.6 9.3 73.0 12.2 3.3 13.3 112.8 2.6 2.7 63.0 17.1 1.8 13.9 0.2 4.2 0.0 0.0 0.5 0.0 21.1 0.1 1.2 0.3 0.4 0.4 0.3 0.3 0.0 0.0 8.0 16.4 0.0 0.3 0.1 0.3 0.0 61.5 0.0 0.1 0.0 23.3 18.6 0.3 0.4 0.0 0.4 0.1 0.0 211.9 0.0 0.0 0.0 0.0 212.9 13.5 0.2 0.1 0.1 61.3 0.0 0.3 1.0 3.5 0.1 0.0 0.1 0.5 6.5 1.4 0.0 5.2 0.0 0.0 0.2 0.2 0.2 0.4 0.0 4.5 0.0 81.4 0.2 151.3 359.0 354.6 76.3 406.5 52.9 1.8 216.7 134.5 127.6 1.3 271.7 169.8 1670.8 89.9 483.9 30.8 231.5 400.1 5.7 5.5 6.3 9.3 5.4 7.9 16.7 19.1 15.8 9.3 13.3 13.9 4.4 16.0 24.7 0.0 6.2 0.0 0.0 0.0 0.0 0.0 3.2 7.6 0.0 0.0 5.6 14.7 0.0 28.8 142.9 0.0 9.8 0.4 0.0 0.7 1.1 4.3 0.0 0.0 0.0 0.0 88.7 3.8 0.0 1.0 15.2 0.1 0.0 0.0 157.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 35.9 3.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 40.2 119.3 0.1 0.0 0.0 FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 382.6;dendritic cells: 291.6;NK-cells: 228.6;Oligodendrocyte precursor cells: 342.8;Proximal tubular cells: 212.2;T-cells: 275.8" "Cancer enhanced" "Detected in all" "glioma: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 16 "NK-cells: 69.0;T-cells: 174.8" "Cell line enhanced" "Detected in many" "U-2197: 538.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Enhanced "Plasma membrane,Cytosol" NA NA 820000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "CAB005034: AB_562117, CAB018387: AB_627642, HPA023887: AB_1849226, HPA063770: AB_2685119" "unprognostic (8.62e-3)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "prognostic favorable (1.84e-4)" "unprognostic (4.60e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "prognostic favorable (4.78e-4)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-4)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (6.62e-3)" "unprognostic (2.40e-1)" 76.6 10.8 117.1 52.4 106.4 32.3 46.8 83.8 104.3 45.5 33.3 32.9 16.4 45.6 33.8 16.0 51.4 32.1 40.5 102.1 121.5 23.9 20.4 63.5 108.9 136.3 104.9 28.8 8.5 18.7 22.9 29.7 107.0 17.6 15.6 26.9 12.9 12.5 12.3 41.5 47.1 38.0 109.9 71.9 29.3 16.5 105.7 86.1 45.7 18.3 67.6 48.4 33.4 109.8 10.4 1.5 178.6 30.2 133.4 81.4 3.2 29.1 90.8 24.2 42.9 1.3 1.6 21.0 18.3 56.1 21.0 1.3 25.8 39.9 46.8 0.7 66.5 57.0 13.6 2.7 78.7 19.5 19.0 78.8 59.1 90.5 76.8 62.9 99.5 99.6 4.9 140.3 86.8 1.5 92.7 17.9 26.0 3.3 18.0 29.1 24.0 1.4 0.0 9.1 124.6 50.7 5.7 2.4 124.7 39.6 1.3 57.0 63.9 72.3 13.5 538.7 18.5 20.0 19.7 32.5 136.0 44.3 128.9 1.1 6.4 0.2 137.0 5.6 174.8 4.8 83.9 152.7 7.4 6.4 27.9 72.3 3.0 69.0 4.2 4.3 79.2 51.5 117.1 106.4 83.8 104.3 102.1 121.5 136.3 104.9 107.0 109.9 105.7 109.8 87.8 0.0 8.3 382.6 26.0 17.1 2.5 0.6 1.8 57.2 2.9 6.9 11.3 14.3 2.1 7.3 0.0 2.7 291.6 1.2 17.6 9.3 3.7 5.6 51.7 70.3 13.2 20.9 118.7 1.0 2.4 61.9 17.9 4.9 52.0 20.9 76.4 60.3 3.0 47.1 127.6 3.8 2.0 35.8 96.1 3.2 26.4 42.7 37.4 88.1 64.5 89.1 228.6 342.8 162.3 9.7 0.1 7.2 96.2 3.9 17.7 212.2 4.4 8.3 13.1 48.8 32.9 3.9 8.6 0.7 13.4 52.0 275.8 71.1 2.9 1.1 FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 120.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.0;Collecting duct cells: 36.8;Endothelial cells: 51.2;Hepatic stellate cells: 99.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 63.6;Hep G2: 85.2;HSkMC: 46.0;HUVEC TERT2: 93.6;TIME: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" 120.1 9.5 6.7 5.8 6.2 0.3 55.6 5.1 7.3 12.5 7.8 14.9 2.8 12.2 7.6 6.5 16.3 11.5 27.4 5.6 5.9 27.1 14.6 32.9 6.2 6.5 6.3 12.9 9.5 6.4 8.7 11.7 7.0 12.5 6.3 1.1 12.2 30.2 31.5 5.9 8.8 13.4 5.6 14.1 14.1 5.1 8.5 3.9 18.1 40.6 4.6 10.5 9.5 5.9 1.3 1.1 2.7 5.2 63.6 16.5 3.7 8.4 7.6 3.2 3.3 7.1 0.9 0.0 1.8 2.6 4.4 2.8 3.1 1.3 2.5 0.2 2.1 2.8 2.3 85.2 18.9 0.0 0.1 46.0 0.5 2.8 0.5 7.5 93.6 0.1 3.9 0.4 2.2 2.2 0.0 0.0 3.9 7.5 18.8 0.1 4.8 0.2 9.0 13.7 0.6 0.8 3.5 1.0 1.4 5.6 12.0 0.0 46.3 7.8 5.1 9.2 1.7 0.4 1.3 0.0 1.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 5.1 7.3 5.6 5.9 6.5 6.3 7.0 5.6 8.5 5.9 83.0 0.0 1.3 9.8 0.5 1.5 0.5 1.3 2.2 0.7 5.5 3.2 8.3 7.2 2.0 36.8 10.4 0.2 0.5 1.0 3.9 0.5 0.7 0.4 2.7 51.2 0.0 2.7 8.1 1.6 0.2 17.7 4.1 0.5 0.0 9.1 99.6 14.1 0.2 0.0 3.4 1.3 0.0 6.7 1.8 2.2 9.3 0.6 0.0 10.3 0.0 0.2 2.1 3.0 0.7 1.0 0.1 6.8 0.3 1.4 0.7 9.4 2.1 0.2 32.9 14.4 26.6 0.3 3.2 1.3 0.6 0.3 0.4 16.6 1.1 0.2 FZD5 "C2orf31, DKFZP434E2135, HFZ5" ENSG00000163251 "Frizzled class receptor 5" Q13467 2 207762598-207769906 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 23.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 117.4;Hepatocytes: 59.8;Intestinal goblet cells: 50.1;Muller glia cells: 50.7;Undifferentiated cells: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 104.7;CACO-2: 26.2;Hep G2: 36.5;NTERA-2: 31.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052361 Approved NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052361: AB_2681799" "unprognostic (4.97e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" "unprognostic (1.53e-1)" "unprognostic (2.82e-1)" "unprognostic (4.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-3)" "unprognostic (1.29e-1)" "unprognostic (8.00e-2)" "unprognostic (7.72e-2)" "unprognostic (2.51e-1)" "unprognostic (9.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.15e-3)" 6.0 5.0 1.8 2.5 3.5 4.2 2.4 1.8 3.6 3.0 3.5 18.3 18.6 2.3 0.6 3.3 1.2 1.4 1.6 1.7 3.6 5.1 23.5 6.7 1.1 3.2 4.9 4.2 10.4 1.0 4.7 4.4 2.5 6.3 14.7 10.9 3.1 2.7 2.6 1.0 15.3 2.6 1.8 2.0 11.2 0.4 2.7 1.5 8.7 2.0 1.4 1.7 2.3 6.2 3.3 5.8 0.3 3.1 2.6 0.1 104.7 0.5 0.7 0.8 0.7 26.2 6.0 0.6 7.0 0.3 2.0 4.8 9.0 3.9 0.7 0.4 6.9 7.6 2.8 36.5 2.0 1.5 2.0 0.2 3.7 1.2 3.0 2.0 1.0 1.1 15.5 1.2 0.7 2.3 0.8 1.9 31.0 14.2 2.0 1.9 3.3 1.4 7.3 11.4 5.0 0.7 1.4 0.6 1.5 14.1 1.7 1.5 0.4 1.6 3.0 3.2 2.5 1.7 4.1 1.3 2.1 1.7 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.5 1.8 3.6 1.7 3.6 3.2 4.9 2.5 1.8 2.7 6.2 6.5 32.1 32.6 4.6 2.0 5.1 5.4 5.4 6.2 2.2 8.7 3.7 7.8 25.8 4.8 1.8 33.3 18.9 1.6 117.4 0.0 14.9 0.7 9.0 2.2 4.1 12.6 15.1 0.5 24.7 6.0 3.2 17.3 18.8 0.0 16.8 2.9 59.8 10.5 6.7 0.9 50.1 6.1 8.4 9.8 0.1 1.8 3.3 1.8 1.0 0.7 50.7 0.0 0.0 6.0 18.2 38.6 0.4 0.5 12.5 43.2 12.2 3.4 7.0 0.0 8.1 4.5 1.5 2.1 4.0 4.1 4.0 1.4 8.1 57.6 5.9 G0S2 ENSG00000123689 "G0/G1 switch 2" P27469 1 209675412-209676390 "Metabolic proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 796.7;bone marrow: 1345.4" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 5188.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 44.5" "Immune cell enriched" "Detected in some" 60 "neutrophil: 549.5" "Lineage enriched" "Detected in many" 213 "granulocytes: 549.5" "Cell line enhanced" "Detected in many" "ASC diff: 460.8;HBEC3-KT: 726.2;PC-3: 180.6;RPMI-8226: 242.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "unprognostic (1.67e-3)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.82e-1)" "unprognostic (2.21e-1)" "unprognostic (5.04e-3)" "unprognostic (3.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.32e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (7.57e-3)" "unprognostic (1.53e-2)" "unprognostic (4.78e-2)" "unprognostic (2.64e-1)" 796.7 194.3 7.0 95.7 7.5 1345.4 519.5 7.4 44.5 9.2 8.2 20.9 7.6 34.3 11.7 8.6 26.8 15.7 175.9 8.8 6.8 262.6 664.6 318.4 7.6 7.4 8.6 47.5 31.0 0.8 9.5 13.8 9.1 38.3 4.0 0.6 59.8 14.8 651.4 24.3 31.7 10.9 7.9 49.3 63.8 30.1 7.8 5.9 23.7 303.4 5.4 136.2 17.3 9.7 0.0 4.3 0.0 0.0 460.8 16.1 0.3 0.7 1.4 1.9 1.8 19.3 14.8 0.0 4.1 3.4 2.5 0.0 0.0 726.2 4.4 0.7 1.2 0.0 1.5 0.6 37.5 0.2 0.1 47.8 1.6 32.4 0.0 15.8 0.0 0.0 0.2 0.0 0.2 0.0 0.2 15.7 1.3 0.0 180.6 0.0 0.0 242.8 1.7 0.3 0.9 1.4 16.3 0.0 4.0 0.0 0.2 56.7 73.6 0.0 4.9 0.2 0.1 0.0 1.1 0.1 13.1 0.1 0.0 0.0 1.0 9.1 0.0 1.1 0.4 0.1 2.5 0.1 0.3 0.3 0.0 0.0 549.5 0.0 0.2 0.0 0.0 0.4 7.0 7.5 7.4 44.5 8.8 6.8 7.4 8.6 9.1 7.9 7.8 9.7 52.3 9.6 59.5 5.9 16.1 232.4 654.8 760.7 124.1 0.6 295.2 43.3 359.1 14.3 111.6 11.0 0.0 1.8 5.0 16.6 299.3 52.3 25.3 42.7 12.0 264.5 29.3 6.9 0.9 148.2 3.6 730.2 11.7 112.0 39.1 34.7 12.1 179.4 174.2 0.0 3.1 32.6 22.4 78.2 5188.4 12.3 114.6 1060.3 327.3 2.8 30.7 23.1 1.0 11.1 0.9 736.5 42.9 71.5 10.3 416.7 41.1 304.9 42.3 0.3 32.9 56.4 60.1 52.1 1.1 35.2 161.4 4.2 33.3 7.5 52.5 513.7 GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.5;epididymis: 8.8" "Group enriched" "Detected in many" 5 "Astrocytes: 425.4;Excitatory neurons: 156.2;Inhibitory neurons: 111.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "U-2 OS: 4.2;U-87 MG: 2.1;WM-115: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Uncertain "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (2.45e-4)" "unprognostic (6.87e-3)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.09e-1)" "unprognostic (6.90e-3)" "unprognostic (8.83e-2)" "unprognostic (2.22e-5)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 1.2 0.3 20.2 0.4 29.9 0.2 1.3 2.6 31.5 0.5 0.0 3.0 0.9 0.4 8.8 0.7 0.0 0.5 0.2 29.4 16.0 6.3 0.4 0.1 0.3 0.3 1.9 0.7 0.1 0.0 0.5 0.4 0.0 0.1 2.1 2.4 0.2 0.7 0.1 0.2 6.0 0.2 1.3 1.2 0.5 0.5 13.8 0.4 0.1 0.1 0.4 0.2 0.7 8.8 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 4.2 0.2 0.0 0.2 0.6 0.0 2.1 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 29.9 2.6 31.5 29.4 16.0 0.3 1.9 0.0 1.3 13.8 8.8 4.9 0.0 0.0 425.4 0.0 0.1 0.0 0.0 1.2 15.3 0.2 0.0 0.6 0.0 0.0 40.5 4.2 0.0 0.0 23.1 3.9 0.0 9.1 1.2 31.7 1.0 31.8 0.0 156.2 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 111.6 3.4 0.0 0.0 0.0 17.1 0.6 0.1 1.8 16.9 0.0 0.2 0.0 13.0 5.5 0.0 4.7 0.0 0.0 0.0 38.1 0.1 0.0 1.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.0 2.7 0.0 GABRE ENSG00000102287 "Gamma-aminobutyric acid type A receptor subunit epsilon" P78334 X 151953124-151974680 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "brain: 52.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.7;Syncytiotrophoblasts: 61.4;Urothelial cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.4;EFO-21: 11.6;HeLa: 6.1;SiHa: 5.6" "Region enriched" "Detected in many" 4 "hypothalamus: 18.4" "Region enhanced" "Detected in many" "hypothalamus: 32.3" HPA045918 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA045918: AB_10961281" "unprognostic (1.33e-2)" "unprognostic (6.75e-2)" "unprognostic (3.50e-3)" "unprognostic (1.39e-3)" "unprognostic (2.43e-1)" "unprognostic (7.52e-2)" "unprognostic (5.06e-3)" "unprognostic (1.27e-1)" "unprognostic (3.58e-2)" "unprognostic (1.55e-1)" "unprognostic (6.44e-2)" "unprognostic (6.73e-2)" "prognostic unfavorable (4.05e-11)" "unprognostic (1.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (5.28e-2)" 9.7 0.4 6.3 0.3 4.5 0.0 4.4 0.0 9.7 1.7 0.9 0.4 0.7 0.6 1.8 1.0 0.7 0.5 9.5 0.8 52.3 1.1 0.1 0.6 0.2 5.1 38.0 0.8 0.8 0.9 2.2 3.3 33.0 1.8 0.3 0.1 0.8 3.4 0.3 3.2 0.4 0.3 0.2 0.2 0.3 0.1 14.0 0.1 1.0 0.0 0.2 0.6 2.3 0.2 0.2 0.0 0.1 0.0 3.4 0.0 0.0 0.5 0.0 0.8 0.4 1.9 0.6 0.0 11.6 2.5 0.0 1.9 0.0 0.6 0.5 0.0 0.4 1.3 6.1 0.7 0.2 0.0 0.1 0.8 0.5 0.9 0.2 1.1 0.4 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.7 0.0 0.8 0.0 0.0 1.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 4.5 0.0 9.7 0.8 52.3 5.1 38.0 33.0 0.2 14.0 0.2 7.7 16.0 9.3 0.7 0.7 17.2 22.9 18.6 30.7 0.0 6.8 4.6 7.3 11.5 25.2 1.8 0.0 25.0 0.5 10.0 0.0 4.1 2.0 7.6 12.8 9.0 1.8 0.0 0.0 0.4 3.5 9.2 0.0 29.2 0.0 0.1 4.2 0.9 3.0 0.0 0.0 2.3 4.1 0.6 4.6 3.5 1.5 0.3 1.8 2.8 0.7 0.6 1.0 0.0 0.0 6.1 7.4 2.2 0.0 19.2 21.6 0.2 5.6 0.3 0.0 19.6 5.7 1.2 2.1 22.5 10.9 61.4 1.3 0.1 3.6 42.2 GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 68.4;Kupffer cells: 72.1;Late spermatids: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 84.3;HMC-1: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" NA NA 53000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" 15.0 17.2 20.0 14.9 23.3 23.2 13.3 22.1 26.1 12.0 20.8 15.1 33.3 11.1 12.2 6.6 20.7 18.4 13.5 18.5 21.6 21.3 12.1 23.9 11.7 23.0 22.6 15.8 10.8 9.4 9.8 16.8 23.9 14.3 17.3 18.4 8.1 9.3 8.0 9.1 34.4 9.6 22.3 15.4 16.4 24.0 20.8 9.7 24.5 12.9 7.9 13.6 7.5 30.6 0.0 19.5 7.2 0.0 23.8 21.3 0.0 9.1 17.9 8.3 9.9 10.8 84.3 5.3 26.4 8.7 0.0 1.3 0.0 1.0 10.2 2.7 0.6 29.8 0.7 0.0 19.5 0.1 78.4 20.7 6.6 5.6 0.0 3.4 22.6 0.0 10.0 3.9 14.4 1.9 0.0 4.5 6.5 35.4 2.2 0.0 0.5 0.3 13.4 7.8 6.7 15.6 24.6 4.0 0.2 17.2 20.4 20.5 19.7 0.0 12.9 5.6 0.2 4.2 8.0 0.0 2.3 6.8 19.2 25.3 15.2 34.2 11.1 16.6 24.0 2.5 8.3 10.8 8.9 1.2 6.0 7.0 11.9 16.3 13.4 1.6 5.3 11.7 20.0 23.3 22.1 26.1 18.5 21.6 23.0 22.6 23.9 22.3 20.8 30.6 11.3 25.6 19.0 26.8 8.0 8.4 5.6 9.4 3.4 10.1 9.1 5.2 9.2 10.0 8.9 14.7 12.5 6.2 27.6 15.3 3.9 9.8 51.6 17.3 10.9 11.4 6.1 13.7 17.8 11.4 12.7 15.2 7.7 5.8 68.4 15.9 18.2 6.1 26.6 3.3 21.2 10.2 4.1 72.1 11.8 77.9 16.1 25.0 10.6 8.4 26.7 7.3 40.2 33.2 42.6 14.1 20.0 10.1 9.3 6.1 15.9 6.7 22.1 10.4 0.0 9.8 10.6 14.9 10.0 3.5 11.5 6.6 21.2 12.9 16.7 7.9 GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807670-98850081 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 74.7;intestine: 55.8;stomach 1: 54.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.2;Intestinal goblet cells: 142.4;Undifferentiated cells: 42.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 128.4;U-2197: 160.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA048292, HPA071076" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA048292: AB_2680343, HPA071076: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favorable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" 5.0 2.0 1.2 7.7 1.3 2.2 3.4 6.5 1.8 8.7 4.3 55.3 34.2 3.7 74.7 19.6 7.5 10.5 1.2 1.1 1.4 4.8 0.4 11.7 3.2 2.6 1.4 0.4 13.6 6.3 3.4 2.6 2.7 4.6 55.8 0.6 25.5 4.3 1.3 3.4 27.1 14.0 1.1 2.2 54.8 4.6 1.5 3.3 14.7 0.6 6.1 11.9 4.6 1.6 5.4 4.1 3.4 13.5 10.0 7.8 0.0 1.4 2.1 2.0 4.6 0.8 21.6 0.0 5.0 0.9 12.2 38.0 2.9 1.3 1.6 26.2 1.7 2.4 0.2 0.0 0.5 1.6 0.5 3.8 0.9 6.4 0.0 2.7 2.3 19.3 30.2 0.0 0.6 13.9 2.6 4.7 16.7 128.4 5.6 6.5 0.3 0.1 2.3 7.7 12.4 1.1 0.5 30.6 3.0 7.7 4.5 4.5 4.3 0.0 0.3 160.9 0.0 2.1 4.8 2.3 37.1 0.0 0.9 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.4 0.2 0.0 0.1 0.6 0.3 0.0 0.6 0.0 0.1 0.0 0.1 1.2 1.3 6.5 1.8 1.1 1.4 2.6 1.4 2.7 1.1 1.5 1.6 1.3 3.2 25.7 2.0 2.3 2.4 1.3 8.3 1.2 2.4 0.4 0.1 1.0 18.6 16.9 11.0 16.7 1.0 2.6 101.2 0.0 11.2 1.8 4.8 1.6 1.6 19.9 1.3 7.4 25.4 1.7 12.5 32.1 8.7 2.5 2.4 0.0 0.0 2.3 0.0 5.7 142.4 2.0 0.3 3.9 1.4 2.1 3.9 0.0 3.7 0.2 0.8 3.1 3.5 7.0 32.0 36.5 7.5 1.7 7.4 21.9 2.7 16.9 0.2 0.0 0.7 1.5 5.9 10.5 9.9 1.3 1.1 4.5 5.1 42.5 11.1 GALNT2 GalNAc-T2 ENSG00000143641 "Polypeptide N-acetylgalactosaminyltransferase 2" Q10471 1 230057990-230282122 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 429.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011222 Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 13000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA011222: AB_1849446" "unprognostic (1.26e-1)" "prognostic unfavorable (1.22e-6)" "unprognostic (1.15e-2)" "unprognostic (1.35e-2)" "unprognostic (8.70e-3)" "unprognostic (7.77e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.48e-8)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (1.70e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.79e-13)" "unprognostic (3.79e-3)" "unprognostic (1.49e-1)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" 32.9 49.6 17.0 34.8 19.9 13.9 21.9 15.2 16.7 24.7 22.0 28.9 19.5 27.1 6.9 21.0 22.4 21.2 27.4 15.8 18.6 18.5 100.1 27.1 14.0 23.0 19.5 39.2 68.1 9.9 13.6 27.6 18.3 21.4 12.4 19.8 22.1 14.3 67.4 14.7 23.6 25.0 15.3 17.4 33.1 19.7 25.1 42.8 19.0 27.4 11.2 33.4 19.5 15.5 79.5 103.7 59.9 71.4 112.4 95.3 122.8 146.3 90.0 58.4 55.6 45.2 146.5 20.0 106.2 77.7 135.9 150.7 39.9 123.0 48.6 200.1 52.0 60.7 217.2 50.9 60.9 23.4 114.8 136.9 59.8 78.0 30.9 127.3 69.2 110.1 77.0 29.6 65.6 21.8 122.3 23.9 82.1 52.8 97.7 134.3 85.5 61.7 57.4 92.9 18.9 70.1 148.4 7.9 91.0 31.7 46.5 43.5 165.3 56.7 107.9 129.5 118.0 97.9 60.3 44.4 146.1 46.3 429.7 1.5 10.7 3.6 4.4 9.3 3.2 3.4 2.6 4.5 7.8 5.8 2.5 5.0 3.2 2.8 10.2 13.2 3.3 7.7 17.0 19.9 15.2 16.7 15.8 18.6 23.0 19.5 18.3 15.3 25.1 15.5 18.6 16.0 21.3 71.5 32.1 15.3 20.0 52.8 20.5 30.8 13.8 10.7 13.6 18.6 30.1 23.9 33.3 7.3 21.7 24.1 5.9 49.7 47.2 18.7 15.4 17.9 16.8 27.6 67.3 133.0 123.4 36.1 21.4 24.5 13.3 20.5 19.6 98.8 24.9 28.6 82.0 18.9 4.1 42.4 9.7 24.6 35.8 28.9 24.9 106.8 44.0 10.9 18.6 72.9 44.6 88.5 21.6 29.3 109.0 23.5 17.9 19.2 23.5 73.5 13.1 33.1 25.4 3.4 14.0 16.6 8.0 16.6 21.2 32.8 17.6 29.9 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 95.2;Intestinal goblet cells: 47.0;Late spermatids: 150.2" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 23.4;U-266/84: 7.6" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 0.4 0.6 3.2 1.8 3.3 0.0 0.6 2.7 5.1 0.5 2.0 14.0 5.7 0.3 0.1 0.1 0.6 0.0 2.5 3.2 2.8 0.4 0.2 0.3 0.2 3.4 3.2 0.7 0.2 0.0 2.8 0.1 3.3 0.4 31.3 0.2 0.4 0.3 0.1 0.2 12.6 0.8 2.9 0.5 0.5 13.5 3.3 0.0 0.2 0.0 0.0 0.4 0.3 4.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 23.4 0.0 0.0 0.0 0.1 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 3.2 3.3 2.7 5.1 3.2 2.8 3.4 3.2 3.3 2.9 3.3 4.1 0.1 6.4 0.5 1.3 0.5 0.0 0.0 0.1 0.6 2.1 0.1 2.3 4.5 0.0 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 95.2 0.5 0.1 0.5 6.6 0.0 1.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 47.0 0.0 0.0 0.0 150.2 1.5 0.1 0.0 3.7 0.2 0.5 0.0 15.1 7.4 0.2 0.6 2.6 0.0 0.1 1.0 1.0 0.0 0.6 6.6 0.7 0.1 12.3 8.3 0.0 0.0 0.0 0.8 0.3 2.2 0.0 GAS1 ENSG00000180447 "Growth arrest specific 1" P54826 9 86944362-86947506 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 105.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 127.1;Muller glia cells: 90.3;Skeletal myocytes: 213.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 30.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.2;ASC diff: 29.3;BJ hTERT+: 59.8;HSkMC: 41.1;RH-30: 91.1" "Low region specificity" "Detected in all" "CAB024164, HPA036085, HPA066902" Approved Approved "Nuclear speckles" NA NA 27000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "CAB024164: AB_2107950, HPA036085: AB_2674932, HPA066902: AB_2685746" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.97e-2)" "unprognostic (6.15e-2)" "unprognostic (2.84e-2)" "unprognostic (6.46e-2)" "unprognostic (6.91e-2)" "unprognostic (3.32e-1)" "unprognostic (1.28e-3)" "unprognostic (2.25e-3)" "unprognostic (4.30e-2)" "prognostic unfavorable (1.96e-5)" "prognostic unfavorable (8.26e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.13e-5)" "unprognostic (3.59e-2)" 81.5 6.4 3.6 16.6 4.4 0.2 38.3 3.5 4.4 27.1 16.1 27.6 2.2 105.4 15.2 5.8 60.7 10.5 27.1 3.2 2.7 12.5 2.2 7.8 6.8 3.8 3.8 45.1 11.2 1.9 8.4 22.1 3.6 22.6 2.3 3.3 13.1 9.6 12.2 22.2 9.3 43.4 3.4 3.6 16.3 1.8 3.8 7.1 15.9 9.3 3.1 22.5 27.1 6.8 0.0 0.0 7.5 44.2 29.3 10.9 0.8 8.8 59.8 2.9 2.6 0.0 0.1 0.0 0.5 15.8 0.3 0.6 0.0 0.3 1.2 5.2 17.8 0.0 25.0 0.0 14.9 0.1 0.7 41.1 6.3 1.0 5.3 0.0 0.0 0.9 0.0 0.0 12.6 0.0 0.0 0.4 9.5 0.3 0.1 9.6 91.1 0.0 0.4 0.0 1.0 4.0 12.9 0.0 14.1 4.8 0.1 0.2 0.1 13.0 3.6 0.9 3.0 0.0 0.0 0.0 0.4 0.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.4 3.5 4.4 3.2 2.7 3.8 3.8 3.6 3.4 3.8 6.8 15.8 0.0 0.6 2.0 0.4 25.9 7.5 10.9 10.2 8.3 3.9 28.3 5.5 0.0 3.1 14.7 10.4 21.5 7.8 0.1 9.8 0.5 0.1 2.4 36.6 5.6 0.0 0.4 1.2 0.4 3.7 127.1 1.1 2.0 0.0 2.1 22.9 0.3 5.8 5.0 2.6 0.3 0.0 1.0 15.4 0.9 32.3 2.2 17.8 1.9 0.2 90.3 7.2 8.5 4.4 0.2 0.0 12.4 2.1 4.5 0.0 2.6 0.7 3.2 39.5 213.7 15.4 0.3 1.3 1.0 12.5 4.5 2.1 0.8 0.2 0.4 GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 348.3;Sertoli cells: 322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.7" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.7" "Cell line enhanced" "Detected in many" "BJ: 347.0;BJ hTERT+: 494.0;HSkMC: 281.3;RPMI-8226: 493.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" NA NA 8900000 3600000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Centriolar satellite" "HPA008275: AB_1849497, HPA056080: AB_2683032" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-3)" "unprognostic (1.37e-1)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (4.81e-3)" "unprognostic (1.97e-1)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "prognostic unfavorable (8.93e-6)" 124.2 32.5 26.7 18.8 28.7 3.6 77.4 33.9 32.0 244.4 59.3 67.8 48.7 171.7 13.8 63.2 161.3 58.9 169.1 24.1 34.6 72.7 37.1 97.3 22.5 37.4 36.1 118.0 49.9 58.5 58.4 51.6 38.5 100.9 25.2 6.3 84.4 63.8 99.2 101.4 47.8 57.9 30.8 29.4 70.0 60.1 34.1 39.6 101.2 67.5 10.6 127.0 172.0 25.2 151.3 6.6 4.4 3.8 169.5 94.0 18.4 347.0 494.0 141.3 168.4 9.6 71.0 1.4 11.4 157.2 24.9 139.1 2.4 77.7 35.6 0.2 20.1 1.1 11.1 1.0 120.8 1.0 2.1 281.3 44.9 39.1 39.0 243.2 5.3 2.3 2.6 79.9 231.9 7.4 0.8 1.5 9.5 24.0 9.9 4.5 0.1 493.5 51.9 1.9 23.5 21.3 38.3 1.3 0.4 23.8 45.9 119.4 81.7 36.9 45.0 4.4 100.5 0.1 8.0 1.5 41.9 3.6 5.8 0.0 1.4 0.0 0.0 1.1 0.0 0.1 0.2 0.0 11.3 0.1 0.0 0.0 0.0 0.1 0.3 70.7 0.0 1.4 26.7 28.7 33.9 32.0 24.1 34.6 37.4 36.1 38.5 30.8 34.1 25.2 133.2 198.7 25.9 23.2 20.8 84.4 94.7 18.5 70.0 38.0 17.9 114.3 86.8 50.1 23.4 31.3 0.0 1.8 59.1 92.4 27.4 45.7 5.1 35.2 33.1 71.9 10.3 5.3 26.2 6.7 1.9 152.7 19.9 32.3 8.2 154.7 159.9 21.6 101.6 348.3 31.9 69.5 8.2 22.3 100.4 8.9 92.2 48.6 122.7 41.2 9.8 32.7 0.0 3.0 7.5 24.1 58.6 59.5 147.4 30.5 84.1 0.6 15.5 12.5 322.1 22.9 121.1 5.3 17.6 27.6 71.9 2.9 4.7 214.8 151.4 31.1 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GBE1 ENSG00000114480 "1,4-alpha-glucan branching enzyme 1" Q04446 3 81489703-81761645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 149.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 287.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038073, HPA038074, HPA038075" Enhanced Approved Cytosol NA NA 6500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA038073: AB_10673040, HPA038074: AB_10672403, HPA038075: AB_10674545" "unprognostic (3.10e-1)" "unprognostic (1.02e-3)" "unprognostic (6.76e-2)" "unprognostic (1.05e-2)" "unprognostic (3.48e-2)" "unprognostic (1.89e-1)" "unprognostic (9.01e-3)" "unprognostic (1.17e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (2.19e-2)" "unprognostic (5.68e-2)" "unprognostic (1.46e-1)" "unprognostic (5.36e-2)" "unprognostic (4.42e-1)" "unprognostic (2.83e-3)" "unprognostic (3.78e-3)" 73.9 53.8 4.5 14.9 5.7 19.7 38.6 7.1 8.2 14.2 14.2 11.8 13.2 17.3 14.2 18.1 13.8 13.0 55.6 6.2 8.2 41.4 108.6 17.2 8.6 10.7 18.7 14.2 14.2 19.1 10.4 25.6 10.3 13.2 13.8 22.0 15.5 14.9 149.1 14.4 11.5 21.8 7.0 12.0 11.1 7.9 7.4 11.4 19.6 56.6 13.2 19.2 13.9 7.4 61.3 36.2 11.9 168.7 287.6 216.8 21.5 99.1 140.1 58.1 97.6 7.1 15.6 67.9 42.7 122.5 34.5 7.1 9.9 45.7 135.4 32.3 6.4 21.2 70.0 22.8 197.5 72.2 17.8 161.2 33.2 93.5 95.5 144.9 130.5 8.0 17.0 38.0 191.1 17.8 12.5 92.7 12.0 16.8 58.0 22.9 53.6 81.1 41.4 20.5 6.0 7.9 64.6 18.7 20.9 17.2 13.3 58.9 183.4 118.9 28.1 84.7 92.8 174.8 21.4 24.6 194.1 47.8 49.8 7.5 11.8 15.6 5.2 10.8 5.1 11.6 5.6 5.7 13.8 12.5 6.4 6.6 11.4 13.5 11.8 4.8 5.1 6.5 4.5 5.7 7.1 8.2 6.2 8.2 10.7 18.7 10.3 7.0 7.4 7.4 49.7 16.0 12.4 31.3 14.9 30.7 22.2 36.8 27.3 18.6 7.5 5.5 60.2 15.7 21.9 31.3 0.0 30.3 8.4 9.5 41.1 32.1 36.2 16.3 15.2 32.0 22.1 4.6 52.4 25.4 74.0 34.9 6.6 14.7 43.1 16.0 15.4 75.2 26.3 30.3 47.4 8.7 12.2 12.9 21.3 16.9 17.4 17.3 24.9 87.1 16.3 10.4 7.2 49.3 63.0 37.8 5.8 13.2 12.8 17.7 11.3 50.8 25.0 17.8 32.9 45.8 26.7 6.9 7.3 20.6 21.3 54.9 8.7 34.2 8.3 14.5 GBP4 Mpa2 ENSG00000162654 "Guanylate binding protein 4" Q96PP9 1 89181144-89198942 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 84.4;Endothelial cells: 81.2;Hepatic stellate cells: 92.4;Theca cells: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 12.1;HDLM-2: 9.9;HEL: 13.0;REH: 11.1;RT4: 18.3;U-266/70: 16.0" "HPA030101, HPA062039" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Plasma membrane" "HPA030101: AB_10601654, HPA062039: " "unprognostic (1.32e-2)" "unprognostic (3.89e-3)" "unprognostic (1.02e-2)" "unprognostic (1.07e-3)" "unprognostic (3.22e-1)" "unprognostic (9.93e-3)" "unprognostic (5.65e-2)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "prognostic favorable (9.29e-5)" "unprognostic (1.91e-3)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (1.22e-1)" "unprognostic (3.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.02e-3)" 11.3 5.2 4.0 29.5 3.9 6.6 6.7 4.4 4.8 4.2 2.6 6.6 12.4 8.8 4.5 7.2 9.1 8.8 11.0 3.8 4.3 9.8 14.1 31.2 34.3 7.1 3.7 16.4 1.6 6.5 2.7 11.9 7.7 5.8 7.2 3.4 7.1 6.7 7.1 2.1 11.8 7.7 3.9 29.0 11.9 2.9 4.4 10.0 7.8 9.4 11.0 13.1 4.5 3.9 0.8 0.0 0.1 0.3 0.1 0.1 0.6 1.8 7.6 8.0 7.2 0.1 12.1 0.6 1.0 2.3 0.6 0.9 0.0 0.3 0.4 9.9 0.1 13.0 0.4 0.3 1.0 0.2 0.3 0.4 0.0 0.1 0.0 1.2 1.9 0.3 0.4 2.3 0.0 0.2 6.6 0.3 0.4 0.1 0.1 11.1 0.2 0.4 0.1 18.3 0.2 0.5 0.3 0.7 0.3 0.6 0.5 1.4 0.4 0.3 1.6 0.2 0.2 16.0 0.3 0.3 0.3 0.1 2.3 0.6 4.1 0.4 7.1 14.1 6.1 2.5 7.6 7.9 2.2 3.3 5.6 5.2 5.6 13.8 14.5 0.9 9.0 5.5 4.0 3.9 4.4 4.8 3.8 4.3 7.1 3.7 7.7 3.9 4.4 3.9 84.4 32.1 39.3 0.0 28.3 4.6 9.1 20.7 1.8 2.8 3.5 2.4 3.6 8.6 25.3 5.5 8.4 0.9 29.0 5.1 0.0 2.2 1.9 4.8 8.4 81.2 0.0 11.2 0.5 3.3 1.6 22.2 9.2 7.4 21.5 17.9 92.4 6.5 8.3 0.0 2.5 4.3 4.1 29.2 10.9 1.2 3.7 33.7 5.4 15.9 33.8 15.5 36.0 1.0 0.6 36.3 1.9 1.9 7.2 24.4 4.4 1.5 43.3 12.2 0.0 5.3 11.3 2.4 3.4 2.9 3.0 1.5 34.2 122.6 2.4 13.6 GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Cell type enhanced" "Detected in many" "dendritic cells: 39.2;NK-cells: 75.2;Plasma cells: 22.9;T-cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 6.5;NB-4: 10.0;U-266/70: 20.7;U-937: 31.5" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" 3.7 3.3 0.4 73.9 0.5 34.9 4.6 0.4 1.7 3.1 1.5 6.9 5.8 2.3 1.4 2.6 3.1 11.5 2.0 0.4 0.5 2.0 11.1 19.1 54.4 2.9 0.7 2.7 1.1 0.7 1.0 2.8 1.2 2.3 8.0 0.2 4.8 1.2 0.7 1.0 9.0 6.1 0.5 42.7 9.2 4.0 0.8 12.4 2.3 0.9 23.3 12.7 1.4 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.7 1.2 1.2 0.0 0.1 0.1 6.5 5.3 2.6 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.9 0.6 3.0 0.3 0.0 0.0 10.0 1.4 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.6 1.3 0.1 0.0 0.0 4.0 0.1 0.5 0.5 0.0 2.2 20.7 0.5 0.1 0.2 31.5 0.0 0.9 15.3 1.1 97.5 38.0 150.4 4.8 63.1 89.3 6.7 6.0 23.2 35.8 97.9 53.4 44.9 0.7 243.8 38.4 0.4 0.5 0.4 1.7 0.4 0.5 2.9 0.7 1.2 0.5 0.8 0.7 2.1 6.4 5.1 0.0 12.4 0.0 0.2 0.5 0.6 0.0 0.4 0.4 0.7 1.5 4.2 0.0 4.2 0.1 39.2 0.1 0.0 0.0 0.4 3.7 0.4 2.8 0.0 0.8 0.0 1.1 0.0 1.5 2.0 3.9 10.8 0.2 4.6 0.6 4.0 0.0 0.7 0.0 0.0 18.9 1.4 0.2 0.0 17.1 0.0 2.8 10.4 2.9 75.2 0.0 0.0 1.3 0.0 0.0 22.9 0.4 0.0 0.3 8.0 0.4 0.0 0.9 0.9 0.1 2.9 0.9 0.0 0.1 72.9 11.0 0.1 0.1 GCHFR "GFRP, HsT16933" ENSG00000137880 "GTP cyclohydrolase I feedback regulator" P30047 15 40764068-40767708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 350.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 787.2;Hofbauer cells: 522.9;Proximal enterocytes: 620.8;Proximal tubular cells: 500.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 120.3;RPTEC TERT1: 146.6;SCLC-21H: 124.6" "Group enriched" "Detected in many" 5 "cerebellum: 10.3;midbrain: 11.8;pons and medulla: 9.4" HPA046258 Enhanced Supported Nucleoplasm NA NA 170000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA046258: AB_10967205" "unprognostic (2.50e-1)" "unprognostic (1.49e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-2)" "unprognostic (9.89e-3)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "prognostic favorable (5.62e-4)" "unprognostic (4.63e-2)" "unprognostic (1.67e-1)" "unprognostic (3.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.03e-3)" "unprognostic (9.28e-3)" "unprognostic (2.91e-2)" "unprognostic (1.84e-1)" "unprognostic (2.55e-1)" 37.4 20.1 13.6 8.9 13.3 19.5 34.5 17.4 20.1 16.1 18.5 18.7 38.8 6.5 2.2 57.2 15.8 10.0 10.9 13.1 14.5 73.5 350.1 46.4 24.7 18.2 67.3 19.2 15.3 9.8 12.2 6.6 33.7 19.4 6.9 4.2 22.3 3.2 4.5 31.1 60.7 1.7 13.5 13.0 16.4 3.3 15.9 23.0 12.8 7.4 19.5 12.2 17.6 12.2 0.3 7.7 6.2 33.3 9.5 3.4 16.7 2.2 7.8 3.7 7.4 90.7 49.7 46.0 31.1 1.9 2.4 6.1 16.4 3.1 0.8 36.2 26.2 45.5 65.3 120.3 7.7 29.9 15.2 7.8 3.8 1.6 0.6 2.9 14.4 3.7 23.2 13.2 1.1 17.2 7.9 60.4 16.0 8.2 56.5 64.7 0.5 28.8 146.6 24.2 124.6 1.9 20.1 87.7 10.4 8.1 25.3 30.0 0.0 0.6 1.2 2.2 0.3 0.9 6.0 28.9 4.9 66.3 4.0 18.0 73.3 102.4 76.8 23.6 129.0 48.2 67.1 71.1 48.7 31.2 68.3 44.7 11.7 132.6 22.4 90.4 144.4 109.0 13.6 13.3 17.4 20.1 13.1 14.5 18.2 67.3 33.7 13.5 15.9 12.2 24.3 3.2 54.0 0.3 24.9 14.5 21.6 72.2 8.6 2.5 81.4 48.0 0.1 84.4 87.0 64.4 12.5 161.9 25.9 75.7 76.3 52.5 0.6 46.2 4.9 13.7 60.6 24.4 1.6 32.7 37.0 10.1 16.3 35.7 44.4 12.2 31.4 787.2 522.9 0.0 1.7 74.4 111.9 56.1 18.5 0.5 17.7 71.9 67.6 0.0 29.0 26.1 102.0 0.0 0.4 18.7 161.8 8.6 12.8 25.6 620.8 500.2 58.3 22.4 0.0 4.7 12.4 2.9 12.5 79.7 14.9 36.5 49.2 1.7 125.3 40.8 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 447.4" "Cancer enhanced" "Detected in all" "urothelial cancer: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.4" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 32.1;MCF7: 50.6;OE19: 53.3;SK-BR-3: 165.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: AB_10794545, HPA041470: AB_10795121" "unprognostic (4.12e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (9.99e-2)" "unprognostic (2.53e-1)" "unprognostic (4.57e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.53e-1)" "unprognostic (8.86e-3)" "unprognostic (6.59e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.89e-9)" "unprognostic (3.11e-1)" "unprognostic (3.13e-1)" "unprognostic (1.12e-1)" "unprognostic (8.79e-3)" 7.1 2.4 6.1 6.0 6.1 1.8 5.4 6.8 11.4 18.7 5.9 25.9 8.4 5.3 9.3 45.6 5.7 2.5 5.2 6.0 6.1 17.9 2.1 6.4 4.2 7.5 6.1 6.8 2.2 0.4 4.8 11.4 8.0 5.7 17.2 6.5 9.0 2.2 2.1 11.0 10.2 5.2 6.3 9.0 18.8 1.8 6.1 4.1 4.7 0.9 20.9 5.4 19.1 6.8 21.8 0.3 5.2 1.5 1.6 5.5 5.5 0.6 1.3 1.8 1.7 1.0 15.2 0.6 2.9 1.5 0.6 1.8 1.6 0.5 1.8 2.5 4.0 0.2 1.0 32.1 1.0 0.7 1.3 0.2 1.6 4.5 0.3 4.1 5.1 4.2 1.0 2.3 2.2 50.6 1.5 2.0 2.6 53.3 0.6 6.3 1.4 7.1 2.6 7.4 1.1 2.2 0.2 165.0 0.5 1.6 3.0 2.7 2.7 0.9 1.1 1.9 1.8 2.7 0.9 1.5 4.2 2.7 0.7 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.1 0.0 6.1 6.1 6.8 11.4 6.0 6.1 7.5 6.1 8.0 6.3 6.1 6.8 5.9 6.4 1.1 1.6 1.0 1.3 0.9 4.4 1.2 1.6 4.1 3.0 1.5 0.0 22.2 5.5 0.0 24.2 1.2 98.2 5.9 0.9 67.8 2.6 3.8 4.3 3.5 0.0 0.6 1.3 71.9 2.1 30.1 4.1 0.0 2.0 3.9 0.3 3.1 1.7 0.8 34.2 6.1 1.9 1.0 447.4 3.4 1.4 1.8 1.9 1.2 0.6 0.0 1.5 1.2 19.2 36.7 3.0 0.1 1.1 46.0 100.6 9.0 1.7 6.6 0.6 2.7 1.4 1.3 5.1 2.0 9.3 1.9 1.3 13.9 4.8 GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" Neurogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 116.6;retina: 83.5" "Group enriched" "Detected in many" 4 "Bipolar cells: 60.9;Cone photoreceptor cells: 148.0;Early spermatids: 52.1;Late spermatids: 178.0;Rod photoreceptor cells: 88.4;Syncytiotrophoblasts: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Cell line enhanced" "Detected in many" "EFO-21: 32.8;fHDF/TERT166: 32.4;HDLM-2: 66.9;U-2 OS: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA065257: AB_2685447, HPA066762: AB_2685715, HPA069281: AB_2686107" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (9.97e-3)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-1)" "unprognostic (3.07e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.59e-9)" "unprognostic (8.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-1)" 31.0 8.7 19.5 4.8 22.1 12.8 24.6 17.4 12.9 12.4 6.0 7.3 2.7 17.9 1.8 3.3 10.3 4.3 9.5 10.5 14.5 7.8 8.1 15.2 6.7 14.2 27.0 7.3 38.1 0.8 19.1 14.0 10.2 11.5 1.6 83.5 21.3 5.3 13.1 7.4 10.0 6.5 7.4 116.6 4.8 38.9 42.1 3.1 7.7 8.7 4.7 12.6 9.9 12.4 2.1 7.5 3.2 3.7 2.2 1.1 11.1 2.3 3.1 1.1 0.7 10.0 4.4 14.2 32.8 32.4 8.1 4.7 4.0 3.8 0.6 66.9 3.1 2.6 11.7 21.2 3.2 1.6 10.7 2.4 2.0 0.8 1.6 3.2 26.7 12.7 4.7 6.3 1.5 4.5 3.9 7.1 5.7 3.7 10.6 4.5 0.9 3.9 0.9 3.6 1.7 1.2 4.8 18.3 9.3 4.1 2.7 6.3 7.9 7.5 30.4 5.8 2.6 1.6 0.3 2.8 1.7 8.5 0.8 7.7 0.8 0.5 1.2 0.3 1.7 0.6 1.3 0.9 0.2 0.2 0.7 0.9 0.1 0.0 0.0 0.7 2.0 0.5 19.5 22.1 17.4 12.9 10.5 14.5 14.2 27.0 10.2 7.4 42.1 12.4 4.2 6.4 0.0 1.6 5.4 1.0 0.3 0.7 0.6 60.9 3.6 3.4 3.0 1.5 1.3 0.0 148.0 3.2 9.1 0.5 0.0 4.2 52.1 1.0 10.4 7.0 0.0 8.2 5.0 9.3 1.5 6.6 1.1 1.5 4.5 1.6 20.7 2.4 1.9 5.0 15.8 0.7 0.0 2.8 3.7 178.0 5.9 3.1 5.4 8.4 4.9 8.9 1.0 1.0 0.8 4.7 0.3 2.6 5.0 0.8 0.3 0.1 0.8 88.4 0.0 4.6 1.9 12.9 8.2 0.1 1.1 46.0 7.0 0.9 2.0 0.6 GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 100.9;Cardiomyocytes: 108.2;Excitatory neurons: 133.2;Inhibitory neurons: 106.2;NK-cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Cell line enhanced" "Detected in many" "HEL: 30.5;HMC-1: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: AB_10602320" "unprognostic (5.00e-2)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.29e-5)" "unprognostic (8.49e-2)" "unprognostic (1.95e-3)" "unprognostic (1.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.34e-2)" "unprognostic (3.11e-2)" "unprognostic (6.49e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.72e-5)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (4.66e-3)" 10.5 2.0 14.3 2.8 21.6 12.7 9.6 11.2 26.1 5.0 0.0 6.2 1.8 3.6 0.8 8.6 4.4 4.3 16.7 24.5 3.7 2.3 7.2 9.7 4.3 3.0 1.5 1.5 1.5 1.7 3.5 3.9 2.3 4.0 2.8 2.1 3.6 1.4 12.0 5.5 6.5 4.9 0.6 8.8 7.9 0.6 2.5 3.0 2.7 9.7 4.2 6.2 5.8 16.9 12.5 1.3 1.0 2.1 1.7 1.8 1.3 1.0 0.5 0.7 0.4 0.4 0.9 16.8 16.6 1.2 1.0 10.9 3.4 5.4 0.7 1.2 6.0 30.5 7.2 6.6 2.4 9.0 46.3 0.9 4.1 1.6 4.5 2.6 9.5 4.5 0.9 1.5 1.3 4.1 2.0 5.2 1.8 4.3 3.3 6.9 2.1 8.8 0.6 2.4 5.5 1.0 4.0 0.7 4.0 2.1 0.9 0.9 12.2 1.6 3.2 3.5 5.6 13.4 8.3 19.8 1.4 5.3 0.4 0.2 0.4 15.5 1.5 0.9 0.2 2.7 0.2 0.7 0.2 1.9 0.1 0.5 0.3 13.1 0.9 0.1 0.1 1.0 14.3 21.6 11.2 26.1 24.5 3.7 3.0 1.5 2.3 0.6 2.5 16.9 100.9 0.0 1.8 33.0 14.3 20.3 4.9 14.5 19.9 43.8 7.4 3.7 108.2 10.0 14.4 0.0 0.0 1.5 46.1 18.2 0.0 5.3 0.1 3.8 1.0 49.0 8.4 31.2 133.2 3.1 34.7 9.1 2.0 8.0 4.5 0.2 51.4 19.5 2.5 1.7 106.2 11.2 8.2 15.7 31.3 0.3 2.5 21.4 12.4 42.2 4.7 2.1 142.2 58.8 56.6 30.5 31.7 1.2 14.5 3.1 10.6 0.3 13.6 2.7 13.1 19.9 17.5 0.0 3.3 34.6 22.4 0.7 23.4 1.0 4.4 4.7 GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;liver: 213.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.3;Hepatocytes: 141.3;Inhibitory neurons: 115.7;Oligodendrocyte precursor cells: 181.0" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HSkMC: 21.2;T-47d: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 2200000 24000000 "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" 84.7 5.6 1.8 1.7 2.1 0.2 30.1 1.7 1.7 5.2 2.3 5.8 1.1 4.5 4.6 3.9 5.4 5.2 8.9 1.8 5.6 11.8 213.3 4.0 1.3 1.0 2.0 7.5 2.1 5.5 1.2 4.8 1.4 11.1 5.7 0.4 3.7 4.7 45.7 5.6 4.3 4.0 1.1 4.0 6.1 1.7 3.4 2.3 4.6 11.6 0.9 5.0 5.8 1.4 0.0 0.0 0.6 5.0 3.3 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.3 4.3 0.0 0.0 2.6 0.0 0.1 0.0 0.6 0.0 0.0 21.2 7.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 3.5 0.6 56.0 0.1 3.0 4.8 2.1 2.6 0.5 0.5 0.0 0.0 0.5 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.7 1.7 1.8 5.6 1.0 2.0 1.4 1.1 3.4 1.4 17.2 0.0 0.5 14.7 0.4 4.7 4.5 17.8 10.2 0.6 9.7 16.0 18.6 1.5 1.9 1.8 0.0 17.4 0.5 2.8 1.9 0.0 5.1 0.5 9.4 4.8 3.0 5.3 53.3 0.2 2.2 23.8 0.5 0.3 0.0 1.1 6.1 141.3 1.9 0.0 115.7 1.9 0.0 3.0 1.8 2.8 18.6 0.7 1.8 36.5 0.0 0.7 0.0 181.0 3.6 0.2 1.7 12.0 0.0 5.2 0.0 9.6 0.6 0.4 13.1 18.7 15.1 0.7 0.3 2.9 3.7 40.2 0.5 49.4 2.2 0.9 GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.8;Endothelial cells: 109.9;Hepatic stellate cells: 117.8;Kupffer cells: 109.1;monocytes: 74.9;NK-cells: 185.3;T-cells: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 14.7;MOLT-4: 9.2;TIME: 3.9" "Low region specificity" "Detected in many" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" 9.8 2.5 3.0 11.0 3.0 1.0 7.9 2.9 3.5 3.8 3.0 3.7 3.5 4.6 1.1 2.1 4.4 3.2 9.3 2.8 2.9 3.5 2.4 8.9 19.6 3.5 3.2 1.5 1.4 1.5 1.1 7.1 3.4 2.3 2.2 0.1 2.5 2.0 5.4 2.5 6.9 3.8 3.5 24.7 3.3 0.8 3.6 6.6 5.3 7.1 8.4 3.5 3.0 3.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.7 1.9 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 32.2 0.1 43.8 29.6 51.1 0.3 47.5 54.2 13.5 0.6 68.2 56.2 2.7 42.6 30.6 0.8 34.0 35.0 3.0 3.0 2.9 3.5 2.8 2.9 3.5 3.2 3.4 3.5 3.6 3.2 189.8 3.2 1.5 0.0 5.1 5.5 0.6 0.0 1.2 0.6 1.9 3.6 5.9 2.8 0.6 0.0 0.0 0.3 51.5 0.1 0.0 0.3 0.3 0.4 0.6 109.9 0.0 10.5 0.0 0.4 0.3 3.7 1.5 0.2 8.2 0.2 117.8 2.0 37.9 0.0 0.0 0.0 0.0 109.1 7.6 1.3 1.5 48.0 8.8 0.0 74.9 0.3 185.3 0.0 0.0 0.1 0.1 0.0 7.6 0.7 0.2 0.5 0.0 1.0 0.0 2.5 3.5 0.3 0.5 0.7 3.1 0.4 97.3 1.0 0.0 0.7 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Cell type enhanced" "Detected in many" "Adipocytes: 67.4;Endothelial cells: 66.0;Hepatic stellate cells: 86.0;Kupffer cells: 75.1;Microglial cells: 32.8;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 59.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" 20.3 5.7 4.4 21.3 5.0 0.7 16.0 4.7 5.5 9.8 5.5 6.7 6.8 10.4 3.1 4.3 9.0 7.5 17.4 4.1 4.5 8.3 9.4 27.0 23.2 5.4 4.9 3.5 2.8 4.6 2.6 15.4 5.4 4.9 7.2 0.3 4.3 5.3 9.8 4.7 10.5 12.7 5.4 40.6 5.0 2.0 5.1 7.3 11.9 15.1 13.5 8.4 5.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 59.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.7 0.0 9.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.5 45.2 0.0 15.3 59.0 17.4 0.5 14.8 13.9 13.0 0.0 16.7 13.6 4.8 15.5 57.4 0.7 7.7 26.8 4.4 5.0 4.7 5.5 4.1 4.5 5.4 4.9 5.4 5.4 5.1 5.8 67.4 3.2 5.3 0.3 0.8 3.1 0.5 0.0 1.8 0.0 0.4 0.8 5.5 5.7 0.0 1.8 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.1 66.0 0.0 1.3 0.1 0.0 0.0 2.3 0.5 0.2 3.8 0.0 86.0 1.6 6.8 0.0 0.1 0.0 0.0 75.1 2.8 0.9 0.3 21.9 0.0 32.8 44.2 0.0 19.6 0.0 0.1 0.0 0.0 0.0 2.2 0.9 0.0 0.2 1.5 0.0 0.0 1.5 1.2 0.2 0.4 0.5 1.7 0.1 11.1 0.2 0.0 0.4 GINS3 "FLJ13912, PSF3" ENSG00000181938 "GINS complex subunit 3" Q9BRX5 16 58295080-58406147 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-698: 146.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041216, HPA048209" Uncertain Enhanced Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA041216: AB_10794989, HPA048209: AB_2680314" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-3)" "unprognostic (6.34e-2)" "unprognostic (4.70e-2)" "unprognostic (2.82e-1)" "unprognostic (1.75e-4)" "unprognostic (7.76e-2)" "unprognostic (1.76e-3)" "unprognostic (7.19e-2)" "unprognostic (4.50e-2)" "unprognostic (2.67e-3)" "unprognostic (1.14e-7)" "unprognostic (9.76e-3)" "unprognostic (5.34e-2)" "unprognostic (8.23e-2)" "unprognostic (1.07e-2)" 4.3 7.4 2.0 4.2 4.2 8.4 3.7 3.7 2.6 3.7 2.2 5.8 3.2 2.8 3.7 9.1 2.4 1.5 6.2 2.4 2.5 2.5 2.6 2.1 7.8 3.0 3.5 1.3 1.7 3.7 2.0 3.7 2.7 2.2 4.2 1.8 3.4 4.6 1.8 4.5 2.8 3.8 2.8 5.4 2.6 6.8 3.2 8.8 1.9 4.9 8.0 3.0 6.7 2.7 20.2 22.4 26.5 14.3 2.9 3.7 13.3 22.4 9.8 35.4 26.8 16.9 20.2 35.0 17.5 7.6 26.3 18.7 24.5 18.8 39.6 19.5 30.4 20.4 12.0 20.5 1.6 26.1 33.7 4.2 3.5 18.4 6.3 7.9 24.4 28.9 33.5 14.4 15.0 20.9 48.1 24.2 24.5 17.2 45.3 82.6 29.4 44.4 12.8 12.6 30.3 20.1 37.3 24.3 12.8 10.6 12.9 21.4 10.4 23.5 27.8 14.2 28.4 14.3 20.2 146.3 16.2 26.1 29.3 0.1 1.8 0.1 1.9 1.6 1.5 2.5 1.6 2.9 4.1 4.4 1.5 2.5 0.4 4.1 1.0 8.2 2.4 1.5 2.0 4.2 3.7 2.6 2.4 2.5 3.0 3.5 2.7 2.8 3.2 2.7 3.9 0.0 2.6 9.1 3.2 1.8 4.9 2.7 4.0 1.5 2.0 1.7 4.1 0.0 1.4 0.0 2.1 9.1 4.5 1.6 0.0 3.7 20.7 1.8 2.1 4.3 0.0 12.4 0.6 2.0 7.6 2.5 1.5 7.9 1.3 6.9 3.6 0.8 2.8 5.0 0.2 0.9 0.0 1.6 1.1 9.2 1.5 1.9 1.8 2.8 2.6 1.8 2.1 5.0 1.2 1.9 0.3 1.2 6.2 1.7 0.2 0.5 1.1 1.8 6.6 1.6 3.0 4.6 8.7 13.0 2.4 3.1 2.4 3.2 2.8 4.9 GIPC2 "FLJ20075, SEMCAP-2" ENSG00000137960 "GIPC PDZ domain containing family member 2" Q8TF65 1 77979542-78138444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.0;kidney: 41.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 122.1;Proximal tubular cells: 267.7;Undifferentiated cells: 63.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.1;HaCaT: 6.0;Hep G2: 23.0;HUVEC TERT2: 23.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051212, HPA062684" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA051212: , HPA062684: AB_2684833" "unprognostic (1.72e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.49e-4)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.35e-1)" "unprognostic (7.63e-2)" "unprognostic (2.22e-1)" "unprognostic (5.91e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.11e-6)" "unprognostic (6.55e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-2)" "unprognostic (1.29e-1)" 3.9 23.8 0.5 1.7 0.4 0.3 3.0 0.4 0.5 1.8 0.5 15.6 38.0 2.1 0.9 2.1 3.1 5.5 1.5 0.5 0.4 41.4 18.4 2.7 0.8 0.4 0.4 2.4 18.1 2.3 0.9 3.5 0.4 1.7 14.9 0.1 4.2 0.9 1.1 4.7 38.0 2.8 0.4 27.9 6.0 1.0 0.5 0.4 1.0 1.6 0.8 2.0 1.9 0.4 0.0 0.0 0.0 0.1 2.4 6.1 0.0 1.0 0.0 0.5 1.1 5.1 3.3 1.5 0.1 0.5 0.0 6.0 0.0 0.0 3.2 0.2 0.0 0.8 0.0 23.0 1.2 0.0 0.0 1.0 0.1 3.5 0.1 0.0 23.5 0.0 0.0 0.1 2.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.5 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.4 33.6 0.0 1.3 2.0 2.0 12.9 2.4 0.9 4.0 0.4 5.2 1.5 3.2 27.1 2.5 9.2 2.1 6.7 0.0 43.7 33.2 11.8 2.5 13.3 0.9 21.6 3.0 0.4 14.7 33.0 3.1 2.9 8.6 7.2 0.0 5.9 22.9 43.3 13.2 0.0 15.2 34.4 0.0 0.8 1.9 1.2 1.2 2.1 0.0 14.0 1.0 0.0 0.0 4.5 8.9 16.5 39.3 0.0 0.0 0.8 122.1 267.7 11.7 0.5 0.0 1.3 1.3 0.6 2.5 7.9 21.7 1.6 1.3 32.4 63.8 6.0 GIPC3 "C19orf64, DFNB15, DFNB72, DFNB95" ENSG00000179855 "GIPC PDZ domain containing family member 3" Q8TF64 19 3585478-3593541 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.7" "Group enriched" "Detected in some" 4 "Adipocytes: 10.4;Endothelial cells: 6.2;Hepatic stellate cells: 12.8;Rod photoreceptor cells: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 19.0;HMC-1: 11.8;THP-1: 23.1;WM-115: 44.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA067765 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA067765: " "unprognostic (1.77e-1)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (6.99e-2)" "unprognostic (1.22e-1)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (3.67e-3)" "unprognostic (4.76e-2)" "unprognostic (2.97e-1)" "unprognostic (5.06e-3)" "unprognostic (2.26e-2)" "unprognostic (1.51e-3)" "unprognostic (1.96e-2)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (9.06e-2)" 4.6 2.2 1.4 1.0 1.0 0.3 2.8 1.0 1.1 3.0 0.8 1.9 1.2 2.8 2.9 5.2 2.1 2.1 3.9 1.2 1.2 3.6 1.4 3.8 2.4 1.6 1.2 0.7 0.7 2.7 1.0 1.1 1.6 3.5 1.4 16.7 0.7 2.3 1.7 1.1 4.4 8.3 1.4 3.9 2.0 0.3 1.6 3.1 3.0 1.9 1.6 1.1 1.8 1.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.9 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.4 0.0 1.5 0.0 0.2 6.9 19.0 0.0 0.7 0.0 11.8 0.2 0.0 1.1 0.0 0.0 2.1 0.2 3.2 0.0 0.3 0.0 0.0 1.1 0.7 0.0 1.2 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.5 0.0 4.7 1.1 0.0 23.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 44.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.0 1.1 1.2 1.2 1.6 1.2 1.6 1.4 1.6 1.1 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.4 0.1 0.3 2.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 12.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.2 1.1 0.0 0.4 0.1 0.3 0.1 0.3 0.1 0.0 0.1 GJA4 CX37 ENSG00000187513 "Gap junction protein alpha 4" P35212 1 34792999-34795747 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 234.2;Sertoli cells: 664.0;Smooth muscle cells: 306.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 74.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047981 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047981: AB_2680228" "unprognostic (2.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.12e-2)" "unprognostic (2.67e-2)" "unprognostic (4.48e-1)" "unprognostic (5.24e-3)" "prognostic favorable (3.28e-4)" "unprognostic (2.01e-2)" "unprognostic (2.23e-1)" "unprognostic (8.17e-2)" "unprognostic (6.83e-2)" "unprognostic (8.81e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.47e-2)" "unprognostic (3.74e-2)" "unprognostic (3.82e-3)" "unprognostic (7.96e-3)" 79.4 20.4 10.1 9.3 11.0 0.3 61.5 9.8 15.1 26.6 9.0 14.7 2.8 33.8 5.5 7.5 40.0 17.3 83.6 10.5 9.6 35.8 17.3 40.7 11.3 10.3 10.2 18.0 7.0 10.6 6.4 61.6 10.6 18.8 3.8 0.8 10.1 10.7 34.7 14.8 13.9 15.2 10.2 9.9 12.9 5.4 10.2 2.7 39.8 35.2 5.4 28.1 22.4 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.1 11.0 9.8 15.1 10.5 9.6 10.3 10.2 10.6 10.2 10.2 9.9 90.4 0.0 0.0 0.3 0.6 9.7 1.9 0.2 1.2 0.2 1.1 1.5 9.0 1.5 0.6 3.7 0.0 0.2 0.7 0.0 0.0 11.0 0.1 3.1 0.5 81.4 15.6 2.7 0.0 0.0 0.1 7.7 2.6 4.9 0.0 0.5 234.2 1.8 0.3 0.0 0.0 0.0 0.0 6.3 10.7 1.1 0.9 2.2 19.6 1.0 0.6 0.1 0.0 0.0 0.0 1.0 0.0 12.8 0.2 3.0 0.0 0.1 1.2 0.7 664.0 4.4 306.3 0.2 1.2 0.7 8.7 0.0 1.3 1.6 0.1 5.2 GJC3 "CX30.2, GJE1" ENSG00000176402 "Gap junction protein gamma 3" Q8NFK1 7 99923266-99929620 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 8.7;pancreas: 11.1;salivary gland: 11.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 36.3;Breast myoepithelial cells: 26.9;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 12.8;Prostatic glandular cells: 13.0" "Group enriched" "Detected in many" 5 "breast cancer: 3.8;melanoma: 3.0;prostate cancer: 3.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.3;SK-MEL-30: 2.3;U-2197: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015024 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" "HPA015024: AB_1847132" "unprognostic (9.31e-2)" "unprognostic (6.43e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-2)" "unprognostic (2.54e-1)" "unprognostic (2.88e-2)" "unprognostic (7.68e-2)" "unprognostic (9.14e-2)" "unprognostic (6.71e-2)" "unprognostic (4.78e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-3)" "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (3.49e-1)" "unprognostic (5.81e-3)" 1.6 0.5 0.8 0.1 0.9 0.1 8.7 0.1 1.2 0.3 0.0 0.5 0.4 0.2 0.0 0.2 0.3 0.3 0.4 0.9 0.3 1.0 2.7 0.2 0.2 0.2 0.4 0.4 11.1 0.0 0.4 1.0 0.2 4.6 0.0 1.0 11.7 0.1 0.2 2.6 0.3 0.2 0.0 0.3 1.4 1.7 0.6 0.1 0.3 0.2 0.0 0.3 0.3 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.5 0.6 0.1 0.5 0.2 0.4 1.1 1.3 0.0 0.0 0.4 0.3 0.0 0.4 0.1 0.2 0.1 0.3 2.3 0.5 0.7 0.0 0.3 0.1 0.4 1.8 0.1 0.1 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.9 0.1 1.2 0.9 0.3 0.2 0.4 0.2 0.0 0.6 0.5 1.1 3.2 3.7 0.0 0.4 0.3 4.9 1.4 0.0 0.0 36.3 26.9 0.0 4.3 2.1 1.8 0.0 0.0 0.6 0.0 1.9 0.4 0.4 0.0 0.0 1.5 1.2 0.0 0.7 24.0 0.0 0.2 0.0 0.0 4.5 0.2 1.1 5.0 0.1 0.0 0.4 0.1 8.2 0.0 0.3 1.1 0.3 0.1 0.0 0.0 0.6 4.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 13.0 0.0 9.7 0.3 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 9.4 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532467-6645729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 173.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 31.3;Cytotrophoblasts: 79.0;Extravillous trophoblasts: 41.6;Hepatocytes: 120.5;Oligodendrocyte precursor cells: 52.3;Proximal tubular cells: 31.6;Syncytiotrophoblasts: 46.0" "Cancer enhanced" "Detected in many" "testis cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 235.7;CACO-2: 58.2;HMC-1: 45.6;RPTEC TERT1: 95.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria NA NA 740000 "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA002318: AB_1849700, HPA052887: AB_2681980" "unprognostic (6.73e-2)" "unprognostic (1.19e-1)" "unprognostic (6.50e-2)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-3)" "unprognostic (1.17e-2)" 0.3 0.3 15.3 1.4 15.5 0.5 0.8 14.7 23.7 0.4 12.9 1.0 0.8 0.4 5.2 3.2 0.7 0.8 0.1 14.8 14.4 38.2 173.5 1.0 1.6 14.0 13.6 0.3 0.1 0.0 4.9 15.2 13.4 0.5 0.4 1.6 1.1 1.0 1.3 4.5 0.8 0.0 13.1 1.2 1.0 3.5 15.8 0.0 5.1 0.1 1.2 1.1 0.1 15.3 0.6 4.9 2.1 25.6 0.2 0.4 235.7 0.1 0.0 0.0 0.1 58.2 0.5 0.3 5.6 0.1 0.7 0.4 0.0 0.7 0.2 1.2 13.4 0.2 0.3 38.3 0.0 0.1 45.6 0.0 0.1 1.8 0.3 1.0 9.0 4.3 0.0 0.5 1.2 1.5 0.9 0.2 27.5 4.6 3.8 1.3 0.0 0.5 95.4 1.0 22.6 11.7 0.0 21.4 0.3 13.9 5.3 0.1 3.0 0.6 0.6 2.6 1.3 1.1 34.4 0.1 0.8 2.4 5.1 0.4 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.0 0.3 15.3 15.5 14.7 23.7 14.8 14.4 14.0 13.6 13.4 13.1 15.8 15.3 0.2 0.0 0.0 17.6 1.9 0.0 0.0 0.2 1.2 0.4 1.5 0.6 0.7 11.5 0.1 31.3 0.0 79.0 0.2 0.0 5.9 0.0 12.6 5.4 0.5 0.6 0.0 0.0 21.6 0.2 41.6 0.3 0.0 10.7 0.0 1.1 2.2 120.5 7.0 0.0 15.9 0.0 0.0 2.8 0.3 10.8 0.3 0.4 0.0 1.9 0.0 9.6 0.0 52.3 1.8 0.1 0.0 0.0 15.1 0.0 0.0 31.6 0.0 0.4 0.0 1.7 0.8 4.5 5.1 0.4 0.0 46.0 0.8 0.0 0.0 0.1 GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus" NA NA 2100000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "HPA010815: AB_2232486" "unprognostic (3.70e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (7.42e-2)" "unprognostic (3.30e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-3)" "unprognostic (5.13e-3)" "unprognostic (9.45e-3)" "unprognostic (8.46e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-2)" "prognostic favorable (1.56e-7)" "unprognostic (3.54e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-4)" 42.7 36.8 25.0 17.4 26.3 9.0 40.3 24.0 25.7 53.3 17.3 44.5 17.3 57.8 22.4 30.9 46.7 20.4 50.5 24.7 27.5 42.6 25.6 38.2 16.3 27.0 29.0 69.0 58.1 34.3 38.9 24.9 25.2 37.5 18.7 20.3 36.1 24.9 53.8 35.2 36.4 29.9 25.0 35.1 36.3 40.6 29.5 20.0 43.1 16.4 18.9 42.3 40.8 30.0 38.4 52.2 44.7 43.3 113.7 113.2 42.8 45.0 64.2 48.6 68.3 34.4 116.0 22.8 59.8 102.9 35.8 71.1 30.1 62.1 80.1 10.3 26.1 17.9 37.8 54.3 70.5 29.3 12.6 68.0 32.8 63.6 66.3 91.3 100.8 54.8 19.0 24.9 44.2 70.0 14.1 26.0 34.7 81.2 20.6 33.9 32.6 59.5 31.6 17.1 15.8 23.3 87.3 24.9 25.0 47.7 28.2 36.5 79.1 46.1 40.9 48.2 30.3 47.4 51.2 41.1 86.3 22.5 46.6 3.2 16.7 13.3 19.1 15.7 19.2 11.6 23.8 20.9 18.5 10.1 28.2 22.6 7.3 15.4 19.9 18.4 21.0 19.0 25.0 26.3 24.0 25.7 24.7 27.5 27.0 29.0 25.2 25.0 29.5 30.0 52.8 64.1 50.7 114.3 46.4 27.1 27.2 33.0 55.8 68.5 35.6 35.6 79.5 77.2 39.7 51.5 146.0 78.0 75.6 33.5 7.9 39.9 39.7 49.2 79.3 62.0 38.6 25.0 133.4 42.5 43.6 101.4 38.7 58.0 3.8 91.0 75.3 40.7 50.1 70.7 155.3 31.9 24.4 68.8 42.1 28.1 96.9 44.4 42.7 62.8 64.8 59.6 111.2 97.5 137.3 40.8 28.8 114.3 100.2 33.6 47.8 44.2 44.3 57.9 92.1 84.6 59.9 89.2 87.9 30.5 21.6 75.2 72.4 72.4 32.9 26.4 GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA029121: AB_10600794" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (5.68e-2)" "unprognostic (4.22e-3)" "unprognostic (3.71e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.35e-5)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (9.21e-3)" "unprognostic (1.33e-1)" "unprognostic (7.66e-3)" "unprognostic (7.68e-3)" "unprognostic (3.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" 33.9 68.3 11.8 17.1 12.8 19.4 25.6 12.9 15.4 38.1 21.1 24.6 30.3 24.4 23.2 29.8 21.1 44.7 18.1 11.7 13.9 52.2 59.8 28.9 22.6 13.6 13.6 22.0 27.0 29.4 19.7 48.0 15.0 57.3 21.1 2.7 35.2 20.4 7.4 29.2 26.9 24.5 12.4 32.3 28.8 6.4 16.0 12.2 23.6 9.6 15.4 36.0 26.8 14.4 22.7 40.8 3.9 27.0 224.8 121.7 27.5 40.8 172.0 58.1 79.0 50.9 68.7 0.0 83.2 59.0 1.9 14.6 0.6 30.0 18.4 4.6 41.8 7.0 22.9 60.6 101.4 19.7 58.1 119.9 36.0 55.9 17.9 85.1 89.0 17.6 32.8 3.1 34.6 28.5 10.1 0.1 46.5 56.9 20.9 17.4 0.0 74.3 53.7 24.5 12.9 42.2 27.1 76.4 120.6 45.6 38.3 54.2 45.7 25.7 5.0 46.2 26.9 24.9 45.9 11.3 44.0 15.7 36.3 35.0 71.3 12.2 23.4 74.5 21.7 13.1 23.0 20.5 31.8 7.7 22.7 21.7 19.4 18.0 55.6 21.3 43.4 36.9 11.8 12.8 12.9 15.4 11.7 13.9 13.6 13.6 15.0 12.4 16.0 14.4 11.7 3.2 19.1 3.3 7.3 0.0 16.4 0.0 10.8 2.0 12.3 11.6 5.8 31.5 5.0 31.3 0.0 70.3 7.6 13.8 27.4 51.3 0.6 8.5 19.1 17.5 10.9 18.5 1.6 38.3 68.5 33.4 18.8 14.2 8.8 14.9 42.8 69.8 197.7 1.7 1.9 19.4 0.0 66.8 0.0 1.4 16.4 41.1 0.0 1.0 29.8 21.0 13.4 2.0 3.9 29.8 22.2 13.9 23.0 28.9 44.9 67.3 5.8 1.5 13.1 11.9 17.1 0.9 1.9 17.8 0.0 69.6 9.3 17.6 11.8 18.7 GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 6.4;Leydig cells: 3.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 78.1" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" 8.1 0.3 0.4 0.7 3.0 0.0 0.8 0.0 3.6 6.0 0.0 13.5 9.9 1.2 0.0 0.7 1.6 12.2 0.6 3.2 0.0 0.3 2.7 1.0 0.6 0.0 0.2 0.4 1.6 0.0 0.0 1.1 0.0 0.1 6.0 3.4 0.0 0.1 0.1 0.1 8.2 1.9 0.0 0.1 3.7 0.4 0.0 0.1 0.2 0.2 0.2 11.8 1.5 1.7 0.0 16.6 0.0 0.0 0.8 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 78.1 0.6 1.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 3.6 3.2 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 6.4 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 23.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLRA3 ENSG00000145451 "Glycine receptor alpha 3" O75311 4 174636920-174829247 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 10.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 25.3;Early spermatids: 24.7;Excitatory neurons: 52.4;Inhibitory neurons: 11.2;Late spermatids: 22.8" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.75e-3)" "unprognostic (3.14e-1)" "unprognostic (1.78e-2)" "unprognostic (1.36e-1)" "unprognostic (9.02e-2)" "unprognostic (3.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.12e-2)" "unprognostic (4.26e-2)" "unprognostic (1.64e-5)" "unprognostic (4.61e-4)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" 0.0 0.8 4.2 0.0 3.4 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.5 0.0 0.0 0.0 0.2 0.8 3.6 0.0 0.4 0.0 0.6 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.5 10.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.2 3.4 0.0 3.0 2.6 4.5 0.8 3.6 0.6 0.9 10.5 0.0 0.0 0.0 0.6 1.3 1.6 0.0 1.3 0.0 0.0 5.0 25.3 0.3 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.1 0.4 0.0 0.0 52.4 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.0 2.8 0.0 0.2 0.0 1.0 1.0 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.6 0.0 1.0 0.3 0.7 1.6 0.1 0.1 0.0 0.3 0.0 0.0 0.4 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 294.1;Hepatocytes: 402.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 555.0" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 70.1 93.0 217.2 44.8 219.0 29.2 96.4 180.4 216.8 50.2 135.8 63.4 80.9 48.1 30.0 77.0 47.4 53.3 75.6 193.3 223.2 249.2 816.4 57.7 42.9 220.9 222.9 71.6 66.2 39.0 37.1 58.8 202.3 110.5 61.5 90.2 55.6 53.2 51.1 84.2 88.6 53.3 223.2 46.4 57.0 22.3 254.6 44.8 68.1 64.4 59.2 68.1 55.6 202.3 127.1 100.3 77.1 131.5 143.0 174.5 84.0 97.7 167.8 92.4 100.5 233.0 120.6 141.5 77.8 143.4 53.0 194.7 101.4 98.5 98.0 102.7 79.8 69.0 55.9 555.0 318.1 163.2 95.5 121.3 181.5 103.2 304.9 140.3 112.0 109.3 70.7 124.0 101.0 92.1 148.1 145.7 88.2 136.9 79.8 110.4 98.3 93.1 267.4 101.8 39.7 73.9 87.8 68.8 126.1 73.9 94.3 112.8 112.4 47.8 42.5 98.2 101.0 73.6 81.4 167.5 115.3 182.8 29.3 9.1 14.2 9.7 8.3 11.1 10.3 9.8 11.2 10.1 15.9 11.3 9.9 8.0 1.2 13.6 16.0 5.9 12.6 6.5 217.2 219.0 180.4 216.8 193.3 223.2 220.9 222.9 202.3 223.2 254.6 202.3 49.3 22.4 23.9 294.1 56.6 106.0 57.5 32.2 105.3 22.5 83.3 38.2 60.2 57.2 47.3 60.7 37.5 95.7 45.6 56.1 156.5 32.5 14.2 37.3 44.0 54.1 39.4 52.6 35.8 33.8 63.8 89.0 86.2 59.7 43.2 33.6 50.7 402.3 69.1 15.2 38.0 49.5 36.7 74.1 184.5 26.0 88.0 81.4 104.9 42.2 50.6 140.0 39.1 48.7 42.9 50.2 38.3 90.7 75.7 103.4 124.2 175.5 21.6 68.9 65.7 41.3 55.9 11.4 8.6 189.5 122.3 47.6 84.6 70.9 49.6 107.3 GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.9;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Cytotrophoblasts: 4.6;Early spermatids: 2.6;Hepatocytes: 4.6;Proximal tubular cells: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.7;K-562: 4.3;OE19: 2.1;SK-MEL-30: 5.5;THP-1: 2.7;WM-115: 6.0" "HPA042492, HPA044839, HPA061369" Uncertain Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.44e-1)" "unprognostic (5.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-1)" "unprognostic (2.35e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (4.77e-3)" "unprognostic (5.96e-2)" 1.7 1.7 0.0 0.1 0.3 0.0 1.2 0.0 0.8 0.4 0.5 0.5 0.0 0.4 1.7 0.5 0.4 0.4 0.9 0.4 0.0 1.6 3.9 0.5 0.1 0.0 0.0 0.4 1.0 0.5 0.4 0.8 0.0 0.4 0.0 0.1 0.6 0.2 0.5 0.6 0.4 0.1 0.0 0.1 0.6 15.4 0.1 0.0 0.4 0.1 0.1 0.4 0.4 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.8 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.1 1.2 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.8 0.0 0.0 2.3 0.1 0.0 0.5 0.0 0.6 0.0 0.4 0.1 2.6 0.0 0.0 0.0 2.1 4.6 0.1 0.1 1.9 0.2 2.6 0.6 0.8 0.9 0.0 0.0 1.2 0.4 0.5 0.8 0.0 0.5 0.0 0.1 0.0 4.6 0.5 0.0 0.4 0.1 0.0 1.2 0.3 2.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.2 3.3 0.0 0.1 0.0 0.9 0.4 1.2 1.0 0.1 0.1 2.5 0.3 0.7 0.2 0.3 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182378098-182392206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1443.6" "Group enriched" "Detected in all" 4 "Late spermatids: 8544.2;Muller glia cells: 6247.0" "Cancer enhanced" "Detected in all" "liver cancer: 365.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 656.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 656.8" "Cell line enhanced" "Detected in many" "ASC diff: 1150.8;ASC TERT1: 807.6;HSkMC: 702.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 753.5 76.0 694.3 156.9 746.5 232.9 573.5 717.5 1237.1 161.4 583.2 157.8 24.4 116.7 115.7 218.7 224.3 105.4 129.7 676.6 764.7 65.3 280.7 221.7 75.2 891.0 783.7 303.0 204.7 32.3 70.5 176.6 767.0 103.4 92.5 891.1 233.5 96.0 1443.6 231.4 148.2 124.1 725.0 216.4 648.2 87.1 811.4 97.0 257.4 472.0 103.2 185.5 292.0 810.4 26.4 10.8 117.2 0.2 1150.8 807.6 86.0 44.1 141.7 25.9 23.4 64.1 26.7 22.4 46.3 85.5 23.8 59.3 51.8 309.4 21.5 61.2 143.3 296.5 47.6 124.8 61.1 132.6 227.2 702.1 363.3 32.9 384.6 39.1 52.8 71.7 254.3 13.3 92.6 15.0 208.2 126.5 87.3 36.8 55.0 74.3 31.3 38.6 45.8 114.0 79.7 52.5 12.4 157.3 17.4 93.3 153.1 165.9 39.7 0.9 1.9 0.8 10.1 4.8 3.4 0.4 22.3 73.9 5.0 396.5 153.4 409.4 42.3 145.8 17.6 11.5 29.9 35.5 80.0 17.8 15.3 25.3 656.8 27.2 130.5 43.7 13.0 172.0 694.3 746.5 717.5 1237.1 676.6 764.7 891.0 783.7 767.0 725.0 811.4 810.4 127.8 125.0 173.8 599.4 37.6 134.7 533.8 1190.7 260.0 105.6 166.6 99.1 216.2 171.6 855.3 82.8 52.1 161.7 113.4 118.3 74.3 124.2 1491.3 140.2 150.0 191.5 325.9 319.7 3.4 116.6 65.9 404.4 388.4 124.6 786.3 88.0 152.8 597.1 798.0 43.7 22.0 256.7 451.6 907.2 614.1 8544.2 487.4 687.4 136.9 74.9 112.7 6247.0 42.2 38.2 330.0 108.1 105.3 375.0 38.7 421.0 10.3 46.6 569.9 176.0 92.1 481.5 218.5 48.2 63.6 186.5 128.3 235.3 108.6 53.3 173.3 1420.5 GLYAT "ACGNAT, GAT" ENSG00000149124 Glycine-N-acyltransferase Q6IB77 11 58640426-58731974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "kidney: 571.8;liver: 698.0" "Group enriched" "Detected in some" 6 "Hepatocytes: 346.7;Proximal tubular cells: 1261.0" "Group enriched" "Detected in some" 158 "liver cancer: 21.7;renal cancer: 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-937: 1.4" "Not detected" "Not detected" "HPA040251, HPA044094" Enhanced NA NA 21000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA040251: AB_2676902, HPA044094: AB_2678807" "unprognostic (2.15e-2)" "unprognostic (9.38e-4)" "unprognostic (4.60e-2)" "unprognostic (1.65e-3)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.69e-1)" 47.0 0.1 0.0 0.1 0.1 0.1 8.5 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 571.8 698.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 11.5 0.0 31.3 0.0 0.1 0.0 0.0 123.3 0.0 6.0 0.0 0.0 0.6 0.0 8.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 346.7 0.0 0.0 0.2 0.0 0.0 10.7 0.0 8.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1261.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 GLYCTK "HBEBP2, HBEBP4" ENSG00000168237 "Glycerate kinase" Q8IVS8 3 52287089-52295257 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 275.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 183.0;Proximal enterocytes: 105.2;Proximal tubular cells: 83.0" "Cancer enriched" "Detected in all" 6 "liver cancer: 52.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006913 Approved Approved "Golgi apparatus,Cytosol,Rods & Rings" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Golgi apparatus, Rods & Rings" "HPA006913: AB_1078993" "unprognostic (1.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.64e-4)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (3.36e-3)" "unprognostic (2.15e-1)" "unprognostic (3.30e-2)" "unprognostic (3.42e-1)" "unprognostic (3.77e-1)" "unprognostic (3.82e-2)" "unprognostic (9.00e-3)" 14.8 8.3 1.0 4.5 0.9 6.7 9.3 0.5 1.5 2.9 0.9 11.4 22.4 3.2 0.6 3.8 2.7 2.2 4.4 0.9 1.2 24.9 275.1 4.2 4.6 1.4 0.9 2.4 5.9 2.5 2.9 2.2 1.2 3.7 3.6 0.6 3.1 1.0 3.6 1.9 21.7 1.6 0.4 8.9 8.5 2.3 1.2 2.3 4.1 1.0 3.2 3.3 2.5 1.2 2.9 5.8 3.4 1.2 15.7 2.4 1.8 2.4 2.6 4.6 3.9 12.1 2.4 6.7 1.6 2.7 3.7 1.6 1.7 7.8 0.8 2.0 1.8 9.3 7.5 16.2 1.7 2.8 5.0 2.4 3.5 7.6 3.2 2.1 10.2 5.2 2.4 4.5 3.6 1.9 5.9 2.7 1.5 14.2 4.2 1.9 2.5 11.1 5.8 3.9 1.9 1.9 2.6 1.4 3.0 1.0 3.2 1.7 3.8 3.5 4.1 2.4 6.1 5.1 3.9 5.4 2.7 4.9 2.2 2.2 5.2 6.6 5.6 2.8 2.6 4.4 4.2 4.9 5.6 2.6 3.3 4.3 4.4 3.6 3.5 3.4 6.6 3.7 1.0 0.9 0.5 1.5 0.9 1.2 1.4 0.9 1.2 0.4 1.2 1.2 5.4 6.4 3.2 0.7 8.2 0.4 3.2 4.1 1.8 1.6 2.1 1.4 1.6 18.6 3.0 9.2 0.0 7.9 9.2 18.4 19.6 5.4 0.3 4.4 2.7 8.3 23.4 26.5 0.6 6.2 5.3 2.9 27.0 8.6 1.3 3.4 14.6 183.0 13.2 0.0 0.4 15.8 2.0 16.6 2.4 0.0 1.2 9.1 3.6 1.0 7.7 1.2 9.2 0.5 0.7 4.0 40.6 0.0 13.5 2.8 105.2 83.0 2.4 1.5 0.0 2.7 2.7 1.8 8.3 2.1 1.3 11.1 9.3 7.7 24.9 4.3 GMFG ENSG00000130755 "Glia maturation factor gamma" O60234 19 39328353-39342372 "Plasma proteins, Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 577.4;lymphoid tissue: 460.7" "Cell type enhanced" "Detected in many" "Adipocytes: 304.3;Hofbauer cells: 467.5;Kupffer cells: 523.4;Langerhans cells: 343.2;Macrophages: 409.6;monocytes: 409.4;NK-cells: 423.3;T-cells: 370.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 356.7;HMC-1: 602.6;JURKAT: 464.5;Karpas-707: 494.4;NB-4: 361.6;REH: 409.8;THP-1: 641.5;U-937: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002954 Uncertain Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA002954: AB_1078997" "unprognostic (1.22e-2)" "prognostic favorable (7.35e-4)" "unprognostic (2.37e-2)" "unprognostic (1.21e-3)" "unprognostic (9.93e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-1)" "unprognostic (4.84e-2)" "unprognostic (1.00e-1)" "unprognostic (2.09e-1)" "unprognostic (3.09e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.11e-6)" "unprognostic (3.01e-1)" "unprognostic (8.76e-3)" "unprognostic (1.06e-1)" "unprognostic (5.27e-3)" 111.6 26.3 27.1 188.6 27.4 577.4 71.3 26.9 41.6 26.0 29.3 45.6 33.8 20.7 19.6 19.7 29.0 60.8 25.1 27.9 29.1 36.8 65.9 117.7 299.5 30.7 30.1 9.2 14.4 15.6 10.8 102.4 30.5 18.5 53.2 2.0 18.9 15.0 11.4 16.2 75.0 47.8 29.1 325.3 41.5 7.4 28.6 460.7 37.6 23.6 262.7 93.5 18.3 32.6 1.4 0.0 2.0 0.4 0.0 0.0 0.7 1.1 0.3 0.3 0.2 0.3 33.1 309.6 2.4 0.3 0.1 1.5 0.0 0.7 1.2 99.7 0.5 329.7 0.4 3.5 5.1 356.7 602.6 0.7 0.6 0.5 0.8 0.8 19.2 464.5 12.3 494.4 2.4 0.0 316.6 361.6 0.6 0.1 0.2 409.8 3.2 196.8 0.5 40.9 0.8 0.5 1.3 1.9 2.1 0.6 0.8 641.5 175.7 0.2 3.2 0.8 1.1 26.9 107.3 340.0 1.7 482.4 2.7 4389.0 1574.5 3622.3 720.9 1447.6 773.8 812.5 1058.2 894.4 1139.9 742.7 1044.5 858.2 5262.9 908.0 1686.2 459.6 1840.4 2617.7 27.1 27.4 26.9 41.6 27.9 29.1 30.7 30.1 30.5 29.1 28.6 32.6 304.3 28.9 97.6 0.0 211.7 18.6 4.4 0.3 2.8 0.0 4.2 9.4 3.2 11.5 17.3 0.0 0.0 3.6 273.5 0.9 0.0 1.1 11.8 0.6 2.2 176.4 0.0 119.4 0.5 0.7 4.0 18.2 9.7 0.8 238.0 0.3 272.4 11.8 467.5 0.0 0.4 0.3 2.0 523.4 343.2 30.4 1.8 409.6 74.7 1.9 409.4 0.7 423.3 0.5 0.3 0.3 0.0 0.4 216.8 1.1 0.3 4.6 8.9 0.3 46.0 4.2 26.4 8.6 3.3 1.4 14.8 5.5 370.6 2.3 1.1 4.1 GMNN Gem ENSG00000112312 "Geminin DNA replication inhibitor" O75496 6 24774931-24786099 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "DNA replication inhibitor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 231.4" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 184.8;Paneth cells: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011458, CAB047327, CAB047328, HPA049977, HPA054597" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 25: Pancreas - Digestion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB011458: AB_2110946, CAB047327: , CAB047328: , HPA049977: AB_2680978, HPA054597: AB_2682538" "unprognostic (1.37e-1)" "unprognostic (3.43e-3)" "unprognostic (3.91e-3)" "unprognostic (1.52e-2)" "unprognostic (1.28e-1)" "unprognostic (4.37e-2)" "unprognostic (2.90e-3)" "unprognostic (8.29e-2)" "unprognostic (1.23e-3)" "prognostic favorable (4.13e-4)" "prognostic unfavorable (9.77e-4)" "unprognostic (1.33e-2)" "prognostic unfavorable (7.82e-5)" "unprognostic (2.25e-1)" "unprognostic (7.92e-2)" "unprognostic (3.63e-2)" "unprognostic (5.90e-3)" 10.1 7.7 16.9 17.2 18.2 68.9 24.2 19.5 23.7 11.1 13.5 41.6 17.8 10.6 5.8 16.6 16.5 7.9 8.0 14.7 20.2 24.6 18.2 8.9 30.4 17.0 20.2 14.6 231.4 8.4 11.1 16.5 17.8 41.5 44.4 16.3 8.7 24.9 7.4 40.3 16.1 12.5 16.4 19.1 22.6 37.4 19.8 37.4 10.8 14.3 23.7 28.4 13.9 15.5 110.9 64.2 159.2 66.2 22.2 23.5 106.0 106.0 55.9 124.4 135.5 125.1 38.8 110.1 131.3 34.4 91.3 63.3 139.4 78.1 133.0 41.2 145.4 151.5 109.3 207.4 20.7 119.1 53.1 19.1 25.1 75.9 29.5 25.8 62.2 84.6 193.9 56.9 88.9 86.3 224.9 128.2 87.3 89.6 50.2 128.9 124.4 141.2 53.5 94.6 127.3 78.3 47.5 77.4 95.2 89.1 81.3 72.0 30.9 75.7 76.8 88.3 182.6 62.8 207.6 210.3 23.1 220.9 111.2 5.5 5.2 17.1 4.4 6.9 5.6 9.2 8.5 6.9 7.6 4.6 6.1 6.9 3.0 5.9 5.0 9.4 15.9 5.6 16.9 18.2 19.5 23.7 14.7 20.2 17.0 20.2 17.8 16.4 19.8 15.5 24.0 6.4 15.6 8.8 17.0 33.0 28.4 57.4 18.8 9.5 51.0 52.5 12.1 18.6 68.1 44.1 2.1 83.2 19.9 72.6 9.8 113.6 94.8 84.8 30.6 18.4 25.9 66.2 3.5 112.3 136.3 17.7 12.2 184.8 13.3 36.4 13.9 17.4 54.0 11.8 5.3 66.3 10.2 10.7 13.2 28.0 9.6 15.2 23.2 5.6 12.6 30.9 6.2 5.5 3.2 31.8 300.5 10.9 41.6 25.6 20.8 20.6 25.2 13.7 19.7 8.0 21.9 158.8 58.8 26.8 63.5 48.7 19.1 30.4 156.5 30.1 GNAI2 "GIP, GNAI2B" ENSG00000114353 "G protein subunit alpha i2" P04899 3 50226292-50259362 "Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 656.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007704 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 4000000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "Nucleoplasm, Plasma membrane" "HPA007704: AB_1849230" "prognostic favorable (1.03e-4)" "unprognostic (3.89e-1)" "unprognostic (3.35e-2)" "unprognostic (8.40e-3)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (2.59e-2)" "unprognostic (3.23e-1)" "unprognostic (1.08e-3)" "unprognostic (6.01e-2)" "unprognostic (7.00e-3)" "unprognostic (1.12e-1)" "unprognostic (6.24e-3)" "unprognostic (1.44e-1)" "unprognostic (4.30e-2)" "unprognostic (4.33e-2)" "unprognostic (1.38e-1)" 210.2 100.3 155.2 217.9 167.3 367.1 152.8 166.3 181.6 146.0 120.2 142.1 69.9 141.7 66.9 124.4 136.9 152.5 157.1 144.3 184.6 79.4 126.5 214.5 251.3 199.8 170.2 147.7 64.1 66.9 99.2 241.8 194.8 103.6 64.3 35.6 71.9 156.9 69.3 87.0 103.0 154.0 173.6 262.1 73.6 69.6 173.3 160.3 101.3 89.4 170.4 169.7 108.4 193.2 128.2 63.0 186.3 197.6 220.7 277.5 35.5 271.1 399.6 354.9 361.1 70.4 173.2 149.1 119.2 567.0 193.4 100.1 132.8 350.3 222.8 331.2 50.9 364.8 158.0 110.2 219.8 329.2 479.8 270.3 152.9 319.1 129.8 289.6 837.8 124.1 26.1 307.1 357.5 155.7 313.6 433.0 109.7 59.0 302.4 185.0 89.8 219.7 232.6 130.9 48.4 86.1 189.5 57.1 124.4 150.4 94.3 346.1 792.3 330.9 187.5 309.2 274.7 199.4 278.3 127.0 373.6 466.9 398.1 16.6 59.3 113.7 33.7 80.9 20.2 28.8 26.8 34.3 57.3 26.1 20.2 25.8 145.2 23.5 74.5 47.2 34.0 27.3 155.2 167.3 166.3 181.6 144.3 184.6 199.8 170.2 194.8 173.6 173.3 193.2 656.8 41.7 32.1 25.1 119.5 56.7 59.7 32.3 45.5 29.0 61.6 83.8 22.9 55.8 26.6 44.1 14.6 79.5 311.4 11.7 5.9 124.3 203.3 57.8 115.7 340.3 92.2 52.1 12.4 60.5 84.4 101.9 21.9 71.8 89.9 150.0 221.3 79.7 336.0 6.7 14.8 24.6 18.3 342.7 291.7 302.0 90.7 386.1 83.6 58.1 356.6 292.6 151.4 26.7 45.4 160.3 40.9 95.5 104.8 46.1 30.3 24.5 24.4 21.9 52.6 85.3 163.1 16.6 22.6 37.6 62.9 116.4 164.9 156.3 20.5 70.1 GNAZ ENSG00000128266 "G protein subunit alpha z" P19086 22 23070519-23125032 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.2" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Horizontal cells: 124.5;Rod photoreceptor cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 18.3;SCLC-21H: 39.0;SH-SY5Y: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003011 Enhanced Approved Vesicles NA NA 180000 "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA003011: AB_1078918" "unprognostic (7.61e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (3.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-3)" "unprognostic (1.68e-2)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (6.63e-2)" "unprognostic (2.82e-1)" "unprognostic (1.30e-1)" 9.2 6.6 30.7 2.8 35.9 1.6 8.4 27.4 36.2 5.4 27.8 14.8 1.7 10.1 2.8 5.0 10.2 11.2 2.4 33.6 24.5 2.0 0.5 1.4 1.8 29.6 30.7 8.9 1.6 7.5 24.1 0.3 32.0 8.5 1.6 33.0 1.8 17.2 1.4 1.4 3.2 11.9 27.0 4.7 11.5 4.3 29.0 0.5 1.5 2.1 1.2 8.0 3.6 35.7 0.1 2.0 6.8 14.3 0.0 0.0 0.4 9.2 18.3 8.9 6.0 0.1 0.1 17.7 0.6 0.8 12.2 0.3 8.4 0.3 6.4 2.2 7.0 1.1 10.2 13.1 0.6 0.0 1.4 0.0 0.3 0.2 0.5 2.2 0.2 1.0 0.2 5.4 0.2 6.4 0.1 0.1 4.1 0.5 5.5 0.1 6.8 2.7 0.1 0.1 39.0 24.0 2.0 4.4 1.9 0.8 1.9 0.2 0.0 7.2 8.2 2.0 0.2 6.6 12.0 9.2 3.7 0.6 2.8 0.9 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.0 2.0 30.7 35.9 27.4 36.2 33.6 24.5 29.6 30.7 32.0 27.0 29.0 35.7 32.1 3.2 0.0 4.9 0.7 0.3 0.3 0.4 0.0 12.6 0.8 1.7 1.6 7.2 0.7 3.7 8.4 0.0 0.7 0.3 0.0 2.0 1.5 1.6 0.5 5.0 4.8 2.7 11.0 1.6 0.0 1.1 1.5 0.4 0.0 2.1 2.2 0.4 0.1 124.5 11.0 0.3 2.0 0.0 1.7 2.1 4.1 18.6 1.8 1.0 1.2 19.3 1.0 2.0 16.5 0.7 0.0 4.1 0.1 0.3 0.1 0.9 1.3 37.7 0.0 9.0 2.1 2.0 4.2 0.0 0.4 0.0 0.6 0.9 0.2 0.1 GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 1903.6;Endothelial cells: 1236.2;Hepatic stellate cells: 994.2;Macrophages: 481.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cell line enhanced" "Detected in many" "EFO-21: 219.9;HUVEC TERT2: 349.6;SK-MEL-30: 221.8;TIME: 201.1;U-87 MG: 187.1" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 3400000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA045255: AB_10794781" "unprognostic (1.30e-1)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (4.89e-3)" "unprognostic (4.94e-2)" "unprognostic (2.63e-2)" "unprognostic (2.58e-2)" "unprognostic (3.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.14e-3)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (4.71e-3)" 75.5 16.8 14.4 8.1 14.6 2.5 64.4 14.7 22.0 24.9 13.7 23.5 6.7 26.8 10.9 10.9 33.5 15.5 48.3 14.1 14.7 34.9 12.1 39.8 7.8 14.9 14.6 56.7 8.8 4.4 9.3 85.9 15.3 15.8 6.4 1.5 9.1 17.9 15.4 11.4 16.1 16.7 15.1 39.0 16.0 3.3 16.1 19.0 29.1 18.6 3.5 27.9 18.4 14.9 0.2 34.2 67.2 31.0 51.2 40.0 0.0 34.8 67.7 19.0 26.7 0.1 2.9 0.0 219.9 17.5 79.9 0.5 0.5 3.2 23.8 0.2 2.0 11.0 35.9 0.0 81.8 0.0 0.1 13.4 0.1 61.0 6.0 78.7 349.6 0.0 0.1 0.2 85.9 0.0 0.1 0.1 5.8 0.0 10.4 32.5 7.6 0.1 41.3 0.0 0.1 67.2 0.0 0.2 221.8 8.6 144.4 2.4 201.1 93.4 10.4 68.3 3.9 0.0 0.2 0.7 187.1 0.0 81.8 20.5 0.7 0.3 0.1 0.1 0.2 2.3 0.0 0.0 1.0 2.0 0.2 0.0 9.8 0.0 0.1 3.7 0.1 50.2 14.4 14.6 14.7 22.0 14.1 14.7 14.9 14.6 15.3 15.1 16.1 14.9 1903.6 12.8 27.3 1.3 20.6 83.6 11.8 3.1 5.7 0.7 15.2 26.8 94.8 11.5 3.1 187.6 0.0 2.3 15.4 0.1 74.3 135.7 5.9 124.1 94.6 1236.2 0.0 40.6 0.0 5.7 12.9 207.3 0.5 236.4 2.5 12.7 994.2 11.1 17.0 0.0 0.0 0.3 18.3 55.9 89.5 17.0 82.3 481.1 188.5 26.2 49.6 9.2 41.2 0.5 0.2 4.3 0.0 86.9 8.0 11.0 0.0 12.9 1.7 4.7 151.2 115.5 165.0 1.9 7.6 2.7 65.8 23.8 15.9 109.9 0.0 4.5 GNG2 ENSG00000186469 "G protein subunit gamma 2" P59768 14 51826195-51979342 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 113.4" "Cell type enhanced" "Detected in many" "dendritic cells: 251.8;Early spermatids: 714.4;Late spermatids: 1146.4;NK-cells: 246.1" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 77.2;fHDF/TERT166: 140.2;MOLT-4: 112.5;SH-SY5Y: 89.2;WM-115: 249.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003534, CAB018380" Uncertain Supported Approved "Vesicles,Plasma membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Vesicles "CAB018380: AB_631547, HPA003534: AB_1079004" "unprognostic (6.11e-2)" "unprognostic (5.78e-3)" "unprognostic (2.06e-3)" "unprognostic (6.55e-2)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (5.72e-2)" "unprognostic (1.24e-1)" "prognostic favorable (1.64e-4)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.90e-6)" "unprognostic (9.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (3.59e-2)" 51.3 22.0 38.5 41.1 44.8 64.0 21.0 0.8 55.4 11.9 10.9 24.1 15.2 12.2 5.1 14.1 5.8 17.3 13.5 54.1 75.2 7.5 12.7 19.0 47.7 10.6 20.5 14.4 7.3 3.5 14.9 19.5 27.2 10.6 19.6 15.0 8.1 9.0 5.6 7.8 21.2 19.8 13.6 61.7 15.9 113.4 46.4 62.0 5.7 13.1 45.4 22.2 5.3 22.2 0.0 3.1 77.2 48.6 11.6 15.0 1.2 12.9 15.9 6.1 4.9 6.4 0.2 0.2 1.8 140.2 8.9 0.3 10.4 0.0 4.2 36.4 1.2 0.0 0.7 0.0 6.0 7.4 0.3 25.1 0.0 6.2 0.5 32.2 0.0 67.9 0.0 6.5 39.7 0.0 112.5 12.0 41.1 0.0 9.5 39.4 6.1 2.0 6.4 0.0 11.5 89.2 0.3 0.1 34.5 2.7 0.0 0.3 0.0 18.7 3.1 0.3 9.9 0.2 0.0 5.5 15.5 39.2 249.0 379.4 64.0 177.1 162.8 111.9 110.5 38.1 88.9 134.2 65.8 36.2 55.5 98.5 185.2 25.2 177.3 28.0 143.2 158.6 38.5 44.8 0.8 55.4 54.1 75.2 10.6 20.5 27.2 13.6 46.4 22.2 11.6 6.4 7.2 3.3 101.3 11.5 0.4 0.0 2.2 18.7 1.5 1.9 1.0 1.5 0.0 3.7 2.1 0.6 251.8 0.8 1.9 0.2 714.4 0.5 2.7 11.7 175.8 20.4 66.2 0.0 0.6 23.9 11.7 0.8 32.3 0.2 11.0 0.9 51.1 0.0 59.6 2.4 0.0 94.1 60.0 1146.4 9.9 84.0 55.2 24.4 33.3 0.7 246.1 96.0 3.2 0.5 0.1 6.0 62.7 0.2 0.1 0.9 0.0 2.2 39.5 10.2 12.2 11.2 4.6 1.3 6.7 0.7 191.5 2.2 0.5 0.2 GNMT ENSG00000124713 "Glycine N-methyltransferase" Q14749 6 42960754-42963880 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "liver: 296.5;pancreas: 600.1" "Cell type enriched" "Detected in many" 10 "Hepatocytes: 842.9" "Group enriched" "Detected in many" 20 "liver cancer: 69.6;prostate cancer: 49.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 8.5;SCLC-21H: 9.5;T-47d: 6.1" "Region enriched" "Detected in some" 4 "cerebellum: 15.7" "Low region specificity" "Detected in many" HPA027501 Enhanced Approved Cytosol NA NA 390000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA027501: AB_1849879" "unprognostic (1.53e-2)" "unprognostic (8.02e-4)" "unprognostic (3.11e-2)" "unprognostic (4.24e-3)" "unprognostic (3.91e-2)" "unprognostic (6.40e-4)" "prognostic favorable (1.86e-4)" "unprognostic (4.08e-6)" "unprognostic (1.01e-1)" "unprognostic (2.67e-2)" "unprognostic (1.63e-3)" "unprognostic (2.52e-1)" "unprognostic (3.50e-3)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (2.49e-2)" "unprognostic (4.92e-2)" 0.9 0.9 2.3 1.3 2.5 3.8 7.1 2.8 2.4 0.8 2.0 0.7 0.2 0.8 2.2 0.6 1.3 0.5 4.7 2.2 2.2 0.9 296.5 2.0 1.0 1.1 1.0 1.9 600.1 0.2 8.4 0.4 1.1 20.3 0.3 2.2 9.8 1.2 1.8 0.9 1.6 0.5 0.9 2.9 50.8 0.7 1.9 1.8 1.9 0.4 1.2 0.8 0.7 2.1 0.4 0.3 1.4 3.9 0.4 0.1 0.2 0.3 1.6 0.6 0.9 0.0 0.1 1.3 0.1 0.3 0.7 0.4 0.2 0.2 0.2 1.6 1.2 1.0 0.9 8.5 0.0 0.9 1.8 0.3 0.0 0.3 0.1 0.9 0.0 3.0 1.2 1.5 0.2 1.8 1.6 3.0 0.1 0.4 0.4 1.4 1.3 0.8 0.6 0.2 9.5 1.3 0.1 1.3 0.6 0.4 6.1 2.8 0.3 0.7 0.7 0.4 0.8 1.0 1.0 1.1 0.1 1.6 0.8 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.5 0.0 0.0 0.7 0.0 0.1 2.3 2.5 2.8 2.4 2.2 2.2 1.1 1.0 1.1 0.9 1.9 2.1 0.3 0.0 2.2 5.5 2.8 0.3 5.2 0.7 0.0 1.7 10.2 14.7 5.4 24.3 0.2 1.8 0.0 0.1 1.7 0.0 3.9 0.5 0.2 1.6 0.2 2.2 0.0 77.9 18.4 0.9 0.1 0.3 0.5 0.8 0.0 2.6 24.3 842.9 0.7 1.7 18.2 0.0 6.1 28.9 0.7 0.1 0.9 1.1 0.0 11.2 0.3 0.2 0.0 7.1 4.7 0.6 0.0 2.6 0.5 17.9 0.3 3.4 4.6 0.3 0.0 0.2 0.6 0.6 0.7 0.0 0.1 0.1 3.0 0.0 0.2 1.9 GNPTG "C16orf27, c316G12.3, CAB56184, GNPTAG" ENSG00000090581 "N-acetylglucosamine-1-phosphate transferase subunit gamma" Q9UJJ9 16 1351931-1364113 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 135.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004055 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 560000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" Cytosol "HPA004055: AB_1079006" "unprognostic (4.37e-2)" "unprognostic (2.20e-2)" "unprognostic (1.84e-1)" "unprognostic (9.57e-3)" "unprognostic (2.70e-3)" "unprognostic (2.09e-1)" "unprognostic (3.03e-2)" "unprognostic (3.66e-1)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.14e-2)" "unprognostic (2.20e-1)" "unprognostic (2.31e-1)" "unprognostic (4.85e-2)" "unprognostic (2.07e-2)" 34.8 94.0 33.5 19.3 41.3 25.0 34.5 37.8 43.3 31.4 43.2 27.9 17.7 29.7 28.9 23.6 28.5 23.7 28.7 32.6 34.8 37.1 40.9 28.4 27.9 38.8 35.5 35.7 39.6 40.2 32.9 20.9 39.3 29.9 16.2 15.6 42.9 20.7 34.6 37.2 30.9 14.9 35.1 38.3 34.8 21.4 35.7 13.3 33.9 16.9 14.4 28.8 26.5 44.5 13.3 21.2 15.3 26.9 135.2 50.3 20.1 38.3 49.6 14.9 28.4 19.1 37.0 8.4 43.0 51.8 22.5 24.0 9.2 22.4 7.6 27.0 20.2 11.3 73.9 33.0 57.6 18.2 43.2 67.3 38.4 14.2 20.3 41.6 27.5 15.2 13.7 48.4 24.6 30.7 8.7 18.7 14.4 33.9 11.8 30.5 12.9 38.6 37.3 17.1 12.0 15.5 38.5 39.2 28.7 8.5 36.9 27.3 27.0 29.8 25.5 24.6 19.1 50.6 40.4 17.7 24.4 15.6 20.3 70.5 77.0 49.5 43.3 74.4 39.6 32.1 36.7 40.8 61.5 31.1 33.4 30.8 32.0 32.6 73.9 52.2 46.9 49.7 33.5 41.3 37.8 43.3 32.6 34.8 38.8 35.5 39.3 35.1 35.7 44.5 39.7 41.7 41.7 17.3 31.9 20.9 26.5 25.4 46.7 15.1 34.0 42.9 9.4 37.1 43.2 20.2 25.0 25.0 34.9 25.8 9.8 27.4 2.6 17.7 29.8 25.6 9.1 9.9 22.7 14.5 20.3 49.7 47.4 23.7 24.6 21.1 30.7 35.2 50.2 8.4 20.5 18.0 14.2 43.4 41.7 4.6 30.1 47.8 33.8 9.4 25.7 31.0 30.9 15.1 32.4 14.8 32.9 17.7 76.1 22.1 32.1 41.7 28.5 24.5 19.7 24.4 22.9 25.4 24.2 48.1 20.3 31.1 30.6 20.5 21.7 24.5 GOLT1A "CGI-141, FLJ42654, GOT1, MGC62027, YMR292W" ENSG00000174567 "Golgi transport 1A" Q6ZVE7 1 204198163-204213988 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 190.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 131.3;Proximal enterocytes: 206.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 80.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 18.0;CAPAN-2: 20.0;Hep G2: 25.9;MCF7: 43.5;OE19: 16.1;RT4: 27.7;SK-BR-3: 27.2" "Region enhanced" "Detected in many" "cerebral cortex: 9.0" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.43e-1)" "unprognostic (1.13e-1)" "unprognostic (2.22e-3)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (6.20e-3)" "unprognostic (2.14e-1)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.26e-2)" "unprognostic (7.33e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.35e-5)" "unprognostic (1.37e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-3)" "prognostic favorable (1.51e-4)" 0.3 0.1 6.1 0.4 9.2 0.0 5.3 7.0 5.3 10.9 3.9 5.6 47.4 0.3 10.7 0.5 3.3 1.6 0.1 4.3 11.2 16.2 190.7 8.3 0.1 4.7 5.3 0.1 22.3 18.3 30.4 3.5 4.7 5.3 5.0 1.5 3.4 2.1 0.3 0.5 45.5 0.3 4.5 0.1 8.2 2.6 11.6 0.8 0.7 0.0 0.2 13.1 0.4 2.8 0.5 8.2 0.0 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 18.0 20.0 0.0 0.7 0.2 0.0 0.6 0.0 0.1 0.1 0.0 0.3 0.1 0.0 25.9 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 43.5 0.0 0.1 4.0 16.1 0.2 0.0 0.1 0.4 8.5 27.7 1.3 1.8 0.8 27.2 0.1 0.7 8.9 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 6.1 9.2 7.0 5.3 4.3 11.2 4.7 5.3 4.7 4.5 11.6 2.8 0.1 0.0 19.5 0.3 0.1 0.0 12.7 2.6 2.8 1.7 7.2 4.7 0.2 40.0 5.1 16.5 0.0 13.3 0.1 7.0 13.7 29.2 0.9 0.5 0.1 0.3 10.3 0.0 2.2 19.1 0.5 1.1 8.2 2.0 1.3 1.4 1.8 131.3 1.3 1.7 0.7 7.8 2.0 1.6 0.0 0.4 0.0 0.2 1.8 0.0 0.0 0.0 0.0 4.5 0.1 18.7 5.6 0.0 0.0 15.0 206.8 14.7 0.3 0.2 0.0 0.3 0.3 2.9 0.9 1.4 0.1 26.4 0.5 0.2 12.5 20.5 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA016471: AB_1844649" "unprognostic (3.05e-2)" "unprognostic (4.05e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (7.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (5.11e-2)" "unprognostic (3.79e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.98e-2)" "prognostic favorable (4.15e-4)" "unprognostic (1.73e-3)" "unprognostic (3.16e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" "prognostic favorable (5.65e-4)" 23.6 33.6 13.5 28.0 15.3 28.4 42.4 29.7 17.6 24.7 25.0 21.3 19.7 28.6 12.8 16.3 21.0 23.1 20.4 13.4 15.0 30.1 32.7 23.9 22.3 16.2 16.5 23.0 23.1 40.5 16.2 27.2 15.6 18.3 21.7 15.4 25.4 20.3 57.6 18.4 19.0 33.2 15.4 21.2 26.8 24.2 15.7 22.1 20.0 39.9 27.4 24.6 18.8 16.8 39.0 42.4 49.7 38.9 53.1 64.1 43.7 82.7 70.8 61.4 63.6 28.7 76.1 53.8 56.6 68.7 75.4 22.0 58.7 37.3 78.8 58.0 32.4 63.0 49.0 26.5 31.0 6.8 87.1 40.6 26.9 64.0 23.0 52.5 64.1 52.7 47.9 61.5 63.4 16.5 60.0 17.3 53.1 71.3 22.5 34.7 49.8 29.2 36.4 57.5 32.4 44.7 32.2 43.9 89.1 56.5 60.9 42.4 47.0 63.0 43.8 73.0 62.6 33.0 47.9 58.7 51.9 36.9 63.1 16.0 17.0 7.8 12.5 15.9 11.6 8.6 9.6 12.6 21.0 9.9 8.5 8.5 3.8 5.8 14.3 8.0 9.7 13.8 13.5 15.3 29.7 17.6 13.4 15.0 16.2 16.5 15.6 15.4 15.7 16.8 20.0 3.2 31.2 0.0 14.5 0.0 13.2 0.0 11.4 16.9 50.2 19.6 0.0 27.1 13.6 11.0 10.4 33.9 18.4 10.8 3.9 41.3 40.6 14.1 19.4 21.7 17.0 21.5 0.0 39.8 42.5 13.1 27.0 29.2 2.5 21.2 18.2 62.4 27.1 15.2 0.0 14.2 0.0 28.1 0.0 58.7 12.8 31.7 0.0 0.0 31.2 11.8 9.2 0.0 0.0 44.9 11.3 10.5 23.9 27.7 13.3 28.2 5.8 15.1 6.6 20.3 11.6 4.3 14.8 10.1 0.0 40.4 16.7 23.0 11.1 18.2 GPATCH11 "CCDC75, CENP-Y, CENPY, FLJ38348" ENSG00000152133 "G-patch domain containing 11" Q8N954 2 37084451-37099244 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038231, HPA038232" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA038231: AB_2675904, HPA038232: AB_10675788" "unprognostic (1.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.45e-1)" "unprognostic (1.80e-1)" "unprognostic (3.88e-2)" "unprognostic (2.23e-2)" "unprognostic (4.58e-3)" "unprognostic (2.40e-2)" "unprognostic (2.44e-2)" "unprognostic (4.39e-2)" "unprognostic (1.16e-1)" "unprognostic (1.26e-1)" "unprognostic (8.64e-3)" "unprognostic (4.31e-2)" "unprognostic (4.44e-2)" "unprognostic (3.40e-2)" "unprognostic (7.16e-2)" 23.0 6.3 7.5 7.8 8.5 10.0 6.9 8.8 9.9 7.0 6.0 4.5 4.8 4.8 3.7 5.1 3.7 4.4 5.4 7.7 8.8 5.5 5.7 6.3 12.7 8.3 8.0 5.9 3.0 5.5 3.5 5.7 8.5 4.0 4.9 21.0 3.7 4.1 2.4 5.9 5.0 4.3 8.5 8.0 4.8 11.6 8.0 10.3 6.4 5.4 11.7 5.2 3.1 10.4 12.5 7.4 12.4 9.7 25.7 11.9 13.2 22.1 8.9 13.1 10.7 9.4 5.2 14.4 12.1 8.3 11.4 8.8 14.8 5.3 19.5 24.7 16.1 26.3 9.8 9.6 8.3 31.7 27.5 7.8 9.4 18.0 10.1 8.6 11.6 9.0 25.0 65.8 15.4 6.3 20.6 17.4 5.3 20.5 10.3 16.9 26.4 40.7 5.7 5.3 14.9 13.9 11.6 7.4 11.2 9.9 7.6 14.6 12.9 23.7 13.1 17.4 24.7 25.6 28.2 21.6 16.9 26.2 21.3 5.9 2.4 2.2 4.4 2.0 4.4 8.7 3.2 3.7 3.6 6.8 3.4 3.5 0.8 6.7 0.7 12.2 2.6 1.5 7.5 8.5 8.8 9.9 7.7 8.8 8.3 8.0 8.5 8.5 8.0 10.4 14.7 12.8 8.1 3.9 23.3 4.2 2.7 5.7 7.4 24.3 6.2 7.0 14.1 8.6 5.0 11.0 25.0 8.8 48.7 12.1 11.7 9.3 32.9 12.6 20.0 12.8 3.0 22.1 14.3 14.1 30.5 12.2 8.6 13.9 12.0 8.7 17.9 15.0 13.4 13.5 12.1 9.1 6.1 18.8 15.0 10.5 16.1 21.1 3.6 5.6 12.7 28.9 22.6 10.6 12.5 14.8 4.9 22.2 23.2 1.6 9.7 13.2 11.5 52.7 13.1 13.4 21.7 75.5 43.6 7.8 5.4 3.8 16.8 13.7 6.0 2.0 GPBAR1 "BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5" ENSG00000179921 "G protein-coupled bile acid receptor 1" Q8TDU6 2 218259496-218263861 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.9;breast: 17.8;gallbladder: 17.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 20.3;Enteroendocrine cells: 46.0;Hofbauer cells: 16.3;Kupffer cells: 50.6;Macrophages: 19.9;monocytes: 45.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "classical monocyte: 288.1;intermediate monocyte: 712.0;non-classical monocyte: 695.6" "Lineage enriched" "Detected in many" 5 "monocytes: 712.0" "Cell line enhanced" "Detected in some" "ASC diff: 1.1;HHSteC: 1.7;U-937: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA062890 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA062890: AB_2684896" "unprognostic (8.47e-2)" "unprognostic (3.72e-3)" "unprognostic (1.88e-2)" "unprognostic (9.49e-2)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-1)" "unprognostic (2.63e-1)" "unprognostic (8.76e-3)" "unprognostic (4.32e-2)" "unprognostic (4.64e-2)" "unprognostic (1.55e-1)" "unprognostic (7.40e-7)" "unprognostic (4.18e-2)" "unprognostic (4.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" 31.9 1.6 0.1 2.7 0.2 2.2 17.8 0.4 0.7 0.6 0.2 3.8 1.0 0.9 0.0 0.5 1.2 17.3 5.1 0.2 0.1 5.3 1.9 2.2 0.8 0.1 0.1 1.8 1.7 0.0 0.8 3.9 0.1 1.1 0.5 0.0 0.8 0.3 0.5 1.4 4.9 10.1 0.1 7.5 6.4 2.4 0.3 0.4 1.7 0.7 0.2 4.8 0.8 0.1 0.1 0.0 0.1 0.0 1.1 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 1.7 0.1 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.9 0.8 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 1.9 0.1 0.6 288.1 0.4 0.7 712.0 0.7 0.2 0.5 0.7 140.2 0.7 0.6 0.4 6.5 0.5 695.6 6.0 0.9 156.5 0.1 0.2 0.4 0.7 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 6.2 0.0 3.4 0.0 1.1 0.3 0.2 0.2 0.0 0.0 0.1 0.3 0.5 1.5 0.1 3.7 0.0 0.5 1.8 0.2 11.7 0.2 8.2 1.0 20.3 1.5 46.0 0.0 0.0 0.5 4.5 2.8 6.6 0.8 1.3 6.2 1.8 0.0 16.3 0.0 0.0 2.7 0.0 50.6 1.2 1.9 3.4 19.9 0.0 1.9 45.3 0.0 0.0 0.0 0.0 0.5 1.5 2.6 0.3 0.3 0.4 0.2 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.1 0.4 1.6 0.8 0.1 0.2 0.4 GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Excitatory neurons: 333.6;Inhibitory neurons: 496.1;Oligodendrocyte precursor cells: 691.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.5;HSkMC: 70.8;hTERT-RPE1: 64.3;SuSa: 39.5;U-87 MG: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA017671 Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" 9.1 2.2 0.8 8.9 1.9 0.1 2.2 1.7 1.5 3.6 1.1 6.3 2.3 2.4 2.4 5.2 4.1 17.0 6.2 1.3 3.1 7.7 17.7 3.5 0.4 1.7 2.4 7.3 1.6 1.8 2.9 1.3 2.3 6.2 6.5 5.6 3.1 15.1 0.6 1.1 4.3 7.8 2.0 2.2 5.4 2.0 1.9 1.7 1.7 1.9 0.9 11.6 2.4 2.1 0.0 4.7 10.2 4.5 62.5 19.5 0.0 7.2 0.0 4.9 6.4 0.0 0.0 0.2 0.0 16.0 0.0 0.0 5.7 1.2 9.1 0.0 4.1 0.0 0.1 20.2 37.8 0.1 0.1 70.8 0.5 11.7 8.1 64.3 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.1 6.4 0.0 3.4 0.0 1.6 0.1 5.5 0.0 4.1 16.8 0.0 1.9 0.0 39.5 14.0 0.0 0.0 26.9 22.6 25.4 12.3 15.9 0.1 0.0 52.8 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.9 1.7 1.5 1.3 3.1 1.7 2.4 2.3 2.0 1.9 2.1 0.6 0.0 0.5 163.2 0.0 0.6 0.5 0.5 0.6 50.3 0.6 1.9 1.7 4.3 0.7 7.3 10.4 0.2 0.0 0.1 0.0 0.3 6.7 1.6 25.9 1.1 0.0 0.0 333.6 0.0 0.1 31.2 0.0 3.1 0.0 36.0 5.7 41.2 0.5 0.0 496.1 0.1 2.0 1.3 1.0 5.0 4.7 0.5 1.8 31.9 0.0 2.7 0.0 691.6 13.2 0.1 0.0 1.9 0.1 1.6 0.0 14.5 0.0 115.0 0.0 34.4 20.9 4.2 2.7 0.5 0.4 0.1 0.7 11.9 0.1 0.2 GPD1 ENSG00000167588 "Glycerol-3-phosphate dehydrogenase 1" P21695 12 50103982-50111313 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 609.9;skeletal muscle: 577.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 99.1;Proximal enterocytes: 247.0;Proximal tubular cells: 298.4" "Cancer enhanced" "Detected in many" "liver cancer: 18.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 134.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044620, HPA058621" Enhanced NA NA 4700000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044620: AB_10796803, HPA058621: " "unprognostic (2.65e-2)" "unprognostic (5.60e-2)" "unprognostic (3.28e-2)" "unprognostic (3.37e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (1.45e-3)" "unprognostic (7.19e-2)" "unprognostic (9.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (1.37e-1)" "unprognostic (9.58e-2)" "unprognostic (3.37e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" 609.9 4.7 9.1 1.6 16.8 0.2 229.2 22.7 12.8 0.3 5.5 6.4 76.4 0.2 5.3 4.9 0.5 16.6 9.2 10.1 14.2 149.3 147.6 18.4 1.0 32.6 18.3 0.3 7.2 13.0 1.3 0.0 26.5 1.3 3.3 1.0 33.0 1.3 577.1 10.2 76.9 1.3 32.7 0.4 3.3 0.8 18.4 1.5 2.7 215.7 0.4 4.1 1.0 49.4 0.1 0.2 0.1 0.1 134.0 0.0 0.3 0.1 0.0 0.0 0.0 27.0 0.1 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.1 0.6 25.2 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.7 0.7 0.3 0.0 0.2 0.1 0.4 0.1 3.7 0.0 0.2 0.2 30.2 0.2 0.0 0.6 0.2 0.0 1.5 1.0 0.0 1.8 0.0 0.0 0.0 0.3 0.2 0.1 0.6 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 16.8 22.7 12.8 10.1 14.2 32.6 18.3 26.5 32.7 18.4 49.4 3.4 3.2 3.2 0.0 2.4 0.0 0.2 0.3 0.6 3.2 3.4 3.7 5.8 11.5 1.8 5.5 8.4 0.0 0.0 3.0 43.0 0.9 0.1 0.5 0.1 0.2 1.2 5.3 0.2 0.7 0.0 0.8 4.1 0.2 0.0 0.1 1.1 99.1 2.3 3.3 0.2 9.7 0.0 1.0 0.4 0.0 0.0 5.2 1.8 0.0 1.0 2.8 0.0 0.0 4.0 0.6 8.0 0.0 0.0 0.1 247.0 298.4 0.4 1.7 0.0 7.0 1.1 0.0 0.0 0.8 0.4 0.0 1.2 0.0 10.6 0.2 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 12.3;Granulosa cells: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.7;HHSteC: 133.9;hTCEpi: 61.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" 1.5 2.7 0.1 0.2 0.9 0.0 0.7 0.5 0.3 2.6 12.2 0.3 0.1 0.5 0.2 4.5 0.5 1.2 1.6 0.6 0.3 0.4 0.0 0.2 0.8 0.0 0.0 1.3 0.0 0.4 0.2 3.9 0.0 0.2 0.3 0.7 0.9 0.1 0.7 4.8 0.3 1.0 0.0 0.0 0.1 0.9 0.2 0.0 0.3 2.4 0.3 1.0 5.6 0.0 2.2 0.2 1.8 0.0 0.4 7.5 0.6 14.4 24.7 8.8 7.4 0.0 0.0 0.0 0.8 7.3 0.6 0.2 0.7 0.0 2.9 0.0 0.3 0.0 4.2 0.0 133.9 0.0 0.0 5.5 61.8 12.5 20.0 10.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 6.9 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 6.1 2.9 0.0 0.0 1.6 0.1 0.0 0.3 10.5 4.8 12.5 1.1 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 12.3 4.5 0.0 0.0 0.0 42.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.2 0.0 0.0 0.8 1.0 0.7 0.5 0.0 0.0 0.4 GPR12 "GPCR21, PPP1R84" ENSG00000132975 "G protein-coupled receptor 12" P47775 13 26755200-26760786 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;retina: 8.4;skin 1: 5.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 9.7;Excitatory neurons: 9.5;Hofbauer cells: 17.6;Horizontal cells: 33.7;Inhibitory neurons: 15.7;Skeletal myocytes: 8.1" "Group enriched" "Detected in some" 7 "breast cancer: 0.5;glioma: 0.8;ovarian cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050972 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA050972: AB_2681295" "unprognostic (2.37e-2)" "unprognostic (9.64e-3)" "unprognostic (3.75e-1)" "unprognostic (3.30e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-2)" "unprognostic (1.42e-1)" "unprognostic (7.35e-2)" "unprognostic (5.53e-2)" "unprognostic (3.83e-2)" "unprognostic (2.40e-1)" 0.2 0.0 3.7 0.0 14.3 0.1 1.4 7.6 10.7 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.2 8.1 1.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.7 0.4 0.2 0.0 0.0 8.4 2.9 0.0 0.1 5.4 0.1 0.1 0.1 0.1 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 14.3 7.6 10.7 8.1 1.0 0.0 3.3 0.2 0.1 4.3 2.9 0.4 0.0 0.0 1.6 0.0 0.1 0.2 0.0 0.0 2.8 2.7 2.8 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.7 9.7 0.0 9.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 17.6 33.7 15.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 3.6 0.0 0.0 1.9 0.0 5.0 0.9 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 3.5 0.0 8.1 0.2 0.1 0.3 0.0 0.1 0.3 0.2 0.0 0.0 0.2 GPR15 ENSG00000154165 "G protein-coupled receptor 15" P49685 3 98531978-98534681 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 31.3" "Cell type enriched" "Detected in some" 8 "Plasma cells: 31.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory B-cell: 3.6;memory CD4 T-cell: 10.8;memory CD8 T-cell: 5.1;T-reg: 12.1" "Group enriched" "Detected in many" 26 "B-cells: 3.6;T-cells: 12.1" "Group enriched" "Detected in some" 5 "HDLM-2: 4.6;U-266/70: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA013775 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA013775: AB_1849264" "unprognostic (8.03e-2)" "unprognostic (1.04e-2)" "unprognostic (3.72e-3)" "unprognostic (5.66e-2)" "unprognostic (9.48e-3)" "unprognostic (5.60e-5)" "unprognostic (5.17e-1)" "unprognostic (6.77e-3)" "unprognostic (3.96e-1)" "unprognostic (3.03e-2)" "unprognostic (2.82e-1)" "unprognostic (2.83e-1)" "unprognostic (4.04e-3)" "unprognostic (4.23e-3)" "unprognostic (1.89e-1)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" 0.6 0.0 0.0 4.5 0.2 0.2 3.8 0.1 0.2 0.5 0.0 20.0 2.7 0.2 0.0 2.5 0.1 2.3 0.1 0.0 0.1 0.2 0.3 1.9 2.4 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.4 31.3 0.0 4.9 0.2 0.0 0.3 10.2 0.8 0.1 5.3 1.6 0.0 0.1 1.9 0.4 0.0 5.3 7.2 1.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.3 3.6 10.8 5.1 0.0 0.6 0.5 0.8 0.3 0.0 0.0 0.2 12.1 2.1 0.0 0.2 0.1 0.2 0.0 0.1 0.5 0.3 0.4 0.1 0.1 0.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 GPR153 PGR1 ENSG00000158292 "G protein-coupled receptor 153" Q6NV75 1 6247353-6261098 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Hepatocytes: 33.2;Horizontal cells: 63.9;Intestinal goblet cells: 52.5;Urothelial cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.1;PC-3: 68.6;RH-30: 32.2;SCLC-21H: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007159 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA007159: AB_1849268" "unprognostic (1.02e-2)" "unprognostic (2.40e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (5.74e-3)" "unprognostic (3.33e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (8.54e-2)" "unprognostic (1.02e-2)" "unprognostic (1.31e-1)" "unprognostic (1.51e-2)" "unprognostic (1.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" 13.2 2.0 17.8 2.9 8.4 0.3 10.4 0.7 11.3 12.2 0.2 9.9 4.0 9.3 11.3 7.8 8.7 3.8 9.4 7.9 9.7 2.9 7.1 10.5 1.8 4.7 11.8 8.9 1.5 5.5 12.0 6.9 2.9 6.4 5.2 3.2 3.1 3.3 1.8 9.2 21.9 4.8 3.6 6.9 3.5 2.2 28.3 1.4 1.9 1.4 1.4 6.9 7.9 3.2 6.1 1.0 14.4 17.4 26.1 10.3 1.2 4.0 3.6 1.5 1.7 2.5 2.4 0.0 6.0 4.2 3.3 7.8 0.8 17.2 0.6 4.0 3.5 0.1 2.4 0.5 5.1 0.6 2.3 6.3 4.5 1.1 0.9 2.7 1.2 5.3 0.9 0.0 5.0 6.7 2.0 4.7 1.1 3.5 68.6 7.5 32.2 0.4 0.6 3.4 32.7 11.8 2.7 10.0 8.4 3.9 3.9 3.2 3.5 3.5 3.3 0.5 1.8 0.3 0.3 1.4 1.6 8.0 1.4 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 17.8 8.4 0.7 11.3 7.9 9.7 4.7 11.8 2.9 3.6 28.3 3.2 0.7 0.0 0.0 0.3 0.1 3.4 1.8 8.9 1.2 6.2 1.3 2.2 6.2 4.3 5.5 0.0 0.0 0.2 5.9 3.3 0.0 0.2 1.2 0.6 8.5 1.6 3.5 2.7 1.7 0.0 0.3 9.9 1.1 0.4 1.3 0.7 0.7 33.2 1.1 63.9 3.0 52.5 6.1 1.0 3.7 2.5 4.7 1.5 5.4 1.0 2.2 2.7 3.1 6.6 0.1 0.6 9.2 7.5 1.3 1.6 9.6 2.0 1.7 1.6 0.0 9.6 4.7 0.1 1.7 1.1 7.4 0.4 1.2 1.3 2.0 17.2 GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.9" "Cell type enhanced" "Detected in some" "B-cells: 6.6;dendritic cells: 30.6;Plasma cells: 4.2;T-cells: 18.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "JURKAT: 42.3;MOLT-4: 75.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041025, HPA058306" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" 0.8 0.4 0.5 6.9 0.3 2.5 0.9 0.6 0.6 0.4 0.3 1.0 2.0 0.5 0.6 0.3 0.3 1.1 0.3 0.4 0.4 0.5 1.0 1.9 15.2 0.7 0.5 0.2 0.1 0.1 0.1 0.2 0.7 0.7 1.6 0.2 1.5 0.1 0.2 0.2 3.6 0.3 0.3 8.1 2.1 0.1 0.4 16.9 0.9 0.1 10.4 1.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.2 0.0 0.0 75.1 0.1 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.2 0.0 0.0 0.0 6.5 0.0 3.6 3.6 2.0 1.2 2.5 4.8 6.1 0.1 2.6 4.2 4.9 0.3 4.6 5.5 1.0 4.8 1.6 0.5 0.3 0.6 0.6 0.4 0.4 0.7 0.5 0.7 0.3 0.4 0.5 0.7 0.0 2.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.6 1.8 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.5 0.1 0.0 0.0 GPR176 Gm1012 ENSG00000166073 "G protein-coupled receptor 176" Q14439 15 39799008-39920266 "G-protein coupled receptors, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 22.3;Excitatory neurons: 32.0;Inhibitory neurons: 56.8;Oligodendrocyte precursor cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 276.1;fHDF/TERT166: 186.5;U-138 MG: 119.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039943, HPA039979" Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA039943: AB_10697711, HPA039979: AB_2676782" "unprognostic (4.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (1.04e-2)" "unprognostic (2.75e-2)" "unprognostic (1.38e-3)" "unprognostic (9.32e-2)" "unprognostic (3.23e-2)" "unprognostic (2.74e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (9.38e-7)" "prognostic unfavorable (6.84e-5)" "unprognostic (2.23e-1)" "unprognostic (1.95e-1)" "unprognostic (3.26e-2)" 13.2 6.1 10.0 4.1 10.6 0.3 6.6 11.2 10.5 6.8 1.1 3.9 2.0 5.6 2.0 1.7 4.4 7.0 4.2 10.1 10.4 3.9 1.9 7.5 6.3 9.7 8.8 1.8 1.6 1.9 5.0 2.4 12.3 7.1 2.3 6.3 2.9 3.6 1.7 3.5 3.4 4.6 6.0 4.1 2.2 7.2 8.8 2.1 5.0 1.1 5.8 6.4 5.3 5.9 52.3 2.6 3.2 0.6 36.9 64.6 0.0 108.3 276.1 64.3 99.5 3.7 8.3 0.7 8.7 186.5 37.1 1.6 7.7 8.4 100.7 1.7 11.2 7.7 7.7 0.1 41.1 0.0 0.4 50.7 1.0 56.7 47.6 65.7 24.6 2.4 1.0 1.1 91.8 2.1 0.1 0.0 3.2 0.4 9.3 2.7 32.3 0.3 1.6 0.6 12.0 47.8 27.9 0.0 4.4 0.7 9.0 0.5 31.8 119.5 33.9 7.2 40.7 1.1 3.6 0.1 24.9 0.0 47.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 10.6 11.2 10.5 10.1 10.4 9.7 8.8 12.3 6.0 8.8 5.9 3.0 0.0 0.0 8.5 0.9 1.8 0.2 0.8 0.0 1.1 0.4 0.6 0.9 1.5 0.1 0.0 0.0 0.0 0.3 0.1 0.0 9.3 22.3 0.1 3.1 1.8 0.0 0.0 32.0 3.9 0.0 3.4 0.0 0.2 0.0 0.1 0.7 0.1 0.1 1.7 56.8 0.0 0.0 0.0 1.8 13.5 1.2 0.7 1.8 3.7 0.0 14.9 0.0 40.7 1.4 12.0 0.0 1.2 3.1 3.0 0.0 1.2 0.0 1.1 13.1 3.8 15.2 2.9 3.8 0.5 1.0 0.0 0.4 0.8 0.0 0.1 GPR18 ENSG00000125245 "G protein-coupled receptor 18" Q14330 13 99254732-99261744 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.7;lymphoid tissue: 38.9;testis: 13.0" "Group enriched" "Detected in some" 4 "Early spermatids: 172.6;Late spermatids: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 65.3;NK-cells: 52.9;T-cells: 41.9" "Group enriched" "Detected in some" 4 "Daudi: 8.1;THP-1: 20.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013873 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "HPA013873: AB_1849285" "unprognostic (3.87e-6)" "unprognostic (1.31e-3)" "unprognostic (3.22e-2)" "unprognostic (1.31e-6)" "unprognostic (2.89e-1)" "unprognostic (7.55e-4)" "unprognostic (4.27e-5)" "unprognostic (3.45e-3)" "unprognostic (2.31e-3)" "unprognostic (5.43e-2)" "unprognostic (9.70e-2)" "unprognostic (4.03e-1)" "unprognostic (3.20e-6)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (6.92e-3)" 0.4 0.1 0.2 12.2 0.3 9.7 0.2 0.7 0.4 0.3 0.9 0.9 1.0 0.4 0.2 0.5 0.2 1.2 0.3 0.2 0.1 0.3 0.9 0.7 38.9 0.7 0.2 0.1 0.1 0.0 0.1 0.1 0.4 0.4 1.0 0.0 0.9 0.1 0.1 0.3 4.1 0.2 0.1 10.5 1.5 13.0 0.3 7.9 0.4 0.1 32.5 2.1 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 2.9 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 20.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 3.5 0.0 0.2 1.9 0.5 24.4 5.5 41.3 65.3 22.1 34.0 12.6 53.3 41.9 38.9 2.2 52.9 5.3 12.5 6.4 13.1 0.2 0.3 0.7 0.4 0.2 0.1 0.7 0.2 0.4 0.1 0.3 0.4 0.2 0.0 1.3 0.3 44.7 0.3 0.0 0.0 0.0 1.0 0.1 0.3 1.0 0.0 0.6 0.0 0.0 0.0 14.4 0.1 0.0 0.0 172.6 1.3 0.2 0.2 1.2 6.1 0.4 0.0 0.0 0.2 1.1 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.3 1.2 190.5 0.9 3.9 0.0 0.0 0.6 0.0 18.6 0.5 0.1 0.0 0.1 1.2 1.4 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.2 1.8 0.4 0.0 0.3 0.0 20.5 0.1 0.1 0.1 GPR180 ITR ENSG00000152749 "G protein-coupled receptor 180" Q86V85 13 94601857-94634661 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047250 Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047250: AB_2679998" "unprognostic (3.91e-3)" "unprognostic (3.28e-1)" "unprognostic (4.16e-3)" "unprognostic (2.95e-1)" "unprognostic (1.17e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (6.71e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (2.49e-2)" "unprognostic (1.10e-1)" "unprognostic (8.47e-2)" "unprognostic (2.80e-2)" 5.8 2.3 3.0 2.4 3.6 0.9 2.6 4.5 4.5 2.7 4.1 2.1 2.0 2.4 1.8 1.7 2.5 1.8 1.8 3.4 3.2 2.5 6.9 2.4 2.4 2.8 3.0 2.4 3.1 2.5 3.5 3.6 3.1 2.5 2.5 7.0 2.8 2.3 1.8 1.9 1.6 2.8 3.6 2.2 2.7 1.1 3.2 2.6 3.6 1.8 2.6 2.3 1.5 3.6 14.6 3.6 5.1 5.4 10.5 11.4 2.1 9.7 7.7 9.3 12.3 4.4 9.8 4.8 4.1 8.4 6.4 9.0 7.3 6.9 12.7 12.7 4.6 9.4 4.9 0.0 8.3 13.6 7.3 6.5 5.8 5.7 7.7 8.3 9.6 6.8 2.7 2.3 9.3 2.1 6.9 3.0 3.3 10.4 4.0 7.8 6.8 2.0 10.4 4.3 7.4 5.3 4.5 9.9 12.2 6.4 7.0 5.5 8.7 5.7 4.6 6.8 8.2 3.8 4.2 2.2 9.5 10.9 7.9 0.1 0.5 0.1 0.8 0.3 1.4 0.5 0.9 0.6 0.9 0.5 1.1 0.9 0.0 0.5 0.4 0.6 1.2 0.4 3.0 3.6 4.5 4.5 3.4 3.2 2.8 3.0 3.1 3.6 3.2 3.6 9.0 3.2 4.1 20.2 6.1 6.0 5.4 11.2 7.4 12.5 7.4 5.5 6.8 7.2 7.8 12.9 31.3 8.7 9.3 3.8 5.9 8.3 1.0 11.1 8.9 8.3 10.3 3.6 47.6 10.2 27.8 11.8 9.7 9.0 5.1 9.2 9.7 30.8 10.5 18.5 30.5 9.8 6.1 4.4 4.9 0.7 9.6 5.3 7.2 18.7 4.1 15.4 9.2 40.7 26.3 9.6 3.7 5.7 16.0 10.6 3.0 7.5 16.8 22.0 6.6 6.3 10.6 3.5 10.6 6.4 4.7 4.1 6.6 3.6 5.5 5.0 GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416805-132646582 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 12.1;Early spermatids: 20.6;Late spermatids: 19.4;Oligodendrocyte precursor cells: 18.6;Spermatocytes: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "A-431: 32.0;CAPAN-2: 26.9;hTEC/SVTERT24-B: 30.8;RT4: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022111 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA022111: AB_1849298" "unprognostic (4.06e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (1.50e-2)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.28e-1)" "unprognostic (1.64e-1)" "unprognostic (3.72e-1)" "unprognostic (4.69e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" 0.2 0.0 0.7 0.9 0.7 0.0 2.1 0.5 0.7 4.4 1.3 6.8 4.6 0.4 0.8 0.8 3.6 2.2 0.0 0.4 0.7 2.6 3.3 3.9 0.0 1.6 2.2 0.0 3.9 5.1 0.1 0.1 2.0 0.5 5.7 0.0 0.5 1.0 0.0 1.0 3.7 0.3 1.2 0.0 6.1 0.2 0.7 0.0 1.3 0.0 0.2 2.6 0.6 0.2 32.0 18.1 0.3 0.0 0.5 3.6 0.0 2.8 11.1 5.8 3.3 17.7 26.9 0.0 9.7 1.9 13.1 18.6 0.0 12.9 5.7 0.1 0.0 0.0 1.9 0.7 0.6 0.0 0.0 1.1 9.7 30.8 3.1 7.0 0.1 0.0 0.0 0.0 4.2 3.0 0.0 0.0 0.3 7.3 10.5 0.0 0.5 0.0 21.2 27.9 0.0 0.1 2.0 10.3 0.1 1.1 5.8 0.0 5.6 12.4 12.2 4.2 16.8 0.0 0.0 0.1 18.9 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.7 0.5 0.7 0.4 0.7 1.6 2.2 2.0 1.2 0.7 0.2 0.0 16.0 8.7 12.1 0.0 0.1 0.7 2.4 0.0 0.2 1.5 0.9 0.2 2.8 6.7 0.0 0.0 0.0 2.7 10.3 0.0 5.6 20.6 2.6 0.2 0.1 2.4 0.0 3.9 3.1 0.0 0.2 4.1 1.8 0.0 0.0 0.0 3.6 0.0 0.0 4.9 1.6 0.0 0.6 0.3 19.4 0.3 0.3 0.0 1.0 0.6 1.4 0.0 18.6 1.8 5.9 3.0 0.4 0.1 0.3 1.9 0.7 6.1 0.0 0.0 0.1 0.3 32.4 1.2 0.5 0.0 0.0 0.0 0.0 4.9 1.2 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Cell type enhanced" "Detected in some" "Adipocytes: 26.7;Endothelial cells: 26.4;Hepatic stellate cells: 24.7;Sertoli cells: 6.6;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 18.7;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 40.6 6.9 7.0 3.3 6.2 0.5 22.1 6.0 8.8 4.9 6.2 4.2 0.9 7.4 0.7 2.6 6.0 3.3 23.8 5.6 5.9 24.6 3.6 28.6 0.9 8.0 7.5 3.5 3.7 1.4 5.9 4.0 8.6 5.8 0.7 0.9 2.9 0.9 5.7 2.9 5.1 2.5 6.5 4.1 5.6 1.7 10.7 0.5 18.2 2.5 0.6 7.0 4.9 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.7 1.1 0.0 0.1 0.0 2.0 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.8 0.0 0.0 0.3 0.3 0.0 18.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 31.3 0.1 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 6.2 6.0 8.8 5.6 5.9 8.0 7.5 8.6 6.5 10.7 6.3 26.7 0.0 0.5 0.7 0.1 2.4 0.2 0.0 1.2 0.1 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.3 26.4 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.2 0.0 0.0 24.7 0.1 0.3 0.0 0.2 0.0 0.0 1.2 1.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 6.6 0.6 16.8 0.0 0.2 0.1 1.3 0.0 0.1 0.3 0.0 0.3 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 192.7;stomach 1: 230.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3;Gastric mucus-secreting cells: 143.2;Hepatocytes: 183.6;Paneth cells: 153.8;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.7" "Cell line enhanced" "Detected in many" "Hep G2: 82.4;HMC-1: 146.7;PC-3: 80.8;RPTEC TERT1: 172.1;RT4: 89.9;T-47d: 108.0" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 16.1 19.3 17.4 3.1 18.4 0.4 20.1 48.9 18.1 42.0 28.0 38.7 25.0 17.1 10.2 12.2 30.0 21.3 33.7 14.8 16.9 135.7 192.7 23.0 2.1 18.1 18.7 38.2 136.1 28.2 14.8 11.9 18.6 45.6 14.6 1.5 37.4 24.3 110.1 43.9 30.3 4.0 16.6 22.3 230.3 4.0 17.0 4.4 74.8 33.9 3.0 30.8 20.9 15.7 17.3 61.6 3.8 5.5 0.0 0.0 0.2 0.3 0.0 0.0 0.0 66.4 73.0 0.0 45.0 0.3 18.5 52.9 7.7 1.0 0.1 0.2 10.7 0.0 4.0 82.4 15.8 0.0 146.7 1.3 26.7 0.0 0.0 69.2 0.0 0.1 4.8 1.2 0.0 18.0 0.7 17.2 9.2 79.5 80.8 0.2 0.1 2.8 172.1 89.9 27.5 2.5 3.7 5.9 0.1 33.1 108.0 4.6 0.0 0.0 5.5 0.1 0.1 0.1 0.4 0.2 6.5 2.5 0.4 0.0 1.1 0.1 0.0 2.5 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.7 7.9 0.0 0.3 17.4 18.4 48.9 18.1 14.8 16.9 18.1 18.7 18.6 16.6 17.0 15.7 11.2 3.2 57.7 13.4 1.4 13.6 39.2 79.6 26.7 0.8 27.3 19.4 211.3 67.2 76.2 136.1 0.0 0.8 11.8 74.9 29.4 65.5 0.1 62.5 6.6 20.9 45.5 5.3 0.1 68.1 20.3 11.3 143.2 74.9 10.2 0.1 48.2 183.6 12.3 5.0 0.5 50.8 69.2 16.3 4.6 1.7 18.0 6.3 3.6 2.8 4.1 15.9 0.0 5.0 0.2 41.2 153.8 22.2 1.2 44.6 61.0 73.5 45.4 1.5 144.7 4.7 64.0 0.5 5.0 14.8 11.2 25.3 2.4 1.5 48.5 63.1 GPRC5D ENSG00000111291 "G protein-coupled receptor class C group 5 member D" Q9NZD1 12 12940775-12952147 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skin 1: 47.8" "Cell type enhanced" "Detected in some" "Early spermatids: 6.8;Gastric mucus-secreting cells: 5.6;Late spermatids: 6.2;Melanocytes: 5.4;Plasma cells: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "memory B-cell: 21.9;naive B-cell: 7.5" "Lineage enriched" "Detected in many" 14 "B-cells: 21.9" "Group enriched" "Detected in many" 9 "Karpas-707: 84.5;RPMI-8226: 85.9;U-266/84: 25.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA071909 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 61: Skin - Cornification" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA071909: AB_2686470" "unprognostic (4.27e-2)" "unprognostic (8.58e-2)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (4.34e-2)" "prognostic favorable (5.09e-4)" "unprognostic (3.00e-5)" "unprognostic (4.06e-2)" "unprognostic (3.06e-2)" "unprognostic (5.53e-2)" "unprognostic (7.01e-2)" "unprognostic (2.27e-2)" "unprognostic (8.33e-3)" "unprognostic (9.54e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-2)" "unprognostic (6.63e-2)" 0.9 0.6 0.2 0.4 0.4 0.6 3.0 0.1 0.2 1.2 2.0 2.7 1.8 0.2 0.0 2.5 0.3 0.8 0.8 0.2 0.4 0.6 1.0 7.2 0.7 1.1 1.2 0.5 2.1 0.0 1.5 0.3 0.5 1.2 2.3 0.3 4.5 0.0 0.2 47.8 2.7 0.0 0.3 1.6 2.3 2.7 0.6 0.1 1.2 0.0 1.1 0.7 1.0 0.3 1.3 1.4 0.0 1.5 0.0 0.0 3.3 0.4 0.0 0.0 0.3 1.3 3.2 0.1 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 7.6 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.1 84.5 0.2 3.1 0.0 0.0 0.8 3.9 0.1 0.1 0.0 85.9 0.0 3.4 2.6 0.5 1.9 1.4 0.0 3.5 0.0 0.0 2.3 0.0 3.9 0.1 0.0 4.4 25.2 1.1 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 21.9 0.2 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.4 0.1 0.2 0.2 0.4 1.1 1.2 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 5.6 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.3 0.0 6.2 0.0 0.1 5.4 1.9 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 GPSM2 "DFNB82, LGN, Pins" ENSG00000121957 "G protein signaling modulator 2" P81274 1 108875350-108934545 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.9;tongue: 54.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 133.5;Oligodendrocyte precursor cells: 134.7;Oligodendrocytes: 127.4;Syncytiotrophoblasts: 89.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.2;T-reg: 1.8" "Group enriched" "Detected in many" 5 "granulocytes: 3.2;T-cells: 1.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007327, HPA008408, CAB018962" Uncertain Supported Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "CAB018962: , HPA007327: AB_1849941, HPA008408: AB_1849939" "unprognostic (1.97e-1)" "unprognostic (6.80e-2)" "prognostic favorable (7.86e-5)" "unprognostic (1.37e-3)" "unprognostic (3.18e-2)" "unprognostic (1.97e-2)" "unprognostic (8.57e-6)" "unprognostic (7.12e-2)" "unprognostic (2.76e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (7.55e-3)" "prognostic unfavorable (3.02e-4)" "unprognostic (6.27e-3)" "unprognostic (1.00e-1)" "unprognostic (5.14e-3)" "unprognostic (6.00e-2)" 5.3 3.5 27.3 4.4 39.5 14.4 7.5 33.8 25.2 12.6 10.8 15.3 9.1 6.8 2.6 34.1 4.2 2.6 4.3 23.3 29.5 2.3 2.9 9.0 6.4 33.9 36.3 3.3 3.6 9.7 3.1 7.7 33.9 5.9 15.2 8.6 10.1 4.7 10.7 37.7 11.5 10.5 32.1 2.7 5.1 11.5 34.1 18.4 3.2 54.4 13.2 6.0 17.7 46.9 135.6 16.2 36.8 27.7 36.4 20.2 30.0 24.2 61.4 29.9 45.4 16.0 31.7 30.5 6.7 33.4 21.0 28.3 25.3 59.1 39.6 30.7 15.8 19.8 34.7 16.5 4.8 28.6 18.5 4.1 113.9 29.4 129.8 9.4 26.9 19.5 14.9 42.3 58.4 37.8 26.1 12.2 8.7 52.1 29.4 20.1 66.7 6.6 24.3 18.6 30.4 26.9 37.0 69.2 26.9 10.3 27.6 24.3 18.0 21.7 36.7 64.8 48.5 18.4 20.9 28.6 34.3 47.4 108.9 0.1 0.3 3.2 0.2 0.3 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.3 0.3 0.1 0.1 0.1 1.8 0.1 27.3 39.5 33.8 25.2 23.3 29.5 33.9 36.3 33.9 32.1 34.1 46.9 4.6 16.0 3.3 63.0 5.7 62.7 18.8 12.9 47.3 47.7 3.0 3.7 2.5 2.8 12.5 7.3 133.5 46.3 6.7 10.8 11.7 2.5 54.0 5.2 20.6 5.1 9.1 33.9 11.7 1.9 47.7 19.5 8.6 9.2 2.5 14.4 2.9 1.6 9.0 43.7 24.0 14.1 10.2 5.3 11.3 21.3 18.6 4.9 26.6 3.7 5.3 8.0 2.1 134.7 127.4 4.8 7.8 5.3 5.3 5.6 8.4 0.9 9.0 48.1 0.0 43.6 6.9 20.6 28.9 24.0 40.6 89.2 7.1 10.0 18.7 15.5 GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 179.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.9;Hepatocytes: 237.3;Paneth cells: 88.4;Proximal enterocytes: 139.7;Proximal tubular cells: 164.9" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;Karpas-707: 2.8;U-266/70: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favorable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" 22.6 2.4 2.2 4.6 1.9 2.3 12.5 3.3 4.7 0.7 3.5 36.0 18.3 0.5 0.4 2.4 1.3 2.4 40.3 2.1 0.4 13.9 179.6 0.4 0.3 0.8 0.5 1.1 10.3 1.4 2.9 0.1 0.6 1.8 5.8 0.6 14.6 1.2 50.1 17.1 18.0 0.4 0.2 0.6 15.0 2.6 0.9 0.0 0.9 24.3 0.2 0.6 1.3 0.9 0.2 0.8 0.2 0.5 0.4 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.9 0.4 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.7 1.3 0.3 1.5 2.5 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.2 2.8 0.0 1.3 0.4 0.4 0.3 0.6 0.5 0.5 0.1 1.5 0.0 0.9 0.5 0.8 0.2 0.7 0.1 0.1 1.9 0.1 0.2 0.1 0.6 0.7 0.1 2.9 0.2 0.2 0.4 0.9 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.2 1.9 3.3 4.7 2.1 0.4 0.8 0.5 0.6 0.2 0.9 0.9 0.2 0.0 0.0 14.4 5.3 1.7 1.3 1.2 0.6 0.9 14.1 4.6 8.5 34.3 1.8 7.3 0.0 0.0 0.4 176.9 21.5 1.1 16.5 0.5 0.4 1.1 2.4 43.2 0.8 2.4 3.3 0.3 51.0 0.7 8.9 0.3 14.3 237.3 0.1 3.3 0.5 30.4 0.0 14.4 2.1 48.1 0.6 1.2 1.8 1.0 0.1 15.6 0.0 2.0 0.0 1.3 88.4 0.4 0.1 1.2 139.7 164.9 0.5 2.0 0.0 2.0 0.4 1.0 0.6 2.4 4.5 0.0 1.8 0.4 62.1 1.6 GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884362-46931289 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 267.4;skeletal muscle: 176.4;tongue: 184.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Hepatocytes: 123.9;Syncytiotrophoblasts: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 159.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA051514: AB_2681516" "unprognostic (1.65e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.95e-3)" "unprognostic (3.44e-2)" "unprognostic (6.12e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.44e-2)" "unprognostic (4.86e-1)" "unprognostic (3.54e-3)" "unprognostic (3.18e-1)" 56.8 10.4 51.6 4.0 49.9 3.8 17.0 49.1 56.9 5.2 38.4 7.7 1.7 3.7 31.4 77.8 7.6 9.8 7.9 51.3 45.7 23.5 103.7 2.1 4.3 69.8 45.9 2.3 267.4 8.3 13.0 3.1 63.9 24.2 4.9 6.9 48.8 10.9 176.4 37.8 3.9 3.1 60.2 2.3 58.6 15.0 54.9 7.7 7.6 184.5 13.4 2.7 7.7 64.5 42.6 19.0 23.8 90.6 32.7 7.0 43.1 28.9 10.9 30.7 19.2 65.3 17.6 29.9 24.7 20.7 15.6 33.6 43.3 42.8 20.4 14.0 21.1 10.5 10.8 159.9 22.4 75.6 9.5 15.2 37.0 30.0 46.3 20.3 15.1 56.1 8.7 23.3 10.3 75.8 15.1 62.9 25.3 52.2 54.2 0.3 26.3 71.1 12.4 21.0 73.7 37.7 14.9 76.4 39.0 9.4 19.6 67.6 11.3 21.1 40.9 14.2 23.4 110.2 36.9 87.1 32.6 48.3 11.7 0.4 0.2 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 51.6 49.9 49.1 56.9 51.3 45.7 69.8 45.9 63.9 60.2 54.9 64.5 1.3 6.4 3.4 54.9 4.8 15.9 4.9 6.8 64.3 14.5 6.7 8.4 14.9 8.6 9.1 18.4 22.9 9.2 0.3 10.2 11.7 7.0 9.6 12.2 7.2 2.3 13.1 5.2 16.7 30.2 44.8 7.5 37.2 37.5 3.8 14.9 5.0 123.9 3.8 6.7 18.8 13.4 6.1 3.2 7.3 22.9 4.7 2.3 8.8 1.0 1.1 42.5 1.0 13.6 26.0 25.6 5.2 15.4 7.9 12.4 2.0 38.6 5.4 5.9 0.0 5.2 3.6 2.5 17.3 53.1 16.3 83.3 1.4 2.6 6.3 4.2 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GPX3 ENSG00000211445 "Glutathione peroxidase 3" P22352 5 151020438-151028992 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 11673.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 20125.9" "Cancer enhanced" "Detected in all" "renal cancer: 605.6;thyroid cancer: 856.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 20.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.7" "Cell line enriched" "Detected in many" 12 "ASC diff: 7677.4" "Region enhanced" "Detected in all" "hypothalamus: 239.5" "Low region specificity" "Detected in all" CAB069456 Approved "Secreted to blood" NA NA 5090000000 6200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB069456: AB_1616682" "unprognostic (4.03e-1)" "unprognostic (7.35e-2)" "unprognostic (5.05e-3)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.13e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (5.75e-3)" "unprognostic (2.70e-3)" "unprognostic (8.17e-3)" "unprognostic (1.14e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (2.14e-1)" "unprognostic (5.11e-2)" "unprognostic (1.26e-1)" 4524.7 443.8 57.8 75.4 68.3 7.9 3188.6 62.7 73.8 917.6 578.2 741.2 88.3 416.0 90.7 568.6 1038.4 136.4 2362.4 68.2 117.5 11673.5 986.3 2471.8 133.2 317.7 104.5 517.8 257.0 112.4 793.7 592.2 136.6 557.5 93.4 4204.9 481.4 140.0 847.9 669.7 720.6 61.0 67.5 555.7 641.1 80.4 135.8 26.8 3627.5 458.9 44.9 1196.7 891.7 70.3 2.2 10.0 8.5 2.7 7677.4 6.7 9.2 3.5 0.8 7.9 2.4 177.5 3.9 1.1 214.1 5.6 3.2 2.8 39.6 433.2 6.0 6.1 2.5 1.9 4.3 195.0 294.7 0.5 4.3 649.1 41.2 0.2 1.0 10.6 11.3 1.2 1.2 0.3 11.0 31.4 0.5 1.2 13.8 0.8 0.2 1.0 5.2 1.7 74.1 4.3 11.3 11.4 1.2 31.6 1.9 33.6 43.5 2.1 2.5 2.3 19.6 3.7 1.0 2.7 15.6 2.5 7.0 3.0 0.6 0.0 4.3 0.1 0.0 1.6 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 20.7 0.0 0.2 0.0 0.0 1.6 57.8 68.3 62.7 73.8 68.2 117.5 317.7 104.5 136.6 67.5 135.8 70.3 353.6 9.6 33.7 1.0 106.8 18.5 86.9 94.8 1.2 26.3 31.7 5.5 639.8 18.6 58.3 649.2 43.8 713.8 2.2 2.3 1772.6 5.5 2.9 48.1 71.1 144.6 45.6 24.0 4.0 48.2 1191.3 514.0 50.0 627.9 11.4 274.9 735.3 228.4 151.5 16.8 0.4 5.9 91.6 47.9 86.7 17.5 446.7 160.2 23.2 3.7 0.7 5019.8 0.0 0.0 0.3 9.9 13.8 41.0 2.2 141.8 0.5 20125.9 39.1 86.8 683.7 131.6 264.6 7.1 10.3 13.9 21.6 1767.7 68.3 1.0 1.3 34.3 GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103926-1106791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 18580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749" "unprognostic (8.42e-3)" "prognostic favorable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favorable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favorable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 927.8 535.3 415.1 127.4 428.7 178.0 733.3 440.7 519.1 280.8 478.7 249.0 259.0 188.4 318.9 220.4 199.2 196.6 426.0 419.2 450.3 536.5 687.8 307.9 216.4 430.9 448.3 260.3 157.9 285.5 398.4 147.2 454.1 322.1 110.9 167.5 304.9 193.8 672.3 290.4 236.2 87.9 418.2 213.2 219.0 1403.5 444.0 158.7 291.5 399.7 182.5 319.0 245.2 429.1 258.1 286.8 405.8 863.0 1202.1 706.0 449.3 199.3 713.5 371.1 375.9 590.5 339.8 92.8 211.8 405.8 313.5 283.1 239.7 289.3 180.5 522.3 436.5 175.0 246.9 849.2 697.4 207.6 269.4 707.3 432.1 188.3 314.7 665.9 527.1 317.5 249.4 225.7 311.1 660.4 353.8 354.9 386.2 569.7 458.9 482.8 55.3 271.3 408.9 629.9 348.3 220.6 390.5 366.1 422.1 246.7 358.1 498.0 450.9 392.3 257.4 680.6 254.6 786.5 582.0 224.3 369.4 412.2 230.9 578.9 539.6 564.4 219.8 405.4 256.9 352.7 319.7 230.7 404.0 309.9 339.4 245.0 265.1 196.6 462.2 278.8 310.3 841.7 415.1 428.7 440.7 519.1 419.2 450.3 430.9 448.3 454.1 418.2 444.0 429.1 415.9 179.5 189.7 21.2 281.7 510.0 525.8 1188.1 512.2 332.2 845.1 868.2 264.6 316.0 600.6 472.6 98.0 562.5 231.3 479.1 1592.6 515.8 4209.7 546.8 326.3 268.7 397.1 215.0 24.5 368.7 1327.3 536.1 99.9 442.3 346.1 242.6 322.0 826.2 1184.1 208.6 33.1 328.7 671.4 583.1 1304.8 18580.2 384.9 735.2 677.7 21.5 1786.8 502.6 192.6 13.6 35.4 484.0 507.9 312.9 189.2 694.7 1861.9 3024.7 800.9 246.0 243.3 244.6 587.1 1310.8 202.4 357.7 467.0 978.1 281.0 186.7 336.4 662.6 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GRAMD2A GRAMD2 ENSG00000175318 "GRAM domain containing 2A" Q8IUY3 15 72159806-72197787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 35.9;placenta: 48.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 70.5;Cytotrophoblasts: 106.2;Extravillous trophoblasts: 29.5;Syncytiotrophoblasts: 147.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 165.5;SK-BR-3: 75.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029435 Uncertain Approved "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nuclear speckles" Cytosol "HPA029435: AB_10601811" "unprognostic (5.70e-2)" "unprognostic (7.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.24e-1)" "unprognostic (9.51e-3)" "unprognostic (2.95e-1)" "unprognostic (9.96e-2)" "unprognostic (3.90e-3)" "unprognostic (2.80e-1)" "unprognostic (1.96e-1)" "unprognostic (2.62e-1)" "unprognostic (5.77e-2)" "unprognostic (4.45e-1)" "unprognostic (2.35e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (7.29e-2)" 0.0 0.0 2.1 0.5 1.7 0.0 10.2 2.0 1.3 1.9 2.1 1.2 1.0 0.4 35.9 1.1 5.8 0.3 0.1 2.2 3.9 3.2 0.0 15.0 0.4 6.5 13.1 0.1 0.5 0.1 0.7 48.7 10.1 1.3 0.8 0.9 2.1 5.2 0.0 2.5 3.3 0.2 2.6 0.2 0.8 0.4 3.0 0.2 8.9 0.0 0.4 0.3 0.7 2.0 2.1 0.0 0.1 0.0 0.0 0.0 165.5 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.6 0.0 0.0 1.2 0.0 10.0 0.2 0.0 0.2 0.3 0.1 0.0 1.2 0.0 0.0 0.1 2.1 0.0 7.5 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.5 0.6 0.0 0.1 0.0 0.1 0.2 0.1 1.7 0.1 0.3 75.8 0.1 5.5 3.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.7 2.0 1.3 2.2 3.9 6.5 13.1 10.1 2.6 3.0 2.0 0.1 70.5 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.3 0.0 0.0 7.4 3.7 0.0 106.2 0.1 0.0 0.0 0.1 0.0 14.0 0.2 0.2 0.0 0.0 0.0 0.0 29.5 0.8 0.0 0.7 1.3 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 10.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 147.1 0.3 0.1 0.0 0.0 GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 278.3" "Cell type enriched" "Detected in many" 9 "Granulosa cells: 545.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.3;Hep G2: 39.6;MCF7: 61.8;SH-SY5Y: 40.5;SK-MEL-30: 30.4;T-47d: 138.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Mitochondria, Cytosol" "HPA024616: AB_10599728, HPA027843: AB_10601103, HPA028416: AB_10601344" "unprognostic (1.52e-2)" "unprognostic (4.63e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-1)" "unprognostic (3.63e-2)" "unprognostic (7.51e-4)" "unprognostic (2.42e-2)" "unprognostic (3.34e-1)" "unprognostic (2.46e-3)" "unprognostic (4.80e-2)" 1.8 3.4 8.5 0.7 9.6 0.4 13.7 2.1 9.9 60.2 0.8 1.0 0.7 61.3 7.0 0.6 53.4 2.8 4.6 7.8 20.4 1.8 3.1 1.4 0.6 8.7 8.5 278.3 7.6 0.7 8.9 3.0 4.4 63.4 0.2 1.5 1.1 3.8 4.0 2.7 0.9 12.8 3.2 0.2 3.0 14.9 10.7 0.3 0.6 4.8 0.3 1.7 21.5 6.5 0.1 1.0 40.3 0.5 0.2 0.2 1.8 0.0 0.1 0.1 0.3 0.3 0.2 2.5 0.3 0.0 6.9 0.2 3.1 0.2 0.1 5.1 3.6 0.4 0.3 39.6 0.5 0.3 2.1 0.5 2.2 0.6 0.4 0.4 0.0 3.9 0.5 1.0 0.3 61.8 1.2 2.0 13.0 0.1 0.1 29.1 0.0 1.9 0.1 0.0 11.8 40.5 0.9 1.1 30.4 5.2 138.0 0.7 0.0 4.1 2.0 0.4 0.1 6.0 4.4 24.7 6.8 11.9 1.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.1 0.1 0.0 8.5 9.6 2.1 9.9 7.8 20.4 8.7 8.5 4.4 3.2 10.7 6.5 0.4 0.0 0.5 20.2 0.7 0.8 1.9 0.0 0.6 4.8 24.7 13.7 8.3 5.7 0.6 0.0 2.1 0.2 0.1 0.1 0.0 0.3 0.8 35.7 36.0 1.3 0.0 0.0 15.0 0.2 3.6 16.9 0.0 23.4 3.8 545.2 0.7 8.9 3.2 3.3 46.9 0.0 0.0 0.0 1.2 2.5 20.2 1.4 5.4 1.0 0.0 0.2 0.0 11.6 20.9 0.4 0.0 55.3 5.0 14.3 0.0 2.5 2.9 0.5 0.0 7.2 14.8 1.1 2.9 0.3 0.3 0.3 1.1 33.1 0.0 2.5 GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;retina: 17.8" "Group enriched" "Detected in some" 5 "Excitatory neurons: 468.4;Horizontal cells: 198.5;Inhibitory neurons: 396.3;Oligodendrocyte precursor cells: 385.0" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 23.8;BJ hTERT+: 34.5;fHDF/TERT166: 45.9;U-2197: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" 0.8 10.3 20.0 0.3 25.3 0.1 1.4 1.3 31.6 6.7 0.0 0.7 0.3 2.1 3.6 0.4 1.5 1.2 2.0 29.0 4.0 2.5 7.7 0.3 0.5 1.9 3.4 4.1 1.7 0.0 1.0 0.4 1.4 1.7 0.8 17.8 0.2 1.9 0.2 0.5 0.5 1.9 4.5 0.1 2.0 0.7 6.4 0.2 0.2 0.1 0.8 0.6 2.8 20.9 0.0 0.0 0.0 0.0 2.2 0.4 0.0 23.8 34.5 0.4 0.9 0.0 0.0 0.0 0.0 45.9 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 6.6 0.0 15.1 0.2 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 25.3 1.3 31.6 29.0 4.0 1.9 3.4 1.4 4.5 6.4 20.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.8 0.6 13.6 0.2 0.0 1.6 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.1 0.3 8.7 0.3 0.0 0.0 468.4 0.2 0.1 6.4 1.1 0.2 0.0 0.1 0.4 6.1 0.1 198.5 396.3 0.0 0.0 0.0 1.5 0.3 9.3 0.2 1.8 14.0 0.0 1.9 0.0 385.0 67.6 0.3 0.0 4.1 0.0 0.4 0.0 6.2 0.1 3.8 0.0 0.2 4.5 0.0 0.1 0.0 1.0 0.1 0.1 0.7 0.0 0.0 GRID1 "GluD1, KIAA1220" ENSG00000182771 "Glutamate ionotropic receptor delta type subunit 1" Q9ULK0 10 85599552-86366795 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.4" "Group enriched" "Detected in some" 19 "Astrocytes: 149.8;Excitatory neurons: 284.5;Inhibitory neurons: 301.2;Oligodendrocyte precursor cells: 316.2;Oligodendrocytes: 534.1" "Group enriched" "Detected in many" 5 "glioma: 3.6;thyroid cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.4;HEL: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (7.60e-2)" "unprognostic (2.75e-2)" "unprognostic (5.92e-2)" "unprognostic (4.31e-2)" "unprognostic (4.24e-1)" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.21e-2)" "unprognostic (5.09e-2)" "unprognostic (1.49e-3)" "unprognostic (8.30e-2)" "unprognostic (8.26e-2)" "unprognostic (4.58e-9)" "unprognostic (3.15e-3)" "unprognostic (5.91e-2)" "unprognostic (2.21e-1)" "unprognostic (8.65e-3)" 0.6 0.9 5.3 0.1 5.7 0.0 0.8 3.9 6.9 1.5 0.1 0.3 0.3 1.0 0.7 0.2 1.2 0.2 0.2 5.5 5.4 0.1 0.1 0.4 0.3 5.4 5.4 0.3 0.2 0.2 0.2 0.7 4.8 0.4 0.1 0.7 0.1 0.9 0.2 0.4 0.3 0.4 5.6 0.0 0.4 0.9 5.7 0.1 2.0 0.0 0.2 0.1 0.6 7.4 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.6 2.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.7 3.9 6.9 5.5 5.4 5.4 5.4 4.8 5.6 5.7 7.4 1.1 3.2 0.5 149.8 0.0 0.5 0.1 0.1 2.2 10.5 0.0 0.1 1.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.3 1.0 0.0 0.3 0.3 0.0 0.0 284.5 0.2 0.0 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 301.2 0.0 0.0 0.0 0.4 3.0 2.1 0.2 5.4 15.9 0.0 0.8 0.0 316.2 534.1 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.0 0.5 13.1 0.2 5.7 0.1 0.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "adrenal gland: 12.5;brain: 32.6;retina: 38.2" "Group enriched" "Detected in some" 10 "Inhibitory neurons: 2260.1;Oligodendrocyte precursor cells: 862.5" "Cancer enriched" "Detected in some" 5 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA014623: AB_1850305, HPA073879: " "unprognostic (1.39e-1)" "unprognostic (6.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.20e-3)" "unprognostic (1.47e-8)" "unprognostic (2.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" 0.2 12.5 7.5 0.2 6.6 0.1 1.8 2.4 6.0 0.8 0.0 0.3 0.0 0.1 2.0 0.3 0.0 0.1 0.0 8.4 12.3 0.0 0.1 0.1 0.1 30.0 11.2 0.3 0.0 0.0 0.2 0.4 32.6 2.4 0.5 38.2 0.0 0.1 0.1 0.8 0.4 0.1 2.6 0.1 0.2 0.5 9.7 0.0 0.0 0.0 0.0 0.4 0.4 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 6.6 2.4 6.0 8.4 12.3 30.0 11.2 32.6 2.6 9.7 2.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.0 0.0 149.8 2.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.8 0.1 1.2 0.4 0.0 0.0 29.8 0.0 0.0 0.7 0.0 0.2 0.0 148.8 0.0 0.0 0.1 1.7 2260.1 0.0 0.0 0.0 0.4 13.2 0.3 0.2 3.6 10.3 0.0 2.5 0.0 862.5 8.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.1 33.8 0.1 0.0 GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 432.6;monocytes: 355.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (2.73e-3)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" "unprognostic (3.72e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" "unprognostic (3.13e-3)" "unprognostic (1.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.43e-2)" "unprognostic (6.75e-2)" "unprognostic (5.72e-2)" 273.1 218.3 154.1 109.0 147.4 215.1 236.4 143.9 226.4 178.9 99.4 144.9 72.1 137.8 79.7 134.2 149.0 74.5 154.8 158.9 149.8 200.8 447.1 233.9 77.7 151.6 155.6 152.7 97.2 144.4 127.7 86.2 160.5 176.0 33.2 180.7 116.7 181.7 145.4 167.1 138.1 75.1 152.1 311.3 104.6 269.4 163.1 58.5 187.4 57.4 55.2 162.1 139.3 140.2 79.3 155.9 76.4 129.5 392.6 196.9 114.5 112.5 258.9 184.4 168.7 95.5 64.3 57.9 120.2 249.7 128.6 69.8 136.8 162.3 75.5 83.1 95.9 60.2 85.9 114.5 412.0 12.7 90.7 254.2 441.0 132.7 193.3 194.5 90.1 23.9 56.1 76.8 160.7 489.5 34.7 32.6 53.4 75.8 231.2 45.4 39.9 111.4 93.2 229.1 52.3 84.8 163.5 177.9 225.8 104.1 342.2 77.6 91.8 115.4 127.1 158.0 82.1 124.3 78.3 44.6 147.4 79.0 67.6 1.8 32.0 9.7 2.5 36.4 3.5 8.3 2.5 2.9 13.3 7.1 4.5 4.1 18.6 3.3 36.1 22.9 2.3 16.0 154.1 147.4 143.9 226.4 158.9 149.8 151.6 155.6 160.5 152.1 163.1 140.2 54.5 19.2 52.7 35.3 45.4 37.2 32.5 58.7 121.3 91.1 62.7 79.4 23.2 45.8 27.9 53.3 79.2 137.2 22.6 29.1 23.5 75.0 273.8 36.8 56.1 47.7 42.1 60.0 21.3 69.1 55.8 67.7 16.8 36.1 16.4 76.2 51.4 194.5 178.4 33.7 26.6 24.3 42.7 225.1 86.7 432.6 61.5 184.3 37.4 22.5 355.1 89.9 6.2 12.5 9.3 66.0 54.5 67.7 44.4 46.7 72.9 73.6 29.4 95.8 46.0 32.4 45.6 96.0 16.9 83.2 36.9 264.2 20.8 38.7 31.4 25.5 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Microglial cells: 56.2;Sertoli cells: 59.2;Smooth muscle cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;HUVEC TERT2: 24.9;OE19: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 38.4 18.0 4.2 5.9 5.0 2.7 24.6 5.0 4.6 18.8 3.5 26.3 10.0 21.1 3.5 12.6 19.6 5.7 48.8 4.0 5.1 14.2 12.9 65.6 7.8 3.9 3.6 35.0 4.7 21.3 13.3 8.3 3.9 14.1 4.9 1.0 7.8 4.0 11.9 11.5 25.8 7.3 3.3 37.0 27.5 4.1 4.9 6.2 19.6 9.7 6.8 19.4 18.1 3.5 3.7 2.3 5.4 5.7 11.8 11.0 1.6 7.1 32.1 4.1 2.3 1.7 5.4 3.9 1.6 11.1 7.5 0.9 2.3 7.7 2.7 15.4 2.0 0.7 4.6 7.0 8.2 0.2 2.0 1.5 1.1 8.5 1.2 5.2 24.9 2.4 0.4 3.7 1.5 0.7 3.8 3.5 0.8 25.8 5.2 1.3 0.8 0.9 0.6 1.5 1.8 4.9 2.4 1.1 7.0 3.0 0.1 0.9 7.8 2.3 1.6 14.6 2.8 0.9 4.4 2.4 4.9 4.4 2.4 0.4 1.5 2.9 2.0 1.4 0.1 3.8 3.0 1.6 0.9 4.0 4.5 2.0 2.1 0.1 0.5 0.0 4.0 1.7 4.2 5.0 5.0 4.6 4.0 5.1 3.9 3.6 3.9 3.3 4.9 3.5 32.6 57.7 3.7 3.6 19.7 1.7 0.7 0.5 1.2 3.9 2.3 2.0 19.4 0.0 1.3 3.7 0.0 3.7 13.3 0.4 0.0 1.1 18.7 0.4 5.1 28.4 4.8 0.0 17.7 3.1 15.8 35.7 18.8 1.0 4.5 7.8 24.7 2.2 4.4 1.7 36.5 0.8 6.1 15.5 6.3 4.9 4.4 14.2 7.2 56.2 3.6 0.0 19.6 14.1 5.7 2.4 1.2 4.5 10.2 0.7 4.9 0.6 0.8 0.9 59.2 18.2 46.5 1.3 2.1 0.7 2.4 13.1 14.1 4.6 0.5 0.9 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.1;Distal tubular cells: 41.1;Extravillous trophoblasts: 26.5;Hofbauer cells: 39.9;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.0;myeloid DC: 5.9;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019306: , HPA011326: AB_1847629" "unprognostic (1.08e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" "unprognostic (6.36e-3)" "unprognostic (6.70e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-3)" "unprognostic (1.48e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" 13.5 7.8 16.4 2.9 16.7 0.5 7.6 13.3 18.0 17.3 9.2 6.4 7.7 24.8 15.3 3.6 14.3 8.5 9.7 18.1 15.0 13.3 4.5 4.4 5.8 19.4 18.7 16.9 2.6 7.3 7.0 35.0 16.1 7.5 2.4 6.3 3.1 21.1 7.8 3.0 26.8 15.1 16.5 1.8 3.9 12.9 14.1 5.8 14.5 5.2 3.8 15.0 10.1 26.6 31.4 21.7 9.6 41.2 51.4 28.6 16.4 24.1 63.6 24.5 34.3 22.9 1.1 0.5 20.6 66.4 81.7 20.5 5.8 105.4 42.8 0.1 2.1 0.8 39.3 48.0 43.0 0.1 1.5 31.3 75.3 43.5 103.1 73.0 42.3 13.8 3.0 5.2 55.3 0.4 1.9 0.8 10.2 0.1 15.7 0.2 33.6 0.0 74.5 21.9 0.4 60.0 36.5 0.6 42.3 24.3 2.2 2.8 27.9 23.1 39.7 31.6 29.2 2.4 0.6 15.5 69.8 0.1 5.8 0.0 1.9 0.0 0.0 0.2 0.0 9.0 0.1 0.0 5.9 8.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 16.4 16.7 13.3 18.0 18.1 15.0 19.4 18.7 16.1 16.5 14.1 26.6 1.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.0 0.0 0.6 5.5 0.0 168.1 0.0 0.0 41.1 1.9 0.0 0.7 16.9 1.3 0.0 0.0 0.0 0.9 26.5 4.3 0.0 1.0 0.0 4.8 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 8.8 1.5 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 104.7 0.7 0.9 0.0 0.0 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GTDC1 "FLJ11753, Hmat-Xa" ENSG00000121964 "Glycosyltransferase like domain containing 1" Q4AE62 2 143938068-144332568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 330.7;Inhibitory neurons: 188.0;Microglial cells: 130.2;Oligodendrocyte precursor cells: 196.6;Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036694 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA036694: AB_10671709" "unprognostic (1.44e-1)" "unprognostic (1.22e-1)" "unprognostic (9.00e-3)" "unprognostic (3.36e-2)" "unprognostic (5.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-7)" "unprognostic (8.01e-2)" "unprognostic (4.13e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-3)" "unprognostic (6.96e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.44e-1)" "unprognostic (8.23e-2)" "unprognostic (6.31e-3)" "unprognostic (1.89e-1)" 15.2 12.6 15.9 7.5 18.0 14.2 9.4 11.7 21.1 11.8 4.2 7.1 4.2 6.7 9.4 7.4 5.8 10.1 15.7 17.3 14.3 9.6 6.7 7.8 11.0 15.4 14.7 12.0 7.2 7.4 4.2 9.5 15.4 6.1 6.7 7.7 6.1 5.8 10.0 5.1 4.8 5.9 17.2 13.5 5.2 12.2 14.3 8.7 10.5 11.3 11.6 9.5 5.5 24.1 6.9 2.8 20.0 3.7 20.1 18.4 6.0 4.7 11.9 10.3 14.2 3.1 6.3 14.8 3.3 8.5 6.6 1.9 4.0 7.1 21.9 19.2 4.7 23.0 2.6 3.3 8.3 9.4 12.0 12.8 17.1 11.1 16.2 7.0 14.9 6.1 4.2 16.8 23.7 3.2 2.5 10.3 5.7 5.3 4.5 7.0 10.4 4.0 11.4 14.0 10.2 7.9 9.1 7.7 9.3 12.4 5.1 10.5 9.2 11.4 8.3 5.1 6.0 10.6 0.0 8.5 6.6 6.2 15.6 2.3 2.6 7.9 5.5 2.4 11.8 4.3 3.6 9.3 2.1 3.5 0.8 5.9 11.3 8.5 2.7 0.7 5.1 3.6 15.9 18.0 11.7 21.1 17.3 14.3 15.4 14.7 15.4 17.2 14.3 24.1 7.7 9.6 23.2 82.3 11.2 7.1 4.4 6.4 4.0 20.4 5.2 5.0 18.5 4.3 14.9 5.5 4.2 4.1 13.6 6.1 5.9 4.5 9.9 3.3 11.4 9.6 4.2 9.4 330.7 10.5 5.2 16.0 4.6 5.6 17.7 15.5 20.3 3.8 10.2 18.5 188.0 3.2 4.1 18.3 11.8 7.7 12.8 16.4 5.4 130.2 11.6 10.8 18.6 196.6 399.6 9.4 4.0 13.9 8.6 4.2 2.6 7.7 13.4 3.9 13.1 25.2 17.0 5.4 23.5 4.9 4.7 4.2 19.7 14.8 3.7 8.7 GTF3A "AP2, TFIIIA" ENSG00000122034 "General transcription factor IIIA" Q92664 13 27424619-27435823 "Predicted intracellular proteins, Transcription factors" "Ribosome biogenesis, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007990 Supported Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 52: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA007990: AB_1857960" "unprognostic (9.88e-3)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (1.36e-1)" "unprognostic (2.87e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (8.64e-2)" "unprognostic (7.53e-2)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (3.41e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (1.98e-1)" "unprognostic (1.33e-1)" "unprognostic (3.26e-1)" "unprognostic (1.41e-1)" 63.5 40.3 51.0 50.3 53.0 85.3 59.3 53.1 63.0 31.9 50.4 41.8 30.3 26.6 57.4 38.3 32.8 33.4 126.7 52.8 51.9 52.5 129.8 33.2 81.2 53.2 53.3 16.0 116.4 34.5 26.9 28.4 52.7 30.7 40.4 10.4 70.4 34.8 89.3 25.0 32.3 38.0 53.0 54.6 46.9 17.4 52.9 111.6 31.2 132.6 89.8 46.0 23.7 56.2 91.2 78.8 65.4 136.8 90.4 98.8 93.3 95.1 86.0 118.3 75.4 118.5 139.4 275.3 65.9 112.6 73.9 64.9 136.6 131.0 165.8 289.2 93.1 229.9 71.6 135.4 102.5 432.3 150.9 81.5 137.9 109.2 142.4 81.8 107.2 246.9 184.2 88.6 140.5 178.3 311.3 467.9 115.8 299.6 210.7 154.8 169.3 254.0 142.5 39.2 158.9 81.5 67.6 101.6 141.7 83.7 73.7 223.6 66.0 62.5 67.1 49.3 99.1 57.0 104.9 275.1 67.1 264.9 117.4 116.8 173.8 162.5 250.2 180.1 335.2 290.5 251.6 271.7 218.4 250.3 192.5 219.6 38.3 243.7 169.5 298.3 345.1 484.4 51.0 53.0 53.1 63.0 52.8 51.9 53.2 53.3 52.7 53.0 52.9 56.2 96.9 44.8 33.0 15.0 183.3 63.2 62.4 109.1 56.3 41.7 107.2 117.6 207.8 91.5 58.3 27.6 29.2 76.3 207.1 20.0 150.6 195.7 33.9 60.1 68.1 76.3 34.8 126.4 28.7 190.6 187.4 75.0 63.2 49.1 75.5 93.0 40.0 146.7 215.5 35.3 25.8 60.6 77.3 156.1 119.3 85.6 63.6 133.9 97.8 15.9 185.3 73.1 236.9 7.1 24.3 153.3 28.9 58.3 248.4 122.7 35.6 207.7 37.9 35.7 85.5 58.3 76.1 34.8 145.1 83.4 64.4 42.1 187.1 89.0 69.8 70.3 GUCD1 "C22orf13, LLN4, MGC1842" ENSG00000138867 "Guanylyl cyclase domain containing 1" Q96NT3 22 24540423-24555935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 161.3;Proximal enterocytes: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022786 Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA022786: AB_1845711" "unprognostic (1.58e-1)" "prognostic favorable (6.84e-4)" "unprognostic (2.83e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (1.61e-1)" "unprognostic (3.96e-2)" "unprognostic (1.89e-1)" "prognostic favorable (7.26e-4)" "unprognostic (1.28e-1)" "unprognostic (3.55e-2)" "unprognostic (1.76e-2)" "unprognostic (4.36e-2)" "unprognostic (8.63e-2)" "unprognostic (1.59e-1)" "unprognostic (3.01e-2)" 36.9 27.5 19.3 25.3 22.0 89.9 29.2 20.5 18.9 19.6 17.7 37.5 67.5 19.1 16.7 25.2 21.1 25.4 62.0 17.0 19.8 43.0 93.9 34.3 34.6 23.4 23.4 19.4 37.1 24.1 12.3 21.6 21.3 31.0 36.2 10.9 25.0 20.2 96.4 27.6 59.6 23.1 22.1 30.4 37.1 18.8 23.1 27.9 16.6 117.6 36.9 26.8 19.8 22.2 40.8 37.1 30.9 38.5 62.5 58.4 25.7 38.7 59.5 63.3 61.0 56.9 30.2 72.1 26.0 50.9 39.3 51.2 35.2 43.3 33.6 74.2 45.4 31.3 36.1 51.3 50.6 83.2 63.2 59.6 33.9 64.0 29.0 38.7 67.5 35.9 32.3 75.6 48.4 47.2 49.2 34.1 31.0 95.3 30.6 57.2 52.0 73.1 49.8 44.9 33.8 33.2 47.2 60.6 33.3 23.6 49.6 56.7 48.7 143.4 59.8 44.5 34.6 70.1 53.8 50.8 57.9 45.3 49.9 20.2 14.9 52.5 7.4 14.8 8.5 37.0 7.1 7.7 13.7 42.6 6.7 7.6 15.2 7.5 14.5 9.7 7.6 13.8 19.3 22.0 20.5 18.9 17.0 19.8 23.4 23.4 21.3 22.1 23.1 22.2 20.5 16.0 33.9 6.8 41.5 12.4 11.8 13.9 21.1 5.3 25.9 18.3 51.2 78.6 13.3 5.5 6.2 18.6 21.2 99.7 52.8 27.1 15.8 13.4 13.6 16.4 19.8 86.1 2.3 66.0 20.1 17.5 35.7 17.9 15.2 19.5 18.5 161.3 27.1 3.3 3.0 52.3 16.2 23.5 12.0 8.6 19.0 21.0 17.8 2.8 28.6 18.2 18.6 5.5 7.5 48.1 72.4 16.1 17.5 32.1 149.6 84.9 9.7 13.2 26.3 12.4 16.7 24.3 32.0 18.7 11.1 16.3 14.6 28.9 36.7 18.9 GUCY1A2 "GC-SA2, GUC1A2" ENSG00000152402 "Guanylate cyclase 1 soluble subunit alpha 2" P33402 11 106674019-107018476 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;placenta: 17.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 353.8;Inhibitory neurons: 141.8;Oligodendrocyte precursor cells: 208.6;Sertoli cells: 105.2;Smooth muscle cells: 107.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.8;BJ hTERT+ SV40 Large T+ RasG12V: 13.4;HBF TERT88: 7.1;TIME: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009534 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB009534: AB_2279509" "unprognostic (7.53e-2)" "unprognostic (6.67e-2)" "unprognostic (7.99e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-2)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (6.53e-3)" "unprognostic (9.70e-3)" "unprognostic (8.00e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.48e-4)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" 3.4 2.0 5.3 0.6 18.4 0.0 1.9 1.6 13.8 12.7 0.0 0.7 0.2 12.3 3.1 0.4 5.9 1.5 2.7 7.1 3.9 1.8 1.7 4.6 0.7 4.7 2.6 1.2 4.3 0.6 0.5 17.9 4.9 1.8 0.5 3.5 0.6 6.8 1.8 0.6 0.4 13.1 0.4 6.0 0.3 1.7 8.6 0.2 1.4 3.6 0.3 0.9 2.8 7.4 0.0 0.2 4.0 0.0 0.2 2.4 2.2 0.3 11.8 1.5 13.4 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.1 0.0 7.1 0.0 1.1 0.0 0.1 0.0 0.2 0.0 1.6 0.6 0.0 1.8 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 3.6 0.0 0.7 0.5 0.8 0.2 4.6 3.7 3.0 0.8 1.2 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 18.4 1.6 13.8 7.1 3.9 4.7 2.6 4.9 0.4 8.6 7.4 29.5 0.0 0.5 20.2 0.5 1.7 2.2 0.0 1.2 24.0 0.4 0.9 5.1 0.0 0.0 3.7 12.5 0.1 0.0 0.1 0.0 5.8 2.5 0.9 24.2 12.5 0.0 2.7 353.8 0.2 0.0 8.2 0.0 1.1 0.0 42.7 2.2 0.2 0.4 18.5 141.8 0.0 0.0 0.8 1.5 6.5 24.5 1.1 3.6 18.7 0.0 29.3 0.0 208.6 10.7 0.3 0.0 25.2 1.2 2.4 0.0 0.1 0.0 4.8 105.2 20.7 107.0 1.6 1.5 0.7 1.1 0.3 0.5 19.6 0.0 1.5 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 156.3" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Enteroendocrine cells: 20.4;Granulosa cells: 10.2;Hepatocytes: 20.2" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.1;CACO-2: 30.4;Hep G2: 32.6;NTERA-2: 38.4;SK-MEL-30: 87.6;SuSa: 59.0" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: AB_2685323" "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favorable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 156.3 2.2 10.3 1.9 10.8 0.2 38.9 18.4 8.8 3.0 8.5 3.9 1.5 6.6 1.0 0.9 5.1 2.2 1.4 11.2 18.9 2.0 18.5 0.5 0.6 29.4 24.5 2.5 5.4 1.0 0.8 2.1 27.3 4.0 2.8 1.4 4.7 6.6 0.3 1.9 2.1 3.7 36.0 0.3 4.5 0.9 13.7 0.4 1.7 0.5 0.3 3.7 2.0 35.4 0.1 11.5 39.1 0.2 20.5 0.0 28.5 2.0 6.3 6.1 8.2 30.4 0.6 0.0 3.1 5.2 6.6 0.0 22.5 0.5 6.8 0.2 6.3 0.1 0.7 32.6 6.7 0.0 8.9 8.1 0.4 1.0 0.0 0.2 0.0 0.0 0.3 0.1 6.6 1.9 0.0 1.0 38.4 0.4 0.2 6.1 13.0 0.0 0.0 0.1 0.0 0.7 0.1 0.3 87.6 59.0 4.1 25.4 0.0 0.0 6.7 3.8 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.3 10.8 18.4 8.8 11.2 18.9 29.4 24.5 27.3 36.0 13.7 35.4 0.3 0.0 0.0 10.7 0.2 0.4 1.1 0.5 0.0 1.2 2.1 0.8 1.2 4.3 0.2 0.0 4.2 6.0 0.0 1.2 5.9 1.0 0.4 3.8 1.0 0.3 20.4 0.0 5.9 4.0 7.9 1.6 4.6 0.7 0.0 10.2 0.0 20.2 1.1 0.0 4.9 1.7 0.0 1.0 0.0 0.5 0.6 0.1 3.6 0.0 0.0 1.6 0.0 0.5 0.1 2.1 0.6 3.0 0.0 1.0 0.4 2.4 1.1 0.1 0.0 0.3 1.2 0.3 1.5 0.0 0.3 2.3 0.0 3.2 3.5 0.7 GYS1 "GSY, GYS" ENSG00000104812 "Glycogen synthase 1" P13807 19 48968130-48993310 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 118.5;skeletal muscle: 319.4;tongue: 201.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007793, HPA041598" Enhanced Approved Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "CAB007793: AB_562291, HPA041598: AB_2677571" "unprognostic (3.37e-1)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (6.83e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (3.30e-2)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.46e-4)" "unprognostic (4.04e-2)" "unprognostic (6.76e-2)" "unprognostic (5.87e-3)" "unprognostic (3.81e-2)" 32.4 26.3 17.9 16.2 18.8 46.0 23.7 26.4 23.3 17.1 22.2 21.7 15.3 18.8 8.9 38.2 18.7 10.1 118.5 19.7 17.6 21.8 14.9 16.0 15.5 22.2 20.9 19.7 13.6 15.7 15.5 11.3 19.6 27.4 14.7 19.2 22.2 15.5 319.4 20.7 19.9 16.7 16.4 18.5 23.2 6.1 20.2 14.7 15.9 201.6 14.4 24.3 23.2 18.3 67.3 26.3 19.0 26.3 43.2 16.9 37.6 45.5 31.7 46.8 54.3 25.8 21.3 28.0 27.0 44.7 12.4 46.6 32.0 57.7 40.6 17.4 46.5 23.1 33.3 23.1 24.3 25.4 15.9 41.8 27.2 30.2 25.4 40.5 39.8 28.8 16.4 36.1 59.4 25.4 31.8 21.9 10.2 29.0 29.8 26.6 33.2 27.5 46.7 70.6 11.8 16.4 40.5 52.1 10.4 25.2 27.7 26.1 31.0 57.1 22.0 26.1 50.5 29.8 33.1 13.5 58.3 22.2 13.1 7.7 9.4 6.6 7.0 5.3 8.6 5.2 6.0 6.5 13.4 3.9 4.7 4.4 3.7 10.6 8.0 7.2 8.6 7.1 17.9 18.8 26.4 23.3 19.7 17.6 22.2 20.9 19.6 16.4 20.2 18.3 3.5 0.0 14.2 21.9 5.9 5.1 3.7 11.7 11.4 4.2 7.3 5.5 67.9 2.8 5.8 0.0 16.7 7.6 6.8 13.2 0.0 8.1 0.3 6.9 8.9 7.1 7.2 4.8 14.7 6.9 31.7 5.0 12.8 11.9 4.5 6.7 9.7 5.2 8.3 0.0 16.6 9.2 4.1 7.0 5.7 0.7 5.3 7.2 7.2 4.7 9.8 3.3 10.3 8.5 6.9 11.8 8.2 5.7 9.7 5.4 9.2 6.0 6.2 11.7 0.0 5.0 7.3 1.3 2.9 15.3 4.1 4.0 5.2 3.8 11.7 3.3 GYS2 ENSG00000111713 "Glycogen synthase 2" P54840 12 21536107-21604847 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "liver: 173.8" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 63.6" "Cancer enriched" "Detected in single" 29 "liver cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039482 Approved NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "HPA039482: AB_10795107" "unprognostic (7.22e-3)" "unprognostic (2.85e-2)" "unprognostic (8.88e-2)" "unprognostic (1.78e-2)" "unprognostic (5.68e-2)" "unprognostic (3.16e-1)" "prognostic favorable (7.62e-5)" "unprognostic (1.06e-1)" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (4.68e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (4.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.85e-1)" "unprognostic (2.66e-4)" 3.1 0.0 0.1 0.0 0.0 0.0 1.0 0.1 0.1 2.4 0.0 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.2 0.0 0.0 0.2 173.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.4 63.6 0.0 0.0 7.7 0.0 6.1 1.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 5.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.1" "Group enriched" "Detected in many" 24 "dendritic cells: 739.3;NK-cells: 1543.8;T-cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 15 "gdT-cell: 941.4;MAIT T-cell: 926.2;memory CD4 T-cell: 250.0;memory CD8 T-cell: 922.7;naive CD8 T-cell: 494.1;NK-cell: 718.8" "Group enriched" "Detected in all" 42 "NK-cells: 718.8;T-cells: 941.4" "Cell line enhanced" "Detected in some" "HL-60: 4.0;JURKAT: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054134, HPA076751" Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 5.6 6.0 0.9 16.7 0.9 35.3 7.2 0.9 2.5 7.6 1.2 14.7 29.2 14.7 8.8 4.8 4.6 14.0 4.0 0.8 1.0 3.2 15.2 21.9 68.1 1.6 0.9 4.5 1.0 1.3 1.0 3.1 1.1 3.1 17.8 0.0 7.1 3.0 1.7 1.6 27.6 7.2 1.1 51.1 11.7 2.0 1.1 12.4 2.9 1.3 19.2 13.5 2.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 2.5 3.8 941.4 2.3 926.2 3.4 250.0 922.7 3.1 1.3 48.5 494.1 19.9 718.8 4.0 3.2 33.1 712.7 0.9 0.9 0.9 2.5 0.8 1.0 1.6 0.9 1.1 1.1 1.1 1.1 5.1 3.2 18.1 0.0 12.3 0.4 0.1 0.0 2.8 0.0 2.7 2.4 1.6 5.7 3.1 0.0 0.0 0.4 739.3 1.4 0.0 1.6 0.0 1.7 2.7 2.8 0.0 36.2 0.0 0.0 0.2 7.8 20.4 2.1 7.6 0.0 17.9 2.8 0.3 0.0 0.1 1.5 0.0 25.8 2.6 0.0 0.0 12.3 3.6 0.0 12.6 0.0 1543.8 0.0 0.1 0.0 3.9 0.0 40.8 0.1 2.8 3.3 2.9 0.0 0.0 2.6 2.6 0.0 0.1 1.1 1.4 0.7 709.4 0.0 1.8 0.0 GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.9;lymphoid tissue: 25.2" "Group enriched" "Detected in many" 10 "dendritic cells: 575.2;NK-cells: 492.3;T-cells: 302.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 1678.5;memory CD4 T-cell: 490.7;memory CD8 T-cell: 1389.6;naive CD8 T-cell: 1214.0" "Lineage enriched" "Detected in all" 7 "T-cells: 1678.5" "Cell line enhanced" "Detected in single" "U-266/70: 1.0" "Low region specificity" "Detected in many" HPA029200 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favorable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" 3.4 5.2 1.2 3.1 1.3 33.9 4.6 1.3 2.4 2.6 1.6 2.7 2.4 2.0 5.0 3.6 3.5 7.0 2.5 1.1 1.3 1.2 6.7 15.9 25.2 2.0 1.2 2.8 0.8 0.7 2.4 1.6 1.5 1.4 2.5 0.0 7.9 2.1 1.9 0.6 2.8 3.4 1.3 24.4 4.7 0.8 1.4 3.8 1.5 0.6 4.5 7.5 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.2 31.6 3.4 1.7 1678.5 3.6 30.2 7.6 490.7 1389.6 3.3 4.6 155.1 1214.0 18.6 250.8 5.4 44.6 4.5 1436.5 1.2 1.3 1.3 2.4 1.1 1.3 2.0 1.2 1.5 1.3 1.4 1.3 2.9 0.0 4.6 0.0 3.3 1.1 0.1 0.0 0.0 0.0 1.7 1.5 1.4 8.6 0.0 0.0 0.0 0.1 575.2 0.0 0.0 0.1 0.1 0.3 0.3 1.5 0.0 8.6 0.0 0.0 0.0 1.2 1.1 0.4 1.3 0.0 7.5 1.2 0.1 0.0 0.0 0.0 0.0 9.3 3.4 0.2 0.0 4.5 3.6 1.9 3.1 0.0 492.3 0.0 0.1 0.0 0.0 0.0 43.7 0.2 0.0 2.6 0.7 0.0 0.0 1.9 1.3 0.1 0.0 0.4 1.8 0.0 302.2 0.0 0.1 0.1 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 4 "dendritic cells: 136.3;T-cells: 301.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Cell line enriched" "Detected in single" 10 "JURKAT: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.0 3.9 0.1 19.4 0.1 10.5 4.9 0.1 0.4 4.3 0.3 3.4 1.6 4.0 4.5 3.0 2.0 11.6 2.0 0.1 0.2 1.7 10.7 5.9 99.6 0.5 0.2 2.7 1.0 0.8 0.5 0.5 0.3 3.2 4.6 0.0 4.6 1.0 0.2 0.6 7.3 2.2 0.2 30.4 6.5 1.2 0.3 11.9 2.3 0.3 27.8 8.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 1.1 164.3 1.0 741.6 0.5 100.2 457.3 0.5 0.5 4.9 77.4 3.1 505.5 0.9 0.9 7.0 95.5 0.1 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.3 0.2 0.3 0.3 3.8 3.2 7.0 0.0 10.7 1.5 0.1 0.0 1.8 0.0 1.5 1.7 0.1 2.8 0.6 0.0 0.0 0.0 136.3 0.1 0.0 0.0 1.3 0.8 0.4 0.8 0.0 4.4 0.0 0.0 0.0 1.2 4.1 0.8 2.5 0.0 8.6 1.5 0.2 0.0 0.0 0.0 0.0 10.3 2.5 1.2 0.0 6.4 1.8 0.0 5.1 0.0 29.9 0.0 0.1 0.0 0.0 0.0 45.1 0.1 0.2 0.8 0.0 0.0 0.0 1.8 1.7 0.0 0.3 0.2 0.6 0.3 301.9 0.0 0.0 0.1 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 13 "dendritic cells: 385.8;NK-cells: 810.5;T-cells: 243.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.7;HMC-1: 2.1;JURKAT: 3.5;MOLT-4: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 2.2 1.1 0.9 10.0 0.9 21.6 1.1 3.6 2.0 1.4 0.3 1.5 2.1 0.8 0.2 0.8 1.3 1.8 0.8 0.9 0.9 1.0 3.3 5.3 19.2 1.0 0.8 0.7 0.4 0.0 0.9 0.4 1.0 1.3 0.3 0.2 2.8 0.4 0.7 0.8 6.2 0.2 0.7 22.7 3.7 1.8 0.9 8.7 1.6 0.1 3.8 1.5 1.4 1.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.1 0.0 0.4 1.3 0.6 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.1 0.5 0.1 0.3 0.1 9.1 1.4 1.3 583.9 1.7 366.5 0.9 189.2 471.3 1.5 4.0 182.8 379.2 11.9 194.9 2.3 3.6 99.1 227.5 0.9 0.9 3.6 2.0 0.9 0.9 1.0 0.8 1.0 0.7 0.9 1.0 3.4 0.0 0.0 0.3 5.7 3.1 0.1 0.0 0.6 0.5 2.4 2.2 0.1 1.5 0.0 0.0 0.0 0.2 385.8 0.1 0.0 0.4 0.9 0.6 1.5 1.4 0.0 12.0 0.3 0.4 0.4 2.2 13.3 1.1 0.0 0.1 3.6 1.4 0.2 0.0 0.2 0.4 0.0 3.7 4.7 1.6 0.0 5.9 1.8 1.0 8.6 1.6 810.5 0.5 0.3 0.3 0.0 0.0 35.8 0.1 0.0 1.2 0.0 1.4 0.0 1.5 1.2 0.5 1.1 0.9 1.4 0.5 243.6 0.2 0.1 0.1 H1-3 "H1.3, H1d, H1F3, H1s-2, HIST1H1D" ENSG00000124575 "H1.3 linker histone, cluster member" P16402 6 26234212-26234987 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 21.1;brain: 24.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.4;dendritic cells: 23.3;Extravillous trophoblasts: 18.3;Hofbauer cells: 7.5;Plasma cells: 7.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 24.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "BEWO: 5.8;MOLT-4: 9.9;NB-4: 4.3;REH: 4.0;SiHa: 3.8;U-266/70: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA055907 Supported NA NA 4000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA055907: AB_2682966" "unprognostic (8.78e-2)" "unprognostic (1.01e-4)" "unprognostic (8.69e-2)" "unprognostic (5.67e-2)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.11e-2)" "unprognostic (2.13e-1)" "unprognostic (3.06e-2)" "unprognostic (1.99e-1)" "unprognostic (1.14e-2)" "unprognostic (8.96e-2)" "unprognostic (3.61e-8)" "unprognostic (8.78e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-2)" 1.2 0.1 1.3 0.2 0.5 21.1 1.1 24.1 4.6 1.7 3.4 1.5 0.0 0.1 0.1 0.7 0.4 0.0 0.4 0.5 1.4 0.6 0.3 1.3 1.9 2.5 1.8 0.3 0.0 0.0 0.1 0.5 4.5 1.4 0.7 0.0 0.5 0.0 0.0 2.4 2.5 0.1 3.8 1.3 0.6 0.3 2.6 5.5 0.5 0.0 0.4 0.2 3.8 7.0 0.7 0.5 0.1 0.0 0.2 0.0 5.8 0.3 0.2 0.7 0.5 0.1 0.6 0.0 0.1 0.1 0.3 0.7 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.2 0.8 1.7 1.7 0.1 0.0 9.9 4.3 0.5 0.0 1.7 4.0 0.1 2.2 0.0 0.0 1.9 0.3 3.8 1.6 0.0 0.5 0.7 0.9 0.0 0.2 0.0 0.1 0.6 4.8 2.5 0.3 0.6 1.2 0.5 22.3 7.5 6.5 31.4 4.4 21.9 32.1 28.7 21.7 18.2 46.7 37.1 30.6 2.6 25.8 6.9 32.8 23.4 14.1 1.3 0.5 24.1 4.6 0.5 1.4 2.5 1.8 4.5 3.8 2.6 7.0 3.5 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 4.4 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 18.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 3.6 3.6 0.0 0.0 0.0 H2AC7 "H2A.3, H2A/g, H2AFG, HIST1H2AD" ENSG00000196866 "H2A clustered histone 7" P20671 6 26198784-26199293 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 17.5;U-266/84: 6.3" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (5.03e-2)" "unprognostic (1.11e-2)" "unprognostic (7.27e-2)" "unprognostic (3.56e-1)" "unprognostic (9.17e-2)" "unprognostic (1.45e-1)" "unprognostic (9.09e-3)" "unprognostic (6.72e-2)" "unprognostic (1.92e-1)" "unprognostic (4.34e-1)" "unprognostic (1.81e-1)" "unprognostic (2.88e-2)" "unprognostic (1.10e-9)" "unprognostic (2.00e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" 0.7 0.2 0.4 0.3 1.7 2.9 0.6 4.1 2.1 3.3 3.6 0.5 0.0 0.1 0.0 2.5 0.6 0.3 0.4 1.0 1.9 0.6 1.2 2.1 0.5 3.1 1.7 0.7 0.1 0.0 0.3 0.2 2.1 2.1 0.1 0.0 0.5 0.0 0.0 1.1 0.5 0.0 3.9 1.2 0.6 0.3 3.0 1.8 0.3 0.0 0.3 0.3 2.8 6.8 1.1 0.0 0.2 0.2 0.0 0.0 0.2 0.7 0.1 1.1 0.0 1.3 0.4 0.7 1.2 0.2 0.1 0.3 0.0 0.1 0.2 0.0 1.0 0.3 1.4 1.3 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.7 2.5 1.3 0.0 0.0 3.7 1.5 1.1 0.0 1.1 1.0 0.4 0.9 0.4 0.1 1.4 0.2 0.6 0.8 0.1 0.0 1.4 0.3 0.0 1.1 3.1 0.0 1.0 17.5 6.3 2.2 1.0 1.3 0.4 2.3 0.3 3.8 1.3 1.9 1.3 2.7 2.0 4.0 1.1 7.6 1.9 1.9 17.9 1.8 2.2 6.2 2.7 0.8 0.4 1.7 4.1 2.1 1.0 1.9 3.1 1.7 2.1 3.9 3.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H2AJ "FLJ10903, H2AFJ, MGC921" ENSG00000246705 "H2A.J histone" Q9BTM1 12 14774383-14778002 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 565.0" "Cell type enhanced" "Detected in some" "Adipocytes: 58.1;Cytotrophoblasts: 130.2;dendritic cells: 56.4;Extravillous trophoblasts: 124.3;Fibroblasts: 59.5;Hofbauer cells: 241.2;Syncytiotrophoblasts: 160.3" "Cancer enhanced" "Detected in all" "prostate cancer: 151.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 256.2;MCF7: 338.4;RT4: 239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (9.38e-2)" "unprognostic (8.49e-2)" "unprognostic (9.15e-2)" "unprognostic (7.06e-2)" "unprognostic (2.43e-3)" "unprognostic (4.70e-2)" "unprognostic (3.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (4.05e-2)" "unprognostic (3.32e-3)" "unprognostic (3.43e-2)" "unprognostic (8.66e-3)" "unprognostic (5.22e-3)" "unprognostic (3.87e-3)" 236.7 186.0 29.1 33.8 34.1 60.4 223.6 33.7 40.9 123.7 37.9 126.6 55.4 105.6 20.9 155.7 106.6 36.0 125.5 27.7 31.3 115.7 82.7 129.6 29.6 37.1 32.5 63.6 182.3 21.1 34.2 57.7 35.7 275.8 29.3 5.3 166.8 35.0 91.4 198.4 85.2 25.1 33.4 94.8 111.1 565.0 33.1 34.2 85.0 24.8 18.2 122.8 124.9 38.7 107.9 256.2 10.0 0.0 112.2 73.8 163.2 78.9 43.4 31.3 30.4 50.9 172.4 0.1 48.7 38.6 0.2 100.7 6.2 60.1 8.5 5.7 4.6 4.3 92.6 43.8 160.5 0.1 39.0 97.0 64.5 43.3 40.0 12.7 63.0 0.0 0.1 0.1 15.9 338.4 0.7 28.7 16.0 77.8 58.0 42.4 0.0 21.0 51.0 239.0 3.0 1.0 99.8 122.3 0.4 34.6 187.0 32.6 63.1 0.3 29.6 46.2 15.6 25.0 39.4 0.4 8.6 0.3 25.4 84.0 127.6 29.3 51.3 76.4 46.3 16.8 49.6 38.0 117.2 21.7 34.9 38.2 46.6 61.2 69.4 58.2 78.1 72.1 29.1 34.1 33.7 40.9 27.7 31.3 37.1 32.5 35.7 33.4 33.1 38.7 58.1 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 130.2 56.4 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 124.3 59.5 0.0 0.0 0.0 0.0 0.0 0.0 241.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.0 0.0 160.3 6.5 0.0 0.0 0.0 H2BC7 "H2B/g, H2BFG, HIST1H2BF" ENSG00000277224 "H2B clustered histone 7" P62807 6 26199520-26200715 "Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 7.4" "Cell type enhanced" "Detected in single" "Hofbauer cells: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "U-266/70: 24.8;U-266/84: 18.8" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.15e-2)" "unprognostic (2.17e-1)" "unprognostic (1.12e-1)" "unprognostic (1.38e-2)" "unprognostic (4.58e-2)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" "unprognostic (6.80e-3)" "unprognostic (3.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.95e-1)" "unprognostic (7.27e-3)" "unprognostic (4.29e-11)" "unprognostic (4.88e-3)" "unprognostic (4.45e-1)" "unprognostic (1.15e-2)" "unprognostic (1.30e-1)" 0.9 0.2 0.6 0.2 1.1 1.2 1.6 4.0 0.9 3.3 1.5 1.4 0.0 0.1 0.0 3.2 1.8 0.2 0.4 0.8 0.6 1.4 0.6 1.7 0.3 1.9 1.7 0.8 0.2 0.0 0.6 0.2 2.4 7.4 0.2 0.6 1.1 0.0 0.0 0.9 0.7 0.0 2.1 2.3 0.7 0.6 1.2 1.7 0.6 0.1 0.4 0.4 4.5 2.4 0.5 0.3 0.2 0.5 0.3 0.0 0.2 0.2 0.1 0.7 0.1 0.7 0.1 0.6 1.0 0.0 0.3 1.0 0.5 0.1 0.3 0.8 0.2 0.4 1.8 0.2 0.1 0.1 0.9 0.3 0.1 0.2 0.1 0.0 0.1 0.5 2.0 4.5 0.0 0.1 4.0 1.6 0.6 0.8 0.6 1.5 0.7 3.0 0.1 0.1 2.4 0.4 4.9 0.9 0.1 0.3 4.4 0.2 0.1 0.3 2.2 0.0 0.6 24.8 18.8 1.3 0.1 1.2 0.5 0.0 0.0 0.6 0.2 0.1 0.6 0.2 0.2 0.3 0.1 1.0 0.2 0.5 2.4 0.2 0.3 0.3 0.2 0.5 0.6 1.1 4.0 0.9 0.8 0.6 1.9 1.7 2.4 2.1 1.2 2.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 H3C4 "H3/b, H3FB, HIST1H3D" ENSG00000197409 "H3 clustered histone 4" P68431 6 26196784-26197286 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.2;brain: 15.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 5.7;MOLT-4: 5.4;U-266/70: 11.7;U-266/84: 6.9" HPA042570 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA042570: AB_2678056" "unprognostic (8.64e-2)" "unprognostic (1.27e-2)" "unprognostic (9.06e-3)" "unprognostic (2.00e-1)" "unprognostic (6.59e-2)" "unprognostic (1.43e-2)" "unprognostic (8.62e-2)" "unprognostic (1.56e-1)" "unprognostic (2.95e-1)" "unprognostic (2.69e-2)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.78e-6)" "unprognostic (2.44e-1)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (4.94e-2)" 0.6 0.8 4.3 0.1 4.1 12.2 0.6 15.9 3.2 2.3 5.7 1.0 0.6 0.2 0.0 2.0 0.9 0.5 0.5 1.1 2.6 0.9 1.5 1.4 0.4 4.8 5.2 0.8 0.2 0.0 0.6 0.2 4.8 2.8 0.0 0.1 1.0 0.1 0.0 0.7 0.7 0.1 6.7 1.7 0.6 0.8 4.5 1.8 0.6 0.0 0.3 0.7 2.8 10.9 1.5 0.0 0.2 1.2 0.8 0.3 0.7 0.0 0.3 1.6 1.1 2.9 0.6 2.7 1.3 0.4 0.0 0.4 0.7 0.1 0.0 1.5 0.2 0.1 1.3 2.0 0.1 0.9 1.8 0.1 0.1 1.2 0.3 0.0 0.5 1.1 1.2 5.7 0.0 0.6 5.4 4.6 0.2 0.1 0.9 2.7 0.3 3.1 0.0 0.0 0.8 0.1 0.0 1.0 0.8 0.0 0.6 1.6 1.4 0.3 2.9 0.0 1.5 11.7 6.9 0.6 1.5 0.3 0.4 14.8 1.6 4.2 3.4 1.6 8.6 8.3 2.5 3.5 3.9 13.0 2.6 4.6 22.2 3.2 3.5 5.1 3.3 0.9 4.3 4.1 15.9 3.2 1.1 2.6 4.8 5.2 4.8 6.7 4.5 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H4C5 "H4/j, H4FJ, HIST1H4E" ENSG00000276966 "H4 clustered histone 5" P62805 6 26204552-26206038 "Disease related genes, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 69.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 1.2;Cytotrophoblasts: 2.7;dendritic cells: 1.8;Extravillous trophoblasts: 1.6;Hofbauer cells: 4.6;Plasma cells: 1.3;Syncytiotrophoblasts: 3.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 69.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 6.1;U-266/70: 11.3" HPA042201 Supported NA NA 25000000 "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA042201: AB_2677898" "unprognostic (8.62e-2)" "unprognostic (4.86e-2)" "unprognostic (5.71e-3)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" "unprognostic (5.08e-3)" "unprognostic (7.99e-2)" "unprognostic (1.21e-1)" "unprognostic (6.57e-2)" "unprognostic (2.34e-3)" "unprognostic (4.34e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (1.28e-2)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" 0.8 0.5 12.1 0.4 14.5 2.1 0.8 69.4 14.4 3.8 0.5 1.9 0.9 0.5 0.8 2.6 2.7 0.2 1.1 10.8 8.1 3.1 1.0 1.0 0.5 3.9 3.2 2.8 0.5 0.2 2.2 0.5 6.9 7.5 0.5 1.5 1.3 0.3 0.0 1.9 0.9 0.2 15.2 1.5 1.6 2.0 7.2 1.9 1.5 0.0 0.4 0.6 3.6 16.8 1.1 0.7 1.3 3.1 0.5 0.0 0.7 1.1 0.3 0.5 0.4 0.4 1.1 0.4 1.5 0.3 0.7 1.9 0.7 0.1 0.7 0.9 0.8 0.3 1.5 0.7 0.0 0.5 1.2 0.3 0.0 0.4 0.3 0.3 0.4 1.0 2.3 2.6 0.1 0.4 6.1 2.8 1.3 0.5 1.0 2.7 1.4 2.7 0.5 0.4 3.7 0.9 0.8 1.3 0.4 0.4 1.2 0.5 0.5 1.5 2.1 0.4 0.9 11.3 4.7 1.7 0.3 1.1 1.1 2.7 2.1 1.8 2.0 1.8 2.9 2.5 3.0 2.0 3.1 5.4 3.2 2.6 2.6 2.3 5.5 2.7 2.0 1.2 12.1 14.5 69.4 14.4 10.8 8.1 3.9 3.2 6.9 15.2 7.2 16.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 HACD1 "CAP, PTPLA" ENSG00000165996 "3-hydroxyacyl-CoA dehydratase 1" B0YJ81 10 17589032-17617374 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Developmental protein, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.0" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 143.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "T-reg: 55.7" "Lineage enriched" "Detected in many" 12 "T-cells: 55.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (3.54e-1)" "unprognostic (2.62e-2)" "unprognostic (4.10e-1)" "unprognostic (5.67e-3)" "unprognostic (4.21e-2)" "unprognostic (3.04e-2)" "unprognostic (2.38e-1)" "unprognostic (1.70e-2)" "unprognostic (2.61e-2)" "unprognostic (3.43e-1)" "unprognostic (2.46e-2)" "unprognostic (2.93e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (6.49e-2)" 9.7 7.0 3.1 5.0 3.5 8.0 8.8 10.7 4.6 6.8 2.9 31.9 2.8 22.1 3.3 7.8 10.3 3.6 73.0 3.0 6.5 5.0 1.6 9.7 1.3 5.5 5.2 4.3 2.7 0.5 3.7 1.6 5.0 11.9 3.8 2.3 2.7 16.7 36.5 3.0 6.9 25.4 2.4 1.7 15.0 3.5 4.7 2.6 7.6 16.5 1.2 18.1 6.8 8.4 29.3 24.6 6.8 33.4 30.1 5.8 0.6 40.5 24.4 51.9 48.5 16.4 34.6 0.2 5.9 66.4 74.5 7.1 17.3 12.3 28.6 19.1 10.4 67.1 18.4 45.6 39.0 0.3 4.8 14.0 17.2 29.9 11.6 39.8 10.1 35.1 0.6 1.3 69.0 21.0 50.4 6.7 14.6 2.2 6.6 44.7 7.1 0.8 20.5 5.6 7.5 19.1 34.6 0.6 58.9 21.2 24.2 16.7 9.8 30.3 17.4 18.7 18.8 0.9 0.8 0.3 22.3 7.7 4.3 4.7 0.9 0.7 1.2 0.1 0.3 0.4 5.0 1.0 3.0 1.3 0.9 0.7 2.6 3.3 0.3 1.5 55.7 1.3 3.1 3.5 10.7 4.6 3.0 6.5 5.5 5.2 5.0 2.4 4.7 8.4 2.4 28.9 15.0 0.3 0.4 0.0 23.1 0.0 8.0 0.8 6.9 21.6 143.7 10.0 2.5 31.3 0.0 0.5 4.4 0.4 3.9 16.5 11.1 5.6 8.0 5.4 3.6 29.2 10.4 8.0 1.9 7.1 8.2 12.4 6.3 17.5 20.7 1.0 5.4 0.0 11.7 2.5 0.0 2.2 0.0 2.7 1.8 3.6 0.0 5.6 0.8 0.5 1.0 2.5 31.8 15.6 0.8 0.7 0.6 23.9 0.5 2.3 0.7 0.6 0.0 5.7 32.5 7.4 5.2 17.7 0.0 3.0 2.9 10.8 3.5 6.2 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827157 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 378.7;Proximal tubular cells: 501.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved NA NA 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA043041: AB_2678284, HPA061143: AB_2684439" "unprognostic (3.11e-1)" "prognostic favorable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favorable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favorable (5.19e-4)" 41.2 109.0 81.5 20.2 84.2 82.1 35.1 82.7 103.9 22.8 78.9 53.7 45.3 24.6 31.1 29.0 28.5 21.9 138.6 89.9 83.8 100.1 236.2 39.2 24.6 82.8 80.2 22.0 63.5 54.0 72.7 23.1 83.7 33.5 23.3 32.2 32.5 37.7 198.8 31.2 44.8 24.7 80.1 35.2 52.9 91.7 84.0 35.8 35.1 156.2 18.4 34.8 24.6 87.6 31.1 46.1 40.9 46.5 35.1 13.8 37.0 38.1 35.2 57.7 46.1 23.7 26.5 6.4 76.5 32.9 39.6 33.2 39.1 38.2 17.2 64.5 63.4 12.0 47.9 69.3 50.2 15.7 62.6 16.9 80.6 28.8 19.6 50.6 50.1 79.8 16.1 56.3 18.3 51.2 41.1 34.0 15.7 32.0 42.3 34.2 25.8 73.6 74.5 13.8 54.7 47.4 41.8 52.9 84.9 30.8 38.7 52.0 38.7 17.5 21.5 36.9 44.6 63.3 64.7 19.8 29.8 14.5 28.5 37.3 33.3 64.9 26.0 59.1 19.0 31.3 34.0 27.3 30.7 30.4 32.0 27.4 29.7 25.5 88.2 64.8 42.8 30.3 81.5 84.2 82.7 103.9 89.9 83.8 82.8 80.2 83.7 80.1 84.0 87.6 46.2 9.6 39.0 11.8 33.7 23.8 45.1 59.7 12.0 117.1 39.5 31.1 84.2 65.8 39.7 46.0 64.6 52.4 43.2 60.9 158.5 45.6 193.1 75.0 12.1 35.3 39.6 378.7 24.6 38.3 38.5 25.6 23.9 35.5 30.4 36.0 41.0 186.9 76.2 138.0 22.2 41.2 93.6 49.0 41.6 60.1 46.9 47.6 55.2 12.2 50.1 95.2 64.9 7.1 19.7 49.7 68.8 54.9 50.4 48.3 168.9 501.7 70.2 117.0 72.3 33.3 61.1 245.2 68.3 29.1 45.6 68.7 44.1 45.3 39.9 49.9 HAND2 "bHLHa26, dHand, Hed, Thing2" ENSG00000164107 "Heart and neural crest derivatives expressed 2" P61296 4 173524969-173530229 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 60.5" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 100.3;Endometrial stromal cells: 317.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.5;stomach cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "SH-SY5Y: 410.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019591, CAB025576" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Vesicles "CAB025576: , HPA019591: AB_2670199" "unprognostic (4.11e-2)" "unprognostic (7.50e-3)" "unprognostic (2.43e-2)" "unprognostic (1.25e-2)" "unprognostic (1.95e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "unprognostic (2.24e-1)" "unprognostic (1.28e-2)" "unprognostic (2.56e-1)" "unprognostic (2.44e-1)" "unprognostic (1.35e-1)" "unprognostic (3.27e-2)" "unprognostic (4.95e-2)" "unprognostic (1.56e-1)" "unprognostic (6.39e-3)" 4.9 28.0 0.0 5.4 0.0 0.0 2.1 0.5 0.0 22.2 0.0 60.5 2.5 33.4 0.3 1.0 16.0 16.2 36.8 0.0 0.0 0.1 5.5 0.0 0.2 0.0 0.0 15.3 4.1 0.0 0.1 20.9 0.2 1.3 4.4 0.0 0.8 1.0 0.2 1.5 11.0 27.3 0.0 1.1 22.1 0.4 0.0 0.4 1.5 1.1 0.8 12.4 5.3 0.0 0.0 0.1 0.0 0.0 16.6 7.7 0.3 2.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.3 0.0 0.1 1.7 0.0 3.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 410.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 1.3 4.1 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.2 0.0 0.1 0.1 100.3 2.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.6 0.2 9.0 317.1 2.7 0.0 0.0 0.0 0.4 1.4 30.4 0.0 5.3 0.0 0.0 6.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 2.3 0.9 39.4 1.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 10.9 0.1 0.3 0.2 0.3 2.3 1.3 0.6 0.0 0.0 HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105653-69118719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.5;urinary bladder: 92.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 162.3;Basal prostatic cells: 51.6;Basal respiratory cells: 107.1;Suprabasal keratinocytes: 158.6;Urothelial cells: 115.5" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 52.5;PC-3: 270.5;RT4: 111.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA031554, CAB033850" Supported Approved Microtubules NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" 0.8 0.5 0.9 0.7 1.2 0.9 7.5 1.3 1.3 4.6 0.9 5.3 2.9 0.9 1.1 33.5 1.2 4.8 0.7 0.6 1.1 1.1 1.3 20.1 0.4 1.0 1.3 1.4 1.3 0.4 1.7 3.4 1.1 3.7 3.1 0.8 5.4 1.5 1.2 9.7 2.2 0.6 0.4 0.8 12.8 3.5 1.0 0.5 5.9 0.9 2.8 92.8 10.3 1.0 3.5 17.1 1.0 0.9 0.3 0.4 6.6 1.1 0.4 1.0 0.4 3.4 9.0 0.7 2.0 0.4 4.0 52.5 2.9 31.5 1.0 0.2 1.3 0.0 0.2 0.6 0.1 0.3 0.9 0.5 8.6 1.0 3.0 4.0 0.7 0.6 0.1 0.4 0.3 1.8 1.2 0.7 15.5 18.7 270.5 2.0 0.1 0.2 28.3 111.6 19.2 0.8 1.8 0.1 0.3 3.1 0.6 0.8 0.3 0.9 0.9 29.9 1.8 1.0 0.9 0.2 1.0 0.0 0.6 0.1 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.9 1.2 1.3 1.3 0.6 1.1 1.0 1.3 1.1 0.4 1.0 1.0 4.2 0.0 30.8 0.7 0.2 162.3 51.6 107.1 8.6 1.1 1.6 6.1 1.4 0.0 12.2 0.0 2.1 1.0 0.1 16.4 0.0 4.5 10.2 0.7 0.3 2.4 0.0 0.4 1.0 3.6 0.9 1.1 5.1 2.7 0.0 0.4 1.1 0.2 0.3 0.0 2.1 0.7 2.0 0.0 6.5 22.7 1.2 0.5 3.6 0.0 0.0 0.1 0.0 0.5 0.8 2.4 0.2 0.4 0.6 18.4 0.1 0.7 3.0 1.0 0.0 0.9 1.9 0.5 0.7 25.6 158.6 0.3 1.1 0.1 2.2 115.5 HAVCR2 "CD366, FLJ14428, Tim-3, TIM3, TIMD3" ENSG00000135077 "Hepatitis A virus cellular receptor 2" Q8TDQ0 5 157085832-157142869 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.1" "Cell type enhanced" "Detected in many" "dendritic cells: 87.6;granulocytes: 80.6;Hofbauer cells: 148.3;Kupffer cells: 89.1;Langerhans cells: 67.8;Macrophages: 83.2;monocytes: 49.5;NK-cells: 70.0;Proximal tubular cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 53.8;intermediate monocyte: 57.9;myeloid DC: 137.9;NK-cell: 97.1;non-classical monocyte: 36.1" "Group enriched" "Detected in all" 6 "dendritic cells: 137.9;monocytes: 57.9;NK-cells: 97.1" "Cell line enhanced" "Detected in some" "ASC diff: 7.8;Daudi: 6.4;HDLM-2: 26.3;HMC-1: 6.0;RPMI-8226: 21.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB026003 Enhanced NA NA 9900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026003: " "unprognostic (2.50e-2)" "unprognostic (1.11e-2)" "unprognostic (5.18e-2)" "unprognostic (2.04e-3)" "unprognostic (3.79e-2)" "unprognostic (1.14e-1)" "unprognostic (6.69e-2)" "unprognostic (2.54e-1)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (8.48e-2)" "unprognostic (5.13e-2)" "unprognostic (7.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-1)" 14.2 8.2 9.5 19.7 11.1 13.9 5.3 11.1 13.3 4.9 10.4 5.4 4.0 3.2 6.0 3.7 3.3 12.8 2.5 9.1 11.8 26.8 9.8 22.6 32.1 18.0 13.7 1.7 3.0 2.8 1.8 16.9 16.9 2.1 6.8 1.2 2.9 2.9 1.7 2.2 4.9 7.9 16.1 24.1 4.7 2.0 17.5 9.1 1.6 2.1 14.0 13.1 1.2 27.2 0.0 0.2 0.1 0.2 7.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 6.4 0.3 0.0 0.2 0.1 0.0 0.0 0.0 26.3 0.0 1.1 0.1 0.0 0.0 0.0 6.0 0.4 0.4 0.0 0.2 0.0 0.0 0.7 0.1 2.3 0.0 0.1 0.1 3.9 0.2 0.0 0.0 0.1 3.0 21.5 0.3 0.0 0.2 0.1 0.0 0.1 0.2 0.5 0.2 0.3 0.0 0.9 0.3 0.3 0.0 0.3 1.8 0.2 0.1 0.7 0.1 16.7 53.8 0.1 14.6 57.9 3.0 1.2 5.9 7.9 137.9 0.5 7.0 9.5 2.5 97.1 36.1 16.4 11.5 43.1 9.5 11.1 11.1 13.3 9.1 11.8 18.0 13.7 16.9 16.1 17.5 27.2 1.2 6.4 6.5 2.0 5.9 1.0 0.2 0.1 0.0 0.9 0.7 1.5 1.1 0.0 1.9 0.0 0.0 0.6 87.6 0.3 7.9 0.1 11.1 0.1 0.1 3.7 0.0 1.3 2.1 0.0 0.8 0.9 0.5 0.1 80.6 0.1 1.1 0.5 148.3 0.0 1.7 0.3 0.0 89.1 67.8 7.8 0.3 83.2 3.6 31.9 49.5 0.1 70.0 1.0 4.8 0.1 0.1 0.0 16.3 0.5 0.1 57.7 0.0 0.2 6.6 0.7 0.5 0.3 0.4 0.1 1.3 1.1 26.3 1.5 0.2 0.3 HCAR1 "FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR" ENSG00000196917 "Hydroxycarboxylic acid receptor 1" Q9BXC0 12 122726076-122730844 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 11.5;parathyroid gland: 40.4" "Group enriched" "Detected in some" 4 "Breast glandular cells: 8.7;Breast myoepithelial cells: 5.2;Club cells: 3.2;Early spermatids: 9.6;Extravillous trophoblasts: 3.7;Late spermatids: 6.5" "Cancer enhanced" "Detected in many" "breast cancer: 7.9" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 12.1;MCF7: 8.1;RT4: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "prognostic unfavorable (3.61e-5)" "unprognostic (8.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-2)" "unprognostic (3.80e-4)" "unprognostic (5.43e-4)" "unprognostic (1.41e-1)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.85e-3)" "unprognostic (1.26e-1)" "unprognostic (2.66e-3)" "unprognostic (2.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.38e-1)" "unprognostic (1.87e-2)" 5.5 0.3 0.4 0.2 0.4 1.0 11.5 1.7 0.7 0.7 0.4 0.1 0.3 0.4 1.2 0.2 1.7 0.2 0.2 0.6 0.1 0.8 0.1 0.4 0.4 0.3 0.1 0.4 0.1 40.4 0.3 1.0 0.3 1.0 0.1 0.6 5.0 5.1 1.2 0.7 0.3 0.2 0.1 2.3 2.0 0.8 0.2 0.3 1.3 0.1 0.1 1.2 0.3 1.2 0.1 0.3 0.2 0.3 0.0 0.0 1.9 0.1 0.0 0.0 0.1 2.5 12.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.6 1.8 0.2 0.3 0.2 0.6 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.6 0.1 8.1 0.2 0.4 0.3 3.0 0.6 0.3 0.2 0.3 0.1 35.3 2.6 0.2 0.1 4.2 0.0 0.3 3.4 0.1 0.3 0.4 0.2 0.2 0.2 0.4 0.1 0.4 0.2 0.2 0.3 2.0 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.1 0.1 0.4 0.4 1.7 0.7 0.6 0.1 0.3 0.1 0.3 0.1 0.2 1.2 1.3 0.0 0.5 0.0 0.0 0.1 1.4 0.2 0.0 0.3 8.7 5.2 0.4 0.0 3.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 9.6 0.2 0.2 0.3 0.0 0.0 0.0 0.0 3.7 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 6.5 0.3 0.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.0 0.1 1.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 1.0 HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;skin 1: 30.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 84.7;Basal respiratory cells: 52.0;Basal squamous epithelial cells: 120.1;Ionocytes: 87.5;Langerhans cells: 124.0;Suprabasal keratinocytes: 106.1" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 5.9" "Immune cell enriched" "Detected in many" 5 "neutrophil: 176.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 176.7" "Cell line enriched" "Detected in some" 6 "HaCaT: 118.4" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" 22.2 0.3 0.1 9.8 0.2 22.1 7.6 0.1 5.9 8.9 0.2 0.7 0.9 0.2 0.3 40.8 0.7 0.8 0.9 0.3 0.1 3.9 2.9 11.9 0.6 0.1 0.1 0.1 0.2 5.5 0.3 4.5 1.2 3.4 0.3 0.2 14.2 14.7 0.2 30.2 1.0 0.3 0.1 25.9 1.5 2.7 0.2 10.5 0.5 1.9 10.2 6.9 14.0 0.1 4.5 0.4 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 118.4 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.1 3.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 19.5 0.2 0.0 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 38.7 2.5 2.6 0.0 5.3 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 176.7 0.0 23.9 0.0 0.0 1.4 0.1 0.2 0.1 5.9 0.3 0.1 0.1 0.1 1.2 0.1 0.2 0.1 0.4 0.0 4.3 0.0 0.5 94.4 84.7 52.0 120.1 0.5 3.4 1.1 0.1 0.0 40.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 24.9 0.4 0.2 1.2 0.0 0.0 0.0 0.0 26.3 2.4 0.0 0.3 2.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 87.5 4.1 124.0 2.7 0.0 17.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 8.5 0.1 0.0 0.1 1.4 0.0 0.1 47.2 106.1 2.6 1.5 0.0 0.0 32.5 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Group enriched" "Detected in many" 4 "Astrocytes: 62.0;Early spermatids: 69.9;Excitatory neurons: 118.1;Inhibitory neurons: 84.9;Late spermatids: 59.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 85.5;Oligodendrocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Cell line enhanced" "Detected in many" "JURKAT: 49.1;MOLT-4: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 4.4 6.3 9.3 5.0 12.0 17.0 3.8 0.6 13.4 7.5 0.1 29.0 2.7 9.1 2.5 8.0 6.7 7.1 5.2 9.0 6.5 3.7 2.4 3.9 3.5 9.9 6.1 7.5 3.7 2.7 6.5 1.5 11.2 5.6 3.4 2.4 3.3 5.9 58.2 5.9 7.2 6.2 2.3 5.6 7.2 9.2 6.7 9.7 4.2 35.6 2.5 10.0 4.5 10.1 3.2 5.8 4.1 6.1 4.5 3.9 5.9 3.0 2.3 2.3 1.7 2.9 7.5 2.0 1.9 3.4 3.6 3.4 4.0 2.0 1.4 12.8 1.8 3.1 5.1 5.8 3.8 5.5 4.6 4.4 2.6 4.6 3.3 2.3 2.4 49.1 3.7 4.5 2.7 4.7 48.1 10.7 4.0 6.0 2.8 7.6 7.2 4.0 5.3 4.4 4.6 6.4 5.3 2.5 16.2 2.6 1.0 17.9 1.9 5.0 0.4 6.8 4.6 3.3 3.2 3.1 6.9 6.9 7.4 32.0 10.2 2.3 1.0 3.3 1.2 0.2 1.1 1.0 1.0 0.1 0.5 0.5 47.7 3.2 1.7 0.6 1.7 1.1 9.3 12.0 0.6 13.4 9.0 6.5 9.9 6.1 11.2 2.3 6.7 10.1 8.6 3.2 7.4 62.0 5.2 7.9 2.9 3.0 8.6 12.2 6.2 4.8 13.3 7.2 2.9 11.0 2.1 1.5 12.8 4.1 0.0 2.8 69.9 7.0 15.1 7.1 6.0 6.1 118.1 2.2 1.7 14.0 7.7 7.4 2.5 6.6 11.7 6.7 3.2 16.8 84.9 5.2 2.0 17.2 10.0 59.0 11.8 10.3 5.4 38.4 14.9 8.6 15.5 85.5 124.0 1.9 1.6 12.4 7.0 6.4 5.0 1.6 2.6 7.1 0.0 18.7 6.5 2.8 3.3 11.1 9.7 1.4 12.2 4.9 6.4 2.7 HDAC9 "HD7, HDAC, HDAC7B, KIAA0744, MITR" ENSG00000048052 "Histone deacetylase 9" Q9UKV0 7 18086949-19002416 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 47.5" "Group enriched" "Detected in many" 4 "Early spermatids: 244.6;Excitatory neurons: 376.2;Inhibitory neurons: 442.3;Microglial cells: 334.5;Oligodendrocyte precursor cells: 322.7;Oligodendrocytes: 233.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 74.1" "Group enriched" "Detected in all" 9 "B-cells: 52.6;dendritic cells: 74.1;monocytes: 24.4" "Cell line enhanced" "Detected in many" "HAP1: 163.6;hTERT-HME1: 79.4;SH-SY5Y: 65.7;U-698: 64.5;WM-115: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028926 Uncertain Approved Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA028926: AB_10602327" "unprognostic (2.06e-2)" "unprognostic (2.67e-1)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.74e-1)" "unprognostic (5.54e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-1)" "unprognostic (2.21e-1)" "unprognostic (2.45e-1)" "unprognostic (5.01e-1)" "unprognostic (7.58e-2)" "unprognostic (1.29e-1)" "unprognostic (3.94e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" 8.2 12.3 5.8 8.8 6.6 5.9 5.1 4.8 7.9 10.1 47.5 5.4 3.4 13.2 6.0 2.9 9.3 6.7 14.3 5.5 3.8 2.8 2.8 5.1 18.9 6.0 6.7 2.4 1.5 1.8 6.5 6.3 6.0 11.0 5.5 25.4 7.1 14.5 16.7 2.2 4.5 13.0 3.8 17.5 8.7 5.6 12.9 6.8 2.9 5.8 18.7 5.2 4.9 7.3 40.2 0.2 6.3 0.1 0.9 8.4 0.2 2.4 23.0 9.5 16.1 0.3 12.7 16.7 41.9 26.0 51.6 5.8 163.6 3.2 24.2 0.2 1.1 0.0 0.2 0.0 0.2 3.5 0.1 3.0 3.1 29.7 79.4 8.4 0.4 2.7 0.0 25.1 13.3 0.0 1.6 3.5 20.3 0.0 3.9 4.7 2.5 10.2 5.2 10.6 11.6 65.7 0.5 0.3 12.7 9.7 0.6 15.2 1.8 34.4 11.1 1.9 22.3 28.8 13.3 64.5 9.0 1.6 69.2 0.3 24.4 0.1 4.2 16.5 4.1 52.6 1.4 2.0 74.1 43.2 0.0 2.1 1.4 5.5 10.3 15.9 5.6 12.9 5.8 6.6 4.8 7.9 5.5 3.8 6.0 6.7 6.0 3.8 12.9 7.3 31.4 6.4 2.8 28.1 46.1 2.4 0.7 6.8 6.2 33.0 1.4 0.8 15.2 0.0 12.9 0.0 16.7 0.1 16.3 15.3 3.9 6.8 244.6 24.2 2.3 16.5 7.2 5.7 376.2 0.7 0.2 5.3 13.7 26.1 1.3 0.0 8.9 1.0 12.9 20.2 442.3 0.7 4.1 51.2 64.2 80.1 1.5 34.8 16.0 334.5 21.0 5.1 11.3 322.7 233.1 10.6 6.7 0.7 46.7 1.6 0.0 0.1 17.5 26.2 6.6 2.3 9.0 34.3 8.7 0.7 2.0 0.1 7.8 0.1 0.3 12.1 HDGF HMG1L2 ENSG00000143321 "Heparin binding growth factor" P51858 1 156742109-156766925 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "DNA-binding, Growth factor, Heparin-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026035, HPA048728, HPA053422" Enhanced Enhanced Nucleoplasm "Secreted to blood" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB026035: , HPA048728: AB_2680503, HPA053422: AB_2682146" "unprognostic (2.80e-1)" "unprognostic (9.63e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (9.06e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (2.43e-8)" "unprognostic (9.80e-3)" "unprognostic (2.34e-2)" "prognostic favorable (9.84e-4)" "unprognostic (2.45e-3)" "unprognostic (3.67e-2)" "unprognostic (1.40e-3)" "unprognostic (8.66e-3)" "unprognostic (2.14e-1)" "unprognostic (2.06e-1)" "unprognostic (3.86e-2)" 96.3 89.7 95.9 72.8 98.8 305.3 90.6 98.4 113.4 91.4 98.0 109.2 130.2 77.6 70.0 186.3 112.8 62.5 119.0 92.8 95.1 135.4 222.3 113.5 64.6 106.3 99.7 86.8 93.2 92.8 67.8 71.8 98.8 81.7 118.1 68.9 96.6 56.8 234.9 155.3 128.4 70.5 100.8 77.2 99.1 42.6 99.6 157.2 90.7 132.5 114.9 106.7 102.7 105.7 491.5 249.1 258.2 125.6 150.0 203.0 296.8 158.4 406.3 366.8 234.4 279.4 500.9 335.5 310.6 325.0 158.6 338.8 408.9 365.0 356.0 276.1 299.9 278.1 339.4 241.2 202.0 411.9 227.4 152.4 335.7 292.8 560.4 278.6 272.4 249.6 387.0 260.4 293.7 369.3 345.5 459.2 472.1 755.4 347.7 384.8 156.9 435.1 401.0 162.6 396.9 432.0 380.4 480.3 199.3 319.8 387.6 621.9 242.4 181.1 286.5 230.3 408.9 364.0 486.0 555.6 238.9 318.4 235.2 6.2 9.9 9.2 6.6 8.8 4.9 5.6 5.6 5.9 11.6 6.6 5.0 4.7 5.6 5.2 10.0 11.9 8.2 6.8 95.9 98.8 98.4 113.4 92.8 95.1 106.3 99.7 98.8 100.8 99.6 105.7 51.9 70.5 99.2 12.1 35.3 147.3 185.1 90.5 76.2 66.7 89.9 66.0 91.0 98.7 75.3 71.7 27.1 44.1 72.4 121.4 80.3 112.2 48.4 144.0 79.2 66.1 124.6 217.8 12.0 132.0 107.3 66.7 62.7 91.8 30.4 67.4 35.0 164.5 52.7 53.8 12.4 104.3 48.8 45.6 89.1 47.0 40.7 71.0 39.2 14.0 57.3 71.4 25.7 5.5 16.1 165.7 59.5 45.9 59.0 281.3 138.2 118.1 126.8 34.9 19.7 70.9 57.8 27.7 28.3 108.6 159.4 54.9 50.5 83.2 114.9 228.6 HEATR9 "C17orf66, FLJ32830" ENSG00000270379 "HEAT repeat containing 9" A2RTY3 17 35854946-35868891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 10.1" "Group enriched" "Detected in some" 17 "Early spermatids: 88.4;Late spermatids: 36.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA023129 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA023129: AB_1845599" "unprognostic (1.02e-1)" "unprognostic (2.63e-3)" "unprognostic (5.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (7.44e-4)" "unprognostic (1.30e-3)" "unprognostic (2.43e-2)" "unprognostic (2.63e-1)" "unprognostic (3.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.61e-10)" "unprognostic (6.78e-2)" "unprognostic (1.93e-1)" "unprognostic (4.52e-2)" "unprognostic (5.61e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 88.4 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.3 0.0 36.4 0.6 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 HEBP2 "C6orf34, SOUL" ENSG00000051620 "Heme binding protein 2" Q9Y5Z4 6 138403531-138422197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 678.8;Urothelial cells: 1174.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 219.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016928 Approved NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA016928: AB_1850572" "unprognostic (8.53e-2)" "unprognostic (1.54e-1)" "unprognostic (7.92e-2)" "unprognostic (6.88e-2)" "unprognostic (7.96e-2)" "unprognostic (1.48e-1)" "unprognostic (5.60e-2)" "unprognostic (1.62e-2)" "unprognostic (1.50e-1)" "unprognostic (2.48e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.47e-5)" "unprognostic (2.76e-3)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "prognostic favorable (3.07e-4)" 168.1 34.4 13.9 15.0 11.2 31.8 147.3 13.8 13.8 50.6 14.8 51.7 21.9 35.2 28.0 131.1 30.4 12.8 78.5 11.2 15.8 42.4 72.3 26.4 7.0 14.1 17.4 27.8 37.2 14.6 27.2 13.3 14.8 52.7 19.2 10.1 72.2 10.5 132.8 80.4 32.7 13.3 13.4 17.6 54.3 7.5 22.9 8.6 27.0 33.5 12.3 51.5 81.5 12.5 42.8 8.6 13.6 45.4 42.5 17.1 88.2 45.7 12.8 6.0 9.9 23.2 28.3 1.3 74.0 24.0 29.0 40.0 13.2 22.7 3.4 31.0 60.8 17.4 8.7 42.9 24.8 27.4 0.1 20.8 25.8 6.5 22.6 32.2 23.7 31.5 40.7 23.4 10.5 34.9 9.0 83.7 17.7 22.2 33.1 29.1 20.5 26.1 26.5 31.8 31.0 5.7 47.5 85.5 29.4 21.0 27.6 219.5 28.9 14.5 40.8 18.7 46.1 36.5 31.5 17.2 25.2 41.6 9.4 5.6 7.9 5.6 1.5 8.2 2.0 5.0 4.3 2.5 7.4 2.9 2.0 1.7 14.6 1.9 5.0 4.6 6.4 2.3 13.9 11.2 13.8 13.8 11.2 15.8 14.1 17.4 14.8 13.4 22.9 12.5 106.3 19.2 31.6 5.9 48.7 117.5 387.1 73.4 71.7 28.6 274.7 262.4 160.8 190.1 98.1 121.4 14.6 273.3 49.2 231.9 295.4 304.3 4.5 167.0 104.2 91.7 102.2 38.3 1.1 578.1 408.5 70.7 72.9 229.9 45.1 38.4 74.6 547.6 93.6 18.5 1.0 169.4 79.3 84.7 58.5 10.9 67.7 70.9 58.7 8.4 98.3 90.5 51.5 3.5 1.8 678.8 224.6 66.5 68.2 510.0 115.2 353.0 72.7 38.9 59.2 78.4 89.0 11.7 58.2 201.2 204.9 291.3 59.9 29.2 141.8 1174.8 HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112629-43566001 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 16.4;kidney: 7.8" "Cell type enhanced" "Detected in some" "Early spermatids: 135.6;Excitatory neurons: 533.3;Inhibitory neurons: 157.3;Late spermatids: 72.0;Oligodendrocyte precursor cells: 277.9" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "cerebral cortex: 16.4" "Group enriched" "Detected in some" 4 "basophil: 4.9;neutrophil: 3.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.9" "Cell line enhanced" "Detected in some" "A549: 3.8;GAMG: 3.7;U-266/70: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Uncertain Supported Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA007203: AB_2667776, HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" 0.1 0.0 1.5 0.2 1.7 0.5 0.2 0.0 16.4 0.1 0.0 0.2 0.0 0.2 0.6 1.0 0.1 1.9 0.0 0.7 0.0 7.8 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.3 0.1 2.2 0.4 0.2 0.9 0.6 0.1 0.1 0.0 0.1 0.3 1.8 0.2 0.0 0.5 2.6 0.2 0.3 0.1 3.8 0.0 3.8 0.3 0.5 0.0 0.0 0.0 1.2 2.2 0.1 0.5 0.0 0.0 0.2 2.3 2.2 3.7 0.2 0.0 0.0 0.2 0.1 0.7 0.0 0.3 0.2 0.2 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 1.8 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.6 0.8 0.9 0.3 12.0 0.4 0.0 2.7 0.3 0.0 4.9 0.8 0.7 0.3 0.5 0.2 0.6 0.3 0.1 0.1 1.0 0.3 0.3 3.3 0.6 0.6 0.9 0.1 0.0 1.5 1.7 0.0 16.4 0.7 0.0 0.2 0.0 0.1 0.0 0.2 3.8 0.0 0.0 0.0 7.8 0.1 0.4 0.3 0.0 0.0 15.4 0.1 0.3 1.4 0.0 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 135.6 1.1 3.6 0.2 0.0 0.0 533.3 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.4 0.1 0.0 45.4 157.3 0.1 0.0 0.0 1.4 72.0 0.3 0.2 0.0 24.4 0.1 0.6 0.0 277.9 4.8 0.0 1.4 0.4 0.0 0.4 4.3 15.8 0.0 1.9 0.0 0.6 0.4 3.2 3.3 0.3 0.3 0.0 0.6 0.2 0.5 0.3 HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 90.1;Cardiomyocytes: 90.5;Cone photoreceptor cells: 264.8;Endothelial cells: 121.5;Hepatic stellate cells: 130.3;Microglial cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 174.1;HHSteC: 241.5;hTERT-RPE1: 351.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 510000000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" 30.1 9.9 19.3 19.2 23.2 1.9 14.8 27.0 15.0 20.8 28.3 11.9 8.0 19.2 6.2 16.1 13.2 38.9 67.3 14.3 22.7 15.2 7.5 55.1 16.5 32.0 28.1 12.4 31.6 16.1 3.6 33.4 28.6 13.9 12.2 46.8 7.7 14.6 14.3 5.2 9.4 25.4 27.3 17.9 9.8 13.5 30.3 8.6 52.2 24.2 15.7 30.0 10.1 30.6 7.0 7.1 54.7 4.2 73.2 58.7 21.1 64.9 90.1 72.6 83.5 58.5 1.0 2.8 43.8 174.1 52.3 15.3 7.4 31.6 97.9 6.5 3.7 1.3 42.3 8.4 241.5 1.8 80.6 77.8 10.1 87.4 21.5 351.3 69.3 5.0 0.1 1.0 25.7 1.3 2.8 0.1 10.1 0.1 5.5 4.8 41.0 0.2 14.6 1.2 1.0 5.6 134.8 10.6 6.4 55.1 24.2 4.3 93.9 37.7 41.3 150.5 29.1 6.9 19.7 0.4 76.8 6.5 82.4 1.1 0.1 0.0 1.9 1.7 1.1 0.5 0.6 1.7 0.4 0.3 1.2 0.8 0.0 3.9 1.9 0.4 0.2 0.5 19.3 23.2 27.0 15.0 14.3 22.7 32.0 28.1 28.6 27.3 30.3 30.6 90.1 86.6 5.8 28.7 4.9 5.0 8.0 25.4 6.8 6.1 2.4 5.7 90.5 7.2 6.5 27.6 264.8 1.8 19.2 0.5 0.0 32.0 7.0 4.0 20.1 121.5 0.0 6.1 0.9 6.4 65.3 44.8 1.1 2.2 26.6 24.9 130.3 3.5 6.8 1.7 14.9 0.5 4.1 18.4 7.3 9.4 5.0 7.1 7.2 92.8 4.0 6.0 35.0 13.0 57.6 6.4 0.1 13.9 8.6 5.2 0.8 1.3 1.0 66.8 0.0 24.0 28.7 1.0 1.1 2.7 4.4 3.3 14.2 3.1 0.1 1.3 HEPACAM "FLJ25530, GLIALCAM" ENSG00000165478 "Hepatic and glial cell adhesion molecule" Q14CZ8 11 124919205-124936412 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell cycle, Growth arrest, Growth regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 222.6;choroid plexus: 79.7" "Group enriched" "Detected in some" 9 "Astrocytes: 184.8;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 163.2" "Cancer enriched" "Detected in some" 12 "glioma: 29.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "Hep G2: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017613, CAB025486" Enhanced Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB025486: , HPA017613: AB_1850595" "unprognostic (3.22e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-1)" "unprognostic (6.41e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.33e-2)" "unprognostic (1.06e-6)" "unprognostic (2.62e-1)" "unprognostic (3.21e-1)" 15.6 0.3 172.8 0.2 203.3 0.0 2.5 170.4 162.1 0.2 79.7 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.2 163.2 156.1 0.1 16.2 0.0 0.2 222.6 182.8 0.0 0.0 0.0 0.8 0.0 183.6 0.2 0.2 1.8 0.2 0.5 0.1 0.0 0.2 0.1 205.7 0.0 0.1 0.2 182.0 0.0 0.0 0.3 0.6 0.0 0.1 212.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.2 172.8 203.3 170.4 162.1 163.2 156.1 222.6 182.8 183.6 205.7 182.0 212.2 0.1 0.0 0.0 184.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.6 0.0 15.5 0.0 72.9 163.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "intestine: 96.2" "Group enriched" "Detected in some" 11 "Enteroendocrine cells: 218.2;Intestinal goblet cells: 387.5;Ionocytes: 349.9;Paneth cells: 318.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.4;pancreatic cancer: 10.7;renal cancer: 10.6;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 36 "SCLC-21H: 172.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 210000 "Cluster 9: Intestine - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: AB_1853037" "unprognostic (2.01e-3)" "unprognostic (6.05e-2)" "prognostic favorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (7.27e-2)" "unprognostic (2.24e-2)" "unprognostic (4.48e-2)" "unprognostic (8.40e-3)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (5.37e-3)" "unprognostic (4.93e-2)" "unprognostic (3.64e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (3.82e-1)" "unprognostic (6.34e-2)" 0.1 0.1 0.0 2.3 0.0 2.5 8.9 0.0 0.1 0.0 0.0 64.3 30.1 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 15.2 0.0 0.1 0.0 0.1 0.1 0.0 4.3 0.4 7.3 0.2 0.0 0.8 96.2 0.0 2.6 1.4 0.0 0.0 48.0 1.5 0.1 0.1 10.1 3.2 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 172.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.4 0.3 1.1 0.7 0.0 0.0 15.1 6.6 0.2 0.0 0.9 5.5 0.0 0.0 0.0 17.2 9.8 0.1 2.5 0.0 0.0 0.1 218.2 18.7 0.5 0.0 0.0 0.1 27.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 387.5 349.9 0.0 0.0 2.4 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 2.2 0.0 318.1 0.0 0.1 0.9 11.5 0.0 0.3 0.0 0.0 0.0 0.1 5.6 1.2 0.0 0.1 0.1 0.1 0.0 19.7 0.3 HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.5;Hofbauer cells: 340.2;Syncytiotrophoblasts: 493.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 746.0;GAMG: 646.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" NA NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" 92.2 72.0 22.1 59.7 25.3 59.9 83.0 22.3 32.5 97.6 39.4 105.0 99.0 71.5 321.4 38.5 66.7 99.0 84.3 23.1 26.2 81.6 137.5 111.3 47.0 23.8 22.9 62.4 103.6 94.2 46.6 319.4 24.7 98.7 116.9 33.6 123.4 54.0 43.3 54.3 75.4 76.1 23.2 64.7 88.4 19.6 28.2 29.1 89.6 38.4 40.4 94.6 64.1 30.4 147.3 111.0 39.4 131.8 746.0 232.3 122.3 173.5 590.4 175.0 375.2 130.6 194.5 0.0 133.0 152.2 646.3 115.2 43.2 185.2 228.7 79.2 72.6 19.1 101.4 101.5 216.5 16.2 152.3 206.7 108.0 180.7 121.3 275.9 204.5 47.3 54.3 236.9 194.9 145.7 19.8 36.6 36.8 142.7 47.8 43.9 56.2 191.8 119.8 130.4 24.5 30.4 134.2 92.6 180.0 68.8 99.1 108.6 118.5 112.1 26.6 207.8 165.6 102.6 191.3 0.9 257.9 143.6 209.8 86.2 343.2 99.1 69.3 129.9 80.7 45.2 56.1 64.0 310.8 28.1 52.6 51.3 125.2 42.4 82.5 93.4 73.2 269.0 22.1 25.3 22.3 32.5 23.1 26.2 23.8 22.9 24.7 23.2 28.2 30.4 49.6 41.7 38.4 5.9 31.5 44.0 82.8 103.2 21.6 10.2 26.3 27.6 19.8 82.9 63.8 29.5 8.4 466.5 32.8 68.2 19.6 151.3 1.3 21.0 21.4 56.2 22.8 23.1 32.2 125.6 175.4 107.2 33.6 26.9 69.8 19.8 74.3 70.1 340.2 10.1 24.3 56.7 107.8 127.3 134.3 3.4 85.1 168.8 72.9 17.8 114.2 35.4 29.9 22.6 13.3 65.8 54.8 72.2 71.5 74.2 99.5 79.6 36.3 16.3 46.0 32.6 49.5 0.3 1.4 23.8 32.5 493.6 35.3 31.4 81.8 71.0 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 HEYL "bHLHb33, HESR3, HEY3" ENSG00000163909 "Hes related family bHLH transcription factor with YRPW motif like" Q9NQ87 1 39623435-39639643 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 69.5" "Cell type enhanced" "Detected in many" "Late spermatids: 17.5;Leydig cells: 26.1;Peritubular cells: 56.8;Sertoli cells: 52.6;Skeletal myocytes: 33.4;Smooth muscle cells: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 8.0;LHCN-M2: 20.8;RH-30: 26.5;THP-1: 6.2;U-266/84: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001438, HPA076960" Approved Approved Mitochondria,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA001438: AB_1079052, HPA076960: AB_2732326" "unprognostic (1.98e-2)" "unprognostic (7.92e-2)" "unprognostic (4.19e-3)" "unprognostic (3.49e-1)" "unprognostic (2.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (7.20e-2)" "unprognostic (5.92e-2)" "unprognostic (1.19e-2)" "unprognostic (2.35e-1)" "unprognostic (8.50e-2)" "prognostic unfavorable (2.26e-6)" "prognostic unfavorable (3.57e-4)" "unprognostic (2.67e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.63e-5)" 17.9 12.4 9.5 5.6 12.0 0.1 9.3 10.5 6.9 18.5 4.1 7.2 1.9 27.9 5.7 4.8 17.4 8.0 57.0 5.4 15.0 9.5 4.2 23.5 1.7 11.3 15.6 13.4 69.5 2.4 15.3 29.5 12.9 17.0 3.4 6.7 2.7 14.4 6.0 2.9 4.9 25.0 7.3 6.3 6.0 16.0 17.1 1.3 20.4 5.4 2.0 8.7 11.3 8.3 0.0 2.8 4.8 0.0 0.0 0.5 0.3 0.0 0.1 0.0 0.1 2.0 0.3 0.0 1.6 0.5 0.0 0.0 2.8 0.0 0.3 0.0 3.2 5.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 8.0 0.5 0.7 20.8 1.9 0.0 0.1 0.0 0.2 0.1 1.4 26.5 0.2 0.0 0.5 0.6 0.0 0.0 0.1 0.0 1.1 0.0 6.2 0.0 0.0 0.2 0.0 0.0 0.7 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 12.0 10.5 6.9 5.4 15.0 11.3 15.6 12.9 7.3 17.1 8.3 1.3 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.9 0.1 0.0 3.6 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 1.0 5.4 1.3 4.0 1.9 0.0 0.0 0.1 3.5 0.3 13.3 2.0 2.4 0.0 0.7 1.4 0.0 0.3 1.7 0.2 0.2 0.0 0.0 2.3 17.5 26.1 0.4 5.4 4.7 0.1 0.4 0.0 0.0 2.4 2.8 0.3 56.8 0.0 0.2 0.0 0.1 0.0 3.9 52.6 33.4 29.5 0.4 2.0 0.1 0.1 0.3 0.3 1.9 0.4 0.2 HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 200.3;liver: 752.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 103.7;Endometrial ciliated cells: 113.9;Glandular and luminal cells: 127.8;Hepatocytes: 534.7;Proximal tubular cells: 477.5" "Cancer enriched" "Detected in many" 4 "liver cancer: 119.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "CACO-2: 55.8;EFO-21: 82.7;Hep G2: 186.6;OE19: 328.0;RPTEC TERT1: 212.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.2" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" 0.4 0.3 0.4 2.5 1.9 0.5 12.5 0.6 0.8 27.4 1.5 16.7 31.6 3.1 13.0 0.4 4.2 61.7 0.3 0.5 0.4 200.3 752.6 0.8 0.4 0.4 0.4 0.2 31.2 7.0 0.2 0.2 0.4 44.5 20.3 0.7 4.2 4.2 0.1 0.9 25.6 0.5 0.4 0.6 25.5 0.1 0.5 0.7 55.1 0.2 0.1 0.2 0.1 0.6 0.0 12.3 4.6 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 55.8 10.7 0.1 82.7 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.2 186.6 0.0 0.4 1.0 0.0 0.2 0.1 0.0 0.1 0.1 0.4 0.0 0.3 0.5 0.0 0.0 0.2 0.3 328.0 0.0 0.1 0.3 0.1 212.2 0.0 0.2 0.2 0.2 0.9 0.0 0.0 0.2 1.0 0.6 0.1 0.9 0.2 0.1 0.0 0.3 0.5 0.2 0.8 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.4 1.9 0.6 0.8 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.6 0.1 0.0 2.0 0.3 5.9 0.0 0.4 0.6 0.0 0.3 7.5 1.7 0.3 81.5 4.9 27.6 2.1 0.0 0.3 18.5 103.7 7.2 0.2 113.9 17.1 1.2 43.8 24.0 3.2 17.8 0.0 0.4 19.4 127.8 1.3 0.0 16.4 534.7 0.2 0.0 0.6 16.0 2.0 16.1 0.0 0.0 0.0 21.3 0.0 1.9 2.0 4.2 0.0 0.0 0.5 12.1 35.6 0.0 0.0 12.9 54.6 477.5 4.1 0.2 0.0 0.2 1.1 0.1 0.0 0.0 0.0 0.0 3.8 0.4 9.1 0.4 HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 111.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 71.4;Intestinal goblet cells: 89.5;Paneth cells: 87.8;Proximal enterocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 115.9;OE19: 99.2;SH-SY5Y: 56.7;SK-BR-3: 172.6;T-47d: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "HPA031406: AB_2673866" "unprognostic (7.41e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (4.47e-3)" "unprognostic (6.79e-3)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-1)" "unprognostic (3.90e-1)" "unprognostic (1.54e-3)" "unprognostic (1.37e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.34e-4)" 13.2 5.8 21.7 6.6 26.9 2.0 23.2 41.5 33.3 19.9 2.8 17.9 39.1 11.9 29.1 5.5 19.0 21.6 12.4 22.0 24.3 12.3 4.4 20.4 5.3 27.4 22.7 3.0 111.2 14.4 44.0 20.1 30.3 36.2 17.9 8.7 86.2 20.2 4.6 7.6 27.3 6.3 10.4 16.7 68.7 6.8 25.4 2.8 16.8 5.7 6.3 12.3 7.6 39.1 5.2 11.4 1.3 15.8 0.0 0.0 2.7 0.0 0.6 1.1 1.0 10.6 5.8 0.0 1.0 0.0 1.4 4.9 14.5 1.0 0.8 0.0 11.4 0.1 0.3 10.1 2.7 0.0 1.1 0.2 6.0 0.1 2.4 0.3 26.0 3.8 0.7 4.0 0.0 115.9 0.7 0.2 0.4 99.2 7.1 0.2 0.0 21.8 14.5 44.8 21.1 56.7 0.0 172.6 0.0 3.6 101.2 0.0 0.5 0.1 1.4 0.4 0.0 2.0 0.3 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.9 0.7 0.0 0.1 1.0 1.1 0.0 0.0 0.0 2.6 0.0 0.4 21.7 26.9 41.5 33.3 22.0 24.3 27.4 22.7 30.3 10.4 25.4 39.1 21.4 0.0 5.5 4.9 4.6 1.5 2.6 3.1 0.6 14.3 20.4 12.3 3.8 4.3 8.6 0.0 0.0 26.3 1.1 16.0 3.9 19.0 0.4 10.2 3.0 19.1 35.3 0.0 16.1 26.9 1.7 1.0 71.4 20.3 0.0 1.1 20.7 0.4 2.5 20.2 15.5 89.5 16.2 0.8 0.4 1.0 0.9 0.7 7.2 6.5 0.6 2.8 0.0 8.0 50.9 22.9 87.8 0.0 22.7 17.8 107.4 0.5 6.5 4.4 0.0 1.5 1.8 0.4 2.1 0.5 0.4 35.0 1.8 0.1 15.6 13.9 HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 32: Non-specific - Translation" Mitochondria Cytosol "HPA042715: AB_2678127" "unprognostic (9.24e-2)" "unprognostic (6.31e-3)" "unprognostic (7.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (1.98e-2)" "unprognostic (3.11e-3)" "unprognostic (9.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.09e-2)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" 146.1 175.6 143.3 87.0 146.2 133.1 113.5 147.2 175.0 104.7 168.0 199.4 118.9 111.7 51.3 130.0 105.0 80.5 318.7 139.8 146.0 182.7 163.3 95.7 132.9 143.9 142.2 118.7 108.7 204.9 125.1 54.6 141.6 127.9 96.3 45.5 163.2 92.7 422.5 140.8 136.6 68.1 145.3 129.3 148.6 66.0 149.0 110.7 114.0 297.9 92.7 152.3 105.2 145.7 104.9 166.6 99.0 172.6 98.5 186.4 262.2 66.6 109.7 164.7 206.4 176.0 202.2 183.3 149.9 107.1 214.2 127.3 146.2 260.6 65.9 424.0 234.0 92.6 161.7 244.7 137.4 149.7 230.1 238.2 213.2 93.7 113.3 126.3 141.7 146.5 104.0 341.5 124.0 315.9 165.3 178.1 124.8 195.5 181.7 157.1 75.6 324.7 265.5 158.7 107.9 141.5 71.4 295.2 310.5 100.7 173.3 233.7 96.8 118.5 124.7 110.2 142.5 165.2 216.6 158.4 150.5 254.1 77.5 284.2 743.6 219.8 391.2 975.8 389.5 618.1 540.1 452.6 930.0 496.0 488.1 464.2 124.6 308.0 1024.9 616.8 621.8 971.3 143.3 146.2 147.2 175.0 139.8 146.0 143.9 142.2 141.6 145.3 149.0 145.7 100.4 73.7 78.6 0.0 212.5 232.2 332.8 358.0 272.0 60.5 225.5 288.5 145.3 174.5 191.0 182.1 12.5 223.0 184.2 415.6 534.1 204.5 83.9 140.0 120.6 110.9 266.6 90.8 0.0 237.3 185.4 129.1 142.2 124.2 130.0 157.0 120.3 217.0 378.7 65.6 0.0 450.7 219.7 458.8 345.2 56.8 140.1 292.1 257.9 0.0 449.7 138.1 230.7 0.0 0.0 110.0 493.0 85.0 184.2 292.6 313.8 542.8 142.3 47.7 118.3 145.9 138.8 96.7 79.4 301.8 225.0 280.2 223.7 182.1 385.3 532.4 HINT1 "HINT, PKCI-1, PRKCNH1" ENSG00000169567 "Histidine triad nucleotide binding protein 1" P49773 5 131155383-131224468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 3537.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044577 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Plasma membrane" "HPA044577: AB_10795618" "unprognostic (2.00e-1)" "unprognostic (9.27e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (8.30e-3)" "unprognostic (2.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.49e-2)" "unprognostic (6.50e-3)" "unprognostic (4.43e-2)" "unprognostic (4.39e-3)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (3.68e-1)" 132.6 175.0 235.7 139.8 245.1 259.3 172.7 241.6 326.2 117.6 243.8 227.6 176.1 119.6 187.5 181.3 165.6 108.0 167.2 245.9 247.8 256.7 474.2 119.0 206.5 241.6 237.2 121.5 165.5 285.6 152.5 87.5 249.1 155.1 226.5 110.8 172.8 116.4 334.1 170.0 196.3 124.2 242.6 126.9 136.5 80.1 240.8 166.5 177.2 278.4 192.3 152.9 129.7 245.3 437.1 522.7 448.2 877.2 273.1 297.1 441.3 300.3 230.9 235.4 272.1 547.1 516.8 563.3 625.7 329.6 569.1 253.4 315.4 635.3 244.1 500.0 514.6 199.1 814.0 771.9 532.6 349.4 65.4 400.1 618.6 295.8 528.2 533.7 314.1 727.8 313.4 1132.1 338.8 419.9 548.0 945.6 415.6 425.6 362.0 407.9 436.1 988.1 500.6 567.0 563.3 351.9 380.5 243.5 612.0 574.4 291.2 520.8 396.0 351.7 244.0 323.0 684.2 342.3 561.4 578.8 497.8 586.8 346.3 179.8 187.9 85.0 196.3 109.9 298.0 384.9 462.0 294.2 396.9 332.6 416.0 325.5 35.6 269.0 128.0 521.4 362.5 608.6 235.7 245.1 241.6 326.2 245.9 247.8 241.6 237.2 249.1 242.6 240.8 245.3 582.7 282.0 279.1 34.3 718.2 1301.2 1472.2 1928.1 889.5 191.2 1134.3 1831.1 517.0 1028.0 882.2 715.4 45.9 780.9 641.6 1245.1 1663.0 1024.5 783.0 718.9 443.7 501.2 698.1 669.7 53.8 774.3 1632.8 400.2 355.2 753.7 108.2 666.5 436.2 2380.1 887.1 148.0 48.0 947.2 915.5 472.4 906.9 206.3 392.4 447.0 965.8 34.7 1269.4 405.1 488.1 26.7 55.4 894.3 1094.2 418.6 679.7 1998.9 1690.3 3537.5 708.3 194.0 243.3 287.0 730.3 625.5 197.9 1109.1 1146.1 456.8 671.1 464.3 1280.4 1713.2 HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 633.9;Hepatocytes: 457.4;Proximal tubular cells: 578.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" 50.8 79.5 41.7 15.5 43.9 27.0 48.5 44.9 46.8 23.2 40.3 42.6 34.9 25.9 48.6 27.5 29.9 14.9 87.4 39.8 43.1 91.1 169.2 30.2 21.0 43.8 42.5 19.2 65.9 72.6 41.2 17.6 42.0 33.9 34.2 20.4 39.7 26.1 80.1 33.4 34.2 20.1 43.9 33.8 56.9 29.8 47.3 38.8 38.4 85.5 23.8 30.6 24.2 44.0 30.3 76.1 47.1 45.6 29.0 24.3 33.2 27.8 39.2 42.3 46.1 49.9 31.1 39.9 31.7 25.3 59.8 29.3 21.2 40.9 44.1 87.8 40.7 42.2 64.1 45.8 68.1 25.1 40.0 27.3 36.8 40.2 64.8 16.7 33.2 91.4 25.5 117.4 34.0 60.3 61.3 31.3 21.4 70.0 138.7 60.8 33.1 53.6 61.5 21.5 38.4 46.4 36.0 42.7 49.6 27.5 45.9 44.6 16.5 22.0 37.7 30.4 35.7 107.0 127.3 57.4 49.8 32.2 36.2 41.0 77.5 4.7 68.9 58.5 62.4 98.9 73.7 69.8 113.4 96.7 56.4 58.6 7.6 66.8 56.9 246.1 107.3 81.2 41.7 43.9 44.9 46.8 39.8 43.1 43.8 42.5 42.0 43.9 47.3 44.0 49.3 22.4 17.5 5.2 57.9 45.4 63.4 137.6 49.5 39.8 99.1 105.8 115.1 130.1 68.3 80.9 20.9 154.9 69.3 148.2 633.9 115.5 67.3 83.9 28.6 47.8 96.0 100.8 1.7 172.1 71.7 53.2 52.5 44.6 18.4 43.5 63.1 457.4 113.9 20.2 2.5 127.4 126.1 61.1 51.4 128.0 40.4 47.7 120.9 1.9 74.1 123.7 87.6 1.5 4.5 85.6 157.5 44.8 77.7 40.7 181.4 578.1 105.1 45.5 46.0 54.2 72.6 38.4 77.4 64.7 45.9 56.8 51.0 85.1 126.7 84.8 HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777998 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "brain: 397.5" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 463.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 27.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.5" "Cell line enhanced" "Detected in many" "HDLM-2: 120.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA007611: AB_1850730" "unprognostic (1.35e-3)" "unprognostic (1.49e-2)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (5.50e-2)" "unprognostic (9.44e-2)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.42e-3)" "unprognostic (4.58e-2)" "prognostic favorable (9.99e-4)" "unprognostic (1.38e-1)" "unprognostic (7.82e-2)" "unprognostic (3.93e-3)" "unprognostic (1.03e-2)" 19.8 9.2 253.4 6.9 359.7 15.0 10.3 124.8 187.0 4.3 39.4 6.6 7.4 6.0 4.1 9.2 8.8 4.7 30.3 146.3 235.5 25.5 14.9 10.7 4.1 253.8 268.7 5.5 11.5 11.5 8.9 10.1 192.5 9.3 4.8 27.8 12.1 5.7 23.5 3.0 6.3 3.9 187.4 6.9 14.5 1.9 318.3 6.9 9.3 17.0 4.2 6.0 5.2 397.5 11.7 51.4 23.2 14.3 55.2 39.4 2.7 6.4 6.3 7.0 7.3 3.8 6.3 0.0 14.3 12.1 43.2 0.6 10.7 16.6 17.5 120.9 4.3 53.7 8.7 18.4 31.0 14.9 14.0 60.3 10.5 32.4 47.9 16.5 17.6 10.0 31.7 14.4 54.3 8.9 18.9 10.6 5.9 6.6 34.3 22.1 12.7 1.6 31.5 2.0 14.1 12.9 14.4 0.5 7.0 4.3 7.9 6.0 59.5 24.5 11.6 28.5 31.4 68.7 44.3 10.2 49.4 7.7 13.4 27.5 1.3 3.5 0.2 1.1 0.3 0.6 0.5 0.2 0.6 0.5 1.6 0.5 1.7 0.2 4.1 0.2 0.1 0.7 253.4 359.7 124.8 187.0 146.3 235.5 253.8 268.7 192.5 187.4 318.3 397.5 107.8 16.0 31.2 82.6 45.8 9.3 30.6 24.9 16.5 116.0 65.6 32.6 213.9 55.8 35.6 64.4 152.2 8.8 72.0 38.4 35.2 32.5 3.1 39.1 12.2 80.3 67.2 18.5 17.8 67.0 1.5 28.1 70.8 41.7 44.9 24.3 151.0 145.2 15.7 222.1 36.3 32.2 63.1 119.5 10.9 4.0 13.1 53.2 44.4 49.6 47.6 78.0 95.8 145.3 463.7 63.4 24.6 18.8 97.9 118.9 22.5 75.0 48.7 62.9 46.0 96.6 60.8 2.7 4.8 42.5 9.5 9.6 30.5 20.1 29.3 43.9 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74834127-74893359 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 144.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 216.4;Early spermatids: 89.5;Paneth cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 172.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028587, HPA061711" Enhanced Supported Vesicles,Centrosome,Mitochondria,Cytosol NA NA 100000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Mitochondria, Cytosol" "Vesicles, Centrosome" "HPA028587: AB_10602605, HPA061711: " "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 58.2 2.7 2.7 14.6 3.9 45.7 16.0 4.8 5.6 7.8 2.7 46.6 2.8 5.1 66.1 19.9 9.7 9.5 7.9 3.5 3.6 1.9 2.7 15.2 5.8 11.1 6.3 14.9 2.9 2.5 1.9 13.1 8.5 4.9 37.3 144.0 14.7 1.1 45.6 14.6 13.0 3.3 5.9 6.9 18.7 32.8 6.0 3.7 14.1 83.7 7.8 27.1 15.9 8.6 55.9 0.4 12.5 45.4 103.3 10.8 46.5 21.3 30.6 23.4 33.4 44.0 9.8 40.7 20.1 9.9 30.2 19.0 57.0 44.7 67.0 11.6 12.5 55.1 12.4 61.0 32.5 80.8 86.3 18.2 47.3 44.5 77.1 26.3 11.3 23.0 49.2 0.2 6.9 39.6 19.8 82.0 45.3 52.4 38.2 31.8 26.2 31.7 14.2 77.2 9.2 44.6 13.5 67.4 27.4 17.8 3.6 12.8 9.4 74.0 13.4 31.2 39.2 27.1 8.2 20.2 172.5 57.9 19.9 16.8 14.0 51.7 0.2 11.0 0.6 1.2 0.8 0.1 11.8 1.3 1.2 1.2 11.2 0.0 7.7 0.3 1.5 4.7 2.7 3.9 4.8 5.6 3.5 3.6 11.1 6.3 8.5 5.9 6.0 8.6 1.6 16.0 45.3 4.9 5.7 51.6 9.5 26.7 5.7 14.8 16.0 5.6 7.2 4.3 24.2 5.5 83.4 2.3 0.6 216.4 0.0 4.6 89.5 5.8 4.1 4.4 39.0 4.2 0.2 4.5 33.5 6.4 14.8 15.0 22.2 27.2 1.4 0.3 15.8 21.9 0.1 37.7 6.1 20.8 35.1 46.0 14.6 22.8 23.2 25.3 18.9 6.3 2.1 0.5 0.7 25.6 108.3 7.9 4.7 34.3 5.4 0.2 15.2 42.1 13.1 19.9 3.3 3.9 4.2 10.7 57.0 8.2 3.6 5.8 51.7 70.0 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 13 "Early spermatids: 11.1;Hofbauer cells: 34.5;Kupffer cells: 43.9;Macrophages: 38.8;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cell line enriched" "Detected in some" 5 "U-937: 20.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 8.4 4.5 0.0 19.0 0.2 129.3 2.6 1.4 1.6 0.8 0.2 2.5 2.0 1.0 0.1 0.9 5.1 2.1 4.0 0.2 0.0 1.8 5.2 25.1 4.2 0.0 0.0 1.0 1.5 0.1 0.7 2.8 0.0 1.1 1.4 0.1 1.5 0.3 0.9 0.5 3.1 7.9 0.0 76.6 2.1 1.3 2.4 1.4 1.3 0.5 0.7 4.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.1 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.6 0.0 569.7 92.5 204.8 0.3 179.4 0.2 0.4 0.2 0.1 30.2 0.2 0.1 0.1 32.2 0.2 200.9 1.4 0.2 43.6 0.0 0.2 1.4 1.6 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.4 1.3 0.0 0.4 0.2 34.5 0.0 0.4 0.0 0.0 43.9 0.9 1.8 0.0 38.8 0.0 1.0 14.6 0.0 2.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.0 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.5" "Cell type enhanced" "Detected in many" "Adipocytes: 35.7;Endothelial cells: 32.5;Hepatic stellate cells: 47.5;Hofbauer cells: 34.1;Kupffer cells: 24.8;Langerhans cells: 23.5;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 65.1;neutrophil: 55.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 65.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 32.4;THP-1: 100.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA005968: AB_1079066" "unprognostic (6.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.57e-2)" "unprognostic (9.19e-3)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (5.14e-3)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.28e-6)" "unprognostic (8.44e-3)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" 35.2 4.7 1.4 10.3 1.3 86.5 18.6 1.4 2.0 7.5 1.5 44.4 4.8 5.5 0.5 3.9 9.3 9.6 18.9 2.0 1.6 6.8 21.8 23.1 8.5 1.9 1.7 4.2 4.3 1.3 3.0 13.8 2.0 6.3 2.0 0.0 3.5 0.4 9.2 8.7 18.9 5.6 1.9 15.7 5.2 1.8 2.6 2.1 9.5 4.2 2.3 11.0 8.8 1.9 0.0 2.1 0.0 3.2 9.2 14.7 3.0 11.4 18.9 12.8 10.6 0.2 0.3 0.0 0.1 6.8 2.5 0.0 0.5 0.0 5.3 3.0 5.9 0.0 1.1 0.3 15.1 3.9 0.8 15.4 0.2 14.7 0.8 1.1 5.7 0.0 4.0 0.0 1.6 0.0 0.0 10.3 0.3 0.0 5.2 0.3 9.0 0.1 0.8 0.1 0.0 2.4 0.7 0.0 32.4 0.1 0.0 100.4 1.8 8.7 0.0 1.3 9.3 0.0 0.0 0.0 14.1 12.3 3.6 65.1 10.4 22.3 0.0 3.4 0.0 5.7 0.0 0.0 13.0 2.7 0.0 0.0 55.9 0.7 0.7 8.7 0.4 3.3 1.4 1.3 1.4 2.0 2.0 1.6 1.9 1.7 2.0 1.9 2.6 1.9 35.7 9.6 5.3 1.0 4.3 2.8 0.1 0.0 0.6 0.1 0.5 1.3 5.7 0.0 0.0 0.0 0.0 0.6 3.0 0.4 0.0 0.5 0.5 0.2 2.6 32.5 0.0 8.4 0.3 0.4 0.7 8.4 0.5 0.3 3.8 0.1 47.5 10.8 34.1 0.0 0.2 0.3 0.0 24.8 23.5 0.4 2.5 17.8 0.0 4.7 44.2 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.2 0.0 0.1 0.0 0.0 6.6 7.5 10.6 0.1 2.2 0.3 3.1 0.4 1.1 0.4 0.3 0.4 HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.3" "Cell type enhanced" "Detected in many" "Adipocytes: 33.8;Endothelial cells: 21.4;Fibroblasts: 22.2;Horizontal cells: 26.9;Microglial cells: 45.0" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 22.3;hTERT-RPE1: 20.1;MCF7: 76.5;SK-MEL-30: 50.2;WM-115: 43.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 9.9" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 9200000 "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" 9.7 1.4 1.3 0.6 1.2 0.0 8.4 0.9 1.1 3.7 1.3 9.0 0.9 1.9 2.5 5.4 1.8 6.5 8.4 0.8 1.1 2.5 7.8 20.3 0.4 1.5 1.9 3.9 0.9 0.9 3.2 4.8 1.5 7.5 2.8 0.6 7.7 1.4 4.8 4.1 3.1 4.3 1.4 8.4 1.7 2.6 1.7 0.8 3.2 7.0 2.4 1.8 3.8 0.9 0.2 0.1 1.6 0.0 4.7 4.7 0.0 0.5 0.9 0.3 0.5 0.0 0.1 1.9 0.2 22.3 1.6 5.0 0.1 0.2 0.1 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 4.7 0.0 5.6 0.4 20.1 2.8 0.0 0.2 0.0 0.0 76.5 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 50.2 4.5 0.1 0.0 0.0 13.7 1.3 0.0 5.1 0.2 0.0 0.3 2.7 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.3 1.2 0.9 1.1 0.8 1.1 1.5 1.9 1.5 1.4 1.7 0.9 33.8 3.2 7.0 0.3 0.0 3.2 0.2 4.9 2.2 1.7 1.2 1.8 2.8 0.0 0.8 0.0 0.0 0.1 0.2 0.3 0.0 0.0 8.3 0.6 1.5 21.4 0.0 0.0 1.1 0.0 0.8 22.2 0.0 0.9 0.0 5.2 7.9 1.9 0.1 26.9 3.8 0.0 0.0 0.3 2.8 2.7 3.7 0.4 5.4 45.0 0.0 0.1 0.0 3.0 1.5 0.0 0.0 2.2 1.2 0.1 0.0 0.2 1.0 0.0 0.0 2.5 7.7 0.5 0.1 0.4 1.7 0.0 0.4 0.1 0.0 0.2 HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119748002-119768905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 2434.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 327.2;Hepatocytes: 1118.3;Intestinal goblet cells: 226.8;Paneth cells: 177.7;Undifferentiated cells: 282.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 441.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 113.6;RT4: 201.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027423, HPA027442, CAB032906" Enhanced Approved Mitochondria NA NA 830000 "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "CAB032906: AB_2118322, HPA027423: AB_2672266, HPA027442: AB_2672277" "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "unprognostic (7.62e-2)" "unprognostic (1.49e-2)" "prognostic favorable (2.43e-7)" "unprognostic (9.68e-2)" "unprognostic (3.21e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "prognostic favorable (3.43e-5)" "unprognostic (9.57e-2)" "unprognostic (2.31e-1)" "unprognostic (5.00e-2)" "unprognostic (1.54e-3)" 1.0 0.3 0.0 7.3 0.0 0.0 222.4 0.0 0.0 0.1 5.2 366.7 165.6 1.4 0.4 4.3 0.4 4.3 36.6 0.0 0.1 64.9 2434.1 2.2 0.1 0.0 0.1 0.1 20.1 0.1 0.1 0.4 0.0 34.0 228.0 0.1 50.8 0.6 6.9 14.2 151.8 23.7 0.0 0.6 101.2 35.6 0.0 0.4 0.6 3.1 0.0 36.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 12.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 113.6 0.1 0.2 0.7 0.7 0.0 201.6 0.1 0.8 0.6 0.0 0.0 0.1 7.6 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 10.8 0.0 2.4 0.1 3.7 0.0 1.2 0.0 18.8 5.6 8.7 42.9 0.1 31.3 0.0 0.8 0.0 327.2 0.0 0.0 1.9 0.6 0.1 1.1 73.1 24.0 0.0 0.0 0.2 0.2 66.8 1.4 4.5 19.5 16.4 1118.3 0.2 0.0 0.0 226.8 0.0 26.1 0.7 3.9 1.5 0.2 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 177.7 0.0 0.0 6.3 12.4 0.9 0.0 0.0 6.6 0.0 0.1 0.4 0.5 1.9 0.3 9.4 2.2 0.1 282.3 26.5 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 515.3;Late spermatids: 2001.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB025464: , HPA040611: AB_10961034" "unprognostic (3.33e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.91e-4)" "unprognostic (2.74e-1)" "unprognostic (4.27e-2)" "unprognostic (6.23e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (7.74e-3)" "unprognostic (9.87e-2)" "prognostic favorable (8.98e-6)" "unprognostic (3.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (2.64e-1)" 63.0 51.3 43.7 23.2 51.9 18.3 55.7 56.9 55.2 47.1 36.2 41.0 34.8 35.8 22.5 84.5 35.9 26.9 149.9 47.7 50.0 71.2 109.5 46.6 33.2 55.8 49.2 25.6 39.7 38.6 43.8 17.9 57.1 34.5 25.1 22.5 44.1 14.1 37.9 44.4 42.6 22.7 44.7 67.8 100.2 152.2 54.3 24.3 41.9 32.3 36.3 33.2 49.0 53.5 82.9 38.2 20.5 45.6 65.8 31.5 33.8 53.9 26.5 48.3 43.7 48.3 55.5 36.9 64.0 55.7 34.6 51.5 75.4 126.9 48.4 51.5 48.4 27.5 35.2 63.3 43.7 56.8 44.4 48.7 41.7 55.7 37.6 37.9 83.7 46.9 44.7 18.1 44.5 114.3 48.7 58.4 34.2 81.1 35.7 54.3 33.7 84.4 72.3 51.8 34.4 19.4 43.1 95.1 66.4 33.9 58.2 36.3 91.7 25.7 39.9 120.3 30.1 24.3 30.0 78.0 16.5 52.5 35.2 87.6 37.1 252.6 166.3 46.5 142.1 69.8 153.8 168.5 73.6 66.8 145.5 151.6 125.1 99.0 35.7 39.2 155.4 142.3 43.7 51.9 56.9 55.2 47.7 50.0 55.8 49.2 57.1 44.7 54.3 53.5 33.8 35.3 41.5 7.8 37.2 54.8 35.7 73.5 19.4 29.3 26.4 29.1 70.6 32.9 54.5 36.8 20.9 75.3 59.8 70.7 129.1 79.7 515.3 38.6 30.9 53.4 31.8 14.3 23.0 90.7 69.6 39.4 89.7 53.3 19.7 38.8 75.0 93.0 67.2 28.6 21.6 37.6 85.5 23.9 52.9 2001.6 45.4 30.6 62.2 5.6 29.3 53.9 141.1 9.5 32.9 114.9 70.7 56.1 47.1 37.7 110.8 239.3 39.9 27.8 72.3 14.6 58.0 199.7 149.8 28.2 51.6 38.4 88.3 47.4 48.9 28.7 HOGA1 "C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2" ENSG00000241935 "4-hydroxy-2-oxoglutarate aldolase 1" Q86XE5 10 97584323-97612802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 51.8;liver: 54.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 35.8;Distal tubular cells: 29.4;Hepatocytes: 43.3;Late spermatids: 18.4;Proximal tubular cells: 98.0" "Group enriched" "Detected in many" 5 "liver cancer: 4.5;renal cancer: 9.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AN3-CA: 7.8;EFO-21: 9.7;Hep G2: 26.1;RPTEC TERT1: 31.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039466 Approved NA NA 16000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039466: AB_2676522" "unprognostic (6.44e-2)" "unprognostic (3.64e-2)" "unprognostic (7.50e-2)" "unprognostic (2.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.29e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-3)" "unprognostic (4.72e-1)" "unprognostic (2.37e-1)" "unprognostic (1.28e-1)" "unprognostic (6.80e-2)" "prognostic favorable (9.08e-4)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (2.94e-3)" "unprognostic (7.20e-4)" 4.1 8.3 5.8 0.2 7.4 0.4 1.9 9.3 5.0 0.7 11.4 0.2 0.3 1.1 3.7 1.0 2.0 2.5 21.1 4.4 6.5 51.8 54.8 1.4 0.3 8.2 9.2 0.2 15.3 5.7 3.6 0.1 8.3 1.1 0.1 0.8 1.7 2.1 3.4 1.5 0.3 0.5 7.3 0.4 0.2 0.9 7.9 0.3 1.8 12.1 0.2 0.4 0.9 10.3 0.3 3.7 0.1 7.8 1.5 0.3 0.1 0.1 0.2 0.0 0.0 3.0 0.2 0.3 9.7 0.2 0.5 2.6 0.0 0.2 0.1 0.1 4.0 0.1 1.4 26.1 1.1 0.2 0.1 0.3 0.7 0.1 0.1 1.9 0.4 0.1 0.0 0.4 0.6 1.6 0.1 0.1 0.2 0.2 0.0 0.1 0.6 0.4 31.5 0.6 0.6 1.0 0.1 1.3 0.5 0.2 2.8 0.0 0.2 0.8 0.2 0.3 0.2 0.5 0.9 0.1 2.0 0.1 0.1 0.6 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.1 0.4 0.2 0.2 1.0 0.2 0.2 0.3 0.2 0.1 5.8 7.4 9.3 5.0 4.4 6.5 8.2 9.2 8.3 7.3 7.9 10.3 0.0 0.0 0.0 7.2 1.5 0.1 0.7 0.5 1.8 0.4 0.1 0.4 6.0 35.8 0.2 9.2 0.0 0.1 0.0 0.1 29.4 5.9 3.8 1.8 0.1 0.0 0.0 0.0 1.3 0.2 0.0 0.2 0.0 0.5 0.0 0.1 0.4 43.3 0.1 1.7 1.2 0.0 0.0 1.3 0.0 18.4 0.0 0.8 1.8 1.0 0.0 2.0 0.0 1.5 12.3 0.5 0.1 0.0 0.0 0.1 0.0 98.0 3.2 0.3 0.0 4.5 0.9 0.0 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.2 HOMER2 "CPD, Cupidin, DFNA68, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2" ENSG00000103942 "Homer scaffold protein 2" Q9NSB8 15 82836946-82986153 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 226.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 215.9;Endometrial ciliated cells: 184.4;Glandular and luminal cells: 151.9" "Cancer enhanced" "Detected in many" "prostate cancer: 15.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 52.7;Karpas-707: 92.6;SCLC-21H: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040134, CAB079014" Uncertain Supported Supported Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "CAB079014: , HPA040134: AB_10795272" "unprognostic (7.34e-2)" "unprognostic (3.58e-2)" "unprognostic (5.75e-4)" "unprognostic (3.31e-3)" "unprognostic (4.85e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-2)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-1)" "unprognostic (8.16e-4)" "unprognostic (2.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.26e-1)" "unprognostic (4.45e-3)" 1.5 6.3 6.5 1.1 7.6 4.6 26.9 8.2 12.8 23.1 69.8 3.2 8.5 8.4 33.7 21.2 25.9 12.8 21.9 16.2 7.8 7.2 46.4 5.3 1.3 5.7 4.6 2.6 226.2 5.1 7.7 0.6 5.7 57.7 1.0 6.4 71.2 4.6 108.7 45.0 1.3 1.4 4.1 4.8 55.4 6.1 6.0 3.0 28.9 55.9 3.6 1.3 11.7 8.0 16.6 6.9 7.2 18.9 0.2 0.1 1.1 1.1 0.0 1.7 0.6 1.2 11.5 0.1 8.8 8.4 8.3 9.1 52.7 24.9 1.2 45.1 33.5 10.6 0.4 8.3 0.7 0.4 32.6 1.8 37.4 0.6 2.1 1.9 0.0 20.6 0.4 92.6 7.0 48.4 3.2 1.1 11.4 1.4 5.1 2.2 11.5 5.5 25.3 20.1 50.8 13.1 18.6 14.1 17.6 5.2 17.1 3.5 0.2 17.2 31.7 1.3 15.3 11.8 5.9 1.8 29.0 0.4 6.4 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.3 0.1 0.0 0.4 0.0 0.0 0.5 0.2 0.3 6.5 7.6 8.2 12.8 16.2 7.8 5.7 4.6 5.7 4.1 6.0 8.0 1.9 16.0 10.1 24.8 3.8 4.6 56.1 7.2 10.2 15.0 39.7 20.4 23.0 215.9 14.6 11.0 18.8 1.1 4.4 0.3 7.9 29.6 1.9 184.4 15.4 12.4 3.0 8.2 24.8 76.5 0.4 3.6 14.3 151.9 0.0 11.9 1.4 59.6 13.3 20.2 35.1 0.4 0.0 3.2 73.9 4.0 1.8 9.2 37.4 7.5 7.9 18.5 1.0 6.6 11.8 25.9 0.1 0.7 4.1 81.5 0.7 12.1 4.0 5.1 0.0 7.8 4.8 5.5 16.6 19.4 6.0 0.7 3.1 4.1 0.4 30.5 HOXA10 "HOX1, HOX1H" ENSG00000253293 "Homeobox A10" P31260 7 27170592-27180261 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 76.8;skeletal muscle: 76.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 174.0;Enteroendocrine cells: 68.1;Paneth cells: 32.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basophil: 10.7;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 10.7;NK-cells: 13.1" "Cell line enhanced" "Detected in many" "HEK 293: 179.0;THP-1: 96.7;U-937: 100.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 190 "spinal cord: 18.9" "CAB019384, HPA071918" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Nuclear bodies" "CAB019384: , HPA071918: " "unprognostic (4.98e-2)" "unprognostic (5.66e-2)" "unprognostic (1.93e-1)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (2.73e-3)" "unprognostic (2.61e-2)" "unprognostic (1.41e-2)" "unprognostic (8.05e-2)" "unprognostic (2.71e-2)" "unprognostic (3.83e-3)" "unprognostic (1.57e-1)" "unprognostic (7.13e-2)" "unprognostic (8.46e-3)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-2)" 13.4 6.8 0.0 6.1 0.0 4.3 6.8 0.0 0.0 40.8 0.0 32.6 0.1 76.8 9.1 0.2 8.3 0.1 0.0 0.0 0.0 13.7 0.1 0.1 2.3 0.0 0.0 0.8 0.0 0.0 0.0 13.4 0.0 26.3 13.2 0.0 0.0 15.4 76.4 6.0 7.9 44.9 0.1 0.2 0.1 0.3 0.0 5.2 0.1 0.0 0.2 20.4 17.2 0.1 20.6 4.3 0.0 59.9 29.3 28.0 0.2 40.1 27.2 18.0 16.8 6.1 17.8 0.0 10.9 31.6 0.0 22.6 15.5 0.0 13.2 9.5 179.0 21.6 15.0 0.5 0.8 9.6 31.4 17.8 0.9 1.5 0.0 0.0 27.5 6.3 0.9 0.0 13.3 0.0 0.0 63.1 0.0 16.6 18.8 1.9 4.0 0.1 34.7 9.6 46.7 0.1 13.8 0.0 0.1 6.4 0.1 96.7 0.0 0.0 16.1 21.1 0.2 0.4 0.1 0.0 0.0 100.4 0.5 10.7 0.1 0.3 2.2 0.0 0.0 0.1 0.0 0.2 1.2 0.3 0.0 0.0 0.0 13.1 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 5.5 0.0 0.0 0.0 0.2 3.7 10.0 0.0 0.6 0.0 4.4 4.6 1.6 0.0 0.0 7.3 0.0 0.5 4.5 28.8 19.6 0.0 0.0 3.1 174.0 5.4 68.1 15.5 0.0 0.0 0.4 13.3 0.0 2.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 25.0 0.0 2.5 4.7 0.0 0.0 2.0 5.4 0.0 0.5 0.0 7.2 0.0 0.0 0.0 32.1 0.4 1.3 18.1 18.8 27.1 0.0 0.0 0.0 13.3 15.7 2.3 4.6 0.5 4.1 0.5 3.1 0.0 25.5 10.1 HOXB8 "HOX2, HOX2D" ENSG00000120068 "Homeobox B8" P17481 17 48611377-48615292 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.1;epididymis: 48.1;kidney: 37.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 88.3;Distal tubular cells: 72.4;Endometrial ciliated cells: 21.3;Enteroendocrine cells: 44.1;Glandular and luminal cells: 26.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 33.3" "Region enhanced" "Detected in many" "spinal cord: 114.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.0;HDLM-2: 17.2;HEK 293: 36.9;LHCN-M2: 17.3;RPTEC TERT1: 35.3" "Region enriched" "Detected in single" 65 "pons and medulla: 6.5" "Region enriched" "Detected in all" 5 "spinal cord: 51.2" HPA075905 Supported Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA075905: AB_2686767" "unprognostic (4.44e-1)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (1.94e-2)" "unprognostic (9.07e-5)" "unprognostic (6.63e-3)" "unprognostic (1.40e-3)" "unprognostic (6.00e-2)" "unprognostic (5.66e-3)" "unprognostic (2.93e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.30e-7)" "unprognostic (1.77e-2)" "unprognostic (6.64e-2)" "unprognostic (4.57e-2)" "unprognostic (2.88e-3)" 7.2 7.2 0.1 1.5 0.0 0.0 2.7 0.0 0.0 10.7 0.0 4.7 0.0 2.8 48.1 0.0 1.4 0.0 0.0 0.0 0.0 37.6 0.0 0.4 0.0 36.4 0.0 0.1 0.1 0.8 0.1 0.3 1.8 1.0 1.2 0.0 0.0 20.8 0.4 0.5 7.1 1.5 114.1 0.1 6.6 1.0 0.0 0.0 0.1 0.0 0.0 3.7 0.7 20.8 2.1 5.3 0.0 0.8 0.7 1.0 0.8 0.0 0.0 0.0 0.0 0.3 0.8 0.0 34.0 5.3 0.6 0.0 0.1 0.0 0.0 17.2 36.9 1.0 0.1 0.0 0.3 0.0 5.5 1.1 0.0 0.1 0.0 0.7 2.1 0.2 11.6 0.0 17.3 0.0 0.0 0.4 0.0 11.3 0.0 0.0 3.6 0.1 35.3 1.0 0.0 0.1 0.6 0.0 5.4 0.1 0.4 0.0 8.8 0.0 1.6 0.1 0.7 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 36.4 0.0 1.8 114.1 0.0 20.8 4.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 88.3 0.0 0.0 0.1 1.8 72.4 0.0 0.3 21.3 2.1 2.6 44.1 0.0 0.0 0.0 0.8 0.3 0.0 26.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.2 0.0 0.0 0.7 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.2 2.7 8.9 0.0 0.0 0.0 0.1 0.8 2.3 9.2 0.0 0.0 0.0 0.3 0.0 5.0 0.0 HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 5.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Distal tubular cells: 1.9;Melanocytes: 3.6;Proximal enterocytes: 3.7;Spermatocytes: 3.5;Suprabasal keratinocytes: 3.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 34.7;BJ hTERT+: 17.5;HaCaT: 15.4;HeLa: 12.4;T-47d: 27.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 1.3" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 1.8 5.0 1.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 9.3 1.1 0.0 34.7 3.2 4.9 0.0 5.1 17.5 7.4 5.3 0.3 1.3 0.0 0.3 4.8 0.0 15.4 6.6 0.0 3.3 1.0 0.1 0.2 12.4 0.0 0.0 0.1 0.1 0.9 1.4 0.0 0.4 0.0 0.0 0.3 1.5 0.0 4.8 2.2 0.0 0.1 0.0 10.1 0.1 0.0 0.6 0.0 0.7 1.2 0.0 0.2 3.2 7.8 3.1 0.3 27.4 0.0 0.0 0.0 5.8 0.4 0.3 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.7 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.9 0.0 0.0 0.0 1.0 1.0 3.5 0.9 0.0 3.8 0.0 0.1 0.0 0.2 0.0 HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Breast myoepithelial cells: 3.0;Spermatogonia: 1.2;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 31.2;HaCaT: 66.1;SK-BR-3: 36.0;T-47d: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA051634 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.7 10.5 0.0 31.2 0.5 0.0 18.4 1.9 4.4 2.8 1.5 2.7 0.5 0.0 0.4 0.0 2.0 66.1 8.0 2.1 1.6 0.0 6.4 0.0 8.4 0.0 0.0 0.0 6.6 0.0 15.4 0.0 6.0 0.0 0.0 0.1 11.8 0.0 11.5 20.1 0.0 0.0 0.3 6.6 2.7 0.0 0.4 0.0 0.0 6.0 0.0 0.0 10.4 36.0 4.9 7.4 28.1 0.1 0.0 0.1 13.1 0.2 4.2 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.7 3.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 2.4 0.1 0.0 0.0 0.0 0.0 HOXC4 "HOX3, HOX3E" ENSG00000198353 "Homeobox C4" P09017 12 54016931-54056030 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 9.1;Endometrial ciliated cells: 12.3;Granulosa cells: 10.5;Sertoli cells: 6.6;Squamous epithelial cells: 8.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.4" "Region enhanced" "Detected in many" "medulla oblongata: 16.7;pons: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 23.8;HDLM-2: 31.2;HEK 293: 33.0;SH-SY5Y: 27.3" "Region enriched" "Detected in single" 24 "pons and medulla: 9.4" "Group enriched" "Detected in some" 49 "medulla oblongata: 4.9;pons: 3.7;spinal cord: 6.0" HPA053910 Supported Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA053910: AB_2682305" "unprognostic (2.78e-2)" "unprognostic (8.51e-2)" "unprognostic (2.96e-6)" "unprognostic (3.30e-2)" "unprognostic (6.27e-2)" "unprognostic (1.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-3)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (8.83e-3)" "unprognostic (4.37e-2)" "unprognostic (7.81e-2)" "unprognostic (8.43e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-4)" "unprognostic (9.82e-2)" 8.6 4.5 0.1 2.1 0.1 0.1 5.2 0.1 0.2 1.0 0.1 2.1 1.1 4.7 7.2 8.1 27.0 0.4 0.5 0.2 0.2 13.5 0.1 0.8 3.6 16.7 1.1 11.1 0.3 0.1 0.1 6.3 16.2 1.6 0.2 0.0 0.3 0.9 9.1 6.2 6.8 4.8 6.4 1.8 5.2 3.3 0.3 0.4 1.0 0.0 1.9 0.7 0.8 3.7 5.3 5.1 0.0 23.8 9.4 4.9 0.0 2.4 2.5 2.4 1.7 0.2 4.3 20.5 0.2 18.5 0.1 4.7 0.4 0.6 1.5 31.2 33.0 0.2 2.9 0.0 1.1 2.5 0.7 12.5 2.3 13.7 2.4 0.0 0.3 6.7 1.1 0.0 8.9 0.3 2.8 0.5 0.1 0.9 0.1 6.7 7.2 0.0 10.2 0.0 0.0 27.3 3.8 1.2 13.7 1.1 18.0 1.2 0.0 12.0 6.9 1.0 12.8 5.3 6.0 10.6 0.7 2.3 12.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.2 16.7 1.1 16.2 6.4 0.3 3.7 1.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 9.1 0.0 1.4 3.4 0.5 0.0 0.0 0.0 0.0 0.1 3.9 0.0 1.9 0.0 4.1 12.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 3.3 2.6 0.1 0.0 10.5 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.0 2.9 3.1 0.2 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.1 0.0 1.5 3.7 0.0 0.1 2.9 0.0 0.0 6.6 3.9 3.6 2.7 0.5 8.2 0.0 0.3 1.6 2.7 0.1 0.0 HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 9 "Hepatocytes: 1373.6;Proximal tubular cells: 2144.0" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cell line enriched" "Detected in some" 31 "Hep G2: 516.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" 2.3 5.3 0.6 0.7 0.4 0.9 4.6 3.2 0.6 2.0 119.0 1.2 0.1 4.1 0.7 0.7 6.4 1.1 3.5 7.8 0.5 531.0 2530.4 2.0 0.3 1.5 1.0 4.7 3.9 0.1 1.1 0.3 0.8 2.3 0.5 0.3 0.2 7.3 2.2 0.2 0.9 1.4 0.6 2.3 1.9 10.2 3.5 0.1 0.7 0.1 0.1 3.7 1.9 1.0 0.3 0.9 0.6 0.6 0.3 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.5 0.2 0.6 1.1 0.2 0.4 0.2 0.0 0.0 0.3 0.8 1.2 5.4 516.4 11.5 1.8 16.4 3.6 0.3 0.0 0.0 1.3 0.0 0.5 0.8 0.0 1.3 1.3 0.2 0.4 9.9 0.4 0.0 0.3 1.6 0.5 0.0 1.4 0.1 0.1 1.5 0.1 0.1 6.9 1.1 0.9 0.2 0.0 0.3 0.1 0.1 0.8 0.6 0.7 0.2 1.2 0.0 0.0 0.6 7.8 0.0 0.8 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 3.9 0.0 1.3 3.8 0.0 0.3 0.6 0.4 3.2 0.6 7.8 0.5 1.5 1.0 0.8 0.6 3.5 1.0 0.0 0.0 0.0 0.7 15.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 55.8 0.0 92.0 0.0 0.8 0.0 0.0 193.7 0.5 38.0 0.1 0.0 2.6 0.0 80.2 1.0 16.2 0.3 0.4 0.0 0.1 0.0 0.0 38.9 1373.6 0.3 0.0 1.0 0.0 0.0 37.8 0.3 121.0 2.5 10.8 0.0 0.0 0.4 0.0 0.0 1.5 0.7 0.2 0.0 5.3 0.0 0.0 0.0 2144.0 0.0 0.0 0.0 2.0 0.2 1.8 1.4 0.0 0.0 1.1 8.0 7.1 0.0 0.0 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 6 "Hepatocytes: 442.2;Proximal tubular cells: 201.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 31.5;Hep G2: 47.8;T-47d: 22.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 1.8 0.9 5.6 0.2 8.8 0.0 11.6 7.0 7.2 1.6 4.2 1.1 1.4 4.0 3.9 0.3 7.4 4.0 5.1 5.7 6.5 200.5 866.2 11.8 0.4 7.5 8.1 1.3 272.1 24.2 14.8 0.5 7.5 20.1 0.3 0.3 15.6 4.7 22.1 0.9 1.1 0.2 6.5 2.6 58.2 1.3 7.6 0.2 19.9 5.4 0.1 0.6 0.4 11.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.5 0.0 0.1 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.3 0.1 0.0 0.0 3.2 0.2 0.1 0.0 0.2 0.5 22.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.8 7.0 7.2 5.7 6.5 7.5 8.1 7.5 6.5 7.6 11.7 0.5 9.6 32.4 8.8 3.0 0.1 5.1 0.0 0.0 7.2 12.0 8.9 3.4 51.5 1.3 33.1 0.0 0.1 0.0 0.1 52.8 7.5 8.9 4.9 1.0 1.1 2.4 10.7 2.3 26.5 0.3 1.9 18.3 12.5 2.5 0.1 8.6 442.2 1.1 0.0 1.7 2.4 0.0 9.7 0.3 26.0 0.0 1.8 0.0 2.8 0.6 1.6 0.0 0.0 41.6 14.4 0.0 0.4 0.0 7.5 0.0 201.0 0.0 0.6 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.8 1.8 0.1 0.1 0.5 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HPX ENSG00000110169 Hemopexin P02790 11 6431049-6442617 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 908 "liver: 5440.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 6095.8" "Cancer enriched" "Detected in many" 79 "liver cancer: 571.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "Hep G2: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016725, HPA065318, HPA068847" Approved "Secreted to blood" NA NA 425000000000 190000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016725: , HPA065318: , HPA068847: " "unprognostic (3.39e-2)" "unprognostic (9.26e-2)" "unprognostic (3.88e-1)" "unprognostic (6.19e-4)" "unprognostic (2.05e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.26e-4)" "unprognostic (6.33e-2)" "unprognostic (5.67e-3)" "unprognostic (3.88e-1)" "unprognostic (5.08e-3)" "unprognostic (2.78e-2)" "unprognostic (5.82e-12)" "unprognostic (2.01e-1)" "unprognostic (4.48e-1)" "unprognostic (1.84e-2)" "unprognostic (2.14e-2)" 1.1 0.8 0.8 0.1 0.7 0.1 5.9 1.0 1.0 1.6 0.6 1.2 0.4 1.0 0.2 0.5 1.6 0.3 0.9 0.7 0.7 1.4 5440.6 1.2 0.3 0.7 0.7 1.6 5.5 0.1 1.2 0.3 0.7 2.4 0.6 1.7 1.1 0.6 0.3 1.6 1.1 0.3 0.6 3.8 0.9 1.1 0.8 0.1 0.9 0.0 0.1 1.1 1.2 0.7 0.2 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.3 1.3 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.6 0.2 21.3 0.0 3.0 0.0 0.8 0.6 0.1 0.0 0.5 0.1 0.2 0.4 0.1 0.1 0.4 0.0 0.0 0.3 0.9 0.0 0.1 1.3 0.2 0.0 0.1 0.2 0.0 1.0 3.0 0.2 0.2 1.1 0.0 0.5 0.3 0.2 1.0 0.1 0.4 0.2 0.9 0.2 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 1.0 1.0 0.7 0.7 0.7 0.7 0.7 0.6 0.8 0.7 0.5 3.2 0.5 0.3 15.1 0.6 0.2 0.2 0.0 1.5 19.1 7.7 0.7 80.1 0.2 0.0 2.1 0.1 0.1 0.6 0.0 0.1 2.3 0.2 0.3 6.2 0.0 157.7 0.7 0.6 0.1 0.4 0.0 1.2 0.0 1.1 132.8 6095.8 0.2 0.0 0.8 0.7 0.0 155.3 0.2 2.9 0.3 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.7 0.2 0.0 1.0 2.1 0.0 0.4 0.5 0.6 0.5 0.0 0.3 0.0 11.3 0.2 0.5 0.3 HSBP1L1 "FLJ10967, MGC189743" ENSG00000226742 "Heat shock factor binding protein 1 like 1" C9JCN9 18 79964582-79970822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 31.9;T-cells: 26.0" "Cell line enhanced" "Detected in many" "HHSteC: 162.8;SK-MEL-30: 100.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048273 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA048273: AB_2680337" "unprognostic (2.08e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (5.85e-2)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (8.15e-3)" "unprognostic (8.86e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.53e-3)" "unprognostic (7.41e-2)" "unprognostic (4.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.12e-1)" "unprognostic (8.28e-2)" "unprognostic (1.76e-2)" 9.6 17.4 18.4 2.9 17.8 2.9 9.6 19.9 26.4 10.0 23.4 16.0 6.7 7.6 11.1 17.4 8.7 5.7 6.7 17.2 18.1 18.6 29.7 10.7 4.2 19.1 18.5 6.6 20.4 19.7 6.7 9.9 19.6 10.2 13.1 14.8 12.8 7.6 12.5 16.0 6.5 5.7 18.1 5.2 10.1 0.8 20.3 4.3 8.9 10.6 4.9 6.2 10.6 17.2 32.2 8.6 0.3 0.5 4.6 15.4 12.7 14.3 32.2 14.8 13.0 16.5 21.7 0.0 3.6 18.8 0.2 18.3 28.5 18.9 7.0 30.6 6.7 0.0 8.8 9.6 162.8 0.0 0.0 18.0 49.6 1.7 10.8 31.5 0.3 4.8 0.0 0.0 0.7 26.8 0.1 0.0 0.0 17.6 30.1 0.3 0.0 0.0 53.7 7.6 0.5 1.8 15.2 20.9 100.2 1.4 11.9 7.6 0.0 0.1 0.0 0.4 0.1 0.0 16.7 0.0 0.2 8.9 0.6 31.9 6.8 8.6 5.8 4.4 6.9 2.2 10.1 6.2 2.8 2.5 26.0 14.0 0.4 5.2 1.6 3.3 4.9 6.2 18.4 17.8 19.9 26.4 17.2 18.1 19.1 18.5 19.6 18.1 20.3 17.2 36.4 54.5 34.5 12.1 5.0 39.8 66.0 135.5 67.2 12.0 89.8 93.6 12.4 48.6 109.2 49.7 22.9 126.6 9.6 119.8 68.4 63.8 1.3 47.2 13.2 23.0 11.5 11.4 5.7 62.1 67.1 16.0 31.6 59.4 19.0 37.2 30.0 122.5 44.7 20.2 11.0 81.3 71.2 20.5 18.0 1.3 19.9 16.0 39.2 6.5 4.0 33.2 6.2 1.0 3.1 137.3 99.6 24.5 2.3 80.2 70.6 80.6 80.3 33.0 0.0 6.3 15.9 1.3 1.3 46.8 57.8 117.4 12.2 34.5 99.6 104.4 HSD17B4 "DBP, MFE-2, SDR8C1" ENSG00000133835 "Hydroxysteroid 17-beta dehydrogenase 4" P51659 5 119452473-119637199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Oxidoreductase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 320.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.1;Oligodendrocytes: 221.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 75.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021302, HPA021311, HPA021479" Enhanced Enhanced Peroxisomes NA NA 450000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Peroxisomes "HPA021302: AB_1844350, HPA021311: AB_1844351, HPA021479: AB_1844352" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.21e-2)" "unprognostic (1.24e-2)" "unprognostic (3.12e-2)" "unprognostic (2.83e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "prognostic favorable (6.31e-6)" "unprognostic (1.60e-1)" "unprognostic (8.26e-2)" "unprognostic (1.80e-1)" "unprognostic (6.65e-3)" 74.4 85.0 37.2 41.9 50.2 19.7 44.4 51.1 50.0 68.8 47.2 64.5 79.3 34.1 53.0 50.9 39.1 52.5 68.6 34.9 50.7 84.4 320.0 75.6 33.2 50.6 49.5 34.8 55.2 75.5 26.5 53.4 49.2 56.8 65.9 27.2 44.9 79.0 59.8 51.8 87.6 39.5 44.7 36.6 53.8 20.9 49.9 31.9 133.9 52.8 39.7 57.7 31.5 56.3 68.8 59.8 104.1 143.7 261.8 120.3 57.9 63.4 80.3 57.3 103.0 49.4 112.8 84.4 128.0 70.6 81.0 68.7 77.0 144.4 84.3 94.6 79.8 118.1 62.0 96.9 65.8 38.0 169.9 110.0 56.3 64.9 54.7 69.3 103.9 59.4 41.0 48.9 64.2 64.0 59.2 23.6 82.1 161.1 43.1 68.7 103.0 104.8 92.2 192.7 81.1 70.6 149.0 23.4 78.7 93.3 88.7 68.2 67.6 52.7 38.1 66.5 53.1 26.3 55.3 32.6 63.7 104.4 56.7 75.5 27.3 49.9 6.5 15.5 7.3 11.1 5.8 5.3 21.3 10.3 5.5 5.2 4.9 6.9 17.1 13.8 4.1 12.2 37.2 50.2 51.1 50.0 34.9 50.7 50.6 49.5 49.2 44.7 49.9 56.3 38.9 73.7 125.2 47.3 28.2 14.9 42.5 43.2 24.5 19.7 31.1 22.1 76.4 64.3 52.3 36.8 14.6 64.3 19.1 40.0 84.1 39.9 8.8 29.0 48.9 32.3 33.0 42.1 92.9 35.8 29.3 35.6 48.4 35.8 68.4 25.3 32.2 225.1 77.9 15.2 102.8 45.8 22.4 51.8 13.8 13.4 34.5 46.7 8.8 49.6 85.7 47.3 9.2 78.4 221.5 20.5 29.6 51.1 23.1 24.8 85.7 65.4 33.8 18.6 6.6 29.2 32.2 30.6 22.7 34.7 17.2 65.0 15.7 57.2 55.3 39.7 HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 181.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 214.8;Early spermatids: 153.9;Granulosa cells: 187.2;Late spermatids: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA042890: AB_2678216, HPA050453: AB_2681131" "unprognostic (3.17e-3)" "unprognostic (1.62e-2)" "unprognostic (1.90e-3)" "prognostic favorable (9.23e-6)" "unprognostic (3.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.82e-1)" "prognostic favorable (9.29e-7)" "unprognostic (1.44e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (7.35e-2)" 76.3 63.6 28.1 13.3 30.1 11.6 22.8 25.1 29.5 23.3 27.6 31.7 38.9 22.8 11.5 29.8 21.2 19.0 89.9 24.8 33.1 69.0 149.0 28.7 13.9 25.4 33.2 50.8 20.0 21.8 8.8 16.8 27.1 20.3 26.9 12.6 18.8 15.9 151.7 31.1 32.2 20.5 26.6 18.6 24.6 14.0 32.0 19.6 30.4 181.3 15.8 29.2 15.0 28.5 45.0 39.4 29.0 14.8 49.0 48.4 33.4 30.1 18.6 21.1 17.7 77.0 49.4 28.5 16.2 44.4 26.9 50.6 31.9 42.2 25.8 120.9 21.0 30.0 58.5 76.1 30.7 17.1 18.5 52.0 29.9 31.3 22.8 30.5 24.8 34.7 42.3 18.9 58.2 29.6 42.5 15.3 17.2 106.9 50.3 27.1 87.4 42.7 44.5 40.4 20.7 14.5 75.8 49.5 26.0 23.7 70.0 20.0 28.3 30.2 27.9 85.2 29.6 21.5 57.3 13.5 37.0 24.8 18.2 54.3 8.4 32.8 4.6 8.1 6.8 6.9 4.8 5.0 9.5 8.4 5.6 5.9 48.0 5.9 11.5 9.4 8.7 4.9 28.1 30.1 25.1 29.5 24.8 33.1 25.4 33.2 27.1 26.6 32.0 28.5 32.0 99.3 84.3 48.6 14.1 13.3 17.5 21.6 29.6 9.3 12.0 13.3 214.8 14.3 32.2 14.7 6.2 26.5 18.3 23.7 64.6 15.5 153.9 38.6 38.3 19.1 14.9 32.8 10.8 18.7 30.9 31.1 29.0 27.8 30.4 187.2 17.2 124.2 35.7 6.7 12.2 32.2 8.2 23.6 12.5 163.0 27.4 27.5 8.8 15.9 47.3 24.1 6.2 16.1 19.3 13.2 23.5 47.0 20.9 16.0 52.4 111.1 37.7 14.5 46.0 18.1 46.9 12.9 16.4 34.2 16.2 31.7 16.2 108.9 36.2 29.5 HSPA12A "FLJ13874, KIAA0417" ENSG00000165868 "Heat shock protein family A (Hsp70) member 12A" O43301 10 116671192-116850251 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 205.0;Inhibitory neurons: 186.4;Leydig cells: 63.3;Peritubular cells: 68.4;Theca cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "memory B-cell: 1.3;naive B-cell: 1.7;T-reg: 1.0" "Group enriched" "Detected in many" 14 "B-cells: 1.7;T-cells: 1.0" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011273, HPA073244" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cytosol" "HPA011273: AB_1851190, HPA073244: AB_2686586" "unprognostic (7.93e-2)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (2.25e-2)" "unprognostic (1.44e-1)" "unprognostic (7.31e-3)" "unprognostic (5.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.32e-1)" "unprognostic (3.62e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (2.85e-2)" "unprognostic (1.66e-1)" "unprognostic (3.75e-1)" "unprognostic (5.55e-4)" 15.8 21.9 10.9 1.5 13.5 0.0 8.8 11.2 28.2 13.7 7.9 12.4 0.7 9.2 12.5 3.9 10.3 2.3 9.6 16.6 11.1 17.4 1.6 3.0 2.7 17.3 12.2 20.5 2.7 20.0 7.9 0.8 16.4 5.6 1.9 11.0 2.6 5.5 4.9 5.7 4.1 4.6 2.7 3.8 4.7 6.2 27.3 2.1 9.4 3.4 2.8 7.9 10.0 14.7 8.0 10.0 0.1 7.1 6.6 4.4 0.1 5.5 10.1 1.9 1.0 10.0 2.8 0.0 4.1 7.6 5.2 6.1 8.4 0.7 4.9 0.0 3.2 0.0 0.8 5.5 1.9 0.0 1.0 1.7 6.6 7.3 0.9 13.9 0.0 3.3 0.0 0.0 2.1 4.0 0.0 0.0 1.2 0.0 0.1 0.0 1.0 1.2 22.1 1.8 5.3 12.7 4.0 2.9 3.0 2.4 3.2 0.0 0.0 1.4 5.5 12.3 10.2 0.1 3.2 0.0 3.9 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 10.9 13.5 11.2 28.2 16.6 11.1 17.3 12.2 16.4 2.7 27.3 14.7 2.1 6.4 3.6 27.7 1.0 11.1 1.6 0.5 2.8 35.8 5.2 6.9 7.8 2.8 2.0 12.9 22.9 0.1 0.1 1.6 15.6 4.2 4.4 12.5 16.1 3.1 0.0 0.0 205.0 3.5 0.1 17.8 0.0 4.4 0.0 2.4 2.9 0.4 0.1 30.3 186.4 0.3 0.0 0.0 5.2 9.7 63.3 0.5 26.6 9.4 0.0 35.8 0.0 27.6 54.8 2.4 0.0 68.4 0.1 2.1 0.0 25.4 11.3 10.2 13.1 14.7 14.9 1.0 5.2 0.5 5.1 0.3 0.8 82.0 0.3 0.7 HSPA12B "C20orf60, dJ1009E24.2" ENSG00000132622 "Heat shock protein family A (Hsp70) member 12B" Q96MM6 20 3732685-3753111 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 65.0;Endothelial cells: 50.1;Hepatic stellate cells: 16.1;Late spermatids: 16.8;Microglial cells: 15.0;Peritubular cells: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.9;EFO-21: 4.9;HUVEC TERT2: 9.5;TIME: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013659, HPA015639" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA013659: AB_1234541, HPA015639: AB_1851192" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (6.99e-2)" "unprognostic (4.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.21e-1)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.07e-2)" "unprognostic (6.45e-2)" "unprognostic (8.74e-2)" "unprognostic (2.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (4.05e-1)" "unprognostic (1.66e-2)" 23.1 4.1 9.3 3.0 8.9 1.3 23.0 6.6 7.8 15.0 4.2 6.6 1.8 12.5 1.2 4.2 10.3 4.7 29.3 6.6 7.0 11.8 1.7 20.6 1.7 8.2 7.9 8.2 2.6 1.5 2.9 11.3 8.4 4.9 1.2 0.4 5.4 1.9 12.3 7.7 6.1 4.0 6.8 25.3 5.1 5.2 10.4 0.7 9.2 10.2 0.9 10.2 10.2 6.0 0.5 1.7 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.2 4.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 2.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 1.4 9.5 0.4 0.3 0.2 0.0 1.0 0.4 0.9 1.0 0.0 0.8 1.8 0.2 0.5 0.0 0.0 0.9 0.7 0.3 0.2 0.1 0.1 0.2 0.5 5.3 0.1 2.2 0.7 0.4 0.4 0.3 0.5 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 9.3 8.9 6.6 7.8 6.6 7.0 8.2 7.9 8.4 6.8 10.4 6.0 65.0 0.0 0.0 0.3 0.4 1.9 0.1 0.0 0.0 0.5 0.7 0.3 5.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.8 0.2 3.2 50.1 0.0 0.0 0.5 0.0 0.2 10.5 0.0 0.1 0.0 0.1 16.1 0.3 0.5 0.0 0.4 0.0 0.0 1.4 2.5 16.8 7.5 0.2 0.0 15.0 0.0 3.1 0.0 0.0 0.3 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.2 2.0 3.5 1.7 0.3 1.1 0.4 0.3 0.7 0.0 0.2 HSPA4L "APG-1, HSPH3, Osp94" ENSG00000164070 "Heat shock protein family A (Hsp70) member 4 like" O95757 4 127781821-127840733 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.7" "Cell type enhanced" "Detected in many" "Early spermatids: 436.6;Late spermatids: 901.8;Spermatocytes: 203.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.1" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "HAP1: 82.3" "Low region specificity" "Detected in all" "CAB034450, HPA039149, HPA061446" Enhanced Approved Centrosome,Cytosol NA NA 1000000 "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Centrosome, Cytosol" "CAB034450: AB_2119823, HPA039149: AB_2676366, HPA061446: AB_2684520" "unprognostic (6.66e-2)" "unprognostic (2.39e-1)" "unprognostic (5.33e-2)" "unprognostic (9.40e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (1.23e-3)" "unprognostic (2.41e-1)" "unprognostic (3.90e-1)" "unprognostic (2.38e-4)" "unprognostic (1.40e-2)" "unprognostic (3.28e-1)" "prognostic favorable (3.80e-9)" "unprognostic (8.53e-2)" "unprognostic (1.56e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (6.78e-4)" 1.3 11.3 12.0 1.0 10.5 3.0 3.5 21.7 30.6 3.5 13.5 2.6 2.3 1.0 1.2 13.7 7.0 3.7 6.4 10.6 32.7 13.3 7.4 1.5 0.3 15.2 17.7 3.8 4.0 11.1 8.0 2.9 21.5 4.1 3.5 26.9 5.7 4.9 1.5 8.4 1.2 3.0 12.9 0.9 2.1 108.7 17.7 4.0 3.9 3.6 4.7 2.8 7.7 15.9 20.6 26.5 14.0 22.1 9.5 9.5 16.2 9.1 3.7 8.6 9.5 19.7 9.2 0.1 16.4 2.6 7.0 4.7 82.3 32.9 11.7 38.7 24.7 11.0 33.5 23.7 3.5 42.3 17.9 8.7 29.7 5.7 20.3 8.9 11.3 9.4 19.8 12.2 10.9 14.9 13.6 3.7 3.3 21.5 21.6 0.1 1.5 2.0 29.1 9.2 25.7 9.4 16.4 28.2 1.5 8.3 21.7 7.1 3.2 3.0 0.1 3.7 22.1 23.6 29.3 6.4 11.7 28.3 9.4 0.6 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.0 10.5 21.7 30.6 10.6 32.7 15.2 17.7 21.5 12.9 17.7 15.9 2.7 3.2 9.3 17.6 1.1 28.4 91.9 31.3 40.9 57.7 7.7 9.4 18.1 12.8 27.6 9.2 104.3 10.0 0.8 3.4 19.6 6.8 436.6 17.8 1.6 6.8 18.4 0.0 47.1 2.9 2.1 8.1 2.6 5.2 15.8 2.5 1.8 9.7 1.2 40.4 70.4 3.5 24.4 2.5 9.7 901.8 10.2 4.7 8.8 7.5 3.0 16.6 2.1 19.6 9.3 2.8 0.3 9.8 0.4 26.2 0.3 24.6 52.0 66.8 0.0 18.7 12.5 203.1 13.5 47.5 42.5 16.7 4.2 2.8 5.3 65.2 HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Hydrolase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 2455.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Approved Nucleoplasm,Vesicles NA Yes 140000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Vesicles "CAB002056: , HPA052504: AB_2681854" "unprognostic (2.28e-3)" "unprognostic (1.19e-3)" "prognostic favorable (6.14e-6)" "unprognostic (1.75e-1)" "unprognostic (1.84e-2)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.65e-3)" "unprognostic (3.82e-1)" "unprognostic (9.64e-2)" "unprognostic (2.93e-1)" "unprognostic (3.22e-1)" "prognostic favorable (3.81e-4)" "unprognostic (2.53e-1)" "unprognostic (1.83e-1)" "unprognostic (2.74e-1)" "unprognostic (7.16e-2)" 539.8 604.9 456.3 542.1 498.1 442.4 448.9 591.6 887.9 326.6 571.4 435.8 506.9 367.3 614.7 554.2 498.5 508.6 892.4 535.1 614.9 850.5 763.2 480.1 685.0 564.8 564.2 421.4 1238.1 593.8 501.9 487.1 620.0 411.2 525.8 531.5 404.1 439.8 1519.0 224.4 453.5 508.4 554.2 520.3 676.7 395.0 559.8 628.6 422.6 1508.5 879.6 866.0 302.4 656.8 1369.6 2077.3 1370.5 1176.5 1259.4 1337.4 1775.6 2730.9 1550.4 3373.2 2004.8 3151.7 1787.3 2318.5 1614.6 1591.9 2337.3 1835.9 4091.6 1027.2 3323.5 1955.4 605.9 2570.4 881.5 1532.0 347.5 2418.0 1757.1 721.8 1594.5 1045.0 320.7 1753.4 1845.6 321.7 2727.8 1147.0 2704.5 1235.5 2507.0 1761.3 2063.2 3463.3 1874.0 2214.4 962.2 1281.3 1665.1 1008.4 1371.8 1023.9 1980.4 2110.5 763.6 1491.1 1837.1 901.9 1767.0 1621.1 1246.1 1404.5 2402.7 740.6 1985.0 1890.9 1791.1 3316.9 1970.0 517.7 592.3 587.8 1245.4 1159.8 1499.6 1009.2 1441.8 1366.1 656.1 752.2 1367.5 1326.5 201.8 1110.7 1255.0 465.5 1761.7 3439.4 456.3 498.1 591.6 887.9 535.1 614.9 564.8 564.2 620.0 554.2 559.8 656.8 795.5 192.3 228.2 72.5 576.3 282.3 2455.6 315.3 507.6 206.7 454.5 380.1 396.3 278.8 352.8 130.6 127.2 926.1 740.3 513.1 528.3 589.0 49.8 404.1 380.1 512.8 519.8 551.7 33.4 628.8 1032.6 609.7 366.0 366.5 434.8 633.8 249.9 223.9 810.9 181.7 45.6 511.1 303.2 359.8 1060.8 58.2 222.4 590.6 528.3 35.6 530.9 307.4 639.5 28.1 50.3 513.8 552.1 270.0 573.6 779.5 823.0 1002.2 465.7 278.1 243.3 416.3 893.1 248.9 419.2 590.6 284.6 1512.1 1123.5 430.3 632.0 1171.5 HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2969.8;tongue: 1759.1" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 165.7;Fibroblasts: 125.2;Leydig cells: 271.8;Peritubular cells: 220.4;Smooth muscle cells: 102.6;Theca cells: 311.0" "Cancer enhanced" "Detected in all" "stomach cancer: 93.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1774.3;ASC TERT1: 742.0;HHSteC: 599.9;HSkMC: 700.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nucleoli,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 310000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoli, Golgi apparatus" "CAB001974: , HPA044153: AB_2678836, HPA054811: AB_2682610" "unprognostic (3.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.21e-3)" "unprognostic (7.02e-2)" "unprognostic (9.67e-2)" "unprognostic (7.57e-2)" "unprognostic (1.18e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.32e-2)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.43e-6)" 650.0 414.0 37.3 45.4 40.6 0.4 394.9 32.5 49.2 581.9 26.1 699.9 28.1 565.1 101.6 112.3 495.1 97.9 1463.9 30.0 43.6 69.0 42.3 126.6 5.7 76.7 48.5 455.2 50.5 4.2 17.5 40.2 73.7 271.2 44.0 21.1 115.9 194.7 2969.8 39.1 180.0 278.2 50.8 15.7 362.1 60.6 53.8 6.2 99.5 1759.1 2.7 537.3 290.6 49.3 0.6 0.7 2.1 2.5 1774.3 742.0 1.2 83.0 1.3 4.9 9.3 1.1 0.4 0.7 0.6 252.4 0.0 0.2 0.4 0.7 3.9 0.9 0.5 0.4 1.3 0.5 599.9 0.2 0.9 700.3 0.0 19.1 0.9 2.2 5.4 0.3 0.5 1.0 0.2 0.3 0.4 1.9 1.2 2.3 0.6 1.5 0.5 0.7 0.0 0.1 0.8 0.7 0.1 0.2 0.7 0.3 0.3 0.5 0.1 153.2 0.9 17.3 0.6 1.0 2.8 0.3 20.5 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.3 40.6 32.5 49.2 30.0 43.6 76.7 48.5 73.7 50.8 53.8 49.3 11.1 3.2 0.6 1.6 0.1 1.8 0.4 0.0 3.4 7.8 0.5 0.5 29.7 0.0 0.0 0.0 0.0 2.5 0.1 0.1 0.0 0.1 27.0 4.9 165.7 3.6 0.0 5.2 0.2 0.0 2.5 125.2 4.1 3.5 0.0 3.6 17.5 0.3 5.0 0.0 0.5 0.0 0.0 0.3 3.6 18.9 271.8 2.7 1.8 0.0 0.6 44.5 0.0 0.0 0.1 0.2 0.0 220.4 0.1 0.4 0.0 0.4 0.0 2.8 26.3 38.0 102.6 2.3 1.4 1.9 2.0 4.8 1.8 311.0 0.0 0.5 HSPB7 cvHSP ENSG00000173641 "Heat shock protein family B (small) member 7" Q9UBY9 1 16014028-16019594 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 4135.3;skeletal muscle: 2417.8;tongue: 1229.5" "Cell type enriched" "Detected in some" 32 "Cardiomyocytes: 2389.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "fHDF/TERT166: 315.1" "Not detected" "Not detected" HPA027639 Approved Approved Nucleoplasm NA NA 130000 "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA027639: AB_10601756" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.28e-3)" "unprognostic (7.44e-3)" "unprognostic (8.35e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (1.02e-1)" "unprognostic (5.32e-2)" "unprognostic (2.47e-3)" "unprognostic (3.19e-3)" "unprognostic (6.94e-2)" "unprognostic (1.55e-1)" "unprognostic (1.20e-2)" "unprognostic (1.18e-2)" "unprognostic (1.51e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (1.26e-4)" 306.8 123.4 3.9 32.1 4.4 0.2 119.7 8.8 5.1 49.6 8.6 138.3 5.1 179.5 7.5 44.2 64.8 18.7 4135.3 4.1 5.6 38.5 3.2 22.1 1.7 13.1 7.9 25.4 9.2 38.8 5.3 7.1 12.0 43.0 8.0 3.1 35.1 24.4 2417.8 19.3 34.0 189.2 5.3 4.5 71.4 20.2 4.7 0.6 14.1 1229.5 0.7 99.2 30.5 6.7 0.0 0.0 0.0 1.5 70.7 3.2 1.8 18.4 1.1 0.0 0.2 0.0 0.1 0.0 0.0 315.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 3.4 0.0 0.0 2.1 0.0 0.0 0.0 7.9 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.6 0.1 0.1 0.0 0.1 5.3 3.3 0.0 0.0 0.0 1.3 0.0 11.8 0.0 1.3 0.1 1.1 0.0 14.1 0.6 1.9 0.0 10.3 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.4 8.8 5.1 4.1 5.6 13.1 7.9 12.0 5.3 4.7 6.7 0.5 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.8 0.2 0.4 2389.7 0.0 0.0 3.7 0.0 2.8 0.0 0.0 13.7 1.4 55.5 0.1 0.7 26.6 0.0 0.0 0.0 0.2 1.4 46.3 0.0 0.1 0.0 0.4 0.0 0.0 1.6 1.7 0.1 0.0 0.0 0.0 4.6 74.2 14.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.2 0.0 0.0 6.8 0.0 0.5 0.0 0.2 0.0 0.6 0.0 20.2 42.6 1.9 0.9 0.1 2.6 3.3 0.5 3.0 0.0 0.1 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 IAH1 ENSG00000134330 "Isoamyl acetate hydrolyzing esterase 1 (putative)" Q2TAA2 2 9473658-9496543 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 433.4;Late spermatids: 503.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040523, HPA076040" Approved Approved Nucleoplasm NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA040523: AB_2677021, HPA076040: " "unprognostic (1.51e-2)" "unprognostic (1.19e-2)" "unprognostic (1.27e-1)" "unprognostic (9.41e-2)" "unprognostic (9.35e-2)" "unprognostic (2.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.28e-2)" "unprognostic (2.98e-2)" "unprognostic (5.40e-2)" "unprognostic (7.39e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (2.42e-2)" "unprognostic (3.91e-2)" 40.7 47.5 27.5 16.9 28.2 27.3 34.1 32.6 37.3 33.3 32.6 41.2 20.0 30.4 31.4 26.6 28.2 23.0 56.9 27.4 29.6 39.4 46.0 31.3 27.0 27.6 27.8 35.6 23.3 45.6 31.1 24.2 28.6 26.6 29.1 22.3 22.4 29.3 43.0 22.6 26.2 27.4 27.5 25.9 29.9 65.8 29.0 28.5 28.8 72.6 31.0 30.6 29.9 31.8 41.0 40.8 4.7 0.5 73.4 140.7 0.9 33.4 76.8 48.7 46.4 0.5 44.2 21.1 17.6 106.7 35.2 27.8 15.4 32.2 48.5 81.2 26.8 26.7 16.1 27.5 139.6 0.1 21.2 85.1 92.9 36.6 42.6 93.6 49.2 37.8 0.4 13.3 100.1 39.4 106.6 4.2 6.4 53.6 20.6 26.0 0.1 6.1 79.4 21.1 29.0 56.2 26.0 37.2 52.6 2.4 37.9 46.4 38.6 38.7 17.0 17.5 52.6 10.6 0.7 8.2 53.4 16.6 44.3 33.3 38.0 31.9 30.2 35.3 33.8 38.5 35.2 34.6 49.6 32.7 27.2 30.9 23.0 37.6 42.8 52.4 46.0 25.6 27.5 28.2 32.6 37.3 27.4 29.6 27.6 27.8 28.6 27.5 29.0 31.8 44.4 32.1 26.2 25.1 53.7 89.9 100.5 92.4 21.6 33.6 41.3 51.2 45.4 52.9 40.1 49.7 12.5 74.2 65.0 36.2 92.0 68.9 433.4 49.9 56.9 30.1 25.7 41.4 43.2 76.9 109.8 73.5 16.8 50.1 36.8 74.0 36.4 53.1 87.4 42.1 35.1 28.6 42.7 78.2 95.2 503.0 93.8 66.3 92.5 19.7 116.8 44.0 80.3 23.1 44.4 90.5 37.3 73.0 38.5 75.6 68.0 138.8 42.7 57.4 98.6 82.8 75.2 243.2 48.8 41.4 95.8 44.5 64.9 87.0 47.5 89.5 IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 35000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" 55.8 49.8 19.9 33.3 21.1 18.3 41.8 23.5 25.4 35.3 37.8 54.2 43.4 31.8 31.4 47.9 41.4 30.5 60.0 20.0 21.8 65.5 83.8 31.0 38.8 22.7 22.2 39.0 33.6 80.5 16.0 40.7 25.0 36.1 54.8 34.8 40.0 37.5 92.9 40.5 40.4 39.4 21.6 28.4 39.1 30.1 22.3 31.8 39.7 85.7 43.1 35.6 30.0 22.9 137.2 125.6 70.7 69.9 104.2 104.4 169.6 81.4 86.9 87.9 70.7 121.7 138.8 125.6 107.1 101.4 68.0 129.3 99.0 101.5 100.9 87.5 119.3 62.6 94.6 137.8 64.6 100.4 64.9 76.0 101.3 95.4 97.6 84.7 86.9 79.9 156.9 70.7 116.7 75.9 79.8 72.0 92.1 106.2 82.1 69.5 140.7 202.2 126.2 90.4 38.0 106.6 123.2 188.2 130.3 80.6 218.5 111.9 89.8 86.1 71.6 117.0 138.4 60.0 98.9 90.8 91.3 77.3 97.6 33.8 24.6 22.8 23.0 27.7 30.8 23.6 24.9 30.3 29.2 18.3 27.8 25.6 4.7 28.3 22.3 10.6 29.9 26.7 19.9 21.1 23.5 25.4 20.0 21.8 22.7 22.2 25.0 21.6 22.3 22.9 66.4 35.3 38.0 15.7 30.7 20.1 28.6 44.1 34.7 28.6 40.1 39.4 144.3 22.8 42.9 29.5 25.0 79.0 31.5 54.2 11.7 47.7 20.0 63.8 48.3 43.7 36.2 29.6 17.3 65.4 55.5 37.0 32.1 44.3 19.6 41.3 37.5 99.6 45.9 20.2 22.7 55.4 28.5 51.0 11.2 6.8 37.3 35.9 19.6 15.0 46.1 34.6 27.8 16.6 31.5 67.4 44.9 42.5 33.1 34.1 38.4 36.1 62.0 35.5 46.0 46.3 39.0 44.6 44.1 63.5 26.6 71.7 31.0 54.4 69.9 27.6 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 ID1 "bHLHb24, dJ857M17.1.2" ENSG00000125968 "Inhibitor of DNA binding 1, HLH protein" P41134 20 31605283-31606515 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1667.3;Basal respiratory cells: 1443.4;Hepatic stellate cells: 2131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 509.6;HaCaT: 500.2;Hep G2: 425.3;PC-3: 515.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025915, HPA051456, HPA058518" Approved Enhanced Nucleoplasm "Intracellular and membrane" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB025915: , HPA051456: AB_2681492, HPA058518: AB_2683740" "unprognostic (3.89e-2)" "unprognostic (3.45e-2)" "unprognostic (2.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.85e-4)" "unprognostic (2.29e-1)" "unprognostic (1.58e-1)" "unprognostic (2.14e-2)" "unprognostic (7.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.71e-3)" "unprognostic (2.97e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-3)" 242.2 88.5 53.0 20.2 43.1 9.0 141.3 50.1 57.1 125.7 60.9 136.7 78.4 116.0 4.7 340.4 146.3 35.0 291.9 45.3 56.8 218.1 154.1 204.7 14.0 69.3 56.0 66.8 42.4 8.1 167.8 45.7 62.3 202.5 26.4 5.1 58.5 149.6 53.8 129.6 154.3 12.2 53.3 79.7 162.5 16.4 79.1 5.9 266.8 37.8 6.2 351.1 206.9 47.1 76.1 245.3 2.7 49.3 31.2 14.1 187.6 314.1 12.6 56.9 6.2 130.5 111.4 0.6 509.6 84.3 67.2 500.2 40.1 17.9 8.6 6.2 25.6 41.5 229.2 425.3 42.3 0.9 2.2 57.4 69.7 0.3 4.3 93.5 35.0 27.6 94.0 2.3 110.4 99.8 11.4 1.8 172.7 336.5 515.3 0.9 200.8 4.2 11.1 206.1 93.5 87.4 261.3 91.9 2.4 128.8 57.0 7.6 188.5 151.3 300.0 49.0 216.1 5.6 6.3 5.2 176.2 39.5 21.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 0.2 0.0 0.0 0.1 53.0 43.1 50.1 57.1 45.3 56.8 69.3 56.0 62.3 53.3 79.1 47.1 1667.3 237.2 171.7 88.2 25.1 102.3 992.2 1443.4 406.3 2.7 98.6 114.3 35.1 112.9 685.1 228.1 4.2 129.9 46.3 594.3 37.2 584.1 5.7 794.1 450.1 907.7 572.7 49.9 0.6 535.5 493.7 195.3 675.3 707.6 22.2 8.9 2131.4 109.1 25.6 0.0 0.5 557.4 321.4 72.2 52.4 8.7 28.6 38.9 90.7 92.8 8.2 85.0 1.0 4.0 0.3 257.4 924.9 0.4 26.7 519.7 579.8 7.1 168.1 8.3 13.1 229.7 206.1 3.2 53.7 455.8 87.9 89.1 39.8 15.9 389.1 591.6 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 IFFO1 "HOM-TES-103, IFFO" ENSG00000010295 "Intermediate filament family orphan 1" Q0D2I5 12 6538961-6556073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069344 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA069344: AB_2686126" "unprognostic (1.05e-1)" "unprognostic (4.19e-2)" "unprognostic (4.38e-2)" "unprognostic (3.33e-3)" "unprognostic (2.69e-2)" "unprognostic (1.43e-3)" "unprognostic (4.37e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (5.25e-2)" "prognostic favorable (6.53e-5)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.47e-7)" "unprognostic (5.71e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (5.58e-2)" 9.4 7.7 5.4 5.7 5.8 6.3 6.0 6.1 11.5 10.8 3.0 9.1 3.0 10.3 1.5 2.5 8.2 4.4 8.2 6.1 6.3 4.7 5.6 8.0 7.3 6.9 5.1 7.9 3.2 0.6 7.4 4.9 7.2 5.6 2.5 3.6 3.0 5.0 10.6 3.4 6.2 5.3 4.7 11.5 3.7 7.2 6.5 5.0 4.0 4.6 4.8 8.8 6.8 7.6 0.1 0.0 6.1 0.0 9.1 15.0 0.0 9.2 8.3 7.3 6.4 1.2 0.1 1.7 0.0 8.9 2.3 0.0 4.6 1.3 2.4 13.8 15.2 7.2 0.2 10.2 6.3 7.3 11.5 9.2 0.0 5.5 0.0 8.6 7.2 7.7 0.0 2.0 18.2 0.0 6.5 5.8 14.1 0.0 0.0 9.7 10.6 3.3 2.4 0.0 0.0 5.5 0.0 0.0 4.6 6.2 0.0 7.1 11.1 7.0 0.0 5.7 5.2 3.0 0.8 5.6 5.2 3.1 18.7 0.1 4.8 2.8 1.6 3.3 1.5 0.8 1.4 1.7 3.1 0.9 0.5 0.9 1.3 2.7 6.6 1.6 1.1 2.4 5.4 5.8 6.1 11.5 6.1 6.3 6.9 5.1 7.2 4.7 6.5 7.6 14.9 0.0 2.4 16.0 8.9 2.5 0.3 0.7 0.0 15.0 1.3 2.7 10.9 1.5 0.7 0.0 4.2 4.4 17.7 0.6 1.9 0.7 13.2 0.5 9.2 12.6 0.0 3.8 28.9 1.4 3.1 14.1 1.5 0.6 1.3 11.6 11.7 6.5 21.6 21.9 20.5 1.4 0.0 23.1 9.1 11.2 19.0 17.4 19.6 15.9 12.7 11.1 16.5 13.0 10.5 0.4 1.4 13.5 12.0 0.3 1.2 2.8 0.2 12.7 32.9 15.8 13.2 5.6 5.0 0.6 2.0 1.2 12.9 10.1 1.1 0.2 IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116698 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3792.9;Distal enterocytes: 2150.5;Endothelial cells: 1972.1;Exocrine glandular cells: 1603.8;Intestinal goblet cells: 1638.8;Pancreatic endocrine cells: 1678.1;Paneth cells: 2179.2;Proximal enterocytes: 3048.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;T-cells: 2.6" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 2026.8;BJ hTERT+ SV40 Large T+ RasG12V: 1782.5;EFO-21: 547.7;Karpas-707: 501.5;SK-MEL-30: 607.2" HPA028875 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" 470.3 323.3 178.3 115.7 177.4 162.8 410.3 180.9 232.6 351.4 162.7 374.4 129.2 137.8 39.9 310.4 163.2 344.1 471.5 174.5 182.4 217.9 150.4 608.2 48.3 203.8 187.7 75.6 39.3 30.3 65.3 183.8 215.0 85.0 221.4 6.1 156.9 47.0 113.1 129.8 256.2 117.4 194.9 797.8 697.0 140.2 194.1 202.8 149.8 152.4 54.2 116.9 213.7 190.8 181.3 0.4 1.3 0.4 0.5 21.7 1.7 2.8 8.8 2026.8 1782.5 3.8 146.8 1.5 547.7 115.3 33.8 5.7 1.1 0.2 79.7 2.1 3.7 1.0 1.4 0.9 13.7 0.6 1.1 2.0 2.0 353.8 0.1 1.1 284.0 1.3 1.1 501.5 0.1 0.5 1.7 1.1 0.5 0.5 24.7 1.8 0.5 0.6 1.2 0.6 0.4 1.1 0.0 0.1 607.2 1.4 0.9 3.0 0.3 0.2 2.7 325.8 1.0 9.4 14.6 3.9 0.9 0.5 1.4 0.0 1.3 0.5 0.3 7.0 0.3 0.0 2.6 0.7 0.8 0.1 0.0 0.4 0.0 0.4 2.1 0.1 2.5 2.1 178.3 177.4 180.9 232.6 174.5 182.4 203.8 187.7 215.0 194.9 194.1 190.8 3792.9 391.0 82.7 1.3 26.8 171.2 6.5 126.9 91.6 4.9 23.4 38.2 45.9 151.5 237.4 12.9 8.4 7.3 14.9 2150.5 1.9 50.6 13.6 1035.5 188.3 1972.1 267.8 42.3 0.6 1603.8 221.2 330.8 892.5 838.5 45.1 1174.4 742.5 5.8 158.3 5.0 0.4 1638.8 107.8 106.9 163.5 36.7 172.1 59.6 350.4 84.3 26.1 8.3 0.0 0.0 0.7 1678.1 2179.2 417.5 6.3 11.1 3048.1 23.7 548.1 20.5 276.1 45.2 295.8 20.3 12.1 151.9 140.4 5.2 34.1 302.4 523.4 80.4 IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 155.9;Kupffer cells: 205.4;Langerhans cells: 139.3;Macrophages: 426.2;monocytes: 144.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Cell line enhanced" "Detected in many" "Daudi: 655.7;RPMI-8226: 717.7;SK-BR-3: 457.4;U-266/84: 794.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" 132.4 121.0 18.4 708.3 20.8 283.8 58.6 20.3 104.5 40.8 48.7 129.0 197.3 22.2 26.9 38.7 57.3 109.6 31.2 18.0 23.3 80.3 148.2 572.7 370.7 32.0 24.9 14.8 61.3 75.0 27.9 128.8 40.5 31.6 148.0 2.6 66.3 22.0 12.6 55.0 153.6 165.0 26.8 385.3 112.2 16.0 69.4 91.9 54.2 9.0 221.0 215.7 19.6 49.8 115.5 59.2 0.4 37.9 11.2 19.9 102.6 11.8 17.2 34.6 91.8 132.3 193.1 655.7 96.6 39.7 175.2 85.1 69.9 30.1 3.7 182.5 55.2 8.1 98.1 188.9 111.8 20.1 46.9 70.4 60.4 59.8 19.7 4.4 2.0 23.8 96.8 394.8 16.6 217.3 9.9 2.5 21.2 380.6 68.7 65.8 4.5 717.7 101.1 3.7 5.3 8.0 200.5 457.4 11.3 7.4 31.6 8.8 4.2 55.2 34.2 120.7 12.0 14.6 794.7 368.5 154.1 133.5 8.5 106.9 9509.8 3890.4 40.8 14243.6 38.8 952.6 28.5 31.1 5699.9 708.1 19.7 24.3 2102.8 70.2 9865.9 173.2 41.5 11082.7 18.4 20.8 20.3 104.5 18.0 23.3 32.0 24.9 40.5 26.8 69.4 49.8 6.4 9.6 38.8 0.0 54.2 3.6 2.5 2.1 2.2 0.4 8.6 13.2 1.1 4.3 18.3 12.9 0.0 5.6 4.0 8.3 1.9 1.8 0.3 2.5 1.7 8.4 0.0 4.6 0.1 1.1 14.8 8.1 6.6 4.1 13.9 0.2 3.6 1.3 155.9 0.0 0.1 14.9 2.0 205.4 139.3 0.2 0.3 426.2 5.4 1.0 144.1 0.7 5.2 0.0 0.1 1.2 3.4 0.0 47.7 4.6 5.9 5.4 8.9 0.7 0.0 2.6 1.8 0.2 0.7 3.7 3.3 12.0 9.6 1.5 9.6 1.2 IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159740 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.5;lymphoid tissue: 7.4" "Group enriched" "Detected in many" 12 "dendritic cells: 283.2;T-cells: 200.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "gdT-cell: 5.5;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.6;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010344 Approved "Secreted to blood" NA NA 1470 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 7: Non-specific - Mitochondria" "CAB010344: AB_2123447" "unprognostic (2.16e-4)" "unprognostic (1.93e-3)" "unprognostic (9.21e-2)" "unprognostic (1.04e-4)" "unprognostic (5.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.33e-1)" "unprognostic (3.17e-4)" "unprognostic (7.79e-2)" "unprognostic (7.97e-3)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (7.62e-9)" "unprognostic (3.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.32e-2)" "unprognostic (7.38e-3)" 0.7 0.7 0.1 3.5 0.2 11.5 0.3 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.0 0.0 0.3 1.5 1.8 7.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.9 0.2 0.0 0.0 0.3 0.2 0.0 1.3 0.4 0.1 0.1 0.5 0.3 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.4 6.6 0.0 0.4 0.5 3.7 0.1 0.9 0.0 0.0 0.1 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.0 0.0 0.0 3.1 3.2 1.3 0.0 0.0 0.0 4.8 5.5 0.2 1.5 0.0 0.0 0.0 0.0 283.2 0.1 0.0 0.0 0.2 1.0 1.1 1.3 0.0 0.4 0.0 0.0 0.0 1.5 6.1 1.1 0.0 0.0 1.4 1.2 0.1 0.0 0.0 0.5 0.0 4.4 5.5 0.0 0.0 10.4 7.2 0.0 0.0 0.0 19.6 0.0 0.1 0.0 1.1 0.0 10.9 0.2 0.0 0.3 0.0 0.0 0.0 1.0 2.9 0.0 0.0 0.8 4.0 0.0 200.1 0.0 0.2 0.2 IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 86.7;cervix: 89.0" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 1279.3;Leydig cells: 1103.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Cell line enhanced" "Detected in some" "ASC diff: 37.9;HDLM-2: 49.6;K-562: 22.4;Karpas-707: 11.3;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048946 Approved "Secreted to blood" NA NA 103000000 330000000 "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" 86.7 5.1 1.2 27.1 1.8 0.9 38.7 0.3 2.3 89.0 1.3 6.9 5.4 46.9 10.6 6.6 13.0 21.5 15.1 2.2 1.0 3.1 83.5 11.6 6.5 2.5 1.1 9.0 3.9 1.4 1.2 24.2 2.0 38.5 6.7 5.4 7.6 33.4 8.5 4.9 5.7 74.3 1.2 9.8 7.7 7.6 2.0 3.1 25.4 5.9 3.7 21.3 22.7 0.9 0.3 0.0 0.0 0.0 37.9 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 22.4 11.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.2 0.2 1.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.4 1.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.8 0.3 2.3 2.2 1.0 2.5 1.1 2.0 1.2 2.0 0.9 11.8 3.2 2.2 1.0 8.5 2.5 0.7 0.0 1.8 168.1 4.0 6.2 0.4 2.8 0.7 0.0 0.0 1.1 0.6 0.2 0.0 0.0 17.5 35.8 1279.3 38.9 0.0 5.3 1.2 0.6 1.5 259.7 2.6 34.5 0.0 0.3 6.4 243.0 122.0 0.0 123.9 0.0 16.2 25.8 12.5 58.0 1103.2 42.0 14.2 27.2 3.6 4.4 0.0 0.5 0.9 0.1 0.0 193.4 66.9 1.2 0.0 1.4 0.1 9.0 0.0 139.3 19.6 1.9 1.2 1.6 2.7 1.2 9.1 69.4 0.2 0.4 IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1198.4" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 994.8" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Hep G2: 54.7;U-2197: 84.9;U-87 MG: 145.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 28100000 25000000 "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" 2.6 0.1 0.2 0.0 0.2 0.0 2.4 0.2 0.3 0.3 0.1 0.0 0.3 79.6 0.1 0.0 4.1 0.3 0.5 0.2 0.3 1.6 1198.4 0.1 0.1 0.8 0.3 46.3 0.5 0.0 0.5 204.5 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.3 1.1 0.3 0.0 0.0 0.0 0.2 0.2 0.2 6.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.6 0.3 1.4 0.1 1.6 0.3 0.0 0.0 0.7 0.0 0.0 0.3 0.5 54.7 0.3 1.1 0.1 0.1 0.7 11.3 0.1 0.6 0.3 0.0 0.2 0.1 1.3 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.3 0.0 2.2 0.0 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 84.9 0.0 0.0 0.0 0.2 145.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.3 0.8 0.3 0.9 0.2 0.3 0.2 0.4 0.0 0.5 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 5.7 1.0 35.8 0.7 0.0 0.0 0.9 0.0 0.0 0.0 11.0 0.1 4.7 94.3 0.9 3.5 10.7 0.1 0.0 1.6 1.8 0.0 15.9 0.0 2.1 6.8 994.8 1.7 0.0 0.1 0.0 0.0 14.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.1 0.5 0.0 0.0 3.4 0.8 0.0 0.0 0.0 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 580.8;Fibroblasts: 1360.5;Leydig cells: 1030.8;Peritubular cells: 1495.9;Sertoli cells: 1170.1;Smooth muscle cells: 420.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 1163.6;BJ: 476.9;BJ hTERT+: 683.3;fHDF/TERT166: 1045.9;hTERT-RPE1: 468.5;U-87 MG: 631.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 145.8 90.2 28.1 9.2 32.6 0.4 150.5 31.8 40.8 276.6 71.6 75.5 20.8 117.2 129.5 75.8 237.4 36.8 107.0 28.4 33.1 30.6 7.7 40.4 8.7 32.7 29.2 136.8 15.9 4.8 106.3 15.7 33.2 129.3 28.0 6.6 35.9 122.2 38.5 39.2 52.5 39.0 36.7 45.2 67.6 22.2 41.7 6.8 58.4 102.2 9.2 127.1 214.1 27.2 135.3 219.6 0.2 177.3 313.9 1163.6 0.8 476.9 683.3 126.9 69.0 23.2 294.7 0.0 68.5 1045.9 96.4 453.3 3.0 42.3 26.2 1.2 2.8 4.4 37.1 33.3 111.9 0.8 1.1 325.5 2.3 57.4 11.9 468.5 30.5 7.5 0.6 9.3 53.1 0.5 6.6 1.0 6.8 4.1 150.4 2.3 4.9 5.6 10.1 3.3 1.3 8.7 152.2 0.0 10.9 4.0 6.3 0.5 132.2 87.2 41.2 95.5 18.0 5.3 10.7 0.6 631.6 6.7 49.5 0.0 0.0 31.6 0.6 6.8 3.4 0.1 1.0 5.4 2.1 0.0 0.5 6.8 0.0 0.0 20.1 0.0 0.0 1.5 28.1 32.6 31.8 40.8 28.4 33.1 32.7 29.2 33.2 36.7 41.7 27.2 83.9 6.4 4.2 2.0 3.4 113.6 41.0 580.8 23.9 2.5 5.9 29.0 21.1 10.0 37.6 20.2 0.0 3.0 3.5 0.2 11.7 87.9 9.6 4.9 99.2 71.9 0.0 3.2 3.1 8.0 4.9 1360.5 30.5 2.5 0.0 2.3 116.4 0.8 7.6 0.0 3.6 0.3 50.8 6.8 122.8 32.6 1030.8 15.2 144.1 19.7 2.5 51.1 0.0 1.5 0.9 77.1 0.0 1495.9 9.6 94.9 0.0 15.2 13.9 2.8 1170.1 102.3 420.9 3.8 6.8 8.0 87.8 3.4 14.1 0.4 0.0 34.1 IGHA1 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 7411.2;lymphoid tissue: 6397.6;salivary gland: 8904.9;stomach 1: 6664.9" "Group enriched" "Detected in many" 10 "B-cells: 17763.5;Plasma cells: 34095.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2571.8;naive B-cell: 1114.6" "Lineage enriched" "Detected in many" 284 "B-cells: 2571.8" "Cell line enhanced" "Detected in many" "HDLM-2: 17.4;RPMI-8226: 34.7;SH-SY5Y: 22.3;U-266/70: 78.2;U-266/84: 24.0" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 130000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" 200.6 41.7 1.4 1121.1 1.0 918.5 953.5 0.7 6.5 214.3 4.2 5973.6 7411.2 79.9 3.5 641.9 203.5 662.9 73.8 0.6 1.3 278.5 327.7 1305.3 1420.6 3.5 1.1 40.6 115.1 3.5 38.3 6.7 1.1 202.5 1338.5 0.0 8904.9 69.0 10.8 56.7 3788.8 69.5 1.4 6397.6 6664.9 23.2 1.0 131.0 447.3 0.4 1949.0 1616.2 302.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.8 0.0 0.0 3.6 0.0 0.0 0.0 17.4 0.0 3.7 0.0 0.0 0.0 5.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 4.1 14.4 5.5 0.0 0.0 3.8 4.3 34.7 0.0 0.0 9.7 22.3 2.6 0.0 0.0 0.0 0.0 1.6 5.1 0.0 3.9 4.2 3.2 78.2 24.0 2.2 0.0 2.4 0.0 3.8 3.0 0.6 1.3 0.3 1.0 2571.8 0.7 1.1 1.5 1114.6 0.4 1.0 9.0 0.9 0.9 1.7 1.0 508.3 1.4 1.0 0.7 6.5 0.6 1.3 3.5 1.1 1.1 1.4 1.0 1.9 11.8 131.4 783.5 0.0 17763.5 0.0 26.0 0.0 1.2 0.0 22.4 4.6 4.7 22.8 46.4 0.0 0.0 0.7 55.5 20.8 0.0 0.0 0.0 0.1 0.1 26.5 28.4 167.0 0.0 0.0 0.5 56.5 99.4 0.1 584.8 0.0 353.8 225.1 1.6 0.0 0.0 13.6 0.0 57.8 0.0 0.0 0.0 34.6 0.0 0.0 6.7 0.0 11.3 0.0 0.0 0.0 12.8 0.0 34095.8 33.2 0.0 1.4 16.0 0.0 0.0 2.0 13.6 0.0 0.0 0.8 0.0 6.0 2514.2 0.0 27.9 1.2 IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5017.7;salivary gland: 3728.4" "Group enriched" "Detected in many" 22 "B-cells: 3713.4;Plasma cells: 10918.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 876 "memory B-cell: 279.6;naive B-cell: 123.8" "Lineage enriched" "Detected in single" 1214 "B-cells: 279.6" "Group enriched" "Detected in some" 42 "U-266/70: 181.9;U-266/84: 63.9" "Not detected" "Not detected" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 67000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" 24.3 3.7 0.0 14.2 0.0 12.4 329.7 0.0 0.0 47.6 0.0 5017.7 15.3 8.9 0.0 219.7 35.0 0.9 4.8 0.0 0.0 49.7 35.1 134.2 6.8 0.0 0.0 5.3 30.3 0.0 4.9 0.3 0.0 37.7 8.8 0.0 3728.4 0.1 2.1 17.8 2261.3 1.0 0.0 700.9 670.1 1.1 0.0 22.4 59.8 0.0 13.0 93.4 67.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.9 181.9 63.9 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 279.6 0.0 0.1 0.1 123.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 12.4 0.0 3713.4 0.0 2.4 0.0 2.8 0.0 1.4 0.3 1.2 5.7 0.6 0.0 0.0 0.1 3.2 3.7 0.0 0.0 0.0 0.0 0.0 15.6 8.5 56.2 0.0 0.0 0.0 8.0 10.7 0.0 15.2 0.0 78.9 6.0 0.3 0.0 0.0 2.9 0.0 10.8 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 10918.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 12.3 0.0 0.4 325.4 0.0 4.8 0.2 IGHD "FLJ00382, FLJ46727, MGC29633" ENSG00000211898 "Immunoglobulin heavy constant delta" P01880 14 105836765-105845678 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 330.9" "Group enriched" "Detected in some" 47 "B-cells: 261.8;Plasma cells: 588.1;T-cells: 474.2" "Cancer enhanced" "Detected in many" "lung cancer: 58.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 63 "memory B-cell: 279.1;naive B-cell: 815.9" "Lineage enriched" "Detected in many" 93 "B-cells: 815.9" "Group enriched" "Detected in some" 7 "Daudi: 82.3;U-698: 95.8" CAB012703 Approved "Immunoglobulin genes" NA NA 14000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB012703: AB_10554307" "prognostic favorable (1.49e-6)" "unprognostic (1.84e-2)" "unprognostic (3.99e-2)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (2.08e-3)" "unprognostic (4.63e-2)" "unprognostic (3.28e-1)" "unprognostic (8.18e-2)" "unprognostic (6.16e-2)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-3)" "unprognostic (5.76e-2)" "unprognostic (2.64e-1)" "unprognostic (3.82e-3)" "unprognostic (4.30e-2)" 2.8 0.4 0.0 35.4 0.0 39.2 9.3 0.0 0.4 0.9 0.0 2.2 3.4 5.0 0.2 2.8 0.6 19.0 5.7 0.0 0.0 2.1 3.5 34.1 111.6 0.2 0.0 0.3 0.4 0.2 0.0 0.3 0.0 6.4 1.9 0.0 67.1 1.2 0.4 1.5 17.6 0.9 0.0 146.7 43.3 0.3 0.1 8.3 1.3 0.0 330.9 20.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 82.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 12.4 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 2.7 0.5 0.3 0.4 0.3 0.2 279.1 0.3 0.8 0.7 815.9 1.0 0.3 3.3 0.3 0.5 8.7 0.4 39.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 261.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.3 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.7 0.0 9.2 0.0 0.0 0.0 0.0 0.0 588.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 474.2 0.0 0.0 0.0 IGHD2-15 "D2, IGHD215" ENSG00000211918 "Immunoglobulin heavy diversity 2-15" 14 105897957-105897987 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "bone marrow: 2.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "endometrial cancer: 3.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "naive B-cell: 39.9" "Lineage enriched" "Detected in single" 400 "B-cells: 39.9" "Cell line enriched" "Detected in single" 28 "HEL: 2.7" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD2-2 IGHD22 ENSG00000211931 "Immunoglobulin heavy diversity 2-2" 14 105916826-105916856 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 14 "bone marrow: 2.9;intestine: 2.5;lymphoid tissue: 2.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 3.0" "Lineage enriched" "Detected in single" 31 "B-cells: 3.0" "Cell line enriched" "Detected in single" 23 "NB-4: 2.3" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "unprognostic (3.23e-3)" "unprognostic (1.40e-1)" 0.0 0.0 0.0 0.9 0.0 2.9 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD2-21 IGHD221 ENSG00000211912 "Immunoglobulin heavy diversity 2-21" 14 105888551-105888578 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD3-10 "DXP'1, IGHD310" ENSG00000211923 "Immunoglobulin heavy diversity 3-10" 14 105904497-105904527 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "bone marrow: 1.3;intestine: 3.7;lymphoid tissue: 4.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "naive B-cell: 5.4" "Lineage enriched" "Detected in single" 55 "B-cells: 5.4" "Cell line enriched" "Detected in single" 12 "NB-4: 1.1" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" 0.0 0.0 0.0 1.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 4.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD3-16 IGHD316 ENSG00000211917 "Immunoglobulin heavy diversity 3-16" 14 105895634-105895670 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "bone marrow: 4.0;intestine: 2.6;lymphoid tissue: 4.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 27.0" "Lineage enriched" "Detected in many" 12 "B-cells: 27.0" "Group enriched" "Detected in some" 16 "HEL: 2.4;HMC-1: 1.3;NB-4: 1.0" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" 0.0 0.0 0.0 1.7 0.0 4.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.8 0.0 0.0 0.0 2.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 27.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD3-22 IGHD322 ENSG00000211911 "Immunoglobulin heavy diversity 3-22" 14 105886031-105886061 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.6;lymphoid tissue: 2.7;stomach 1: 3.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 48.9" "Lineage enriched" "Detected in many" 7 "B-cells: 48.9" "Cell line enriched" "Detected in single" 13 "SH-SY5Y: 1.3" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "unprognostic (4.12e-1)" "unprognostic (1.53e-1)" 0.0 0.0 0.1 0.9 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.2 3.1 0.0 0.0 0.7 0.0 0.0 2.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 48.9 0.0 0.0 6.9 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD3-3 "DXP4, IGHD33" ENSG00000211930 "Immunoglobulin heavy diversity 3-3" 14 105914359-105914389 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 4.3;lymphoid tissue: 2.6;salivary gland: 3.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 62.6" "Lineage enriched" "Detected in single" 626 "B-cells: 62.6" "Group enriched" "Detected in some" 48 "NB-4: 6.9;SH-SY5Y: 2.6" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-1)" "unprognostic (1.75e-1)" 0.0 0.0 0.0 0.9 0.1 4.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.0 0.0 0.0 1.0 0.0 0.0 1.9 1.6 0.1 0.0 0.1 0.0 0.0 0.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD3-9 "DXP1, IGHD39" ENSG00000211924 "Immunoglobulin heavy diversity 3-9" 14 105904681-105904711 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.9;stomach 1: 4.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 214 "memory B-cell: 8.9;naive B-cell: 33.8" "Lineage enriched" "Detected in single" 339 "B-cells: 33.8" "Cell line enriched" "Detected in some" 5 "HEL: 5.5" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "unprognostic (1.74e-1)" "unprognostic (1.50e-1)" "unprognostic (9.31e-2)" 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 2.1 1.6 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 0.4 0.0 0.0 2.0 0.0 0.1 2.8 4.8 0.0 0.1 2.2 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD4-17 IGHD417 ENSG00000227800 "Immunoglobulin heavy diversity 4-17" 14 105894508-105894523 "Immunoglobulin genes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 16 "B-cells: 3900.5;Plasma cells: 9883.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Group enriched" "Detected in many" 9 "Karpas-707: 157.8;U-698: 392.7" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" 526.0 696.8 0.7 1661.1 0.6 681.1 203.2 0.5 4.5 518.2 2.8 302.1 103.7 210.6 18.4 334.4 661.5 312.9 143.2 0.4 2.2 491.7 356.1 962.4 3281.1 4.7 3.2 407.0 38.5 7.9 35.8 2.3 2.3 209.8 85.1 0.3 391.6 250.8 13.1 28.5 1008.8 27.6 12.7 11451.9 608.9 172.8 1.2 1773.7 1277.9 0.1 5826.8 3998.0 267.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.7 0.0 0.0 2.3 0.0 0.0 0.0 8.4 0.0 5.3 0.0 0.0 0.0 22.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 157.8 0.0 0.0 1.7 2.1 2.6 0.0 0.0 2.9 15.1 3.7 0.0 0.0 18.2 17.0 3.1 0.0 0.0 0.0 0.0 0.2 10.8 0.0 3.2 3.3 4.5 4.9 0.3 392.7 0.1 3.7 0.0 0.2 0.3 0.1 0.3 0.0 0.2 766.8 0.6 0.3 0.4 134.9 0.0 0.1 6.2 0.1 0.1 0.1 0.2 96.2 0.7 0.6 0.5 4.5 0.4 2.2 4.7 3.2 2.3 12.7 1.2 1.8 2.9 73.7 378.5 0.0 3900.5 0.0 8.1 0.0 0.0 0.0 0.5 0.0 2.8 22.8 9.3 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.5 0.0 0.1 8.5 13.9 83.4 0.0 0.0 0.0 13.6 8.2 0.0 209.4 0.0 46.1 52.9 0.1 0.0 0.0 5.0 0.0 62.8 0.0 0.9 0.0 9.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 5.4 0.0 9883.3 9.1 0.0 10.9 1.5 0.1 0.0 0.0 1.5 1.9 1.0 0.0 0.0 0.0 415.6 0.0 13.6 0.1 IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4319.4" "Group enriched" "Detected in some" 8 "B-cells: 2050.1;Plasma cells: 2918.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 447 "memory B-cell: 339.0;naive B-cell: 119.3" "Lineage enriched" "Detected in single" 661 "B-cells: 339.0" "Group enriched" "Detected in some" 4 "RH-30: 9.6;RPMI-8226: 25.1" HPA001245 Approved "Immunoglobulin genes" NA NA 250000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" 109.5 11.0 1.3 170.0 1.4 34.8 56.0 0.2 4.1 59.9 0.8 202.8 7.5 55.8 0.8 90.2 51.5 20.7 15.2 0.2 1.1 157.5 98.2 171.0 65.4 0.9 0.2 16.3 8.0 0.1 8.2 0.0 0.5 64.2 9.4 0.0 201.2 1.2 3.5 13.3 330.7 1.0 1.5 4319.4 87.2 2.3 0.3 16.7 134.4 0.0 226.0 100.4 104.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 25.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 339.0 0.5 0.0 0.3 119.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 34.5 1.3 1.4 0.2 4.1 0.2 1.1 0.9 0.2 0.5 1.5 0.3 1.8 0.2 54.5 305.3 0.0 2050.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 2.8 13.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 4.1 0.0 32.5 0.0 0.0 0.0 3.1 0.0 0.0 126.1 0.0 8.2 5.1 0.1 0.0 0.0 0.9 0.0 12.4 0.0 0.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2918.6 0.7 0.0 3.5 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.1 305.5 0.0 0.7 0.0 IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 7 "B-cells: 2548.4;Plasma cells: 4543.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 5 "HDLM-2: 23.8;Karpas-707: 18.7;U-698: 49.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" 63.6 17.6 0.1 90.8 0.3 65.4 23.8 0.1 1.5 37.9 1.0 30.0 11.6 22.8 0.3 32.2 104.4 8.4 6.7 0.1 0.6 72.8 42.4 194.9 346.3 2.8 0.1 13.4 6.3 0.1 6.8 0.1 0.4 41.4 8.8 0.0 69.9 12.7 1.9 2.3 100.9 1.6 1.2 1289.1 65.4 31.7 0.1 27.1 87.6 0.0 929.0 87.3 29.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 6.0 3.9 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 49.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 211.0 0.0 0.0 0.0 64.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.7 0.1 0.3 0.1 1.5 0.1 0.6 2.8 0.1 0.4 1.2 0.1 1.0 1.9 57.7 363.7 0.0 2548.4 0.0 9.7 0.0 0.0 0.0 0.5 0.1 1.9 18.6 11.2 0.0 0.0 0.0 2.0 7.0 0.0 0.0 6.5 0.1 0.2 5.3 13.2 24.5 0.0 0.0 0.0 9.1 2.6 0.0 195.5 0.0 22.9 64.2 0.1 0.0 0.0 7.4 0.0 62.8 0.0 16.4 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 4543.8 13.3 0.0 0.5 2.2 0.0 0.0 0.0 0.7 4.7 0.7 0.0 0.0 0.0 467.3 0.0 13.5 0.1 IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Group enriched" "Detected in some" 10 "B-cells: 964.5;Plasma cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 339.7" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" 80.0 2.1 0.4 2478.2 0.6 42.2 5.8 0.5 1.0 33.9 0.3 40.6 85.5 10.8 0.2 401.2 28.5 101.3 19.2 0.3 0.4 44.0 43.7 49.4 136.5 0.6 0.4 3.9 4.2 0.5 1.9 0.2 1.3 31.2 44.3 0.1 16.4 4.1 0.8 4.7 186.2 1.8 1.1 831.6 57.4 2.2 0.4 49.9 108.3 0.0 872.5 588.7 29.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 43.2 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.3 0.6 339.7 0.0 0.0 3.5 3.7 0.3 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.9 0.3 1.5 0.6 0.1 57.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 122.7 0.0 0.0 0.1 73.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.6 0.4 0.6 0.5 1.0 0.3 0.4 0.6 0.4 1.3 1.1 0.4 0.3 1.3 6.4 118.8 0.0 964.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.0 8.6 3.7 0.0 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.0 0.4 2.5 27.8 26.7 0.0 0.0 0.0 4.3 0.0 0.0 50.4 0.0 16.4 36.7 0.0 0.0 0.0 10.5 0.0 51.9 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.3 0.0 2099.3 0.2 0.0 10.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 152.3 0.0 12.8 0.1 IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 18 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.7;U-698: 1.8" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" 8.6 5.3 0.1 196.9 0.1 35.6 72.8 0.0 1.9 18.6 0.2 260.2 354.8 3.3 0.0 15.7 5.2 12.6 1.4 0.1 0.1 2.3 6.1 28.5 46.8 1.3 0.0 8.2 3.1 0.4 0.0 0.7 0.5 4.3 182.6 0.0 120.1 0.5 0.0 0.0 171.1 12.0 0.3 100.2 305.5 1.0 0.2 14.6 2.9 0.0 414.0 61.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.2 276.3 0.6 2.5 0.2 180.8 0.3 0.3 0.0 0.1 0.1 99.0 0.2 29.1 0.1 0.1 0.0 1.9 0.1 0.1 1.3 0.0 0.5 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ2 ENSG00000211904 "Immunoglobulin heavy joining 2" 14 105865199-105865250 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "cervix: 48.7;intestine: 127.5;lymphoid tissue: 174.5" "Cell type enriched" "Detected in single" 6 "Plasma cells: 3.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "medulla oblongata: 3.8" "Group enriched" "Detected in some" 18 "MAIT T-cell: 49.0;naive B-cell: 12.6" "Group enriched" "Detected in many" 45 "B-cells: 12.6;T-cells: 49.0" "Group enriched" "Detected in some" 25 "Daudi: 3.8;K-562: 1.1" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (1.27e-2)" "prognostic favorable (1.05e-4)" "unprognostic (7.40e-2)" "unprognostic (6.38e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.33e-6)" "unprognostic (4.31e-2)" "unprognostic (1.68e-1)" "unprognostic (5.48e-2)" "unprognostic (4.60e-1)" 2.0 0.0 0.2 0.0 0.5 13.3 20.5 0.2 2.0 48.7 0.1 87.2 0.0 5.4 17.9 18.0 2.1 0.8 0.1 0.2 0.4 1.2 12.0 0.0 7.6 3.8 0.8 7.7 18.9 0.6 0.0 0.0 0.5 15.0 127.5 0.0 0.0 7.1 0.0 0.0 0.0 5.8 0.6 18.8 18.2 0.1 0.5 19.6 5.1 0.0 174.5 6.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 49.0 1.3 0.4 1.6 0.4 12.6 0.0 0.2 0.2 0.0 0.6 0.0 0.0 17.1 0.2 0.5 0.2 2.0 0.2 0.4 3.8 0.8 0.5 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHJ4 ENSG00000240041 "Immunoglobulin heavy joining 4" 14 105864215-105864260 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 416.7;lymphoid tissue: 1568.0;urinary bladder: 551.2" "Cell type enriched" "Detected in single" 148 "Plasma cells: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 187 "memory B-cell: 6029.7;naive B-cell: 2618.0" "Lineage enriched" "Detected in all" 261 "B-cells: 6029.7" "Cell line enriched" "Detected in some" 87 "U-698: 3990.3" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 7.2 0.0 2.9 0.0 240.0 0.9 10.8 0.0 3.6 377.5 0.0 0.0 0.0 200.2 7.4 4.1 12.3 0.9 2.5 0.0 39.1 0.0 0.0 8.9 30.7 0.0 0.0 13.6 0.0 2.5 22.3 7.0 416.7 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.0 45.4 7.3 3.7 3.1 32.3 3.9 0.0 1568.0 551.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 14.0 17.5 0.0 0.0 0.0 0.0 6.8 3.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 45.8 0.0 0.0 6.2 0.0 3990.3 0.0 12.2 0.0 13.9 3.6 5.4 5.0 1.3 3.0 6029.7 13.2 4.0 23.1 2618.0 1.5 6.0 20.1 3.3 6.0 0.0 6.6 1048.2 7.2 2.9 0.9 10.8 0.9 2.5 8.9 30.7 22.3 2.0 3.1 1.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.5;breast: 73.2;intestine: 72.3;prostate: 32.7" "Cell type enriched" "Detected in single" 397 "Plasma cells: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 263 "memory B-cell: 1081.0" "Lineage enriched" "Detected in many" 263 "B-cells: 1081.0" "Group enriched" "Detected in some" 11 "HL-60: 10.5;REH: 14.0;RH-30: 18.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" 33.5 0.0 0.7 0.0 3.7 0.0 73.2 0.7 2.0 0.0 2.0 72.3 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.9 4.2 4.5 29.4 17.1 0.0 3.1 1.0 0.0 4.7 0.0 0.0 0.0 1.9 32.7 0.2 0.2 0.0 0.0 0.0 7.9 0.0 0.0 1.6 0.0 0.0 0.4 1.3 0.0 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.6 2.1 1.2 0.7 1081.0 0.4 0.6 4.1 0.0 2.6 0.9 2.3 0.7 0.6 0.0 1.1 316.0 0.7 3.7 0.7 2.0 0.9 4.2 3.1 1.0 1.9 1.6 1.3 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 56 "Plasma cells: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cell line enhanced" "Detected in some" "U-266/84: 1.3;U-937: 1.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.9 142.4 0.0 2.6 38.6 1.0 0.0 0.0 2.1 0.5 0.9 0.3 0.0 3.0 2.4 47.0 0.4 0.4 0.1 0.0 0.0 3.7 0.0 0.0 0.3 3.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 151.4 0.3 0.0 0.7 0.0 10.7 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.2 0.0 3.5 3.5 0.8 0.3 0.0 0.2 316.2 0.5 0.6 0.5 112.7 0.6 0.3 14.8 0.2 1.0 0.0 0.1 89.2 0.0 0.0 0.1 0.9 0.3 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1315.0;lymphoid tissue: 4112.3" "Group enriched" "Detected in many" 14 "B-cells: 3757.1;Plasma cells: 9906.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 16 "memory B-cell: 4278.4;naive B-cell: 6731.2" "Lineage enriched" "Detected in all" 19 "B-cells: 6731.2" "Group enriched" "Detected in many" 9 "Daudi: 4983.6;U-698: 4905.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB008643 Uncertain "Immunoglobulin genes" NA NA 110000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" 52.0 9.0 0.4 373.7 0.4 395.3 56.6 0.2 1.7 67.9 1.8 446.8 1204.9 11.1 10.2 66.8 38.5 141.7 50.5 0.2 0.4 48.4 84.7 180.6 3192.1 1.9 0.3 9.7 44.5 0.6 8.7 3.6 0.7 15.1 201.4 0.0 325.1 6.1 2.7 1.7 1315.0 7.9 1.0 4112.3 528.9 70.9 0.7 117.3 37.0 0.7 497.1 128.0 10.5 0.5 4.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 4983.6 2.9 0.0 0.0 0.8 0.0 0.0 0.0 21.6 0.0 3.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 1.7 28.7 1.2 0.0 0.0 580.2 2.2 6.9 0.0 0.0 4.0 5.8 3.0 0.5 1.2 0.0 0.2 3.8 6.5 0.0 13.8 1.2 2.5 1.5 1.5 4905.9 0.0 2.4 0.0 10.8 5.4 5.6 3.1 1.2 2.3 4278.4 5.5 6.8 5.4 6731.2 4.5 3.8 25.4 11.4 4.5 346.1 11.4 815.2 0.4 0.4 0.2 1.7 0.2 0.4 1.9 0.3 0.7 1.0 0.7 0.5 1.0 38.5 254.5 0.0 3757.1 0.0 0.2 0.0 1.2 0.0 2.2 0.8 0.3 31.5 14.2 0.0 0.0 0.0 63.8 1.8 0.0 0.0 0.0 0.0 0.1 4.2 6.7 474.1 0.0 0.0 0.0 10.8 27.5 0.0 152.6 0.0 56.7 147.9 0.1 0.0 0.0 2.2 0.0 158.1 0.0 0.0 0.0 12.4 0.0 0.0 5.2 0.0 11.3 0.0 0.0 0.0 1.2 0.0 9906.5 0.3 0.0 2.2 1.5 0.0 0.0 0.4 16.8 0.0 0.0 0.2 0.0 0.0 415.0 0.3 4.1 0.1 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 76.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 231.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HL-60: 1.8;JURKAT: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 3100000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" 6.8 1.4 0.1 33.7 0.0 0.0 8.5 0.0 0.3 56.3 0.1 30.5 0.0 5.7 0.0 46.2 6.5 4.6 1.8 0.0 0.1 7.0 6.4 17.7 0.0 1.2 0.1 19.6 1.4 0.1 0.4 0.3 0.0 3.1 14.0 0.0 76.3 0.0 0.1 0.8 24.0 2.1 0.0 186.8 37.0 14.2 0.0 0.4 14.5 0.0 18.4 63.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.8 0.1 0.0 0.0 2.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 3.6 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 19.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 231.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 5.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.9;lymphoid tissue: 30.3;stomach 1: 17.5" "Cell type enriched" "Detected in single" 20 "Plasma cells: 2.0" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.3" "Immunoglobulin genes" NA NA 380000000 "Cluster 32: T-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" 0.2 0.1 0.0 3.7 0.0 1.8 18.9 0.0 0.0 0.3 0.0 4.5 1.1 0.5 0.0 6.4 0.2 0.6 0.1 0.0 0.0 0.2 0.2 3.5 7.6 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 6.1 0.0 11.5 0.0 0.0 0.1 2.3 0.7 0.0 6.9 17.5 0.1 0.0 2.9 0.3 0.0 30.3 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 1.1 0.6 0.3 0.0 1.1 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "urinary bladder: 204.7" "Group enriched" "Detected in some" 17 "B-cells: 2.4;Plasma cells: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.7" "Lineage enriched" "Detected in single" 58 "B-cells: 12.7" "Cell line enhanced" "Detected in single" "MOLT-4: 1.5" "Immunoglobulin genes" NA NA 120000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (9.63e-3)" "unprognostic (6.78e-2)" "unprognostic (5.64e-2)" "unprognostic (4.04e-2)" "prognostic favorable (7.25e-4)" "unprognostic (4.56e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-1)" "unprognostic (1.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "unprognostic (6.79e-2)" "unprognostic (1.36e-1)" 8.1 3.4 0.0 13.8 0.0 5.9 3.8 0.0 0.0 0.8 0.0 19.5 15.7 0.4 0.0 8.3 1.1 4.7 1.0 0.0 0.0 1.5 1.4 5.4 41.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 27.8 0.0 23.5 1.9 0.0 0.2 9.8 0.1 0.0 26.2 13.1 0.5 0.0 10.3 1.1 0.0 51.1 204.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 85 "Plasma cells: 231.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0;MOLT-4: 6.2;SCLC-21H: 1.1;U-698: 1.9" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" 7.7 1.4 0.0 0.0 0.1 0.1 6.5 0.0 0.0 21.4 0.1 56.9 0.0 6.9 0.0 7.0 5.7 77.4 0.7 0.0 0.1 7.0 4.8 18.0 0.0 2.5 0.0 2.0 0.8 1.8 0.5 0.0 3.0 4.6 139.1 0.0 55.9 13.0 0.1 0.5 31.7 6.8 0.0 170.2 31.0 0.1 0.0 0.0 25.2 0.0 0.0 162.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 1.3 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1;lymphoid tissue: 47.1" "Cell type enriched" "Detected in some" 226 "Plasma cells: 10423.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cell line enriched" "Detected in some" 6 "MOLT-4: 11.2" "Immunoglobulin genes" NA NA 1100000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 6.3 0.3 0.0 5.8 0.0 2.5 3.6 0.0 0.0 1.5 0.0 12.0 22.1 1.1 0.2 2.1 1.2 14.5 1.6 0.0 0.0 2.7 0.9 4.5 13.5 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 14.4 0.0 16.4 0.9 0.0 0.0 18.0 0.2 0.0 47.1 9.9 0.2 0.0 3.7 1.1 0.0 36.5 4.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 6.7 0.5 0.9 0.0 5.5 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 1.4 23.0 0.0 0.0 0.0 1.1 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10423.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV1OR15-1 IGHV1/OR15-1 ENSG00000270505 "Immunoglobulin heavy variable 1/OR15-1 (non-functional)" 15 22160431-22160868 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 78.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.0;B-cells: 1.1;granulocytes: 1.3;T-cells: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 94.3;naive B-cell: 111.6" "Group enriched" "Detected in many" 18 "B-cells: 111.6;T-cells: 60.9" "Group enriched" "Detected in some" 4 "JURKAT: 10.3;Karpas-707: 6.9;MOLT-4: 2.5" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.14e-1)" "unprognostic (1.13e-1)" 0.6 0.4 0.0 18.2 0.1 7.0 5.8 0.1 0.1 0.8 0.0 15.6 13.8 0.8 0.0 4.0 0.6 14.4 0.6 0.0 0.1 0.4 0.7 2.8 52.0 0.2 0.1 1.0 0.4 0.1 0.1 0.1 0.1 2.3 10.2 0.0 4.8 0.4 0.0 0.1 13.7 0.4 0.2 18.1 11.1 0.1 0.1 58.7 1.1 0.0 78.8 9.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 6.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 9.2 0.0 3.3 94.3 54.9 18.1 0.1 111.6 60.9 14.5 0.5 4.8 0.1 3.3 35.9 20.5 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.0 3.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 IGHV1OR15-9 "IGHV1/OR15-9, IGHV1OR159, VSIG7" ENSG00000188403 "Immunoglobulin heavy variable 1/OR15-9 (non-functional)" 15 19964666-19965101 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "breast: 4.1;intestine: 8.6;lymphoid tissue: 8.6;stomach 1: 8.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: B-cells - Humoral immune response" "prognostic favorable (1.79e-4)" "unprognostic (8.93e-2)" "unprognostic (2.97e-3)" "unprognostic (9.34e-2)" "prognostic favorable (6.84e-4)" "unprognostic (1.64e-1)" "unprognostic (1.57e-1)" "unprognostic (3.79e-1)" "unprognostic (1.07e-4)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (2.66e-1)" "unprognostic (2.11e-1)" 0.0 0.0 0.0 8.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 8.6 3.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 8.3 0.0 0.0 1.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1OR21-1 IGHV1/OR21-1 ENSG00000277282 "Immunoglobulin heavy variable 1/OR21-1 (non-functional)" 21 10649400-10649835 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 6.3;stomach 1: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 2.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "memory B-cell: 2.0;naive B-cell: 1.7" "Lineage enriched" "Detected in single" 15 "B-cells: 2.0" "Cell line enhanced" "Detected in single" "U-266/70: 1.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "unprognostic (3.93e-3)" "unprognostic (2.55e-2)" "unprognostic (1.28e-2)" "unprognostic (8.48e-5)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (3.32e-1)" 0.0 0.6 0.0 3.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 3.3 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 1.4 0.6 0.0 0.9 3.4 0.1 0.0 0.5 0.0 0.0 6.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 128.8;lymphoid tissue: 98.5;urinary bladder: 227.1" "Group enriched" "Detected in some" 39 "B-cells: 8.3;Plasma cells: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 13.9" "Lineage enriched" "Detected in single" 140 "B-cells: 13.9" "Cell line enhanced" "Detected in some" "HL-60: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 190000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 57: B-cells - Immune response" "unprognostic (9.39e-3)" "unprognostic (4.50e-2)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (4.99e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "unprognostic (2.24e-1)" "unprognostic (8.09e-2)" 6.2 7.7 0.0 59.0 0.0 21.6 14.0 0.0 0.3 15.5 0.2 35.0 61.5 4.2 0.0 31.5 3.8 128.8 5.6 0.0 0.4 2.3 6.0 20.7 3.5 0.2 0.6 0.5 1.6 0.0 0.3 0.0 0.1 6.3 86.5 0.0 44.2 0.9 0.1 0.5 55.1 4.4 0.2 98.5 65.1 0.0 1.1 0.0 6.8 0.0 21.8 227.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.2 1.1 0.2 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 727.6;stomach 1: 502.1" "Cell type enriched" "Detected in single" 5 "Plasma cells: 2.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Group enriched" "Detected in some" 241 "memory B-cell: 24.6;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 247 "B-cells: 24.6" "Cell line enriched" "Detected in some" 8 "U-698: 12.4" "Immunoglobulin genes" NA NA 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.01e-3)" "unprognostic (2.93e-2)" "unprognostic (3.56e-3)" "unprognostic (2.38e-2)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (9.10e-2)" "unprognostic (2.50e-1)" "unprognostic (8.93e-2)" "unprognostic (2.91e-1)" 7.3 25.7 0.0 96.2 0.0 69.2 86.1 0.0 5.2 62.3 0.0 86.7 53.2 4.1 0.0 44.3 8.1 37.5 2.5 0.0 1.4 4.8 13.2 69.9 82.7 0.1 1.1 5.0 1.0 0.9 0.3 0.2 0.1 6.8 82.8 0.0 94.5 14.1 0.1 0.9 42.1 2.5 2.2 156.4 502.1 1.2 0.0 59.5 8.5 0.0 727.6 50.4 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.4 0.8 0.0 0.0 0.8 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.7 0.0 0.1 0.0 12.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 5.2 0.0 1.4 0.1 1.1 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.8;lymphoid tissue: 90.8;stomach 1: 47.0" "Cell type enriched" "Detected in single" 10 "B-cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 97 "B-cells: 9.7" "Cell line enriched" "Detected in single" 7 "MOLT-4: 1.7" "Immunoglobulin genes" NA NA 110000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.57e-2)" "unprognostic (9.48e-3)" "prognostic favorable (3.34e-4)" "unprognostic (4.34e-2)" "unprognostic (8.37e-3)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.70e-2)" "unprognostic (3.83e-1)" "unprognostic (3.66e-2)" "unprognostic (8.11e-2)" 1.7 0.7 0.0 16.6 0.0 4.1 7.1 0.0 0.0 5.6 0.1 36.8 14.2 1.9 0.0 5.2 4.5 20.9 1.7 0.0 0.0 2.5 2.3 6.2 4.6 0.0 0.0 0.8 0.3 0.1 0.1 0.0 0.0 0.7 33.1 0.0 30.3 0.1 0.0 0.1 21.7 0.6 0.0 41.4 47.0 0.0 0.0 4.5 2.5 0.0 90.8 3.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.5;lymphoid tissue: 137.3;urinary bladder: 90.5" "Group enriched" "Detected in some" 6 "B-cells: 6.7;Plasma cells: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 193 "memory B-cell: 18.8;naive B-cell: 19.6" "Lineage enriched" "Detected in single" 197 "B-cells: 19.6" "Cell line enhanced" "Detected in some" "MOLT-4: 1.8;U-266/70: 1.0" "Immunoglobulin genes" NA NA 33000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (3.24e-4)" "unprognostic (7.42e-2)" "unprognostic (1.96e-2)" "unprognostic (5.03e-2)" "prognostic favorable (6.67e-6)" "unprognostic (5.44e-2)" "unprognostic (1.23e-2)" "unprognostic (1.53e-1)" "unprognostic (5.31e-2)" "unprognostic (8.27e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.21e-5)" "unprognostic (6.79e-2)" "unprognostic (3.21e-1)" "unprognostic (4.45e-1)" "unprognostic (7.87e-2)" 1.3 36.6 0.0 24.1 0.0 6.9 17.2 0.0 0.1 1.9 0.0 67.5 49.5 1.5 0.0 15.4 4.3 9.7 1.8 0.0 0.0 1.1 1.5 7.2 39.5 0.0 0.1 1.5 0.7 0.0 0.1 0.0 0.0 1.1 36.1 0.0 30.9 1.4 0.0 0.1 22.8 5.6 0.1 56.5 42.9 0.9 0.0 9.3 2.8 0.0 137.3 90.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-16 ENSG00000211944 "Immunoglobulin heavy variable 3-16 (non-functional)" A0A0C4DH30 14 106165205-106165730 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 3200000000 "Cluster 43: B-cells - Humoral immune response" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 14.1;lymphoid tissue: 12.8;salivary gland: 7.6;stomach 1: 16.7;urinary bladder: 20.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Cell line enriched" "Detected in single" 6 "MOLT-4: 1.3" "Immunoglobulin genes" NA NA 19000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" 0.1 0.1 0.0 12.8 0.0 3.3 1.1 0.0 0.0 2.8 0.0 10.3 14.1 0.4 0.0 0.5 1.1 1.1 0.5 0.0 0.0 0.1 0.7 2.4 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 11.1 0.0 7.6 0.5 0.0 0.2 6.0 0.6 0.0 5.3 16.7 0.0 0.0 0.0 0.0 0.0 2.2 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-38 ENSG00000211958 "Immunoglobulin heavy variable 3-38 (non-functional)" A0A0C4DH36 14 106410493-106411021 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.9;lymphoid tissue: 10.4;stomach 1: 5.9;urinary bladder: 7.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.4;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 34 "B-cells: 3.4" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.03e-5)" "unprognostic (5.11e-2)" "unprognostic (3.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.31e-3)" "unprognostic (8.40e-2)" "unprognostic (3.54e-2)" "unprognostic (2.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.75e-8)" "unprognostic (6.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.99e-1)" "unprognostic (2.52e-1)" 0.3 0.1 0.0 5.9 0.0 1.6 3.3 0.0 0.0 1.4 0.0 7.7 9.9 0.1 0.0 0.9 0.1 0.9 0.2 0.0 0.0 0.1 0.4 1.8 2.2 0.0 0.0 0.6 0.4 0.0 0.0 0.2 0.0 0.2 7.0 0.0 4.1 0.0 0.0 0.2 5.8 0.0 0.0 4.4 5.9 0.7 0.0 0.0 0.0 0.0 10.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-64 ENSG00000223648 "Immunoglobulin heavy variable 3-64" A0A075B6Q5 14 106657725-106658258 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;lymphoid tissue: 32.1;salivary gland: 21.0" "Cell type enriched" "Detected in some" 38 "Plasma cells: 88.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "memory B-cell: 11.1" "Lineage enriched" "Detected in single" 111 "B-cells: 11.1" "Cell line enhanced" "Detected in single" "HL-60: 1.1" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.09e-6)" "unprognostic (6.52e-2)" "unprognostic (2.11e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-3)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (8.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.33e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (3.93e-5)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.07e-2)" 1.7 0.1 0.0 2.0 0.0 8.6 7.2 0.0 0.4 0.7 0.0 17.9 6.9 0.9 0.0 1.2 1.9 4.1 1.2 0.0 0.0 0.8 2.2 4.3 0.0 0.1 0.0 3.3 3.6 0.0 0.1 0.0 0.0 0.5 1.2 0.0 21.0 0.4 0.0 0.1 11.3 1.3 0.0 32.1 6.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: Non-specific - Mitochondria" 8.3 0.5 0.2 140.3 0.1 10.9 84.2 0.0 0.8 12.9 0.3 130.9 20.4 3.3 1.4 35.4 7.8 46.3 4.8 0.5 0.0 1.5 4.2 36.7 48.8 0.1 0.0 5.1 8.1 0.1 0.1 0.1 0.0 4.1 145.2 0.0 28.9 11.5 0.0 3.8 68.8 3.6 0.1 67.4 74.8 0.5 0.0 16.5 2.9 0.0 272.7 40.5 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790691-106791233 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.7;lymphoid tissue: 121.6;urinary bladder: 101.3" "Cell type enriched" "Detected in some" 271 "Plasma cells: 3507.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "memory B-cell: 52.4" "Lineage enriched" "Detected in many" 50 "B-cells: 52.4" "Cell line enhanced" "Detected in some" "NB-4: 1.3;RH-30: 1.3;RPMI-8226: 1.2;TIME: 2.2;U-698: 5.8" "Immunoglobulin genes" NA NA 9600000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" 4.8 2.6 0.1 18.4 0.1 15.5 7.0 0.0 0.6 5.2 0.1 75.7 28.4 3.0 2.9 17.4 3.4 0.3 0.3 0.0 0.0 1.9 5.3 8.6 2.7 0.5 0.0 2.3 3.4 0.1 0.2 0.1 0.1 1.9 47.6 0.0 46.6 0.9 0.1 0.3 58.2 5.4 0.1 121.6 29.4 0.0 0.0 2.6 2.2 0.5 12.1 101.3 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.3 0.2 0.0 0.0 0.1 1.3 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.1 0.0 0.3 0.0 5.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 52.4 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.1 0.0 0.6 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.1 7.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3507.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Cholangiocytes: 1.5;Erythroid cells: 5.3;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cell line enhanced" "Detected in some" "Daudi: 1.4;HEL: 1.1;HL-60: 1.1;K-562: 1.7" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" 4.4 13.3 0.0 9.4 0.0 15.8 10.5 0.0 0.5 4.7 0.3 76.9 141.8 5.1 0.0 4.0 3.9 19.1 10.4 0.0 0.0 3.0 9.8 12.3 0.0 0.1 0.0 1.5 5.9 0.0 0.5 0.1 0.2 4.3 58.0 0.0 30.6 3.9 0.4 0.2 23.6 0.4 0.1 83.0 47.5 0.4 0.0 0.0 4.1 0.0 0.2 81.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 69.9 0.1 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.9;lymphoid tissue: 327.0;salivary gland: 102.6" "Cell type enriched" "Detected in some" 454 "Plasma cells: 19404.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 861 "Daudi: 2948.0" "Immunoglobulin genes" NA NA 27000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.47e-4)" "unprognostic (9.70e-2)" "prognostic favorable (8.33e-4)" "unprognostic (6.96e-3)" "unprognostic (1.42e-1)" "prognostic favorable (7.79e-4)" "unprognostic (1.06e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-1)" "unprognostic (3.07e-2)" "unprognostic (2.42e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (4.70e-6)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" 11.3 1.2 0.1 0.0 0.2 0.0 12.6 0.0 1.5 9.3 0.0 103.9 0.0 2.1 1.9 87.3 2.6 1.3 0.7 0.0 0.3 4.7 6.6 22.2 0.0 0.6 0.0 2.5 1.9 0.6 0.8 0.1 0.2 6.5 0.0 0.0 102.6 0.0 0.5 3.2 74.1 0.0 0.3 327.0 27.5 0.2 0.1 0.0 7.7 0.0 0.0 46.4 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 2948.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.1 1.1 0.2 0.0 0.0 0.1 1.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.7 0.3 0.4 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.5 0.0 0.3 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 42.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 1.4 27.5 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 19404.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 2.3 0.0 0.1 0.3 IGHV3OR15-7 IGHV3/OR15-7 ENSG00000259490 "Immunoglobulin heavy variable 3/OR15-7 (pseudogene)" 15 19987656-19988117 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 2.0;stomach 1: 1.8" "Cell type enriched" "Detected in single" 104 "Plasma cells: 10.4" "Cancer enhanced" "Detected in many" "lung cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.08e-2)" "unprognostic (8.21e-2)" "unprognostic (1.08e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.43e-5)" "unprognostic (4.56e-1)" "unprognostic (3.12e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-4)" "unprognostic (7.46e-2)" "unprognostic (1.35e-1)" "unprognostic (3.50e-1)" "unprognostic (1.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-10 IGHV3/OR16-10 ENSG00000233732 "Immunoglobulin heavy variable 3/OR16-10 (non-functional)" 16 32995048-32995505 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 4.8;intestine: 6.3;lymphoid tissue: 8.3;salivary gland: 7.0;stomach 1: 5.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.1" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.40e-3)" "unprognostic (4.22e-2)" "unprognostic (3.45e-2)" "unprognostic (3.41e-4)" "unprognostic (2.20e-1)" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" 0.0 0.2 0.0 1.0 0.0 1.1 0.7 0.2 0.3 0.0 0.0 4.1 6.2 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.3 0.0 7.0 0.0 0.0 0.0 2.1 1.1 0.1 1.4 5.6 3.5 0.1 0.9 0.2 0.0 8.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.4 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-12 IGHV3/OR16-12 ENSG00000270467 "Immunoglobulin heavy variable 3/OR16-12 (non-functional)" 16 33802764-33803217 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 13.7;lymphoid tissue: 20.3;stomach 1: 9.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "memory B-cell: 4.5" "Lineage enriched" "Detected in single" 46 "B-cells: 4.5" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (2.04e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-3)" "unprognostic (1.07e-1)" "unprognostic (7.10e-2)" "unprognostic (5.02e-1)" "unprognostic (1.29e-1)" 0.0 0.0 0.0 7.7 0.0 1.0 3.3 0.0 0.0 1.2 0.0 8.3 13.7 0.0 0.0 1.1 0.1 1.6 0.0 0.0 0.0 0.1 0.3 1.3 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 4.1 0.0 2.5 0.0 0.0 0.0 3.6 0.0 0.0 2.1 9.8 0.2 0.0 1.0 0.0 0.0 20.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "stomach cancer: 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "memory B-cell: 18.1" "Lineage enriched" "Detected in single" 181 "B-cells: 18.1" "Cell line enriched" "Detected in some" 818 "Daudi: 1604.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.59e-4)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.23e-5)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-5)" "unprognostic (6.83e-2)" "unprognostic (1.71e-1)" "unprognostic (3.09e-1)" "unprognostic (3.04e-1)" 0.2 0.0 0.1 5.3 0.0 0.6 0.4 0.0 0.1 1.3 0.0 6.7 6.0 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.0 7.0 0.0 0.0 0.0 4.0 0.1 0.0 32.2 4.2 0.0 0.0 1.0 0.3 0.0 10.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1604.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-17 IGHV3/OR16-17 ENSG00000259680 "Immunoglobulin heavy variable 3/OR16-17 (non-functional)" 16 33844784-33845229 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 11.5;lymphoid tissue: 24.4;stomach 1: 11.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "memory B-cell: 1.5;naive B-cell: 2.5" "Lineage enriched" "Detected in single" 26 "B-cells: 2.5" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.57e-3)" "unprognostic (1.35e-2)" "unprognostic (5.32e-2)" "prognostic favorable (6.96e-5)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-3)" "unprognostic (7.52e-2)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (3.58e-1)" 0.2 0.1 0.0 9.3 0.0 4.3 3.3 0.0 0.0 4.0 0.0 11.5 9.6 0.1 0.0 4.0 0.1 0.5 1.0 0.0 0.0 0.0 0.4 1.0 1.3 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 6.4 0.0 4.3 0.0 0.0 0.0 5.6 0.4 0.0 4.1 11.8 0.0 0.0 0.5 0.0 0.0 24.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-8 IGHV3/OR16-8 ENSG00000271130 "Immunoglobulin heavy variable 3/OR16-8 (non-functional)" 16 33009175-33009620 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 32.0;lymphoid tissue: 49.4;stomach 1: 32.9;urinary bladder: 40.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "memory B-cell: 7.3" "Lineage enriched" "Detected in single" 74 "B-cells: 7.3" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (2.58e-4)" "unprognostic (3.25e-2)" "unprognostic (9.53e-3)" "unprognostic (1.56e-1)" "unprognostic (2.43e-4)" "unprognostic (1.31e-1)" "unprognostic (4.47e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (2.60e-7)" "unprognostic (2.24e-2)" "unprognostic (4.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.16e-2)" 2.3 0.8 0.0 13.8 0.0 5.9 4.5 0.0 0.0 2.7 0.0 30.1 32.0 0.2 0.0 1.9 0.7 5.3 0.0 0.0 0.0 0.1 0.9 3.2 3.6 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 14.8 0.0 10.0 0.0 0.0 0.0 9.0 1.8 0.0 5.8 32.9 0.1 0.0 3.0 0.7 0.0 49.4 40.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-9 IGHV3/OR16-9 ENSG00000270472 "Immunoglobulin heavy variable 3/OR16-9 (non-functional)" 16 32066065-32066358 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 73.2;lymphoid tissue: 88.5;stomach 1: 79.0;urinary bladder: 54.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 136 "memory B-cell: 20.0;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 200 "B-cells: 20.0" "Not detected" "Not detected" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.32e-3)" "unprognostic (8.31e-2)" "unprognostic (2.49e-3)" "prognostic favorable (1.29e-4)" "unprognostic (2.29e-1)" "unprognostic (5.22e-2)" "unprognostic (1.91e-1)" "unprognostic (1.31e-1)" "unprognostic (1.01e-5)" "unprognostic (1.57e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "unprognostic (1.55e-1)" 11.1 9.8 0.1 32.9 0.0 13.7 17.1 0.3 0.6 8.3 0.0 73.2 45.8 0.9 0.0 26.5 1.5 8.3 2.9 0.0 0.1 0.8 3.7 9.1 13.0 0.6 0.0 6.2 1.3 0.1 0.0 0.0 0.4 1.1 37.7 0.0 49.3 0.0 0.0 0.0 38.6 0.3 0.4 27.0 79.0 0.3 0.1 8.6 0.1 0.0 88.5 54.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.3 0.6 0.0 0.1 0.6 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV4OR15-8 "IGHV4/OR15-8, IGHV4OR158, VSIG6" ENSG00000259261 "Immunoglobulin heavy variable 4/OR15-8 (non-functional)" 15 22184967-22185402 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lymphoid tissue: 1.4;urinary bladder: 2.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "stomach cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.68e-3)" "unprognostic (9.63e-2)" "unprognostic (1.17e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 1.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in single" 36 "B-cells: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 6 "Daudi: 9.4;U-698: 4.8" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA006014: " 4.5 28.4 0.0 229.8 0.0 38.7 102.0 0.0 0.9 68.9 0.1 274.0 0.9 10.8 0.0 111.5 20.0 92.5 6.2 0.0 0.0 5.5 7.3 128.3 121.2 0.1 0.0 54.0 5.7 0.4 0.3 0.2 0.2 6.9 316.6 0.0 75.5 19.0 0.1 1.6 51.6 10.9 0.0 203.8 148.3 0.1 0.0 39.3 7.3 0.0 568.1 196.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 4.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 66.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGHV7-4-1 ENSG00000282122 "Immunoglobulin heavy variable 7-4-1" A0A0J9YVY3 14 106025145-106025630 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.4;lymphoid tissue: 133.9" "Cell type enriched" "Detected in some" 4 "Plasma cells: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 109 "memory B-cell: 8.3;naive B-cell: 13.5" "Lineage enriched" "Detected in single" 136 "B-cells: 13.5" "Cell line enriched" "Detected in some" 5 "Karpas-707: 5.4" "Immunoglobulin genes" NA NA 560000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" 3.9 2.9 0.3 58.3 0.0 39.0 21.1 0.0 0.6 7.7 0.2 60.8 8.3 0.5 0.0 4.7 0.8 3.1 0.8 0.0 0.0 2.1 2.8 49.1 7.5 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.0 2.6 97.4 0.0 42.2 8.7 0.3 0.2 42.9 0.2 0.1 68.5 24.2 0.2 0.0 45.6 5.9 0.0 133.9 10.4 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV7-81 ENSG00000211979 "Immunoglobulin heavy variable 7-81 (non-functional)" A0A0B4J1V7 14 106874583-106875071 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;lymphoid tissue: 18.3;stomach 1: 12.3" "Group enriched" "Detected in some" 12 "B-cells: 1.5;Plasma cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 5.5;naive B-cell: 3.9" "Lineage enriched" "Detected in single" 14 "B-cells: 5.5" "Cell line enhanced" "Detected in some" "A549: 1.1;Daudi: 6.1;OE19: 1.2;U-698: 2.0" "Immunoglobulin genes" NA NA 270000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (5.71e-4)" "unprognostic (3.87e-1)" "unprognostic (1.06e-1)" "unprognostic (6.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.24e-1)" "unprognostic (2.07e-1)" "unprognostic (1.14e-2)" "unprognostic (6.16e-5)" "unprognostic (1.69e-3)" "unprognostic (1.78e-2)" "unprognostic (1.08e-1)" "unprognostic (5.63e-2)" "unprognostic (3.44e-1)" "unprognostic (3.63e-2)" 0.1 0.1 0.0 8.4 0.0 4.6 3.6 0.0 0.0 0.3 0.0 7.6 6.4 0.4 0.0 0.6 0.3 7.9 0.2 0.0 0.0 0.3 0.2 1.8 4.2 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 2.3 12.7 0.0 5.0 0.1 0.0 0.2 6.2 0.4 0.0 2.3 12.3 0.1 0.0 1.4 0.0 0.0 18.3 1.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.5 0.3 0.1 0.0 3.9 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV8-51-1 "IGHV(III)-51-1, IGHVIII-51-1" ENSG00000254167 "Immunoglobulin heavy variable IGHV8-51-1 (non-functional)" 14 106583501-106583807 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "MOLT-4: 10.8" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 12 "B-cells: 72318.1;Plasma cells: 96515.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Group enriched" "Detected in many" 6 "Daudi: 9909.1;U-266/70: 10337.6;U-266/84: 3927.9;U-698: 12154.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" 1025.4 2379.8 13.1 20500.0 13.3 6315.2 11287.7 11.3 33.6 3649.2 26.7 35196.7 24515.5 877.3 474.1 5708.4 1137.6 5995.3 810.4 11.4 16.7 1176.6 1580.5 5824.2 21356.1 25.1 18.2 2214.9 462.9 72.6 101.8 22.2 15.3 843.6 30618.3 4.0 19606.1 2123.2 32.9 250.8 17061.1 1259.7 43.5 26904.1 22740.5 1083.9 13.4 8576.0 2151.1 8.1 63075.6 24817.5 705.0 20.2 17.1 0.0 0.0 0.0 0.0 0.0 103.7 0.0 0.0 0.1 0.0 0.0 0.0 9909.1 15.3 0.0 1.0 22.2 0.0 0.0 0.0 510.2 0.0 30.9 0.0 0.0 0.0 67.8 29.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.8 0.4 0.0 0.0 18.3 83.2 28.8 0.0 0.0 16.7 56.4 1509.5 0.6 0.0 79.6 146.1 19.6 1.5 6.0 0.5 0.5 17.2 66.7 0.0 56.9 24.3 44.0 10337.6 3927.9 12154.4 0.0 28.9 0.0 47.5 55.6 31.6 24.6 11.2 21.7 39143.0 28.3 18.3 46.6 35081.5 15.2 16.8 65.2 24.1 29.1 1735.4 23.7 8567.0 13.1 13.3 11.3 33.6 11.4 16.7 25.1 18.2 15.3 43.5 13.4 20.2 58.6 336.5 1863.8 0.0 72318.1 0.0 189.2 0.0 2.2 0.0 8.8 7.0 5.7 163.0 88.5 0.0 0.0 48.0 452.1 39.8 3.9 0.0 2.8 0.7 0.3 72.8 77.8 1658.9 0.0 0.2 37.3 186.5 64.7 0.4 849.0 15.5 340.2 334.8 8.9 0.0 0.0 35.1 0.0 496.3 0.0 11.0 0.0 64.4 0.0 0.0 26.4 0.0 59.8 0.0 0.0 0.0 25.9 0.4 96515.7 193.2 0.3 45.2 12.4 0.0 0.0 3.7 38.4 0.3 0.2 5.9 0.0 49.4 6505.3 0.1 50.2 1.9 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2670.6;lymphoid tissue: 2226.1;salivary gland: 1187.7;stomach 1: 1719.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22200.6;naive B-cell: 20663.6" "Lineage enriched" "Detected in all" 52 "B-cells: 22200.6" "Group enriched" "Detected in many" 7 "HDLM-2: 213.9;RPMI-8226: 179.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" 67.9 154.0 0.6 1862.6 0.9 296.5 312.9 0.1 4.0 158.7 0.7 1762.7 2670.6 37.5 0.0 308.3 14.3 114.1 19.6 0.6 0.6 27.0 61.7 236.7 693.3 4.3 1.4 71.6 72.5 1.9 0.0 1.1 1.2 46.0 1364.3 0.0 1187.7 20.2 2.9 5.2 1974.3 28.2 1.5 1097.1 1719.7 44.8 0.9 73.5 5.1 0.0 2226.1 494.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 3.5 0.0 0.0 0.0 213.9 0.0 9.7 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 8.0 3.6 0.0 0.0 7.4 2.5 179.1 0.0 0.0 3.2 17.5 4.8 0.0 0.0 0.0 0.0 29.6 10.7 0.0 3.4 3.7 7.6 5.3 0.0 29.0 0.0 1.8 0.0 19.7 33.6 12.8 10.3 7.7 12.8 22200.6 15.0 8.1 23.3 20663.6 9.5 9.6 42.6 10.8 18.6 430.3 17.4 2451.2 0.6 0.9 0.1 4.0 0.6 0.6 4.3 1.4 1.2 1.5 0.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 1010.8;lymphoid tissue: 997.2;stomach 1: 710.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 12 "spinal cord: 18.3" "Group enriched" "Detected in all" 26 "memory B-cell: 8663.4;naive B-cell: 7153.9" "Lineage enriched" "Detected in all" 28 "B-cells: 8663.4" "Group enriched" "Detected in some" 6 "HDLM-2: 105.2;RPMI-8226: 89.2;U-698: 41.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 15.1 19.6 0.8 886.7 0.7 115.0 111.2 0.3 1.3 19.2 0.5 587.3 1010.8 7.6 0.0 68.8 7.9 44.8 9.3 0.9 0.6 14.3 41.1 101.9 490.2 1.2 0.5 31.1 0.0 0.0 0.0 1.9 1.5 18.2 546.6 0.6 362.3 12.6 8.7 2.5 726.3 19.9 18.3 548.6 710.1 9.7 0.9 53.9 5.1 3.9 997.2 236.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 105.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 89.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 0.0 0.0 41.2 0.0 0.0 0.0 17.0 8.6 57.9 1.9 1.1 9.2 8663.4 3.0 3.3 5.9 7153.9 5.7 5.1 61.8 7.1 15.2 309.9 7.8 660.0 0.8 0.7 0.3 1.3 0.9 0.6 1.2 0.5 1.5 18.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3282.9;lymphoid tissue: 2905.5;stomach 1: 2295.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36413.7;naive B-cell: 27723.7" "Lineage enriched" "Detected in all" 48 "B-cells: 36413.7" "Cell line enhanced" "Detected in some" "BEWO: 16.9;Daudi: 23.5;HDLM-2: 58.4;RPMI-8226: 43.3;SH-SY5Y: 27.6;U-698: 25.7" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 80.0 268.7 0.6 2905.5 0.7 407.6 414.6 0.3 4.1 110.0 0.5 1844.1 3282.9 29.5 62.5 433.0 33.3 138.1 34.8 0.6 1.1 48.2 104.6 481.3 932.6 2.9 0.7 117.5 29.3 1.7 0.0 1.3 1.3 56.4 1849.6 0.3 1142.3 54.8 3.9 17.3 2184.0 78.1 2.6 1246.0 2295.9 39.7 1.8 113.5 11.4 0.0 2661.5 645.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.0 9.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 2.0 10.4 0.0 0.0 0.0 0.0 9.1 43.3 0.0 0.0 6.7 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.3 8.5 3.3 0.0 25.7 0.0 0.0 0.0 114.4 64.9 20.3 24.9 9.5 16.8 36413.7 15.8 15.2 32.5 27723.7 22.7 16.1 60.0 21.5 25.4 759.9 22.8 3519.3 0.6 0.7 0.3 4.1 0.6 1.1 2.9 0.7 1.3 2.6 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Cell type enriched" "Detected in single" 13 "B-cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Cell line enriched" "Detected in some" 24 "U-698: 3392.4" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" 25.2 42.2 0.5 1365.8 0.7 164.5 236.5 0.6 4.5 73.7 0.3 1194.4 1221.3 13.4 5.8 130.7 8.8 78.5 26.1 0.9 0.7 18.0 30.8 157.6 529.7 1.6 0.6 63.3 29.2 6.6 0.0 4.1 1.2 22.8 1171.9 0.0 643.7 17.1 0.0 5.8 1078.7 40.6 4.9 672.7 1066.6 12.4 0.7 61.5 4.3 0.0 1213.5 436.6 0.0 0.9 17.7 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 142.3 0.0 0.0 0.0 0.0 0.0 7.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 58.5 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.3 3.5 11.4 3.2 1.9 3392.4 0.0 8.1 0.0 3.3 10.1 10.2 3.8 1.3 2.2 9254.1 18.4 3.5 7.4 8737.5 9.5 3.4 9.4 7.6 3.4 373.6 8.8 1167.3 0.5 0.7 0.6 4.5 0.9 0.7 1.6 0.6 1.2 4.9 0.7 0.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.2;lymphoid tissue: 17.2;urinary bladder: 5.6" "Cell type enriched" "Detected in some" 24 "Plasma cells: 73.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 247 "memory B-cell: 21.2;naive B-cell: 28.2" "Lineage enriched" "Detected in single" 283 "B-cells: 28.2" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" 0.1 0.2 0.0 2.9 0.0 0.8 2.4 0.0 0.0 0.5 0.0 4.5 3.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.4 1.2 2.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 2.6 0.6 0.0 0.0 2.0 0.2 0.0 3.7 1.5 0.0 0.0 0.9 0.1 0.0 17.2 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 141 "Plasma cells: 6195.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cell line enhanced" "Detected in single" "Daudi: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" 4.8 0.4 0.0 101.2 0.0 34.8 34.3 0.0 0.0 46.6 0.0 85.6 21.7 5.4 0.0 17.9 10.2 2.5 3.5 0.0 0.0 8.1 6.4 39.4 317.6 0.0 0.0 1.0 1.9 0.0 0.4 0.0 0.1 3.1 78.3 0.0 54.2 1.4 0.0 1.1 103.7 6.8 0.0 102.8 20.3 2.7 0.0 29.0 7.2 0.0 223.2 45.9 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.1 0.2 480.8 0.2 0.1 0.5 331.6 0.0 0.0 0.4 0.1 0.1 0.2 0.1 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6195.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 79.1;intestine: 92.0;lymphoid tissue: 165.5" "Cell type enriched" "Detected in some" 249 "Plasma cells: 1994.1" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 327 "memory B-cell: 57.6;naive B-cell: 120.1" "Lineage enriched" "Detected in single" 442 "B-cells: 120.1" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 9000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" 2.4 0.4 0.0 30.2 0.0 15.0 18.9 0.0 0.4 11.0 0.1 92.0 39.0 1.6 0.0 13.8 2.5 79.1 1.3 0.0 0.0 1.7 3.9 10.0 27.5 0.0 0.0 2.5 0.9 0.6 0.1 0.0 0.1 3.6 50.3 0.0 30.3 0.9 0.0 0.2 34.4 1.0 0.3 56.6 26.7 0.4 0.0 9.9 2.7 0.0 165.5 23.5 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 57.6 0.0 0.0 0.1 120.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1994.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGKV1D-17 ENSG00000242766 "Immunoglobulin kappa variable 1D-17" A0A075B6S4 2 90082635-90083291 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 6.8;lymphoid tissue: 12.5;salivary gland: 5.7" "Cell type enriched" "Detected in some" 13 "Plasma cells: 36.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 60 "memory B-cell: 7.7;naive B-cell: 4.1" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 1000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.47e-4)" "unprognostic (4.23e-2)" "unprognostic (2.43e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.19e-1)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-5)" "unprognostic (1.38e-1)" "unprognostic (1.56e-2)" "unprognostic (1.17e-1)" "unprognostic (4.04e-3)" 1.3 0.1 0.1 5.1 0.1 0.9 0.8 0.1 0.2 0.3 0.8 6.8 1.5 0.2 0.0 0.5 0.8 0.6 0.0 0.1 0.1 0.3 0.4 1.5 0.8 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 2.2 0.0 5.7 0.3 0.0 0.4 4.7 0.4 0.1 12.5 2.0 0.0 0.1 0.3 0.5 0.0 4.5 1.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 410 "Plasma cells: 5131.4" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" 2.8 0.5 0.0 3.8 0.1 2.3 8.3 0.0 0.1 3.6 0.1 32.7 1.3 1.4 0.0 4.6 2.7 2.6 0.2 0.2 0.2 4.0 2.2 17.9 6.8 0.0 0.2 0.4 0.5 0.0 0.1 0.0 0.0 1.6 2.0 0.0 73.3 8.6 0.0 0.5 19.1 0.0 0.5 63.0 21.2 0.1 0.0 4.7 3.3 0.2 9.1 16.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5131.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 IGKV1D-37 "IGKV1D37, O4" ENSG00000250036 "Immunoglobulin kappa variable 1D-37 (non-functional)" P0DSN7 2 89884740-89885216 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;stomach 1: 15.0;urinary bladder: 20.1" "Cell type enriched" "Detected in single" 11 "Plasma cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 209 "memory B-cell: 13.6;naive B-cell: 29.1" "Lineage enriched" "Detected in single" 284 "B-cells: 29.1" "Cell line enriched" "Detected in single" 5 "HDLM-2: 2.5" HPA048721 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (2.68e-1)" 0.1 0.0 0.0 4.2 0.0 3.3 2.4 0.0 0.0 0.8 0.0 8.6 12.7 0.1 0.4 2.1 0.2 0.5 0.2 0.4 0.0 0.1 0.4 0.8 4.1 0.0 0.1 0.4 1.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 7.1 0.0 0.2 0.0 6.0 0.2 0.0 6.5 15.0 0.2 0.0 1.1 0.1 0.0 2.5 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV1D-42 ENSG00000211633 "Immunoglobulin kappa variable 1D-42 (non-functional)" A0A075B6H8 2 90190193-90190681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.7;lymphoid tissue: 25.3" "Cell type enriched" "Detected in single" 93 "Plasma cells: 9.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 5.6;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 57 "B-cells: 5.6" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 2.6" HPA048721 Approved "Immunoglobulin genes" NA NA 41000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (8.08e-6)" "unprognostic (4.83e-2)" "unprognostic (2.22e-2)" "unprognostic (2.51e-3)" "unprognostic (1.84e-1)" "unprognostic (2.10e-2)" "unprognostic (1.66e-5)" "unprognostic (1.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (1.39e-1)" 0.1 0.0 0.0 7.6 0.0 6.6 10.8 0.0 0.0 0.8 0.0 18.8 7.5 0.2 0.3 1.4 0.2 1.7 0.1 0.0 0.0 0.0 0.3 2.8 2.6 0.1 0.0 4.1 1.1 0.0 0.0 0.0 0.0 0.1 47.7 0.0 8.5 0.0 0.0 0.1 7.9 0.0 0.0 4.2 13.9 0.0 0.0 0.6 0.3 0.0 25.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.9;lymphoid tissue: 4.8;stomach 1: 3.6" "Cell type enriched" "Detected in some" 86 "Plasma cells: 695.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 152 "memory B-cell: 13.3;naive B-cell: 17.0" "Lineage enriched" "Detected in single" 171 "B-cells: 17.0" "Cell line enriched" "Detected in single" 310 "RPMI-8226: 79.1" HPA048721 Approved "Immunoglobulin genes" NA NA 380000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" 0.2 0.0 0.0 2.8 0.0 1.3 1.4 0.0 0.0 0.0 0.0 2.7 1.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 1.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 2.0 0.2 0.0 0.0 2.9 0.0 0.0 1.8 3.6 0.0 0.0 0.5 0.1 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 79.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 695.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.2;lymphoid tissue: 14.2;salivary gland: 5.6" "Cell type enriched" "Detected in some" 29 "Plasma cells: 338.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 323 "memory B-cell: 32.7;naive B-cell: 31.8" "Lineage enriched" "Detected in single" 328 "B-cells: 32.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 38.3" HPA048721 Approved "Immunoglobulin genes" NA NA 1900000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" 0.5 0.0 0.0 5.3 0.0 0.7 1.2 0.0 0.0 0.6 0.0 4.2 1.6 0.1 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.3 0.3 1.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 2.6 0.0 5.6 0.0 0.0 0.0 2.8 0.0 0.0 8.3 1.9 0.0 0.0 1.2 0.6 0.0 14.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 338.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1OR2-108 "IGKV1/OR2-108, IGKV1OR2108, IGO1" ENSG00000231292 "Immunoglobulin kappa variable 1/OR2-108 (non-functional)" 2 113406396-113406872 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.2;lymphoid tissue: 56.7" "Cell type enriched" "Detected in single" 652 "Plasma cells: 65.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "memory B-cell: 13.5;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 58 "B-cells: 13.5" "Cell line enhanced" "Detected in some" "Daudi: 6.6;HBEC3-KT: 7.2;hTEC/SVTERT24-B: 4.1;REH: 4.1" "Not detected" "Not detected" HPA048721 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.53e-6)" "unprognostic (2.73e-2)" "unprognostic (1.55e-2)" "unprognostic (3.37e-1)" "unprognostic (3.64e-3)" "unprognostic (3.57e-2)" "unprognostic (3.20e-1)" "unprognostic (5.21e-2)" "unprognostic (1.17e-1)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (9.96e-6)" "unprognostic (6.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" 0.5 1.4 0.1 23.3 0.4 11.2 16.7 0.0 0.3 4.8 5.6 38.2 21.8 0.3 0.0 6.8 0.4 5.5 0.2 0.8 0.0 0.1 1.4 6.9 14.0 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.9 22.1 0.1 15.2 0.5 0.1 4.8 13.9 0.8 0.0 12.7 16.9 0.0 0.1 3.8 1.3 0.0 56.7 21.7 0.1 0.0 2.1 0.7 0.3 0.0 0.0 0.0 0.4 0.0 2.2 0.3 1.5 3.0 1.2 6.6 0.0 0.9 1.1 0.3 0.0 7.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 4.1 2.4 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.6 0.4 0.0 1.6 4.1 0.6 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.6 0.0 1.3 0.2 0.2 0.1 1.2 0.1 0.4 0.4 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 13.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.1 0.4 0.0 0.3 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 272.7;lymphoid tissue: 474.9;urinary bladder: 935.2" "Cell type enriched" "Detected in some" 252 "Plasma cells: 5620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.1" "Lineage enriched" "Detected in single" 482 "B-cells: 48.1" "Cell line enhanced" "Detected in single" "NB-4: 1.3" "Immunoglobulin genes" NA NA 840000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" 13.7 14.6 0.1 65.8 0.1 27.4 91.8 0.0 0.6 11.5 0.4 272.7 250.8 3.2 1.1 82.0 6.6 24.1 14.7 0.2 1.0 7.8 8.6 30.0 131.7 0.6 0.1 6.3 5.6 0.2 0.9 0.2 0.9 5.4 180.6 0.0 219.3 3.3 0.3 3.3 98.5 7.9 1.1 474.9 106.8 1.2 0.2 23.7 11.1 0.0 235.6 935.2 14.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.6 0.2 1.0 0.6 0.1 0.9 1.1 0.2 0.3 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5620.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV2-40 ENSG00000273962 "Immunoglobulin kappa variable 2-40" A0A087WW87 2 89330110-89330429 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8;urinary bladder: 34.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "memory B-cell: 15.4;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 66 "B-cells: 15.4" "Cell line enhanced" "Detected in single" "Daudi: 1.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (3.31e-1)" "unprognostic (1.94e-2)" 0.4 0.1 0.0 9.3 0.0 1.1 6.7 0.0 0.1 10.2 0.0 9.7 42.8 0.9 0.0 10.5 15.5 0.1 0.1 0.0 0.0 0.3 1.4 10.9 0.9 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 1.1 7.1 0.0 5.9 2.0 0.0 0.1 6.2 0.0 0.0 17.8 19.6 0.2 0.0 1.9 1.2 0.1 6.2 34.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.7;lymphoid tissue: 25.5;urinary bladder: 15.3" "Cell type enriched" "Detected in single" 207 "Plasma cells: 165.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Cell line enriched" "Detected in single" 8 "U-937: 1.0" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.21e-4)" "unprognostic (1.78e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.09e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (4.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.74e-5)" "unprognostic (7.60e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (3.47e-1)" 0.6 0.8 0.0 4.3 0.0 2.7 6.1 0.0 0.7 0.5 0.0 16.8 19.7 0.1 0.0 1.5 0.4 3.5 0.1 1.8 0.0 0.6 0.5 1.8 6.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 7.2 0.0 9.6 0.5 0.0 0.3 7.0 0.1 0.1 25.0 5.2 0.1 0.1 1.7 0.4 0.0 25.5 15.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-26 ENSG00000211623 "Immunoglobulin kappa variable 2D-26" A0A0A0MRZ7 2 89985922-89986702 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 245 "memory B-cell: 21.8;naive B-cell: 27.1" "Lineage enriched" "Detected in single" 272 "B-cells: 27.1" "Cell line enriched" "Detected in single" 10 "U-698: 1.0" "Immunoglobulin genes" NA NA 1000000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.11e-1)" "unprognostic (6.09e-2)" 0.0 0.4 0.0 1.5 0.1 0.5 1.0 0.0 0.2 0.1 0.0 4.6 3.5 0.0 0.0 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 0.0 0.0 2.8 0.0 0.0 2.3 1.3 0.0 0.0 0.5 0.0 0.0 6.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960754 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 221.6;lymphoid tissue: 462.7;salivary gland: 259.7" "Cell type enriched" "Detected in some" 98 "Plasma cells: 4332.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 224 "memory B-cell: 3054.0;naive B-cell: 2203.9" "Lineage enriched" "Detected in all" 260 "B-cells: 3054.0" "Cell line enhanced" "Detected in some" "HDLM-2: 5.0;RPMI-8226: 2.0;SCLC-21H: 1.9;SH-SY5Y: 4.3;U-698: 4.4" "Immunoglobulin genes" NA NA 3500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.88e-3)" "unprognostic (2.68e-2)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" 9.9 4.8 0.1 162.1 0.2 23.3 35.2 0.0 1.5 7.6 0.3 203.7 221.6 8.3 1.2 113.5 14.0 26.1 4.8 0.3 0.4 11.5 13.3 40.6 166.6 0.7 0.2 2.8 1.9 0.1 0.9 0.4 0.4 11.1 65.9 0.0 259.7 19.2 0.3 1.4 143.3 8.7 0.2 462.7 186.4 5.7 0.2 40.9 37.8 0.3 192.0 157.9 8.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 5.0 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 0.0 1.9 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.6 1.3 0.0 4.4 0.0 1.1 0.0 11.7 7.8 1.2 1.2 0.5 1.3 3054.0 1.3 0.9 2.0 2203.9 0.2 0.9 2.2 1.0 1.5 1.4 1.3 248.7 0.1 0.2 0.0 1.5 0.3 0.4 0.7 0.2 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.0 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4332.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 31.5 0.0 0.1 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 222 "Plasma cells: 1314.8" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cell line enriched" "Detected in some" 6 "U-698: 51.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" 0.4 0.4 0.0 6.4 0.0 4.3 5.9 0.0 0.1 0.8 0.0 15.3 11.8 0.4 0.0 1.0 0.4 0.8 0.8 0.1 0.1 1.4 0.7 2.8 6.7 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.5 11.2 0.0 13.0 4.6 0.0 1.2 8.5 2.0 0.0 29.3 22.2 0.1 0.0 1.6 0.8 0.0 33.5 5.6 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 51.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 124.9 0.0 0.1 0.1 164.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 19.3 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1314.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852497 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 123.3" "Cell type enriched" "Detected in some" 489 "Plasma cells: 1517.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 30.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 494 "memory B-cell: 134.9;naive B-cell: 96.8" "Lineage enriched" "Detected in single" 575 "B-cells: 134.9" "Cell line enhanced" "Detected in single" "Daudi: 3.7" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-4)" "unprognostic (1.16e-2)" "unprognostic (8.37e-2)" "unprognostic (6.04e-2)" "prognostic favorable (9.78e-7)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (3.59e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" 1.7 1.4 0.0 21.0 0.0 14.8 13.5 0.0 0.1 10.0 0.0 16.6 6.9 3.0 0.0 35.6 14.4 7.7 2.0 0.0 0.0 1.0 2.9 19.5 65.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.6 21.8 0.0 32.3 21.7 0.0 0.0 31.2 1.6 0.0 44.8 38.6 0.4 0.0 26.3 5.7 0.0 123.3 34.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 134.9 0.0 0.0 0.0 96.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1517.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 34 "Plasma cells: 196.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cell line enhanced" "Detected in single" "U-266/70: 2.1" HPA047702 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" 1.3 0.7 0.3 35.9 0.2 8.9 6.4 0.0 0.1 1.7 0.0 38.6 32.2 0.8 0.0 2.4 2.1 2.7 0.5 0.0 0.1 2.1 1.3 12.4 13.0 0.1 0.3 1.5 0.5 0.0 0.1 0.0 0.1 0.7 26.6 0.0 18.8 0.3 0.0 0.1 23.6 0.7 0.2 29.9 27.7 0.2 0.0 4.2 2.3 0.0 58.5 17.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 152.5 0.0 0.0 0.1 146.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 30.2 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 196.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 415 "Plasma cells: 207.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 48.7" HPA047702 Approved "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" 0.1 0.0 0.0 5.5 0.2 1.3 0.1 0.0 0.1 0.2 0.0 4.0 4.6 0.0 0.0 1.9 0.1 1.5 0.0 0.1 0.1 0.0 0.2 0.5 1.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 2.1 0.1 0.0 0.0 4.4 0.0 0.0 3.8 4.4 0.0 0.1 0.2 0.6 0.0 4.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3OR2-268 "IGKV268, IGKV3/OR2-268, IGKV3/OR2-268A, IGKV3OR2-268A" ENSG00000233999 "Immunoglobulin kappa variable 3/OR2-268 (non-functional)" 2 87338511-87339035 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 100.4;lymphoid tissue: 85.7" "Cell type enriched" "Detected in some" 302 "Plasma cells: 2604.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 220.0;naive B-cell: 78.9" "Lineage enriched" "Detected in many" 7 "B-cells: 220.0" "Group enriched" "Detected in some" 71 "U-266/70: 183.9;U-266/84: 593.2" HPA047702 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (8.06e-4)" "unprognostic (1.69e-3)" "unprognostic (1.19e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.26e-1)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (8.68e-2)" "unprognostic (2.61e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.12e-6)" "unprognostic (2.80e-2)" "unprognostic (3.83e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-1)" 0.4 1.3 0.3 45.8 0.4 11.8 28.5 0.1 0.6 3.4 0.2 100.4 33.9 0.9 0.0 1.3 0.7 24.7 1.3 0.3 0.4 0.6 2.6 7.5 23.8 0.3 0.2 3.3 1.2 0.0 0.0 0.1 0.2 1.6 59.5 0.0 29.4 1.6 0.0 0.6 27.7 4.1 0.1 19.3 34.0 0.4 0.2 10.3 1.2 0.0 85.7 24.4 0.8 0.5 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.5 0.2 183.9 593.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 220.0 2.8 0.1 0.1 78.9 0.0 0.1 0.1 0.1 0.0 0.2 30.0 32.7 0.3 0.4 0.1 0.6 0.3 0.4 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2604.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGKV5-2 "B2, IGKV52" ENSG00000211599 "Immunoglobulin kappa variable 5-2" P06315 2 88897232-88897784 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9;lymphoid tissue: 83.1" "Cell type enriched" "Detected in some" 193 "Plasma cells: 1664.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "memory B-cell: 21.4;naive B-cell: 17.2" "Lineage enriched" "Detected in many" 21 "B-cells: 21.4" "Group enriched" "Detected in some" 19 "Daudi: 4.2;HDLM-2: 1.8;RPMI-8226: 2.3" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 4700000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.77e-3)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.37e-1)" "unprognostic (2.26e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.62e-6)" "unprognostic (2.60e-1)" "unprognostic (2.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.85e-2)" 0.9 0.0 0.0 10.3 0.0 6.4 19.6 0.0 0.0 5.3 0.0 23.3 35.9 0.8 0.0 4.0 0.9 0.9 0.1 0.0 0.0 0.9 1.0 6.3 17.3 0.0 0.0 0.4 0.4 0.5 0.0 0.0 0.0 0.6 11.1 0.0 14.9 1.9 0.0 0.5 14.3 0.2 0.0 23.5 15.3 0.0 0.0 3.0 1.0 0.0 83.1 4.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1664.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.3;lymphoid tissue: 141.0" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1715.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 28.8;naive B-cell: 9.8" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cell line enriched" "Detected in some" 6 "U-266/70: 10.5" "Immunoglobulin genes" NA NA 250000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" 2.2 0.4 0.0 41.6 0.0 12.0 37.4 0.0 0.1 3.3 0.0 97.3 38.8 1.8 0.6 8.4 1.9 5.9 0.5 0.0 0.0 2.7 2.6 11.9 64.4 0.2 0.0 2.1 0.8 0.0 0.1 0.0 0.0 1.5 79.3 0.0 43.5 9.0 0.0 0.5 38.5 5.0 0.1 63.8 36.3 0.9 0.0 10.2 3.5 0.0 141.0 37.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1715.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV6D-21 "A10, IGKV6D21" ENSG00000225523 "Immunoglobulin kappa variable 6D-21 (non-functional)" A0A0A0MT36 2 90021567-90022185 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 67.0;lymphoid tissue: 152.7;urinary bladder: 227.3" "Cell type enriched" "Detected in some" 7 "Plasma cells: 234.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 154 "memory B-cell: 14.2;naive B-cell: 16.5" "Lineage enriched" "Detected in single" 166 "B-cells: 16.5" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.95e-4)" "unprognostic (5.47e-3)" "unprognostic (2.85e-3)" "prognostic favorable (5.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (7.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" 1.1 0.4 0.0 17.2 0.0 17.2 11.8 0.0 0.1 5.4 0.0 67.0 38.8 1.6 0.0 22.1 0.8 2.7 2.1 0.2 0.0 1.6 2.4 6.3 19.8 0.6 0.0 1.1 1.1 0.0 0.0 0.0 0.1 0.8 31.8 0.0 21.1 17.3 0.0 1.2 37.8 1.0 0.0 45.3 13.4 3.4 0.0 9.1 1.4 0.0 152.7 227.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 234.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV6D-41 ENSG00000211626 "Immunoglobulin kappa variable 6D-41 (non-functional)" A0A0C4DH26 2 90069662-90070238 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.7;intestine: 3.4;lymphoid tissue: 2.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 3.0;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 49 "B-cells: 4.9" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 32000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.64e-2)" "unprognostic (4.43e-1)" 0.0 1.3 0.0 1.3 0.0 0.0 0.1 0.0 0.0 4.7 0.0 3.4 0.9 0.0 0.0 0.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.2 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 37.3;granulocytes: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cell line enriched" "Detected in many" 5 "U-266/70: 600.3" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" 132.3 163.1 2.2 1208.8 1.9 641.9 903.4 1.7 7.0 190.8 4.4 3038.0 3264.2 63.1 2.1 535.0 113.2 640.0 104.5 1.7 2.2 148.2 114.7 470.6 2372.4 3.9 1.7 135.6 69.8 8.0 13.2 1.9 2.2 71.5 2133.6 0.7 2047.0 124.0 4.9 28.8 1389.9 78.0 2.6 3332.0 2335.3 23.7 2.3 873.2 224.5 0.0 5586.9 1948.8 79.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 1.0 0.0 1.9 0.2 0.0 0.0 6.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 9.1 0.0 0.0 1.1 10.2 2.0 0.0 0.0 2.3 8.9 33.4 0.0 0.0 6.3 11.1 1.4 0.0 0.0 0.0 0.0 0.3 2.5 0.0 1.3 4.3 2.6 600.3 119.9 36.5 0.0 3.5 0.0 4.2 7.7 2.0 3.7 1.7 2.9 5729.2 3.8 2.5 6.0 5821.4 0.9 2.2 7.6 2.8 4.8 5.2 3.4 897.2 2.2 1.9 1.7 7.0 1.7 2.2 3.9 1.7 2.2 2.6 2.3 3.4 0.0 6.4 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Group enriched" "Detected in many" 40 "B-cells: 24632.2;Plasma cells: 18795.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Group enriched" "Detected in many" 190 "RPMI-8226: 62032.1;U-266/70: 102644.1;U-266/84: 83511.6" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" 386.6 782.7 7.7 3871.2 6.2 2741.4 2183.6 4.6 14.9 815.5 11.4 8217.0 9734.6 194.3 207.0 1690.0 231.5 2091.8 318.3 4.6 5.7 301.6 382.3 1442.8 5543.4 11.1 5.0 540.2 112.7 16.8 31.0 7.5 6.6 264.0 5055.4 0.7 5934.2 384.9 8.6 74.2 5290.6 306.2 6.6 7090.0 10849.9 256.0 5.4 2071.4 491.7 0.6 19988.7 6482.1 176.7 10.7 120.6 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 221.4 12.0 0.0 0.0 61.9 0.0 0.0 0.0 30.5 0.0 7.7 0.0 0.0 0.0 19.2 343.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 64.7 0.0 0.0 70.1 27.7 52.3 0.0 0.0 45.3 436.2 62032.1 0.0 0.0 46.7 45.7 5.6 43.0 17.3 0.0 17.7 57.2 11.7 0.0 38.9 23.4 78.2 102644.1 83511.6 298.8 0.7 21.9 0.7 9.9 18.6 5.6 5.8 3.0 5.7 11361.1 5.8 4.5 10.9 10650.3 3.5 4.7 118.0 5.8 8.7 303.3 6.5 2385.6 7.7 6.2 4.6 14.9 4.6 5.7 11.1 5.0 6.6 6.6 5.4 10.7 4.1 32.1 121.0 0.0 24632.2 0.0 0.3 0.0 1.2 0.0 16.1 3.0 3.9 44.3 8.1 0.0 0.0 0.3 8.0 28.0 0.0 0.0 0.0 0.0 0.1 86.3 62.5 222.4 0.0 0.0 0.3 42.5 14.8 0.0 65.6 0.0 222.8 539.9 2.1 0.0 0.0 21.5 0.0 134.5 0.0 0.0 0.0 8.5 0.0 0.0 11.4 0.0 15.5 0.0 0.0 0.0 20.6 0.0 18795.5 0.0 0.0 1.4 1.5 0.0 0.0 0.2 10.2 0.0 0.0 2.8 0.0 0.1 538.6 0.0 23.7 0.0 IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4115.7;lymphoid tissue: 8175.8;stomach 1: 4130.0;urinary bladder: 3726.3" "Group enriched" "Detected in many" 35 "B-cells: 12202.8;Plasma cells: 5357.3;T-cells: 3582.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 34 "memory B-cell: 7254.6;naive B-cell: 6119.2" "Lineage enriched" "Detected in all" 37 "B-cells: 7254.6" "Cell line enriched" "Detected in many" 15 "RPMI-8226: 10741.3" "CAB000050, CAB016533" Supported "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000050: , CAB016533: AB_629719" "prognostic favorable (2.32e-4)" "unprognostic (1.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.54e-2)" "unprognostic (8.41e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.45e-2)" "unprognostic (4.59e-2)" "unprognostic (8.77e-2)" "prognostic favorable (4.58e-4)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.04e-9)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (5.97e-2)" 156.2 550.9 2.6 2377.2 2.7 840.6 1388.6 1.4 9.1 220.4 7.1 4115.7 4046.3 115.2 33.2 508.5 88.0 707.7 63.7 1.3 2.8 178.6 171.7 1081.6 2745.8 7.2 1.4 247.8 47.6 7.0 19.0 3.2 2.0 134.0 2268.4 0.3 2264.0 177.1 5.8 20.7 2373.2 113.9 3.4 4261.5 4130.0 55.4 2.1 426.9 232.0 0.9 8175.8 3726.3 111.5 6.4 0.6 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 60.1 0.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 18.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 338.0 0.0 0.0 10.8 15.0 2.8 0.0 0.0 700.2 9.3 10741.3 0.0 0.0 16.6 25.1 4.4 20.8 0.0 0.0 4.9 0.8 11.1 0.0 6.3 7.2 5.0 88.0 103.4 36.1 1.2 5.3 0.5 6.4 9.1 3.9 6.0 2.0 27.3 7254.6 5.1 3.6 6.9 6119.2 2.6 3.3 60.7 4.3 4.6 195.3 4.7 1415.5 2.6 2.7 1.4 9.1 1.3 2.8 7.2 1.4 2.0 3.4 2.1 6.4 2.0 22.4 97.3 0.0 12202.8 0.0 0.7 0.0 0.0 0.0 5.4 0.5 15.3 8.6 3.7 0.0 0.0 0.2 8.8 5.0 0.0 0.0 0.0 0.0 0.1 7.4 12.2 54.8 0.0 0.0 0.0 22.1 5.6 0.1 47.9 0.0 195.9 127.7 0.2 0.0 0.0 3.5 0.0 23.1 0.0 0.0 0.0 5.6 0.0 0.0 2.0 0.0 2.1 0.0 0.0 0.0 3.1 0.0 5357.3 0.2 0.0 1.1 2.2 0.0 0.0 0.0 4.2 0.0 0.0 0.8 0.0 0.1 3582.0 0.0 6.3 0.9 IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 10 "B-cells: 109.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cell line enriched" "Detected in some" 913 "Karpas-707: 122629.0" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" 5.6 4.7 0.0 27.9 0.0 19.9 15.6 0.0 0.4 5.1 0.0 54.1 88.1 4.4 0.5 8.4 4.3 10.7 1.4 0.0 0.5 2.3 3.5 8.3 40.8 0.3 0.0 2.5 1.7 0.1 0.2 0.0 0.2 4.4 23.1 0.0 70.1 0.6 0.1 0.2 23.1 0.9 0.0 107.7 113.1 0.8 0.1 20.0 5.7 0.0 104.2 19.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 112.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122629.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.7 3.0 0.6 111.2 0.0 47.3 0.3 0.1 0.0 0.0 0.1 0.0 128.8 0.0 0.0 0.1 133.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 25.5 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ6 ENSG00000211682 "Immunoglobulin lambda joining 6" 22 22918132-22918201 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "intestine: 6.6;lymphoid tissue: 7.9;urinary bladder: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "colorectal cancer: 1.2;endometrial cancer: 1.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "memory B-cell: 31.6;naive B-cell: 38.3" "Lineage enriched" "Detected in single" 52 "B-cells: 38.3" "Group enriched" "Detected in some" 8 "Daudi: 14.5;U-698: 4.3" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" 0.0 0.0 0.2 7.2 0.2 0.0 0.4 0.0 0.3 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 1.0 0.0 7.9 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 5.3 1.0 0.0 0.4 0.0 0.0 0.0 2.8 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.9 0.2 0.2 0.0 0.3 0.1 0.8 0.3 0.4 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ7 ENSG00000211684 "Immunoglobulin lambda joining 7" 22 22921390-22921435 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 12.3;lymphoid tissue: 19.0;stomach 1: 17.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.0;endometrial cancer: 1.5" "Region enhanced" "Detected in some" "cerebral cortex: 3.4" "Group enriched" "Detected in some" 222 "memory B-cell: 314.0;naive B-cell: 370.8" "Lineage enriched" "Detected in many" 240 "B-cells: 370.8" "Cell line enriched" "Detected in single" 21 "U-266/70: 2.0" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" 0.7 4.1 0.1 14.5 0.1 1.1 0.0 0.3 3.4 0.0 0.0 6.1 12.3 0.0 0.0 2.1 0.0 3.3 0.0 0.2 0.9 0.0 0.0 2.0 3.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.8 1.9 0.0 5.9 0.0 0.0 0.0 5.4 0.0 0.0 3.8 17.5 1.8 0.1 0.3 0.0 0.0 19.0 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.6 314.0 0.0 0.0 0.0 370.8 0.0 0.0 0.0 0.0 1.5 0.2 0.0 27.6 0.1 0.1 0.3 3.4 0.2 0.9 1.2 0.4 0.7 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLL1 "14.1, CD179B, IGL5, IGLL, IGVPB" ENSG00000128322 "Immunoglobulin lambda like polypeptide 1" P15814 22 23573125-23580302 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 70.0;testis: 25.2" "Group enriched" "Detected in some" 6 "Early spermatids: 78.0;Late spermatids: 140.7;Melanocytes: 119.2" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.5;lung cancer: 0.5;stomach cancer: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 12.0;naive B-cell: 14.8" "Lineage enriched" "Detected in many" 11 "B-cells: 14.8" "Cell line enriched" "Detected in some" 32 "REH: 787.7" "HPA051134, HPA071406" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 48000000000 "Cluster 24: B-cells - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA051134: AB_2681356, HPA071406: AB_2686393" "unprognostic (6.21e-2)" "unprognostic (5.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.91e-6)" "unprognostic (1.08e-1)" "unprognostic (5.27e-2)" "unprognostic (6.17e-3)" "unprognostic (5.89e-2)" "unprognostic (9.07e-2)" "unprognostic (1.99e-4)" "unprognostic (2.35e-2)" "unprognostic (5.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.3 0.3 0.3 70.0 0.0 0.3 0.4 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.1 1.4 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.2 25.2 0.2 10.1 0.0 0.0 1.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 14.3 2.6 0.0 0.0 0.0 787.7 0.3 17.3 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.1 6.2 0.0 0.0 0.3 0.3 0.0 0.6 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.8 0.3 0.3 0.3 0.4 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.4 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.9 0.0 78.0 0.2 0.3 0.3 0.0 10.5 0.3 0.0 0.4 0.6 0.0 0.5 0.0 0.2 0.7 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 140.7 1.2 0.4 119.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.0 6.2 0.0 0.0 0.0 1.5 0.3 17.1 0.6 0.0 0.3 0.0 17.9 0.1 0.0 0.2 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV1-50 ENSG00000211645 "Immunoglobulin lambda variable 1-50 (non-functional)" A0A075B6I6 22 22327300-22327814 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.4;lymphoid tissue: 14.7;stomach 1: 20.4" "Cell type enriched" "Detected in single" 2575 "Plasma cells: 1545.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 21 "memory B-cell: 11.0;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 33 "B-cells: 11.0" "Cell line enhanced" "Detected in single" "HEK 293: 1.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-4)" "unprognostic (8.01e-2)" "unprognostic (1.28e-3)" "unprognostic (6.91e-2)" "unprognostic (2.10e-1)" "prognostic favorable (7.08e-4)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (7.38e-2)" "unprognostic (1.58e-4)" "unprognostic (4.89e-3)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" 0.5 0.5 0.1 6.1 0.1 3.3 6.7 1.7 1.9 0.5 0.0 5.4 16.4 0.6 1.2 2.4 0.5 0.8 0.0 0.6 0.0 0.2 0.2 4.4 1.9 0.6 0.0 0.9 0.1 0.1 0.1 0.0 0.6 0.3 4.5 0.7 4.6 0.3 0.4 0.0 9.4 0.2 0.0 3.9 20.4 0.4 0.0 0.6 0.2 0.0 14.7 9.3 0.1 1.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.3 0.5 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.1 0.0 0.3 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 1.7 1.9 0.6 0.0 0.6 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1545.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 17 "Plasma cells: 358.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cell line enhanced" "Detected in single" "TIME: 2.3" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" 3.6 1.9 0.1 96.4 0.3 33.8 121.9 0.1 2.2 2.0 0.8 324.6 294.8 1.5 0.0 22.5 24.3 21.9 12.0 0.1 0.3 2.5 7.0 22.3 64.7 1.4 0.1 2.6 11.6 0.0 0.4 0.4 0.2 6.4 155.1 0.0 253.6 2.3 0.1 1.0 138.9 12.7 0.2 155.3 194.5 0.4 0.1 22.9 2.5 0.0 329.7 21.8 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 60.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 0.3 0.1 2.2 0.1 0.3 1.4 0.1 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV11-55 ENSG00000211641 "Immunoglobulin lambda variable 11-55 (non-functional)" A0A075B6I3 22 22201663-22202161 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Cell type enhanced" "Detected in some" "Late spermatids: 3.5;Plasma cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Daudi: 8.6;U-698: 2.7" "Immunoglobulin genes" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.22e-1)" "unprognostic (6.16e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 210 "Plasma cells: 2488.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Group enriched" "Detected in some" 7 "RPMI-8226: 13.4;U-266/70: 22.3;U-266/84: 7.2" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" 3.4 0.3 0.0 73.0 0.0 23.7 67.1 0.0 0.3 6.7 0.1 271.5 262.0 4.2 0.0 39.6 10.8 36.3 12.5 0.0 0.0 2.0 2.8 12.6 37.6 0.1 0.0 4.1 1.1 2.1 0.2 0.1 0.4 1.7 138.6 0.0 64.3 4.9 0.1 0.3 150.2 6.5 0.0 95.8 72.5 0.5 0.0 22.1 2.8 0.0 224.4 18.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 13.4 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.3 7.2 0.1 0.1 0.1 0.0 0.2 1.8 0.0 1.6 0.0 0.8 321.2 0.3 1.3 0.1 126.9 0.7 0.6 0.5 5.0 0.1 0.2 0.1 69.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2488.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-33 ENSG00000211656 "Immunoglobulin lambda variable 2-33 (non-functional)" A0A075B6J2 22 22588155-22588688 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.3;lymphoid tissue: 2.7;salivary gland: 2.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 2.9;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 30 "B-cells: 2.9" "Group enriched" "Detected in some" 9 "RPMI-8226: 1.5;U-266/70: 5.1;U-266/84: 3.4" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "unprognostic (1.29e-2)" "unprognostic (1.79e-3)" "unprognostic (2.13e-1)" "unprognostic (4.30e-1)" "unprognostic (2.64e-3)" "unprognostic (2.47e-2)" "unprognostic (2.06e-1)" "unprognostic (6.68e-2)" 0.0 0.1 0.0 1.5 0.0 1.3 0.4 0.0 0.0 0.0 0.0 2.2 4.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.6 0.0 0.0 0.0 2.3 0.2 0.0 1.5 1.5 0.0 0.0 0.1 0.0 0.0 2.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 52 "Plasma cells: 1090.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HL-60: 1.0;RH-30: 1.6" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" 33.3 112.9 0.5 144.0 0.4 65.5 111.1 0.1 3.3 41.3 0.6 308.0 176.3 7.6 4.5 56.3 7.9 43.5 20.5 0.1 0.2 12.2 20.8 48.0 230.5 1.8 0.2 14.6 10.8 0.9 0.8 0.4 0.6 11.0 317.0 0.0 139.7 10.8 0.2 8.1 94.9 5.8 0.1 217.1 288.7 97.4 0.2 25.9 8.6 0.0 707.7 140.2 7.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.2 0.0 0.2 548.7 0.1 0.2 0.2 315.0 0.0 0.2 0.3 0.1 0.1 0.3 0.1 43.2 0.5 0.4 0.1 3.3 0.1 0.2 1.8 0.2 0.6 0.1 0.2 0.2 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 7.1 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1090.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.2 0.0 IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.2;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.7;NK-cell: 5.6" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.6;T-cells: 4.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" 0.8 1.2 0.0 3.9 0.0 2.7 1.9 0.0 0.3 0.3 0.1 7.3 5.5 0.5 0.0 1.0 0.6 3.3 0.0 0.0 0.0 0.1 0.5 2.7 15.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 5.1 1.7 0.0 0.2 2.7 0.1 0.0 4.6 8.2 0.9 0.0 3.9 0.2 0.0 30.1 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 1.1 9.2 1.0 4.0 0.0 6.7 0.0 0.2 0.0 5.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 80.3;urinary bladder: 42.9" "Group enriched" "Detected in some" 49 "B-cells: 6.2;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 393 "memory B-cell: 107.2;naive B-cell: 121.2" "Lineage enriched" "Detected in single" 417 "B-cells: 121.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 350000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" 1.5 0.0 0.0 6.9 0.0 6.3 4.9 0.0 0.0 0.7 0.0 10.7 9.9 0.2 0.0 2.5 1.9 1.2 0.6 0.0 0.0 0.7 1.3 4.7 13.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.6 10.8 0.0 10.8 0.0 0.0 0.1 5.2 0.6 0.0 12.8 13.0 0.3 0.0 3.5 0.2 0.0 80.3 42.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 107.2 0.0 0.1 0.1 121.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-22 ENSG00000211661 "Immunoglobulin lambda variable 3-22" A0A075B6J6 22 22704265-22704822 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.6;lymphoid tissue: 9.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 72 "memory B-cell: 6.6;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 1100000000 "Cluster 37: B-cells - Transcription" "Cluster 63: T-cells - Adaptive immune response" "unprognostic (2.00e-1)" "unprognostic (9.93e-3)" "unprognostic (3.73e-1)" 0.0 0.7 0.0 1.0 0.0 1.5 2.6 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.8 0.3 0.0 0.0 1.4 0.0 0.0 1.4 0.8 0.3 0.0 9.5 0.0 0.0 5.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV3-32 ENSG00000211657 "Immunoglobulin lambda variable 3-32 (non-functional)" A0A0A0MS00 22 22594528-22595056 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 14: B-cells - Humoral immune response" "unprognostic (4.68e-2)" "unprognostic (1.31e-1)" "unprognostic (7.93e-2)" 0.0 0.0 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 313.9;stomach 1: 117.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 13.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "memory B-cell: 64.7;naive B-cell: 168.7" "Lineage enriched" "Detected in many" 74 "B-cells: 168.7" "Cell line enriched" "Detected in some" 5 "U-266/70: 41.3" HPA003285 Approved "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" 1.8 23.5 0.1 84.6 0.0 27.8 14.9 0.0 0.1 7.3 0.1 87.1 58.7 2.0 0.0 20.8 1.8 18.6 7.6 0.0 0.0 3.2 6.2 17.1 139.8 0.7 0.0 3.9 2.4 0.2 0.1 0.0 0.1 1.4 64.0 0.0 46.2 3.1 0.1 1.5 60.3 5.2 0.0 64.6 117.3 1.6 0.1 35.0 3.8 0.0 313.9 72.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.1 0.3 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 0.3 0.0 41.3 5.8 0.7 0.0 3.9 0.0 0.0 0.1 0.0 1.2 0.0 2.2 64.7 1.3 1.4 0.0 168.7 0.4 1.8 0.1 0.5 0.1 0.0 0.1 6.5 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 15.7;stomach 1: 28.9" "Cell type enriched" "Detected in some" 23 "Plasma cells: 50.3" "Cancer enhanced" "Detected in many" "lung cancer: 4.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 11.7;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 118 "B-cells: 11.7" "Cell line enriched" "Detected in single" 5 "Daudi: 1.3" "Immunoglobulin genes" NA NA 1600000 "Cluster 37: B-cells - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.22e-2)" "unprognostic (5.51e-3)" "unprognostic (2.71e-1)" "unprognostic (4.37e-4)" "unprognostic (1.87e-1)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" 0.2 0.0 0.0 2.1 0.0 1.4 1.6 0.0 0.0 0.3 0.0 5.1 4.5 0.3 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.1 0.1 1.0 10.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 3.3 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 5.3 28.9 0.2 0.0 1.4 0.4 0.0 15.7 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 152 "Plasma cells: 1125.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 4 "Daudi: 7.8;HEL: 13.3;U-698: 3.9" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" 1.8 1.9 0.0 32.9 0.0 18.1 36.6 0.0 0.2 3.3 0.1 70.7 193.1 1.5 0.0 12.3 1.9 3.4 11.4 0.0 0.0 3.1 3.9 43.5 116.3 0.0 0.0 4.6 1.1 0.4 0.2 0.2 0.1 1.1 73.3 0.0 37.9 0.8 0.1 0.1 86.8 2.1 0.0 80.3 37.7 1.7 0.0 18.3 1.7 0.0 112.0 185.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 3.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.4 0.1 0.0 0.0 48.9 0.0 0.0 0.8 0.0 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1125.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV5-37 ENSG00000211654 "Immunoglobulin lambda variable 5-37" A0A075B6J1 22 22427540-22428035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 24.7;intestine: 10.5;lymphoid tissue: 41.5;salivary gland: 11.5;stomach 1: 16.5" "Group enriched" "Detected in some" 4 "B-cells: 2.5;Late spermatids: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "memory B-cell: 6.1;naive B-cell: 7.0" "Lineage enriched" "Detected in single" 58 "B-cells: 7.0" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 14000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (4.69e-4)" "unprognostic (2.44e-2)" "unprognostic (5.68e-3)" "unprognostic (4.26e-1)" "prognostic favorable (4.71e-4)" "unprognostic (4.97e-2)" "unprognostic (3.56e-2)" "unprognostic (3.15e-1)" "unprognostic (5.34e-6)" "unprognostic (1.66e-1)" "unprognostic (4.32e-1)" "unprognostic (1.25e-1)" 0.7 0.0 0.0 9.5 0.0 1.0 3.2 0.0 0.0 1.8 0.0 10.5 10.1 0.2 0.0 4.2 0.9 24.7 1.1 0.0 0.0 0.9 0.7 3.6 4.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.6 8.0 0.1 11.5 0.0 0.0 0.0 8.8 0.2 0.0 22.7 16.5 1.2 0.0 8.4 0.6 0.0 41.5 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 40.5;intestine: 43.5;lymphoid tissue: 97.5;salivary gland: 49.0" "Cell type enriched" "Detected in some" 116 "Plasma cells: 6697.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 160000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" 2.2 0.3 0.0 0.0 0.0 0.4 5.5 0.0 0.4 3.3 0.0 43.5 0.0 0.7 0.0 40.5 2.0 0.0 0.2 0.0 0.0 2.5 3.1 9.6 0.0 0.1 0.0 0.6 0.6 0.0 0.2 0.0 0.1 1.1 0.2 0.0 49.0 0.0 0.1 0.7 42.1 0.0 0.0 97.5 14.1 0.4 0.0 0.0 4.0 0.0 1.4 14.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 57.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6697.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 IGLV5-48 ENSG00000211647 "Immunoglobulin lambda variable 5-48 (non-functional)" A0A075B6I7 22 22352940-22353433 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 5.5;urinary bladder: 2.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 19.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 5.4;naive B-cell: 6.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.76e-3)" "unprognostic (1.91e-2)" "unprognostic (9.43e-2)" "unprognostic (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-2)" "unprognostic (2.97e-1)" 0.0 0.0 0.0 0.9 0.0 1.3 0.9 0.0 0.6 0.4 0.0 3.3 3.3 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.1 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 1.3 0.2 0.0 5.5 0.7 0.0 0.0 2.5 0.1 0.0 5.3 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 57 "Plasma cells: 1304.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Cell line enhanced" "Detected in some" "Daudi: 1.9;RPMI-8226: 1.4;U-698: 1.5" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" 8.0 0.8 0.0 31.2 0.1 15.8 45.7 0.0 0.5 4.9 0.0 161.9 132.8 3.6 0.5 7.9 3.3 22.1 3.5 0.0 0.1 3.1 4.2 13.0 59.0 0.0 0.0 4.1 2.2 0.0 1.0 0.2 0.1 2.3 129.3 0.0 72.5 4.7 0.1 0.5 57.1 17.7 0.0 168.6 115.9 0.5 0.0 31.3 6.4 0.7 238.7 31.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 132.0 0.0 0.0 0.0 54.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.2 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1304.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.2 0.0 IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 180 "Plasma cells: 6758.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cell line enhanced" "Detected in some" "Daudi: 8.0;RPMI-8226: 2.8;U-698: 6.6" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" 15.1 3.8 0.0 59.8 0.3 44.2 171.7 0.1 0.9 4.1 0.1 400.6 162.4 4.4 0.0 43.7 3.0 56.0 5.2 0.0 1.6 5.7 7.7 44.9 82.2 0.4 0.0 9.0 6.2 0.1 0.8 0.1 0.2 2.5 298.6 0.0 107.2 5.2 0.5 0.8 133.1 12.1 0.1 248.1 250.7 0.7 0.2 57.3 8.7 0.0 459.1 444.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.3 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 183.6 0.1 0.0 0.1 82.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 15.2 0.0 0.3 0.1 0.9 0.0 1.6 0.4 0.0 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6758.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 805.8;lymphoid tissue: 984.2" "Cell type enriched" "Detected in some" 4 "B-cells: 25.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Group enriched" "Detected in some" 630 "memory B-cell: 257.8;naive B-cell: 529.3" "Lineage enriched" "Detected in single" 848 "B-cells: 529.3" "Cell line enhanced" "Detected in some" "Daudi: 2.2;RPMI-8226: 3.6;SH-SY5Y: 1.8;U-266/70: 6.6" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 620000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.07e-3)" "unprognostic (2.73e-2)" "prognostic favorable (3.84e-4)" "unprognostic (1.07e-2)" "unprognostic (5.24e-2)" "unprognostic (1.04e-3)" "unprognostic (1.65e-1)" "unprognostic (1.75e-3)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" 9.4 4.9 0.1 125.5 0.2 63.9 78.3 0.1 3.5 43.5 1.0 201.1 805.8 22.7 0.8 10.6 5.6 46.4 11.7 0.1 0.2 5.3 13.7 82.2 257.2 0.2 0.1 9.2 13.4 1.3 0.8 0.0 0.7 10.5 191.0 0.0 108.6 1.0 0.2 4.0 161.6 13.0 0.8 275.7 179.2 3.3 0.1 16.5 11.5 0.0 984.2 247.8 3.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.2 3.6 0.0 0.0 1.0 1.8 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.3 6.6 1.0 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.2 0.1 257.8 0.3 0.0 0.4 529.3 0.0 0.0 0.2 0.1 0.4 0.1 0.2 32.7 0.1 0.2 0.1 3.5 0.1 0.2 0.2 0.1 0.7 0.8 0.1 1.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 20 "Plasma cells: 46.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" 2.4 125.5 0.0 14.7 0.0 9.8 6.1 0.1 0.5 3.3 0.0 33.6 36.5 2.2 0.0 6.0 3.2 1.1 1.2 0.2 0.0 1.2 4.4 43.8 118.0 0.2 0.0 3.3 1.4 0.0 0.1 0.1 0.2 0.9 15.1 0.0 29.7 1.0 0.1 0.1 28.2 0.4 0.0 65.9 46.3 2.0 0.0 14.0 3.4 0.1 97.9 39.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.3 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.1 0.5 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 73.4;pituitary gland: 167.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Astrocytes: 3.9;Bipolar cells: 14.0;Breast glandular cells: 5.0;Horizontal cells: 3.3;Melanocytes: 3.6;Skeletal myocytes: 7.2" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 65.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 47.6;SH-SY5Y: 31.2" "Region enhanced" "Detected in all" "hypothalamus: 144.0" "Low region specificity" "Detected in all" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA012732: AB_2732404, HPA035582: AB_2674687" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (4.25e-8)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (8.03e-3)" "unprognostic (9.36e-2)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (5.13e-2)" 1.9 12.5 9.7 0.8 10.0 0.1 2.8 9.7 9.7 3.3 4.8 0.9 0.4 1.2 2.4 1.6 2.5 1.2 12.1 7.5 73.4 0.7 1.5 0.3 0.4 10.0 21.6 1.1 2.6 0.8 167.8 0.7 24.0 4.0 0.4 6.4 2.4 5.7 2.0 1.4 0.6 3.1 7.4 0.3 1.0 12.2 32.4 0.6 4.5 5.1 0.9 0.4 0.9 8.4 0.4 0.6 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.0 0.0 0.0 0.1 1.8 0.0 0.0 6.0 0.4 0.0 3.0 47.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 4.1 2.8 0.0 0.0 0.0 0.1 0.1 0.2 3.4 31.2 0.0 0.2 0.0 4.1 0.6 0.0 0.0 0.5 0.8 0.0 4.1 1.2 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 10.0 9.7 9.7 7.5 73.4 10.0 21.6 24.0 7.4 32.4 8.4 0.2 3.2 0.6 3.9 0.2 0.0 0.5 0.0 1.2 14.0 5.0 1.7 2.3 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.3 1.5 0.0 0.1 0.0 0.7 0.7 0.3 0.0 3.3 0.4 0.0 0.0 0.0 0.8 1.1 0.0 0.2 3.6 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.7 0.0 7.2 0.3 0.1 0.4 0.0 0.4 0.3 0.1 0.0 0.0 0.3 IHO1 "CCDC36, CT74, FLJ25320, LELA1" ENSG00000173421 "Interactor of HORMAD1 1" Q8IYA8 3 49198428-49258106 "Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 7.5;testis: 26.5" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Cardiomyocytes: 1.4;Fibroblasts: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.9;hTEC/SVTERT24-B: 9.2;LHCN-M2: 4.0;NTERA-2: 2.5;U-2197: 5.1;WM-115: 2.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA045690, HPA069534" Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA045690: AB_10964634, HPA069534: AB_2686146" "unprognostic (1.54e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-2)" "unprognostic (1.49e-2)" "unprognostic (9.94e-3)" "unprognostic (2.62e-1)" "unprognostic (1.38e-1)" "unprognostic (1.36e-2)" "unprognostic (5.51e-4)" "unprognostic (3.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.59e-2)" "unprognostic (6.33e-2)" 3.2 1.4 0.2 0.3 0.2 0.2 1.8 0.9 0.5 1.3 7.5 1.1 0.2 1.2 0.4 0.4 1.3 0.7 1.1 0.4 0.0 0.3 0.1 0.5 0.3 0.1 0.3 3.8 0.2 0.1 0.2 0.9 0.1 0.4 0.1 0.7 0.3 0.5 0.9 0.6 0.4 1.0 0.1 0.5 0.3 26.5 0.5 0.1 1.0 0.8 0.1 0.8 0.6 0.1 0.0 0.1 0.0 0.0 1.9 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.1 1.7 0.0 9.2 0.0 0.0 1.2 0.0 0.0 0.1 4.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 5.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.5 0.4 0.0 0.1 0.3 0.1 0.1 0.5 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 64.0;Early spermatids: 19.3;Excitatory neurons: 17.5;Late spermatids: 35.0;Muller glia cells: 20.2;Oligodendrocyte precursor cells: 20.6" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" 8.4 5.7 71.9 1.6 79.7 0.4 6.4 68.7 58.7 15.2 21.6 5.6 9.4 6.5 1.1 8.9 5.0 5.1 11.6 66.0 70.9 2.6 0.8 6.2 1.2 79.1 62.2 9.3 5.9 0.4 8.9 1.6 61.8 5.5 0.5 10.6 4.3 1.6 131.1 5.4 5.7 1.2 79.6 0.9 4.4 3.9 68.2 0.2 7.6 24.5 0.3 5.4 9.9 79.8 16.5 2.2 3.5 7.6 8.1 4.6 18.3 4.5 1.1 0.4 0.8 7.6 8.7 11.0 0.8 0.4 5.3 8.5 1.5 0.1 0.2 4.0 12.2 0.8 0.7 9.1 1.0 12.2 2.4 6.3 0.1 0.6 0.0 6.9 5.0 15.3 4.5 0.0 3.0 15.9 13.6 10.0 10.7 19.2 2.6 17.8 8.6 1.3 0.2 14.1 20.7 6.7 2.6 3.8 18.3 6.1 9.6 10.4 27.1 1.7 3.0 1.4 5.7 2.0 1.7 2.9 4.0 5.7 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.9 79.7 68.7 58.7 66.0 70.9 79.1 62.2 61.8 79.6 68.2 79.8 0.7 0.0 0.0 64.0 0.2 2.4 0.3 0.0 1.2 1.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 1.1 0.3 0.7 0.0 0.1 19.3 0.2 1.6 0.6 0.0 0.4 17.5 0.2 7.4 7.6 0.0 0.7 0.0 0.9 1.4 0.0 0.4 0.0 12.2 0.1 0.0 0.3 1.9 35.0 11.5 0.2 8.8 2.8 0.0 20.2 0.0 20.6 12.5 0.2 0.1 1.2 0.0 0.5 0.2 0.2 0.0 4.9 0.0 9.4 2.0 8.6 0.6 0.0 2.0 1.1 0.3 0.1 0.3 0.2 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IL1RAPL2 "IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1" ENSG00000189108 "Interleukin 1 receptor accessory protein like 2" Q9NP60 X 104566199-105767829 "Enzymes, Predicted membrane proteins" "Hydrolase, Receptor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;parathyroid gland: 1.0" "Group enriched" "Detected in some" 22 "Excitatory neurons: 191.3;Inhibitory neurons: 117.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1.4;hTERT-HME1: 5.6;NTERA-2: 1.0;RT4: 2.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.62e-1)" "unprognostic (1.50e-1)" "unprognostic (1.66e-2)" "unprognostic (3.09e-1)" "unprognostic (1.48e-4)" "unprognostic (9.32e-3)" "unprognostic (1.67e-1)" "unprognostic (6.80e-5)" "unprognostic (1.78e-2)" "unprognostic (2.79e-3)" "unprognostic (5.91e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.84e-2)" 0.0 1.4 0.1 0.0 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.9 0.0 0.0 0.0 0.4 0.2 0.0 1.0 0.0 0.4 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.4 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.4 0.1 0.0 0.5 0.0 0.1 0.0 0.0 6.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 2.4 0.1 0.2 0.1 0.0 0.0 191.3 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 117.4 0.0 0.0 0.0 0.0 0.2 5.9 0.0 0.0 2.8 0.0 0.0 0.0 3.0 4.6 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 2.6 0.0 1.4 0.0 0.4 IL21R CD360 ENSG00000103522 "Interleukin 21 receptor" Q9HBE5 16 27402174-27452042 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 7.6;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "B-cells: 15.5;dendritic cells: 21.8;Langerhans cells: 11.4;NK-cells: 23.7;Plasma cells: 13.4;T-cells: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 25.9;HDLM-2: 110.8;Karpas-707: 49.3;RH-30: 37.2;RPMI-8226: 63.0;U-266/70: 24.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042296 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA042296: AB_10806236" "unprognostic (2.91e-2)" "unprognostic (2.65e-3)" "unprognostic (6.64e-4)" "unprognostic (1.58e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.29e-4)" "unprognostic (8.33e-2)" "unprognostic (2.06e-1)" "unprognostic (8.50e-6)" "unprognostic (2.26e-2)" "unprognostic (1.13e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-10)" "unprognostic (8.79e-2)" "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.58e-2)" 0.5 0.4 1.4 11.9 1.0 7.6 0.2 1.1 2.6 0.2 0.9 0.8 0.6 0.3 0.2 0.3 0.2 1.1 0.7 0.9 2.3 0.9 0.4 2.9 24.7 2.1 2.3 0.2 0.3 0.0 0.5 0.8 3.3 0.4 0.9 1.1 0.6 0.1 0.3 0.8 2.1 0.7 1.2 5.5 1.5 1.1 1.2 14.4 0.6 0.0 18.8 2.2 0.2 1.6 0.1 0.2 0.3 0.2 0.0 1.3 0.8 0.8 0.1 0.1 2.2 0.2 0.2 25.9 0.2 2.1 1.4 0.1 0.0 0.1 0.1 110.8 0.1 5.4 0.2 0.7 3.4 0.2 1.5 3.8 0.0 6.8 0.1 0.7 0.0 0.6 0.3 49.3 3.8 0.2 0.1 0.5 0.9 0.1 0.0 0.4 37.2 63.0 0.0 0.1 0.2 0.2 0.1 0.1 2.7 0.2 0.1 1.3 2.8 1.9 0.7 0.6 0.2 24.7 9.4 5.9 5.2 1.4 0.2 0.5 0.4 0.1 13.4 8.3 4.9 1.8 8.6 14.2 2.3 14.2 9.2 9.3 0.9 9.5 27.0 1.1 10.8 7.3 1.4 1.0 1.1 2.6 0.9 2.3 2.1 2.3 3.3 1.2 1.2 1.6 0.2 0.0 1.3 0.0 15.5 0.4 0.1 0.0 0.0 2.0 0.2 0.1 1.9 0.0 0.0 0.0 4.2 0.1 21.8 0.1 0.0 0.0 6.5 0.1 0.2 0.9 0.0 0.0 0.4 0.0 0.1 0.3 1.5 0.2 0.0 0.0 1.1 0.2 8.2 0.0 0.5 0.0 0.0 5.0 11.4 5.7 0.0 3.6 1.8 2.8 1.8 0.2 23.7 0.5 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.2 0.0 0.5 0.0 0.8 0.8 0.2 0.0 0.0 0.9 0.1 25.1 0.1 0.1 0.1 IL23R IL-23R ENSG00000162594 "Interleukin 23 receptor" Q5VWK5 1 67138907-67259979 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.6;testis: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 11.1;Enteroendocrine cells: 3.0;Late spermatids: 6.0;T-cells: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 21.7" "Lineage enriched" "Detected in single" 29 "T-cells: 21.7" "Cell line enhanced" "Detected in some" "HL-60: 2.4;HMC-1: 9.1;K-562: 3.6;U-2197: 13.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056427 Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA056427: AB_2683129" "unprognostic (4.01e-3)" "unprognostic (8.04e-2)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.96e-1)" "unprognostic (3.16e-3)" "unprognostic (1.57e-1)" "unprognostic (2.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.88e-1)" "unprognostic (1.66e-2)" "unprognostic (1.40e-1)" "unprognostic (8.64e-5)" "unprognostic (1.43e-1)" "unprognostic (3.02e-1)" "unprognostic (2.73e-2)" "unprognostic (6.41e-3)" 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.9 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.4 1.5 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 2.4 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 13.8 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 21.7 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 11.1 0.2 0.1 0.1 3.0 0.0 0.3 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.7 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.2 6.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.1 0.2 0.0 0.2 0.7 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.3 0.0 4.2 0.0 0.4 0.2 IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Cell type enhanced" "Detected in many" "dendritic cells: 130.1;Extravillous trophoblasts: 85.5;NK-cells: 388.3;T-cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cell line enriched" "Detected in some" 8 "HDLM-2: 525.8" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" 3.2 1.3 2.0 22.4 1.6 36.8 1.9 0.8 2.3 2.2 1.5 5.1 5.5 7.6 2.9 3.5 2.9 6.8 1.9 2.2 1.0 1.0 8.5 12.4 35.7 2.4 2.2 1.6 0.8 0.4 0.6 36.3 1.9 2.3 5.2 0.0 4.3 3.2 0.7 8.9 8.3 2.5 1.7 50.2 6.4 1.5 3.3 14.9 1.8 0.7 24.0 8.0 1.0 1.8 0.4 0.0 1.0 0.0 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 525.8 0.6 1.0 0.0 0.1 0.0 0.0 24.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.7 0.1 4.2 3.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.6 2.3 0.0 0.9 0.0 0.0 13.2 0.0 0.6 36.2 66.0 0.1 0.4 0.4 0.5 5.4 0.1 0.5 50.8 0.6 27.4 0.4 11.4 28.6 0.1 1.9 3.6 15.0 1.2 186.4 0.5 0.3 24.4 37.3 2.0 1.6 0.8 2.3 2.2 1.0 2.4 2.2 1.9 1.7 3.3 1.8 1.5 3.2 6.8 0.0 3.6 3.2 0.7 0.1 5.7 0.0 1.0 0.8 1.7 0.0 0.6 1.8 0.0 0.6 130.1 0.2 0.0 0.3 2.2 0.5 1.2 1.0 0.0 16.8 0.1 0.2 85.5 1.4 5.6 1.2 10.1 0.1 7.1 1.8 2.3 0.0 0.1 0.1 0.0 5.3 1.7 1.6 0.3 3.7 5.4 0.0 2.0 0.0 388.3 0.0 0.1 0.0 0.0 0.0 18.6 0.2 0.1 0.2 0.7 0.0 0.0 0.2 0.9 0.0 0.3 0.5 1.6 1.2 103.6 0.0 0.3 0.1 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 IL4I1 FIG1 ENSG00000104951 "Interleukin 4 induced 1" Q96RQ9 19 49889654-49929539 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 18.3;testis: 26.8" "Group enriched" "Detected in many" 5 "Langerhans cells: 295.1;monocytes: 682.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 35.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 103.4" "Group enriched" "Detected in many" 6 "monocytes: 36.8;T-cells: 103.4" "Cell line enhanced" "Detected in many" "EFO-21: 34.3;HDLM-2: 62.4;Karpas-707: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045598 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cytosol" "HPA045598: AB_10969138" "unprognostic (6.23e-2)" "unprognostic (1.32e-2)" "unprognostic (8.39e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.61e-2)" "unprognostic (3.74e-3)" "unprognostic (7.03e-2)" "unprognostic (2.52e-2)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.23e-10)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (6.44e-2)" "unprognostic (2.11e-3)" 1.6 0.6 0.4 18.3 0.6 4.2 0.9 0.8 0.6 1.1 0.7 1.7 4.1 1.6 0.2 0.6 3.9 2.0 0.5 0.6 0.5 4.8 1.2 2.4 9.3 1.7 0.9 0.4 0.7 0.2 0.6 1.9 1.8 0.8 1.4 0.1 0.9 0.5 0.3 1.3 2.7 1.5 1.0 4.1 3.1 26.8 1.2 3.4 0.5 0.2 6.7 4.5 0.5 2.3 1.0 1.2 0.8 0.7 0.0 0.8 0.3 0.5 2.0 1.4 2.1 0.7 1.9 3.5 34.3 0.4 2.9 0.5 0.4 0.0 0.2 62.4 0.2 1.6 0.1 0.5 0.1 1.2 12.3 1.0 0.4 0.6 0.1 0.4 2.6 0.4 0.4 47.3 0.1 0.4 0.7 2.1 0.4 0.9 0.1 1.0 0.9 3.6 2.5 3.2 0.7 0.8 0.5 0.9 0.5 0.2 0.4 2.8 2.9 7.1 1.0 0.1 1.0 4.1 9.7 2.0 1.0 0.5 0.7 0.3 22.0 0.3 6.4 36.8 103.4 0.4 13.2 11.5 11.6 0.2 0.3 0.1 0.5 1.3 5.3 1.3 0.7 8.8 0.4 0.6 0.8 0.6 0.6 0.5 1.7 0.9 1.8 1.0 1.2 2.3 0.8 0.0 0.0 0.0 3.6 9.7 0.6 9.8 0.0 0.1 1.2 1.3 0.5 0.0 5.5 3.7 0.0 0.4 1.0 0.2 0.0 3.5 75.4 2.9 0.6 6.7 0.0 0.0 0.4 4.0 0.7 1.3 0.5 2.1 1.3 0.1 1.1 0.2 97.4 0.0 0.4 0.3 6.1 3.0 295.1 18.4 0.3 38.8 3.6 1.9 682.5 0.1 1.0 0.0 0.4 0.5 0.1 0.4 0.7 1.4 0.3 2.7 1.6 0.2 0.0 0.2 2.5 45.2 3.6 0.4 8.2 0.8 6.3 0.0 0.2 2.1 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 ILRUN "C6orf106, dJ391O22.4, FLJ22195" ENSG00000196821 "Inflammation and lipid regulator with UBA-like and NBR1-like domains" Q9H6K1 6 34587288-34696859 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 211.7" "Cell type enhanced" "Detected in some" "Adipocytes: 9.9;Cardiomyocytes: 73.7;Cytotrophoblasts: 13.7;dendritic cells: 11.8;Hofbauer cells: 15.6;Syncytiotrophoblasts: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034489, HPA034490" Approved Supported "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Centrosome, Cytosol" "HPA034489: AB_10669991, HPA034490: AB_2674186" "unprognostic (3.76e-2)" "unprognostic (2.51e-1)" "unprognostic (7.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (8.40e-2)" "unprognostic (9.94e-2)" "unprognostic (7.57e-2)" "unprognostic (5.68e-2)" "unprognostic (3.55e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" 57.0 35.3 38.4 31.4 39.3 28.6 35.2 48.8 51.6 26.6 36.2 43.4 30.1 29.5 29.0 42.1 27.2 29.3 76.8 39.8 39.8 43.1 77.1 42.5 34.0 41.6 49.9 25.8 30.3 47.3 24.5 30.4 41.5 30.7 29.8 46.7 33.9 32.4 211.7 37.0 35.7 39.4 39.6 31.6 35.0 67.8 43.7 32.9 37.4 187.4 44.8 40.2 28.1 41.4 94.0 41.8 40.3 59.8 95.7 51.9 48.5 63.5 72.3 72.1 89.4 83.0 42.1 107.0 46.1 62.3 99.5 90.7 120.0 52.6 90.3 151.4 47.0 89.2 47.3 80.0 93.4 76.0 96.2 35.4 108.0 73.3 66.4 49.5 58.6 43.9 103.0 43.6 41.7 56.3 52.7 52.7 37.7 152.0 37.3 40.6 52.2 57.0 57.0 91.2 48.6 38.0 93.3 44.9 91.8 82.1 56.5 63.3 60.1 59.1 45.6 63.0 62.7 63.2 154.3 81.8 21.3 66.7 70.1 23.9 3.7 8.1 8.9 6.6 4.7 6.7 6.4 7.1 4.4 8.1 3.5 5.5 4.6 6.2 8.3 2.2 10.0 5.7 38.4 39.3 48.8 51.6 39.8 39.8 41.6 49.9 41.5 39.6 43.7 41.4 9.9 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.7 0.0 0.0 0.0 0.0 13.7 11.8 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 8.6 7.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 21.6 1.6 0.0 0.0 0.0 IMPDH1 "LCA11, RP10, sWSS2608" ENSG00000106348 "Inosine monophosphate dehydrogenase 1" P20839 7 128392277-128410252 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "Disease variant, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 106.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 165.8;Cone photoreceptor cells: 141.8;Horizontal cells: 121.1;Rod photoreceptor cells: 205.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 89.1;eosinophil: 89.1;intermediate monocyte: 104.5;myeloid DC: 59.9;neutrophil: 197.5;non-classical monocyte: 135.9" "Group enriched" "Detected in all" 5 "dendritic cells: 59.9;granulocytes: 197.5;monocytes: 135.9" "Cell line enhanced" "Detected in all" "SK-BR-3: 374.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001400 Approved Supported "Cytosol,Rods & Rings" NA NA 17000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 79: Retina - Phototransduction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Cytosol "Rods & Rings" "HPA001400: AB_1079139" "unprognostic (2.84e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (2.23e-2)" "unprognostic (6.45e-2)" "prognostic unfavorable (7.31e-5)" "unprognostic (6.03e-2)" "prognostic unfavorable (1.12e-7)" "unprognostic (1.24e-1)" "unprognostic (7.45e-3)" "unprognostic (1.03e-2)" "unprognostic (1.79e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.78e-12)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.72e-5)" 54.8 15.9 19.2 33.8 18.5 44.1 38.7 15.7 23.7 18.5 12.7 24.8 8.3 15.1 2.5 30.0 17.7 11.9 23.7 18.1 17.8 15.8 5.7 31.7 25.5 26.3 18.7 20.5 30.1 5.3 26.7 11.4 25.6 27.8 9.8 106.2 29.5 13.1 4.7 23.2 19.1 19.6 17.1 55.9 48.9 16.5 20.0 8.4 11.5 6.2 15.9 29.4 20.4 17.1 111.5 93.2 13.8 102.8 56.5 40.7 38.8 74.1 46.4 61.9 40.1 68.3 35.0 70.8 24.7 111.1 64.4 83.3 78.6 104.1 30.9 25.8 87.1 46.4 66.8 49.1 51.4 62.1 21.1 49.4 49.5 63.2 62.5 29.2 74.5 42.0 46.9 51.8 21.0 76.1 44.1 164.9 77.4 87.7 108.0 51.9 25.2 150.8 27.5 35.1 58.3 55.6 48.0 374.6 68.3 8.6 42.7 119.7 68.5 103.6 37.7 55.0 53.6 38.5 38.3 90.6 53.0 134.0 64.6 11.2 89.1 89.1 22.7 104.5 24.4 15.5 17.9 20.2 59.9 8.9 10.3 12.7 197.5 11.7 135.9 6.0 21.5 58.3 19.2 18.5 15.7 23.7 18.1 17.8 26.3 18.7 25.6 17.1 20.0 17.1 66.8 0.0 11.2 4.6 13.5 8.8 9.3 13.6 9.6 165.8 12.8 9.9 5.1 2.8 8.6 5.5 141.8 3.3 11.1 6.3 5.9 8.1 0.5 4.0 10.9 20.3 9.6 9.7 8.2 17.8 21.3 15.1 44.9 6.5 21.0 46.0 13.6 1.0 46.1 121.1 11.2 10.1 28.5 58.5 21.7 2.0 4.7 38.2 16.0 3.7 65.3 27.3 24.7 2.0 1.5 10.9 3.1 6.8 29.6 21.5 0.8 1.1 7.4 205.5 0.0 9.0 17.3 2.9 16.9 15.8 7.4 2.3 20.4 18.6 11.9 10.3 INF2 "C14orf151, C14orf173, MGC13251" ENSG00000203485 "Inverted formin 2" Q27J81 14 104681146-104722535 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.3;Gastric mucus-secreting cells: 183.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 100.8" "Region enhanced" "Detected in all" "basal ganglia: 224.1" "Low region specificity" "Detected in all" HPA000724 Approved Approved "Nuclear bodies,Endoplasmic reticulum" NA NA 3000000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Nuclear bodies" "HPA000724: AB_1078325" "unprognostic (1.42e-1)" "unprognostic (9.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.00e-2)" "unprognostic (1.49e-2)" "unprognostic (5.90e-3)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.13e-2)" "unprognostic (9.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-2)" "unprognostic (1.36e-3)" "unprognostic (7.24e-2)" "unprognostic (4.01e-1)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.70e-2)" 42.8 21.4 14.0 8.4 29.6 7.5 35.2 18.3 29.5 28.7 1.4 40.4 21.2 24.3 2.3 20.4 20.9 8.9 24.1 14.7 14.7 27.3 30.2 34.3 6.9 30.7 25.5 13.6 15.7 2.0 8.3 11.7 27.5 23.2 4.7 3.3 17.9 7.5 13.7 26.9 31.7 4.4 12.2 31.4 34.7 32.2 26.3 2.1 20.8 1.5 3.4 30.2 28.5 71.2 26.3 92.1 9.9 16.0 7.6 12.2 84.2 49.0 14.5 21.9 14.0 35.5 40.2 3.7 46.6 17.9 17.0 43.3 9.4 22.7 9.5 18.5 26.6 22.0 59.9 23.9 16.5 6.8 21.0 11.4 14.5 15.8 6.8 15.0 24.1 9.1 10.7 10.5 18.0 30.0 10.2 17.9 17.1 18.3 100.8 29.8 19.2 9.4 12.6 38.0 20.5 12.8 26.4 36.7 11.7 8.0 8.0 4.9 49.9 29.4 22.1 45.7 22.5 6.9 3.7 3.7 41.2 12.1 25.1 0.5 2.1 0.1 0.9 0.7 0.7 1.6 3.2 0.6 2.4 1.5 2.5 1.6 1.6 1.2 0.1 5.1 4.0 3.2 14.0 29.6 18.3 29.5 14.7 14.7 30.7 25.5 27.5 12.2 26.3 71.2 48.8 64.1 13.4 10.1 22.5 22.7 17.5 19.0 17.1 0.3 16.5 14.6 14.3 28.6 15.0 3.7 0.0 54.8 5.2 229.3 5.9 24.1 1.2 7.8 8.6 29.8 17.4 17.2 16.7 25.5 87.8 17.9 183.0 18.2 14.7 8.4 25.4 29.8 32.6 0.0 1.9 86.2 12.2 21.8 35.6 2.1 5.6 25.5 8.8 20.6 14.0 55.3 1.0 11.1 89.6 58.1 110.7 4.5 7.8 26.6 90.4 7.3 9.4 2.0 32.9 5.7 36.1 1.1 4.5 8.5 18.8 31.6 9.3 12.9 66.9 38.2 INPP5K SKIP ENSG00000132376 "Inositol polyphosphate-5-phosphatase K" Q9BT40 17 1494577-1516742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Congenital muscular dystrophy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 96.1;Late spermatids: 345.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (7.47e-2)" "prognostic favorable (3.91e-4)" "unprognostic (8.91e-2)" "prognostic favorable (2.33e-5)" "unprognostic (3.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.50e-1)" "unprognostic (7.50e-2)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.47e-6)" "unprognostic (4.71e-2)" "unprognostic (9.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.20e-2)" "unprognostic (4.28e-3)" "unprognostic (1.04e-1)" 34.7 15.2 25.8 12.9 26.0 34.5 29.2 25.3 30.2 19.5 61.5 19.6 10.2 17.0 13.1 17.9 15.3 10.7 28.9 29.8 25.7 16.7 15.0 27.3 18.6 26.9 26.9 17.8 21.9 13.7 14.8 18.6 26.9 19.6 12.7 15.9 18.1 12.9 40.5 30.1 19.4 12.0 25.4 22.8 19.1 20.4 26.9 25.8 30.4 25.2 19.7 18.2 17.9 27.0 14.9 24.0 9.2 18.4 22.5 13.2 12.1 12.0 23.6 15.8 19.6 15.7 9.1 14.6 23.2 22.2 12.5 19.4 22.1 9.6 14.3 35.3 33.0 8.6 18.1 5.9 31.3 7.9 17.0 16.2 24.0 15.8 16.1 10.0 25.3 25.3 9.4 25.9 10.6 12.5 24.5 7.1 3.9 23.9 14.6 19.0 6.7 14.6 12.8 10.3 7.1 18.0 10.2 21.6 24.3 13.0 17.9 7.3 16.2 13.6 13.3 19.8 16.8 12.9 23.4 7.4 14.7 9.1 17.3 104.3 42.2 74.3 48.7 41.9 39.7 27.5 44.5 50.2 36.2 24.4 37.5 41.1 74.7 42.3 66.6 27.0 75.1 62.5 25.8 26.0 25.3 30.2 29.8 25.7 26.9 26.9 26.9 25.4 26.9 27.0 26.1 32.1 14.1 8.5 20.6 30.0 15.7 10.8 18.8 7.8 15.6 12.2 35.8 8.6 11.0 23.9 2.1 13.9 27.5 26.0 13.7 19.4 96.1 10.3 6.9 27.0 17.4 25.2 5.4 24.3 16.4 15.5 13.3 17.4 19.7 7.7 28.5 10.2 11.9 20.2 5.9 17.3 14.2 18.4 19.0 345.7 11.5 13.8 32.0 2.8 37.1 23.1 27.8 2.5 7.0 27.1 23.4 7.5 18.0 13.3 33.2 11.2 6.4 7.9 19.7 12.6 15.3 35.5 20.4 18.1 30.3 31.1 27.2 5.8 13.5 17.4 INSYN2A "C10orf141, FAM196A, FLJ45557, INSYN2" ENSG00000188916 "Inhibitory synaptic factor 2A" Q6ZSG2 10 127135426-127196591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 8.0" "Cell type enhanced" "Detected in single" "Endothelial cells: 1.4" "Group enriched" "Detected in some" 13 "breast cancer: 3.4;glioma: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 2.7;U-87 MG: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035898, HPA035899" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA035898: AB_10964352, HPA035899: AB_10961723" "unprognostic (4.00e-2)" "unprognostic (9.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.66e-3)" "unprognostic (2.18e-1)" "unprognostic (4.70e-2)" "unprognostic (7.30e-2)" "unprognostic (3.62e-1)" "unprognostic (2.18e-2)" "unprognostic (6.96e-2)" "unprognostic (2.38e-1)" "unprognostic (5.47e-2)" "unprognostic (5.07e-2)" "unprognostic (2.86e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" 0.1 0.0 4.5 0.1 6.2 0.0 0.6 2.8 5.8 0.1 1.2 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.1 3.4 5.3 0.3 0.0 0.2 0.0 4.4 5.4 0.7 0.1 0.0 0.2 0.0 4.2 0.7 0.1 1.6 0.2 0.1 0.0 0.1 0.3 0.1 2.6 0.3 0.2 0.6 8.0 1.1 0.1 0.1 0.1 0.2 0.1 2.3 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.5 6.2 2.8 5.8 3.4 5.3 4.4 5.4 4.2 2.6 8.0 2.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IQCJ-SCHIP1 ENSG00000283154 "IQCJ-SCHIP1 readthrough" B3KU38 3 158962235-159897366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 165.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 7.3;Basal squamous epithelial cells: 12.5;Bipolar cells: 11.5;Excitatory neurons: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA003243, HPA003445" Approved Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA003243: AB_1079877, HPA003445: AB_1079875" 22.0 5.1 82.3 9.7 90.6 2.2 15.4 84.9 165.9 9.2 56.6 49.8 4.5 19.6 6.3 15.4 18.2 12.5 57.2 83.9 73.9 17.8 14.3 19.6 2.2 93.5 88.0 4.4 2.7 1.1 7.3 23.6 92.0 17.7 6.8 14.2 6.5 20.4 27.6 5.7 12.8 25.9 81.5 4.3 18.3 4.7 87.2 2.5 5.7 3.2 1.8 35.8 10.8 110.5 87.9 14.8 28.9 34.4 6.6 6.3 25.1 73.6 17.3 59.4 40.5 55.6 20.9 4.4 46.4 24.6 22.6 34.8 11.3 24.9 48.5 72.7 27.6 0.1 31.2 2.8 7.7 4.2 0.5 6.5 20.8 26.5 31.1 49.3 44.5 4.9 0.0 0.3 27.7 3.9 0.3 0.0 24.2 7.0 31.9 10.2 58.4 0.0 57.6 4.7 5.8 26.8 39.8 16.7 21.8 32.9 9.8 0.8 37.6 34.0 47.5 22.9 101.5 0.3 0.5 0.4 19.1 12.4 92.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.3 90.6 84.9 165.9 83.9 73.9 93.5 88.0 92.0 81.5 87.2 110.5 4.7 6.4 0.0 1.0 0.1 1.5 7.3 0.8 12.5 11.5 0.3 0.9 0.6 0.0 1.4 1.8 6.2 0.0 0.1 0.3 0.0 0.9 2.0 2.1 0.8 5.7 0.0 0.0 11.3 0.6 0.0 3.1 0.0 2.3 2.5 0.0 1.8 0.6 0.0 0.0 4.7 0.2 0.0 0.3 1.2 0.6 0.3 1.2 0.0 0.0 0.6 0.5 0.0 0.0 0.6 1.2 0.0 1.2 0.0 1.3 0.0 4.2 2.4 0.6 0.0 2.5 5.4 0.1 0.4 3.5 0.9 0.0 0.5 0.0 0.2 1.6 IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 7.4;Hofbauer cells: 11.1;Smooth muscle cells: 28.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cell line enhanced" "Detected in some" "ASC diff: 20.8;BJ: 15.3;BJ hTERT+: 17.6;fHDF/TERT166: 6.9;REH: 6.8" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" 29.7 8.0 64.6 18.2 85.8 1.5 16.1 50.4 53.4 55.4 17.7 67.6 8.5 60.8 16.1 37.5 45.6 33.2 10.1 54.5 54.3 9.3 2.1 13.3 3.7 65.8 71.4 20.2 2.9 2.7 3.8 11.8 54.4 37.9 17.3 1.7 4.1 39.5 6.7 9.3 22.0 69.1 55.2 7.1 33.7 8.2 89.8 2.3 10.2 8.1 1.8 43.8 21.9 48.8 0.1 0.0 4.2 0.0 20.8 4.1 0.2 15.3 17.6 0.0 0.0 0.4 1.7 0.0 0.1 6.9 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.7 0.0 0.1 0.2 0.0 0.2 4.8 0.4 0.0 0.1 0.0 1.2 0.0 0.6 0.1 0.3 0.0 0.1 0.3 0.5 0.0 0.1 6.8 0.0 0.3 0.0 0.0 0.0 3.1 0.0 2.6 0.0 4.4 0.0 0.5 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 6.0 0.0 0.7 2.2 1.7 0.0 3.9 0.0 0.8 0.0 0.0 0.6 0.9 0.0 0.0 24.0 0.0 5.7 0.1 0.0 0.7 64.6 85.8 50.4 53.4 54.5 54.3 65.8 71.4 54.4 55.2 89.8 48.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 IRAG2 "JAW1, LRMP" ENSG00000118308 "Inositol 1,4,5-triphosphate receptor associated 2" Q12912 12 25004342-25108334 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fertilization, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 60.3;lymphoid tissue: 202.8" "Cell type enhanced" "Detected in some" "Adipocytes: 13.1;B-cells: 6.2;dendritic cells: 42.9;Hofbauer cells: 14.1;Plasma cells: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 210.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Daudi: 634.3;REH: 221.9;U-698: 722.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA002967, HPA007356, HPA018505" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" NA NA 6700 "Cluster 45: Eosinophils - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum, Plasma membrane" "HPA002967: AB_1079161, HPA007356: , HPA018505: AB_1851988" "unprognostic (3.78e-2)" "unprognostic (2.59e-3)" "unprognostic (7.54e-2)" "unprognostic (7.08e-3)" "unprognostic (2.36e-1)" "unprognostic (1.48e-3)" "unprognostic (7.98e-2)" "unprognostic (4.08e-2)" "unprognostic (7.32e-2)" "unprognostic (1.15e-1)" "unprognostic (3.59e-2)" "unprognostic (7.97e-2)" "unprognostic (7.25e-3)" "unprognostic (7.72e-2)" "unprognostic (9.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.59e-2)" 9.6 1.9 8.5 47.2 5.4 60.3 6.5 2.3 5.6 2.4 3.2 10.1 8.7 2.5 2.8 5.2 5.1 7.8 2.4 6.6 2.6 9.4 6.2 7.7 171.7 6.0 4.4 5.7 30.7 1.5 2.4 4.4 6.1 3.4 9.2 1.1 3.6 4.4 1.1 5.8 19.1 4.5 3.6 37.5 10.1 1.0 2.8 95.1 4.9 1.6 202.8 14.5 8.3 4.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 634.3 0.3 0.0 0.0 0.2 0.0 2.4 0.0 22.1 0.0 37.8 0.0 0.1 0.0 49.7 54.2 0.0 0.0 0.7 0.0 0.1 0.0 31.5 7.8 40.6 0.0 0.0 54.5 91.2 0.1 0.0 0.0 221.9 0.3 63.8 0.7 29.7 0.2 0.1 0.2 0.3 0.2 0.1 0.0 36.7 0.5 0.0 1.5 0.0 0.1 40.4 7.8 722.4 0.2 21.8 0.0 80.2 21.0 210.1 23.6 40.8 20.2 66.1 14.9 24.2 22.4 51.0 25.5 25.4 151.3 49.0 51.5 20.8 2.7 20.2 8.5 5.4 2.3 5.6 6.6 2.6 6.0 4.4 6.1 3.6 2.8 4.6 13.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.3;Kupffer cells: 123.0;Macrophages: 126.3;Microglial cells: 114.3;monocytes: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.4;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.0" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.0" "Cell line enhanced" "Detected in many" "ASC diff: 25.9;ASC TERT1: 21.1;HEL: 22.9;HL-60: 30.8;NB-4: 25.1;THP-1: 37.3;U-937: 26.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 18.7 3.8 3.7 12.4 4.1 78.1 11.6 4.1 7.5 9.3 5.4 4.6 1.3 4.0 3.0 3.8 8.0 6.9 7.9 3.2 4.7 3.5 2.8 19.0 4.1 5.6 5.7 3.2 2.5 0.9 8.9 6.8 6.5 5.3 2.8 0.4 6.2 5.6 2.6 3.4 5.6 5.4 5.0 27.5 6.9 1.8 5.6 2.7 5.0 4.6 3.9 8.4 6.6 5.1 0.0 0.0 0.4 0.0 25.9 21.1 0.0 2.9 0.0 1.5 2.3 0.0 2.2 0.0 1.4 5.3 0.0 0.0 3.2 0.0 1.3 0.0 0.0 22.9 1.4 0.0 13.4 30.8 4.0 13.5 0.1 1.2 0.0 0.0 7.6 0.0 0.0 0.0 1.0 0.0 0.0 25.1 1.3 0.0 0.0 0.0 6.4 0.0 0.1 3.3 0.1 0.0 11.6 0.0 1.2 0.1 0.1 37.3 8.2 0.0 0.0 0.0 0.0 0.9 0.2 2.2 0.0 26.8 0.0 12.7 23.4 4.3 0.0 24.2 0.0 0.1 0.0 0.0 11.5 0.7 0.0 0.0 12.9 1.8 42.0 0.1 0.6 7.3 3.7 4.1 4.1 7.5 3.2 4.7 5.6 5.7 6.5 5.0 5.6 5.1 83.3 9.6 19.4 1.3 2.3 1.5 4.8 27.5 6.2 0.3 2.5 1.8 2.8 0.0 46.9 3.7 0.0 0.2 14.8 0.5 0.0 0.6 6.4 0.5 7.5 38.5 0.0 9.7 0.4 1.2 0.4 22.3 18.3 0.5 27.3 0.5 36.4 1.2 9.4 0.0 5.6 1.1 36.7 123.0 12.1 5.3 7.2 126.3 5.4 114.3 96.9 0.2 3.1 2.0 0.6 4.9 0.1 11.3 9.1 1.6 0.0 0.2 35.1 0.1 0.0 18.1 10.2 0.8 1.8 1.2 1.3 0.3 3.5 12.5 0.7 2.5 IRF7 ENSG00000185507 "Interferon regulatory factor 7" Q92985 11 612553-615983 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2;lymphoid tissue: 33.2" "Cell type enriched" "Detected in many" 7 "dendritic cells: 576.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 12 "plasmacytoid DC: 596.9" "Lineage enriched" "Detected in all" 12 "dendritic cells: 596.9" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 15.5;BJ hTERT+ SV40 Large T+ RasG12V: 9.6;Karpas-707: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017694, HPA052757" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB017694: AB_2280489, HPA052757: AB_2681937" "unprognostic (1.39e-2)" "unprognostic (3.26e-2)" "unprognostic (1.08e-3)" "unprognostic (2.45e-1)" "unprognostic (4.52e-2)" "unprognostic (2.73e-1)" "unprognostic (1.04e-2)" "unprognostic (2.52e-2)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (7.08e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (1.71e-10)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (2.58e-1)" "unprognostic (4.71e-2)" 10.4 2.6 1.3 1.6 1.6 1.6 7.5 1.5 2.1 11.2 2.2 8.8 0.0 3.4 0.0 12.7 4.7 2.2 7.9 1.2 1.6 15.6 38.2 14.4 0.9 2.7 1.6 4.7 5.9 0.2 6.2 0.7 2.4 9.2 0.3 0.3 8.8 0.8 11.3 7.8 15.3 0.9 1.3 33.2 8.6 1.9 1.6 1.4 10.7 1.3 2.2 5.1 7.3 1.6 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.4 3.9 15.5 9.6 2.2 0.1 0.0 3.7 0.6 3.7 0.5 0.2 0.1 1.0 0.2 0.0 0.1 0.0 0.2 0.8 0.0 0.0 1.6 0.6 0.0 0.6 0.7 0.1 1.9 0.0 6.5 0.1 0.0 0.7 0.0 0.0 3.1 1.3 0.1 0.2 0.0 0.2 0.1 3.1 0.0 0.6 1.8 0.4 0.3 0.0 1.5 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 12.7 20.4 30.6 8.1 46.1 7.8 16.5 6.7 7.0 24.3 20.8 7.5 8.5 12.9 18.7 49.5 596.9 13.5 19.7 1.3 1.6 1.5 2.1 1.2 1.6 2.7 1.6 2.4 1.3 1.6 1.6 65.0 16.0 19.0 2.9 59.2 34.4 32.3 19.6 18.8 0.4 27.7 20.2 4.3 18.6 18.2 20.2 0.0 6.1 576.1 70.1 9.8 29.9 5.9 20.1 6.3 33.0 26.3 4.8 0.0 16.9 39.0 19.3 40.8 21.2 31.7 20.1 17.9 31.7 37.3 0.0 0.1 42.5 22.4 23.2 65.4 28.9 12.2 67.4 37.4 3.7 65.2 2.7 40.2 1.0 1.3 29.9 73.8 4.9 65.1 24.8 37.6 6.3 25.5 4.6 13.1 8.8 19.8 0.4 5.9 8.0 28.4 24.1 42.7 4.6 18.9 34.6 IRF8 "ICSBP, ICSBP1, IRF-8" ENSG00000140968 "Interferon regulatory factor 8" Q02556 16 85899162-85922606 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 85.5;lymphoid tissue: 244.1" "Cell type enhanced" "Detected in many" "B-cells: 225.8;dendritic cells: 492.3;Kupffer cells: 105.1;Langerhans cells: 366.0;Macrophages: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 2477.4" "Lineage enriched" "Detected in all" 7 "dendritic cells: 2477.4" "Group enriched" "Detected in some" 4 "Daudi: 240.7;THP-1: 382.3;U-698: 928.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002267, HPA002531, CAB013480" Enhanced Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB013480: AB_2533439, HPA002267: AB_1079143, HPA002531: AB_1851904" "unprognostic (2.09e-3)" "unprognostic (7.51e-2)" "unprognostic (5.16e-2)" "unprognostic (1.19e-1)" "unprognostic (7.54e-2)" "unprognostic (3.46e-3)" "unprognostic (3.19e-2)" "unprognostic (5.31e-3)" "unprognostic (1.23e-1)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" "unprognostic (5.31e-2)" "unprognostic (3.14e-3)" "unprognostic (3.97e-2)" "unprognostic (9.66e-3)" "unprognostic (4.04e-1)" "unprognostic (1.10e-2)" 25.9 7.6 4.7 81.4 5.6 85.5 9.3 7.0 6.2 5.6 5.4 27.1 47.1 8.0 3.1 6.7 6.5 19.7 3.8 6.3 5.4 6.1 36.9 27.4 244.1 9.5 8.5 2.5 3.4 1.7 1.7 10.1 10.0 7.7 33.5 0.8 7.1 8.9 2.0 5.0 56.2 13.5 11.3 137.3 22.9 4.8 12.6 61.5 4.1 1.7 224.9 21.8 1.6 14.0 0.9 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 26.0 0.0 240.7 1.5 0.0 0.0 0.1 1.4 0.0 0.2 0.2 2.7 0.1 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.5 0.0 0.0 0.6 21.3 0.2 20.6 0.0 7.5 1.1 27.2 0.0 0.0 0.1 0.1 1.0 0.0 0.2 1.4 0.0 382.3 0.6 0.0 10.9 0.2 0.9 0.3 0.3 928.2 0.0 128.4 0.0 9.1 137.1 3.4 3.3 134.3 4.5 347.0 1.8 2.1 291.2 361.3 3.5 2.8 8.4 111.5 97.3 2477.4 0.7 150.1 4.7 5.6 7.0 6.2 6.3 5.4 9.5 8.5 10.0 11.3 12.6 14.0 3.7 0.0 4.2 0.0 225.8 10.5 0.8 0.0 0.6 0.0 2.4 3.4 1.5 2.8 1.3 0.0 0.0 0.8 492.3 13.0 1.9 0.5 1.5 7.3 7.6 7.6 28.7 7.4 0.6 1.4 5.7 10.8 15.3 12.5 2.5 0.4 1.8 6.5 64.1 0.0 0.2 11.8 0.0 105.1 366.0 4.6 0.3 122.2 44.4 33.7 35.3 0.4 23.7 1.0 0.4 0.1 10.7 0.0 14.1 2.3 34.2 3.5 0.0 0.2 6.6 0.7 6.7 0.7 6.7 0.4 9.2 1.1 23.1 48.8 25.6 2.5 IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.8;heart muscle: 9.8;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Collecting duct cells: 5.5;Hofbauer cells: 4.7;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HEK 293: 1.9;RPTEC TERT1: 7.1;SK-MEL-30: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" "HPA018332: AB_1851920" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (4.93e-4)" "unprognostic (2.48e-2)" "unprognostic (6.50e-2)" "unprognostic (3.46e-1)" "prognostic favorable (3.34e-4)" "unprognostic (3.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-2)" "unprognostic (2.83e-2)" "unprognostic (9.63e-3)" "unprognostic (7.12e-3)" "unprognostic (5.48e-2)" "unprognostic (5.23e-3)" 9.8 0.1 0.2 0.0 0.6 0.0 4.8 1.1 0.3 2.3 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.1 9.8 0.0 1.1 2.7 0.0 1.8 0.1 0.5 0.8 0.2 0.1 1.7 0.2 0.1 0.6 0.2 0.0 1.6 1.9 0.0 2.8 8.9 0.3 0.1 0.2 1.3 0.0 0.4 0.6 2.2 0.6 1.3 1.1 0.0 0.5 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.1 0.0 1.1 4.8 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.3 0.0 1.1 0.5 0.8 0.6 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.5 0.0 7.5 0.4 0.6 1.3 0.0 1.2 5.5 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.8 0.0 0.6 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.7 5.1 0.0 0.1 3.6 0.0 0.6 1.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.3 0.1 0.5 0.0 1.0 0.1 0.0 0.0 0.0 0.0 ISCA2 "HBLD1, ISA2" ENSG00000165898 "Iron-sulfur cluster assembly 2" Q86U28 14 74493756-74497106 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030492 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA030492: AB_10603772" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "unprognostic (5.73e-2)" "unprognostic (5.62e-2)" "unprognostic (2.51e-1)" "unprognostic (5.89e-3)" "unprognostic (6.03e-3)" "unprognostic (7.98e-2)" "unprognostic (1.66e-1)" "unprognostic (2.59e-2)" "unprognostic (1.31e-2)" "unprognostic (2.21e-1)" "prognostic favorable (1.68e-7)" "unprognostic (3.98e-2)" "unprognostic (1.47e-1)" "prognostic favorable (8.98e-5)" "unprognostic (5.23e-2)" 15.1 33.9 20.3 9.7 20.6 15.5 16.9 22.4 23.9 13.7 27.4 16.9 14.2 11.0 46.4 15.4 19.5 7.6 34.3 19.5 21.2 30.6 22.0 12.9 17.0 21.2 21.1 18.1 18.1 12.9 23.4 12.8 21.3 18.5 17.5 19.1 17.8 12.1 38.3 13.3 16.0 8.4 21.1 20.0 18.1 20.6 22.6 18.5 26.0 29.2 17.4 13.7 13.4 21.5 43.4 30.7 28.4 18.1 25.5 37.2 35.9 19.7 26.3 30.2 36.3 36.3 39.3 21.8 25.3 16.6 38.2 30.7 27.8 25.9 40.7 30.7 20.2 13.7 13.1 39.6 38.3 17.7 30.2 31.2 29.0 18.2 20.6 28.0 30.8 44.4 18.2 25.5 32.7 51.0 42.9 34.5 21.0 60.2 28.3 29.8 31.9 21.8 42.6 34.1 19.1 19.6 20.8 24.4 31.8 30.5 60.2 20.9 16.9 17.1 39.5 25.3 17.7 43.3 60.3 40.2 28.0 20.6 25.4 130.8 109.1 159.0 91.8 108.0 93.5 172.3 127.6 111.6 111.0 165.4 148.5 122.1 87.5 101.5 106.6 218.1 157.4 161.3 20.3 20.6 22.4 23.9 19.5 21.2 21.2 21.1 21.3 21.1 22.6 21.5 25.2 19.2 20.4 7.2 36.2 15.4 27.2 74.9 13.6 22.1 36.2 38.2 113.3 22.8 42.7 33.1 12.5 70.8 28.8 45.5 146.8 62.0 41.0 38.3 17.6 27.2 29.3 73.2 4.4 55.0 70.1 28.8 24.5 18.1 12.6 31.8 28.9 42.4 81.5 28.6 5.5 36.3 63.1 33.2 18.3 19.3 33.5 30.4 8.8 2.8 49.0 69.8 41.2 3.0 7.2 59.5 50.8 18.0 25.0 40.2 51.4 133.5 78.6 31.6 13.1 15.1 25.1 107.2 63.7 25.4 13.2 25.4 30.7 43.1 42.3 27.6 ISCU "hnifU, ISU2, NIFUN" ENSG00000136003 "Iron-sulfur cluster assembly enzyme" Q9H1K1 12 108562582-108569368 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1430.2;Late spermatids: 969.5;Proximal tubular cells: 1315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006329, HPA038602, HPA057592" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB006329: AB_425907, HPA038602: AB_2676109, HPA057592: AB_2683478" "unprognostic (1.72e-1)" "prognostic favorable (4.90e-7)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (2.43e-1)" "unprognostic (3.15e-2)" "unprognostic (1.33e-1)" "unprognostic (6.69e-3)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-3)" "unprognostic (2.49e-2)" "prognostic favorable (2.73e-7)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-3)" "prognostic favorable (6.12e-4)" 174.8 387.6 186.3 89.8 187.5 98.2 166.8 209.9 216.8 174.4 222.2 222.9 88.8 170.2 148.8 91.2 142.5 106.5 507.1 186.2 223.0 341.3 119.9 138.3 138.9 223.4 192.5 169.2 106.2 286.0 228.9 111.1 214.4 150.5 112.0 58.9 123.7 196.1 422.3 111.6 142.7 122.2 187.0 163.9 169.2 123.2 188.0 151.6 184.4 381.5 138.3 179.0 133.4 177.0 47.5 113.8 78.9 47.3 277.4 211.6 191.7 92.8 152.2 69.7 65.7 84.9 66.0 47.4 77.9 128.5 74.6 67.5 76.2 106.8 62.5 147.2 82.0 51.8 60.7 190.6 161.5 124.4 59.0 206.6 234.3 75.4 149.3 176.8 107.7 100.7 98.3 148.8 147.8 102.9 98.1 225.4 76.4 70.9 165.7 64.0 52.5 205.3 204.5 134.6 67.4 62.4 67.5 39.7 108.7 98.3 102.2 99.4 92.3 70.3 59.0 56.8 47.8 175.9 207.8 146.3 109.5 91.8 72.4 478.2 182.1 567.9 224.5 200.5 269.2 564.4 292.6 292.7 128.4 516.7 366.2 305.0 554.2 207.5 239.3 225.2 334.2 400.8 186.3 187.5 209.9 216.8 186.2 223.0 223.4 192.5 214.4 187.0 188.0 177.0 129.8 76.9 158.9 19.9 206.3 98.1 148.6 227.0 98.4 46.2 137.5 212.3 674.1 145.8 148.6 233.6 10.4 453.7 142.2 120.1 1430.2 154.3 433.2 78.1 76.5 140.8 75.0 165.5 52.6 149.8 164.0 165.5 64.2 37.1 116.5 89.1 126.0 112.3 263.0 45.4 53.7 117.6 193.3 140.1 110.2 969.5 202.0 129.9 249.1 23.4 502.4 167.9 163.7 14.6 26.0 141.3 96.3 308.4 299.4 171.8 235.9 1315.1 160.4 45.8 223.5 97.4 158.1 294.5 242.1 92.6 93.1 475.2 153.6 154.2 139.8 177.7 ISL2 FLJ10160 ENSG00000159556 "ISL LIM homeobox 2" Q96A47 15 76336773-76342475 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.6;prostate: 2.3;vagina: 3.5" "Cell type enriched" "Detected in some" 7 "Cone photoreceptor cells: 27.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 9.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 15.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "spinal cord: 1.8" HPA075192 Approved "Rods & Rings" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Rods & Rings" "HPA075192: AB_2686738" "unprognostic (7.30e-2)" "unprognostic (7.96e-2)" "unprognostic (9.01e-3)" "unprognostic (4.44e-3)" "unprognostic (1.44e-1)" "unprognostic (7.77e-2)" "unprognostic (1.25e-2)" "unprognostic (1.45e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-1)" "unprognostic (9.03e-2)" "unprognostic (3.93e-2)" "unprognostic (3.55e-15)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "unprognostic (4.07e-1)" "unprognostic (2.26e-1)" 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.0 1.9 0.8 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.2 0.0 0.0 0.0 2.6 0.0 0.2 2.3 0.0 1.4 1.8 0.0 0.0 0.6 1.2 0.0 0.0 0.5 1.6 0.8 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.8 1.5 1.8 0.0 1.7 0.1 0.1 1.5 4.5 2.1 1.2 1.5 3.4 0.7 3.3 2.1 0.0 1.1 1.9 6.4 0.1 0.2 3.2 15.4 1.6 4.0 4.1 1.4 3.6 4.3 0.0 0.8 0.0 0.0 0.0 0.0 4.8 5.1 2.6 0.3 0.1 4.4 8.4 0.0 0.6 2.8 2.7 2.0 4.4 0.0 0.6 4.9 5.0 3.0 0.0 0.0 0.9 0.3 8.2 0.0 1.5 3.2 0.6 4.3 3.8 4.1 2.0 1.1 2.5 0.0 0.0 0.8 0.0 0.1 0.9 0.0 0.8 0.0 0.5 0.1 1.7 0.1 0.0 9.5 0.0 3.5 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.1 0.8 0.2 0.2 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.6 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 27.1 0.1 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 3.5 0.6 0.0 0.0 0.0 2.1 0.0 0.2 0.5 1.5 1.0 0.0 0.0 0.3 0.2 0.0 0.0 3.0 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ISOC2 FLJ23469 ENSG00000063241 "Isochorismatase domain containing 2" Q96AB3 19 55452985-55462343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 284.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.2;Proximal tubular cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 270.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043142 Enhanced Approved Mitochondria,Cytosol NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Cytosol "HPA043142: AB_10794653" "unprognostic (2.74e-1)" "unprognostic (8.38e-3)" "unprognostic (7.34e-2)" "unprognostic (3.09e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-1)" "unprognostic (3.09e-1)" "unprognostic (5.82e-2)" "unprognostic (8.59e-2)" "unprognostic (9.90e-3)" "unprognostic (2.24e-1)" "unprognostic (2.42e-1)" "unprognostic (9.20e-2)" "unprognostic (2.09e-2)" 50.4 55.6 39.7 20.0 41.2 21.4 38.3 42.7 52.4 25.4 48.1 62.1 36.2 28.4 8.1 52.2 25.8 17.2 69.5 39.5 43.9 101.4 284.3 26.4 19.2 46.6 44.4 23.3 44.4 39.9 46.3 9.3 43.7 40.9 16.3 3.3 41.8 28.7 95.7 37.6 37.2 16.8 42.6 50.8 41.4 65.6 42.1 9.9 39.1 49.0 14.0 41.6 30.3 44.4 52.8 78.1 20.1 55.6 13.6 28.4 67.7 37.9 36.7 45.7 46.4 40.0 88.2 98.6 66.2 42.2 44.0 51.1 39.7 46.6 14.6 38.9 270.2 57.6 17.8 128.0 55.6 63.2 163.5 42.5 44.2 29.4 22.0 20.4 42.4 39.3 93.6 61.1 28.9 101.9 0.3 73.6 32.4 113.2 217.9 72.1 44.4 126.0 75.0 47.7 24.7 70.5 35.5 75.3 41.4 11.9 63.8 109.4 32.4 34.0 48.5 38.8 44.7 78.7 73.0 78.7 52.2 79.4 58.3 0.7 16.0 0.9 12.7 33.8 12.6 18.7 11.6 16.2 29.5 12.6 11.5 11.8 0.7 24.3 27.8 24.1 15.2 15.0 39.7 41.2 42.7 52.4 39.5 43.9 46.6 44.4 43.7 42.6 42.1 44.4 25.4 6.4 6.3 5.5 38.0 59.5 65.3 148.8 32.5 12.5 51.7 56.5 20.8 48.6 50.3 62.5 2.1 32.5 19.1 200.1 162.4 65.1 44.5 37.8 39.0 36.9 71.3 46.9 3.5 68.1 105.5 44.2 63.7 25.1 45.2 43.2 28.5 272.2 96.0 13.5 5.4 225.4 87.5 44.5 50.6 43.6 38.8 39.0 62.2 2.8 28.0 53.1 21.6 6.6 12.8 56.4 125.8 30.9 80.5 128.7 253.7 479.9 26.1 10.0 26.3 32.0 39.0 183.8 16.4 69.6 68.6 21.6 19.4 123.4 190.7 74.8 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 47.1;lymphoid tissue: 74.1" "Group enriched" "Detected in many" 4 "B-cells: 86.3;dendritic cells: 151.5;Erythroid cells: 169.3;Macrophages: 72.0;monocytes: 73.8;NK-cells: 126.7;Plasma cells: 141.6;T-cells: 129.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 164.0;HEL: 308.1;JURKAT: 142.3;MOLT-4: 373.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 12.9" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" 3.3 2.3 1.2 31.5 0.5 47.1 3.8 4.1 1.5 12.7 3.0 8.7 8.7 3.3 1.4 2.3 1.5 9.8 1.5 4.1 1.3 2.7 5.7 12.7 37.2 1.4 1.6 1.4 1.5 0.9 0.4 14.7 2.9 3.5 10.3 8.6 2.9 2.5 0.6 1.2 11.7 5.2 0.9 45.5 10.4 0.8 2.4 74.1 2.0 0.9 26.1 9.5 1.4 1.3 0.3 1.3 4.6 0.1 38.9 55.0 0.0 42.3 46.7 19.5 42.0 0.0 0.0 32.4 0.2 164.0 17.4 23.4 14.0 0.7 22.3 0.0 3.4 308.1 1.1 0.0 4.0 123.4 6.8 39.2 0.0 1.2 0.0 20.5 2.3 142.3 0.1 45.5 12.7 0.0 373.6 117.9 3.7 0.0 0.2 78.1 20.3 5.1 0.0 0.0 8.2 2.6 0.1 0.4 1.4 1.6 0.0 82.9 23.2 6.5 4.1 0.7 8.5 90.9 77.5 18.6 3.7 59.5 90.3 29.5 55.0 137.4 42.0 131.3 32.1 37.3 46.9 52.4 66.0 33.0 26.5 33.1 7.1 32.2 139.6 17.5 13.4 65.2 1.2 0.5 4.1 1.5 4.1 1.3 1.4 1.6 2.9 0.9 2.4 1.3 2.8 0.0 6.7 0.0 86.3 0.3 0.2 1.2 0.0 2.3 1.1 1.4 1.2 2.8 1.8 0.0 6.2 0.1 151.5 0.1 0.0 0.0 0.0 4.4 6.5 1.4 0.0 169.3 9.4 0.0 0.3 6.3 7.1 6.4 18.9 0.3 1.8 0.2 5.9 0.0 0.5 0.1 0.0 24.5 4.4 0.0 0.6 72.0 0.0 7.5 73.8 0.2 126.7 15.6 0.3 0.0 0.4 0.0 141.6 0.3 0.0 0.2 0.8 6.4 0.0 0.7 8.3 0.7 1.2 0.3 0.6 0.4 129.9 0.4 0.2 0.2 ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716043 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 262.3" "Group enriched" "Detected in many" 6 "Astrocytes: 87.5;Cardiomyocytes: 124.5;Sertoli cells: 164.3;Skeletal myocytes: 65.8;Smooth muscle cells: 110.6" "Cancer enhanced" "Detected in all" "glioma: 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 309.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1200000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: AB_1851823" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.00e-3)" "unprognostic (3.02e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (2.20e-2)" "unprognostic (3.57e-1)" "prognostic favorable (1.75e-4)" "unprognostic (2.85e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.10e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (9.59e-5)" 133.4 8.2 18.5 18.5 21.2 1.8 69.0 15.9 30.2 28.7 16.1 97.8 17.7 45.5 12.3 23.9 56.1 30.8 157.9 34.5 17.8 11.5 10.2 15.5 6.4 21.2 21.1 19.1 5.1 6.1 12.6 1.9 20.3 33.9 8.9 2.4 14.9 37.3 262.3 16.0 27.4 95.2 16.4 10.2 35.2 8.9 23.8 3.4 26.1 154.1 3.3 46.5 25.5 21.0 0.2 4.1 7.5 12.3 66.5 13.4 0.7 5.4 8.7 11.7 11.8 8.4 6.5 2.3 7.4 3.4 0.9 1.1 5.1 0.3 10.0 0.2 3.8 0.8 2.8 3.2 0.5 0.3 2.7 19.1 0.2 64.2 0.3 309.1 0.2 2.2 0.9 1.6 37.8 5.3 0.3 3.1 20.9 1.7 0.4 0.1 28.7 0.6 0.2 0.2 0.9 2.8 0.6 0.2 48.0 4.0 0.9 13.9 0.0 1.3 12.4 0.8 8.4 3.2 2.2 0.9 57.8 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.5 21.2 15.9 30.2 34.5 17.8 21.2 21.1 20.3 16.4 23.8 21.0 11.9 0.0 0.0 87.5 0.3 1.9 0.5 0.1 0.6 2.4 1.2 3.4 124.5 2.8 0.0 1.8 4.2 0.0 0.3 0.7 0.0 0.3 0.3 1.1 1.2 9.5 7.7 0.4 17.6 0.0 0.1 5.0 0.5 1.1 0.0 6.2 0.7 1.4 0.6 0.0 9.4 1.8 0.0 1.9 2.7 0.1 6.5 2.2 3.6 9.4 0.0 3.4 0.0 6.6 3.7 0.3 0.1 6.4 0.1 0.8 2.6 0.8 0.1 0.6 164.3 65.8 110.6 4.1 2.9 0.7 2.3 0.1 0.5 0.3 0.9 0.3 ITGAL "CD11A, LFA-1" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 118.6;monocytes: 36.8;NK-cells: 152.4;Plasma cells: 46.6;T-cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 121.7" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "HMC-1: 608.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" 4.2 1.4 0.3 36.7 0.5 36.8 2.3 0.3 1.0 2.4 0.5 5.5 6.0 2.3 1.0 2.5 3.0 7.0 1.4 0.3 0.4 2.6 10.6 22.0 62.4 1.6 1.1 1.3 1.0 0.5 1.2 3.0 1.4 2.4 8.6 0.0 5.3 1.4 0.9 1.4 19.7 3.6 0.7 64.9 8.6 1.0 1.6 55.2 3.5 0.9 46.4 6.9 2.3 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.1 0.0 1.1 608.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 134.3 0.0 0.0 43.3 3.5 0.0 0.0 0.0 0.1 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.4 26.0 0.0 0.0 0.0 0.0 0.0 36.6 12.5 0.0 0.1 3.8 0.0 5.3 24.4 17.0 56.6 48.0 27.7 4.8 21.4 42.7 22.3 1.7 9.4 29.7 14.3 24.2 121.7 6.0 15.6 43.6 0.3 0.5 0.3 1.0 0.3 0.4 1.6 1.1 1.4 0.7 1.6 2.1 1.2 6.4 10.5 0.7 19.1 0.8 0.3 0.0 0.0 0.4 1.2 1.0 1.9 0.0 1.9 1.8 0.0 0.2 118.6 0.3 0.0 0.1 0.5 4.1 0.6 2.3 0.0 4.8 3.6 0.0 0.6 1.4 1.1 0.9 5.1 0.1 5.3 4.9 19.3 0.0 2.8 0.2 0.0 30.0 3.4 0.7 0.0 31.5 1.8 15.9 36.8 0.1 152.4 0.5 1.6 0.0 0.0 0.0 46.6 0.1 0.9 0.3 6.7 0.9 0.0 1.2 0.7 0.2 0.2 0.1 0.3 0.7 84.9 0.1 0.0 0.2 ITGAM "CD11B, CR3A, MAC-1" ENSG00000169896 "Integrin subunit alpha M" P11215 16 31259967-31332892 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Innate immunity" "Integrin, Receptor" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 182.8" "Group enriched" "Detected in many" 4 "dendritic cells: 45.4;granulocytes: 35.5;Hofbauer cells: 47.2;Kupffer cells: 117.7;Langerhans cells: 45.5;Macrophages: 83.2;Microglial cells: 41.2;monocytes: 87.4;NK-cells: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HMC-1: 50.0;NB-4: 19.9;U-937: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002274, CAB025091, CAB072870" Enhanced NA NA 1000000 "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB025091: , CAB072870: AB_2665722, HPA002274: AB_1078435" "unprognostic (1.82e-2)" "unprognostic (1.70e-2)" "unprognostic (8.78e-2)" "unprognostic (2.54e-2)" "unprognostic (2.40e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (3.29e-3)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.93e-5)" "unprognostic (9.89e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (3.99e-2)" "unprognostic (5.03e-2)" 13.4 4.7 3.4 24.7 3.5 182.8 3.0 4.5 4.2 3.3 4.8 3.0 2.2 2.0 0.7 2.6 2.3 5.9 2.9 3.6 5.1 1.0 3.5 16.4 7.4 6.7 5.7 1.6 2.3 1.3 0.1 7.7 7.3 1.5 3.4 0.3 2.4 2.2 1.4 1.7 3.5 11.2 6.5 13.1 3.1 1.4 8.6 5.2 1.0 3.1 10.4 8.0 0.2 10.8 0.8 1.8 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.5 0.8 1.3 0.9 0.0 0.4 0.1 0.0 0.4 0.0 7.6 0.0 1.0 0.0 0.0 0.0 1.8 50.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.3 0.1 1.0 0.0 2.2 0.0 0.0 0.0 0.5 0.4 0.0 0.2 4.3 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 22.6 0.1 93.3 55.7 70.2 31.1 20.9 1.9 4.8 3.3 9.5 9.5 1.0 0.9 7.7 58.4 54.4 3.2 0.6 1.2 27.0 3.4 3.5 4.5 4.2 3.6 5.1 6.7 5.7 7.3 6.5 8.6 10.8 1.4 3.2 9.8 0.7 9.3 1.1 0.3 1.5 0.0 0.0 1.8 3.8 2.3 4.3 1.8 0.0 0.0 0.3 45.4 0.0 0.0 1.2 0.5 0.3 0.4 1.6 3.6 9.4 1.0 0.0 0.7 1.1 1.1 0.5 35.5 0.5 2.2 1.2 47.2 0.0 1.0 0.1 0.0 117.7 45.5 1.8 0.3 83.2 0.0 41.2 87.4 0.0 75.2 3.0 0.3 0.9 0.0 0.0 4.5 0.5 0.0 0.2 0.9 0.0 13.1 1.2 0.5 0.7 0.9 0.5 1.0 0.8 14.9 0.0 0.3 0.2 ITGB1BP1 "ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B" ENSG00000119185 "Integrin subunit beta 1 binding protein 1" O14713 2 9403475-9423528 "Predicted intracellular proteins" "Angiogenesis, Biomineralization, Cell adhesion, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 391.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067348, HPA071538" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA067348: AB_2732765, HPA071538: AB_2686413" "unprognostic (2.21e-1)" "unprognostic (8.31e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.39e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (4.67e-5)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (6.46e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (7.10e-5)" "unprognostic (3.75e-2)" "unprognostic (2.01e-1)" "unprognostic (1.14e-3)" "unprognostic (4.08e-3)" 113.7 23.2 45.5 19.3 63.1 31.3 60.4 50.3 58.0 43.7 49.3 37.3 13.6 31.0 26.6 20.9 24.3 22.6 37.3 46.4 48.3 50.2 13.3 22.8 22.1 48.2 47.0 22.3 11.8 26.2 19.1 24.2 49.9 18.5 24.2 27.5 15.5 23.7 29.8 29.7 19.1 35.9 41.8 15.2 22.9 9.4 54.3 27.0 22.4 33.5 25.7 30.4 32.5 52.7 53.5 35.4 43.4 51.5 148.9 131.2 23.3 94.9 66.2 83.8 66.1 49.5 33.1 55.6 43.1 135.9 56.1 50.1 66.3 62.7 92.8 158.6 30.2 53.2 43.2 61.1 54.1 42.2 57.4 70.5 49.5 78.4 56.5 75.2 76.6 43.0 29.9 46.1 109.0 44.6 74.7 25.5 35.9 90.3 53.9 39.4 59.1 51.4 88.5 40.6 44.1 45.0 54.8 40.3 71.3 38.9 30.5 32.1 48.6 73.8 54.5 103.3 105.7 46.8 111.0 89.0 106.1 54.8 54.5 86.1 43.1 56.0 54.9 54.0 52.5 40.1 46.6 53.2 56.8 33.0 35.2 45.7 9.3 50.4 41.1 52.8 61.7 53.1 45.5 63.1 50.3 58.0 46.4 48.3 48.2 47.0 49.9 41.8 54.3 52.7 90.0 28.9 18.1 18.3 47.1 61.2 40.6 70.4 40.9 25.2 30.4 41.8 104.3 22.8 35.1 38.6 2.1 45.0 70.7 16.1 391.3 72.0 26.3 31.3 51.9 85.5 33.1 49.4 61.6 72.7 73.9 98.6 25.5 30.9 41.7 44.4 53.6 21.6 91.4 35.3 47.3 30.4 32.6 45.0 88.5 25.7 54.3 51.7 97.8 15.9 95.6 64.2 121.5 25.6 40.1 108.9 27.0 57.2 42.7 35.2 24.7 88.4 35.6 30.6 92.1 49.0 102.4 27.8 19.0 47.5 63.1 31.5 63.0 70.7 35.2 60.4 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "B-cells: 45.1;dendritic cells: 62.3;NK-cells: 134.9;Plasma cells: 115.9;T-cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 99 "Karpas-707: 4821.4;RPMI-8226: 3980.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" 1.6 1.4 1.7 20.0 1.8 15.5 1.9 1.7 2.2 2.7 2.0 9.7 11.7 1.6 2.8 6.4 2.9 3.9 0.8 1.5 2.0 4.7 5.3 6.6 29.2 2.3 1.8 0.7 1.2 0.7 1.3 0.5 2.0 1.7 9.5 1.0 4.1 2.3 0.7 11.9 17.3 2.4 1.9 30.0 8.2 0.6 2.8 8.6 3.1 0.6 26.5 6.2 2.9 2.1 0.1 0.0 0.0 0.3 0.1 0.7 1.4 0.5 0.0 0.0 0.5 0.0 2.1 44.5 0.8 0.0 0.0 9.4 0.0 0.3 0.0 16.5 0.0 1.5 0.0 0.0 0.0 1.0 18.5 1.0 1.8 0.2 0.1 0.6 0.0 2.2 0.4 4821.4 0.0 1.6 0.9 7.0 0.3 41.7 0.1 1.8 0.0 3980.8 0.0 1.2 1.9 0.6 0.1 1.8 0.5 0.0 0.8 10.4 0.0 0.3 0.6 0.9 0.0 8.9 17.9 3.8 3.8 2.6 1.6 80.7 5.6 97.7 52.0 1.4 38.2 28.1 51.8 63.0 44.5 29.8 44.5 44.4 1.5 23.7 0.4 11.9 71.8 17.3 1.7 1.8 1.7 2.2 1.5 2.0 2.3 1.8 2.0 1.9 2.8 2.1 1.0 3.2 5.5 1.3 45.1 2.2 0.3 1.7 3.4 0.1 1.3 1.0 0.5 2.8 1.3 7.3 4.2 0.1 62.3 0.6 7.9 0.3 0.0 1.2 0.4 0.9 0.0 2.1 0.0 0.5 0.1 1.3 2.6 2.4 29.2 0.1 0.4 2.2 13.3 0.0 0.1 0.5 0.0 3.7 10.3 0.3 0.0 17.3 7.2 1.9 13.3 7.0 134.9 0.0 0.5 0.9 1.7 0.0 115.9 0.2 0.0 7.6 0.2 0.8 0.0 1.0 8.2 0.2 1.4 3.3 3.7 0.1 62.5 0.1 1.2 1.4 ITIH6 "ITIH5L, UNQ6369" ENSG00000102313 "Inter-alpha-trypsin inhibitor heavy chain family member 6" Q6UXX5 X 54748918-54798255 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "melanoma: 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "WM-115: 50.7" HPA000506 Uncertain "Secreted to blood" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 35: Glandular cells - Unknown function" "HPA000506: AB_2666007" "unprognostic (3.40e-1)" "unprognostic (1.04e-1)" "unprognostic (9.73e-3)" "unprognostic (7.24e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-3)" "unprognostic (9.81e-2)" "unprognostic (2.66e-1)" "unprognostic (1.02e-1)" "unprognostic (6.33e-2)" "unprognostic (4.14e-4)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (2.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 50.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 106.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.9" "Group enriched" "Detected in all" 5 "granulocytes: 42.9;monocytes: 25.9" "Cell line enhanced" "Detected in all" "WM-115: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA055230: AB_2682748" "unprognostic (1.93e-3)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "prognostic favorable (8.56e-4)" "unprognostic (4.27e-1)" "unprognostic (2.04e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.24e-2)" "unprognostic (2.86e-2)" "unprognostic (8.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-3)" "unprognostic (2.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.20e-1)" "unprognostic (7.25e-3)" 60.0 27.2 88.3 15.5 105.9 17.3 45.3 84.7 92.7 57.0 57.2 60.1 44.4 66.8 11.6 24.8 30.3 19.4 59.2 92.5 80.7 35.6 48.3 31.6 9.0 90.2 95.8 27.1 30.7 14.8 20.6 6.8 83.0 38.8 16.4 9.3 21.0 21.7 40.9 22.2 58.5 23.4 83.2 38.1 34.2 29.5 100.4 6.9 25.4 16.1 6.6 62.5 35.0 100.7 28.1 56.6 10.3 26.3 22.5 12.6 27.8 11.8 17.5 22.9 13.8 32.8 48.9 17.7 57.4 18.6 8.7 32.5 29.6 50.3 7.2 65.9 13.1 39.2 14.6 28.5 16.8 17.9 41.5 8.2 29.5 11.6 26.3 9.9 22.8 18.0 21.9 19.8 11.3 74.6 15.5 25.5 22.0 36.4 25.5 29.1 15.1 26.3 15.5 46.3 28.0 35.5 29.6 59.0 49.5 7.8 79.5 21.7 18.0 15.9 17.3 27.0 18.9 19.3 19.1 11.4 14.6 13.8 110.8 5.3 9.8 18.2 3.2 15.4 1.9 3.3 2.0 2.1 7.0 1.0 1.2 2.2 42.9 2.4 25.9 3.5 3.0 5.1 88.3 105.9 84.7 92.7 92.5 80.7 90.2 95.8 83.0 83.2 100.4 100.7 11.8 12.8 11.1 32.0 10.8 7.4 7.5 8.3 2.8 10.2 11.8 7.6 24.3 17.2 5.1 29.5 18.8 9.7 12.9 73.5 13.7 19.2 12.7 18.1 12.5 12.4 28.8 5.9 45.1 27.3 10.0 8.9 13.3 21.2 16.5 9.2 13.9 31.3 19.4 6.7 21.6 24.8 4.1 44.7 11.8 30.3 14.9 30.5 26.6 16.9 23.2 17.2 18.6 31.7 46.5 44.6 38.7 48.2 13.2 15.2 106.6 23.0 3.3 13.7 19.7 7.4 17.8 4.3 14.3 7.0 4.4 6.8 12.7 10.3 34.5 11.0 ITSN1 "ITSN, MGC134948, MGC134949, SH3D1A, SH3P17" ENSG00000205726 "Intersectin 1" Q15811 21 33642400-33899861 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 217.4;Inhibitory neurons: 151.9;Rod photoreceptor cells: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 5.5;non-classical monocyte: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 115.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018007 Approved Supported "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA018007: AB_1851836" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (3.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (3.94e-2)" "unprognostic (7.33e-3)" "unprognostic (1.31e-2)" "unprognostic (3.23e-1)" "unprognostic (3.25e-2)" "unprognostic (1.16e-2)" "unprognostic (6.78e-3)" "unprognostic (2.37e-1)" "unprognostic (6.02e-2)" "unprognostic (5.64e-2)" 55.5 15.5 18.0 9.9 18.4 6.8 27.9 16.4 26.2 19.8 22.8 14.7 8.9 20.3 12.0 11.4 16.7 19.8 20.9 18.3 14.0 10.9 26.4 11.5 6.8 14.5 13.6 19.6 5.0 7.0 6.7 24.4 14.9 14.5 11.0 28.5 7.9 22.3 22.0 11.9 9.7 18.4 8.8 15.4 11.1 12.3 17.0 5.0 10.3 22.0 3.9 15.4 13.4 14.1 36.3 14.9 70.4 23.4 32.3 30.8 115.3 35.8 34.4 20.6 19.8 56.7 27.0 8.5 28.3 43.1 42.7 13.7 42.2 24.9 22.0 3.5 18.6 10.3 30.9 26.7 24.4 7.4 9.9 30.5 22.0 38.6 21.2 23.5 55.3 9.8 13.7 5.8 33.4 8.2 10.3 9.8 104.5 12.6 11.3 13.2 33.7 17.6 30.9 14.7 13.2 14.4 51.4 10.6 12.6 44.6 13.0 7.2 50.2 22.9 30.9 18.1 12.5 7.0 20.8 7.9 20.8 22.9 26.0 0.0 4.2 5.5 0.3 3.2 0.3 0.0 0.5 0.1 1.3 0.0 0.2 0.1 0.2 0.1 5.1 0.3 0.0 0.8 18.0 18.4 16.4 26.2 18.3 14.0 14.5 13.6 14.9 8.8 17.0 14.1 19.8 25.6 18.6 217.4 1.8 18.1 22.6 10.8 36.5 73.1 12.2 8.1 81.8 18.6 14.5 11.0 91.8 20.8 1.1 22.4 0.0 19.9 10.2 13.3 67.7 21.3 9.1 47.4 110.9 12.5 28.0 31.9 19.4 21.0 2.5 30.7 28.2 54.2 55.6 65.6 151.9 7.2 20.3 30.0 10.9 8.6 24.8 27.3 10.6 74.0 10.8 46.9 0.0 80.4 46.4 37.1 10.3 71.5 3.1 18.3 16.8 16.6 18.8 146.2 13.1 20.1 39.7 32.4 47.7 8.9 11.8 15.6 2.7 21.4 10.5 27.2 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 4 "dendritic cells: 136.9;Kupffer cells: 125.8;Macrophages: 166.6;monocytes: 204.7;T-cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Cell line enriched" "Detected in some" 5 "HMC-1: 28.0" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" 13.9 4.5 0.9 68.7 1.0 20.9 5.6 2.4 2.1 5.6 2.3 16.8 17.8 3.5 1.5 8.5 4.3 20.4 3.2 0.7 0.9 3.4 9.8 43.3 31.1 1.3 0.9 1.8 2.9 1.0 1.6 7.8 1.0 4.4 22.7 0.3 2.9 3.6 1.2 4.6 32.1 15.3 1.0 60.0 9.4 1.5 1.0 24.3 2.9 7.8 31.6 24.9 3.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 2.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 3.1 0.4 3.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 137.4 1023.8 3529.6 60.1 616.5 386.5 7.1 107.4 113.7 1017.6 2.9 124.7 103.1 2121.1 24.3 310.3 765.1 191.3 844.1 0.9 1.0 2.4 2.1 0.7 0.9 1.3 0.9 1.0 1.0 1.0 1.1 1.2 6.4 34.2 0.0 6.9 0.0 0.2 0.0 0.0 0.3 0.9 1.3 0.0 2.8 5.6 1.8 0.0 0.3 136.9 0.9 0.0 0.1 1.0 0.4 0.2 1.3 0.0 5.0 0.0 0.4 0.4 1.8 2.6 0.6 15.2 0.0 5.7 2.8 31.0 0.0 0.0 0.2 0.0 125.8 0.0 1.1 0.0 166.6 0.0 0.0 204.7 0.0 9.2 0.0 0.0 0.1 0.1 0.0 6.3 0.1 0.6 0.8 2.2 0.2 0.0 0.4 0.5 2.2 5.9 0.2 0.0 0.4 56.0 0.0 0.1 0.2 JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 106.8;Endothelial cells: 30.3;Granulosa cells: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 29.3;HUVEC TERT2: 29.9;LHCN-M2: 24.9;TIME: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" 31.2 7.5 13.5 5.2 21.2 0.1 13.0 5.1 13.0 6.5 3.1 36.0 1.4 17.3 7.5 5.9 12.5 10.4 18.3 10.8 7.2 6.7 1.8 24.2 3.5 12.5 8.4 10.9 16.9 4.9 4.5 33.6 10.1 7.8 3.9 13.1 2.4 9.5 9.9 3.7 3.7 17.3 7.3 0.9 4.5 14.0 13.3 6.1 13.6 14.8 1.8 18.3 4.4 8.1 15.3 6.7 5.9 0.0 3.7 0.9 8.6 8.1 8.5 1.2 2.0 2.6 0.1 0.0 0.6 29.3 1.7 0.3 1.6 0.5 3.3 1.7 3.6 0.0 0.0 0.1 16.0 0.0 1.0 9.1 0.2 19.9 1.5 0.5 29.9 0.4 0.0 0.0 24.9 0.5 0.0 0.7 1.2 0.9 10.2 0.0 3.3 0.0 1.2 0.3 0.8 0.1 0.3 0.1 0.0 8.4 0.0 1.4 67.8 14.9 3.6 4.7 0.7 6.2 0.8 0.0 3.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 21.2 5.1 13.0 10.8 7.2 12.5 8.4 10.1 7.3 13.3 8.1 106.8 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 16.4 0.0 1.3 8.5 30.3 0.0 0.0 0.0 0.4 0.9 2.2 0.0 0.8 1.3 72.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 0.2 7.1 0.0 0.0 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 JSRP1 "FLJ32416, JP-45" ENSG00000167476 "Junctional sarcoplasmic reticulum protein 1" Q96MG2 19 2252252-2269759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skeletal muscle: 335.4" "Cell type enhanced" "Detected in many" "B-cells: 31.7;Melanocytes: 46.2;Plasma cells: 139.4;Skeletal myocytes: 132.6" "Cancer enriched" "Detected in many" 4 "endometrial cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "naive B-cell: 2.6" "Lineage enriched" "Detected in single" 10 "B-cells: 2.6" "Cell line enhanced" "Detected in some" "Karpas-707: 164.1;RPMI-8226: 109.8;U-266/70: 444.1;U-266/84: 57.8" "Group enriched" "Detected in many" 6 "amygdala: 8.4;basal ganglia: 11.6;cerebral cortex: 9.9;hippocampal formation: 4.4;white matter: 5.1" "Not detected" "Not detected" HPA044741 Enhanced Approved "Endoplasmic reticulum" NA NA 13000 "Cluster 24: B-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA044741: AB_10794295" "unprognostic (9.41e-3)" "unprognostic (1.52e-2)" "unprognostic (1.39e-1)" "unprognostic (5.85e-2)" "unprognostic (2.15e-1)" "unprognostic (9.69e-2)" "unprognostic (1.58e-2)" "unprognostic (4.64e-2)" "unprognostic (4.27e-2)" "unprognostic (1.80e-2)" "unprognostic (2.44e-2)" "unprognostic (1.87e-2)" "unprognostic (8.64e-5)" "unprognostic (3.63e-1)" "unprognostic (4.43e-1)" "unprognostic (2.07e-1)" "unprognostic (2.71e-1)" 0.2 0.1 0.4 0.9 0.4 0.4 0.4 0.4 0.4 0.3 0.2 1.5 2.9 0.1 0.0 0.3 0.3 0.1 0.0 0.3 0.4 0.6 0.3 0.7 0.5 0.3 0.3 0.1 0.5 0.0 0.3 0.0 0.3 1.9 0.1 0.0 8.9 0.0 335.4 0.3 1.4 0.0 0.3 5.4 1.7 1.9 0.5 0.1 0.6 18.6 0.6 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 26.8 0.0 0.0 0.2 0.0 0.0 0.0 46.6 0.1 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 7.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 26.7 109.8 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 444.1 57.8 2.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.4 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.5 0.3 0.1 0.0 5.3 0.0 31.7 0.5 0.3 0.2 0.6 0.8 0.6 0.4 0.6 1.5 0.1 0.0 2.1 0.2 0.7 1.7 0.0 1.8 19.0 0.7 0.3 0.3 5.4 1.3 0.2 1.0 0.6 1.1 1.5 1.1 6.3 2.9 0.7 0.6 0.5 0.0 0.1 2.3 2.0 1.3 2.2 18.2 0.6 1.1 46.2 0.0 0.0 0.5 1.0 0.0 0.1 1.0 0.3 0.0 139.4 0.3 0.6 0.4 1.7 0.5 0.0 132.6 0.6 7.6 1.9 0.2 1.0 0.3 5.0 0.5 0.7 0.2 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1434.2;Inhibitory neurons: 480.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "CACO-2: 57.4;HEL: 35.3;OE19: 20.1;SH-SY5Y: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 83000 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 9.4 6.3 15.0 2.2 23.4 0.3 6.7 0.0 31.3 9.1 4.9 2.0 2.5 7.7 1.9 9.5 4.6 2.9 12.8 21.3 3.4 3.8 5.8 4.4 0.9 0.0 6.6 3.1 8.8 3.5 4.1 4.2 0.0 2.8 1.8 4.5 2.8 4.9 27.2 2.0 2.0 6.2 0.0 8.5 12.1 2.6 10.7 0.5 5.1 19.3 1.6 2.6 6.0 20.9 0.7 1.1 6.2 1.3 0.9 0.2 8.1 2.5 1.5 2.4 1.1 57.4 4.5 0.2 0.8 6.4 3.9 0.4 1.4 0.0 2.0 0.0 0.7 35.3 0.4 8.9 0.1 0.0 0.0 0.4 0.0 0.5 0.1 2.6 2.9 0.1 8.3 0.2 0.7 4.2 0.0 0.0 3.5 20.1 5.4 1.8 2.8 0.0 0.2 0.5 2.1 15.9 0.7 0.5 0.5 6.0 1.2 0.1 14.4 7.0 2.8 1.0 1.1 0.0 0.6 0.0 0.8 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.7 0.2 0.2 0.0 0.0 0.0 1.6 0.4 15.0 23.4 0.0 31.3 21.3 3.4 0.0 6.6 0.0 0.0 10.7 20.9 56.2 3.2 3.9 191.3 0.6 1.7 1.5 0.3 0.6 61.2 6.1 7.1 32.1 18.6 0.5 16.5 6.2 8.0 2.5 40.5 1.9 5.0 57.0 15.0 18.8 23.2 9.6 5.3 1434.2 8.4 1.7 5.9 29.0 7.4 3.8 4.4 45.3 21.7 1.0 0.0 480.8 16.4 0.0 1.6 1.1 64.0 3.7 5.3 3.6 48.7 0.0 4.7 8.2 162.3 63.1 4.4 21.0 33.1 0.3 2.6 34.8 3.6 8.4 2.7 19.7 8.8 21.8 5.2 2.6 4.9 1.1 14.2 1.0 17.5 12.3 1.6 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KCNA4 "HK1, HPCN2, KCNA4L, Kv1.4" ENSG00000182255 "Potassium voltage-gated channel subfamily A member 4" P22459 11 30009730-30017030 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cataract, Disease variant, Dystonia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 6.1;brain: 20.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.7;Excitatory neurons: 8.2;Horizontal cells: 13.5;Muller glia cells: 6.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 20.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB001977, HPA016422" Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 62: Horizontal cells - Visual perception" "CAB001977: , HPA016422: AB_1855574" "unprognostic (1.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" "unprognostic (6.71e-2)" "unprognostic (1.17e-1)" 1.5 6.1 4.7 0.0 20.0 0.0 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 4.7 4.4 0.2 0.0 0.7 0.0 1.6 1.7 0.0 0.0 0.0 1.3 0.2 1.3 0.0 0.0 1.9 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 20.0 0.0 6.5 4.7 4.4 1.6 1.7 1.3 0.1 6.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 8.2 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.5 2.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.4 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.8;Excitatory neurons: 108.6;Inhibitory neurons: 605.4;Oligodendrocyte precursor cells: 206.6;Oligodendrocytes: 97.5;Sertoli cells: 78.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 3.4;hTEC/SVTERT24-B: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 15.8 6.3 12.7 1.2 52.7 1.6 7.3 15.5 17.3 8.4 4.2 4.1 1.7 5.4 12.8 2.2 4.3 2.9 5.5 25.9 11.6 1.8 2.6 3.3 0.9 7.2 12.1 2.9 4.0 2.0 1.8 1.3 7.2 22.4 1.8 12.8 3.9 19.2 2.0 2.2 2.7 2.7 8.4 5.2 1.6 3.1 14.1 1.8 28.7 5.1 0.3 2.9 5.0 15.4 0.5 0.5 0.7 0.2 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.9 0.1 0.4 0.7 0.0 0.3 0.3 0.0 0.0 0.0 0.4 1.0 3.4 0.6 1.6 0.0 1.0 0.2 0.0 0.0 5.2 0.0 1.1 2.1 0.5 0.1 0.3 0.2 0.1 0.3 0.6 1.1 1.5 0.2 0.6 0.7 2.8 0.0 0.2 0.8 0.8 0.3 0.6 0.7 0.5 0.8 0.5 2.2 0.8 0.5 1.4 1.2 1.8 0.4 0.4 2.6 1.1 1.0 0.8 0.1 0.0 0.4 0.2 0.8 0.2 0.4 0.3 0.2 0.2 0.3 0.3 0.0 0.3 0.3 1.2 0.5 0.1 12.7 52.7 15.5 17.3 25.9 11.6 7.2 12.1 7.2 8.4 14.1 15.4 7.2 0.0 0.0 7.5 0.7 0.8 0.3 0.0 0.0 85.8 1.4 1.4 4.3 0.0 0.7 0.0 31.3 0.1 0.5 0.1 0.0 0.4 13.7 0.6 2.4 2.8 0.0 0.0 108.6 0.0 0.0 3.8 0.0 2.1 0.0 0.4 0.7 0.0 4.6 0.0 605.4 0.0 0.0 11.1 1.0 7.0 0.0 1.2 1.8 24.4 0.0 2.7 0.0 206.6 97.5 0.0 0.0 2.6 2.3 0.2 0.0 0.1 0.0 6.7 78.9 1.3 73.3 0.3 4.2 1.2 0.9 0.1 0.5 0.2 0.0 0.2 KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5990927-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 188.3" "Cell type enhanced" "Detected in many" "dendritic cells: 50.3;Excitatory neurons: 67.8;Hofbauer cells: 63.6;Inhibitory neurons: 49.2;Kupffer cells: 86.2;Macrophages: 51.3;Melanocytes: 64.0;NK-cells: 51.5" "Cancer enriched" "Detected in all" 7 "melanoma: 29.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 278.8;JURKAT: 142.7;U-937: 289.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB001975: " "unprognostic (6.60e-2)" "unprognostic (2.33e-2)" "unprognostic (3.97e-3)" "unprognostic (2.30e-2)" "unprognostic (1.76e-2)" "unprognostic (8.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-2)" "unprognostic (7.71e-3)" "unprognostic (8.83e-3)" "prognostic unfavorable (3.50e-5)" "unprognostic (2.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" 12.8 7.7 69.2 28.6 94.1 63.8 8.0 7.4 188.3 5.6 0.0 8.8 5.4 7.2 2.3 5.0 8.6 11.2 22.1 141.6 12.8 26.0 10.1 31.1 43.6 78.7 5.3 5.6 4.0 1.5 20.3 5.9 77.5 6.2 4.6 17.8 6.4 3.4 12.6 12.3 23.9 6.3 1.5 65.8 6.5 5.6 18.9 27.0 6.2 15.8 24.7 8.8 5.1 89.7 11.3 27.0 2.5 4.5 1.5 5.0 10.3 6.3 40.0 6.3 7.8 10.6 4.1 62.0 23.3 6.1 7.7 5.4 2.7 1.0 3.2 84.6 9.6 71.1 25.3 21.1 6.0 278.8 1.9 6.5 1.3 3.4 7.5 6.3 3.6 142.7 2.7 114.2 3.1 9.8 61.9 115.9 1.1 3.9 15.4 13.8 9.7 78.9 0.1 0.2 20.6 6.2 5.3 6.4 101.0 2.7 5.4 117.3 1.1 1.3 9.4 14.4 7.5 84.4 122.4 100.4 12.7 289.2 1.9 4.4 34.3 18.6 29.8 27.2 26.8 7.5 18.2 28.0 31.0 8.7 18.7 20.6 14.4 19.4 25.0 12.7 19.1 43.2 69.2 94.1 7.4 188.3 141.6 12.8 78.7 5.3 77.5 1.5 18.9 89.7 3.0 0.0 6.6 7.5 23.0 4.8 1.7 1.8 1.8 24.0 1.2 2.3 15.7 7.2 1.5 1.8 6.2 0.5 50.3 0.3 0.0 0.3 5.8 3.4 1.9 3.1 0.0 11.1 67.8 1.4 2.3 3.5 2.0 0.6 8.8 2.9 3.9 1.0 63.6 6.7 49.2 0.5 2.0 86.2 19.0 5.2 3.7 51.3 64.0 5.6 26.6 4.9 51.5 8.5 6.1 0.6 0.1 2.6 23.4 0.4 0.1 40.8 8.7 11.8 0.0 2.1 3.1 3.2 2.9 0.7 2.8 0.8 44.3 2.5 0.3 0.6 KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "retina: 113.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 115.6;Cone photoreceptor cells: 212.7;Excitatory neurons: 150.6;Inhibitory neurons: 89.9;Rod photoreceptor cells: 386.9" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Region enhanced" "Detected in many" "cerebral cortex: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.4;CACO-2: 2.2;HL-60: 1.1;hTCEpi: 1.2;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001979, HPA042434" Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB001979: , HPA042434: AB_2677996" "unprognostic (4.51e-1)" "unprognostic (1.72e-1)" "unprognostic (6.54e-3)" "unprognostic (4.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (8.09e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-1)" "unprognostic (8.32e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-4)" 10.7 1.5 4.3 0.3 6.6 0.0 2.8 0.0 17.8 1.2 0.0 6.2 0.2 7.3 0.8 1.7 6.0 0.6 1.2 6.6 0.0 0.3 2.4 0.3 0.0 0.0 0.0 0.4 0.3 0.2 2.7 0.1 0.0 2.2 0.6 113.3 1.6 3.1 7.3 0.5 2.0 5.0 0.0 0.3 3.4 0.4 0.0 0.1 0.1 4.4 0.0 3.8 0.9 7.9 0.0 0.0 0.3 0.0 1.4 0.1 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.2 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.9 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.9 0.7 0.6 0.9 0.0 0.0 0.7 0.0 0.0 0.9 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 6.6 0.0 17.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 7.9 20.2 0.0 2.2 7.8 0.5 0.8 0.2 0.0 0.0 115.6 0.9 0.5 3.4 1.5 0.7 0.0 212.7 0.0 0.4 0.0 0.0 0.0 0.7 19.8 2.9 8.0 0.0 0.0 150.6 0.0 0.0 1.4 0.0 4.2 3.8 1.5 0.0 5.7 0.1 18.5 89.9 0.0 0.0 0.0 0.3 0.8 4.4 0.4 0.0 12.2 0.0 38.2 0.0 43.2 3.3 0.1 0.0 34.6 0.1 0.1 0.0 0.2 4.0 386.9 0.0 0.9 7.0 0.2 0.5 0.2 0.3 0.1 0.4 0.2 0.0 0.1 KCNE5 KCNE1L ENSG00000176076 "Potassium voltage-gated channel subfamily E regulatory subunit 5" Q9UJ90 X 109623700-109625172 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Alport syndrome, Deafness, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.8;skeletal muscle: 4.0;tongue: 4.9" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Erythroid cells: 3.8;monocytes: 9.4;Muller glia cells: 5.3;Peritubular cells: 3.8" "Group enriched" "Detected in some" 8 "glioma: 7.9;testis cancer: 2.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;hTEC/SVTERT24-B: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042316 Uncertain Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA042316: AB_10795397" "unprognostic (5.33e-2)" "unprognostic (2.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-3)" "unprognostic (3.27e-2)" "unprognostic (9.46e-2)" "unprognostic (1.05e-1)" "unprognostic (4.62e-3)" "unprognostic (7.83e-2)" "unprognostic (5.64e-6)" "unprognostic (5.10e-2)" "unprognostic (9.06e-2)" "unprognostic (1.36e-1)" "unprognostic (5.37e-3)" 1.1 0.8 3.2 0.1 5.4 1.6 0.5 9.4 2.7 0.2 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.7 2.7 6.6 0.7 0.2 0.4 0.0 6.3 9.8 0.5 0.1 0.0 0.3 0.2 6.9 0.3 0.0 0.2 0.2 0.3 4.0 0.1 0.1 0.1 4.0 0.9 0.1 0.3 7.8 2.3 0.1 4.9 0.0 0.3 0.2 4.6 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.3 0.3 0.0 0.8 0.3 0.0 0.1 1.0 1.1 0.7 0.0 0.0 1.5 0.2 0.5 2.0 0.5 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.4 0.5 0.0 0.9 0.4 0.7 0.3 0.3 0.9 0.2 0.2 0.1 0.4 0.4 0.1 0.0 0.3 0.0 0.3 0.8 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 3.2 5.4 9.4 2.7 2.7 6.6 6.3 9.8 6.9 4.0 7.8 4.6 0.1 0.0 1.1 4.6 0.1 0.0 0.0 0.0 1.2 0.0 0.3 1.1 0.6 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.3 0.0 0.5 0.1 0.2 0.0 3.8 0.1 0.4 1.2 1.4 0.0 0.5 1.3 0.7 1.1 0.0 0.6 0.0 0.1 0.0 0.0 2.0 0.0 0.0 1.2 2.1 0.0 1.0 9.4 5.3 0.0 0.0 0.0 0.3 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.1 0.0 0.8 0.2 0.1 0.0 0.1 KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 28.9;choroid plexus: 32.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.3;Extravillous trophoblasts: 14.4;Inhibitory neurons: 8.8;Oligodendrocyte precursor cells: 18.1;Syncytiotrophoblasts: 7.7" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 14.3;MCF7: 5.1;T-47d: 6.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA014738: AB_1852114, HPA062278: AB_2732679" "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" 0.1 0.0 20.6 0.1 28.9 0.0 0.2 0.0 21.5 0.0 32.1 1.2 0.2 0.6 0.0 0.2 0.1 0.1 0.7 28.8 14.7 0.4 0.0 0.3 0.1 0.0 5.3 0.0 0.9 0.3 0.8 0.0 0.0 0.7 0.2 0.2 0.1 0.3 0.0 0.0 0.6 0.0 0.6 0.5 0.3 0.5 12.5 0.3 0.0 0.0 0.0 0.6 0.0 15.8 0.1 14.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 2.1 0.1 1.5 0.0 0.1 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.1 6.1 0.7 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 28.9 0.0 21.5 28.8 14.7 0.0 5.3 0.0 0.6 12.5 15.8 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.2 0.0 2.0 0.8 1.4 1.4 0.0 0.0 0.0 2.1 0.0 0.1 1.6 0.0 0.0 2.2 0.8 0.3 0.9 1.2 0.0 9.3 0.0 14.4 0.7 0.0 2.0 0.0 0.2 0.0 0.0 0.2 0.0 8.8 0.2 0.0 0.0 0.0 3.4 0.3 0.1 0.0 1.9 0.0 0.3 0.0 18.1 1.4 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 7.7 0.0 0.4 0.3 0.1 KCNIP2 KCHIP2 ENSG00000120049 "Potassium voltage-gated channel interacting protein 2" Q9NS61 10 101825974-101843920 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4;brain: 139.6;heart muscle: 307.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.3;Cardiomyocytes: 135.7;Cone photoreceptor cells: 25.0;Excitatory neurons: 23.3;Horizontal cells: 48.8;Inhibitory neurons: 41.9" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 12.7" "Group enriched" "Detected in all" 4 "amygdala: 96.8;basal ganglia: 234.9;cerebral cortex: 106.9;hippocampal formation: 142.6;olfactory bulb: 144.0" "Low region specificity" "Detected in all" HPA066717 Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA066717: " "unprognostic (5.92e-2)" "unprognostic (2.16e-1)" "unprognostic (3.48e-3)" "unprognostic (5.77e-4)" "unprognostic (1.34e-1)" "unprognostic (1.31e-3)" "unprognostic (8.80e-2)" "unprognostic (9.11e-3)" "unprognostic (1.14e-1)" "unprognostic (5.34e-2)" "unprognostic (3.18e-2)" "unprognostic (7.20e-2)" "unprognostic (1.49e-9)" "unprognostic (9.85e-2)" "unprognostic (1.81e-1)" "unprognostic (3.27e-1)" "unprognostic (8.37e-4)" 227.4 6.8 74.5 3.5 139.6 0.9 67.1 48.8 84.5 7.4 40.5 5.0 1.8 4.1 4.1 2.5 4.9 3.1 307.5 98.8 50.6 2.8 2.3 2.5 8.1 47.5 51.6 11.5 2.4 1.7 19.7 2.9 48.1 5.2 4.7 52.6 9.9 3.5 8.0 5.9 5.3 2.6 50.3 5.7 2.7 8.5 57.1 2.3 3.5 5.4 8.3 4.8 4.4 60.8 1.7 2.6 2.5 3.2 1.0 1.1 0.6 1.2 1.0 0.6 0.9 3.6 3.4 1.6 0.9 0.8 0.7 1.7 0.9 0.4 0.6 2.4 2.0 21.3 3.0 1.9 0.9 1.4 12.7 2.6 1.7 1.0 1.4 3.7 1.0 4.7 6.3 1.8 1.0 1.2 0.8 4.0 0.8 0.7 0.6 1.0 0.2 1.4 1.0 1.1 7.4 1.2 0.8 0.6 2.4 1.5 2.2 0.9 2.3 1.3 2.0 0.6 1.2 1.7 1.9 1.7 1.4 5.3 0.2 0.0 0.0 0.7 0.0 0.5 0.1 0.9 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 74.5 139.6 48.8 84.5 98.8 50.6 47.5 51.6 48.1 50.3 57.1 60.8 0.4 0.0 0.0 8.5 2.3 0.4 0.1 0.3 0.0 54.3 0.3 0.5 135.7 0.0 0.1 1.8 25.0 0.2 0.0 0.8 0.0 0.2 6.6 0.0 0.2 1.6 0.0 0.0 23.3 0.0 0.2 5.8 0.0 0.0 0.0 0.8 0.4 0.1 2.2 48.8 41.9 0.4 0.0 0.6 0.8 5.2 1.8 0.3 0.0 1.0 0.5 8.3 0.0 5.5 3.7 0.3 0.2 0.7 0.3 0.1 0.5 0.1 0.2 4.7 0.0 0.1 1.3 2.5 5.5 0.5 0.0 0.3 0.1 0.5 0.3 0.1 KCNJ12 "hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v" ENSG00000184185 "Potassium inwardly rectifying channel subfamily J member 12" Q14500 17 21376357-21419870 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 25.5;skeletal muscle: 69.1;tongue: 25.7" "Cell type enriched" "Detected in many" 6 "Horizontal cells: 89.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.3;HeLa: 3.9;PC-3: 4.3;SCLC-21H: 4.8;SiHa: 2.5;SuSa: 5.2;U-2197: 4.2" HPA027021 Approved Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: AB_10602912" "unprognostic (3.81e-3)" "unprognostic (2.69e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (4.91e-2)" "unprognostic (8.12e-2)" "unprognostic (1.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-1)" "unprognostic (5.90e-2)" "unprognostic (9.70e-3)" 1.3 1.1 2.9 0.6 2.2 0.4 0.8 25.5 3.3 1.2 0.0 0.9 0.1 0.5 0.6 1.4 2.1 0.4 6.4 1.5 2.9 1.3 0.1 1.9 0.1 4.0 6.0 0.4 0.2 5.5 0.8 0.4 3.1 0.6 0.3 1.3 0.7 0.6 69.1 3.6 0.4 0.6 1.1 1.2 1.1 0.8 10.8 0.1 1.1 25.7 1.0 0.7 0.5 1.4 0.0 0.7 0.3 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.0 0.0 4.3 0.0 0.6 1.1 0.0 0.0 4.8 0.2 2.5 0.0 1.1 5.2 0.0 0.0 2.0 0.0 0.3 4.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.2 25.5 3.3 1.5 2.9 4.0 6.0 3.1 1.1 10.8 1.4 1.4 0.0 0.0 0.7 0.0 1.5 0.0 2.3 0.0 2.9 0.0 0.3 14.3 0.0 1.2 1.8 0.0 0.0 0.1 1.1 1.9 0.0 0.5 0.4 0.5 3.4 1.2 0.0 2.8 0.0 0.0 3.4 0.5 1.8 0.0 0.0 6.8 0.1 0.2 89.2 5.7 1.4 4.1 0.0 1.2 0.5 7.5 0.1 0.0 2.8 0.0 10.2 0.0 0.0 0.2 0.0 0.5 4.1 0.0 0.2 0.0 0.8 0.1 1.5 0.0 3.0 0.7 0.6 2.5 0.0 2.3 0.1 0.5 0.0 1.8 0.2 KCNJ8 Kir6.1 ENSG00000121361 "Potassium inwardly rectifying channel subfamily J member 8" Q15842 12 21764955-21775600 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 71.3" "Group enriched" "Detected in many" 4 "Sertoli cells: 197.2;Smooth muscle cells: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cell line enhanced" "Detected in some" "BJ: 11.1;CACO-2: 58.4;SH-SY5Y: 30.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031066 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA031066: AB_10602240" "unprognostic (8.12e-3)" "unprognostic (1.89e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.81e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-2)" "unprognostic (3.90e-2)" "unprognostic (3.66e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (4.70e-3)" "unprognostic (9.61e-2)" "unprognostic (1.73e-2)" "unprognostic (3.54e-3)" 28.6 17.3 4.9 3.2 5.4 0.0 22.1 4.8 5.7 17.0 11.6 15.6 1.2 18.8 0.7 3.6 14.8 1.8 71.3 4.7 5.0 13.9 41.9 13.8 2.5 5.2 5.3 16.8 42.4 1.8 7.8 3.0 5.1 13.0 0.3 0.8 6.4 8.4 17.1 5.8 5.9 5.5 5.2 8.0 12.7 1.0 7.2 0.6 16.1 4.5 0.4 15.1 11.5 4.7 0.0 0.1 0.9 0.0 1.4 3.2 0.0 11.1 4.4 6.5 1.9 58.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.1 0.0 4.3 2.9 0.0 0.0 0.0 0.0 0.0 4.5 0.0 3.2 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.6 2.7 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.4 4.8 5.7 4.7 5.0 5.2 5.3 5.1 5.2 7.2 4.7 18.7 3.2 29.5 2.9 0.0 1.3 0.4 0.0 0.6 0.0 9.2 3.0 28.3 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.7 10.8 12.8 1.2 0.0 3.6 1.3 0.0 9.8 0.0 0.9 0.0 1.0 2.9 23.0 0.3 0.0 0.2 0.0 0.0 0.8 1.5 0.1 0.3 0.3 1.8 0.0 0.0 13.2 0.0 0.5 0.4 1.2 0.0 0.7 0.1 0.4 0.0 0.0 0.0 2.0 197.2 3.3 61.6 0.0 1.0 0.1 0.9 0.3 0.3 0.5 0.2 0.6 KCNK3 "K2p3.1, TASK, TASK-1, TASK1" ENSG00000171303 "Potassium two pore domain channel subfamily K member 3" O14649 2 26692690-26733420 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 181.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.1;Collecting duct cells: 103.0;Enteroendocrine cells: 23.4;Exocrine glandular cells: 95.2" "Cancer enhanced" "Detected in many" "renal cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.1;EFO-21: 11.0;HeLa: 3.6;SCLC-21H: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (4.16e-3)" "unprognostic (7.13e-2)" "unprognostic (1.04e-1)" "unprognostic (1.67e-4)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (5.01e-2)" "unprognostic (2.16e-1)" "unprognostic (3.31e-1)" "unprognostic (5.48e-2)" "unprognostic (3.77e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.37e-7)" "unprognostic (3.09e-2)" "unprognostic (7.45e-2)" "unprognostic (1.44e-2)" "unprognostic (9.24e-3)" 3.8 181.6 5.1 1.3 4.4 0.1 2.9 4.9 6.0 8.4 0.0 5.5 1.2 6.3 1.5 2.1 4.0 1.2 13.1 3.0 14.3 2.7 0.5 25.7 0.1 27.0 19.3 2.1 35.5 12.1 8.4 24.8 26.8 6.3 0.9 3.3 0.4 3.3 0.8 0.7 2.4 2.7 5.4 1.1 4.2 0.6 10.4 0.1 3.6 0.0 0.0 4.2 2.8 3.9 0.0 0.7 0.2 0.0 5.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 11.0 0.0 1.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.4 0.0 25.9 2.3 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 5.1 4.4 4.9 6.0 3.0 14.3 27.0 19.3 26.8 5.4 10.4 3.9 0.3 0.0 2.8 0.3 0.1 0.0 0.2 0.3 0.0 82.1 0.2 3.6 12.7 0.0 0.0 103.0 0.0 0.2 0.1 0.0 0.0 1.0 0.4 0.3 7.7 1.2 23.4 0.0 2.1 95.2 0.2 2.7 0.0 0.2 0.0 1.2 0.4 0.0 0.4 1.7 14.5 1.8 0.0 0.0 0.9 1.9 0.9 0.3 0.0 0.0 0.6 1.4 0.0 1.5 0.3 19.2 0.0 0.0 0.3 1.6 0.1 0.1 0.0 4.1 6.6 0.6 4.9 0.0 1.5 0.0 0.1 0.5 0.4 11.5 0.1 0.4 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 281.2;Endothelial cells: 192.2;Enteroendocrine cells: 386.7;Hofbauer cells: 218.9;Kupffer cells: 395.9;Macrophages: 221.3;monocytes: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cell line enhanced" "Detected in many" "ASC diff: 111.4;HUVEC TERT2: 229.0;TIME: 186.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" 76.1 27.8 21.4 55.7 20.1 12.0 52.4 27.0 20.8 44.5 12.4 39.5 22.5 51.3 17.8 38.3 75.0 55.0 22.6 26.9 27.8 31.0 13.9 58.0 39.4 36.2 33.5 47.1 12.5 25.2 6.4 83.9 31.4 14.7 42.5 3.4 20.0 18.5 16.6 22.9 28.1 65.3 37.0 64.8 28.0 26.9 31.4 18.3 16.4 37.1 33.4 39.2 17.4 34.4 1.7 1.5 15.3 0.0 111.4 52.5 4.3 6.9 1.5 4.2 5.5 0.5 0.3 0.0 3.8 18.8 4.9 53.9 6.6 66.4 3.5 1.5 35.1 0.2 38.3 0.0 4.7 18.6 0.1 21.4 21.5 2.7 48.9 8.5 229.0 13.2 0.3 0.2 53.9 1.4 8.5 0.3 7.8 16.6 7.7 0.4 7.4 19.6 17.7 0.2 4.3 7.9 17.3 0.5 2.2 18.5 1.0 12.1 186.0 2.7 4.9 0.4 14.0 2.7 0.5 0.0 42.5 4.0 16.1 0.0 3.9 0.7 0.0 2.5 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.0 0.0 1.5 1.9 0.0 0.9 21.4 20.1 27.0 20.8 26.9 27.8 36.2 33.5 31.4 37.0 31.4 34.4 281.2 25.6 8.4 2.9 7.5 40.0 2.7 11.9 28.5 4.4 11.2 27.3 21.8 4.3 16.3 97.5 14.6 3.0 30.4 19.7 17.6 6.5 3.6 4.9 44.6 192.2 386.7 6.1 4.8 0.6 90.6 80.0 12.2 3.3 7.0 53.1 61.1 2.5 218.9 0.0 11.5 71.5 12.2 395.9 75.4 11.8 157.2 221.3 51.6 45.9 206.7 4.8 7.2 0.5 0.9 0.5 15.7 44.8 7.6 4.5 0.7 7.5 72.8 1.5 26.3 153.2 32.2 1.9 7.0 16.9 34.4 4.2 5.5 24.0 46.6 1.9 KCTD21 KCASH2 ENSG00000188997 "Potassium channel tetramerization domain containing 21" Q4G0X4 11 78171249-78188626 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041964 Uncertain Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041964: AB_10795647" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (3.74e-3)" "unprognostic (6.40e-3)" "unprognostic (8.06e-2)" "unprognostic (2.48e-2)" "unprognostic (1.52e-1)" "unprognostic (6.82e-2)" "unprognostic (8.85e-2)" "unprognostic (1.37e-3)" "unprognostic (2.49e-1)" "unprognostic (1.31e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "unprognostic (4.70e-1)" "prognostic favorable (9.57e-5)" "unprognostic (3.43e-2)" 7.3 13.4 14.4 6.2 13.6 3.5 4.4 13.1 14.3 5.8 8.7 6.5 5.0 5.0 9.2 9.6 6.2 7.9 6.3 13.7 14.3 5.5 15.9 6.7 5.4 14.7 16.3 13.7 3.5 5.7 5.9 7.7 15.0 4.2 4.8 4.3 5.8 5.2 8.5 4.9 4.5 7.1 12.4 4.6 4.5 4.0 14.6 5.9 11.2 7.0 6.2 7.1 5.9 14.7 5.2 11.8 6.7 5.0 23.8 16.9 4.1 10.1 9.6 7.1 7.1 11.1 7.8 5.0 9.9 11.4 9.5 10.1 6.5 8.4 7.3 6.9 3.9 3.8 15.4 9.8 13.2 2.4 4.7 16.4 15.4 15.5 8.8 14.8 11.0 6.1 8.1 4.5 9.7 7.3 3.8 7.3 3.0 19.0 8.9 5.0 5.1 3.1 8.3 9.3 4.6 7.1 6.4 4.6 4.9 12.1 10.6 2.6 12.9 11.3 11.0 30.0 3.9 8.6 9.2 4.8 5.9 3.9 6.4 2.0 5.4 7.5 0.9 6.0 1.4 0.6 1.4 1.7 3.7 1.4 1.3 1.0 8.3 1.4 5.1 0.8 1.1 2.2 14.4 13.6 13.1 14.3 13.7 14.3 14.7 16.3 15.0 12.4 14.6 14.7 1.9 0.0 2.7 4.6 0.7 1.8 1.2 1.5 0.6 1.7 2.4 2.2 3.5 5.7 2.0 0.0 0.0 1.2 0.6 2.8 1.9 1.5 0.3 1.4 2.5 2.3 0.0 0.0 4.1 2.2 1.1 2.8 1.1 1.9 5.7 7.0 3.6 7.4 2.3 6.7 3.4 1.3 0.0 3.1 1.1 0.5 4.4 1.3 1.8 4.7 2.8 1.0 0.0 4.0 4.2 2.5 1.7 9.1 1.0 1.9 2.3 2.7 1.1 0.9 0.0 1.2 2.9 1.5 2.7 3.6 1.4 1.9 1.8 3.8 1.7 2.1 KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.6;Ductal cells: 29.4;Syncytiotrophoblasts: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Cell line enhanced" "Detected in some" "A-431: 24.9;BEWO: 20.8;CAPAN-2: 22.7;HaCaT: 21.4;HBEC3-KT: 30.3;hTCEpi: 38.5;OE19: 39.3;SK-BR-3: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Cytosol "HPA028634: , HPA028639: AB_10599191" "unprognostic (2.58e-1)" "unprognostic (1.23e-1)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.45e-2)" "unprognostic (9.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.73e-1)" "unprognostic (3.91e-1)" "prognostic favorable (3.04e-13)" "unprognostic (1.38e-3)" "unprognostic (7.83e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.40e-4)" 0.1 1.1 0.4 1.3 0.3 0.1 10.3 1.6 1.3 4.0 0.3 8.9 12.4 0.9 19.7 20.2 7.4 2.9 0.4 0.4 0.2 11.0 4.7 4.4 0.8 0.3 0.3 0.1 16.2 12.5 10.4 3.9 0.4 7.2 7.1 1.3 12.8 4.6 0.0 17.7 10.5 0.3 0.2 0.6 10.6 2.6 0.3 2.3 10.0 0.0 3.4 4.8 8.3 0.7 24.9 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 12.1 22.7 0.0 0.9 0.0 0.0 21.4 0.0 30.3 0.0 0.1 0.4 0.0 0.0 4.4 0.3 0.0 0.0 0.1 38.5 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.0 14.7 0.0 0.1 1.7 39.3 0.1 0.0 0.0 3.7 5.5 11.7 14.9 0.0 0.2 25.2 0.1 2.7 16.1 0.4 0.2 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.2 2.5 4.3 3.0 0.1 3.4 6.2 3.8 0.0 0.0 0.0 0.0 0.2 1.7 0.4 0.3 1.6 1.3 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.7 0.2 12.8 8.8 0.0 0.8 0.0 14.3 0.0 10.8 0.6 15.1 16.3 0.3 12.8 2.5 14.7 0.0 32.6 1.5 17.2 25.4 29.4 0.4 7.3 0.8 0.7 7.8 0.0 0.2 23.2 26.5 0.6 13.7 8.0 0.0 0.1 0.0 4.4 2.7 0.0 0.1 13.1 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.0 0.2 1.1 0.0 0.0 0.1 21.8 25.2 0.0 0.4 16.8 26.2 10.1 5.1 2.5 0.0 0.0 0.3 6.3 7.5 14.4 0.0 29.7 1.2 0.0 16.9 19.0 KDM4B "JMJD2B, KIAA0876, TDRD14B" ENSG00000127663 "Lysine demethylase 4B" O94953 19 4969113-5153598 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 98.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 5.1;dendritic cells: 1.7;granulocytes: 4.7" "Cell line enhanced" "Detected in all" "T-47d: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071568 Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA071568: " "prognostic favorable (7.39e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.74e-4)" "prognostic favorable (4.25e-7)" "unprognostic (5.95e-2)" "unprognostic (7.96e-3)" "unprognostic (2.72e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.89e-2)" "unprognostic (8.24e-3)" "unprognostic (5.14e-3)" "unprognostic (8.66e-2)" "unprognostic (1.98e-1)" "unprognostic (3.82e-1)" "unprognostic (4.14e-2)" "unprognostic (5.44e-2)" 12.4 19.4 7.8 8.9 9.4 13.5 16.8 15.8 10.0 23.4 5.1 14.7 6.6 18.4 6.7 17.0 20.2 4.7 16.0 9.3 5.3 10.4 21.2 12.5 11.7 9.2 7.3 17.8 13.7 6.6 18.4 9.5 7.5 25.6 2.9 14.7 14.1 7.4 32.2 21.7 13.8 4.9 4.7 22.1 12.6 16.1 8.8 8.8 29.4 8.3 7.2 13.4 18.2 11.9 16.1 5.5 12.8 15.4 7.3 7.2 25.7 7.9 5.8 6.8 8.5 9.6 4.4 22.4 8.2 9.1 5.5 8.9 7.8 9.3 4.2 10.1 19.9 7.5 9.9 8.0 13.6 7.6 16.7 11.2 9.9 5.6 4.7 12.3 9.3 12.4 18.7 13.3 6.2 8.3 8.8 11.5 11.3 5.8 13.6 14.7 9.7 19.0 6.8 10.5 23.7 18.1 10.3 11.2 12.5 12.3 61.5 19.7 13.5 10.1 5.7 12.5 8.0 36.5 16.4 17.1 20.0 15.1 6.0 1.5 0.6 1.9 0.3 0.2 0.2 4.2 0.2 0.2 0.3 5.1 0.4 0.5 4.7 0.8 0.3 1.7 0.4 0.3 7.8 9.4 15.8 10.0 9.3 5.3 9.2 7.3 7.5 4.7 8.8 11.9 15.3 6.4 10.4 18.9 73.2 7.4 14.1 10.8 7.4 72.5 36.1 22.2 15.3 10.0 9.4 7.3 98.0 25.7 25.5 15.3 7.9 10.5 17.0 25.4 18.7 16.4 8.4 9.4 33.6 7.6 26.2 14.6 26.5 30.2 8.2 34.3 15.4 30.9 9.0 74.0 30.6 16.7 16.2 14.2 7.8 12.1 18.3 15.8 10.6 27.2 17.0 23.5 19.6 29.7 28.7 18.0 14.1 23.3 23.9 19.3 7.4 6.6 11.7 69.2 6.6 23.1 13.7 25.2 9.1 14.1 15.3 24.1 13.9 29.7 9.5 12.9 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 211.9" "Cell type enhanced" "Detected in many" "Astrocytes: 132.2;Excitatory neurons: 139.6;Oligodendrocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.3;plasmacytoid DC: 10.0" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.3" "Cell line enhanced" "Detected in many" "THP-1: 327.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: AB_10675627" "unprognostic (4.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "prognostic favorable (9.22e-5)" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (6.90e-8)" "unprognostic (2.80e-1)" "unprognostic (2.03e-1)" "unprognostic (3.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (8.95e-7)" "unprognostic (6.89e-3)" "unprognostic (5.32e-2)" "unprognostic (5.58e-2)" "unprognostic (1.15e-1)" 33.9 58.3 195.7 27.7 209.3 24.7 25.9 163.3 211.9 46.0 130.3 29.4 14.6 24.0 40.4 34.5 18.2 16.0 18.1 184.1 189.1 23.8 48.4 24.8 29.0 182.8 192.6 13.6 20.1 18.5 19.2 12.0 179.8 29.1 11.2 3.5 26.7 24.7 33.8 64.0 21.4 15.2 170.4 38.7 18.6 26.2 193.6 20.4 18.4 13.1 22.3 44.0 35.6 210.3 49.6 31.5 19.1 38.3 64.1 30.2 19.2 26.9 26.8 28.2 24.1 29.5 26.5 33.2 39.2 42.8 22.5 54.5 29.5 118.6 10.7 35.6 46.4 0.1 42.0 34.3 25.7 89.4 19.7 17.1 59.2 27.3 45.3 21.5 26.8 23.9 11.7 53.1 17.4 56.9 40.0 82.8 18.9 35.8 26.5 48.1 12.9 110.7 42.6 29.7 15.9 28.4 42.5 57.6 75.5 36.8 28.1 327.8 36.5 29.0 50.6 39.7 15.7 44.9 32.9 32.1 34.0 133.7 30.3 0.8 11.0 8.6 2.3 13.9 1.6 2.3 0.9 2.6 12.1 1.8 0.9 1.6 2.5 1.9 17.3 10.0 2.0 3.7 195.7 209.3 163.3 211.9 184.1 189.1 182.8 192.6 179.8 170.4 193.6 210.3 11.4 6.4 8.8 132.2 9.9 52.8 18.6 22.7 6.8 7.3 13.9 13.5 11.5 12.8 11.8 18.4 6.2 2.0 24.9 16.2 0.0 18.6 2.9 11.6 9.3 9.7 10.7 23.1 139.6 20.7 6.5 32.7 4.6 19.5 2.5 3.8 17.5 23.3 67.5 5.0 56.7 10.0 14.2 71.1 50.0 10.8 10.8 59.8 44.4 24.4 68.5 6.5 13.4 16.1 152.9 18.0 13.7 14.7 11.2 25.6 15.7 13.8 9.3 5.9 0.0 10.2 10.9 7.5 4.4 15.2 57.3 2.7 9.3 5.3 12.8 23.1 KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.7;hTCEpi: 103.0;RT4: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" 7.9 93.0 14.6 7.0 10.7 1.2 24.3 1.8 15.6 14.5 27.1 42.5 51.7 10.1 12.2 76.7 23.5 16.0 5.1 12.4 6.5 43.9 12.0 18.2 1.2 5.2 5.5 22.3 70.7 37.8 9.1 8.4 4.3 40.9 30.9 1.2 68.3 20.2 3.1 74.1 45.9 6.7 4.2 1.4 61.8 5.1 7.7 8.2 39.4 3.2 12.1 22.2 28.1 8.8 65.7 33.6 5.4 9.3 2.4 4.6 24.6 7.9 15.3 8.9 8.7 37.0 125.7 0.2 32.3 11.6 26.5 95.1 10.3 67.8 4.6 0.2 13.4 13.6 49.4 30.4 4.0 0.2 33.3 1.7 103.0 23.6 28.2 40.1 18.6 2.7 20.1 0.4 4.3 54.3 0.3 0.6 11.0 56.3 20.9 8.7 6.7 16.7 85.8 117.5 4.6 4.7 49.5 70.1 9.7 33.7 74.7 4.3 17.6 14.9 39.3 13.7 17.3 0.8 0.3 0.3 15.2 2.3 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 10.7 1.8 15.6 12.4 6.5 5.2 5.5 4.3 4.2 7.7 8.8 5.7 12.8 56.9 5.5 0.6 73.9 37.0 52.7 59.2 0.6 69.8 42.3 3.8 72.9 52.0 27.6 2.1 15.6 1.5 154.4 9.8 47.3 4.2 54.7 5.6 8.7 28.9 1.3 10.2 66.7 5.2 6.7 51.0 50.2 27.8 10.2 4.6 10.6 2.9 0.0 5.2 54.0 48.8 0.8 6.5 5.1 8.7 2.2 7.2 3.7 2.4 0.8 0.0 2.0 0.4 60.7 64.6 4.9 0.3 80.9 84.7 14.8 60.7 0.1 6.6 3.1 7.5 3.8 2.7 59.7 83.1 7.9 2.1 59.9 65.4 99.6 KIF12 ENSG00000136883 "Kinesin family member 12" Q96FN5 9 114086126-114099291 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 162.3;pancreas: 85.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 105.8;Collecting duct cells: 90.1;Distal tubular cells: 80.3;Ductal cells: 43.3;Enteroendocrine cells: 64.1;Proximal enterocytes: 60.3;Proximal tubular cells: 79.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.6;OE19: 17.2;RPTEC TERT1: 44.8;SCLC-21H: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020192, HPA024127" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus, Plasma membrane" "HPA020192: AB_1852467, HPA024127: AB_1852469" "unprognostic (5.29e-2)" "unprognostic (5.03e-2)" "unprognostic (3.34e-1)" "unprognostic (1.84e-2)" "unprognostic (5.80e-2)" "unprognostic (8.38e-2)" "unprognostic (9.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-2)" "unprognostic (3.33e-2)" "unprognostic (1.10e-2)" "unprognostic (4.51e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" 0.1 0.0 2.2 1.1 2.1 0.0 25.3 0.4 3.6 11.4 2.8 7.8 25.5 4.2 1.0 0.2 8.0 24.7 0.2 2.0 0.9 162.3 27.7 1.6 0.5 0.6 1.1 0.7 85.4 0.8 0.6 1.1 1.0 7.0 4.2 0.1 3.6 4.8 0.0 1.4 16.1 0.4 0.4 0.2 11.0 2.4 1.3 1.3 31.8 0.0 0.1 0.2 0.3 0.8 0.0 4.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 9.6 0.2 0.0 5.2 0.0 0.6 0.0 0.2 0.1 0.2 0.0 0.9 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.0 0.4 0.1 17.2 0.6 0.0 0.0 0.1 44.8 0.2 6.6 0.1 0.0 0.9 0.0 0.2 4.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 0.4 3.6 2.0 0.9 0.6 1.1 1.0 0.4 1.3 0.8 0.1 0.0 4.4 0.0 1.3 0.0 0.9 0.6 0.0 0.0 20.3 10.8 0.4 105.8 0.0 90.1 0.0 0.1 0.0 7.9 80.3 43.3 7.0 8.3 1.5 0.3 64.1 0.0 0.7 11.8 9.3 0.4 14.8 15.6 0.0 0.0 0.0 10.2 0.3 0.0 0.3 22.0 0.0 0.3 0.0 14.7 0.6 0.8 0.0 0.0 1.0 0.0 0.0 0.0 0.1 5.7 21.3 0.0 0.0 2.2 60.3 79.1 0.0 0.0 0.0 0.0 0.3 3.2 7.9 0.0 0.0 0.5 0.9 0.3 28.9 0.5 KIF13B "GAKIN, KIAA0639" ENSG00000197892 "Kinesin family member 13B" Q9NQT8 8 29067278-29263124 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 64.5;parathyroid gland: 161.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 140.2;Oligodendrocytes: 371.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025023, HPA049655" Enhanced NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA025023: AB_1852471, HPA049655: AB_2732555" "unprognostic (1.37e-1)" "unprognostic (4.31e-1)" "prognostic favorable (8.92e-4)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "prognostic favorable (6.26e-4)" "unprognostic (1.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (9.69e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (9.76e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" 7.4 11.7 25.9 6.8 47.6 5.1 9.2 34.9 30.6 8.7 16.6 18.3 16.1 6.7 9.4 8.4 7.1 8.4 5.3 20.0 29.4 18.5 10.2 8.5 4.3 47.3 43.7 7.2 10.9 161.5 10.0 3.8 42.1 10.9 13.8 7.9 15.6 8.5 4.7 20.0 15.7 5.5 29.3 8.9 19.2 6.6 40.1 5.1 9.0 3.0 4.6 9.5 6.1 64.5 12.4 13.2 4.6 3.8 7.5 4.3 6.7 0.7 2.9 3.9 6.2 8.3 6.9 2.6 6.9 0.8 7.1 8.2 3.7 2.1 5.1 3.9 3.6 6.6 1.8 8.4 7.2 1.8 19.2 5.0 3.9 8.9 3.6 8.3 17.1 4.9 8.6 9.5 12.9 3.8 9.7 3.1 2.3 17.4 2.2 5.5 10.6 4.9 17.0 13.2 1.3 9.1 2.4 8.0 11.7 4.8 5.9 3.7 22.8 2.8 7.6 0.8 5.6 6.9 11.1 4.4 16.4 3.4 13.2 0.1 1.5 1.7 1.5 1.1 0.7 1.4 0.6 0.9 0.5 0.8 0.5 0.6 0.7 0.9 0.6 2.2 0.6 0.5 25.9 47.6 34.9 30.6 20.0 29.4 47.3 43.7 42.1 29.3 40.1 64.5 22.2 44.8 24.8 30.0 16.5 4.5 13.8 17.2 5.2 13.3 23.5 11.2 5.3 20.0 36.8 35.0 60.5 6.4 35.8 95.8 11.7 25.7 8.0 55.3 12.7 14.2 25.2 7.4 26.7 25.0 0.9 10.0 55.0 140.2 41.0 10.6 13.9 18.6 8.9 16.8 35.3 44.1 36.7 25.7 6.3 3.5 8.1 24.4 7.2 41.2 12.1 9.5 12.3 47.3 371.1 39.7 58.0 20.3 42.5 28.1 34.7 17.8 34.9 26.2 6.6 36.4 7.4 6.3 7.7 9.8 6.8 5.1 31.8 5.9 36.0 32.5 KIF17 "KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3" ENSG00000117245 "Kinesin family member 17" Q9P2E2 1 20664014-20718017 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 23.2" "Cell type enhanced" "Detected in many" "Adipocytes: 18.9;Early spermatids: 44.0;Hepatic stellate cells: 15.4;Late spermatids: 88.7;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;hTERT-HME1: 3.7;U-2 OS: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032085 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA032085: AB_10669917" "unprognostic (4.15e-3)" "unprognostic (8.60e-3)" "unprognostic (6.43e-2)" "unprognostic (1.12e-2)" "unprognostic (7.68e-2)" "unprognostic (3.70e-1)" "unprognostic (1.07e-2)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (7.34e-3)" "unprognostic (8.73e-2)" "unprognostic (3.63e-3)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-2)" 0.0 0.2 2.3 0.0 2.2 0.0 0.0 0.0 3.3 0.3 1.8 0.2 0.1 0.4 0.0 0.0 1.8 0.0 0.0 2.3 4.9 0.4 0.1 0.2 0.0 0.6 1.4 0.2 0.0 0.0 0.6 0.0 0.4 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.5 0.3 0.0 0.0 23.2 3.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.8 0.7 0.4 0.0 0.0 0.0 0.1 1.2 1.6 0.6 0.4 0.2 0.4 0.0 0.5 0.9 0.3 0.0 0.6 0.4 0.4 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.1 0.3 0.5 3.7 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.3 0.6 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.2 2.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.2 0.0 3.3 2.3 4.9 0.6 1.4 0.4 0.3 3.1 0.0 18.9 0.0 0.0 0.7 0.2 1.7 0.0 0.1 0.6 0.0 0.2 0.3 2.8 0.0 0.2 1.8 4.2 0.1 2.8 0.1 0.0 0.0 44.0 2.8 0.3 15.2 0.0 0.0 11.0 0.0 0.1 0.9 0.0 0.2 0.0 0.0 15.4 0.5 5.1 0.0 2.8 0.0 0.0 1.6 9.8 88.7 1.2 3.2 1.8 1.9 0.2 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.1 0.1 0.1 0.3 3.5 0.3 19.7 0.5 2.7 3.2 4.3 0.1 1.3 1.6 0.2 5.2 0.1 0.2 KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 244.8;choroid plexus: 142.7;heart muscle: 185.0;skeletal muscle: 561.0;tongue: 389.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 315.4;Distal enterocytes: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024602: AB_1852480, HPA045020: AB_2679187" "unprognostic (3.89e-2)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (8.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (6.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.45e-1)" "unprognostic (4.90e-3)" "prognostic favorable (2.26e-9)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (7.10e-3)" 54.6 18.6 200.1 25.1 230.9 6.3 36.3 184.0 210.0 33.9 142.7 63.3 53.3 44.4 7.9 75.7 31.5 28.0 185.0 164.4 175.0 37.9 46.4 49.6 10.0 219.0 216.9 24.1 51.6 55.1 10.5 18.6 197.0 36.4 33.2 4.3 38.3 36.7 561.0 53.4 51.4 36.3 200.7 26.5 51.2 17.7 200.8 11.3 38.7 389.2 16.7 51.4 37.3 244.8 104.1 97.6 32.2 69.4 74.5 44.5 51.0 80.8 64.3 63.2 38.3 70.7 24.5 16.6 46.7 127.2 41.2 105.3 58.4 107.2 44.6 40.2 68.7 12.0 124.1 57.4 50.7 4.9 34.6 46.0 109.9 85.2 58.0 59.6 87.2 14.5 45.9 28.4 62.6 61.5 14.7 8.0 25.1 68.1 63.4 15.1 54.1 17.2 55.7 71.9 7.8 15.3 114.2 63.0 34.9 30.6 62.0 14.9 185.5 84.8 63.7 62.2 99.3 10.8 9.9 8.9 62.6 20.9 43.0 0.5 0.4 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.4 0.2 0.2 1.2 0.3 0.2 0.2 0.3 0.1 200.1 230.9 184.0 210.0 164.4 175.0 219.0 216.9 197.0 200.7 200.8 244.8 24.8 54.5 50.6 6.5 6.8 16.8 19.0 25.6 12.5 12.5 24.8 14.2 315.4 48.6 28.1 25.8 0.0 14.8 6.5 168.9 19.6 32.2 71.6 13.0 15.1 37.8 14.4 4.4 5.7 43.1 14.0 21.9 51.0 29.3 12.7 21.6 37.1 82.7 16.1 23.5 7.3 77.3 12.2 18.5 11.0 32.1 16.8 11.9 16.0 10.3 16.1 7.7 6.2 4.5 5.0 63.0 83.8 42.5 11.4 44.1 92.9 42.9 18.4 5.8 6.6 35.0 35.1 18.7 23.6 21.3 20.2 23.3 7.9 12.4 65.4 36.6 KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.1;brain: 21.6;retina: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.7;Cone photoreceptor cells: 58.4;Late spermatids: 82.1;Rod photoreceptor cells: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 41.0;JURKAT: 78.8;Karpas-707: 49.6;RPMI-8226: 43.8;U-266/70: 90.2;U-266/84: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Approved "Plasma membrane,Mitotic spindle,Cytosol" Yes No "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Cytosol" "HPA027249: AB_10602241, HPA027274: AB_1852483" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (2.15e-1)" "unprognostic (2.28e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (3.03e-1)" "unprognostic (1.54e-3)" "unprognostic (7.14e-2)" "unprognostic (1.41e-4)" "unprognostic (5.98e-3)" "unprognostic (2.64e-1)" "unprognostic (6.81e-2)" "unprognostic (5.81e-4)" 1.6 0.8 16.1 9.4 16.4 34.1 1.3 0.0 16.5 0.9 0.0 2.4 2.0 0.7 0.4 0.8 1.2 2.1 0.7 21.6 8.3 0.9 1.5 4.8 12.9 5.9 5.7 0.7 0.8 6.0 0.6 0.9 6.5 0.8 1.8 21.4 1.4 0.7 0.3 0.7 6.7 0.8 1.5 12.3 2.5 13.7 9.5 11.8 1.0 0.4 8.0 2.3 0.8 7.9 1.3 1.5 11.8 0.5 0.0 0.0 3.0 0.1 0.0 0.3 0.1 0.7 0.4 39.1 0.5 0.0 3.4 0.3 1.2 0.3 0.4 1.9 0.4 9.7 0.2 0.2 1.0 29.4 41.0 1.0 4.1 0.4 0.7 0.0 1.5 78.8 4.6 49.6 0.0 0.2 24.5 11.2 5.2 3.9 0.0 8.4 0.1 43.8 0.2 0.0 7.2 1.0 0.6 0.5 0.6 2.1 0.2 8.9 2.8 0.0 3.3 0.0 0.2 90.2 44.7 19.3 3.9 12.8 0.3 6.0 0.0 0.6 0.8 0.2 0.9 0.4 0.6 0.8 0.1 0.3 0.5 0.6 1.0 1.3 0.3 0.1 0.6 0.4 16.1 16.4 0.0 16.5 21.6 8.3 5.9 5.7 6.5 1.5 9.5 7.9 1.5 0.0 3.8 22.5 11.0 1.0 0.5 0.2 0.0 25.7 0.4 0.8 1.5 0.0 0.1 1.8 58.4 0.0 17.4 1.2 0.0 0.5 20.4 0.1 0.2 1.8 0.0 4.8 15.6 1.6 0.1 0.6 1.1 0.4 6.3 0.5 1.4 0.3 1.7 1.7 11.8 1.4 0.0 4.4 3.1 82.1 0.9 5.3 0.0 8.4 2.7 20.0 13.4 14.6 4.0 2.4 0.3 0.0 12.0 0.4 0.2 0.0 0.1 26.1 6.6 0.6 1.1 1.9 3.7 0.1 1.0 0.0 18.0 0.1 1.1 2.0 KIFC1 "HSET, KNSL2" ENSG00000237649 "Kinesin family member C1" Q9BW19 6 33391823-33409896 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 47.5" "Cell type enhanced" "Detected in many" "Early spermatids: 32.0;Erythroid cells: 62.3;Extravillous trophoblasts: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 1.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055997, HPA062674" Enhanced Approved Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA055997: AB_2683001, HPA062674: AB_2684829" "unprognostic (7.33e-2)" "unprognostic (1.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (7.07e-8)" "unprognostic (6.34e-3)" "unprognostic (9.36e-3)" "unprognostic (8.58e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.83e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.17e-2)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (4.52e-1)" 1.1 1.1 0.2 10.6 0.3 39.7 2.2 0.3 1.2 2.5 0.4 8.0 8.8 1.8 0.2 11.7 0.8 1.5 0.6 0.7 0.3 0.8 1.0 2.3 24.6 0.4 0.7 2.0 0.7 0.3 0.6 5.5 0.5 0.9 8.2 0.4 2.1 0.2 0.2 9.8 8.1 4.1 0.2 5.3 4.7 12.3 0.6 47.5 0.7 0.4 24.9 2.7 3.9 0.5 133.5 47.9 120.6 124.2 5.2 8.1 64.0 82.5 48.4 122.6 104.6 80.6 53.3 120.2 38.3 41.5 102.0 88.1 87.1 60.7 79.7 114.3 60.3 93.9 71.6 73.5 0.5 96.0 75.7 2.5 4.7 73.2 38.8 13.8 64.2 87.5 76.0 112.3 81.0 86.2 125.7 103.2 47.5 67.6 48.4 129.7 110.7 61.4 38.4 42.8 100.1 57.2 54.3 91.9 44.1 51.3 78.7 105.4 32.2 74.6 104.6 56.2 128.9 58.2 132.4 126.1 18.8 94.8 101.0 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.6 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.0 1.6 0.5 0.2 0.3 0.3 1.2 0.7 0.3 0.4 0.7 0.5 0.2 0.6 0.5 0.4 0.0 2.5 1.0 4.1 5.6 1.5 4.6 2.2 0.4 2.8 2.2 0.5 0.0 1.9 0.0 0.0 18.7 3.7 8.8 0.0 0.7 32.0 2.7 1.9 2.4 0.0 62.3 0.3 0.0 39.6 4.2 4.1 6.1 1.3 15.0 1.8 0.3 14.3 0.0 0.3 8.0 2.0 2.4 9.8 12.0 0.3 4.7 3.6 1.0 3.1 0.3 0.0 1.0 0.6 0.3 2.1 0.7 12.0 0.9 2.1 0.7 0.8 0.5 0.0 2.5 7.5 13.9 9.6 14.4 3.7 6.7 5.7 0.6 12.1 3.1 KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 123.3" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 2.4;SK-BR-3: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 3.3 1.4 0.9 0.8 3.1 0.1 2.5 0.8 1.5 1.8 47.1 2.1 2.7 1.2 8.8 1.1 0.8 1.3 1.1 4.2 1.1 128.7 0.4 3.5 1.0 0.5 0.5 0.1 1.2 135.2 0.3 30.4 0.5 8.0 0.9 0.0 0.8 2.5 0.7 0.6 2.6 1.2 0.6 2.4 2.0 0.5 0.8 0.5 1.3 1.5 0.5 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.1 0.8 1.5 4.2 1.1 0.5 0.5 0.5 0.6 0.8 0.5 15.8 0.0 0.5 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.7 12.9 0.0 0.2 0.0 0.4 5.9 0.0 1.8 0.1 2.5 10.2 16.3 0.4 1.2 0.0 0.1 1.6 0.0 0.1 0.0 0.1 1.1 0.2 2.8 0.0 0.5 1.1 0.0 0.9 1.0 0.8 0.3 1.9 0.0 6.5 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.6 1.8 123.3 0.7 0.0 0.0 1.1 2.3 1.4 0.5 0.0 0.1 0.1 1.1 0.1 1.9 0.1 KLB ENSG00000134962 "Klotho beta" Q86Z14 4 39406930-39451533 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 19.6;liver: 17.7;pancreas: 6.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.6;Enteroendocrine cells: 17.4;Hepatocytes: 51.4;Intestinal goblet cells: 12.1;Spermatocytes: 39.5" "Cancer enriched" "Detected in some" 16 "liver cancer: 11.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 24 "ASC diff: 6.7;Hep G2: 25.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021136 Uncertain NA NA 320000 "Cluster 10: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA021136: AB_1852616" "unprognostic (1.03e-2)" "unprognostic (1.61e-2)" "unprognostic (4.67e-2)" "unprognostic (2.69e-1)" "unprognostic (4.30e-2)" "unprognostic (7.02e-3)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (6.99e-3)" "unprognostic (4.51e-3)" "unprognostic (3.02e-3)" "unprognostic (8.90e-3)" "unprognostic (1.73e-1)" "unprognostic (5.03e-2)" "unprognostic (4.53e-2)" "unprognostic (3.87e-2)" "unprognostic (3.09e-2)" 19.6 0.1 0.2 0.2 0.4 0.3 3.5 0.9 0.6 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.2 0.2 0.2 17.7 1.6 0.0 0.3 0.0 0.0 6.0 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.3 2.8 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.3 0.1 0.0 6.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 25.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.2 0.4 0.9 0.6 0.2 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.6 3.2 19.6 0.0 0.7 0.5 1.1 1.4 0.0 1.6 0.7 1.1 1.2 0.0 1.2 0.0 0.0 0.4 0.5 1.6 0.0 1.1 8.5 4.4 1.5 0.4 17.4 0.0 0.5 4.3 1.5 0.5 2.6 2.2 0.0 0.2 0.4 51.4 0.2 1.7 0.6 12.1 2.0 1.0 0.6 3.2 1.5 0.4 1.8 0.0 0.1 0.4 0.0 0.5 0.2 0.9 4.8 0.7 0.0 1.2 2.1 1.1 0.4 2.3 0.0 1.2 0.5 39.5 0.9 2.0 0.9 1.4 0.8 0.5 1.1 1.1 KLF11 "MODY7, TIEG2, Tieg3" ENSG00000172059 "Kruppel like factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Suprabasal keratinocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: AB_2683664" "unprognostic (9.66e-3)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-3)" "unprognostic (2.63e-3)" "unprognostic (6.34e-2)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (3.08e-2)" "unprognostic (2.48e-3)" "unprognostic (8.96e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-2)" "unprognostic (9.24e-2)" 27.7 15.6 4.0 7.6 3.2 27.8 22.3 8.3 3.9 13.5 4.1 17.9 7.5 20.0 9.7 13.2 13.7 18.1 19.1 2.9 3.9 15.7 35.2 22.4 9.3 3.7 3.3 23.9 54.2 18.3 2.5 19.5 3.4 10.1 9.3 3.0 15.9 14.8 12.1 26.9 8.7 16.8 3.2 18.8 12.4 30.0 3.5 4.0 16.5 27.3 5.5 12.6 13.1 5.1 6.9 3.3 7.8 0.7 5.3 9.4 18.8 7.9 7.9 4.4 4.6 7.8 15.8 0.0 13.9 9.6 17.9 1.6 6.8 6.1 2.9 47.6 5.2 3.5 9.7 1.6 5.2 14.6 22.1 14.7 22.3 8.4 2.3 11.4 3.9 1.3 9.7 30.8 4.6 8.2 0.0 2.7 12.5 5.6 6.7 7.8 0.2 13.6 10.8 8.5 10.0 6.2 12.0 24.5 23.4 12.2 5.7 19.6 11.2 19.3 15.9 14.7 2.6 27.9 36.0 18.7 5.0 3.8 10.4 0.0 8.2 2.0 2.6 12.3 0.8 3.2 1.8 1.9 7.3 2.9 0.5 1.1 0.2 6.6 14.8 0.3 3.0 5.4 4.0 3.2 8.3 3.9 2.9 3.9 3.7 3.3 3.4 3.2 3.5 5.1 58.8 6.4 4.6 0.3 12.5 60.5 17.7 5.5 25.6 6.2 14.3 13.2 3.5 10.0 6.1 7.3 6.2 3.2 10.1 2.5 29.4 8.2 135.0 9.1 21.5 33.3 7.1 4.6 1.7 8.5 4.2 17.5 9.7 26.6 8.2 15.5 37.5 38.1 12.5 3.3 1.4 7.0 16.2 32.4 42.4 25.9 14.6 22.0 30.2 1.0 16.6 2.2 3.1 0.5 0.3 8.9 1.5 16.6 5.3 15.0 6.1 8.4 4.3 5.8 32.9 10.4 35.7 13.8 39.0 13.1 86.2 8.2 10.8 11.2 7.8 11.7 KLF14 BTEB5 ENSG00000266265 "Kruppel like factor 14" Q8TD94 7 130730697-130734207 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.1;testis: 1.0" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 1.8;Early spermatids: 4.1;Late spermatids: 4.1" "Cancer enriched" "Detected in single" 6 "melanoma: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.0;RH-30: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA044729 Uncertain NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" "HPA044729: AB_10960356" "unprognostic (4.49e-2)" "unprognostic (2.62e-1)" "unprognostic (2.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.92e-1)" "unprognostic (9.90e-3)" "unprognostic (7.98e-2)" "unprognostic (5.30e-3)" "unprognostic (7.14e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (7.03e-3)" "unprognostic (3.63e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" 0.6 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.4 0.0 1.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.4 0.0 0.0 KLF15 KKLF ENSG00000163884 "Kruppel like factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cardiomyocytes: 29.7;Distal tubular cells: 29.4;Hepatocytes: 66.9;Peritubular cells: 19.9;Proximal tubular cells: 22.1" "Cancer enhanced" "Detected in many" "liver cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 57.4;HHSteC: 34.8;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: AB_10600819" "unprognostic (3.77e-3)" "unprognostic (1.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-3)" "unprognostic (2.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-2)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "prognostic favorable (3.27e-7)" "unprognostic (6.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.91e-2)" "unprognostic (5.58e-3)" 36.5 6.2 42.2 0.8 50.7 0.1 25.4 45.1 69.5 15.8 37.5 18.6 1.2 19.1 4.1 7.1 29.7 3.5 31.4 41.7 40.6 20.3 92.5 18.6 1.8 64.9 45.9 46.3 48.5 4.5 10.4 1.7 47.2 17.6 0.9 3.9 19.7 5.2 67.3 10.3 10.2 2.5 44.9 3.6 30.2 5.6 44.7 1.2 11.1 32.4 0.8 27.0 12.0 48.4 0.8 0.0 2.2 9.2 57.4 1.0 10.0 0.6 1.4 0.7 1.3 1.1 0.0 3.4 0.9 0.0 1.7 0.1 5.3 0.1 0.2 0.2 2.0 0.1 0.8 7.9 34.8 0.0 0.2 5.4 0.5 0.0 1.2 0.0 0.6 4.5 4.3 7.4 0.2 0.7 0.0 1.3 6.6 1.3 0.3 4.7 0.2 20.2 0.1 0.8 0.7 7.7 0.1 0.3 10.2 3.3 0.5 4.6 0.3 0.3 0.4 0.3 0.3 4.7 0.6 0.7 0.2 1.5 1.3 25.1 7.6 10.3 7.0 10.2 8.2 12.3 7.3 7.4 8.2 11.4 9.4 11.3 16.7 12.8 9.3 9.0 10.5 11.7 42.2 50.7 45.1 69.5 41.7 40.6 64.9 45.9 47.2 44.9 44.7 48.4 1.5 6.4 4.6 22.9 0.8 0.0 2.9 0.2 0.6 1.3 7.8 1.8 29.7 15.7 0.7 0.0 0.0 0.1 0.1 0.0 29.4 0.1 0.1 2.5 4.4 2.1 0.0 2.7 0.6 0.0 0.2 8.1 3.1 3.4 0.0 13.7 8.2 66.9 0.1 0.0 2.8 0.1 0.0 2.6 0.0 0.8 12.2 0.4 1.8 2.8 0.0 12.0 0.0 15.1 5.7 0.4 0.0 19.9 0.9 5.2 0.0 22.1 0.8 3.3 0.0 12.0 5.5 0.1 0.1 0.3 0.0 0.3 0.5 0.6 0.1 1.8 KLF4 "EZF, GKLF" ENSG00000136826 "Kruppel like factor 4" O43474 9 107484852-107490482 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 254.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1054.7;Basal squamous epithelial cells: 832.1;Distal enterocytes: 789.2;Intestinal goblet cells: 710.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.0;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.2;hTCEpi: 84.4;hTERT-HME1: 54.5;OE19: 47.2;U-2197: 111.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002926 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA002926: AB_1852541" "unprognostic (2.06e-1)" "unprognostic (1.42e-2)" "unprognostic (1.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-3)" "unprognostic (3.44e-2)" "unprognostic (6.49e-2)" "unprognostic (3.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "prognostic favorable (3.93e-5)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (8.13e-2)" "unprognostic (8.32e-2)" 73.5 23.9 5.1 21.0 4.7 50.5 63.7 4.0 7.8 53.2 4.6 87.3 28.4 16.0 5.6 102.1 43.0 44.3 31.0 3.7 5.1 6.2 12.4 44.8 5.6 5.0 4.7 29.0 7.0 5.7 4.9 32.4 5.0 16.7 96.0 0.8 27.5 7.6 14.2 254.7 40.5 40.6 4.1 24.1 58.0 17.8 6.0 17.0 25.2 23.2 14.5 43.9 58.9 4.0 13.3 3.9 0.6 0.1 16.6 39.2 5.2 4.4 27.6 6.7 8.1 1.0 18.0 0.0 0.6 6.9 23.7 8.7 6.1 3.9 3.0 0.0 2.2 0.0 7.5 0.3 21.6 0.0 0.0 5.0 84.4 14.0 54.5 1.5 0.6 0.2 0.6 0.0 4.1 7.3 0.0 1.4 4.1 47.2 25.2 0.3 1.6 0.2 2.3 3.7 0.4 0.2 4.0 11.8 15.2 12.7 1.3 5.4 3.5 3.6 0.1 111.5 2.1 0.2 0.1 0.0 3.4 2.6 6.8 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 1.0 0.2 0.0 0.1 5.1 4.7 4.0 7.8 3.7 5.1 5.0 4.7 5.0 4.1 6.0 4.0 1054.7 12.8 41.1 0.3 32.2 436.0 284.3 143.0 832.1 0.5 206.7 205.0 70.3 35.8 71.5 1.8 8.4 49.1 15.0 789.2 1.9 24.4 263.1 154.1 216.0 336.6 123.8 4.8 0.0 38.7 75.5 463.2 537.2 297.4 54.7 4.7 216.0 4.6 89.9 0.0 0.2 710.9 83.4 232.9 282.0 163.0 143.8 401.0 206.3 16.9 36.8 2.0 0.0 0.0 0.0 49.3 540.9 60.5 38.3 187.3 198.0 2.1 46.4 2.0 39.5 463.7 130.0 21.6 15.9 639.9 674.0 107.9 26.8 63.5 332.6 236.8 KLHDC8B MGC35097 ENSG00000185909 "Kelch domain containing 8B" Q8IXV7 3 49171598-49176486 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 128.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 60.7;Sertoli cells: 98.6;Theca cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 28.8" "Group enriched" "Detected in many" 10 "granulocytes: 28.8;monocytes: 8.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008463, HPA014467" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol "HPA008463: AB_1852563, HPA014467: AB_1852565" "unprognostic (1.66e-2)" "unprognostic (1.42e-1)" "unprognostic (5.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.66e-1)" "unprognostic (5.03e-3)" "unprognostic (1.71e-3)" "prognostic favorable (1.47e-4)" "unprognostic (6.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (4.30e-2)" "unprognostic (1.02e-3)" "unprognostic (4.78e-2)" "unprognostic (5.60e-2)" "unprognostic (1.86e-2)" "unprognostic (1.61e-2)" 29.1 128.7 13.5 5.6 14.0 6.1 24.9 9.4 14.8 20.2 24.8 56.1 7.2 26.2 10.6 31.1 26.5 16.7 70.5 12.4 21.2 16.3 12.6 17.3 9.9 12.4 14.2 70.1 9.4 10.4 10.1 12.3 16.1 16.9 3.6 2.3 14.1 13.5 29.6 28.1 14.0 14.2 11.6 13.2 16.7 15.5 19.1 4.3 26.6 13.4 6.8 29.4 22.5 10.3 2.5 5.5 22.4 11.4 13.5 8.0 6.9 8.4 4.7 8.2 6.6 3.6 7.4 0.0 4.6 14.0 2.3 0.1 5.6 5.1 2.1 4.6 1.5 15.1 15.2 9.6 25.6 0.0 8.5 13.3 23.9 10.6 0.8 18.4 21.2 5.3 23.7 0.2 6.3 0.7 1.6 16.7 7.4 1.3 13.1 2.3 2.1 0.7 6.1 1.3 0.9 25.2 6.7 0.2 17.0 4.7 6.8 7.3 9.3 6.2 17.1 11.2 2.6 2.1 0.7 0.3 4.5 0.0 3.1 0.0 5.4 28.8 1.0 8.0 0.4 0.0 0.5 0.7 0.5 0.1 1.8 1.0 9.7 0.0 8.3 0.8 0.2 2.4 13.5 14.0 9.4 14.8 12.4 21.2 12.4 14.2 16.1 11.6 19.1 10.3 14.1 9.6 10.9 5.9 0.9 7.6 11.5 16.4 10.8 2.2 10.8 9.0 60.7 11.5 14.3 7.3 2.1 10.9 2.4 1.0 17.6 14.3 7.2 6.8 6.9 20.5 6.7 6.5 3.8 5.9 8.5 22.3 2.6 3.3 1.3 7.7 37.1 7.5 41.7 0.0 4.6 3.0 18.3 12.0 2.2 7.7 15.2 10.5 12.4 6.5 2.5 29.4 0.0 3.5 0.7 8.6 1.7 14.3 0.6 8.3 0.7 13.4 4.0 2.7 98.6 28.3 31.1 9.2 8.6 15.5 9.8 49.8 1.5 55.5 1.7 7.9 KLHL30 FLJ43374 ENSG00000168427 "Kelch like family member 30" Q0D2K2 2 238138668-238152947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 149.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.5;Skeletal myocytes: 9.8;Smooth muscle cells: 3.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;CAPAN-2: 1.6;EFO-21: 1.5;REH: 1.4;RH-30: 4.5;THP-1: 2.3" "Region enriched" "Detected in single" 35 "olfactory bulb: 9.4" "Not detected" "Not detected" HPA062095 Approved "Centriolar satellite" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Centriolar satellite" "HPA062095: AB_2684680" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (2.07e-4)" "unprognostic (6.02e-5)" "unprognostic (1.29e-1)" "unprognostic (1.22e-2)" "unprognostic (1.31e-1)" "unprognostic (4.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "unprognostic (8.17e-4)" "unprognostic (2.75e-2)" "unprognostic (2.30e-1)" "unprognostic (2.06e-1)" 3.8 0.1 0.2 0.1 0.2 0.0 1.4 0.5 0.2 2.2 0.2 1.0 0.2 1.2 0.0 1.0 1.3 0.5 14.3 0.1 0.4 1.0 0.1 0.9 0.0 0.9 0.8 0.4 0.1 0.0 0.1 0.3 0.3 1.0 0.1 0.1 1.0 0.8 149.1 0.8 0.7 0.7 0.1 0.2 0.5 0.1 0.2 0.0 0.6 15.2 0.0 1.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.1 0.1 0.0 0.0 1.4 4.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.2 0.1 0.4 0.9 0.8 0.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 9.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLHL31 "bA345L23.2, BKLHD6, KBTBD1" ENSG00000124743 "Kelch like family member 31" Q9H511 6 53647916-53665756 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 51.3;skeletal muscle: 146.1;tongue: 34.8" "Cell type enriched" "Detected in some" 33 "Cardiomyocytes: 248.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (7.27e-2)" "unprognostic (6.18e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-1)" "unprognostic (7.67e-4)" "unprognostic (2.23e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-1)" "unprognostic (3.98e-2)" "unprognostic (5.50e-2)" "unprognostic (4.24e-1)" "unprognostic (1.09e-4)" "unprognostic (8.73e-2)" "unprognostic (2.88e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" 8.6 0.8 0.2 0.2 0.5 0.0 3.1 0.2 0.3 0.2 0.7 0.2 0.4 0.2 0.8 0.7 0.8 0.2 51.3 0.1 0.3 0.2 0.4 0.2 0.1 0.3 0.2 0.3 0.4 0.0 0.4 0.1 0.3 1.3 0.2 0.4 1.2 0.1 146.1 1.3 0.3 0.0 0.3 0.1 0.3 0.3 0.3 0.1 0.9 34.8 0.2 0.3 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.0 0.3 0.1 0.6 0.4 0.0 0.1 0.0 0.5 0.7 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.2 0.0 0.8 0.0 0.2 0.2 1.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.1 0.3 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.0 0.0 0.7 0.0 0.6 0.8 0.7 0.0 0.5 0.9 0.9 248.9 0.0 0.5 0.0 0.0 1.0 0.1 0.6 0.0 0.1 0.4 2.0 0.3 1.7 0.0 3.2 0.2 0.4 0.2 7.5 0.5 3.1 0.0 0.9 0.0 0.2 0.2 0.0 0.2 0.1 2.0 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.5 0.0 0.2 0.0 0.1 0.6 0.0 0.2 0.2 0.1 0.0 3.7 2.2 0.0 0.2 0.0 0.4 0.8 0.3 0.4 0.3 0.4 KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 186.3;Microglial cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 323.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" 41.4 22.4 53.9 32.3 53.8 9.0 18.7 44.8 56.5 17.0 29.4 44.4 12.7 19.1 13.5 32.0 9.4 23.1 14.4 49.8 50.0 25.0 42.3 20.2 33.7 53.5 50.2 18.4 11.3 12.9 7.5 28.0 53.0 35.9 16.1 11.8 10.2 66.0 10.7 6.1 13.2 46.1 56.7 21.0 13.1 11.0 55.2 14.6 21.5 18.9 38.9 34.8 9.5 52.6 56.7 78.2 40.9 30.2 22.9 58.5 59.1 44.2 323.1 36.6 35.4 64.6 40.4 86.4 52.4 45.5 192.7 3.3 50.7 112.3 46.6 8.8 10.1 36.8 71.4 46.5 195.6 10.9 11.9 74.5 61.9 55.5 137.7 134.1 73.7 13.8 28.2 17.0 87.1 23.8 11.5 19.6 12.6 14.3 75.5 20.9 53.7 2.1 31.3 23.0 2.8 29.7 25.0 8.0 21.8 49.0 19.3 22.9 94.2 96.8 65.4 25.5 53.8 19.3 18.7 79.0 78.6 28.3 22.9 5.4 2.2 0.4 0.7 3.2 1.1 5.1 1.4 0.8 2.5 3.7 1.1 0.5 2.3 1.0 1.4 0.9 0.2 0.8 53.9 53.8 44.8 56.5 49.8 50.0 53.5 50.2 53.0 56.7 55.2 52.6 74.9 16.0 1.1 45.7 38.0 3.7 9.4 22.9 7.4 18.8 16.5 11.2 4.5 17.2 33.7 11.0 4.2 1.0 6.3 0.3 17.6 39.3 2.8 4.0 11.1 43.6 1.2 10.9 46.1 21.0 57.9 12.6 3.1 5.3 2.5 9.5 22.9 35.6 13.3 70.7 186.3 0.4 12.2 25.4 25.8 6.6 8.1 28.6 17.8 190.2 27.5 12.1 7.2 69.9 79.0 24.3 0.1 13.9 43.0 31.5 2.0 21.8 32.7 3.4 0.0 14.2 17.3 9.8 5.6 3.3 3.4 5.7 10.7 32.4 0.7 14.1 KLLN killin ENSG00000227268 "Killin, p53 regulated DNA replication inhibitor" B2CW77 10 87859158-87863533 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 4.5" "Cell type enhanced" "Detected in many" "granulocytes: 5.7;Sertoli cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "JURKAT: 5.0;Karpas-707: 5.1" HPA074502 Supported Nucleoplasm,Nucleoli No No "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Nucleoli "HPA074502: AB_2686695" "unprognostic (4.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (3.71e-1)" "unprognostic (6.53e-2)" "unprognostic (1.37e-1)" "unprognostic (3.59e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.57e-2)" "unprognostic (4.79e-4)" "unprognostic (1.38e-2)" "unprognostic (1.00e-1)" "unprognostic (9.02e-4)" "unprognostic (1.60e-1)" 1.0 0.7 1.0 0.6 0.7 0.5 0.6 1.5 1.6 0.7 0.6 0.9 0.4 0.5 1.0 0.4 1.4 0.4 0.5 0.7 0.9 0.9 0.9 0.4 0.8 0.5 0.6 0.4 0.2 0.5 0.5 0.6 0.6 0.4 0.8 1.0 0.3 0.5 4.5 0.4 0.4 0.5 0.3 0.8 0.6 1.0 0.6 1.0 0.7 0.5 0.8 0.3 0.3 1.5 0.8 1.0 1.1 0.7 0.5 0.3 0.8 0.7 0.9 0.5 0.7 0.6 2.6 2.0 0.3 0.2 0.5 0.9 0.7 0.8 0.4 0.5 0.3 0.7 1.5 0.6 0.6 1.4 0.5 0.6 0.8 0.7 0.8 0.9 0.3 5.0 0.4 5.1 0.5 1.8 4.1 1.6 0.4 0.6 0.5 2.6 0.1 2.6 0.4 0.8 0.4 1.0 0.9 0.6 0.1 0.7 1.6 1.2 0.3 0.5 0.3 0.9 0.3 2.9 3.3 2.9 0.9 2.9 0.6 1.6 0.3 0.6 0.2 0.5 0.4 0.4 0.3 0.3 0.3 0.5 0.4 0.3 2.5 0.6 0.8 0.5 0.2 0.2 1.0 0.7 1.5 1.6 0.7 0.9 0.5 0.6 0.6 0.3 0.6 1.5 0.6 0.0 0.0 0.3 0.5 0.1 0.3 0.2 0.6 1.7 1.0 1.3 2.7 1.5 1.3 0.0 0.0 0.7 2.0 3.0 0.0 0.2 3.9 0.8 0.9 0.6 0.0 0.8 0.4 0.2 0.4 1.1 3.6 0.4 5.7 0.3 0.7 0.4 0.3 3.3 0.5 1.8 0.0 1.3 0.0 2.0 0.0 0.6 0.0 0.0 0.3 1.6 0.0 0.0 0.1 0.3 2.5 0.0 0.2 0.3 1.8 1.9 2.3 1.0 6.6 1.1 2.9 0.3 1.2 0.6 0.4 0.5 0.7 0.3 1.3 0.2 KLRB1 "CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A" ENSG00000111796 "Killer cell lectin like receptor B1" Q12918 12 9594551-9607916 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 36.4" "Group enriched" "Detected in many" 9 "dendritic cells: 642.3;NK-cells: 1855.8;T-cells: 790.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "MAIT T-cell: 2177.1" "Group enriched" "Detected in all" 140 "NK-cells: 756.7;T-cells: 2177.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039113 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA039113: AB_10674979" "prognostic favorable (3.51e-5)" "unprognostic (1.23e-3)" "unprognostic (7.03e-3)" "prognostic favorable (1.42e-5)" "unprognostic (1.69e-1)" "prognostic favorable (6.99e-5)" "unprognostic (1.54e-3)" "unprognostic (7.15e-3)" "unprognostic (4.12e-1)" "unprognostic (8.23e-3)" "unprognostic (3.57e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.61e-4)" "unprognostic (1.17e-2)" 3.1 1.7 0.7 17.8 0.8 47.4 5.1 0.3 0.8 4.2 0.2 7.7 10.7 1.6 1.4 3.2 1.5 10.7 0.7 0.6 0.7 1.4 11.3 6.7 20.1 0.6 0.6 1.0 0.4 0.2 0.3 1.4 0.6 2.1 8.1 0.1 0.8 1.0 0.7 0.8 20.1 1.6 0.6 28.9 10.1 0.6 0.6 5.7 1.3 0.9 36.4 10.6 1.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.4 0.2 9.5 2.2 1.1 519.7 2.1 2177.1 1.6 307.4 346.1 1.9 1.5 17.1 98.0 10.5 756.7 3.6 3.9 77.9 285.3 0.7 0.8 0.3 0.8 0.6 0.7 0.6 0.6 0.6 0.6 0.6 0.8 6.1 0.0 8.9 0.0 19.0 9.7 0.9 0.0 1.2 0.0 5.2 2.5 1.0 4.3 1.3 0.0 0.0 0.4 642.3 1.7 0.0 0.6 0.0 1.9 1.5 6.2 0.0 118.1 0.4 0.0 0.1 7.9 12.2 2.4 0.0 0.0 45.3 10.1 0.9 0.0 0.6 1.0 0.0 36.2 15.8 0.0 0.0 13.2 24.9 0.0 28.1 0.0 1855.8 2.5 0.1 0.0 3.3 0.0 23.0 1.1 0.9 2.0 0.0 0.0 0.0 1.6 4.1 0.0 0.1 1.2 8.8 1.0 790.5 0.0 2.0 1.3 KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.9;brain: 2.1;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 4 "dendritic cells: 19.2;Oligodendrocyte precursor cells: 36.2;T-cells: 15.9" "Cancer enriched" "Detected in single" 9 "glioma: 0.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.1" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.1" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.4;GAMG: 2.8;HEL: 1.3;HeLa: 7.0;HSkMC: 1.2;SuSa: 1.3;U-698: 1.9" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA039910: , HPA062570: AB_2684795" "unprognostic (8.92e-4)" "unprognostic (4.47e-2)" "unprognostic (2.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.07e-3)" "unprognostic (2.48e-1)" "unprognostic (3.22e-1)" "unprognostic (9.12e-2)" "unprognostic (3.52e-3)" "unprognostic (3.09e-1)" "unprognostic (1.08e-1)" "unprognostic (3.15e-1)" 0.2 0.1 1.3 0.3 1.4 1.9 0.1 0.7 2.1 0.1 0.2 0.5 0.8 0.5 0.1 0.2 0.2 0.6 0.0 1.3 1.7 0.1 0.5 0.6 1.7 1.7 1.1 0.1 0.1 0.0 0.0 0.1 1.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.3 4.0 0.6 0.2 1.3 0.4 0.1 0.0 0.8 0.1 0.1 2.1 0.0 0.0 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.6 0.0 0.0 0.0 1.3 7.0 0.1 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 7.0 0.0 0.0 0.1 8.7 0.6 63.1 0.0 0.0 0.0 3.6 1.3 1.4 0.7 2.1 1.3 1.7 1.7 1.1 1.2 1.3 1.3 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 0.1 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 1.9 0.0 0.0 1.0 36.2 2.3 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.1 KLRC4 NKG2-F ENSG00000183542 "Killer cell lectin like receptor C4" O43908 12 10407382-10409757 "Predicted membrane proteins, Transporters" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.4" "Cell type enhanced" "Detected in some" "dendritic cells: 22.2;NK-cells: 8.2;Plasma cells: 4.7;T-cells: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "gdT-cell: 8.2;memory CD8 T-cell: 5.9;naive CD8 T-cell: 6.7;NK-cell: 4.7" "Group enriched" "Detected in many" 59 "NK-cells: 4.7;T-cells: 8.2" "Cell line enhanced" "Detected in some" "HeLa: 5.5;SuSa: 1.8;U-698: 1.7" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.60e-1)" "unprognostic (7.00e-2)" "unprognostic (1.55e-4)" "unprognostic (1.89e-2)" "unprognostic (1.52e-1)" "unprognostic (3.32e-1)" "unprognostic (2.92e-1)" "unprognostic (4.36e-1)" "unprognostic (3.44e-7)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (5.51e-3)" 0.8 0.7 2.0 2.3 2.1 1.7 1.5 0.9 2.0 0.6 0.2 1.2 1.3 0.8 0.6 0.8 0.5 2.2 0.3 1.6 2.0 0.2 1.2 1.8 4.7 2.2 1.6 0.4 0.1 0.0 0.1 0.5 1.8 0.4 1.3 0.1 1.1 0.1 0.0 0.1 2.6 0.5 1.2 9.4 2.3 0.6 1.9 0.6 0.7 0.0 3.2 0.6 0.5 2.8 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.3 0.0 0.0 5.9 0.0 0.0 0.0 6.7 0.1 4.7 0.0 0.0 0.0 1.8 2.0 2.1 0.9 2.0 1.6 2.0 2.2 1.6 1.8 1.2 1.9 2.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.4 0.0 0.0 0.4 0.0 8.2 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.1 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 KPNA7 IPOA8 ENSG00000185467 "Karyopherin subunit alpha 7" A9QM74 7 99173572-99250075 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "stomach 1: 3.6" "Cell type enhanced" "Detected in some" "Ductal cells: 5.7;Gastric mucus-secreting cells: 5.1;Pancreatic endocrine cells: 11.7;Respiratory ciliated cells: 4.4;Urothelial cells: 11.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 3.8;CAPAN-2: 2.8;OE19: 2.8;SK-BR-3: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA031395 Uncertain NA NA "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA031395: AB_10601584" "unprognostic (7.38e-2)" "unprognostic (7.99e-2)" "unprognostic (2.23e-1)" "unprognostic (8.44e-2)" "unprognostic (8.37e-2)" "unprognostic (9.35e-2)" "unprognostic (9.77e-2)" "unprognostic (2.25e-2)" "unprognostic (2.30e-1)" "unprognostic (3.23e-1)" "unprognostic (7.94e-3)" "unprognostic (5.89e-2)" "unprognostic (2.28e-13)" "unprognostic (2.21e-2)" "unprognostic (1.23e-1)" "unprognostic (3.54e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.5 0.7 0.0 0.5 1.8 0.4 0.0 0.0 0.2 0.1 0.5 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 5.7 0.0 1.3 0.1 0.0 0.0 0.0 0.8 3.1 0.1 0.4 5.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 11.7 2.2 0.0 0.1 1.9 0.1 0.0 4.4 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.1 11.4 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT79 "K6L, KRT6L" ENSG00000185640 "Keratin 79" Q5XKE5 12 52821408-52834311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 68.3" "Cell type enhanced" "Detected in some" "granulocytes: 4.5;Late spermatids: 1.1;Melanocytes: 3.6" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;cervical cancer: 2.6;head and neck cancer: 2.7;melanoma: 1.6;urothelial cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HMC-1: 425.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059347 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA 1900000000 "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Nuclear membrane, Cytosol" "HPA059347: AB_2683986" "unprognostic (5.19e-3)" "unprognostic (1.56e-3)" "unprognostic (5.24e-2)" "unprognostic (2.38e-2)" "unprognostic (6.85e-2)" "unprognostic (6.36e-2)" "unprognostic (3.17e-1)" "unprognostic (7.92e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (3.99e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 425.5 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 KRT9 "CK-9, EPPK, K9" ENSG00000171403 "Keratin 9" P35527 17 41565836-41572059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 12.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.4;Breast myoepithelial cells: 2.9;Extravillous trophoblasts: 2.2" "Cancer enriched" "Detected in some" 6 "melanoma: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.0;HaCaT: 16.8;U-2197: 3.0;U-937: 5.3" "Region enhanced" "Detected in many" "basal ganglia: 25.1" "HPA007261, CAB037322" Supported NA NA 24000000000 "Cluster 63: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB037322: , HPA007261: AB_1079182" "unprognostic (2.13e-2)" "unprognostic (5.08e-2)" "unprognostic (4.97e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (5.92e-7)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-2)" 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.5 0.1 0.1 0.1 0.0 0.0 0.2 0.0 12.1 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.9 0.0 0.0 0.0 0.1 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.2 KY FLJ33207 ENSG00000174611 "Kyphoscoliosis peptidase" Q8NBH2 3 134599923-134651636 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 16.3;skin 1: 9.6;tongue: 27.7" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Excitatory neurons: 10.0;Inhibitory neurons: 11.6;Late spermatids: 6.4;Oligodendrocyte precursor cells: 24.6" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 5.7" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.7" "Cell line enhanced" "Detected in some" "Karpas-707: 2.0;NB-4: 1.1;U-2197: 2.7;U-87 MG: 8.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.2" "HPA036492, HPA036668" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA036492: AB_10672222, HPA036668: AB_2675239" "unprognostic (1.40e-2)" "unprognostic (2.05e-2)" "unprognostic (4.24e-2)" "unprognostic (2.81e-2)" "unprognostic (2.72e-2)" "unprognostic (1.65e-2)" "unprognostic (2.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-1)" "unprognostic (3.86e-2)" "unprognostic (9.87e-2)" "unprognostic (2.83e-2)" "unprognostic (3.82e-1)" "unprognostic (4.62e-2)" "unprognostic (2.29e-1)" "unprognostic (8.98e-2)" "unprognostic (1.47e-1)" 0.0 2.7 1.7 0.2 1.8 0.3 0.8 1.6 2.9 0.8 0.1 0.9 0.4 1.9 0.8 2.0 1.9 0.4 3.1 1.6 1.7 0.3 0.0 0.1 0.0 1.9 2.3 0.9 0.0 2.2 3.3 0.0 2.1 2.2 0.2 1.7 0.8 1.7 16.3 9.6 0.2 4.2 1.5 0.1 0.7 0.3 2.0 0.9 3.0 27.7 0.0 0.6 0.6 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 8.1 0.7 0.0 5.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.6 2.9 1.6 1.7 1.9 2.3 2.1 1.5 2.0 1.9 0.0 0.0 0.0 15.0 0.0 0.6 0.1 0.0 0.0 0.4 0.1 0.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.0 0.0 0.0 10.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 1.0 0.0 2.5 0.0 24.6 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 LAG3 CD223 ENSG00000089692 "Lymphocyte activating 3" P18627 12 6772512-6778455 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.6;ovary: 18.6" "Cell type enhanced" "Detected in many" "dendritic cells: 36.7;Leydig cells: 39.1;Peritubular cells: 69.2;T-cells: 63.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 12.6;MAIT T-cell: 10.0;memory CD8 T-cell: 11.0" "Lineage enriched" "Detected in single" 49 "T-cells: 12.6" "Cell line enriched" "Detected in single" 151 "HDLM-2: 147.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002301, HPA013967" Enhanced "Intracellular and membrane" NA NA 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002301: AB_564101, HPA013967: AB_1846277" "unprognostic (9.39e-2)" "prognostic favorable (3.89e-4)" "unprognostic (8.88e-2)" "unprognostic (7.00e-3)" "unprognostic (1.08e-1)" "unprognostic (6.74e-3)" "unprognostic (8.85e-2)" "unprognostic (4.63e-3)" "unprognostic (1.94e-2)" "unprognostic (1.97e-3)" "unprognostic (8.71e-2)" "unprognostic (9.93e-2)" "prognostic unfavorable (4.62e-11)" "unprognostic (3.07e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" "unprognostic (8.19e-3)" 1.7 0.4 0.3 7.3 0.2 1.5 0.9 0.4 0.7 3.8 4.3 4.5 3.3 6.1 2.8 1.3 3.8 1.2 1.5 0.3 0.4 1.0 2.6 2.5 16.2 0.6 0.3 18.6 0.2 0.1 0.7 0.4 0.5 2.6 2.0 0.8 1.1 7.0 0.2 0.4 5.9 1.9 0.7 23.6 2.1 3.4 0.4 1.6 0.8 0.3 10.9 1.6 3.4 0.5 0.1 0.6 0.8 0.5 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.3 0.4 0.0 0.2 0.5 0.0 0.0 0.5 0.1 0.0 147.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.3 0.1 0.2 0.4 0.2 0.5 0.5 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.6 0.0 10.0 0.0 2.4 11.0 0.0 0.0 0.7 4.2 0.0 0.0 0.0 0.2 2.0 1.1 0.3 0.2 0.4 0.7 0.3 0.4 0.6 0.3 0.5 0.7 0.4 0.5 7.7 0.0 3.3 0.0 1.4 5.1 1.6 0.7 9.6 5.9 12.6 15.5 1.6 0.0 4.3 0.0 10.4 0.3 36.7 2.6 0.0 0.2 0.4 1.2 4.9 4.5 21.7 1.7 0.2 0.0 0.2 7.1 1.5 1.9 0.0 1.0 4.2 3.5 11.5 0.0 0.1 6.3 0.0 4.2 6.2 1.5 39.1 3.3 1.8 0.0 3.4 1.4 2.1 0.0 0.0 0.2 0.8 69.2 10.2 2.4 0.7 0.3 0.3 6.7 6.6 5.9 4.9 0.5 2.4 4.5 3.0 0.1 63.6 0.2 2.9 0.6 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.2;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 370.0;Basal respiratory cells: 447.6;Pancreatic endocrine cells: 853.8;Urothelial cells: 392.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 353.8;HaCaT: 538.2;HBEC3-KT: 1315.0;hTCEpi: 412.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 20000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" 10.9 16.0 2.6 13.1 2.9 10.7 20.7 0.9 21.3 13.2 0.5 26.2 31.5 18.0 2.6 47.2 16.4 11.9 6.8 2.9 2.1 16.3 9.3 28.4 1.2 1.5 1.5 1.1 4.2 0.1 1.7 5.8 1.6 25.9 16.6 0.2 41.5 24.1 6.8 42.1 43.7 2.3 1.7 1.0 73.2 1.0 1.9 5.8 1.2 0.3 13.2 73.1 32.6 2.8 178.4 25.8 0.0 0.4 18.1 11.7 1.0 5.1 15.4 6.0 9.1 68.9 353.8 0.1 15.1 3.7 8.9 538.2 0.1 1315.0 9.1 13.1 1.4 1.1 86.9 1.1 2.4 1.0 1.3 2.6 412.8 19.1 253.4 11.7 6.4 0.1 2.5 6.7 1.9 0.3 0.2 1.2 0.6 81.0 74.0 0.2 17.1 165.4 70.9 109.0 0.5 0.5 73.9 8.5 15.4 1.0 2.0 9.7 138.3 29.1 61.3 1.0 104.6 1.7 3.4 0.4 42.2 0.8 2.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 2.6 2.9 0.9 21.3 2.9 2.1 1.5 1.5 1.6 1.7 1.9 2.8 0.4 221.2 67.7 1.6 1.2 109.7 370.0 447.6 159.9 0.3 11.5 64.4 8.4 4.3 168.5 47.8 0.0 1.1 0.4 247.5 0.0 180.5 6.0 50.8 10.0 3.5 7.8 0.4 2.5 153.0 1.4 7.5 195.7 135.0 18.4 0.2 0.4 3.9 2.0 3.3 2.3 71.7 18.3 0.3 30.0 10.9 1.8 9.9 8.8 0.0 2.1 0.4 0.0 1.0 1.7 853.8 229.1 0.7 2.1 185.0 111.9 2.3 52.2 0.3 0.0 5.3 10.4 0.3 0.6 51.7 26.0 0.5 4.0 0.0 63.1 392.7 LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.3" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 1531.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 574.7;CAPAN-2: 501.6;HBEC3-KT: 2492.2;hTERT-HME1: 1487.5;RPTEC TERT1: 579.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004257, HPA024638, HPA046539, CAB078165" Enhanced Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" No No 130000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" 3.5 0.1 0.2 16.2 1.9 0.1 20.9 2.6 0.6 15.1 0.2 12.1 2.6 12.3 2.1 7.7 34.9 13.0 3.0 0.2 0.2 13.8 0.7 24.9 8.0 0.0 0.1 1.0 3.3 0.0 4.2 10.9 0.1 5.4 12.9 0.1 12.9 6.1 1.7 17.5 15.0 3.3 0.0 0.9 14.9 2.8 0.1 11.3 18.5 2.3 12.3 39.3 6.3 0.2 574.7 25.4 0.0 0.7 4.9 11.9 40.2 4.3 4.7 2.1 0.7 41.4 501.6 0.0 207.9 1.4 16.4 252.4 0.1 2492.2 2.7 0.7 0.2 0.0 0.5 0.1 1.2 0.0 0.2 6.1 189.7 6.0 1487.5 2.3 32.6 0.0 0.0 0.2 2.5 1.1 0.0 0.1 4.5 206.7 35.2 0.1 1.2 0.0 579.4 147.1 30.5 0.1 14.7 0.4 0.9 14.9 2.0 2.7 3.8 2.2 30.2 15.0 7.8 0.9 0.7 0.7 4.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 2.6 0.6 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 218.0 17.8 0.0 0.2 86.3 227.1 232.7 105.3 0.0 8.2 26.2 2.3 10.0 56.8 23.9 0.0 30.7 0.4 74.4 0.0 183.4 19.6 68.9 3.6 7.8 9.0 0.0 0.4 94.0 11.7 17.2 59.7 97.4 0.0 0.0 0.0 0.0 2.5 0.0 0.3 34.1 14.2 0.0 4.9 11.8 3.4 3.1 8.8 1.0 2.6 0.0 0.0 0.0 0.3 1531.1 91.2 0.4 0.3 302.0 16.7 0.2 69.3 0.0 0.0 3.4 9.6 3.6 1.0 60.3 29.7 83.3 5.3 0.1 15.3 169.9 LAMP1 CD107a ENSG00000185896 "Lysosomal associated membrane protein 1" P11279 13 113297239-113323672 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 709.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004260, HPA014750" Supported NA NA 370000000 "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB004260: AB_626851, HPA014750: AB_1846219" "unprognostic (3.98e-1)" "unprognostic (1.18e-1)" "unprognostic (7.55e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.04e-3)" "unprognostic (9.26e-2)" "unprognostic (1.07e-1)" "unprognostic (5.80e-2)" "unprognostic (1.44e-2)" "unprognostic (2.91e-3)" "unprognostic (2.04e-1)" "prognostic favorable (4.15e-5)" "unprognostic (2.06e-2)" "unprognostic (2.22e-1)" "unprognostic (2.59e-1)" "unprognostic (1.54e-1)" 139.2 95.3 83.6 84.1 118.7 72.1 124.6 114.3 89.9 119.3 54.5 108.0 109.8 136.0 103.4 125.1 98.7 91.3 101.3 82.9 96.9 149.1 183.8 148.7 77.2 120.6 106.5 101.7 174.3 109.9 95.0 107.9 119.7 98.0 65.9 35.7 145.0 94.8 71.3 182.3 112.7 92.5 104.7 102.3 108.5 84.8 112.6 63.4 126.7 46.6 55.6 118.6 110.9 138.0 271.7 92.3 93.9 258.1 514.7 192.5 176.7 311.9 325.1 189.8 252.1 181.8 491.1 63.7 139.1 318.6 324.9 338.7 92.9 198.1 128.7 133.8 153.1 105.5 167.6 172.5 265.9 324.5 236.2 236.4 264.6 176.3 114.4 308.4 232.2 61.0 89.3 90.9 236.8 108.9 66.0 158.2 71.5 258.4 99.9 96.1 81.4 96.5 172.3 200.9 85.7 90.1 183.3 268.5 187.6 89.8 259.6 228.0 355.1 193.5 208.2 258.8 141.4 169.4 178.8 66.6 323.4 318.8 229.7 3.8 4.9 9.5 4.0 4.0 3.4 2.2 3.1 4.4 2.5 2.1 3.4 2.8 6.8 3.9 4.4 5.4 3.6 2.1 83.6 118.7 114.3 89.9 82.9 96.9 120.6 106.5 119.7 104.7 112.6 138.0 152.4 86.6 67.2 31.3 64.5 140.8 144.5 68.3 70.0 42.4 131.1 92.5 56.9 123.0 51.4 183.9 77.2 195.6 103.6 248.7 41.1 99.0 272.1 72.7 73.4 113.9 119.2 50.9 22.3 62.3 198.5 173.6 60.6 101.3 71.0 71.3 162.1 303.3 282.9 30.3 22.4 111.1 32.6 208.9 56.8 709.0 163.8 167.6 99.6 34.7 77.6 50.1 104.0 29.7 83.2 82.7 199.2 170.4 51.8 101.4 288.1 178.1 45.1 84.5 118.3 85.0 107.1 163.1 124.7 96.1 197.5 312.4 94.8 72.4 128.6 124.0 LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1393.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" 360.5 451.0 116.8 177.1 114.9 199.5 338.5 120.7 146.8 469.8 150.8 256.2 219.6 507.6 339.7 315.4 370.1 383.7 322.5 112.7 130.2 460.9 409.2 308.0 160.1 123.3 122.2 460.3 290.8 289.2 155.6 397.6 128.1 306.3 233.9 59.1 306.0 611.8 204.4 247.2 227.7 412.2 130.1 190.9 240.5 389.3 125.5 122.8 365.8 234.8 178.5 342.1 248.7 128.0 417.7 228.8 136.4 283.2 1393.4 1031.8 509.1 514.3 651.8 349.3 393.6 180.5 398.4 73.2 116.2 637.9 356.9 400.7 115.0 250.6 317.8 181.2 183.2 112.4 244.3 520.1 534.8 86.7 294.9 691.7 501.2 338.7 386.4 481.9 367.6 62.2 86.6 135.8 527.5 243.3 53.8 114.0 299.2 353.1 207.1 89.3 397.5 139.7 858.6 347.7 214.8 207.3 480.4 390.5 335.9 492.9 169.6 70.1 467.5 575.7 203.8 500.3 336.5 221.7 349.2 118.3 455.3 172.8 234.4 737.8 382.3 289.3 94.6 324.9 116.4 197.4 112.9 106.9 269.2 192.3 126.7 113.7 200.1 124.3 393.4 226.9 119.3 427.0 116.8 114.9 120.7 146.8 112.7 130.2 123.3 122.2 128.1 130.1 125.5 128.0 351.7 195.5 203.1 39.2 156.5 659.0 601.1 1210.5 339.2 24.4 330.3 306.1 211.7 380.3 727.7 553.6 12.5 224.4 109.8 174.8 162.4 539.4 1235.7 195.7 407.1 384.0 138.1 65.0 15.0 347.6 1035.3 896.8 111.6 286.0 521.9 445.7 331.3 519.4 311.3 20.2 14.3 203.6 767.0 299.3 716.0 1080.9 835.3 254.4 588.7 39.4 278.0 315.3 48.4 34.7 18.7 289.4 246.2 600.7 156.8 331.2 171.5 940.9 506.7 24.7 532.5 389.4 583.0 356.3 173.5 268.2 709.8 302.9 146.4 579.1 224.8 500.9 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.5;Alveolar cells type 2: 8.2;Ductal cells: 7.1;Endometrial stromal cells: 10.5;Exocrine glandular cells: 7.9;Glandular and luminal cells: 8.6;Hofbauer cells: 6.0;Pancreatic endocrine cells: 6.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.3;basal ganglia: 23.4;cerebral cortex: 33.2;hippocampal formation: 45.4;white matter: 16.4" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.79e-1)" "unprognostic (1.74e-3)" "unprognostic (1.63e-1)" "unprognostic (1.48e-2)" "unprognostic (4.90e-2)" "unprognostic (1.39e-2)" "unprognostic (5.21e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-3)" 11.9 10.1 18.3 5.9 23.4 0.4 9.1 3.4 33.2 15.3 19.7 27.8 9.2 22.4 8.1 6.7 13.5 9.0 58.4 45.4 2.2 8.4 8.1 6.5 5.1 1.0 2.9 20.8 8.3 6.0 7.4 4.1 4.7 15.2 8.7 13.2 5.9 24.8 49.5 8.5 11.4 15.7 0.0 5.8 16.7 7.6 6.3 2.0 5.3 27.5 5.0 21.6 11.5 16.4 4.1 12.3 19.5 8.4 3.2 0.6 7.4 14.1 7.1 2.7 0.0 2.6 0.4 19.5 2.4 14.0 4.6 1.6 11.6 0.0 0.1 0.3 9.8 0.0 0.0 13.1 4.1 0.1 2.0 1.8 0.9 0.2 0.0 0.0 0.1 0.2 0.2 2.7 3.2 16.5 0.1 9.5 7.7 16.3 0.4 10.6 20.2 3.5 2.5 18.1 7.0 2.4 8.4 11.4 13.6 13.7 16.4 0.6 0.1 8.8 13.8 5.2 3.7 21.3 23.4 0.4 16.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 18.3 23.4 3.4 33.2 45.4 2.2 1.0 2.9 4.7 0.0 6.3 16.4 8.5 0.0 8.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 4.2 4.2 0.0 0.0 2.5 1.8 0.0 0.3 0.9 0.0 0.0 7.1 0.0 5.7 10.5 1.9 0.0 0.0 0.0 7.9 0.7 2.9 0.0 8.6 1.3 3.9 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.4 0.0 0.0 2.0 1.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.3 0.8 1.2 0.0 0.0 LAX1 "FLJ20340, LAX" ENSG00000122188 "Lymphocyte transmembrane adaptor 1" Q8IWV1 1 203765177-203776372 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 21.2" "Cell type enhanced" "Detected in some" "dendritic cells: 23.2;granulocytes: 82.2;NK-cells: 30.9;Plasma cells: 65.1;T-cells: 29.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 14 "B-cells: 7.5;NK-cells: 5.2;T-cells: 12.0" "Group enriched" "Detected in some" 4 "Karpas-707: 22.8;U-266/70: 28.2;U-266/84: 71.9;U-698: 24.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002461, HPA003887, CAB025358" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB025358: , HPA002461: AB_1079239, HPA003887: AB_1079240" "unprognostic (2.85e-3)" "unprognostic (3.83e-3)" "unprognostic (3.90e-4)" "unprognostic (3.65e-2)" "unprognostic (5.22e-2)" "unprognostic (1.03e-5)" "unprognostic (2.99e-2)" "unprognostic (4.91e-2)" "unprognostic (4.36e-2)" "unprognostic (3.31e-3)" "unprognostic (4.77e-1)" "unprognostic (4.36e-1)" "unprognostic (4.23e-4)" "unprognostic (3.07e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" 0.5 0.6 0.2 8.8 0.3 1.6 1.7 0.4 0.4 1.4 0.3 3.7 3.1 0.3 0.3 0.9 0.4 2.6 0.3 0.3 0.2 0.2 0.9 2.7 11.8 0.5 0.2 0.2 0.4 0.1 0.0 0.1 0.5 0.7 3.4 0.1 1.2 0.4 0.1 0.2 2.0 0.7 0.2 7.2 4.5 0.3 0.3 11.1 0.2 0.3 21.2 5.1 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.2 8.0 0.2 22.8 0.0 0.0 8.7 0.0 0.1 0.0 0.0 2.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 28.2 71.9 24.9 0.0 1.9 0.0 0.3 0.0 0.5 12.0 0.0 9.1 7.5 7.1 9.4 0.0 2.5 5.5 7.1 0.3 5.2 0.0 0.0 8.1 3.5 0.2 0.3 0.4 0.4 0.3 0.2 0.5 0.2 0.5 0.2 0.3 0.7 0.9 0.0 1.9 0.0 14.6 1.1 0.4 0.0 0.0 0.0 0.3 0.1 2.6 0.0 0.6 0.0 0.0 0.1 23.2 0.1 0.0 0.2 0.0 0.4 0.4 0.5 0.0 0.0 0.1 0.0 0.0 0.6 1.5 0.4 82.2 0.0 2.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 1.2 0.0 0.0 1.9 10.6 0.0 0.4 0.0 30.9 0.5 0.0 0.1 0.0 0.0 65.1 0.4 0.6 0.1 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.2 0.4 0.0 29.2 0.1 0.3 0.5 LBHD2 ENSG00000283071 "LBH domain containing 2" A0A0U1RRK4 14 103084210-103090027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 11.9;testis: 3.0" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.3;Proximal tubular cells: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: Fibroblasts - ECM organization" 1.7 0.0 1.9 0.2 3.6 0.0 0.5 0.8 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 4.4 0.3 0.0 0.0 0.1 3.6 1.6 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.1 3.0 11.9 0.0 0.0 0.0 0.0 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.6 0.8 2.1 3.1 4.4 3.6 1.6 3.9 0.9 11.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1338.5" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 458.3" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 10.7;HSkMC: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001508, CAB025905" Approved "Secreted to blood" NA NA 25000000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" 58.2 0.5 0.0 24.2 0.1 0.5 6.6 0.0 0.2 4.6 0.0 0.5 0.0 2.6 0.0 0.1 0.6 0.2 3.3 0.0 0.0 8.7 1338.5 1.2 2.8 1.1 0.1 0.2 1.7 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.4 0.0 22.8 0.6 0.6 1.5 0.0 0.5 0.6 0.7 0.4 0.1 3.9 2.0 0.3 0.7 0.2 0.3 0.0 0.1 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.6 0.7 0.0 0.0 0.1 0.0 0.0 7.9 0.8 1.0 0.1 0.2 0.5 0.0 10.7 0.3 11.0 0.1 0.8 0.0 0.7 0.0 0.0 9.7 458.3 0.3 0.0 0.3 0.0 0.0 8.5 0.0 0.3 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 15.2 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062236 Enhanced Supported "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" 28.6 9.1 8.8 53.2 9.7 95.7 17.1 9.3 11.9 27.3 9.2 61.4 40.7 47.0 44.4 29.7 31.8 21.7 10.0 8.5 10.1 19.4 47.3 19.2 81.6 12.0 9.8 19.4 16.9 5.6 6.5 27.6 11.2 23.8 46.2 5.3 11.1 36.7 9.8 13.8 39.9 41.4 10.2 41.5 28.2 20.5 9.5 105.5 11.8 12.8 70.7 32.3 23.0 13.1 122.2 42.0 154.9 69.3 64.8 39.7 77.3 31.2 39.2 65.0 69.0 87.2 207.2 248.4 66.6 32.8 38.6 88.8 114.2 32.9 98.5 142.2 107.1 61.4 40.4 81.5 39.9 274.7 105.5 34.3 21.3 58.9 52.0 33.1 82.9 117.4 189.6 164.6 44.4 16.3 254.9 156.6 140.6 121.8 14.2 164.9 141.4 234.0 75.6 52.7 40.6 53.4 52.7 39.6 26.6 68.2 53.3 181.0 50.5 17.6 91.7 49.3 115.9 56.6 83.0 274.5 24.3 120.5 61.2 83.6 44.3 67.3 43.6 31.6 50.9 39.0 43.5 48.8 38.4 39.5 42.4 52.9 211.4 41.3 25.2 21.5 61.9 69.8 8.8 9.7 9.3 11.9 8.5 10.1 12.0 9.8 11.2 10.2 9.5 13.1 98.1 28.9 36.4 13.4 86.4 27.0 33.4 17.3 21.6 4.5 11.9 11.0 8.5 48.6 34.4 31.3 6.2 40.5 98.3 33.4 5.9 23.6 1.2 31.5 31.0 53.1 27.0 248.9 10.5 19.8 23.9 29.0 29.0 53.9 10.1 24.0 48.5 73.6 44.4 11.8 14.3 43.0 12.2 88.5 18.1 3.4 33.8 71.7 26.6 19.7 56.0 11.6 82.4 37.2 34.1 20.6 24.6 32.4 74.0 32.9 19.3 26.0 26.0 10.4 39.5 13.9 46.6 21.0 26.7 68.4 35.5 11.1 81.3 13.2 73.8 36.7 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "dendritic cells: 143.9;NK-cells: 272.9;T-cells: 255.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in some" 6 "JURKAT: 365.7;MOLT-4: 536.9;U-698: 302.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 3.4 2.2 0.4 50.6 0.5 13.7 2.3 0.4 0.5 2.2 0.7 6.9 7.6 1.7 13.0 3.9 2.1 9.4 1.9 0.5 0.4 3.8 3.8 11.4 111.0 0.8 0.5 1.6 0.9 0.5 0.8 1.1 0.6 2.8 6.5 0.0 4.8 1.4 1.3 1.9 23.1 2.3 0.6 39.9 12.1 1.1 0.5 343.0 3.7 1.4 79.6 13.2 2.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 64.1 3.5 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 365.7 0.2 0.0 0.0 0.0 536.9 0.2 5.9 4.6 0.3 20.6 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.3 0.3 0.4 0.6 0.4 0.0 0.0 1.7 0.1 0.1 0.7 0.3 302.7 0.0 0.1 0.0 12.8 5.2 6.0 1109.8 4.9 1034.8 62.0 1123.8 1201.7 5.2 98.9 1260.7 1168.7 33.6 641.5 6.0 7.7 1682.7 1836.9 0.4 0.5 0.4 0.5 0.5 0.4 0.8 0.5 0.6 0.6 0.5 0.6 4.9 0.0 9.3 0.0 23.4 4.6 1.2 0.4 0.0 0.0 3.5 5.2 1.8 4.3 1.6 3.7 0.0 0.3 143.9 0.9 0.0 0.6 0.1 1.0 0.5 3.4 2.4 10.1 0.2 0.5 0.2 3.1 7.7 0.7 5.1 0.0 4.6 1.5 0.3 0.0 0.2 0.3 0.0 7.8 7.3 0.0 0.0 8.1 3.6 0.0 8.7 0.0 272.9 0.5 0.1 4.7 0.0 0.4 15.7 1.0 0.0 1.4 1.8 0.0 0.0 1.5 2.4 4.5 2.0 0.5 3.1 0.4 255.5 2.9 1.3 1.1 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LDHB ENSG00000111716 "Lactate dehydrogenase B" P07195 12 21635342-21757857 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1947.7;kidney: 1726.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2502.3;Cytotrophoblasts: 1693.0;Distal tubular cells: 3306.5;Proximal tubular cells: 3483.9;Syncytiotrophoblasts: 1639.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 6021.8" "CAB004641, HPA019007" Enhanced Supported Cytosol No No 560000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB004641: AB_425525, HPA019007: AB_2670008" "unprognostic (2.93e-1)" "unprognostic (9.20e-3)" "unprognostic (6.10e-2)" "unprognostic (1.11e-1)" "unprognostic (5.39e-3)" "unprognostic (1.36e-3)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (5.34e-2)" "unprognostic (8.40e-2)" "unprognostic (2.91e-1)" "unprognostic (6.41e-2)" "prognostic favorable (2.51e-4)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (2.55e-1)" "unprognostic (9.32e-2)" 549.9 424.8 509.1 259.2 528.2 352.8 321.1 593.7 617.0 238.6 549.8 320.2 84.4 273.1 169.0 166.6 252.9 232.9 1947.7 484.1 581.9 1726.6 70.5 220.4 425.8 564.4 575.4 472.4 370.3 447.3 161.3 298.2 556.2 240.9 277.0 290.0 162.3 287.2 309.4 81.4 171.3 309.7 537.8 182.0 459.1 119.5 582.5 534.5 348.5 950.4 449.4 417.9 171.2 517.8 647.2 1697.3 1457.5 966.0 1021.7 1126.6 1689.4 879.8 873.0 1201.5 1179.4 2712.9 3.6 2268.6 561.5 597.3 1170.1 315.8 2031.4 1631.4 1518.4 586.5 1413.1 2339.5 1619.0 3.0 975.0 2212.8 967.9 1300.5 572.1 1056.8 1423.4 1416.9 1395.2 1610.8 1304.6 332.6 1342.7 3.2 1895.9 2665.6 4216.4 1051.1 727.7 1681.3 2032.0 1838.7 6021.8 2832.7 467.2 1077.8 403.6 618.1 1586.1 3842.2 5.3 1704.6 548.3 803.7 1048.1 578.5 1684.5 291.0 420.9 2953.4 891.8 1037.5 978.2 540.8 201.9 25.1 346.8 124.7 583.1 349.4 1341.5 723.8 367.2 250.9 1722.4 1124.1 31.7 459.0 95.2 427.7 1405.8 1431.2 509.1 528.2 593.7 617.0 484.1 581.9 564.4 575.4 556.2 537.8 582.5 517.8 89.8 141.1 316.4 68.2 242.2 73.0 439.5 1103.1 221.4 151.5 332.4 325.0 2502.3 298.8 433.9 474.5 68.8 1693.0 208.0 69.6 3306.5 18.4 10.5 224.3 325.0 227.3 92.4 361.2 39.4 314.9 870.1 299.4 222.8 309.4 268.6 412.6 155.7 11.2 612.9 141.3 55.6 152.2 956.2 189.8 104.3 34.3 274.6 174.8 179.7 33.7 197.3 277.6 159.6 47.7 40.3 99.7 84.3 415.2 303.1 310.6 0.2 3483.9 363.0 118.1 236.7 195.2 363.7 21.5 124.3 216.3 64.2 1639.5 398.1 1105.3 257.0 344.9 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;liver: 135.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1" "Cancer enhanced" "Detected in all" "liver cancer: 32.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.1" "Group enriched" "Detected in many" 45 "granulocytes: 11.1;monocytes: 4.8" "Cell line enhanced" "Detected in many" "Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol No NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626" "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favorable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 24.9 14.4 17.7 2.1 19.7 0.7 11.7 20.5 22.6 5.4 34.1 27.2 8.8 3.5 1.1 10.8 5.5 3.0 85.6 16.1 18.9 36.1 135.5 4.9 0.8 20.8 20.2 16.4 18.7 17.0 11.8 0.7 22.4 8.1 9.7 1.3 21.3 3.2 68.7 5.8 5.7 1.2 17.0 1.1 23.1 1.7 19.3 0.5 10.6 52.7 0.6 2.6 3.7 17.5 0.7 2.1 0.0 0.2 1.6 1.4 6.1 0.2 0.1 0.2 0.2 2.8 2.6 0.1 2.1 0.9 1.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.8 11.4 2.6 0.0 14.4 2.0 0.3 0.0 0.0 0.6 0.1 0.4 0.7 2.5 0.0 5.3 0.1 0.8 1.4 2.7 1.3 0.0 0.0 7.8 1.4 0.1 0.0 0.0 0.2 5.2 0.3 0.7 29.1 3.3 0.0 0.0 0.2 0.0 0.0 11.5 0.6 0.0 1.9 0.1 0.0 11.1 2.2 0.6 0.0 3.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 17.7 19.7 20.5 22.6 16.1 18.9 20.8 20.2 22.4 17.0 19.3 17.5 1.6 0.0 6.7 7.8 1.0 0.6 1.8 2.2 0.6 0.5 6.5 2.4 37.3 11.5 2.3 11.0 0.0 2.1 0.1 80.2 37.2 2.3 0.4 2.2 0.3 1.7 3.0 2.7 1.0 6.2 1.2 2.3 32.6 3.8 10.2 2.1 4.2 88.6 7.2 1.7 1.4 11.0 0.0 6.0 1.0 0.6 0.0 3.0 5.4 1.9 2.0 12.0 0.0 1.0 3.2 3.0 28.3 0.0 0.8 2.1 2.4 118.1 2.0 1.4 0.0 4.1 1.3 0.0 0.7 3.6 0.3 3.1 1.0 1.8 15.7 1.5 LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 307.5;breast: 90.1" "Group enriched" "Detected in some" 44 "Extravillous trophoblasts: 124.2;Syncytiotrophoblasts: 432.2" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB010490 Approved "Secreted to blood" NA NA 17000000 19000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010490: AB_2296951" "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" 307.5 0.8 0.1 5.0 0.1 0.1 90.1 0.5 0.3 0.1 0.1 2.0 0.1 0.0 0.0 0.2 0.1 1.2 1.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 2.4 0.0 0.0 4.6 0.1 0.0 0.4 0.0 1.1 0.0 0.7 3.9 1.2 0.1 0.0 0.2 0.5 0.2 0.1 0.3 0.2 1.2 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.8 0.1 0.6 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 124.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.1 432.2 0.1 0.1 0.0 0.1 LETM1 SLC55A1 ENSG00000168924 "Leucine zipper and EF-hand containing transmembrane protein 1" O95202 4 1811479-1856156 "Human disease related genes, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011029, HPA011100" Supported Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA011029: AB_1852804, HPA011100: AB_1852802" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (3.85e-2)" "unprognostic (5.04e-2)" "unprognostic (5.48e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.37e-3)" "unprognostic (1.87e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.77e-4)" "prognostic favorable (8.90e-4)" "unprognostic (8.06e-3)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (2.42e-1)" 13.6 16.3 14.3 7.9 13.7 7.7 10.8 11.7 14.6 8.2 10.8 20.3 13.9 8.4 3.2 23.8 8.0 4.5 19.6 13.4 13.2 13.3 16.4 8.9 7.0 12.7 13.5 9.2 12.5 11.4 8.8 4.9 11.9 8.4 10.7 4.5 9.6 4.2 18.7 15.9 11.7 5.1 12.2 10.7 13.8 14.5 15.0 25.7 10.7 10.9 7.9 8.4 10.6 11.6 22.9 38.1 11.6 36.1 17.4 12.2 20.7 22.1 10.7 21.8 16.9 35.5 24.7 37.5 15.4 23.3 34.0 22.7 29.8 31.2 13.2 25.1 31.1 38.4 30.9 25.6 22.6 39.3 30.3 19.9 22.0 24.9 21.8 10.1 19.0 22.6 51.5 22.9 15.3 25.1 57.3 44.7 30.5 24.7 43.2 32.4 16.2 21.9 17.0 31.3 29.5 26.0 25.2 31.5 13.3 10.0 29.7 20.3 28.8 24.8 14.8 21.1 37.3 19.8 32.7 29.3 22.0 33.8 20.2 3.9 3.7 2.0 5.8 5.0 5.7 4.2 4.9 4.9 4.1 3.6 3.2 4.6 0.5 5.9 5.1 12.9 4.2 2.1 14.3 13.7 11.7 14.6 13.4 13.2 12.7 13.5 11.9 12.2 15.0 11.6 12.2 16.0 11.5 15.0 19.2 40.0 40.7 13.4 8.0 19.4 19.7 10.5 23.3 11.5 14.0 27.6 33.3 17.5 24.9 116.1 31.3 25.5 32.2 9.1 19.4 16.7 15.6 20.4 14.3 31.3 22.6 17.0 32.1 14.7 10.2 17.9 16.1 33.3 21.5 15.2 12.4 29.5 12.2 18.4 19.8 45.1 20.2 13.0 19.6 4.7 13.9 12.7 28.8 9.5 13.2 42.4 52.7 16.6 17.8 58.8 48.8 46.1 5.6 28.4 13.1 23.8 16.1 54.2 44.4 25.2 51.1 15.2 16.7 21.9 53.2 48.4 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 LGALS12 GRIP1 ENSG00000133317 "Galectin 12" Q96DT0 11 63506052-63516774 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 78.3;breast: 41.3" "Cell type enhanced" "Detected in some" "granulocytes: 17.8;Macrophages: 13.3;monocytes: 2.5;Muller glia cells: 3.9" "Cancer enhanced" "Detected in some" "renal cancer: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 20 "eosinophil: 554.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 554.9" "Group enriched" "Detected in some" 14 "ASC diff: 28.9;HL-60: 53.0;NB-4: 109.4;U-937: 112.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA021124 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA021124: " "unprognostic (3.89e-2)" "unprognostic (4.40e-2)" "unprognostic (5.17e-2)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "unprognostic (4.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-3)" "unprognostic (4.69e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (4.60e-7)" "unprognostic (2.72e-3)" "unprognostic (1.19e-1)" "unprognostic (6.22e-2)" "unprognostic (8.60e-2)" 78.3 0.8 0.1 2.7 0.2 18.4 41.3 0.1 0.2 0.1 0.4 0.9 0.5 0.2 0.0 0.2 1.0 1.7 2.1 0.1 0.2 0.3 0.3 1.0 0.1 0.2 0.2 0.2 0.6 0.0 0.0 0.1 0.2 0.4 0.6 1.9 4.5 0.7 0.5 1.0 2.0 1.0 0.2 1.1 0.9 0.0 0.1 0.3 0.7 1.4 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.0 28.9 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.8 53.0 3.3 3.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 109.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 5.3 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 112.2 0.0 15.5 28.1 554.9 0.2 3.3 0.2 0.0 0.0 0.0 7.5 0.1 0.1 0.1 5.7 0.2 0.5 0.7 0.3 17.3 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 1.1 0.1 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 13.3 0.0 0.0 2.5 3.9 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 LGR5 "FEX, GPR49, GPR67, HG38" ENSG00000139292 "Leucine rich repeat containing G protein-coupled receptor 5" O75473 12 71439798-71586310 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.2;fallopian tube: 16.8;placenta: 19.0;skeletal muscle: 22.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 55.2;Endometrial ciliated cells: 35.7;Glandular and luminal cells: 84.4;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 105.0;Syncytiotrophoblasts: 26.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 37.1;SH-SY5Y: 104.5" "Region enriched" "Detected in many" 8 "olfactory bulb: 34.1" "Low region specificity" "Detected in many" HPA012530 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Nucleoplasm "HPA012530: AB_1849329" "unprognostic (5.19e-2)" "unprognostic (3.79e-1)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-3)" "unprognostic (1.52e-1)" "prognostic favorable (5.09e-4)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (3.71e-1)" "unprognostic (8.10e-2)" "unprognostic (2.01e-5)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (6.25e-3)" 1.4 1.6 2.7 0.4 7.6 0.0 1.5 4.6 4.7 1.5 0.1 3.3 5.1 4.0 1.1 0.1 16.8 0.4 0.2 2.9 5.7 0.8 0.9 0.9 0.1 9.5 5.2 0.7 0.0 0.2 1.0 19.0 9.0 1.2 3.6 0.2 1.9 7.3 22.3 2.9 5.5 0.2 6.0 0.0 2.3 0.1 5.6 0.1 0.3 0.8 1.7 0.1 0.4 19.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.5 0.0 11.9 0.0 1.0 37.1 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 12.2 1.6 2.4 0.0 0.0 0.0 14.6 0.2 104.5 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 7.6 4.6 4.7 2.9 5.7 9.5 5.2 9.0 6.0 5.6 19.2 0.0 0.0 0.0 1.3 0.2 0.9 0.0 1.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 55.2 0.0 1.2 0.0 0.0 0.6 35.7 5.3 0.5 4.9 0.0 6.8 0.0 2.3 1.4 0.0 84.4 0.0 0.0 0.0 1.0 6.4 0.0 12.3 3.0 0.0 0.0 1.6 0.2 0.0 0.4 1.8 0.0 0.0 0.0 0.0 45.2 105.0 0.1 0.3 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 1.1 3.4 0.0 0.0 0.0 1.3 26.4 0.5 0.0 20.3 0.0 LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686774-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2;ovary: 2.1;testis: 2.2" "Cell type enriched" "Detected in some" 22 "Theca cells: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009814 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 52: Non-specific - Transcription" "CAB009814: AB_2135467" "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.22e-2)" 1.3 0.8 0.3 0.0 0.4 0.0 0.7 0.9 0.5 0.0 0.7 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.6 0.2 0.0 0.1 0.0 3.2 0.7 2.1 0.0 0.0 0.5 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 2.2 0.8 0.2 0.6 0.1 0.0 0.3 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.9 0.5 0.2 0.6 3.2 0.7 2.0 1.6 0.8 1.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 5.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.3 1.0 1.2 0.1 0.0 6.5 0.0 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 143.2 0.0 0.0 LHFPL6 "LHFP, MGC22429" ENSG00000183722 "LHFPL tetraspan subfamily member 6" Q9Y693 13 39209116-39603528 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 195.2;Endometrial stromal cells: 78.1;Extravillous trophoblasts: 156.9;Fibroblasts: 113.0;Smooth muscle cells: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "myeloid DC: 6.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.2" "Cell line enhanced" "Detected in many" "ASC diff: 255.1;HSkMC: 186.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058975 Approved Approved Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA058975: AB_2683866" "unprognostic (6.98e-2)" "unprognostic (2.71e-1)" "unprognostic (2.00e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (4.10e-2)" "unprognostic (5.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.76e-1)" "unprognostic (5.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (4.41e-3)" "unprognostic (5.25e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (2.30e-4)" 143.2 55.1 46.3 18.6 49.9 1.1 128.7 59.2 45.2 51.6 57.2 51.7 10.8 78.8 47.5 37.0 88.9 74.5 99.7 45.6 57.3 31.9 14.2 82.6 39.1 54.9 56.8 49.6 17.2 18.2 26.9 134.6 51.4 30.8 16.7 11.9 34.7 36.9 32.1 37.9 29.0 68.9 47.8 30.4 27.9 20.4 64.3 17.0 64.2 89.2 17.6 49.1 48.3 44.3 11.5 4.0 118.3 5.1 255.1 115.1 51.6 61.8 88.3 30.8 23.1 0.5 11.6 17.5 1.3 86.6 40.0 17.3 15.0 36.2 25.3 16.9 17.2 47.3 3.7 0.0 26.7 0.8 0.9 186.4 4.7 27.7 45.7 27.6 29.1 1.1 0.0 0.1 59.9 9.9 0.0 14.5 8.8 0.2 15.8 7.7 51.3 0.1 20.9 15.0 0.7 3.8 5.6 7.2 16.8 67.4 6.7 0.1 54.3 77.9 11.7 24.4 33.9 0.9 0.0 48.9 32.4 0.2 57.2 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.3 46.3 49.9 59.2 45.2 45.6 57.3 54.9 56.8 51.4 47.8 64.3 44.3 195.2 3.2 12.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.4 28.6 0.0 0.0 9.9 0.0 0.0 5.0 1.4 0.0 1.9 0.6 0.0 2.7 78.1 32.0 0.0 0.0 0.0 0.6 156.9 113.0 0.0 2.8 2.5 22.1 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 3.6 2.2 0.0 0.0 0.0 131.6 0.0 0.0 0.0 0.0 6.2 1.2 45.8 0.0 0.0 LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "Hofbauer cells: 22.0;Kupffer cells: 79.9;Macrophages: 39.1;monocytes: 48.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cell line enhanced" "Detected in some" "NB-4: 1.7;REH: 2.0;THP-1: 4.0;U-937: 9.1" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" 5.2 3.2 0.9 2.8 1.0 15.5 1.8 1.0 1.5 0.9 0.9 1.5 0.2 1.0 0.2 0.9 4.0 0.4 1.9 1.0 1.0 1.4 3.4 10.3 0.2 2.0 1.2 0.8 1.4 0.1 0.8 0.1 2.0 1.4 0.2 0.2 1.7 0.1 0.5 0.7 1.7 0.4 1.1 57.4 1.6 0.8 1.6 0.2 0.8 0.2 0.3 2.2 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 5.3 7.6 3.0 0.1 11.6 0.1 0.1 0.1 0.1 3.3 0.3 0.1 0.1 31.6 0.4 11.3 0.7 0.1 6.1 0.9 1.0 1.0 1.5 1.0 1.0 2.0 1.2 2.0 1.1 1.6 1.8 0.2 3.2 3.0 0.0 0.3 0.3 1.6 0.0 0.0 0.9 0.4 0.1 0.5 1.5 1.8 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.8 0.0 0.2 0.2 0.6 0.0 0.1 6.3 0.1 0.4 0.4 22.0 0.0 0.0 0.0 0.0 79.9 5.9 0.6 0.0 39.1 0.0 8.4 48.7 0.0 2.1 0.0 0.1 0.0 0.0 0.0 1.1 1.0 0.0 0.1 1.5 0.6 0.0 2.1 0.3 0.3 0.3 0.0 0.1 0.4 1.4 0.0 0.0 0.6 LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.5;lymphoid tissue: 76.3" "Group enriched" "Detected in some" 5 "Kupffer cells: 64.1;Macrophages: 136.1;monocytes: 53.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.7;neutrophil: 137.2;non-classical monocyte: 311.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.2;monocytes: 311.7" "Cell line enriched" "Detected in single" 31 "RPMI-8226: 4.1" "Secreted to blood" NA NA 670000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (8.52e-2)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (6.56e-2)" "unprognostic (2.90e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (6.61e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (3.61e-2)" "unprognostic (6.51e-3)" "unprognostic (4.68e-2)" "unprognostic (6.21e-2)" 7.9 1.3 0.2 36.9 0.2 43.5 1.9 0.2 0.9 0.7 0.6 1.8 0.0 1.0 0.0 0.9 4.1 1.7 2.5 0.3 0.2 1.8 3.8 22.2 0.5 0.6 0.3 0.6 0.9 0.0 0.9 1.6 0.5 1.4 1.2 0.0 1.2 0.0 0.7 0.3 2.8 6.9 0.3 76.3 2.1 0.3 0.4 0.4 1.0 0.0 0.4 15.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 128.6 0.5 0.0 252.7 0.3 0.0 0.0 0.0 39.2 0.1 0.0 0.0 137.2 0.3 311.7 20.3 0.1 65.0 0.2 0.2 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.3 0.4 0.4 0.1 0.0 8.5 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 3.1 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 1.0 0.0 0.0 11.4 0.0 0.4 0.7 6.5 0.0 0.1 0.0 0.0 64.1 14.3 0.0 0.0 136.1 0.0 0.0 53.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.4 2.2 0.0 0.0 0.8 0.2 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 9.0;lymphoid tissue: 16.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 13.8;Kupffer cells: 31.7;Macrophages: 30.6;monocytes: 19.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 3.4;intermediate monocyte: 3.9;neutrophil: 8.2" "Group enriched" "Detected in many" 26 "granulocytes: 8.2;monocytes: 3.9" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" 3.3 1.1 0.0 1.3 0.0 1.6 1.1 0.0 0.1 0.4 0.0 1.0 0.1 0.5 0.0 0.3 2.2 0.2 1.1 0.0 0.0 0.7 1.3 9.0 0.0 0.0 0.0 0.3 0.5 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.4 0.3 0.8 1.4 0.0 16.9 0.8 0.2 0.1 0.0 0.5 0.0 0.0 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 5.3 0.0 0.0 0.2 0.4 0.0 0.1 3.8 0.0 0.7 0.9 13.8 0.0 0.0 0.0 0.0 31.7 5.2 0.0 0.0 30.6 0.0 1.0 19.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 LILRB2 "CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10" ENSG00000131042 "Leukocyte immunoglobulin like receptor B2" Q8N423 19 54273812-54281184 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 35.0;lung: 15.0;lymphoid tissue: 51.2" "Cell type enhanced" "Detected in some" "Kupffer cells: 150.7;Langerhans cells: 61.8;Macrophages: 147.3;monocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "classical monocyte: 61.6;intermediate monocyte: 132.3;neutrophil: 62.9;non-classical monocyte: 153.4" "Group enriched" "Detected in many" 6 "granulocytes: 62.9;monocytes: 153.4" "Not detected" "Not detected" NA NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.23e-1)" "unprognostic (1.12e-2)" "unprognostic (3.21e-2)" "unprognostic (3.51e-2)" "unprognostic (6.21e-3)" "unprognostic (1.70e-2)" "unprognostic (1.44e-2)" "unprognostic (2.94e-1)" "unprognostic (1.08e-2)" "unprognostic (2.98e-2)" "unprognostic (2.64e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.45e-7)" "unprognostic (1.90e-2)" "unprognostic (4.68e-3)" "unprognostic (3.72e-1)" "unprognostic (9.73e-2)" 6.5 2.6 0.0 12.2 0.0 35.0 2.2 0.0 0.5 1.1 0.6 2.3 3.2 1.2 0.1 1.0 3.7 0.0 2.5 0.1 0.1 2.2 3.9 15.0 0.8 0.9 0.5 0.8 1.3 0.0 1.3 0.5 0.6 1.7 0.8 0.0 1.6 0.4 0.6 0.6 3.0 0.4 0.0 51.2 1.8 0.3 1.0 0.2 1.1 0.1 0.0 2.3 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.0 61.6 16.2 0.1 132.3 0.3 0.0 0.0 0.0 18.8 0.1 0.1 0.0 62.9 0.0 153.4 8.0 0.3 29.7 0.0 0.0 0.0 0.5 0.1 0.1 0.9 0.5 0.6 0.0 1.0 0.2 0.5 3.2 10.9 0.0 5.5 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 1.5 3.1 0.0 0.0 0.1 10.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.8 0.0 0.0 0.3 1.0 1.1 0.0 5.1 0.0 2.2 1.5 27.2 0.0 0.0 0.0 0.0 150.7 61.8 0.1 0.0 147.3 3.6 1.0 75.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.3 2.2 0.0 6.6 0.4 0.2 0.0 0.0 0.0 0.6 0.1 2.9 0.0 0.0 0.1 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 LILRB4 "CD85k, HM18, ILT3, LIR-5, LIR5" ENSG00000186818 "Leukocyte immunoglobulin like receptor B4" Q8NHJ6 19 54643889-54670359 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.7;lymphoid tissue: 18.8" "Cell type enhanced" "Detected in some" "dendritic cells: 76.9;Hofbauer cells: 127.6;Kupffer cells: 118.9;Macrophages: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 37.3" "Group enriched" "Detected in many" 44 "dendritic cells: 37.3;monocytes: 10.8" "Cell line enriched" "Detected in some" 32 "Karpas-707: 407.8" HPA052807 Approved NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052807: AB_2681958" "unprognostic (4.09e-2)" "unprognostic (5.75e-3)" "unprognostic (6.06e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.03e-2)" "unprognostic (3.53e-1)" "unprognostic (4.13e-2)" "unprognostic (1.52e-1)" "unprognostic (5.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.91e-2)" "unprognostic (1.08e-1)" "unprognostic (4.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" 8.6 4.6 2.2 10.9 2.5 2.0 3.6 2.7 4.2 1.1 2.2 4.1 1.6 0.9 0.3 1.0 4.0 1.7 2.3 2.2 2.8 2.2 2.9 13.7 11.4 3.8 3.2 0.7 1.6 0.1 2.2 1.4 3.5 1.9 2.3 0.1 3.6 0.3 0.5 0.5 6.3 0.7 3.2 18.8 1.7 0.3 3.0 0.6 2.4 0.0 2.1 6.1 0.8 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 407.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.4 12.8 0.0 0.2 0.0 0.4 0.0 7.8 0.0 0.0 10.8 0.0 0.2 0.0 0.0 11.7 0.5 0.0 0.0 0.1 0.1 8.9 37.3 0.0 3.8 2.2 2.5 2.7 4.2 2.2 2.8 3.8 3.2 3.5 3.2 3.0 3.3 0.6 0.0 4.1 0.0 13.4 0.4 0.0 0.0 0.0 0.2 0.3 1.7 1.0 1.5 1.3 0.0 0.0 0.3 76.9 0.1 0.0 0.0 0.2 0.0 0.0 4.2 0.0 7.8 0.1 0.0 0.9 0.5 0.0 0.0 1.3 0.0 2.2 0.8 127.6 0.0 0.2 0.0 0.0 118.9 12.6 0.6 0.0 104.0 1.8 14.0 29.3 0.2 1.0 0.0 0.0 0.1 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.2 6.6 0.2 0.1 0.0 0.4 0.1 0.1 0.8 2.2 0.0 0.2 0.1 LILRB5 "CD85c, LIR-8, LIR8" ENSG00000105609 "Leukocyte immunoglobulin like receptor B5" O75023 19 54249421-54257301 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.9;lymphoid tissue: 49.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 61.1;Kupffer cells: 103.4;Macrophages: 40.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA012069 Approved NA NA 58000000 "Cluster 17: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA012069: AB_1852873" "unprognostic (3.55e-3)" "unprognostic (5.38e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-2)" "unprognostic (8.86e-2)" "unprognostic (5.44e-2)" "unprognostic (3.02e-5)" "unprognostic (6.80e-2)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (4.14e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" 17.9 10.3 0.2 1.7 0.5 0.9 7.2 0.3 1.0 1.6 1.3 6.1 4.6 1.1 0.8 1.8 4.4 2.8 5.1 0.2 0.2 1.6 7.1 5.3 1.8 0.5 0.3 1.3 0.8 0.3 0.7 4.8 0.4 0.6 4.8 0.1 2.9 0.6 1.8 2.3 6.8 2.4 0.2 49.1 2.5 1.1 1.0 1.0 1.4 1.3 0.7 4.2 1.2 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.5 0.3 1.0 0.2 0.2 0.5 0.3 0.4 0.2 1.0 1.1 0.5 0.0 1.1 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.5 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 1.7 0.0 0.1 0.2 0.0 2.7 0.0 0.0 0.4 0.7 0.0 0.1 0.0 0.1 8.6 0.9 61.1 0.0 0.0 0.0 0.0 103.4 9.8 1.8 0.0 40.1 1.8 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.5 0.0 0.1 0.3 1.1 0.8 0.4 0.5 0.0 0.0 LIMD2 MGC10986 ENSG00000136490 "LIM domain containing 2" Q9BT23 17 63695888-63701172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.1;lymphoid tissue: 222.2" "Cell type enhanced" "Detected in many" "B-cells: 436.9;dendritic cells: 306.6;Kupffer cells: 216.1;monocytes: 188.2;NK-cells: 510.9;T-cells: 264.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 243.0;NB-4: 171.7;SH-SY5Y: 163.3;THP-1: 127.6;U-698: 260.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062432, HPA075172" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA062432: , HPA075172: " "unprognostic (2.90e-3)" "unprognostic (2.89e-3)" "unprognostic (6.34e-2)" "unprognostic (6.53e-2)" "unprognostic (8.72e-2)" "unprognostic (2.00e-3)" "unprognostic (1.81e-1)" "unprognostic (2.67e-2)" "unprognostic (6.68e-2)" "unprognostic (2.01e-2)" "unprognostic (1.20e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.36e-11)" "unprognostic (1.21e-1)" "unprognostic (2.21e-1)" "unprognostic (2.26e-2)" "unprognostic (6.08e-2)" 12.5 7.9 26.2 106.9 31.3 112.1 8.2 18.8 35.4 12.1 19.1 11.2 13.6 7.8 2.0 6.4 8.9 17.5 9.8 29.9 22.6 17.3 10.4 24.8 222.2 22.9 22.1 7.1 7.1 3.3 10.7 15.5 22.3 16.3 9.4 1.0 12.9 5.5 3.1 6.7 61.0 9.1 21.8 170.8 20.5 14.0 22.8 111.3 9.3 3.4 149.8 20.3 8.2 23.7 0.8 7.7 92.9 22.9 0.8 2.4 2.3 2.6 1.4 9.4 6.4 4.2 1.9 243.0 20.5 11.6 9.4 3.9 20.4 0.9 2.6 84.3 8.7 72.4 1.8 20.6 17.6 95.2 7.6 22.8 1.0 9.6 0.3 11.0 25.5 16.5 6.7 13.8 10.7 1.3 84.7 171.7 50.3 0.0 4.4 34.6 37.4 43.6 13.1 1.0 111.2 163.3 11.8 0.2 22.2 23.9 0.6 127.6 32.2 12.8 28.1 0.7 3.4 2.9 1.0 260.4 1.4 13.3 22.7 2144.2 601.8 1434.7 368.9 716.3 364.8 688.5 512.2 432.9 609.8 855.0 679.3 496.3 1248.9 553.2 783.9 230.5 664.2 991.4 26.2 31.3 18.8 35.4 29.9 22.6 22.9 22.1 22.3 21.8 22.8 23.7 11.0 0.0 4.6 0.7 436.9 7.5 7.7 20.5 2.2 1.9 5.0 7.2 1.0 4.3 8.6 11.0 4.2 1.6 306.6 1.1 5.9 20.5 18.8 2.3 14.2 23.6 22.2 99.2 18.7 8.9 3.6 10.1 5.6 4.2 53.3 15.7 30.4 2.0 137.6 3.3 2.2 2.1 26.4 216.1 93.9 57.5 3.4 148.0 37.4 12.2 188.2 8.4 510.9 3.5 2.9 19.8 4.7 4.9 154.3 17.7 0.4 3.7 2.4 1.1 6.6 2.9 30.5 7.8 7.5 1.1 6.0 1.5 264.3 4.7 2.5 4.3 LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 510.1" "Cell type enhanced" "Detected in many" "Adipocytes: 109.4;Cardiomyocytes: 91.7;Endothelial cells: 105.1;Granulosa cells: 134.1;Hepatic stellate cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.5" "Group enriched" "Detected in many" 13 "B-cells: 22.5;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 27.0;fHDF/TERT166: 31.2;HHSteC: 32.7;MOLT-4: 40.2;TIME: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" "HPA058340: AB_2683683" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.82e-3)" "unprognostic (4.51e-2)" "unprognostic (9.25e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.53e-7)" "unprognostic (3.98e-2)" "unprognostic (3.73e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (8.86e-2)" "unprognostic (3.33e-1)" "unprognostic (4.60e-3)" "unprognostic (3.64e-2)" "unprognostic (1.77e-1)" "unprognostic (4.00e-2)" 104.6 21.6 29.4 17.9 27.9 0.4 93.9 24.9 32.3 104.4 25.1 510.1 15.8 261.4 16.9 42.1 139.5 25.7 266.4 25.6 24.1 72.7 46.6 114.3 12.9 28.7 27.2 29.0 14.1 6.4 15.6 27.7 29.3 132.1 15.2 0.6 27.1 98.8 33.4 32.8 95.7 81.9 24.3 121.8 123.1 12.0 32.2 13.1 51.6 26.8 5.4 220.5 85.1 24.0 0.8 1.6 0.5 0.0 4.6 1.0 0.3 19.1 27.0 20.2 18.1 4.7 0.1 0.1 10.3 31.2 1.1 0.1 0.3 0.0 4.2 0.0 0.8 0.0 11.9 3.6 32.7 0.0 0.0 0.2 0.0 7.0 0.2 10.7 12.9 15.3 0.0 0.0 10.0 0.0 40.2 1.0 1.3 0.0 2.4 9.0 1.7 1.0 1.3 0.0 0.1 0.2 3.0 1.7 0.7 6.7 0.7 0.0 83.7 0.1 12.9 15.2 0.1 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.3 0.0 15.2 5.3 1.1 0.2 22.5 10.7 4.4 0.3 0.0 0.2 1.2 8.0 2.5 29.4 27.9 24.9 32.3 25.6 24.1 28.7 27.2 29.3 24.3 32.2 24.0 109.4 22.4 6.1 0.3 10.1 9.4 0.3 0.2 1.2 0.2 1.9 17.1 91.7 4.3 1.3 0.0 0.0 0.6 0.8 0.1 0.0 1.2 1.3 2.9 5.3 105.1 0.0 5.7 0.4 0.2 12.4 22.5 1.1 0.9 2.5 134.1 134.6 16.3 1.0 0.0 0.3 0.0 0.0 6.5 13.0 3.1 19.9 1.7 10.6 30.9 0.0 0.3 0.0 4.0 0.3 0.5 0.0 49.7 1.7 0.3 0.0 0.5 0.8 0.9 26.3 4.2 35.4 0.8 2.1 0.6 6.7 1.0 2.3 1.8 0.0 0.3 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LMNB1 ENSG00000113368 "Lamin B1" P20700 5 126776623-126837020 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.0;lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Early spermatids: 92.5;Erythroid cells: 67.3;Extravillous trophoblasts: 68.2;granulocytes: 93.6;Late spermatids: 72.1;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005269, HPA050524, CAB079757, CAB079954" Supported Supported "Nuclear membrane" NA NA 2100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB005269: AB_648156, CAB079757: AB_2665863, CAB079954: , HPA050524: AB_2681156" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" "unprognostic (4.96e-3)" "unprognostic (3.70e-2)" "unprognostic (1.61e-1)" "unprognostic (8.65e-3)" "prognostic unfavorable (3.08e-6)" "unprognostic (2.06e-2)" "unprognostic (6.62e-3)" "unprognostic (5.28e-2)" "unprognostic (2.13e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.33e-2)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" 4.2 1.6 1.9 26.6 1.8 34.0 2.9 9.8 2.1 3.7 0.5 14.9 11.2 2.8 0.5 14.2 1.8 3.4 1.5 1.6 3.3 3.5 4.9 6.0 34.8 2.9 2.3 2.2 2.4 0.7 2.0 6.7 2.4 1.6 13.0 6.4 3.4 1.6 1.0 8.6 14.2 3.5 2.1 13.3 7.9 2.2 2.3 49.2 1.6 1.4 29.2 6.8 4.8 1.8 132.7 43.4 131.6 126.6 3.3 9.3 170.6 60.6 17.8 66.1 71.3 113.4 107.2 229.4 103.2 21.4 31.5 72.4 90.9 42.1 72.2 162.9 112.1 147.5 49.1 67.2 1.4 176.6 95.6 3.0 0.9 35.2 16.0 12.8 54.9 92.0 87.1 86.3 46.6 109.7 322.8 347.5 99.0 54.1 60.0 152.6 259.4 93.1 36.6 59.6 151.4 80.3 98.4 41.7 36.6 45.2 76.2 202.0 46.9 48.7 132.0 36.6 131.3 56.8 46.4 197.3 25.0 247.1 73.8 1.4 14.4 4.8 2.1 5.6 1.6 4.2 4.3 2.8 15.3 2.9 3.1 2.8 9.3 2.4 1.5 4.6 12.4 6.4 1.9 1.8 9.8 2.1 1.6 3.3 2.9 2.3 2.4 2.1 2.3 1.8 3.4 0.0 4.3 0.3 20.1 5.0 1.9 2.0 8.0 6.4 4.3 5.1 1.6 4.3 3.3 0.0 8.4 39.4 56.0 7.7 1.9 1.8 92.5 3.9 4.8 8.8 6.1 67.3 6.8 0.8 68.2 8.1 11.7 7.6 93.6 23.9 3.6 3.1 21.8 5.0 9.1 19.3 0.0 13.1 17.9 72.1 2.1 27.9 1.8 1.9 59.5 3.8 13.4 5.5 1.1 1.1 8.4 0.4 50.6 1.1 3.8 2.1 1.9 17.5 0.0 2.5 7.3 3.4 8.9 27.3 5.4 4.7 34.2 3.0 35.8 1.4 LMO3 "DAT1, RBTNL2, Rhom-3" ENSG00000048540 "LIM domain only 3" Q8TAP4 12 16548372-16610594 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 93.7;intestine: 85.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Alveolar cells type 2: 210.2;Astrocytes: 293.8;Excitatory neurons: 226.2;Oligodendrocyte precursor cells: 112.6" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 32.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "ASC diff: 189.3;LHCN-M2: 91.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.67e-2)" "unprognostic (2.84e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.10e-7)" "unprognostic (3.62e-2)" "unprognostic (5.44e-2)" "unprognostic (6.56e-3)" "unprognostic (4.91e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.39e-5)" "unprognostic (4.41e-2)" "unprognostic (1.61e-1)" "unprognostic (2.13e-3)" "unprognostic (4.83e-2)" 27.1 8.0 72.8 2.3 89.5 0.0 13.4 35.0 93.7 38.2 25.9 85.6 1.0 18.4 2.7 2.6 7.3 5.2 6.5 85.4 43.5 3.0 0.4 33.8 0.2 42.4 61.9 8.6 39.3 0.7 20.3 1.1 48.2 13.1 9.7 2.7 3.2 28.6 1.6 1.9 14.0 11.3 40.8 0.5 7.1 0.9 67.1 15.3 50.6 1.7 0.0 54.9 18.5 59.2 0.0 0.0 0.2 0.1 189.3 7.4 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.8 0.1 0.0 0.2 0.0 0.0 0.8 0.6 2.5 0.0 0.0 4.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 91.9 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.1 3.6 1.3 14.3 0.0 0.0 0.0 0.2 0.8 0.0 0.7 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.8 89.5 35.0 93.7 85.4 43.5 42.4 61.9 48.2 40.8 67.1 59.2 8.3 173.1 210.2 293.8 0.1 0.3 0.2 5.8 0.0 0.3 2.8 1.4 1.1 0.0 62.8 53.3 18.8 0.2 0.1 0.0 3.9 0.0 5.7 1.8 0.4 0.3 0.0 0.0 226.2 3.6 0.0 23.5 0.0 0.1 5.1 2.5 0.0 0.0 0.2 0.0 46.8 0.0 8.2 0.0 0.5 0.8 0.9 0.7 3.6 18.7 0.0 0.8 0.0 112.6 7.0 0.5 0.0 0.4 0.1 0.2 0.0 0.1 63.7 0.6 0.0 6.3 10.4 1.7 0.8 0.2 0.1 0.3 0.6 0.0 0.0 0.2 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 626.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 582.0;ASC TERT1: 337.0;BJ hTERT+: 426.7;HSkMC: 246.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 30.5 13.3 251.0 18.8 315.0 0.2 25.9 208.8 318.6 57.7 122.2 24.5 13.9 17.0 17.1 15.2 15.8 14.1 24.1 199.5 201.3 9.6 2.6 16.3 17.6 299.6 277.5 12.1 6.6 2.2 5.0 38.8 249.2 21.0 18.3 0.8 16.7 23.6 6.6 20.1 18.3 20.5 224.0 14.8 11.8 6.9 266.2 6.8 16.5 17.5 17.2 27.6 31.7 358.4 11.7 22.2 30.4 0.1 582.0 337.0 0.0 151.6 426.7 104.1 46.8 3.0 1.8 0.0 0.1 157.7 18.6 45.5 0.4 118.5 85.0 0.0 4.1 0.0 1.1 0.0 157.1 0.1 0.2 246.6 6.8 51.4 96.9 62.3 1.8 0.2 0.0 0.2 80.8 0.1 0.0 0.1 5.9 0.0 121.6 0.1 22.4 0.0 23.5 20.6 0.9 7.2 3.1 0.0 0.0 6.2 10.4 0.5 0.1 48.9 1.3 35.3 0.1 1.5 0.0 0.0 7.4 0.0 54.9 1.5 9.1 19.0 0.0 3.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.9 2.1 1.3 0.2 0.0 2.1 251.0 315.0 208.8 318.6 199.5 201.3 299.6 277.5 249.2 224.0 266.2 358.4 1.9 0.0 1.1 6.2 0.2 13.0 15.5 8.5 4.0 0.0 3.4 6.0 1.4 1.5 9.1 0.0 0.0 0.5 0.3 6.6 1.9 1.8 1.4 3.6 40.4 1.9 0.0 0.0 1.0 2.9 0.4 61.4 6.1 8.7 0.0 0.0 2.5 0.0 3.3 0.0 15.6 3.7 4.1 4.1 15.1 2.7 38.8 3.6 14.2 141.5 12.0 1.0 1.0 1.0 626.8 2.0 2.9 70.7 0.7 12.7 4.5 0.2 3.0 0.2 0.0 13.3 6.3 0.3 2.4 15.2 9.2 0.8 1.2 0.2 4.2 6.7 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LRFN1 "KIAA1484, SALM2" ENSG00000128011 "Leucine rich repeat and fibronectin type III domain containing 1" Q9P244 19 39306566-39320863 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 32.5;Cone photoreceptor cells: 8.4;NK-cells: 11.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 16.9;HEK 293: 20.2;K-562: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (4.92e-3)" "unprognostic (2.00e-1)" "unprognostic (6.36e-4)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (1.87e-2)" "unprognostic (6.75e-2)" "unprognostic (4.25e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.45e-3)" "unprognostic (1.08e-1)" "unprognostic (0.00e+0)" "unprognostic (1.89e-3)" "unprognostic (2.10e-2)" "unprognostic (1.31e-3)" "unprognostic (1.78e-1)" 1.3 0.5 5.1 0.6 5.1 0.5 1.2 2.9 8.7 1.3 0.0 1.2 0.4 1.9 0.5 0.7 1.2 0.1 0.4 6.0 4.0 0.5 0.8 1.8 0.4 3.1 1.1 0.8 2.9 0.7 0.9 0.2 1.1 1.0 0.1 1.1 1.0 0.1 0.1 1.1 1.3 0.2 0.0 4.0 1.1 0.7 4.1 1.1 0.9 0.0 0.2 0.5 0.7 2.6 1.2 5.4 0.1 4.7 0.0 0.0 5.6 0.2 0.0 0.3 0.1 16.9 0.6 0.5 2.2 0.0 1.3 0.3 2.1 0.1 0.2 0.5 20.2 0.8 0.8 0.7 0.1 0.3 4.4 0.3 0.2 0.1 0.0 0.4 0.1 6.1 8.9 0.5 0.0 2.8 2.3 2.7 2.3 1.7 5.5 7.5 0.0 1.8 0.0 0.2 1.5 8.0 1.9 3.5 1.4 0.4 1.7 1.8 0.3 1.9 6.6 1.6 0.2 0.8 0.3 2.0 0.1 1.0 0.6 0.4 0.0 0.9 0.2 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.6 0.4 0.2 0.1 0.0 0.0 5.1 5.1 2.9 8.7 6.0 4.0 3.1 1.1 1.1 0.0 4.1 2.6 1.9 0.0 0.0 2.0 0.5 0.8 0.2 0.0 0.0 32.5 1.4 1.5 0.8 1.5 0.0 0.0 8.4 0.7 3.3 0.1 0.0 0.2 0.1 0.0 0.4 1.3 0.0 0.4 5.6 0.7 0.4 0.8 0.0 0.0 0.0 3.2 2.9 1.0 1.0 3.3 5.7 0.0 0.0 3.5 1.4 0.1 0.0 1.9 0.0 1.9 3.7 6.3 11.3 3.5 0.6 0.2 0.0 2.6 0.5 0.7 0.0 0.1 0.0 2.6 0.0 0.0 0.3 1.2 0.8 0.5 0.4 0.8 2.9 1.6 0.0 0.2 LRIG1 "DKFZP586O1624, LIG-1, LIG1" ENSG00000144749 "Leucine rich repeats and immunoglobulin like domains 1" Q96JA1 3 66378797-66501263 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 144.4" "Cell type enriched" "Detected in many" 5 "Astrocytes: 331.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Cell line enhanced" "Detected in many" "Daudi: 79.7;hTEC/SVTERT24-B: 55.2;U-698: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011846 Approved Approved Cytosol NA NA 78000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA011846: AB_2668545" "unprognostic (6.41e-2)" "unprognostic (4.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.58e-2)" "unprognostic (2.12e-2)" "unprognostic (2.28e-1)" "unprognostic (2.32e-1)" "prognostic favorable (3.01e-5)" "unprognostic (5.12e-1)" "unprognostic (7.86e-2)" "unprognostic (2.62e-1)" "unprognostic (2.18e-1)" "unprognostic (2.12e-1)" "unprognostic (8.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (1.50e-4)" 31.0 1.8 33.1 17.0 29.2 4.0 27.2 15.1 21.0 29.9 0.0 38.6 16.8 21.9 3.0 13.5 26.7 20.9 37.0 21.4 26.7 3.6 11.2 17.6 7.9 29.4 39.2 17.1 144.4 5.2 6.5 4.7 17.2 24.8 14.7 5.0 19.2 7.2 37.2 11.7 13.4 30.5 14.3 3.9 36.5 12.5 51.0 3.5 16.2 32.9 9.6 5.9 5.2 17.7 1.4 1.3 27.6 0.5 7.6 4.8 2.8 4.9 26.6 4.6 14.0 23.6 0.3 79.7 13.1 2.2 6.1 0.0 5.5 10.0 10.1 0.0 16.8 0.0 4.1 2.0 1.8 0.7 16.7 6.0 5.4 55.2 9.0 18.8 24.3 0.3 0.3 0.0 1.0 3.6 0.0 0.1 22.8 2.3 0.0 14.1 8.7 3.7 5.1 0.0 3.9 1.0 4.6 4.1 0.2 4.6 25.6 6.7 8.2 13.9 6.3 27.9 12.9 6.2 3.2 59.5 24.3 0.0 5.0 0.0 0.0 0.3 0.1 0.0 0.6 0.1 0.4 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.1 0.1 33.1 29.2 15.1 21.0 21.4 26.7 29.4 39.2 17.2 14.3 51.0 17.7 12.5 38.5 50.2 331.1 4.3 11.3 7.8 8.0 14.2 2.1 51.9 35.8 32.0 11.5 25.0 0.0 8.4 0.2 5.8 9.6 1.9 5.6 1.6 29.1 9.7 9.2 26.5 0.0 10.6 17.1 0.1 17.1 19.9 58.8 1.3 14.9 6.4 20.7 2.0 8.4 15.6 26.2 12.2 1.9 7.7 2.1 11.5 2.4 10.6 57.1 1.7 39.8 0.0 37.7 58.3 6.0 10.2 17.3 8.7 15.6 5.7 1.2 33.7 6.8 0.0 65.5 19.9 1.6 20.0 8.9 11.5 0.1 15.2 2.1 22.8 5.0 LRMDA "C10orf11, CDA017, OCA7" ENSG00000148655 "Leucine rich melanocyte differentiation associated" Q9H2I8 10 75431624-76560168 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation Albinism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 61.5;epididymis: 59.5" "Cell type enhanced" "Detected in many" "Adipocytes: 42.4;Distal tubular cells: 33.2;Endometrial ciliated cells: 27.8;Hofbauer cells: 56.9;Proximal tubular cells: 113.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.6;eosinophil: 22.1;intermediate monocyte: 28.8;myeloid DC: 67.5;non-classical monocyte: 17.1" "Group enriched" "Detected in many" 7 "dendritic cells: 67.5;granulocytes: 22.1;monocytes: 57.6" "Cell line enhanced" "Detected in many" "Hep G2: 46.3;HMC-1: 34.0;NB-4: 65.6;SK-MEL-30: 93.0;THP-1: 48.7;U-937: 43.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047446, HPA050419" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA047446: AB_2680050, HPA050419: AB_2756316" "unprognostic (1.04e-1)" "unprognostic (8.03e-2)" "unprognostic (2.40e-1)" "unprognostic (7.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (8.57e-3)" "unprognostic (5.86e-2)" "unprognostic (6.80e-2)" "unprognostic (8.34e-2)" "unprognostic (1.26e-1)" "unprognostic (7.34e-3)" "unprognostic (7.26e-2)" "unprognostic (6.50e-2)" "unprognostic (4.98e-3)" "unprognostic (3.64e-2)" 16.1 61.5 8.0 5.4 8.6 27.5 10.3 7.7 7.7 12.0 4.7 8.1 5.8 6.4 59.5 7.5 9.7 10.2 13.3 7.8 8.4 20.6 35.8 12.8 5.2 11.5 9.6 13.0 24.9 20.6 10.1 12.7 11.8 10.7 7.2 2.4 9.2 10.0 2.7 3.1 4.5 9.0 10.2 10.5 16.8 3.7 10.9 4.1 18.6 4.8 5.1 11.4 4.5 11.5 0.3 5.7 0.2 0.1 2.9 3.5 0.1 0.7 0.0 0.3 0.5 7.6 13.4 0.0 25.8 0.0 0.1 0.3 0.0 0.0 0.1 0.5 1.6 1.6 2.9 46.3 1.1 9.4 34.0 1.4 1.0 0.6 0.1 5.5 0.8 0.1 0.0 1.4 0.1 1.0 0.1 65.6 0.3 3.9 2.2 0.1 0.2 0.1 0.6 8.3 0.3 0.4 8.1 0.0 93.0 0.2 0.5 48.7 0.9 0.3 3.1 2.4 5.3 0.4 0.2 0.2 22.6 43.6 11.3 6.4 57.6 22.1 0.1 28.8 0.3 0.1 0.0 0.0 67.5 0.1 0.1 0.1 3.2 7.1 17.1 0.5 0.2 18.9 8.0 8.6 7.7 7.7 7.8 8.4 11.5 9.6 11.8 10.2 10.9 11.5 42.4 22.4 19.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 5.7 0.0 0.0 3.7 12.9 0.0 1.1 0.8 0.0 33.2 16.6 0.0 27.8 2.5 13.2 0.0 0.0 0.0 15.8 0.8 4.5 0.0 10.0 7.6 16.1 0.0 0.0 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.1 0.0 0.0 113.4 6.6 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 1.2 0.6 25.7 0.0 0.0 LRRC1 "dJ523E19.1, FLJ10775, FLJ11834, LANO" ENSG00000137269 "Leucine rich repeat containing 1" Q9BTT6 6 53794497-53924125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 115.1;Late spermatids: 117.0;Oligodendrocytes: 138.8;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031603, HPA031604" Enhanced Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031603: AB_10601753, HPA031604: AB_10601224" "unprognostic (2.90e-1)" "unprognostic (8.01e-2)" "unprognostic (9.59e-3)" "unprognostic (2.46e-2)" "unprognostic (7.04e-3)" "unprognostic (1.55e-2)" "unprognostic (2.19e-3)" "unprognostic (6.37e-2)" "unprognostic (7.02e-2)" "unprognostic (7.12e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.97e-1)" "prognostic favorable (2.21e-7)" "unprognostic (1.74e-1)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-3)" 14.0 2.2 8.7 5.1 13.8 2.9 13.3 10.1 11.2 13.2 13.7 25.5 17.3 5.1 7.5 18.2 8.5 7.8 4.2 9.2 10.4 7.7 0.8 7.6 2.7 13.9 10.8 4.8 8.8 22.6 7.9 11.1 14.2 8.7 25.4 7.1 16.7 6.7 1.5 22.5 18.1 5.1 10.9 1.5 14.8 14.5 11.1 13.9 15.3 1.4 10.7 14.5 18.0 24.1 45.2 5.7 6.1 10.9 1.6 0.8 42.8 6.1 12.3 5.2 7.1 49.4 21.7 6.4 4.9 3.9 9.7 21.7 47.9 19.4 6.6 7.9 13.8 3.9 4.5 33.5 15.2 4.9 2.9 1.6 15.8 0.4 11.5 8.1 9.4 23.1 0.9 5.8 2.9 19.7 33.6 0.6 4.8 33.5 4.2 6.8 10.2 3.3 14.1 57.4 15.7 1.5 7.3 31.7 9.9 15.2 20.6 5.0 4.3 3.9 12.6 0.2 5.6 5.8 4.9 4.6 4.4 6.7 4.8 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.3 0.5 0.1 0.1 0.0 0.7 0.0 0.3 0.0 0.0 8.7 13.8 10.1 11.2 9.2 10.4 13.9 10.8 14.2 10.9 11.1 24.1 19.8 41.7 3.9 53.2 2.9 52.6 25.5 16.3 12.0 43.0 16.0 8.1 3.5 11.5 20.6 16.5 4.2 54.5 2.3 115.1 7.9 20.5 88.5 38.8 9.4 18.8 18.0 1.7 11.9 15.6 62.0 5.9 26.0 74.3 5.7 10.5 8.6 0.3 5.1 8.4 21.9 23.6 12.2 0.6 7.1 117.0 9.3 1.3 10.6 26.2 2.5 32.7 6.2 35.2 138.8 29.5 62.5 10.1 4.2 18.5 32.5 12.3 14.1 3.0 6.6 3.5 3.7 27.3 7.3 19.9 52.7 107.4 3.1 1.6 24.5 32.5 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LRRC31 FLJ23259 ENSG00000114248 "Leucine rich repeat containing 31" Q6UY01 3 169839172-169869935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 21.7;salivary gland: 6.5;stomach 1: 10.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 8.9;Enteroendocrine cells: 10.3;Intestinal goblet cells: 23.5;Paneth cells: 6.0;Undifferentiated cells: 5.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.9;HAP1: 1.4;OE19: 8.8;RPTEC TERT1: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA058013 Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA058013: " "unprognostic (5.15e-2)" "unprognostic (5.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (9.90e-2)" "unprognostic (4.40e-2)" "unprognostic (7.90e-3)" "unprognostic (2.49e-2)" "unprognostic (1.64e-2)" "unprognostic (3.20e-4)" "unprognostic (3.14e-1)" "unprognostic (2.61e-1)" "unprognostic (2.27e-1)" "unprognostic (5.96e-3)" 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 1.4 0.0 17.5 8.4 0.1 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 5.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 21.7 0.1 6.5 0.0 0.0 0.0 9.6 0.4 0.0 0.1 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.8 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 1.0 0.3 0.0 10.3 0.0 0.3 0.0 0.0 0.0 3.1 3.0 0.0 0.0 0.0 2.4 0.1 0.0 0.2 23.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 6.0 0.0 0.0 0.1 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.4 LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 78.0;Endothelial cells: 88.3;Extravillous trophoblasts: 164.2;Hepatic stellate cells: 95.3;Sertoli cells: 39.5;Smooth muscle cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in some" 6 "ASC diff: 115.0;ASC TERT1: 70.3;HSkMC: 44.0;HUVEC TERT2: 51.4;U-2197: 108.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" 104.5 34.3 12.6 10.5 12.6 2.4 63.6 11.2 11.8 56.2 8.4 23.2 8.9 36.4 6.2 10.3 31.6 29.0 55.7 9.6 10.6 64.7 11.3 109.0 4.3 12.2 13.8 13.5 12.0 7.5 16.7 53.0 13.0 24.9 6.1 1.3 12.8 11.0 23.6 26.6 21.4 15.2 10.9 28.9 21.3 3.6 15.0 2.0 42.3 6.2 1.5 36.7 28.8 11.5 0.0 0.0 1.3 0.0 115.0 70.3 1.4 0.4 0.8 0.1 0.1 0.0 0.0 0.2 3.1 1.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 11.8 0.6 0.0 2.2 0.0 0.1 44.0 0.0 4.1 0.2 0.9 51.4 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 7.6 0.2 0.0 13.8 7.5 0.8 108.3 0.0 0.1 0.0 1.9 5.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 4.3 12.6 12.6 11.2 11.8 9.6 10.6 12.2 13.8 13.0 10.9 15.0 11.5 78.0 0.0 4.3 0.0 1.7 14.5 0.3 0.0 1.8 0.0 0.6 0.6 10.4 0.0 1.3 0.0 0.0 1.9 0.1 0.2 0.0 0.3 1.3 0.1 1.9 88.3 0.0 5.3 0.0 0.0 164.2 26.4 0.5 0.3 2.5 0.5 95.3 0.6 3.6 0.0 0.1 0.4 0.0 3.1 19.0 1.9 9.0 2.9 17.8 14.0 0.0 0.4 0.0 0.0 0.1 0.0 2.2 9.1 0.2 1.4 0.0 0.4 0.7 0.1 39.5 2.1 47.6 0.4 4.7 0.6 12.5 8.3 1.6 0.4 0.1 1.2 LRRC46 MGC16309 ENSG00000141294 "Leucine rich repeat containing 46" Q96FV0 17 47831634-47837719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "fallopian tube: 78.4;testis: 54.3" "Group enriched" "Detected in some" 6 "Early spermatids: 143.1;Endometrial ciliated cells: 166.7;Late spermatids: 61.5;Respiratory ciliated cells: 225.8;Spermatocytes: 125.7" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 11.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "T-47d: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021882, HPA074893" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA021882: AB_1853320, HPA074893: AB_2732271" "unprognostic (1.06e-1)" "unprognostic (6.01e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.40e-1)" "unprognostic (2.81e-2)" "unprognostic (4.27e-2)" "unprognostic (1.61e-1)" "unprognostic (1.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.21e-3)" "unprognostic (3.63e-2)" "unprognostic (2.98e-3)" "unprognostic (1.10e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (2.14e-1)" 0.2 0.3 1.4 0.1 1.0 0.5 0.3 1.3 0.8 2.6 4.2 0.1 0.1 1.1 0.9 0.2 78.4 0.2 0.3 1.0 1.8 0.7 0.5 4.8 0.3 2.4 6.7 0.3 0.5 0.2 1.7 0.1 3.2 0.5 0.0 2.3 0.3 0.3 0.1 0.1 0.2 0.0 3.1 0.5 0.2 54.3 1.3 0.4 0.9 0.0 0.1 0.2 0.2 2.1 0.7 2.8 0.3 1.4 0.2 0.4 0.8 0.1 0.8 0.7 1.3 1.1 0.7 0.2 1.7 0.3 0.8 0.7 0.3 0.6 1.1 1.1 1.2 0.6 0.9 0.5 0.1 0.0 0.7 0.0 0.5 1.7 0.5 0.2 0.1 0.4 0.6 0.4 1.1 1.2 1.1 0.0 0.1 0.2 0.4 0.9 0.0 0.6 1.4 0.5 1.2 0.9 0.3 0.0 0.5 0.1 3.6 0.1 0.2 1.6 0.5 0.2 0.2 0.6 0.5 0.5 1.1 0.2 0.1 1.3 0.4 0.5 0.0 0.5 0.0 0.1 0.0 0.3 0.7 0.1 0.2 0.0 0.5 0.8 0.4 0.3 0.0 0.1 1.4 1.0 1.3 0.8 1.0 1.8 2.4 6.7 3.2 3.1 1.3 2.1 0.3 0.0 2.3 0.0 0.5 0.0 0.3 9.7 0.0 0.6 0.7 0.9 0.5 1.5 21.9 5.5 2.1 0.1 0.4 0.2 0.0 0.9 143.1 166.7 1.9 0.4 0.0 0.4 0.2 0.0 0.5 1.2 0.0 3.3 0.0 0.3 0.0 0.1 0.5 0.0 0.3 0.6 12.2 0.0 0.3 61.5 2.8 1.0 0.0 1.0 0.8 1.0 0.0 0.0 0.4 0.6 1.1 1.9 0.2 0.3 0.1 1.4 225.8 7.0 0.0 0.4 3.7 125.7 4.2 0.0 0.0 0.1 0.7 0.3 0.0 0.2 LRRC56 "DKFZp761L1518, FLJ00101" ENSG00000161328 "Leucine rich repeat containing 56" Q8IYG6 11 537527-554912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.3;testis: 22.3" "Group enriched" "Detected in many" 6 "Early spermatids: 68.0;Late spermatids: 141.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;Daudi: 1.3;Karpas-707: 2.4;SK-BR-3: 1.6;T-47d: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038728 Approved NA NA "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "HPA038728: AB_10671864" "unprognostic (2.77e-2)" "unprognostic (9.54e-3)" "unprognostic (1.28e-2)" "prognostic favorable (7.39e-4)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (2.29e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.65e-3)" "unprognostic (1.86e-1)" "prognostic favorable (6.32e-4)" "unprognostic (1.17e-1)" "unprognostic (7.89e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.56e-1)" "unprognostic (1.52e-3)" 0.8 0.8 0.5 0.1 1.9 0.2 1.6 0.3 0.5 2.4 0.6 1.7 0.1 0.9 1.3 2.7 6.4 0.0 0.5 0.8 0.3 3.2 1.6 2.9 0.0 0.5 0.3 1.8 2.4 0.0 12.3 0.0 0.1 3.7 0.0 0.1 2.0 0.3 1.2 2.5 2.2 0.0 0.4 2.2 2.1 22.3 0.6 0.1 2.7 0.0 0.2 1.2 2.0 0.3 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.4 1.1 0.4 0.8 0.0 0.2 0.0 0.0 0.5 0.0 2.4 0.0 0.0 0.1 0.7 0.0 0.7 0.7 0.0 0.0 0.5 0.2 0.0 0.3 0.2 0.0 1.6 0.0 0.0 2.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 1.9 0.3 0.5 0.8 0.3 0.5 0.3 0.1 0.4 0.6 0.3 0.5 0.0 3.4 3.3 3.0 1.7 1.5 1.5 0.0 1.1 2.1 0.9 0.6 1.5 2.4 3.7 16.7 0.3 0.6 4.9 0.0 1.1 68.0 11.6 0.6 0.5 12.5 0.4 5.2 0.4 0.2 1.1 1.5 1.3 0.0 0.5 1.1 0.3 0.3 6.7 3.8 2.1 6.1 0.6 0.3 141.2 1.2 0.3 1.8 1.0 0.0 2.7 1.0 1.5 2.8 0.5 1.4 1.2 0.1 1.2 0.2 0.8 14.4 7.0 0.0 0.2 0.6 6.6 2.2 0.6 0.9 0.5 1.4 0.7 0.6 0.8 LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 73.5;Excitatory neurons: 73.6;Inhibitory neurons: 99.2;Microglial cells: 185.5;Oligodendrocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.9;monocytes: 6.6;T-cells: 11.3" "Cell line enhanced" "Detected in many" "THP-1: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Approved "Golgi apparatus" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 28: Placenta - Pregnancy" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA029347: AB_10601544" "unprognostic (2.61e-2)" "unprognostic (3.09e-2)" "unprognostic (3.83e-2)" "unprognostic (1.76e-2)" "unprognostic (3.32e-2)" "unprognostic (1.65e-2)" "unprognostic (5.02e-2)" "unprognostic (3.76e-3)" "unprognostic (4.28e-2)" "unprognostic (4.90e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.78e-2)" "unprognostic (4.42e-2)" "unprognostic (1.94e-2)" "unprognostic (3.38e-2)" 14.3 7.6 3.8 9.0 4.5 8.0 7.7 4.5 5.8 3.2 11.4 3.2 3.2 7.3 1.9 2.9 2.8 6.6 6.2 4.1 4.1 2.5 3.3 7.7 12.2 4.6 5.0 5.3 1.8 2.8 2.3 6.6 5.1 2.3 3.7 1.6 2.0 2.0 2.7 6.0 3.8 15.8 4.8 9.2 2.9 4.0 4.7 5.6 3.5 8.0 7.7 6.2 2.0 6.0 0.3 3.8 3.0 2.7 9.1 10.2 1.4 19.3 21.6 8.7 8.0 0.0 1.3 6.0 5.3 8.5 14.9 13.1 10.1 29.0 20.9 14.8 6.1 5.7 2.9 0.3 7.4 26.6 1.9 4.4 5.8 18.8 10.0 5.8 35.6 9.2 3.9 7.9 7.5 0.7 3.9 26.2 3.3 0.1 7.8 26.5 1.4 2.0 1.8 3.2 2.3 10.7 7.1 0.7 16.2 4.7 0.2 41.3 29.9 15.3 7.3 5.3 14.9 2.9 2.6 3.1 4.7 19.6 2.6 0.4 6.0 0.0 3.8 5.2 3.3 0.7 6.1 5.1 8.9 0.5 4.8 4.5 0.8 2.0 6.6 0.7 11.3 3.2 3.8 4.5 4.5 5.8 4.1 4.1 4.6 5.0 5.1 4.8 4.7 6.0 73.5 3.2 3.6 31.3 7.6 45.4 3.8 5.6 3.4 2.3 1.7 2.9 6.3 2.8 2.7 0.0 0.0 0.1 24.6 0.3 0.0 1.7 36.3 0.2 1.9 47.3 1.2 4.8 73.6 2.4 1.1 8.7 2.6 0.6 0.0 58.5 28.9 0.1 13.6 1.7 99.2 0.3 2.0 29.5 36.9 21.3 0.0 27.8 26.6 185.5 21.3 0.5 13.4 22.1 85.2 12.8 1.9 0.7 20.8 2.1 0.3 0.6 2.9 1.2 0.0 2.2 24.2 3.9 2.0 1.3 44.9 0.3 27.1 3.4 0.3 2.5 LRRFIP1 "FLAP-1, FLIIAP1, GCF-2, HUFI-1, TRIP" ENSG00000124831 "LRR binding FLII interacting protein 1" Q32MZ4 2 237627587-237813682 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 322.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006979 Approved Supported Cytosol NA NA 580000 "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA006979: AB_1079282" "unprognostic (2.07e-1)" "unprognostic (2.99e-2)" "unprognostic (4.09e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (9.68e-3)" "unprognostic (3.08e-2)" "unprognostic (3.99e-3)" "unprognostic (8.90e-2)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (2.69e-2)" "unprognostic (8.07e-2)" "unprognostic (7.64e-2)" 44.2 21.0 11.3 49.2 9.0 86.8 34.0 3.8 11.0 34.1 23.0 63.2 35.9 64.3 15.7 58.2 32.1 39.4 69.7 11.7 10.8 51.7 48.9 61.7 45.4 7.3 6.9 16.0 21.2 55.1 14.8 41.4 7.0 40.9 40.3 6.4 38.0 31.2 111.0 23.7 35.9 58.8 5.9 45.7 49.6 5.4 9.4 43.5 37.8 50.7 52.6 69.4 43.4 7.3 99.1 50.1 17.5 45.9 25.4 55.6 77.7 67.4 62.3 37.8 37.2 19.2 64.6 8.4 27.4 108.8 81.2 80.9 54.0 100.4 80.2 322.6 34.7 78.0 55.1 54.8 58.5 104.2 71.0 23.9 205.8 88.2 216.0 50.6 59.8 54.0 58.4 77.8 79.5 47.8 60.5 79.5 29.6 73.3 45.1 87.9 125.3 80.1 122.0 141.8 46.3 24.0 33.5 76.2 92.2 37.6 42.9 129.2 99.4 42.4 41.1 49.5 77.0 15.8 14.3 53.2 63.4 102.7 51.0 78.5 104.1 248.4 74.8 97.5 55.1 55.9 89.0 77.3 84.1 60.1 46.1 52.2 326.2 46.9 168.9 73.1 76.7 61.4 11.3 9.0 3.8 11.0 11.7 10.8 7.3 6.9 7.0 5.9 9.4 7.3 236.4 487.2 307.3 35.6 249.6 307.0 391.9 166.0 113.3 46.4 128.6 86.2 160.3 127.2 269.9 172.9 37.5 111.2 347.1 319.5 52.8 229.7 7.9 368.3 88.2 213.0 190.5 62.4 175.9 333.0 359.2 109.1 159.0 426.3 241.0 56.9 122.0 149.1 175.8 21.9 237.5 168.3 79.3 271.2 721.3 7.9 29.8 398.9 167.2 57.1 365.0 25.1 213.1 111.1 12.5 389.6 220.6 23.3 146.6 430.5 152.8 49.5 286.1 6.0 78.9 147.3 182.9 10.1 27.4 179.3 243.1 25.3 288.5 158.3 150.0 588.4 LRRIQ3 "LRRC44, MGC22773" ENSG00000162620 "Leucine rich repeats and IQ motif containing 3" A6PVS8 1 74026015-74198187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 20.4" "Group enriched" "Detected in many" 5 "Early spermatids: 258.5;Late spermatids: 103.6;Spermatocytes: 204.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 7.9;JURKAT: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA030799 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA030799: AB_10601337" "unprognostic (5.94e-3)" "unprognostic (6.00e-2)" "unprognostic (6.49e-3)" "unprognostic (1.63e-1)" "unprognostic (6.62e-2)" "unprognostic (2.78e-1)" "unprognostic (2.27e-2)" "unprognostic (2.27e-1)" "unprognostic (8.17e-2)" "unprognostic (2.44e-1)" "unprognostic (1.12e-3)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (1.88e-2)" "unprognostic (4.65e-2)" 1.6 0.7 0.5 0.7 0.5 0.1 0.7 0.6 0.7 0.2 1.2 0.3 0.2 0.2 0.3 0.1 2.1 0.4 0.3 0.4 0.6 2.0 0.9 0.3 0.7 0.7 0.8 0.3 0.2 1.2 0.5 0.2 0.7 0.4 0.2 0.5 0.7 0.4 0.1 0.1 0.2 0.0 0.6 0.4 0.3 20.4 0.7 1.0 1.5 0.5 0.6 0.2 0.1 0.7 0.2 1.0 0.1 0.4 1.0 0.4 0.6 0.6 0.4 0.8 0.9 0.1 1.4 1.4 1.2 0.1 7.9 0.1 2.1 2.0 1.0 3.5 0.0 1.3 0.3 0.7 0.1 2.3 0.7 0.7 1.0 1.4 0.5 0.3 0.4 4.8 1.1 1.9 1.4 0.0 0.9 0.3 1.1 2.5 0.6 1.1 0.8 1.4 1.2 0.1 1.0 0.7 0.1 0.1 3.1 0.2 0.9 1.3 0.1 0.1 0.7 0.5 1.2 2.0 0.7 1.1 1.5 0.2 1.1 0.0 0.0 0.8 0.9 0.5 1.1 1.6 1.0 1.1 0.1 0.7 0.9 1.3 0.0 0.4 0.1 0.4 1.6 0.3 0.5 0.5 0.6 0.7 0.4 0.6 0.7 0.8 0.7 0.6 0.7 0.7 1.0 0.0 1.5 2.0 2.8 1.1 1.2 4.0 0.0 1.0 2.0 2.8 1.2 2.8 2.6 0.0 4.2 1.7 0.5 0.3 13.7 1.5 258.5 21.6 0.8 0.8 3.0 0.4 4.1 1.7 1.5 0.3 0.0 1.5 0.0 3.2 0.7 1.8 1.3 0.0 3.9 0.6 0.0 0.6 0.2 103.6 1.8 0.5 0.0 1.9 0.8 1.2 2.1 2.0 4.0 0.9 0.1 1.5 0.6 0.9 0.1 6.3 36.0 0.7 0.0 0.2 1.5 204.8 31.3 0.0 0.1 0.3 1.5 3.6 0.7 1.2 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 502.2;Excitatory neurons: 92.0;monocytes: 133.1;Oligodendrocyte precursor cells: 256.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cell line enhanced" "Detected in some" "A549: 4.6;ASC TERT1: 5.6;BJ hTERT+: 3.2;RPTEC TERT1: 7.8;T-47d: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 4.8 3.1 1.1 10.1 1.9 9.0 2.6 0.9 2.1 5.1 1.2 4.3 0.6 4.8 1.9 7.0 4.1 6.2 3.9 1.3 1.1 10.9 5.6 52.4 6.8 1.7 1.1 5.4 3.6 8.4 2.1 1.2 1.4 2.6 1.8 1.5 3.5 2.0 5.5 2.1 3.6 4.0 1.1 10.8 2.1 0.8 1.2 2.5 2.9 7.9 5.4 4.5 5.5 1.9 0.0 4.6 0.0 0.0 2.3 5.6 0.0 1.3 3.2 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.4 0.0 2.1 0.4 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.3 0.0 0.5 2.7 0.1 3.1 1.5 1.0 0.4 0.5 0.6 0.4 0.0 0.0 0.0 1.3 0.0 1.7 0.0 7.2 2.2 0.0 5.2 0.0 1.8 0.0 0.0 2.1 1.7 0.0 0.0 58.2 0.0 6.9 0.3 0.0 1.3 1.1 1.9 0.9 2.1 1.3 1.1 1.7 1.1 1.4 1.1 1.2 1.9 7.4 32.1 502.2 17.3 29.9 2.4 1.8 0.4 2.8 8.6 1.3 1.4 7.8 5.7 17.3 27.6 0.0 0.0 1.9 0.0 1.9 1.3 0.5 0.4 2.6 7.0 0.0 2.1 92.0 2.7 0.1 16.1 0.5 0.4 13.9 2.7 13.2 8.2 4.6 47.1 28.0 0.0 0.0 55.8 8.7 1.2 19.0 52.2 12.4 73.1 133.1 8.6 3.1 256.9 3.1 0.8 1.1 12.0 2.8 0.6 0.0 22.5 3.4 1.0 0.0 22.5 4.8 0.3 1.0 12.6 3.1 0.4 3.4 11.2 0.0 0.7 LSAMP "IGLON3, LAMP" ENSG00000185565 "Limbic system associated membrane protein" Q13449 3 115802363-117139389 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.9;retina: 41.3" "Group enriched" "Detected in many" 9 "Astrocytes: 3381.0;Excitatory neurons: 1001.8;Inhibitory neurons: 2137.4;Oligodendrocyte precursor cells: 2480.6;Oligodendrocytes: 933.9" "Cancer enhanced" "Detected in many" "glioma: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 11.0;SH-SY5Y: 22.5;WM-115: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054051, HPA076122" Enhanced Cytosol NA NA 150000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA054051: AB_2682358, HPA076122: AB_2686779" "unprognostic (4.18e-2)" "unprognostic (2.54e-1)" "unprognostic (9.97e-3)" "unprognostic (6.03e-2)" "unprognostic (9.63e-2)" "unprognostic (4.15e-3)" "unprognostic (6.81e-2)" "unprognostic (2.70e-2)" "unprognostic (5.71e-2)" "unprognostic (6.82e-3)" "unprognostic (1.26e-1)" "unprognostic (6.03e-2)" "unprognostic (1.92e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (5.23e-5)" "unprognostic (1.31e-2)" 3.1 15.7 47.8 5.6 45.4 1.0 1.7 22.6 73.9 21.8 0.0 9.9 2.0 5.0 3.1 3.9 3.1 13.5 2.3 64.2 36.3 2.6 0.8 10.6 4.9 37.5 32.2 5.5 14.4 8.9 3.8 1.0 37.8 26.1 3.8 41.3 1.2 7.3 0.2 5.1 2.6 3.8 28.5 1.9 3.8 4.6 56.4 1.2 5.0 0.2 6.7 6.5 4.8 31.9 0.2 3.2 11.0 0.3 1.1 3.4 1.1 1.0 0.5 0.4 1.1 0.2 0.7 0.8 0.2 6.0 0.3 0.2 0.2 0.1 0.5 0.5 0.1 0.3 1.0 0.3 0.2 0.8 0.5 2.8 0.0 1.3 0.1 0.2 0.1 1.3 0.4 1.2 0.0 0.3 1.3 0.8 4.1 0.1 0.9 0.2 0.2 0.2 2.8 1.1 2.4 22.5 0.0 0.2 3.5 4.5 0.3 0.8 0.0 2.0 1.5 2.7 0.6 1.3 1.2 0.3 0.4 0.3 55.9 0.9 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.1 0.4 0.0 0.1 0.1 0.1 0.0 47.8 45.4 22.6 73.9 64.2 36.3 37.5 32.2 37.8 28.5 56.4 31.9 0.5 0.0 1.1 3381.0 0.6 7.6 0.3 0.0 0.0 54.2 1.2 0.4 25.5 4.3 0.6 0.0 2.1 0.2 0.0 0.0 0.0 0.0 22.5 0.9 26.5 5.8 0.0 0.0 1001.8 3.6 0.0 25.0 2.6 1.1 0.0 20.1 4.2 0.0 0.3 220.4 2137.4 0.0 0.0 0.0 3.2 22.2 126.2 1.9 56.9 111.5 0.0 126.9 0.0 2480.6 933.9 0.4 0.0 91.7 1.0 18.3 0.0 0.2 0.0 11.3 0.0 0.1 4.0 0.9 0.5 0.6 5.1 0.0 0.4 4.9 0.0 0.6 LSS OSC ENSG00000160285 "Lanosterol synthase" P48449 21 46188141-46228824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Isomerase "Cataract, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 132.0;Oligodendrocytes: 158.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 234.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032060, HPA032062, CAB034116" Supported NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB034116: AB_2138611, HPA032060: AB_10671085, HPA032062: AB_2674134" "unprognostic (2.78e-3)" "unprognostic (8.53e-3)" "unprognostic (6.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.92e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.07e-4)" 29.3 38.9 20.0 10.8 30.8 5.7 22.3 38.9 33.5 20.8 7.1 22.9 28.5 26.6 12.1 39.7 18.0 9.0 25.1 15.7 26.2 10.7 54.8 24.1 9.4 62.3 40.7 30.3 19.4 12.2 25.9 8.0 65.7 24.0 10.7 6.8 16.1 12.4 29.0 27.6 17.4 12.2 28.4 7.6 23.3 17.5 40.4 12.3 10.2 19.5 8.0 20.2 19.6 58.7 70.4 22.2 70.9 30.6 94.1 90.6 20.3 26.8 186.4 32.1 62.7 73.9 54.4 15.4 22.3 51.7 234.6 32.7 63.2 110.9 12.9 14.9 34.5 37.7 38.6 48.3 85.5 13.7 25.1 89.0 41.4 59.7 25.6 22.2 26.9 72.1 37.4 87.3 27.8 23.8 29.9 19.7 115.4 11.3 20.1 34.9 21.9 92.2 82.8 38.1 41.4 36.7 31.4 24.0 27.5 30.6 38.0 33.7 40.8 37.9 30.2 33.8 21.1 31.8 29.5 30.6 39.7 59.4 16.6 4.6 2.1 2.2 4.0 1.8 2.8 3.1 2.9 4.9 2.4 1.5 2.4 3.6 0.0 1.7 1.5 5.0 1.4 3.6 20.0 30.8 38.9 33.5 15.7 26.2 62.3 40.7 65.7 28.4 40.4 58.7 13.8 12.8 36.8 66.6 7.2 37.0 3.8 30.2 8.0 16.0 15.3 8.0 13.7 14.3 18.7 11.0 4.2 3.7 11.8 10.4 0.0 10.5 6.5 6.6 16.4 10.3 19.7 16.8 21.2 17.2 6.7 19.7 13.3 14.6 3.8 20.6 11.4 132.0 9.7 23.5 24.2 11.6 16.2 7.5 13.7 6.6 21.1 4.9 21.4 21.5 12.0 7.5 5.2 22.1 158.8 14.0 2.7 13.5 6.3 16.2 5.0 4.1 11.0 16.4 0.0 9.8 8.5 20.3 18.1 12.6 54.0 6.3 7.9 18.0 10.9 4.6 LTA "LT, TNFB, TNFSF1" ENSG00000226979 "Lymphotoxin alpha" P01374 6 31572054-31574324 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 1.9;lymphoid tissue: 5.6;testis: 4.2" "Group enriched" "Detected in some" 4 "B-cells: 13.7;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.2;MOLT-4: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA007729 Uncertain "Secreted to blood" NA NA 8150 "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA007729: AB_1852906" "unprognostic (3.76e-2)" "unprognostic (1.48e-2)" "unprognostic (1.36e-3)" "unprognostic (8.99e-5)" "unprognostic (3.22e-1)" "unprognostic (5.13e-3)" "unprognostic (2.07e-1)" "unprognostic (4.71e-2)" "unprognostic (3.10e-2)" "unprognostic (3.39e-4)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (8.72e-12)" "unprognostic (2.59e-1)" "unprognostic (5.49e-2)" "unprognostic (4.30e-2)" "unprognostic (3.03e-1)" 0.2 0.0 0.1 0.6 0.1 0.8 0.1 0.2 0.2 0.2 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.4 2.4 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.1 1.9 0.0 0.1 5.6 0.1 4.2 0.1 0.0 0.2 0.0 2.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.0 1.1 2.3 13.7 0.1 0.1 0.0 0.6 0.6 0.5 1.3 2.5 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 1.9 0.0 0.0 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.3 0.4 0.4 0.0 0.3 0.0 1.0 0.4 0.0 1.0 2.5 2.4 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.3 1.8 0.5 0.5 0.4 0.0 14.5 0.1 0.0 0.0 LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 66.7;lymphoid tissue: 229.2" "Cell type enhanced" "Detected in many" "B-cells: 1087.8;dendritic cells: 183.5;Ductal cells: 280.4;Pancreatic endocrine cells: 296.2;T-cells: 554.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.6;Daudi: 127.4;HDLM-2: 82.2;HMC-1: 38.1;NB-4: 62.3;REH: 58.6;U-698: 90.8" "Not detected" "Not detected" HPA048884 Approved Approved Centrosome NA NA "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA048884: AB_2680543" "unprognostic (1.43e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "prognostic favorable (2.36e-6)" "unprognostic (2.91e-3)" "prognostic favorable (1.74e-4)" "unprognostic (1.45e-1)" "unprognostic (9.49e-3)" "unprognostic (1.42e-3)" "unprognostic (4.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (8.91e-2)" "unprognostic (4.92e-2)" "unprognostic (6.56e-3)" "unprognostic (1.99e-1)" 3.5 0.7 0.2 82.6 0.3 19.1 1.3 0.1 0.5 1.3 0.2 6.7 8.2 1.2 0.0 4.3 1.2 4.8 1.1 0.1 0.2 10.3 4.8 8.7 103.9 0.4 0.2 0.4 2.5 0.2 0.7 0.9 0.3 2.4 2.7 0.0 4.2 0.3 1.0 2.2 66.7 1.9 0.2 229.2 13.9 0.2 0.3 83.3 3.8 1.4 47.6 8.7 1.4 0.2 18.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 35.6 127.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 82.2 0.0 1.4 0.0 0.0 0.0 0.4 38.1 0.0 0.0 0.0 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 18.5 62.3 0.0 0.0 0.0 58.6 0.0 11.4 32.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.7 0.0 0.0 0.5 0.0 0.0 0.0 0.8 90.8 0.0 0.0 0.0 79.2 9.2 542.5 95.7 55.9 646.7 1027.3 924.3 419.4 14.5 1021.9 713.6 317.0 327.8 142.5 94.5 412.0 672.0 308.9 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.2 0.3 0.2 0.3 0.2 3.0 0.0 9.0 1.3 1087.8 16.3 0.5 45.7 2.2 0.7 2.9 3.7 0.5 2.8 4.7 90.1 0.0 0.9 183.5 0.9 1.9 280.4 3.5 2.2 2.0 8.4 0.0 11.2 0.9 113.1 0.3 6.3 3.1 1.5 14.0 0.1 10.8 3.5 10.1 0.0 0.9 0.4 160.7 31.0 112.1 0.2 0.6 49.8 42.7 0.0 72.3 1.8 99.9 0.0 0.3 296.2 1.6 0.0 13.6 3.0 0.0 11.6 0.9 0.2 6.6 1.3 4.3 0.4 1.2 1.2 12.4 0.3 554.0 0.3 3.6 0.3 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LVRN "APQ, AQPEP, FLJ90650, TAQPEP" ENSG00000172901 Laeverin Q6Q4G3 5 115962454-116027619 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 11.1;placenta: 21.8" "Group enriched" "Detected in some" 4 "Early spermatids: 29.3;Extravillous trophoblasts: 33.1;Late spermatids: 68.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 2.5" HPA053254 Enhanced "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 50: Fibroblasts - ECM organization" "HPA053254: AB_2682092" "unprognostic (1.47e-1)" "unprognostic (3.38e-3)" "unprognostic (5.81e-2)" "unprognostic (2.97e-3)" "unprognostic (5.38e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-3)" "unprognostic (1.88e-2)" "unprognostic (2.23e-1)" "unprognostic (2.23e-2)" "unprognostic (3.83e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-7)" "unprognostic (1.05e-2)" "unprognostic (5.94e-2)" "unprognostic (6.53e-2)" "unprognostic (3.31e-2)" 11.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 21.8 0.0 0.0 0.4 0.0 0.2 0.1 0.3 0.4 0.8 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 1.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 29.3 0.0 0.1 0.1 0.0 0.0 2.1 0.0 33.1 7.9 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 68.1 4.7 0.3 0.0 1.9 0.0 0.0 0.0 3.0 1.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.3 0.3 0.1 0.0 10.7 0.0 1.0 0.0 0.1 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Mental retardation, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 407.6;Hofbauer cells: 273.6;Inhibitory neurons: 378.7;Kupffer cells: 394.7;Proximal enterocytes: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Group enriched" "Detected in some" 13 "Karpas-707: 207.0;RPMI-8226: 355.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" 27.8 15.4 14.6 20.7 14.5 4.0 17.3 10.3 13.5 35.0 14.2 11.4 70.3 23.5 6.0 22.6 20.1 16.7 6.8 13.7 13.0 48.2 25.7 18.8 30.9 19.0 22.6 39.2 3.2 50.8 5.3 36.1 17.6 18.4 10.7 4.7 11.8 15.4 49.6 57.8 83.0 17.8 18.7 26.0 13.0 10.0 28.7 17.9 23.1 19.8 23.9 17.7 30.5 29.8 0.0 0.0 22.4 0.0 0.8 0.0 0.5 2.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.0 0.8 0.7 0.4 0.0 7.2 8.3 0.0 0.0 0.2 1.0 0.1 14.3 0.1 6.4 0.0 0.2 0.0 0.0 0.3 2.4 207.0 1.5 0.1 0.2 0.4 13.5 0.0 0.0 0.1 6.2 355.1 0.0 1.9 0.5 0.3 0.9 0.2 0.6 8.7 0.2 0.0 4.5 0.0 6.9 0.5 0.9 0.0 0.0 0.0 0.9 0.0 1.4 38.1 0.3 0.0 1.1 1.1 8.6 0.0 3.2 2.7 0.1 0.0 0.2 0.5 0.0 0.9 0.3 0.0 4.7 0.6 14.6 14.5 10.3 13.5 13.7 13.0 19.0 22.6 17.6 18.7 28.7 29.8 40.2 9.6 14.6 24.8 10.4 88.3 3.7 30.1 51.2 9.7 8.5 33.1 8.2 57.2 7.7 3.7 0.0 1.7 71.5 18.2 11.7 1.7 1.1 8.1 114.1 42.7 3.0 8.4 5.1 0.8 3.0 73.0 12.8 6.6 22.1 73.0 407.6 63.7 273.6 0.0 378.7 8.9 16.2 394.7 57.9 9.0 149.8 127.2 44.4 122.7 2.7 78.1 40.2 67.3 20.0 4.0 9.9 115.1 48.1 33.9 288.9 146.6 3.0 2.7 13.1 42.7 40.0 1.1 2.0 107.4 141.2 4.2 122.2 28.0 10.1 5.4 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MAGEH1 APR1 ENSG00000187601 "MAGE family member H1" Q9H213 X 55452127-55453566 "Predicted membrane proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "epididymis: 515.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011324, HPA011971" Uncertain Supported "Nucleoli,Nucleoli rim" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli, Nucleoli rim" "HPA011324: AB_1853499, HPA011971: " "unprognostic (2.50e-1)" "unprognostic (3.01e-1)" "unprognostic (4.07e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.95e-2)" "unprognostic (8.50e-2)" "unprognostic (1.13e-2)" "unprognostic (9.93e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "prognostic favorable (2.60e-4)" "unprognostic (6.37e-2)" "unprognostic (1.81e-2)" "unprognostic (1.29e-3)" "unprognostic (1.90e-1)" "unprognostic (3.95e-2)" "unprognostic (2.52e-1)" 20.2 29.9 46.8 17.6 48.2 5.1 18.4 40.9 59.3 29.6 59.4 21.0 10.2 30.9 515.9 10.0 45.3 18.1 24.1 47.1 60.0 25.5 19.6 23.5 22.7 41.9 47.7 36.3 28.1 25.5 54.1 20.9 45.7 48.8 11.5 22.0 18.6 44.3 12.9 11.3 17.1 27.3 45.5 20.4 25.3 33.8 50.3 32.0 28.6 16.9 17.0 17.9 16.7 48.8 0.1 5.7 32.6 0.0 51.5 31.0 0.4 36.0 32.9 9.7 26.0 0.1 7.4 0.0 48.2 36.4 18.4 4.9 12.5 13.5 15.2 42.5 2.0 11.4 0.0 4.6 17.0 0.6 14.1 25.8 1.2 5.6 4.1 9.1 15.0 12.0 6.5 43.8 10.8 22.0 30.8 9.8 9.3 0.0 6.8 19.1 4.1 24.0 17.9 0.0 0.2 24.5 0.0 9.5 15.5 24.4 4.7 8.5 17.7 13.3 15.4 8.2 1.9 25.9 35.1 4.9 24.8 15.8 17.2 14.0 9.0 20.5 21.5 14.3 19.4 18.9 35.4 24.6 13.7 17.9 48.2 30.5 1.2 18.9 18.5 28.5 52.1 19.0 46.8 48.2 40.9 59.3 47.1 60.0 41.9 47.7 45.7 45.5 50.3 48.8 24.9 6.4 14.4 4.9 18.3 8.0 7.8 20.0 5.2 36.7 8.0 14.1 10.4 18.6 12.5 12.9 10.4 2.8 15.7 1.9 13.7 32.2 1.6 2.8 33.5 29.0 15.8 3.0 14.2 10.7 2.0 42.9 3.1 1.9 12.7 11.1 32.9 14.0 15.0 37.0 17.5 8.4 4.1 3.8 11.2 4.0 47.2 6.2 21.4 6.5 9.3 56.8 23.7 18.6 28.4 4.7 8.8 63.9 39.8 13.7 0.8 20.1 6.7 19.6 26.3 44.5 35.0 1.4 2.7 3.3 6.3 1.6 19.9 19.7 4.6 4.8 MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 74.5" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 37.0;Fibroblasts: 38.7;Inhibitory neurons: 42.9;Leydig cells: 96.6;Microglial cells: 45.9;Peritubular cells: 82.0;Sertoli cells: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.7;HHSteC: 57.2;LHCN-M2: 75.0;TIME: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" 17.2 8.2 1.0 1.2 1.2 0.2 15.6 0.8 1.6 30.4 2.3 45.5 8.4 74.5 19.1 21.2 58.5 13.0 15.4 0.7 1.5 2.6 1.2 37.2 0.5 0.7 1.2 49.1 3.7 1.8 0.8 4.3 0.7 7.7 12.3 5.7 9.9 10.8 6.6 9.2 21.6 25.3 0.7 16.1 19.1 7.5 1.8 1.6 8.0 17.1 3.1 32.3 18.5 1.1 0.3 0.0 0.7 0.0 55.7 18.8 1.7 11.1 5.0 2.7 4.6 0.0 1.2 0.0 0.7 2.1 1.5 9.1 0.1 0.8 2.3 0.0 0.0 0.0 15.6 0.1 57.2 0.0 0.0 3.6 0.7 1.7 0.9 19.9 4.9 0.0 0.0 0.5 75.0 0.0 0.0 0.1 7.7 0.1 0.0 0.0 8.8 7.3 24.6 0.0 0.7 0.0 0.1 0.1 0.0 20.8 0.0 0.0 71.0 0.0 1.8 0.1 2.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.6 0.7 1.5 0.7 1.2 0.7 0.7 1.8 1.1 2.0 0.0 1.5 20.2 0.5 6.1 0.5 0.4 0.6 0.8 0.5 10.8 4.3 0.0 0.1 3.7 4.2 0.2 0.2 0.2 0.0 0.1 42.5 0.7 13.7 3.9 0.0 0.0 37.0 0.2 6.6 38.7 0.5 0.5 1.3 0.3 0.4 0.0 3.3 0.0 42.9 0.1 0.0 0.0 17.5 11.4 96.6 13.6 10.6 45.9 0.0 13.8 0.0 11.6 23.3 0.4 0.2 82.0 0.0 0.1 0.0 0.5 0.1 0.5 39.5 4.8 22.4 0.4 0.4 1.1 4.8 0.3 0.8 0.1 0.1 0.1 MAN2B2 KIAA0935 ENSG00000013288 "Mannosidase alpha class 2B member 2" Q9Y2E5 4 6575189-6623362 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 15000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "unprognostic (1.30e-1)" "unprognostic (3.32e-1)" "unprognostic (1.28e-1)" "prognostic favorable (7.59e-4)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "unprognostic (6.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-3)" "unprognostic (2.18e-1)" 20.0 13.6 12.9 13.8 18.2 14.8 16.4 7.7 14.3 17.6 26.0 14.5 13.4 18.6 14.1 11.3 17.7 15.9 22.6 13.2 15.6 15.1 23.7 18.2 13.5 13.0 13.2 26.6 22.0 9.2 17.9 12.9 11.8 18.0 7.9 5.2 16.7 11.5 4.7 13.6 15.8 10.3 10.6 17.7 20.1 4.4 15.0 9.0 23.2 4.7 8.5 19.3 15.9 11.9 17.5 15.6 2.9 21.0 44.7 30.9 19.7 35.0 40.5 16.8 22.9 9.0 32.3 8.7 16.5 38.2 39.2 17.4 1.0 11.1 9.2 10.4 8.8 11.7 10.9 10.2 19.5 22.0 51.8 41.0 10.9 13.4 3.6 30.3 19.7 10.8 5.1 21.9 22.1 10.8 10.9 13.9 3.8 21.8 11.9 10.7 14.4 10.4 8.8 17.4 5.0 5.5 23.4 13.9 8.9 10.0 27.7 29.1 36.3 30.3 9.1 38.2 22.5 9.0 8.4 4.2 35.4 25.5 26.7 15.4 9.0 14.3 11.7 13.2 8.9 4.2 7.0 10.7 8.6 4.4 6.3 8.2 11.0 6.8 17.5 3.3 10.7 11.0 12.9 18.2 7.7 14.3 13.2 15.6 13.0 13.2 11.8 10.6 15.0 11.9 9.8 16.0 18.9 7.8 11.6 5.0 5.5 4.9 11.4 8.9 8.2 5.6 17.0 20.0 11.1 11.0 6.2 13.5 12.9 18.3 1.9 9.7 0.6 18.7 15.8 8.2 7.8 5.7 9.4 10.7 10.2 18.4 11.7 36.8 10.8 11.1 17.5 44.1 20.9 10.1 8.3 11.0 2.0 30.2 8.2 1.1 19.6 18.0 3.6 8.4 11.2 13.0 5.2 6.0 8.9 10.1 9.0 24.5 15.1 7.1 11.7 4.2 9.5 7.4 13.1 7.5 8.5 1.1 0.6 8.0 3.8 8.5 15.6 4.4 8.9 4.6 MAOA ENSG00000189221 "Monoamine oxidase A" P21397 X 43654907-43746824 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" Oxidoreductase "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 230.3" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 819.8;Proximal tubular cells: 569.9;Undifferentiated cells: 285.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 162.1;HHSteC: 302.9;HSkMC: 76.1;hTCEpi: 87.2;RT4: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009437, HPA054807, HPA059299" Enhanced Supported Mitochondria,Cytosol No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Cytosol "CAB009437: AB_2137260, HPA054807: AB_2682607, HPA059299: AB_2683970" "unprognostic (9.54e-3)" "unprognostic (1.63e-1)" "unprognostic (7.99e-2)" "unprognostic (3.07e-1)" "unprognostic (6.75e-2)" "unprognostic (3.32e-1)" "unprognostic (9.51e-2)" "unprognostic (6.89e-3)" "unprognostic (2.21e-1)" "unprognostic (4.29e-2)" "unprognostic (3.94e-1)" "unprognostic (3.54e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (4.04e-2)" "unprognostic (2.98e-3)" 143.9 27.7 24.7 8.6 27.6 0.4 71.6 26.5 26.6 26.6 13.9 116.4 163.4 24.0 14.1 46.7 39.1 16.9 49.6 22.3 31.7 76.9 119.1 63.5 2.4 26.9 32.5 40.7 39.1 31.4 4.0 30.2 56.4 46.3 117.9 28.2 77.3 35.0 33.5 37.4 230.3 24.0 21.3 6.3 55.9 3.7 41.4 9.9 118.4 34.3 5.3 65.0 38.8 19.0 0.0 3.7 0.6 9.9 162.1 0.0 0.6 0.2 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 4.6 17.2 6.1 22.3 0.1 0.0 2.5 6.9 0.5 18.6 302.9 0.0 16.9 76.1 87.2 0.2 45.2 0.1 20.0 0.0 0.3 0.4 5.7 2.9 0.1 0.8 1.6 20.7 5.0 0.0 0.3 0.5 22.3 131.8 3.1 7.8 0.0 0.0 0.3 0.4 0.5 0.0 8.7 0.0 8.2 0.7 0.0 0.3 0.0 0.0 9.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.7 27.6 26.5 26.6 22.3 31.7 26.9 32.5 56.4 21.3 41.4 19.0 35.2 70.5 146.9 23.2 4.6 11.0 177.7 32.3 116.7 5.0 13.6 10.2 101.3 94.4 49.3 60.7 22.9 11.5 0.2 248.0 121.3 36.7 25.2 50.4 42.5 43.6 38.0 4.8 4.0 13.4 21.3 24.3 40.2 175.1 5.7 7.3 53.6 193.7 6.6 3.3 5.0 137.5 67.1 12.2 2.1 33.9 5.6 6.7 10.6 21.5 17.1 25.4 0.0 7.5 1.3 49.5 140.5 0.0 2.6 64.6 819.8 569.9 32.8 27.4 6.6 4.4 30.5 1.3 0.8 120.6 14.3 207.0 3.7 3.5 285.1 129.0 MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 325.5" "Cell type enhanced" "Detected in many" "dendritic cells: 90.9;Horizontal cells: 299.5;Peritubular cells: 76.3" "Cancer enhanced" "Detected in many" "glioma: 18.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Cell line enhanced" "Detected in many" "ASC diff: 60.7;BJ hTERT+: 61.8;fHDF/TERT166: 94.0;hTEC/SVTERT24-B: 58.1;U-87 MG: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039063, HPA039064, HPA066488" Enhanced Approved Cytosol No No 55000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA039063: AB_2676327, HPA039064: AB_10673302, HPA066488: AB_2685676" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.86e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-2)" "unprognostic (5.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-2)" "unprognostic (1.13e-3)" "unprognostic (8.36e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (6.59e-5)" "unprognostic (5.83e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (1.09e-5)" "prognostic unfavorable (1.66e-5)" 7.2 6.0 65.3 3.8 78.6 0.9 4.4 39.5 325.5 8.0 0.0 16.5 1.2 8.2 2.4 3.0 7.2 4.2 15.5 92.8 37.5 1.2 0.2 2.2 1.0 201.4 41.4 5.0 1.0 2.0 11.7 2.7 186.0 4.8 3.5 21.7 2.5 7.5 4.5 3.2 4.0 13.1 22.5 0.9 4.3 3.8 85.8 24.0 4.1 5.1 0.9 11.9 4.5 156.7 0.3 2.5 11.1 6.4 60.7 41.5 0.1 36.3 61.8 10.5 10.1 4.4 0.1 0.2 15.3 94.0 3.3 0.5 15.0 0.1 6.1 5.5 1.4 14.2 3.5 0.3 5.8 0.4 5.8 31.3 0.1 58.1 0.3 15.8 8.0 41.3 24.0 0.3 42.8 0.5 26.6 0.8 8.1 0.0 1.0 7.2 32.1 0.1 0.2 0.1 34.8 10.6 1.2 0.1 0.3 14.6 2.3 0.6 1.5 33.7 11.3 11.3 0.5 0.0 1.6 5.0 121.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.1 0.1 65.3 78.6 39.5 325.5 92.8 37.5 201.4 41.4 186.0 22.5 85.8 156.7 6.7 3.2 1.1 11.8 2.2 5.5 1.4 1.4 2.8 43.4 1.7 3.6 55.1 0.0 7.9 3.7 25.0 0.3 90.9 1.0 0.0 0.4 13.1 33.2 19.5 5.7 11.4 3.0 34.4 0.0 0.6 46.9 2.6 1.0 7.0 16.7 4.2 0.0 2.4 299.5 45.1 1.7 10.2 0.3 7.4 5.6 51.0 9.4 8.8 12.2 0.7 16.7 0.0 9.5 51.4 0.7 0.0 76.3 1.1 0.5 0.0 0.5 63.6 27.2 32.9 45.7 48.2 10.6 25.6 1.1 4.1 1.1 5.6 3.1 1.4 0.5 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MAP4 ENSG00000047849 "Microtubule associated protein 4" P27816 3 47850690-48089272 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 743.9" "Cell type enhanced" "Detected in all" "Bipolar cells: 392.2;Cardiomyocytes: 921.5;Cone photoreceptor cells: 625.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038149, HPA038150" Enhanced Approved "Plasma membrane,Microtubules,Cytosol" NA NA 880000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "Plasma membrane" "HPA038149: AB_10672471, HPA038150: AB_10672505" "unprognostic (2.51e-1)" "unprognostic (4.48e-1)" "unprognostic (2.72e-1)" "unprognostic (1.95e-2)" "unprognostic (3.36e-1)" "unprognostic (4.57e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.82e-2)" "unprognostic (1.46e-2)" "unprognostic (5.02e-2)" "unprognostic (2.23e-2)" "unprognostic (1.30e-2)" "unprognostic (2.25e-2)" "unprognostic (8.89e-2)" "unprognostic (6.45e-2)" "unprognostic (1.88e-1)" "unprognostic (1.21e-3)" 127.4 55.7 475.5 50.4 483.4 16.1 98.0 433.2 406.8 118.0 215.5 193.2 35.1 111.7 69.7 90.7 94.7 52.9 380.9 351.2 408.7 88.3 66.0 105.0 35.0 567.9 490.6 90.0 71.4 31.4 56.1 64.8 509.2 92.7 47.6 149.0 71.4 88.1 743.9 120.6 80.6 94.5 526.1 64.0 93.9 80.0 552.3 42.1 61.1 491.0 37.8 135.5 115.2 533.2 121.9 95.7 117.1 89.3 168.6 298.5 49.5 222.6 241.2 184.1 204.9 81.3 74.4 102.3 50.7 337.9 172.8 79.2 151.4 201.6 204.7 148.7 63.8 69.3 102.8 106.0 228.6 48.6 53.9 251.4 246.4 224.0 271.6 167.1 245.1 70.6 91.2 115.3 146.9 69.1 69.5 58.9 70.9 59.9 195.0 36.6 110.1 128.1 118.2 100.1 46.4 72.3 171.0 68.3 118.6 163.0 50.1 44.8 334.5 172.7 132.3 182.9 144.4 80.4 66.9 47.8 222.2 58.6 167.3 10.5 6.6 3.7 15.6 10.6 7.5 12.3 10.2 12.7 7.1 11.5 4.9 7.6 2.6 13.4 27.3 10.8 13.0 9.7 475.5 483.4 433.2 406.8 351.2 408.7 567.9 490.6 509.2 526.1 552.3 533.2 147.9 70.5 48.2 124.4 45.1 74.8 55.4 53.1 42.7 392.2 34.7 36.2 921.5 48.6 53.4 80.9 625.5 33.8 54.6 43.7 27.4 97.8 116.2 78.2 143.2 110.4 28.8 21.6 63.7 65.3 81.0 105.5 39.8 93.4 27.8 81.6 50.0 57.3 38.0 47.1 71.2 31.7 34.6 28.3 50.5 38.8 77.0 40.0 78.2 95.5 72.0 82.8 47.4 77.9 167.2 92.0 28.0 103.0 47.2 89.0 37.1 39.2 43.6 97.5 72.3 149.0 119.0 65.6 64.3 58.7 69.6 22.4 60.5 137.4 39.5 44.7 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 42.6;dendritic cells: 42.6;Langerhans cells: 27.8;Plasma cells: 30.4;Rod photoreceptor cells: 77.9;T-cells: 43.6" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 45.2;HDLM-2: 46.4;Karpas-707: 46.9;REH: 25.5;RPMI-8226: 29.8;U-266/70: 36.0;U-266/84: 38.2;U-698: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 2.7 1.5 0.6 14.6 0.7 9.2 1.7 0.7 1.2 1.6 0.7 5.0 2.7 1.3 0.8 2.8 1.8 2.3 1.7 0.7 0.8 2.7 3.0 6.2 32.2 1.0 0.8 0.9 1.2 0.2 1.8 1.8 0.9 2.5 2.3 16.1 2.8 0.5 0.8 1.9 30.1 0.9 0.8 56.9 3.1 1.5 0.9 13.1 3.2 0.2 29.3 2.9 2.1 0.9 0.2 0.3 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 45.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 46.4 0.3 9.8 0.1 0.1 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 21.3 0.2 46.9 0.1 0.3 11.0 12.0 1.4 0.3 0.1 25.5 0.1 29.8 0.0 0.0 0.4 0.1 0.1 0.2 0.1 0.3 0.2 10.8 0.1 0.1 0.3 0.1 0.1 36.0 38.2 57.8 0.0 13.5 0.1 2.9 4.9 2.0 18.9 9.4 17.4 22.7 15.8 20.1 23.9 15.5 8.6 12.1 0.5 6.1 5.7 22.2 22.2 12.1 0.6 0.7 0.7 1.2 0.7 0.8 1.0 0.8 0.9 0.8 0.9 0.9 0.7 3.2 4.9 0.3 42.6 2.3 0.2 0.4 1.2 6.7 0.7 1.0 0.9 0.0 0.6 0.0 12.5 0.2 42.6 0.1 0.0 0.0 0.0 0.3 0.2 1.6 0.0 5.5 0.7 0.2 0.3 1.5 2.0 0.3 15.8 0.4 1.1 1.1 2.6 1.7 1.0 0.1 0.0 8.8 27.8 0.2 0.0 11.6 3.6 1.9 10.3 11.5 15.5 1.0 0.5 0.0 0.0 0.0 30.4 0.3 0.0 0.2 0.0 77.9 0.0 1.0 0.4 0.7 6.4 0.6 1.0 0.1 43.6 0.3 0.3 0.1 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 472.1" "Cell type enhanced" "Detected in many" "Microglial cells: 337.3;Oligodendrocytes: 1134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavorable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 54.1 9.1 272.6 42.9 316.1 72.5 32.2 208.8 252.5 23.9 95.0 21.1 10.6 27.4 12.1 35.2 19.7 34.5 44.8 219.4 256.3 15.0 32.8 29.2 54.1 317.5 286.1 23.1 16.1 15.0 10.0 49.4 273.1 13.9 17.8 22.7 19.3 10.2 37.4 21.1 17.7 28.7 246.7 24.2 22.0 40.1 348.5 44.3 15.8 30.6 60.1 33.1 25.6 472.1 112.7 83.8 175.2 84.3 162.4 288.6 219.5 139.8 114.3 122.2 100.1 139.5 145.6 163.1 118.3 210.3 36.0 45.5 56.0 123.2 121.1 219.8 38.0 122.4 62.5 367.7 136.7 59.1 5.5 261.3 55.3 301.9 133.5 122.1 322.5 90.3 80.9 0.4 325.4 61.3 137.8 36.5 89.2 42.5 131.5 164.1 120.0 0.6 81.2 38.8 68.5 113.6 96.5 0.4 104.0 160.8 22.4 105.1 409.1 240.5 102.9 70.6 168.6 0.3 0.4 96.7 155.2 73.2 180.1 8.8 3.2 0.0 2.3 3.2 1.6 3.4 2.9 1.5 1.1 5.0 2.2 2.5 13.5 1.1 3.1 6.0 3.7 1.5 272.6 316.1 208.8 252.5 219.4 256.3 317.5 286.1 273.1 246.7 348.5 472.1 104.3 19.2 23.9 283.0 64.5 30.0 41.9 17.4 12.5 109.1 14.3 17.4 71.0 28.6 29.6 18.4 50.1 13.1 38.4 12.0 0.0 57.4 31.5 67.2 77.1 84.2 17.4 48.0 197.5 53.2 23.4 49.7 26.5 101.0 24.0 151.8 67.1 39.2 38.8 35.3 122.4 13.6 14.2 26.9 245.9 46.0 55.0 54.7 19.6 337.3 88.0 49.2 10.3 228.7 1134.5 128.1 12.0 17.3 18.0 72.1 5.3 6.3 22.9 10.4 52.6 65.2 73.3 29.0 82.1 24.3 24.6 7.8 38.4 17.2 14.4 40.4 MAP7D1 "FLJ10350, FLJ39022, PARCC1, RPRC1" ENSG00000116871 "MAP7 domain containing 1" Q3KQU3 1 36155579-36180849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 286.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028075 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "HPA028075: AB_10603778" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (5.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.52e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.49e-6)" "unprognostic (6.00e-3)" "unprognostic (2.05e-1)" "unprognostic (3.57e-2)" "unprognostic (1.88e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (8.56e-6)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (9.32e-3)" 67.9 23.2 41.7 41.5 60.7 36.2 47.1 50.7 52.2 38.9 0.4 84.1 18.9 50.0 3.9 48.8 34.8 28.8 122.4 40.8 43.5 21.8 7.7 53.2 25.0 74.7 58.2 24.8 14.7 12.5 36.5 24.0 78.4 39.5 9.4 13.0 33.5 28.2 286.0 71.6 31.4 34.0 23.3 33.5 39.3 12.6 67.3 22.6 33.1 106.5 17.6 62.1 41.2 96.2 104.8 60.3 92.7 58.9 55.6 41.9 68.3 102.3 102.8 105.4 92.5 33.9 104.6 43.8 85.7 93.5 57.7 112.3 38.3 139.1 34.4 74.9 34.4 29.7 42.5 13.2 87.3 44.0 73.3 73.4 38.6 142.6 87.8 81.5 72.9 59.8 29.1 65.3 59.3 21.0 81.6 37.2 84.7 14.7 33.5 83.8 68.4 41.5 53.0 35.7 35.7 68.6 58.7 32.3 79.6 49.7 21.6 30.9 138.3 123.6 94.4 105.5 140.6 64.4 20.6 52.5 105.8 29.7 75.9 0.1 0.4 0.4 0.3 0.2 0.4 0.0 0.2 0.2 0.2 0.1 0.5 0.2 1.4 0.1 0.1 0.2 0.1 0.0 41.7 60.7 50.7 52.2 40.8 43.5 74.7 58.2 78.4 23.3 67.3 96.2 40.6 44.8 14.4 12.1 26.5 143.1 147.3 18.4 47.8 35.4 44.0 26.3 172.6 17.2 17.9 23.9 10.4 48.3 58.2 39.9 17.6 43.3 36.9 32.1 38.6 46.7 10.1 16.2 17.4 27.4 111.3 48.0 29.6 60.1 12.7 56.3 30.7 9.7 69.9 48.8 35.1 14.9 10.2 40.6 125.3 77.1 30.7 65.1 32.0 9.4 35.9 32.3 75.2 9.5 62.3 66.1 29.2 47.8 53.2 98.5 63.0 14.3 10.0 39.8 19.7 51.6 55.8 17.6 16.1 62.7 141.8 130.2 59.8 17.0 19.5 157.6 MAPK10 "JNK3, p493F12, p54bSAPK, PRKM10" ENSG00000109339 "Mitogen-activated protein kinase 10" P53779 4 85990007-86594625 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 91.3" "Cell type enhanced" "Detected in many" "Astrocytes: 902.0;Excitatory neurons: 1018.9;Inhibitory neurons: 727.8;Late spermatids: 400.5;Oligodendrocyte precursor cells: 596.6;Oligodendrocytes: 302.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "AF22: 155.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022625 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB022625: " "unprognostic (2.46e-2)" "unprognostic (4.36e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (5.17e-2)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (4.82e-2)" "unprognostic (3.81e-2)" "unprognostic (4.45e-2)" "unprognostic (1.18e-3)" "unprognostic (3.02e-2)" "prognostic favorable (3.11e-4)" "unprognostic (1.92e-2)" "unprognostic (1.44e-1)" "unprognostic (6.22e-3)" "prognostic favorable (5.57e-4)" 26.1 15.6 45.2 5.1 61.6 14.5 7.4 25.4 91.3 17.5 23.5 5.7 3.6 14.5 18.8 9.8 15.8 13.8 6.9 60.4 24.9 20.4 3.2 8.6 5.2 29.0 36.2 14.7 7.4 10.3 25.5 4.3 31.4 22.4 5.4 18.3 4.7 24.2 2.6 4.6 5.1 15.5 24.9 7.4 6.6 26.4 39.2 3.4 20.5 4.2 4.6 14.0 18.4 55.6 2.9 4.9 155.0 4.8 4.1 3.6 5.6 3.2 2.9 2.7 1.2 3.3 4.4 7.1 5.1 1.9 3.8 9.4 1.8 4.2 4.3 4.9 4.0 5.7 7.3 4.6 3.6 2.7 3.1 4.1 1.9 3.7 5.0 5.5 3.5 4.8 5.2 27.9 1.7 3.5 4.4 3.1 8.8 0.7 3.2 4.9 4.0 2.5 10.7 16.9 9.2 8.4 3.3 5.9 2.2 5.0 8.8 3.3 7.5 6.3 6.4 3.0 2.7 8.2 5.1 4.4 9.9 3.5 3.8 3.3 0.7 1.2 0.8 0.7 1.0 1.3 0.7 1.0 0.6 1.1 1.0 1.4 4.4 1.2 0.7 1.2 1.2 0.9 45.2 61.6 25.4 91.3 60.4 24.9 29.0 36.2 31.4 24.9 39.2 55.6 4.3 22.4 33.8 902.0 1.6 0.8 15.7 5.5 4.0 26.1 3.2 3.7 1.6 8.6 12.8 22.0 6.2 0.3 0.1 0.0 11.7 2.4 219.5 61.1 25.1 1.3 2.4 0.0 1018.9 0.0 0.5 16.9 2.0 7.1 2.5 6.2 1.1 0.0 0.3 38.7 727.8 0.0 4.1 0.3 0.0 400.5 26.4 1.5 1.8 185.5 0.0 15.7 0.0 596.6 302.8 2.0 0.0 54.9 0.1 7.6 0.0 22.6 68.9 10.8 6.6 7.2 18.5 10.5 5.5 1.3 1.0 0.1 0.9 28.5 0.0 22.6 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261716 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 279.7;tongue: 120.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.1;Astrocytes: 22.9;Endothelial cells: 15.8;Hepatic stellate cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 31.6" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: AB_2682524" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 11.0 2.3 15.6 3.8 16.5 1.3 7.9 15.5 21.2 11.4 9.2 4.7 3.5 19.0 9.8 6.3 11.2 4.4 15.7 15.1 16.5 10.7 1.4 6.8 4.1 17.1 14.9 10.6 1.8 4.3 25.1 4.1 14.6 10.0 1.1 1.4 4.3 6.9 279.7 1.5 4.4 8.6 14.6 4.3 5.0 4.6 15.2 0.9 3.2 120.9 1.4 6.0 5.9 13.9 23.2 13.9 5.3 16.3 12.4 13.5 7.5 17.5 15.1 28.2 18.3 19.6 7.2 45.1 23.4 19.6 16.8 15.4 24.3 3.4 5.5 12.8 34.0 29.2 46.7 24.9 37.7 28.4 54.5 29.8 6.0 7.2 0.0 16.8 33.2 4.0 26.3 38.5 13.4 12.8 0.0 35.4 15.9 7.6 22.5 41.4 14.2 43.9 17.5 3.0 18.0 6.5 13.3 0.5 22.1 4.2 7.1 29.6 18.7 28.5 26.1 6.6 11.2 9.3 7.3 24.5 7.2 24.7 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.6 16.5 15.5 21.2 15.1 16.5 17.1 14.9 14.6 14.6 15.2 13.9 23.1 0.0 3.2 22.9 1.6 0.8 0.7 3.3 1.2 5.5 1.2 1.3 8.8 4.3 0.8 0.0 0.0 0.3 0.9 0.3 1.9 0.5 0.3 0.6 10.0 15.8 1.8 1.7 9.8 0.0 2.8 5.3 2.6 0.7 10.8 0.6 20.7 0.9 6.3 1.7 6.5 0.2 8.2 2.2 0.8 1.9 6.5 2.2 0.0 6.5 0.6 8.1 0.0 5.0 0.9 0.5 0.0 3.8 2.8 3.6 0.4 8.0 0.9 2.2 6.6 3.3 3.0 0.7 12.1 0.8 0.6 0.4 2.2 3.2 0.3 0.2 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 43.1;SuSa: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: AB_2673706" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 8.3 13.7 4.0 4.0 4.4 5.2 7.7 4.0 5.9 14.3 4.4 10.6 5.5 11.1 3.3 16.3 8.7 4.5 6.2 3.9 4.5 7.7 3.9 8.7 3.7 5.3 6.1 12.5 3.4 2.9 6.1 6.7 4.4 8.9 3.5 2.2 6.7 6.1 5.0 12.5 7.3 6.7 3.3 9.4 6.7 11.8 5.0 3.5 7.4 3.4 3.6 10.1 15.2 4.1 6.9 11.0 9.9 7.7 43.1 17.2 10.4 9.0 8.3 13.0 12.4 12.2 1.4 4.1 7.3 16.5 10.4 8.2 10.4 9.4 7.8 7.2 8.3 1.9 8.4 5.4 21.2 1.9 7.8 21.6 6.2 18.2 7.2 12.0 9.5 7.5 3.7 1.4 13.2 4.8 13.0 7.4 10.7 8.4 6.7 8.6 12.9 3.0 5.4 3.7 4.4 12.3 9.7 1.0 5.0 53.7 6.1 3.1 6.0 14.6 10.8 15.5 6.7 2.6 4.0 1.2 16.5 1.6 9.2 0.8 3.4 10.7 3.7 6.5 2.0 1.8 1.8 3.2 2.3 1.0 1.6 2.0 1.1 4.9 6.0 1.4 1.0 3.1 4.0 4.4 4.0 5.9 3.9 4.5 5.3 6.1 4.4 3.3 5.0 4.1 10.7 6.4 3.3 2.6 7.8 5.5 6.1 9.5 13.6 2.4 5.8 4.6 5.3 2.8 5.6 5.5 2.1 5.7 6.7 16.2 5.9 8.1 8.7 3.0 7.9 8.5 10.7 1.7 2.0 6.2 8.0 9.6 12.2 5.2 2.5 7.7 7.5 1.1 7.7 0.0 2.1 6.9 10.2 6.9 6.1 5.7 11.5 14.4 3.6 6.5 3.4 13.1 17.5 1.0 2.0 8.0 20.8 11.7 9.3 6.3 9.0 3.5 3.2 2.1 26.3 8.4 11.1 33.2 16.4 9.8 4.3 5.1 6.2 7.7 6.7 5.3 MARCHF2 "HSPC240, MARCH-II, MARCH2, RNF172" ENSG00000099785 "Membrane associated ring-CH-type finger 2" Q9P0N8 19 8413270-8439017 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.1;Cardiomyocytes: 42.3;Extravillous trophoblasts: 11.6;Hofbauer cells: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014063 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" Cytosol "HPA014063: AB_1853576" "unprognostic (1.15e-2)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.48e-4)" "prognostic favorable (1.05e-5)" "unprognostic (3.00e-1)" "prognostic favorable (8.29e-4)" "unprognostic (3.43e-2)" "unprognostic (6.95e-2)" "unprognostic (3.06e-3)" "unprognostic (2.32e-1)" "prognostic favorable (6.21e-4)" "unprognostic (2.01e-1)" "unprognostic (3.52e-1)" "unprognostic (1.01e-1)" "unprognostic (3.16e-1)" "unprognostic (9.91e-2)" "unprognostic (1.80e-2)" 65.7 33.0 102.2 20.3 101.5 29.4 49.8 99.5 106.6 24.2 66.4 96.2 15.7 34.4 53.9 32.4 27.1 15.3 101.1 90.9 94.3 35.6 59.1 41.9 19.5 113.7 102.5 15.8 19.2 15.3 30.5 19.8 106.0 40.8 14.0 9.1 25.5 28.8 89.5 34.5 31.4 30.1 109.2 51.2 32.9 18.9 105.1 14.2 47.9 48.6 14.5 49.8 26.1 96.7 11.4 14.2 6.3 29.5 37.9 12.6 10.7 12.3 14.7 9.5 9.8 7.0 5.5 4.4 34.8 26.7 12.6 8.1 8.2 17.5 7.3 22.7 20.3 34.2 6.6 15.9 20.5 5.0 49.6 14.7 20.1 9.2 8.1 13.9 38.2 17.8 4.9 24.5 7.5 21.5 7.0 16.7 13.3 14.0 34.2 11.0 2.0 11.4 22.4 13.9 3.1 17.7 0.8 12.9 24.2 21.5 10.2 10.8 38.9 13.3 8.4 44.5 10.4 21.7 28.2 5.0 21.6 10.2 10.7 52.6 18.5 31.3 10.6 28.6 10.8 7.2 10.6 8.6 13.1 7.3 7.2 9.6 23.4 7.9 25.7 51.8 14.9 17.4 102.2 101.5 99.5 106.6 90.9 94.3 113.7 102.5 106.0 109.2 105.1 96.7 23.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 8.1 9.9 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 11.6 7.7 0.0 0.0 0.0 0.0 0.0 0.0 66.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 5.7 1.5 0.0 0.0 0.0 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528136-220664461 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 73.8;Excitatory neurons: 171.3;Inhibitory neurons: 170.1;Oligodendrocyte precursor cells: 167.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 11.3;RT4: 33.7;SuSa: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favorable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 6.3 1.8 6.9 1.4 7.1 0.0 4.9 6.4 10.0 4.6 8.4 5.4 0.4 4.2 9.7 4.8 3.3 1.7 8.0 7.4 6.7 2.3 0.3 3.1 0.5 6.4 6.8 1.7 0.9 2.4 6.9 1.1 7.4 3.0 1.2 9.3 3.7 4.0 2.2 2.5 2.5 3.9 5.7 1.3 2.8 6.9 6.5 1.4 4.3 3.5 1.9 5.3 5.1 6.4 0.4 0.0 5.4 1.1 0.0 0.0 1.8 1.6 2.2 1.8 2.5 0.0 0.0 0.0 0.0 0.0 2.5 2.5 11.3 6.0 1.0 0.0 8.4 0.0 2.3 0.0 0.0 0.7 0.8 0.9 4.7 0.0 3.0 0.8 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 8.1 5.5 1.8 0.0 7.4 0.0 0.0 33.7 6.4 6.2 0.3 0.3 0.5 12.2 0.5 0.0 0.0 0.0 2.4 4.0 7.1 0.0 0.0 0.0 1.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.1 6.4 10.0 7.4 6.7 6.4 6.8 7.4 5.7 6.5 6.4 3.2 0.0 0.5 73.8 0.5 3.4 2.6 10.0 13.1 28.6 1.6 3.8 21.9 0.0 4.7 3.7 31.3 2.1 0.0 0.7 0.0 1.6 7.3 19.3 6.4 3.4 9.0 0.0 171.3 0.0 2.3 6.3 2.6 35.5 0.0 13.6 3.3 0.0 0.3 10.1 170.1 0.4 4.1 0.3 1.5 3.6 2.1 0.2 0.0 15.0 0.0 12.3 0.0 167.9 45.9 0.1 0.0 6.4 0.6 4.8 1.5 0.2 4.1 11.9 0.0 6.9 17.5 17.4 5.1 13.1 3.3 1.0 0.4 1.1 0.9 4.8 MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 150.1;Intestinal goblet cells: 68.2;Paneth cells: 102.9;Proximal enterocytes: 199.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 21.7;BEWO: 30.9;CACO-2: 23.6;CAPAN-2: 22.5;HaCaT: 21.4;MCF7: 40.8;RT4: 18.8;SK-BR-3: 18.5;T-47d: 26.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" 0.2 0.3 0.5 3.1 0.6 0.6 6.2 1.8 0.9 4.0 6.5 23.6 31.1 1.8 7.3 4.2 4.2 4.8 0.3 1.1 0.5 12.9 5.3 2.4 0.5 0.4 0.5 0.5 17.1 12.5 1.0 5.7 0.5 6.0 18.7 2.1 11.6 2.5 0.8 3.3 33.1 0.6 0.1 0.4 2.8 0.9 0.5 0.9 3.9 0.0 1.7 3.8 2.5 0.9 21.7 0.7 0.5 0.9 0.0 0.1 30.9 0.0 0.0 0.0 0.0 23.6 22.5 0.2 2.3 0.0 0.1 21.4 1.9 10.3 0.1 0.0 12.1 0.0 0.4 6.2 0.0 0.1 0.2 0.9 12.5 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.0 40.8 0.2 0.3 3.5 13.4 0.2 0.0 0.1 8.8 0.3 18.8 3.7 0.2 0.4 18.5 0.0 2.4 26.3 0.3 0.0 0.0 0.4 0.4 0.2 0.2 0.3 0.1 0.2 0.2 0.2 1.8 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.2 0.1 0.5 0.6 1.8 0.9 1.1 0.5 0.4 0.5 0.5 0.1 0.5 0.9 0.3 9.6 8.4 0.3 0.8 7.9 28.7 9.6 22.8 7.0 25.4 10.7 0.6 40.0 17.9 9.2 0.0 36.5 1.5 150.1 1.9 29.8 4.4 14.2 1.5 1.0 61.5 0.0 0.6 33.7 2.5 1.5 6.1 19.4 0.0 3.8 0.4 9.1 3.1 0.0 0.6 68.2 14.2 1.0 1.0 3.3 0.3 1.2 0.0 0.0 0.8 1.0 0.0 0.0 0.6 26.3 102.9 0.7 0.0 38.4 199.3 27.6 17.4 19.6 0.0 4.1 1.6 9.6 5.0 19.6 3.7 4.8 1.4 0.0 61.3 44.3 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cardiomyocytes: 38.1;Cholangiocytes: 20.0;Endometrial stromal cells: 30.6;Fibroblasts: 16.4;Hepatic stellate cells: 23.2;Hepatocytes: 65.8" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 133.3;BJ hTERT+: 498.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 6.3 3.6 9.4 1.3 9.4 0.0 2.8 12.9 7.0 120.0 4.9 57.5 1.9 88.4 3.3 11.1 17.7 5.1 116.1 10.4 27.0 4.8 183.4 6.0 1.0 19.2 16.5 2.7 0.2 0.3 1.0 9.0 15.3 46.0 5.6 0.0 2.3 52.2 37.5 6.3 7.5 44.4 22.2 0.8 1.6 0.5 14.6 0.2 3.2 18.9 4.3 9.9 61.5 32.0 0.0 0.0 0.3 0.4 15.7 17.3 0.1 133.3 498.3 1.8 0.9 0.0 0.0 0.1 0.0 40.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.2 0.0 0.0 5.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.4 12.9 7.0 10.4 27.0 19.2 16.5 15.3 22.2 14.6 32.0 1.1 0.0 1.8 28.1 0.2 2.9 0.1 0.2 0.0 0.0 0.0 0.0 38.1 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.7 30.6 2.0 0.0 0.0 0.2 0.0 0.3 16.4 0.0 0.7 0.0 0.2 23.2 65.8 0.4 0.0 0.9 0.0 0.0 1.9 3.7 7.5 2.5 0.3 1.8 1.0 0.0 0.0 0.0 10.1 0.2 0.0 0.0 0.7 0.1 0.1 0.0 2.4 0.0 0.0 0.0 5.4 4.5 0.0 0.0 0.2 1.7 0.1 0.5 5.1 0.0 0.1 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;brain: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 177.0;Hofbauer cells: 57.4;NK-cells: 422.2;T-cells: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 76.8" "Group enriched" "Detected in many" 57 "NK-cells: 76.8;T-cells: 46.2" "Cell line enhanced" "Detected in some" "HL-60: 108.3;HMC-1: 30.9;K-562: 48.9;MCF7: 34.4;NB-4: 74.8;SCLC-21H: 30.9;THP-1: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 4.7 1.3 18.3 6.6 21.3 20.5 2.5 2.9 41.9 1.1 1.6 2.1 6.6 0.9 0.1 2.1 4.0 4.4 1.4 25.9 8.7 2.4 3.2 9.9 9.4 10.4 11.0 0.7 1.2 0.7 2.7 1.0 8.8 1.3 1.1 2.2 3.2 0.7 0.8 1.9 6.2 0.8 4.7 16.5 4.0 3.1 14.1 3.8 1.6 0.2 4.0 1.6 1.1 23.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.7 0.0 1.0 10.6 13.8 0.4 0.0 0.0 18.1 12.0 1.5 2.9 0.0 108.3 30.9 0.1 0.0 0.2 0.1 0.0 0.0 1.2 48.9 0.1 0.0 34.4 0.3 74.8 8.4 9.0 0.3 0.0 0.1 0.0 0.0 0.0 30.9 0.1 0.1 0.1 0.1 0.9 0.0 27.4 3.3 0.0 0.6 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 46.2 0.0 31.3 0.0 5.7 29.3 0.8 0.9 2.7 16.4 1.0 76.8 0.2 0.3 0.4 7.6 18.3 21.3 2.9 41.9 25.9 8.7 10.4 11.0 8.8 4.7 14.1 23.6 1.4 0.0 1.1 0.3 11.1 0.4 0.1 0.0 0.0 1.4 4.9 7.2 1.3 0.0 0.0 0.0 12.5 0.3 177.0 0.3 0.0 0.0 2.0 0.2 0.5 1.9 7.1 28.6 17.7 0.0 0.5 0.8 11.7 0.5 44.5 0.1 8.6 1.1 57.4 0.0 8.3 0.3 0.0 6.0 14.6 5.1 0.0 11.5 1.8 4.7 3.0 1.3 422.2 2.0 1.6 0.0 1.1 0.0 17.1 0.1 0.3 0.2 0.7 2.0 0.0 0.5 1.2 0.4 4.5 1.3 1.1 0.3 99.7 0.0 1.1 0.0 MC4R ENSG00000166603 "Melanocortin 4 receptor" P32245 18 60371062-60372775 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 3.5;fallopian tube: 3.0;retina: 3.9" "Cell type enriched" "Detected in some" 7 "Bipolar cells: 7.3" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 70 "fHDF/TERT166: 94.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 10.2" HPA016719 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "HPA016719: AB_1853617" "unprognostic (2.29e-1)" "unprognostic (5.31e-3)" "unprognostic (5.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.59e-1)" 0.0 0.2 2.2 0.0 2.4 0.0 0.2 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.0 0.0 0.0 1.8 3.5 0.0 0.0 0.0 0.0 1.0 1.5 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.1 2.7 0.3 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 94.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.1 1.7 1.8 3.5 1.0 1.5 0.7 0.4 2.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.5" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 81.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 21.3 47.6 13.4 13.5 13.7 6.0 60.0 12.4 15.5 21.3 24.9 30.5 27.2 14.4 38.9 25.4 17.2 15.2 54.9 12.0 13.1 73.3 120.5 13.4 17.8 14.8 13.4 14.2 24.6 32.8 14.1 14.2 14.8 48.2 35.9 12.2 28.2 20.6 34.4 19.8 20.7 11.7 16.3 15.6 25.8 8.6 16.0 14.2 44.6 35.4 21.5 27.0 15.0 18.4 38.5 52.4 21.4 82.5 22.4 23.0 36.9 16.4 29.4 35.7 25.7 91.1 46.9 90.4 62.8 25.9 28.0 30.8 37.8 58.8 44.3 47.6 45.6 48.2 24.7 100.5 39.2 24.4 42.8 29.5 30.1 32.6 25.8 15.8 31.7 24.9 63.2 31.6 24.9 103.0 0.3 42.9 29.0 33.2 27.2 46.3 64.5 130.9 92.5 66.9 32.9 36.7 80.1 111.8 38.8 10.1 92.7 59.6 22.7 14.4 22.1 26.1 49.9 22.4 46.2 54.6 23.7 66.3 36.6 2.0 8.4 1.9 6.5 13.5 8.5 9.7 8.4 7.4 19.4 9.9 8.3 9.1 1.3 14.7 8.1 8.1 12.1 8.3 13.4 13.7 12.4 15.5 12.0 13.1 14.8 13.4 14.8 16.3 16.0 18.4 9.1 16.0 23.6 27.4 26.8 13.3 17.5 20.2 22.2 12.6 54.9 28.3 61.5 20.0 22.3 16.5 6.2 48.5 17.6 26.3 21.5 20.6 4.3 94.0 24.0 15.1 29.5 13.9 22.2 18.2 23.0 13.1 30.1 107.0 12.7 22.7 9.7 93.1 18.0 3.3 21.6 22.8 8.2 12.1 11.2 9.8 13.7 14.0 12.4 11.2 17.9 15.4 20.6 30.2 28.0 15.3 17.0 20.3 27.2 29.6 23.6 59.1 17.7 10.8 6.6 15.2 9.0 4.2 12.0 35.9 13.8 63.6 17.9 30.9 33.9 20.9 MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 134.5" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Bipolar cells: 70.4;Cone photoreceptor cells: 127.2;Endothelial cells: 69.7;Microglial cells: 92.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 35.9;SCLC-21H: 65.3;SH-SY5Y: 29.0;SK-BR-3: 43.9;WM-115: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" 44.1 7.6 39.0 6.3 35.1 0.9 39.5 134.5 76.1 16.5 0.4 17.5 11.3 19.4 5.1 14.1 17.8 13.4 52.8 32.3 27.7 17.5 7.7 19.0 6.8 51.3 40.6 4.8 18.8 10.3 44.4 8.4 57.6 17.0 13.7 20.0 32.7 8.5 16.5 24.8 18.7 7.1 29.1 3.6 18.1 2.0 49.3 7.1 27.6 16.3 6.0 15.0 16.9 47.7 0.0 1.6 14.9 4.8 0.5 0.9 2.1 0.0 0.0 0.0 0.0 3.8 2.2 0.1 3.7 1.5 2.5 0.3 3.8 0.0 0.0 0.0 7.4 4.3 0.2 9.1 0.5 0.2 3.1 1.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.2 14.4 5.6 0.5 2.6 4.0 35.9 0.0 0.2 15.0 7.9 5.9 23.6 65.3 29.0 0.0 43.9 0.1 2.4 26.0 0.1 0.6 0.1 12.5 5.4 0.0 7.5 0.4 2.3 23.9 1.0 60.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.4 39.0 35.1 134.5 76.1 32.3 27.7 51.3 40.6 57.6 29.1 49.3 47.7 138.3 0.0 8.4 4.6 2.6 5.5 3.4 1.5 8.0 70.4 12.9 10.0 44.3 12.8 4.6 9.2 127.2 0.0 1.2 10.8 7.9 5.6 0.4 9.9 1.6 69.7 26.5 0.0 58.5 2.6 0.2 7.1 23.0 18.7 1.3 11.2 13.6 3.4 1.4 38.7 60.9 54.6 8.2 2.2 4.6 1.5 0.6 2.5 8.8 92.8 0.1 5.4 0.0 40.7 75.0 1.7 9.8 1.2 3.0 4.2 4.0 10.4 7.2 23.9 0.0 5.2 11.9 0.7 2.7 4.2 9.1 0.1 2.1 0.5 7.4 4.1 MCIDAS "IDAS, MCI, MCIN" ENSG00000234602 "Multiciliate differentiation and DNA synthesis associated cell cycle protein" D6RGH6 5 55219564-55227315 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation, Transcription, Transcription regulation" Activator "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "parathyroid gland: 2.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Collecting duct cells: 1.8;Endometrial ciliated cells: 1.2;Respiratory ciliated cells: 3.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 4.9;HeLa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049981, HPA058073" Uncertain Supported "Nuclear bodies" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear bodies" "HPA049981: , HPA058073: AB_2683596" "unprognostic (3.11e-2)" "unprognostic (7.50e-4)" "unprognostic (2.48e-1)" "unprognostic (2.89e-2)" "unprognostic (1.76e-1)" "unprognostic (3.57e-2)" "unprognostic (2.41e-3)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" "unprognostic (3.63e-2)" "unprognostic (3.17e-2)" "unprognostic (4.67e-1)" "unprognostic (2.90e-3)" "unprognostic (4.17e-2)" "unprognostic (1.79e-1)" "unprognostic (2.88e-2)" "unprognostic (2.70e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 2.9 0.4 0.0 0.6 0.0 0.0 4.9 0.0 0.0 0.4 0.7 4.0 4.4 0.0 0.4 0.0 1.2 0.7 2.9 0.2 0.0 0.2 4.0 0.0 6.6 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 1.9 1.4 0.0 0.0 1.6 0.0 0.1 0.2 0.7 2.2 0.8 1.5 0.0 1.7 2.6 1.3 0.0 2.1 0.5 2.2 0.0 4.0 0.4 0.0 0.0 3.4 0.2 0.1 3.3 4.2 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.7 0.0 0.9 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.4 1.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703741-95284575 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;brain: 37.1" "Cell type enhanced" "Detected in many" "Adipocytes: 113.3;Excitatory neurons: 510.6;Inhibitory neurons: 412.2;Oligodendrocyte precursor cells: 263.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 37.0;classical monocyte: 28.6;eosinophil: 13.2;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.5;non-classical monocyte: 40.6;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.5;monocytes: 41.4" "Cell line enhanced" "Detected in many" "Karpas-707: 71.4;RPMI-8226: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019018 Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA019018: AB_1853665" "unprognostic (1.20e-2)" "unprognostic (6.70e-4)" "unprognostic (1.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" "unprognostic (1.86e-1)" "unprognostic (6.99e-2)" "unprognostic (5.31e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-6)" "unprognostic (5.38e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (4.43e-2)" 21.3 2.3 12.8 12.5 37.1 45.3 15.9 27.7 19.4 6.0 0.0 7.7 5.1 5.9 2.0 6.4 4.9 17.4 3.8 20.9 10.0 4.4 3.7 12.9 6.1 3.8 0.5 1.7 3.2 1.9 4.0 7.3 5.7 3.5 7.2 1.7 3.7 2.2 3.2 4.3 4.9 11.2 0.5 8.8 5.5 2.1 1.4 7.9 4.6 7.9 4.4 21.3 6.1 13.4 0.3 5.2 3.3 0.1 49.0 19.6 0.2 0.3 25.1 2.3 8.1 0.1 13.3 18.7 19.2 0.0 51.1 0.2 0.4 0.2 2.8 0.0 3.6 11.4 13.3 0.2 6.4 23.6 14.6 7.3 0.0 9.0 32.5 21.2 52.7 7.6 0.3 71.4 18.7 0.6 1.4 17.9 4.1 0.3 20.7 0.9 0.2 73.7 52.7 29.0 10.0 0.5 1.7 0.1 37.1 1.4 0.0 21.8 0.3 9.0 13.9 0.4 4.2 5.0 0.1 0.2 41.8 38.5 9.1 37.0 28.6 13.2 0.1 41.4 0.0 0.6 0.1 0.2 22.3 0.3 0.4 0.0 40.5 0.3 40.6 11.4 0.0 8.5 12.8 37.1 27.7 19.4 20.9 10.0 3.8 0.5 5.7 0.5 1.4 13.4 113.3 3.2 10.8 15.3 3.2 18.1 0.2 6.9 3.4 2.2 1.7 1.1 3.1 0.0 6.6 3.7 0.0 0.3 9.8 0.1 0.0 0.0 27.8 5.5 1.2 97.9 0.0 5.0 510.6 0.2 0.2 18.5 5.6 11.6 63.3 0.1 2.2 0.3 12.2 3.3 412.2 0.0 4.1 42.4 76.5 16.2 0.6 63.5 12.4 67.5 32.9 3.2 2.1 263.4 9.0 1.3 0.0 0.0 2.4 0.8 0.0 0.5 3.5 3.5 0.0 1.8 2.0 1.8 1.4 0.7 13.4 0.3 3.7 0.3 0.0 0.6 MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1349.1;tongue: 1843.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1926.9;Proximal tubular cells: 1428.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434" "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favorable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" 274.6 213.6 235.9 86.7 249.7 79.1 137.9 245.9 353.6 89.6 230.2 167.7 154.7 82.0 161.3 125.3 114.5 87.2 1349.1 253.2 261.5 371.6 266.3 89.8 131.9 248.5 218.3 80.4 69.9 411.8 107.2 92.5 253.3 125.5 190.9 240.7 122.0 142.0 792.5 87.7 133.1 171.5 215.7 71.6 192.6 70.5 259.1 170.4 125.5 1843.8 165.4 131.5 62.8 237.7 268.2 219.5 257.8 173.2 369.6 280.9 282.3 215.1 295.9 300.6 304.1 252.5 215.4 355.2 112.8 264.1 358.8 214.3 303.0 355.0 425.5 207.6 253.1 337.0 173.2 376.8 202.1 384.1 223.9 277.7 241.3 271.5 152.7 236.2 235.3 308.1 183.7 217.3 395.1 157.8 300.6 317.5 158.0 376.3 266.5 235.2 349.7 310.5 460.9 251.0 249.9 153.6 182.5 257.7 384.1 205.6 191.9 341.9 149.6 220.3 211.9 187.1 252.9 264.6 264.8 407.6 266.2 312.2 184.1 271.3 186.3 200.2 202.7 267.8 218.8 258.5 236.6 224.6 241.0 258.5 230.3 221.6 28.1 214.6 253.4 184.3 320.9 321.2 235.9 249.7 245.9 353.6 253.2 261.5 248.5 218.3 253.3 215.7 259.1 237.7 44.4 60.9 54.3 54.9 78.7 81.6 109.4 562.9 50.7 165.4 81.0 86.7 1926.9 95.8 227.2 134.3 70.9 248.7 78.4 128.4 630.0 186.2 12.4 116.1 72.6 61.0 62.8 62.9 120.2 108.1 257.0 134.7 112.7 68.8 80.5 95.0 36.0 153.2 397.0 122.8 130.0 115.9 380.5 85.2 65.8 15.1 100.0 98.4 177.9 43.1 155.0 136.3 73.2 51.3 58.8 91.3 99.8 109.1 82.1 48.8 177.4 1428.3 224.5 164.1 59.2 68.3 167.8 58.0 65.6 82.7 84.0 149.5 84.3 137.4 167.8 102.6 ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210402-83431051 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Excitatory neurons: 117.1;Inhibitory neurons: 70.6;Kupffer cells: 74.4;Muller glia cells: 100.6;Oligodendrocyte precursor cells: 123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "MAIT T-cell: 16.0" "Lineage enriched" "Detected in many" 10 "T-cells: 16.0" "Cell line enhanced" "Detected in many" "CACO-2: 139.4;OE19: 158.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: AB_1078272" "unprognostic (7.21e-2)" "unprognostic (3.99e-2)" "unprognostic (2.24e-1)" "unprognostic (3.12e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (7.98e-3)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.41e-3)" "unprognostic (7.10e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.81e-7)" "unprognostic (4.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-2)" "unprognostic (4.51e-2)" 41.4 44.4 13.4 5.2 15.4 0.4 29.9 14.5 18.1 8.0 8.5 7.7 21.7 4.2 6.5 28.6 4.2 15.5 18.6 13.1 17.4 3.6 9.8 8.8 4.2 15.0 19.1 10.8 3.4 19.9 12.5 2.9 18.3 8.4 11.0 30.0 10.3 17.2 34.7 14.4 10.4 7.8 13.4 7.3 23.8 16.1 16.8 5.6 6.7 30.5 4.5 15.3 12.0 13.5 29.0 59.1 1.4 0.0 48.0 44.4 0.1 18.4 47.0 19.2 37.1 139.4 24.9 0.0 46.8 43.4 38.2 29.8 43.4 16.4 20.9 0.0 24.4 0.0 33.8 0.0 61.4 14.3 50.3 49.0 32.3 38.7 26.3 32.1 30.4 0.0 20.4 0.1 26.4 32.7 0.0 16.2 0.0 158.3 23.0 0.0 48.5 27.9 56.8 13.7 5.8 14.9 31.2 45.7 1.0 25.0 0.0 34.5 32.4 11.9 14.1 3.9 0.1 10.9 13.3 0.1 0.0 0.0 35.9 0.0 1.6 0.0 0.8 0.3 16.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 13.4 15.4 14.5 18.1 13.1 17.4 15.0 19.1 18.3 13.4 16.8 13.5 0.9 19.2 12.1 71.8 0.6 1.9 5.1 12.5 6.8 17.1 2.5 0.9 41.0 7.2 12.7 5.5 2.1 0.6 0.5 12.7 1.9 12.3 5.5 0.7 6.8 2.3 0.0 0.0 117.1 9.5 0.9 8.5 62.7 0.2 0.0 11.2 4.2 12.1 7.1 13.5 70.6 4.1 8.2 74.4 25.6 6.5 25.7 16.7 0.0 23.4 5.5 100.6 0.0 123.6 38.6 15.0 4.5 37.2 0.5 5.2 15.2 3.1 7.2 7.5 0.0 4.5 8.3 7.5 2.3 22.3 3.4 0.8 1.8 33.6 8.9 3.3 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 7.6;Kupffer cells: 15.1;Macrophages: 15.5;monocytes: 26.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Group enriched" "Detected in many" 4 "granulocytes: 8.3;monocytes: 5.7" "Cell line enriched" "Detected in some" 6 "THP-1: 6.6" "Not detected" "Not detected" HPA077497 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA077497: " "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-2)" "unprognostic (2.01e-1)" "unprognostic (2.49e-2)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" "unprognostic (8.89e-2)" "unprognostic (3.27e-1)" "unprognostic (7.58e-7)" "unprognostic (1.08e-1)" "unprognostic (7.16e-4)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" 2.4 0.6 0.1 6.5 0.2 6.1 0.3 0.4 1.0 0.2 0.3 0.4 0.5 0.2 0.2 0.3 0.6 1.0 0.5 0.3 0.1 0.4 0.7 4.0 0.4 0.3 0.2 0.1 0.2 0.0 0.2 0.8 0.5 0.2 0.3 0.2 0.3 0.0 0.7 0.2 0.6 1.0 0.0 8.9 0.4 1.3 0.3 0.4 0.3 0.3 0.3 1.8 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 1.1 0.0 2.4 3.2 0.1 0.0 3.4 0.0 0.1 0.1 0.0 1.7 0.2 0.0 0.1 8.3 0.3 5.7 0.1 0.0 1.2 0.1 0.2 0.4 1.0 0.3 0.1 0.3 0.2 0.5 0.0 0.3 0.4 0.2 0.0 1.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 7.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.4 0.2 1.0 0.0 0.1 0.0 0.0 15.1 2.4 0.3 0.0 15.5 0.0 0.0 26.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.3 0.7 0.0 0.1 0.0 0.6 0.0 0.0 0.1 MEI1 "MGC40042, SPATA38" ENSG00000167077 "Meiotic double-stranded break formation protein 1" Q5TIA1 22 41699503-41799456 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.4;testis: 39.5" "Cell type enhanced" "Detected in many" "B-cells: 32.8;Early spermatids: 61.3;Late spermatids: 50.8;NK-cells: 29.9;Plasma cells: 94.7;Spermatocytes: 38.1;T-cells: 28.4" "Cancer enhanced" "Detected in many" "cervical cancer: 5.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HeLa: 11.6;HMC-1: 8.5;Karpas-707: 26.8;U-266/70: 29.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 7 "olfactory bulb: 1.4" HPA049240 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA049240: AB_2680689" "unprognostic (1.95e-3)" "prognostic favorable (1.59e-6)" "unprognostic (6.13e-3)" "unprognostic (1.86e-2)" "unprognostic (9.70e-2)" "unprognostic (2.97e-3)" "unprognostic (9.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" "unprognostic (5.96e-2)" "unprognostic (9.65e-2)" "unprognostic (2.62e-1)" "unprognostic (2.45e-10)" "unprognostic (2.82e-1)" "unprognostic (3.02e-1)" "unprognostic (1.85e-1)" "unprognostic (7.39e-2)" 1.3 1.0 2.3 6.7 4.0 12.1 3.0 2.1 2.9 1.5 1.7 6.4 2.6 0.7 0.3 1.6 1.8 1.3 1.0 2.1 2.2 2.8 1.4 4.5 6.6 2.5 3.5 0.8 0.6 0.1 0.9 0.8 2.3 1.5 3.0 1.3 7.0 0.5 0.5 1.2 8.5 0.8 2.1 22.4 4.4 39.5 4.9 2.5 2.3 0.1 8.1 2.7 1.3 2.6 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 2.3 0.0 0.3 0.6 0.2 0.5 0.5 0.2 0.2 0.2 0.0 0.0 0.0 6.7 0.0 2.0 11.6 1.3 1.8 1.4 8.5 0.1 0.1 0.0 0.0 0.3 0.5 0.8 0.4 26.8 0.1 0.0 0.0 6.5 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 3.7 1.0 0.5 0.0 0.0 0.1 29.9 5.1 1.2 0.4 2.8 0.1 18.5 7.2 15.7 29.9 5.6 29.1 21.7 30.1 25.8 6.5 15.4 21.7 24.0 1.3 16.9 2.3 2.3 57.2 18.1 2.3 4.0 2.1 2.9 2.1 2.2 2.5 3.5 2.3 2.1 4.9 2.6 0.7 0.0 3.2 0.0 32.8 0.9 0.3 0.3 0.0 0.6 0.3 0.3 0.9 0.0 0.1 0.0 0.0 0.1 19.9 0.0 0.0 0.1 61.3 0.3 1.0 1.4 0.0 0.4 2.1 0.0 0.2 2.0 2.0 0.1 14.0 0.5 3.3 0.5 7.0 0.0 1.1 2.9 0.0 1.2 3.5 50.8 0.6 11.1 17.8 3.7 15.5 0.1 29.9 1.0 1.1 5.3 0.0 1.2 94.7 0.3 0.1 0.4 0.1 1.1 0.0 0.7 1.7 38.1 26.1 0.0 1.0 0.0 28.4 0.1 0.4 0.3 MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.0;breast: 26.1;heart muscle: 24.9" "Group enriched" "Detected in some" 9 "Adipocytes: 63.5;Endothelial cells: 41.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Cell line enriched" "Detected in some" 14 "HeLa: 25.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: AB_10959299, HPA063788: " "unprognostic (1.36e-3)" "unprognostic (2.15e-4)" "unprognostic (1.25e-1)" "unprognostic (2.58e-3)" "unprognostic (2.01e-2)" "unprognostic (5.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-3)" "unprognostic (6.71e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (9.36e-2)" "unprognostic (3.44e-6)" "unprognostic (2.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.82e-1)" "unprognostic (7.47e-3)" 36.0 0.5 0.0 4.7 0.0 0.0 26.1 0.0 0.1 8.0 0.0 4.7 1.6 5.5 1.1 3.7 9.0 5.7 24.9 0.0 0.0 0.2 0.1 1.4 6.6 0.0 0.0 1.0 1.5 1.2 0.5 0.1 0.0 2.6 2.4 0.0 4.9 1.9 8.3 6.6 5.1 10.6 0.0 10.8 3.0 1.1 0.0 3.0 1.9 17.1 5.3 7.7 7.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 1.8 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.1 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.3 2.7 0.0 0.0 1.7 0.5 0.0 0.3 0.0 0.0 17.5 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.5 0.0 0.0 1.0 0.3 4.1 0.0 0.0 1.2 0.0 0.4 0.6 2.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 41.3 0.0 0.0 0.7 0.0 0.3 4.8 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 1.0 0.0 0.1 0.3 1.8 0.1 1.5 0.3 0.0 0.0 MEOX2 "GAX, MOX2" ENSG00000106511 "Mesenchyme homeobox 2" P50222 7 15611212-15686683 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.9;placenta: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 84.7;Endothelial cells: 37.2;Leydig cells: 40.4;Peritubular cells: 25.2;Sertoli cells: 26.3;Smooth muscle cells: 27.0" "Cancer enriched" "Detected in many" 8 "glioma: 15.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AN3-CA: 248.8;U-138 MG: 62.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "medulla oblongata: 3.5;spinal cord: 9.5" HPA053793 Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA053793: AB_2682264" "unprognostic (1.10e-1)" "unprognostic (4.72e-2)" "unprognostic (9.82e-3)" "unprognostic (4.22e-2)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (3.12e-2)" "unprognostic (1.21e-1)" "unprognostic (5.56e-2)" "unprognostic (1.47e-3)" "unprognostic (4.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.65e-5)" "unprognostic (3.67e-3)" "unprognostic (1.13e-1)" "unprognostic (5.86e-2)" "unprognostic (1.46e-4)" 37.9 1.1 0.6 2.9 0.3 0.0 26.2 0.3 0.7 4.3 0.2 5.7 0.4 2.9 2.4 2.4 5.0 6.1 11.8 0.3 0.7 0.5 0.7 12.9 9.1 2.2 0.9 2.4 1.6 1.2 1.2 42.1 1.0 1.9 1.9 0.2 4.4 1.5 9.9 6.9 2.2 4.5 0.7 0.9 2.3 2.3 1.0 3.3 8.6 13.3 5.3 6.1 4.8 0.5 0.0 0.0 0.0 248.8 2.4 8.5 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 32.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 62.9 0.0 25.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.3 0.7 0.3 0.7 2.2 0.9 1.0 0.7 1.0 0.5 84.7 0.0 0.5 0.7 0.3 8.2 0.0 0.0 0.6 0.0 0.5 1.3 2.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 37.2 0.0 0.0 3.8 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 3.7 0.0 0.0 0.0 9.6 0.2 40.4 0.3 3.6 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 25.2 0.0 0.1 0.0 0.0 0.0 0.0 26.3 1.5 27.0 0.1 0.1 0.1 7.0 0.1 0.8 0.7 0.0 0.0 MEST PEG1 ENSG00000106484 "Mesoderm specific transcript" Q5EB52 7 130486171-130506465 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 771.8" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 833.5;Syncytiotrophoblasts: 999.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 24.2" "Group enriched" "Detected in all" 4 "dendritic cells: 9.1;granulocytes: 19.4;T-cells: 24.2" "Cell line enriched" "Detected in many" 6 "AN3-CA: 12338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005623 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "HPA005623: AB_1079364" "unprognostic (6.14e-2)" "unprognostic (5.06e-3)" "unprognostic (9.82e-2)" "unprognostic (1.64e-3)" "unprognostic (3.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.36e-3)" "unprognostic (1.12e-1)" "unprognostic (7.81e-2)" "unprognostic (6.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (6.20e-5)" "unprognostic (7.09e-2)" "unprognostic (1.05e-1)" "unprognostic (2.30e-1)" "unprognostic (1.67e-2)" 117.5 56.2 30.7 16.1 31.3 12.6 63.1 0.0 27.5 6.1 24.1 27.4 28.7 24.4 6.6 6.8 12.0 23.4 7.5 30.2 73.5 17.8 51.8 43.4 5.5 10.2 19.3 18.8 30.0 8.0 33.2 771.8 14.0 12.7 20.9 39.2 21.4 5.5 6.9 4.6 21.6 17.8 2.5 90.2 8.8 26.3 68.4 10.3 11.8 5.2 4.8 11.0 3.9 9.8 77.9 41.7 197.1 12338.6 3.9 1.2 1.1 84.7 38.5 85.1 40.3 237.2 114.4 37.7 27.1 2.6 74.7 11.0 2.9 1.1 33.3 0.4 0.5 66.8 57.0 39.9 322.2 3.2 0.5 5.9 3.1 64.3 0.1 427.5 32.3 0.1 76.5 0.3 164.9 107.6 7.8 85.0 124.1 113.3 20.0 0.8 2168.8 24.5 92.0 72.0 693.2 2.0 71.9 234.0 1.0 195.6 9.2 57.3 33.6 29.2 0.7 276.1 5.6 3.4 8.6 0.7 103.3 1.2 9.7 19.4 2.6 9.1 0.9 2.9 2.2 3.9 2.5 1.8 9.1 3.4 9.4 24.2 1.5 4.3 1.7 0.4 0.1 6.7 30.7 31.3 0.0 27.5 30.2 73.5 10.2 19.3 14.0 2.5 68.4 9.8 7.4 6.4 6.2 12.7 3.3 4.5 47.3 8.6 9.1 13.5 33.3 36.1 0.9 20.0 5.7 16.5 4.2 833.5 2.1 9.3 11.7 20.3 62.7 8.2 12.7 6.0 29.5 35.9 40.8 40.0 187.8 200.3 3.1 9.5 0.0 6.3 44.6 20.4 92.7 1.7 28.1 19.4 6.1 8.8 3.2 37.5 84.8 6.6 1.8 11.2 1.3 45.3 0.0 18.1 1.8 22.8 27.5 13.5 2.3 27.1 24.6 12.3 2.9 22.0 19.7 205.6 12.0 35.7 36.7 10.0 0.6 999.6 2.1 124.8 31.5 23.4 MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 197.8;Fibroblasts: 75.8;Granulosa cells: 93.3;Leydig cells: 53.7;Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 249.4;ASC TERT1: 249.6;HUVEC TERT2: 263.1;SH-SY5Y: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" 36.6 4.2 0.4 13.3 0.6 0.1 22.7 0.5 1.1 81.8 1.6 15.0 5.0 61.4 22.1 6.1 19.0 73.2 13.8 0.5 0.6 9.4 1.6 20.1 4.2 0.7 0.9 35.8 18.8 4.5 13.2 42.4 0.7 22.1 4.8 4.9 16.5 12.1 2.6 27.6 12.1 30.6 0.5 2.7 8.3 11.2 0.7 1.6 9.5 3.0 2.3 22.5 36.7 0.6 0.0 0.2 93.2 0.3 249.4 249.6 6.2 26.3 102.5 39.7 73.7 24.1 1.1 0.0 82.6 89.7 0.1 0.1 7.2 7.7 15.9 0.1 78.0 0.0 37.1 2.1 23.4 0.1 0.1 104.4 18.8 109.4 42.7 113.1 263.1 0.0 0.2 16.2 19.2 12.5 0.1 0.1 108.8 0.5 0.8 1.5 0.0 4.0 0.9 0.3 5.0 212.1 9.0 36.6 9.6 71.1 11.9 13.0 75.6 65.6 128.4 51.7 2.8 0.1 0.3 0.2 53.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.5 1.1 0.5 0.6 0.7 0.9 0.7 0.5 0.7 0.6 5.5 0.0 1.7 0.0 0.1 6.6 7.8 28.7 8.0 0.2 2.1 3.9 0.9 2.8 10.7 3.7 0.0 4.5 0.0 0.1 0.0 1.3 12.9 5.6 28.7 7.1 10.1 0.0 0.0 0.8 197.8 75.8 2.0 8.3 0.0 93.3 1.4 0.0 7.4 0.0 0.0 0.4 12.2 0.0 7.7 7.6 53.7 0.6 17.8 2.8 0.0 27.7 0.0 0.0 0.0 1.9 0.0 63.9 0.5 1.5 0.0 0.0 1.9 0.8 0.0 3.3 14.7 3.2 8.7 0.6 6.3 29.0 0.9 0.5 0.2 1.2 MFAP3 ENSG00000037749 "Microfibril associated protein 3" P55082 5 154038959-154220478 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 24.3;Inhibitory neurons: 24.5;Microglial cells: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015883, HPA049198" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA015883: AB_1853840, HPA049198: AB_2680672" "unprognostic (6.02e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (1.58e-3)" "unprognostic (2.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (6.58e-3)" "unprognostic (1.21e-1)" "unprognostic (3.07e-2)" "unprognostic (1.53e-2)" "unprognostic (7.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (2.05e-1)" "unprognostic (7.16e-3)" "unprognostic (9.35e-3)" 16.0 8.5 5.4 13.2 5.4 12.1 12.5 8.1 7.0 13.2 10.1 10.8 9.5 12.0 9.8 14.7 9.7 11.8 14.1 5.3 6.3 13.5 13.7 11.3 10.6 5.8 6.2 9.4 7.1 24.4 3.1 19.6 6.3 9.4 10.8 12.2 7.2 9.0 10.4 7.6 9.6 16.6 6.5 11.4 9.6 5.7 5.7 11.8 13.4 17.1 13.0 16.1 6.5 6.0 14.9 19.7 36.5 37.7 29.8 24.7 31.5 26.4 28.0 27.0 37.1 27.4 34.1 25.0 30.6 26.3 25.8 33.5 32.5 35.6 41.9 9.5 21.0 15.7 26.5 12.9 29.5 27.7 16.0 29.2 32.4 35.0 29.1 22.6 38.4 19.9 17.5 20.5 21.4 11.0 15.2 9.9 20.0 16.0 9.9 14.6 40.7 20.8 20.8 21.0 32.1 40.3 27.4 35.0 31.1 30.1 34.6 14.8 32.9 34.3 26.4 19.4 26.9 25.7 33.5 21.4 18.7 19.2 27.4 6.7 7.5 11.9 5.0 7.9 6.9 2.4 4.0 3.5 8.1 2.5 5.2 4.1 6.8 6.5 5.6 3.7 3.9 4.3 5.4 5.4 8.1 7.0 5.3 6.3 5.8 6.2 6.3 6.5 5.7 6.0 9.7 0.0 0.5 14.0 3.5 6.0 1.0 6.1 6.2 3.2 1.6 1.5 2.7 0.0 3.9 5.5 6.2 4.3 2.7 1.9 1.9 1.4 7.1 1.4 4.3 7.6 0.0 9.1 24.3 1.1 3.0 3.9 4.1 2.2 4.5 2.1 1.4 1.9 1.9 3.3 24.5 1.2 8.2 0.6 4.4 4.9 1.8 2.7 8.8 17.8 0.7 6.9 1.0 12.1 15.1 1.1 0.3 0.0 9.5 1.3 2.1 1.1 4.6 4.6 0.0 1.5 3.3 3.9 2.0 4.3 5.5 6.0 4.0 1.2 1.0 1.5 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MFHAS1 "LRRC65, MASL1, ROCO4" ENSG00000147324 "Malignant fibrous histiocytoma amplified sequence 1" Q9Y4C4 8 8783354-8893630 "Disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Signal transduction inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 105.4;Glandular and luminal cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MOLT-4: 128.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051213, HPA054471" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA051213: AB_2681391, HPA054471: AB_2682498" "unprognostic (1.33e-1)" "unprognostic (4.46e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-1)" "unprognostic (1.95e-1)" "unprognostic (8.91e-3)" "unprognostic (2.70e-2)" "unprognostic (2.68e-3)" "unprognostic (9.23e-3)" "unprognostic (7.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.81e-1)" "unprognostic (2.01e-3)" "unprognostic (5.93e-2)" "unprognostic (4.91e-1)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" 5.8 2.0 7.3 7.9 6.9 11.9 3.6 7.5 8.7 6.3 4.1 12.8 6.1 5.1 3.3 5.3 6.6 5.5 6.6 8.3 6.4 13.5 6.0 9.9 10.4 6.1 7.4 3.4 4.6 5.7 2.0 8.8 6.5 5.3 11.4 5.4 3.4 4.4 2.4 6.1 7.0 8.2 6.5 11.1 6.3 6.0 9.0 9.0 5.4 2.7 8.6 9.2 3.5 6.2 19.5 14.4 8.6 6.6 8.0 10.1 28.3 7.9 17.0 5.6 7.6 23.3 3.7 28.5 9.5 7.6 16.2 6.5 9.1 7.3 4.9 37.0 8.1 2.1 5.3 15.1 9.5 8.2 2.9 5.5 15.0 7.6 7.5 6.0 12.5 34.8 13.4 0.0 4.7 7.0 128.0 7.2 16.8 25.8 6.1 17.4 13.1 4.4 39.3 20.0 13.6 11.0 4.6 7.2 12.7 14.6 4.9 11.1 5.3 6.8 10.1 27.3 15.4 1.5 6.9 21.7 12.6 10.8 4.2 0.0 0.1 0.0 0.9 0.0 0.7 0.4 1.3 0.8 0.2 0.3 0.6 0.5 0.0 0.1 0.0 0.0 1.2 0.3 7.3 6.9 7.5 8.7 8.3 6.4 6.1 7.4 6.5 6.5 9.0 6.2 10.7 54.5 43.9 105.4 6.5 37.5 24.5 6.0 2.8 19.0 6.2 3.2 17.2 20.0 16.5 31.3 4.2 3.7 6.5 30.9 13.7 12.0 2.5 50.8 20.3 19.2 18.8 71.4 46.9 15.4 3.2 17.8 8.2 119.2 22.2 5.4 25.4 17.8 31.8 3.3 56.8 29.3 10.2 27.5 21.0 3.4 11.5 13.0 10.6 61.8 8.0 24.3 14.4 38.2 6.2 28.5 20.7 8.2 2.1 47.5 6.7 16.5 5.4 8.1 0.0 4.5 24.1 1.9 21.7 2.4 50.0 2.3 24.0 1.7 36.3 16.9 MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 228.0;retina: 116.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 151.3;Granulosa cells: 93.5;Horizontal cells: 208.6;Muller glia cells: 508.9;Theca cells: 474.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 20.4;fHDF/TERT166: 30.7;HHSteC: 23.6;HUVEC TERT2: 61.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA015994: AB_2630370, HPA070835: " "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.42e-2)" "unprognostic (1.02e-3)" "unprognostic (2.90e-2)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" 9.4 228.0 3.2 0.3 3.2 0.1 1.8 7.8 4.6 2.0 3.1 1.0 0.2 5.0 1.8 0.4 2.2 0.9 3.0 3.1 4.0 1.8 0.2 0.7 0.9 3.7 4.0 23.9 0.3 0.2 11.8 0.3 3.7 2.6 0.3 116.9 0.4 4.0 0.8 0.4 0.3 3.8 3.2 0.8 0.4 8.6 3.6 0.3 0.8 0.3 0.6 1.1 2.5 3.6 0.0 1.1 0.6 0.5 1.5 0.7 0.1 20.4 0.1 3.0 0.1 0.1 0.2 0.1 0.2 30.7 8.7 0.5 4.4 0.1 1.7 0.0 2.0 0.0 0.1 0.2 23.6 0.2 0.2 7.2 0.7 3.3 0.2 7.1 61.7 0.2 0.4 0.4 5.1 0.1 0.8 0.5 1.1 0.4 0.1 0.1 0.0 0.0 0.7 0.3 0.6 1.2 0.0 0.0 0.2 0.3 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.8 0.7 0.5 8.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.2 3.2 7.8 4.6 3.1 4.0 3.7 4.0 3.7 3.2 3.6 3.6 0.6 0.0 0.0 0.0 0.2 1.7 0.7 0.4 1.2 151.3 0.7 10.8 3.5 0.0 0.1 0.0 8.4 0.2 0.3 0.1 1.9 0.0 0.3 0.8 1.2 1.1 0.0 0.0 1.3 0.0 0.2 10.7 0.0 0.3 0.0 93.5 0.4 0.4 0.5 208.6 2.5 0.0 0.0 0.0 0.3 0.6 17.1 0.6 0.0 0.0 0.0 508.9 2.1 5.0 0.7 0.1 0.0 24.8 0.3 0.3 0.1 9.2 0.0 32.6 0.0 1.9 3.4 0.8 0.4 0.7 0.9 0.3 0.6 474.8 0.1 0.3 MGAT3 GNT-III ENSG00000128268 "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase" Q09327 22 39457012-39492194 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.0;intestine: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Bipolar cells: 30.7;Excitatory neurons: 25.1;Inhibitory neurons: 27.4;Oligodendrocytes: 45.7;Proximal enterocytes: 37.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4;eosinophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 65.1;HMC-1: 56.0;OE19: 58.8;U-266/70: 73.6;U-266/84: 32.6;U-698: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved "Intracellular and membrane" NA NA 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA017598: AB_1853853" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (5.71e-3)" "unprognostic (8.92e-2)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (6.77e-2)" "unprognostic (8.12e-3)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.04e-8)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (5.89e-2)" "unprognostic (4.92e-2)" 7.8 1.1 26.8 4.0 20.9 10.8 6.4 7.6 47.0 6.2 0.0 5.2 21.5 3.8 0.8 1.1 3.4 3.8 4.8 30.3 10.0 3.0 0.2 14.9 7.6 28.1 15.6 1.2 3.1 0.4 1.8 10.5 21.8 1.2 4.6 6.7 1.8 1.0 1.5 2.3 28.4 2.8 4.8 4.8 7.4 5.4 23.9 1.8 1.5 1.8 9.0 1.6 1.5 27.3 0.3 0.4 10.4 1.0 0.0 0.0 65.1 0.5 0.7 0.5 0.0 14.9 3.7 23.4 8.1 0.0 0.2 1.3 5.4 0.0 0.1 0.0 0.5 18.9 0.0 0.2 0.2 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 15.8 2.9 0.0 0.2 0.6 1.4 3.1 58.8 0.0 1.2 0.0 3.9 0.4 0.6 6.0 4.4 0.0 0.0 0.0 18.5 0.8 1.0 0.0 0.1 8.1 0.1 0.1 73.6 32.6 32.6 0.2 0.1 1.7 1.4 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.8 20.9 7.6 47.0 30.3 10.0 28.1 15.6 21.8 4.8 23.9 27.3 2.0 44.8 3.0 6.5 2.2 0.4 0.1 1.8 0.0 30.7 0.6 1.1 1.9 1.5 3.7 0.0 6.2 5.5 0.0 4.1 0.0 0.0 19.1 0.9 11.0 2.5 7.8 13.7 25.1 0.2 12.0 2.3 10.2 2.0 2.5 0.0 0.0 0.0 1.5 13.5 27.4 3.8 2.0 0.0 2.3 16.6 4.4 0.9 0.0 0.0 0.1 1.5 0.0 21.6 45.7 1.8 6.1 3.8 1.7 0.3 37.4 1.8 5.2 2.3 6.6 0.3 4.3 0.7 1.2 0.2 0.6 3.7 0.5 0.6 4.5 1.5 MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 565.4;Distal enterocytes: 398.7;Pancreatic endocrine cells: 535.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Cell line enhanced" "Detected in many" "BJ: 209.1;BJ hTERT+: 238.6;LHCN-M2: 191.3;RPTEC TERT1: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 174.8 16.1 100.8 22.9 91.0 18.9 92.0 87.2 123.4 26.8 48.0 81.9 36.9 17.7 9.9 139.9 34.3 44.8 101.9 96.9 75.9 71.0 106.9 72.0 13.5 72.5 86.6 6.1 7.8 3.6 12.5 41.6 70.9 25.8 60.4 6.2 102.1 27.5 66.0 38.1 50.3 27.8 63.0 44.9 38.2 6.2 107.2 10.0 18.9 64.9 21.3 42.5 39.4 88.6 52.4 46.2 0.1 0.5 76.8 90.0 6.2 209.1 238.6 45.3 72.2 1.2 21.0 14.0 56.9 71.3 13.7 2.1 0.4 27.9 25.2 23.5 0.9 1.6 31.4 0.4 27.7 0.3 1.7 34.2 16.1 85.0 92.4 25.6 97.5 1.0 0.3 3.0 191.3 5.6 0.5 0.9 0.5 33.6 71.5 0.2 24.6 109.4 170.4 5.9 26.5 2.1 36.3 70.4 12.6 2.0 3.5 2.1 125.9 49.5 14.8 121.0 29.1 0.5 0.4 43.4 102.4 3.4 156.6 20.6 8.3 36.0 0.5 84.7 2.8 4.9 0.5 1.1 9.2 0.5 0.2 0.2 1.5 2.0 57.2 89.8 0.0 17.1 100.8 91.0 87.2 123.4 96.9 75.9 72.5 86.6 70.9 63.0 107.2 88.6 565.4 195.5 108.6 83.2 8.5 22.8 11.9 14.1 5.7 22.8 25.2 19.9 53.7 118.7 32.2 42.3 0.0 84.6 16.1 398.7 168.3 99.4 4.1 100.0 36.4 207.7 88.6 30.7 39.0 160.7 154.6 71.5 47.9 132.1 8.8 0.1 17.2 148.7 123.9 0.0 48.9 239.1 63.1 32.8 86.3 5.8 32.6 77.8 21.4 52.5 235.2 54.5 2.1 43.2 5.8 535.2 201.0 69.6 36.2 18.5 134.2 102.0 48.0 7.8 85.5 22.3 141.4 0.7 1.7 64.7 22.3 72.7 9.3 1.1 74.0 6.0 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1205.9;Club cells: 1308.7;Hepatocytes: 4345.6;Proximal tubular cells: 1265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Cell line enhanced" "Detected in many" "ASC diff: 5391.4;ASC TERT1: 2078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" 1096.9 1137.3 139.2 76.1 143.9 79.3 574.8 131.4 200.7 69.7 111.9 315.5 128.9 32.7 43.9 195.3 78.4 200.8 135.1 133.9 165.4 392.9 3104.7 177.2 3.5 156.5 155.7 11.4 131.3 0.8 52.6 14.2 166.6 161.2 212.8 7.0 155.3 55.8 25.5 88.8 119.5 44.7 146.4 7.3 131.4 20.2 147.5 14.0 272.3 43.3 7.7 267.9 114.7 132.9 1.4 495.2 115.6 139.4 5391.4 2078.4 1.5 408.5 418.5 220.6 339.1 186.0 838.6 0.4 48.5 535.8 694.2 2.4 317.0 663.5 202.9 1.1 41.4 175.7 256.6 664.8 1252.0 350.4 1.2 1375.9 714.7 671.2 710.5 540.4 393.1 0.1 126.7 0.6 486.3 101.2 0.3 137.0 987.6 0.7 391.2 0.4 69.3 229.3 503.3 982.1 21.8 17.1 645.8 411.8 17.5 630.1 442.5 190.8 248.0 226.1 30.5 447.3 541.1 0.6 1.7 1.5 748.1 538.5 7.1 11.3 170.2 1.8 0.1 26.3 0.5 1.0 0.2 0.1 123.5 0.0 0.1 0.1 5.9 0.2 5.9 34.1 1.1 55.9 139.2 143.9 131.4 200.7 133.9 165.4 156.5 155.7 166.6 146.4 147.5 132.9 39.6 266.0 651.3 130.2 14.0 25.6 130.2 1205.9 91.0 0.0 383.8 262.6 5.1 574.7 1308.7 71.7 0.0 2.9 9.8 288.1 181.9 26.9 25.4 299.9 198.2 19.6 45.6 92.8 4.4 434.1 218.1 404.5 153.9 947.9 34.1 26.3 67.5 4345.6 160.2 0.0 0.5 280.5 740.6 176.4 52.0 17.9 33.2 75.7 39.2 6.5 224.4 1.0 5.2 1.0 0.8 322.7 175.0 113.2 6.0 467.2 209.5 1265.6 526.1 1.3 0.0 11.3 124.3 0.7 2.3 510.3 17.6 7.9 22.1 152.4 534.1 883.3 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2092.0;Syncytiotrophoblasts: 2371.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 793.9;OE19: 781.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA053311: AB_2682108, HPA077929: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 260.2 163.3 218.0 57.7 224.9 126.2 196.5 245.4 273.1 96.6 214.1 219.6 358.6 91.9 520.6 97.6 112.3 114.4 770.2 232.6 258.0 254.3 166.8 117.5 48.9 239.5 228.8 118.0 90.1 139.1 86.1 173.2 248.3 113.4 217.8 89.9 164.0 114.8 568.0 87.8 301.6 118.8 227.4 54.4 163.0 64.2 230.3 51.9 142.9 578.7 47.7 107.2 90.0 240.5 178.2 128.0 150.0 106.1 533.4 312.1 653.1 158.1 244.2 119.1 205.2 126.8 219.1 10.9 117.1 198.6 117.8 204.7 36.2 155.2 118.5 793.9 94.5 27.1 84.7 60.4 144.9 45.0 58.9 284.2 107.5 178.0 62.3 239.4 202.0 54.2 72.3 65.6 233.6 37.0 48.9 97.4 292.3 781.6 165.8 44.8 63.0 22.2 599.8 159.4 104.1 134.2 148.7 181.1 313.2 308.4 139.1 215.9 174.7 135.8 82.6 92.9 110.8 49.7 37.0 5.8 239.8 109.7 92.3 44.8 172.9 81.2 107.2 150.2 107.9 79.3 130.5 117.3 138.0 78.2 81.4 89.1 32.3 62.3 195.0 58.2 125.5 185.0 218.0 224.9 245.4 273.1 232.6 258.0 239.5 228.8 248.3 227.4 230.3 240.5 915.1 102.5 164.8 48.3 87.6 228.3 251.8 603.8 111.0 144.6 177.0 267.6 670.1 301.7 292.6 557.3 266.9 2092.0 96.5 500.3 1001.8 380.2 18.2 325.6 132.6 268.0 152.8 785.4 75.8 425.9 1327.2 300.3 193.7 257.7 91.8 519.5 257.7 295.0 837.4 131.2 86.4 302.9 374.3 130.0 243.1 46.1 388.0 234.9 519.4 43.1 296.6 257.9 87.6 45.8 90.6 401.8 613.9 399.8 92.9 173.9 1004.1 1227.6 459.9 162.5 506.2 197.5 652.1 23.1 40.4 157.1 232.6 2371.4 123.1 288.6 440.7 237.6 MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 44.1;Ductal cells: 42.9;Endometrial ciliated cells: 78.7;Exocrine glandular cells: 42.7;Glandular and luminal cells: 93.5;Pancreatic endocrine cells: 41.3;Proximal tubular cells: 61.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 125.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" 12.1 26.6 5.6 16.8 6.9 23.6 22.1 5.8 7.9 29.7 58.0 30.8 80.4 15.7 40.2 26.9 22.2 30.3 16.6 9.4 6.5 78.4 138.9 15.5 16.2 5.6 4.7 9.6 43.6 40.5 15.5 11.2 6.4 21.1 34.6 12.8 52.5 19.2 54.5 9.9 78.4 12.3 4.1 14.5 45.3 21.0 5.1 14.3 46.7 20.7 19.8 16.2 17.2 7.1 23.0 25.1 10.4 18.5 20.6 23.2 14.5 13.3 13.9 9.3 9.6 19.7 125.4 27.5 40.1 15.0 18.9 34.1 12.7 15.0 11.0 21.4 10.6 17.2 11.5 106.1 48.2 23.2 30.7 14.4 83.7 9.2 69.2 59.0 15.3 31.8 16.6 68.3 14.0 22.1 14.9 18.9 12.0 87.2 20.8 15.2 18.3 34.9 42.7 24.7 8.7 5.1 31.0 32.5 20.4 13.1 31.2 24.8 24.3 14.1 9.2 10.4 8.8 38.7 35.7 27.2 7.9 14.5 12.0 40.9 16.3 25.9 15.4 18.0 14.0 11.7 11.6 14.4 17.8 13.1 14.2 13.2 34.5 14.6 21.0 12.3 11.8 11.8 5.6 6.9 5.8 7.9 9.4 6.5 5.6 4.7 6.4 4.1 5.1 7.1 26.7 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 33.1 19.9 0.0 5.7 0.0 44.1 0.0 5.6 35.9 0.8 7.9 42.9 0.5 78.7 30.7 7.1 0.0 0.0 0.1 42.7 5.0 4.6 0.0 93.5 0.0 10.3 0.0 3.8 7.6 0.0 0.1 1.8 0.0 0.0 0.0 0.6 0.0 12.7 0.0 0.0 23.8 0.0 1.0 0.0 0.0 41.3 0.0 0.0 8.1 0.0 6.6 61.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.0 13.6 20.0 0.2 0.0 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 129.3;Basal squamous epithelial cells: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 156.1;AF22: 132.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 5.9 2.5 6.9 5.0 7.7 1.7 5.3 17.2 5.0 7.0 6.5 17.3 5.7 8.9 4.9 7.0 6.4 6.8 9.3 7.0 4.9 7.3 4.2 6.5 2.2 3.6 10.4 4.4 3.5 2.8 4.2 6.2 4.9 10.4 10.6 12.3 4.9 12.9 0.7 2.9 5.8 12.3 2.1 1.0 3.8 3.6 8.2 2.3 4.2 2.2 3.1 11.7 6.2 4.4 33.2 156.1 132.5 16.7 8.1 9.2 14.6 16.2 17.8 19.7 20.7 31.0 9.7 10.6 6.5 21.9 58.4 22.5 11.0 15.1 23.0 1.3 11.0 2.7 24.3 1.1 2.8 0.3 1.2 12.1 7.0 16.1 15.8 20.4 23.1 5.1 2.1 3.2 9.6 8.0 5.3 0.5 32.7 5.1 10.0 3.9 28.9 0.4 18.7 36.2 7.1 3.5 7.4 23.5 10.1 42.7 19.2 0.2 13.7 7.2 1.0 34.1 17.0 2.8 1.2 0.4 13.5 0.3 31.3 0.5 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.7 0.0 0.1 0.4 0.0 0.1 6.9 7.7 17.2 5.0 7.0 4.9 3.6 10.4 4.9 2.1 8.2 4.4 16.5 35.3 20.7 129.3 0.7 21.4 31.5 24.7 82.6 10.7 8.5 13.2 4.8 8.6 19.6 23.9 18.8 9.1 1.3 22.6 1.9 13.4 2.2 39.8 8.9 25.4 12.1 2.7 15.5 8.7 26.9 16.2 10.7 38.5 1.3 13.4 69.9 4.0 1.5 69.0 44.3 9.0 2.0 2.5 5.8 7.9 30.1 1.2 3.6 23.4 0.0 37.0 0.0 66.4 59.2 7.3 17.2 41.3 0.2 8.2 11.3 1.5 19.3 2.9 6.6 3.7 3.3 0.3 2.4 36.1 10.1 20.0 0.8 9.7 20.0 49.2 MIEF1 "FLJ20232, L0R8F8, MiD51, SMCR7L" ENSG00000100335 "Mitochondrial elongation factor 1" Q9NQG6 22 39499432-39518132 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 266.3;Late spermatids: 377.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061059 Approved "Intermediate filaments,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments, Mitochondria" "HPA061059: " "unprognostic (5.35e-2)" "unprognostic (2.66e-2)" "unprognostic (2.86e-3)" "unprognostic (1.11e-2)" "unprognostic (3.74e-2)" "unprognostic (1.49e-1)" "unprognostic (1.95e-3)" "unprognostic (1.85e-2)" "unprognostic (5.72e-2)" "unprognostic (1.76e-1)" "unprognostic (3.24e-1)" "unprognostic (6.65e-2)" "prognostic favorable (3.96e-5)" "unprognostic (1.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.30e-1)" 9.6 8.1 10.9 7.9 10.4 12.8 8.4 10.9 10.4 6.3 8.5 9.5 12.0 7.6 6.8 9.3 7.1 5.5 8.8 10.2 9.9 13.1 16.3 7.4 11.2 10.4 11.5 7.7 9.5 10.9 5.1 8.6 11.1 6.9 9.3 8.3 9.8 8.1 8.4 7.9 10.4 6.8 10.8 9.2 8.2 17.1 11.4 9.5 8.4 9.3 11.7 7.3 6.3 10.3 16.0 15.9 16.5 26.6 15.5 17.0 19.5 15.0 17.4 16.7 15.0 25.9 8.1 44.4 12.2 15.7 10.9 20.0 37.6 20.4 20.1 18.8 36.3 18.1 22.4 26.2 30.1 63.7 23.1 22.3 24.3 14.7 30.7 16.1 17.9 14.5 32.5 23.4 16.7 11.0 20.5 17.8 15.4 32.5 17.2 27.7 23.4 44.6 19.0 18.8 15.3 12.7 16.6 27.6 42.8 17.3 12.3 22.7 17.8 15.7 22.1 14.0 18.6 42.2 47.5 43.9 18.1 28.0 24.7 0.4 5.6 4.7 5.2 6.2 6.4 4.8 5.0 5.1 6.0 4.7 5.4 5.1 0.4 6.8 6.2 3.3 4.7 6.3 10.9 10.4 10.9 10.4 10.2 9.9 10.4 11.5 11.1 10.8 11.4 10.3 10.9 12.8 18.7 7.5 13.6 19.5 16.0 11.4 10.8 19.0 13.6 12.1 19.3 20.0 8.6 16.5 25.0 19.6 17.0 22.0 25.4 13.1 266.3 5.2 14.3 13.1 9.7 14.7 7.4 13.8 19.8 10.4 8.2 8.9 9.5 14.2 16.8 49.8 15.8 6.7 8.3 11.5 24.4 20.7 20.5 377.2 15.5 12.2 16.0 9.4 19.0 18.7 7.2 2.0 8.9 17.6 7.6 13.9 29.1 23.4 21.9 27.8 8.9 15.2 0.0 14.1 10.2 20.4 28.0 16.2 23.0 13.0 10.8 14.7 20.7 19.1 MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 793.4;Intestinal goblet cells: 230.9;Paneth cells: 646.7;Proximal enterocytes: 1115.2;Undifferentiated cells: 220.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 121.4;HaCaT: 90.2;hTCEpi: 82.6;MCF7: 63.2;OE19: 76.9;SK-BR-3: 134.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" 1.3 0.0 0.3 12.1 0.3 0.0 0.9 0.5 0.4 4.4 0.1 95.5 171.0 0.7 0.0 0.3 9.8 11.3 0.0 0.4 0.3 8.8 0.1 9.3 0.1 0.5 0.5 0.3 1.7 0.0 8.1 1.2 0.5 5.6 48.4 0.0 1.0 0.5 0.0 0.6 196.6 3.3 0.2 0.0 22.9 0.5 0.3 0.3 0.1 0.0 0.0 9.0 0.6 0.2 30.4 121.4 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 42.1 44.2 10.8 11.5 0.0 0.1 90.2 0.0 37.7 0.0 0.0 0.1 0.0 47.0 13.3 0.0 0.0 1.9 0.0 82.6 0.3 4.5 0.0 0.0 0.0 0.0 0.4 0.2 63.2 0.1 0.7 0.1 76.9 24.6 0.2 0.4 1.0 30.1 33.7 1.4 0.4 42.9 134.3 0.1 0.1 29.3 0.0 0.0 0.0 14.8 1.8 0.2 0.6 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.4 0.3 0.5 0.5 0.5 0.2 0.3 0.2 0.1 38.5 8.0 0.3 2.9 0.1 4.5 22.5 0.0 0.0 4.7 2.3 0.5 10.0 39.7 11.0 0.0 0.6 0.0 793.4 1.9 39.9 0.6 40.5 1.5 0.8 58.0 0.0 0.2 46.0 6.0 2.4 56.6 14.3 8.9 0.0 0.0 0.0 0.1 0.0 0.3 230.9 28.5 0.0 0.0 0.9 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.2 157.7 646.7 0.0 0.1 41.6 1115.2 27.5 41.3 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.3 2.1 1.6 0.0 220.7 62.1 MITF "bHLHe32, MI, WS2, WS2A" ENSG00000187098 "Melanocyte inducing transcription factor" O75030 3 69739464-69968336 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Albinism, Cancer-related genes, Deafness, Disease variant, Microphthalmia, Osteopetrosis, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 133.5;Melanocytes: 585.2;Oligodendrocyte precursor cells: 166.9;Oligodendrocytes: 240.3" "Cancer enriched" "Detected in all" 4 "melanoma: 39.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 5.2;classical monocyte: 9.4;intermediate monocyte: 3.3;myeloid DC: 6.1;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 6 "dendritic cells: 6.1;granulocytes: 5.2;monocytes: 9.4" "Cell line enhanced" "Detected in many" "HMC-1: 89.1;SK-MEL-30: 254.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002578, HPA003259" Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB002578: AB_564111, HPA003259: AB_1079381" "unprognostic (3.29e-1)" "unprognostic (4.26e-2)" "unprognostic (2.98e-2)" "unprognostic (6.04e-2)" "unprognostic (1.03e-1)" "unprognostic (3.25e-1)" "unprognostic (1.04e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-1)" "unprognostic (5.31e-3)" "unprognostic (3.87e-3)" "unprognostic (1.94e-1)" "prognostic favorable (8.35e-10)" "unprognostic (6.37e-2)" "unprognostic (1.08e-1)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" 13.8 4.4 5.1 3.8 9.2 1.7 10.0 9.4 6.3 51.3 21.2 18.8 2.8 46.2 4.5 8.9 10.3 16.8 31.1 5.2 9.3 20.0 2.2 9.7 3.4 12.5 9.5 18.7 4.2 16.8 3.8 3.3 10.4 8.4 4.5 1.2 5.1 14.1 50.6 11.0 5.8 46.0 7.0 2.0 9.4 2.3 10.3 2.2 7.6 43.3 1.5 10.6 16.6 13.8 17.2 12.2 1.3 5.1 18.8 0.3 2.0 16.9 9.9 7.8 4.8 6.1 0.8 0.0 4.0 0.3 21.6 8.6 3.7 9.4 8.6 0.0 2.5 37.1 24.5 0.3 4.5 0.8 89.1 15.3 3.9 2.2 8.6 29.1 2.4 0.0 12.3 5.2 5.4 1.2 0.7 1.0 0.7 0.7 8.3 0.1 1.9 7.7 45.2 9.0 0.4 1.9 8.8 3.1 254.1 2.0 0.7 2.3 0.1 3.8 13.3 5.1 3.5 0.6 1.0 0.1 7.7 2.6 9.2 5.2 9.4 0.0 0.0 3.3 0.0 0.0 0.0 0.1 6.1 0.0 0.0 0.0 0.7 1.1 5.9 0.5 0.0 3.1 5.1 9.2 9.4 6.3 5.2 9.3 12.5 9.5 10.4 7.0 10.3 13.8 4.6 28.9 6.8 34.3 0.2 42.8 3.6 16.7 7.4 1.6 1.8 1.8 109.5 11.5 18.2 14.7 0.0 1.3 0.6 0.4 50.9 14.7 1.6 24.5 94.3 7.4 1.2 8.6 14.7 8.8 1.0 38.3 9.7 71.2 106.8 10.9 4.6 2.1 45.8 6.7 133.5 0.3 12.2 30.8 30.9 3.4 44.4 24.3 585.2 50.6 10.6 1.4 0.0 166.9 240.3 7.7 0.0 50.4 0.4 5.2 0.2 24.3 12.5 0.2 13.1 17.8 22.6 4.0 6.3 7.2 18.9 1.1 3.8 5.5 0.6 7.1 MIXL1 "MILD1, MIXL" ENSG00000185155 "Mix paired-like homeobox" Q9H2W2 1 226223618-226227060 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 5 "Plasma cells: 18.5" "Cancer enriched" "Detected in some" 9 "testis cancer: 6.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 9.0;SuSa: 1.9;U-698: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA005662 Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA005662: AB_2667382" "unprognostic (4.09e-2)" "unprognostic (2.84e-2)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.03e-2)" "unprognostic (3.18e-2)" "unprognostic (5.66e-2)" "unprognostic (5.05e-2)" "unprognostic (7.40e-3)" "unprognostic (2.78e-2)" "unprognostic (2.70e-1)" "unprognostic (2.71e-13)" "unprognostic (1.54e-1)" "unprognostic (1.29e-2)" "unprognostic (1.67e-1)" "unprognostic (8.47e-2)" 0.1 0.1 0.3 1.0 0.2 0.2 0.2 1.2 0.3 0.1 0.2 0.7 1.3 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.2 2.4 0.3 0.2 0.2 0.1 0.6 0.0 0.2 0.3 0.1 0.6 0.1 0.2 0.2 0.0 0.2 0.7 0.1 0.1 1.0 0.8 0.4 0.2 0.2 0.1 0.0 3.4 0.6 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.1 0.2 9.0 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.4 0.0 0.0 0.0 49.7 6.5 13.0 6.4 10.0 12.6 11.3 7.3 7.3 7.2 10.4 9.6 9.7 18.2 19.6 19.5 11.0 10.3 6.2 0.3 0.2 1.2 0.3 0.2 0.2 0.3 0.2 0.3 0.1 0.2 0.4 0.6 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.3 0.2 0.1 1.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.5 0.1 0.1 0.1 0.0 0.5 0.0 0.3 0.1 0.1 1.5 0.0 0.0 0.3 0.1 0.1 0.0 0.1 MLEC KIAA0152 ENSG00000110917 Malectin Q14165 12 120687149-120701859 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Undifferentiated cells: 397.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 880000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.60e-6)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (5.41e-2)" "unprognostic (3.94e-1)" "unprognostic (3.39e-1)" "unprognostic (9.77e-2)" "unprognostic (5.90e-2)" "unprognostic (1.76e-1)" "unprognostic (1.15e-2)" "prognostic favorable (8.77e-4)" "unprognostic (1.98e-1)" "unprognostic (7.88e-2)" "unprognostic (1.05e-1)" 51.7 93.1 35.4 51.8 36.7 34.6 44.3 33.0 34.5 52.8 40.3 127.0 78.3 37.2 138.1 24.5 48.5 48.5 65.9 34.7 40.0 73.5 78.2 34.9 30.3 42.3 39.4 49.2 62.7 101.2 36.7 45.7 37.8 62.4 117.3 25.3 50.7 64.9 79.8 27.8 86.0 50.0 40.0 30.1 45.3 69.1 42.9 33.3 101.0 82.9 37.3 34.1 17.4 37.6 122.7 177.9 113.6 151.8 196.3 107.4 127.9 144.5 126.3 108.9 80.1 127.5 75.1 100.3 129.0 142.2 85.4 101.9 140.4 87.4 138.7 86.5 76.9 142.4 79.4 100.6 72.1 199.3 123.1 82.2 82.7 116.0 91.4 174.1 97.2 93.9 85.9 112.2 116.3 127.8 106.4 122.2 158.1 156.6 91.7 115.7 82.0 109.1 132.2 204.0 58.2 69.2 166.5 85.9 86.0 143.0 127.0 144.6 79.2 115.8 108.5 112.8 100.3 83.3 165.0 76.8 147.6 147.9 120.1 0.5 6.0 8.0 3.8 7.5 4.1 4.7 2.3 3.4 5.0 6.9 4.0 3.4 1.6 3.9 6.5 18.6 2.4 2.2 35.4 36.7 33.0 34.5 34.7 40.0 42.3 39.4 37.8 40.0 42.9 37.6 151.4 25.6 62.2 23.2 65.7 72.8 70.6 32.0 55.2 40.9 99.7 76.3 145.3 97.2 40.0 86.5 45.9 88.4 105.7 155.3 37.2 134.2 243.3 78.3 127.6 94.1 80.3 68.5 21.4 183.7 176.9 90.5 69.3 80.2 49.5 99.8 27.1 206.1 126.8 84.1 24.7 199.2 30.5 61.7 73.2 228.0 82.6 70.1 193.9 34.7 56.4 81.8 74.2 32.2 23.0 95.8 86.0 108.0 217.4 152.6 135.4 121.7 41.9 45.3 85.5 61.4 78.5 165.6 153.4 52.8 58.7 115.6 51.2 142.5 397.0 82.2 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Endothelial cells: 25.9;granulocytes: 29.1;Macrophages: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 20.0 7.1 8.4 20.3 8.7 30.7 12.1 8.6 12.7 9.0 9.6 11.0 11.0 6.0 2.0 15.6 8.0 11.5 10.6 7.8 8.2 15.4 9.3 25.6 15.4 10.1 9.8 3.0 9.9 1.6 3.7 9.2 9.3 8.4 11.4 0.3 13.3 4.3 3.1 4.9 14.4 7.6 9.1 36.1 10.8 1.2 10.3 6.7 8.7 3.1 13.8 12.3 11.5 9.6 13.5 24.4 0.1 0.1 6.0 12.4 0.2 17.0 14.8 15.4 22.4 13.9 26.6 0.3 19.1 14.2 13.7 21.7 4.3 24.9 5.8 8.3 0.6 18.8 17.6 16.2 4.2 12.3 18.6 8.5 2.4 16.8 5.7 9.0 37.3 21.3 2.7 2.5 11.9 22.0 7.0 24.3 2.2 29.3 30.0 13.5 1.8 23.8 22.0 10.2 1.0 0.8 13.4 8.7 7.2 0.1 6.2 12.5 41.4 7.8 4.8 7.0 11.7 11.2 40.2 3.2 13.7 42.3 3.9 21.9 36.2 45.8 11.2 22.2 15.4 8.1 12.6 12.0 18.9 6.7 6.8 10.4 48.6 3.6 23.3 1.2 17.4 16.0 8.4 8.7 8.6 12.7 7.8 8.2 10.1 9.8 9.3 9.1 10.3 9.6 32.1 3.2 10.7 1.0 9.8 3.4 6.8 3.1 7.4 0.2 3.3 3.4 3.1 2.8 5.5 1.8 0.0 0.2 9.6 8.9 1.9 4.6 3.5 1.2 1.9 25.9 1.2 3.4 0.5 5.2 0.8 7.1 15.3 1.6 29.1 0.3 16.8 1.3 16.6 1.7 0.5 10.9 0.0 18.2 7.8 5.2 0.9 28.9 7.2 11.2 16.7 0.1 11.3 1.5 5.2 4.9 9.4 0.4 18.5 2.8 5.5 0.6 2.0 0.6 0.0 3.0 3.1 0.1 0.2 13.4 2.8 0.3 16.5 0.2 9.5 7.5 MLPH "exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a" ENSG00000115648 Melanophilin Q9BV36 2 237485428-237555322 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 135.9;salivary gland: 122.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 125.0;Alveolar cells type 2: 389.7;Gastric mucus-secreting cells: 251.8;granulocytes: 187.3;Intestinal goblet cells: 189.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 142.9;MCF7: 255.4;SK-BR-3: 234.5;SK-MEL-30: 182.2;U-87 MG: 236.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA014685 Enhanced NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA014685: AB_1853997" "unprognostic (3.32e-3)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "prognostic favorable (5.14e-6)" "unprognostic (2.26e-4)" "unprognostic (1.36e-2)" "unprognostic (5.44e-2)" "unprognostic (2.66e-1)" "unprognostic (3.74e-3)" "unprognostic (8.16e-2)" "unprognostic (5.73e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.34e-1)" "unprognostic (9.37e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-3)" 13.2 1.4 0.6 2.4 0.7 0.1 56.9 0.7 1.6 69.3 1.3 20.4 8.8 18.1 8.9 6.4 18.0 31.0 69.2 1.1 0.7 4.3 39.0 62.7 0.6 1.1 1.0 11.8 16.1 9.0 2.1 1.9 0.8 135.9 21.7 0.3 122.0 13.0 6.6 11.6 15.2 2.8 0.6 0.2 98.1 2.5 0.8 0.9 39.9 2.5 1.2 22.1 21.9 0.9 0.3 133.7 0.3 0.3 58.5 39.5 0.4 26.8 31.5 14.7 18.5 1.1 101.1 0.2 0.1 49.6 51.0 0.3 0.1 0.9 13.0 0.1 0.3 0.1 0.1 0.0 23.3 0.1 0.7 48.1 14.7 43.4 56.2 75.6 0.1 0.0 0.1 0.3 142.9 255.4 0.4 0.6 0.4 105.4 77.1 0.5 0.1 0.2 0.5 3.2 1.5 0.2 0.1 234.5 182.2 0.7 61.5 1.7 26.8 80.1 2.3 0.9 38.0 0.2 0.2 0.2 236.0 0.1 63.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.7 1.6 1.1 0.7 1.1 1.0 0.8 0.6 0.8 0.9 12.3 125.0 389.7 0.0 0.8 4.1 17.3 6.0 0.0 0.0 95.6 59.7 63.2 52.9 64.2 12.9 0.0 0.4 0.7 34.9 1.9 12.0 0.2 9.5 10.1 10.1 14.4 0.0 0.2 41.3 0.3 4.5 251.8 17.5 187.3 0.2 1.4 28.8 1.2 0.0 0.1 189.0 32.6 0.8 2.9 0.7 8.4 7.4 30.2 5.6 0.6 0.0 0.0 0.0 0.0 58.1 22.4 3.0 0.8 54.4 9.1 0.6 48.5 0.0 0.0 3.1 3.7 0.3 0.6 1.2 2.4 0.7 6.1 0.4 30.5 38.6 MLX "bHLHd13, MAD7, MXD7, TCFL4" ENSG00000108788 "MAX dimerization protein MLX" Q9UH92 17 42567072-42573239 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025329, HPA052766, HPA064438" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear membrane, Cytosol" "CAB025329: , HPA052766: AB_2681940, HPA064438: AB_2685265" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.21e-3)" "unprognostic (3.88e-1)" "unprognostic (2.46e-2)" "unprognostic (8.55e-3)" "unprognostic (2.49e-1)" "unprognostic (4.87e-2)" "unprognostic (8.66e-2)" "unprognostic (9.66e-2)" "unprognostic (2.89e-1)" "unprognostic (1.61e-2)" "unprognostic (7.43e-2)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (3.25e-1)" 31.3 28.0 15.8 21.7 16.4 16.4 26.2 16.6 18.0 19.3 19.1 38.5 47.5 15.7 16.6 29.1 17.2 20.3 55.5 16.2 16.9 28.7 51.5 27.9 27.5 16.9 15.9 14.8 32.7 19.6 18.8 21.5 16.8 18.2 38.8 9.3 24.7 18.1 74.4 25.6 42.2 20.3 16.7 24.1 35.4 8.1 16.8 30.1 24.8 86.4 29.4 27.9 20.8 17.2 36.8 41.5 32.1 33.1 48.0 55.3 22.0 53.5 47.5 57.1 51.4 38.0 37.5 43.6 36.8 46.4 51.6 54.4 59.4 34.8 50.0 35.2 55.5 45.4 27.2 43.1 56.3 61.6 63.4 47.9 38.4 45.6 41.8 38.9 42.9 52.2 50.7 38.3 66.2 49.3 87.0 31.3 22.9 90.9 37.3 39.2 66.1 47.5 46.8 44.7 49.9 24.6 23.9 31.2 61.8 42.5 63.3 72.1 30.2 50.7 32.5 55.7 80.8 38.7 47.2 41.2 56.5 39.2 60.8 43.3 64.0 91.4 34.2 80.1 37.6 35.2 35.0 34.6 66.5 30.2 30.5 31.1 82.7 33.7 90.9 35.7 48.0 68.3 15.8 16.4 16.6 18.0 16.2 16.9 16.9 15.9 16.8 16.7 16.8 17.2 31.6 67.3 69.8 9.4 35.6 41.9 28.1 41.5 33.0 29.4 39.8 30.4 24.1 40.0 47.2 27.6 25.0 37.8 35.8 97.7 60.7 48.9 19.1 30.5 29.1 28.2 25.8 42.7 8.0 68.9 49.5 26.0 55.5 26.3 46.7 18.7 27.8 49.7 68.6 25.2 8.1 46.9 30.5 63.4 62.3 24.5 35.1 59.5 32.0 7.5 58.3 13.1 51.5 5.5 7.1 77.5 86.4 31.2 61.8 24.4 132.3 62.1 30.4 31.7 52.6 22.9 31.4 9.3 41.2 45.2 49.9 44.1 38.3 48.0 54.2 36.4 MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 609.7" "Group enriched" "Detected in many" 4 "Cholangiocytes: 84.4;Enteroendocrine cells: 90.1;Hepatocytes: 286.6;Proximal enterocytes: 108.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 46.5;K-562: 15.2;SCLC-21H: 25.5;T-47d: 11.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" 72.3 85.1 5.5 0.7 4.1 0.2 51.2 16.3 9.4 3.0 0.2 7.8 58.8 0.6 16.3 3.4 12.9 5.5 3.5 4.5 1.4 36.2 609.7 2.7 0.0 5.6 1.4 4.9 23.1 6.3 13.4 0.0 6.1 3.7 1.5 0.7 8.7 0.8 58.1 4.5 46.8 0.5 1.3 0.3 4.7 30.9 2.2 0.9 7.3 13.8 0.0 2.0 2.7 2.1 0.2 2.5 0.0 5.9 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 7.5 0.0 0.3 0.0 0.6 1.2 0.0 0.0 0.0 0.2 6.1 0.0 4.8 46.5 1.3 0.2 1.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.1 6.3 0.1 0.0 0.7 8.2 1.0 0.0 0.0 1.2 0.0 0.1 25.5 0.7 1.0 4.4 0.0 0.1 11.4 6.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 4.1 16.3 9.4 4.5 1.4 5.6 1.4 6.1 1.3 2.2 2.1 0.6 0.0 16.2 2.3 1.6 1.1 4.8 0.6 0.6 9.9 1.4 1.3 3.4 84.4 4.7 3.7 20.9 0.1 0.3 3.2 1.9 2.9 3.2 0.7 0.2 2.5 90.1 16.0 33.4 1.0 0.1 6.5 4.6 0.8 0.0 0.1 12.8 286.6 0.4 1.7 29.1 19.6 0.0 11.2 1.5 1.2 2.8 2.8 7.2 30.9 0.2 2.0 1.0 2.0 0.9 1.4 13.9 1.2 0.1 2.2 108.9 14.1 3.2 6.5 0.0 23.9 1.0 5.1 1.1 0.5 0.9 0.5 1.7 0.0 31.9 4.0 MLYCD "hMCD, MCD" ENSG00000103150 "Malonyl-CoA decarboxylase" O95822 16 83899115-83951445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 21.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 97.5;Cone photoreceptor cells: 125.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031625 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA031625: AB_10602028" "unprognostic (6.23e-2)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (6.23e-2)" "unprognostic (1.84e-4)" "unprognostic (2.33e-1)" "prognostic favorable (2.61e-7)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (9.56e-2)" "unprognostic (1.51e-3)" 2.5 2.1 1.9 1.0 2.5 0.4 1.4 1.5 2.4 1.1 2.7 1.7 1.7 1.3 1.2 1.0 1.4 0.7 9.5 1.7 1.9 2.7 5.7 1.2 1.2 2.5 2.5 1.9 5.1 2.0 1.2 0.9 2.0 1.2 1.7 2.4 2.1 1.5 8.2 1.0 1.4 1.2 1.6 1.0 2.5 1.3 3.2 1.0 1.5 21.5 0.9 1.6 0.9 2.5 0.6 1.9 1.6 1.9 2.5 0.9 2.9 0.8 1.2 0.7 0.4 0.9 1.5 0.1 2.4 1.2 2.6 1.5 1.4 0.6 0.7 0.8 1.9 0.9 0.8 1.9 3.0 1.2 2.1 1.1 1.4 0.4 0.4 1.3 0.8 1.4 1.4 0.4 1.1 2.4 0.7 2.7 1.6 2.7 0.4 2.2 1.1 1.1 1.6 1.1 1.4 0.9 3.0 1.1 2.4 2.1 3.4 2.5 0.6 1.8 0.3 1.0 0.2 2.1 1.3 2.0 1.0 0.9 1.9 0.5 0.1 0.5 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.9 2.5 1.5 2.4 1.7 1.9 2.5 2.5 2.0 1.6 3.2 2.5 6.1 6.4 7.3 8.5 10.9 2.0 7.4 1.5 4.6 25.2 7.2 5.2 97.5 17.2 5.5 23.9 125.1 20.2 10.6 12.9 31.3 5.7 4.6 10.4 6.9 8.2 10.2 9.1 3.1 5.5 11.1 10.5 15.3 8.7 5.7 20.1 12.8 46.2 12.3 16.8 6.2 15.2 4.1 10.1 2.0 8.6 14.6 8.2 3.6 3.7 7.7 14.7 27.8 12.5 8.2 6.7 13.1 19.5 6.5 10.4 19.4 19.4 2.4 53.3 6.6 19.0 8.1 12.1 14.4 5.2 2.0 8.2 9.0 17.5 17.1 8.6 MMD "MMA, PAQR11" ENSG00000108960 "Monocyte to macrophage differentiation associated" Q15546 17 55392622-55421924 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 152.2;brain: 87.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 56.4;Macrophages: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 110.0;HSkMC: 199.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026978 Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA026978: AB_2672068" "unprognostic (1.33e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.52e-5)" "prognostic unfavorable (3.88e-4)" "unprognostic (2.48e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (6.39e-5)" "unprognostic (8.07e-3)" "unprognostic (6.67e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (3.71e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.12e-2)" 152.2 13.3 54.2 15.7 55.9 14.1 28.4 11.6 58.5 4.8 5.4 13.4 10.9 6.2 9.7 7.2 4.2 9.4 6.5 87.5 19.7 8.5 13.2 10.0 17.8 16.3 29.2 2.8 3.5 3.7 4.8 21.4 16.1 6.2 12.9 12.8 4.9 7.9 3.4 5.3 10.1 11.4 24.2 16.5 5.4 17.0 21.6 8.2 6.6 8.0 12.1 11.6 4.0 27.2 20.1 46.3 67.0 13.5 110.0 86.0 39.2 13.6 5.2 7.2 10.2 7.4 53.8 30.1 39.6 4.5 20.1 1.5 18.8 14.3 14.9 41.5 9.5 11.0 2.5 85.2 29.8 10.8 3.2 199.4 4.5 10.1 11.4 15.7 9.0 27.4 4.4 20.5 15.1 2.8 29.7 8.2 20.6 3.3 15.6 12.4 46.9 10.0 19.7 5.0 7.0 72.8 5.0 7.1 10.9 41.5 15.4 17.3 9.6 18.7 26.6 15.5 14.0 13.1 6.2 45.7 26.7 8.5 15.2 14.2 1.5 1.9 1.7 2.1 4.9 4.5 1.8 3.3 4.3 5.0 3.1 3.3 4.6 2.9 1.9 1.3 2.1 17.5 54.2 55.9 11.6 58.5 87.5 19.7 16.3 29.2 16.1 24.2 21.6 27.2 15.5 3.2 0.6 5.2 20.3 5.4 23.7 9.3 5.2 28.2 3.3 3.3 4.6 11.5 2.7 7.3 4.2 11.5 12.2 3.4 15.6 27.7 2.5 4.8 8.9 16.4 7.8 27.3 36.5 1.3 18.8 12.7 2.6 8.7 0.0 3.5 19.6 17.9 37.6 16.8 11.5 6.8 8.2 56.4 35.9 4.0 1.8 85.9 7.2 14.0 48.6 14.5 12.3 7.5 7.2 17.3 1.6 3.4 12.1 26.2 2.3 9.8 2.4 10.2 19.7 5.2 11.4 28.9 23.3 3.1 17.5 20.0 17.7 1.3 8.6 6.1 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.0;Pancreatic endocrine cells: 144.7;Syncytiotrophoblasts: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 923.8;HHSteC: 794.2;HSkMC: 887.0;hTERT-RPE1: 925.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 151.5 31.7 5.6 59.9 5.0 1.6 101.5 5.7 7.5 181.3 61.8 77.2 39.5 167.3 19.0 92.1 82.1 148.2 41.3 6.6 7.2 35.9 13.2 91.8 24.8 11.9 8.4 90.2 36.0 65.3 14.2 118.9 9.2 59.9 36.6 9.6 78.1 45.5 18.8 127.5 69.4 106.0 7.3 30.8 57.7 11.7 13.2 13.0 50.0 16.1 30.8 103.9 111.1 10.6 90.6 1.2 26.3 2.0 923.8 651.6 455.9 270.1 606.4 93.3 158.5 21.3 337.4 0.9 146.4 301.9 24.6 216.3 0.3 262.2 99.7 1.1 0.6 37.2 1.7 5.0 794.2 0.4 1.3 887.0 148.7 334.7 288.3 925.5 492.9 0.6 0.8 2.1 185.1 0.7 0.4 79.4 14.7 17.7 52.4 2.1 96.0 0.2 61.4 148.1 0.3 0.6 187.3 0.3 574.2 104.4 1.0 79.5 436.8 724.9 53.7 198.2 329.6 0.8 1.6 1.1 410.9 0.6 396.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 5.0 5.7 7.5 6.6 7.2 11.9 8.4 9.2 7.3 13.2 10.6 13.9 12.8 3.0 2.0 3.4 34.0 23.4 105.4 39.3 0.0 14.1 17.5 4.7 50.1 42.2 7.3 0.0 105.6 0.3 19.9 11.7 63.0 0.4 16.1 81.6 35.2 7.8 0.0 0.0 28.7 244.0 84.0 25.5 14.8 3.8 9.3 32.9 2.7 89.5 0.0 0.0 24.5 34.6 20.2 32.7 2.4 72.1 38.0 37.4 4.7 21.5 14.3 0.0 0.5 0.1 144.7 33.0 54.9 0.3 21.8 19.9 11.7 46.8 0.8 39.5 11.1 73.9 0.8 0.8 33.7 34.2 122.7 2.5 15.6 18.6 37.9 MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.8;Distal enterocytes: 109.3;Proximal enterocytes: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 93.6;Hep G2: 51.1;OE19: 44.6;SK-BR-3: 47.3;WM-115: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" 11.9 3.8 8.9 4.4 6.0 0.4 7.6 7.3 11.2 5.7 5.8 28.0 40.2 3.5 1.1 4.6 6.1 14.3 41.2 6.9 8.7 14.9 50.1 9.9 2.1 15.8 10.6 1.1 18.5 12.7 8.8 28.4 16.8 4.4 14.3 1.5 8.4 9.5 7.0 4.3 33.0 3.7 5.8 9.3 29.6 34.9 18.7 1.0 46.7 5.6 1.3 5.1 2.8 8.6 15.3 11.4 5.8 30.4 6.0 0.3 93.6 1.4 0.8 5.4 1.2 9.1 38.3 0.2 17.7 1.6 4.2 21.0 5.1 4.4 1.6 0.1 10.0 0.1 4.9 51.1 7.7 0.3 19.5 3.1 7.8 0.9 2.3 8.4 3.7 8.5 12.9 0.1 1.8 7.6 0.7 2.6 17.2 44.6 3.2 7.6 0.7 8.3 16.6 5.4 1.6 10.4 20.0 47.3 9.5 13.2 5.2 8.2 3.4 0.4 9.1 3.5 1.3 0.2 0.1 0.3 1.9 2.3 78.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.9 6.0 7.3 11.2 6.9 8.7 15.8 10.6 16.8 5.8 18.7 8.6 14.3 19.2 14.4 9.1 0.7 2.5 1.0 4.9 2.8 3.4 5.0 3.0 24.7 55.8 12.6 18.4 16.7 48.2 1.6 109.3 1.9 35.7 5.0 3.6 1.1 17.2 11.4 2.7 1.4 12.0 49.2 4.5 35.2 6.4 0.0 18.6 13.6 39.2 12.9 1.7 1.2 33.3 10.2 3.0 0.3 6.9 0.9 0.9 1.8 1.0 0.0 2.1 0.0 4.5 1.4 13.3 38.5 3.4 0.3 1.3 67.3 7.3 6.0 1.9 0.0 0.7 2.4 0.9 4.6 3.3 2.3 48.4 0.7 23.2 45.0 1.7 MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.4;Fibroblasts: 52.8;Hofbauer cells: 30.8;Kupffer cells: 35.7;Langerhans cells: 100.7;Macrophages: 61.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 75.6" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "HPA070804: AB_2686315" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" 58.5 3.6 0.0 11.4 0.1 0.7 18.3 0.0 0.3 10.4 0.5 7.3 1.2 20.7 0.5 2.3 17.2 25.6 8.8 0.1 0.1 5.7 2.7 25.4 2.8 0.1 0.1 11.9 7.2 0.5 0.8 10.8 0.2 3.3 3.3 0.1 3.1 2.3 0.9 5.5 8.7 8.7 0.1 27.4 9.6 0.4 1.3 2.9 4.4 0.6 6.9 9.6 6.2 0.1 1.5 0.0 0.2 0.0 7.8 12.4 75.6 10.1 10.6 3.9 4.4 0.6 0.6 0.0 0.0 12.8 0.3 0.0 0.0 3.0 4.0 0.8 0.0 0.0 0.3 0.1 6.5 0.0 0.6 12.1 0.4 1.9 2.4 6.2 0.7 0.0 0.2 0.1 11.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 2.8 0.0 1.7 4.7 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.2 15.7 2.2 5.0 0.2 0.3 0.1 0.0 0.0 8.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.2 0.1 1.3 0.1 2.8 0.0 4.6 0.7 1.3 7.1 0.3 1.9 0.6 0.4 0.3 0.3 0.7 11.5 3.3 0.0 4.2 18.6 0.7 0.0 0.0 0.3 0.5 2.4 20.8 1.5 0.0 0.0 0.2 0.5 54.4 52.8 1.1 1.7 2.5 0.4 3.6 0.7 30.8 0.0 0.2 0.1 0.0 35.7 100.7 0.9 5.9 61.2 12.4 1.9 22.5 0.4 0.0 0.0 0.3 0.1 0.0 5.3 1.0 0.3 0.0 0.1 1.5 1.7 0.0 3.8 7.6 0.2 0.2 1.0 4.3 18.7 0.9 0.2 0.0 0.4 MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 90.5;Leydig cells: 98.2;NK-cells: 64.9;Peritubular cells: 177.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cell line enhanced" "Detected in some" "HHSteC: 4.4;NTERA-2: 2.7;PC-3: 1.9;U-266/70: 3.9" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" 7.1 2.8 0.4 0.3 0.5 1.3 4.1 0.1 1.0 16.7 0.0 5.0 1.9 15.4 0.0 2.8 11.0 2.9 15.0 0.3 0.0 3.2 3.3 14.3 1.1 0.4 0.0 29.9 1.6 0.0 5.7 2.8 0.1 11.8 0.1 0.1 1.0 1.1 0.5 3.1 3.4 1.2 0.0 3.0 4.3 5.2 0.1 0.0 2.4 0.0 0.1 11.9 10.9 0.2 0.6 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.4 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.5 0.2 1.2 4.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.4 0.0 0.2 2.7 0.0 1.9 0.9 0.0 1.1 0.0 0.0 0.4 0.2 0.3 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.3 0.0 3.9 0.2 1.1 0.0 0.2 0.1 0.0 0.2 0.0 1.5 0.0 0.9 0.0 0.3 1.0 0.0 0.1 0.0 0.7 0.1 2.2 0.1 11.3 0.3 1.7 0.4 0.5 0.1 1.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.2 2.2 0.0 0.5 1.0 1.1 13.4 0.8 0.7 0.6 1.3 1.7 1.5 9.6 1.5 0.4 1.8 0.0 4.0 27.4 3.0 0.0 1.2 1.0 4.0 3.5 2.2 3.0 2.7 0.3 0.5 2.2 90.5 4.6 1.0 0.0 1.4 12.1 1.0 5.7 3.3 0.6 1.9 4.1 1.0 18.5 6.2 98.2 1.3 19.6 0.0 1.2 0.5 64.9 0.0 0.2 4.3 0.9 177.9 4.3 0.5 2.7 1.0 0.5 7.7 0.0 0.7 5.3 2.1 10.5 0.7 15.8 10.3 8.1 2.1 1.7 0.9 MMP27 ENSG00000137675 "Matrix metallopeptidase 27" Q9H306 11 102691487-102705769 "Enzymes, Predicted intracellular proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.7;salivary gland: 1.9;skin 1: 2.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Fibroblasts: 4.2;Langerhans cells: 1.8;Suprabasal keratinocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA069097 Approved "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 50: Fibroblasts - ECM organization" "HPA069097: AB_2686085" "unprognostic (3.99e-2)" "unprognostic (2.37e-4)" "unprognostic (1.25e-3)" "unprognostic (1.63e-1)" "unprognostic (4.60e-1)" 1.2 0.0 0.0 0.0 0.0 1.3 4.7 0.0 0.0 0.2 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.4 2.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MN1 "MGCR, MGCR1, MGCR1-PEN" ENSG00000169184 "MN1 proto-oncogene, transcriptional regulator" Q10571 22 27748277-27801756 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.7;skeletal muscle: 61.6;tongue: 42.6" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Early spermatids: 22.3;Fibroblasts: 13.9;Langerhans cells: 11.2;Late spermatids: 15.2;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 30.7;HeLa: 12.7;hTERT-RPE1: 13.7;RH-30: 12.4;TIME: 20.1;U-2 OS: 16.3;U-2197: 17.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003072 Approved Approved Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003072: AB_1079399" "unprognostic (5.64e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-2)" "unprognostic (2.52e-2)" "unprognostic (7.01e-2)" "unprognostic (3.03e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (4.00e-2)" "unprognostic (7.33e-2)" "unprognostic (5.13e-7)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.28e-3)" "unprognostic (2.21e-4)" 4.1 0.8 6.0 1.6 20.7 1.3 2.3 6.4 9.5 2.2 0.5 6.1 0.8 2.7 1.0 3.6 4.3 3.0 6.7 1.9 5.3 0.9 0.4 3.3 0.1 4.3 13.0 9.6 0.7 0.1 2.7 1.3 6.8 2.3 0.9 1.8 2.7 1.2 61.6 1.8 2.1 2.5 2.1 0.4 4.0 0.8 8.5 0.3 2.1 42.6 0.7 3.3 3.5 3.1 0.0 1.5 30.7 0.9 0.6 1.3 0.0 0.7 1.1 0.0 0.0 0.0 0.1 0.0 3.1 5.7 1.3 2.7 1.5 1.8 0.0 0.0 0.8 0.0 12.7 0.0 0.7 0.0 0.3 0.1 3.5 0.7 3.0 13.7 0.3 0.0 0.0 0.2 1.0 0.0 0.0 0.4 4.0 0.0 2.8 5.3 12.4 0.0 0.4 0.0 0.1 0.4 2.7 0.0 0.0 7.5 0.3 0.1 20.1 1.0 16.3 17.9 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.0 20.7 6.4 9.5 1.9 5.3 4.3 13.0 6.8 2.1 8.5 3.1 2.1 3.2 2.3 12.1 0.3 4.2 0.1 2.6 3.4 8.4 1.8 0.6 7.4 1.5 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.4 22.3 1.4 1.0 6.6 0.0 0.0 6.4 1.0 0.1 13.9 0.5 3.1 0.0 0.6 2.5 0.6 0.3 0.0 9.6 0.0 2.0 1.4 11.2 15.2 5.0 2.7 0.0 2.8 0.3 3.9 0.0 13.0 4.3 2.8 0.0 10.1 1.3 0.2 0.0 0.1 0.1 0.7 0.0 2.4 2.3 0.4 1.1 1.9 2.7 0.0 0.3 0.4 0.0 0.2 MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671658-222709930 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "gallbladder: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Breast glandular cells: 7.2;Cholangiocytes: 7.2;Endometrial ciliated cells: 3.9;Exocrine glandular cells: 5.1;Glandular and luminal cells: 4.9;Hepatocytes: 3.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049944, HPA076308" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "Endoplasmic reticulum" "HPA049944: AB_2680964, HPA076308: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" 0.9 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.0 16.8 0.4 0.1 0.1 0.8 3.1 0.4 0.0 0.1 0.6 0.0 0.2 0.6 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.1 0.4 0.6 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.3 0.7 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.9 3.9 0.6 0.1 0.0 0.0 2.5 5.1 0.0 0.1 0.0 4.9 0.0 0.2 0.0 3.2 0.9 0.0 1.9 0.0 0.0 0.3 0.3 0.1 0.0 1.3 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.9 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 MORF4L1 "Eaf3, HsT17725, MEAF3, MORFRG15, MRG15" ENSG00000185787 "Mortality factor 4 like 1" Q9UBU8 15 78810487-78898139 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042360, HPA062010" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA042360: AB_10794275, HPA062010: AB_2684655" "unprognostic (5.36e-2)" "unprognostic (4.30e-1)" "unprognostic (3.68e-1)" "unprognostic (9.69e-2)" "unprognostic (1.27e-1)" "unprognostic (1.83e-3)" "unprognostic (3.61e-3)" "unprognostic (8.61e-3)" "unprognostic (3.15e-1)" "unprognostic (3.58e-2)" "unprognostic (6.96e-2)" "unprognostic (3.69e-1)" "unprognostic (5.77e-2)" "unprognostic (1.17e-1)" "unprognostic (2.12e-1)" "unprognostic (3.92e-2)" "unprognostic (2.60e-3)" 272.8 306.3 183.9 237.6 193.6 427.6 241.5 197.6 285.5 283.8 188.9 270.1 169.4 305.1 213.0 201.1 257.9 256.5 396.6 187.9 240.5 332.2 258.9 243.4 251.8 232.8 221.6 318.2 165.5 263.6 175.1 300.9 223.4 228.7 225.7 265.5 195.9 282.7 559.3 140.5 187.4 331.5 205.4 217.4 186.9 588.7 220.1 297.6 270.2 425.2 279.6 266.2 184.3 227.9 362.0 480.3 863.5 355.4 603.2 620.4 453.2 644.3 636.0 570.7 554.0 436.9 532.7 446.7 517.2 649.1 376.0 442.1 1054.3 432.8 534.3 446.0 420.3 493.5 483.5 406.5 617.9 410.4 424.3 436.7 482.5 323.1 447.6 550.1 689.1 309.7 526.3 398.2 659.2 335.3 392.9 301.6 930.7 472.9 208.5 431.8 673.0 431.0 459.2 488.1 443.6 457.7 578.1 367.2 825.7 871.1 441.7 533.9 543.1 667.2 471.6 359.0 549.6 256.4 770.6 499.2 412.3 647.4 501.4 118.5 195.0 197.5 123.0 188.4 149.4 172.7 176.9 141.6 225.5 163.7 241.9 174.2 154.9 145.1 155.8 214.4 214.2 318.6 183.9 193.6 197.6 285.5 187.9 240.5 232.8 221.6 223.4 205.4 220.1 227.9 374.2 301.3 249.0 38.2 300.0 418.1 624.1 724.2 256.6 104.5 236.1 198.9 372.2 286.0 512.3 290.6 62.6 611.9 309.4 173.4 686.7 545.5 740.6 377.8 352.6 391.1 275.2 298.0 69.6 312.8 815.0 468.2 153.4 282.5 465.8 179.5 372.3 328.6 379.1 200.2 68.5 263.6 451.6 310.9 601.3 504.6 389.5 325.7 501.6 52.5 450.8 322.0 306.9 40.2 80.0 407.4 185.5 464.9 232.0 489.8 178.6 805.1 582.5 97.5 315.5 368.3 500.6 1322.3 467.9 185.3 370.4 663.0 338.2 279.9 199.0 597.1 MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 207.4" "Group enriched" "Detected in some" 4 "dendritic cells: 156.0;Kupffer cells: 409.8;Macrophages: 174.6;monocytes: 218.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 290.5;intermediate monocyte: 209.9;myeloid DC: 144.7;non-classical monocyte: 245.2;plasmacytoid DC: 204.9" "Group enriched" "Detected in many" 6 "dendritic cells: 204.9;monocytes: 290.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA046801 Approved "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" 29.2 15.8 1.5 112.4 1.6 21.3 13.5 1.7 2.4 11.6 3.2 32.9 40.9 10.9 3.7 12.6 6.9 36.2 10.3 1.4 2.1 6.0 41.1 35.4 96.3 3.3 1.9 4.9 4.6 4.6 1.6 35.8 2.5 8.0 43.4 0.3 7.3 9.3 3.9 7.1 52.8 28.2 2.9 207.4 19.2 4.5 4.0 42.8 5.9 8.3 75.2 42.7 2.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 290.5 8.4 0.5 209.9 0.5 12.6 0.3 0.2 144.7 14.0 0.2 0.1 38.5 1.2 245.2 204.9 0.6 214.5 1.5 1.6 1.7 2.4 1.4 2.1 3.3 1.9 2.5 2.9 4.0 4.0 0.7 0.0 7.9 0.0 33.8 1.1 0.0 0.0 1.2 0.0 0.3 0.9 1.7 1.5 0.6 0.0 0.0 0.3 156.0 0.1 0.0 0.0 0.2 0.0 0.1 1.7 0.0 4.4 0.0 0.0 0.6 0.8 0.5 0.1 2.5 0.0 4.6 3.7 52.4 0.0 0.0 0.0 0.0 409.8 48.0 0.6 0.0 174.6 1.8 10.3 218.2 0.2 7.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 6.6 0.7 0.4 0.0 0.0 0.3 1.6 0.3 2.7 0.0 0.0 0.1 MPHOSPH6 MPP6 ENSG00000135698 "M-phase phosphoprotein 6" Q99547 16 82147798-82170224 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003674, HPA026948" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli" "CAB003674: , HPA026948: AB_1854077" "unprognostic (2.58e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-1)" "unprognostic (2.97e-3)" "prognostic unfavorable (4.36e-5)" "unprognostic (2.00e-2)" "unprognostic (2.29e-3)" "prognostic favorable (3.41e-5)" "unprognostic (7.52e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (3.05e-1)" "unprognostic (2.95e-1)" "unprognostic (2.11e-1)" "unprognostic (1.17e-1)" "unprognostic (9.43e-2)" 19.8 21.3 26.7 25.5 26.8 20.0 72.5 29.6 32.8 23.6 19.1 22.7 13.8 25.8 22.4 36.2 15.9 16.5 13.9 26.7 28.3 17.8 15.9 18.7 24.7 22.1 24.7 13.4 9.0 16.2 21.3 24.4 23.1 15.3 24.9 31.6 26.0 13.0 18.0 40.1 15.9 22.8 21.7 16.7 15.7 14.1 27.5 20.7 11.6 17.5 26.2 34.7 21.0 28.4 67.8 36.2 79.0 38.9 37.7 52.7 43.5 71.1 84.7 60.6 29.3 58.5 38.4 55.2 42.0 39.2 44.7 69.2 76.2 73.6 80.8 41.3 49.9 44.5 31.2 106.5 37.5 111.9 65.9 33.6 64.7 36.2 102.8 30.5 70.6 75.7 106.2 15.3 93.4 54.8 86.5 131.2 72.4 83.4 49.5 105.5 36.6 36.5 55.3 69.8 54.1 23.3 119.6 52.5 53.6 32.4 92.2 68.6 56.0 56.5 56.3 50.2 51.3 22.4 58.0 217.9 51.0 89.9 73.2 26.1 38.3 36.9 38.2 46.5 48.5 35.6 38.7 39.9 44.9 29.2 41.1 38.8 4.9 33.1 33.8 27.2 44.3 28.3 26.7 26.8 29.6 32.8 26.7 28.3 22.1 24.7 23.1 21.7 27.5 28.4 13.2 19.2 38.3 20.5 22.9 38.7 40.3 123.9 19.4 14.5 74.3 50.0 31.5 14.3 66.2 20.2 10.4 56.9 23.0 21.7 50.9 45.2 6.5 13.9 18.5 19.3 9.0 23.1 38.5 28.1 46.1 31.4 15.8 22.0 18.3 21.9 20.0 19.0 49.6 20.2 35.6 20.7 40.7 29.1 42.7 7.5 11.1 55.9 32.0 12.2 56.0 61.1 34.0 29.7 17.1 56.4 28.4 10.1 22.3 38.6 12.2 46.5 32.7 24.5 19.7 15.4 30.1 36.9 57.5 30.6 54.0 32.8 27.4 26.3 34.0 48.1 MPP1 "DXS552E, PEMP" ENSG00000130830 "Membrane palmitoylated protein 1" Q00013 X 154778684-154821007 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 116.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 410.9;Erythroid cells: 393.8;Hofbauer cells: 291.9;Macrophages: 155.9;Syncytiotrophoblasts: 454.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 215.7;neutrophil: 202.1" "Group enriched" "Detected in all" 8 "dendritic cells: 57.7;granulocytes: 215.7;monocytes: 98.8" "Cell line enhanced" "Detected in many" "HEL: 218.0;REH: 136.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076675 Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 650000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Centriolar satellite" "HPA076675: " "unprognostic (2.15e-1)" "unprognostic (4.06e-2)" "unprognostic (4.52e-2)" "unprognostic (1.83e-3)" "unprognostic (7.14e-2)" "unprognostic (2.60e-2)" "unprognostic (7.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (7.79e-2)" "unprognostic (3.77e-3)" "unprognostic (1.70e-3)" "prognostic favorable (4.60e-6)" "unprognostic (6.69e-2)" "unprognostic (2.53e-2)" "unprognostic (4.68e-2)" "unprognostic (6.67e-3)" 24.1 27.2 21.0 27.1 22.0 116.8 16.5 26.2 29.7 11.6 18.6 17.2 59.4 13.4 5.3 10.5 15.7 24.3 26.0 22.5 25.2 42.9 37.5 28.3 24.9 28.3 21.9 10.6 34.6 30.7 9.7 86.5 30.7 15.5 17.6 10.6 23.7 18.1 29.2 10.2 47.3 19.7 22.5 40.9 11.8 7.1 27.3 72.8 14.0 27.2 12.5 21.3 10.0 28.2 41.4 8.3 18.7 18.7 19.0 20.1 59.5 15.3 23.3 25.3 30.8 23.7 3.7 32.8 29.3 17.1 67.9 4.6 21.6 6.9 19.9 34.9 38.0 218.0 5.7 25.3 28.6 44.4 121.4 19.4 9.0 28.2 7.0 25.9 58.5 42.1 96.1 5.3 28.7 0.2 102.6 60.3 1.9 3.8 28.2 136.0 4.8 15.5 14.8 3.3 4.7 7.5 12.7 1.2 13.3 18.5 3.2 25.8 26.6 23.2 12.5 51.8 41.7 36.6 52.9 12.5 32.7 61.7 11.1 49.7 95.6 215.7 5.1 76.6 6.0 7.8 5.9 5.7 57.7 2.7 15.4 7.9 202.1 10.1 98.8 15.5 3.5 79.1 21.0 22.0 26.2 29.7 22.5 25.2 28.3 21.9 30.7 22.5 27.3 28.2 18.3 3.2 11.2 8.1 6.3 8.7 4.8 0.2 8.0 10.2 7.1 5.1 17.0 41.5 6.2 7.3 4.2 410.9 6.9 16.3 21.5 11.7 0.6 3.5 5.7 18.9 11.5 393.8 16.1 2.8 27.0 11.4 1.1 6.4 90.6 9.6 11.7 10.6 291.9 16.8 17.1 4.4 0.0 104.7 30.2 2.4 8.7 155.9 10.6 15.9 52.5 15.4 9.2 6.0 5.9 3.7 4.1 13.2 8.1 3.1 57.4 66.3 2.2 8.2 0.0 8.6 10.3 0.7 6.8 6.4 6.0 454.4 9.9 14.5 5.8 1.2 MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 390.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 553.6;Hepatocytes: 578.6;Paneth cells: 621.4;Proximal enterocytes: 1322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 2900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favorable (5.89e-4)" 58.0 57.3 25.3 10.0 32.3 36.5 51.0 29.0 31.0 40.9 29.8 102.4 106.5 34.7 0.6 91.5 42.9 16.6 64.2 22.9 23.4 71.4 390.7 43.5 8.8 34.0 27.5 81.7 106.4 4.8 14.7 9.1 29.7 45.3 17.0 0.5 43.5 9.6 89.7 82.3 93.0 7.0 26.0 22.1 70.3 51.7 31.4 4.5 24.8 23.1 6.0 48.3 62.3 35.1 44.0 50.4 24.2 50.0 27.8 17.2 38.1 23.4 20.6 24.8 33.2 48.6 18.9 68.7 33.0 16.7 16.7 29.9 20.9 33.8 3.6 41.4 119.2 26.5 21.3 115.6 87.5 29.0 35.6 30.0 64.2 16.1 15.1 22.8 50.6 33.1 48.0 19.3 7.0 33.8 2.6 97.5 45.7 56.7 52.2 73.6 28.8 51.9 25.5 14.0 12.4 92.9 15.6 23.9 46.6 12.2 26.0 45.6 39.8 21.3 60.1 23.9 16.0 33.3 16.8 21.0 7.7 34.7 11.1 48.5 71.9 54.7 31.0 27.5 42.4 24.9 20.1 26.4 104.0 25.0 2.7 10.4 21.9 87.8 12.7 16.3 44.3 35.4 25.3 32.3 29.0 31.0 22.9 23.4 34.0 27.5 29.7 26.0 31.4 35.1 21.3 35.3 61.9 14.7 25.1 81.6 80.4 120.3 70.6 4.5 81.4 83.4 29.4 243.1 70.0 60.7 0.0 61.9 20.3 553.6 133.1 146.4 191.1 38.5 46.8 42.6 108.6 122.6 1.1 148.3 119.1 52.8 87.1 72.5 17.2 140.3 108.5 578.6 77.5 3.3 1.9 363.1 85.5 84.6 77.6 115.1 91.0 62.7 58.7 3.7 60.7 24.8 56.7 4.5 14.9 117.9 621.4 84.7 65.7 77.7 1322.1 469.8 13.4 2.8 46.0 34.4 36.0 101.3 11.5 133.7 152.9 50.1 26.6 57.7 397.5 110.6 MRAP "B27, C21orf61, FALP" ENSG00000170262 "Melanocortin 2 receptor accessory protein" Q8TCY5 21 32291813-32314784 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "adipose tissue: 75.6;adrenal gland: 166.5;breast: 44.2" "Group enriched" "Detected in some" 5 "Early spermatids: 16.1;Granulosa cells: 43.7;Horizontal cells: 43.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 1.5;HSkMC: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011024, HPA011093" Uncertain Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA011024: AB_10599292, HPA011093: AB_10600889" "unprognostic (1.38e-1)" "unprognostic (1.55e-3)" "unprognostic (1.53e-1)" "unprognostic (1.11e-1)" "unprognostic (9.53e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.80e-2)" "unprognostic (4.12e-1)" "unprognostic (6.30e-6)" "unprognostic (3.32e-2)" "unprognostic (2.37e-1)" "unprognostic (1.18e-1)" "unprognostic (5.76e-2)" 75.6 166.5 0.1 1.8 0.1 0.0 44.2 0.0 0.5 0.1 0.8 1.2 0.2 0.0 0.0 0.1 0.0 0.6 2.0 0.1 0.0 0.3 2.4 1.0 0.1 0.2 0.0 2.0 0.7 0.0 0.1 1.7 0.1 0.0 0.2 1.0 2.0 0.0 0.2 1.3 3.5 0.1 0.0 0.0 0.6 0.5 0.0 0.1 0.7 0.2 0.0 1.4 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.7 0.2 0.4 0.2 0.8 0.2 0.5 0.0 1.9 0.1 0.5 0.7 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.4 0.0 0.1 0.0 0.0 0.7 0.0 0.1 1.3 0.0 0.0 0.0 43.7 0.0 1.7 0.1 43.7 0.6 0.0 0.0 0.0 0.0 6.6 0.6 0.1 0.0 0.0 0.0 0.3 0.0 2.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.6 1.6 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 MRAS "M-RAs, R-RAS3, RRAS3" ENSG00000158186 "Muscle RAS oncogene homolog" O14807 3 138347648-138405534 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 202.3;heart muscle: 132.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 121.7;Distal tubular cells: 58.7;Theca cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 9 "monocytes: 25.0" "Cell line enhanced" "Detected in many" "BJ: 92.9;EFO-21: 113.7;fHDF/TERT166: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042728 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Vesicles "HPA042728: AB_10796582" "unprognostic (1.96e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.69e-1)" "unprognostic (5.32e-2)" "unprognostic (8.96e-2)" "unprognostic (3.85e-3)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (3.18e-3)" "unprognostic (1.78e-2)" "unprognostic (6.25e-2)" "unprognostic (2.21e-1)" "unprognostic (4.23e-2)" 91.9 67.7 112.7 10.8 130.6 1.7 46.7 118.2 105.5 17.3 48.9 24.2 3.3 28.7 7.1 7.9 26.4 12.0 132.9 105.6 132.8 22.9 5.5 18.4 5.2 126.1 135.9 48.6 5.7 8.2 17.7 10.6 112.9 15.3 4.1 15.9 13.4 15.0 80.4 12.2 8.7 23.2 110.3 12.2 12.0 9.6 202.3 4.9 26.4 48.0 3.3 29.1 12.1 97.8 0.8 7.9 15.8 24.5 59.6 29.2 40.0 92.9 16.0 7.3 8.2 3.3 3.1 0.3 113.7 70.4 18.6 0.1 9.0 1.8 6.1 7.7 3.1 0.5 4.8 20.1 15.9 0.0 1.9 41.5 5.9 0.7 1.4 13.6 1.3 0.0 10.7 0.8 31.4 3.7 0.0 20.4 19.1 0.0 2.7 1.1 33.8 0.2 30.4 2.0 18.6 42.0 62.8 0.7 45.9 10.9 16.1 37.7 0.6 23.7 25.3 24.3 2.4 0.1 1.0 1.2 21.4 0.1 11.4 0.2 2.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.3 0.8 25.0 0.1 0.0 0.8 112.7 130.6 118.2 105.5 105.6 132.8 126.1 135.9 112.9 110.3 202.3 97.8 8.9 9.6 1.5 54.2 0.8 2.2 3.0 3.4 1.2 5.6 28.8 34.8 121.7 2.8 3.5 9.2 10.4 20.1 0.2 0.0 58.7 8.6 11.6 1.0 21.4 14.5 1.8 0.0 25.5 3.2 3.2 23.0 2.0 1.5 6.3 35.2 12.8 1.6 26.3 28.6 20.6 0.0 2.0 15.1 18.4 40.0 23.3 18.2 28.4 20.6 12.2 24.3 0.0 28.6 11.0 3.8 0.0 34.3 0.1 3.3 0.0 27.5 1.3 9.6 6.6 20.8 18.9 7.3 18.6 0.4 1.0 14.4 0.8 59.1 0.0 0.6 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 171.2;intestine: 159.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 33.3;Leydig cells: 66.2;Peritubular cells: 100.8;Sertoli cells: 52.6;Smooth muscle cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 67.6;ASC TERT1: 30.0;BJ: 39.5;BJ hTERT+: 99.1;BJ hTERT+ SV40 Large T+: 36.8;fHDF/TERT166: 30.8;U-2197: 46.8" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in some" "spinal cord: 4.8" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 41.7 3.8 2.6 12.8 2.9 0.0 32.5 12.0 3.9 103.6 5.5 159.2 9.3 171.2 14.2 16.2 98.0 16.7 13.7 2.4 3.1 17.1 7.0 18.7 4.5 4.7 2.8 37.0 3.4 0.5 4.1 11.6 3.3 48.3 8.9 0.2 10.8 45.6 5.1 15.2 38.3 59.3 2.8 13.4 44.1 7.3 2.8 0.7 10.7 3.0 1.3 75.2 65.6 2.5 0.0 0.1 0.1 0.0 67.6 30.0 1.4 39.5 99.1 36.8 24.3 0.0 1.8 0.0 0.8 30.8 0.1 0.1 0.1 0.0 6.8 0.0 0.0 0.0 2.8 0.0 8.5 0.0 0.0 22.1 0.0 23.5 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.9 1.5 0.8 0.1 0.0 3.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.0 22.4 0.0 46.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 12.0 3.9 2.4 3.1 4.7 2.8 3.3 2.8 2.8 2.5 3.2 0.0 0.0 0.0 0.6 5.0 0.2 0.0 1.2 0.0 0.3 2.3 0.6 2.8 0.0 11.0 0.0 0.7 0.1 0.0 0.0 0.0 4.9 1.1 20.6 2.3 0.0 0.0 1.1 0.0 0.6 33.3 0.5 0.8 0.0 0.0 3.9 3.8 1.1 0.0 0.2 0.0 0.0 0.0 7.3 7.9 66.2 0.2 7.2 3.7 0.0 3.0 0.0 0.0 0.2 0.1 0.0 100.8 0.1 0.3 0.0 0.9 0.0 0.3 52.6 19.1 63.7 1.3 0.5 0.4 3.8 1.1 0.6 0.6 0.0 0.4 MROH1 "HEATR7A, KIAA1833" ENSG00000179832 "Maestro heat like repeat family member 1" Q8NDA8 8 144148016-144261940 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 58.8" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024287, HPA044465" Approved Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA024287: , HPA044465: AB_10960985" "unprognostic (1.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (6.74e-4)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (4.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.48e-2)" "unprognostic (6.64e-2)" "unprognostic (1.92e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.61e-3)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-2)" 9.2 17.0 7.3 6.3 6.9 18.0 11.0 5.4 15.5 10.5 6.4 16.2 13.3 9.1 5.3 17.0 11.0 3.6 14.0 7.5 2.7 17.2 11.7 17.0 7.0 11.8 4.2 7.7 26.7 5.6 22.3 5.5 10.9 17.2 3.4 0.9 17.3 5.7 5.2 17.8 17.6 2.1 1.1 21.7 18.9 13.0 4.9 4.2 58.8 2.1 3.7 12.9 12.6 3.8 17.0 6.9 0.9 6.5 3.1 3.3 29.3 7.3 5.1 4.0 5.5 11.6 29.7 8.9 10.5 4.2 9.8 15.9 1.0 11.2 1.8 5.1 9.5 10.8 22.1 10.7 7.8 4.8 11.0 6.1 11.4 6.4 9.2 4.7 5.8 7.2 4.5 3.9 4.5 36.3 8.4 10.2 2.5 11.6 32.0 10.8 2.2 9.3 5.9 33.0 7.4 6.4 18.3 17.5 5.4 2.5 12.8 6.7 14.6 8.1 15.2 16.6 6.1 6.8 3.6 9.5 16.0 14.3 4.9 4.8 5.7 1.5 1.8 7.5 1.3 0.9 1.5 1.8 4.3 1.5 1.4 1.0 1.1 0.8 6.8 1.3 4.6 2.2 7.3 6.9 5.4 15.5 7.5 2.7 11.8 4.2 10.9 1.1 4.9 3.8 5.2 9.6 26.3 33.0 6.5 6.2 8.5 9.2 6.8 36.4 12.6 9.5 12.4 5.7 16.6 5.5 12.5 31.3 7.0 39.8 3.9 12.2 5.1 17.8 6.7 7.8 23.4 1.7 56.7 16.6 19.2 6.4 63.7 25.2 14.5 14.3 3.9 7.0 19.7 37.0 61.2 24.8 18.3 11.9 11.4 12.2 3.1 14.5 1.8 13.1 11.4 5.7 7.2 14.6 7.9 18.6 17.5 2.6 9.7 17.6 30.7 5.8 18.8 3.5 6.6 7.2 6.7 19.1 26.2 9.7 5.8 50.1 9.1 7.8 22.3 14.8 MRPL15 "HSPC145, L15mt, MRP-L15, MRP-L7, RPML7" ENSG00000137547 "Mitochondrial ribosomal protein L15" Q9P015 8 54135241-54148514 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 291.2;tongue: 279.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4;Syncytiotrophoblasts: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044425 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA044425: AB_10969629" "unprognostic (5.67e-3)" "unprognostic (8.89e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (9.30e-2)" "unprognostic (1.90e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-3)" "unprognostic (1.39e-1)" "unprognostic (3.39e-2)" "unprognostic (1.94e-3)" "unprognostic (1.57e-2)" "unprognostic (2.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" 42.5 34.4 33.2 36.4 34.1 25.1 49.3 37.0 50.5 32.6 38.7 70.8 58.6 28.6 27.7 48.8 35.6 29.0 169.6 33.5 38.3 83.8 89.2 26.5 42.9 36.6 35.7 30.5 29.2 83.4 18.6 49.6 35.8 27.5 67.5 63.1 41.4 29.0 291.2 38.5 50.6 45.4 33.8 27.3 38.4 14.7 38.3 38.1 35.2 279.4 57.4 64.1 26.3 33.0 164.1 118.9 98.0 122.6 76.1 110.5 125.8 128.4 93.0 173.3 150.2 134.1 197.1 253.9 170.3 112.1 164.4 161.5 206.2 165.5 190.4 109.9 109.5 165.8 62.4 168.5 114.5 92.0 168.9 103.3 167.4 159.5 165.6 74.7 366.7 89.4 208.2 80.8 251.3 156.1 262.4 177.3 206.2 313.9 60.8 169.5 63.6 136.3 210.8 147.1 56.5 83.7 66.8 204.0 167.0 97.4 195.2 96.6 129.6 95.8 111.7 139.5 151.5 94.6 128.4 207.1 88.8 137.8 153.4 40.1 93.8 27.3 50.7 123.4 63.8 100.6 64.8 68.4 141.1 76.6 59.0 56.9 3.3 54.0 115.7 88.9 79.8 85.8 33.2 34.1 37.0 50.5 33.5 38.3 36.6 35.7 35.8 33.8 38.3 33.0 28.0 25.6 14.4 9.4 33.1 23.6 40.7 114.5 19.4 28.2 25.0 37.2 120.9 55.8 50.4 36.8 29.2 160.3 17.6 38.7 248.4 103.2 18.7 34.0 34.4 34.8 18.0 31.7 10.9 70.9 155.2 32.8 23.9 39.2 25.4 37.9 26.4 59.2 106.1 25.2 12.4 52.5 75.3 44.5 22.9 4.3 24.8 37.9 33.8 7.5 56.5 37.4 20.6 11.1 6.0 97.5 34.3 22.6 35.3 33.9 66.8 127.0 32.1 58.8 13.1 32.1 70.1 14.8 34.3 37.3 34.4 198.9 19.7 91.3 78.3 41.8 MRPL34 "L34mt, MGC24974, MGC2633" ENSG00000130312 "Mitochondrial ribosomal protein L34" Q9BQ48 19 17292609-17306843 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 403.0;Proximal tubular cells: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049276 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA049276: AB_2680697" "unprognostic (1.21e-2)" "unprognostic (3.22e-2)" "unprognostic (4.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (4.27e-2)" "unprognostic (1.46e-1)" "unprognostic (4.93e-2)" "unprognostic (1.29e-1)" "unprognostic (5.45e-2)" "prognostic favorable (4.87e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.29e-6)" "unprognostic (2.44e-1)" "unprognostic (2.42e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-2)" 69.6 115.4 64.0 27.5 67.0 26.2 64.7 69.2 72.2 51.4 96.7 99.7 71.5 58.7 23.5 62.8 45.6 17.6 178.2 63.4 69.5 126.0 195.0 47.1 28.6 64.3 64.1 40.9 69.5 91.8 74.1 20.3 64.6 55.3 29.8 31.6 65.3 40.2 210.5 60.6 75.8 18.3 64.1 55.8 87.7 93.6 70.7 38.0 61.5 139.6 21.8 64.0 50.6 66.0 91.9 55.3 35.4 45.4 88.2 48.7 132.1 45.4 47.7 36.6 44.8 53.6 64.2 115.2 126.7 25.2 50.7 73.6 57.1 53.5 25.9 171.3 198.5 81.4 87.2 119.2 78.7 89.2 103.9 56.6 71.2 38.0 52.1 38.9 57.8 95.5 119.6 136.4 35.7 86.7 113.4 187.4 97.6 147.2 293.8 97.9 52.0 160.9 107.9 68.6 84.1 136.7 42.6 67.2 105.9 37.0 58.7 74.3 49.0 52.7 32.8 151.6 87.4 186.5 305.3 129.0 65.4 161.7 49.1 169.6 162.3 159.5 172.4 177.0 192.5 204.0 203.5 177.3 178.1 211.0 197.5 172.2 52.3 141.7 107.0 233.6 210.8 276.7 64.0 67.0 69.2 72.2 63.4 69.5 64.3 64.1 64.6 64.1 70.7 66.0 64.4 35.3 41.4 13.7 51.7 60.7 33.0 128.5 74.0 50.2 81.7 108.2 153.4 91.5 64.6 82.8 20.9 118.5 94.1 138.9 403.0 88.5 57.6 48.1 46.7 54.2 68.3 45.5 16.1 68.8 112.1 55.6 60.1 45.4 39.3 37.1 59.6 290.3 172.4 42.1 16.7 125.4 134.3 70.1 55.9 31.9 82.0 61.4 81.8 6.5 90.0 45.0 97.9 6.0 12.8 64.7 99.1 91.7 80.3 45.7 219.5 414.8 42.3 49.7 72.3 48.1 69.7 233.1 14.9 93.2 72.0 78.3 62.0 109.5 130.6 36.7 MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Proximal tubular cells: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cell Junctions" "HPA050166: AB_2681039, HPA076046: " "unprognostic (1.42e-1)" "unprognostic (6.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-2)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (4.64e-3)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "prognostic favorable (2.09e-6)" "unprognostic (7.73e-2)" "unprognostic (9.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.63e-1)" 25.1 51.5 20.3 12.9 21.7 11.3 22.7 23.7 25.4 14.6 22.0 24.2 20.0 17.1 18.2 26.4 17.1 13.0 76.1 20.8 23.6 34.7 70.9 12.7 20.9 23.1 22.1 17.2 16.2 24.6 16.2 19.6 23.6 14.9 23.6 16.8 17.1 15.2 73.3 17.9 19.7 18.4 21.7 19.1 24.8 28.1 22.7 18.9 17.2 84.6 20.3 20.7 16.2 22.6 27.8 87.2 27.2 29.8 38.0 28.6 51.5 38.6 35.5 56.9 50.4 108.6 59.3 64.9 38.6 34.9 51.0 65.9 107.4 47.4 44.8 26.3 86.4 53.6 61.5 114.3 24.6 54.2 40.4 32.7 56.6 42.8 28.7 29.0 50.2 63.2 60.7 26.6 42.7 59.6 44.2 68.4 43.5 50.5 52.9 51.9 37.9 49.2 44.5 88.2 42.1 26.5 36.6 57.7 81.8 44.6 64.8 65.7 31.3 44.0 41.9 23.3 56.4 24.2 55.7 53.0 48.5 58.1 34.2 27.1 45.5 33.7 60.0 60.5 69.6 78.8 63.3 58.7 58.7 69.5 69.5 61.6 7.9 62.9 45.0 50.5 68.0 61.5 20.3 21.7 23.7 25.4 20.8 23.6 23.1 22.1 23.6 21.7 22.7 22.6 18.9 0.0 10.3 5.2 21.0 13.8 22.4 59.8 9.6 21.2 17.3 21.3 70.4 37.1 32.3 36.8 27.1 94.3 10.7 20.4 119.3 35.0 67.1 20.0 16.6 18.4 28.3 17.7 4.2 38.0 42.1 19.2 19.9 19.5 22.2 25.8 17.2 105.0 35.6 15.2 5.9 20.6 44.7 13.4 5.5 16.3 14.3 10.8 7.2 3.7 42.1 25.1 20.6 4.5 6.1 31.7 18.4 18.8 17.3 21.9 32.1 133.6 26.2 28.4 26.3 19.5 25.5 55.3 27.4 27.1 23.3 80.7 18.5 66.9 36.1 29.4 MRPS11 "FLJ22512, FLJ23406, HCC-2" ENSG00000181991 "Mitochondrial ribosomal protein S11" P82912 15 88467453-88480776 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043752, HPA050345" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043752: AB_2678653, HPA050345: AB_2681100" "unprognostic (2.66e-1)" "prognostic favorable (3.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (3.21e-1)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "unprognostic (6.45e-2)" "prognostic favorable (4.75e-4)" "unprognostic (8.31e-2)" "unprognostic (3.37e-1)" "unprognostic (1.83e-1)" "unprognostic (9.44e-2)" "unprognostic (7.26e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" 9.4 16.9 12.0 4.0 12.1 2.8 8.6 12.8 18.3 5.3 11.4 9.3 7.9 5.3 3.8 10.9 4.8 4.5 26.1 12.5 12.1 14.0 20.5 5.2 5.6 12.7 12.3 3.5 10.5 3.8 7.6 2.3 12.9 7.4 3.5 2.5 6.0 3.4 24.7 7.2 7.4 4.3 11.7 8.0 9.6 9.0 12.7 5.1 9.6 15.0 4.4 8.4 5.6 12.1 10.5 41.1 6.1 10.4 13.8 6.6 16.1 8.3 14.6 10.7 11.5 28.9 16.0 9.7 17.0 7.1 11.3 14.8 17.9 11.5 5.5 12.8 43.8 13.2 23.1 32.0 16.5 4.5 8.3 13.4 11.1 9.2 9.2 5.8 14.3 12.3 9.6 4.3 18.1 45.1 9.3 19.0 16.3 13.4 43.8 19.0 11.6 23.0 15.5 28.4 19.3 9.6 8.6 21.6 33.6 5.3 19.8 24.7 6.8 15.2 16.8 9.9 12.5 8.5 16.5 11.7 18.3 11.2 16.3 31.1 25.1 19.3 15.1 27.6 17.6 27.5 17.2 17.8 29.5 18.2 18.1 17.6 9.5 30.1 17.8 31.9 35.1 26.0 12.0 12.1 12.8 18.3 12.5 12.1 12.7 12.3 12.9 11.7 12.7 12.1 42.1 6.4 20.4 10.4 30.4 22.8 27.5 69.2 31.9 36.9 38.1 47.2 6.3 35.8 39.6 46.0 47.9 91.0 34.6 85.5 135.0 63.9 30.2 27.1 37.8 34.2 24.7 40.6 14.0 66.8 89.7 32.7 25.0 32.5 33.6 40.4 44.6 92.6 90.5 26.9 15.0 60.3 50.8 33.1 24.5 34.2 33.2 31.0 32.0 8.4 65.0 44.4 72.1 16.6 16.8 67.0 70.7 42.5 36.5 32.2 90.8 145.3 29.7 45.1 19.7 29.7 51.8 90.3 42.0 49.1 28.3 89.6 32.3 96.0 64.6 34.5 MRPS15 FLJ11564 ENSG00000116898 "Mitochondrial ribosomal protein S15" P82914 1 36455718-36464384 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 287.3" "Cell type enhanced" "Detected in all" "Early spermatids: 776.7;Late spermatids: 2209.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028100, HPA028134, HPA067137" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA028100: AB_10600216, HPA028134: AB_10600890, HPA067137: AB_2685787" "unprognostic (2.05e-2)" "unprognostic (6.98e-2)" "unprognostic (7.57e-2)" "unprognostic (4.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.20e-2)" "unprognostic (3.28e-2)" "prognostic favorable (7.83e-4)" "unprognostic (8.48e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (2.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.94e-2)" "unprognostic (1.39e-1)" 77.3 68.9 54.1 37.4 55.7 81.7 62.4 58.5 70.4 38.8 61.8 63.7 41.1 42.5 62.6 70.9 37.1 30.2 133.8 54.8 59.8 82.0 122.1 47.4 45.4 57.9 56.8 33.2 63.2 77.0 46.3 45.0 58.3 45.1 50.7 21.0 58.1 37.8 287.3 53.0 41.6 40.0 54.4 41.3 68.7 151.2 58.1 44.1 40.0 196.9 47.9 54.2 43.0 56.0 162.3 88.7 94.4 115.8 91.9 132.6 233.9 88.3 126.1 214.3 195.7 157.9 169.3 148.8 140.0 117.3 128.1 138.9 139.5 223.3 192.3 97.4 177.0 152.5 104.1 175.2 171.6 190.2 103.2 123.1 196.1 191.2 153.7 82.5 178.0 109.5 168.1 114.0 134.5 112.2 184.7 203.8 169.8 137.2 154.2 140.4 165.6 218.6 193.0 135.1 139.4 77.0 122.2 153.9 236.0 139.7 95.1 129.0 84.3 119.7 126.8 149.0 189.4 113.2 169.1 211.3 136.1 128.1 170.8 18.7 78.9 22.3 61.8 89.7 77.3 72.5 70.3 71.2 122.0 73.5 65.6 64.4 5.3 64.5 61.2 83.6 87.8 90.7 54.1 55.7 58.5 70.4 54.8 59.8 57.9 56.8 58.3 54.4 58.1 56.0 50.6 38.5 52.0 10.1 57.2 65.4 70.3 119.6 55.8 23.2 85.6 79.9 136.7 65.8 74.7 71.7 14.6 245.9 49.2 84.8 322.9 132.8 776.7 53.2 58.6 62.6 66.0 118.2 8.7 162.4 260.3 61.7 69.3 75.4 42.5 71.1 62.4 140.6 153.8 13.5 8.7 97.7 85.5 81.1 68.9 2209.2 62.7 75.7 56.9 4.7 86.7 31.3 56.7 5.5 7.2 143.1 64.2 74.4 108.4 128.8 118.3 361.6 50.3 23.5 65.7 56.3 103.2 502.4 76.0 107.0 80.4 281.6 59.0 113.1 127.2 118.3 MRPS36 "DC47, MRP-S36" ENSG00000134056 "Mitochondrial ribosomal protein S36" P82909 5 69217760-69230158 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 546.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035802, HPA056795" Supported Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA035802: AB_10600933, HPA056795: AB_2683237" "unprognostic (1.19e-1)" "unprognostic (6.78e-3)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (2.96e-3)" "unprognostic (1.99e-1)" "unprognostic (7.49e-2)" "unprognostic (1.49e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (3.90e-1)" "prognostic favorable (5.02e-6)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.37e-2)" "unprognostic (4.84e-3)" 20.3 18.4 20.1 12.7 20.3 21.0 16.5 21.3 26.3 12.7 20.2 23.6 24.1 12.8 15.4 20.3 12.7 10.4 67.3 20.1 21.5 49.2 38.0 14.7 15.1 20.3 20.6 12.4 14.7 31.3 9.8 13.0 20.6 14.4 24.3 18.9 13.7 12.1 47.0 12.6 24.0 12.4 20.3 11.6 21.8 8.6 20.8 15.7 17.2 67.7 16.7 16.6 14.0 20.5 29.2 27.6 19.1 26.4 32.8 33.1 50.3 25.6 24.5 32.1 39.4 38.6 31.8 31.2 51.9 21.8 71.8 29.3 32.1 38.8 31.7 36.8 33.6 21.3 31.4 43.4 38.7 22.9 27.9 34.6 27.3 30.7 14.5 33.4 24.0 31.9 25.7 22.9 28.7 31.8 35.3 34.9 14.2 26.8 31.9 20.6 33.2 47.9 56.4 32.5 26.6 25.9 26.2 37.9 46.3 30.9 29.0 32.9 17.6 14.3 24.5 32.0 44.5 23.9 41.9 41.6 25.0 42.1 19.1 36.3 22.1 29.3 22.7 32.0 25.4 31.1 25.7 25.8 27.9 25.0 22.8 24.7 25.1 26.5 30.2 27.4 40.3 17.7 20.1 20.3 21.3 26.3 20.1 21.5 20.3 20.6 20.6 20.3 20.8 20.5 64.5 115.4 83.6 16.3 76.5 81.4 101.1 204.0 83.1 26.3 72.4 109.3 333.1 97.2 104.3 88.3 14.6 126.8 67.5 220.5 401.1 118.4 127.7 123.3 79.5 57.2 92.8 97.2 20.4 139.5 192.4 68.6 67.2 113.0 56.4 41.4 52.1 216.1 127.1 28.6 21.4 162.8 120.1 102.4 67.5 45.2 64.7 72.9 106.7 10.3 142.0 61.8 56.7 10.6 17.1 137.1 190.1 69.2 60.5 100.5 256.6 546.3 86.4 45.9 72.3 78.7 92.3 66.1 37.9 86.9 76.9 123.3 64.2 76.9 168.1 114.6 MS4A1 "B1, Bp35, CD20, MS4A2" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 673.3" "Cell type enriched" "Detected in some" 35 "B-cells: 970.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 625.4;naive B-cell: 627.0" "Lineage enriched" "Detected in many" 96 "B-cells: 627.0" "Group enriched" "Detected in some" 26 "Daudi: 731.3;U-698: 364.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "CAB000015: AB_2282030, HPA014341: AB_1846265, HPA014391: AB_1846264" "prognostic favorable (4.34e-5)" "unprognostic (4.45e-4)" "unprognostic (1.19e-4)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (5.53e-7)" "unprognostic (2.46e-3)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.89e-4)" "unprognostic (6.96e-2)" "unprognostic (2.84e-2)" "unprognostic (3.96e-5)" "unprognostic (2.23e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" 3.6 0.4 0.0 149.7 0.0 19.1 0.8 0.0 0.1 0.5 0.1 9.0 3.0 2.2 1.0 4.2 0.5 8.4 1.8 0.0 0.1 3.4 2.1 4.0 500.4 0.2 0.0 0.3 0.2 7.3 0.3 0.9 0.1 5.1 10.6 0.0 8.9 0.3 0.8 0.1 123.5 1.2 0.1 253.8 18.4 1.2 0.1 50.6 6.7 0.1 673.3 16.3 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 731.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.5 0.2 0.0 0.1 0.0 364.1 0.0 0.2 0.0 0.8 0.5 0.3 2.4 0.1 3.7 625.4 2.8 5.5 0.5 627.0 0.5 2.1 2.0 6.5 0.6 0.5 0.8 32.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 3.8 0.0 970.5 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 4.5 0.7 0.1 0.3 0.0 7.0 0.0 0.0 0.1 1.8 2.0 0.1 2.5 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.0 0.6 0.3 2.0 0.0 4.6 7.2 0.0 2.5 0.0 2.1 0.0 0.0 0.0 0.3 0.0 9.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.8 0.1 0.0 27.3 0.7 0.2 0.0 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 213.3 83.3 66.6 259.8 71.4 269.8 144.6 80.0 70.9 113.9 79.6 116.0 43.9 155.8 45.0 87.9 110.0 123.1 130.2 64.8 95.9 139.7 91.8 281.5 207.5 101.9 79.6 91.9 41.0 39.2 48.2 150.6 98.8 72.5 78.4 24.0 76.0 126.6 56.2 100.7 96.6 251.6 91.8 200.0 78.4 21.9 87.3 177.0 152.5 75.7 242.2 154.8 98.0 95.5 298.3 223.2 214.0 177.9 250.6 328.9 1.9 733.9 472.2 397.3 305.5 0.6 50.9 247.7 638.8 654.4 210.3 199.4 228.5 523.4 514.1 461.7 63.0 687.5 355.0 0.6 236.0 845.3 1063.8 248.1 110.7 733.1 641.5 384.2 892.3 338.5 339.5 747.1 638.4 0.6 503.0 631.0 266.1 0.3 418.9 259.8 384.0 189.0 426.5 0.2 1.7 0.8 590.6 4.4 231.5 239.7 2.7 453.8 1426.9 449.5 285.3 613.2 494.6 268.6 438.4 262.5 328.9 1053.3 513.0 219.9 312.4 194.0 214.8 359.3 160.4 91.9 116.9 170.6 225.3 76.9 78.3 121.9 334.3 177.5 460.3 31.9 97.0 673.8 66.6 71.4 80.0 70.9 64.8 95.9 101.9 79.6 98.8 91.8 87.3 95.5 243.4 179.5 163.0 19.9 140.8 205.5 62.2 56.5 38.7 0.7 27.9 30.9 27.5 11.5 45.4 68.0 4.2 6.0 227.3 7.5 29.4 177.3 1.4 35.7 64.9 256.2 0.0 71.9 2.2 170.0 16.0 85.7 16.3 62.9 164.6 22.6 100.3 51.2 167.2 5.0 3.8 3.2 2.0 255.3 206.2 5.3 73.7 251.9 69.4 67.5 291.9 43.6 337.8 7.1 14.7 327.7 3.3 109.4 105.7 102.2 0.0 113.6 25.6 2.4 72.3 85.0 131.0 1.9 3.6 24.3 149.5 4.2 206.9 24.4 2.2 54.0 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MSRB1 "SelR, SelX, SepR, SEPX1" ENSG00000198736 "Methionine sulfoxide reductase B1" Q9NZV6 16 1938229-1943293 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 275.6;monocytes: 178.7;Proximal tubular cells: 496.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1414.9;neutrophil: 3051.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 3051.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008650, HPA043463, HPA069557" Enhanced Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "CAB008650: AB_1619225, HPA043463: AB_2678489, HPA069557: AB_2686153" "unprognostic (3.93e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.88e-2)" "unprognostic (4.90e-2)" "unprognostic (5.29e-2)" "unprognostic (3.60e-1)" "unprognostic (4.27e-2)" "unprognostic (8.46e-2)" "unprognostic (4.92e-2)" "unprognostic (7.31e-2)" "unprognostic (4.59e-3)" 28.1 15.1 26.2 31.8 27.3 96.3 21.3 27.8 28.4 17.5 25.8 36.7 29.4 29.5 11.2 45.3 33.5 23.2 47.3 25.6 26.8 80.3 234.2 30.4 17.7 29.3 28.0 16.4 149.6 14.8 14.5 13.2 27.1 32.0 17.4 2.7 16.5 29.2 76.0 31.1 27.5 36.8 27.5 67.0 33.3 17.7 28.5 13.7 12.5 93.6 12.2 40.8 20.1 27.1 23.6 59.1 21.3 50.4 39.9 17.0 36.4 27.8 36.0 41.2 35.6 96.2 25.5 22.7 90.6 33.5 36.0 37.9 36.3 25.2 12.8 127.7 41.1 17.5 20.5 154.9 36.1 49.3 40.3 32.0 21.9 29.6 6.0 12.9 41.9 28.8 28.2 12.3 22.3 131.2 28.2 82.7 29.2 42.7 33.5 40.3 29.3 106.0 66.0 37.2 20.5 26.9 32.3 35.6 17.3 13.9 38.7 87.9 24.8 12.3 33.7 24.3 16.7 32.0 53.4 42.4 12.5 47.4 22.0 493.5 412.0 1414.9 31.9 194.8 32.2 28.0 26.5 26.7 171.2 28.3 20.5 22.7 3051.8 42.2 182.9 73.2 45.9 226.7 26.2 27.3 27.8 28.4 25.6 26.8 29.3 28.0 27.1 27.5 28.5 27.1 24.9 9.6 13.4 3.9 10.0 6.5 9.1 21.5 8.0 6.5 27.9 21.3 36.1 32.9 14.9 33.1 4.2 33.3 12.3 69.1 93.9 65.9 5.9 23.9 13.4 15.4 60.3 21.5 0.8 111.2 121.4 13.7 11.7 17.0 4.5 12.2 20.7 275.6 63.5 8.4 1.2 38.6 34.6 59.2 21.2 13.9 9.3 37.9 16.0 2.8 178.7 22.5 25.7 1.5 2.9 66.0 62.8 23.0 13.0 16.3 97.3 496.8 37.9 4.2 0.0 8.1 22.8 28.9 8.7 11.1 9.5 38.6 10.6 14.8 33.5 21.9 MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 2801.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.6" "Lineage enhanced" "Detected in many" "granulocytes: 41.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 126.1;hTERT-RPE1: 110.6;U-937: 106.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Enhanced "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (2.17e-4)" 44.9 10.7 12.9 20.9 13.6 21.2 26.3 12.5 12.8 29.5 18.8 108.0 11.9 85.8 20.1 63.0 41.4 33.2 90.8 11.9 18.3 10.1 3.8 30.6 5.7 15.9 15.2 16.9 5.8 3.2 6.8 25.2 13.8 52.7 27.8 12.5 10.8 103.0 104.0 9.7 25.6 123.9 14.6 13.6 36.2 5.8 18.2 4.1 14.5 69.2 3.9 60.9 23.7 11.8 8.8 19.2 16.4 75.9 71.6 63.0 0.5 87.0 92.9 33.2 19.8 0.7 1.0 0.0 18.3 126.1 10.5 1.9 7.7 22.1 30.0 0.2 15.9 0.0 16.7 0.9 46.6 47.1 0.3 33.4 11.9 28.1 39.0 110.6 68.2 0.1 0.3 0.3 76.8 2.9 0.0 11.0 5.4 0.2 10.4 0.2 22.0 0.5 7.5 1.0 0.4 7.9 30.0 1.8 21.9 16.8 14.1 44.5 78.9 42.3 22.8 19.5 34.2 8.0 6.7 0.2 11.5 106.7 26.9 15.0 0.6 41.6 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 6.8 8.3 0.4 10.8 0.1 1.4 12.9 13.6 12.5 12.8 11.9 18.3 15.9 15.2 13.8 14.6 18.2 11.8 55.3 12.8 3.4 76.7 0.8 6.4 16.4 11.4 4.0 22.7 2.2 45.3 2801.7 4.3 1.2 3.7 0.0 0.4 8.3 0.0 0.0 9.3 5.7 0.9 16.7 154.2 0.0 17.4 37.1 1.0 0.4 108.8 1.1 0.4 2.5 7.4 28.2 0.2 0.5 21.9 56.6 0.0 0.0 0.0 13.7 2.2 12.5 4.0 10.6 62.8 1.6 44.4 2.1 37.7 1.4 1.6 0.0 116.6 0.3 14.8 0.0 0.4 6.8 10.6 105.2 37.7 218.7 4.2 4.7 0.8 4.5 0.7 2.4 10.3 0.0 2.9 MSX2 "CRS2, FPP, HOX8, MSH, PFM, PFM1" ENSG00000120149 "Msh homeobox 2" P35548 5 174724582-174730896 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 25.8;placenta: 33.6;urinary bladder: 17.5" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 162.6;Endometrial ciliated cells: 65.7;Glandular and luminal cells: 62.2;Syncytiotrophoblasts: 233.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 18.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 322.0" "Region enriched" "Detected in some" 5 "cerebellum: 6.2" "Low region specificity" "Detected in many" HPA005652 Uncertain Supported "Nuclear speckles" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" "HPA005652: AB_1079418" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-4)" "unprognostic (7.64e-3)" "unprognostic (5.06e-2)" "unprognostic (2.12e-6)" "unprognostic (1.43e-2)" 2.1 0.3 0.7 0.5 1.0 0.0 8.1 4.3 1.1 2.7 1.1 0.9 0.3 6.8 0.0 0.6 0.9 0.9 1.6 1.2 1.4 0.3 0.0 0.8 0.1 7.8 1.3 0.2 0.4 25.8 0.3 33.6 4.1 2.5 0.1 0.0 0.8 0.8 1.9 6.9 0.8 1.4 5.4 0.8 2.8 5.6 1.3 0.1 0.7 1.8 0.1 17.5 1.8 5.4 0.4 4.0 1.1 3.2 0.0 0.0 322.0 2.2 3.6 0.7 0.1 56.6 23.0 0.0 8.6 0.2 19.6 6.2 17.6 6.4 0.2 0.0 10.7 0.0 1.4 0.0 2.4 0.0 3.0 3.7 4.5 3.1 3.5 0.0 0.0 0.0 0.0 0.0 5.0 27.7 0.0 0.4 2.5 38.3 8.5 0.0 8.8 0.1 4.0 35.3 0.0 2.5 0.0 43.0 2.9 69.6 25.7 0.2 0.0 1.1 5.5 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 4.3 1.1 1.2 1.4 7.8 1.3 4.1 5.4 1.3 5.4 1.5 0.0 0.0 2.3 0.0 9.6 2.4 0.1 3.4 0.2 15.8 18.9 1.7 0.0 0.1 0.0 0.0 162.6 0.2 0.3 0.0 0.6 0.2 65.7 4.9 0.7 0.0 0.0 0.0 0.0 13.9 5.3 5.1 62.2 4.5 0.1 0.4 0.0 11.3 0.0 0.0 1.9 0.0 0.6 2.9 0.6 0.0 1.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.3 1.9 0.1 0.1 0.0 0.0 8.9 4.8 1.4 4.5 2.0 11.4 233.8 1.0 0.6 1.2 9.8 MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 222644.8;heart muscle: 255389.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107039.5;Hepatocytes: 59794.3;Proximal enterocytes: 98329.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 54167.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB016241: AB_2229888, HPA069328: AB_2686122" "unprognostic (4.39e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "prognostic favorable (2.29e-4)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (1.20e-2)" "unprognostic (6.60e-2)" "unprognostic (2.83e-2)" "unprognostic (5.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-2)" 22006.8 46968.9 171347.0 8727.7 151652.8 11321.8 17952.5 132201.9 222644.8 10440.9 179120.2 42606.0 27505.7 11582.9 14226.0 20791.8 10700.5 11452.7 255389.3 151507.6 137459.2 63061.8 96575.5 12744.7 9111.4 176794.8 152802.2 8124.5 19467.4 41236.2 7420.2 10527.8 168465.9 12427.0 28389.7 12503.0 23260.1 17753.2 147209.5 26849.0 35366.3 13146.2 138626.1 16284.7 44852.9 10932.5 176888.2 7461.1 14056.3 184587.7 8381.2 17415.3 10559.7 131378.4 5837.6 8554.3 11384.1 12431.0 25510.2 11563.1 12037.2 12867.2 4284.9 3189.4 5257.4 10383.6 18320.5 15138.9 6040.7 9857.6 3118.2 21430.9 1326.6 11407.4 4515.1 7226.0 8040.6 9130.6 54167.9 19725.4 3521.2 5336.1 11055.5 13603.9 11589.8 3149.9 6917.5 14668.4 3902.1 8485.5 5916.3 10551.1 9525.6 14037.0 4378.4 23591.9 2905.0 7814.2 6900.5 5664.0 3401.6 9177.9 15910.6 15016.1 5414.7 7189.1 4466.7 17018.9 8305.7 13626.1 9809.7 17703.3 15637.8 12617.8 8438.9 12565.9 6642.1 4951.2 5072.9 3542.6 6235.7 13711.8 6294.4 5305.8 9759.2 3824.6 3085.1 4907.9 3420.5 5374.6 3047.3 3425.6 3444.6 5567.3 3080.8 3911.2 1900.4 3759.1 5775.1 4847.5 2947.7 3929.0 171347.0 151652.8 132201.9 222644.8 151507.6 137459.2 176794.8 152802.2 168465.9 138626.1 176888.2 131378.4 3924.0 2900.6 3897.1 0.0 13282.9 9769.7 9713.9 22625.0 20857.7 0.0 12033.2 11841.6 107039.5 30777.5 16135.4 19596.3 0.0 0.0 9288.4 40726.1 4255.4 7191.4 1555.3 13044.7 9033.9 7847.9 7514.7 45610.3 0.0 5089.4 0.0 6305.3 19235.7 25645.6 3832.6 20400.0 25951.4 59794.3 0.0 0.0 0.0 24302.1 19071.0 45533.4 7744.0 7398.4 11696.4 12124.7 6894.2 0.0 15180.0 0.0 8901.3 0.0 0.0 6410.5 23865.9 8490.1 13829.3 9441.3 98329.8 33652.6 10474.0 0.0 13614.6 11019.8 9403.5 12096.5 14338.7 27110.9 11475.1 0.0 11502.4 15179.6 27138.6 21770.7 MT-CO2 "CO2, COX2, MTCO2" ENSG00000198712 "Mitochondrially encoded cytochrome c oxidase II" P00403 MT 7586-8269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 164780.5;heart muscle: 210840.8" "Cell type enriched" "Detected in many" 13 "Cardiomyocytes: 709929.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 73985.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016243, HPA051505, HPA054758" Enhanced NA NA 240000 "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016243: AB_2066366, HPA051505: AB_2681511, HPA054758: AB_2682595" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (2.77e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (2.72e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.25e-1)" "unprognostic (9.30e-2)" "unprognostic (3.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.50e-2)" "unprognostic (3.72e-3)" 27287.7 50118.4 114427.0 5960.9 114629.6 9211.1 23112.5 102567.5 164780.5 8637.9 123709.0 47542.8 18239.3 10045.0 10813.1 24529.5 11015.1 5914.4 210840.8 108795.0 110116.5 112074.1 105449.6 14032.6 6314.3 129884.9 115346.3 7950.6 24515.9 29782.0 16861.9 10397.8 125082.8 25688.4 24989.1 8983.3 21379.6 12907.0 93258.6 22997.0 36121.9 9693.6 102620.8 18194.3 45409.4 14516.5 123032.8 6034.4 16877.7 109930.2 7889.2 21068.8 13184.5 102646.5 6276.2 9796.4 12777.6 12396.3 25548.5 9745.3 9393.2 7927.6 6429.8 4420.4 6584.3 10616.0 13681.5 12924.1 6467.6 11751.8 4522.1 23074.6 1724.1 16319.1 5925.8 10089.3 8726.0 9297.7 73985.8 20756.8 5543.0 7919.2 9987.0 14433.8 23568.7 2276.3 8072.8 14337.8 4979.3 12668.7 8862.9 12216.0 12212.6 13490.3 5804.8 22519.7 3353.4 12256.7 6160.6 5998.2 3899.6 10866.7 17578.2 17096.2 4758.2 7830.6 6527.3 15842.4 11881.3 18742.2 11084.6 31596.4 12345.0 10576.0 9043.3 10116.0 5740.6 6151.2 6563.0 7590.8 5638.0 15586.1 7129.7 20953.0 13541.7 15753.7 5586.8 8887.6 6782.0 11844.8 6189.5 6338.9 6316.7 10947.0 6386.1 7947.1 5329.9 6846.5 10055.3 8426.1 5367.4 7670.7 114427.0 114629.6 102567.5 164780.5 108795.0 110116.5 129884.9 115346.3 125082.8 102620.8 123032.8 102646.5 4337.7 1445.5 1999.8 0.0 11825.3 6754.0 8961.4 22171.6 22140.9 0.0 11994.6 16742.4 709929.9 18464.2 10323.3 18597.6 0.0 0.0 7569.1 29582.2 3709.5 3684.4 1119.7 12108.5 6979.9 16215.0 6396.9 27238.9 0.0 4873.7 0.0 10942.5 19089.4 20683.3 2144.6 17185.5 15141.7 53416.5 0.0 0.0 0.0 17158.1 14290.0 26774.7 4814.0 5284.9 7663.3 9292.7 5140.4 0.0 7967.0 0.0 6828.1 0.0 0.0 4709.1 15133.6 5123.0 14109.6 5949.4 40280.5 22569.2 7617.1 0.0 7060.4 9361.8 14171.2 7120.5 8965.1 26952.2 6702.8 0.0 8863.0 13639.8 19371.4 14261.8 MT-ND5 "MTND5, NAD5, ND5" ENSG00000198786 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5" P03915 MT 12337-14148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 25147.7;heart muscle: 26116.9;skeletal muscle: 25697.4" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 35040.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 10198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.87e-1)" "unprognostic (3.18e-2)" "unprognostic (3.00e-1)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-3)" "unprognostic (5.09e-3)" "unprognostic (1.06e-2)" "unprognostic (3.01e-1)" "unprognostic (3.29e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.31e-5)" "unprognostic (9.93e-3)" "unprognostic (8.75e-2)" "unprognostic (1.26e-2)" "unprognostic (3.68e-2)" 5288.6 4777.7 18907.8 1742.2 18307.4 1525.5 2456.7 14400.2 21432.3 1614.3 22368.1 4280.6 4135.2 1972.7 2508.1 2717.8 3030.2 2040.5 26116.9 16370.1 20521.2 8014.5 10041.3 2683.6 1180.6 25147.7 20794.2 1886.3 2631.6 4813.1 1528.8 1691.5 23065.0 2812.7 2879.0 3264.8 2819.2 2163.8 25697.4 6657.3 4780.7 2643.7 13881.7 2014.4 6673.9 1678.5 21024.6 794.7 2059.1 19444.2 1541.4 3557.5 1537.7 13870.1 1615.8 1671.5 1998.7 1937.9 5903.9 1530.3 1075.8 3208.3 492.5 355.1 583.1 2472.6 2051.0 3865.3 1590.5 1510.4 397.3 3350.6 191.2 1685.7 583.4 2182.3 1281.4 2840.4 10198.2 4239.2 678.8 2010.7 2824.3 2305.4 1315.5 401.6 951.8 1933.5 725.2 1233.3 1056.8 1794.8 1216.3 3046.1 757.3 2453.4 397.5 910.2 903.0 1432.9 938.2 1668.7 2083.2 3132.2 595.0 904.1 1496.1 2636.3 894.4 3001.9 1927.1 2979.2 5094.9 2013.2 1403.2 2409.7 1271.9 678.8 1246.0 1066.9 1077.4 1780.4 897.7 2851.8 1521.7 874.2 771.4 980.3 922.8 979.1 753.9 839.2 746.5 1096.6 729.2 869.0 446.2 785.1 1039.5 890.3 628.6 492.0 18907.8 18307.4 14400.2 21432.3 16370.1 20521.2 25147.7 20794.2 23065.0 13881.7 21024.6 13870.1 773.3 628.2 594.2 0.0 1707.9 895.1 1050.1 1005.5 3261.6 0.0 1003.4 1025.1 35040.8 2566.4 934.5 1156.8 0.0 0.0 977.0 3181.2 283.7 804.1 109.5 3130.4 2025.6 1614.3 782.9 3776.6 0.0 936.6 0.0 1437.2 3609.6 5212.8 862.1 2987.5 2623.3 6597.7 0.0 0.0 0.0 1776.8 583.9 3664.2 661.9 528.9 1057.5 1364.5 608.3 0.0 1303.9 0.0 756.0 0.0 0.0 1327.8 2211.7 848.6 2674.2 753.3 4484.5 2410.8 1282.0 0.0 696.8 1941.5 1558.6 652.2 521.9 3002.4 973.6 0.0 1527.8 1560.9 1650.5 1506.6 MT1A "MT1, MT1S" ENSG00000205362 "Metallothionein 1A" P04731 16 56638666-56640087 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 488.0;liver: 430.8" "Group enriched" "Detected in many" 6 "Adipocytes: 797.9;Fibroblasts: 244.1;Hepatocytes: 343.8;Skeletal myocytes: 561.9;Smooth muscle cells: 889.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 33.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 18.4;ASC TERT1: 27.9;HHSteC: 19.7;HMC-1: 29.5;hTEC/SVTERT24-B: 80.2;NTERA-2: 40.1" "Low region specificity" "Detected in single" "CAB002161, CAB013056" Approved NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "CAB002161: AB_563878, CAB013056: " "unprognostic (1.36e-1)" "unprognostic (4.91e-3)" "unprognostic (1.22e-1)" "unprognostic (3.30e-1)" "unprognostic (1.26e-3)" "unprognostic (9.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (6.67e-3)" "unprognostic (3.10e-2)" "unprognostic (1.86e-1)" "unprognostic (9.43e-2)" "unprognostic (1.35e-2)" 488.0 64.3 9.8 10.8 12.3 0.0 208.1 9.8 14.1 62.0 8.2 28.9 7.7 13.6 1.3 33.4 68.7 30.2 63.3 9.3 10.7 136.8 430.8 115.2 0.6 10.6 10.8 19.8 90.3 2.1 25.9 0.7 11.7 33.1 13.1 4.4 18.9 2.9 100.0 26.1 23.4 16.9 11.5 3.4 42.9 8.4 10.8 6.1 67.7 6.1 0.7 34.0 22.6 9.7 0.0 6.2 0.0 0.1 18.4 27.9 0.4 1.9 7.9 1.2 1.5 2.3 4.8 0.0 2.4 1.1 0.0 0.5 0.0 0.4 2.9 0.0 0.0 0.0 2.5 9.9 19.7 0.2 29.5 8.2 0.0 80.2 0.0 0.0 7.7 0.0 0.7 0.0 5.5 0.0 0.0 0.1 40.1 0.0 0.0 0.0 0.0 3.6 0.5 0.0 0.3 0.1 0.0 0.3 0.0 0.9 0.0 0.3 6.3 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 9.8 12.3 9.8 14.1 9.3 10.7 10.6 10.8 11.7 11.5 10.8 9.7 797.9 9.6 1.7 0.7 1.8 27.4 11.3 1.9 5.7 0.0 11.7 15.4 5.4 8.6 5.1 0.0 0.0 1.1 1.0 11.1 13.7 2.7 0.1 11.9 6.9 63.2 3.6 29.5 0.0 1.8 12.8 244.1 5.1 23.8 3.8 0.3 15.7 343.8 0.3 0.0 0.0 32.3 0.0 10.4 39.6 0.7 55.0 12.4 33.8 0.0 0.0 0.0 0.0 0.0 0.0 3.0 18.6 12.8 1.2 27.9 86.5 16.1 3.0 0.0 26.3 561.9 889.5 0.0 0.3 2.1 19.5 0.5 6.6 0.4 34.7 13.7 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 569.2;Proximal tubular cells: 508.1;Spermatocytes: 435.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038390: AB_10669723" "unprognostic (4.94e-2)" "unprognostic (3.29e-1)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (4.27e-1)" "unprognostic (7.63e-3)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.12e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" 28.8 40.3 13.2 14.1 14.1 12.6 25.3 14.3 15.7 20.5 12.7 41.7 38.9 26.8 19.4 50.3 18.9 11.9 41.0 13.8 15.1 57.3 115.3 20.0 14.7 13.3 14.0 13.6 22.6 21.2 18.5 9.9 13.7 18.3 32.7 16.2 29.8 11.9 81.8 28.7 37.6 21.4 12.8 19.6 22.6 69.8 14.7 14.6 21.6 47.5 23.0 23.2 26.1 14.9 47.8 51.2 42.9 57.9 49.7 45.8 31.6 50.5 46.1 66.7 62.6 40.9 47.2 65.4 26.8 62.3 71.7 58.5 77.7 66.4 80.9 33.0 73.4 37.5 69.3 82.5 68.2 79.1 36.1 52.1 51.5 44.3 65.8 38.6 61.1 55.1 70.9 38.0 82.9 69.3 61.1 59.5 46.4 92.4 77.0 56.1 65.4 47.0 78.5 60.6 51.0 35.7 69.1 68.8 37.1 40.3 99.2 36.4 51.2 60.9 52.9 102.4 65.8 40.5 49.3 73.2 50.4 67.7 55.7 13.3 33.8 14.1 20.3 37.6 19.6 25.1 17.7 19.2 44.0 19.5 15.1 17.6 3.2 22.2 31.5 28.9 24.0 34.1 13.2 14.1 14.3 15.7 13.8 15.1 13.3 14.0 13.7 12.8 14.7 14.9 28.4 22.4 35.9 54.9 39.2 47.0 56.0 169.3 44.9 0.0 50.7 41.3 67.8 71.4 84.0 53.3 0.0 82.8 41.2 98.1 181.9 153.3 569.2 48.8 37.5 31.6 79.8 74.6 47.0 109.4 119.1 40.0 46.4 40.1 37.3 29.3 33.2 289.4 164.2 0.0 50.9 97.0 150.5 65.7 40.3 166.5 28.9 67.5 81.8 22.5 103.9 0.0 30.9 58.8 58.6 93.0 69.7 58.3 70.9 84.9 213.3 508.1 79.0 0.0 32.9 30.0 141.3 435.4 104.4 129.8 54.1 127.8 34.5 74.4 165.5 65.2 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" 14 64388031-64463457 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 142.9;Proximal tubular cells: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 56.4 18.0 8.6 20.0 17.4 27.0 29.8 8.3 12.3 16.9 15.0 23.3 19.7 16.1 9.9 25.1 16.0 13.1 28.1 12.9 8.1 55.3 356.9 15.4 23.6 7.5 7.8 24.9 23.8 27.5 9.2 13.3 7.0 12.9 27.5 3.6 15.6 13.8 64.1 17.1 18.9 20.0 7.2 14.5 17.9 4.7 8.9 30.2 20.5 61.9 27.7 18.6 16.6 8.3 294.1 164.9 58.5 143.6 70.5 53.4 95.7 106.4 83.3 148.1 147.4 161.2 144.2 103.3 49.6 67.1 68.3 146.0 177.6 111.2 160.4 107.3 117.9 122.2 143.5 131.8 50.6 104.5 81.2 43.0 37.3 124.3 66.4 57.5 93.1 98.1 108.5 98.7 114.7 270.1 179.9 62.3 118.0 186.5 160.4 138.3 201.2 114.4 110.5 160.9 128.7 49.0 183.7 111.4 58.3 54.0 164.4 58.6 51.5 115.1 184.1 102.2 134.2 58.8 65.6 177.9 107.4 125.2 134.8 0.4 11.7 0.1 9.7 19.5 13.0 27.0 10.1 12.3 17.7 15.3 7.8 10.7 0.9 17.8 16.7 4.0 19.5 12.2 8.6 17.4 8.3 12.3 12.9 8.1 7.5 7.8 7.0 7.2 8.9 8.3 8.1 19.2 23.5 15.0 16.2 13.8 14.2 14.7 13.6 0.0 9.8 8.1 43.9 15.7 19.5 16.5 0.0 30.6 10.8 7.9 41.1 16.9 1.4 6.8 11.7 12.3 3.0 42.3 19.5 10.3 30.9 14.9 15.3 8.7 50.7 27.2 12.8 142.9 25.3 0.0 15.6 14.3 2.0 13.0 11.0 1.5 13.1 12.3 14.2 8.4 13.3 0.0 8.2 14.1 10.9 11.7 6.3 13.2 24.1 10.2 8.2 75.3 11.5 0.0 19.7 13.1 19.3 0.9 8.9 19.5 10.7 9.9 16.6 21.4 24.6 12.7 MTURN "C7orf41, Ells1, FLJ25903" ENSG00000180354 "Maturin, neural progenitor differentiation regulator homolog" Q8N3F0 7 30134986-30162762 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 14 "brain: 1933.2;choroid plexus: 740.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 156.5" "Cancer enhanced" "Detected in all" "glioma: 29.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 8.2;NK-cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 52.9;HEL: 96.2;SCLC-21H: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029507 Enhanced Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA029507: AB_10601149" "unprognostic (1.99e-1)" "unprognostic (1.38e-2)" "unprognostic (3.70e-1)" "unprognostic (7.14e-2)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.89e-3)" "unprognostic (9.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.11e-3)" "unprognostic (8.11e-3)" "prognostic favorable (7.64e-13)" "unprognostic (9.50e-2)" "unprognostic (7.64e-2)" "unprognostic (4.64e-1)" "unprognostic (3.26e-1)" 88.4 10.8 1190.3 9.7 1373.7 23.3 41.6 1103.3 1933.2 25.7 740.3 35.8 5.4 19.4 95.3 19.5 21.1 10.4 25.0 946.3 1044.1 50.3 4.1 20.9 5.4 1359.2 1275.8 33.4 12.9 15.7 17.4 7.5 1312.7 19.2 10.0 41.0 35.2 23.8 36.6 23.2 13.8 17.0 1311.0 8.3 26.4 10.9 1260.6 7.5 14.7 59.8 5.4 32.1 20.0 1483.6 12.5 2.1 7.1 7.6 52.9 35.9 6.4 6.0 7.0 2.0 2.8 1.0 5.0 0.7 4.8 13.3 11.0 2.4 16.4 23.6 6.4 5.4 13.2 96.2 16.1 6.7 4.1 4.8 30.8 17.9 10.8 6.2 10.9 8.6 3.2 13.1 6.4 5.0 13.8 4.8 5.6 2.3 4.9 11.6 7.5 0.5 16.3 21.4 24.1 5.1 68.7 18.2 3.8 19.1 19.4 6.6 13.5 7.1 15.5 7.8 8.5 16.6 8.5 8.3 12.7 1.1 10.4 10.3 4.0 8.2 0.3 3.6 0.3 0.2 0.1 0.5 0.2 0.1 0.4 0.3 0.1 0.3 2.2 2.1 0.0 1.0 0.7 1.4 1190.3 1373.7 1103.3 1933.2 946.3 1044.1 1359.2 1275.8 1312.7 1311.0 1260.6 1483.6 38.9 16.0 20.0 18.6 5.6 37.5 17.8 6.6 13.1 0.0 48.3 40.8 27.6 17.2 10.2 44.1 0.0 2.6 32.1 3.2 156.5 8.3 14.1 46.6 16.9 18.9 54.1 35.1 55.9 8.6 7.3 24.6 7.7 52.6 6.3 16.6 26.0 5.0 5.3 0.0 34.7 9.1 0.0 23.4 16.8 32.5 17.1 29.3 55.2 37.5 12.1 0.0 6.2 16.6 77.1 10.4 5.9 12.4 4.9 26.6 0.4 11.2 26.6 0.0 6.6 17.8 30.2 2.0 7.3 11.4 36.8 2.2 7.4 5.9 6.0 23.0 MTUS2 "CAZIP, ICIS, KIAA0774, TIP150" ENSG00000132938 "Microtubule associated scaffold protein 2" Q5JR59 13 28820339-29505947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "heart muscle: 50.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 548.4;Inhibitory neurons: 671.8" "Cancer enhanced" "Detected in some" "urothelial cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 13.2;HeLa: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031473, HPA031474, HPA031475" Enhanced Supported "Microtubules,Cytokinetic bridge" Yes NA "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Microtubules, Cytokinetic bridge" "HPA031473: AB_2673901, HPA031474: AB_10600109, HPA031475: AB_10600442" "unprognostic (1.67e-1)" "unprognostic (3.07e-1)" "unprognostic (1.96e-1)" "unprognostic (3.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.22e-2)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (1.30e-3)" "unprognostic (3.45e-2)" "unprognostic (3.91e-5)" "unprognostic (2.51e-2)" "unprognostic (5.46e-2)" "unprognostic (5.93e-2)" "unprognostic (9.62e-2)" 0.2 0.2 0.4 0.1 1.7 0.1 0.1 1.2 9.7 0.6 1.8 0.9 0.1 1.5 0.0 0.3 0.8 0.1 50.2 1.0 0.0 0.1 0.9 0.1 0.6 0.0 0.1 7.5 4.8 0.0 6.1 0.0 0.0 0.3 0.2 4.6 1.0 0.1 0.1 0.2 0.4 1.2 2.2 0.5 1.3 1.2 1.0 0.2 0.5 0.1 0.1 1.3 0.2 2.4 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.2 13.2 0.4 0.0 0.0 0.0 0.5 0.0 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.0 0.0 2.3 1.6 0.1 0.4 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.7 1.2 9.7 1.0 0.0 0.0 0.1 0.0 2.2 1.0 2.4 0.1 0.0 0.5 10.4 0.1 0.5 0.7 0.1 0.0 0.0 0.3 0.4 145.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.3 1.0 0.7 0.0 0.8 548.4 0.6 0.0 5.9 0.0 1.1 0.0 1.2 0.4 0.5 0.1 0.0 671.8 0.7 0.0 0.0 0.8 3.3 0.9 0.2 1.8 15.0 0.1 0.0 0.0 18.1 16.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 3.6 0.0 0.0 1.6 1.0 0.1 4.1 1.8 0.1 0.3 0.3 19.6 0.0 1.1 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MXD4 "bHLHc12, MAD4, MST149, MSTP149" ENSG00000123933 "MAX dimerization protein 4" Q14582 4 2247432-2262109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 169.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053363 Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA053363: AB_2682128" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (2.84e-2)" "unprognostic (3.54e-2)" "prognostic favorable (2.21e-5)" "unprognostic (1.64e-1)" "unprognostic (5.94e-2)" "unprognostic (8.37e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.39e-5)" "unprognostic (5.65e-2)" "unprognostic (1.09e-3)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.12e-2)" 38.6 42.0 43.9 11.3 39.8 29.8 35.9 62.1 58.4 31.1 38.2 35.2 18.3 37.1 11.6 21.0 27.9 15.1 36.2 40.9 37.7 38.8 20.6 38.5 20.2 40.6 40.5 23.2 25.3 12.4 63.5 14.3 39.7 33.0 7.2 5.9 35.0 25.0 24.1 25.9 28.6 14.0 37.5 57.6 31.2 22.1 41.2 23.2 33.4 14.4 9.1 25.1 19.4 39.6 2.3 8.3 12.9 15.5 44.2 32.6 3.0 16.4 16.6 12.0 12.2 2.0 7.1 7.1 36.1 25.0 6.4 11.2 3.7 13.0 3.1 6.3 39.5 1.3 29.0 23.6 32.4 5.5 14.5 51.1 22.9 3.9 6.1 26.5 28.9 10.3 9.8 11.6 11.3 16.2 12.6 31.6 5.1 9.6 36.4 8.5 4.4 15.1 14.2 13.0 20.8 38.7 15.4 7.5 12.3 15.7 35.2 34.4 68.7 13.3 5.3 9.9 3.7 17.6 13.2 2.8 18.2 4.9 4.0 7.2 2.7 3.4 3.3 3.0 2.7 2.2 3.0 3.3 2.5 2.0 1.5 1.5 1.1 2.0 3.0 7.2 4.0 1.4 43.9 39.8 62.1 58.4 40.9 37.7 40.6 40.5 39.7 37.5 41.2 39.6 169.7 19.2 19.9 48.0 37.9 19.1 15.3 13.6 7.4 81.6 67.8 67.1 18.4 17.2 16.1 60.7 87.6 44.3 129.6 47.9 15.6 16.5 10.1 39.6 81.9 54.7 33.6 20.6 11.6 18.3 48.4 53.6 23.0 42.8 24.1 37.9 103.5 35.5 50.3 65.6 20.5 55.9 10.2 72.9 27.5 28.8 33.2 58.8 23.2 27.2 21.6 67.9 68.0 19.1 19.7 17.5 31.8 56.4 54.0 28.7 44.0 22.1 13.4 97.1 26.3 39.6 48.5 7.0 37.0 17.3 26.3 32.7 54.7 100.5 38.2 13.1 MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 149.5;Extravillous trophoblasts: 259.9;Fibroblasts: 183.3;Leydig cells: 176.1;Peritubular cells: 183.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.0;BJ: 143.6;BJ hTERT+: 66.9;fHDF/TERT166: 71.9;HSkMC: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" 103.6 11.7 2.9 8.2 2.5 0.6 70.0 1.1 2.9 100.4 1.7 58.2 6.3 117.2 2.6 17.6 57.4 19.4 42.8 4.0 2.4 26.4 7.4 53.9 2.5 5.9 4.5 81.9 8.7 1.1 21.7 11.6 2.6 39.0 1.7 0.8 32.4 11.4 16.6 41.6 29.5 6.4 2.3 26.4 28.9 14.7 3.2 0.6 46.6 5.0 0.8 52.8 59.3 3.0 4.1 0.8 1.2 1.0 16.5 46.0 42.3 143.6 66.9 16.6 19.9 8.0 3.3 1.7 0.6 71.9 0.1 3.0 1.0 0.0 3.2 3.2 1.3 1.2 3.1 12.8 43.4 0.2 1.6 54.8 0.0 6.2 0.0 32.4 0.0 0.9 17.3 1.4 21.5 0.4 0.4 0.5 14.0 0.3 4.7 0.6 0.3 0.4 0.0 0.7 3.2 8.9 0.5 1.4 0.1 10.4 11.1 0.7 1.3 0.7 23.1 21.8 0.6 3.3 0.3 0.2 5.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.2 2.9 2.5 1.1 2.9 4.0 2.4 5.9 4.5 2.6 2.3 3.2 3.0 22.2 3.2 0.0 7.5 0.5 10.7 1.1 0.7 2.2 0.7 7.0 47.9 3.5 0.0 0.0 9.2 0.0 9.5 1.1 0.0 0.0 5.7 1.7 4.3 149.5 5.1 0.0 0.0 0.3 0.0 259.9 183.3 2.6 3.7 0.0 0.5 6.4 0.1 9.3 0.0 0.4 0.0 0.0 0.0 19.7 11.4 176.1 1.7 10.6 6.5 0.7 50.7 0.0 0.0 0.1 1.1 0.0 183.6 1.4 0.6 0.0 1.4 0.0 1.5 13.1 65.8 74.7 0.7 5.4 1.3 10.5 29.4 2.2 0.8 0.0 0.3 MYB c-myb ENSG00000118513 "MYB proto-oncogene, transcription factor" P10242 6 135181308-135219173 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 35.2;breast: 20.1;intestine: 26.5;lymphoid tissue: 66.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 47.8;Erythroid cells: 83.2;granulocytes: 26.0;Intestinal goblet cells: 32.7;Ionocytes: 26.4;Respiratory ciliated cells: 37.2;Undifferentiated cells: 52.0" "Group enriched" "Detected in many" 5 "breast cancer: 17.7;colorectal cancer: 16.4;stomach cancer: 5.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 4.6;eosinophil: 5.4;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 5.4" "Cell line enhanced" "Detected in many" "HL-60: 219.8;MOLT-4: 403.1;NB-4: 208.5;REH: 244.9;THP-1: 343.8;U-937: 186.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017704, HPA071605" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB017704: , HPA071605: " "unprognostic (1.69e-1)" "unprognostic (5.82e-2)" "unprognostic (1.82e-3)" "unprognostic (1.37e-2)" "unprognostic (4.06e-1)" "unprognostic (8.35e-3)" "unprognostic (1.13e-3)" "unprognostic (2.48e-2)" "unprognostic (6.44e-2)" "unprognostic (1.00e-1)" "unprognostic (3.71e-2)" "prognostic favorable (9.65e-4)" "unprognostic (2.41e-11)" "prognostic favorable (9.87e-4)" "unprognostic (8.35e-2)" "unprognostic (3.04e-2)" "unprognostic (9.40e-2)" 0.3 0.5 1.6 5.3 1.7 35.2 20.1 0.0 0.7 1.6 0.4 25.3 10.9 1.0 0.1 3.0 8.4 0.9 0.1 0.3 0.2 0.1 0.4 2.0 6.3 0.9 1.0 0.0 0.3 3.6 0.0 0.4 0.6 1.4 26.5 0.3 0.6 0.9 0.1 3.0 9.4 1.4 0.2 1.2 2.0 0.7 0.3 66.1 0.1 0.0 7.0 1.1 1.3 0.1 1.8 0.3 1.9 3.0 0.0 0.1 0.3 1.0 0.6 1.1 1.1 0.3 1.4 10.9 0.4 0.3 0.4 0.9 5.6 0.0 0.7 18.0 2.5 138.8 1.0 0.5 0.1 219.8 105.1 0.0 0.1 0.6 0.0 0.5 0.3 133.4 114.6 20.1 1.1 11.6 403.1 208.5 1.5 19.2 1.7 244.9 5.9 33.2 0.3 1.5 10.5 6.9 0.5 10.4 0.6 0.5 7.9 343.8 0.4 0.3 1.6 7.9 2.4 27.7 7.7 66.0 0.1 186.1 2.3 4.6 0.7 5.4 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.4 0.2 1.6 1.7 0.0 0.7 0.3 0.2 0.9 1.0 0.6 0.2 0.3 0.1 0.2 0.0 1.3 0.0 2.3 2.7 1.3 1.3 0.6 0.9 47.8 12.6 0.4 2.8 7.1 0.0 0.0 1.4 9.1 18.1 0.0 0.0 0.1 24.3 0.3 0.3 17.6 83.2 0.6 0.8 0.4 0.5 4.6 2.2 26.0 0.4 0.0 0.0 1.1 0.0 2.7 32.7 26.4 1.2 1.7 0.2 0.0 2.1 8.8 0.0 2.8 0.9 0.0 0.0 0.2 0.1 10.2 0.0 4.6 2.1 2.3 0.0 37.2 0.0 0.0 0.6 0.9 0.0 1.8 10.2 7.0 0.3 3.6 0.1 52.0 2.2 MYCBP2 "FLJ10106, KIAA0916, PAM, PHR1" ENSG00000005810 "MYC binding protein 2" O75592 13 77044657-77327094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 425.4;Inhibitory neurons: 471.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA058807: AB_2732627" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favorable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" 69.9 22.2 42.3 19.0 46.2 32.8 49.3 37.3 52.4 43.4 18.8 29.4 9.0 27.2 29.8 45.9 29.2 12.5 32.9 48.6 35.9 22.6 24.5 28.3 40.0 34.6 29.6 43.1 30.9 14.9 32.3 10.9 36.9 28.0 12.5 28.9 29.1 13.3 26.5 79.7 34.8 11.9 30.1 56.4 24.9 26.3 33.9 34.6 27.2 18.1 37.8 30.4 41.5 38.7 21.6 10.8 12.9 14.1 62.9 27.9 7.5 13.4 19.8 11.5 14.7 9.7 11.0 61.4 8.3 26.6 11.2 19.5 22.4 24.7 15.5 24.5 22.2 52.2 22.2 20.1 21.4 110.8 17.7 31.5 20.2 10.6 20.8 11.4 26.5 22.3 11.3 18.8 20.7 13.1 30.5 74.3 6.8 28.7 13.6 34.2 13.1 15.0 19.6 21.1 20.2 9.4 16.2 23.1 12.8 13.0 8.6 83.8 35.0 10.9 9.1 7.3 13.0 20.3 15.0 42.7 22.1 89.2 11.3 1.4 2.0 2.0 3.2 2.1 2.8 4.9 3.6 2.8 1.9 4.3 4.1 3.2 1.8 2.8 1.6 2.7 4.5 1.4 42.3 46.2 37.3 52.4 48.6 35.9 34.6 29.6 36.9 30.1 33.9 38.7 92.2 38.5 52.2 158.7 170.3 82.3 39.9 32.6 63.7 229.3 36.8 38.4 69.7 25.8 30.9 35.0 104.3 46.1 109.2 14.2 1.9 26.1 56.0 50.9 61.1 83.8 32.6 46.9 425.4 33.1 31.5 80.6 38.2 66.6 48.2 34.0 44.6 52.4 41.8 218.7 471.3 19.7 26.4 106.9 48.2 23.4 65.9 100.4 32.0 282.9 116.7 121.5 120.5 338.8 212.5 30.2 15.8 96.3 121.9 53.7 15.2 13.2 19.5 94.8 105.2 76.7 76.0 81.5 71.6 129.1 150.7 43.9 121.5 67.4 28.1 42.4 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 172.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" 20.1 14.2 6.9 43.5 7.4 51.8 15.0 7.2 7.5 15.2 8.0 30.3 32.2 12.1 18.6 36.6 14.4 23.5 9.4 6.7 7.7 13.7 61.1 42.6 35.2 9.5 7.5 11.4 11.6 11.6 9.2 22.6 8.0 14.3 31.7 2.1 18.0 12.0 3.2 17.7 32.2 24.5 8.6 40.7 27.6 7.7 9.2 38.3 9.4 8.8 41.6 47.4 20.3 8.5 25.1 34.2 5.9 33.2 25.0 32.0 10.8 23.6 39.0 68.1 72.9 22.7 30.9 52.8 13.8 44.7 15.8 30.9 43.2 24.2 22.1 39.5 8.7 28.5 16.6 36.6 21.4 36.2 72.0 38.4 26.6 39.2 15.3 13.2 39.9 40.3 13.3 22.3 36.8 25.7 61.3 12.2 22.1 52.8 35.7 24.8 7.0 23.1 37.6 58.9 3.0 12.0 33.4 172.1 22.3 4.8 25.8 40.8 35.5 13.8 7.9 60.6 24.0 28.9 32.9 38.5 25.0 63.0 28.9 288.5 236.9 296.9 67.2 333.6 58.1 43.7 60.6 69.3 203.6 35.2 42.1 59.5 284.7 54.6 436.1 99.9 87.4 257.3 6.9 7.4 7.2 7.5 6.7 7.7 9.5 7.5 8.0 8.6 9.2 8.5 13.4 6.4 15.2 2.0 19.5 14.4 13.5 12.7 14.2 1.0 11.3 10.8 1.6 5.7 16.4 5.5 0.0 14.6 35.3 40.8 7.9 24.5 1.4 10.9 30.2 15.9 9.6 9.7 0.2 27.3 24.4 10.8 23.9 18.6 24.1 10.0 10.4 33.2 32.2 0.0 0.4 14.9 10.2 75.4 40.5 0.9 13.7 61.5 3.6 1.9 58.1 4.1 28.8 2.5 0.3 64.0 34.8 10.5 12.9 16.0 28.0 12.2 12.1 0.1 13.1 4.3 7.2 8.6 0.6 15.1 17.2 12.0 19.6 10.2 15.9 49.4 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adipose tissue: 7.7;breast: 6.9;pancreas: 5.6;stomach 1: 2.3" "Group enriched" "Detected in some" 4 "Adipocytes: 5.5;Distal tubular cells: 3.9;Exocrine glandular cells: 2.2;Extravillous trophoblasts: 1.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 106 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 106 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 31 "RH-30: 134.6" "Not detected" "Not detected" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (6.86e-2)" "unprognostic (6.51e-3)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-2)" "unprognostic (2.10e-3)" "unprognostic (4.32e-1)" "unprognostic (1.77e-1)" "unprognostic (8.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.01e-4)" "unprognostic (1.63e-2)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.67e-1)" 7.7 0.1 0.0 0.2 0.0 0.0 6.9 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.5 1.0 0.0 0.0 0.7 0.1 0.4 0.6 0.1 0.0 0.1 5.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.0 0.4 0.9 0.5 0.1 0.0 0.8 2.3 0.4 0.0 0.8 0.4 0.2 0.3 0.5 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 134.6 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.2 1.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MYO16 "KIAA0865, Myo16b, MYR8, NYAP3, PPP1R107" ENSG00000041515 "Myosin XVI" Q9Y6X6 13 108596152-109208005 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4" "Group enriched" "Detected in some" 8 "Inhibitory neurons: 460.0;Oligodendrocyte precursor cells: 299.6" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;SH-SY5Y: 4.5;U-2197: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 72.6" "Low region specificity" "Detected in all" "HPA040110, HPA058769, HPA071948" Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA040110: AB_10796339, HPA058769: AB_2683814, HPA071948: AB_2686475" "unprognostic (7.55e-3)" "unprognostic (7.74e-3)" "unprognostic (4.52e-4)" "unprognostic (5.12e-3)" "unprognostic (1.38e-1)" "unprognostic (5.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.53e-1)" "unprognostic (6.50e-2)" "unprognostic (9.01e-3)" "unprognostic (5.29e-2)" "unprognostic (4.68e-4)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "unprognostic (7.06e-2)" "unprognostic (2.34e-2)" 1.4 0.7 2.5 0.2 4.9 0.0 0.2 1.2 3.7 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.9 5.4 1.8 0.0 1.9 0.2 0.2 0.6 1.5 0.0 0.1 0.0 1.7 0.1 2.3 0.2 0.1 0.4 0.1 0.7 0.0 0.1 0.0 0.4 2.6 0.0 0.0 1.1 2.6 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.9 1.2 3.7 5.4 1.8 0.6 1.5 2.3 2.6 2.6 0.9 1.0 0.0 0.6 19.6 0.0 0.3 0.0 0.4 0.0 4.2 0.1 0.3 3.7 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.5 11.3 0.5 1.1 0.1 0.0 3.4 44.6 0.0 0.1 0.8 0.0 0.3 1.3 0.1 0.0 5.9 0.1 0.0 460.0 0.0 0.0 0.0 0.3 11.4 0.9 0.1 1.8 8.4 0.0 2.8 0.0 299.6 4.7 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.4 0.0 0.1 0.1 5.0 7.7 0.0 0.0 0.3 0.3 1.6 0.0 0.0 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 3800000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: AB_2667469" "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 169.3 27.0 12.4 34.4 11.8 4.9 115.9 13.3 12.7 77.4 17.1 104.9 47.4 97.1 21.5 64.7 66.4 46.1 97.5 10.2 14.7 56.8 39.5 87.2 24.1 14.8 11.2 43.6 69.3 34.3 22.9 56.9 14.6 69.9 41.7 2.1 91.7 58.2 49.5 57.7 65.6 65.7 11.9 30.8 76.3 17.1 13.7 21.3 60.6 35.8 25.1 86.3 67.8 10.8 169.8 182.1 19.3 79.5 88.8 87.6 74.2 168.6 138.9 108.7 91.0 122.3 90.7 16.9 118.7 261.1 72.7 139.9 29.2 117.2 56.3 75.2 74.5 16.2 96.4 46.2 131.7 1.6 81.5 68.7 57.3 100.2 57.3 99.5 141.7 10.5 13.1 13.7 93.5 129.5 1.9 1.4 12.4 105.8 34.0 6.9 26.4 30.7 100.5 86.9 7.8 43.0 105.9 152.6 67.4 47.5 125.3 8.7 187.9 156.6 119.1 77.7 147.8 10.7 9.1 7.2 124.7 4.1 138.8 0.1 0.9 0.0 0.9 2.0 0.4 4.8 2.1 0.9 1.1 3.8 0.7 0.4 0.5 0.0 1.7 1.0 1.9 1.5 12.4 11.8 13.3 12.7 10.2 14.7 14.8 11.2 14.6 11.9 13.7 10.8 133.7 125.0 35.9 5.5 20.8 39.8 38.2 27.8 31.9 4.1 44.0 33.0 75.4 48.6 36.3 86.5 0.0 57.8 2.5 159.0 21.5 62.3 17.4 26.3 44.4 78.0 39.5 13.5 2.5 52.0 28.4 51.8 66.3 75.5 12.0 25.4 83.6 38.5 20.0 5.0 3.8 111.8 14.2 14.5 43.4 11.4 42.3 16.7 64.0 15.0 20.3 5.6 0.0 2.5 1.0 92.8 88.7 48.5 12.8 64.7 92.8 15.4 12.9 2.1 118.3 37.7 90.6 9.4 7.5 39.5 42.6 47.6 10.0 10.6 88.1 39.2 MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.6;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "dendritic cells: 81.3;Langerhans cells: 65.1;Macrophages: 74.2;monocytes: 392.2;NK-cells: 252.4;T-cells: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 52.6;HEL: 64.1;HL-60: 39.9;JURKAT: 85.9;MOLT-4: 97.3;NB-4: 52.1;THP-1: 68.6;U-937: 57.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Nucleoplasm "HPA021252: AB_1854254" "unprognostic (2.74e-2)" "prognostic favorable (8.26e-4)" "unprognostic (5.20e-3)" "unprognostic (9.91e-3)" "unprognostic (1.27e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.54e-3)" "unprognostic (6.47e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (8.71e-8)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (7.92e-2)" 2.2 0.8 0.4 16.6 0.3 43.6 1.0 0.3 0.6 0.8 0.3 2.0 3.3 0.7 0.3 1.5 1.2 3.5 0.9 0.3 1.0 0.9 1.3 12.0 25.1 1.4 0.7 0.3 0.7 0.1 0.5 1.2 0.6 1.1 1.8 0.0 2.3 0.7 0.3 0.9 7.8 2.8 0.6 19.0 3.3 0.4 1.6 27.2 1.6 0.4 14.8 6.1 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 52.6 0.0 64.1 2.7 0.0 0.0 39.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 85.9 0.0 0.0 0.0 0.0 97.3 52.1 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 57.3 0.0 41.5 58.3 18.5 61.5 95.5 38.4 27.7 40.5 55.6 42.7 18.9 14.1 29.6 6.0 23.9 129.8 4.5 79.9 79.9 0.4 0.3 0.3 0.6 0.3 1.0 1.4 0.7 0.6 0.6 1.6 0.8 0.9 3.2 7.7 0.0 55.7 2.8 0.4 0.0 0.0 0.2 1.2 1.3 1.1 1.5 1.3 0.0 0.0 0.2 81.3 0.2 0.0 0.3 0.6 0.3 0.5 1.0 0.0 6.3 0.1 1.1 0.3 2.3 2.0 0.6 30.4 0.4 2.2 1.4 10.5 3.3 0.0 0.2 0.0 58.7 65.1 1.6 0.0 74.2 3.6 0.0 392.2 0.3 252.4 0.5 0.0 0.2 0.1 0.4 33.4 0.4 0.0 0.6 0.7 0.2 6.6 2.0 1.4 3.8 1.2 0.2 1.7 0.1 87.1 1.2 0.1 0.2 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 55.5;Exocrine glandular cells: 11.8;Pancreatic endocrine cells: 10.3;Proximal tubular cells: 9.2;Syncytiotrophoblasts: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 35.4;SK-BR-3: 56.8;T-47d: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" 8.1 6.2 30.6 3.4 30.3 2.0 3.4 27.1 31.5 1.7 16.8 19.0 27.3 2.7 1.9 5.3 4.5 6.1 3.9 28.4 28.2 14.5 41.5 3.2 1.5 34.0 33.5 1.0 11.1 1.5 5.5 19.8 28.7 3.2 16.2 3.4 5.6 5.2 84.2 3.7 25.8 4.4 24.5 1.4 15.0 1.3 31.8 1.1 1.9 39.2 1.8 3.1 2.4 24.2 8.1 5.5 9.2 5.6 3.8 1.2 19.7 1.4 1.1 0.8 1.3 13.9 8.3 4.4 15.9 1.4 4.0 16.4 6.7 15.5 1.1 1.4 3.6 0.8 24.6 35.4 0.5 0.8 2.7 1.8 7.2 2.6 3.0 4.3 3.8 3.3 1.1 4.2 2.0 13.4 2.5 1.2 5.5 27.4 4.4 4.0 4.6 1.3 4.9 2.9 1.3 13.0 10.8 56.8 0.9 7.8 52.8 1.3 3.2 1.8 11.0 1.6 3.5 2.8 6.5 1.6 1.6 3.1 1.6 0.4 0.1 0.2 0.7 0.1 0.5 0.2 0.4 0.4 0.0 0.2 0.2 0.3 0.3 0.4 0.1 0.1 0.6 0.1 30.6 30.3 27.1 31.5 28.4 28.2 34.0 33.5 28.7 24.5 31.8 24.2 3.9 9.6 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 0.0 2.5 3.7 0.0 55.5 0.3 0.0 1.9 5.7 0.0 3.4 0.7 2.1 0.0 0.0 0.0 11.8 3.6 1.1 0.0 2.0 1.3 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 9.2 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 17.4 0.3 0.1 0.0 0.0 MYZAP "GCOM1, Gup, Gup1, MYOZAP" ENSG00000263155 "Myocardial zonula adherens protein" P0CAP1 15 57591904-57685364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 588.9" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 481.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 137.3;hTERT-HME1: 24.0;HUVEC TERT2: 28.3;OE19: 47.5;RT4: 25.1;TIME: 33.1" HPA039827 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA039827: AB_10673364" "unprognostic (1.30e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (9.26e-3)" "unprognostic (1.49e-1)" "unprognostic (6.10e-3)" "unprognostic (5.19e-2)" "unprognostic (8.92e-2)" "unprognostic (2.30e-2)" "unprognostic (1.26e-1)" "unprognostic (9.67e-2)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-1)" "unprognostic (3.86e-2)" "unprognostic (1.77e-2)" 65.3 54.7 2.0 2.6 2.4 4.0 22.3 6.3 1.8 17.3 1.3 18.1 16.8 29.4 1.8 41.4 4.7 4.8 588.9 1.8 2.5 5.7 2.4 31.8 6.0 6.7 2.8 5.1 35.1 0.6 1.7 56.6 7.7 19.8 11.8 1.3 18.3 38.2 11.6 9.6 15.4 17.2 1.6 12.4 23.4 2.5 3.5 1.4 3.7 15.5 8.6 84.1 26.9 1.7 6.0 1.7 0.0 10.5 2.3 0.1 3.2 0.9 8.6 1.4 1.7 7.3 4.1 0.1 0.7 0.0 8.9 2.6 0.0 4.4 1.7 0.0 0.2 137.3 1.7 0.1 0.4 0.0 0.1 0.0 3.1 0.3 24.0 0.1 28.3 0.2 1.9 0.0 0.7 2.3 0.0 0.1 0.1 47.5 2.4 0.0 11.4 0.3 0.0 25.1 0.0 4.1 0.6 5.9 0.0 1.2 7.9 0.1 33.1 0.1 2.6 0.4 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.4 0.0 0.0 3.4 2.0 0.0 0.5 0.0 0.8 0.0 0.2 2.4 2.0 2.4 6.3 1.8 1.8 2.5 6.7 2.8 7.7 1.6 3.5 1.7 22.9 9.6 0.6 0.0 0.3 0.0 10.2 0.0 0.0 0.3 3.0 1.0 481.4 5.7 0.6 25.8 0.0 4.4 0.0 26.9 7.9 32.5 0.1 1.1 3.0 15.1 1.8 1.3 0.0 18.9 2.4 9.8 7.1 3.5 0.0 65.1 4.6 0.2 1.4 0.0 0.0 7.9 0.0 7.9 0.0 0.7 4.7 8.7 0.0 0.0 3.4 0.6 0.0 0.0 0.0 21.5 24.9 17.0 0.0 11.0 18.1 0.3 0.7 0.2 0.0 0.2 8.1 0.0 1.6 0.0 0.0 1.2 0.2 13.2 6.6 22.4 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 NACC2 "BEND9, BTBD14A, BTBD31, MGC23427" ENSG00000148411 "NACC family member 2" Q96BF6 9 136006537-136095289 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 120.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047924, HPA052962" Approved Approved Nucleoli,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Mitochondria" "HPA047924: AB_2680212, HPA052962: AB_2681998" "unprognostic (1.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.90e-2)" "unprognostic (8.73e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (9.25e-3)" "unprognostic (2.25e-2)" "unprognostic (1.23e-1)" "unprognostic (4.92e-2)" "unprognostic (1.15e-2)" "unprognostic (2.23e-1)" "prognostic favorable (8.28e-5)" "prognostic favorable (8.63e-4)" "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (4.12e-2)" 12.3 11.4 80.9 8.7 100.0 2.0 8.0 115.6 74.1 9.7 26.5 32.7 6.2 20.9 4.1 8.5 12.8 7.2 16.7 52.8 81.0 7.5 9.6 9.5 3.4 113.2 104.9 7.7 7.6 4.6 6.4 2.6 112.3 11.8 3.8 4.9 7.9 17.3 17.0 4.5 9.9 15.6 85.8 8.1 13.6 6.5 120.6 1.0 5.8 6.8 2.0 23.2 7.3 91.9 6.1 32.7 3.6 49.0 15.4 8.6 4.5 14.6 9.7 4.6 1.6 14.0 10.6 0.0 17.1 23.2 7.4 23.3 7.9 7.9 1.5 18.6 7.1 4.1 33.3 17.6 15.6 0.0 7.4 14.4 7.2 4.3 4.3 18.8 13.0 0.0 12.8 0.1 9.0 20.5 0.0 11.6 11.0 9.7 20.2 0.0 3.8 10.0 19.2 6.9 1.2 1.5 20.6 17.0 18.2 16.2 17.4 37.9 21.6 12.3 13.9 10.5 10.1 0.1 0.0 0.3 16.2 1.4 25.2 1.9 2.2 0.8 0.8 1.7 0.3 0.0 0.3 0.7 1.2 0.0 0.2 0.2 2.7 0.2 1.7 0.1 0.2 0.8 80.9 100.0 115.6 74.1 52.8 81.0 113.2 104.9 112.3 85.8 120.6 91.9 14.3 12.8 5.0 69.9 0.8 4.6 4.9 9.0 3.4 3.4 6.7 5.6 28.5 7.2 7.9 5.5 0.0 0.7 7.0 12.4 0.0 12.6 76.2 18.9 9.8 18.5 2.4 1.7 2.5 13.4 2.1 10.9 7.7 6.0 2.5 1.5 17.9 33.2 7.8 3.3 21.1 4.4 0.0 38.4 8.0 305.5 18.0 16.6 5.4 21.5 45.3 17.1 12.3 40.7 45.1 18.3 9.2 19.2 2.1 11.8 6.7 13.6 12.5 1.9 26.3 14.0 15.8 2.4 12.6 6.8 5.1 0.4 5.7 1.4 5.3 7.6 NADK FLJ13052 ENSG00000008130 "NAD kinase" O95544 1 1751232-1780457 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 506.2" "Group enriched" "Detected in all" 7 "granulocytes: 506.2;monocytes: 162.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048909, HPA053368" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "HPA048909: AB_2680553, HPA053368: AB_2682130" "unprognostic (1.29e-1)" "unprognostic (4.29e-1)" "unprognostic (7.07e-2)" "unprognostic (6.82e-2)" "unprognostic (1.98e-1)" "unprognostic (1.58e-2)" "unprognostic (3.32e-1)" "unprognostic (9.03e-2)" "unprognostic (7.81e-2)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (4.54e-3)" "unprognostic (1.40e-1)" "unprognostic (5.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" 53.6 81.8 24.8 37.5 26.6 100.7 44.7 22.1 29.0 28.6 27.8 45.1 38.0 30.9 13.3 29.9 36.1 23.3 28.7 24.1 24.3 30.2 134.0 40.3 41.2 25.4 24.6 37.2 38.9 17.2 26.4 26.0 25.0 32.9 25.4 10.9 40.2 17.4 19.6 28.3 43.3 19.8 24.5 93.1 43.2 27.5 26.5 16.4 31.7 19.2 26.6 32.3 27.1 23.8 41.6 39.3 34.4 50.7 47.8 34.5 44.2 40.9 35.5 45.6 40.3 42.1 74.2 54.5 30.4 30.5 14.7 34.6 37.3 32.5 20.3 53.5 59.1 44.7 65.0 73.6 46.2 63.4 72.1 40.6 28.9 28.4 40.3 24.8 44.9 42.6 55.9 75.8 34.4 47.4 48.1 54.8 23.5 69.4 43.8 60.4 29.4 113.1 39.7 33.9 46.2 35.2 45.8 99.2 43.7 20.3 34.2 43.6 43.8 33.1 23.7 34.6 37.5 67.1 32.7 121.8 32.7 69.3 17.6 84.2 141.3 329.7 7.4 158.6 8.8 10.8 4.3 5.9 45.9 12.1 2.8 4.1 506.2 3.8 162.6 37.9 7.0 82.9 24.8 26.6 22.1 29.0 24.1 24.3 25.4 24.6 25.0 24.5 26.5 23.8 29.0 12.8 30.7 14.4 27.2 9.8 15.7 11.2 13.6 7.9 21.4 17.9 6.8 25.8 21.6 14.7 16.7 24.5 46.8 57.8 15.6 19.1 14.9 18.7 22.2 20.8 22.8 15.8 10.2 29.4 26.3 18.7 52.0 22.8 2.5 21.2 22.5 94.3 36.6 6.7 10.4 38.7 16.2 58.4 13.7 26.7 37.6 45.0 8.8 9.4 67.3 5.7 27.8 10.6 11.1 28.7 34.6 34.6 26.0 34.7 28.6 24.3 13.5 17.7 13.1 12.6 18.2 12.4 22.4 19.5 12.8 42.8 15.4 44.2 31.0 27.5 NANOS1 "NOS1, ZC2HC12A" ENSG00000188613 "Nanos C2HC-type zinc finger 1" Q8WY41 10 119029714-119033730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" "Repressor, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 38.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 10.2;Cardiomyocytes: 11.3;Cone photoreceptor cells: 10.4;Muller glia cells: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 80.4;SK-BR-3: 46.7;SK-MEL-30: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB012219 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB012219: " "prognostic unfavorable (1.52e-4)" "unprognostic (1.17e-1)" "unprognostic (1.50e-3)" "unprognostic (1.59e-3)" "unprognostic (7.07e-3)" "unprognostic (2.01e-1)" "unprognostic (2.19e-2)" "unprognostic (4.76e-3)" "unprognostic (1.97e-1)" "unprognostic (2.70e-1)" "unprognostic (8.22e-3)" "unprognostic (8.79e-2)" "unprognostic (2.64e-4)" "unprognostic (7.89e-2)" "unprognostic (6.99e-2)" "unprognostic (2.78e-2)" "unprognostic (2.52e-3)" 9.5 11.3 7.4 0.3 7.3 0.2 8.3 7.4 7.7 1.9 5.0 2.9 0.3 2.1 1.7 1.0 1.0 0.2 10.3 5.9 11.8 4.6 0.3 1.1 0.4 8.8 8.9 0.3 2.2 0.3 2.8 6.3 8.5 1.0 0.4 4.1 1.3 0.9 38.6 1.6 0.9 1.8 7.1 0.3 3.4 1.9 9.2 0.3 7.1 1.7 0.3 3.3 1.0 10.9 16.4 1.3 2.2 0.4 7.4 1.1 9.7 0.4 0.5 0.4 0.2 2.0 5.6 8.7 2.2 0.1 0.0 5.8 2.7 2.9 0.7 2.6 6.6 0.2 3.8 1.8 3.5 1.0 0.0 1.5 11.7 0.1 1.6 2.4 0.4 3.0 1.7 1.0 0.5 2.3 2.2 2.8 7.1 3.4 1.3 0.0 2.7 5.9 3.1 1.3 6.3 80.4 4.7 46.7 37.4 12.2 7.4 4.7 0.5 0.0 3.4 0.1 0.8 2.4 8.6 3.2 0.7 2.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 7.4 7.3 7.4 7.7 5.9 11.8 8.8 8.9 8.5 7.1 9.2 10.9 5.7 6.4 1.1 2.0 1.3 0.8 5.0 1.3 0.6 4.1 10.2 6.1 11.3 1.5 1.2 1.8 10.4 6.5 6.3 4.4 0.0 0.6 0.2 3.9 2.8 1.7 3.0 0.0 0.5 0.2 0.4 4.0 1.1 3.7 0.0 2.6 0.7 0.1 0.7 1.7 2.3 3.8 0.0 0.0 2.1 0.1 1.8 0.9 0.0 0.0 0.0 14.7 1.0 2.0 0.2 0.3 0.1 0.7 1.6 2.9 0.2 0.5 1.2 2.1 0.0 7.7 3.9 0.4 1.0 0.8 1.3 1.0 2.9 0.7 2.1 1.3 NAPA ENSG00000105402 "NSF attachment protein alpha" P54920 19 47487637-47515091 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010100, HPA046149, HPA050196" Approved Uncertain Cytosol NA NA 2200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "CAB010100: AB_628263, HPA046149: AB_2679557, HPA050196: AB_2681048" "unprognostic (9.83e-2)" "unprognostic (9.43e-3)" "unprognostic (1.12e-2)" "unprognostic (1.76e-3)" "unprognostic (9.72e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (5.61e-2)" "unprognostic (2.42e-3)" "unprognostic (1.09e-3)" "prognostic favorable (4.26e-9)" "unprognostic (4.04e-2)" "unprognostic (4.17e-2)" "unprognostic (8.55e-2)" "unprognostic (2.90e-2)" 83.0 147.5 104.8 56.8 112.1 115.2 83.6 112.4 146.1 87.2 89.8 79.5 61.9 102.0 54.5 122.7 86.0 63.7 112.9 125.1 102.5 98.6 153.2 79.8 57.0 120.9 99.8 66.4 92.0 101.1 96.5 56.9 119.3 105.1 50.8 83.7 124.3 94.6 180.2 131.9 62.4 72.6 97.3 66.4 83.6 79.3 111.2 85.2 74.6 116.8 53.1 76.7 85.7 112.8 73.1 99.3 48.1 85.3 100.4 80.9 36.7 78.1 98.7 189.3 229.1 76.1 44.3 55.8 41.5 110.4 119.1 56.3 77.7 98.1 72.8 89.2 84.6 70.1 88.5 93.6 256.9 80.6 124.5 122.0 70.2 77.0 47.6 38.1 92.1 74.9 67.0 150.0 123.7 66.2 115.7 284.6 40.5 110.7 75.7 79.8 42.2 82.6 149.6 133.5 174.9 67.6 101.0 126.4 76.6 43.8 98.9 136.9 91.0 97.4 51.3 83.9 93.6 94.5 143.7 76.9 176.3 89.5 102.5 196.4 165.0 313.1 96.1 189.8 81.3 68.7 82.9 94.3 132.3 70.3 84.8 85.3 187.9 111.1 201.1 209.9 112.2 209.4 104.8 112.1 112.4 146.1 125.1 102.5 120.9 99.8 119.3 97.3 111.2 112.8 59.1 12.8 41.5 19.9 48.6 63.3 91.1 73.5 92.2 55.1 69.5 63.5 3.8 72.9 44.5 51.5 27.1 106.4 73.3 89.1 178.1 110.9 44.2 40.8 37.5 49.3 83.6 89.9 30.5 99.8 69.0 48.0 94.8 70.0 64.7 23.8 39.7 89.6 131.1 35.3 21.7 62.6 99.7 58.4 69.1 37.4 42.9 87.7 97.8 14.0 79.1 76.7 66.9 11.1 21.8 100.2 69.8 46.3 92.9 50.5 80.3 99.0 20.1 47.3 92.1 44.3 63.0 119.0 73.7 97.4 68.6 228.9 58.0 61.7 50.7 75.5 NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 43.5;brain: 99.0" "Cell type enhanced" "Detected in some" "Astrocytes: 126.7;Excitatory neurons: 46.0;Horizontal cells: 80.8;Inhibitory neurons: 37.6;Muller glia cells: 25.0" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 20.8;SCLC-21H: 25.8;SK-MEL-30: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 43.5 0.7 56.1 0.1 46.4 0.0 1.6 42.9 99.0 0.0 0.6 0.2 0.1 0.3 1.3 0.1 0.9 0.1 0.8 45.8 29.0 5.3 0.0 0.0 0.2 52.3 46.4 0.2 2.3 0.9 1.8 0.1 57.5 1.0 0.1 3.7 2.3 1.6 5.7 1.0 0.2 0.2 33.0 0.3 0.4 9.0 88.8 0.2 0.3 2.5 0.0 0.0 0.0 38.9 0.1 9.2 4.9 10.0 0.9 0.0 5.7 0.2 0.0 0.2 0.0 4.1 0.3 0.0 1.9 0.0 1.5 0.1 11.1 0.0 0.1 0.0 13.2 0.1 2.1 6.6 1.5 14.5 6.9 0.0 0.2 0.0 0.0 1.8 0.0 3.4 11.5 0.0 0.4 6.2 0.2 20.8 14.1 0.0 4.1 0.7 2.3 0.4 0.2 0.5 25.8 8.6 6.6 0.0 21.4 0.8 0.7 8.3 0.0 0.0 3.3 0.1 5.6 0.0 0.0 0.2 0.0 6.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 56.1 46.4 42.9 99.0 45.8 29.0 52.3 46.4 57.5 33.0 88.8 38.9 0.5 0.0 0.0 126.7 0.0 0.3 0.0 0.0 0.0 14.5 1.4 2.2 2.6 0.0 0.0 1.8 6.2 0.0 5.4 0.0 0.0 4.6 1.1 1.7 0.1 0.4 1.8 0.0 46.0 0.6 0.1 0.2 0.0 1.0 0.0 21.9 0.0 0.0 0.8 80.8 37.6 0.0 0.0 0.0 0.3 3.8 0.0 0.7 10.6 17.8 0.0 25.0 0.0 23.1 15.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.8 0.5 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 NATD1 "C17orf103, Gtlf3b, MGC33894" ENSG00000274180 "N-acetyltransferase domain containing 1" Q8N6N6 17 21238870-21253410 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.1" "Cell type enhanced" "Detected in many" "Early spermatids: 48.5;Erythroid cells: 52.0;Late spermatids: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 5.2;monocytes: 1.3" "Cell line enhanced" "Detected in many" "BEWO: 22.9;SuSa: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 12: NES - Nervous system development" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (2.16e-1)" "unprognostic (9.40e-2)" "unprognostic (4.69e-2)" "unprognostic (3.17e-2)" "unprognostic (8.22e-3)" "unprognostic (3.99e-2)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (5.93e-2)" "unprognostic (6.81e-2)" "unprognostic (2.48e-2)" "unprognostic (2.51e-1)" "prognostic favorable (3.55e-6)" "unprognostic (2.18e-1)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (3.98e-2)" 14.9 5.1 5.5 2.8 5.5 19.6 7.8 6.6 5.3 4.8 6.0 7.8 4.4 7.0 4.2 4.4 4.7 5.0 12.6 4.9 4.4 7.9 4.9 6.9 3.9 6.4 5.3 4.2 7.0 9.2 2.6 6.8 4.9 6.1 2.1 3.5 7.3 7.4 40.1 7.9 4.1 4.5 5.3 8.3 7.0 6.3 5.5 4.8 10.2 19.6 3.7 5.8 3.8 4.7 1.3 2.2 2.7 3.4 11.8 10.9 22.9 3.7 4.8 2.6 4.1 6.1 1.0 0.0 5.8 5.2 4.1 1.8 1.8 1.6 1.2 1.7 6.5 0.5 1.2 1.0 10.1 0.1 2.3 16.5 3.5 3.2 2.2 7.8 5.3 5.3 3.5 0.1 3.5 1.1 0.2 1.7 6.0 0.9 0.6 3.0 2.3 0.9 4.4 1.8 0.9 5.8 2.8 0.4 4.9 50.2 1.4 1.7 3.3 1.3 1.7 1.9 0.9 4.8 2.1 1.3 1.6 1.1 2.1 0.7 1.3 1.6 0.7 0.4 0.2 0.1 0.4 0.5 0.2 0.3 0.2 0.3 5.2 0.2 0.4 0.5 0.7 0.8 5.5 5.5 6.6 5.3 4.9 4.4 6.4 5.3 4.9 5.3 5.5 4.7 4.3 6.4 4.8 1.0 1.5 0.0 0.7 0.0 0.6 3.0 4.6 6.9 10.6 8.6 1.8 5.5 0.0 6.8 7.0 2.9 0.0 3.5 48.5 8.0 4.4 3.3 3.6 52.0 1.3 0.7 3.0 4.1 1.5 17.1 1.3 2.7 5.7 4.6 2.9 1.7 1.7 3.3 0.0 8.2 0.0 62.1 10.2 3.5 0.0 2.8 4.5 2.3 2.1 2.0 1.2 4.3 2.3 15.8 4.2 3.6 6.3 5.3 0.7 3.3 13.1 3.6 3.5 0.6 6.7 1.1 0.0 10.1 3.3 1.9 1.7 2.3 NAV1 "DKFZp781D0314, FLJ12560, FLJ14203, KIAA1151, MGC14961, POMFIL3, steerin-1" ENSG00000134369 "Neuron navigator 1" Q8NEY1 1 201622885-201826969 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 169.1;Inhibitory neurons: 161.7;Oligodendrocyte precursor cells: 713.8;Oligodendrocytes: 224.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.4;myeloid DC: 2.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2.1;granulocytes: 3.4" "Cell line enhanced" "Detected in many" "TIME: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012302, HPA018127, HPA027887" Enhanced Approved Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Microtubules "CAB012302: AB_776716, HPA018127: AB_1854317, HPA027887: AB_10601040" "unprognostic (2.14e-1)" "unprognostic (1.82e-1)" "unprognostic (4.12e-2)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-1)" "unprognostic (1.79e-1)" "unprognostic (3.45e-1)" "unprognostic (9.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.68e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (3.45e-2)" "unprognostic (2.16e-1)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" 19.6 2.7 17.4 8.2 18.3 1.6 15.2 8.0 17.7 11.7 0.0 12.3 3.7 10.1 4.3 8.6 7.2 7.5 26.6 17.5 20.3 4.6 1.9 11.1 4.1 24.6 17.9 3.7 4.4 5.2 5.2 11.8 15.1 7.5 5.4 5.4 7.8 6.7 4.8 7.7 6.2 10.3 9.9 3.6 5.3 4.4 21.8 2.8 9.4 6.7 3.7 14.9 12.6 32.5 1.6 2.9 29.0 3.8 84.3 69.5 51.7 44.6 43.0 35.5 30.9 0.0 15.7 0.6 0.7 61.4 19.4 21.5 22.0 14.9 28.4 2.5 3.2 1.4 5.6 0.0 22.5 0.2 19.1 30.6 5.4 62.4 36.0 94.9 80.7 1.8 0.8 2.6 29.8 0.4 0.0 0.1 42.4 0.7 1.7 3.9 65.0 9.3 4.8 4.3 21.9 4.5 11.1 47.6 14.5 19.2 0.4 1.2 187.8 54.5 11.1 54.7 39.4 8.1 2.3 0.2 59.2 5.9 47.5 3.4 0.5 0.1 0.2 0.3 0.1 0.3 0.2 0.0 2.1 0.3 0.2 0.1 0.0 0.1 0.3 0.5 0.0 0.3 17.4 18.3 8.0 17.7 17.5 20.3 24.6 17.9 15.1 9.9 21.8 32.5 77.4 3.2 1.5 169.1 3.1 11.0 2.2 5.9 8.0 34.6 4.8 4.3 29.2 1.5 4.8 12.9 0.0 14.9 0.9 4.7 0.0 13.0 3.6 1.6 6.4 39.3 52.8 1.7 98.2 8.3 54.1 45.8 8.2 4.4 17.7 54.5 21.0 0.7 14.5 25.2 161.7 3.4 6.1 18.3 15.8 3.8 10.8 15.1 23.2 69.3 60.6 11.8 1.0 713.8 224.6 21.7 4.2 0.7 4.9 2.3 0.9 0.6 3.5 4.0 6.6 119.3 18.8 0.6 2.6 16.9 7.0 15.7 2.0 6.6 5.0 3.2 NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 676.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.1;Leydig cells: 386.8;Paneth cells: 313.2;Peritubular cells: 356.9;Prostatic glandular cells: 293.3;Proximal enterocytes: 413.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 431.7;HSkMC: 305.6;SK-MEL-30: 473.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" NA NA 8100000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" 166.3 27.7 116.1 61.4 115.2 5.7 183.3 90.6 156.0 676.6 125.7 259.3 195.0 253.9 48.3 206.8 281.5 202.6 119.1 147.1 117.1 67.2 5.8 312.0 57.3 101.7 140.7 635.9 27.1 48.3 125.3 21.6 117.0 376.0 109.3 14.5 65.4 113.5 26.6 199.1 314.1 113.0 95.0 25.8 139.9 44.5 109.5 25.3 85.9 28.4 22.4 246.5 373.8 97.3 138.8 42.9 7.2 38.5 431.7 222.7 19.7 195.5 238.6 64.1 64.7 11.8 242.6 0.2 122.2 245.7 44.8 153.4 40.8 180.1 19.6 132.9 23.0 6.8 40.5 72.4 69.4 0.5 3.1 305.6 162.0 94.6 57.6 19.1 48.7 8.0 1.4 0.4 20.6 20.4 0.4 11.7 2.9 142.3 65.2 6.4 0.1 4.7 122.5 16.6 3.1 102.2 31.2 1.2 473.8 7.1 160.2 24.3 68.9 62.4 49.7 180.0 30.3 0.9 1.1 0.8 45.4 0.6 19.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.4 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.1 116.1 115.2 90.6 156.0 147.1 117.1 101.7 140.7 117.0 95.0 109.5 97.3 150.4 3.2 2.3 0.0 2.9 174.6 237.3 22.6 107.0 35.5 41.5 32.8 43.5 55.8 11.9 36.8 6.2 1.0 5.1 395.1 3.9 43.0 2.0 15.6 55.7 84.3 54.5 3.4 0.0 7.7 2.6 241.4 39.8 10.1 13.4 80.9 47.8 1.5 54.6 6.7 0.0 244.6 12.2 2.2 76.6 13.1 386.8 6.6 60.5 0.0 5.8 13.4 0.0 0.0 0.0 97.5 313.2 356.9 1.1 293.3 413.8 19.7 24.5 10.2 131.5 14.0 142.9 1.4 7.6 61.4 202.4 1.4 29.6 15.1 220.4 206.5 NBPF4 FLJ32833 ENSG00000196427 "NBPF member 4" Q96M43 1 108223341-108244081 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.1;intestine: 1.2;testis: 3.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "breast cancer: 0.9" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.1;K-562: 10.2;Karpas-707: 3.1;MCF7: 12.6;THP-1: 3.8" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA045044: AB_2679196, HPA046411: AB_2679657, HPA047447: AB_2680051, HPA058050: " "unprognostic (6.33e-2)" "unprognostic (2.08e-1)" "unprognostic (2.18e-2)" "unprognostic (8.29e-2)" "unprognostic (2.90e-1)" "unprognostic (8.73e-2)" 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 3.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 10.2 3.1 0.0 12.6 0.0 0.0 0.6 0.0 0.0 0.0 1.7 0.6 0.0 0.0 0.2 0.0 0.0 0.1 1.4 0.0 0.1 3.8 0.0 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NBPF6 ENSG00000186086 "NBPF member 6" Q5VWK0 1 108450282-108471002 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.2;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 6 "breast cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.5;HeLa: 1.9;K-562: 11.6;SK-BR-3: 2.4;SK-MEL-30: 1.9" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA045044: AB_2679196, HPA046411: AB_2679657, HPA047447: AB_2680051, HPA058050: " "unprognostic (4.36e-2)" "unprognostic (5.87e-2)" "unprognostic (4.62e-2)" "unprognostic (2.39e-1)" "unprognostic (2.61e-1)" "unprognostic (8.02e-2)" 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.5 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 1.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.9 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Group enriched" "Detected in many" 5 "Ductal cells: 68.6;Hofbauer cells: 212.0;Kupffer cells: 137.9;Langerhans cells: 129.5;Macrophages: 194.4;monocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 26.4;HMC-1: 21.4;hTERT-HME1: 51.6;RPMI-8226: 20.0;U-2 OS: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" 29.9 5.8 2.7 76.9 3.0 191.9 7.0 3.2 14.6 9.5 4.5 10.4 8.5 4.1 1.6 7.6 8.0 23.8 5.6 2.3 3.9 3.7 12.7 74.6 17.3 6.2 4.2 2.1 4.6 2.8 2.7 39.7 6.8 2.9 12.5 0.8 6.6 3.5 3.7 15.9 12.4 20.4 4.5 78.8 5.8 2.1 12.0 11.3 3.0 11.5 16.9 24.2 5.9 7.8 26.4 0.8 0.0 0.0 0.0 0.0 0.3 1.9 2.4 3.4 1.6 0.2 0.8 3.2 4.3 0.8 0.6 14.3 0.1 19.0 3.1 16.2 0.0 0.0 7.3 6.0 0.0 2.0 21.4 0.0 4.1 3.4 51.6 2.2 0.0 0.1 0.0 5.6 5.8 0.2 0.2 1.1 0.4 1.5 1.5 7.0 2.2 20.0 0.8 0.2 0.0 0.1 0.3 0.1 0.9 1.7 2.8 9.1 1.2 0.1 50.2 0.0 4.9 0.9 1.4 0.6 0.4 10.3 0.0 199.5 489.2 1313.6 1.0 348.8 1.6 14.1 4.0 1.6 246.0 10.8 2.2 1.3 799.7 2.1 326.1 13.5 11.1 298.9 2.7 3.0 3.2 14.6 2.3 3.9 6.2 4.2 6.8 4.5 12.0 7.8 0.7 9.6 15.7 0.0 8.4 5.5 0.2 13.7 1.8 0.3 0.1 0.3 1.3 7.2 17.3 0.0 0.0 1.0 9.6 0.1 3.9 68.6 1.1 1.9 0.5 3.5 0.0 1.7 0.3 3.9 1.1 2.0 0.5 1.3 7.6 0.0 3.3 1.0 212.0 0.0 0.3 0.2 26.4 137.9 129.5 2.9 0.6 194.4 7.2 3.7 223.6 0.0 6.2 0.0 0.2 27.3 2.6 0.0 3.2 0.6 0.0 0.3 32.0 0.7 13.1 0.7 6.8 0.1 0.6 0.6 4.3 1.9 3.7 0.2 0.0 1.2 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 66.2;dendritic cells: 92.3;Hofbauer cells: 115.5;Kupffer cells: 175.1;Macrophages: 108.1;monocytes: 153.2;NK-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 112.4;HMC-1: 112.4;NB-4: 82.6;REH: 59.1;THP-1: 121.3;U-937: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Uncertain "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" 9.7 4.6 3.3 34.8 4.0 28.4 4.7 3.6 3.7 4.0 4.0 19.7 5.8 2.5 1.3 6.1 3.4 7.3 2.6 2.9 3.7 2.3 7.1 20.2 42.5 6.9 4.8 1.8 1.6 4.0 1.5 11.0 6.5 4.7 9.7 0.4 3.5 5.2 1.2 2.3 18.1 10.3 5.4 44.9 6.7 1.2 6.8 37.4 2.2 2.0 43.4 27.9 2.8 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.3 47.9 0.0 0.0 0.0 112.4 112.4 0.0 0.0 0.0 0.0 0.0 0.7 40.1 7.7 43.7 0.0 0.0 47.9 82.6 0.1 0.0 0.0 59.1 0.2 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 121.3 0.0 0.2 0.0 0.1 0.1 2.4 2.9 38.4 0.2 70.4 0.0 31.7 68.6 55.0 31.7 103.9 26.2 30.2 28.3 32.7 72.0 28.8 17.9 26.4 16.9 36.1 121.3 40.8 45.1 65.1 3.3 4.0 3.6 3.7 2.9 3.7 6.9 4.8 6.5 5.4 6.8 8.4 1.0 0.0 11.6 0.3 66.2 1.3 0.3 0.0 0.0 1.3 0.6 2.2 1.5 4.3 1.8 0.0 0.0 0.7 92.3 0.2 0.0 0.1 0.9 0.2 0.3 3.6 0.0 22.1 0.8 0.4 1.0 2.7 2.0 0.3 56.3 0.1 7.5 1.4 115.5 0.0 0.5 0.0 0.0 175.1 28.5 2.3 1.2 108.1 5.4 42.2 153.2 0.4 113.3 0.5 0.0 0.0 0.1 0.0 40.0 0.1 0.0 0.3 0.7 0.9 0.0 0.8 1.3 0.9 1.6 0.1 0.6 1.4 59.7 0.2 0.0 0.2 NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 272.0;intestine: 123.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.9;Horizontal cells: 112.7;Inhibitory neurons: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Enhanced "Plasma membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB018587: AB_649907, HPA019713: AB_1854404" "prognostic unfavorable (5.40e-4)" "unprognostic (1.57e-1)" "unprognostic (4.64e-3)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.29e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.61e-3)" "unprognostic (4.27e-1)" "unprognostic (1.21e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.71e-3)" "unprognostic (8.59e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.65e-1)" 8.3 26.2 183.3 13.4 96.0 8.4 5.1 0.0 227.7 22.6 0.0 123.6 5.2 70.7 5.7 40.6 29.3 13.9 12.6 272.0 20.8 17.6 2.8 9.5 1.9 17.0 23.4 10.8 4.9 2.3 14.5 1.7 16.6 36.1 10.1 8.5 8.1 65.1 3.1 18.3 19.8 58.6 2.3 1.2 25.1 3.1 75.5 4.2 32.8 1.9 3.8 63.8 20.8 85.8 25.6 50.8 25.9 51.9 15.9 35.3 12.3 64.3 29.6 48.2 32.0 24.3 12.8 0.1 22.8 81.6 56.5 45.2 42.5 56.3 21.5 75.3 13.0 0.1 32.3 26.5 24.4 2.2 30.2 41.2 28.0 54.7 34.4 42.9 46.2 9.9 18.8 0.3 70.8 73.1 4.9 25.6 39.6 13.7 21.2 0.1 81.5 17.3 47.4 15.9 67.9 63.9 39.5 18.7 37.7 19.4 34.8 16.2 36.7 92.9 75.4 75.5 84.1 0.1 0.1 0.2 108.7 7.1 102.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 183.3 96.0 0.0 227.7 272.0 20.8 17.0 23.4 16.6 2.3 75.5 85.8 0.5 0.0 0.0 26.1 0.1 9.7 10.5 16.6 15.4 7.7 3.0 10.0 2.9 1.5 6.3 11.0 4.2 0.1 5.3 0.8 5.9 7.9 0.4 27.8 10.5 1.0 1.2 14.7 40.9 2.9 1.6 9.1 1.1 12.4 3.8 4.4 0.7 0.5 3.7 112.7 42.5 1.0 0.0 0.6 5.8 0.9 1.2 2.5 5.4 2.8 9.8 19.2 0.0 8.0 7.8 5.3 0.1 1.5 1.3 11.0 0.2 17.3 9.7 4.3 0.0 4.2 19.0 0.0 1.9 6.0 7.0 0.5 2.6 1.2 0.5 3.3 NDFIP1 "MGC10924, N4WBP5" ENSG00000131507 "Nedd4 family interacting protein 1" Q9BT67 5 142108779-142154440 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 678.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009682 Approved "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA009682: AB_1079455" "unprognostic (2.78e-2)" "unprognostic (1.62e-1)" "unprognostic (9.26e-2)" "unprognostic (5.66e-3)" "unprognostic (4.74e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (6.95e-2)" "unprognostic (4.96e-2)" "unprognostic (5.97e-2)" "unprognostic (1.74e-2)" "unprognostic (3.28e-1)" "unprognostic (4.46e-2)" "prognostic favorable (2.39e-7)" "unprognostic (9.18e-2)" "unprognostic (2.06e-1)" "unprognostic (6.23e-2)" "unprognostic (8.76e-2)" 62.1 81.6 87.4 33.8 93.8 26.2 56.3 63.1 100.7 54.7 70.8 40.3 49.3 45.2 135.9 30.2 46.4 45.4 55.1 94.2 96.8 94.8 120.2 49.7 39.0 70.7 73.6 61.5 64.5 152.6 51.7 45.2 77.2 67.7 38.4 164.1 99.5 63.5 45.7 26.6 47.6 40.9 75.3 56.4 50.4 40.8 90.8 41.9 103.4 40.9 34.8 48.3 31.1 73.9 53.3 35.2 61.8 83.6 128.2 72.5 41.4 56.6 59.1 48.0 54.6 39.5 87.3 4.8 115.0 62.2 66.4 51.9 39.6 59.6 56.2 61.2 48.8 69.2 30.8 28.7 55.8 38.3 23.9 55.8 55.3 33.8 43.6 68.4 55.9 54.0 23.4 83.3 60.1 27.4 42.9 12.0 33.2 52.0 33.4 16.1 34.2 122.1 119.1 56.0 65.0 67.3 61.9 91.7 88.3 46.0 64.7 37.6 64.5 58.7 22.1 48.0 56.8 53.6 65.8 22.0 62.1 24.9 45.6 70.4 32.1 26.4 22.9 39.9 29.2 12.8 40.6 28.2 37.0 10.4 80.9 63.9 19.5 23.5 40.1 11.2 50.6 62.4 87.4 93.8 63.1 100.7 94.2 96.8 70.7 73.6 77.2 75.3 90.8 73.9 100.3 57.7 62.6 74.7 76.4 111.5 176.4 133.4 82.0 196.4 134.3 68.5 70.0 143.0 101.4 154.5 141.8 146.9 94.0 98.0 140.8 207.4 20.2 69.5 91.5 103.7 137.6 184.9 189.5 145.3 263.8 164.1 62.7 118.2 60.2 365.2 116.0 169.8 154.1 318.0 184.9 81.9 177.0 205.9 154.9 15.4 116.5 137.0 170.7 69.3 176.1 300.6 87.6 114.1 125.4 179.8 100.5 156.9 107.6 262.6 198.5 173.0 67.7 322.9 131.5 74.3 149.3 26.6 33.2 71.1 101.3 191.5 156.4 678.1 83.3 256.2 NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 236.4;Peritubular cells: 207.6;Theca cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 55.0;ASC diff: 52.9;HSkMC: 71.3;NTERA-2: 44.0;SuSa: 57.4;U-2 OS: 80.4;U-266/70: 51.7;U-266/84: 51.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" 46.8 49.4 43.3 11.1 40.5 1.2 35.1 26.0 39.7 70.5 30.4 35.9 11.1 63.7 24.0 16.8 47.2 23.8 34.6 36.7 89.6 13.0 4.5 19.6 10.9 36.0 41.3 69.8 11.8 8.7 56.3 32.6 46.2 27.3 10.7 20.8 12.7 39.3 14.7 11.9 20.8 33.5 36.7 19.1 20.3 18.5 69.6 6.8 17.4 22.4 6.6 31.4 40.4 32.3 0.1 0.0 55.0 0.0 52.9 20.1 0.1 35.4 0.0 0.8 9.6 0.0 0.0 0.0 0.1 10.6 8.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 31.8 71.3 0.0 10.2 0.0 0.0 0.0 21.7 1.2 0.0 18.0 0.0 27.6 0.1 44.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.1 0.4 0.0 0.4 0.0 57.4 9.4 0.0 0.0 2.6 80.4 0.0 0.1 51.7 51.7 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 1.5 0.0 0.0 43.3 40.5 26.0 39.7 36.7 89.6 36.0 41.3 46.2 36.7 69.6 32.3 24.1 25.6 11.0 6.8 0.3 13.0 13.8 0.3 27.9 66.0 2.3 19.8 36.8 15.7 1.4 12.9 20.9 1.9 2.9 18.5 23.5 17.9 2.5 1.4 60.8 18.7 6.7 4.2 7.8 10.7 1.4 103.1 4.1 1.1 0.0 83.9 38.9 0.2 7.3 50.5 21.8 4.3 0.0 7.6 13.3 8.6 236.4 2.8 39.2 9.4 0.7 88.7 0.0 9.5 16.4 4.5 2.6 207.6 0.0 6.9 8.1 1.1 4.1 51.0 98.6 91.4 94.0 28.5 21.8 13.4 8.2 2.5 1.4 121.8 7.1 4.1 NDOR1 "bA350O14.9, CIAE1, NR1" ENSG00000188566 "NADPH dependent diflavin oxidoreductase 1" Q9UHB4 9 137205685-137217009 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.4;Oligodendrocytes: 10.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024504 Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Intermediate filaments" "HPA024504: AB_1854338" "unprognostic (1.67e-1)" "unprognostic (1.44e-2)" "unprognostic (3.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (5.89e-3)" "unprognostic (5.99e-2)" "unprognostic (9.30e-2)" "unprognostic (3.00e-1)" "unprognostic (2.61e-3)" "unprognostic (1.14e-1)" "unprognostic (1.07e-1)" "unprognostic (4.69e-3)" "unprognostic (2.05e-1)" "unprognostic (4.30e-2)" "unprognostic (6.74e-3)" 6.5 8.2 8.7 9.8 9.6 17.2 6.9 7.9 12.5 8.1 5.4 8.4 9.6 7.8 2.0 8.3 7.9 4.6 6.6 8.3 7.1 9.0 7.1 8.6 11.5 10.7 9.0 7.0 8.9 4.0 8.2 4.0 10.2 9.6 2.9 3.9 8.6 5.2 4.0 9.5 10.6 3.7 7.9 14.2 8.7 10.5 9.9 8.9 10.1 1.5 5.4 7.8 7.2 12.9 14.2 21.2 13.8 21.8 5.7 5.6 42.7 20.4 9.1 19.1 13.0 21.6 16.3 19.9 15.6 7.7 15.3 52.1 10.0 14.3 3.8 25.9 16.3 17.6 59.7 11.6 9.6 19.9 36.2 7.8 9.7 21.6 7.9 5.3 8.9 25.9 29.2 20.6 7.0 25.8 21.0 35.8 22.5 12.9 26.0 38.0 16.5 28.2 6.0 12.4 17.6 17.5 16.8 17.0 10.6 6.1 27.2 22.8 12.0 35.3 22.9 41.7 23.2 12.5 26.8 20.7 15.4 18.1 20.7 1.1 2.1 3.1 1.3 2.2 1.1 0.5 1.2 1.2 1.7 1.0 0.6 0.6 2.9 0.7 1.7 1.1 1.8 1.5 8.7 9.6 7.9 12.5 8.3 7.1 10.7 9.0 10.2 7.9 9.9 12.9 1.4 0.0 2.6 13.4 3.9 0.5 0.7 1.0 5.2 0.4 1.5 1.3 1.6 1.5 1.6 3.7 0.0 4.5 1.4 3.3 1.9 1.1 0.8 1.3 1.9 1.8 2.4 1.3 8.6 1.1 3.5 1.6 5.1 2.1 1.3 2.0 1.1 0.8 2.5 0.0 7.5 1.9 2.0 3.2 1.3 1.1 0.6 2.7 1.8 6.5 5.4 0.1 5.2 3.5 10.5 1.6 1.5 0.4 6.9 0.7 2.6 1.2 0.3 0.9 0.0 0.9 1.4 1.9 1.2 3.2 0.3 3.7 3.8 1.6 2.2 0.8 NDUFA4L2 "COXFA4L2, FLJ26118, NUOMS" ENSG00000185633 "NDUFA4 mitochondrial complex associated like 2" Q9NRX3 12 57234903-57240715 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 304.9" "Group enriched" "Detected in many" 4 "Muller glia cells: 627.0;Sertoli cells: 1130.7;Smooth muscle cells: 525.6" "Cancer enriched" "Detected in all" 5 "renal cancer: 356.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "AN3-CA: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-3)" "unprognostic (3.23e-3)" "unprognostic (5.06e-2)" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (3.53e-1)" "unprognostic (6.67e-2)" "unprognostic (5.79e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.10e-3)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (2.74e-2)" 85.6 14.0 41.6 6.8 40.1 0.2 55.1 41.4 61.5 109.3 36.8 17.4 5.8 20.7 2.4 304.9 15.5 17.1 180.1 40.3 41.1 47.6 20.9 62.6 5.8 43.0 42.7 14.0 14.5 12.1 30.9 71.7 48.8 27.3 1.9 29.4 55.8 9.8 43.8 206.9 14.2 7.5 38.9 74.1 18.0 8.7 43.5 3.2 54.5 29.2 4.8 27.7 183.5 45.4 0.9 1.3 0.3 133.9 5.4 3.1 0.4 2.1 1.5 0.6 1.3 0.0 1.5 5.5 5.6 2.1 0.1 1.2 0.7 1.0 0.0 3.0 0.2 0.6 0.3 0.1 18.6 4.1 2.0 12.0 2.5 0.2 4.7 0.9 0.0 7.6 0.5 7.2 0.4 2.7 1.1 0.2 0.3 0.6 2.4 2.1 1.0 11.0 0.1 0.1 7.1 2.5 0.2 0.3 4.7 0.1 1.5 14.5 0.6 1.2 0.1 1.1 0.7 10.0 3.5 2.5 4.9 9.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 41.6 40.1 41.4 61.5 40.3 41.1 43.0 42.7 48.8 38.9 43.5 45.4 156.0 0.0 0.5 2.6 2.6 151.2 0.9 89.2 6.8 30.6 2.6 5.8 1.2 0.0 24.8 0.0 18.8 1.0 0.9 0.1 0.0 1.6 1.7 0.4 3.0 91.8 0.0 0.0 2.2 0.0 1.5 21.5 4.6 0.3 8.9 0.1 2.9 1.3 1.9 11.8 3.0 0.2 54.9 0.0 28.9 3.0 3.1 2.0 30.2 18.7 1.0 627.0 0.0 0.5 0.4 4.7 0.0 2.2 1.4 2.0 0.1 0.3 6.2 25.7 1130.7 13.0 525.6 12.3 5.5 20.3 161.4 1.1 1.9 2.5 0.2 1.4 NDUFAF6 "C8orf38, MGC40214" ENSG00000156170 "NADH:ubiquinone oxidoreductase complex assembly factor 6" Q330K2 8 94895767-95116455 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047148, HPA050545" Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA047148: AB_2679954, HPA050545: AB_2681166" "unprognostic (1.97e-3)" "unprognostic (1.62e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (8.73e-2)" "unprognostic (3.45e-2)" "unprognostic (7.62e-3)" "unprognostic (2.52e-2)" "unprognostic (9.61e-2)" "unprognostic (3.85e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-3)" "unprognostic (9.44e-2)" "unprognostic (1.57e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-3)" 4.7 3.1 6.9 4.1 7.7 5.5 5.3 8.8 8.1 1.9 5.1 4.4 2.1 3.2 5.7 4.3 4.2 1.9 8.8 6.4 7.8 4.4 10.9 2.6 4.9 6.9 7.6 3.9 3.1 3.5 2.6 3.6 7.3 3.5 5.5 7.4 2.2 3.4 14.6 5.6 3.0 3.2 6.7 3.1 4.3 4.0 7.6 4.7 6.3 13.8 5.2 2.5 1.7 8.9 7.7 4.5 5.4 5.1 3.5 4.3 11.1 8.0 5.0 6.6 4.8 3.6 3.7 14.8 5.3 3.7 2.0 6.3 7.8 5.4 4.9 3.7 15.1 13.7 10.0 6.7 5.4 5.1 6.9 6.5 9.0 3.8 6.1 3.0 3.8 12.1 9.9 8.0 8.0 6.8 13.0 16.5 5.9 10.0 10.6 8.6 4.3 11.3 6.1 7.3 10.1 5.5 4.1 2.5 10.8 6.5 10.1 4.2 4.8 4.7 3.7 3.7 5.8 10.7 8.5 12.4 3.9 13.5 2.7 1.9 1.8 3.0 2.3 1.1 2.9 5.8 3.2 2.2 2.4 5.4 3.1 2.3 0.9 2.9 2.2 2.1 2.9 1.9 6.9 7.7 8.8 8.1 6.4 7.8 6.9 7.6 7.3 6.7 7.6 8.9 23.4 12.8 15.9 35.3 23.6 9.7 10.1 21.5 19.4 22.7 25.7 27.4 32.0 28.6 21.2 12.9 16.7 24.0 14.3 18.5 43.0 15.8 28.5 13.5 9.1 14.8 12.5 23.3 31.8 34.7 30.2 9.4 10.7 9.8 31.8 21.5 12.1 28.3 22.6 25.2 37.0 15.3 24.4 7.3 5.6 8.1 10.5 10.1 14.2 33.7 12.0 25.6 6.2 43.2 58.3 19.3 18.2 13.9 53.1 11.2 23.2 38.2 24.7 23.6 13.1 11.9 21.4 28.4 43.9 17.9 11.9 10.9 13.0 16.5 19.4 9.5 NDUFC2 "B14.5b, HLC-1" ENSG00000151366 "NADH:ubiquinone oxidoreductase subunit C2" O95298 11 78068297-78079862 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" "unprognostic (7.32e-2)" "unprognostic (5.91e-3)" "unprognostic (4.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.94e-1)" "unprognostic (8.97e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-3)" "unprognostic (4.75e-3)" "unprognostic (3.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "prognostic favorable (5.00e-5)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (3.61e-3)" 202.3 278.0 118.8 84.5 126.1 126.1 143.0 128.7 150.7 103.0 125.6 143.6 218.4 125.3 68.4 142.6 120.2 108.6 240.7 129.0 145.8 151.1 286.8 100.0 109.1 121.6 117.1 96.2 168.8 186.1 133.5 74.8 124.2 88.7 66.1 59.8 275.1 83.2 487.6 121.9 194.3 63.6 136.8 96.2 130.0 103.0 126.1 73.5 207.0 254.0 62.8 97.1 100.1 136.3 287.6 342.2 183.3 118.8 168.3 105.6 227.2 335.7 190.9 252.4 179.9 910.4 311.8 166.3 583.3 155.8 210.2 293.1 136.1 190.9 99.5 318.8 386.7 183.8 337.4 727.9 270.9 409.7 164.2 147.9 177.8 195.6 75.2 156.0 172.9 158.8 365.3 278.4 137.9 478.7 254.5 722.4 212.4 670.4 415.6 224.5 352.5 570.5 196.4 420.7 261.2 229.0 235.0 499.5 182.3 158.8 391.4 328.2 241.0 256.4 314.9 611.8 297.9 251.5 541.9 400.4 146.4 236.6 251.0 374.5 337.6 354.0 150.1 293.0 138.3 230.8 172.4 163.4 363.5 212.1 144.5 159.8 102.2 225.4 243.0 290.4 202.7 410.9 118.8 126.1 128.7 150.7 129.0 145.8 121.6 117.1 124.2 136.8 126.1 136.3 256.6 166.7 194.7 0.0 106.4 95.5 166.1 443.7 40.5 145.8 346.2 414.0 240.9 243.1 288.2 391.8 66.7 408.8 166.4 206.3 305.2 395.6 311.8 413.8 129.3 183.7 167.9 106.5 0.0 431.5 392.8 165.7 43.3 241.7 153.2 158.1 184.9 856.9 346.2 90.9 0.0 317.9 429.3 174.5 110.7 84.7 215.6 129.4 245.5 0.0 246.7 310.0 175.1 0.0 0.0 456.5 329.1 201.6 102.5 239.0 461.8 454.6 300.0 131.6 236.7 154.5 222.7 384.4 162.1 67.5 114.4 387.1 109.9 226.3 373.2 215.6 NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159509 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 181.7;skeletal muscle: 221.6;tongue: 225.2" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Enhanced Supported Mitochondria NA NA 48000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB070844: , HPA064605: AB_2685297" "prognostic unfavorable (3.85e-4)" "unprognostic (1.76e-1)" "unprognostic (9.22e-3)" "unprognostic (5.01e-2)" "unprognostic (8.63e-3)" "unprognostic (3.75e-1)" "unprognostic (3.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.47e-12)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" "unprognostic (4.73e-2)" 27.1 61.6 8.3 13.3 10.8 13.2 23.8 14.9 16.1 19.5 39.7 35.3 29.9 19.3 10.8 36.2 16.3 10.5 181.7 10.7 13.7 48.0 51.8 18.3 12.6 10.1 10.1 14.6 19.2 47.2 20.2 14.4 11.7 15.8 30.0 24.4 27.7 15.6 221.6 26.6 26.1 16.4 9.2 16.8 37.1 20.8 14.2 15.6 17.9 225.2 16.9 22.4 22.4 12.5 28.3 27.6 39.2 28.6 35.8 28.9 45.4 40.4 43.4 66.0 47.6 72.0 32.1 31.7 34.8 50.8 65.5 38.5 52.9 39.2 58.2 14.6 24.9 63.5 65.1 64.9 37.0 46.2 27.5 35.3 22.5 51.9 40.4 29.6 52.3 39.3 69.8 31.1 43.6 35.2 38.5 30.7 36.5 47.2 48.6 38.3 54.7 55.1 54.7 50.7 38.1 29.8 46.7 45.1 67.1 53.3 39.8 44.2 40.1 36.2 32.0 35.8 39.1 29.8 38.4 46.9 36.3 37.5 37.8 14.1 12.9 15.7 12.4 15.2 9.6 9.6 10.8 11.8 14.7 9.0 9.6 11.1 9.2 12.5 22.5 7.8 15.9 9.5 8.3 10.8 14.9 16.1 10.7 13.7 10.1 10.1 11.7 9.2 14.2 12.5 32.4 60.9 33.0 45.1 23.8 16.2 21.7 40.8 30.1 97.1 19.3 14.0 582.5 48.6 42.8 38.6 120.9 48.4 18.8 74.5 93.9 44.2 14.5 49.8 49.8 36.6 51.0 42.0 67.8 28.2 33.7 42.3 48.4 54.5 37.3 42.3 29.3 94.5 34.0 117.8 72.8 47.9 54.9 31.2 10.7 7.0 33.5 27.7 30.2 28.1 37.2 62.7 27.8 45.2 41.6 32.1 46.4 44.8 31.0 19.9 77.8 102.3 53.5 81.5 32.9 55.2 60.8 58.2 49.5 40.8 16.6 52.5 23.7 71.5 69.9 26.6 NDUFV3 CI-10k ENSG00000160194 "NADH:ubiquinone oxidoreductase subunit V3" P56181 21 42879644-42913304 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 770.8;Early spermatids: 502.9;Late spermatids: 1712.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019791, HPA020463, HPA030427, CAB034142" Enhanced Enhanced Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "CAB034142: AB_2298212, HPA019791: AB_1854357, HPA020463: AB_1854358, HPA030427: AB_10603024" "unprognostic (1.62e-1)" "unprognostic (2.17e-3)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.11e-2)" "unprognostic (4.69e-1)" "unprognostic (2.97e-2)" "unprognostic (1.05e-1)" "unprognostic (3.13e-1)" "unprognostic (3.85e-3)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (6.56e-2)" "unprognostic (9.30e-3)" "unprognostic (2.14e-1)" "unprognostic (1.94e-1)" 20.5 18.1 9.2 3.2 9.3 6.8 17.5 9.5 8.9 16.6 7.5 24.2 5.1 19.1 7.9 18.9 17.3 2.4 47.2 7.6 8.0 18.0 26.9 13.7 3.1 9.5 9.7 19.1 24.0 7.5 16.6 3.0 9.2 16.3 4.1 7.7 17.3 4.0 88.0 19.0 16.1 3.6 8.4 17.0 19.7 20.9 9.2 2.5 14.9 21.1 3.2 18.4 15.9 10.1 3.3 4.9 9.1 8.1 7.9 5.0 10.4 6.6 4.2 5.2 3.4 10.6 6.2 4.9 4.2 4.1 11.7 5.4 8.8 8.1 3.5 2.8 7.4 20.1 8.7 9.0 9.4 6.0 7.8 8.0 8.2 6.9 12.0 4.2 6.1 5.6 13.5 7.3 5.6 10.5 3.7 6.2 10.2 15.7 6.9 4.6 5.3 12.3 9.5 7.5 5.8 4.7 9.0 10.3 4.8 4.4 10.2 4.6 8.9 3.2 3.0 4.4 4.8 12.1 7.1 3.5 5.7 7.7 4.6 3.1 5.7 3.8 2.8 7.1 2.4 2.9 2.4 2.2 5.0 3.5 2.9 2.8 3.3 4.4 6.6 4.4 2.7 2.8 9.2 9.3 9.5 8.9 7.6 8.0 9.5 9.7 9.2 8.4 9.2 10.1 42.8 54.5 46.7 14.4 36.5 19.9 53.7 97.7 24.5 81.2 64.9 65.7 770.8 92.9 58.6 90.1 68.8 57.5 32.5 89.3 230.9 86.5 502.9 84.5 64.9 48.1 78.3 112.4 19.4 101.5 59.5 57.2 55.5 56.9 31.6 45.5 68.2 334.5 114.4 57.2 22.1 114.8 87.5 88.3 38.1 1712.0 66.5 62.3 37.4 17.8 86.4 88.7 49.4 15.6 19.5 98.6 80.9 62.4 39.0 109.3 176.4 372.6 85.9 104.7 72.3 54.0 66.1 243.5 77.1 50.0 23.4 89.9 29.9 83.8 95.4 65.3 NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 128.8;skin 1: 134.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 12.1;Breast myoepithelial cells: 27.3;Exocrine glandular cells: 12.3;Granulosa cells: 68.7;Pancreatic endocrine cells: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 229.2;hTCEpi: 139.2;RT4: 157.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" NA NA 180000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "CAB016135: AB_626865, HPA026846: AB_1846226" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.25e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (3.42e-1)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.59e-3)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.62e-2)" 4.4 4.0 14.8 4.7 25.6 24.3 8.2 17.4 32.3 14.0 0.0 12.4 16.6 3.4 2.3 128.8 4.0 3.4 8.1 30.5 15.3 5.1 4.3 3.4 2.1 23.8 26.5 2.3 18.8 2.7 7.8 7.3 18.4 12.8 12.9 18.5 18.0 6.2 1.9 134.4 12.0 4.5 16.3 3.3 4.6 1.3 26.9 6.7 2.2 1.6 27.9 28.9 36.8 38.8 16.6 13.6 12.6 18.2 6.5 2.1 88.2 6.6 6.1 5.4 3.8 28.8 55.2 21.8 26.1 7.6 10.9 229.2 32.5 117.6 2.4 51.8 4.9 3.0 4.4 13.2 2.6 14.9 35.4 2.0 139.2 17.1 62.5 2.1 16.3 6.2 0.6 113.2 7.2 42.7 0.3 9.0 41.6 55.3 18.7 1.2 75.7 26.3 5.1 157.4 30.6 68.6 22.1 57.4 1.8 18.8 52.3 2.2 9.0 4.8 17.6 39.2 5.9 20.6 28.0 0.2 1.7 11.9 11.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 1.6 0.0 0.0 14.8 25.6 17.4 32.3 30.5 15.3 23.8 26.5 18.4 16.3 26.9 38.8 4.2 0.0 3.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 12.1 27.3 0.0 0.0 4.3 1.8 0.0 4.1 4.1 0.0 0.0 8.7 0.0 4.6 3.2 1.3 0.0 0.0 0.0 12.3 1.3 2.1 0.0 10.9 0.0 68.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.5 0.0 0.0 1.9 0.0 0.0 3.3 1.5 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 8.9 1.3 1.7 0.0 0.0 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 82.8;Distal enterocytes: 82.5;Endothelial cells: 53.8;Leydig cells: 54.7;Paneth cells: 42.1;Proximal enterocytes: 53.4;Smooth muscle cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 43.7;T-47d: 20.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 46: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 25.0 16.0 8.4 5.2 10.3 2.0 21.1 2.3 24.1 18.3 3.4 28.4 6.9 24.7 24.1 13.5 22.0 11.7 32.2 17.1 6.9 11.0 6.0 12.6 3.7 3.5 4.6 14.7 5.3 3.2 8.2 6.1 3.8 17.6 13.7 0.3 6.6 32.1 14.0 18.1 17.6 20.4 3.6 0.7 7.7 4.3 6.3 5.9 10.3 16.0 3.9 25.7 17.3 6.5 7.2 3.7 2.0 8.9 0.6 0.3 0.1 8.0 3.5 4.1 6.0 13.7 3.2 0.0 2.1 5.2 5.0 2.1 0.7 3.6 2.8 13.2 0.5 9.8 13.3 0.1 0.6 0.0 2.9 0.0 15.1 0.9 4.1 1.2 0.6 1.4 0.0 3.0 8.9 8.0 2.3 0.2 1.3 3.1 0.3 43.7 9.4 1.4 0.1 1.6 1.6 8.9 7.6 11.9 0.3 3.5 20.0 1.5 1.3 3.1 18.1 2.2 5.1 1.2 0.4 0.0 9.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.3 2.3 24.1 17.1 6.9 3.5 4.6 3.8 3.6 6.3 6.5 82.8 0.0 1.9 0.3 0.6 4.8 0.7 3.0 0.6 0.6 1.5 1.3 9.3 1.5 4.8 0.0 0.0 0.3 0.4 82.5 0.0 0.7 2.6 1.9 2.5 53.8 13.9 11.4 5.2 0.7 0.2 10.3 2.0 0.6 0.0 4.9 30.4 0.3 0.3 0.0 1.0 10.2 2.0 1.9 2.6 6.6 54.7 2.2 7.2 4.7 0.7 0.7 0.0 5.0 13.0 4.5 42.1 12.4 0.1 1.9 53.4 0.8 12.8 0.3 26.3 11.6 58.8 2.5 3.4 7.7 5.4 0.1 0.7 2.5 20.0 1.2 NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "granulocytes: 11.4;Hofbauer cells: 17.0;Kupffer cells: 53.9;Macrophages: 27.2;monocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cell line enriched" "Detected in some" 4 "THP-1: 37.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" 6.3 1.9 1.5 12.4 1.9 30.9 1.1 1.5 2.2 1.8 2.0 1.5 1.3 0.6 0.6 1.3 2.0 2.3 1.3 1.8 2.4 1.2 2.3 7.5 5.5 3.1 2.2 0.3 0.8 0.3 0.6 2.9 2.9 0.9 1.2 0.1 0.8 1.4 0.4 1.4 2.3 2.9 2.3 19.9 1.1 0.7 2.9 2.1 0.7 1.5 2.1 3.1 0.7 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 5.8 0.0 0.0 0.1 0.0 0.4 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.3 48.2 2.8 0.1 32.5 0.2 0.0 0.1 0.0 16.5 0.1 0.0 0.0 90.4 0.0 31.1 0.3 0.0 25.4 1.5 1.9 1.5 2.2 1.8 2.4 3.1 2.2 2.9 2.3 2.9 3.0 0.4 0.0 3.7 0.0 0.5 0.9 0.7 0.9 0.6 0.2 0.4 0.0 0.6 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.8 0.4 0.2 0.5 1.2 0.0 0.7 0.2 0.1 0.5 0.0 0.3 11.4 0.0 0.7 0.6 17.0 0.0 0.6 0.0 0.0 53.9 8.2 5.6 0.3 27.2 0.0 8.4 44.6 0.0 0.0 2.0 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.5 0.5 0.8 0.7 0.0 1.0 0.3 1.3 0.4 0.0 0.5 NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Endometrial stromal cells: 28.3;Fibroblasts: 22.8;Sertoli cells: 26.3;Smooth muscle cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;BJ hTERT+: 49.5;hTERT-RPE1: 42.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" 48.4 54.9 9.1 6.0 9.4 0.6 47.2 8.6 10.5 126.0 9.0 71.9 4.5 82.1 13.7 22.2 82.6 17.8 30.2 9.0 9.3 35.5 5.6 30.2 4.8 10.3 9.4 142.7 13.8 9.0 37.9 18.2 8.8 51.5 5.0 2.8 20.5 16.2 9.0 25.0 29.9 18.8 8.2 17.7 35.5 42.7 9.7 1.7 50.4 2.5 3.6 66.2 65.9 8.5 0.0 0.1 17.8 0.0 25.4 36.8 0.1 17.3 49.5 23.0 20.0 0.0 14.6 14.9 0.5 25.0 1.6 0.0 7.1 0.3 13.9 0.0 0.6 11.3 20.6 0.0 12.3 0.0 0.0 26.8 0.3 13.9 0.1 42.5 18.2 4.7 3.7 0.0 4.5 0.8 0.0 1.7 2.3 1.0 0.1 1.1 1.6 2.0 0.0 0.2 2.9 11.9 0.0 3.3 5.7 8.7 10.3 4.5 10.3 21.3 4.4 20.5 0.0 10.4 1.6 11.0 4.4 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.4 8.6 10.5 9.0 9.3 10.3 9.4 8.8 8.2 9.7 8.5 4.1 3.2 8.1 58.8 1.1 4.5 0.9 1.9 0.6 1.3 3.3 2.8 7.8 0.0 4.8 0.0 0.0 0.6 0.0 0.8 0.0 2.8 4.4 2.5 28.3 4.6 7.7 0.0 0.1 0.2 0.6 22.8 3.6 6.4 0.0 4.1 1.4 0.2 0.6 0.0 0.2 3.4 10.2 0.0 6.8 6.5 17.4 0.4 7.2 13.1 0.0 7.6 0.0 1.0 0.2 0.6 0.3 7.5 0.2 0.8 0.4 0.2 2.1 1.5 26.3 4.3 27.1 12.5 2.9 1.0 3.4 0.5 0.9 6.0 1.6 2.3 NFU1 "CGI-33, HIRIP5, NifU, NIFUC" ENSG00000169599 "NFU1 iron-sulfur cluster scaffold" Q9UMS0 2 69396113-69437628 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 189.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035826 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA035826: AB_2674803" "unprognostic (4.49e-3)" "unprognostic (5.62e-2)" "unprognostic (5.40e-2)" "unprognostic (1.84e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-3)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-1)" "unprognostic (2.21e-3)" "unprognostic (2.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.87e-1)" 66.8 46.3 36.8 22.5 39.3 33.4 56.8 40.0 56.0 35.6 37.4 51.4 31.3 35.9 51.9 27.9 35.3 29.0 110.4 37.5 40.9 64.2 39.5 31.8 30.0 40.2 39.7 38.0 39.9 43.3 45.1 38.1 41.4 34.3 38.1 56.9 41.2 36.5 140.8 22.3 33.4 33.1 39.9 31.0 43.8 34.6 39.0 22.8 41.9 120.2 29.5 44.8 31.1 42.0 59.3 59.2 56.1 55.5 70.4 75.4 61.6 61.0 62.0 59.0 47.8 114.7 56.9 42.4 30.0 57.0 85.6 25.4 63.7 64.2 79.5 77.8 62.3 43.5 38.2 102.0 70.1 73.7 59.2 58.4 37.2 67.5 41.2 56.0 65.6 41.8 80.1 41.8 99.1 11.9 39.1 119.0 53.9 62.9 64.3 42.6 85.5 15.6 83.5 57.6 45.9 34.3 35.2 32.2 92.5 57.6 40.8 49.4 67.8 71.3 47.1 52.2 80.8 53.8 48.4 23.1 54.2 74.7 55.8 20.2 13.6 25.5 15.9 18.6 15.6 21.7 16.3 18.9 12.4 25.1 16.9 18.6 4.3 18.0 28.5 25.0 24.8 12.3 36.8 39.3 40.0 56.0 37.5 40.9 40.2 39.7 41.4 39.9 39.0 42.0 30.6 32.1 22.5 9.8 37.0 16.2 35.9 96.7 21.1 23.9 33.2 29.6 92.3 37.1 42.6 38.6 12.5 113.9 34.1 34.6 189.8 56.9 111.0 40.0 27.1 34.9 53.3 25.7 15.4 60.9 70.5 30.9 20.4 25.3 58.3 21.6 33.5 32.0 82.6 18.5 18.8 47.7 57.0 35.8 24.0 34.2 34.8 30.2 39.2 10.3 66.8 55.6 46.4 21.1 27.1 50.3 39.7 36.9 25.4 28.8 56.3 163.0 58.9 33.4 46.0 36.9 44.1 82.9 60.4 18.8 14.9 61.3 33.3 42.7 46.3 35.4 NIBAN3 "BCNP1, FAM129C, FLJ39802" ENSG00000167483 "Niban apoptosis regulator 3" Q86XR2 19 17523301-17553839 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "bone marrow: 15.4;intestine: 16.6;lymphoid tissue: 34.7" "Cell type enriched" "Detected in some" 8 "B-cells: 11.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 31.9;naive B-cell: 52.1;plasmacytoid DC: 110.7" "Group enriched" "Detected in many" 476 "B-cells: 52.1;dendritic cells: 110.7" "Group enriched" "Detected in some" 19 "Daudi: 50.1;REH: 23.8;U-698: 33.2" "Not detected" "Not detected" HPA043277 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA043277: AB_10794391" "unprognostic (6.55e-5)" "unprognostic (3.03e-7)" "unprognostic (3.40e-1)" "unprognostic (1.62e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-4)" "unprognostic (3.79e-3)" "unprognostic (1.69e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-1)" "unprognostic (9.47e-4)" "unprognostic (8.42e-2)" "unprognostic (5.51e-5)" "unprognostic (3.39e-1)" "unprognostic (9.03e-3)" "unprognostic (6.08e-2)" "unprognostic (7.56e-3)" 0.4 0.0 0.0 10.7 0.1 15.4 0.1 0.0 0.2 0.1 0.0 0.8 0.0 0.1 0.0 0.4 0.1 1.0 0.1 0.0 0.0 0.5 0.3 0.4 26.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.0 16.6 0.0 0.0 34.7 0.7 0.5 0.0 1.8 0.6 0.0 12.2 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 0.0 0.0 0.0 52.1 0.0 0.1 0.0 0.0 0.0 110.7 0.0 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NKAPL "bA424I5.1, C6orf194" ENSG00000189134 "NFKB activating protein like" Q5M9Q1 6 28259297-28260958 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.6;testis: 32.3" "Group enriched" "Detected in many" 4 "Early spermatids: 401.2;Spermatocytes: 307.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 3.2;BJ: 1.4;fHDF/TERT166: 2.2;HHSteC: 4.6;HSkMC: 3.0;HUVEC TERT2: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.93e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (9.73e-2)" "unprognostic (2.47e-1)" "unprognostic (7.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.88e-2)" "unprognostic (3.84e-3)" "unprognostic (5.78e-2)" "unprognostic (5.83e-5)" "unprognostic (6.65e-3)" "unprognostic (2.38e-1)" "unprognostic (2.08e-2)" "unprognostic (2.47e-2)" 1.9 1.3 5.9 0.7 5.9 0.2 1.5 6.4 9.0 0.8 5.0 2.2 0.2 1.1 1.1 0.9 0.7 0.7 5.0 5.6 6.1 2.0 0.8 0.7 0.7 6.8 6.3 2.0 1.5 0.3 2.1 0.8 6.7 1.4 0.4 12.6 1.6 2.5 5.6 0.7 0.7 1.4 6.1 1.3 1.1 32.3 6.4 0.5 1.0 4.0 0.5 2.0 0.5 6.6 0.0 0.0 0.0 0.0 3.2 0.9 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 3.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 1.6 0.1 1.3 0.3 1.2 0.0 0.2 0.9 0.1 0.2 0.2 2.2 0.3 1.0 2.5 0.0 0.2 5.9 5.9 6.4 9.0 5.6 6.1 6.8 6.3 6.7 6.1 6.4 6.6 4.2 0.0 0.0 2.6 1.1 1.0 1.6 2.5 0.0 29.5 1.8 3.7 13.0 1.5 2.6 1.8 43.8 0.1 4.7 0.0 9.8 2.1 401.2 0.4 2.5 4.8 0.0 0.0 3.3 0.7 0.0 4.1 0.0 0.2 0.0 1.4 3.9 3.5 3.2 33.7 3.3 0.1 10.2 5.1 3.1 49.2 5.6 2.7 5.4 1.9 3.6 15.7 2.1 1.0 2.1 1.4 0.0 6.4 0.4 1.6 0.1 4.1 1.3 77.4 0.0 3.1 5.7 307.1 28.1 1.1 0.9 0.3 1.9 3.2 0.1 0.6 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5;lymphoid tissue: 13.6" "Cell type enhanced" "Detected in many" "B-cells: 10.3;dendritic cells: 18.8;NK-cells: 37.0;T-cells: 23.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 8.8;HEL: 8.7;HL-60: 18.6;HMC-1: 9.0;JURKAT: 9.2;NB-4: 19.7;U-698: 28.9;U-937: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Vesicles, Centriolar satellite" "HPA048062: AB_2680242" "unprognostic (4.93e-3)" "unprognostic (3.84e-4)" "unprognostic (7.61e-4)" "unprognostic (4.94e-7)" "unprognostic (9.56e-2)" "unprognostic (3.76e-5)" "unprognostic (1.86e-3)" "unprognostic (6.70e-3)" "unprognostic (2.66e-2)" "unprognostic (7.02e-2)" "unprognostic (3.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.40e-2)" "unprognostic (5.13e-2)" "unprognostic (7.15e-3)" "unprognostic (4.54e-2)" "unprognostic (2.08e-2)" 1.0 0.8 0.3 7.8 0.4 4.1 0.7 0.8 0.7 0.9 1.0 1.5 1.7 0.9 0.4 0.8 1.2 1.4 1.5 0.3 0.0 1.3 1.1 2.4 13.6 0.3 0.3 0.7 0.5 0.2 0.9 0.9 0.1 1.1 1.2 1.1 1.1 0.3 1.1 0.5 6.5 0.5 0.0 11.8 2.1 0.9 0.3 11.3 1.5 0.9 11.1 1.5 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 8.8 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.2 8.7 0.1 0.0 0.0 18.6 9.0 0.0 0.0 0.0 0.0 0.5 0.2 9.2 0.2 0.0 0.0 0.4 7.7 19.7 0.0 0.0 0.1 5.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 0.1 4.9 0.5 0.3 0.1 0.2 0.1 0.4 0.2 28.9 0.2 13.6 0.1 2.9 0.0 0.0 2.3 0.0 2.1 0.8 1.7 2.2 0.0 0.6 1.4 1.5 0.0 2.6 0.0 0.0 2.0 2.1 0.3 0.4 0.8 0.7 0.3 0.0 0.3 0.3 0.1 0.0 0.3 0.1 1.7 3.2 0.0 1.0 10.3 0.0 0.3 0.0 0.0 1.6 0.4 0.3 4.6 1.5 0.6 1.8 4.2 0.0 18.8 0.0 0.0 0.0 4.0 1.3 0.8 2.3 0.0 6.5 3.8 0.0 0.0 0.5 1.5 0.7 2.5 0.2 3.9 0.1 0.1 0.0 3.7 0.0 0.0 1.0 0.0 1.3 0.0 1.1 0.0 1.9 1.3 0.3 37.0 1.0 0.6 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.7 5.1 0.0 0.9 0.7 0.5 0.3 0.0 0.0 0.0 23.8 0.1 0.0 0.3 NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;lung: 6.2;lymphoid tissue: 11.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 11.9;Kupffer cells: 21.0;Macrophages: 14.5;Microglial cells: 10.3;monocytes: 18.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "classical monocyte: 49.3;intermediate monocyte: 56.9;myeloid DC: 32.2;neutrophil: 24.6;non-classical monocyte: 44.2" "Group enriched" "Detected in many" 32 "dendritic cells: 32.2;granulocytes: 24.6;monocytes: 56.9" "Cell line enhanced" "Detected in some" "HL-60: 3.1" "Not detected" "Not detected" "HPA006592, HPA075894" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA006592: AB_2667620, HPA075894: " "unprognostic (7.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.88e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-2)" "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (6.33e-2)" "unprognostic (6.33e-2)" "unprognostic (6.03e-6)" "unprognostic (7.42e-2)" "unprognostic (2.06e-3)" "unprognostic (2.02e-2)" "unprognostic (1.63e-1)" 3.4 1.4 0.4 8.7 0.5 8.3 0.7 0.4 0.8 0.6 0.6 0.9 0.9 0.4 0.0 0.6 0.8 1.4 1.2 0.4 0.4 0.5 1.6 6.2 2.3 0.6 0.5 0.3 0.8 0.1 0.6 2.1 0.6 0.4 0.8 0.6 0.5 0.2 1.0 0.3 1.3 2.3 0.5 11.4 0.6 0.4 0.9 0.7 0.4 0.3 1.2 2.0 0.3 0.8 0.1 0.2 0.3 0.7 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.3 0.5 0.1 0.4 0.0 3.1 0.5 0.0 0.3 0.0 1.4 0.4 0.0 0.1 0.3 0.2 0.0 0.0 0.2 1.4 0.1 0.2 0.2 0.1 0.4 0.5 0.0 0.3 0.3 0.7 0.2 0.2 1.2 0.5 0.1 1.4 0.1 0.3 0.3 0.2 0.4 0.3 0.8 1.2 0.4 1.3 0.4 0.5 49.3 5.8 0.1 56.9 0.4 0.6 0.0 0.0 32.2 1.1 0.0 0.1 24.6 0.3 44.2 0.4 0.2 18.6 0.4 0.5 0.4 0.8 0.4 0.4 0.6 0.5 0.6 0.5 0.9 0.8 0.2 0.0 1.8 1.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.7 4.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 1.1 0.0 11.9 0.0 3.3 0.0 0.0 21.0 1.0 0.0 0.0 14.5 0.0 10.3 18.4 0.0 1.0 1.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 NLRP1 "CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1" ENSG00000091592 "NLR family pyrin domain containing 1" Q9C000 17 5499427-5619424 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 561.7;Muller glia cells: 151.8" "Cancer enhanced" "Detected in all" "glioma: 20.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 55.4;Karpas-707: 90.9;U-266/70: 45.0" "CAB009189, HPA064431" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Cytosol" "CAB009189: , HPA064431: AB_2685262" "unprognostic (4.40e-2)" "unprognostic (1.02e-1)" "unprognostic (3.16e-2)" "unprognostic (3.65e-2)" "unprognostic (4.00e-2)" "unprognostic (1.23e-3)" "unprognostic (4.13e-2)" "unprognostic (1.50e-2)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "prognostic favorable (7.57e-4)" "unprognostic (2.99e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (6.69e-2)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (1.34e-2)" 27.9 4.0 3.6 27.8 3.7 25.0 22.1 3.2 5.3 22.9 3.5 10.8 5.8 13.8 1.8 16.2 14.4 13.4 15.7 2.9 3.7 9.4 5.3 26.9 38.1 5.5 3.8 5.8 3.2 1.8 4.1 12.1 5.5 13.2 7.8 0.3 10.8 9.0 7.7 50.8 31.1 9.7 3.7 56.3 6.9 6.1 4.0 15.1 21.8 7.7 32.4 15.8 27.7 4.1 14.2 0.0 0.0 0.0 8.6 10.2 1.8 6.9 6.3 2.6 5.7 0.2 5.5 5.3 20.8 7.6 1.1 6.5 0.0 23.4 4.0 55.4 0.0 1.4 4.8 0.5 7.1 0.0 1.6 6.6 14.5 20.7 13.7 10.4 25.6 1.1 13.0 90.9 11.8 0.0 0.1 4.6 0.0 0.0 0.3 6.0 4.0 23.0 0.0 4.8 0.7 0.0 0.0 0.2 0.4 0.6 0.0 0.5 25.2 5.3 3.0 3.2 1.1 45.0 15.9 4.1 8.7 0.6 0.3 18.3 7.1 5.0 5.9 4.9 6.6 4.4 5.1 6.3 5.0 4.9 5.5 5.2 18.9 4.2 8.6 0.5 7.7 4.6 3.6 3.7 3.2 5.3 2.9 3.7 5.5 3.8 5.5 3.7 4.0 4.1 46.4 0.0 7.8 1.3 29.0 17.7 7.1 8.0 15.4 60.6 2.7 6.2 4.9 2.8 10.4 7.3 4.2 0.8 30.3 0.3 3.9 0.4 561.7 4.9 18.0 26.9 77.9 3.6 2.9 0.0 1.1 31.6 3.6 1.0 3.8 7.8 44.6 0.6 7.0 85.8 1.5 1.2 0.0 23.0 24.3 93.4 25.4 26.2 7.2 56.2 27.0 151.8 26.8 1.5 0.8 7.0 0.0 28.2 25.9 2.0 0.0 0.4 12.7 11.6 6.6 33.1 17.3 25.0 11.0 10.7 24.9 1.5 37.6 3.6 0.2 8.0 NLRP13 "CLR19.7, NALP13, NOD14, PAN13" ENSG00000173572 "NLR family pyrin domain containing 13" Q86W25 19 55891699-55932336 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060459 Uncertain NA NA "Cluster 64: Astrocytes - Nervous system maintenance" "HPA060459: AB_2684284" "unprognostic (2.16e-1)" "unprognostic (4.66e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NLRP5 "CLR19.8, MATER, NALP5, PAN11, PYPAF8" ENSG00000171487 "NLR family pyrin domain containing 5" P59047 19 55999726-56061810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "parathyroid gland: 22.4" "Cell type enhanced" "Detected in some" "Microglial cells: 1.0;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Karpas-707: 1.3;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047260, HPA056271" Uncertain Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "HPA047260: , HPA056271: AB_2683083" "unprognostic (9.67e-2)" "unprognostic (2.22e-2)" "unprognostic (5.03e-1)" "unprognostic (7.78e-2)" "unprognostic (1.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 22.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NLRP8 "CLR19.2, NALP8, NOD16, PAN4" ENSG00000179709 "NLR family pyrin domain containing 8" Q86W28 19 55947832-55988629 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 15.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056989 Uncertain NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA056989: AB_2683301" "unprognostic (2.43e-2)" "unprognostic (3.35e-1)" "unprognostic (3.13e-1)" "unprognostic (6.96e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 68.3;brain: 58.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 319.5;Club cells: 164.2;Ductal cells: 123.9" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 90.1" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.0" "Group enriched" "Detected in all" 5 "olfactory bulb: 43.3;pons: 14.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" 68.3 24.0 19.9 4.1 17.9 6.0 30.7 18.2 23.5 8.3 16.3 5.3 3.1 7.5 4.9 6.9 8.6 4.8 5.4 21.4 58.9 10.7 3.1 6.2 5.7 29.3 22.7 7.1 8.4 4.5 9.8 1.9 26.2 5.0 2.9 3.0 7.4 2.5 2.5 4.9 4.1 4.7 22.4 4.8 5.5 11.9 21.4 4.5 17.7 3.1 3.0 8.5 6.5 44.7 90.1 35.3 6.1 1.3 17.1 7.7 0.8 4.7 10.5 12.5 16.6 12.9 23.5 3.4 12.9 14.7 0.1 15.0 34.0 7.0 7.4 30.3 36.7 12.4 13.2 59.7 4.4 8.2 13.6 7.6 2.8 18.2 7.2 7.6 17.9 23.3 0.2 1.4 6.9 55.2 8.8 30.0 22.9 18.0 8.9 25.7 0.1 38.7 11.5 7.3 3.1 34.6 8.2 5.1 40.5 6.0 5.9 33.8 4.0 2.4 10.3 10.3 7.9 0.7 9.9 8.2 26.3 52.9 14.1 0.0 1.0 7.8 7.9 0.7 2.9 5.9 5.9 7.7 4.5 11.3 5.8 4.1 1.6 1.8 0.5 13.4 7.6 3.4 19.9 17.9 18.2 23.5 21.4 58.9 29.3 22.7 26.2 22.4 21.4 44.7 39.0 3.2 2.7 5.5 13.6 15.6 29.5 319.5 21.6 1.9 30.7 37.6 3.5 20.0 164.2 31.3 0.0 2.4 25.3 5.3 13.7 123.9 33.7 21.3 7.3 19.6 18.6 7.4 0.6 58.2 14.1 19.7 11.2 15.6 5.7 12.0 7.5 3.7 32.3 5.0 1.2 6.5 18.3 8.8 86.4 29.0 4.4 26.0 33.8 1.9 18.5 6.5 25.7 2.0 1.0 45.2 5.1 3.8 32.5 39.3 0.8 32.0 57.8 4.1 13.1 22.5 28.6 24.0 21.6 29.5 12.8 3.1 19.7 8.2 9.1 60.6 NMNAT2 "C1orf15, KIAA0479, PNAT2" ENSG00000157064 "Nicotinamide nucleotide adenylyltransferase 2" Q9BZQ4 1 183248237-183418380 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.5;heart muscle: 18.3;pituitary gland: 18.4" "Cell type enhanced" "Detected in many" "Early spermatids: 54.3;Excitatory neurons: 195.5;Inhibitory neurons: 265.4;Oligodendrocyte precursor cells: 98.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 26.2;SCLC-21H: 80.6;SuSa: 25.1;U-2197: 45.8;U-87 MG: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015708, HPA061714" Enhanced Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015708: , HPA061714: AB_2732669" "unprognostic (3.70e-1)" "unprognostic (7.98e-3)" "unprognostic (8.83e-2)" "unprognostic (4.16e-2)" "unprognostic (8.95e-2)" "unprognostic (9.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.35e-1)" "unprognostic (7.92e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.73e-3)" "unprognostic (2.90e-3)" "unprognostic (1.87e-1)" "unprognostic (7.51e-2)" "unprognostic (1.02e-1)" 8.5 5.9 13.1 0.8 14.8 0.0 5.1 17.2 45.5 2.1 0.0 2.3 0.4 1.2 1.4 0.8 2.3 2.8 18.3 15.6 21.4 0.4 0.0 0.7 0.6 0.7 0.8 0.4 1.7 0.2 18.4 0.9 6.7 0.2 0.9 6.5 0.5 2.5 0.5 0.9 0.9 1.5 0.0 0.1 1.1 8.9 0.8 0.5 6.0 1.4 0.6 0.7 0.8 10.0 1.4 0.5 5.5 0.0 3.1 12.5 4.6 3.4 8.9 1.8 0.6 2.7 5.4 0.0 14.2 0.8 1.5 2.2 0.2 0.1 3.3 0.0 0.1 0.0 2.2 0.0 0.5 0.0 0.1 26.2 1.1 2.1 0.5 11.1 0.5 0.0 0.0 0.1 2.1 0.1 0.0 0.5 9.7 0.1 5.4 0.0 0.2 0.0 5.9 4.5 80.6 6.2 0.7 0.3 0.0 25.1 0.7 1.5 3.0 2.5 0.9 45.8 3.3 0.6 0.0 0.0 35.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.8 17.2 45.5 15.6 21.4 0.7 0.8 6.7 0.0 0.8 10.0 21.4 0.0 1.5 3.9 0.0 0.8 0.2 0.6 0.6 12.1 0.2 0.1 35.2 0.0 2.0 0.0 0.0 0.7 0.1 0.1 0.0 0.2 54.3 2.7 0.3 5.2 0.0 0.0 195.5 0.0 12.9 5.7 0.0 7.4 0.0 0.2 0.0 0.0 0.7 20.2 265.4 0.0 4.1 1.0 0.0 42.3 0.0 0.5 1.8 11.2 0.0 0.3 0.0 98.5 6.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 3.4 2.9 19.7 0.3 12.0 0.4 0.2 0.1 0.3 1.4 0.2 0.0 0.0 0.0 NNAT Peg5 ENSG00000053438 Neuronatin Q16517 20 37521206-37523690 "Predicted membrane proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 11 "pituitary gland: 1586.9" "Cell type enhanced" "Detected in many" "Early spermatids: 42.0;Excitatory neurons: 33.9;Late spermatids: 65.5;Muller glia cells: 177.1" "Group enriched" "Detected in many" 16 "glioma: 87.5;testis cancer: 55.0;urothelial cancer: 37.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 22 "SH-SY5Y: 720.8" "Low region specificity" "Detected in all" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (1.18e-2)" "unprognostic (7.41e-3)" "unprognostic (1.85e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (9.66e-4)" "unprognostic (7.08e-2)" "unprognostic (1.42e-1)" "unprognostic (2.36e-1)" "unprognostic (4.05e-2)" "unprognostic (7.52e-2)" "unprognostic (4.94e-2)" "unprognostic (1.64e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (1.96e-1)" "unprognostic (1.15e-3)" "unprognostic (5.90e-2)" 27.4 15.1 109.4 2.5 141.4 2.5 32.5 15.8 65.2 7.4 56.2 76.2 4.0 4.9 0.2 3.4 3.6 4.7 2.7 105.8 70.9 1.6 2.0 2.1 1.4 45.7 49.7 1.5 1.4 0.0 1586.9 106.5 49.3 4.4 4.0 31.4 6.6 0.6 13.5 5.1 14.6 5.1 22.3 1.4 16.8 5.0 93.5 11.1 2.0 0.3 0.1 14.5 5.6 29.6 2.2 1.7 12.6 1.7 0.0 0.0 4.5 0.5 0.0 0.1 0.0 4.2 2.2 1.0 0.7 0.0 0.2 10.2 0.0 0.0 0.0 0.1 0.3 0.3 12.9 2.4 3.2 1.3 1.1 2.9 0.0 0.0 0.0 0.2 32.5 0.3 0.2 2.4 0.1 1.0 5.7 1.3 0.9 0.3 1.6 0.5 4.0 0.5 0.0 20.6 1.9 720.8 1.1 5.0 0.0 0.6 1.3 0.2 0.8 5.7 0.8 1.6 1.1 0.9 0.2 0.1 1.7 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 109.4 141.4 15.8 65.2 105.8 70.9 45.7 49.7 49.3 22.3 93.5 29.6 0.3 0.0 0.0 1.6 0.2 4.0 0.8 0.1 19.9 4.5 0.3 5.8 0.1 0.0 0.7 0.0 0.0 0.6 0.3 0.1 0.0 0.2 42.0 0.1 3.0 21.6 0.0 0.0 33.9 0.0 1.1 3.1 0.0 0.1 1.3 2.2 0.0 0.0 1.6 0.0 9.6 0.2 0.0 0.3 1.1 65.5 0.6 0.1 1.8 4.7 0.0 177.1 0.0 2.0 1.8 0.0 0.0 1.2 0.0 2.5 0.0 0.0 1.1 6.5 0.0 1.4 1.9 1.5 5.6 3.6 1.0 0.3 0.1 0.1 0.0 4.8 NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.1;tongue: 384.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 344.3;Hepatocytes: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975" Enhanced Approved Mitochondria,Cytosol NA NA 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "CAB004975: AB_425908, HPA004829: AB_1079495" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favorable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" 26.0 16.5 12.8 11.8 16.0 15.0 13.7 11.2 21.7 16.4 34.9 25.9 17.2 11.0 16.7 16.8 10.7 15.0 137.7 16.1 11.5 57.0 116.4 13.2 16.5 10.3 12.0 10.1 17.8 55.6 9.6 12.7 9.5 18.3 27.8 12.9 26.6 18.2 239.1 10.4 16.1 20.6 9.3 11.5 31.2 6.2 15.8 26.8 31.1 384.0 17.2 17.3 9.3 15.1 15.4 12.6 30.5 59.6 44.0 50.3 9.9 17.5 39.8 24.8 20.8 19.0 30.4 18.5 21.5 43.9 22.3 16.6 120.5 5.4 27.4 31.1 33.6 24.0 70.7 23.8 27.5 50.2 43.1 37.9 17.5 16.3 18.6 42.6 56.3 22.7 21.4 81.3 60.0 15.1 55.8 35.8 6.4 0.1 15.2 54.7 73.8 70.8 58.0 15.5 44.2 37.7 62.9 1.4 46.7 6.9 47.7 58.3 23.2 29.5 28.3 12.0 8.3 36.1 45.1 26.5 7.1 68.8 22.1 12.5 18.2 16.0 16.7 23.0 17.1 12.0 17.1 15.5 32.0 12.0 15.5 14.7 2.9 23.2 24.7 9.1 22.2 19.3 12.8 16.0 11.2 21.7 16.1 11.5 10.3 12.0 9.5 9.3 15.8 15.1 12.0 54.5 37.8 60.7 19.6 11.5 9.5 19.0 13.1 17.9 9.6 6.3 344.3 38.6 27.0 27.6 35.5 8.7 20.4 34.4 27.4 14.4 16.7 18.5 16.6 19.2 19.9 34.9 124.8 10.7 2.3 27.2 23.9 25.1 25.2 26.8 21.0 314.3 25.0 6.7 110.6 22.6 20.3 40.6 11.9 4.6 14.9 19.8 14.2 45.9 25.9 12.5 35.0 77.9 63.4 9.5 16.7 19.2 20.0 11.7 23.6 21.7 18.1 12.8 0.0 14.0 20.1 4.0 1.4 17.6 8.1 2.1 20.9 18.8 28.9 9.9 NOCT "Ccr4c, CCR4L, CCRN4L, NOC" ENSG00000151014 Nocturnin Q9UK39 4 139015781-139045939 "Predicted intracellular proteins" "Biological rhythms" "Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Glandular and luminal cells: 20.6;Syncytiotrophoblasts: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012287, HPA053714" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA012287: AB_2668640, HPA053714: AB_2682238" "unprognostic (2.16e-1)" "unprognostic (2.16e-3)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (3.36e-3)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.86e-1)" "unprognostic (5.64e-3)" "unprognostic (4.63e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-4)" "prognostic unfavorable (6.23e-4)" 8.2 2.0 2.8 3.2 2.6 36.3 4.5 1.7 7.1 1.4 0.0 1.8 1.2 1.6 0.5 1.9 1.0 5.5 2.9 5.0 2.9 3.6 13.9 2.9 2.1 1.5 3.4 0.6 3.0 1.7 2.2 5.6 2.6 1.0 1.6 3.4 1.6 0.5 6.5 2.2 2.2 3.0 1.4 1.7 1.7 2.2 4.4 1.9 1.5 6.1 2.6 4.9 1.3 2.9 6.5 7.1 2.9 5.7 6.6 2.7 17.2 9.4 6.9 13.7 10.0 10.3 2.8 22.7 7.4 7.3 18.4 4.5 15.8 8.9 13.7 9.5 6.1 10.3 4.4 8.7 6.2 15.3 6.0 3.2 4.4 15.4 10.4 2.7 6.3 4.3 18.6 7.0 6.6 8.0 10.0 7.8 10.1 3.0 8.1 8.5 8.6 7.7 9.4 4.3 11.3 7.3 6.0 6.8 5.6 11.2 5.0 11.2 8.7 7.7 9.4 7.2 11.8 5.9 5.5 14.0 7.0 29.8 9.9 0.8 0.5 0.3 1.0 0.6 0.5 0.4 0.4 0.5 0.2 0.7 0.3 0.6 2.7 0.6 1.6 0.6 0.3 0.1 2.8 2.6 1.7 7.1 5.0 2.9 1.5 3.4 2.6 1.4 4.4 2.9 10.9 9.6 1.1 0.0 2.8 0.0 2.7 0.0 5.7 5.6 2.7 2.5 0.0 1.5 0.6 0.0 14.6 6.1 4.7 0.6 1.9 2.3 0.7 10.4 6.3 2.6 0.0 1.7 0.0 0.2 11.8 2.9 6.1 20.6 2.5 0.8 1.1 2.6 1.5 1.7 0.0 0.4 0.0 1.6 0.0 0.1 0.9 6.9 0.0 0.0 0.1 0.6 4.1 0.0 0.0 2.5 0.0 0.0 5.5 2.5 2.6 4.0 0.7 5.2 0.0 5.4 4.3 1.0 3.9 6.5 0.0 12.0 4.3 0.8 0.2 2.3 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 167.0;Endothelial cells: 129.6;Hepatic stellate cells: 172.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 10.1;HEL: 41.9;K-562: 31.8;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA044384: AB_2678922, HPA076885: " "unprognostic (4.74e-2)" "unprognostic (2.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.27e-1)" "unprognostic (3.15e-3)" "unprognostic (3.02e-6)" "unprognostic (4.89e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-4)" "unprognostic (5.47e-3)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (6.47e-2)" "unprognostic (4.98e-2)" 32.6 20.4 6.1 4.6 5.8 0.3 31.4 5.0 7.6 17.5 4.2 15.3 14.0 14.9 4.3 5.1 16.4 14.0 16.1 4.9 5.6 32.6 7.3 30.8 4.6 6.6 6.0 10.6 22.6 3.8 3.8 25.4 6.5 13.3 16.4 0.8 48.9 6.8 5.1 7.3 14.3 12.8 5.5 5.5 23.0 14.4 6.6 1.9 13.5 3.6 3.0 8.1 11.3 5.0 0.0 3.6 1.1 0.0 0.0 0.0 10.1 0.4 0.0 0.0 0.0 6.3 6.5 0.1 4.3 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 41.9 1.8 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 31.8 0.0 0.0 0.1 0.1 0.1 0.1 20.5 0.3 0.4 1.9 0.0 3.4 1.6 0.0 0.1 0.2 1.9 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.2 0.6 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 5.0 7.6 4.9 5.6 6.6 6.0 6.5 5.5 6.6 5.0 167.0 9.6 10.3 2.0 1.6 1.0 0.6 0.3 0.6 0.1 20.0 11.0 7.1 15.7 3.3 3.7 0.0 18.9 0.4 57.3 13.7 8.0 26.6 16.3 3.3 129.6 11.4 2.7 0.4 21.8 7.0 6.1 41.3 23.2 0.0 72.4 172.5 1.0 1.6 0.0 0.5 35.9 0.0 6.3 0.9 60.9 8.7 1.2 24.9 55.3 0.7 1.6 0.0 2.0 0.0 17.7 53.4 5.7 0.2 3.3 43.1 59.0 1.5 0.3 72.3 1.3 11.3 13.7 1.8 0.4 0.4 26.3 0.9 71.9 20.7 1.2 NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 263.8;Endothelial cells: 121.0;Hepatic stellate cells: 188.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" 24.2 4.0 0.0 0.5 0.0 0.0 19.8 0.0 0.0 5.8 0.0 3.6 0.5 7.2 3.2 2.7 5.8 0.0 15.8 0.0 0.0 8.5 2.5 18.5 0.4 0.0 0.1 2.8 2.6 0.0 3.0 1.4 0.0 6.0 0.1 0.0 2.6 0.0 5.6 2.8 3.9 0.0 0.0 2.6 3.9 0.9 0.0 0.0 9.6 0.0 0.1 5.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 263.8 0.0 6.1 0.0 6.0 5.2 32.1 9.9 13.6 2.7 2.6 6.6 8.7 0.0 4.2 5.5 4.2 0.4 11.9 0.6 0.0 2.6 46.0 2.6 3.1 121.0 6.0 12.0 0.2 1.1 0.3 4.7 0.0 1.0 0.0 1.8 188.8 2.3 1.7 6.7 0.2 0.8 4.1 9.3 5.2 35.6 7.2 6.8 3.6 10.3 1.6 21.0 0.0 0.0 0.5 0.4 0.3 5.3 0.7 18.0 1.0 0.9 3.1 3.6 0.0 7.8 9.3 5.5 1.9 1.9 1.6 0.3 3.6 3.7 0.9 5.6 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 135.7" "Cell type enriched" "Detected in some" 45 "Extravillous trophoblasts: 1002.5" "Cancer enhanced" "Detected in many" "stomach cancer: 48.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 428.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" NA NA 1900000 "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" 0.0 0.1 1.6 0.0 1.9 0.0 0.2 0.6 1.8 0.2 0.1 0.0 1.1 2.1 0.3 0.3 0.4 0.2 0.3 1.0 1.0 1.2 10.0 2.2 0.0 1.7 2.7 0.1 0.4 0.9 0.2 135.7 1.3 0.3 0.0 0.0 0.6 0.1 8.2 2.2 0.3 0.1 0.9 0.2 2.1 2.8 1.3 0.0 0.0 0.5 0.0 1.4 0.2 0.8 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 10.0 0.4 0.0 1.8 0.3 0.2 0.4 2.4 0.0 0.0 0.1 1.1 2.2 2.8 428.6 0.2 0.4 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.2 11.2 0.0 0.0 0.6 0.0 0.2 0.1 67.9 0.4 0.0 0.2 0.1 0.0 0.2 15.7 1.6 4.2 1.7 6.2 2.3 0.1 4.9 0.0 0.5 6.3 0.0 0.2 0.1 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 0.6 1.8 1.0 1.0 1.7 2.7 1.3 0.9 1.3 0.8 0.0 0.0 3.7 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.6 1.3 1.2 0.0 0.0 0.0 0.0 10.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.8 0.0 0.0 0.6 0.0 1002.5 1.2 1.5 0.3 0.0 0.1 0.0 3.6 18.4 0.0 1.1 0.1 0.0 0.0 0.3 0.2 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.5 12.7 0.0 0.0 22.0 0.1 0.0 0.3 0.0 NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 138.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 14.3;HUVEC TERT2: 27.7;TIME: 70.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-3)" "unprognostic (6.58e-3)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (8.83e-3)" "unprognostic (8.95e-3)" "unprognostic (3.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.14e-4)" "unprognostic (1.99e-4)" "unprognostic (9.71e-2)" "unprognostic (5.69e-2)" "unprognostic (3.03e-3)" 7.8 0.7 0.7 0.7 1.2 0.2 3.8 0.7 1.2 1.5 0.0 1.2 0.2 4.9 0.4 0.4 1.3 2.4 7.6 0.4 0.6 138.0 0.3 1.5 0.2 1.0 0.7 0.8 0.3 3.6 0.9 3.1 0.9 1.0 0.3 17.1 3.0 1.3 1.7 1.4 0.6 3.4 0.8 0.4 0.5 0.3 0.7 0.1 2.1 3.5 0.5 1.4 1.1 1.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.5 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.1 14.3 27.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 6.1 0.0 0.0 0.3 7.1 0.4 0.0 70.6 0.2 5.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 1.2 0.7 1.2 0.4 0.6 1.0 0.7 0.9 0.8 0.7 1.7 4.4 0.0 0.0 2.9 1.0 0.6 0.1 0.4 0.0 7.5 0.2 0.3 1.0 0.0 0.0 11.0 6.2 2.2 0.2 0.1 15.6 0.0 0.8 1.0 1.4 5.9 0.0 0.0 30.0 0.0 0.8 9.2 0.0 3.0 0.0 0.6 2.5 0.1 0.2 0.0 21.1 0.0 0.0 0.0 0.5 0.7 0.3 1.3 0.0 6.5 0.1 4.5 0.0 7.1 28.4 0.1 0.0 1.2 0.3 0.1 0.0 164.0 0.0 27.1 0.0 1.2 1.0 0.6 0.7 0.1 0.3 2.5 1.1 0.1 0.0 0.1 NPAS1 "bHLHe11, MOP5, PASD5" ENSG00000130751 "Neuronal PAS domain protein 1" Q99742 19 47019837-47045775 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;skin 1: 7.7" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 16.7;Gastric mucus-secreting cells: 27.0;Inhibitory neurons: 28.3" "Cancer enhanced" "Detected in many" "testis cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 9.9;Daudi: 10.2;HEK 293: 11.1;HMC-1: 9.0;NB-4: 18.1;U-266/84: 11.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA043364, HPA072259" Approved Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA043364: , HPA072259: AB_2686500" "unprognostic (2.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.32e-4)" "unprognostic (1.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-3)" "unprognostic (2.21e-2)" "unprognostic (1.09e-1)" "unprognostic (3.75e-1)" "unprognostic (5.91e-2)" "unprognostic (2.64e-1)" "unprognostic (2.14e-8)" "unprognostic (8.82e-2)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (4.20e-2)" 0.9 0.4 3.1 0.3 1.8 0.2 0.7 0.3 6.3 0.4 1.9 0.4 0.0 0.1 0.0 1.0 0.6 0.0 1.1 5.4 2.8 1.7 0.6 0.4 0.5 2.9 2.5 0.2 0.6 0.0 1.3 0.1 4.3 0.4 0.0 0.5 0.4 0.0 0.1 7.7 0.4 0.1 0.7 2.8 2.7 0.6 1.5 0.1 0.5 0.0 0.3 0.4 0.7 2.0 0.2 2.4 0.3 0.5 0.2 0.2 0.0 9.9 0.3 0.1 0.4 0.7 0.5 10.2 2.2 8.1 0.4 0.2 2.1 0.2 0.1 0.7 11.1 0.8 1.2 2.5 0.0 5.5 9.0 0.9 0.4 0.0 0.1 0.6 0.2 1.3 3.5 0.8 1.3 0.9 0.4 18.1 2.4 0.4 1.7 0.9 0.4 0.8 0.6 0.6 0.7 0.6 0.8 0.3 2.4 0.8 2.1 1.7 0.1 0.2 0.9 0.1 0.2 5.4 11.5 2.2 1.2 1.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 0.3 6.3 5.4 2.8 2.9 2.5 4.3 0.7 1.5 2.0 0.1 0.0 0.6 1.6 1.1 0.8 1.4 1.1 1.8 0.7 2.2 2.5 1.1 0.0 1.1 0.0 16.7 0.0 0.1 0.3 0.0 0.6 0.1 0.4 0.2 0.2 1.2 2.7 5.7 0.4 0.1 0.5 27.0 0.4 0.0 0.7 0.0 0.1 0.3 0.0 28.3 1.4 2.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 5.4 0.0 2.0 1.2 1.0 0.2 0.0 2.6 1.5 0.0 0.9 2.0 5.4 0.0 0.1 1.1 0.4 2.1 2.2 2.3 0.0 1.2 0.1 0.6 1.2 NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "epididymis: 16783.1" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2034.2;Hofbauer cells: 2898.5;Kupffer cells: 2035.4" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 769.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 668.7;classical monocyte: 1300.7;intermediate monocyte: 1772.7;myeloid DC: 587.8;neutrophil: 674.2;non-classical monocyte: 1252.1;plasmacytoid DC: 2113.2" "Group enriched" "Detected in all" 5 "dendritic cells: 2113.2;granulocytes: 674.2;monocytes: 1772.7" "Cell line enhanced" "Detected in all" "ASC diff: 1619.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" NA NA 53000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032888: AB_2157036, HPA000835: AB_1079499" "unprognostic (1.27e-3)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (6.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.97e-1)" "prognostic favorable (6.55e-4)" "unprognostic (1.42e-1)" 260.1 297.0 127.1 261.3 145.4 305.3 221.3 152.2 190.6 284.5 434.0 259.7 201.7 196.7 16783.1 185.0 170.0 356.0 215.1 118.1 156.9 322.4 202.4 786.0 360.3 185.7 145.6 283.1 219.9 241.3 197.5 263.1 179.2 164.2 220.8 48.6 221.9 261.3 58.7 181.6 193.3 180.5 151.1 305.6 206.8 156.8 172.1 134.4 444.7 114.7 241.9 347.4 187.9 195.5 297.2 199.3 124.8 179.4 1619.3 498.6 404.8 194.1 707.1 200.9 398.9 351.7 420.3 78.6 141.6 181.9 372.6 595.9 170.0 405.5 188.6 120.4 126.3 29.6 96.7 296.2 348.6 51.0 548.4 467.7 388.9 173.7 336.9 930.2 298.1 87.0 32.9 601.4 224.0 106.9 70.1 75.9 52.9 489.0 307.9 39.5 219.1 281.6 511.1 735.0 5.5 91.3 296.3 120.3 298.0 359.6 205.2 225.7 268.9 291.9 342.0 396.1 188.2 253.7 452.5 24.2 292.1 168.4 163.4 668.7 1300.7 274.1 92.2 1772.7 87.9 295.2 126.5 92.3 587.8 241.8 120.9 100.5 674.2 99.5 1252.1 2113.2 187.8 1304.5 127.1 145.4 152.2 190.6 118.1 156.9 185.7 145.6 179.2 151.1 172.1 195.5 154.9 381.4 2034.2 11.1 160.2 374.9 557.8 1074.2 170.2 9.9 138.6 220.5 55.4 163.0 626.9 331.1 22.9 228.3 664.0 301.0 305.2 500.4 90.9 123.8 168.5 276.5 119.7 65.4 2.1 279.4 803.3 318.1 61.7 161.0 341.4 104.2 447.3 195.6 2898.5 8.4 3.8 264.8 832.1 2035.4 750.9 69.6 566.7 1462.6 602.9 6.5 790.5 167.4 117.4 7.5 24.4 368.3 405.1 291.9 287.4 357.9 298.1 969.0 393.3 25.1 131.5 118.3 155.9 268.1 166.7 182.6 320.7 210.4 109.9 330.0 298.5 521.6 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.1" "Group enriched" "Detected in many" 6 "Adipocytes: 99.6;Endothelial cells: 52.5;Hepatic stellate cells: 132.8" "Group enriched" "Detected in all" 4 "ovarian cancer: 39.2;renal cancer: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 158.5" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 67.1 8.7 1.7 3.4 1.5 0.0 44.3 1.4 1.4 8.8 1.5 10.1 1.5 31.0 5.5 4.3 36.4 5.9 15.8 1.3 1.4 28.8 4.3 24.2 2.3 1.5 1.5 27.7 3.9 8.4 3.8 17.7 1.5 4.4 2.0 0.1 3.7 12.1 7.2 6.6 9.3 9.7 1.8 2.2 8.8 1.3 2.4 1.9 14.0 11.1 1.3 12.8 9.7 1.4 0.0 1.3 0.1 0.0 158.5 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 28.0 0.0 19.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 15.9 0.0 0.0 2.1 0.0 0.1 0.0 1.9 0.0 5.7 1.0 0.1 0.0 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.5 1.4 1.4 1.3 1.4 1.5 1.5 1.5 1.8 2.4 1.4 99.6 0.0 6.9 0.0 0.2 1.5 0.5 0.0 0.6 0.0 0.5 0.5 4.5 2.8 0.0 14.7 0.0 0.2 0.1 0.0 0.0 0.7 9.1 6.2 8.8 52.5 0.0 0.0 0.0 0.0 1.3 15.2 0.0 15.4 0.0 0.0 132.8 2.4 0.3 0.0 0.0 0.0 0.0 4.7 4.0 11.5 10.2 0.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.0 0.0 4.1 0.0 0.5 0.0 4.0 0.0 0.0 0.0 1.4 2.2 0.5 0.1 0.2 1.0 0.7 0.3 1.4 0.2 0.0 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Excitatory neurons: 69.1;Inhibitory neurons: 68.9;Microglial cells: 34.7;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 30.9;ASC TERT1: 21.1;BJ hTERT+: 20.2;HHSteC: 20.1;HSkMC: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 12.4 8.2 9.3 1.7 9.4 0.3 10.3 14.4 9.9 25.7 7.7 15.6 1.8 20.5 8.7 3.2 15.1 3.2 12.8 9.1 11.4 6.7 8.6 9.1 2.3 11.8 9.4 9.4 3.2 1.3 13.8 4.7 11.5 10.9 2.8 4.1 5.3 6.5 10.8 8.3 7.5 9.9 8.2 4.9 7.8 4.8 10.7 2.2 6.0 8.6 1.7 12.1 14.7 7.9 0.0 2.9 2.2 0.0 30.9 21.1 1.9 9.3 20.2 7.0 6.4 4.5 4.3 1.8 3.0 17.9 12.8 1.2 3.6 0.2 6.1 2.2 1.0 1.8 4.3 3.4 20.1 0.4 0.0 23.8 1.8 8.9 0.6 7.6 12.7 2.5 0.7 0.2 13.4 1.0 0.5 0.8 3.5 1.0 3.7 2.4 0.2 0.5 1.8 1.4 1.1 0.7 0.4 0.1 0.6 3.8 0.2 0.0 8.2 8.5 7.8 3.2 1.2 0.5 0.6 4.8 10.4 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 9.3 9.4 14.4 9.9 9.1 11.4 11.8 9.4 11.5 8.2 10.7 7.9 2.7 3.2 3.4 35.6 0.0 1.1 0.6 0.6 1.2 5.1 0.7 1.4 0.7 1.5 0.3 0.0 2.1 0.4 0.5 0.7 0.0 0.6 0.3 1.4 9.2 4.4 0.0 0.0 69.1 0.8 0.2 7.2 0.5 2.0 1.3 9.6 6.1 4.5 0.4 3.3 68.9 0.7 0.0 0.3 2.1 0.3 9.3 0.3 0.0 34.7 0.0 6.8 0.0 51.8 16.3 0.6 3.6 7.9 0.2 2.7 0.2 0.6 1.1 2.2 0.0 5.1 3.4 4.5 3.1 0.1 1.6 0.3 0.7 0.8 1.1 0.4 NQO2 "DHQV, DIA6, NMOR2, QR2" ENSG00000124588 "N-ribosyldihydronicotinamide:quinone reductase 2" P16083 6 2987987-3019755 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 202.5;Proximal tubular cells: 730.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 240.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021283, HPA021332" Enhanced Supported Nucleoplasm,Cytosol NA NA 6000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA021283: AB_1854600, HPA021332: AB_1854601" "unprognostic (7.11e-3)" "unprognostic (1.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.01e-2)" "unprognostic (1.00e-2)" "unprognostic (3.58e-1)" "prognostic unfavorable (8.40e-4)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (4.90e-2)" "unprognostic (6.59e-2)" "unprognostic (3.60e-2)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" "unprognostic (3.32e-2)" "unprognostic (3.96e-1)" "unprognostic (2.02e-1)" 60.0 121.5 48.1 27.0 48.8 72.1 45.0 61.1 65.4 32.6 64.3 28.2 35.3 25.8 32.9 32.8 30.0 31.5 76.5 48.5 49.6 190.3 124.2 30.4 19.5 61.8 47.9 29.8 42.6 33.5 21.2 28.6 61.4 28.1 19.6 31.1 61.9 28.9 123.6 50.7 35.6 19.8 42.9 39.3 36.1 18.2 51.5 18.3 26.8 144.9 18.2 31.8 29.0 53.2 45.7 75.7 42.1 95.3 73.0 42.9 45.4 40.5 51.2 37.1 40.9 80.0 16.1 36.9 144.7 71.1 86.4 33.7 45.4 28.5 28.9 95.9 37.1 23.6 83.0 77.3 59.7 24.4 73.9 27.8 34.2 44.9 40.9 53.4 36.8 47.9 142.3 24.1 30.8 95.5 27.0 44.4 54.9 87.6 59.8 49.3 50.1 108.2 56.6 24.0 11.4 15.9 59.5 25.9 128.9 75.0 35.4 16.9 60.7 34.8 14.4 45.9 18.1 45.4 116.7 12.3 43.3 69.5 72.7 25.2 91.8 52.8 33.1 64.2 24.4 12.1 29.6 29.8 61.7 9.1 17.8 19.6 240.2 30.0 60.8 6.5 37.2 43.2 48.1 48.8 61.1 65.4 48.5 49.6 61.8 47.9 61.4 42.9 51.5 53.2 30.3 9.6 16.1 9.8 16.3 35.2 41.5 32.7 12.5 34.8 34.2 32.1 72.8 47.1 21.3 25.8 10.4 42.6 18.2 21.2 162.4 29.1 51.6 15.1 21.4 28.0 4.8 43.8 47.0 63.4 53.9 51.5 33.1 9.0 13.9 11.0 25.7 202.5 76.6 42.1 46.7 23.3 30.5 44.7 105.7 62.8 35.8 75.4 67.6 19.7 148.6 54.0 20.6 10.6 9.1 55.8 18.3 41.0 15.0 38.6 103.7 730.3 28.7 22.5 26.3 35.0 42.9 24.8 11.4 35.4 41.2 31.2 20.8 21.9 25.4 41.8 NR1H3 "LXR-a, LXRa, RLD-1" ENSG00000025434 "Nuclear receptor subfamily 1 group H member 3" Q13133 11 47248300-47269033 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.6;Hofbauer cells: 54.4;Kupffer cells: 100.9;Proximal enterocytes: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 13.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 45.3;HSkMC: 61.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036443, CAB037109" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB037109: AB_1840991, HPA036443: AB_10966142" "unprognostic (2.95e-3)" "unprognostic (5.31e-3)" "unprognostic (5.19e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.19e-1)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "unprognostic (7.73e-2)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (3.56e-1)" "unprognostic (4.42e-2)" "unprognostic (2.84e-1)" "prognostic favorable (3.40e-4)" 60.7 19.9 11.3 19.4 11.8 3.3 51.1 11.2 14.3 25.3 10.2 24.6 48.4 13.6 17.6 7.6 20.3 19.6 18.5 10.3 11.1 23.4 83.8 24.1 46.7 11.0 12.1 15.2 16.7 6.8 7.2 25.4 11.7 19.4 12.0 2.2 14.8 11.5 9.1 11.7 41.0 7.9 10.5 53.2 16.3 21.8 13.8 11.0 20.3 6.3 13.6 22.4 17.5 11.5 3.5 13.8 6.4 6.1 41.0 45.3 31.1 3.5 17.9 5.7 8.8 17.0 43.2 6.1 6.5 2.8 2.1 9.2 7.6 6.1 3.8 5.8 6.1 8.3 18.7 26.1 17.5 2.9 1.0 61.2 3.7 8.7 5.5 9.7 5.0 9.4 10.2 2.5 4.5 14.8 5.8 17.0 7.1 18.7 4.5 8.4 8.3 4.1 5.0 31.9 6.1 2.3 12.2 7.9 10.4 6.1 19.5 8.8 1.3 4.5 6.1 9.1 2.0 11.9 18.3 7.6 8.2 3.9 2.2 7.8 2.7 2.5 1.4 13.3 1.9 1.0 1.5 1.3 4.3 0.7 1.7 1.4 1.6 5.8 4.2 0.7 3.8 1.9 11.3 11.8 11.2 14.3 10.3 11.1 11.0 12.1 11.7 10.5 13.8 11.5 27.2 0.0 11.3 8.1 3.0 3.3 8.6 4.6 2.2 2.4 12.7 12.1 6.6 15.7 4.9 5.5 2.1 11.0 1.5 24.4 11.7 5.8 31.0 2.4 15.3 12.5 1.8 7.0 9.2 8.7 13.3 14.1 17.9 2.8 13.3 7.1 24.7 66.6 54.4 1.7 10.9 14.6 2.0 100.9 3.3 49.0 9.0 24.7 3.6 1.0 5.4 4.4 2.1 3.0 5.6 4.2 10.7 6.0 2.4 4.1 69.5 26.1 2.5 0.8 19.7 7.4 16.3 32.4 16.8 3.0 2.4 6.6 2.1 5.4 19.0 6.3 NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.8;liver: 38.6;pancreas: 61.1" "Cell type enriched" "Detected in many" 5 "Granulosa cells: 276.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "A549: 25.0;CACO-2: 6.2;HAP1: 14.9;HMC-1: 6.4;HUVEC TERT2: 20.4" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Not detected" "Not detected" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" 5.4 0.4 0.5 2.6 0.2 0.9 3.7 0.5 0.3 3.4 0.2 11.9 17.4 3.3 1.4 0.9 2.2 8.0 1.0 0.3 2.8 0.7 38.6 2.7 2.1 0.7 0.6 1.0 61.1 0.4 0.1 0.4 0.8 1.6 13.1 0.2 0.5 0.8 1.1 1.1 17.8 4.3 0.4 0.2 1.3 0.8 0.8 0.5 0.9 0.7 1.4 1.8 1.2 0.7 0.0 25.0 0.0 0.1 0.0 0.2 0.6 0.0 0.4 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.7 0.7 14.9 0.0 0.0 3.3 1.1 0.0 0.3 2.7 0.5 0.1 6.4 0.1 0.0 0.0 0.1 0.0 20.4 0.1 0.0 0.3 0.0 0.6 0.0 0.4 0.9 0.0 0.3 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.7 4.7 0.3 0.1 1.0 0.2 0.1 0.2 3.4 2.3 2.6 0.3 0.2 0.1 3.2 0.4 0.4 0.2 0.2 0.2 0.3 0.3 0.3 0.1 0.4 0.4 0.3 1.5 0.5 0.2 0.5 0.4 0.1 0.5 0.2 0.5 0.3 0.3 2.8 0.7 0.6 0.8 0.4 0.8 0.7 23.7 0.0 1.7 0.3 0.2 1.9 0.1 0.0 0.0 0.2 0.2 0.0 9.9 32.9 0.0 0.0 0.0 0.0 0.3 37.5 0.0 38.2 0.4 0.3 0.3 32.4 4.9 2.7 0.4 54.5 0.0 0.8 0.0 0.2 13.3 276.2 38.6 38.5 0.1 0.0 0.6 13.8 0.0 4.9 1.5 0.3 0.6 0.6 0.0 0.0 3.1 0.0 0.0 1.0 0.3 22.0 21.8 0.0 1.2 0.3 49.9 0.0 0.8 0.3 0.0 0.5 6.1 0.1 0.1 0.0 1.4 0.0 0.3 0.1 32.3 0.2 NRARP MGC61598 ENSG00000198435 "NOTCH regulated ankyrin repeat protein" Q7Z6K4 9 137299631-137302271 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 47.9" "Cell type enhanced" "Detected in many" "Adipocytes: 75.3;Basal keratinocytes: 97.0;Langerhans cells: 97.9;Squamous epithelial cells: 101.8;Suprabasal keratinocytes: 381.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 45.1;MCF7: 23.3;NTERA-2: 31.9;OE19: 30.8;T-47d: 23.1;TIME: 31.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025729 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" Cytosol Nucleoplasm "HPA025729: AB_1854633" "unprognostic (9.92e-2)" "unprognostic (1.75e-2)" "unprognostic (1.56e-1)" "unprognostic (7.17e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-1)" "unprognostic (3.42e-2)" "unprognostic (1.89e-2)" "unprognostic (1.00e-2)" "unprognostic (6.42e-2)" "unprognostic (4.73e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.73e-6)" "unprognostic (2.85e-3)" "unprognostic (1.34e-1)" "unprognostic (4.90e-2)" "unprognostic (3.28e-3)" 8.9 1.7 7.8 7.6 7.9 1.5 6.9 8.8 7.8 6.5 4.2 47.9 22.0 4.4 1.2 22.6 3.6 12.0 12.5 7.3 10.8 6.1 2.7 7.1 1.6 11.5 12.6 2.0 16.8 2.7 7.6 10.3 10.5 9.5 30.5 1.5 3.0 2.1 2.9 26.3 17.8 3.4 9.8 4.2 8.7 10.2 14.8 2.7 4.9 6.5 4.1 10.4 13.5 6.6 4.8 1.0 8.0 8.8 0.0 0.0 2.6 0.1 0.2 0.0 0.1 6.8 3.0 0.0 10.2 0.0 0.4 45.1 13.9 0.4 0.1 0.3 20.6 1.4 2.1 7.6 0.8 2.8 4.3 0.0 2.3 0.0 0.6 0.2 11.8 0.1 11.8 0.3 0.0 23.3 0.2 6.4 31.9 30.8 6.7 8.4 1.5 17.7 1.2 0.6 4.9 8.1 1.4 2.4 0.1 1.7 23.1 5.8 31.9 0.0 0.1 0.1 1.9 0.3 0.2 3.0 0.1 5.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 7.9 8.8 7.8 7.3 10.8 11.5 12.6 10.5 9.8 14.8 6.6 75.3 0.0 0.0 33.3 17.6 97.0 5.9 20.1 15.9 0.6 24.4 39.2 4.4 5.7 14.3 0.0 0.0 0.1 9.7 22.4 0.0 0.5 17.3 35.2 4.4 21.9 10.2 0.0 2.5 1.1 0.0 2.1 19.4 43.0 0.0 0.3 8.9 0.1 0.4 0.0 0.4 20.5 8.2 0.6 97.9 5.2 0.0 18.6 17.8 9.4 0.0 6.8 0.0 2.0 0.6 0.6 28.3 0.4 3.9 6.2 5.0 0.1 3.2 2.8 6.6 4.0 32.1 0.1 0.6 101.8 381.0 0.0 6.7 3.7 23.4 6.0 NRIP3 C11orf14 ENSG00000175352 "Nuclear receptor interacting protein 3" Q9NQ35 11 8980576-9004049 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.9;retina: 24.5;testis: 43.5" "Cell type enhanced" "Detected in many" "Early spermatids: 545.3;Horizontal cells: 242.3;Late spermatids: 478.6;Spermatocytes: 189.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 13.1" "Lineage enriched" "Detected in many" 12 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HMC-1: 51.4;SiHa: 34.3;U-87 MG: 47.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058827, HPA072961" Approved Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA058827: AB_2683829, HPA072961: " "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (8.84e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-1)" "unprognostic (2.68e-1)" "unprognostic (2.03e-4)" "unprognostic (1.25e-1)" "unprognostic (1.88e-1)" "unprognostic (3.63e-2)" "unprognostic (1.04e-2)" "unprognostic (1.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.41e-1)" "unprognostic (5.88e-3)" "unprognostic (1.30e-1)" 1.1 10.2 16.7 1.6 13.4 13.8 3.9 23.2 42.1 3.4 0.0 1.5 0.5 3.2 3.1 0.8 2.2 1.6 1.2 72.9 20.8 1.4 0.2 0.8 0.8 20.5 18.4 0.5 0.4 5.4 1.5 0.8 23.6 0.7 0.6 24.5 0.6 0.9 0.3 0.6 0.6 2.3 25.1 0.5 2.5 43.5 31.6 0.9 0.9 0.2 0.6 1.3 0.7 17.2 0.0 0.9 1.9 0.3 0.7 2.7 0.1 20.3 8.0 16.2 16.9 3.1 1.8 0.1 3.0 5.9 9.6 0.2 5.5 0.5 28.0 1.7 8.5 2.2 1.2 0.2 1.4 26.5 51.4 3.7 0.3 16.7 0.1 17.1 13.3 4.4 4.2 0.2 15.0 0.0 1.3 8.6 6.6 0.1 0.0 0.0 2.8 0.0 0.3 1.2 5.4 1.7 34.3 0.9 5.3 1.4 3.5 2.5 16.6 24.7 11.8 1.4 0.1 0.1 0.0 0.0 47.9 3.1 12.3 13.1 0.1 2.0 0.1 0.3 0.2 0.1 0.5 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.1 0.3 16.7 13.4 23.2 42.1 72.9 20.8 20.5 18.4 23.6 25.1 31.6 17.2 4.0 0.0 1.3 1.0 1.7 2.2 5.7 0.5 0.0 19.6 12.1 8.9 1.6 0.0 0.4 0.0 10.4 0.4 7.4 0.6 5.9 0.4 545.3 3.7 4.1 2.5 5.3 2.7 11.5 1.1 0.5 2.5 7.1 6.6 15.8 2.4 0.0 0.0 12.1 242.3 96.3 0.5 8.2 3.1 17.2 478.6 6.8 12.8 3.6 0.0 0.6 4.4 0.0 4.5 1.6 8.2 0.1 5.7 1.2 3.5 0.1 0.0 0.1 10.6 0.0 6.0 3.6 189.8 44.0 0.9 1.0 1.0 5.5 5.6 0.2 4.2 NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.9;parathyroid gland: 81.0" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Endothelial cells: 115.3;Excitatory neurons: 71.9;Extravillous trophoblasts: 64.7;Hepatic stellate cells: 160.3" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 7 "granulocytes: 2.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 140.0;ASC TERT1: 107.6;fHDF/TERT166: 147.5;JURKAT: 134.8;REH: 196.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" 66.4 5.1 49.1 6.4 44.9 0.5 64.2 46.0 80.8 16.2 17.0 21.3 3.7 9.4 4.0 8.2 13.6 11.2 19.7 98.9 27.7 8.2 4.4 15.6 9.6 30.4 29.9 4.7 2.9 81.0 12.3 42.1 32.5 10.1 4.7 23.4 8.7 7.4 17.3 18.8 10.8 10.5 22.1 15.7 10.3 0.6 60.1 3.6 9.4 16.1 3.5 13.8 17.0 45.9 16.7 0.6 1.4 0.1 140.0 107.6 19.1 2.6 0.0 11.8 16.1 0.2 0.1 0.0 2.5 147.5 25.0 0.5 43.3 0.0 11.4 26.1 21.2 13.7 0.0 0.0 0.0 58.0 43.7 17.3 0.0 10.5 0.0 0.1 57.4 134.8 0.2 0.6 42.5 0.1 89.7 2.6 0.1 0.0 0.0 196.3 47.7 0.4 0.2 0.2 24.9 9.2 0.0 0.8 13.9 0.2 0.4 16.4 12.1 56.4 1.6 21.4 36.5 0.1 2.2 0.9 85.8 0.2 8.9 0.0 0.1 0.0 0.1 0.1 2.6 0.3 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 0.1 49.1 44.9 46.0 80.8 98.9 27.7 30.4 29.9 32.5 22.1 60.1 45.9 262.9 0.0 1.3 7.2 1.6 10.5 0.1 0.0 1.2 6.7 1.4 2.4 2.5 1.5 0.0 0.0 2.1 1.5 1.0 0.0 0.0 0.1 0.1 0.0 0.1 115.3 0.0 0.0 71.9 0.5 64.7 15.9 0.0 0.1 0.0 0.0 160.3 0.9 1.8 3.3 3.0 0.0 0.0 4.1 21.5 0.4 0.9 1.4 16.0 8.4 0.5 4.5 0.0 13.6 8.3 0.2 0.0 0.0 1.4 0.4 0.0 0.0 0.0 20.2 0.0 4.4 18.3 0.4 0.3 0.6 11.2 1.4 1.9 0.1 0.0 0.7 NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 366.0;Endothelial cells: 174.4;Hepatic stellate cells: 184.6;Sertoli cells: 282.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 444.6;hTERT-RPE1: 371.6;TIME: 369.5;U-87 MG: 425.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" 125.2 42.3 9.3 43.3 9.4 3.7 62.2 0.0 26.0 36.9 13.3 26.6 21.3 51.6 35.7 19.7 34.5 54.1 80.8 48.6 9.1 52.7 53.1 63.7 23.7 4.0 3.9 43.0 33.0 24.4 9.0 133.7 2.1 21.3 23.6 11.6 19.3 38.4 55.9 22.1 21.0 55.9 5.7 66.7 18.6 12.9 13.4 18.2 49.7 46.6 12.4 35.3 20.0 10.7 57.4 217.8 11.1 1.1 204.8 224.7 1.3 224.4 216.2 109.6 118.2 28.9 132.4 1.1 26.6 444.6 116.8 15.8 13.8 65.2 89.3 0.7 11.2 0.6 24.5 48.7 74.3 20.8 1.6 277.3 11.2 261.7 116.8 371.6 304.0 1.4 0.7 1.4 221.3 96.8 1.4 3.9 5.5 11.9 204.2 9.6 24.8 1.2 109.7 1.3 5.1 2.7 23.0 17.5 0.9 9.2 1.0 3.3 369.5 156.4 36.9 193.0 153.8 0.7 1.1 0.7 425.2 26.4 143.5 0.4 2.5 0.5 0.6 0.4 1.0 0.7 0.7 0.6 2.3 0.6 0.6 0.6 0.4 1.2 0.3 39.3 0.6 0.9 9.3 9.4 0.0 26.0 48.6 9.1 4.0 3.9 2.1 5.7 13.4 10.7 366.0 0.0 20.2 80.3 4.3 15.7 10.6 5.5 7.4 10.5 4.2 5.5 67.6 28.6 13.0 18.4 4.2 61.5 29.4 0.6 1.9 57.9 1.3 11.3 116.9 174.4 4.2 3.2 105.4 18.9 13.4 58.5 6.6 11.0 7.6 62.3 184.6 12.5 135.4 0.0 14.4 1.8 16.2 62.7 33.3 5.5 42.3 46.0 12.4 78.7 5.8 3.4 0.0 11.6 2.3 15.4 0.0 21.1 1.6 4.1 3.0 59.8 5.4 0.9 282.7 13.1 117.9 0.2 1.3 2.7 10.5 67.2 3.8 61.1 1.5 3.3 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 53.0;Hepatocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Lipid droplets" "HPA000248: AB_1079507, HPA000571: AB_1079506" "unprognostic (1.84e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.03e-1)" "unprognostic (5.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.62e-2)" "unprognostic (2.63e-1)" "prognostic favorable (6.09e-5)" "unprognostic (3.53e-2)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (4.79e-2)" 24.0 38.8 13.2 10.2 12.6 8.9 20.2 14.2 13.3 20.3 13.7 13.9 17.6 13.6 44.5 51.7 14.9 7.9 22.4 13.7 14.3 14.9 50.4 12.9 9.1 16.8 15.4 10.3 10.6 12.9 8.8 10.3 18.5 14.8 13.5 10.4 16.7 21.3 10.1 22.6 24.2 12.5 13.4 9.5 13.8 8.9 15.2 9.9 13.3 10.9 18.1 12.1 24.1 15.1 135.6 48.9 65.5 33.8 54.9 41.5 36.2 26.3 35.2 46.9 59.3 68.5 71.7 67.0 86.0 35.9 174.2 67.6 85.5 122.1 41.3 22.0 49.5 27.9 44.7 70.3 39.8 27.6 21.1 51.1 46.3 92.2 23.0 20.2 44.2 28.7 46.4 29.1 36.1 60.1 27.3 35.8 26.0 67.4 58.1 19.9 47.4 54.6 98.9 55.7 23.4 26.5 23.4 34.6 28.4 44.9 23.1 35.0 38.7 21.6 35.4 52.3 51.0 40.9 29.4 114.9 40.0 42.4 20.8 21.0 19.6 18.7 16.3 18.7 16.4 19.1 16.1 14.1 19.4 15.1 11.6 12.7 2.2 19.7 14.2 17.4 20.4 15.2 13.2 12.6 14.2 13.3 13.7 14.3 16.8 15.4 18.5 13.4 15.2 15.1 7.1 12.8 16.7 5.9 6.3 10.8 12.8 53.0 10.8 4.3 11.7 6.1 25.0 15.7 29.0 12.9 0.0 21.5 6.1 9.6 9.8 20.1 13.3 15.5 6.6 9.2 6.0 13.0 2.2 20.3 22.0 9.0 8.2 15.5 8.2 14.0 7.5 55.0 18.6 1.7 2.2 10.2 26.4 8.7 9.6 8.0 8.4 7.9 5.4 1.0 11.0 10.6 7.2 2.5 5.7 21.4 11.9 9.1 11.3 10.4 25.2 16.5 25.4 6.2 0.0 5.9 12.5 3.7 7.8 19.4 12.1 18.6 5.3 25.1 11.2 16.4 NSG1 "D4S234E, NEEP21, P21" ENSG00000168824 "Neuronal vesicle trafficking associated 1" P42857 4 4348140-4419058 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.7;pituitary gland: 135.1;skin 1: 120.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 222.4;Cytotrophoblasts: 120.2;Granulosa cells: 128.8;Melanocytes: 291.7;Suprabasal keratinocytes: 178.2" "Cancer enriched" "Detected in many" 4 "melanoma: 61.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 45.2;MAIT T-cell: 61.9;memory CD4 T-cell: 42.2;memory CD8 T-cell: 37.1;naive CD8 T-cell: 27.6" "Lineage enriched" "Detected in many" 57 "T-cells: 61.9" "Cell line enhanced" "Detected in many" "HAP1: 84.7;SCLC-21H: 168.6;SH-SY5Y: 82.5;SK-MEL-30: 80.9;TIME: 204.6;U-698: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "unprognostic (3.21e-3)" "unprognostic (2.33e-1)" "unprognostic (5.29e-3)" "unprognostic (7.60e-2)" "unprognostic (8.06e-2)" "unprognostic (1.49e-1)" "unprognostic (1.32e-3)" "unprognostic (3.47e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-3)" "prognostic favorable (9.49e-4)" "unprognostic (2.50e-1)" "unprognostic (6.85e-2)" "unprognostic (4.21e-2)" "unprognostic (7.33e-2)" "unprognostic (2.85e-1)" "unprognostic (7.41e-2)" 5.0 25.3 29.0 4.2 33.1 1.0 6.0 59.6 50.7 17.1 5.3 7.9 6.8 7.8 2.1 30.7 20.1 1.3 5.9 18.4 95.7 4.4 0.5 1.5 3.2 57.1 64.8 46.3 1.8 0.1 135.1 18.3 58.8 22.8 7.1 32.3 6.7 18.2 0.7 120.9 5.8 6.9 24.2 2.2 8.0 16.0 45.4 9.5 0.5 3.0 3.5 13.3 30.1 24.2 0.2 0.1 0.8 0.5 0.0 0.0 14.6 0.3 0.0 0.2 0.0 1.3 0.4 0.0 10.4 0.5 3.3 2.4 84.7 5.5 0.4 0.0 3.0 0.0 0.2 0.0 4.1 0.0 0.0 0.1 12.0 0.0 2.3 0.0 14.6 22.3 0.0 0.1 1.3 0.0 6.8 0.5 10.1 0.1 0.4 0.1 0.0 0.4 0.0 4.8 168.6 82.5 0.6 0.2 80.9 7.0 0.9 0.3 204.6 0.0 13.0 0.2 0.3 0.1 0.4 75.9 0.1 0.2 0.4 0.2 0.1 0.1 45.2 0.1 61.9 0.1 42.2 37.1 0.1 0.1 10.4 27.6 1.0 0.9 0.2 0.1 4.5 15.7 29.0 33.1 59.6 50.7 18.4 95.7 57.1 64.8 58.8 24.2 45.4 24.2 1.6 9.6 0.0 5.9 0.4 86.8 83.4 47.9 31.3 222.4 0.7 24.3 0.0 0.0 13.2 0.0 4.2 120.2 6.0 0.0 0.0 0.0 31.2 10.3 1.4 2.1 2.4 0.0 16.6 0.0 15.2 24.9 0.0 16.4 1.3 128.8 1.8 0.0 8.2 8.4 32.2 0.0 4.1 0.0 13.6 44.2 3.1 1.3 291.7 6.5 0.4 6.4 20.6 1.5 4.0 0.1 0.2 5.7 0.7 19.9 0.0 20.4 1.7 24.3 0.0 0.2 10.8 2.9 14.4 44.8 178.2 76.8 17.0 96.0 0.3 77.0 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 58.0;Oligodendrocyte precursor cells: 61.3;Pancreatic endocrine cells: 124.8;Rod photoreceptor cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 807.8;LHCN-M2: 934.3;TIME: 546.2;U-87 MG: 821.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 20.7 6.0 9.8 11.9 11.9 0.6 14.1 11.2 10.7 112.6 14.9 29.4 40.1 49.4 6.3 8.6 20.7 17.2 8.7 8.5 11.3 17.2 54.8 6.8 9.6 11.7 14.1 39.3 1.8 1.8 11.8 25.3 13.0 13.3 31.9 94.4 6.6 34.2 2.1 6.4 20.9 73.9 14.7 13.0 8.1 10.4 12.7 5.2 23.7 9.8 11.3 15.8 28.5 12.1 48.9 26.0 42.9 0.8 95.1 302.4 0.4 306.1 332.7 147.5 275.2 0.4 469.6 0.0 107.3 270.2 379.0 24.5 0.1 308.0 348.8 0.8 0.1 0.1 7.3 6.0 47.5 0.2 0.7 77.4 3.7 302.0 191.3 807.8 124.9 0.3 0.3 1.4 934.3 8.3 0.0 0.2 0.8 8.2 34.6 1.5 9.5 1.3 323.1 21.8 0.3 5.5 3.8 18.8 104.9 2.2 0.4 8.3 546.2 120.6 0.9 152.9 506.8 22.7 15.3 0.5 821.7 0.4 385.3 0.0 0.0 0.5 3.7 0.0 6.4 23.7 4.2 11.7 0.0 33.0 4.1 30.7 0.5 0.7 0.0 0.1 1.7 6.4 9.8 11.9 11.2 10.7 8.5 11.3 11.7 14.1 13.0 14.7 12.7 12.1 6.4 0.0 5.8 36.9 21.6 5.2 1.7 6.1 2.8 4.4 1.2 0.3 1.7 27.1 4.8 1.8 10.4 0.6 2.2 49.2 3.9 3.8 0.6 19.3 20.8 20.5 0.0 0.0 1.6 4.1 2.5 39.4 11.2 58.0 0.0 0.1 49.6 33.7 1.3 0.0 2.1 27.7 0.0 3.5 8.2 1.3 13.1 2.1 7.2 11.2 0.5 9.1 0.0 61.3 0.7 124.8 46.0 25.6 3.6 1.5 8.3 27.6 4.8 81.6 0.0 3.3 9.6 0.0 0.3 0.6 4.8 15.2 5.0 0.1 18.0 9.6 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027054 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 230.0;thyroid gland: 116.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1144.3;Excitatory neurons: 750.1;Inhibitory neurons: 877.7;Oligodendrocyte precursor cells: 557.9" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;HaCaT: 3.0;RPTEC TERT1: 9.7;SH-SY5Y: 11.2;SuSa: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Plasma membrane" NA NA 20000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 40.5 2.7 201.9 1.7 177.8 0.1 62.2 133.3 190.6 9.8 69.8 5.9 0.4 3.9 3.9 8.2 5.6 33.3 15.2 173.3 230.0 20.4 1.8 10.0 3.1 119.4 218.9 9.7 34.3 2.5 10.1 1.8 151.7 4.7 3.6 41.2 14.4 19.1 2.9 11.6 1.6 3.3 116.6 10.9 1.9 2.4 222.1 4.0 116.9 13.8 4.3 4.9 12.0 117.7 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 9.7 0.7 0.7 11.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 201.9 177.8 133.3 190.6 173.3 230.0 119.4 218.9 151.7 116.6 222.1 117.7 17.4 0.0 0.5 1144.3 0.7 56.6 1.0 1.8 93.9 30.3 144.1 116.8 11.4 0.0 0.2 9.2 6.2 0.0 1.0 8.7 27.4 36.1 1.8 1.2 0.4 8.0 0.0 0.0 750.1 0.7 0.1 76.6 0.0 2.3 0.0 0.1 5.0 0.0 0.2 242.3 877.7 0.7 0.0 0.0 14.2 3.6 104.1 1.4 17.8 65.6 0.6 241.0 0.0 557.9 109.5 0.5 7.0 48.2 0.3 0.9 0.0 7.1 1.7 12.2 124.9 9.9 114.4 0.8 2.3 5.2 24.6 0.0 3.3 0.2 7.2 0.9 NTSR2 NTR2 ENSG00000169006 "Neurotensin receptor 2" O95665 2 11658178-11670195 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 58 "brain: 85.4;choroid plexus: 43.7" "Cell type enriched" "Detected in some" 32 "Astrocytes: 32.7" "Cancer enriched" "Detected in single" 15 "glioma: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (5.40e-2)" "unprognostic (2.30e-2)" "unprognostic (2.36e-2)" "unprognostic (5.32e-2)" "unprognostic (2.23e-1)" "unprognostic (1.80e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-1)" "unprognostic (1.64e-1)" 0.5 0.9 74.8 0.0 84.2 0.0 0.2 67.7 78.2 0.0 43.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.7 75.8 0.0 0.0 0.0 0.0 65.8 85.4 1.1 0.2 0.0 0.2 0.0 68.9 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 60.5 0.0 0.0 0.2 82.9 0.0 0.0 0.0 0.0 0.0 0.0 60.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 84.2 67.7 78.2 65.7 75.8 65.8 85.4 68.9 60.5 82.9 60.8 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NUGGC "C8orf80, HMFN0672, SLIP-GC" ENSG00000189233 "Nuclear GTPase, germinal center associated" Q68CJ6 8 28021964-28083936 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "liver: 20.6;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in some" "Hepatocytes: 15.7;Plasma cells: 35.1;Proximal tubular cells: 7.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 3.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 4.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Daudi: 116.5;Karpas-707: 38.6;U-698: 84.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.23e-2)" "unprognostic (2.17e-4)" "unprognostic (1.28e-2)" "unprognostic (1.96e-2)" "unprognostic (2.15e-2)" "unprognostic (1.83e-4)" "unprognostic (2.08e-3)" "unprognostic (6.19e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-3)" "unprognostic (2.45e-1)" "unprognostic (1.95e-1)" "unprognostic (3.39e-3)" "unprognostic (1.84e-1)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (6.14e-2)" 0.4 0.3 1.2 6.2 0.6 0.9 0.8 1.2 1.8 0.1 2.7 1.9 1.9 0.2 0.2 0.4 0.3 0.4 0.2 1.1 1.1 5.1 20.6 0.8 18.7 1.8 1.2 0.5 0.2 0.0 0.0 0.1 1.7 0.3 1.5 0.3 1.3 0.2 0.3 0.5 2.3 0.1 0.1 2.7 2.6 0.4 0.7 0.5 2.1 0.0 22.9 1.6 0.1 3.7 0.1 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.0 0.0 1.0 0.3 116.5 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.2 0.3 1.1 0.0 0.2 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 38.6 0.0 0.1 2.4 0.2 0.1 0.3 0.0 1.1 0.2 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.3 0.6 0.0 0.1 0.3 0.1 0.1 15.2 1.4 84.8 0.2 0.2 0.0 1.0 0.4 0.2 4.0 0.3 0.5 1.6 1.8 2.6 0.1 0.6 0.3 1.0 0.8 0.5 0.1 0.3 0.1 0.5 1.2 0.6 1.2 1.8 1.1 1.1 1.8 1.2 1.7 0.1 0.7 3.7 0.2 0.0 2.2 0.0 5.0 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.7 0.0 3.7 1.8 0.0 0.0 2.2 0.0 1.9 0.0 1.1 0.1 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.5 3.1 0.1 1.3 0.0 0.0 15.7 0.0 0.0 0.5 0.0 0.0 0.6 1.1 1.5 0.0 0.4 0.0 0.0 0.1 0.1 2.1 0.5 0.2 0.0 0.0 0.0 35.1 0.2 0.0 7.8 0.0 0.3 0.0 0.4 0.3 0.1 0.0 0.0 1.0 0.0 4.6 0.1 0.0 0.3 NWD2 KIAA1239 ENSG00000174145 "NACHT and WD repeat domain containing 2" Q9ULI1 4 37244743-37449463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.4;brain: 5.9" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 91.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046911 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046911: AB_2679861" "unprognostic (1.14e-2)" "unprognostic (3.12e-2)" "unprognostic (2.53e-1)" "unprognostic (5.47e-2)" "unprognostic (9.42e-2)" "unprognostic (2.55e-1)" "unprognostic (5.15e-2)" "unprognostic (1.63e-2)" "unprognostic (7.47e-2)" "unprognostic (1.00e-1)" "unprognostic (7.00e-2)" "unprognostic (1.98e-1)" "unprognostic (1.86e-2)" "unprognostic (7.65e-2)" "unprognostic (4.36e-2)" "unprognostic (1.26e-2)" 2.4 0.0 1.0 0.0 5.9 0.0 1.1 0.0 2.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.0 0.1 0.0 0.0 0.2 4.7 0.0 0.1 0.0 0.1 0.0 2.5 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.9 0.0 2.7 1.6 1.1 0.2 4.7 2.5 0.0 0.1 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.1 0.0 4.5 1.9 0.1 2.5 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 NXNL1 "RDCVF, TXNL6" ENSG00000171773 "Nucleoredoxin like 1" Q96CM4 19 17455425-17460926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "choroid plexus: 16.2;retina: 64.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Cone photoreceptor cells: 52.1;Muller glia cells: 21.0;Rod photoreceptor cells: 109.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (2.62e-1)" "unprognostic (5.49e-1)" "unprognostic (1.81e-1)" "unprognostic (3.63e-1)" "unprognostic (1.13e-1)" 2.0 1.4 1.1 0.1 1.2 0.2 0.8 1.9 1.3 0.1 16.2 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.4 2.5 0.8 0.1 0.0 0.1 0.2 1.7 1.2 0.3 0.0 0.1 0.0 0.1 1.4 0.2 0.1 64.4 0.4 0.0 0.6 0.6 0.1 0.1 1.1 0.1 0.1 0.3 1.6 0.1 0.3 0.5 0.1 0.1 0.0 1.3 0.2 0.5 0.3 0.4 0.5 0.3 0.2 0.1 0.0 0.5 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.2 0.2 0.3 0.0 0.2 0.3 0.2 0.1 0.4 0.4 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 0.4 0.2 0.5 0.0 0.6 0.1 0.2 0.1 0.1 0.2 0.2 0.5 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.4 0.3 0.1 0.1 0.0 0.0 0.2 0.3 0.1 0.3 0.4 0.4 0.0 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.0 1.1 1.2 1.9 1.3 2.5 0.8 1.7 1.2 1.4 1.1 1.6 1.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.4 0.0 0.0 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 21.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 109.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 NXNL2 "C9orf121, RdCVF2" ENSG00000130045 "Nucleoredoxin like 2" Q5VZ03 9 88534033-88584274 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 11.4;Endometrial ciliated cells: 39.1;Glandular and luminal cells: 13.9;Granulosa cells: 13.2;Proximal tubular cells: 18.6;Theca cells: 12.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 7.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 10.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045526 Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA045526: AB_10961044" "prognostic favorable (6.53e-4)" "unprognostic (9.70e-2)" "unprognostic (4.78e-3)" "prognostic favorable (3.83e-8)" "unprognostic (2.70e-2)" "unprognostic (3.19e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-4)" "unprognostic (1.92e-2)" "unprognostic (1.69e-1)" "unprognostic (2.62e-3)" "unprognostic (5.58e-2)" "prognostic favorable (9.60e-4)" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-2)" 6.5 0.7 4.3 1.2 3.4 4.2 2.8 6.0 5.5 4.0 1.8 0.5 0.9 2.0 1.3 0.4 4.3 1.0 0.7 3.4 3.4 2.3 4.5 0.7 0.9 0.7 1.2 1.1 0.4 0.3 0.1 0.6 1.4 0.9 0.4 4.8 1.6 0.7 1.3 1.5 0.9 0.4 0.4 1.1 0.8 1.3 3.6 0.5 1.3 0.1 0.5 0.4 0.3 5.1 1.5 2.6 1.0 1.0 0.1 0.7 0.7 2.6 0.7 0.3 0.5 0.6 1.0 0.6 1.1 0.3 0.7 1.3 0.4 0.1 0.9 0.4 0.8 1.3 4.0 1.0 0.4 0.7 1.1 0.5 0.2 0.3 0.2 0.4 0.0 0.9 0.9 2.7 0.7 0.7 0.7 1.2 1.4 0.5 0.7 0.5 0.5 0.9 10.4 0.8 0.6 0.4 1.6 0.8 0.5 0.7 1.2 0.6 0.9 0.9 1.9 1.5 0.6 0.9 0.8 0.7 0.7 0.9 0.7 2.1 0.3 0.8 0.6 0.1 0.6 0.2 0.3 0.7 0.0 0.3 0.6 0.7 0.8 0.5 0.1 0.3 0.6 0.3 4.3 3.4 6.0 5.5 3.4 3.4 0.7 1.2 1.4 0.4 3.6 5.1 0.2 0.0 0.0 1.3 0.1 0.0 1.9 0.7 1.2 0.2 7.5 3.2 0.3 4.3 0.1 1.8 0.0 0.2 0.0 0.0 1.9 0.8 11.4 39.1 4.3 0.8 0.0 0.0 1.2 0.2 1.3 0.8 0.0 13.9 0.0 13.2 0.0 0.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 4.4 0.9 0.2 0.0 0.0 0.0 0.5 0.0 1.0 0.7 0.2 0.0 2.2 0.1 0.4 0.0 18.6 0.2 0.8 0.0 0.3 1.3 0.4 1.6 0.0 0.1 1.1 0.3 12.7 0.0 2.2 NXPE4 "C11orf33, FAM55D, FLJ20127" ENSG00000137634 "Neurexophilin and PC-esterase domain family member 4" Q6UWF7 11 114570591-114595786 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 119.6;salivary gland: 77.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 95.5;Intestinal goblet cells: 88.1;Paneth cells: 41.8;Undifferentiated cells: 115.8" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 13.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042801 Approved "Secreted to digestive system" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA042801: AB_10793986" "unprognostic (1.35e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-3)" "unprognostic (1.27e-1)" "unprognostic (3.51e-3)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (7.47e-3)" "unprognostic (4.36e-2)" "unprognostic (2.05e-1)" 0.1 0.0 0.1 7.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 114.2 0.6 0.2 6.8 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 5.3 119.6 0.0 77.2 0.2 0.0 0.0 0.7 5.2 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 0.0 0.0 0.5 0.0 0.0 0.0 17.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 41.8 0.0 0.1 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 115.8 0.2 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.9;Fibroblasts: 135.9;Hepatocytes: 218.8;Muller glia cells: 279.4;Theca cells: 149.0;Urothelial cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 115.5;Hep G2: 190.1;NB-4: 139.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" 66.0 91.5 47.7 18.0 56.8 10.8 42.6 35.8 57.1 66.7 40.5 61.9 47.7 54.2 16.0 22.8 54.6 34.5 55.1 48.1 36.5 51.4 396.6 19.2 5.8 39.0 37.8 61.0 74.1 6.7 27.4 8.1 37.1 33.5 36.5 30.7 53.9 13.7 13.2 12.0 57.3 29.1 35.9 54.4 33.5 3.7 45.0 4.6 25.9 12.2 3.7 42.6 40.4 44.6 24.9 7.5 30.9 14.4 47.8 53.4 1.7 47.7 53.8 20.5 30.0 7.5 37.3 0.0 115.5 35.6 33.7 25.7 8.9 13.2 8.2 18.7 21.1 21.1 4.7 190.1 42.4 46.7 7.9 66.8 7.9 19.8 54.8 39.9 59.7 12.7 14.0 22.7 5.0 9.4 0.3 139.9 11.6 7.3 40.8 11.8 0.9 23.7 31.8 13.4 1.5 10.0 14.0 15.2 40.2 8.6 4.8 74.7 32.7 39.3 14.7 40.8 4.6 0.8 0.7 0.4 30.3 76.2 14.1 0.0 3.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.1 0.0 0.3 0.5 0.1 0.8 47.7 56.8 35.8 57.1 48.1 36.5 39.0 37.8 37.1 35.9 45.0 44.6 19.4 0.0 0.6 102.2 3.7 9.4 33.6 7.3 12.5 3.2 6.0 7.0 5.5 34.3 3.5 71.7 2.1 2.1 1.1 135.9 27.4 14.8 0.2 4.7 70.9 40.0 22.8 12.8 0.6 28.7 5.5 135.9 11.7 12.2 1.3 2.6 12.5 218.8 6.0 0.0 2.3 56.5 4.1 11.5 20.9 1.1 16.8 11.0 16.0 23.4 10.2 279.4 0.0 5.5 11.0 28.2 56.5 4.5 14.5 31.3 111.1 79.3 0.4 10.6 52.6 8.6 40.8 0.7 6.9 11.3 10.2 6.2 3.1 149.0 45.8 192.5 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OR2I1P "HS6M1-14, OR2I1, OR2I2, OR2I3P, OR2I4P" ENSG00000237988 "Olfactory receptor family 2 subfamily I member 1 pseudogene" 6 29550407-29557721 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Ductal cells: 1.0;granulocytes: 1.3;monocytes: 1.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 3: Monocytes - Immune response regulation" "unprognostic (7.45e-3)" "unprognostic (1.69e-2)" "unprognostic (6.00e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.60e-2)" "unprognostic (1.07e-3)" "unprognostic (3.29e-1)" "unprognostic (2.23e-1)" "unprognostic (5.34e-3)" "prognostic favorable (5.58e-4)" "unprognostic (1.32e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (4.00e-6)" "unprognostic (8.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.5" "Cell type enhanced" "Detected in many" "Early spermatids: 251.6;Late spermatids: 328.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 427.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (6.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.96e-1)" "prognostic favorable (9.29e-4)" "unprognostic (1.26e-1)" "unprognostic (3.67e-1)" "unprognostic (5.68e-2)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.37e-1)" "unprognostic (4.55e-1)" "unprognostic (1.09e-3)" "prognostic favorable (5.18e-4)" 149.0 29.6 39.6 33.9 39.5 39.7 70.8 37.2 45.8 40.1 55.9 41.9 50.0 36.1 64.7 28.4 28.0 32.4 63.0 41.7 40.2 38.0 234.5 49.0 55.9 40.9 38.6 39.9 109.6 51.1 50.2 35.5 38.3 46.9 38.6 25.1 70.4 41.6 44.2 41.4 47.8 36.6 40.1 38.3 50.0 50.8 41.6 79.4 57.7 29.5 56.4 46.9 26.3 39.1 33.5 40.2 41.8 34.8 106.1 40.2 37.9 48.0 55.4 50.5 48.4 46.1 36.3 24.7 44.6 59.4 34.5 56.0 29.8 38.6 46.9 427.6 53.2 24.1 22.5 113.0 41.5 28.5 40.6 44.2 39.7 34.9 19.7 57.2 22.8 68.5 30.9 194.8 28.0 30.1 85.1 31.9 23.4 44.2 20.1 71.2 37.7 78.4 28.2 80.1 36.6 37.2 31.8 196.6 32.9 46.3 70.8 30.8 18.7 27.4 34.0 23.6 36.8 104.2 95.3 34.5 28.2 27.6 20.6 9.3 4.7 61.1 39.4 7.7 28.3 26.4 39.3 43.3 4.2 23.1 44.2 53.7 7.7 18.4 11.6 21.1 27.7 36.6 39.6 39.5 37.2 45.8 41.7 40.2 40.9 38.6 38.3 40.1 41.6 39.1 7.6 51.3 37.2 2.9 28.7 16.4 13.7 13.1 21.6 18.5 25.9 14.5 28.9 17.2 15.3 42.3 0.0 25.9 18.4 27.3 3.9 18.4 251.6 7.2 12.6 10.3 25.9 34.1 3.4 29.2 17.9 13.9 11.2 13.8 18.4 10.5 7.5 97.8 8.3 13.5 3.8 26.8 18.3 7.5 13.0 328.9 18.6 6.0 16.0 1.9 22.1 44.9 57.7 3.5 3.2 38.8 20.8 28.6 41.2 15.2 29.2 11.9 8.0 11.2 26.3 8.5 16.5 5.8 7.6 11.5 14.3 9.3 35.6 21.0 17.7 12.4 OSBPL1A "ORP-1, ORP1, OSBPL1B" ENSG00000141447 "Oxysterol binding protein like 1A" Q9BXW6 18 24162045-24397880 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 214.3;Oligodendrocytes: 433.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 22 "basophil: 93.4" "Lineage enriched" "Detected in many" 22 "granulocytes: 93.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040959, HPA043401" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040959: AB_10964295, HPA043401: AB_10960208" "unprognostic (1.75e-2)" "unprognostic (3.35e-2)" "unprognostic (9.84e-3)" "unprognostic (4.92e-3)" "unprognostic (2.34e-1)" "unprognostic (3.06e-2)" "unprognostic (5.82e-2)" "unprognostic (2.06e-1)" "unprognostic (5.88e-2)" "unprognostic (2.62e-2)" "unprognostic (2.41e-1)" "unprognostic (8.53e-2)" "prognostic favorable (4.98e-13)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.18e-2)" "unprognostic (5.42e-3)" "unprognostic (1.56e-1)" 72.0 27.8 77.1 9.4 105.6 15.4 47.9 99.6 136.0 52.4 114.0 34.9 20.7 48.0 17.2 30.8 29.6 21.1 52.0 77.3 90.6 43.5 13.3 24.2 10.4 89.7 95.0 27.3 16.5 62.8 18.7 8.3 94.5 23.0 22.7 82.2 51.5 26.2 170.9 17.5 20.2 41.1 79.2 9.9 21.3 14.3 91.3 9.6 29.0 123.1 7.9 25.4 20.0 136.8 38.2 11.4 26.3 49.1 60.0 48.7 24.5 14.0 40.4 12.4 10.2 7.1 38.9 0.1 16.0 25.1 19.7 37.9 10.4 24.4 11.4 0.2 19.6 12.1 7.8 0.2 29.9 30.4 6.0 63.4 34.4 9.5 38.4 54.0 15.9 10.4 0.0 0.3 15.5 16.1 7.0 9.1 21.7 19.5 36.8 0.0 21.0 3.2 3.3 27.7 16.9 16.6 32.6 37.5 46.1 24.5 13.7 21.7 3.4 45.9 9.4 14.9 13.6 0.4 5.3 1.0 22.3 8.7 26.8 93.4 4.2 1.1 0.2 2.2 0.1 0.0 0.8 0.6 4.1 0.4 0.6 0.5 1.6 0.2 0.7 4.1 0.8 1.5 77.1 105.6 99.6 136.0 77.3 90.6 89.7 95.0 94.5 79.2 91.3 136.8 214.3 16.0 21.6 142.0 5.4 20.1 43.4 16.6 29.6 66.6 73.6 64.3 78.0 41.5 20.0 20.2 22.9 12.1 11.1 23.6 64.6 13.3 67.7 27.6 55.3 89.9 4.8 18.7 180.3 7.4 8.1 59.9 16.3 17.0 17.2 137.9 37.5 12.4 26.6 25.2 166.4 40.0 40.7 27.4 17.9 76.4 42.9 34.3 58.7 67.5 11.0 124.8 0.0 75.9 433.0 10.7 19.1 54.9 2.5 27.1 29.8 71.7 21.7 112.3 32.9 44.7 65.8 6.7 9.9 27.2 10.2 6.4 3.8 103.7 16.2 26.4 OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 166.1;endometrium 1: 155.1;fallopian tube: 155.3" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 243.1;Leydig cells: 784.1;Peritubular cells: 758.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 16 "ASC diff: 542.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA052425: AB_2681826, HPA063486: AB_2685022" "unprognostic (1.72e-1)" "unprognostic (1.92e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "prognostic favorable (2.44e-5)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.73e-3)" "unprognostic (3.01e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-7)" "unprognostic (1.37e-2)" "unprognostic (2.39e-1)" "unprognostic (2.56e-4)" "unprognostic (8.54e-3)" 45.0 9.9 0.0 2.4 0.0 0.6 26.0 0.2 0.2 166.1 0.0 9.2 0.6 155.1 53.7 15.1 155.3 12.9 4.2 0.0 0.0 1.3 0.3 3.6 2.4 0.0 0.0 93.2 4.2 3.0 2.7 8.2 0.0 40.2 3.8 0.0 6.8 72.2 5.6 27.9 24.9 47.1 0.0 0.2 5.1 35.6 0.0 0.8 5.6 5.1 1.1 27.2 83.8 0.0 32.3 4.5 0.0 4.4 542.4 17.2 4.3 17.6 33.1 13.7 13.6 3.4 3.9 0.0 2.9 26.7 0.8 12.4 2.7 4.7 6.7 1.5 13.0 0.6 3.3 1.6 8.9 0.9 0.6 17.0 9.8 2.3 1.6 0.8 0.0 4.8 4.0 0.4 0.6 14.6 2.9 5.7 0.0 2.6 2.8 13.8 1.6 1.1 1.1 2.7 1.4 0.1 1.9 7.5 0.4 0.3 4.3 7.5 0.2 2.1 0.1 13.9 1.0 0.7 0.5 0.3 0.9 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.9 14.1 6.6 3.4 1.2 0.0 7.9 5.3 0.7 0.0 3.3 0.0 0.0 17.2 0.9 0.7 0.0 0.0 5.8 7.8 243.1 3.7 0.0 0.0 0.0 0.0 138.4 71.7 0.5 5.9 0.0 0.2 0.0 0.0 9.3 0.0 0.0 18.4 10.2 1.9 21.9 24.1 784.1 2.7 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 758.3 4.6 3.6 103.9 0.1 1.7 0.0 32.9 8.8 21.3 5.1 4.5 0.3 9.1 24.2 2.3 95.6 22.3 2.2 OSTF1 "bA235O14.1, OSF, SH3P2" ENSG00000134996 "Osteoclast stimulating factor 1" Q92882 9 75088514-75147265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 329.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 302.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020514 Approved Supported Cytosol NA NA 580000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA020514: AB_2670461" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (7.54e-2)" "prognostic favorable (3.67e-5)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-3)" "unprognostic (3.76e-1)" "unprognostic (7.89e-2)" "unprognostic (6.36e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" 44.3 36.9 27.8 65.7 35.0 56.3 34.9 32.0 37.2 34.1 25.4 42.5 38.2 22.7 38.2 104.8 20.0 42.8 32.0 28.3 33.2 34.6 57.7 56.4 74.9 31.0 32.5 16.0 19.4 72.1 19.1 69.9 33.1 22.7 45.8 12.3 38.5 19.6 9.5 63.1 47.8 28.8 30.8 87.0 40.6 18.0 31.0 47.8 29.0 16.0 85.0 55.3 53.9 35.1 69.1 16.0 7.7 11.2 45.4 41.7 81.3 71.9 46.9 26.9 24.4 8.2 50.8 70.9 35.3 59.2 34.6 111.8 12.9 51.9 77.0 302.0 16.0 39.3 24.8 42.5 36.7 71.5 141.6 29.1 49.2 31.6 21.8 23.7 91.2 59.4 13.4 158.4 65.4 35.9 107.5 44.8 14.5 161.5 30.8 20.1 52.3 63.0 57.0 97.1 6.5 0.6 53.1 74.1 36.2 58.2 97.4 79.9 86.4 55.8 19.4 108.3 30.8 30.1 52.5 26.7 67.1 81.9 46.4 359.5 177.7 464.8 158.6 199.3 169.6 101.2 110.5 131.5 148.7 87.4 62.1 109.8 495.2 168.4 256.8 110.6 163.0 283.0 27.8 35.0 32.0 37.2 28.3 33.2 31.0 32.5 33.1 30.8 31.0 35.1 113.4 22.4 24.4 8.1 90.8 82.2 61.2 78.2 61.5 2.9 38.6 23.2 7.8 28.6 51.2 33.1 6.2 125.5 162.1 64.8 76.3 49.7 11.9 42.8 59.4 60.5 27.2 23.3 32.0 52.3 252.9 42.1 31.1 51.1 137.6 4.2 71.7 32.2 233.1 10.1 12.6 31.9 69.2 167.4 181.5 6.0 23.9 155.7 76.5 43.1 329.9 6.0 268.8 30.2 67.3 60.5 97.7 15.4 83.2 34.1 64.1 63.0 27.3 8.6 19.7 15.9 45.0 6.7 17.8 141.4 114.5 133.9 163.8 37.6 38.2 91.6 OTX1 ENSG00000115507 "Orthodenticle homeobox 1" P32242 2 63050057-63057836 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "salivary gland: 18.0;skin 1: 8.4" "Cell type enhanced" "Detected in some" "Astrocytes: 9.8;Basal respiratory cells: 6.3;Club cells: 4.1;Ionocytes: 6.1;Respiratory ciliated cells: 6.8;Suprabasal keratinocytes: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 95 "neutrophil: 9.4" "Lineage enriched" "Detected in single" 95 "granulocytes: 9.4" "Cell line enriched" "Detected in many" 9 "THP-1: 54.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052122 Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA052122: AB_2681736" "unprognostic (2.25e-2)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.36e-3)" "unprognostic (2.32e-1)" "unprognostic (1.67e-2)" "unprognostic (6.92e-3)" "unprognostic (3.66e-2)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (2.26e-3)" "unprognostic (1.71e-1)" "unprognostic (0.00e+0)" "unprognostic (4.64e-2)" "unprognostic (2.31e-1)" "unprognostic (3.80e-4)" "unprognostic (3.67e-3)" 0.1 0.0 2.1 0.0 1.7 0.0 0.2 0.1 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.1 0.0 0.2 2.5 0.0 0.2 0.0 0.0 0.0 0.7 0.7 0.0 0.0 18.0 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.2 0.3 2.8 0.0 0.0 0.0 0.5 0.0 0.1 1.8 2.3 1.3 4.2 2.5 0.0 0.1 5.9 0.0 0.3 0.3 0.4 4.4 2.2 0.1 0.8 0.0 1.1 3.0 2.7 1.9 0.5 1.1 2.5 2.7 2.2 5.0 0.0 1.9 2.0 0.0 0.7 0.0 0.7 0.8 0.0 2.6 2.4 0.0 0.2 2.1 2.6 4.6 0.0 2.2 1.6 2.3 3.6 0.7 1.2 0.8 0.4 0.5 1.8 0.2 1.5 0.0 1.0 54.1 0.1 0.9 1.7 0.0 0.9 1.5 1.1 4.0 0.3 2.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 2.1 1.7 0.1 2.5 1.9 1.4 0.2 2.5 0.7 0.0 2.8 1.8 0.2 0.0 0.0 9.8 0.1 1.7 0.0 6.3 0.6 0.0 0.8 1.0 0.8 0.0 4.1 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.2 0.6 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 6.8 0.0 0.0 0.7 0.3 0.3 0.5 1.1 2.6 0.1 0.0 0.1 0.2 0.1 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 243.7;Distal tubular cells: 187.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 238.7;SiHa: 319.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 52.7 15.8 30.4 16.6 34.9 13.3 18.5 23.9 32.7 13.5 15.9 19.2 8.3 14.9 17.6 26.8 12.4 15.2 245.9 36.2 27.1 53.1 1.3 8.0 21.7 19.5 21.4 13.8 5.3 48.6 14.7 5.0 20.0 25.5 21.1 23.6 18.9 29.8 28.5 23.1 12.8 36.6 19.3 11.0 34.2 13.2 25.7 76.8 27.3 42.6 25.9 15.1 13.8 24.5 35.3 1.6 27.9 33.6 84.7 45.0 0.1 62.1 38.9 50.3 30.4 5.7 23.5 91.2 15.0 47.5 25.8 20.5 77.5 55.9 58.5 78.5 9.1 63.9 238.7 11.9 36.8 125.8 20.9 42.7 15.3 49.3 82.2 24.6 46.4 81.6 13.3 114.0 58.1 4.5 105.5 6.1 6.4 0.0 24.5 82.8 78.9 68.7 41.7 2.9 27.9 28.8 319.5 0.3 38.3 2.5 0.4 27.4 28.3 39.7 51.9 68.6 50.6 18.6 16.5 3.6 59.9 90.9 30.9 1.4 1.4 4.7 11.6 1.5 13.8 10.0 11.5 12.7 6.3 7.5 13.6 10.9 0.4 11.3 2.5 2.4 21.5 6.6 30.4 34.9 23.9 32.7 36.2 27.1 19.5 21.4 20.0 19.3 25.7 24.5 8.4 6.4 9.2 37.5 19.2 14.8 11.7 12.4 17.6 14.1 18.8 14.2 243.7 7.2 14.3 11.0 2.1 7.0 18.3 5.0 187.9 5.4 19.1 11.7 18.8 9.8 13.2 23.1 71.5 0.7 11.9 21.3 20.4 31.2 9.5 8.7 6.8 0.3 38.2 13.5 84.2 18.6 12.2 1.3 7.0 8.6 6.2 5.2 16.0 26.2 4.4 11.8 10.3 66.4 46.8 4.8 5.3 7.5 31.3 12.1 2.9 27.4 5.6 21.6 13.1 9.7 24.6 35.6 19.7 27.6 21.6 6.8 26.6 8.6 18.1 9.0 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "Extravillous trophoblasts: 49.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cell line enhanced" "Detected in some" "RT4: 3.3;SK-BR-3: 1.4;U-2 OS: 1.6" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 1.3 0.0 1.0 1.3 0.8 0.1 4.2 0.5 1.5 1.0 0.5 2.0 0.2 0.5 2.5 2.1 1.6 0.1 0.2 0.8 2.1 4.0 0.0 0.4 0.1 1.2 1.3 0.1 0.5 0.3 0.3 0.9 1.0 0.5 1.6 0.0 3.0 0.4 0.2 2.6 0.4 0.5 0.7 0.4 0.2 0.1 2.6 0.3 0.5 0.3 0.8 1.7 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.1 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 1.0 0.8 0.5 1.5 0.8 2.1 1.2 1.3 1.0 0.7 2.6 1.3 0.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 1.7 1.4 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.2 1.9 0.0 0.2 0.7 0.1 0.8 1.2 0.0 0.6 0.0 49.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.5 0.0 0.0 0.4 0.1 0.0 0.3 3.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.9 0.0 0.0 2.2 0.0 3.7 0.0 0.0 1.2 0.0 P2RX5 "LRH-1, P2X5" ENSG00000083454 "Purinergic receptor P2X 5" Q93086 17 3672199-3696240 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.7;lymphoid tissue: 78.2" "Group enriched" "Detected in some" 4 "B-cells: 94.6;Plasma cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "memory B-cell: 76.4;naive B-cell: 84.8" "Lineage enriched" "Detected in many" 20 "B-cells: 84.8" "Cell line enhanced" "Detected in many" "Daudi: 53.2;Karpas-707: 32.7;RPMI-8226: 59.5;U-698: 47.1" "HPA021948, HPA067827" Supported Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA021948: AB_1854878, HPA067827: AB_2685908" "unprognostic (1.08e-3)" "unprognostic (9.16e-2)" "unprognostic (1.40e-2)" "unprognostic (5.81e-2)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (8.33e-2)" "unprognostic (4.34e-1)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.99e-8)" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (3.50e-2)" "unprognostic (3.63e-2)" 0.8 0.3 1.8 30.4 2.2 9.4 0.8 0.2 2.7 0.3 0.0 2.4 1.5 0.1 0.0 0.7 0.3 1.3 8.0 2.1 0.9 0.7 0.5 1.4 78.2 0.6 0.5 0.0 0.2 0.2 1.2 0.2 0.7 0.5 1.9 0.4 1.8 0.0 17.5 0.0 24.7 0.5 0.1 54.4 3.4 0.7 1.1 12.1 0.9 4.0 53.9 2.7 0.3 1.4 8.3 6.7 0.0 0.0 0.2 1.3 0.0 8.4 3.9 0.9 2.6 5.5 9.8 53.2 4.9 4.2 2.9 4.3 18.8 0.0 1.7 0.9 3.2 2.7 17.5 6.3 1.2 3.6 4.2 2.1 1.8 0.2 12.4 6.5 0.0 12.2 0.5 32.7 18.2 0.0 23.4 8.1 4.9 4.4 20.5 0.8 0.0 59.5 0.2 6.3 4.3 0.0 7.5 2.5 3.9 0.0 2.0 3.3 0.1 0.0 4.5 0.2 1.5 11.0 25.2 47.1 0.0 5.1 0.5 0.0 0.1 2.0 3.1 0.0 4.2 76.4 2.8 2.2 0.4 84.8 0.3 0.3 0.0 0.0 0.0 0.1 1.9 4.5 1.8 2.2 0.2 2.7 2.1 0.9 0.6 0.5 0.7 0.1 1.1 1.4 0.1 0.0 0.6 0.0 94.6 0.4 0.1 0.0 0.0 0.8 0.1 0.1 2.7 0.0 0.0 1.8 0.0 0.0 13.4 0.0 0.0 0.2 4.8 0.2 0.2 0.7 0.0 11.1 0.0 0.2 0.0 0.3 0.5 0.3 4.5 0.0 1.4 0.4 0.2 0.0 0.0 0.1 0.0 1.2 0.0 3.1 1.5 1.6 3.6 0.0 1.1 0.0 2.1 0.0 0.0 1.5 0.0 0.0 29.7 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.9 1.0 0.8 0.0 0.0 0.0 11.0 0.0 0.1 0.1 P2RY10 P2Y10 ENSG00000078589 "P2Y receptor family member 10" O00398 X 78945332-78963727 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4" "Cell type enhanced" "Detected in some" "B-cells: 79.3;granulocytes: 29.2;Langerhans cells: 38.5;monocytes: 32.5;Plasma cells: 32.6;T-cells: 55.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "basophil: 256.1" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "Karpas-707: 121.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036757, HPA065766" Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA036757: AB_10696786, HPA065766: AB_2685556" "unprognostic (3.02e-3)" "unprognostic (1.47e-3)" "unprognostic (1.50e-6)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.13e-4)" "unprognostic (3.33e-2)" "unprognostic (8.30e-2)" "unprognostic (1.13e-2)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (2.23e-1)" "unprognostic (6.54e-2)" "unprognostic (3.85e-2)" "unprognostic (3.99e-2)" 0.8 0.5 0.4 14.6 0.5 8.2 0.9 1.4 1.1 1.0 0.0 2.7 3.1 0.8 0.3 1.1 0.4 3.2 0.4 0.4 0.1 0.4 1.6 2.4 27.4 0.2 0.0 0.4 1.5 0.0 0.1 0.3 0.2 1.3 3.6 0.6 1.2 0.2 0.2 0.6 6.4 0.7 0.0 16.6 3.9 0.3 0.2 10.3 0.6 0.1 25.8 5.4 0.4 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.3 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 121.8 0.0 0.1 0.2 0.2 0.2 0.0 0.2 0.2 0.2 9.9 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.1 0.0 26.5 0.1 1.4 0.2 0.3 0.1 256.1 0.2 158.1 12.6 0.9 11.4 73.1 28.0 25.5 4.0 74.1 25.7 19.5 27.9 18.1 10.9 2.8 41.7 13.2 0.4 0.5 1.4 1.1 0.4 0.1 0.2 0.0 0.2 0.0 0.2 0.5 0.7 0.0 1.7 0.0 79.3 1.8 0.0 0.0 0.0 0.0 0.3 0.3 1.2 0.0 0.6 0.0 0.0 0.0 15.0 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.8 0.5 0.1 29.2 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.6 38.5 0.0 0.0 3.6 8.8 0.0 32.5 0.0 9.2 0.0 0.0 0.0 0.0 0.0 32.6 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 2.0 0.0 55.1 0.0 0.0 0.3 PALM "KIAA0270, PALM1" ENSG00000099864 Paralemmin O75781 19 708935-748329 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 257.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.2;Distal tubular cells: 52.8;Hepatic stellate cells: 63.1;Leydig cells: 48.4;Muller glia cells: 92.8;Proximal tubular cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.9" "Lineage enriched" "Detected in single" 19 "monocytes: 1.9" "Cell line enhanced" "Detected in many" "AN3-CA: 16.6;EFO-21: 20.7;REH: 34.3;SH-SY5Y: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041713, HPA049578" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA041713: AB_10794305, HPA049578: AB_2680822" "unprognostic (9.08e-3)" "unprognostic (2.97e-2)" "unprognostic (2.11e-2)" "unprognostic (3.53e-3)" "unprognostic (1.61e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-1)" "unprognostic (8.39e-2)" "unprognostic (7.62e-2)" "unprognostic (1.36e-2)" "prognostic favorable (9.81e-4)" "unprognostic (2.74e-2)" "prognostic favorable (5.44e-4)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (6.00e-2)" 89.0 23.1 158.4 2.0 140.7 0.7 66.0 86.1 257.8 60.3 54.5 54.4 7.4 43.3 3.3 14.4 47.0 2.8 41.1 165.1 97.0 52.7 7.3 30.0 0.6 106.4 103.6 65.7 5.8 1.2 62.5 6.6 96.9 42.6 0.6 4.6 12.9 8.3 9.6 33.4 20.8 2.4 95.0 23.4 18.0 19.6 112.1 0.6 21.0 1.7 0.2 29.4 41.8 110.5 0.0 7.6 14.6 16.6 0.6 0.2 2.2 0.9 0.0 1.0 0.2 1.9 0.1 0.0 20.7 0.0 0.0 2.7 8.0 0.0 0.4 0.0 14.1 0.0 4.3 9.3 9.4 0.0 0.3 3.0 0.0 0.9 0.0 0.4 0.4 1.6 4.6 0.1 1.1 15.9 1.1 9.4 5.9 1.0 3.2 34.3 0.0 0.2 0.6 0.0 1.7 28.0 7.5 0.1 0.2 4.6 1.8 4.5 0.0 0.0 13.4 16.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 158.4 140.7 86.1 257.8 165.1 97.0 106.4 103.6 96.9 95.0 112.1 110.5 27.2 0.0 1.7 85.2 2.7 7.1 7.2 6.3 1.8 11.4 5.7 5.3 5.8 1.5 4.9 5.5 12.5 0.9 0.2 1.3 52.8 1.4 1.4 3.8 27.0 25.6 0.0 1.3 26.9 0.2 7.2 37.6 1.1 5.9 0.0 1.4 63.1 0.4 1.0 25.2 15.1 0.1 12.2 2.4 5.4 6.6 48.4 1.1 17.8 10.3 0.1 92.8 0.0 16.6 9.8 0.2 1.4 45.1 0.1 10.1 7.2 57.9 0.5 5.7 0.0 2.3 14.1 0.8 7.3 1.1 7.0 1.9 1.1 0.1 0.4 7.2 PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103031105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1560.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1406.5;Enteroendocrine cells: 321.4;Inhibitory neurons: 487.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 529.9;fHDF/TERT166: 714.5;hTERT-RPE1: 562.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA 98000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: AB_2677919" "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" 119.3 202.5 71.6 34.6 81.4 10.1 99.0 50.7 82.5 595.0 96.2 125.1 52.6 140.9 678.2 69.4 87.6 97.3 1560.4 75.2 179.9 116.0 20.1 88.3 27.7 86.5 99.8 136.4 104.4 257.8 137.0 60.0 170.9 91.6 80.4 37.6 205.4 236.5 155.3 66.9 52.1 157.9 55.7 52.5 131.6 22.4 106.0 17.9 95.1 159.4 30.5 103.3 116.1 50.0 111.3 16.3 195.9 87.2 529.9 314.8 78.0 307.6 457.0 89.1 268.9 53.5 143.2 0.1 65.0 714.5 125.7 36.8 11.0 135.3 244.0 13.5 44.7 22.9 60.0 17.7 80.3 7.4 23.9 173.4 57.3 65.6 49.2 562.6 186.8 8.9 0.9 15.0 255.6 22.9 0.1 3.2 35.3 19.7 59.3 8.5 108.9 62.4 346.1 13.0 92.3 63.9 131.2 8.3 83.3 114.0 34.0 7.3 144.9 280.8 72.4 133.3 93.4 33.1 8.6 0.4 322.3 30.8 247.6 4.2 8.0 0.2 20.7 1.5 14.9 0.8 12.3 15.6 3.1 0.4 4.1 6.8 16.6 26.3 3.4 1.6 19.9 10.8 71.6 81.4 50.7 82.5 75.2 179.9 86.5 99.8 170.9 55.7 106.0 50.0 45.7 54.5 39.3 47.0 3.9 28.2 12.0 26.1 12.0 19.1 27.5 12.1 1406.5 0.0 30.4 60.7 2.1 1.6 12.6 13.7 7.9 12.6 8.8 47.6 48.6 63.5 321.4 3.4 229.2 21.5 40.6 220.4 26.0 83.0 9.5 68.3 74.6 3.5 5.9 8.4 487.7 13.8 18.3 10.3 48.3 8.1 60.3 9.3 37.4 192.0 9.5 11.6 22.6 154.8 9.3 30.6 6.3 58.6 12.1 26.4 4.8 43.8 19.2 3.8 19.7 36.4 44.9 2.6 5.6 8.0 23.7 6.7 16.6 19.3 6.3 18.2 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 119.8;Endometrial stromal cells: 37.9;Leydig cells: 34.5;Peritubular cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 7 "dendritic cells: 5.4;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "HHSteC: 16.1;HSkMC: 30.6;hTCEpi: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048682, HPA053453" Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 76000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA048682: AB_2680492, HPA053453: AB_2682155" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" 16.1 6.6 15.7 8.4 17.0 2.3 10.7 12.1 23.5 30.3 15.7 13.4 3.0 20.4 14.9 7.1 23.0 5.6 8.0 14.4 13.3 42.6 3.2 13.4 15.2 14.1 14.6 16.8 4.0 0.4 16.4 4.0 13.1 13.6 4.5 9.5 7.5 7.5 2.1 15.7 17.8 6.3 12.3 29.1 11.3 6.4 14.4 5.1 24.8 1.8 13.6 5.1 9.1 12.3 2.7 2.6 1.0 0.4 1.9 2.3 5.8 0.5 0.0 0.1 0.2 3.4 0.8 0.5 2.7 0.0 0.1 4.3 2.7 2.0 0.3 3.0 3.9 1.2 4.7 0.3 16.1 0.4 2.1 30.6 11.4 0.5 1.7 0.2 0.6 2.5 0.8 0.3 0.0 1.4 0.3 3.0 0.6 0.3 0.8 0.4 0.3 2.8 2.3 0.6 0.3 0.5 6.2 7.0 1.3 7.9 0.2 4.8 0.5 0.7 2.3 0.2 0.3 1.3 0.1 0.3 1.4 1.4 0.6 0.8 0.5 0.3 0.2 0.3 0.1 0.4 0.1 0.2 0.1 0.5 0.2 0.2 2.5 0.3 0.2 5.4 0.3 0.1 15.7 17.0 12.1 23.5 14.4 13.3 14.1 14.6 13.1 12.3 14.4 12.3 0.4 0.0 2.6 119.8 0.3 2.0 0.7 5.1 0.6 1.2 1.8 1.4 1.9 7.2 4.8 5.5 8.4 0.5 5.7 0.4 0.0 4.0 0.3 11.8 37.9 3.4 0.0 0.0 0.3 0.0 1.1 8.3 0.5 16.1 0.0 0.2 3.3 0.1 1.2 0.0 0.9 0.4 2.0 0.3 1.6 1.7 34.5 1.8 1.8 10.3 1.6 15.7 0.0 3.0 0.3 0.4 0.0 44.0 0.2 1.4 0.2 10.2 3.7 3.0 6.6 1.4 1.8 0.6 0.1 0.8 3.0 0.4 0.7 0.1 1.0 0.4 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PARD6B PAR-6B ENSG00000124171 "Par-6 family cell polarity regulator beta" Q9BYG5 20 50731580-50756795 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Glandular and luminal cells: 179.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 29.0;MCF7: 51.7;T-47d: 48.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013376 Uncertain Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Cytosol "HPA013376: AB_1854972" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-3)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.02e-5)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (9.33e-2)" "prognostic unfavorable (8.38e-4)" "unprognostic (2.27e-1)" "prognostic favorable (6.38e-5)" "unprognostic (1.84e-2)" "unprognostic (1.97e-1)" "unprognostic (4.18e-2)" "unprognostic (1.07e-2)" 1.9 1.1 1.6 0.8 2.0 2.3 3.5 3.7 1.8 1.7 8.4 2.5 3.6 1.4 8.2 3.1 3.8 2.5 0.8 2.7 1.8 16.1 4.4 5.4 1.0 1.8 2.1 1.1 4.6 4.3 1.4 3.9 1.6 1.2 2.3 8.9 1.8 1.7 3.9 2.9 3.2 0.8 1.8 1.1 5.7 2.7 2.0 0.9 3.7 0.9 2.1 1.7 1.5 2.4 5.4 6.2 1.7 3.7 1.1 0.4 8.0 0.4 0.6 0.9 0.7 29.0 12.7 2.4 5.4 0.1 3.8 4.3 2.6 3.9 1.5 1.2 1.5 1.3 2.1 11.5 1.2 0.9 1.3 0.1 1.9 0.5 1.6 1.7 0.1 2.3 3.1 1.6 0.1 51.7 2.5 2.3 3.0 9.0 2.3 1.4 1.7 2.3 12.9 5.9 1.1 1.6 4.1 9.6 3.0 7.2 48.8 1.3 0.2 0.5 3.2 0.5 1.0 1.9 1.3 2.0 1.3 0.9 1.1 1.6 0.2 1.5 1.4 0.3 1.5 1.1 1.4 1.4 0.3 1.3 2.2 1.4 1.1 1.6 0.6 1.3 0.9 0.4 1.6 2.0 3.7 1.8 2.7 1.8 1.8 2.1 1.6 1.8 2.0 2.4 0.4 189.1 50.4 2.9 4.5 63.0 58.9 17.0 30.7 14.4 60.3 15.0 4.3 37.1 31.1 90.1 54.2 35.5 4.0 68.6 41.1 26.2 4.0 110.1 14.4 1.7 14.9 0.4 11.5 24.4 15.0 4.7 55.5 179.2 1.3 1.8 1.8 20.1 3.7 5.0 10.6 26.7 22.4 0.8 4.2 2.5 1.8 3.5 16.0 1.9 1.2 12.3 2.1 1.5 4.6 57.5 39.7 0.7 6.3 43.6 29.3 102.0 30.0 62.7 6.6 1.2 4.8 16.6 9.4 34.7 68.3 48.4 6.3 1.5 27.3 102.7 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PATL2 Pat1a ENSG00000229474 "PAT1 homolog 2" C9JE40 15 44665732-44711316 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.7;lymphoid tissue: 17.2" "Cell type enhanced" "Detected in many" "B-cells: 29.2;dendritic cells: 19.1;NK-cells: 51.5;Plasma cells: 15.7;T-cells: 29.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 21.6;memory CD4 T-cell: 6.0;memory CD8 T-cell: 17.7;naive CD8 T-cell: 12.8" "Lineage enriched" "Detected in many" 6 "T-cells: 21.6" "Cell line enriched" "Detected in some" 28 "U-266/70: 124.9" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (3.30e-3)" "unprognostic (5.55e-2)" "unprognostic (7.28e-2)" "unprognostic (1.11e-2)" "unprognostic (3.00e-3)" "unprognostic (7.82e-2)" "unprognostic (3.69e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-2)" "unprognostic (9.48e-2)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (9.69e-4)" 0.9 1.1 0.8 7.7 1.1 7.7 1.3 0.6 0.8 0.3 1.5 2.1 2.4 1.1 1.7 0.6 1.4 2.3 0.7 0.7 0.8 0.5 1.7 3.9 17.2 1.8 1.1 0.9 0.6 0.4 0.2 1.0 1.1 0.8 2.5 0.1 2.5 0.6 0.3 2.7 3.2 0.8 0.9 13.9 3.2 0.5 1.2 3.6 0.7 0.0 10.8 2.1 0.2 1.4 0.2 0.0 0.0 0.1 0.0 1.1 2.8 0.1 0.4 0.9 0.9 0.6 1.2 0.9 0.1 0.3 1.8 1.3 0.1 0.2 0.5 2.1 0.0 1.2 0.0 0.1 0.5 0.5 0.7 1.2 0.1 0.5 0.3 0.2 0.0 1.4 0.2 4.5 0.3 0.3 0.1 1.4 0.4 0.1 0.1 1.8 0.0 0.5 0.1 0.4 0.1 0.0 0.0 1.3 0.1 0.2 0.1 0.9 0.6 0.3 0.0 0.8 0.0 124.9 4.3 0.4 1.2 3.1 0.4 1.5 0.3 2.6 21.6 0.7 3.2 3.3 6.0 17.7 0.7 3.5 3.6 12.8 1.6 2.7 0.5 0.6 0.9 3.7 0.8 1.1 0.6 0.8 0.7 0.8 1.8 1.1 1.1 0.9 1.2 1.4 1.4 3.2 1.7 1.6 29.2 0.9 0.6 0.5 0.6 0.0 0.6 0.6 11.7 0.0 0.4 0.0 0.0 0.2 19.1 2.0 0.0 0.4 0.3 2.4 1.0 1.8 0.0 3.0 0.3 0.6 0.5 1.9 8.2 0.8 0.0 1.2 1.4 1.0 2.0 0.0 0.4 1.4 0.0 4.8 2.3 0.0 0.3 5.6 0.0 3.7 5.2 0.0 51.5 0.5 1.3 0.4 0.3 0.0 15.7 0.6 2.2 0.4 8.5 0.0 0.0 1.0 2.6 0.1 0.4 1.4 0.9 0.3 29.8 1.8 0.9 1.3 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 72.3;Fibroblasts: 56.3;Leydig cells: 37.9;Peritubular cells: 58.6;Sertoli cells: 19.7;Smooth muscle cells: 25.5;Theca cells: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 148.2;ASC diff: 175.0;ASC TERT1: 190.8;BJ hTERT+: 86.8;fHDF/TERT166: 143.3;HHSteC: 129.4;HSkMC: 195.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" 22.2 5.2 2.6 7.9 3.0 0.1 13.5 2.8 3.2 25.3 2.6 12.2 9.3 30.4 11.2 6.4 11.7 22.5 6.5 2.5 4.8 7.1 2.1 7.2 1.7 4.1 5.8 21.0 1.5 2.0 2.4 44.2 3.8 17.5 13.8 2.1 6.5 13.5 2.6 4.1 8.7 18.4 3.2 6.4 6.7 4.5 3.9 3.6 5.1 23.2 1.4 10.8 8.4 3.0 0.0 0.3 148.2 0.0 175.0 190.8 0.1 27.4 86.8 5.0 7.7 0.3 0.0 0.0 0.1 143.3 0.4 0.4 34.2 0.7 2.6 0.2 1.0 0.0 0.0 0.0 129.4 0.0 0.1 195.9 0.3 9.4 3.8 4.7 1.0 0.7 0.0 0.6 2.8 0.0 3.9 0.1 0.3 0.0 2.7 11.7 4.1 0.0 0.0 0.1 0.0 9.6 0.0 0.0 0.2 38.3 0.9 0.0 0.0 69.3 4.2 13.9 0.5 0.2 0.0 0.0 3.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 2.8 3.2 2.5 4.8 4.1 5.8 3.8 3.2 3.9 3.0 3.4 0.0 0.5 1.3 0.0 4.1 0.4 0.1 2.2 2.5 1.1 1.7 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 1.9 72.3 3.0 0.0 0.0 0.2 0.0 0.3 56.3 0.0 1.7 0.0 6.4 2.5 0.0 3.1 0.0 9.0 0.0 0.0 0.0 7.8 1.3 37.9 0.9 1.8 10.3 0.0 6.8 0.0 0.0 0.6 0.0 0.0 58.6 0.1 0.0 0.0 0.1 0.0 0.2 19.7 6.6 25.5 0.6 0.1 1.2 2.6 0.8 0.7 18.5 0.0 0.1 PCDH7 "BH-Pcdh, PPP1R120" ENSG00000169851 "Protocadherin 7" O60245 4 30720415-31146805 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Group enriched" "Detected in many" 8 "Astrocytes: 311.8;Excitatory neurons: 1152.0;Inhibitory neurons: 882.3;Oligodendrocyte precursor cells: 917.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 43.4;RH-30: 120.4;RT4: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011866, HPA046521" Uncertain Enhanced "Plasma membrane,Cell Junctions" NA NA 340000 "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA011866: AB_1855047, HPA046521: AB_2679682" "unprognostic (1.87e-1)" "unprognostic (8.88e-2)" "unprognostic (4.48e-2)" "unprognostic (3.32e-1)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.96e-1)" "unprognostic (8.39e-2)" "unprognostic (1.02e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-4)" "prognostic unfavorable (6.42e-4)" "unprognostic (1.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.56e-2)" 1.8 3.2 10.5 5.2 14.6 0.0 3.0 0.0 33.7 23.9 0.0 19.2 3.2 16.9 25.1 14.3 9.7 8.1 19.1 23.7 50.1 2.0 1.0 2.9 1.4 13.0 14.3 4.7 0.9 1.1 0.2 0.2 14.3 10.6 7.8 3.4 0.8 18.2 0.6 11.6 5.0 22.1 3.9 18.6 11.4 1.0 46.3 1.4 4.1 0.4 1.2 16.3 5.9 11.8 0.0 1.1 14.4 20.1 29.5 28.5 0.0 3.8 0.0 1.9 0.9 1.9 26.5 0.0 0.1 0.2 0.0 15.3 1.3 38.5 3.4 0.0 43.4 0.1 26.8 0.0 30.4 0.6 0.0 17.2 8.8 1.0 10.7 17.5 7.5 0.0 0.0 0.0 9.0 0.1 0.0 0.1 8.8 9.3 4.0 0.0 120.4 0.0 0.9 65.2 0.9 0.2 0.4 1.2 1.3 8.2 1.8 6.9 0.0 24.1 6.2 6.7 0.0 0.0 0.0 0.0 18.8 0.1 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 14.6 0.0 33.7 23.7 50.1 13.0 14.3 14.3 3.9 46.3 11.8 1.1 0.0 0.0 311.8 0.3 85.0 92.4 25.7 46.7 46.8 0.7 9.0 83.2 0.0 13.7 64.4 0.0 0.1 0.0 0.3 0.0 0.6 16.9 66.8 8.4 7.6 0.0 0.0 1152.0 0.7 0.1 24.0 20.9 60.4 1.3 0.8 19.2 0.1 0.3 10.1 882.3 0.5 4.1 1.0 3.5 10.4 0.3 1.3 21.4 43.1 0.0 1.3 0.0 917.3 26.4 26.5 0.0 28.6 1.3 26.1 0.0 0.2 27.0 3.4 0.0 51.3 11.0 1.1 2.7 18.5 38.6 0.1 1.8 1.7 0.3 50.3 PCDH9 ENSG00000184226 "Protocadherin 9" Q9HC56 13 66302834-67230445 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 159.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4339.5;Excitatory neurons: 5259.8;Inhibitory neurons: 2489.4;Oligodendrocyte precursor cells: 6313.8;Oligodendrocytes: 14117.8" "Cancer enriched" "Detected in single" 8 "glioma: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 4.5;memory B-cell: 5.3;naive B-cell: 17.3" "Group enriched" "Detected in many" 9 "B-cells: 17.3;granulocytes: 4.5" "Cell line enhanced" "Detected in many" "AF22: 25.1;LHCN-M2: 41.6;TIME: 48.9;U-698: 64.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015581 Approved Nucleoplasm,Centrosome NA NA 2900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Centrosome" "HPA015581: AB_1855048" "unprognostic (1.77e-1)" "unprognostic (8.36e-2)" "unprognostic (9.12e-3)" "unprognostic (4.42e-5)" "unprognostic (7.54e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-1)" "unprognostic (1.38e-1)" "unprognostic (2.35e-1)" "unprognostic (8.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.14e-1)" "unprognostic (8.47e-4)" "unprognostic (6.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (4.35e-4)" 3.8 2.2 37.1 0.4 84.0 3.3 1.0 41.5 53.2 0.9 0.0 1.2 0.2 0.2 1.2 0.3 0.4 1.5 4.9 37.8 51.3 2.5 1.5 1.5 0.7 49.9 52.1 0.6 1.3 0.0 2.0 0.0 56.8 1.6 0.5 9.4 0.3 4.2 1.3 0.2 0.5 0.5 27.1 0.9 1.9 0.9 76.1 2.2 1.0 1.1 0.6 0.7 1.0 159.3 0.0 19.3 25.1 0.0 6.6 5.1 0.0 3.8 0.2 2.7 1.0 0.1 0.1 5.7 0.1 2.9 0.9 0.0 2.1 0.6 1.2 0.0 10.1 0.3 0.2 0.0 6.3 0.7 0.3 12.1 0.7 3.1 5.0 0.6 2.1 2.2 0.6 0.3 41.6 1.6 12.2 0.0 0.2 0.5 2.5 18.2 0.8 0.0 0.5 0.0 3.2 1.3 0.0 0.1 0.3 0.6 0.0 0.1 48.9 1.4 1.2 5.9 2.0 7.3 0.0 64.2 10.6 0.0 5.0 4.5 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 17.3 0.1 0.1 0.1 0.9 0.0 1.2 0.0 0.2 37.1 84.0 41.5 53.2 37.8 51.3 49.9 52.1 56.8 27.1 76.1 159.3 5.6 19.2 68.0 4339.5 29.1 1.9 2.5 0.0 1.8 318.8 9.2 14.7 152.5 0.0 4.4 5.5 20.9 0.2 4.3 0.9 9.8 1.9 3.6 0.3 6.4 4.7 62.4 2.5 5259.8 0.0 0.2 76.3 11.7 0.3 1.3 1.0 19.2 8.6 0.3 198.5 2489.4 1.4 0.0 1.9 1.4 3.0 29.5 3.7 10.6 237.0 0.3 87.8 2.1 6313.8 14117.8 0.3 1.2 14.7 1.4 2.0 0.0 0.8 0.0 27.1 6.6 27.9 25.4 6.8 5.4 1.2 0.3 0.0 2.7 3.7 0.8 0.8 PCDHA11 "CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11" ENSG00000249158 "Protocadherin alpha 11" Q9Y5I1 5 140868183-141012347 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;parathyroid gland: 2.7;retina: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;AN3-CA: 10.7;EFO-21: 7.6;MCF7: 4.4;T-47d: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077160 Approved "Vesicles,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cell Junctions" "Cytoplasmic bodies" "HPA077160: AB_2686827" "unprognostic (1.54e-2)" "unprognostic (1.83e-3)" "unprognostic (2.75e-1)" "unprognostic (2.59e-1)" "unprognostic (6.98e-3)" "unprognostic (1.36e-1)" "unprognostic (9.28e-3)" "unprognostic (2.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (3.13e-4)" "unprognostic (9.91e-5)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (3.26e-2)" 0.2 0.3 1.5 0.1 1.3 0.0 0.2 4.2 2.2 0.8 0.0 0.1 0.0 0.5 0.1 0.0 0.2 0.8 0.0 1.1 0.3 0.7 0.1 0.4 0.1 0.0 1.5 0.0 1.8 2.7 1.0 0.0 0.3 0.1 0.0 2.4 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.7 0.0 2.1 4.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.6 0.0 0.8 0.0 0.1 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.3 0.0 1.0 0.0 0.1 0.0 4.4 0.0 0.0 3.5 0.8 2.8 0.0 0.0 0.0 0.4 1.6 0.2 1.9 0.0 1.9 0.4 1.9 6.5 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 4.2 2.2 1.1 0.3 0.0 1.5 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHB11 "ME2, PCDH-BETA11" ENSG00000197479 "Protocadherin beta 11" Q9Y5F2 5 141199610-141203779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 4.9;Endometrial stromal cells: 3.5;Fibroblasts: 4.8;Peritubular cells: 3.4;Sertoli cells: 6.6;Skeletal myocytes: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.6;EFO-21: 8.9;U-2 OS: 3.0" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-2)" "unprognostic (1.42e-1)" "unprognostic (6.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.07e-1)" "unprognostic (2.89e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" "unprognostic (1.37e-2)" "unprognostic (9.79e-2)" "unprognostic (6.47e-3)" 1.3 0.6 0.2 0.5 0.5 0.2 0.9 0.9 1.2 1.2 0.0 1.0 0.2 1.5 0.5 0.7 0.9 0.9 0.8 0.5 0.0 0.7 0.2 0.8 0.1 0.3 0.3 1.6 2.6 2.6 0.7 0.6 0.1 0.9 0.3 0.6 0.8 1.0 0.4 0.8 0.4 1.2 0.4 0.6 0.6 0.4 0.0 0.3 0.6 0.6 0.1 0.9 0.6 0.4 0.0 0.1 1.8 5.6 0.1 0.1 1.1 0.1 0.5 0.0 0.0 0.0 0.1 0.0 8.9 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.8 0.0 0.1 0.0 1.4 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.0 2.2 0.0 0.0 0.2 2.2 0.3 1.3 0.1 0.7 0.3 1.3 0.0 0.3 0.1 3.0 2.4 0.0 0.1 0.0 0.0 1.4 0.1 1.5 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.5 0.9 1.2 0.5 0.0 0.3 0.3 0.1 0.4 0.0 0.4 1.9 3.2 0.5 0.0 0.0 0.0 0.7 0.0 0.0 4.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.7 3.5 1.9 2.4 0.0 0.0 1.8 0.0 4.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.1 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 1.0 0.0 3.4 0.1 0.9 0.0 0.9 0.0 0.2 6.6 4.1 1.7 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.7 PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.0;Endometrial stromal cells: 2.8;Fibroblasts: 2.8;Melanocytes: 3.6;Peritubular cells: 2.6;Skeletal myocytes: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;ASC diff: 2.5;EFO-21: 3.0;RH-30: 3.2;U-2 OS: 2.3;U-2197: 2.4" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" 1.3 0.6 0.1 0.4 0.7 0.0 1.2 0.9 1.1 1.9 0.0 1.3 0.2 2.7 0.8 0.4 1.9 1.0 1.4 0.8 0.1 0.6 0.3 1.4 0.1 0.3 0.3 2.2 1.3 1.0 2.0 0.4 0.0 0.9 0.4 0.8 0.6 0.9 0.7 0.5 0.6 1.8 0.1 0.7 0.6 1.1 0.1 0.1 0.6 0.9 0.1 1.2 1.1 0.7 0.0 0.0 0.7 2.7 2.5 1.4 0.4 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.0 0.3 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.5 0.5 3.2 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.6 0.2 2.1 0.4 0.2 0.4 2.3 2.4 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.9 1.1 0.8 0.1 0.3 0.3 0.0 0.1 0.1 0.7 1.9 0.0 1.1 0.0 0.0 0.4 0.0 0.2 0.0 4.0 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.8 0.1 2.8 1.3 1.8 0.0 0.0 0.9 0.0 2.8 0.5 0.1 0.0 0.1 1.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 3.6 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.1 0.0 0.2 0.0 0.3 0.0 2.2 1.6 1.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Bipolar cells: 8.4;Endometrial stromal cells: 5.5;Fibroblasts: 10.2;Horizontal cells: 11.8;Skeletal myocytes: 6.6" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Cell line enhanced" "Detected in many" "ASC diff: 200.7;HSkMC: 186.2;U-138 MG: 244.1;WM-115: 382.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" 63.3 64.3 248.0 15.4 241.0 0.2 59.9 221.6 308.1 107.8 165.1 60.4 7.4 81.3 60.8 54.5 62.6 30.2 77.8 232.3 227.5 36.6 29.5 101.9 9.5 236.9 241.0 65.1 34.7 36.8 79.0 37.1 216.6 66.0 20.4 36.3 46.4 40.7 27.6 64.7 32.0 39.5 216.5 22.2 38.7 22.0 263.5 15.7 45.7 26.3 14.8 60.6 80.0 220.8 12.8 7.7 48.1 14.0 200.7 178.3 0.6 58.6 162.6 30.9 32.5 0.0 12.7 43.5 39.7 108.0 111.7 46.2 6.1 20.7 28.2 0.2 20.0 0.1 1.2 1.2 62.6 0.5 1.5 186.2 31.6 46.9 37.2 104.2 19.7 0.0 0.2 1.6 79.2 24.8 1.0 5.4 2.3 0.8 0.1 30.0 97.1 0.4 17.9 13.7 16.6 69.8 17.3 0.6 115.9 16.8 40.0 66.9 22.1 244.1 12.2 46.7 72.2 0.1 0.6 0.7 60.3 0.1 382.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.1 248.0 241.0 221.6 308.1 232.3 227.5 236.9 241.0 216.6 216.5 263.5 220.8 2.5 0.0 0.0 0.0 0.3 0.3 0.5 0.3 8.0 8.4 0.2 1.1 0.8 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.2 1.4 0.3 5.5 1.9 0.0 0.0 0.0 0.2 0.2 10.2 0.0 0.5 0.0 0.2 1.1 0.0 0.3 11.8 0.0 0.2 0.0 0.3 0.3 0.7 1.2 0.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.6 0.0 0.1 0.0 1.0 0.0 6.6 1.7 1.6 0.0 3.9 0.1 0.7 0.1 3.5 0.0 0.5 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568121 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 432.1;liver: 681.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 703.8;Distal tubular cells: 588.9;Hepatocytes: 1184.0;Proximal enterocytes: 2209.9;Proximal tubular cells: 3547.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "ASC diff: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 840000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 59.2 1.1 0.8 1.7 0.8 0.0 29.8 0.7 1.6 0.0 0.6 57.8 110.4 1.2 0.2 0.4 0.9 5.0 1.0 0.7 1.4 432.1 681.4 0.2 0.3 0.7 0.9 1.6 0.4 0.0 21.1 0.3 0.8 0.2 79.8 0.5 1.1 0.2 0.4 0.9 143.9 2.9 0.6 0.3 0.9 0.0 1.3 0.1 0.8 6.5 0.0 0.8 0.1 0.8 0.0 0.0 0.0 0.0 20.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.6 0.7 1.4 0.7 0.9 0.8 0.6 1.3 0.8 0.7 0.0 0.0 0.0 21.3 0.1 0.0 0.0 15.9 0.3 0.7 0.6 1.0 61.5 0.6 90.1 0.0 0.1 0.1 703.8 588.9 0.6 0.1 1.3 1.5 2.7 53.9 40.2 0.0 0.0 0.0 2.3 19.9 8.5 8.9 0.1 29.6 1184.0 0.0 3.3 0.0 293.6 0.0 22.6 0.0 0.0 0.0 12.8 0.0 1.9 0.0 9.9 0.0 0.0 0.0 0.1 285.5 0.0 0.0 0.0 2209.9 3547.9 0.0 0.4 0.0 0.3 6.0 0.0 0.1 10.3 0.3 0.3 10.2 1.5 348.5 0.1 PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 196.1;kidney: 99.1;liver: 374.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 309.3;Proximal enterocytes: 752.6;Proximal tubular cells: 237.1" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 104.7;hTCEpi: 104.7;SK-MEL-30: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria NA NA 3500000 "Cluster 51: Monocytes - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favorable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" 25.5 10.7 3.2 8.0 3.9 4.5 21.1 3.8 3.3 6.8 3.4 44.8 196.1 5.8 3.1 20.0 5.9 4.5 5.8 3.1 3.9 99.1 374.1 16.5 8.7 4.6 4.2 3.0 34.8 17.4 8.0 2.8 4.1 9.1 19.2 2.7 18.6 7.1 2.6 12.6 136.3 3.8 4.0 21.7 16.0 19.7 3.9 3.7 18.9 1.2 7.5 10.8 10.0 4.3 17.6 9.8 2.7 18.1 11.0 10.5 46.0 21.5 25.6 17.4 28.4 16.1 19.9 44.6 2.6 33.4 5.6 25.4 18.0 28.1 13.8 22.8 0.8 8.0 5.0 84.2 104.7 15.8 33.4 12.9 104.7 10.6 26.5 5.0 14.0 50.6 23.4 79.3 6.4 74.6 4.0 7.6 3.1 39.4 13.0 8.7 10.5 26.0 5.3 26.7 11.3 18.2 16.5 21.2 103.9 2.6 28.5 24.1 2.7 3.8 19.7 5.6 6.0 53.2 18.6 11.0 10.6 24.5 9.6 0.3 11.6 3.5 4.0 21.6 4.1 11.4 4.5 4.5 15.3 7.3 2.7 2.5 1.3 2.2 22.0 2.5 9.1 6.1 3.2 3.9 3.8 3.3 3.1 3.9 4.6 4.2 4.1 4.0 3.9 4.3 4.8 12.8 28.5 1.3 17.9 3.3 10.2 12.3 5.7 4.7 8.6 5.2 1.8 18.6 8.0 18.4 0.0 4.7 4.3 91.2 35.2 18.9 60.1 1.6 5.2 5.6 9.1 24.4 0.5 76.3 14.3 7.4 16.8 4.5 1.3 1.6 13.2 309.3 63.8 0.0 0.9 60.8 18.3 25.8 5.7 30.8 3.4 16.4 7.2 1.0 22.9 5.8 7.2 0.0 0.1 29.0 87.8 3.0 13.3 7.6 752.6 237.1 4.8 5.5 0.0 3.4 18.7 19.8 1.0 9.1 4.8 3.0 7.6 6.8 72.0 15.0 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.4;retina: 33.3;testis: 112.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4139.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 53.4;white matter: 16.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 8.4;Karpas-707: 4.2;NB-4: 17.7" "Region enriched" "Detected in many" 44 "cerebellum: 2160.4" "Region enriched" "Detected in all" 28 "cerebellum: 552.9" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" Vesicles "HPA057428: AB_2683436" "prognostic favorable (7.93e-4)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-4)" "unprognostic (1.19e-1)" "unprognostic (4.88e-5)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (9.15e-3)" "unprognostic (6.01e-2)" "unprognostic (1.36e-2)" "unprognostic (8.17e-2)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "prognostic favorable (2.76e-5)" 0.4 1.6 0.4 1.1 0.6 3.7 5.5 53.4 2.3 2.1 0.0 0.6 1.4 0.9 3.3 2.0 2.4 2.3 2.2 0.5 0.0 8.0 3.7 2.2 3.0 0.1 3.5 0.1 5.4 1.1 1.4 0.4 5.5 5.9 0.3 33.3 16.3 1.9 0.2 7.0 1.6 0.0 0.1 3.0 3.1 112.4 0.0 3.1 5.7 0.0 1.4 0.9 1.6 16.8 1.8 0.4 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 1.6 0.7 1.1 0.0 0.0 1.3 0.0 0.2 0.0 0.8 0.6 2.6 2.8 0.1 0.0 0.3 8.4 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 4.2 0.0 0.3 0.3 17.7 0.4 0.3 0.0 0.8 0.2 0.7 0.8 0.1 0.1 0.0 1.4 1.4 0.0 0.4 3.7 3.4 0.2 0.0 0.5 0.4 0.0 1.4 0.7 0.2 0.0 2.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.1 0.2 0.3 0.2 0.3 0.8 0.2 0.0 0.6 0.0 1.7 0.4 0.6 53.4 2.3 0.5 0.0 0.1 3.5 5.5 0.1 0.0 16.8 0.1 0.0 2.3 0.0 0.2 0.8 1.1 1.4 0.0 734.7 7.7 5.8 0.0 2.8 1.8 5.5 22.9 0.2 2.7 0.7 9.8 0.8 836.5 1.0 0.1 2.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 1.5 1.3 1.3 0.0 0.5 0.4 23.5 0.0 0.4 0.0 0.8 1.3 4139.3 10.5 7.1 1.8 1.0 1.5 40.7 2.1 0.0 0.0 0.4 0.1 13.2 0.3 1.0 1.3 0.5 0.4 100.3 19.7 0.0 0.1 14.5 9.0 0.0 1.1 0.0 1.0 0.0 0.6 0.6 PCSK4 "DKFZp434B217, MGC34749, PC4, SPC5" ENSG00000115257 "Proprotein convertase subtilisin/kexin type 4" Q6UW60 19 1481428-1490752 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 66.0" "Group enriched" "Detected in many" 4 "Early spermatids: 277.1;Late spermatids: 679.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.7;HMC-1: 3.7;JURKAT: 5.3;U-266/70: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA005572 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA005572: AB_1855087" "unprognostic (1.00e-2)" "unprognostic (9.12e-2)" "unprognostic (2.36e-3)" "prognostic favorable (9.45e-5)" "unprognostic (5.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.78e-1)" "unprognostic (6.34e-3)" "unprognostic (2.94e-1)" "unprognostic (8.29e-3)" "unprognostic (1.93e-2)" "unprognostic (7.44e-2)" "unprognostic (6.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.71e-2)" "unprognostic (3.57e-2)" "unprognostic (7.03e-2)" 0.8 1.4 1.1 0.3 1.1 0.6 1.2 0.9 2.5 1.7 1.3 1.3 1.7 1.1 0.1 1.1 3.2 0.6 0.5 1.4 1.6 3.7 4.0 1.1 0.3 1.9 2.8 1.1 2.8 0.9 7.1 0.2 1.5 1.8 0.1 0.6 1.1 1.2 0.3 0.6 1.1 0.1 1.8 0.7 1.4 66.0 1.6 0.4 3.4 0.0 0.1 1.0 1.2 0.9 0.6 0.3 1.2 6.7 0.1 0.2 1.8 0.5 0.1 0.0 0.2 0.6 1.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.1 0.3 1.1 1.0 0.4 0.0 3.7 0.6 0.0 0.0 0.1 0.3 0.2 5.3 1.2 1.8 0.0 0.0 0.1 0.3 0.1 0.3 0.4 1.2 0.1 0.1 0.4 0.0 0.0 1.4 0.1 0.3 0.1 0.4 2.5 0.4 0.0 0.5 0.0 0.1 0.0 7.7 1.5 0.3 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 1.1 0.9 2.5 1.4 1.6 1.9 2.8 1.5 1.8 1.6 0.9 0.2 0.0 1.1 12.1 0.1 0.6 0.9 1.8 0.6 1.5 3.1 2.2 2.3 1.5 3.6 0.0 8.4 0.5 1.7 1.6 5.9 1.8 277.1 5.2 1.0 0.5 0.0 1.7 3.2 1.0 0.5 0.8 3.1 1.1 0.0 3.3 0.0 3.2 0.8 3.3 3.7 1.4 0.0 0.3 0.0 679.2 6.2 1.1 3.6 3.7 0.0 2.4 0.0 1.0 1.6 0.9 1.1 5.3 1.4 0.5 2.8 1.9 8.3 9.1 0.0 0.2 0.5 98.0 9.6 1.2 0.0 0.3 0.7 2.4 2.1 0.7 PCYT1B "CCT-beta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1, choline, beta" Q9Y5K3 X 24558087-24672677 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.2;retina: 12.1;testis: 13.4" "Cell type enhanced" "Detected in some" "Astrocytes: 23.5;Early spermatids: 29.1;Late spermatids: 90.1;Muller glia cells: 30.1;Oligodendrocyte precursor cells: 23.6;Oligodendrocytes: 41.9" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 10.3;CACO-2: 22.2;HEL: 25.7;Hep G2: 10.2;NTERA-2: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" "HPA006367: AB_1079585" "unprognostic (4.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (9.88e-2)" "unprognostic (6.83e-2)" "unprognostic (5.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (5.64e-2)" "unprognostic (2.63e-6)" "unprognostic (2.62e-4)" "unprognostic (4.56e-2)" "unprognostic (1.75e-2)" "unprognostic (1.96e-4)" 0.1 0.8 12.1 0.2 12.2 0.8 0.1 10.6 12.8 0.7 7.5 1.2 0.3 1.6 0.6 0.8 2.2 0.4 2.9 13.2 9.8 0.2 0.0 0.7 0.0 9.5 10.2 1.4 1.5 0.0 1.3 1.3 9.8 0.8 0.2 12.1 0.1 2.4 0.0 0.1 0.6 2.5 8.6 0.2 0.2 13.4 11.4 0.5 0.0 0.0 0.0 0.3 0.3 12.9 0.0 0.0 10.3 0.1 0.0 0.0 0.1 0.0 0.9 0.3 0.1 22.2 0.0 0.0 5.2 0.0 0.0 1.0 4.2 0.0 0.0 0.0 0.1 25.7 0.0 10.2 0.1 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 3.9 0.5 11.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 7.2 5.8 0.0 0.0 0.5 7.1 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 4.4 0.7 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 12.1 12.2 10.6 12.8 13.2 9.8 9.5 10.2 9.8 8.6 11.4 12.9 0.0 0.0 0.0 23.5 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.5 1.6 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.8 29.1 10.7 0.2 0.1 1.8 1.3 5.6 0.0 0.0 0.4 0.0 0.2 4.5 5.8 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 90.1 0.3 0.9 0.0 3.7 0.3 30.1 0.0 23.6 41.9 0.2 0.0 2.6 0.1 0.1 0.0 0.5 6.4 1.6 0.0 0.0 1.0 1.8 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.1 PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900958-81911432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.7;testis: 261.7" "Group enriched" "Detected in many" 7 "Early spermatids: 763.2;Late spermatids: 2829.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 218.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Approved Nucleoplasm,Cytosol NA NA 84000 "Cluster 26: Non-specific - Mitochondria" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA023033: AB_1855094, HPA023034: AB_1855095" "unprognostic (4.05e-3)" "unprognostic (4.39e-3)" "unprognostic (3.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (9.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-1)" "unprognostic (4.24e-1)" "unprognostic (8.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "prognostic favorable (4.29e-6)" "unprognostic (1.19e-1)" "unprognostic (8.59e-2)" "unprognostic (1.63e-1)" "unprognostic (4.47e-2)" 29.7 16.8 40.0 9.5 40.1 12.1 25.2 44.4 45.8 14.9 30.4 25.5 63.9 18.0 13.5 26.3 23.9 9.9 47.7 41.2 37.7 44.0 165.7 21.3 12.0 47.0 43.0 20.9 25.3 20.2 14.4 12.0 47.3 24.2 16.7 8.6 22.3 12.1 33.5 16.3 43.0 9.6 41.3 12.8 35.4 261.7 41.0 13.5 16.2 29.3 11.9 21.2 15.1 44.0 42.6 23.9 18.8 53.1 91.8 48.0 27.9 29.9 63.2 40.7 48.0 94.0 43.0 14.8 16.0 31.1 75.3 34.5 28.6 55.1 23.5 4.5 24.3 32.1 33.3 218.2 97.8 32.5 26.0 39.8 31.4 36.8 28.4 14.5 38.6 44.0 60.6 29.6 30.8 35.7 39.3 40.1 15.1 147.2 25.9 25.4 20.2 52.4 49.2 78.8 23.9 21.9 22.4 121.7 29.0 36.5 33.9 75.3 26.1 30.0 19.7 22.9 25.0 19.3 9.1 15.3 31.2 42.8 29.9 1.5 2.4 0.9 4.6 2.6 3.0 4.2 5.5 4.7 4.5 5.6 4.5 4.6 0.7 3.3 2.1 4.4 3.6 3.1 40.0 40.1 44.4 45.8 41.2 37.7 47.0 43.0 47.3 41.3 41.0 44.0 11.5 0.0 17.3 15.0 11.1 5.4 8.1 11.7 6.8 12.5 25.1 11.0 17.0 62.9 9.6 25.8 0.0 73.1 21.0 41.6 119.3 19.5 763.2 29.0 7.5 8.7 13.9 47.8 5.3 18.3 39.7 7.7 36.2 15.8 9.5 39.6 21.8 166.0 24.1 16.8 4.6 29.1 20.3 11.8 3.3 2829.0 27.7 8.1 33.8 0.0 14.7 26.7 22.6 3.5 12.2 17.8 18.8 25.9 13.4 11.4 144.4 130.3 29.4 10.6 26.3 6.2 11.5 253.1 18.1 16.5 5.7 50.8 13.6 34.4 48.7 7.7 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549601-54579239 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 76.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.6;Inhibitory neurons: 10.2;Kupffer cells: 13.0;Macrophages: 9.4;Sertoli cells: 13.1;Smooth muscle cells: 13.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 76.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 12.7;HMC-1: 14.9;NB-4: 10.7;THP-1: 9.0;U-937: 7.2" "Region enriched" "Detected in all" 6 "basal ganglia: 999.4" "Region enriched" "Detected in all" 7 "basal ganglia: 228.7" HPA018492 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA018492: AB_1855119" "unprognostic (2.90e-1)" "unprognostic (1.51e-1)" "unprognostic (7.67e-4)" "unprognostic (5.63e-3)" "unprognostic (7.02e-2)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.84e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.77e-6)" "unprognostic (6.64e-4)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" 9.1 1.1 8.4 4.0 76.9 4.8 4.6 0.0 13.7 2.0 0.0 7.4 1.0 2.7 1.8 1.7 2.0 2.2 1.4 6.3 0.1 0.8 1.0 2.3 1.3 0.0 0.0 8.6 0.4 6.1 0.3 0.2 0.0 1.3 1.0 0.4 1.0 1.4 0.6 1.4 3.4 4.0 0.0 4.0 3.3 0.7 2.4 0.9 2.0 1.0 0.8 8.7 1.5 4.9 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 2.1 0.0 0.0 12.7 0.6 4.3 0.0 0.0 0.0 5.5 14.9 0.7 0.0 0.0 0.0 0.0 0.0 5.5 0.0 2.3 0.0 0.0 0.5 10.7 3.5 0.0 0.0 2.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 2.5 0.0 7.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 76.9 0.0 13.7 6.3 0.1 0.0 0.0 0.0 0.0 2.4 4.9 2.3 0.0 1.1 1.6 1.8 1.0 0.2 0.0 0.6 2.7 0.2 0.6 3.6 0.0 0.6 3.7 0.0 0.1 1.4 0.0 0.0 0.0 6.3 0.1 0.0 0.8 1.8 3.6 18.6 0.0 0.0 1.5 0.0 0.0 0.0 4.4 0.0 0.3 8.5 5.0 10.2 0.0 0.0 13.0 2.5 4.9 2.1 9.4 0.0 2.8 6.7 0.1 4.1 1.0 0.9 0.0 0.0 3.0 2.6 0.4 0.0 0.0 0.0 0.2 13.1 0.6 13.7 0.8 0.6 0.2 0.4 0.3 2.8 0.4 0.1 0.1 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 68.9;heart muscle: 58.5" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1071.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.4;fHDF/TERT166: 148.3;hTERT-RPE1: 44.9;U-251 MG: 77.9;WM-115: 105.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.4 1.8 19.2 2.5 43.0 0.0 4.3 21.4 39.9 0.7 0.0 3.0 1.4 2.4 6.0 6.4 10.5 1.5 58.5 18.9 24.2 4.2 0.1 4.9 0.6 29.4 27.9 3.8 2.6 0.3 1.3 3.2 27.7 2.0 1.8 7.4 1.8 3.2 0.6 0.4 3.3 5.0 16.4 0.6 4.0 3.8 28.6 1.6 3.1 4.0 0.1 9.8 1.4 68.9 0.3 5.8 15.5 0.0 0.6 0.4 0.2 44.4 18.3 20.8 17.1 0.0 0.0 0.0 0.2 148.3 0.0 1.2 0.0 0.0 27.1 0.0 0.0 1.3 1.4 0.0 0.1 0.0 31.9 1.9 0.0 4.3 0.2 44.9 7.1 0.0 0.1 0.1 1.7 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 0.0 22.5 0.0 6.8 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.2 22.8 8.6 0.4 77.9 0.4 0.0 0.0 2.4 0.5 105.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 43.0 21.4 39.9 18.9 24.2 29.4 27.9 27.7 16.4 28.6 68.9 1.2 0.0 0.0 7.5 0.1 0.0 0.7 0.1 1.2 69.5 2.8 17.1 136.0 0.0 0.7 1.8 52.1 0.0 0.1 0.0 0.0 4.8 53.4 0.2 0.1 3.9 0.0 0.0 70.8 0.4 0.0 8.7 0.0 0.4 8.8 0.2 0.0 0.0 0.1 3.3 169.2 0.0 59.0 0.0 0.2 50.3 0.3 0.5 0.0 15.9 0.0 0.9 0.0 196.6 1071.4 0.2 0.0 0.4 0.1 0.2 0.0 0.0 2.2 4.7 0.0 0.9 9.4 1.3 1.2 0.2 0.0 0.0 0.1 1.2 0.0 0.0 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643804-14872044 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 64.5" "Cell type enhanced" "Detected in many" "Astrocytes: 171.7;Excitatory neurons: 140.5;Inhibitory neurons: 158.0;Microglial cells: 192.0;Oligodendrocyte precursor cells: 118.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 13.5" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.3" "Cell line enhanced" "Detected in many" "HL-60: 23.5;Karpas-707: 25.7;THP-1: 28.4;U-266/70: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "HPA056111: AB_2683041" "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favorable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" 64.5 1.1 1.3 12.4 2.1 10.1 12.2 13.5 2.6 3.4 0.0 25.2 2.9 0.7 0.5 2.9 0.5 3.7 4.7 1.9 2.6 3.0 25.8 10.2 14.9 2.8 1.7 0.5 8.3 0.2 4.4 7.6 1.9 8.7 10.7 0.5 14.0 1.6 0.4 0.5 6.0 1.7 2.3 8.9 2.6 9.6 2.0 7.3 0.8 2.4 7.9 8.5 1.9 2.6 0.0 2.5 5.6 9.2 10.9 0.1 2.2 0.6 0.1 0.0 0.0 8.5 0.0 0.0 0.1 0.0 2.6 0.0 8.5 0.0 0.0 0.2 18.7 0.3 13.1 17.5 3.9 23.5 0.1 0.8 0.0 0.0 0.5 0.0 0.1 6.6 20.6 25.7 0.0 0.3 4.7 11.4 7.6 3.1 4.1 11.0 2.5 17.7 0.0 1.9 8.5 15.8 2.3 14.6 5.1 2.5 0.0 28.4 0.0 0.0 1.3 0.0 0.0 28.8 9.4 0.7 0.2 4.0 1.7 0.0 0.5 2.5 1.0 0.6 2.1 0.2 3.1 2.4 0.3 0.1 6.3 5.7 3.8 0.1 1.0 0.1 3.5 1.5 1.3 2.1 13.5 2.6 1.9 2.6 2.8 1.7 1.9 2.3 2.0 2.6 1.5 16.0 8.9 171.7 6.4 0.3 0.9 0.0 0.6 1.0 0.3 0.3 11.1 0.0 6.2 1.8 0.0 1.4 26.7 11.5 1.9 0.0 19.0 0.3 5.1 4.0 1.2 12.8 140.5 5.0 2.8 9.7 7.7 0.3 36.1 0.5 4.2 64.1 7.6 0.0 158.0 13.7 0.0 13.1 3.7 13.4 1.5 15.6 0.0 192.0 10.8 6.3 8.2 118.6 5.4 1.8 22.3 9.1 28.9 3.3 0.7 2.0 3.6 0.5 0.0 3.4 3.0 48.8 19.5 0.1 0.1 2.5 60.9 0.0 9.4 1.1 PDE8B ENSG00000113231 "Phosphodiesterase 8B" O95263 5 77210449-77428256 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 124.7" "Cell type enhanced" "Detected in many" "Astrocytes: 64.9;Excitatory neurons: 183.1;Horizontal cells: 69.0;Inhibitory neurons: 276.5;Muller glia cells: 86.5;Oligodendrocyte precursor cells: 190.5" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 13.6;HeLa: 34.8;SK-BR-3: 11.1" "HPA036911, HPA036912" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA036911: AB_2675378, HPA036912: AB_10670377" "unprognostic (1.30e-1)" "unprognostic (7.95e-2)" "unprognostic (3.35e-2)" "unprognostic (7.61e-4)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-2)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.26e-2)" "unprognostic (3.98e-2)" "unprognostic (2.44e-1)" "unprognostic (9.04e-3)" "unprognostic (3.40e-2)" "unprognostic (3.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.19e-2)" 20.9 4.8 24.2 1.0 28.6 0.4 14.0 4.8 24.6 17.4 0.0 5.6 2.0 26.4 6.3 2.0 28.7 4.3 23.7 25.5 32.5 15.6 2.3 5.2 1.2 20.5 15.9 4.2 7.9 0.8 12.5 23.8 18.8 19.0 1.2 22.5 10.5 11.9 0.7 2.0 3.3 17.7 9.9 0.8 5.5 3.0 36.7 0.3 124.7 0.8 1.0 4.0 4.9 17.2 0.1 4.9 0.8 0.3 1.5 0.0 0.5 1.5 13.6 0.2 0.1 1.4 0.1 0.3 0.1 0.1 0.2 0.6 0.2 0.0 0.2 0.2 0.7 0.4 34.8 0.3 0.0 0.4 0.5 0.8 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.2 0.0 0.2 0.5 0.8 0.8 0.2 0.1 0.6 0.9 0.4 0.0 0.2 5.4 1.0 2.3 11.1 0.7 0.7 1.8 0.9 0.5 0.3 0.3 0.2 0.5 0.7 0.5 0.4 1.2 0.5 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 24.2 28.6 4.8 24.6 25.5 32.5 20.5 15.9 18.8 9.9 36.7 17.2 0.8 3.2 2.8 64.9 0.3 0.4 2.0 0.1 0.0 10.8 5.8 3.0 28.0 2.8 1.6 1.8 54.2 0.0 0.2 0.1 0.0 2.3 6.8 15.3 2.1 4.5 4.9 0.0 183.1 0.0 0.1 3.8 0.0 7.9 1.3 1.8 2.9 0.1 0.4 69.0 276.5 1.0 0.0 1.0 1.6 5.1 5.9 0.9 1.8 10.3 0.1 86.5 0.0 190.5 45.5 0.2 0.4 0.0 0.3 29.1 0.2 0.7 0.7 5.8 6.6 1.8 7.7 1.1 2.6 0.5 1.1 0.0 0.1 8.8 1.2 4.2 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 508.8;tongue: 770.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 479.9;Distal tubular cells: 354.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favorable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 93.0 69.0 62.1 37.9 66.9 88.1 63.1 66.2 91.5 55.9 84.4 112.6 87.0 53.1 78.9 76.8 49.1 29.3 508.8 68.2 67.0 174.1 118.3 47.2 36.6 64.5 62.7 50.6 83.4 161.0 48.7 43.1 65.0 48.4 104.4 90.1 109.7 63.4 459.0 60.9 82.1 51.8 59.6 49.3 121.8 24.0 67.4 52.3 64.5 770.2 59.1 61.7 56.1 71.1 124.9 151.4 107.9 114.2 102.3 77.7 131.6 83.8 74.6 170.2 130.7 216.6 78.2 212.2 60.6 102.0 226.7 159.0 334.2 145.8 178.1 70.1 186.1 104.8 264.0 194.2 107.8 170.3 82.8 100.9 132.8 157.3 154.4 85.6 105.3 129.8 94.2 87.2 120.7 164.5 142.7 173.5 110.0 227.4 261.7 145.2 180.9 260.3 298.0 125.1 59.7 62.6 134.1 167.8 158.1 229.8 177.1 118.1 65.4 87.6 78.6 240.9 108.6 73.3 82.0 140.5 82.4 117.2 77.4 99.9 87.4 65.3 72.3 119.9 88.9 103.4 69.4 79.5 115.7 82.1 67.7 72.0 15.5 98.1 109.1 76.9 84.4 89.6 62.1 66.9 66.2 91.5 68.2 67.0 64.5 62.7 65.0 59.6 67.4 71.1 34.1 44.8 44.4 18.6 30.7 29.8 59.7 135.4 25.0 59.0 37.0 29.3 479.9 87.2 74.8 152.6 33.3 105.0 32.5 73.0 354.1 88.8 2.5 41.2 33.7 36.8 41.9 55.8 21.2 59.8 120.7 49.2 49.5 36.9 42.6 39.7 18.2 76.3 73.2 25.2 24.6 64.4 71.2 26.8 30.5 4.1 35.4 32.5 56.9 9.4 40.8 49.0 26.8 13.0 11.5 47.4 52.5 40.6 43.3 47.1 88.6 213.7 33.1 69.1 32.9 37.5 51.7 51.1 25.3 45.2 33.4 133.4 31.6 25.4 130.3 55.8 PDHB PDHE1B ENSG00000168291 "Pyruvate dehydrogenase E1 subunit beta" P11177 3 58427630-58433857 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 299.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 300.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033794, HPA036744, HPA036745" Enhanced Supported Nucleoplasm,Mitochondria No No 61000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "CAB033794: AB_2162946, HPA036744: AB_10670921, HPA036745: AB_2675285" "unprognostic (2.06e-2)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (7.22e-2)" "unprognostic (1.42e-1)" "unprognostic (3.20e-2)" "unprognostic (6.13e-2)" "unprognostic (9.62e-2)" "unprognostic (5.94e-2)" "unprognostic (3.98e-1)" "unprognostic (2.35e-1)" "prognostic favorable (2.79e-8)" "unprognostic (2.67e-1)" "unprognostic (8.37e-2)" "unprognostic (1.06e-2)" "unprognostic (9.85e-2)" 59.9 76.5 48.7 42.2 50.2 25.7 42.9 53.9 62.7 43.3 63.6 56.8 42.5 38.5 44.6 57.4 37.7 35.9 175.0 49.7 52.3 100.8 110.7 36.4 53.1 51.7 49.4 26.5 36.4 88.8 44.1 57.0 51.5 48.5 60.4 30.7 45.9 52.1 272.6 36.8 37.6 63.8 51.6 42.8 53.9 42.3 53.1 53.1 40.8 299.4 56.0 49.7 35.9 54.3 66.5 90.9 92.3 69.8 91.7 111.1 110.4 81.6 101.3 117.9 120.6 165.1 62.6 140.3 44.9 103.8 109.0 37.6 113.2 74.9 90.0 81.7 83.0 125.4 163.7 126.0 92.5 103.0 67.9 97.9 67.7 95.5 55.8 137.5 103.1 114.2 65.9 61.5 129.5 63.1 98.2 107.8 127.2 69.2 101.3 46.3 71.8 136.1 188.1 89.1 63.7 70.2 75.6 107.2 85.4 131.3 159.0 108.7 76.3 62.9 83.7 66.8 94.2 85.2 129.9 99.2 96.2 120.8 60.7 57.8 98.9 98.7 83.2 115.1 87.9 102.2 81.7 80.5 141.1 103.4 90.9 82.4 19.6 129.4 109.7 94.7 113.2 124.1 48.7 50.2 53.9 62.7 49.7 52.3 51.7 49.4 51.5 51.6 53.1 54.3 57.8 60.9 34.5 5.9 45.3 27.9 40.7 142.0 26.7 31.8 29.4 31.6 300.6 48.6 96.0 35.0 25.0 174.1 35.3 41.0 230.9 95.9 76.3 37.0 37.3 58.0 58.0 22.5 10.9 72.2 101.6 54.1 29.6 34.2 39.3 48.5 46.1 76.1 84.6 57.2 13.3 50.4 162.8 37.9 26.6 16.9 60.3 37.2 56.9 9.4 76.5 61.7 70.0 9.0 13.6 55.9 43.0 51.1 38.8 19.1 45.8 146.8 70.7 45.9 65.7 30.8 72.3 98.2 88.3 42.8 29.8 157.2 44.7 224.4 53.0 37.7 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA019950: AB_1855156, HPA062059: AB_2684671" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favorable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 6.0 2.6 3.6 1.8 4.6 1.5 3.6 6.9 5.2 2.0 7.7 3.8 5.4 2.6 3.4 3.7 3.4 2.0 1.8 3.6 4.3 9.2 8.6 3.4 2.6 6.2 4.6 7.4 4.5 6.1 3.0 4.0 6.8 3.8 4.1 5.0 3.6 2.6 2.5 2.1 3.2 2.1 3.5 2.0 3.0 3.8 5.7 2.5 9.3 4.1 3.0 2.1 2.2 4.3 9.8 11.7 7.1 14.1 18.7 9.6 8.9 5.0 19.2 11.3 17.0 23.9 6.7 13.5 6.9 6.9 10.8 12.1 20.8 11.3 10.9 3.2 10.5 6.8 5.9 15.9 10.1 8.8 11.5 7.4 8.3 16.1 16.6 12.3 4.9 14.9 13.3 9.5 10.3 6.3 17.1 6.2 8.4 6.5 14.7 16.7 9.9 21.4 6.0 10.3 14.3 8.0 15.9 6.5 6.0 5.5 8.7 4.3 4.6 7.0 9.2 4.2 7.5 16.6 16.9 13.4 9.5 6.9 7.0 1.1 0.2 1.2 3.8 0.1 3.1 1.0 1.8 3.2 0.8 2.1 2.6 3.0 0.7 4.2 0.1 0.5 0.6 1.3 3.6 4.6 6.9 5.2 3.6 4.3 6.2 4.6 6.8 3.5 5.7 4.3 2.5 9.6 22.9 8.1 3.1 5.2 6.4 1.3 6.2 9.6 5.8 4.2 5.1 8.6 3.1 9.2 14.6 12.8 3.3 13.3 7.9 3.4 0.2 3.5 3.2 3.3 3.6 0.8 8.8 2.9 2.2 4.1 3.1 4.3 6.3 14.4 7.1 20.5 2.4 5.0 7.6 4.2 2.0 1.3 0.4 2.4 3.1 1.2 3.6 3.7 0.4 8.1 7.2 4.5 4.3 3.4 6.6 4.5 4.5 8.9 7.4 9.9 1.2 6.7 0.0 5.9 2.7 12.6 5.7 8.0 2.4 3.6 3.4 4.0 5.5 6.5 PDPN "aggrus, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 135.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Basal respiratory cells: 98.5;Fibroblasts: 123.1;monocytes: 116.3;Muller glia cells: 97.7;Peritubular cells: 62.8" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 149.5;EFO-21: 356.4;HAP1: 253.3;HHSteC: 216.0;NTERA-2: 116.0;SuSa: 119.0;TIME: 242.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" 61.5 3.3 8.9 55.9 9.3 0.0 20.9 13.7 8.1 43.1 23.5 16.6 3.8 25.9 11.3 15.8 33.4 42.1 20.3 8.0 14.6 3.4 0.6 32.4 9.8 24.9 15.6 29.4 6.4 1.1 3.3 135.6 19.1 14.0 10.6 22.7 9.1 14.1 30.0 20.0 15.9 34.5 16.4 0.3 24.7 4.5 22.5 10.3 6.2 11.3 18.5 96.1 25.2 21.2 0.1 0.0 149.5 0.1 0.5 0.0 0.1 2.4 0.1 0.0 0.0 0.0 0.1 0.2 356.4 9.0 0.1 0.7 253.3 44.7 0.0 1.0 46.1 0.1 0.0 0.0 216.0 0.0 0.2 29.5 82.9 18.6 21.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 116.0 0.0 0.6 0.3 0.2 0.1 0.0 4.0 0.1 0.1 0.2 0.0 0.3 119.0 0.1 0.6 242.2 41.8 34.6 0.6 0.1 0.1 0.3 1.0 88.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.9 9.3 13.7 8.1 8.0 14.6 24.9 15.6 19.1 16.4 22.5 21.2 2.4 105.8 11.2 3.9 0.2 14.5 30.4 98.5 14.8 1.4 0.5 19.9 8.4 2.8 18.8 0.0 4.2 2.0 0.1 0.0 0.0 0.5 0.7 1.6 37.6 22.4 0.0 0.0 2.6 0.0 2.1 123.1 0.0 2.8 1.3 3.4 6.4 0.0 6.5 0.0 3.5 0.0 8.2 0.0 14.0 1.8 20.2 5.3 7.2 5.6 116.3 97.7 0.0 19.6 0.2 0.4 0.0 62.8 0.0 15.8 0.0 0.0 5.4 3.4 0.0 17.0 8.4 1.0 8.2 3.9 7.0 2.9 1.3 0.9 0.0 3.4 PDXK "C21orf124, C21orf97, FLJ21324, FLJ31940, MGC15873, PKH, PNK, PRED79" ENSG00000160209 "Pyridoxal kinase" O00764 21 43719094-43762307 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 87.0" "Group enriched" "Detected in all" 4 "Early spermatids: 1717.4;Late spermatids: 4366.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030196, HPA030197, HPA030198, CAB033918" Enhanced Enhanced Nucleoplasm NA NA 830000 "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "CAB033918: AB_2162502, HPA030196: AB_10599735, HPA030197: AB_10601792, HPA030198: AB_10603570" "unprognostic (1.01e-1)" "unprognostic (1.99e-1)" "unprognostic (5.88e-2)" "unprognostic (1.87e-1)" "unprognostic (8.29e-2)" "unprognostic (4.31e-3)" "unprognostic (3.64e-3)" "unprognostic (1.32e-1)" "unprognostic (8.66e-2)" "unprognostic (9.34e-2)" "unprognostic (2.10e-1)" "unprognostic (3.54e-1)" "unprognostic (3.70e-2)" "unprognostic (1.31e-3)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.51e-3)" 25.6 21.8 79.4 7.6 62.2 12.9 18.4 23.9 87.0 14.3 17.5 17.1 14.1 12.3 10.2 19.7 14.0 7.0 15.5 62.5 51.7 50.4 21.5 20.9 7.0 48.8 59.7 19.1 21.3 17.8 37.3 7.8 54.7 17.2 9.4 10.0 22.7 10.6 6.7 13.9 19.7 6.9 34.4 12.5 16.6 23.9 70.5 10.2 19.1 5.4 9.3 10.9 12.6 57.6 43.4 51.9 8.1 15.5 19.4 27.3 9.9 15.2 23.8 14.5 12.1 42.5 65.7 14.4 15.7 21.9 20.0 31.9 15.8 43.4 9.5 16.2 13.4 14.7 60.9 31.7 38.1 14.0 20.6 38.9 40.7 15.3 16.9 23.6 6.9 6.3 26.2 31.9 13.8 29.1 2.0 24.9 22.3 41.9 19.7 16.7 4.8 40.4 62.9 51.9 7.8 9.3 63.3 57.7 23.2 3.3 19.0 19.4 12.5 10.5 20.3 14.2 14.4 19.3 9.8 8.4 43.2 39.9 10.3 0.6 2.4 0.1 0.8 2.2 1.5 0.6 0.8 0.9 1.3 1.7 0.8 0.6 0.6 0.9 4.3 0.6 0.7 1.4 79.4 62.2 23.9 87.0 62.5 51.7 48.8 59.7 54.7 34.4 70.5 57.6 15.8 80.1 66.6 44.1 37.7 28.4 142.4 72.2 27.3 46.3 74.8 53.5 48.0 34.3 73.2 101.2 22.9 42.9 23.6 97.6 180.0 146.4 1717.4 66.9 28.3 36.1 30.1 15.8 49.3 196.6 86.3 39.4 63.2 73.2 31.8 23.8 17.2 54.2 207.6 52.2 48.7 55.4 12.2 58.2 101.0 4366.5 50.1 118.7 42.7 61.8 38.4 14.9 20.6 16.6 13.5 223.4 36.4 54.2 146.4 184.7 108.4 95.7 71.1 43.3 6.6 17.0 35.0 678.1 30.4 60.7 28.4 124.1 27.3 22.1 57.5 239.8 PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Cell type enhanced" "Detected in many" "Early spermatids: 232.9;Excitatory neurons: 313.2;Oligodendrocyte precursor cells: 745.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 24.8;cerebral cortex: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.1;EFO-21: 4.5;SiHa: 11.6;SK-BR-3: 10.6;T-47d: 5.5" "Low region specificity" "Detected in all" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB020784: , HPA036503: AB_2675161, HPA036504: , HPA064387: AB_2685252, HPA076072: " "unprognostic (3.65e-2)" "unprognostic (4.06e-2)" "unprognostic (6.63e-2)" "unprognostic (5.42e-5)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (3.38e-2)" "unprognostic (2.45e-2)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-3)" "unprognostic (4.13e-2)" "unprognostic (6.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.79e-1)" 16.5 0.9 4.5 0.7 24.8 0.1 5.0 0.7 15.7 2.2 10.6 1.4 0.5 2.5 1.9 5.3 2.2 0.9 18.8 4.7 0.3 8.2 0.1 9.0 0.3 4.5 4.3 14.4 1.2 0.6 1.8 10.9 1.0 1.5 0.7 14.8 1.6 1.9 2.5 10.1 0.6 2.4 0.3 0.2 1.7 5.6 4.1 2.6 1.0 4.8 1.7 0.6 2.1 0.0 0.1 0.0 3.1 0.1 0.0 0.0 8.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 4.5 0.0 1.2 4.3 1.7 0.9 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 2.2 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 3.5 0.0 0.1 0.7 11.6 10.6 0.0 2.6 5.5 0.0 0.0 0.0 2.2 0.0 0.5 0.0 0.0 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 24.8 0.7 15.7 4.7 0.3 4.5 4.3 1.0 0.3 4.1 0.0 26.2 44.8 38.6 39.2 0.2 16.8 4.4 14.0 13.6 7.0 10.6 6.9 53.9 0.0 9.3 5.5 98.0 25.5 1.9 0.1 0.0 0.2 232.9 9.7 16.9 14.7 0.0 1.3 313.2 0.2 3.4 8.6 7.7 33.2 1.3 18.7 5.7 0.2 2.2 15.2 113.2 0.0 4.1 0.3 3.1 55.2 7.5 1.0 7.2 87.1 0.2 6.4 0.0 745.0 104.7 3.5 0.0 10.5 0.1 3.5 0.0 8.2 2.8 62.1 46.0 7.3 13.4 12.3 3.8 15.1 18.5 21.1 1.3 46.8 0.0 1.8 PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 595.8" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 280.0;Proximal tubular cells: 1113.8" "Group enriched" "Detected in many" 4 "liver cancer: 27.6;renal cancer: 44.3" "Region enriched" "Detected in many" 7 "cerebellum: 14.7" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Group enriched" "Detected in many" 4 "RPTEC TERT1: 250.0;T-47d: 653.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: AB_1855164, HPA006155: AB_1855163" "unprognostic (4.56e-3)" "unprognostic (3.07e-1)" "unprognostic (8.79e-2)" "unprognostic (4.41e-2)" "unprognostic (9.15e-2)" "unprognostic (2.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.27e-1)" "unprognostic (2.34e-2)" "unprognostic (9.87e-3)" "prognostic favorable (2.54e-7)" "unprognostic (9.90e-2)" "unprognostic (3.02e-1)" "unprognostic (1.00e-3)" "unprognostic (8.87e-2)" 0.6 3.5 0.7 0.5 0.9 0.6 19.6 14.7 2.0 2.4 1.9 4.7 74.8 0.7 15.8 0.2 1.0 22.0 0.4 1.0 0.5 595.8 128.1 0.3 0.7 1.4 0.8 0.3 16.6 0.0 0.6 0.5 1.8 0.3 8.2 3.0 0.4 0.8 0.3 2.6 124.9 0.8 0.4 0.7 2.8 0.6 0.8 0.3 0.3 0.1 0.2 0.2 0.3 1.5 7.6 1.2 0.8 0.8 0.3 0.4 3.0 1.2 0.3 0.2 1.0 106.6 1.0 0.7 1.3 5.9 0.5 3.4 0.2 0.6 0.6 10.3 2.0 0.9 2.8 45.7 0.0 1.1 0.9 0.3 0.7 0.4 0.2 0.8 0.0 0.4 0.8 1.6 0.8 6.0 0.7 1.4 1.2 1.5 3.6 0.4 7.3 1.6 250.0 0.3 0.6 6.7 1.7 1.8 0.2 6.4 653.8 0.9 0.5 1.3 1.3 0.9 1.1 8.8 1.2 0.6 1.0 0.6 0.5 0.1 0.1 0.0 0.7 0.1 0.2 0.6 0.2 0.8 0.0 0.4 0.2 0.3 0.1 4.2 0.0 0.5 0.0 0.3 0.7 0.9 14.7 2.0 1.0 0.5 1.4 0.8 1.8 0.4 0.8 1.5 0.2 0.0 0.0 2.0 4.1 0.1 0.0 0.1 0.0 0.4 20.2 3.3 0.5 72.9 0.0 57.0 0.0 0.0 0.9 27.4 138.9 1.2 8.6 1.1 0.5 0.4 6.6 0.0 2.8 2.0 0.1 0.5 0.5 4.9 0.0 0.2 1.1 47.9 0.2 0.0 1.9 7.8 0.0 0.9 0.3 9.0 0.0 4.9 0.0 1.9 0.0 0.3 2.1 3.0 0.7 1.5 7.4 0.0 0.0 0.1 280.0 1113.8 0.1 0.5 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.1 4.1 4.3 6.5 0.1 PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 246.3;monocytes: 267.6;Muller glia cells: 315.8" "Cancer enhanced" "Detected in all" "glioma: 466.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol Nucleoplasm "HPA028356: AB_10602814, HPA070820: AB_2732166" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" 190.2 82.2 863.3 121.7 900.6 16.6 142.7 908.1 949.4 110.1 612.5 146.5 31.7 124.5 83.4 119.2 104.2 88.2 241.9 884.6 939.2 112.0 41.2 147.9 75.5 1028.2 1010.2 80.4 39.6 85.4 80.0 102.3 981.5 112.2 58.5 461.4 80.8 119.4 61.1 105.6 64.8 194.6 933.0 103.2 75.8 80.5 915.2 40.7 83.5 84.5 96.9 133.4 110.2 1106.4 139.2 46.8 190.5 82.5 344.5 191.5 63.6 593.2 503.3 471.6 328.5 103.7 72.3 63.4 210.9 729.4 226.6 146.4 71.5 181.7 365.3 34.4 40.2 52.4 32.5 26.7 423.9 17.8 62.0 161.8 100.7 260.2 328.5 259.6 360.7 45.7 55.1 111.8 640.6 68.3 21.0 41.1 127.0 160.9 134.3 34.4 200.6 43.8 173.0 71.0 38.0 100.0 310.4 207.6 179.9 409.4 128.1 122.6 487.7 311.3 246.4 234.4 254.5 88.1 59.5 118.7 287.1 33.2 450.8 1.3 39.3 5.2 8.4 78.2 6.5 18.9 6.2 6.9 56.7 13.5 3.8 4.2 1.8 7.9 38.7 25.0 7.9 14.9 863.3 900.6 908.1 949.4 884.6 939.2 1028.2 1010.2 981.5 933.0 915.2 1106.4 137.8 16.0 29.9 40.5 38.6 80.2 124.2 21.8 33.6 172.1 76.9 60.2 246.3 11.5 24.7 5.5 73.0 21.8 13.7 12.7 29.4 74.7 65.4 36.4 33.7 125.1 12.0 7.4 24.8 46.3 61.1 81.5 17.9 85.9 31.1 17.2 89.3 6.5 63.3 92.5 19.1 12.0 8.2 42.6 234.6 55.4 66.8 68.9 74.7 14.0 267.6 315.8 8.2 12.1 48.3 102.5 4.7 109.9 14.8 119.4 5.4 18.3 13.8 129.2 46.0 69.4 78.3 16.5 4.1 42.7 73.3 45.3 19.4 18.5 12.8 178.8 PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916434 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.6;Endothelial cells: 30.6;Hepatic stellate cells: 40.0;Leydig cells: 44.4;Peritubular cells: 35.7;Sertoli cells: 26.3;Smooth muscle cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.5;HBEC3-KT: 29.9;HHSteC: 21.6;HUVEC TERT2: 52.2;TIME: 85.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA 62000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cell Junctions" Centrosome "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" 19.0 5.0 2.5 2.3 3.0 2.3 12.9 1.2 4.1 12.3 2.0 4.5 1.6 10.0 1.1 2.6 9.1 7.4 8.7 1.2 1.7 4.8 2.1 11.8 3.8 2.0 2.3 9.1 2.3 1.7 3.4 11.7 2.3 4.7 0.9 0.4 2.9 3.7 5.7 4.2 4.1 4.6 1.1 7.0 3.7 3.0 2.9 1.4 9.7 7.6 1.1 6.0 7.3 1.4 0.5 2.9 0.8 0.0 0.0 3.7 0.1 11.7 19.5 4.8 2.8 0.3 0.5 0.0 0.6 8.7 0.4 0.2 0.0 29.9 1.3 0.2 0.0 14.8 0.7 0.8 21.6 0.1 0.0 11.3 0.1 6.5 1.5 1.0 52.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 6.9 0.0 0.0 85.2 0.1 6.4 2.6 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 3.0 1.2 4.1 1.2 1.7 2.0 2.3 2.3 1.1 2.9 1.4 44.6 0.0 3.2 0.0 0.4 0.9 0.1 0.7 1.2 2.4 0.6 1.3 7.5 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.2 0.2 2.5 30.6 1.8 5.7 0.0 0.4 0.1 10.1 1.5 0.4 1.3 0.1 40.0 0.4 0.5 0.0 0.0 2.3 0.0 1.6 1.5 3.5 44.4 3.0 5.4 12.2 0.4 0.2 0.0 0.0 0.0 1.2 0.0 35.7 0.0 0.2 0.0 0.1 0.2 0.2 26.3 1.7 34.2 1.5 1.5 0.2 1.1 0.3 0.3 1.1 0.3 0.2 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 160.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 91.0;Proximal enterocytes: 49.5;Proximal tubular cells: 79.1" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 38.3;RPTEC TERT1: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" 25.4 5.4 2.7 2.9 3.1 7.1 10.2 3.8 2.9 4.5 6.0 8.7 26.0 3.3 4.1 3.1 8.1 9.7 2.4 2.7 2.8 33.9 160.2 6.4 3.9 3.2 3.1 4.1 4.8 7.2 3.2 1.0 3.3 5.0 7.5 2.2 5.6 3.4 6.8 4.2 20.1 3.2 2.6 3.0 3.9 0.5 3.0 3.4 16.1 5.2 3.8 2.3 2.3 3.7 6.0 6.6 2.6 0.1 15.7 5.7 3.1 1.4 3.3 3.7 6.3 7.6 17.1 0.1 11.9 3.5 9.2 1.4 7.5 8.7 6.5 9.5 7.7 7.8 3.6 38.3 15.7 2.0 5.1 5.0 6.1 3.9 5.5 5.6 3.8 4.6 3.3 8.6 8.2 4.4 2.4 2.2 4.8 0.1 4.9 5.3 5.0 0.9 35.9 1.0 3.6 5.2 3.6 7.4 15.6 6.2 8.6 6.5 0.0 2.4 2.5 6.0 4.3 9.8 8.9 3.1 5.3 2.8 5.6 1.2 4.2 1.5 6.5 1.6 7.7 4.3 8.8 7.5 1.5 5.7 9.2 6.1 4.5 9.9 2.3 0.2 16.6 4.1 2.7 3.1 3.8 2.9 2.7 2.8 3.2 3.1 3.3 2.6 3.0 3.7 4.3 6.4 13.6 6.5 7.0 3.7 4.7 4.0 3.4 10.8 2.4 2.9 3.7 35.8 3.4 29.5 14.6 3.9 5.9 11.5 13.7 13.2 0.1 10.1 2.7 3.9 7.2 9.4 15.4 3.8 7.3 5.0 7.7 6.3 1.3 2.0 6.8 91.0 9.6 3.3 18.4 8.0 6.1 4.7 3.7 0.3 5.6 5.5 10.6 8.4 27.4 10.1 9.2 8.5 10.6 5.0 17.7 8.2 5.9 2.0 49.5 79.1 13.1 6.4 0.0 6.6 4.4 0.1 1.6 4.9 2.8 1.6 11.4 1.9 14.6 2.7 PEDS1 "CarF, Kua, TMEM189" ENSG00000240849 "Plasmanylethanolamine desaturase 1" A5PLL7 20 50118254-50153734 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 86.8;Extravillous trophoblasts: 167.6;Hofbauer cells: 38.6;Syncytiotrophoblasts: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059549 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA059549: AB_2684059" "unprognostic (3.11e-2)" "unprognostic (7.04e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (2.03e-3)" "unprognostic (7.00e-2)" "unprognostic (2.19e-2)" "unprognostic (1.35e-1)" "unprognostic (8.63e-2)" "unprognostic (5.79e-2)" "prognostic unfavorable (5.79e-11)" "unprognostic (1.85e-1)" "unprognostic (1.20e-1)" "unprognostic (9.46e-2)" "unprognostic (4.42e-2)" 13.2 14.0 19.6 7.3 24.0 5.7 10.4 25.3 24.3 12.7 15.8 18.4 8.7 13.8 10.7 26.0 9.1 7.2 20.8 19.6 20.8 9.3 17.8 13.7 6.0 25.8 24.4 5.5 9.3 12.8 5.8 17.6 24.1 11.6 7.1 2.2 12.4 13.5 16.9 22.9 9.8 21.8 21.0 10.0 15.1 6.3 23.3 7.8 7.7 16.3 7.4 15.4 15.1 29.1 19.6 17.7 20.7 16.3 30.7 23.0 34.6 13.6 12.6 27.8 15.6 48.6 30.5 7.2 21.2 12.8 39.7 52.8 10.4 27.4 10.0 3.8 8.0 9.3 24.5 41.6 17.3 15.1 24.2 19.7 62.7 15.6 16.4 13.4 33.6 12.2 9.8 10.2 9.5 17.3 12.0 38.1 10.1 50.1 18.3 9.7 15.9 7.8 53.7 28.4 10.8 7.1 15.4 52.2 32.4 20.3 8.3 21.2 26.8 23.1 12.1 15.1 13.5 7.5 13.6 2.9 19.9 11.1 19.1 4.9 5.3 6.2 3.1 10.2 2.6 1.8 3.5 2.6 5.6 1.5 2.9 3.4 2.0 4.0 14.0 3.6 5.6 3.8 19.6 24.0 25.3 24.3 19.6 20.8 25.8 24.4 24.1 21.0 23.3 29.1 8.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 86.8 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 167.6 6.3 0.0 0.0 0.0 0.0 0.0 0.0 38.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 50.1 1.2 0.0 0.0 0.0 PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 166.2;liver: 267.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 122.9;Hepatocytes: 220.1;Peritubular cells: 346.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042375, HPA073930" Approved Supported "Endoplasmic reticulum,Vesicles,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum, Mitochondria" "Vesicles, Cytosol" "HPA042375: AB_10796905, HPA073930: " "unprognostic (1.39e-2)" "unprognostic (3.43e-1)" "unprognostic (2.43e-2)" "prognostic favorable (6.77e-6)" "unprognostic (2.85e-1)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (3.41e-2)" "unprognostic (5.47e-3)" "unprognostic (2.67e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.66e-2)" "unprognostic (7.60e-2)" 71.6 33.9 13.2 5.2 13.6 9.2 92.7 16.3 20.0 47.4 12.7 13.6 15.0 36.9 166.2 26.8 26.5 5.4 24.5 13.0 15.2 30.2 267.4 25.8 5.2 14.9 15.3 27.9 32.2 13.3 24.7 7.3 16.8 30.8 3.4 2.8 27.1 24.0 29.5 34.3 13.7 6.8 15.1 12.8 19.5 40.8 14.2 5.6 33.5 10.7 4.5 21.1 24.2 17.2 34.3 64.7 16.5 43.4 34.6 23.8 25.1 21.6 19.0 28.5 22.4 38.2 22.6 29.8 38.1 21.9 21.6 39.9 24.6 12.8 7.2 22.2 86.9 14.8 33.2 55.4 38.4 13.5 21.4 24.9 26.7 19.2 29.1 9.7 15.7 41.3 14.6 12.3 12.9 66.0 23.9 24.2 23.2 65.5 52.4 22.2 26.7 27.5 24.1 12.5 16.7 39.5 15.3 10.1 39.2 31.5 15.6 5.1 13.9 28.1 28.2 47.4 18.9 17.0 12.1 5.5 25.9 18.5 23.6 1.9 41.1 2.1 16.9 39.0 24.8 23.5 22.2 21.5 30.5 28.3 17.2 19.4 3.1 29.3 28.0 27.7 22.4 21.3 13.2 13.6 16.3 20.0 13.0 15.2 14.9 15.3 16.8 15.1 14.2 17.2 38.1 16.0 17.5 4.9 12.4 18.2 21.0 27.9 39.3 4.5 33.0 45.1 15.5 11.5 24.9 27.6 0.0 19.5 5.9 9.3 17.6 33.3 2.9 21.8 122.9 18.5 68.8 17.1 5.4 38.5 21.6 30.4 8.2 23.8 12.7 52.4 10.4 220.1 23.5 5.0 6.8 30.9 24.4 13.7 12.2 14.9 94.8 11.2 21.4 3.7 5.7 34.7 2.1 9.5 4.0 25.7 10.8 346.8 15.3 35.1 21.7 32.3 14.2 6.1 6.6 20.0 23.6 21.0 24.9 39.5 18.2 14.6 12.5 49.3 24.1 23.8 PER2 KIAA0347 ENSG00000132326 "Period circadian regulator 2" O15055 2 238244044-238290102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053136, HPA060510" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA053136: , HPA060510: AB_2684298" "unprognostic (1.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.88e-2)" "unprognostic (9.28e-2)" "unprognostic (2.52e-1)" "prognostic favorable (2.29e-4)" "unprognostic (2.47e-2)" "unprognostic (2.17e-2)" "unprognostic (3.59e-3)" "unprognostic (3.59e-2)" "unprognostic (1.76e-2)" "unprognostic (2.13e-1)" "unprognostic (6.81e-2)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (2.58e-1)" "unprognostic (5.22e-2)" 12.2 3.3 4.7 5.0 5.2 8.4 14.2 7.2 5.8 11.9 2.4 7.6 5.1 10.2 5.7 13.6 7.9 12.3 5.7 5.7 5.1 3.9 12.4 7.1 4.7 5.2 5.7 7.8 14.4 4.2 9.0 2.9 4.4 9.3 6.2 5.1 14.1 8.9 11.4 17.0 8.0 4.9 5.4 4.8 13.4 11.8 4.7 4.1 8.8 7.6 6.2 8.7 8.2 4.7 1.6 11.7 2.4 4.2 0.1 1.2 8.2 1.1 4.1 1.5 1.4 1.8 5.8 10.3 1.2 2.7 1.5 8.6 2.4 3.5 2.2 2.9 1.7 9.1 6.2 8.2 2.0 13.8 9.2 1.6 8.3 1.8 6.1 1.5 0.8 4.2 4.5 6.3 1.3 7.7 6.9 15.2 3.5 7.6 2.3 16.5 5.5 3.3 1.5 3.3 9.7 1.2 2.9 6.3 1.8 0.7 5.9 8.5 2.1 3.6 4.2 2.8 4.1 7.1 1.8 12.3 6.7 5.9 4.5 2.1 1.2 0.3 1.0 2.2 1.6 1.5 1.6 1.2 1.4 1.5 1.5 1.6 1.0 1.2 2.1 1.8 1.2 0.3 4.7 5.2 7.2 5.8 5.7 5.1 5.2 5.7 4.4 5.4 4.7 4.7 24.9 16.0 30.1 18.6 9.9 73.9 61.7 21.3 38.1 20.6 67.8 33.8 5.7 31.5 46.9 27.6 2.1 9.2 27.0 22.5 7.9 7.5 9.6 69.7 30.1 15.6 24.6 6.9 20.9 10.4 6.3 39.8 52.5 86.1 9.5 3.3 11.4 35.8 3.9 11.8 13.9 35.1 18.3 10.1 25.3 4.7 11.1 12.4 24.9 5.6 5.3 13.5 2.1 9.0 7.2 7.6 35.3 18.4 10.9 15.0 10.9 5.5 44.2 7.8 6.6 110.1 32.2 31.3 17.0 38.4 85.4 13.0 13.6 3.7 36.9 33.9 PEX11A "MGC119947, MGC138534, PEX11-ALPHA" ENSG00000166821 "Peroxisomal biogenesis factor 11 alpha" O75192 15 89677764-89690783 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 38.7;Late spermatids: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (1.40e-1)" "unprognostic (6.17e-2)" "unprognostic (6.80e-3)" "unprognostic (2.82e-2)" "unprognostic (2.38e-1)" "unprognostic (3.24e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-2)" "unprognostic (5.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.32e-2)" 25.6 10.4 7.9 3.4 8.3 0.8 20.0 6.9 8.5 7.2 12.8 14.5 16.3 6.0 10.5 6.5 9.6 5.4 8.1 7.9 8.7 11.7 39.1 6.1 2.5 7.1 7.8 13.1 11.8 10.0 5.5 3.6 7.2 18.3 12.0 12.7 11.3 10.1 17.9 5.4 12.2 5.5 7.2 4.1 11.3 11.4 9.0 2.3 10.9 12.0 3.7 9.2 6.1 7.9 10.2 6.1 4.6 0.3 23.4 8.4 3.7 5.0 8.5 7.4 12.0 4.3 11.9 4.7 5.5 5.8 10.6 13.3 0.0 7.6 8.5 7.5 16.8 7.1 7.2 6.0 16.8 4.7 2.4 10.4 9.2 4.3 7.1 5.8 5.2 4.6 0.1 1.8 5.6 10.2 0.0 0.6 2.6 20.6 11.1 0.0 0.0 4.2 6.1 6.8 3.4 8.7 16.0 54.4 15.5 8.3 14.4 4.4 4.7 4.9 4.8 13.2 4.0 5.3 9.5 0.2 11.9 0.7 4.3 1.2 0.7 2.3 3.6 1.0 2.0 1.6 1.8 2.0 1.8 0.9 2.2 2.5 0.8 3.1 0.7 0.4 1.7 1.5 7.9 8.3 6.9 8.5 7.9 8.7 7.1 7.8 7.2 7.2 9.0 7.9 1.5 6.4 8.4 12.4 2.0 1.8 9.3 5.2 7.4 8.6 15.3 10.9 8.7 10.0 11.4 5.5 2.1 10.8 1.3 22.1 5.9 7.6 24.8 7.1 5.5 3.1 3.6 0.8 3.0 4.6 7.1 4.6 3.1 5.2 1.3 6.2 4.6 38.7 4.0 18.5 3.5 8.9 6.1 3.5 0.8 39.0 5.3 1.6 3.6 2.8 1.9 14.5 1.0 3.5 3.5 5.5 11.6 2.6 0.6 11.5 20.7 12.6 16.2 9.7 0.0 6.4 4.6 22.6 8.7 5.0 2.0 2.7 1.5 11.0 11.8 11.9 PEX19 "D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1" ENSG00000162735 "Peroxisomal biogenesis factor 19" P40855 1 160276807-160286348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044837, HPA051966" Supported Supported Peroxisomes NA NA 7900 "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Peroxisomes "HPA044837: AB_10962496, HPA051966: AB_2681677" "unprognostic (1.49e-2)" "unprognostic (2.26e-1)" "unprognostic (3.42e-1)" "unprognostic (4.80e-3)" "unprognostic (3.89e-2)" "unprognostic (3.88e-2)" "unprognostic (3.79e-1)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.53e-2)" "unprognostic (8.06e-2)" "unprognostic (1.00e-1)" "prognostic favorable (2.92e-5)" "unprognostic (3.46e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-2)" "unprognostic (1.24e-2)" 79.3 25.7 21.1 14.5 22.5 12.3 36.5 22.2 23.5 20.3 15.6 22.6 19.4 18.2 25.0 24.9 22.9 19.6 39.4 21.5 22.7 33.1 109.1 21.6 16.6 22.3 23.5 23.6 17.2 40.4 15.0 21.9 23.5 28.0 23.2 30.9 21.3 26.6 66.2 18.2 18.8 16.7 22.1 16.7 20.0 16.8 22.7 21.0 34.3 84.8 20.5 23.9 15.2 24.5 31.2 18.9 69.8 22.4 59.8 57.8 53.0 25.3 51.3 44.6 35.3 35.1 37.2 37.8 40.9 37.3 26.3 29.7 34.2 44.0 35.3 32.3 17.3 26.6 26.5 36.3 46.9 48.6 32.6 84.7 51.0 60.0 38.6 35.8 32.2 51.4 40.8 27.9 50.0 17.8 37.0 15.8 50.3 38.6 48.2 45.7 34.4 45.5 45.8 61.8 23.2 38.3 98.3 49.5 37.4 71.3 48.1 48.2 24.8 26.5 31.1 29.9 30.1 42.5 57.9 68.6 43.1 20.9 38.9 9.1 5.5 5.0 5.8 8.9 4.2 5.0 2.8 3.5 5.5 1.9 4.0 3.7 2.2 4.7 6.6 3.4 4.2 2.3 21.1 22.5 22.2 23.5 21.5 22.7 22.3 23.5 23.5 22.1 22.7 24.5 16.4 9.6 20.6 9.1 12.7 9.9 21.0 15.4 13.1 18.8 18.9 16.4 45.6 20.0 11.3 16.5 10.4 30.0 6.9 25.4 49.0 22.6 6.6 12.0 13.7 13.6 11.4 15.6 8.6 14.8 51.2 18.4 13.3 12.0 16.5 15.6 20.0 60.1 30.1 25.2 9.0 11.5 0.0 15.7 7.0 3.1 21.8 15.0 21.4 6.5 24.9 39.0 12.3 6.0 11.5 20.2 17.2 29.3 9.5 18.5 29.8 40.7 11.8 12.7 32.9 14.6 16.2 17.8 25.3 15.0 9.9 38.7 12.5 18.2 15.7 25.2 PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 28.3;liver: 50.2;skeletal muscle: 111.6;tongue: 40.8" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 15.9" "Cancer enriched" "Detected in some" 11 "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.5;Hep G2: 3.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (1.17e-2)" "unprognostic (4.38e-3)" "unprognostic (1.64e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (3.26e-3)" "unprognostic (2.88e-1)" "unprognostic (5.36e-3)" "unprognostic (5.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.16e-4)" "unprognostic (1.96e-3)" 28.3 0.5 0.4 0.1 0.5 0.4 9.2 0.3 0.5 0.1 0.1 0.4 0.1 0.1 0.6 1.1 0.1 0.3 0.3 0.4 0.4 1.1 50.2 0.2 0.5 0.5 0.4 0.0 1.2 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.7 0.2 111.6 0.8 0.5 0.1 0.4 0.3 0.4 0.4 0.4 0.4 1.0 40.8 0.6 0.2 0.2 0.5 0.2 0.1 0.2 0.4 8.5 0.1 0.6 0.0 0.1 0.1 0.0 0.5 0.1 0.4 0.1 0.0 0.4 0.3 0.1 0.2 0.3 0.3 0.7 0.2 0.1 3.2 0.0 0.0 0.3 0.1 0.4 0.0 0.2 0.0 0.0 0.8 0.1 1.4 0.1 0.5 0.4 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.0 0.2 0.2 0.1 0.3 1.0 0.1 0.7 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.7 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.5 0.4 0.4 0.5 0.4 0.4 0.4 0.4 0.5 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 15.9 0.1 0.0 1.5 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 334.6;skeletal muscle: 621.3" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Collecting duct cells: 195.0;Langerhans cells: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 296.2;RPTEC TERT1: 181.8;T-47d: 192.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: AB_2678717" "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 334.6 22.7 66.1 72.2 81.2 246.0 153.8 75.4 66.6 30.2 22.1 22.2 19.4 24.0 11.1 51.3 37.7 59.9 21.9 62.8 105.8 243.9 32.8 67.7 24.5 145.7 100.9 24.2 21.0 10.1 39.6 20.0 100.9 20.2 8.9 31.5 40.4 49.5 621.3 53.6 22.9 16.9 90.1 50.2 26.1 13.9 91.8 15.1 10.9 30.4 28.2 63.9 40.3 105.6 22.0 296.2 23.1 18.8 85.2 10.5 12.2 31.6 22.5 22.9 35.5 14.1 78.0 37.2 20.2 13.8 18.0 69.0 24.9 50.2 26.3 44.6 17.3 22.1 16.2 5.2 7.2 21.6 32.2 7.6 16.4 39.5 9.5 58.3 44.9 25.6 16.6 13.6 18.6 35.7 15.3 20.3 22.5 31.1 20.5 34.3 11.3 14.7 181.8 11.1 21.9 8.9 22.9 24.7 45.8 39.5 192.0 25.2 57.0 23.9 22.0 3.1 38.7 27.8 10.4 33.7 65.8 25.0 37.4 2.9 7.5 7.7 2.2 9.2 5.7 1.8 4.2 2.9 4.7 1.6 3.0 3.0 26.4 1.2 5.5 2.9 4.3 4.3 66.1 81.2 75.4 66.6 62.8 105.8 145.7 100.9 100.9 90.1 91.8 105.6 37.1 76.9 55.1 153.8 27.2 102.6 16.7 21.5 37.5 6.4 37.1 36.8 19.5 22.8 32.1 195.0 52.1 0.4 37.0 14.9 0.0 54.7 5.0 41.1 18.9 32.9 8.5 1.3 42.8 25.7 6.9 30.8 33.1 64.3 44.2 72.5 8.9 15.8 20.6 6.7 19.4 6.6 18.3 88.0 132.3 9.5 2.8 122.2 46.2 41.2 19.6 0.3 4.1 14.1 31.9 59.6 5.2 7.2 25.3 4.2 5.4 2.4 19.2 1.9 0.0 58.5 24.4 0.6 2.5 20.9 63.9 1.0 61.7 12.4 8.1 14.7 PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137718 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 277.0" "Cell type enhanced" "Detected in many" "Early spermatids: 459.8;Late spermatids: 516.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018257, HPA056484" Uncertain Supported Cytosol No No 1900000 "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA018257: AB_10960391, HPA056484: AB_2683147" "unprognostic (1.16e-1)" "unprognostic (2.41e-3)" "unprognostic (5.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.55e-4)" "prognostic unfavorable (8.72e-6)" "unprognostic (1.36e-3)" "unprognostic (2.38e-1)" "unprognostic (8.51e-2)" "unprognostic (2.37e-2)" "unprognostic (8.82e-2)" "unprognostic (6.02e-3)" "unprognostic (2.60e-2)" "unprognostic (9.74e-2)" "unprognostic (2.06e-1)" "unprognostic (4.54e-3)" 35.0 11.5 41.6 41.5 39.3 14.4 23.5 13.8 49.9 26.3 61.7 43.8 48.8 55.5 5.6 67.1 34.9 34.1 128.6 60.4 65.0 44.6 4.7 19.1 32.5 30.7 50.9 19.1 15.9 15.2 29.9 15.5 58.0 35.6 30.7 277.0 39.8 62.0 70.4 40.3 59.6 44.1 8.3 19.1 36.8 141.1 47.0 29.7 38.5 21.0 21.2 64.7 42.8 31.7 314.8 420.2 25.9 0.6 26.8 56.9 336.9 187.2 66.6 186.2 222.8 444.5 320.4 37.0 147.8 134.9 174.9 243.0 141.7 292.3 173.1 102.1 111.0 132.0 189.1 24.2 65.2 53.7 203.4 27.0 61.2 190.0 96.0 273.7 367.8 153.7 37.0 1.3 195.7 239.8 182.5 44.4 42.9 133.9 149.3 138.8 46.9 150.1 185.7 115.9 69.5 64.7 133.7 111.0 172.0 307.8 93.7 80.3 449.2 124.6 65.3 380.5 199.3 195.4 200.1 135.7 331.0 98.0 78.5 30.8 8.5 2.9 26.8 4.2 21.2 13.7 26.2 25.0 14.5 15.3 9.6 15.4 1.3 26.7 1.6 22.5 37.6 16.5 41.6 39.3 13.8 49.9 60.4 65.0 30.7 50.9 58.0 8.3 47.0 31.7 30.5 3.2 7.0 128.6 14.8 28.7 58.5 96.8 14.8 40.4 10.3 7.7 147.4 8.6 57.9 64.4 54.2 7.8 16.3 72.6 43.0 115.7 459.8 41.2 9.0 36.0 37.2 10.3 49.4 10.8 205.8 25.9 35.7 63.8 55.9 25.8 14.6 0.7 33.9 42.1 25.9 23.1 124.1 7.6 31.4 516.3 7.5 14.3 19.6 15.0 15.4 113.1 16.5 16.1 6.7 116.8 57.2 6.8 14.2 80.9 53.2 5.9 62.6 133.4 13.1 43.2 34.6 149.4 3.5 25.1 22.6 26.5 28.8 11.2 28.9 64.2 PGA5 ENSG00000256713 "Pepsinogen A5" P0DJD9 11 61241175-61251444 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2014 "stomach 1: 39870.8" "Cell type enriched" "Detected in some" 77 "Exocrine glandular cells: 4383.1" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 29 "classical monocyte: 1.8;intermediate monocyte: 4.3;non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 44 "monocytes: 4.3" "Cell line enriched" "Detected in some" 19 "BJ hTERT+: 28.8" HPA046875 Supported "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA046875: AB_2679851" "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" 19.7 4.4 0.3 1.1 0.3 0.0 4.5 0.1 0.6 4.0 0.0 6.2 0.6 1.9 0.0 7.0 5.1 0.1 3.5 0.7 0.0 2.4 7.0 5.4 0.0 0.1 0.0 2.6 8.2 0.0 3.8 0.5 0.1 1.8 0.1 1.5 2.5 0.5 1.9 2.1 2.1 0.9 0.0 3.9 39870.8 2.3 0.0 0.2 3.1 0.2 0.1 2.3 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.3 0.3 0.3 0.1 0.6 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 4383.1 0.0 0.1 56.6 0.0 0.0 0.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 5.1 0.0 1.6 0.9 1.3 0.0 0.0 1.0 25.1 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "monocytes: 214.9;Squamous epithelial cells: 496.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Cell line enhanced" "Detected in all" "A549: 1445.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" 115.8 51.0 49.5 59.8 49.2 400.2 89.0 52.9 49.3 75.9 52.5 52.9 91.6 23.1 41.9 572.4 30.0 94.2 34.3 47.4 54.3 53.2 81.3 88.5 38.1 57.0 54.6 35.7 32.0 52.7 43.8 47.4 55.4 30.4 46.3 49.1 133.7 22.9 34.7 50.0 70.7 35.0 49.7 110.4 61.4 68.3 59.2 53.6 71.8 28.2 73.8 61.8 126.9 52.0 191.5 1445.2 319.3 340.6 445.4 274.0 71.8 124.8 185.9 144.4 195.3 219.2 190.4 163.5 151.0 109.2 202.4 148.0 225.6 192.1 96.4 127.5 199.9 227.8 264.3 452.1 136.3 390.9 249.7 196.5 92.2 229.4 55.5 186.9 344.0 223.0 305.3 145.7 183.5 202.5 321.4 179.4 194.7 221.0 109.1 252.7 298.1 312.2 199.6 105.5 178.0 154.1 99.1 153.5 137.5 196.7 173.3 308.5 369.3 81.1 149.6 98.3 134.5 111.6 256.0 323.5 175.1 393.9 73.6 1060.2 321.0 1074.7 23.2 137.7 26.5 33.1 21.4 20.8 144.6 23.3 21.1 22.3 332.6 19.7 105.6 98.7 23.1 225.0 49.5 49.2 52.9 49.3 47.4 54.3 57.0 54.6 55.4 49.7 59.2 52.0 7.4 19.2 35.0 11.8 24.9 13.0 30.8 78.0 70.6 7.8 30.4 18.5 11.0 50.1 73.2 20.2 18.8 134.6 29.8 24.3 52.8 52.1 10.9 17.8 18.6 22.6 23.4 55.7 8.6 40.3 40.7 37.5 41.8 24.5 25.9 53.9 16.1 66.2 134.6 1.7 12.6 30.2 59.0 163.8 30.9 13.4 17.1 150.9 17.8 4.7 214.9 16.5 10.3 13.6 9.0 38.7 26.7 10.5 41.9 43.5 66.6 55.1 46.2 20.2 19.7 23.4 21.5 41.5 38.4 496.0 16.6 81.3 19.4 27.3 51.7 76.1 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 258.8" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 168.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 5 "MCF7: 8.1;T-47d: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" NA NA 87000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 2: Hepatocytes - Metabolism" "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 258.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.4 0.4 0.2 1.6 1.7 1.6 0.2 0.9 0.8 0.1 0.0 2.2 2.3 1.6 0.5 5.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.2 0.5 0.0 0.0 4.1 1.5 0.2 4.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.9 168.7 0.3 0.0 0.4 0.0 0.0 2.2 0.0 3.1 0.3 1.9 8.8 0.0 1.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 14.1 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.0 7.6 0.0 0.0 0.1 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1559.1;tongue: 788.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 238.4;Extravillous trophoblasts: 185.9;Hepatocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 21000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: AB_2679625" "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 113.7 70.8 31.6 20.7 34.7 21.5 57.4 34.3 38.4 33.9 53.1 58.9 60.8 22.9 19.2 49.3 17.0 30.3 178.9 31.4 34.0 52.2 279.8 42.6 14.7 44.7 34.1 51.0 112.2 65.3 31.8 26.9 32.7 46.6 49.9 22.6 41.8 49.7 1559.1 30.6 55.1 41.4 31.9 14.7 30.6 11.1 36.5 14.3 27.5 788.0 19.4 38.4 22.1 30.2 113.4 47.0 17.3 57.0 111.0 81.4 138.6 45.7 61.8 48.9 79.0 38.8 51.3 35.8 93.2 71.2 107.4 26.5 24.0 96.3 55.9 44.0 32.1 75.3 72.6 40.3 91.6 66.8 4.3 103.4 60.7 57.1 88.5 129.8 29.6 36.3 0.1 46.3 78.8 6.9 19.6 36.7 78.3 3.4 73.9 26.8 80.0 11.8 70.0 35.3 10.4 66.7 100.0 103.0 157.4 78.6 32.4 25.2 3.1 71.6 36.0 64.0 39.4 29.1 45.5 57.8 117.0 58.0 31.5 46.0 33.2 49.2 40.5 22.4 32.7 22.4 23.5 31.0 48.4 11.8 21.0 24.7 38.7 43.9 21.2 13.9 20.4 35.4 31.6 34.7 34.3 38.4 31.4 34.0 44.7 34.1 32.7 31.9 36.5 30.2 8.4 93.0 29.4 48.3 16.9 17.8 29.0 58.8 47.8 9.2 33.8 21.8 139.2 48.6 24.2 16.5 10.4 76.6 14.2 81.8 88.0 55.9 32.0 8.2 12.1 12.7 13.1 5.7 17.9 238.4 185.9 37.0 27.0 13.5 5.1 134.3 15.0 214.4 24.6 0.0 26.3 47.5 20.3 17.0 10.8 8.5 22.1 13.5 26.6 4.7 32.8 75.8 29.9 32.2 9.8 70.5 31.6 38.0 40.4 29.2 90.2 74.8 17.0 11.4 13.1 53.4 25.5 5.6 10.1 57.3 18.2 58.8 19.0 20.2 81.5 19.0 PHACTR2 "C6orf56, KIAA0680" ENSG00000112419 "Phosphatase and actin regulator 2" O75167 6 143536845-143831185 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 164.2;placenta: 83.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 82.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031719, HPA031720, HPA031725" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA031719: AB_10696055, HPA031720: AB_10670553, HPA031725: AB_10610279" "unprognostic (3.25e-3)" "unprognostic (1.07e-1)" "unprognostic (4.39e-2)" "unprognostic (5.25e-2)" "unprognostic (1.90e-2)" "unprognostic (8.38e-2)" "unprognostic (3.19e-2)" "unprognostic (9.92e-2)" "unprognostic (7.46e-2)" "unprognostic (3.61e-2)" "unprognostic (2.49e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.99e-4)" "unprognostic (3.60e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-2)" "unprognostic (1.17e-1)" 11.6 25.4 7.0 7.8 9.0 7.6 5.5 4.3 5.7 8.1 164.2 8.5 7.5 9.9 3.6 22.0 5.7 8.4 12.4 10.0 4.9 5.9 7.9 15.7 7.8 12.3 10.3 6.5 4.9 13.1 4.0 83.8 15.1 10.3 8.5 2.7 6.0 6.9 4.5 2.7 6.1 9.8 3.5 13.5 12.0 6.5 16.5 2.7 15.5 7.3 6.7 7.6 6.4 4.5 21.9 13.5 3.6 26.6 3.7 8.0 15.3 18.0 27.2 7.7 9.6 23.9 9.5 1.2 47.5 51.7 5.4 6.5 2.0 17.9 9.1 18.1 8.5 35.5 14.7 14.0 6.1 9.1 10.5 11.2 9.8 7.7 24.9 11.8 47.0 6.7 10.2 0.1 12.4 24.0 1.3 2.1 26.8 7.7 3.8 3.3 26.3 0.2 9.3 19.2 5.2 5.2 20.0 26.1 0.3 13.4 9.8 13.1 82.2 34.9 18.2 15.2 11.8 0.2 0.1 0.3 8.6 9.5 3.2 6.0 3.5 6.7 3.3 2.5 12.3 0.4 4.0 4.4 3.3 0.2 2.4 1.6 1.8 3.5 2.7 3.2 5.5 1.9 7.0 9.0 4.3 5.7 10.0 4.9 12.3 10.3 15.1 3.5 16.5 4.5 160.9 214.7 94.5 41.4 11.7 24.2 16.0 19.5 47.3 37.0 14.2 13.8 71.8 32.9 73.2 22.0 2.1 84.7 27.5 58.9 13.7 30.5 10.1 49.6 43.7 158.6 21.6 32.8 55.2 22.5 49.8 144.8 54.6 64.7 38.7 34.9 157.1 27.6 35.4 101.0 133.8 19.2 24.4 121.1 40.2 23.2 103.2 52.5 24.9 77.8 71.7 10.3 15.5 5.5 20.9 49.4 22.3 120.0 10.6 63.3 20.2 24.8 51.1 3.0 98.6 95.9 83.5 3.1 2.3 33.0 17.2 52.5 51.3 127.9 26.3 30.9 PHF19 "DKFZP727G051, MTF2L1, PCL3, TDRD19B" ENSG00000119403 "PHD finger protein 19" Q5T6S3 9 120855651-120894896 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 43.9;Plasma cells: 46.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 58.2;non-classical monocyte: 79.7;T-reg: 31.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 508.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.05e-1)" "unprognostic (2.25e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.60e-4)" "unprognostic (2.78e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (5.16e-5)" "unprognostic (2.74e-3)" "unprognostic (5.18e-2)" "unprognostic (2.84e-1)" "unprognostic (8.29e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (2.55e-2)" "unprognostic (2.67e-1)" "unprognostic (1.87e-3)" "unprognostic (2.01e-2)" 16.5 15.6 24.3 24.0 29.1 57.5 13.7 23.8 26.2 28.3 15.9 25.6 7.5 18.9 10.4 25.7 27.1 12.5 15.7 24.3 23.3 9.9 6.0 19.6 40.4 28.6 27.6 29.4 5.2 5.1 29.9 12.8 26.0 23.7 17.8 21.0 9.7 17.2 9.4 10.9 21.2 24.2 24.0 28.0 19.5 11.7 26.4 39.0 11.1 11.7 45.9 28.4 23.7 37.1 48.6 165.8 34.3 78.1 27.9 57.0 6.1 52.1 70.1 227.7 165.0 92.3 105.4 102.1 32.7 69.7 71.8 112.8 104.2 108.0 107.0 105.1 44.3 105.6 215.2 61.0 15.8 156.4 48.2 32.5 17.9 100.2 105.5 61.5 151.3 96.9 290.3 272.9 124.2 117.7 105.2 151.9 37.8 147.4 275.2 79.7 38.8 279.1 70.5 15.9 110.0 50.4 97.4 1.6 51.6 31.5 92.4 64.3 55.9 48.1 59.4 47.5 111.1 142.5 508.4 167.9 30.6 94.0 134.7 1.0 13.7 2.1 5.6 58.2 4.5 5.8 12.2 4.6 14.1 3.7 6.1 4.8 2.0 4.6 79.7 5.0 31.4 9.8 24.3 29.1 23.8 26.2 24.3 23.3 28.6 27.6 26.0 24.0 26.4 37.1 4.0 0.0 7.9 5.2 18.0 9.3 9.4 3.2 6.2 7.4 5.0 9.9 5.2 1.5 6.0 0.0 10.4 0.9 18.0 7.5 1.9 2.2 2.5 1.1 9.1 8.4 1.2 18.1 2.0 2.2 2.6 14.9 3.1 2.0 26.0 8.1 6.1 1.1 28.6 0.0 1.9 7.7 0.0 18.6 43.9 3.5 7.8 23.1 16.0 2.8 9.5 18.7 9.2 4.5 9.5 3.0 4.6 15.4 46.1 6.2 1.8 1.5 0.2 23.4 0.0 7.0 12.9 8.2 15.1 15.9 6.8 1.4 25.0 12.7 13.3 8.4 PHGR1 ENSG00000233041 "Proline, histidine and glycine rich 1" C9JFL3 15 40351033-40356434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 2541.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 19911.4;Intestinal goblet cells: 8220.0;Paneth cells: 9497.7;Proximal enterocytes: 51149.4" "Group enriched" "Detected in many" 16 "colorectal cancer: 248.3;stomach cancer: 94.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "OE19: 833.5" HPA068787 Enhanced Approved Vesicles NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA068787: AB_2686035" "prognostic favorable (2.05e-4)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (1.18e-1)" "unprognostic (2.80e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-2)" 3.7 0.4 0.1 88.8 0.2 0.2 11.1 0.3 0.1 0.8 0.0 2541.0 881.0 1.2 0.0 2.0 3.5 0.3 0.3 0.1 0.1 1.9 1.0 0.2 1.2 0.1 0.1 0.5 1.9 0.0 0.5 0.0 0.1 2.5 370.7 0.0 0.3 3.0 0.4 3.7 2320.2 17.3 0.1 0.4 177.1 0.3 0.1 0.0 0.4 0.0 0.0 5.6 1.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.0 0.1 833.5 0.3 0.1 0.0 10.8 0.0 1.5 61.5 7.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 46.0 0.0 0.2 0.3 0.0 0.0 40.2 38.0 0.0 117.2 0.0 0.0 0.0 0.0 0.1 19911.4 0.0 2.5 0.1 0.0 0.0 0.2 1938.2 0.0 0.0 0.2 0.0 0.5 884.8 0.1 213.9 0.0 0.0 0.6 0.0 0.0 0.0 8220.0 20.3 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 9497.7 0.0 2.1 1.1 51149.4 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 32.6 0.0 4881.6 1.0 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748293-30761176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 130.1" "Group enriched" "Detected in many" 5 "Early spermatids: 397.0;Late spermatids: 1576.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favorable (7.90e-4)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favorable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favorable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 9.0 15.8 17.5 11.5 16.9 30.0 9.9 17.1 18.7 10.0 15.9 12.9 11.0 10.1 9.5 10.2 11.7 8.2 12.1 18.9 16.4 14.7 19.1 10.0 12.5 17.7 17.2 8.3 9.7 18.9 15.9 7.8 18.8 14.7 12.0 8.9 11.5 12.0 13.2 14.6 12.0 9.9 16.0 12.9 13.8 130.1 17.5 11.6 13.6 8.8 12.7 10.1 9.2 16.2 24.7 16.3 13.1 16.2 11.8 9.4 29.8 17.2 24.6 22.1 25.1 13.5 12.6 21.0 19.3 17.1 11.5 24.0 13.5 21.5 17.6 11.4 38.2 11.9 28.8 38.7 18.1 18.1 16.9 12.9 11.2 21.4 9.9 10.7 22.8 15.3 16.1 11.7 16.3 55.5 22.3 27.1 18.0 17.6 18.0 29.4 20.0 28.2 25.7 27.2 17.5 11.9 13.5 38.1 16.6 11.8 30.1 15.5 13.6 14.4 15.1 17.2 16.0 24.1 14.4 14.8 27.3 35.2 11.4 44.0 55.8 114.9 37.8 56.5 30.9 21.1 27.1 38.8 52.0 21.5 24.2 27.7 44.7 63.8 42.3 46.1 43.3 49.0 17.5 16.9 17.1 18.7 18.9 16.4 17.7 17.2 18.8 16.0 17.5 16.2 10.4 12.8 21.7 13.7 18.5 21.0 15.2 28.7 22.8 8.8 21.8 17.1 15.9 10.0 32.0 18.4 10.4 29.6 32.2 32.1 27.4 11.9 397.0 35.8 13.0 10.0 16.3 20.2 14.7 24.4 41.5 11.8 44.4 38.8 13.3 16.1 10.4 24.1 28.2 20.2 14.5 21.4 26.4 19.1 27.2 1576.6 17.4 26.4 12.4 11.2 40.3 13.7 39.1 9.0 8.1 19.6 18.5 23.3 20.5 31.5 27.8 47.3 33.0 9.9 0.0 8.9 14.8 180.5 22.9 20.5 23.0 75.5 25.9 20.8 27.0 16.9 PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76031776 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 159.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1438.7;Basal squamous epithelial cells: 582.8;Urothelial cells: 760.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "monocytes: 1.1;T-cells: 1.6" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 296.3;RPTEC TERT1: 233.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" Nucleoplasm "CAB016160: AB_628117, HPA019000: AB_1855309, HPA063520: AB_2685028" "unprognostic (9.09e-2)" "unprognostic (2.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.51e-3)" "unprognostic (2.33e-1)" "unprognostic (2.60e-3)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-1)" "unprognostic (4.55e-3)" 21.3 31.0 9.9 17.3 10.1 21.8 28.1 8.9 11.0 23.1 6.2 8.9 6.5 13.4 4.4 59.8 7.8 39.3 20.6 10.3 11.3 14.8 67.6 27.1 5.9 10.8 16.9 19.2 17.9 5.3 8.2 14.3 11.3 8.9 10.2 13.8 159.1 8.2 5.8 11.5 8.6 14.8 9.6 19.5 22.5 3.1 11.5 7.4 27.2 1.5 7.5 60.9 33.7 11.3 60.9 71.5 54.9 30.4 25.0 51.6 3.9 50.5 134.7 22.4 30.8 39.7 72.2 0.3 14.8 21.2 73.8 30.7 1.5 84.2 47.9 9.3 1.2 1.5 3.8 68.2 36.3 1.4 15.1 16.2 60.6 93.2 182.6 296.3 54.4 0.1 5.0 1.7 115.8 7.8 0.2 7.9 20.1 36.3 108.7 0.2 14.3 1.8 233.7 135.1 4.0 10.4 8.8 0.8 169.5 67.8 35.5 0.7 50.8 75.8 7.2 89.3 50.4 0.8 0.3 0.2 127.9 0.8 96.7 0.2 0.0 0.0 0.9 0.1 1.5 0.0 0.9 1.0 0.0 0.0 0.1 0.2 0.2 0.0 1.1 0.0 1.6 0.2 9.9 10.1 8.9 11.0 10.3 11.3 10.8 16.9 11.3 9.6 11.5 11.3 98.5 12.8 12.4 7.2 13.0 195.3 1438.7 249.6 582.8 5.2 136.2 140.3 34.8 11.5 44.4 31.3 2.1 4.7 42.9 11.6 84.1 74.8 2.2 11.5 111.2 162.5 117.7 0.0 7.8 43.1 11.5 203.2 55.0 20.4 79.5 7.1 21.4 127.8 94.7 1.7 14.6 41.0 384.5 14.0 123.4 2.1 9.3 110.8 286.4 8.4 24.0 97.8 0.0 142.2 2.7 208.4 27.7 15.4 19.0 116.1 0.2 39.3 12.4 5.2 269.5 59.8 276.3 0.7 3.2 66.3 75.6 7.4 132.8 20.7 18.0 760.3 PHLDA3 TIH1 ENSG00000174307 "Pleckstrin homology like domain family A member 3" Q9Y5J5 1 201464278-201469237 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 269.3;Prostatic glandular cells: 188.7;Urothelial cells: 556.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 284.8;WM-115: 164.3" "Low region specificity" "Detected in all" HPA027601 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "HPA027601: AB_10601389" "unprognostic (1.51e-1)" "unprognostic (7.48e-2)" "unprognostic (5.65e-2)" "prognostic favorable (1.77e-4)" "unprognostic (8.55e-3)" "unprognostic (4.34e-3)" "unprognostic (5.55e-3)" "unprognostic (1.42e-1)" "unprognostic (2.16e-3)" "unprognostic (8.65e-2)" "unprognostic (8.78e-2)" "unprognostic (7.65e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (9.32e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (7.45e-2)" 155.6 30.0 34.9 8.4 50.6 0.3 119.3 51.2 41.9 56.8 21.3 139.4 4.1 52.9 11.6 89.4 40.8 15.3 40.9 31.7 39.4 18.2 8.1 41.6 2.5 73.4 50.3 23.5 23.4 10.7 28.4 8.9 51.3 64.8 5.5 3.0 39.3 26.8 75.9 68.3 29.0 17.8 45.2 10.4 35.1 8.9 52.1 10.1 31.5 11.6 4.9 75.5 68.4 69.2 52.4 60.8 11.1 33.5 50.6 47.7 284.8 75.6 57.3 18.2 21.0 4.0 39.5 0.1 3.1 37.6 15.7 90.0 1.0 61.0 3.6 0.0 22.4 0.0 26.2 47.6 57.4 0.0 1.0 66.7 90.6 29.4 25.8 53.5 26.3 4.5 0.0 0.1 36.7 37.5 8.0 0.8 19.1 0.0 3.8 2.5 51.9 0.0 16.9 115.1 0.7 11.7 26.5 0.8 62.7 42.5 25.0 3.6 39.4 42.2 69.6 36.1 16.2 1.4 0.2 0.1 102.4 0.1 164.3 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.2 0.0 0.1 0.6 0.0 34.9 50.6 51.2 41.9 31.7 39.4 73.4 50.3 51.3 45.2 52.1 69.2 83.3 9.6 9.1 8.8 0.9 78.1 269.3 48.8 93.9 5.2 29.8 42.4 6.2 2.8 30.7 49.7 0.0 84.9 1.8 2.2 11.7 42.0 36.8 42.7 15.2 22.2 5.3 2.7 5.7 18.9 24.4 43.3 7.1 31.8 0.0 11.2 10.4 1.4 18.1 0.0 8.3 2.1 10.2 0.6 28.5 136.5 26.8 7.9 32.0 1.0 18.2 105.4 1.0 4.5 37.1 71.4 2.9 41.8 2.1 188.7 1.2 8.5 22.3 5.2 0.0 38.0 55.8 0.8 4.0 92.1 102.0 37.5 5.7 46.5 3.6 556.5 PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 87.2;Late spermatids: 87.7;Oligodendrocytes: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.2;ASC TERT1: 105.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "Plasma membrane" "HPA037959: AB_10673651, HPA038448: AB_10697390" "unprognostic (7.81e-2)" "unprognostic (8.32e-3)" "unprognostic (1.13e-1)" "unprognostic (9.36e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.37e-3)" "unprognostic (1.22e-1)" "unprognostic (3.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.36e-6)" "unprognostic (7.09e-2)" "unprognostic (2.42e-2)" "unprognostic (3.69e-2)" "unprognostic (1.44e-1)" 52.6 8.1 39.2 11.5 79.7 0.5 38.9 42.5 66.0 39.1 3.8 23.8 9.2 38.4 2.6 9.1 30.2 21.6 33.0 42.3 49.2 15.8 3.2 26.8 4.6 64.3 64.6 31.9 22.2 4.5 8.8 24.6 56.0 16.7 6.4 1.6 11.1 15.8 13.3 15.1 15.3 18.6 33.4 12.5 14.3 12.0 75.3 3.1 20.3 13.6 2.3 21.9 22.9 133.7 4.8 7.5 28.9 14.2 105.2 105.9 10.1 21.9 26.6 12.7 7.4 11.2 31.8 0.0 40.2 44.3 17.2 18.6 6.6 44.8 2.0 0.7 4.2 8.6 5.7 5.5 27.2 0.0 15.8 55.8 9.6 17.8 12.5 28.3 36.6 0.7 7.5 0.3 16.7 3.4 0.1 0.5 10.2 0.4 3.8 1.1 7.5 0.7 12.5 6.8 6.5 14.5 55.8 4.7 15.6 11.3 20.1 2.7 45.4 25.9 22.9 13.2 18.3 0.2 0.0 0.1 7.5 1.5 29.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 39.2 79.7 42.5 66.0 42.3 49.2 64.3 64.6 56.0 33.4 75.3 133.7 34.4 6.4 13.7 53.2 1.6 18.4 9.2 13.7 14.2 4.0 7.2 19.6 5.6 1.5 6.3 31.3 0.0 1.0 2.5 34.2 0.0 9.4 78.3 11.6 87.2 32.1 8.4 0.0 4.1 4.4 1.5 54.9 11.7 8.6 1.3 25.6 26.4 0.9 5.9 3.3 8.3 20.4 0.0 2.5 34.4 87.7 67.1 8.2 12.4 23.4 2.2 7.6 0.0 67.3 244.5 24.3 29.8 44.4 0.7 4.2 10.7 7.8 0.5 2.3 39.5 42.9 53.8 21.9 10.1 1.9 9.1 1.5 5.4 11.0 16.8 2.4 PHLDB2 "FLJ21791, LL5b, LL5beta" ENSG00000144824 "Pleckstrin homology like domain family B member 2" Q86SQ0 3 111732497-111976517 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 249.9;Basal prostatic cells: 189.9;Suprabasal keratinocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 103.8;HaCaT: 105.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035146, HPA035147" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA035146: AB_10600927, HPA035147: AB_2674492" "unprognostic (2.83e-2)" "unprognostic (4.93e-3)" "unprognostic (2.15e-2)" "unprognostic (8.01e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (5.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-2)" "unprognostic (2.00e-2)" "unprognostic (3.53e-1)" "prognostic favorable (7.03e-8)" "unprognostic (3.24e-3)" "unprognostic (3.47e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" 25.6 7.2 2.2 15.7 2.3 1.5 11.3 0.9 4.0 10.6 10.3 29.0 6.0 20.4 7.4 11.1 13.3 15.3 42.7 0.9 0.5 31.5 35.6 17.6 5.1 1.2 1.8 8.9 10.0 1.8 5.7 40.8 1.6 16.4 8.6 0.5 10.6 25.7 4.8 7.0 7.7 24.3 1.6 16.5 11.7 2.8 3.9 5.0 6.2 8.7 3.2 26.5 10.5 2.0 103.8 11.2 62.2 0.1 19.8 32.3 25.5 58.3 28.5 37.8 44.5 32.1 7.5 0.0 59.6 22.6 38.2 105.2 0.9 37.5 68.6 1.6 1.5 0.0 26.1 10.6 21.3 0.2 0.3 38.1 21.9 26.1 48.1 42.5 61.8 1.0 0.1 0.4 11.5 0.2 4.2 0.1 25.3 1.0 19.3 9.0 80.1 0.0 22.2 24.5 1.6 4.7 57.6 1.1 5.9 34.1 2.1 0.3 54.4 10.2 85.2 27.4 14.3 5.4 0.2 0.2 10.4 0.1 19.9 0.1 0.0 0.0 2.6 0.0 1.8 0.2 1.8 2.9 0.0 0.4 0.0 1.1 0.2 1.0 0.0 0.5 0.4 0.8 2.2 2.3 0.9 4.0 0.9 0.5 1.2 1.8 1.6 1.6 3.9 2.0 30.9 80.1 7.5 2.6 1.6 249.9 189.9 33.3 33.0 0.2 11.6 9.8 95.8 25.8 16.8 33.1 2.1 27.0 13.0 0.6 23.5 62.6 12.9 3.7 15.3 44.8 10.8 2.7 51.7 20.5 51.5 40.3 14.3 26.2 7.0 1.2 35.3 35.2 3.5 0.0 9.5 3.4 8.2 2.5 20.6 5.3 14.3 2.9 23.2 39.4 1.0 0.1 23.7 4.5 1.8 45.4 0.5 22.6 2.8 60.1 0.0 30.9 6.8 0.3 13.1 21.0 95.9 0.5 3.3 17.7 114.7 66.8 6.7 2.7 1.9 84.0 PHYH "PAHX, PHYH1, RD" ENSG00000107537 "Phytanoyl-CoA 2-hydroxylase" O14832 10 13277796-13302412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 667.8;skeletal muscle: 483.6;tongue: 412.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 258.6;Proximal tubular cells: 414.6" "Cancer enhanced" "Detected in all" "liver cancer: 78.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007598, HPA011796" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA007598: AB_1855334, HPA011796: AB_1855335" "unprognostic (5.78e-2)" "unprognostic (3.83e-1)" "unprognostic (6.98e-2)" "unprognostic (3.62e-2)" "unprognostic (5.52e-2)" "unprognostic (1.61e-3)" "unprognostic (1.16e-1)" "unprognostic (1.95e-2)" "unprognostic (7.09e-2)" "unprognostic (6.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.24e-1)" "prognostic favorable (7.28e-12)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.19e-1)" 57.9 66.5 22.9 9.5 23.7 8.2 32.2 23.5 28.3 28.8 31.7 46.5 58.7 22.1 16.7 22.9 16.7 28.2 126.5 21.7 24.1 191.4 667.8 17.3 7.5 21.6 24.4 36.8 48.2 56.7 20.9 19.3 22.8 22.5 37.2 28.2 33.7 25.4 483.6 17.5 55.8 23.2 22.7 12.8 44.2 15.1 26.0 5.6 56.0 412.7 5.4 27.0 14.8 23.6 17.2 35.2 15.6 22.5 110.7 69.9 12.4 17.2 23.9 19.4 19.1 9.1 30.3 0.9 12.9 29.0 47.0 7.8 20.5 20.2 11.8 41.4 10.7 14.9 9.3 36.6 54.8 2.5 26.8 50.3 28.9 21.0 8.4 22.7 18.7 16.8 8.4 32.2 45.5 16.3 9.2 12.1 14.4 49.4 12.6 15.7 24.1 5.8 40.6 21.9 5.3 16.8 64.8 1.4 32.9 12.5 64.8 44.2 6.4 29.5 10.6 36.4 11.8 36.6 26.3 3.3 38.3 18.9 11.6 16.3 18.7 8.2 8.0 14.2 17.6 11.0 9.9 10.4 15.8 5.6 12.5 12.7 0.8 4.4 11.2 14.4 10.5 12.3 22.9 23.7 23.5 28.3 21.7 24.1 21.6 24.4 22.8 22.7 26.0 23.6 53.6 12.8 19.2 8.5 14.5 11.9 27.6 19.1 6.2 47.0 22.6 24.5 258.6 77.2 19.7 35.0 22.9 137.8 20.5 72.9 144.8 40.6 33.1 18.5 29.0 29.7 31.8 15.2 7.1 19.6 34.3 41.3 41.8 26.8 30.4 28.3 25.0 145.5 55.4 21.9 5.6 57.4 46.8 21.0 22.0 45.4 25.4 25.3 17.8 4.7 10.3 69.3 7.2 2.5 2.4 16.7 46.0 37.6 15.1 11.9 141.9 414.6 19.6 41.8 19.7 30.2 37.5 12.5 1.6 7.3 13.4 83.9 25.2 103.3 46.9 18.1 PHYHD1 MGC16638 ENSG00000175287 "Phytanoyl-CoA dioxygenase domain containing 1" Q5SRE7 9 128920966-128942041 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Muller glia cells: 139.3;Proximal tubular cells: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 13.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 13.0" "Cell line enhanced" "Detected in many" "ASC diff: 46.5;ASC TERT1: 32.7;BEWO: 50.6;HSkMC: 28.3;RPTEC TERT1: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012115 Approved "Nuclear speckles" NA NA 36000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA012115: AB_1859448" "unprognostic (1.18e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.09e-3)" "unprognostic (2.16e-1)" "unprognostic (1.17e-2)" "unprognostic (4.49e-2)" "unprognostic (5.37e-3)" "unprognostic (1.35e-1)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (3.70e-2)" "prognostic favorable (6.38e-10)" "unprognostic (1.10e-2)" "unprognostic (3.09e-1)" "unprognostic (2.14e-1)" "unprognostic (9.83e-3)" 28.2 25.7 41.9 3.2 39.9 8.4 34.6 37.9 40.8 39.8 41.7 24.4 2.3 33.8 38.3 25.6 28.5 13.2 35.1 36.3 46.9 49.9 78.7 23.1 4.5 48.1 51.9 39.1 70.2 15.6 15.5 9.6 46.5 36.8 3.8 41.8 40.0 30.0 29.3 43.7 12.4 15.4 48.1 14.7 33.4 7.2 47.9 6.8 43.0 12.8 4.6 25.9 25.6 48.7 0.2 0.5 0.4 0.8 46.5 32.7 50.6 3.7 0.0 3.4 6.0 1.8 0.5 0.7 0.4 3.0 0.3 0.7 0.4 0.3 2.9 0.5 5.4 0.1 6.7 18.0 15.1 0.8 0.6 28.3 1.0 0.4 0.2 0.2 0.3 0.3 0.3 1.2 24.3 0.4 0.5 0.7 17.0 0.2 0.2 20.5 9.7 0.3 78.9 0.7 1.1 0.4 0.5 0.3 0.3 11.4 4.7 0.6 1.3 0.7 2.1 0.7 0.5 0.4 0.9 20.7 0.3 0.4 0.7 1.3 0.2 0.2 1.3 0.3 0.3 2.8 0.4 0.5 1.7 0.7 1.8 1.9 0.8 2.2 0.4 13.0 0.3 0.5 41.9 39.9 37.9 40.8 36.3 46.9 48.1 51.9 46.5 48.1 47.9 48.7 8.5 32.1 34.3 51.6 3.7 22.0 63.2 26.8 57.5 9.4 40.0 46.9 19.8 10.0 31.0 33.1 29.2 58.8 3.4 0.7 119.3 11.4 0.4 27.0 26.0 9.5 1.2 12.0 1.2 15.8 30.0 34.5 7.7 53.8 0.0 42.8 31.8 82.2 10.7 3.3 0.8 2.4 4.1 3.2 5.5 4.2 68.6 3.1 12.4 5.6 0.1 139.3 4.1 1.0 0.7 14.2 0.5 66.2 2.6 19.3 0.0 161.5 14.6 67.5 52.6 48.1 17.8 0.9 3.9 32.7 24.3 30.9 2.7 44.6 1.4 35.0 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 12.0 25.7 15.5 10.0 15.1 24.1 9.3 15.1 18.9 12.6 13.4 10.7 9.8 12.7 13.0 20.7 9.6 14.0 14.2 15.5 17.8 12.6 15.0 14.2 11.2 20.2 18.8 10.0 8.4 16.6 15.8 18.0 22.0 10.9 8.7 12.9 10.5 10.4 12.7 17.4 10.8 13.0 15.8 14.6 9.4 10.8 17.3 9.8 9.5 13.0 10.6 14.5 12.7 15.2 28.7 21.3 17.2 30.7 36.0 25.8 13.8 28.0 61.5 43.3 45.7 19.4 27.7 10.4 16.2 35.8 31.8 27.1 19.3 55.9 35.8 12.6 16.4 9.3 14.6 17.7 34.5 8.4 12.7 27.3 46.9 45.4 80.1 47.4 22.4 19.9 14.7 16.5 30.4 14.6 18.4 6.4 11.1 14.7 19.8 8.6 17.8 10.3 29.7 26.6 5.8 18.9 23.9 5.9 35.5 24.0 16.4 13.2 25.0 20.6 15.2 24.6 22.1 14.6 18.4 16.9 38.1 5.0 6.8 0.0 1.2 0.0 1.3 0.8 1.0 1.4 0.5 1.1 1.3 0.6 0.4 0.9 0.4 0.7 0.6 0.6 1.2 0.6 15.5 15.1 15.1 18.9 15.5 17.8 20.2 18.8 22.0 15.8 17.3 15.2 4.9 3.2 5.4 9.8 12.0 13.4 4.5 6.5 8.0 14.7 10.7 8.9 10.4 10.0 4.3 5.5 12.5 14.0 12.5 8.6 3.9 4.9 2.4 6.8 15.4 6.9 3.0 8.2 10.9 4.9 6.4 12.0 7.1 7.6 1.3 5.7 3.6 9.9 38.1 11.8 10.9 4.0 6.1 15.0 24.7 2.2 4.4 19.0 10.6 12.2 15.0 8.0 18.6 5.5 6.0 7.2 0.8 9.1 9.4 5.8 9.0 7.3 4.8 15.1 6.6 11.9 8.0 11.0 6.1 6.3 14.3 27.1 9.7 12.4 3.6 7.8 PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 500.3;Oligodendrocytes: 709.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 40000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019053: AB_1855361, HPA019061: AB_1855362" "unprognostic (9.27e-3)" "unprognostic (7.29e-2)" "unprognostic (3.51e-1)" "unprognostic (6.83e-2)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (5.36e-3)" "unprognostic (9.02e-3)" "unprognostic (9.80e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.31e-1)" "prognostic favorable (2.02e-6)" "unprognostic (1.26e-2)" "unprognostic (5.21e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" 183.5 62.5 97.1 120.4 162.1 111.4 111.5 119.3 118.7 86.4 43.8 86.3 106.3 79.3 52.4 109.1 66.1 127.0 87.9 91.7 110.8 168.5 147.0 99.4 82.7 125.2 130.7 94.4 80.6 120.6 36.5 157.2 131.6 73.1 83.1 71.5 62.3 93.6 75.8 74.2 115.5 135.3 106.0 126.5 73.0 64.9 120.7 93.1 75.7 101.9 96.7 139.5 73.5 194.7 167.0 78.4 121.1 85.9 185.5 188.8 228.5 211.7 274.7 164.4 143.0 310.7 222.4 126.0 210.8 342.6 171.1 134.6 129.4 154.2 232.8 38.6 45.0 364.9 101.5 98.9 185.6 87.2 158.3 166.6 161.7 308.7 253.3 275.1 178.7 85.9 239.1 103.0 305.2 98.2 103.9 76.8 66.9 269.0 42.7 69.8 182.2 91.1 312.5 139.2 72.9 58.7 258.4 85.4 68.7 156.5 115.6 67.0 196.9 298.6 104.1 355.0 170.2 36.7 107.1 118.4 70.8 64.6 206.6 6.4 13.5 7.5 5.7 11.7 4.9 3.1 4.2 8.0 11.4 2.1 4.2 4.0 40.6 7.1 12.5 3.9 6.4 5.3 97.1 162.1 119.3 118.7 91.7 110.8 125.2 130.7 131.6 106.0 120.7 194.7 147.1 35.3 58.9 134.5 33.3 116.0 44.4 33.0 30.1 20.8 34.8 28.6 46.4 42.9 34.3 71.7 12.5 42.9 43.9 64.2 31.3 57.7 59.3 32.3 32.8 98.7 25.1 88.8 144.7 37.6 127.1 44.6 34.1 50.9 48.2 23.2 71.4 52.3 85.0 40.4 140.7 30.1 30.5 142.8 229.2 95.4 35.8 127.4 60.5 500.3 92.1 22.6 32.0 188.0 709.3 90.2 55.3 43.6 39.1 49.5 71.4 84.0 41.0 16.3 78.9 36.4 92.7 17.3 14.1 34.4 96.5 41.3 38.9 23.6 30.6 77.7 PICK1 "dJ1039K5, MGC15204, PRKCABP" ENSG00000100151 "Protein interacting with PRKCA 1" Q9NRD5 22 38056311-38075701 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.1;Late spermatids: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000819, HPA072674" Approved Supported Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA000819: , HPA072674: AB_2686547" "unprognostic (1.97e-2)" "unprognostic (4.61e-3)" "unprognostic (7.79e-2)" "unprognostic (9.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.81e-1)" "unprognostic (6.04e-2)" "unprognostic (1.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-3)" "unprognostic (1.20e-1)" "unprognostic (8.56e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.36e-1)" "unprognostic (2.74e-1)" "unprognostic (4.61e-3)" 8.8 14.9 12.4 4.8 15.2 5.4 13.5 12.8 20.3 9.9 12.9 11.9 10.1 11.7 13.8 15.9 16.3 8.9 18.2 14.5 13.5 15.1 17.5 10.8 5.4 14.5 13.6 15.4 18.5 29.3 28.8 6.7 16.7 25.6 12.2 5.9 18.6 12.6 26.3 16.9 11.3 11.3 11.6 10.1 16.2 27.4 15.6 5.9 14.6 16.2 8.2 9.3 12.0 23.0 19.5 13.7 7.6 10.0 5.3 4.1 11.3 10.7 12.8 22.5 22.7 14.6 12.0 8.6 11.6 13.0 17.0 20.8 21.0 43.2 19.3 5.3 33.6 3.1 16.8 17.1 19.3 10.1 20.4 13.3 24.9 14.8 21.9 22.8 8.8 11.1 6.4 6.2 4.7 12.4 6.0 0.9 12.1 44.3 14.9 5.1 0.3 7.8 25.8 31.1 31.5 16.0 12.0 28.8 11.1 11.1 16.8 7.3 2.4 6.4 12.0 8.6 6.4 13.9 3.4 2.7 13.8 3.4 9.4 0.0 0.9 0.0 0.5 0.4 0.2 0.3 0.5 1.0 1.6 1.1 1.0 0.5 0.6 0.4 0.5 0.3 0.7 0.6 12.4 15.2 12.8 20.3 14.5 13.5 14.5 13.6 16.7 11.6 15.6 23.0 8.1 9.6 10.6 11.1 8.1 8.0 14.2 15.6 12.0 12.7 18.7 16.1 10.2 11.5 12.1 7.3 8.4 26.1 6.0 25.4 11.7 18.8 116.1 15.4 3.6 7.8 10.3 1.7 26.8 15.7 14.8 6.8 29.6 17.3 8.9 36.3 5.7 9.7 15.1 20.2 19.4 20.1 18.3 31.5 13.3 85.5 11.1 16.3 7.2 6.5 16.0 13.6 8.2 8.5 29.0 21.4 18.5 17.0 5.8 22.1 18.3 16.0 12.8 12.5 13.1 6.0 9.5 17.2 6.7 12.0 9.7 38.4 6.8 15.5 18.5 14.7 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 58.3" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BJ hTERT+ SV40 Large T+: 16.9;BJ hTERT+ SV40 Large T+ RasG12V: 23.1;HeLa: 38.1;U-266/70: 23.0;U-698: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" 1.2 0.5 7.3 1.3 20.2 0.4 1.7 14.7 14.4 1.0 0.1 3.9 0.3 0.6 1.6 5.1 1.1 5.3 0.3 7.9 8.7 1.1 4.1 6.6 0.9 18.2 14.4 0.7 1.8 0.5 0.9 0.0 18.2 3.0 1.4 0.1 0.3 2.9 0.1 1.1 1.1 2.1 8.5 2.7 1.6 1.2 16.8 0.8 1.5 0.2 0.6 5.3 0.7 58.3 0.0 1.8 15.1 0.0 0.0 0.0 0.0 0.8 4.4 16.9 23.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 10.6 0.0 0.5 0.0 38.1 8.8 5.2 0.0 0.1 0.1 0.3 4.3 1.2 0.1 5.2 0.6 0.0 0.3 2.7 0.0 0.3 0.0 4.5 6.7 0.0 0.0 0.0 7.0 0.0 5.3 12.7 0.0 0.1 0.0 0.8 6.7 0.0 4.5 0.0 0.0 5.8 0.3 0.9 23.0 0.2 16.2 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 20.2 14.7 14.4 7.9 8.7 18.2 14.4 18.2 8.5 16.8 58.3 3.3 0.0 5.3 2.0 0.0 0.8 0.3 0.0 0.0 0.0 2.3 0.8 1.6 10.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 31.7 0.2 0.2 9.9 0.0 0.0 2.5 0.2 0.0 11.2 2.6 0.0 5.1 0.1 17.2 5.9 1.0 0.0 37.0 0.0 0.0 3.2 0.8 11.9 0.0 0.6 0.0 9.4 0.0 0.0 0.0 2.0 399.6 0.1 0.0 0.0 0.4 0.1 0.0 0.1 7.3 0.0 6.6 0.9 4.5 0.3 1.4 0.2 0.9 0.4 0.6 32.9 0.0 0.1 PIFO "C1orf88, FLJ23853, pitchfork" ENSG00000173947 "Primary cilia formation" Q8TCI5 1 111346600-111353013 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "fallopian tube: 174.2" "Group enriched" "Detected in many" 4 "Early spermatids: 430.6;Endometrial ciliated cells: 495.3;Late spermatids: 458.1;Respiratory ciliated cells: 990.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 3.4;RPTEC TERT1: 4.7;RT4: 5.9;SuSa: 7.9;T-47d: 3.8;U-87 MG: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.18e-3)" "unprognostic (3.23e-2)" "unprognostic (7.33e-2)" "unprognostic (3.03e-3)" "unprognostic (6.00e-2)" "unprognostic (7.43e-4)" "unprognostic (8.78e-7)" "unprognostic (6.43e-3)" "unprognostic (7.28e-2)" "unprognostic (9.07e-3)" "prognostic favorable (2.48e-4)" "unprognostic (3.32e-2)" "prognostic favorable (1.44e-4)" "unprognostic (6.03e-3)" "unprognostic (4.73e-2)" "unprognostic (6.37e-2)" "unprognostic (6.83e-2)" 1.0 2.8 8.6 0.7 9.1 0.1 5.7 8.2 9.2 4.3 36.5 5.1 0.6 7.4 12.5 3.5 174.2 3.5 9.3 8.5 10.8 8.3 0.0 12.9 0.3 14.3 15.0 3.3 6.4 15.1 9.8 2.9 13.7 12.2 1.1 5.1 3.1 6.0 0.1 1.4 1.1 4.7 12.2 0.4 4.4 24.8 10.8 1.7 15.0 0.9 0.6 5.4 0.8 14.0 0.0 0.0 0.5 0.6 0.6 0.7 1.0 0.0 1.2 0.2 0.0 0.8 1.1 0.0 0.2 0.0 1.1 0.0 0.8 0.2 0.0 1.4 0.2 0.0 0.1 0.9 0.4 0.0 0.0 0.4 3.2 0.0 0.0 3.4 0.0 0.2 0.2 0.1 2.0 0.3 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 4.7 5.9 2.2 0.2 0.0 0.1 0.1 7.9 3.8 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.4 3.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.4 0.2 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 9.1 8.2 9.2 8.5 10.8 14.3 15.0 13.7 12.2 10.8 14.0 0.3 3.2 18.5 3.3 0.5 4.2 9.1 71.5 1.8 0.7 6.0 12.6 17.3 0.0 83.2 5.5 4.2 11.6 0.1 0.0 21.5 13.0 430.6 495.3 5.8 1.6 3.0 0.0 0.5 2.0 4.4 3.7 1.5 9.0 0.0 3.8 0.7 0.1 1.2 0.0 1.4 0.0 77.3 0.0 0.7 458.1 5.9 1.5 8.8 0.0 0.0 11.8 0.0 0.5 0.6 1.2 0.0 3.4 0.4 6.2 0.0 36.3 990.5 5.4 6.6 4.6 22.8 127.1 10.5 0.5 2.8 7.0 1.0 8.4 0.1 4.3 PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584109 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 78.9;Late spermatids: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: AB_10796221, HPA039828: AB_10795158, HPA061414: AB_2684508" "unprognostic (1.23e-2)" "unprognostic (6.12e-3)" "unprognostic (2.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.09e-2)" "unprognostic (2.42e-1)" "unprognostic (9.58e-2)" "unprognostic (8.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (8.98e-2)" "prognostic favorable (2.53e-6)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" 13.3 23.9 7.1 3.8 8.0 30.4 15.0 2.0 12.0 15.4 8.6 16.2 7.5 18.3 1.4 13.2 16.5 2.8 13.3 9.6 5.2 30.7 19.0 17.9 2.5 6.6 9.7 15.6 21.9 9.4 25.4 3.3 6.5 19.4 1.1 1.2 19.3 5.8 18.4 15.7 12.6 1.6 3.5 15.0 17.0 28.1 6.0 2.7 31.1 1.7 1.2 15.8 12.1 4.3 14.2 21.9 7.3 10.3 4.6 2.7 13.9 14.7 5.6 6.3 6.6 14.6 12.9 7.6 18.6 3.3 5.5 22.2 3.3 6.4 1.3 21.9 30.4 11.4 23.8 10.8 8.9 10.1 10.2 5.2 9.8 10.2 2.0 4.0 6.1 13.7 26.1 4.1 2.1 20.7 18.3 11.4 10.0 3.0 21.9 36.6 6.4 17.7 5.6 5.6 13.2 21.4 16.8 7.6 10.8 2.3 17.3 6.9 14.5 10.4 13.7 11.7 10.4 15.8 5.0 6.0 4.8 5.4 10.4 0.9 2.8 1.6 2.8 3.1 2.4 2.3 2.3 2.6 2.7 2.5 2.5 1.6 3.0 3.3 3.7 5.6 2.4 2.6 7.1 8.0 2.0 12.0 9.6 5.2 6.6 9.7 6.5 3.5 6.0 4.3 9.7 16.0 20.3 14.0 6.9 4.8 6.6 8.4 5.2 12.1 15.8 11.0 8.4 4.3 10.6 40.5 4.2 10.5 8.8 31.5 3.9 19.3 33.6 21.0 7.8 9.0 20.3 78.9 19.3 17.4 8.4 9.4 16.3 11.4 8.2 19.7 6.4 16.4 9.5 10.1 13.8 13.0 8.2 9.1 4.4 61.4 7.5 8.2 16.0 3.7 7.7 14.6 10.3 7.5 6.6 14.1 11.6 7.2 9.1 6.9 7.6 12.4 23.3 13.7 0.0 7.7 9.9 30.1 13.6 6.2 4.8 5.9 7.8 11.1 16.9 5.0 PIGT ENSG00000124155 "Phosphatidylinositol glycan anchor biosynthesis class T" Q969N2 20 45416084-45456934 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.06e-2)" "unprognostic (4.60e-3)" "unprognostic (7.63e-2)" "unprognostic (6.00e-2)" "unprognostic (6.18e-3)" "unprognostic (6.68e-2)" "unprognostic (7.34e-3)" "unprognostic (1.17e-1)" "unprognostic (2.70e-2)" "unprognostic (3.32e-1)" "prognostic favorable (2.51e-4)" "unprognostic (5.48e-2)" "unprognostic (7.60e-2)" "unprognostic (9.21e-2)" "unprognostic (5.66e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-2)" 57.4 51.9 30.7 39.4 38.9 70.8 52.7 41.2 37.5 65.5 44.6 75.8 49.9 69.6 89.5 37.7 61.2 48.3 113.5 29.9 37.2 47.1 48.9 45.3 26.6 41.0 38.1 46.1 65.0 105.4 48.9 48.5 38.9 39.5 77.2 13.0 48.2 55.6 61.2 46.0 54.3 69.7 37.6 36.5 62.1 38.1 38.8 25.8 57.0 51.8 27.4 57.0 42.8 47.6 79.0 95.3 35.8 138.7 218.0 152.9 68.5 90.4 172.8 126.8 99.7 179.9 123.6 47.1 122.0 142.9 108.4 152.4 43.6 124.8 67.8 25.2 53.5 49.0 80.8 100.9 99.9 93.5 203.1 117.3 117.0 99.9 108.6 179.4 109.3 39.2 65.0 163.8 107.4 165.3 44.8 74.7 29.4 227.5 162.1 38.0 107.6 168.0 102.5 51.1 60.2 77.0 177.7 173.2 88.7 61.4 150.6 169.8 96.5 301.4 138.1 57.1 128.8 93.9 144.0 30.0 190.7 74.7 140.9 58.9 77.9 66.3 57.4 83.2 43.6 27.2 41.0 53.8 92.2 28.1 35.7 41.8 30.7 57.6 79.2 71.4 61.6 83.1 30.7 38.9 41.2 37.5 29.9 37.2 41.0 38.1 38.9 37.6 38.8 47.6 41.9 41.7 29.5 9.1 43.9 30.0 46.4 86.8 13.6 21.0 43.7 31.4 169.2 41.5 63.7 44.1 14.6 62.1 58.9 106.1 13.7 107.5 31.8 45.2 32.3 46.0 65.5 24.2 7.6 114.5 73.9 94.2 44.9 59.2 33.6 58.5 39.7 41.5 76.8 38.7 9.8 145.3 85.5 49.6 42.6 81.4 60.6 44.3 88.9 4.7 39.8 25.8 37.0 6.0 27.1 79.5 61.8 56.1 69.2 40.7 103.8 26.1 46.2 15.6 65.7 39.4 47.2 88.4 96.9 23.5 27.8 52.1 43.4 47.9 111.6 57.7 PIK3R5 "p101, P101-PI3K" ENSG00000141506 "Phosphoinositide-3-kinase regulatory subunit 5" Q8WYR1 17 8878911-8965712 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 87.4" "Cell type enhanced" "Detected in some" "dendritic cells: 29.9;Kupffer cells: 35.7;Langerhans cells: 40.5;Macrophages: 36.8;Microglial cells: 79.6;NK-cells: 32.0;Plasma cells: 24.7;T-cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 39.2;HMC-1: 5.7;JURKAT: 13.7;U-937: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044505, HPA052247, HPA052412" Uncertain Supported "Centriolar satellite,Cytosol" No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Centriolar satellite" "HPA044505: AB_2678964, HPA052247: AB_2681772, HPA052412: AB_2681823" "unprognostic (2.81e-1)" "unprognostic (1.31e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (9.89e-3)" "unprognostic (1.42e-1)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (7.95e-2)" "unprognostic (1.33e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" "unprognostic (6.89e-2)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.24e-1)" 6.5 3.6 1.4 19.7 1.3 87.4 2.7 1.3 7.5 2.1 1.6 3.3 3.3 1.4 0.8 2.5 3.0 6.6 1.8 1.3 1.7 1.4 2.9 14.1 13.7 4.0 2.7 0.8 1.3 0.8 0.8 3.1 3.6 1.5 2.6 0.0 2.1 1.0 0.7 1.5 9.5 3.9 2.8 22.4 3.6 2.2 6.8 12.3 1.7 0.9 8.9 6.5 1.4 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.4 1.5 0.0 0.0 0.0 0.5 5.7 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.3 1.5 2.5 0.6 0.0 0.0 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 9.5 16.1 5.7 18.1 14.3 11.8 4.3 10.1 15.6 11.5 5.7 7.5 12.0 34.4 8.6 19.0 9.0 13.2 16.2 1.4 1.3 1.3 7.5 1.3 1.7 4.0 2.7 3.6 2.8 6.8 5.4 0.2 0.0 6.1 0.7 11.7 1.0 0.0 0.0 0.0 0.0 0.2 0.3 2.1 1.5 0.0 0.0 0.0 0.1 29.9 0.0 0.0 0.1 4.5 0.1 0.1 0.7 0.0 4.0 0.3 0.0 0.3 0.5 1.5 0.1 5.1 0.0 1.4 0.4 18.3 0.0 0.5 0.0 0.0 35.7 40.5 12.2 0.3 36.8 1.8 79.6 19.8 0.0 32.0 1.0 0.3 0.0 0.0 0.0 24.7 0.1 0.0 0.2 0.0 0.0 0.0 0.4 1.4 0.6 0.4 0.1 0.9 0.4 25.7 0.0 0.0 0.0 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 102.3;intestine: 87.6;lymphoid tissue: 163.9" "Cell type enriched" "Detected in many" 4 "Plasma cells: 738.8" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "HDLM-2: 567.6;Karpas-707: 675.0;RPMI-8226: 703.9;U-266/70: 1218.7;U-266/84: 1160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favorable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 7.9 7.1 10.9 85.4 11.4 102.3 8.8 9.6 12.3 6.1 11.1 40.8 87.6 5.1 10.1 8.2 11.9 16.7 5.2 15.4 12.4 9.8 10.4 23.5 114.3 9.7 10.7 10.3 4.7 3.8 10.1 4.9 11.7 7.4 50.9 5.6 36.4 7.3 2.5 6.3 46.4 6.9 10.3 163.9 45.1 10.1 13.5 45.5 10.1 2.7 104.7 45.6 6.4 8.8 17.5 14.8 8.0 15.4 2.8 2.0 11.7 10.5 13.1 14.8 13.2 13.3 12.9 74.5 4.8 5.3 5.6 10.6 25.1 10.0 14.1 567.6 19.6 90.8 15.0 13.9 6.2 21.7 58.7 5.9 8.4 15.3 9.2 12.1 5.5 9.8 97.8 675.0 8.4 12.6 8.4 45.2 165.2 6.1 22.7 9.9 5.4 703.9 14.9 2.6 5.4 7.8 11.5 8.0 8.3 36.9 19.3 29.8 3.6 3.5 2.5 3.1 10.6 1218.7 1160.5 144.1 14.0 19.0 3.7 279.1 8.2 77.7 60.4 9.7 102.3 124.8 165.9 85.6 13.2 73.5 172.4 113.3 195.5 92.7 17.4 15.2 331.9 79.0 10.9 11.4 9.6 12.3 15.4 12.4 9.7 10.7 11.7 10.3 13.5 8.8 2.9 12.8 36.0 1.0 161.6 20.3 9.0 7.1 45.5 2.6 16.2 4.7 3.5 2.8 9.9 3.7 2.1 5.8 46.8 5.7 3.9 3.3 1.9 15.6 1.0 5.3 13.1 49.9 2.3 3.5 9.1 5.1 10.7 3.9 23.4 1.3 4.2 6.3 7.2 11.8 2.2 7.5 18.3 7.5 123.1 1.8 1.8 19.8 94.3 0.0 99.5 2.2 38.1 0.5 1.0 2.0 3.7 4.1 738.8 4.6 4.1 6.8 16.3 2.1 0.0 3.8 6.2 2.2 1.6 15.7 13.8 2.5 97.1 8.6 11.8 3.4 PIP "GCDFP-15, GCDFP15, GPIP4" ENSG00000159763 "Prolactin induced protein" P12273 7 143132077-143139739 "Plasma proteins, Predicted secreted proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 16791.8" "Group enriched" "Detected in many" 4 "Breast glandular cells: 1117.6;Breast myoepithelial cells: 324.2;Melanocytes: 403.8" "Cancer enriched" "Detected in many" 70 "breast cancer: 672.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 333 "T-47d: 703.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB002661, HPA009177" Enhanced "Secreted in other tissues" NA NA 66000000 "Cluster 37: B-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "CAB002661: , HPA009177: AB_1845459" "unprognostic (2.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-3)" "unprognostic (3.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.14e-1)" "unprognostic (3.49e-2)" "unprognostic (5.55e-1)" 9.1 3.6 0.7 0.2 4.8 0.1 3458.7 2.7 2.7 5.6 0.0 0.5 0.0 0.1 2.7 1.3 4.2 0.1 4.8 0.9 4.6 0.5 2.0 6.4 0.8 8.5 4.4 3.8 21.1 0.4 1.9 2.3 6.8 33.3 0.0 0.0 16791.8 3140.5 1.7 189.7 0.6 0.0 3.5 0.6 0.6 0.7 4.6 0.3 0.7 0.0 1.8 0.6 1.5 11.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 1.3 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 703.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.8 2.7 2.7 0.9 4.6 8.5 4.4 6.8 3.5 4.6 11.5 6.9 0.0 2.0 0.0 3.6 10.8 6.6 18.8 0.0 0.0 1117.6 324.2 0.1 0.0 48.2 1.8 0.0 0.0 7.0 0.0 0.0 9.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 2.5 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.4 0.0 1.6 0.0 0.0 1.5 403.8 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 0.0 13.1 0.0 0.1 147.1 0.0 0.0 0.0 9.2 0.0 0.0 0.0 1.7 0.0 2.5 0.0 0.0 13.7 PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697261 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1255.9;Inhibitory neurons: 330.9;Oligodendrocyte precursor cells: 281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" 25.7 8.9 27.2 5.6 30.1 3.8 18.6 23.5 26.9 8.7 13.2 7.6 1.5 7.8 3.8 9.8 10.9 3.8 13.3 22.7 31.2 21.8 9.8 15.1 8.8 38.4 41.0 15.2 23.1 1.8 13.7 6.0 28.2 11.9 2.2 15.0 14.1 4.4 5.4 4.9 8.7 3.5 28.7 9.4 12.6 2.5 42.7 8.4 9.0 5.0 7.4 12.0 9.2 20.1 4.2 1.0 4.5 6.8 2.8 5.1 3.9 6.0 2.9 0.8 0.4 0.0 6.4 4.6 1.4 3.6 1.7 2.0 6.7 6.0 1.1 9.3 3.0 0.7 7.6 3.4 0.7 1.4 9.8 3.6 2.2 0.9 2.5 0.5 3.2 6.5 0.3 16.9 2.3 7.0 10.9 2.8 6.6 1.8 7.7 15.2 0.9 4.2 9.7 5.4 4.7 13.0 1.7 3.3 4.1 4.8 3.0 4.7 3.7 1.8 1.0 2.4 2.9 13.2 6.2 3.7 14.4 4.6 1.6 0.7 1.4 10.3 11.1 2.6 5.7 0.5 6.9 9.2 0.9 1.3 8.2 8.3 1.7 5.2 4.1 0.1 2.8 4.1 27.2 30.1 23.5 26.9 22.7 31.2 38.4 41.0 28.2 28.7 42.7 20.1 102.6 9.6 1.1 1255.9 9.6 5.4 55.6 4.6 8.0 15.2 7.7 4.1 6.9 21.5 4.6 0.0 2.1 7.9 84.0 5.8 21.5 43.3 0.2 13.7 5.7 59.8 6.0 4.0 88.4 49.1 13.6 18.9 8.2 30.9 5.1 7.7 21.4 10.1 13.8 74.0 330.9 1.3 4.1 21.4 22.3 1.4 5.0 17.7 10.6 103.0 20.2 34.6 84.5 281.5 9.7 38.7 4.4 14.7 28.0 32.9 0.1 21.2 3.4 21.8 26.3 66.5 25.7 0.4 3.8 9.0 4.3 3.4 75.7 2.7 3.8 54.3 PITX3 ASMD ENSG00000107859 "Paired like homeodomain 3" O75364 10 102230186-102241512 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.5;skeletal muscle: 16.5;tongue: 6.0" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 22.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "midbrain: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "RH-30: 30.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 9.1" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.13e-2)" "unprognostic (4.07e-1)" "unprognostic (5.15e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (6.04e-5)" "unprognostic (6.30e-3)" "unprognostic (2.02e-1)" "unprognostic (6.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.73e-2)" "unprognostic (1.76e-2)" "unprognostic (6.76e-3)" "unprognostic (4.13e-2)" 1.2 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.1 0.2 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 16.5 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.0 5.5 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 22.1 0.3 1.4 1.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 PJA1 "FLJ11830, RNF70" ENSG00000181191 "Praja ring finger ubiquitin ligase 1" Q8NG27 X 69160851-69165521 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 160.0" "Cell type enhanced" "Detected in many" "Early spermatids: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 99.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000595 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA000595: AB_1079826" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (4.03e-2)" "unprognostic (2.58e-3)" "unprognostic (5.44e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-2)" "unprognostic (3.82e-3)" "unprognostic (1.84e-2)" "unprognostic (6.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.44e-5)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-1)" 22.9 14.5 46.8 8.7 50.5 3.6 19.4 37.2 78.0 19.9 33.0 15.4 6.4 16.4 160.0 12.3 16.0 11.1 15.0 47.1 48.9 19.2 9.4 13.8 10.0 38.9 41.7 25.8 14.5 38.7 28.1 17.3 40.6 15.3 7.6 17.6 10.6 32.4 7.9 14.6 11.1 16.0 40.1 13.3 14.0 26.4 49.0 10.0 22.7 8.8 12.1 17.4 15.1 43.5 27.3 19.6 62.9 43.7 21.3 22.5 18.7 17.8 22.0 16.7 22.3 17.1 25.8 4.4 26.7 28.1 39.2 24.0 99.0 34.9 21.2 20.2 33.0 8.1 16.0 10.9 25.7 4.9 14.4 23.1 23.6 28.6 17.0 15.8 19.0 13.2 7.8 3.0 16.9 14.1 2.1 8.4 43.4 23.1 32.0 20.0 28.2 6.9 23.4 22.6 46.4 30.7 28.6 4.9 22.2 50.1 7.7 7.0 17.8 13.9 22.6 41.7 8.3 0.0 0.2 9.1 15.3 13.1 19.4 6.6 6.8 2.1 29.6 9.2 34.3 16.4 26.1 27.5 7.3 22.8 26.5 31.3 2.3 30.0 6.5 8.9 17.5 19.4 46.8 50.5 37.2 78.0 47.1 48.9 38.9 41.7 40.6 40.1 49.0 43.5 4.7 16.0 4.8 2.9 9.7 41.0 19.4 30.8 23.9 16.8 5.0 6.2 7.1 4.3 14.8 3.7 8.4 35.6 5.9 1.0 15.6 24.9 74.7 3.9 10.4 6.6 5.4 10.8 8.1 11.7 15.3 18.2 7.1 5.8 4.5 27.9 6.8 1.7 7.0 5.0 8.3 3.6 6.1 2.9 9.9 32.7 27.1 5.7 5.4 2.8 2.9 30.6 14.4 5.0 3.7 18.0 1.7 19.5 7.7 17.0 0.5 6.5 4.4 6.1 6.6 9.4 16.3 1.4 1.5 11.2 29.5 20.8 11.2 27.0 2.6 22.5 PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048021-42058517 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 85.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 71.9;Fibroblasts: 55.4;Leydig cells: 137.6;Peritubular cells: 112.1;Rod photoreceptor cells: 95.9;Theca cells: 135.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 85.9;ASC diff: 61.7;CACO-2: 101.0;HHSteC: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" NA NA 80000 "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA026427: AB_10600773, HPA026442: AB_10601237, HPA026526: AB_10602416" "unprognostic (6.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.59e-3)" "unprognostic (8.31e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (5.79e-3)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.08e-2)" "unprognostic (2.62e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-3)" 25.7 11.3 3.1 4.9 3.8 0.8 16.1 0.8 6.2 31.8 6.4 20.3 10.7 25.7 2.1 2.2 24.2 3.3 37.6 4.8 1.0 10.7 6.9 16.5 2.1 1.5 1.6 50.1 7.0 1.1 6.8 3.6 1.3 12.2 5.7 5.3 20.7 5.8 85.5 3.8 13.7 9.8 1.4 9.6 9.6 14.8 2.1 6.4 5.1 27.7 1.4 32.5 17.4 4.7 0.0 5.5 14.0 85.9 61.7 0.7 5.3 0.2 0.0 1.2 1.5 101.0 0.2 0.0 0.3 1.7 1.8 0.0 1.3 0.0 0.0 8.1 3.5 0.2 3.3 27.0 53.7 0.0 1.2 5.7 0.3 0.2 0.0 0.6 0.7 0.0 1.2 0.0 0.3 0.3 0.0 0.3 23.8 6.8 1.7 0.0 27.3 0.0 0.0 0.0 2.8 5.1 1.3 0.0 0.2 16.3 0.1 0.7 0.0 0.6 2.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.8 0.8 6.2 4.8 1.0 1.5 1.6 1.3 1.4 2.1 4.7 28.8 19.2 0.5 4.2 0.3 3.2 0.2 0.0 0.0 4.7 1.3 2.0 9.2 1.5 0.0 1.8 16.7 0.5 0.6 22.8 0.0 2.1 1.1 6.0 31.4 3.1 71.9 0.0 22.8 1.3 1.3 55.4 2.6 26.3 0.0 4.5 2.9 2.7 0.6 0.0 3.3 18.6 0.0 0.6 3.1 5.4 137.6 0.6 1.8 3.7 0.0 21.3 0.0 10.1 1.8 1.9 16.0 112.1 0.0 0.8 15.2 3.9 0.0 95.9 13.1 14.2 15.1 0.7 1.7 0.0 1.8 0.3 0.8 135.4 35.9 0.1 PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 138.4;parathyroid gland: 65.8;seminal vesicle: 67.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Endothelial cells: 14.3;Hepatocytes: 26.0;Langerhans cells: 15.6;Peritubular cells: 14.3" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "SK-MEL-30: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" NA NA 420000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" 4.9 0.7 12.1 3.5 11.3 0.3 3.4 11.6 16.3 4.7 26.8 2.7 1.1 4.7 138.4 1.5 5.7 2.8 4.9 12.5 12.0 7.7 39.6 21.2 15.6 13.2 12.3 1.1 3.7 65.8 1.7 9.8 13.2 9.1 2.5 1.0 3.5 67.2 16.2 0.8 3.5 8.8 13.4 1.0 4.4 3.7 14.7 1.6 6.9 3.1 8.7 3.9 1.9 12.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.3 0.5 0.1 0.0 0.2 0.0 0.0 25.0 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.1 11.3 11.6 16.3 12.5 12.0 13.2 12.3 13.2 13.4 14.7 12.4 6.5 0.0 1.7 0.0 0.0 0.6 0.5 0.4 0.6 0.0 0.1 0.1 2.8 2.8 1.0 14.7 0.0 0.2 0.1 0.0 1.9 4.7 6.6 0.1 0.1 14.3 1.8 0.0 0.2 2.2 0.0 1.6 0.0 0.9 1.3 0.7 7.9 26.0 1.6 0.0 0.1 0.1 0.0 1.0 15.6 3.2 0.3 5.4 1.8 4.7 4.2 0.0 0.0 0.0 0.0 1.3 0.6 14.3 0.0 0.5 0.0 5.1 7.5 0.1 0.0 0.9 5.9 0.0 0.2 0.0 0.6 1.9 0.1 0.0 0.1 0.2 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 67.9" "Cell type enhanced" "Detected in single" "dendritic cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.3;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 10 "B-cells: 17.3" "Cell line enriched" "Detected in some" 8 "U-266/70: 128.9" HPA058997 Approved Approved Mitochondria NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" 0.3 0.0 0.6 0.8 0.6 0.1 9.1 0.5 0.9 0.9 0.3 11.2 67.9 0.3 1.2 1.5 4.7 0.6 0.2 0.5 0.5 8.6 4.6 3.6 0.3 0.7 0.6 0.2 0.0 0.0 0.2 0.2 0.6 0.4 13.7 0.0 0.9 0.5 0.0 0.3 42.5 0.3 0.5 0.7 12.4 0.5 0.6 0.3 0.9 0.0 0.3 1.3 0.2 1.1 0.4 1.7 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 0.1 0.3 15.6 0.0 0.9 0.0 0.4 1.0 0.6 0.2 0.1 0.2 0.0 0.1 1.0 0.1 0.2 0.0 0.1 0.1 1.2 0.3 0.0 0.7 0.0 0.0 0.0 6.7 0.0 0.0 0.2 0.3 0.1 8.7 1.9 0.0 0.0 1.5 0.6 0.0 0.0 0.2 0.1 4.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 0.1 0.0 128.9 16.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.9 17.3 0.2 1.0 0.1 8.2 0.2 0.7 0.1 1.6 0.0 0.9 0.0 3.9 0.6 0.6 0.5 0.9 0.5 0.5 0.7 0.6 0.6 0.5 0.6 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 318.7;brain: 394.8" "Cell type enhanced" "Detected in some" "Adipocytes: 80.5;Cardiomyocytes: 151.9;Cytotrophoblasts: 137.4;Extravillous trophoblasts: 365.5;Hofbauer cells: 71.0;Syncytiotrophoblasts: 290.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 187.8" "Group enriched" "Detected in all" 6 "dendritic cells: 187.8;T-cells: 55.0" "Cell line enhanced" "Detected in many" "A549: 135.1;ASC diff: 148.2;CAPAN-2: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" 318.7 36.2 208.5 10.2 287.0 3.1 166.8 234.7 261.6 13.3 142.8 32.8 8.7 17.6 26.6 13.2 33.0 29.1 103.0 197.7 215.3 65.0 76.5 37.6 11.6 283.0 250.7 73.4 32.4 28.6 33.4 40.3 279.8 16.4 7.6 26.6 28.9 29.9 108.9 10.7 21.8 15.8 241.2 15.9 31.9 54.7 237.1 7.1 41.2 118.7 4.4 26.7 9.6 394.8 87.7 135.1 3.7 0.2 148.2 25.1 24.1 3.2 26.9 22.3 11.2 30.8 247.1 0.0 55.3 6.9 72.4 4.4 127.4 6.8 16.9 108.0 5.0 1.3 33.3 5.4 87.8 0.0 1.3 15.2 0.7 55.4 2.2 88.1 35.4 0.0 1.6 9.6 24.0 15.3 0.2 0.6 10.8 55.0 43.0 0.0 0.0 8.7 71.2 12.3 1.7 9.7 18.0 51.5 28.7 54.6 111.6 4.5 52.2 10.0 0.7 34.0 7.7 39.6 28.0 0.3 40.1 0.0 1.0 0.1 21.1 0.1 55.0 9.1 30.3 7.4 12.1 40.5 6.4 1.2 3.9 30.0 1.3 21.0 0.6 187.8 9.3 27.2 208.5 287.0 234.7 261.6 197.7 215.3 283.0 250.7 279.8 241.2 237.1 394.8 80.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.9 0.0 0.0 0.0 0.0 137.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 365.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 290.6 2.0 0.0 0.0 0.0 PLAAT5 "HRASLS5, HRLP5, iNAT, PLAAT-5" ENSG00000168004 "Phospholipase A and acyltransferase 5" Q96KN8 11 63461404-63491194 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 16.5;pancreas: 13.6;testis: 53.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Syncytiotrophoblasts: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 3.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 64 "basophil: 5.4;eosinophil: 16.4" "Lineage enriched" "Detected in single" 97 "granulocytes: 16.4" "Group enriched" "Detected in some" 5 "HAP1: 11.4;NB-4: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042493 Uncertain "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA042493: AB_10797499" "unprognostic (3.16e-1)" "unprognostic (3.45e-2)" "unprognostic (2.83e-3)" "unprognostic (4.24e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (7.11e-3)" "unprognostic (2.14e-1)" "unprognostic (6.66e-2)" "unprognostic (9.46e-2)" "unprognostic (8.89e-3)" "unprognostic (3.15e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-5)" "unprognostic (1.52e-1)" "unprognostic (1.21e-2)" "unprognostic (2.57e-3)" "unprognostic (4.50e-4)" 16.5 0.2 1.2 0.3 0.9 0.1 3.3 0.7 0.8 0.1 0.0 0.7 0.2 0.5 0.2 0.8 0.9 0.6 0.6 1.0 1.3 0.1 0.0 0.6 0.1 1.5 0.5 0.6 13.6 0.0 0.0 0.0 1.0 0.4 0.2 0.5 0.8 1.3 0.1 0.2 0.3 1.4 1.1 0.1 0.5 53.4 0.8 0.0 0.1 0.1 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.7 0.8 1.0 1.3 1.5 0.5 1.0 1.1 0.8 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 365.9;esophagus: 92.0;intestine: 236.0;lymphoid tissue: 155.1;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1118.2;Distal enterocytes: 1514.4;Extravillous trophoblasts: 572.2;NK-cells: 1103.0;Paneth cells: 865.7;Respiratory ciliated cells: 549.6" "Cancer enhanced" "Detected in many" "stomach cancer: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2310.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 183.2;CAPAN-2: 510.7;HL-60: 329.1;NB-4: 160.1;RPMI-8226: 238.2;THP-1: 187.8;U-937: 149.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA040465: AB_10794875, HPA077912: AB_2686870" "unprognostic (6.82e-5)" "prognostic favorable (3.03e-4)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.14e-1)" "unprognostic (1.94e-3)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (7.44e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-7)" "unprognostic (3.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" 9.2 2.0 1.8 81.3 2.0 365.9 3.8 2.8 2.4 32.8 1.4 236.0 78.9 2.7 1.2 92.0 18.7 6.5 2.8 1.5 1.7 2.6 35.4 41.2 93.8 7.8 2.7 1.0 1.6 0.5 2.0 33.7 5.5 3.7 163.3 1.1 6.6 2.3 2.0 1.0 88.5 18.5 2.3 155.1 117.5 0.8 2.4 40.5 2.6 0.8 137.5 11.0 5.8 3.7 183.2 1.3 0.5 1.1 0.0 0.2 28.6 4.6 1.1 11.1 13.7 3.5 510.7 30.7 1.5 52.3 17.0 18.7 3.2 1.4 41.6 0.2 0.6 0.8 33.4 15.2 1.8 329.1 1.7 0.9 3.6 1.8 2.4 0.3 0.8 16.0 0.4 2.6 29.5 0.8 62.6 160.1 1.0 14.4 0.9 8.0 10.6 238.2 0.9 5.4 25.8 0.5 1.2 29.1 0.6 9.0 1.6 187.8 1.3 1.1 31.7 0.9 0.9 1.8 0.4 81.7 2.3 149.7 0.2 49.2 139.2 95.9 392.1 635.8 299.4 523.8 185.1 229.2 129.5 481.1 225.9 263.4 29.7 1053.3 358.9 2310.7 13.8 577.1 1.8 2.0 2.8 2.4 1.5 1.7 7.8 2.7 5.5 2.3 2.4 3.7 4.3 195.5 39.2 0.3 247.4 0.4 1.7 77.3 0.0 0.3 0.9 1.4 0.5 2.8 119.1 0.0 0.0 18.5 1118.2 1514.4 0.0 0.3 0.5 45.6 1.1 95.0 86.8 58.4 0.1 3.6 572.2 3.1 119.8 2.9 26.6 0.6 141.0 8.4 21.7 1.7 0.1 231.2 67.1 384.5 7.4 0.6 0.0 213.3 7.2 1.0 157.3 1.2 1103.0 0.0 0.2 99.0 865.7 0.0 35.7 1.1 374.4 1.4 549.6 0.3 6.6 0.7 8.0 0.2 0.8 10.1 0.1 14.2 150.6 0.1 104.2 9.0 PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.7;Hofbauer cells: 105.6;Kupffer cells: 109.4;Macrophages: 116.3;monocytes: 192.8;Paneth cells: 105.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Cell line enhanced" "Detected in many" "AN3-CA: 48.6;BEWO: 98.4;CAPAN-2: 245.6;MCF7: 46.3" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" 29.4 5.6 2.1 33.7 2.5 285.9 27.8 2.4 3.7 22.4 25.9 58.8 28.2 13.5 10.6 56.3 16.6 33.1 32.6 2.1 2.4 26.3 10.6 64.0 9.2 3.5 3.2 4.4 30.0 3.2 3.4 35.9 3.2 10.2 79.2 0.8 11.9 15.3 9.9 24.8 42.6 28.1 3.1 25.2 36.6 10.0 2.8 7.8 6.1 17.2 32.7 58.5 29.6 4.8 7.1 5.0 0.5 48.6 0.3 0.0 98.4 0.2 0.0 3.0 2.4 14.1 245.6 0.0 1.4 1.0 0.4 9.4 0.0 0.0 0.5 0.0 0.1 0.0 6.4 0.0 3.8 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.1 46.3 0.1 0.2 16.5 0.7 0.3 0.1 0.1 0.5 0.7 28.9 0.0 0.4 30.2 14.8 1.9 26.5 9.0 9.6 0.0 0.5 0.4 0.0 0.6 8.7 23.7 0.2 0.0 0.1 0.4 0.4 662.9 5.8 1.0 204.4 0.6 3.6 0.5 0.4 357.3 0.8 0.7 0.7 443.8 1.7 73.5 4.1 0.9 423.2 2.1 2.5 2.4 3.7 2.1 2.4 3.5 3.2 3.2 3.1 2.8 4.8 15.5 9.6 8.6 0.3 2.9 6.8 8.8 4.9 6.8 0.0 11.9 6.6 16.5 30.0 20.4 33.1 0.0 94.5 1.5 67.8 11.7 13.1 51.8 2.5 9.1 7.2 9.1 1.7 1.6 46.5 187.7 59.6 13.3 0.9 5.1 5.9 4.6 2.9 105.6 0.0 0.9 31.3 6.1 109.4 68.6 5.8 26.1 116.3 5.4 7.5 192.8 1.6 1.0 1.5 0.2 28.6 105.9 27.8 3.6 3.8 52.8 15.7 19.0 0.2 0.0 12.0 10.4 17.4 12.0 17.8 19.9 70.3 1.6 6.1 75.2 30.1 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "dendritic cells: 22.6;granulocytes: 26.6;Hofbauer cells: 30.3;Kupffer cells: 46.6;Macrophages: 41.7;Microglial cells: 39.4;monocytes: 20.9;NK-cells: 26.8;T-cells: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 78.6;HMC-1: 93.4;THP-1: 28.1;U-937: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 5.9 4.0 3.8 29.2 3.9 52.4 2.5 3.8 5.4 3.3 3.4 5.1 6.1 2.7 1.4 3.0 4.5 9.7 3.0 4.0 5.6 1.9 6.3 16.8 28.7 8.4 7.1 1.5 1.3 1.3 2.1 7.0 7.3 2.6 8.0 0.5 5.4 4.0 1.2 1.9 10.4 7.3 6.2 40.7 5.5 1.3 7.7 20.5 2.2 1.7 22.2 7.3 1.8 9.6 0.4 0.0 0.6 0.0 0.0 0.0 10.5 0.0 0.1 0.0 0.0 0.1 19.1 1.5 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 78.6 0.0 0.0 0.0 16.9 93.4 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.7 4.3 0.0 0.0 4.7 9.2 0.9 0.0 0.2 13.7 2.0 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.2 5.1 0.0 28.1 10.1 0.0 9.1 0.0 0.0 0.0 0.0 3.7 0.0 53.2 0.0 1.7 2.6 5.3 1.8 2.7 1.2 0.4 0.9 0.9 2.7 0.5 0.9 1.0 4.2 1.2 2.7 1.0 1.9 1.5 3.8 3.9 3.8 5.4 4.0 5.6 8.4 7.1 7.3 6.2 7.7 9.6 0.9 6.4 16.8 0.3 9.6 0.9 0.1 0.1 0.6 0.1 1.9 2.5 3.3 1.5 3.2 1.8 0.0 0.5 22.6 0.2 0.0 0.1 2.2 0.2 0.5 1.7 0.0 8.0 1.8 0.0 0.5 1.9 0.0 0.2 26.6 0.1 1.1 0.4 30.3 0.0 0.8 1.7 0.0 46.6 15.5 0.6 0.3 41.7 3.6 39.4 20.9 0.0 26.8 0.5 0.2 0.4 0.3 0.0 5.7 0.0 0.0 0.9 4.4 0.2 0.0 0.4 0.7 0.5 2.3 0.3 0.6 0.4 20.8 0.3 2.0 0.0 PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505532 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.8;skin 1: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.5;Cone photoreceptor cells: 75.0;Oligodendrocytes: 37.4;Rod photoreceptor cells: 169.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HBEC3-KT: 130.9;hTCEpi: 58.9;hTERT-HME1: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072705 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA072705: AB_2732211" "unprognostic (2.06e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-3)" "unprognostic (3.84e-3)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (7.39e-2)" "unprognostic (7.70e-2)" "unprognostic (7.58e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (6.61e-3)" "unprognostic (8.43e-2)" "unprognostic (1.07e-1)" "unprognostic (8.64e-2)" "unprognostic (5.80e-2)" 0.6 1.4 1.0 3.9 1.7 2.2 6.2 7.9 4.8 6.3 0.0 1.1 2.2 0.3 1.7 19.3 3.2 2.9 0.2 2.4 1.0 0.8 2.1 1.8 5.3 3.3 3.1 0.1 5.1 0.0 7.9 0.4 3.6 14.6 0.8 44.8 16.4 5.8 0.2 59.6 3.3 0.1 1.2 5.5 2.0 0.6 6.9 4.4 1.7 0.0 6.5 9.1 18.3 7.2 0.3 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.2 0.0 17.1 0.0 130.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 58.9 0.0 32.8 0.0 0.0 0.0 0.0 3.1 0.3 0.6 0.0 0.0 0.1 1.9 1.4 0.1 0.1 0.0 0.2 6.1 14.7 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 0.6 0.2 1.0 1.7 7.9 4.8 2.4 1.0 3.3 3.1 3.6 1.2 6.9 7.2 0.2 0.0 1.7 2.9 6.1 15.4 14.5 22.8 10.8 102.5 1.7 5.5 3.3 2.8 10.8 0.0 75.0 0.0 7.3 0.7 1.9 0.1 0.1 0.7 0.2 0.7 1.2 0.0 9.3 0.0 0.0 0.4 1.5 1.4 0.0 0.1 0.0 4.9 0.1 26.9 19.8 1.9 2.0 0.3 1.1 0.2 0.0 0.5 3.6 1.9 0.4 14.9 7.2 2.5 37.4 0.5 0.6 0.0 1.9 4.9 3.8 33.5 5.8 169.0 0.0 0.0 1.0 0.2 0.3 13.0 14.6 0.0 7.0 0.1 0.5 9.2 PLCXD2 FLJ31579 ENSG00000240891 "Phosphatidylinositol specific phospholipase C X domain containing 2" Q0VAA5 3 111674676-111846447 "Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 7.3;retina: 14.8" "Cell type enhanced" "Detected in many" "Collecting duct cells: 60.7;Distal tubular cells: 160.4;Hepatocytes: 168.6;Proximal tubular cells: 196.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 5 "dendritic cells: 3.8;NK-cells: 1.1;T-cells: 1.8" "Cell line enhanced" "Detected in many" "HBF TERT88: 7.1" "Low region specificity" "Detected in all" HPA055947 Uncertain Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055947: AB_2682981" "unprognostic (2.68e-1)" "unprognostic (6.43e-2)" "unprognostic (7.26e-2)" "unprognostic (2.42e-1)" "unprognostic (3.09e-2)" "unprognostic (2.76e-2)" "unprognostic (1.36e-1)" "unprognostic (4.64e-1)" "unprognostic (3.47e-1)" "unprognostic (1.99e-2)" "unprognostic (3.38e-2)" "unprognostic (2.04e-1)" "prognostic favorable (1.23e-7)" "unprognostic (7.47e-2)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "prognostic favorable (2.99e-4)" 0.3 0.3 2.6 1.6 2.9 4.6 0.2 0.7 7.3 0.3 0.0 1.2 2.8 0.3 0.2 0.5 0.2 0.7 0.3 3.9 1.6 0.6 1.0 0.6 2.9 4.1 4.5 0.2 0.6 0.1 1.4 1.0 4.1 0.3 1.5 14.8 0.9 0.2 0.2 0.6 2.7 0.3 2.2 1.6 0.9 1.0 3.5 2.7 1.3 0.1 2.2 0.5 0.3 1.9 2.3 2.1 2.0 0.9 0.0 0.1 0.6 4.0 1.9 3.7 3.2 1.4 1.1 1.7 2.0 0.2 1.2 5.6 0.8 3.7 7.1 0.5 1.0 0.4 4.1 1.3 0.3 0.5 2.0 0.0 0.7 1.2 2.2 3.4 2.0 2.1 0.0 4.0 0.4 0.2 1.2 0.4 0.7 1.5 5.1 1.1 2.8 1.6 1.7 2.3 0.4 3.4 0.8 0.5 0.8 2.2 0.3 0.1 2.0 0.8 5.0 0.4 0.8 4.8 0.7 0.3 0.4 0.3 0.2 0.3 0.0 0.0 1.8 0.0 1.8 0.3 0.9 1.8 0.1 0.4 0.4 0.9 0.1 1.1 0.0 3.8 0.9 0.3 2.6 2.9 0.7 7.3 3.9 1.6 4.1 4.5 4.1 2.2 3.5 1.9 0.4 19.2 2.2 3.3 2.3 0.1 9.9 17.1 7.4 0.8 2.9 1.8 3.7 22.8 3.5 60.7 4.2 0.0 8.4 1.6 160.4 44.2 11.9 0.9 0.2 0.7 25.1 0.0 11.7 50.1 0.0 0.4 7.1 1.5 0.0 5.4 0.4 168.6 0.0 6.7 6.0 7.8 2.0 1.6 0.0 12.0 0.3 1.8 0.0 3.7 0.0 0.0 2.1 7.5 0.9 50.1 0.2 0.4 3.9 7.9 1.0 196.6 1.0 3.5 0.0 0.0 1.7 0.5 0.5 2.2 0.1 0.0 5.3 0.5 1.5 14.1 PLCXD3 ENSG00000182836 "Phosphatidylinositol specific phospholipase C X domain containing 3" Q63HM9 5 41306952-41510628 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;heart muscle: 33.2;ovary: 22.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 138.2;Endometrial stromal cells: 58.7;Enteroendocrine cells: 42.4;Inhibitory neurons: 163.5;Microglial cells: 52.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 8.5;PC-3: 7.5;SH-SY5Y: 34.3;TIME: 18.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046849 Uncertain Approved "Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA046849: AB_2679838" "unprognostic (1.71e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (7.04e-3)" "unprognostic (1.43e-1)" "unprognostic (2.44e-1)" "unprognostic (4.90e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-2)" "unprognostic (3.12e-1)" "unprognostic (6.38e-3)" "unprognostic (2.57e-1)" "unprognostic (2.73e-2)" "unprognostic (2.15e-3)" "unprognostic (5.91e-5)" "unprognostic (5.11e-2)" "unprognostic (6.75e-2)" 3.9 12.7 4.5 0.5 4.1 0.0 2.4 17.8 4.2 2.9 1.1 0.9 0.5 1.1 0.9 0.6 3.4 2.4 33.2 3.4 9.5 5.9 1.6 1.8 1.6 8.2 10.4 22.5 3.6 0.3 5.3 0.1 16.0 1.0 0.6 0.7 0.4 1.0 0.5 0.7 1.2 1.2 7.7 0.2 5.0 0.4 12.1 0.5 1.5 0.7 0.2 1.4 4.0 6.3 0.0 3.7 0.0 0.0 0.0 0.0 0.0 1.8 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.4 34.3 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 4.1 17.8 4.2 3.4 9.5 8.2 10.4 16.0 7.7 12.1 6.3 8.7 0.0 0.0 7.5 0.1 0.1 0.1 0.0 0.0 0.7 0.1 0.0 138.2 5.7 0.0 0.0 0.0 0.1 0.0 0.1 3.9 0.3 0.9 1.7 58.7 13.6 42.4 5.3 27.8 0.0 2.0 10.3 0.0 1.1 0.0 33.4 33.2 0.4 0.1 1.7 163.5 2.2 0.0 0.6 0.3 4.4 7.8 0.2 0.0 52.5 0.0 0.4 0.0 7.5 1.3 0.9 0.0 0.4 0.0 0.3 0.1 10.4 0.0 0.2 6.6 0.2 2.9 0.2 0.0 0.2 0.0 0.1 0.3 9.7 0.1 0.1 PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40380439 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 711.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 688.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 1727.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 1727.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 450000 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favorable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" 169.3 200.0 143.3 78.4 159.7 48.3 138.4 46.0 229.7 139.4 54.0 131.4 71.7 155.7 84.7 84.9 133.5 96.7 206.1 202.5 294.4 130.2 121.3 181.5 98.1 132.4 128.5 199.0 151.0 105.9 711.9 123.4 137.9 133.4 49.2 51.4 138.7 106.2 105.1 120.5 105.3 79.1 63.8 197.0 126.5 77.7 197.7 44.3 120.8 82.3 41.4 126.2 126.0 129.6 85.6 257.8 163.7 259.1 444.2 210.2 124.5 206.5 208.6 146.4 166.6 49.4 93.8 36.9 211.0 180.9 47.8 39.3 39.9 81.2 63.5 138.4 145.3 39.9 82.1 63.2 302.7 16.8 435.1 402.5 167.0 112.1 76.6 244.2 125.0 59.3 142.5 144.5 106.7 111.5 29.5 79.6 107.4 138.7 52.8 37.0 124.5 154.2 75.2 63.2 116.7 193.9 99.0 60.6 113.8 169.5 83.6 283.2 222.3 122.8 58.5 105.6 47.0 148.9 173.3 38.8 197.7 66.2 77.9 1727.4 256.7 378.7 75.0 129.5 62.0 34.4 59.5 67.7 235.0 28.1 60.8 61.3 25.7 102.3 64.2 34.7 64.5 208.6 143.3 159.7 46.0 229.7 202.5 294.4 132.4 128.5 137.9 63.8 197.7 129.6 66.7 32.1 69.6 59.4 27.0 35.4 93.6 263.1 39.9 101.5 45.9 61.2 22.0 45.8 90.4 57.0 33.3 158.2 27.2 42.5 21.5 52.5 8.7 32.0 49.8 53.9 72.8 18.7 99.1 58.3 107.2 158.8 38.2 31.5 60.3 134.7 88.2 43.1 688.4 121.1 113.4 41.3 126.1 280.9 59.1 15.7 151.6 261.3 92.5 50.6 54.2 94.1 35.0 53.3 70.2 54.3 42.6 143.7 85.8 57.9 78.8 37.1 35.2 47.6 19.7 73.1 59.7 24.2 67.9 32.4 33.4 195.9 28.8 114.1 41.6 68.2 PLEK P47 ENSG00000115956 Pleckstrin P08567 2 68365282-68397453 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 604.8" "Cell type enhanced" "Detected in many" "dendritic cells: 310.7;Hofbauer cells: 220.3;Kupffer cells: 213.9;Langerhans cells: 456.5;Macrophages: 412.7;monocytes: 178.3;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 552.9;HL-60: 126.7;HMC-1: 202.5;NB-4: 187.5;THP-1: 215.6;U-266/84: 147.8;U-698: 147.1;U-937: 342.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031838, HPA057341" Enhanced Approved Nucleoli NA NA 380000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "HPA031838: AB_10602146, HPA057341: AB_2732609" "unprognostic (2.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.52e-3)" "unprognostic (3.52e-1)" "unprognostic (3.08e-2)" "unprognostic (4.67e-2)" "unprognostic (3.40e-2)" "unprognostic (4.00e-2)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (3.57e-1)" "unprognostic (4.42e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" 36.4 9.8 4.9 99.4 7.1 604.8 8.2 6.0 10.0 6.9 6.5 13.2 10.4 4.7 3.3 6.0 7.2 21.0 5.4 4.9 5.3 4.0 27.5 35.6 129.9 8.0 6.1 2.6 2.7 2.7 1.9 29.2 8.1 4.2 18.8 0.5 5.7 3.1 1.7 3.4 13.0 22.2 7.3 93.5 11.3 3.2 7.2 33.7 3.8 5.2 118.2 52.3 2.5 12.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 93.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 552.9 0.0 0.0 0.0 126.7 202.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 58.9 0.0 0.0 0.2 187.5 0.0 0.0 0.0 1.5 0.1 27.3 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.0 215.6 0.1 0.0 0.4 0.1 0.5 7.9 147.8 147.1 0.2 342.5 0.1 231.9 297.5 429.2 298.5 351.6 157.6 157.7 52.2 218.7 229.6 103.6 14.5 161.8 573.9 249.5 390.8 474.8 5.7 606.9 4.9 7.1 6.0 10.0 4.9 5.3 8.0 6.1 8.1 7.3 7.2 12.3 3.4 19.2 24.6 0.0 77.0 6.5 0.3 0.0 0.0 0.0 1.4 3.7 2.3 1.5 15.5 1.8 0.0 1.2 310.7 0.0 0.0 0.2 1.5 0.2 0.3 6.3 0.0 21.9 0.6 0.6 1.8 10.2 1.5 0.3 62.0 0.0 5.7 1.5 220.3 0.0 0.2 0.0 0.0 213.9 456.5 5.1 0.6 412.7 17.8 20.6 178.3 0.0 355.3 0.0 0.1 0.1 0.1 0.4 48.4 0.0 0.0 0.7 13.1 0.1 13.1 1.1 1.8 0.8 0.9 0.6 6.7 2.6 78.3 0.4 0.0 0.3 PLEKHD1 UPF0639 ENSG00000175985 "Pleckstrin homology and coiled-coil domain containing D1" A6NEE1 14 69484692-69531551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;parathyroid gland: 6.0;retina: 8.8" "Group enriched" "Detected in some" 13 "Bipolar cells: 60.9;Horizontal cells: 230.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 3.7" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.7" "Cell line enhanced" "Detected in some" "OE19: 1.1;SK-BR-3: 2.4;T-47d: 2.3;U-266/70: 1.0" "Region enhanced" "Detected in many" "cerebellum: 30.0" "Low region specificity" "Detected in many" HPA051875 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "HPA051875: AB_2681648" "unprognostic (8.73e-2)" "unprognostic (4.64e-3)" "unprognostic (3.73e-2)" "unprognostic (4.03e-2)" "unprognostic (7.58e-2)" "unprognostic (3.15e-3)" "unprognostic (1.44e-1)" "unprognostic (1.64e-3)" "unprognostic (3.28e-1)" "unprognostic (1.83e-1)" "unprognostic (4.56e-3)" "unprognostic (1.22e-1)" "unprognostic (5.49e-2)" "unprognostic (8.08e-2)" "unprognostic (2.28e-1)" "unprognostic (2.74e-2)" "unprognostic (1.42e-2)" 0.1 0.2 1.2 0.1 0.5 0.5 0.6 8.1 2.4 0.3 0.0 0.0 0.2 0.1 1.6 0.1 0.1 0.1 0.1 0.3 1.4 1.4 0.0 0.2 0.9 1.4 3.2 0.1 0.2 6.0 0.3 0.1 1.6 0.1 0.0 8.8 1.6 0.3 0.1 1.5 0.1 0.0 0.4 0.2 0.2 1.2 4.5 0.1 2.2 0.0 0.2 0.0 0.0 1.1 0.1 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.4 0.1 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.7 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.1 0.3 0.1 0.1 1.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 1.2 0.5 8.1 2.4 0.3 1.4 1.4 3.2 1.6 0.4 4.5 1.1 0.5 0.0 7.3 0.3 0.0 0.4 1.8 0.1 0.0 60.9 0.6 0.4 1.3 0.0 2.0 0.0 4.2 0.1 11.2 0.1 3.9 0.1 0.5 0.4 0.2 1.0 0.0 0.0 6.3 0.2 0.1 0.6 0.0 0.6 1.3 0.1 0.4 0.0 0.1 230.5 3.3 0.0 0.0 0.0 0.6 0.1 0.0 1.0 0.0 0.0 0.6 1.7 1.0 0.0 0.1 0.3 0.0 0.0 0.0 1.4 0.2 0.5 0.9 5.9 0.0 1.4 0.6 0.8 0.3 0.0 0.3 0.1 2.3 0.2 0.1 0.7 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PLEKHG6 "FLJ10665, MYOGEF" ENSG00000008323 "Pleckstrin homology and RhoGEF domain containing G6" Q3KR16 12 6310436-6328506 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.9;intestine: 43.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 117.9;Extravillous trophoblasts: 56.2;Paneth cells: 67.5;Proximal enterocytes: 62.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 153.2;CACO-2: 50.1;CAPAN-2: 27.3;OE19: 48.0;RT4: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041459, HPA058230" Uncertain Supported "Cell Junctions,Centrosome" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Centrosome "HPA041459: AB_10794518, HPA058230: AB_2683645" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" "unprognostic (1.44e-1)" "unprognostic (8.03e-3)" "unprognostic (5.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.20e-2)" "unprognostic (1.22e-1)" "unprognostic (3.13e-1)" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (6.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (4.18e-2)" "unprognostic (5.73e-2)" 15.1 0.3 1.3 4.3 1.2 2.7 12.8 1.5 2.0 7.5 2.1 31.0 36.5 0.5 0.5 33.9 1.0 5.0 0.3 1.0 0.9 2.7 4.5 1.3 0.6 1.4 1.4 0.2 5.6 7.9 5.2 8.5 1.0 3.0 17.9 0.2 13.3 1.3 0.4 12.1 43.4 1.1 0.7 0.5 11.0 0.8 1.3 0.7 3.9 0.2 2.5 15.7 15.0 1.5 0.7 6.0 0.8 0.1 2.9 0.2 153.2 0.3 0.0 0.4 0.3 50.1 27.3 0.3 0.4 0.0 0.2 13.0 0.0 0.4 0.2 0.1 0.1 0.2 1.5 10.2 0.5 0.5 0.4 0.0 0.7 0.2 0.0 0.5 0.1 0.2 0.4 0.3 0.0 7.9 0.0 0.7 12.7 48.0 1.0 0.2 0.2 0.3 0.1 53.2 0.3 0.2 1.2 23.1 0.3 10.9 7.5 0.0 1.2 0.2 0.5 0.6 0.2 0.0 0.1 0.1 0.8 0.7 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 1.3 1.2 1.5 2.0 1.0 0.9 1.4 1.4 1.0 0.7 1.3 1.5 0.6 0.0 0.0 0.0 0.2 5.0 7.0 2.8 20.5 0.0 4.6 2.9 0.4 8.6 2.5 1.8 0.0 17.6 0.4 117.9 0.0 12.1 1.4 2.9 1.1 0.8 8.4 0.0 0.2 1.8 56.2 1.5 16.3 4.2 0.0 0.5 0.4 2.3 2.7 0.0 0.2 19.3 0.0 0.0 0.7 2.0 2.5 0.3 0.0 0.0 0.2 0.8 2.1 0.0 0.1 2.2 67.5 0.7 0.2 8.4 62.6 0.8 3.0 0.1 0.0 4.7 3.1 0.2 0.5 14.2 7.0 23.9 0.3 0.0 27.9 21.6 PLIN1 PLIN ENSG00000166819 "Perilipin 1" O60240 15 89664367-89679427 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "adipose tissue: 956.3;breast: 463.0" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 59.0" "Group enriched" "Detected in many" 5 "breast cancer: 8.4;liver cancer: 2.3;pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 171 "ASC diff: 208.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024299, CAB033821, CAB037333" Enhanced Uncertain Peroxisomes NA NA 22000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Peroxisomes "CAB033821: AB_2252681, CAB037333: , HPA024299: AB_1855467" "unprognostic (4.62e-2)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-1)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (9.89e-3)" "unprognostic (3.54e-1)" "unprognostic (7.01e-2)" "unprognostic (2.13e-2)" "unprognostic (8.00e-3)" "unprognostic (2.28e-3)" "unprognostic (2.62e-6)" "unprognostic (5.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "unprognostic (4.85e-2)" 956.3 11.3 12.0 3.5 14.8 0.3 463.0 7.4 10.6 1.4 5.3 9.3 0.5 0.7 0.4 1.3 1.4 6.6 10.4 10.0 10.3 2.7 40.8 0.7 1.7 6.9 11.5 2.1 6.1 0.2 1.3 0.2 7.8 2.6 3.7 0.6 20.8 0.6 9.5 16.0 13.9 1.5 6.6 1.0 5.5 13.2 10.6 2.3 5.3 17.3 0.1 7.9 3.1 8.2 0.0 0.2 0.2 0.0 208.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.7 0.5 0.1 0.7 0.2 0.0 0.2 0.6 0.7 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.3 1.2 0.1 0.5 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.4 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 14.8 7.4 10.6 10.0 10.3 6.9 11.5 7.8 6.6 10.6 8.2 2.6 0.0 0.0 4.2 0.2 0.1 0.3 0.1 0.0 0.3 0.7 3.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 7.5 0.1 0.2 0.2 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.2 0.0 0.1 1.1 59.0 0.0 0.0 0.3 0.3 0.0 1.0 0.3 7.5 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.2 1.3 0.0 0.0 0.6 0.3 0.1 0.1 0.1 0.0 1.3 1.3 4.8 0.2 0.0 0.4 0.0 0.1 0.1 0.5 0.9 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 202.0;skeletal muscle: 149.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.1;Astrocytes: 53.8;Cardiomyocytes: 39.8;Hepatic stellate cells: 42.1;Hepatocytes: 140.5" "Cancer enhanced" "Detected in many" "liver cancer: 9.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.9" "Cell line enhanced" "Detected in some" "AN3-CA: 2.3;BEWO: 3.2;RT4: 3.1;SH-SY5Y: 2.8;T-47d: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Lipid droplets" "HPA077050: " "prognostic favorable (7.68e-4)" "unprognostic (1.01e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-2)" "unprognostic (6.06e-3)" "prognostic favorable (2.81e-4)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (1.97e-4)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "prognostic favorable (2.16e-4)" 41.9 6.4 10.8 3.5 11.2 5.2 29.3 6.9 9.6 7.5 12.8 5.4 1.5 2.7 3.9 3.4 12.6 2.0 62.7 8.5 8.1 30.1 202.0 9.3 0.5 8.4 9.2 90.8 112.2 1.5 18.9 0.2 6.9 17.6 0.6 0.9 61.0 3.9 149.2 8.0 5.3 0.5 6.8 8.2 58.9 3.3 9.4 0.4 9.8 24.7 1.0 11.2 2.7 6.4 0.2 0.1 0.5 2.3 1.7 0.1 3.2 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.8 1.1 0.4 0.3 0.4 0.4 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.1 0.6 0.1 0.4 0.4 0.3 0.3 0.1 0.1 2.1 0.2 3.1 0.3 2.8 0.2 0.4 0.0 0.2 6.3 0.4 0.3 0.3 0.3 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.1 1.9 0.4 0.8 0.3 0.3 0.2 0.3 0.2 0.2 0.1 0.4 0.3 0.3 13.9 0.6 0.3 0.3 0.1 0.1 10.8 11.2 6.9 9.6 8.5 8.1 8.4 9.2 6.9 6.8 9.4 6.4 6.0 9.6 47.1 53.8 1.6 0.5 18.4 2.3 4.0 1.2 9.2 1.9 39.8 35.8 11.5 1.8 0.0 0.4 0.1 11.9 9.8 8.7 1.5 20.8 1.4 7.4 0.0 2.7 1.1 12.3 0.5 1.3 16.3 5.1 3.8 18.7 42.1 140.5 0.5 0.0 1.8 6.9 4.1 6.9 0.5 0.3 0.3 2.5 0.0 5.6 0.1 8.1 0.0 11.1 2.0 4.8 1.3 2.6 0.5 6.6 0.5 11.1 10.4 1.2 13.1 25.8 1.8 6.2 6.6 0.5 1.0 1.4 1.1 20.5 8.8 11.5 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 130.9;Basal respiratory cells: 115.1;Distal enterocytes: 143.7;Extravillous trophoblasts: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBF TERT88: 636.0;hTERT-RPE1: 723.8;U-87 MG: 566.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" NA NA 21000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 63.1 20.1 13.4 35.6 14.5 1.1 18.6 15.1 17.2 10.2 19.4 36.2 42.2 23.5 13.4 18.2 11.4 41.5 22.1 13.3 15.1 26.1 57.3 12.9 3.8 23.1 18.1 20.5 18.7 16.5 7.9 80.6 16.3 13.2 29.9 56.6 9.5 16.2 3.0 3.9 35.0 46.8 17.8 5.4 20.1 8.5 20.6 10.5 90.0 3.9 5.5 25.7 10.0 17.6 134.5 94.3 29.0 9.5 102.5 109.6 73.2 465.5 141.6 247.7 463.0 7.2 13.4 0.0 88.8 79.5 113.1 27.8 34.0 400.5 636.0 0.6 53.5 33.3 84.3 66.9 262.5 0.1 0.6 192.9 56.5 215.2 104.1 723.8 347.7 0.1 45.1 1.8 441.6 48.8 0.3 0.6 18.5 0.3 40.0 0.2 19.2 0.6 105.0 6.5 14.5 0.5 370.3 39.4 39.9 135.1 107.5 4.2 440.4 304.2 92.2 97.8 280.7 138.9 20.9 0.5 566.5 0.4 55.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 13.4 14.5 15.1 17.2 13.3 15.1 23.1 18.1 16.3 17.8 20.6 17.6 29.1 16.0 11.4 130.9 0.4 7.0 6.4 115.1 30.1 17.1 23.7 10.2 14.3 44.3 47.0 27.6 35.5 9.2 0.3 143.7 9.8 64.5 0.5 35.4 13.8 24.3 19.8 4.6 22.8 53.1 130.6 68.1 19.9 38.7 0.0 42.7 21.0 65.2 5.1 0.0 46.4 19.5 22.4 1.0 2.5 1.2 13.1 3.0 14.2 21.5 0.7 53.8 0.0 64.3 6.0 82.4 48.8 4.9 1.3 8.9 50.5 8.2 33.0 24.7 19.7 36.9 47.2 11.0 18.0 27.5 5.5 18.7 1.0 24.5 25.1 5.6 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 359.1;Endometrial stromal cells: 206.7;Hepatic stellate cells: 267.0;Leydig cells: 219.3;Prostatic glandular cells: 182.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 445.7;fHDF/TERT166: 142.8;HMC-1: 235.8;HSkMC: 171.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 172.3 78.1 51.5 42.3 59.9 0.9 140.7 63.7 59.4 88.7 59.6 118.3 47.4 119.5 39.8 42.4 73.4 167.5 117.1 49.9 56.8 104.0 67.7 56.2 32.2 62.1 56.2 29.4 35.6 49.0 27.8 37.6 64.2 254.1 65.8 9.7 32.9 61.3 70.0 57.9 79.1 108.9 62.5 31.1 70.9 21.0 58.6 15.8 112.9 81.5 24.2 128.8 63.8 72.9 9.8 24.4 7.0 14.2 445.7 51.8 9.6 21.8 61.4 11.9 27.9 16.7 17.7 10.2 20.0 142.8 31.9 6.5 25.2 12.6 13.5 6.8 20.1 1.1 9.6 21.3 70.5 2.5 235.8 171.3 25.7 17.6 10.9 23.3 19.9 9.1 0.2 27.0 24.1 6.0 6.8 5.5 15.5 1.1 20.0 2.0 11.7 0.9 46.3 79.8 8.4 5.8 21.5 4.2 13.4 28.8 15.6 1.6 24.0 4.0 6.9 17.8 15.5 16.6 7.4 11.8 15.7 1.3 19.5 0.0 0.4 4.0 1.6 0.5 1.7 6.7 5.3 3.4 2.0 3.3 9.5 7.7 0.3 3.0 0.9 15.0 2.6 1.8 51.5 59.9 63.7 59.4 49.9 56.8 62.1 56.2 64.2 62.5 58.6 72.9 359.1 6.4 9.4 0.0 9.8 0.0 51.0 0.0 10.2 4.0 8.4 45.7 0.0 21.5 5.6 29.5 2.1 3.3 5.4 61.0 5.9 25.2 44.4 10.7 206.7 112.3 1.2 5.7 0.0 28.5 11.1 115.5 11.2 18.5 27.8 4.0 267.0 48.3 12.8 1.7 0.0 20.2 0.0 12.0 0.0 21.0 219.3 8.1 0.0 0.0 4.5 16.6 1.0 0.0 0.0 30.0 24.6 88.4 13.0 182.0 49.4 29.3 2.2 5.6 59.2 89.7 49.7 54.4 17.7 10.0 0.0 4.9 11.3 3.1 12.1 42.8 PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821955 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 9.8;brain: 21.1;fallopian tube: 11.1" "Cell type enriched" "Detected in some" 7 "Endometrial ciliated cells: 37.2" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NB-4: 61.8;THP-1: 128.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: AB_2681787, HPA057034: AB_2683316" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" 0.0 0.0 16.8 0.2 14.1 9.8 2.2 0.0 21.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 11.1 0.1 0.1 14.2 11.5 0.0 0.0 2.3 0.1 4.1 8.2 0.3 0.0 0.2 0.4 0.0 1.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 2.3 0.2 0.1 3.2 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.5 12.2 0.0 0.0 0.0 6.9 0.2 0.1 0.0 0.0 0.7 0.1 0.1 8.4 0.1 0.1 0.3 2.3 0.0 0.0 0.0 5.2 0.0 1.6 0.0 0.5 4.4 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 12.0 0.3 0.0 1.1 0.0 61.8 9.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 15.5 0.3 0.0 0.0 6.3 5.4 128.9 0.1 0.2 0.2 0.3 0.1 0.2 0.5 0.2 0.0 10.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 14.1 0.0 21.1 14.2 11.5 4.1 8.2 1.5 2.3 13.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 37.2 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.4 0.0 1.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 0.1 5.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 77.3;Astrocytes: 151.1;Endothelial cells: 63.4;Hepatic stellate cells: 110.3;Oligodendrocyte precursor cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.5;ASC TERT1: 48.2;hTERT-RPE1: 62.1;HUVEC TERT2: 50.8;TIME: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA002276: AB_1855479" "unprognostic (3.73e-3)" "unprognostic (4.03e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.62e-1)" "unprognostic (6.77e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-4)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.97e-3)" 60.2 43.8 30.2 9.4 28.2 2.3 41.9 30.9 32.5 28.9 11.6 27.4 6.8 30.1 15.7 23.2 41.2 45.6 28.0 28.7 38.5 25.3 69.0 37.4 10.5 39.3 44.0 36.4 20.5 4.3 11.2 56.4 32.6 13.8 25.2 13.7 23.6 25.8 7.4 16.1 13.6 33.7 36.9 30.1 14.4 21.6 41.8 6.6 31.2 18.8 6.7 19.8 25.5 32.2 0.0 9.9 1.7 0.0 60.5 48.2 0.3 11.5 15.7 5.0 10.9 1.0 12.6 0.0 12.3 21.0 5.0 1.4 2.4 1.1 2.8 0.1 0.1 5.0 7.9 1.3 28.1 0.1 1.3 29.6 1.6 10.4 3.0 62.1 50.8 0.0 0.2 0.9 7.4 0.3 0.0 0.1 2.1 5.1 3.4 0.0 0.8 0.0 0.1 0.0 0.6 0.0 20.1 0.1 3.9 2.5 0.7 0.6 106.4 10.4 2.6 23.6 2.1 0.3 0.0 0.0 2.6 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 28.2 30.9 32.5 28.7 38.5 39.3 44.0 32.6 36.9 41.8 32.2 77.3 3.2 10.3 151.1 1.0 10.8 5.6 0.8 12.0 0.6 10.2 8.6 4.1 25.8 6.0 3.7 0.0 0.7 0.3 27.4 0.0 8.2 1.1 3.6 11.6 63.4 10.3 15.6 1.7 11.6 0.5 57.1 2.0 1.5 1.3 7.0 110.3 44.1 0.8 0.0 0.6 11.7 0.0 7.1 11.8 3.8 42.9 1.1 3.6 40.3 0.1 51.4 0.0 61.3 0.6 4.7 13.3 32.4 2.8 2.6 6.4 28.3 6.4 1.5 0.0 18.9 23.6 1.2 0.9 4.8 8.7 0.8 1.8 20.0 8.1 2.7 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1508.4;Oligodendrocytes: 470.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Cell line enhanced" "Detected in some" "HHSteC: 19.4;U-2197: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" 12.4 9.4 13.3 7.3 14.1 5.2 11.5 9.6 13.3 12.7 16.8 5.3 4.2 10.7 3.5 7.5 10.1 17.4 10.2 11.3 25.6 10.7 3.1 17.1 2.4 18.0 17.3 9.4 3.6 16.2 3.3 4.7 19.2 7.6 4.6 18.2 6.2 7.7 5.0 15.5 7.1 16.2 16.2 9.4 3.8 5.9 22.3 2.5 6.8 10.0 2.8 8.5 8.9 29.1 0.0 0.0 5.8 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 7.7 2.2 1.8 0.0 0.0 0.7 2.8 8.6 0.4 19.4 0.0 0.0 7.7 0.6 0.0 2.3 8.9 0.0 0.0 0.1 1.7 0.9 1.1 0.6 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 0.2 2.4 0.4 0.0 1.8 0.8 0.9 0.0 7.6 3.9 45.9 0.0 0.1 0.0 0.0 3.5 0.1 0.0 10.7 57.5 11.8 1.3 33.4 2.7 0.0 0.0 0.3 36.0 0.0 0.0 0.0 81.6 4.4 37.3 1.6 0.0 17.7 13.3 14.1 9.6 13.3 11.3 25.6 18.0 17.3 19.2 16.2 22.3 29.1 101.4 16.0 8.9 131.9 2.6 36.8 23.8 12.3 41.5 44.2 14.4 45.3 10.9 15.7 10.9 5.5 8.4 0.9 2.9 7.1 0.0 6.9 2.9 16.5 7.6 45.3 3.0 10.5 190.9 0.0 8.1 97.2 1.1 19.4 31.6 80.9 82.1 4.2 94.3 1.7 59.9 27.3 8.2 91.3 46.3 2.1 19.3 147.7 7.2 1508.4 94.5 25.5 5.2 158.3 470.2 1.0 16.6 57.2 3.8 5.5 16.0 22.2 3.0 73.6 19.7 110.1 12.7 1.6 1.2 35.5 38.1 1.2 4.2 71.4 8.8 11.7 PLXNA2 "FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2" ENSG00000076356 "Plexin A2" O75051 1 208022242-208244384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 35.1" "Cell type enhanced" "Detected in many" "Astrocytes: 100.6;Excitatory neurons: 134.7;Horizontal cells: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 52.8;HaCaT: 55.4;HUVEC TERT2: 70.3;TIME: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009763 Approved NA NA 1400000 "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB009763: AB_2166388" "unprognostic (8.25e-2)" "unprognostic (3.91e-2)" "unprognostic (8.85e-2)" "unprognostic (2.77e-2)" "unprognostic (8.66e-2)" "unprognostic (2.07e-1)" "unprognostic (1.97e-2)" "unprognostic (4.84e-2)" "unprognostic (6.88e-3)" "unprognostic (7.06e-2)" "unprognostic (2.61e-1)" "unprognostic (8.41e-2)" "unprognostic (4.49e-3)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (1.27e-2)" "unprognostic (2.40e-1)" 7.9 1.4 6.6 2.1 9.1 0.4 4.9 10.5 11.2 3.9 19.0 9.0 6.8 6.0 2.0 15.4 5.2 4.0 8.8 10.0 1.6 3.4 2.4 14.3 1.0 2.2 7.8 13.8 35.1 1.3 3.0 8.5 3.2 4.1 7.2 3.7 4.1 3.1 9.6 9.5 7.7 5.9 4.5 1.3 9.0 0.6 2.7 4.3 6.8 9.4 2.4 9.4 6.3 7.7 6.4 3.7 6.9 1.0 7.6 14.7 52.8 5.0 3.1 3.0 0.5 0.2 0.1 0.0 9.8 3.9 1.3 55.4 0.1 31.4 0.9 1.9 1.1 0.0 6.9 3.7 3.2 0.0 0.2 3.9 10.0 2.4 14.2 2.0 70.3 0.0 0.0 0.0 30.7 0.7 0.1 0.1 1.1 11.2 9.4 0.0 7.0 4.7 5.7 4.0 2.0 12.5 5.9 4.5 5.5 13.3 0.5 0.0 162.9 1.1 1.7 5.9 10.4 0.3 0.0 0.0 6.5 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 9.1 10.5 11.2 10.0 1.6 2.2 7.8 3.2 4.5 2.7 7.7 50.7 28.9 28.6 100.6 1.7 4.8 16.2 12.9 30.1 12.7 2.9 2.2 5.8 7.2 25.6 0.0 2.1 5.3 0.8 64.6 1.9 4.2 0.9 13.8 0.9 48.1 9.1 0.0 134.7 15.3 2.5 9.6 44.4 9.5 6.3 1.1 36.8 5.9 3.3 249.0 62.9 29.0 8.2 5.5 6.0 0.6 9.9 4.4 5.4 54.4 1.4 0.4 1.0 44.7 3.1 23.3 52.2 6.8 1.7 8.2 33.6 2.2 8.5 2.7 6.6 26.3 8.1 1.9 1.0 41.1 10.5 1.9 1.1 1.4 26.5 22.7 PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123332-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.8;brain: 29.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 235.3;Inhibitory neurons: 261.3" "Cancer enhanced" "Detected in many" "glioma: 3.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 29.1;hippocampal formation: 26.0" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cell line enhanced" "Detected in some" "ASC diff: 25.2;HMC-1: 17.1;hTERT-RPE1: 22.1;RH-30: 18.5;TIME: 57.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029919: AB_10671093, HPA052141: AB_2681745, HPA075592: AB_2732297" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.61e-6)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.19e-1)" "unprognostic (7.99e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-5)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (5.90e-2)" "unprognostic (1.42e-3)" 13.8 2.4 4.2 1.6 5.6 0.3 7.6 0.1 29.1 8.4 0.0 1.5 0.4 1.5 0.2 3.8 2.0 1.9 3.9 26.0 1.3 0.7 0.3 1.2 1.0 2.3 0.1 3.6 0.4 0.1 1.0 3.5 1.8 0.5 0.7 4.8 0.4 0.9 0.7 2.2 0.8 2.6 0.9 1.5 1.6 1.1 1.6 0.2 1.5 3.1 0.3 1.0 0.7 4.4 0.0 0.1 0.2 0.0 25.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 17.1 0.2 0.0 0.1 0.0 22.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 18.5 2.0 0.0 0.0 0.4 9.6 0.0 0.0 0.0 0.2 0.0 0.0 57.6 5.7 0.2 1.3 0.5 0.0 0.0 0.0 5.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.6 0.0 0.0 4.2 5.6 0.1 29.1 26.0 1.3 2.3 0.1 1.8 0.9 1.6 4.4 2.5 0.0 0.0 5.2 0.6 0.6 0.2 0.0 0.0 22.4 2.2 0.1 10.9 0.0 0.0 12.9 16.7 0.1 17.4 0.0 0.0 0.0 14.0 2.1 3.0 2.7 1.2 0.0 235.3 0.0 0.1 7.4 1.1 5.0 1.3 1.6 5.0 0.2 0.1 0.0 261.3 0.1 0.0 0.0 1.1 9.8 14.0 0.7 7.2 10.3 0.0 11.3 2.1 51.8 3.7 0.8 0.0 7.2 0.7 0.1 0.0 0.5 0.0 1.5 0.0 0.7 1.1 0.2 0.3 0.1 1.3 0.0 1.7 0.4 0.1 0.4 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 PML "MYL, RNF71, TRIM19" ENSG00000140464 "PML nuclear body scaffold" P29590 15 73994673-74047827 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Biological rhythms, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008312, CAB010194, CAB016304" Supported Enhanced "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear bodies" "CAB010194: AB_2166848, CAB016304: AB_628162, HPA008312: AB_1079643" "prognostic favorable (3.24e-4)" "unprognostic (4.83e-2)" "unprognostic (5.76e-2)" "unprognostic (1.58e-3)" "unprognostic (7.53e-3)" "unprognostic (1.58e-1)" "unprognostic (2.35e-2)" "unprognostic (5.30e-3)" "unprognostic (4.54e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.29e-4)" "unprognostic (2.67e-2)" "prognostic unfavorable (6.27e-8)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.99e-2)" 84.4 29.4 14.4 25.6 13.8 38.1 77.0 11.8 16.4 53.7 11.6 46.7 18.4 47.1 7.5 38.3 44.6 21.6 39.3 13.8 13.1 35.4 25.4 75.2 25.6 18.2 13.8 37.5 20.3 8.3 26.8 23.7 14.8 41.5 8.5 3.9 44.2 17.2 22.5 47.4 39.0 19.5 14.6 48.6 35.3 11.3 15.2 17.0 48.1 7.9 15.2 42.7 44.5 13.1 37.2 13.8 11.8 11.4 30.2 43.2 40.6 18.5 31.6 55.9 63.3 14.6 64.2 16.4 63.7 31.6 53.3 66.6 16.3 37.1 7.6 58.0 25.1 35.8 21.3 16.3 36.9 33.9 31.1 83.7 24.8 37.5 19.2 39.3 38.3 26.1 30.6 28.3 32.7 17.3 28.3 52.6 12.8 7.7 25.0 21.6 13.4 30.8 60.3 59.5 10.1 11.1 29.7 16.3 44.8 10.3 12.8 28.7 66.1 56.6 15.5 28.5 38.1 29.4 20.0 8.0 38.9 42.2 18.2 7.4 14.7 23.4 13.0 20.2 9.8 12.4 10.4 14.1 14.5 10.2 8.2 8.5 12.0 14.5 22.6 9.2 14.3 10.1 14.4 13.8 11.8 16.4 13.8 13.1 18.2 13.8 14.8 14.6 15.2 13.1 127.8 16.0 12.2 8.8 24.9 22.9 14.3 30.4 37.5 8.1 13.5 12.8 10.0 5.7 16.7 5.5 2.1 9.4 18.8 13.1 7.9 25.8 3.4 16.0 16.7 48.0 14.3 29.3 4.7 19.1 15.0 20.7 58.1 26.0 12.0 11.5 32.2 11.3 30.8 8.4 4.8 14.3 14.2 20.1 18.5 4.0 27.7 19.6 7.2 7.5 24.6 8.5 20.6 4.5 6.0 62.8 15.5 24.0 21.6 26.2 22.8 10.4 18.3 5.4 39.5 7.7 20.4 1.1 4.0 27.1 19.6 4.9 20.4 16.8 12.1 26.0 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 47.0 51.7 49.0 12.0 50.4 26.2 39.0 47.0 65.0 34.4 41.2 33.6 37.7 26.9 19.2 73.7 34.7 18.8 26.5 49.5 52.1 59.4 64.2 33.8 17.5 46.9 47.2 48.1 45.0 15.4 19.5 14.2 51.2 26.5 20.3 13.6 23.3 20.2 16.2 33.2 33.8 19.9 47.8 13.7 65.7 32.6 49.8 14.3 13.8 11.4 16.8 31.7 28.0 49.7 16.0 29.0 19.6 42.5 54.3 84.0 23.0 61.7 69.8 56.0 61.0 23.0 15.3 14.9 20.3 74.4 40.0 23.4 25.8 40.0 31.1 31.2 38.6 3.8 34.8 49.2 85.8 22.6 23.8 70.4 38.2 58.3 24.2 61.9 9.3 23.8 16.9 51.9 76.5 42.0 17.1 32.5 6.2 75.1 38.2 13.1 20.7 30.7 24.0 17.1 5.8 11.2 50.5 18.1 75.2 15.2 20.3 24.4 7.5 63.2 34.3 59.4 32.8 33.2 34.0 24.3 70.3 18.8 38.7 21.0 22.0 44.8 27.7 18.5 22.3 17.8 27.6 22.8 23.2 20.5 29.4 21.1 28.8 13.4 22.9 9.2 49.4 18.8 49.0 50.4 47.0 65.0 49.5 52.1 46.9 47.2 51.2 47.8 49.8 49.7 7.8 35.3 106.4 16.3 15.0 14.8 10.2 22.5 20.5 16.7 22.8 29.3 12.4 82.9 25.8 35.0 6.2 57.1 10.0 104.8 107.6 31.8 17.1 77.7 34.2 6.9 48.7 19.3 14.9 11.0 91.1 33.3 36.2 51.4 3.8 60.9 8.9 83.5 34.5 28.6 10.9 58.1 14.2 14.4 13.5 15.3 28.0 16.3 44.4 3.7 21.9 67.1 16.5 4.0 7.1 10.8 117.0 30.5 17.7 8.5 176.1 138.5 34.8 22.6 39.5 18.9 36.9 72.6 10.9 23.1 14.1 65.3 21.0 37.9 55.3 8.2 PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;fallopian tube: 18.2;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 61.5;dendritic cells: 12.6;Inhibitory neurons: 23.3;Melanocytes: 14.2;Plasma cells: 80.4" "Cancer enriched" "Detected in many" 8 "ovarian cancer: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 231.2;naive B-cell: 260.3;plasmacytoid DC: 194.0" "Group enriched" "Detected in many" 20 "B-cells: 260.3;dendritic cells: 194.0" "Group enriched" "Detected in some" 6 "Daudi: 38.3;Karpas-707: 29.2;RPMI-8226: 11.2;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced "Secreted to blood" NA NA 12300 "Cluster 19: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA044507: AB_10795043, HPA056724: AB_2683216" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.94e-6)" "unprognostic (3.71e-2)" "unprognostic (5.16e-5)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (7.81e-4)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" "unprognostic (7.57e-9)" "unprognostic (2.19e-2)" "unprognostic (5.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-1)" 0.2 0.8 5.4 9.9 5.1 2.7 0.6 1.3 10.8 0.2 1.3 2.9 4.3 0.1 0.0 0.6 18.2 1.1 0.1 2.9 9.9 0.7 0.2 1.0 25.1 10.4 6.3 0.4 0.0 0.0 0.0 0.0 9.9 0.2 1.5 0.0 1.6 0.1 0.0 0.1 5.8 0.5 14.3 14.4 3.2 0.6 4.3 2.7 0.4 0.0 23.6 3.7 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 4.0 4.4 23.0 0.1 0.1 0.0 0.2 11.5 2.3 0.2 7.7 0.1 231.2 0.2 0.1 1.1 260.3 0.1 0.1 1.3 1.2 3.2 194.0 0.5 11.1 5.4 5.1 1.3 10.8 2.9 9.9 10.4 6.3 9.9 14.3 4.3 3.0 0.1 0.0 1.9 1.3 61.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.4 0.4 0.2 0.0 23.3 0.1 0.0 0.0 0.3 2.8 0.3 1.7 14.2 1.0 3.0 0.0 1.0 0.0 0.9 0.1 0.0 0.0 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 1.1 0.0 0.3 0.5 PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818914-825573 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 508.1;breast: 361.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "HPA055173: AB_2682725, HPA062602: AB_2684804, HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" 508.1 75.3 11.9 9.2 14.0 43.1 361.4 13.6 18.8 42.2 13.4 58.1 19.3 49.2 2.8 39.9 50.8 9.5 171.3 11.9 14.0 61.9 58.4 57.3 8.1 17.5 11.8 50.5 75.4 9.6 46.3 8.4 16.8 46.6 4.8 1.3 81.1 16.7 194.6 71.8 74.7 6.4 12.6 51.2 71.3 32.1 12.8 10.9 55.3 64.3 4.1 64.8 44.5 15.3 33.9 26.0 5.3 14.0 194.4 17.2 34.1 35.3 28.1 21.6 19.1 22.3 33.3 19.9 20.4 26.7 13.6 30.0 8.1 14.6 6.6 25.9 71.5 27.6 11.2 36.3 63.3 19.2 33.4 33.9 18.7 14.5 16.7 22.3 17.7 14.5 23.8 19.9 19.5 20.0 25.8 42.3 15.2 34.3 55.1 24.6 11.5 45.7 21.4 7.7 19.6 26.0 65.3 55.0 21.9 3.4 23.7 22.0 32.5 19.3 15.0 12.7 16.3 75.2 49.8 16.7 48.4 27.0 13.8 11.5 9.5 22.1 3.7 6.1 3.6 4.7 4.8 5.4 6.1 4.1 5.4 4.4 8.2 4.0 7.1 7.0 4.2 4.7 11.9 14.0 13.6 18.8 11.9 14.0 17.5 11.8 16.8 12.6 12.8 15.3 78.1 6.4 11.8 12.7 63.5 44.2 69.2 34.2 42.1 14.0 79.5 67.1 45.5 61.5 65.2 51.5 8.4 70.2 50.8 151.8 33.2 65.1 22.1 58.0 31.8 51.8 51.5 52.6 8.9 65.3 32.0 37.4 204.4 114.3 11.4 42.2 100.6 50.6 29.2 11.8 7.5 96.1 20.3 27.6 29.0 6.2 48.4 46.6 42.7 16.9 29.6 32.2 21.6 5.5 13.8 142.2 170.7 39.1 92.0 78.5 166.8 45.0 31.3 9.0 65.7 64.4 50.7 33.5 23.9 53.7 41.2 169.4 53.3 182.2 43.6 195.5 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207880-32238658 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 20.9" "Lineage enriched" "Detected in all" 5 "monocytes: 20.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" NA NA 60000 "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "HPA054519: AB_2682515, HPA059935: AB_2684171" "unprognostic (6.61e-2)" "unprognostic (4.10e-3)" "unprognostic (8.83e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (1.62e-1)" "unprognostic (4.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (5.86e-3)" 17.6 10.8 7.9 11.7 8.4 10.5 16.5 7.2 7.7 15.2 9.1 20.0 20.4 14.9 14.4 12.4 20.4 11.4 17.5 7.7 7.3 16.1 30.9 12.2 9.1 9.3 8.3 20.0 13.8 23.8 9.1 16.4 8.0 14.5 19.1 5.9 13.0 18.1 12.8 13.7 24.0 18.1 8.0 9.4 11.1 9.5 8.1 10.5 18.9 14.0 10.0 14.0 10.9 8.2 47.1 37.2 31.5 34.7 52.9 51.4 58.8 47.8 56.2 78.8 51.3 111.9 62.1 31.7 69.8 53.5 87.2 51.2 30.5 59.0 68.0 16.5 19.2 47.1 32.1 51.2 41.2 41.0 28.9 45.4 45.7 59.7 38.8 33.5 44.6 30.0 36.3 17.6 55.6 23.1 28.4 31.4 16.2 45.2 59.4 23.3 83.6 29.5 24.2 30.7 20.6 26.5 109.5 30.0 41.0 24.0 44.7 48.5 38.8 113.4 42.2 71.8 82.4 21.4 29.3 28.7 68.5 139.9 73.0 4.3 5.4 2.6 3.2 15.1 3.6 3.2 2.8 3.0 4.6 2.6 3.6 2.5 1.0 2.0 20.9 3.4 3.3 4.2 7.9 8.4 7.2 7.7 7.7 7.3 9.3 8.3 8.0 8.0 8.1 8.2 7.8 9.6 9.5 11.1 5.2 2.9 4.7 8.6 5.2 3.1 7.2 7.1 13.4 8.6 7.9 7.3 2.1 15.2 5.7 17.5 1.9 10.0 0.9 7.1 10.8 9.3 12.0 9.2 9.0 10.4 28.2 12.0 9.2 13.6 5.1 13.1 13.9 39.8 10.7 8.4 9.0 13.4 2.0 8.1 3.8 1.7 10.5 6.5 5.4 6.5 9.3 5.2 3.1 11.1 9.6 9.6 11.9 14.3 8.2 6.7 31.7 5.3 7.2 4.3 13.1 11.1 9.4 2.9 7.3 9.7 1.7 7.7 5.0 26.0 19.0 4.1 POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Cardiomyocytes: 13.1;Cytotrophoblasts: 27.6;Extravillous trophoblasts: 14.5;Fibroblasts: 14.7;Hofbauer cells: 18.0;Syncytiotrophoblasts: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" 24.6 13.2 5.0 17.3 5.0 7.6 16.2 4.6 5.4 33.6 7.0 16.8 9.4 35.0 27.3 21.0 23.0 21.7 15.2 4.2 5.9 15.6 13.2 16.0 10.4 5.5 6.1 36.5 8.3 25.2 5.4 32.7 5.4 28.4 16.9 5.8 13.9 28.4 5.5 13.7 11.2 37.1 5.3 12.4 11.3 5.8 5.5 16.4 12.1 13.9 9.5 22.5 18.8 6.0 10.9 12.4 46.5 47.8 76.5 88.5 44.8 47.0 43.7 66.0 71.1 58.9 78.1 0.1 28.6 61.6 73.1 7.9 35.6 1.2 69.3 19.4 27.4 18.1 12.1 27.2 30.8 47.7 0.2 51.1 14.6 35.0 1.0 40.1 56.6 0.3 41.5 0.3 101.0 7.9 30.9 27.2 20.3 11.5 34.8 1.5 72.5 0.2 12.3 30.3 9.7 29.5 89.1 6.2 13.3 21.4 42.3 18.0 56.8 127.0 24.9 10.8 49.7 0.4 0.1 0.3 32.6 48.9 103.1 0.1 0.1 0.0 2.0 0.7 1.7 0.2 1.0 1.7 0.5 0.3 1.0 1.5 0.1 1.9 0.4 1.0 0.9 0.5 5.0 5.0 4.6 5.4 4.2 5.9 5.5 6.1 5.4 5.3 5.5 6.0 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 27.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 14.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 21.2 0.5 0.0 0.0 0.0 POLN ENSG00000130997 "DNA polymerase nu" Q7Z5Q5 4 2071918-2242121 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.4;testis: 2.6" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Excitatory neurons: 77.7;Inhibitory neurons: 42.7;Oligodendrocyte precursor cells: 22.1;Oligodendrocytes: 26.8;Spermatocytes: 23.4" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035939, HPA035940" Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA035939: AB_2674875, HPA035940: AB_2674876" "unprognostic (8.52e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.45e-2)" "unprognostic (3.46e-1)" "unprognostic (2.70e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-3)" "unprognostic (1.25e-1)" "unprognostic (1.49e-3)" "unprognostic (9.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" 2.4 0.6 0.3 0.0 0.4 0.0 1.0 0.2 0.5 0.3 0.0 0.3 0.1 0.3 0.7 0.1 0.4 0.3 0.3 0.3 0.0 0.4 0.4 0.2 0.2 0.0 0.0 0.2 0.4 0.1 0.4 0.1 0.0 0.6 0.0 0.2 0.5 0.2 0.4 0.3 0.3 0.1 0.0 0.3 0.3 2.6 0.1 0.1 0.3 0.1 0.1 0.2 0.2 0.4 0.0 0.6 0.0 0.3 1.7 0.5 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.2 0.7 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 2.4 0.0 0.0 32.3 1.0 0.9 1.0 0.6 0.6 4.2 3.0 1.5 3.6 1.5 1.7 0.0 0.0 0.2 0.6 0.2 3.9 0.4 8.3 4.2 2.0 1.9 4.8 0.8 77.7 1.0 0.3 2.0 1.5 2.1 0.0 5.5 3.3 1.1 0.7 3.3 42.7 0.0 2.0 1.3 1.0 14.1 4.4 1.3 0.0 15.0 0.7 2.5 1.0 22.1 26.8 0.5 1.1 3.8 1.5 1.0 0.3 0.8 1.9 3.8 0.0 2.9 1.1 23.4 10.4 0.5 1.6 0.0 1.8 4.1 0.3 1.3 POLR2E "hRPB25, hsRPB5, RPABC1, RPB5, XAP4" ENSG00000099817 "RNA polymerase II, I and III subunit E" P19388 19 1086574-1095380 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Host-virus interaction, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063030, HPA068992" Supported Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA063030: AB_2684926, HPA068992: AB_2686065" "unprognostic (2.52e-1)" "unprognostic (3.73e-2)" "unprognostic (2.49e-1)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (6.42e-2)" "unprognostic (2.59e-3)" "unprognostic (1.60e-1)" "unprognostic (2.08e-1)" "unprognostic (2.05e-1)" "unprognostic (2.03e-3)" "unprognostic (3.03e-2)" "prognostic favorable (3.21e-6)" "unprognostic (3.22e-1)" "unprognostic (1.47e-1)" "unprognostic (1.72e-3)" "unprognostic (4.77e-2)" 30.8 16.7 25.5 16.3 22.9 15.4 18.1 23.0 28.9 13.0 16.0 18.7 13.7 12.8 14.4 22.8 17.3 7.9 14.6 25.9 23.5 23.6 41.1 17.0 18.6 28.1 24.7 14.0 13.2 20.3 12.2 10.3 28.6 12.5 19.5 17.5 14.8 12.1 16.4 16.2 17.0 16.7 23.4 19.3 15.9 13.0 26.6 13.8 17.0 22.6 26.6 14.0 11.2 24.1 33.6 30.8 41.6 33.4 55.6 34.5 19.5 24.2 34.1 39.5 23.1 36.1 11.9 27.5 10.7 72.1 6.1 26.5 79.1 26.9 73.1 29.2 23.9 36.3 36.2 33.9 22.3 54.3 26.4 25.5 17.5 27.7 51.0 40.6 36.7 14.7 42.3 31.0 44.3 27.6 30.0 17.1 33.6 23.9 23.1 31.9 40.7 27.0 39.5 38.3 21.0 23.9 40.2 27.8 17.5 37.2 29.5 24.7 49.9 19.6 21.7 36.0 28.4 47.6 70.9 50.9 32.3 34.6 23.2 24.2 50.2 29.5 25.5 33.7 26.5 18.2 23.2 26.0 44.3 19.6 18.5 18.4 25.2 28.7 38.7 31.2 24.5 38.4 25.5 22.9 23.0 28.9 25.9 23.5 28.1 24.7 28.6 23.4 26.6 24.1 67.7 32.1 63.0 8.1 80.1 104.3 83.9 152.1 59.7 55.7 80.9 82.9 78.2 60.1 79.9 55.2 41.7 234.3 67.4 103.1 174.1 156.7 21.0 64.0 64.4 77.8 70.6 77.4 13.0 141.1 264.1 95.1 66.3 57.2 71.0 74.9 68.9 96.6 259.7 55.5 13.9 91.8 107.8 93.6 221.7 37.8 69.3 103.7 99.6 6.5 361.7 78.1 103.0 4.5 10.6 162.5 84.6 62.1 93.8 111.7 163.1 188.4 72.3 48.9 26.3 50.5 96.9 125.4 82.5 104.1 109.7 234.6 73.4 110.6 130.5 106.9 POLR2L "hRPB7.6, hsRPB10b, RBP10, RPABC5, RPB10beta, RPB7.6" ENSG00000177700 "RNA polymerase II, I and III subunit L" P62875 11 837356-842529 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 1813.6;Proximal tubular cells: 1989.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 569.0;PC-3: 706.8" "Low region specificity" "Detected in all" HPA073614 Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA073614: " "unprognostic (2.65e-2)" "unprognostic (6.56e-3)" "unprognostic (1.40e-1)" "unprognostic (5.71e-2)" "unprognostic (3.49e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.37e-4)" "unprognostic (6.17e-3)" "unprognostic (1.34e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (6.77e-2)" "prognostic favorable (5.56e-4)" "unprognostic (3.60e-2)" "unprognostic (1.32e-1)" "unprognostic (4.03e-3)" "unprognostic (1.73e-1)" 112.1 101.2 68.2 21.5 69.9 27.2 91.0 69.0 98.3 48.0 90.5 63.5 26.1 48.9 16.5 87.1 43.3 16.4 161.8 72.9 75.3 112.7 107.6 68.3 20.4 68.3 71.0 37.3 111.5 30.4 71.7 21.1 70.1 67.9 15.4 11.9 62.6 31.3 101.0 65.3 46.2 24.9 67.9 68.4 63.3 34.3 70.1 21.0 72.5 43.1 17.6 63.3 54.1 69.7 106.4 569.0 52.9 66.5 150.1 107.8 45.6 134.5 94.1 129.6 86.5 166.2 97.6 64.4 35.6 166.6 110.4 69.5 79.7 160.8 39.9 59.9 381.6 63.4 160.7 216.6 88.3 62.3 49.3 178.9 71.6 74.2 36.6 79.2 101.7 63.9 67.0 71.3 156.1 268.4 59.7 63.1 82.6 124.7 706.8 58.8 41.9 99.3 160.7 81.1 104.1 32.1 133.3 135.2 107.3 28.2 81.2 36.7 117.9 87.5 69.1 48.3 83.8 40.0 50.0 62.3 130.8 58.3 78.2 93.3 119.5 121.7 92.9 109.0 100.1 75.5 86.0 92.0 114.0 73.6 71.8 89.3 32.1 123.7 76.6 141.1 92.5 134.7 68.2 69.9 69.0 98.3 72.9 75.3 68.3 71.0 70.1 67.9 70.1 69.7 364.4 410.3 390.2 9.8 265.9 611.8 245.0 767.6 279.4 68.1 491.1 412.0 500.6 584.8 415.4 526.0 25.0 625.4 305.0 669.3 1287.4 444.0 84.2 388.4 377.2 400.3 501.7 363.4 5.0 684.1 467.7 392.3 283.4 301.7 266.2 194.4 649.6 1813.6 700.2 50.5 5.3 641.6 323.5 434.5 582.0 235.7 305.7 307.3 658.1 11.2 493.6 368.5 389.3 3.5 9.0 751.1 589.2 255.1 382.8 300.0 813.6 1989.1 329.9 82.5 157.8 195.2 340.8 182.6 268.6 459.8 696.6 449.6 286.1 284.9 553.1 289.7 POPDC2 POP2 ENSG00000121577 "Popeye domain containing 2" Q9HBU9 3 119636457-119665324 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 405.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 272.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 10 "SH-SY5Y: 24.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA024255 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024255: AB_1855545" "unprognostic (1.13e-1)" "unprognostic (1.17e-3)" "unprognostic (8.91e-3)" "unprognostic (9.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.64e-2)" "unprognostic (2.73e-2)" "unprognostic (2.43e-1)" "unprognostic (3.18e-2)" "unprognostic (1.72e-2)" "unprognostic (5.86e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (6.26e-3)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-2)" 3.6 2.1 0.6 3.8 0.5 0.3 3.3 0.8 0.9 7.9 1.3 95.3 2.8 12.5 2.6 2.0 9.6 10.9 405.4 0.5 0.5 2.4 1.0 2.5 6.7 0.6 0.6 2.0 1.3 8.4 1.3 1.4 0.6 16.3 6.2 0.9 3.3 49.2 77.7 2.8 12.2 24.0 0.5 2.8 10.7 1.0 0.6 1.5 2.4 96.9 2.5 35.3 6.0 0.5 0.1 0.2 0.5 0.0 0.2 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.0 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.2 0.0 0.3 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.2 24.8 0.0 0.0 0.6 2.5 0.0 0.3 0.0 0.2 0.1 0.2 0.1 1.0 0.0 0.2 0.2 0.3 0.5 0.5 0.0 0.7 0.3 0.0 0.4 0.1 0.5 0.4 0.0 0.4 0.8 0.2 0.0 0.2 1.3 0.2 0.7 0.1 0.6 0.5 0.8 0.9 0.5 0.5 0.6 0.6 0.6 0.5 0.6 0.5 4.7 0.0 0.5 1.0 0.6 0.4 0.3 0.5 0.0 3.1 0.9 3.0 272.7 0.0 0.9 0.0 0.0 0.5 2.3 0.4 0.0 0.5 0.3 0.6 0.5 6.4 3.0 0.0 0.8 0.2 0.1 8.0 0.5 0.3 1.3 1.6 1.4 0.2 1.6 1.7 1.2 0.8 0.0 1.0 2.3 0.8 1.2 1.6 0.0 2.8 1.8 1.2 0.0 1.0 1.9 0.5 0.2 1.9 0.0 0.8 0.7 0.3 1.9 2.4 59.2 5.9 11.1 1.0 0.3 0.1 0.6 1.2 1.6 0.6 0.3 0.2 POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 313.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 489.2;Proximal enterocytes: 274.2;Theca cells: 647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 328.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 12000 "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" Cytosol "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" 53.4 197.4 19.9 32.1 20.7 17.9 44.7 14.1 18.6 42.0 15.5 35.9 105.2 32.1 29.4 53.6 50.2 37.0 43.3 20.7 30.2 38.1 313.3 55.0 19.9 22.2 24.5 52.2 44.5 77.6 71.4 46.3 20.9 31.8 21.9 12.7 29.9 113.1 56.2 43.8 92.4 28.2 16.9 43.8 41.5 25.5 34.7 38.0 131.3 68.1 23.2 36.6 42.3 15.3 59.6 133.0 57.0 106.3 212.9 79.8 98.0 24.4 79.3 44.7 62.3 100.7 257.0 56.1 21.9 53.1 151.8 28.3 76.0 38.4 19.6 48.1 57.9 26.0 36.9 189.4 146.5 26.2 45.5 163.9 47.4 59.2 43.2 36.3 42.3 27.1 79.1 24.0 40.8 90.9 29.0 49.4 71.7 92.9 74.8 41.0 37.6 61.1 50.0 72.8 59.3 57.4 65.4 328.4 91.0 32.6 94.0 44.2 38.6 41.7 45.8 63.6 48.7 23.8 38.3 39.0 59.3 39.8 54.9 65.9 42.6 60.4 20.6 39.6 17.1 11.0 17.5 19.4 45.6 11.2 17.1 14.7 53.8 25.9 30.2 12.5 19.3 36.6 19.9 20.7 14.1 18.6 20.7 30.2 22.2 24.5 20.9 16.9 34.7 15.3 34.3 38.5 39.7 23.2 17.1 17.1 29.4 172.3 13.1 31.4 20.5 14.0 10.9 54.3 201.4 73.5 12.5 99.9 26.0 97.7 1.9 65.0 27.6 62.1 28.0 27.1 19.8 11.8 10.1 29.4 95.0 40.1 67.8 46.6 24.7 121.4 32.2 489.2 67.8 15.2 17.1 41.7 124.1 35.2 16.1 9.5 75.8 47.3 12.4 11.2 20.5 25.9 12.3 11.6 8.8 27.9 102.0 112.5 17.0 20.7 274.2 31.7 178.6 23.0 65.7 32.7 46.9 21.3 30.8 18.2 14.6 193.2 25.4 647.6 44.5 45.9 POU2AF1 "BOB1, OBF1" ENSG00000110777 "POU class 2 homeobox associating factor 1" Q16633 11 111352255-111455630 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 119.4;stomach 1: 40.1" "Cell type enriched" "Detected in many" 4 "Plasma cells: 566.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 33.5;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 9 "B-cells: 33.5" "Group enriched" "Detected in many" 4 "Daudi: 307.2;Karpas-707: 339.3;U-266/70: 326.6;U-266/84: 159.9;U-698: 610.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011193 Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB011193: AB_532299" "prognostic favorable (1.68e-4)" "prognostic favorable (1.63e-4)" "unprognostic (1.04e-2)" "unprognostic (5.50e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.59e-4)" "unprognostic (2.09e-1)" "unprognostic (3.63e-3)" "unprognostic (7.15e-2)" "unprognostic (2.52e-2)" "unprognostic (1.34e-1)" "unprognostic (4.81e-2)" "unprognostic (8.51e-8)" "unprognostic (2.35e-1)" "unprognostic (3.90e-1)" "unprognostic (7.14e-3)" "unprognostic (1.23e-1)" 1.9 1.2 6.4 49.0 4.9 8.1 5.6 4.2 7.0 1.7 20.3 15.7 22.2 1.5 1.3 2.9 1.3 4.7 1.4 5.4 3.6 1.4 1.4 3.3 99.3 6.2 6.1 1.1 0.6 0.3 0.1 2.8 7.2 1.8 13.4 6.5 12.9 1.9 1.8 1.1 38.6 1.2 2.7 79.5 40.1 1.6 5.4 9.6 2.8 0.3 119.4 9.3 1.9 7.3 0.9 0.9 0.3 0.4 5.6 5.2 1.0 0.2 0.1 0.1 0.1 1.1 0.3 307.2 0.7 0.3 0.2 0.8 0.9 0.4 0.1 0.9 0.2 0.5 1.0 1.1 0.1 0.6 1.7 0.2 0.3 0.3 0.6 0.5 0.3 3.4 11.8 339.3 0.3 0.8 1.5 1.6 0.4 0.5 0.5 65.3 0.7 83.0 0.2 0.8 0.6 6.1 0.7 0.3 0.2 2.4 1.3 0.9 2.7 0.5 3.1 0.6 0.5 326.6 159.9 610.8 0.4 0.7 0.5 3.8 0.2 0.6 0.3 0.2 0.2 33.5 0.5 0.2 0.1 24.0 0.4 0.2 1.6 0.5 0.4 0.3 1.2 1.2 6.4 4.9 4.2 7.0 5.4 3.6 6.2 6.1 7.2 2.7 5.4 7.3 0.0 0.0 3.6 0.3 131.3 0.3 7.1 12.3 0.0 0.0 0.0 0.9 1.9 10.0 20.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 8.4 24.9 0.6 0.2 3.0 6.6 0.1 5.7 0.0 0.8 4.6 0.5 0.0 0.1 0.7 2.4 0.1 0.0 0.1 0.7 2.0 0.6 0.4 10.9 0.3 0.8 8.8 1.0 0.3 0.0 1.0 0.0 4.6 0.4 1.2 0.4 566.8 1.2 0.0 0.4 65.0 0.0 0.0 0.1 1.0 6.3 1.8 0.8 0.0 0.0 4.2 0.0 0.8 8.4 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 44.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 99.4;Hepatocytes: 144.5;Proximal enterocytes: 93.2;Rod photoreceptor cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 10.3;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;granulocytes: 10.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB075701: , HPA058901: AB_2683849, HPA067049: AB_2685770" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favorable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 7.9 6.3 9.6 4.5 12.7 6.6 3.8 9.5 6.9 4.1 23.5 11.8 18.4 3.8 3.6 7.7 4.1 4.4 26.3 7.7 8.8 22.4 33.2 4.0 3.4 11.0 11.2 11.2 8.2 7.4 2.6 4.3 10.0 6.2 9.1 18.2 7.8 5.7 26.2 7.7 18.4 4.3 8.6 4.4 6.1 1.3 11.7 3.7 7.0 44.6 3.9 5.1 4.0 10.5 7.8 1.9 2.4 8.4 13.0 8.3 5.3 6.7 13.2 7.0 7.2 3.8 3.7 2.8 3.3 15.6 6.5 3.5 7.1 8.7 6.3 8.1 8.9 8.7 4.8 8.0 8.1 6.0 14.3 6.6 6.9 5.2 11.8 6.0 1.5 6.3 3.2 6.4 6.6 2.0 6.8 2.2 0.3 6.5 1.9 8.0 8.6 3.6 4.7 4.6 2.4 7.0 2.6 2.4 8.0 3.2 2.7 4.6 2.6 7.3 7.7 6.7 2.9 6.3 4.0 1.2 11.4 6.6 2.3 1.4 0.8 10.3 1.0 1.0 0.8 0.8 0.5 0.5 0.6 1.0 0.6 0.4 0.7 0.7 0.7 3.1 1.4 0.2 9.6 12.7 9.5 6.9 7.7 8.8 11.0 11.2 10.0 8.6 11.7 10.5 15.0 3.2 13.6 49.6 8.0 23.3 15.0 7.8 9.1 15.0 14.3 11.4 99.4 22.8 8.9 7.3 62.6 8.0 18.4 58.8 9.8 10.3 0.6 9.4 26.4 15.5 19.9 32.0 1.4 16.6 6.7 16.0 14.8 18.4 5.1 19.1 22.5 144.5 8.8 5.0 13.8 31.4 0.0 24.8 10.2 1.1 19.6 10.4 3.6 10.3 12.2 16.0 8.2 19.6 27.2 13.0 24.5 30.1 10.6 19.1 93.2 40.8 5.0 148.0 6.6 31.0 15.8 0.7 1.7 19.3 34.2 3.0 9.6 14.6 37.9 19.9 PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSG00000132170 "Peroxisome proliferator activated receptor gamma" P37231 3 12287368-12434356 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 165.1" "Cell type enhanced" "Detected in many" "Adipocytes: 284.1;Extravillous trophoblasts: 217.8;Granulosa cells: 232.9;Urothelial cells: 239.6" "Cancer enhanced" "Detected in all" "urothelial cancer: 33.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 198.7;ASC TERT1: 113.7;BEWO: 247.5;CAPAN-2: 111.6;HSkMC: 118.9;PC-3: 112.0;RT4: 157.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB004282, HPA051239, HPA063663" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "CAB004282: AB_628115, HPA051239: AB_2681400, HPA063663: AB_2685081" "unprognostic (7.35e-3)" "unprognostic (3.27e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-2)" "unprognostic (2.41e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (3.41e-5)" "unprognostic (9.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.59e-8)" "unprognostic (1.51e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-3)" "prognostic favorable (5.52e-5)" 165.1 3.9 4.0 8.7 3.0 3.0 74.3 3.2 4.7 9.7 0.6 48.7 23.6 7.0 1.2 6.2 7.0 10.5 14.6 4.0 2.7 14.3 17.1 28.5 4.9 3.7 3.5 14.5 2.8 7.9 0.5 43.6 3.4 5.5 40.6 1.0 5.7 1.7 5.2 6.2 15.1 8.7 3.2 12.0 35.5 6.9 3.5 4.1 13.2 8.1 2.1 67.7 9.1 5.0 44.0 38.6 0.0 0.2 198.7 113.7 247.5 3.7 44.7 5.4 2.1 7.8 111.6 0.0 0.1 4.0 72.9 17.3 14.4 0.7 1.0 106.4 20.3 0.0 8.1 10.3 51.8 0.2 0.1 118.9 9.7 9.8 37.5 20.6 0.7 1.0 0.0 0.0 8.3 11.0 0.1 0.8 0.7 99.2 112.0 0.0 0.0 0.2 30.6 157.5 0.1 1.2 18.8 6.7 2.2 6.7 0.0 34.2 35.0 7.8 10.6 4.6 0.2 0.0 0.1 0.3 3.2 0.5 1.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 3.0 3.2 4.7 4.0 2.7 3.7 3.5 3.4 3.2 3.5 5.0 284.1 3.2 7.2 1.6 0.6 1.0 50.5 0.4 4.6 0.9 1.9 2.8 9.2 1.5 2.5 5.5 0.0 110.4 1.8 93.4 1.9 1.1 4.9 5.2 1.4 26.1 8.4 0.0 39.3 0.7 217.8 12.3 83.1 20.8 8.9 232.9 25.7 3.4 49.9 0.0 74.1 21.3 0.0 19.4 4.8 2.2 4.1 19.1 3.6 38.4 1.8 0.6 0.0 6.6 1.2 17.3 84.1 0.0 1.6 42.1 17.0 14.3 1.5 0.2 13.1 1.9 31.3 10.9 22.8 4.6 1.1 88.9 2.2 0.8 24.5 239.6 PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 259.7;skeletal muscle: 831.6;tongue: 271.1" "Cell type enriched" "Detected in many" 4 "Distal tubular cells: 1348.0" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.8;NTERA-2: 29.4;RPTEC TERT1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007811, HPA041542" Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "CAB007811: AB_598171, HPA041542: AB_2677542" "unprognostic (6.39e-3)" "unprognostic (2.61e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (2.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.71e-3)" "unprognostic (1.76e-3)" "unprognostic (2.88e-3)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (8.49e-3)" "unprognostic (7.49e-2)" 241.3 2.6 37.1 1.1 73.6 0.3 169.8 26.1 45.7 1.6 20.4 29.6 3.0 2.2 0.7 10.3 3.8 1.5 110.9 38.9 36.9 259.7 138.1 1.0 0.5 29.0 32.0 7.7 14.2 20.8 1.8 0.0 26.0 7.9 1.8 14.6 9.7 3.2 831.6 7.6 13.2 3.3 25.5 0.5 27.8 2.2 31.6 0.2 2.6 271.1 0.5 5.4 1.5 34.1 0.0 0.0 3.9 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 5.4 0.0 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 0.0 0.2 32.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 73.6 26.1 45.7 38.9 36.9 29.0 32.0 26.0 25.5 31.6 34.1 7.9 0.0 0.0 3.3 3.4 0.1 0.0 0.0 0.0 2.2 23.7 40.6 300.7 5.7 0.0 18.4 0.0 0.0 0.5 0.0 1348.0 3.5 1.6 10.4 0.5 4.6 2.4 2.7 3.1 0.4 0.1 24.5 0.0 13.8 0.0 21.0 6.4 218.4 0.6 112.7 1.8 2.1 0.0 3.8 0.0 1.9 1.2 1.6 0.0 0.0 0.0 3.7 0.0 0.0 0.5 2.5 0.1 1.2 0.0 0.3 0.5 156.8 0.0 2.8 0.0 19.2 21.6 0.2 5.9 0.0 0.3 0.0 0.9 4.2 2.0 0.2 PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766389 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.7" "Cell type enhanced" "Detected in all" "Early spermatids: 306.1;Late spermatids: 160.7;Spermatocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 173.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favorable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" 58.5 10.5 11.3 14.1 18.0 16.2 21.5 20.0 13.9 13.0 17.3 14.7 13.9 8.7 8.1 12.6 8.0 13.4 6.3 11.7 13.8 14.6 170.7 8.8 12.1 14.7 13.7 13.3 33.2 12.9 10.7 9.2 14.2 7.7 14.7 8.5 9.6 6.1 9.6 10.7 15.2 7.8 10.6 6.3 22.3 54.0 13.8 15.9 10.6 8.9 14.1 12.2 7.4 20.7 38.4 25.1 35.6 24.2 34.9 18.7 35.8 37.2 25.9 27.0 24.6 86.0 39.3 48.3 27.1 24.1 25.6 35.4 53.4 30.5 34.3 33.7 16.6 47.2 14.5 37.8 17.3 55.7 36.1 21.5 18.1 30.6 22.2 19.1 33.8 49.7 58.3 62.3 30.1 12.4 60.8 22.6 43.8 41.4 27.3 45.9 23.6 58.6 40.2 41.9 11.6 31.4 33.1 30.2 6.1 38.3 35.0 20.6 36.7 31.3 37.8 15.6 23.9 6.6 17.4 173.8 11.1 63.9 40.7 6.1 10.1 10.4 13.0 11.7 12.7 10.0 12.9 12.1 14.9 12.5 11.2 12.0 2.6 15.3 11.4 6.4 15.0 12.2 11.3 18.0 20.0 13.9 11.7 13.8 14.7 13.7 14.2 10.6 13.8 20.7 21.2 19.2 10.5 63.3 11.0 14.3 11.0 12.0 18.2 5.4 14.1 8.5 3.2 15.7 13.4 12.9 8.4 13.5 11.0 23.8 13.7 18.7 306.1 29.6 13.4 20.2 15.6 32.4 23.8 22.9 20.3 12.3 15.3 46.1 8.2 34.3 9.3 89.4 9.5 1.7 14.5 11.5 22.4 5.8 9.2 160.7 6.5 7.5 8.8 17.8 8.9 9.9 7.2 26.2 49.1 23.6 9.0 7.5 9.0 10.9 16.2 17.6 16.8 11.0 13.1 14.5 14.4 135.9 20.8 12.0 14.6 17.6 11.0 9.7 13.9 15.0 PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.6" "Cell type enhanced" "Detected in all" "Late spermatids: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA051066: AB_2681333" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (3.93e-2)" "unprognostic (8.54e-2)" "unprognostic (9.08e-3)" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-3)" "unprognostic (9.99e-3)" "unprognostic (3.56e-2)" "unprognostic (2.96e-1)" "unprognostic (4.89e-1)" "unprognostic (1.93e-1)" "unprognostic (9.23e-2)" 22.8 35.9 46.0 9.8 48.1 8.7 19.3 48.6 50.6 15.1 54.1 29.0 25.2 12.6 16.3 25.8 11.3 9.8 101.4 45.8 46.9 27.0 71.5 12.7 9.2 47.6 47.3 11.0 41.6 21.2 23.1 8.2 47.4 19.3 21.4 15.5 29.1 14.7 126.6 20.6 22.1 14.8 46.7 23.6 27.1 31.3 49.0 11.0 17.9 107.1 9.9 23.1 16.3 46.4 21.7 16.6 16.2 31.3 49.3 19.2 22.6 37.8 15.1 32.5 18.7 46.6 20.6 23.3 20.2 38.0 29.3 19.5 25.8 22.7 23.0 36.2 28.2 36.7 21.4 35.2 15.3 20.3 33.7 25.0 13.5 29.2 15.4 9.4 30.5 39.0 32.4 46.1 37.8 41.9 51.7 34.0 5.2 93.7 74.2 31.0 68.6 71.8 18.6 19.0 34.5 12.3 18.1 42.5 15.7 17.3 22.5 15.7 18.9 37.6 16.6 32.9 31.8 52.2 43.9 22.3 24.0 39.6 15.7 15.6 35.0 35.4 24.8 84.3 20.1 17.5 23.8 23.6 36.3 21.8 22.3 19.5 5.0 39.2 105.3 73.3 31.1 48.2 46.0 48.1 48.6 50.6 45.8 46.9 47.6 47.3 47.4 46.7 49.0 46.4 21.7 9.6 4.6 10.1 11.0 15.6 11.3 34.5 4.6 15.2 23.3 23.9 62.6 15.7 20.0 14.7 8.4 25.7 25.4 44.7 72.4 23.3 57.3 12.1 9.3 17.7 32.3 4.2 6.9 46.9 47.2 20.4 13.7 6.0 28.6 4.8 30.7 63.0 49.1 11.8 6.9 47.7 44.7 25.5 14.0 144.3 16.8 19.3 16.0 1.9 7.2 31.4 21.6 6.0 7.0 23.2 31.2 16.1 29.2 10.7 101.4 65.2 15.8 28.3 32.9 19.1 19.1 61.5 21.1 30.1 24.0 13.5 9.7 27.2 50.2 15.4 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;urinary bladder: 9.0" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Endometrial stromal cells: 6.5;Excitatory neurons: 7.9;Fibroblasts: 10.7;Late spermatids: 7.1;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;HEK 293: 5.2;HEL: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.3" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 0.7 0.1 0.2 0.3 0.2 0.0 0.6 0.2 0.3 0.9 0.6 4.9 0.2 0.7 0.1 0.6 0.4 3.3 0.5 0.1 0.2 0.3 0.1 2.9 0.0 0.3 0.4 1.9 0.3 0.1 0.3 4.2 0.4 1.3 1.0 0.2 0.1 0.1 0.1 0.2 0.6 0.7 0.3 0.0 0.6 0.3 0.2 0.0 0.8 0.2 0.2 9.0 0.6 0.3 0.0 0.0 0.0 0.3 0.3 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.1 5.2 1.1 0.5 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.4 0.4 0.3 0.2 0.3 0.5 0.0 0.0 15.0 0.0 1.9 0.1 0.0 0.0 1.0 0.6 0.3 1.4 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.1 3.3 0.6 6.5 0.5 0.0 0.0 7.9 0.2 0.3 10.7 0.0 0.5 0.0 2.4 0.0 0.5 0.8 0.0 6.4 0.1 0.0 0.8 3.5 7.1 2.1 0.4 3.6 4.7 0.8 0.2 0.0 3.0 11.0 0.1 0.0 1.2 0.1 0.2 0.0 0.8 0.2 1.0 0.0 0.7 2.2 2.3 4.4 0.2 1.3 0.4 0.4 6.1 0.0 0.1 PRDM8 KMT8D ENSG00000152784 "PR/SET domain 8" Q9NQV8 4 80183879-80204329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 26.1;seminal vesicle: 27.2" "Cell type enriched" "Detected in many" 9 "Bipolar cells: 271.5" "Cancer enhanced" "Detected in many" "prostate cancer: 4.6" "Region enhanced" "Detected in many" "cerebral cortex: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 27.3;LHCN-M2: 41.7;NB-4: 48.2;SCLC-21H: 99.3" "Region enhanced" "Detected in many" "hippocampal formation: 28.7" "Low region specificity" "Detected in all" HPA057253 Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 24: B-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Nuclear bodies" Nucleoplasm "HPA057253: AB_2683382" "unprognostic (2.33e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (1.65e-1)" "unprognostic (7.95e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (2.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.89e-11)" "unprognostic (4.64e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-1)" 4.8 2.3 5.1 5.0 10.2 4.0 4.0 0.0 17.0 11.7 0.0 11.4 1.1 9.3 1.9 1.7 5.2 1.7 1.7 13.7 0.0 1.3 0.3 1.6 5.1 0.0 0.0 5.2 0.9 0.0 5.4 4.3 0.0 26.1 1.5 24.1 1.4 27.2 2.2 2.7 5.7 3.8 0.6 1.8 5.0 1.1 0.1 0.7 1.2 0.9 2.4 10.2 9.8 3.2 2.3 0.2 0.7 0.0 2.1 7.2 0.1 5.8 20.5 2.8 3.2 0.0 2.2 0.0 0.0 7.2 1.8 0.7 0.1 2.4 12.1 8.8 1.8 0.8 0.0 0.0 4.1 9.1 2.5 4.4 0.2 11.1 3.2 27.3 0.4 2.4 0.0 3.7 41.7 0.0 4.2 48.2 0.0 0.2 17.0 1.6 0.0 0.2 1.2 0.3 99.3 13.8 0.3 0.0 0.1 0.1 0.0 4.5 8.8 7.1 1.0 5.2 0.4 1.7 0.0 0.0 17.8 4.2 1.0 0.0 0.0 0.0 0.4 0.0 0.6 0.1 0.5 0.5 0.1 0.7 0.3 0.1 0.5 0.2 0.0 0.1 0.2 0.1 5.1 10.2 0.0 17.0 13.7 0.0 0.0 0.0 0.0 0.6 0.1 3.2 0.9 0.0 0.5 2.3 8.2 0.6 3.4 0.4 0.0 271.5 0.1 0.4 1.8 0.0 5.2 1.8 2.1 0.0 2.5 0.0 0.0 0.0 1.5 0.3 6.5 2.2 0.0 2.5 29.9 0.2 0.2 8.8 0.0 0.5 0.0 0.1 0.0 0.0 0.5 3.3 2.0 0.2 2.0 1.2 6.2 6.7 3.1 5.9 1.8 3.7 0.9 6.1 2.1 7.1 17.0 0.7 0.0 3.4 2.7 3.7 0.0 0.2 5.0 11.6 0.0 4.2 2.9 0.3 0.4 0.0 0.1 0.1 5.0 0.1 0.0 0.6 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477330-173488815 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1315.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 340.7 157.5 169.5 68.3 181.3 100.1 211.2 197.6 210.1 112.3 164.8 189.1 46.4 108.8 206.3 127.9 149.8 71.9 261.8 184.1 196.6 184.4 482.5 116.7 72.2 181.0 198.3 115.5 114.4 217.5 67.4 70.7 187.5 152.1 221.6 53.9 85.6 99.0 563.5 106.6 59.8 160.2 175.8 70.7 135.2 119.1 176.7 70.7 106.0 382.4 79.0 99.5 109.8 185.5 420.3 127.7 204.7 230.9 778.5 372.7 169.5 843.9 284.3 342.7 241.8 243.9 276.4 272.4 256.4 694.2 120.4 239.8 272.0 259.9 279.0 234.0 243.6 179.5 200.0 277.7 425.7 191.3 56.1 301.0 262.6 181.3 256.6 210.8 339.5 106.7 405.4 52.8 392.9 86.3 131.7 249.1 456.2 219.8 760.5 154.5 236.6 277.0 518.1 95.4 94.9 173.4 285.0 334.0 199.2 296.3 283.8 262.9 228.2 132.5 149.9 201.8 229.5 76.4 123.2 220.7 159.4 162.3 124.3 36.2 42.5 24.8 29.8 39.8 32.8 32.6 29.8 38.4 53.5 24.4 39.8 47.9 25.2 25.7 36.5 79.7 36.1 58.1 169.5 181.3 197.6 210.1 184.1 196.6 181.0 198.3 187.5 175.8 176.7 185.5 278.1 176.3 170.8 127.3 127.4 235.4 404.1 382.8 209.5 31.9 186.1 250.7 528.6 301.7 228.6 277.7 29.2 714.3 158.6 1315.9 860.8 178.6 237.5 206.9 226.8 191.8 142.1 449.5 13.8 202.3 939.1 307.0 111.6 200.0 348.6 216.6 214.2 1120.2 345.0 45.4 13.2 257.4 205.4 164.3 161.0 667.5 340.5 227.1 183.2 17.8 212.9 462.5 83.4 12.5 15.4 147.2 663.4 416.8 176.4 427.1 264.4 827.3 209.1 52.0 184.1 185.7 253.8 123.5 76.8 305.9 264.1 963.5 157.7 512.5 303.6 308.9 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in some" "dendritic cells: 542.1;NK-cells: 1231.7;T-cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8" "Group enriched" "Detected in all" 50 "NK-cells: 656.8;T-cells: 900.4" "Cell line enriched" "Detected in some" 11 "HDLM-2: 240.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" NA NA 2100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" 5.0 2.0 0.7 7.6 0.7 28.6 2.7 0.7 1.3 1.3 1.3 2.2 2.3 3.5 1.1 1.9 1.9 4.2 2.2 0.6 0.6 1.7 6.3 16.5 20.3 1.4 0.7 1.0 1.0 0.5 0.9 2.7 1.0 1.5 1.4 0.0 2.3 1.2 2.6 0.9 5.2 2.0 1.3 49.4 4.7 0.6 1.0 5.8 2.6 1.5 4.9 3.8 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 240.1 0.0 1.4 0.0 7.4 0.0 0.3 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 5.2 1.9 0.9 900.4 1.7 628.8 4.0 125.8 499.1 2.0 3.5 52.1 313.0 15.4 656.8 2.6 2.9 108.8 587.5 0.7 0.7 0.7 1.3 0.6 0.6 1.4 0.7 1.0 1.3 1.0 1.0 3.1 3.2 13.6 0.0 4.4 0.4 0.1 0.0 0.6 0.0 0.5 0.5 0.8 1.5 2.5 0.0 0.0 0.2 542.1 0.1 0.0 0.3 0.0 0.2 0.3 1.9 0.0 19.0 0.0 0.0 0.1 2.1 7.7 0.4 8.8 0.0 10.8 2.7 0.1 0.0 0.0 0.0 0.0 7.8 2.3 0.0 0.0 5.7 0.0 1.9 7.4 0.0 1231.7 0.0 0.1 0.0 0.0 0.0 88.5 0.1 0.1 1.6 1.5 0.0 0.0 1.1 0.8 0.0 0.0 0.5 0.9 0.7 265.4 0.0 0.1 0.0 PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044705-107161811 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 135.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 110.2;Excitatory neurons: 146.3;Granulosa cells: 712.1;Theca cells: 271.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 70.7;Daudi: 99.8;K-562: 61.4;U-698: 254.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008421, HPA063879" Enhanced Uncertain Mitochondria NA NA 570000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008421: AB_1855421, HPA063879: " "unprognostic (3.18e-1)" "unprognostic (2.48e-2)" "prognostic favorable (6.38e-4)" "unprognostic (1.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.43e-3)" "unprognostic (2.76e-1)" "unprognostic (8.14e-3)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.50e-1)" "unprognostic (5.12e-3)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.74e-4)" "unprognostic (7.15e-2)" 135.8 44.9 10.7 4.8 12.1 14.2 51.3 5.7 17.5 8.0 5.3 11.1 3.6 6.9 4.4 11.2 7.0 4.9 15.5 13.2 9.5 8.8 2.5 7.6 3.8 6.2 10.2 26.4 8.7 6.5 11.4 15.1 8.3 9.2 6.9 7.5 9.9 4.4 1.5 3.7 11.5 5.1 6.9 16.7 9.1 13.6 7.8 2.6 3.5 6.1 4.0 20.3 6.2 10.1 0.1 1.5 9.1 70.7 36.8 0.0 0.1 3.6 11.5 3.0 2.7 0.0 0.2 99.8 0.8 2.3 8.6 0.1 7.1 0.0 5.5 2.8 7.9 33.3 0.1 0.0 10.3 0.6 4.5 0.5 0.0 0.3 0.0 3.1 42.9 5.4 61.4 2.9 0.1 7.5 14.0 0.4 17.3 0.0 2.8 4.0 0.2 0.0 0.1 0.1 11.6 16.7 5.4 1.2 3.9 22.9 2.1 7.0 24.4 3.5 9.2 0.0 7.1 2.1 0.1 254.8 2.5 17.5 33.9 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.6 10.7 12.1 5.7 17.5 13.2 9.5 6.2 10.2 8.3 6.9 7.8 10.1 39.6 3.2 1.5 9.8 1.9 2.4 1.6 2.1 0.6 33.5 27.9 10.5 35.9 12.8 5.1 7.3 10.4 0.1 3.7 1.7 0.0 2.5 7.9 1.8 16.2 17.4 0.0 110.2 146.3 0.0 0.6 17.5 3.6 0.9 4.5 712.1 19.2 0.0 1.6 5.0 71.9 1.9 4.1 19.6 26.4 8.5 29.8 64.1 17.8 15.9 17.0 6.4 3.1 60.8 10.9 0.1 2.1 53.0 2.0 3.5 0.0 0.8 5.4 11.9 19.7 5.4 57.7 2.5 6.5 0.7 2.4 0.0 3.7 271.7 2.7 4.6 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 57.0;granulocytes: 52.9;monocytes: 73.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 267.7;THP-1: 194.0" "Group enriched" "Detected in all" 5 "basal ganglia: 121.4;thalamus: 334.6" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 30000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 46.1 59.7 10.4 45.4 11.1 90.3 28.9 4.4 11.7 25.9 7.3 43.5 54.8 9.1 39.1 32.7 42.3 32.8 19.6 12.8 11.0 25.6 8.8 44.3 46.8 9.9 8.5 13.6 33.2 20.7 8.2 20.5 7.5 39.3 41.5 2.2 25.9 31.9 6.8 34.0 55.7 16.2 9.5 54.2 65.1 20.8 9.0 16.3 41.8 9.2 62.1 44.2 23.2 12.3 33.5 14.4 5.2 8.7 35.9 21.6 46.2 20.4 25.7 24.5 23.7 34.4 31.9 86.5 8.3 45.6 42.9 14.5 34.1 49.8 20.6 75.2 23.6 50.1 18.3 32.0 23.6 64.8 103.4 17.1 35.8 25.6 23.2 21.8 22.4 9.3 9.7 11.8 36.1 85.0 7.0 81.0 13.0 51.5 23.0 7.6 13.6 20.6 25.5 72.8 8.3 6.5 15.4 267.7 39.6 24.0 22.6 194.0 31.5 11.7 14.4 15.4 19.2 18.1 33.6 45.9 27.6 116.4 22.6 51.8 73.7 50.1 3.6 71.3 2.2 6.2 2.1 2.5 57.0 8.2 2.2 2.0 52.9 6.9 47.7 16.3 2.6 24.1 10.4 11.1 4.4 11.7 12.8 11.0 9.9 8.5 7.5 9.5 9.0 12.3 4.3 3.2 23.5 2.0 25.7 29.2 26.3 8.0 23.9 0.3 11.8 4.3 6.4 14.3 16.1 14.7 0.0 3.1 24.7 61.8 3.9 8.9 34.5 18.5 4.4 2.7 26.5 5.2 3.4 10.7 16.0 6.7 54.0 17.8 5.7 8.9 3.3 2.3 44.8 1.7 4.2 37.1 4.1 47.4 43.0 75.6 9.0 41.5 10.6 20.6 44.9 2.0 8.2 1.0 0.5 13.2 55.4 6.8 25.8 19.7 64.5 13.1 16.5 0.2 6.6 6.5 12.1 23.1 3.7 23.9 27.8 8.8 10.0 10.4 23.0 34.6 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 33.6;skeletal muscle: 124.5;tongue: 112.6" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;dendritic cells: 22.4;NK-cells: 32.0;Oligodendrocyte precursor cells: 24.6;Oligodendrocytes: 75.2;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.0;MAIT T-cell: 18.0;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.5;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.7" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.7" "Cell line enhanced" "Detected in many" "HEL: 57.8;JURKAT: 40.0;MOLT-4: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.8 0.7 5.3 5.2 8.5 5.7 0.9 6.1 6.3 1.6 12.1 1.4 1.5 2.5 8.3 2.2 3.9 1.5 0.3 5.5 8.2 10.9 1.0 5.3 12.3 6.5 8.6 1.3 3.4 0.7 0.8 0.2 6.4 1.8 1.7 1.5 1.4 1.1 124.5 0.3 3.3 0.7 5.5 5.0 2.1 1.1 7.2 33.6 14.9 112.6 9.4 2.2 0.6 9.8 0.1 5.3 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.2 0.4 3.4 0.3 0.0 0.0 0.0 0.0 3.3 6.0 0.0 0.0 3.9 57.8 0.0 0.4 0.7 2.8 0.6 0.3 3.5 0.1 0.2 0.0 0.5 40.0 12.8 0.1 0.0 0.0 43.9 8.0 5.8 0.5 0.0 8.5 1.3 0.0 11.6 2.9 0.4 2.1 0.0 0.0 0.0 3.4 0.0 5.8 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 2.4 0.1 0.3 23.0 0.4 18.0 0.1 24.5 24.5 0.2 0.0 19.1 17.9 1.6 13.3 0.0 0.0 39.7 10.5 5.3 8.5 6.1 6.3 5.5 8.2 6.5 8.6 6.4 5.5 7.2 9.8 0.2 3.2 7.0 22.9 0.8 0.0 0.3 0.3 0.6 1.6 0.3 0.3 0.4 0.0 0.7 1.8 0.0 0.0 22.4 0.0 7.9 0.3 2.1 0.5 1.2 0.2 1.8 8.0 13.7 0.8 0.1 0.7 1.5 3.0 1.3 8.2 1.1 0.0 0.5 0.0 14.7 0.5 0.0 1.3 0.5 5.6 0.0 1.7 0.0 7.5 0.8 1.2 32.0 24.6 75.2 0.1 0.1 0.0 10.2 0.2 0.0 0.3 0.9 0.4 0.0 4.2 0.4 1.0 2.2 0.5 0.0 0.0 31.7 0.3 0.4 0.1 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 362.1;Excitatory neurons: 147.4;Inhibitory neurons: 171.1;Microglial cells: 89.0;Oligodendrocyte precursor cells: 390.6" "Cancer enhanced" "Detected in all" "prostate cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 21.6;fHDF/TERT166: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 8.0 9.6 5.6 2.2 8.0 0.0 7.7 6.5 6.7 6.4 3.7 9.5 1.0 7.9 3.5 2.1 6.5 4.4 6.1 7.5 7.5 17.5 1.6 7.5 0.3 8.6 8.6 11.2 5.4 10.6 5.6 1.9 8.7 14.7 1.3 4.7 2.9 9.3 1.6 2.8 3.6 6.3 8.9 2.3 4.6 11.7 8.1 2.4 5.9 2.6 0.5 13.1 4.6 10.3 0.0 4.4 4.8 3.1 21.6 16.5 0.1 14.1 10.4 16.7 7.3 0.0 0.3 0.0 1.9 19.4 4.0 0.1 7.9 2.1 6.8 0.0 6.2 0.0 0.0 0.5 8.8 0.0 0.1 18.4 0.3 1.4 1.5 6.1 2.6 0.0 1.4 0.4 17.4 1.8 0.0 0.0 2.6 0.0 9.6 0.0 6.3 5.2 9.7 6.6 4.3 13.0 2.6 0.0 4.5 4.6 0.0 0.1 5.6 13.6 6.7 1.0 3.7 0.0 0.0 0.0 3.5 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.0 6.5 6.7 7.5 7.5 8.6 8.6 8.7 8.9 8.1 10.3 4.6 0.0 7.4 362.1 0.2 0.5 4.8 0.4 0.6 1.4 1.4 1.5 1.2 10.0 0.0 12.9 6.2 0.0 0.0 0.1 29.4 2.4 39.5 2.8 9.2 6.1 3.0 2.7 147.4 4.2 0.1 6.4 0.5 8.4 0.0 18.7 10.8 2.5 0.2 1.7 171.1 0.2 0.0 1.6 0.9 16.9 7.5 0.7 7.2 89.0 0.0 16.7 0.0 390.6 76.6 2.0 0.1 12.8 0.4 12.4 0.2 4.5 0.1 2.9 0.0 13.3 4.5 3.2 7.8 0.0 0.9 0.3 0.6 29.6 0.1 1.3 PRKG1 "PGK, PKG, PKG1, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase cGMP-dependent 1" Q13976 10 50990888-52298423 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 778.3;Excitatory neurons: 244.9;Inhibitory neurons: 473.0;Microglial cells: 188.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 36 "basophil: 7.3" "Lineage enriched" "Detected in single" 49 "granulocytes: 7.3" "Cell line enhanced" "Detected in many" "AN3-CA: 14.3;BJ hTERT+: 19.2;fHDF/TERT166: 16.1;U-138 MG: 11.2;U-87 MG: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 7.0 8.3 6.4 2.7 7.2 0.6 3.1 1.4 6.9 10.3 12.4 5.5 2.4 10.3 3.5 5.2 5.2 7.0 14.1 6.6 10.7 3.8 1.7 6.8 1.2 5.1 4.6 4.2 1.7 9.6 1.3 10.1 3.2 6.4 5.3 3.6 4.0 8.1 25.8 1.0 3.4 14.6 5.3 2.5 3.3 1.8 12.2 1.5 7.0 36.1 0.9 5.4 4.2 2.7 0.1 0.2 1.7 14.3 6.5 6.0 0.1 5.4 19.2 2.1 2.6 0.1 0.9 0.3 0.0 16.1 2.0 0.1 0.0 0.1 1.7 0.0 5.0 1.0 0.3 0.0 5.5 0.0 0.1 8.1 0.1 4.8 0.1 0.6 0.0 0.0 0.0 0.1 5.3 0.1 0.0 0.0 4.1 0.0 2.5 0.0 3.9 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 2.0 0.1 0.0 0.0 11.2 1.9 5.9 3.7 1.5 0.8 0.0 10.0 0.0 2.5 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 6.4 7.2 1.4 6.9 6.6 10.7 5.1 4.6 3.2 5.3 12.2 2.7 10.5 16.0 10.8 778.3 0.3 0.9 1.7 0.0 7.4 5.9 2.8 9.4 31.4 0.0 0.0 3.7 0.0 1.0 0.3 2.9 0.0 2.4 56.0 0.4 14.7 7.1 0.0 3.4 244.9 3.6 1.2 24.2 0.5 0.5 4.5 0.1 5.0 0.0 0.4 0.0 473.0 4.2 0.0 0.0 2.2 53.0 32.6 5.3 3.6 188.3 0.0 23.6 0.0 24.6 8.0 4.8 14.1 39.5 0.1 0.5 3.2 0.2 0.9 1.3 39.5 3.9 69.9 0.9 0.9 1.6 0.6 2.2 0.2 7.9 3.6 1.0 PRNP "AltPrP, CD230, CJD, GSS, PRIP, PRP" ENSG00000171867 "Prion protein" P04156 20 4686350-4701590 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" Prion "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 412.6;Basal squamous epithelial cells: 369.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "basophil: 875.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 875.9" "Cell line enhanced" "Detected in many" "WM-115: 1039.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042754, HPA043398" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol" NA Yes 5100000 "Cluster 38: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nuclear membrane, Cytosol" Vesicles "HPA042754: AB_10964203, HPA043398: AB_2678461" "unprognostic (1.50e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.96e-4)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.94e-2)" "prognostic unfavorable (7.41e-5)" "unprognostic (7.60e-3)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (3.44e-1)" "unprognostic (1.04e-1)" "unprognostic (6.75e-2)" "unprognostic (7.28e-3)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.69e-2)" 87.0 92.4 283.8 52.4 308.4 83.7 106.7 255.1 385.9 135.4 415.8 184.2 37.1 125.5 59.1 79.2 79.9 110.1 197.5 315.6 244.8 132.8 79.7 79.2 59.8 262.8 260.8 163.7 41.5 62.8 83.8 66.9 270.1 146.1 70.5 178.6 60.3 148.2 64.0 95.4 47.4 140.8 265.0 75.2 61.6 68.1 302.5 47.9 89.1 74.0 60.0 124.9 83.4 292.8 226.4 141.6 41.7 64.2 329.6 199.9 36.6 363.4 527.6 175.5 177.7 50.0 171.5 40.9 79.2 727.9 391.8 508.8 45.9 498.3 326.2 31.8 39.0 0.2 19.6 193.8 402.0 72.8 16.5 177.5 711.9 701.8 583.9 257.0 152.8 28.6 22.8 142.9 205.1 45.7 28.8 46.2 33.1 99.8 266.4 33.9 110.0 38.3 88.7 40.3 49.2 7.0 98.9 144.3 554.1 56.4 30.2 38.8 224.5 282.9 127.1 158.6 296.1 63.1 129.5 132.9 226.8 51.9 1039.0 875.9 74.1 5.4 67.3 60.9 100.7 25.1 56.9 55.8 62.9 25.6 33.5 40.1 4.6 23.6 50.4 24.6 72.8 72.7 283.8 308.4 255.1 385.9 315.6 244.8 262.8 260.8 270.1 265.0 302.5 292.8 44.9 80.1 45.4 120.2 85.3 412.6 211.8 132.5 369.3 265.4 60.8 103.0 257.7 32.9 68.2 33.1 116.7 7.7 71.8 2.6 11.7 58.1 6.0 14.1 73.2 66.7 29.9 31.8 125.5 14.7 6.3 177.4 14.8 18.2 173.0 25.5 41.0 36.2 63.6 45.4 170.8 5.4 40.7 219.1 200.4 13.6 143.2 126.3 168.9 59.0 54.5 142.4 42.2 95.0 158.8 18.7 4.5 170.0 47.0 120.3 2.2 84.0 38.1 99.0 13.1 73.0 82.3 36.6 4.5 81.6 284.4 14.4 107.2 10.3 8.8 122.6 PROB1 C5orf65 ENSG00000228672 "Proline rich basic protein 1" E7EW31 5 139390592-139395104 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.3;skeletal muscle: 81.0" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "HDLM-2: 104.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA053354, HPA060103" Enhanced Enhanced Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA053354: , HPA060103: AB_2684205" "unprognostic (4.14e-2)" "prognostic favorable (9.26e-4)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.53e-2)" "unprognostic (9.27e-3)" "unprognostic (4.72e-2)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "unprognostic (3.21e-2)" "unprognostic (4.84e-4)" "unprognostic (7.10e-2)" "unprognostic (1.75e-2)" "unprognostic (9.05e-2)" "unprognostic (3.62e-2)" "unprognostic (5.89e-2)" "unprognostic (8.24e-2)" 1.4 4.8 4.2 0.9 3.3 0.4 1.5 3.5 2.5 1.4 2.2 1.9 1.2 1.7 0.4 1.0 2.1 0.4 23.3 3.3 4.5 1.7 0.6 0.9 1.0 6.4 7.8 0.6 0.4 2.3 2.9 0.6 4.9 3.3 0.1 0.3 2.4 1.3 81.0 0.7 1.6 0.5 6.1 1.6 1.2 0.8 5.0 0.7 1.0 18.4 0.6 1.6 1.0 2.9 1.5 0.6 0.3 0.3 0.1 0.3 0.5 1.2 0.3 1.3 1.1 4.3 2.6 5.7 1.1 3.9 0.1 0.7 0.5 0.1 0.3 104.7 1.4 1.4 2.7 0.5 3.0 0.0 3.2 0.9 0.7 2.8 0.6 0.7 0.1 3.7 0.5 5.7 4.1 1.2 4.9 2.6 1.4 0.6 2.7 15.4 0.4 12.5 0.2 0.1 1.3 0.7 6.0 4.5 0.2 1.3 2.1 3.0 0.4 0.1 0.4 0.2 0.4 1.0 1.8 9.2 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.2 3.3 3.5 2.5 3.3 4.5 6.4 7.8 4.9 6.1 5.0 2.9 2.4 0.0 0.0 0.0 0.7 0.0 0.3 0.0 1.2 0.0 0.4 0.1 29.7 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.2 2.4 1.5 2.5 0.0 0.4 0.0 0.0 0.3 1.2 1.1 0.9 0.0 0.7 2.9 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.3 0.1 1.2 3.0 0.3 0.0 2.4 0.0 0.2 6.6 5.6 2.9 0.4 0.8 0.3 0.0 2.6 0.4 2.4 0.6 0.3 PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 83.1;Hepatocytes: 307.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 112.3;ASC TERT1: 100.1;HSkMC: 78.2;SK-MEL-30: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" 33.6 8.7 1.7 8.1 1.3 0.3 24.7 1.6 2.7 14.9 107.5 17.3 13.5 16.4 2.0 16.6 19.4 33.7 116.6 3.2 2.2 37.7 283.1 39.2 4.7 2.1 2.4 32.6 5.6 13.5 8.5 32.0 2.2 8.4 21.6 4.6 12.3 10.3 4.9 20.5 20.6 19.2 1.6 11.2 10.5 5.0 2.3 1.5 17.0 16.9 3.7 18.5 15.1 1.7 0.4 2.7 3.0 27.1 112.3 100.1 1.6 4.6 9.4 1.0 6.6 12.7 1.4 0.0 30.0 3.0 18.8 0.0 1.4 0.9 1.8 0.1 7.3 51.4 1.4 29.8 8.7 1.5 1.2 78.2 0.4 4.0 0.6 63.0 7.2 3.7 32.8 0.1 49.2 0.0 0.1 0.0 3.1 2.7 6.5 0.3 1.2 0.0 27.7 0.0 7.6 19.8 5.0 0.0 157.0 0.6 0.0 19.9 9.4 14.8 2.8 8.2 1.7 0.0 0.0 0.0 60.4 30.4 27.8 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 3.2 1.7 1.3 1.6 2.7 3.2 2.2 2.1 2.4 2.2 1.6 2.3 1.7 55.9 64.1 33.8 17.9 1.9 14.8 3.6 2.1 4.0 0.5 1.7 14.0 44.6 14.3 7.5 1.8 10.4 0.6 0.5 7.5 3.9 9.8 3.2 2.1 30.7 47.1 15.7 16.4 28.4 4.4 0.7 83.1 2.0 1.1 30.9 5.0 65.7 307.1 12.8 1.7 19.7 11.6 0.0 31.5 20.6 6.3 28.6 14.6 19.6 27.2 1.3 22.8 0.0 10.6 4.6 5.6 19.3 36.9 0.3 4.5 1.9 42.2 56.6 8.1 13.1 32.4 28.4 0.4 0.7 11.8 33.2 1.6 2.1 10.8 12.6 2.3 PRPH "NEF4, PRPH1" ENSG00000135406 Peripherin P41219 12 49293252-49298686 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.6;intestine: 21.0" "Group enriched" "Detected in some" 6 "Early spermatids: 327.5;Late spermatids: 920.2" "Group enriched" "Detected in some" 4 "endometrial cancer: 1.6;glioma: 1.7;pancreatic cancer: 1.1;testis cancer: 1.5" "Group enriched" "Detected in many" 5 "medulla oblongata: 51.9;pons: 53.6;white matter: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "AN3-CA: 367.0" "Group enriched" "Detected in many" 4 "hypothalamus: 19.4;pons and medulla: 35.1" "Region enriched" "Detected in many" 8 "spinal cord: 256.8" "CAB002437, HPA039277, HPA063887" Enhanced NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "CAB002437: AB_563956, HPA039277: AB_2676424, HPA063887: AB_2685142" "unprognostic (1.73e-2)" "unprognostic (3.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.04e-3)" "unprognostic (1.88e-2)" "unprognostic (6.29e-2)" "unprognostic (1.87e-1)" "unprognostic (2.10e-1)" "unprognostic (7.38e-2)" "unprognostic (1.24e-1)" "unprognostic (4.25e-3)" "unprognostic (3.63e-2)" "unprognostic (5.73e-2)" "unprognostic (4.86e-3)" "unprognostic (6.36e-5)" 3.1 14.5 0.9 7.5 1.1 0.0 1.8 0.3 1.8 3.3 0.4 21.0 4.7 0.8 0.1 0.5 3.1 0.6 1.2 0.9 2.2 0.9 0.1 0.9 0.2 51.9 8.0 0.7 1.3 0.1 2.9 0.3 53.6 2.3 2.1 1.5 0.5 1.5 0.4 1.1 8.9 2.0 7.8 1.2 5.2 13.2 0.9 0.1 0.5 0.2 0.1 1.5 8.3 15.7 0.0 0.7 0.0 367.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.7 1.6 0.4 1.3 0.2 0.2 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.7 0.0 0.2 2.0 0.0 2.2 0.4 0.0 1.6 86.6 1.5 0.2 0.8 0.0 0.0 1.7 0.1 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.3 1.8 0.9 2.2 51.9 8.0 53.6 7.8 0.9 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 10.8 0.3 0.8 0.4 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.0 327.5 0.5 0.1 1.4 92.3 0.0 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 25.2 0.1 1.0 0.0 0.0 0.9 920.2 5.9 0.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.8 0.1 38.1 0.0 0.1 14.1 96.1 19.4 0.3 0.4 0.0 0.1 0.0 0.5 0.2 PRR15 ENSG00000176532 "Proline rich 15" Q8IV56 7 29563835-29567293 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 62.6;intestine: 81.4;stomach 1: 49.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 263.0;Granulosa cells: 194.2;Proximal enterocytes: 122.4;Respiratory ciliated cells: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.7;HaCaT: 45.1;OE19: 97.7;RT4: 34.5;SK-BR-3: 74.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA040996, HPA048121" Enhanced Uncertain "Vesicles,Cell Junctions" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "HPA040996: AB_2677241, HPA048121: AB_2680271" "unprognostic (5.46e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "prognostic favorable (6.37e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (3.69e-3)" "unprognostic (1.25e-1)" "prognostic favorable (1.83e-6)" "unprognostic (1.30e-2)" "unprognostic (5.71e-2)" "unprognostic (2.33e-3)" "unprognostic (1.58e-2)" 6.5 0.7 0.6 4.8 0.4 1.1 9.2 0.1 0.7 62.6 0.0 81.4 72.3 18.1 21.6 1.0 9.0 7.8 1.3 0.4 1.0 16.9 0.3 2.3 0.4 0.6 0.4 5.9 3.0 1.4 3.0 4.8 0.5 2.5 52.6 0.0 7.5 3.1 0.2 0.3 72.4 2.3 0.6 0.2 49.3 0.9 1.3 0.1 1.1 0.0 0.7 16.6 0.5 0.6 16.8 23.3 0.0 0.0 8.7 10.7 29.3 0.7 1.1 0.4 0.2 20.5 38.7 0.0 4.1 5.5 0.6 45.1 4.9 0.0 0.0 0.0 3.3 1.3 4.5 22.7 2.8 0.0 0.1 0.1 7.3 0.0 1.7 0.0 0.1 1.5 0.0 0.0 0.0 3.9 0.6 3.2 3.5 97.7 18.5 0.1 0.0 21.4 26.5 34.5 0.5 0.3 2.3 74.9 0.0 12.8 5.4 0.0 19.9 0.5 0.0 0.1 0.9 1.8 3.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.4 0.1 0.7 0.4 1.0 0.6 0.4 0.5 0.6 1.3 0.6 1.8 0.0 0.5 0.0 0.4 0.1 1.2 11.0 0.0 0.0 10.0 7.1 0.5 12.8 16.4 38.6 0.0 14.2 0.2 263.0 29.4 6.9 0.8 31.3 2.3 1.2 8.4 0.0 0.1 21.8 9.9 1.3 16.8 34.7 0.0 194.2 0.4 0.2 2.7 0.0 0.0 45.3 26.4 0.0 0.3 0.1 1.5 2.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 14.4 58.5 2.2 0.1 3.0 122.4 14.4 63.1 0.0 0.0 0.0 7.8 0.0 0.4 1.2 0.0 6.3 0.6 0.4 56.9 23.3 PRR15L "ATAD4, MGC11242" ENSG00000167183 "Proline rich 15 like" Q9BU68 17 47951967-47957883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 178.4;pancreas: 103.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 203.0;Distal tubular cells: 170.2;Intestinal goblet cells: 127.8;Paneth cells: 226.4;Proximal enterocytes: 263.7;Undifferentiated cells: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 205.6" "Not detected" "Not detected" HPA022918 Approved Approved Cytosol No NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA022918: AB_2060743" "unprognostic (9.91e-2)" "unprognostic (4.77e-2)" "unprognostic (8.18e-2)" "unprognostic (5.75e-3)" "unprognostic (1.83e-1)" "unprognostic (2.31e-2)" "unprognostic (2.48e-1)" "unprognostic (5.22e-2)" "unprognostic (2.86e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.32e-2)" "prognostic favorable (6.29e-13)" "prognostic favorable (1.69e-5)" "unprognostic (1.36e-1)" "unprognostic (8.26e-2)" "unprognostic (3.34e-2)" 2.2 0.1 0.0 7.9 0.1 0.1 38.8 0.2 0.2 13.4 9.5 111.2 178.4 1.4 18.3 12.9 26.5 22.0 0.4 0.8 0.0 28.0 1.9 21.7 0.2 0.1 0.0 0.3 103.9 0.8 8.5 0.0 0.0 17.7 124.3 0.0 51.8 15.8 0.1 10.0 128.5 3.3 0.0 0.0 84.4 2.5 0.0 0.4 67.8 0.0 2.0 2.7 6.7 0.1 3.8 0.6 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 8.6 5.8 0.2 0.3 0.0 0.0 20.5 0.0 0.1 0.0 0.4 0.7 0.2 0.0 2.6 0.0 0.4 0.4 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 19.7 0.4 0.4 0.0 205.6 0.7 0.3 0.0 1.4 1.1 2.6 11.7 0.5 0.0 35.7 0.0 0.0 24.1 0.0 0.1 0.3 0.0 0.7 0.1 0.1 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 22.4 19.8 0.3 0.1 0.0 2.6 2.4 0.0 0.0 16.7 8.9 0.1 80.1 19.8 16.5 0.0 0.0 0.1 203.0 170.2 35.6 5.5 9.8 0.3 0.2 31.6 0.0 0.1 36.1 0.0 0.4 55.5 3.9 0.0 0.0 0.0 0.8 0.1 0.0 0.1 127.8 24.4 0.0 0.0 9.0 1.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 11.6 226.4 0.4 0.2 15.6 263.7 30.0 19.2 0.0 0.0 0.0 1.0 11.1 0.1 7.3 0.0 0.0 0.6 0.0 100.9 9.9 PRR18 MGC35308 ENSG00000176381 "Proline rich 18" Q8N4B5 6 166305300-166308448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 127.0" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 27.3" "Group enriched" "Detected in some" 5 "glioma: 3.1;liver cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 4.3;SH-SY5Y: 2.5" "Low region specificity" "Detected in all" HPA077250 Enhanced NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA077250: AB_2732336" "unprognostic (2.91e-1)" "unprognostic (7.18e-2)" "unprognostic (1.76e-1)" "unprognostic (2.39e-2)" "unprognostic (1.44e-1)" "unprognostic (9.65e-2)" "unprognostic (5.60e-3)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.44e-3)" "unprognostic (4.79e-3)" "unprognostic (2.43e-1)" "unprognostic (3.35e-3)" "unprognostic (9.49e-2)" "unprognostic (9.58e-2)" "unprognostic (1.07e-1)" 0.3 0.0 36.1 0.0 90.6 0.0 0.1 38.8 63.8 0.1 10.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 34.3 37.2 0.2 3.3 0.2 0.0 54.5 61.1 0.0 0.2 1.2 0.9 0.0 42.6 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 32.8 0.0 0.1 0.0 60.2 0.0 0.1 0.0 0.0 0.0 0.0 127.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 2.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.1 90.6 38.8 63.8 34.3 37.2 54.5 61.1 42.6 32.8 60.2 127.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.6 2.8 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 27.3 0.1 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR29 "C17orf72, DKFZp761M2312, FLJ11724" ENSG00000224383 "Proline rich 29" P0C7W0 17 63998351-64004305 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 58.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 57.4;Respiratory ciliated cells: 89.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5;REH: 3.7;TIME: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051264 Uncertain Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA051264: " "unprognostic (2.05e-2)" "unprognostic (6.46e-2)" "unprognostic (2.87e-2)" "unprognostic (2.92e-3)" "unprognostic (4.71e-3)" "unprognostic (3.22e-2)" "unprognostic (3.84e-1)" "unprognostic (3.95e-2)" "unprognostic (1.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.63e-3)" "unprognostic (5.76e-2)" "unprognostic (1.30e-3)" "unprognostic (6.48e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (9.98e-3)" 2.0 0.3 3.2 0.5 2.5 0.3 2.2 1.8 1.2 6.1 12.7 0.4 0.2 0.6 0.3 0.2 58.2 0.7 1.5 4.1 4.2 1.9 0.2 10.4 0.4 12.7 16.0 0.6 0.3 0.9 10.7 0.3 7.3 0.7 0.0 0.0 0.5 0.6 0.6 0.4 0.7 0.2 9.0 5.7 0.3 13.9 4.0 0.2 4.7 0.0 0.3 0.8 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.2 0.0 3.5 0.0 0.3 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.0 0.5 0.0 0.0 0.0 1.3 0.0 0.1 0.7 0.1 3.7 0.0 1.5 0.3 0.0 0.2 1.0 0.0 0.1 0.2 0.5 0.5 0.0 2.8 0.1 1.1 0.4 0.1 0.4 0.1 0.2 0.4 0.1 0.0 0.9 0.2 0.0 0.4 0.5 0.1 0.1 0.4 0.2 0.1 0.2 0.7 0.4 0.2 0.2 0.4 0.0 0.2 0.3 3.2 2.5 1.8 1.2 4.1 4.2 12.7 16.0 7.3 9.0 4.0 3.9 3.3 0.0 2.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.2 1.5 9.9 3.7 0.0 0.0 0.7 0.0 0.0 0.1 12.4 57.4 0.5 2.1 0.0 0.0 0.5 0.0 0.1 0.6 0.0 1.1 0.0 1.6 1.8 0.5 0.3 0.0 0.4 0.0 0.0 0.0 0.0 10.5 0.0 0.9 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 2.0 0.0 0.0 0.1 89.6 0.0 0.0 0.3 0.3 18.1 1.4 0.0 0.0 0.3 0.7 3.5 0.0 0.1 PRR5 "FLJ20185k, PP610, Protor-1" ENSG00000186654 "Proline rich 5" P85299 22 44668547-44737681 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 91.3;NK-cells: 77.2;Proximal tubular cells: 55.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "monocytes: 19.1;T-cells: 28.6" "Cell line enhanced" "Detected in many" "U-266/70: 99.2;U-266/84: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054072 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054072: AB_2682369" "unprognostic (2.63e-2)" "unprognostic (6.63e-3)" "unprognostic (2.61e-2)" "prognostic favorable (2.47e-5)" "unprognostic (1.83e-2)" "unprognostic (3.99e-2)" "unprognostic (7.52e-2)" "unprognostic (1.37e-1)" "unprognostic (8.98e-2)" "unprognostic (5.13e-2)" "unprognostic (1.34e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-1)" "unprognostic (2.48e-3)" "unprognostic (1.55e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" 16.2 2.4 7.2 3.2 7.7 7.2 12.2 5.9 11.3 8.4 11.9 6.0 8.6 3.8 2.1 7.6 4.3 2.9 3.5 7.9 9.7 11.5 18.5 3.5 3.9 8.1 8.2 4.0 6.2 2.3 16.1 4.5 8.5 7.9 2.4 0.4 5.7 3.8 0.8 7.4 9.4 1.1 5.9 20.5 5.2 5.1 10.5 2.3 4.5 1.2 2.5 6.9 7.1 5.8 8.1 9.6 2.0 6.8 0.2 0.3 25.0 7.0 6.2 4.2 3.4 24.4 3.4 0.0 5.2 8.2 4.9 7.2 2.1 7.1 0.7 0.2 19.9 15.9 1.3 28.5 5.8 2.9 5.8 2.9 7.9 0.4 2.2 1.0 0.2 3.7 10.1 0.5 0.9 21.4 1.1 4.6 1.3 11.4 1.4 0.7 4.5 14.5 1.4 3.8 7.0 1.0 1.9 11.4 9.5 5.5 5.3 2.8 0.0 0.1 11.0 1.0 0.1 99.2 31.3 0.2 0.0 6.4 0.8 0.5 0.3 0.1 24.8 3.4 28.6 1.6 8.3 18.8 0.7 0.9 3.5 13.0 0.6 5.6 19.1 0.4 14.8 6.8 7.2 7.7 5.9 11.3 7.9 9.7 8.1 8.2 8.5 5.9 10.5 5.8 6.0 0.0 3.9 11.4 9.2 8.3 12.0 2.1 4.0 0.7 13.6 13.2 2.0 10.0 2.3 5.5 0.0 32.1 50.3 20.5 5.9 5.2 0.5 4.4 5.4 12.5 9.6 91.3 2.0 7.9 3.3 23.2 8.2 4.7 7.6 5.4 21.4 19.9 32.1 0.0 1.8 22.8 2.0 13.5 8.2 0.5 5.3 7.7 8.8 3.7 3.0 6.0 77.2 1.0 0.2 8.4 7.6 3.8 29.0 24.2 50.9 55.2 1.4 1.5 0.0 11.4 5.3 0.3 20.4 8.0 8.5 44.1 37.1 51.8 25.5 13.5 PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" 8.6 3.7 12.3 2.1 24.9 0.2 5.2 21.6 19.7 4.4 4.7 4.0 2.9 4.3 1.5 4.1 2.6 8.8 6.4 12.9 15.9 10.5 7.9 5.5 1.7 26.7 21.3 4.2 1.6 1.2 1.4 8.1 25.3 3.4 4.1 1.5 2.9 7.8 15.9 2.2 3.0 5.4 18.4 2.9 2.4 1.5 18.4 1.5 8.3 7.8 1.0 5.6 3.8 39.4 32.3 7.2 5.6 5.6 18.7 15.4 2.4 14.1 17.6 4.7 8.2 17.1 20.2 0.0 21.8 10.4 8.9 10.7 15.6 10.0 8.3 0.1 5.2 5.2 7.7 5.7 22.6 0.0 7.2 23.2 8.1 9.1 7.7 9.4 24.8 0.0 2.6 0.1 16.5 2.4 0.1 0.1 6.8 5.1 13.4 0.0 13.1 0.0 79.2 1.7 0.0 0.1 9.7 15.6 6.1 15.3 0.1 3.5 17.6 7.5 4.2 14.2 4.1 0.0 0.1 0.0 7.3 0.0 7.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.3 24.9 21.6 19.7 12.9 15.9 26.7 21.3 25.3 18.4 18.4 39.4 29.7 6.4 4.2 15.7 0.0 11.3 4.8 7.6 5.2 2.2 5.3 5.3 8.1 15.7 2.7 33.1 0.0 7.0 0.2 7.6 7.9 6.8 0.7 3.3 12.9 18.4 3.0 0.0 23.3 3.1 14.9 9.6 4.6 9.2 1.3 3.9 17.9 16.3 4.8 18.5 10.8 5.7 14.2 4.1 5.3 0.4 4.7 1.4 3.6 31.9 0.8 2.2 0.0 12.5 229.8 18.7 7.5 2.6 0.0 9.1 4.3 9.4 2.9 0.5 6.6 8.3 8.4 2.5 4.2 5.2 6.3 10.4 0.4 3.5 4.8 8.1 PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 28.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 47.2;Proximal enterocytes: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.9;OE19: 18.0;RT4: 11.7;SK-BR-3: 13.3;T-47d: 14.4;U-266/84: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA010702: AB_1079693" "unprognostic (2.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (5.60e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "prognostic favorable (3.82e-9)" "unprognostic (4.89e-2)" "unprognostic (1.46e-1)" "unprognostic (6.58e-3)" "unprognostic (3.68e-2)" 1.2 0.4 0.9 1.2 0.9 0.1 7.0 1.3 2.6 4.9 0.6 8.4 12.0 1.5 12.9 13.5 4.9 4.3 1.2 0.9 1.0 11.8 6.4 3.9 0.9 1.2 0.9 0.3 13.1 28.4 15.6 2.1 1.1 6.2 7.7 0.1 11.3 9.0 0.9 12.9 11.0 1.1 0.9 1.0 9.8 0.9 1.1 2.3 13.4 0.1 3.9 6.7 5.5 1.0 11.1 0.4 0.3 0.9 1.3 0.0 4.6 0.2 0.0 0.4 0.4 2.2 14.9 0.7 1.6 0.1 0.3 8.5 0.3 8.5 0.4 1.1 1.2 0.5 0.8 0.7 0.9 0.4 1.1 0.9 7.4 0.3 0.3 0.7 3.4 0.9 0.2 0.8 0.0 2.4 0.2 0.7 0.6 18.0 1.4 0.2 0.3 8.7 6.5 11.7 2.4 0.3 1.3 13.3 0.1 1.0 14.4 0.2 0.6 0.8 0.7 0.4 0.1 5.1 18.7 0.5 0.2 0.3 0.4 0.0 0.2 0.1 0.4 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.2 0.2 0.5 0.0 0.2 1.2 0.2 0.1 0.9 0.9 1.3 2.6 0.9 1.0 1.2 0.9 1.1 0.9 1.1 1.0 6.4 6.4 13.4 0.7 3.4 4.1 11.6 20.2 29.6 2.2 21.5 22.6 0.9 8.6 14.2 12.9 2.1 13.0 4.1 47.2 3.9 31.9 0.7 10.8 4.1 6.4 16.2 1.3 0.5 33.2 6.5 1.6 16.8 16.1 2.5 2.3 1.1 6.8 2.3 5.0 0.4 18.0 8.2 1.9 1.2 0.4 0.3 3.3 1.8 1.9 8.2 0.9 2.1 2.0 0.4 27.4 29.4 0.0 4.4 14.5 46.3 15.5 8.8 4.1 0.0 0.8 3.9 1.9 2.1 23.3 4.7 12.7 4.1 4.6 20.7 14.6 PRRG4 TMG4 ENSG00000135378 "Proline rich and Gla domain 4" Q9BZD6 11 32829927-32858120 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 124.3;Basal squamous epithelial cells: 145.1;Prostatic glandular cells: 153.9;Squamous epithelial cells: 141.8;Suprabasal keratinocytes: 141.5;Urothelial cells: 167.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "neutrophil: 11.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.9" "Cell line enhanced" "Detected in many" "HaCaT: 52.7;hTCEpi: 28.0;SK-BR-3: 22.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009040, HPA024566" Uncertain Approved "Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA009040: AB_1079694, HPA024566: AB_2237712" "unprognostic (3.30e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (6.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.45e-2)" "unprognostic (2.06e-1)" "unprognostic (4.13e-1)" "unprognostic (3.24e-2)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (2.26e-3)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (2.41e-1)" "unprognostic (1.26e-2)" 1.1 1.6 0.7 2.0 0.9 4.6 7.2 0.7 0.8 7.5 2.1 6.9 7.5 1.4 6.1 23.4 5.4 3.4 1.3 0.7 1.5 13.3 22.6 6.4 1.1 1.1 0.9 0.3 3.9 2.9 2.8 5.8 1.1 6.3 6.3 0.2 10.0 6.0 1.1 20.8 7.4 0.9 0.7 3.0 5.4 0.5 1.0 3.6 5.5 1.4 6.6 6.8 13.7 1.3 13.2 0.4 0.1 0.1 0.3 0.0 5.4 0.1 6.5 1.5 2.6 6.2 12.7 0.1 0.4 0.0 3.3 52.7 1.3 3.2 0.4 0.4 8.7 2.7 1.8 0.4 0.0 0.9 2.4 0.4 28.0 0.5 0.1 2.2 0.0 0.0 0.0 0.7 0.5 5.9 1.1 6.0 0.6 10.7 1.5 0.1 0.0 1.6 9.6 16.5 1.8 0.1 8.8 22.0 2.8 1.6 16.0 12.8 0.1 0.6 0.8 2.9 1.3 5.8 4.3 0.1 1.6 7.5 2.5 0.8 2.3 0.1 0.1 0.8 0.1 0.1 0.1 0.1 0.5 0.2 0.1 0.1 11.9 0.2 0.8 0.2 0.1 0.5 0.7 0.9 0.7 0.8 0.7 1.5 1.1 0.9 1.1 0.7 1.0 1.3 4.2 28.9 23.0 1.0 2.8 124.3 92.5 53.6 145.1 0.1 43.0 21.1 1.0 95.8 33.9 47.8 0.0 24.4 1.7 46.8 7.9 31.5 0.7 75.5 7.4 10.2 13.8 2.5 0.3 36.3 16.8 3.6 25.0 81.9 0.0 6.0 8.9 57.1 8.1 1.7 0.3 34.7 24.4 50.0 15.4 0.3 0.3 12.6 12.4 4.7 40.2 0.1 0.0 1.0 0.1 26.4 19.5 1.5 6.9 153.9 48.3 21.4 51.1 0.2 6.6 2.5 8.8 2.4 4.1 141.8 141.5 82.0 2.6 0.2 47.0 167.4 PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361685 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 16.3;bone marrow: 57.7" "Group enriched" "Detected in some" 7 "Bipolar cells: 4.8;Horizontal cells: 10.1;Inhibitory neurons: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 225.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" 16.3 1.3 3.2 0.4 2.7 57.7 8.5 3.2 2.9 2.5 0.7 1.3 0.1 0.5 0.0 2.7 1.1 0.7 1.5 2.0 6.3 0.1 0.4 0.9 0.1 4.7 4.8 1.1 0.3 0.3 0.2 0.0 4.0 0.4 0.2 1.0 1.1 0.8 4.5 2.3 1.2 0.4 3.6 2.1 2.1 0.4 5.1 0.6 0.5 4.5 0.0 0.5 3.0 2.1 0.0 0.1 0.3 0.5 1.3 0.1 3.8 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.2 8.8 0.1 1.3 0.0 0.0 0.1 0.0 0.0 12.8 0.0 0.0 0.0 1.0 2.6 46.6 1.2 0.0 0.1 12.9 0.6 1.0 0.0 0.1 0.5 225.3 0.4 0.2 0.3 1.5 0.1 6.1 0.0 0.0 1.0 0.5 0.1 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.7 3.2 2.9 2.0 6.3 4.7 4.8 4.0 3.6 5.1 2.1 0.4 0.0 0.0 1.0 0.0 0.6 0.1 0.2 0.6 4.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.2 10.1 12.6 0.0 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.8 1.2 0.3 0.3 0.1 0.0 0.0 0.1 PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 405.6" "Group enriched" "Detected in some" 7 "Adipocytes: 161.4;Cardiomyocytes: 161.5;Hofbauer cells: 75.1;Smooth muscle cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 166.0" "Lineage enriched" "Detected in all" 11 "dendritic cells: 166.0" "Cell line enhanced" "Detected in many" "ASC diff: 947.9;HaCaT: 276.4;HUVEC TERT2: 436.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" 405.6 25.1 112.4 15.9 110.4 3.6 210.2 97.4 119.8 92.0 122.6 51.8 84.0 52.5 212.8 83.9 30.9 30.8 76.3 121.8 104.3 110.9 197.3 20.9 18.0 108.2 111.3 30.7 66.0 69.0 59.1 45.2 108.5 70.4 43.2 42.9 50.6 44.3 49.7 81.1 59.8 19.9 103.1 12.3 24.8 51.5 131.1 34.7 55.1 75.8 26.9 71.4 51.9 101.5 26.0 62.9 105.3 0.4 947.9 0.1 7.2 4.0 22.0 2.0 0.5 60.1 76.3 16.6 82.1 0.3 47.1 276.4 9.5 10.9 0.5 1.1 17.6 32.5 23.8 89.0 91.9 0.3 9.0 71.1 20.2 6.7 0.3 250.1 436.7 95.1 26.9 0.6 0.0 89.6 41.9 4.7 51.2 39.1 0.3 117.5 48.5 0.8 223.1 106.2 107.6 76.6 11.0 147.7 168.4 78.9 66.2 46.2 119.1 0.6 1.0 0.5 0.6 9.3 22.0 0.4 66.0 0.6 7.6 1.3 3.5 11.6 6.6 0.8 5.1 15.8 3.7 5.5 3.3 11.1 13.4 13.9 2.2 6.2 0.2 166.0 0.2 4.8 112.4 110.4 97.4 119.8 121.8 104.3 108.2 111.3 108.5 103.1 131.1 101.5 161.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.5 0.0 0.0 0.0 0.0 13.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 7.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.0 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome 20S subunit alpha 7" O14818 20 62136733-62143440 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 753.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266" Approved NA NA 22000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "CAB046007: AB_11128404, CAB046008: AB_2171861, HPA047266: AB_2680006" "unprognostic (1.49e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-1)" "unprognostic (6.57e-3)" "prognostic unfavorable (2.54e-5)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (7.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-2)" "unprognostic (1.98e-2)" 223.2 200.1 127.6 148.5 132.0 260.4 198.0 136.9 146.2 134.6 127.1 180.3 132.2 163.4 102.9 191.0 140.5 91.3 266.2 131.9 137.0 168.9 214.0 170.3 164.9 134.0 131.7 134.4 140.2 114.1 104.1 115.0 136.7 117.8 108.0 54.5 129.2 104.2 753.9 136.6 151.3 117.1 134.7 163.3 152.9 61.3 136.4 188.0 121.9 375.3 155.4 168.2 141.3 143.7 532.8 674.6 390.9 419.4 357.2 277.8 345.0 398.3 343.6 1024.7 428.8 1785.8 504.0 438.2 926.2 421.0 644.1 627.2 371.9 752.5 497.0 261.0 261.1 1009.7 641.9 913.2 454.0 434.3 570.4 297.9 602.0 525.1 454.5 248.8 509.2 436.1 439.2 419.2 441.8 568.6 696.1 673.6 332.5 595.0 859.8 476.9 753.5 482.6 385.3 515.4 526.2 321.6 625.9 777.1 701.9 252.7 468.3 643.3 416.1 898.9 725.4 473.3 631.1 286.9 483.9 531.2 626.7 327.7 536.1 754.4 682.6 801.5 536.5 692.6 458.2 579.3 533.3 531.4 632.2 522.7 415.1 427.3 582.2 421.7 720.3 676.3 723.4 1131.2 127.6 132.0 136.9 146.2 131.9 137.0 134.0 131.7 136.7 134.7 136.4 143.7 402.9 211.5 180.8 20.9 252.3 374.5 350.6 616.4 167.4 127.5 223.0 296.4 304.9 327.5 369.2 257.5 73.0 666.2 309.5 375.2 498.9 581.9 355.5 290.2 345.4 397.3 232.0 439.4 19.2 727.7 775.7 321.9 132.0 276.5 251.4 304.7 335.5 787.5 807.0 82.4 18.4 325.6 453.7 435.7 453.1 211.0 334.6 414.8 368.2 18.7 598.4 219.3 377.9 15.1 28.9 663.3 386.4 293.8 234.5 639.7 455.1 759.6 288.8 122.5 230.1 237.0 659.7 81.4 126.3 291.9 309.3 852.6 310.4 410.0 386.9 438.7 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 2700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favorable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favorable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 62.7 76.9 3.3 11.2 3.4 9.8 56.5 3.3 7.3 42.7 3.4 79.9 12.9 41.3 3.2 59.5 41.6 5.8 34.2 3.4 3.5 63.7 99.2 78.2 18.2 4.3 3.4 32.1 29.5 8.2 26.6 4.4 3.7 45.2 20.4 0.7 44.2 6.4 14.4 58.0 93.9 8.9 4.0 150.4 57.0 5.9 3.6 13.5 40.8 0.1 17.2 41.3 48.1 4.1 15.1 3.9 0.3 0.0 5.1 13.1 11.2 4.9 22.9 29.1 39.3 0.0 20.9 45.7 9.4 10.5 25.5 8.1 6.8 16.6 8.0 19.2 0.0 27.6 5.9 0.3 30.3 5.2 7.5 14.9 10.3 12.9 6.8 1.9 18.1 11.8 1.1 8.1 6.1 0.1 12.9 11.7 0.1 0.0 7.3 29.3 1.3 24.1 21.3 4.9 0.8 0.2 8.6 10.4 8.5 0.1 7.0 41.0 4.3 8.8 7.6 7.8 0.6 21.0 15.9 11.2 2.2 27.7 9.0 56.8 70.3 94.6 58.1 88.0 51.2 73.4 49.1 61.1 67.5 71.1 34.8 49.6 90.2 63.0 78.2 58.5 81.2 156.0 3.3 3.4 3.3 7.3 3.4 3.5 4.3 3.4 3.7 4.0 3.6 4.1 237.0 38.5 55.8 2.9 162.0 84.4 64.1 183.7 54.7 1.8 85.3 92.5 8.7 71.4 103.2 62.5 0.0 2.7 211.2 219.9 86.1 219.4 0.6 63.2 74.9 158.5 65.7 45.0 0.1 247.6 18.3 60.7 93.8 81.5 50.7 51.4 114.5 75.0 165.9 6.7 0.5 243.8 120.1 143.5 94.9 1.9 39.1 128.2 56.9 10.3 214.3 39.9 279.1 3.0 0.7 179.6 287.9 30.5 153.2 100.1 319.8 78.9 103.2 3.0 39.5 33.2 56.8 0.4 1.2 60.5 79.6 2.7 181.6 110.9 222.6 121.6 PSMD8 "HIP6, HYPF, Nin1p, p31, Rpn12, S14" ENSG00000099341 "Proteasome 26S subunit, non-ATPase 8" P48556 19 38374550-38383824 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 708.9" "Cell type enhanced" "Detected in all" "Late spermatids: 1164.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006702, CAB021101" Supported Approved "Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nuclear speckles" "CAB021101: AB_10061018, HPA006702: AB_1079710" "unprognostic (9.50e-2)" "unprognostic (7.02e-2)" "unprognostic (1.70e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.59e-1)" "unprognostic (5.54e-3)" "unprognostic (1.94e-3)" "unprognostic (5.03e-2)" "unprognostic (2.85e-2)" "unprognostic (1.73e-2)" "unprognostic (4.61e-1)" "unprognostic (8.79e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.28e-1)" "unprognostic (2.08e-2)" "unprognostic (2.58e-3)" "unprognostic (4.84e-2)" 224.8 130.8 102.3 78.0 109.6 118.8 184.9 104.1 114.8 109.6 97.6 111.8 98.1 115.8 119.4 156.6 104.0 69.2 361.8 114.4 117.5 122.4 143.0 114.9 90.8 109.2 104.3 82.1 117.3 150.2 111.1 101.1 121.9 107.1 98.9 60.6 118.8 84.5 708.9 178.4 106.4 105.2 105.4 99.4 117.6 145.8 112.6 120.3 91.2 361.1 109.9 106.3 111.0 112.6 337.3 522.7 202.2 231.9 322.0 256.9 105.9 238.7 322.9 358.9 372.3 362.0 196.3 234.7 242.8 320.0 220.1 114.1 341.7 296.8 321.6 389.8 225.6 256.1 159.6 226.4 415.1 260.8 217.9 261.2 290.8 309.7 408.8 197.3 286.5 279.9 324.9 255.7 400.6 332.8 247.6 146.1 157.8 492.8 282.7 254.7 324.6 187.4 255.7 275.1 210.8 214.3 247.3 315.7 233.8 187.1 165.3 242.0 212.7 272.1 251.5 289.0 355.8 257.2 322.4 318.0 410.1 264.8 310.1 169.0 239.5 132.6 188.2 265.1 160.0 172.8 162.0 181.0 263.1 173.6 133.0 129.5 89.0 182.7 319.8 183.2 295.2 352.3 102.3 109.6 104.1 114.8 114.4 117.5 109.2 104.3 121.9 105.4 112.6 112.6 137.4 67.3 67.9 8.1 122.9 206.0 224.5 293.5 80.2 102.6 116.3 141.0 263.8 81.5 158.8 80.9 54.2 367.2 128.2 194.6 348.3 276.0 422.3 137.2 158.2 127.0 146.0 129.2 14.7 267.4 327.5 146.8 71.4 122.5 93.8 146.9 81.4 123.1 296.9 77.4 15.4 183.9 219.7 93.1 169.5 1164.7 118.4 126.9 199.3 10.3 224.0 179.8 143.2 8.0 19.8 296.8 181.2 117.8 178.9 255.0 305.7 332.4 128.5 120.4 151.2 106.6 221.1 305.1 135.4 120.3 212.3 570.3 133.0 201.0 182.5 218.7 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863625-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 64.0 25.4 17.8 18.6 19.3 12.9 47.6 34.5 23.4 54.8 15.6 28.1 12.9 27.4 18.6 28.3 35.2 15.6 29.7 20.4 18.4 22.6 39.2 39.5 21.4 16.6 17.8 28.0 33.2 11.9 17.3 30.5 16.4 26.3 14.6 30.0 19.6 16.5 23.7 25.9 24.5 22.2 14.5 40.0 25.6 28.2 19.7 31.8 26.1 14.0 16.5 28.1 38.4 17.6 23.5 10.8 12.3 11.2 28.5 19.7 10.9 12.5 28.0 14.5 20.4 10.9 28.0 28.1 8.0 20.9 8.3 14.1 16.6 14.3 22.8 14.1 4.7 9.3 28.5 13.8 30.1 31.9 15.3 13.5 38.7 18.0 23.7 60.3 20.8 17.7 7.0 72.6 13.5 18.1 17.8 56.3 4.6 19.9 0.0 27.6 6.4 20.8 22.9 13.4 4.5 19.9 16.6 7.9 23.0 9.7 21.9 45.2 17.9 44.6 10.8 18.3 10.1 23.9 32.9 30.7 14.6 29.2 2.9 21.3 14.2 25.8 6.8 21.8 7.2 7.9 7.2 6.6 10.3 6.8 8.3 8.3 60.5 8.9 15.6 8.2 7.0 4.5 17.8 19.3 34.5 23.4 20.4 18.4 16.6 17.8 16.4 14.5 19.7 17.6 67.2 35.3 63.3 83.6 48.3 56.1 57.4 31.5 47.3 113.0 49.4 41.9 46.5 57.2 31.2 29.5 39.6 25.8 64.4 57.7 33.2 24.7 70.1 40.0 114.5 56.0 31.2 52.0 141.0 30.0 62.2 79.3 39.8 33.6 25.4 39.6 53.9 64.1 35.0 45.4 132.4 44.7 12.2 206.1 97.2 92.1 56.8 105.2 62.2 196.8 101.5 61.6 44.3 139.2 95.7 30.6 39.7 54.5 39.3 45.1 50.1 38.0 31.2 61.2 92.1 66.4 170.7 33.5 25.4 45.2 60.1 57.3 46.3 44.7 46.1 64.0 PTGER3 "EP3, lnc003875" ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047808 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 95.2;kidney: 81.2;smooth muscle: 68.0" "Group enriched" "Detected in many" 7 "Distal tubular cells: 225.0;Langerhans cells: 79.8" "Group enriched" "Detected in some" 7 "breast cancer: 4.1;renal cancer: 9.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 59 "basophil: 43.3" "Lineage enriched" "Detected in single" 59 "granulocytes: 43.3" "Cell line enhanced" "Detected in some" "ASC diff: 28.6;HAP1: 20.9;HDLM-2: 32.8;HEL: 15.6;T-47d: 72.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "HPA010689: AB_1855883" "unprognostic (1.53e-3)" "unprognostic (3.48e-1)" "unprognostic (1.11e-1)" "unprognostic (3.86e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (4.80e-2)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (8.83e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-4)" 54.5 6.7 7.1 5.0 4.3 0.2 28.6 0.0 8.5 4.7 10.4 13.9 1.2 95.2 3.7 3.9 10.1 8.9 1.6 4.7 10.9 81.2 0.3 1.0 1.3 5.6 0.6 1.7 6.6 0.9 0.6 0.6 3.2 3.0 2.3 0.7 11.9 7.9 0.4 13.8 3.7 68.0 2.4 0.3 22.4 1.0 4.7 0.9 1.0 1.4 1.4 6.6 6.1 1.1 0.0 0.0 0.0 0.0 28.6 0.7 0.1 0.7 0.0 0.1 0.7 0.0 0.0 0.0 0.0 3.5 0.0 0.0 20.9 0.0 0.1 32.8 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.1 0.0 0.3 0.0 0.2 72.5 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.1 7.2 0.0 43.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 7.1 4.3 0.0 8.5 4.7 10.9 5.6 0.6 3.2 2.4 4.7 1.1 6.9 0.0 0.5 0.0 0.0 5.0 0.2 0.0 0.0 1.6 13.7 6.1 1.8 1.5 0.0 20.2 0.0 0.0 0.2 0.4 225.0 3.0 1.6 0.6 4.6 1.7 2.4 0.0 2.2 0.0 2.4 12.2 1.5 1.2 9.5 0.0 0.7 0.0 0.1 3.3 3.4 1.0 12.2 0.0 79.8 1.0 1.2 3.2 8.8 0.0 0.6 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.1 1.3 0.1 7.2 0.0 0.2 6.6 0.5 11.7 0.1 0.1 0.1 7.5 0.1 1.2 6.2 0.0 0.2 PTGFRN "CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6" ENSG00000134247 "Prostaglandin F2 receptor inhibitor" Q9P2B2 1 116909916-116990353 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 66.2;Cardiomyocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-87 MG: 146.8;WM-115: 111.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017074 Approved NA NA 340000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA017074: AB_1855888" "unprognostic (1.18e-1)" "unprognostic (2.11e-3)" "unprognostic (3.03e-1)" "unprognostic (8.58e-2)" "unprognostic (3.20e-1)" "unprognostic (2.91e-2)" "unprognostic (1.48e-3)" "unprognostic (3.39e-2)" "unprognostic (1.76e-2)" "unprognostic (7.28e-2)" "unprognostic (2.77e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "unprognostic (4.15e-2)" 11.6 21.1 3.2 10.1 3.5 0.0 10.6 3.3 4.8 14.9 8.3 40.6 11.3 31.2 10.6 21.2 23.9 17.2 48.8 3.3 2.6 4.0 6.6 6.6 2.5 2.8 4.5 15.9 13.3 6.3 2.9 5.0 2.2 18.0 21.7 1.4 18.5 23.6 2.9 17.8 14.0 46.6 4.6 3.1 10.5 5.3 4.1 5.3 6.9 3.9 6.2 20.1 15.1 3.2 40.0 10.3 18.4 42.8 3.2 8.3 2.6 2.8 4.4 15.4 5.8 7.2 8.7 0.0 35.7 10.6 12.7 69.7 41.4 74.4 9.7 0.4 25.1 2.9 24.0 11.1 1.1 0.1 3.9 37.3 66.0 2.0 36.4 21.9 30.0 4.2 16.5 0.2 23.5 50.9 0.0 5.5 21.5 3.3 0.1 0.0 100.6 0.2 51.3 32.4 9.0 20.8 80.0 55.9 22.9 32.1 48.8 12.3 77.6 22.4 33.2 37.2 25.1 0.0 0.1 0.1 146.8 0.0 111.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 3.5 3.3 4.8 3.3 2.6 2.8 4.5 2.2 4.6 4.1 3.2 2.3 3.2 5.9 15.0 0.5 66.2 13.4 25.6 22.2 6.5 10.9 11.9 79.4 10.0 12.2 3.7 0.0 0.8 0.3 20.6 1.9 31.2 4.8 10.2 19.3 12.1 13.9 0.0 13.6 31.8 5.5 32.0 10.7 16.9 0.0 22.1 3.9 11.1 4.4 0.0 7.4 18.2 14.2 8.8 9.7 6.3 19.3 4.7 8.8 3.7 3.1 1.2 0.0 31.2 0.9 27.9 11.1 30.1 0.0 15.1 15.8 1.2 13.6 0.2 19.7 48.5 12.5 0.8 5.2 20.3 45.3 0.8 1.4 28.3 26.3 17.4 PTH1R "PTHR, PTHR1" ENSG00000160801 "Parathyroid hormone 1 receptor" Q03431 3 46877721-46903799 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 586.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Extravillous trophoblasts: 60.8;Proximal tubular cells: 324.8;Sertoli cells: 138.1" "Group enriched" "Detected in many" 4 "renal cancer: 18.8;testis cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "RPTEC TERT1: 116.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075879 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA075879: " "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-5)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (5.02e-2)" "unprognostic (3.84e-3)" "unprognostic (5.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (7.51e-2)" "unprognostic (8.44e-2)" "prognostic favorable (6.79e-6)" "unprognostic (4.22e-3)" "unprognostic (1.50e-1)" "unprognostic (1.35e-4)" "unprognostic (6.62e-3)" 32.5 72.2 45.0 1.1 43.8 0.0 20.2 45.7 60.8 43.8 38.0 10.3 1.2 19.1 2.7 3.7 20.3 3.5 33.0 42.6 43.5 586.8 84.6 25.6 2.4 46.5 44.9 22.2 7.6 1.2 5.9 16.0 46.7 12.4 0.6 0.7 2.7 3.5 7.7 9.8 9.6 2.6 44.5 54.4 7.6 10.3 46.2 0.4 6.5 2.2 0.4 12.3 20.3 43.3 0.0 0.2 0.2 0.2 15.9 1.9 0.2 0.4 0.2 0.3 0.2 0.4 0.0 0.0 1.6 0.1 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 15.5 0.0 0.1 0.0 0.2 0.1 0.0 0.0 2.6 0.1 0.1 0.0 0.3 2.1 0.0 0.1 0.1 5.3 0.0 116.9 0.0 0.2 0.7 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.0 43.8 45.7 60.8 42.6 43.5 46.5 44.9 46.7 44.5 46.2 43.3 4.6 0.0 0.0 17.3 2.5 1.3 0.1 0.0 0.6 1.5 2.9 0.4 5.0 2.8 0.0 33.1 0.0 0.6 0.1 0.0 95.9 0.0 11.6 0.6 20.5 4.1 0.0 8.0 1.6 0.5 60.8 9.6 0.0 0.6 0.0 0.1 17.2 0.7 2.0 1.7 2.8 0.0 0.0 1.3 2.8 32.5 5.9 2.1 0.0 1.9 0.0 3.2 0.0 1.0 0.3 0.3 0.0 2.2 0.0 0.0 0.0 324.8 0.0 1.7 138.1 6.5 21.7 0.9 2.7 0.0 0.9 0.8 2.0 0.3 0.0 0.1 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Group enriched" "Detected in many" 4 "B-cells: 67.4;dendritic cells: 176.0;NK-cells: 108.1;Plasma cells: 79.6;T-cells: 151.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 69.3;HL-60: 27.7;U-266/70: 29.2;U-698: 37.5;U-937: 28.4" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 2.0 1.5 0.2 11.5 0.2 38.0 2.3 0.4 0.5 1.8 0.6 4.0 6.4 1.0 1.1 1.7 0.9 4.8 0.6 0.1 0.2 0.6 2.0 7.5 20.3 0.5 0.2 0.6 1.3 0.3 0.3 0.8 0.4 1.0 4.3 0.4 1.3 0.6 0.3 0.9 8.6 1.6 0.2 13.2 5.2 1.4 0.6 20.0 0.7 0.2 13.5 4.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.9 0.4 0.0 0.7 0.0 0.4 69.3 0.1 0.2 0.0 0.0 0.0 0.1 0.5 6.5 0.0 10.0 0.0 0.0 0.2 27.7 21.1 5.7 0.0 2.8 0.2 5.1 10.6 17.2 0.1 15.7 10.3 0.2 20.1 15.7 0.0 0.1 0.0 1.2 6.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 5.0 16.0 0.3 0.4 0.5 29.2 6.6 37.5 11.1 28.4 0.1 15.8 4.8 25.0 17.0 1.3 20.1 9.9 8.4 13.6 8.7 7.4 5.0 12.1 2.4 11.0 0.6 5.2 14.5 7.3 0.2 0.2 0.4 0.5 0.1 0.2 0.5 0.2 0.4 0.2 0.6 0.8 2.2 0.0 6.5 0.7 67.4 2.5 0.2 0.0 1.2 0.7 2.2 2.4 0.8 0.0 0.2 1.8 2.1 0.1 176.0 2.2 0.0 0.1 0.4 0.7 0.5 1.7 0.0 16.6 3.2 0.6 0.3 2.2 12.8 1.0 27.8 0.0 0.4 0.5 7.1 0.0 2.5 1.2 0.0 17.3 26.8 1.0 0.0 26.4 3.6 2.8 14.4 0.0 108.1 0.0 1.7 0.5 0.8 0.0 79.6 0.3 4.3 0.1 2.2 0.5 13.1 0.6 1.4 0.4 0.6 0.3 2.7 0.1 151.2 0.0 2.2 0.3 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in many" "B-cells: 46.8;dendritic cells: 112.7;granulocytes: 140.7;NK-cells: 99.9;Plasma cells: 63.9;T-cells: 127.2;Theca cells: 54.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 9.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 24.9;NK-cells: 14.9;T-cells: 14.0" "Cell line enhanced" "Detected in some" "HEL: 54.1;HL-60: 118.6;HMC-1: 150.8;NB-4: 51.4;THP-1: 53.7;U-937: 84.0" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in many" 8 "basal ganglia: 13.3" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 1.3 4.2 0.6 10.2 9.8 39.7 0.7 1.0 1.8 0.8 0.5 2.2 4.5 1.1 0.0 1.5 0.6 3.2 0.5 0.6 1.2 1.3 1.1 2.5 20.8 2.3 1.5 0.3 0.4 0.1 0.3 0.5 1.8 0.8 2.7 0.0 1.3 0.6 0.1 1.2 5.6 1.5 1.4 9.9 2.4 8.3 2.9 31.1 0.8 0.5 20.8 3.2 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.6 0.0 54.1 0.0 0.0 0.0 118.6 150.8 0.0 0.0 0.0 0.0 0.0 0.1 40.0 2.3 5.0 0.0 0.0 16.3 51.4 0.0 0.0 0.0 2.4 0.0 39.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 53.7 0.3 0.0 0.5 0.0 0.1 22.8 6.3 33.7 0.1 84.0 0.1 17.9 1.5 24.9 13.7 1.5 12.5 2.6 9.2 14.0 2.9 3.2 6.7 8.2 9.9 14.9 0.6 3.8 12.8 4.5 0.6 9.8 1.0 1.8 0.6 1.2 2.3 1.5 1.8 1.4 2.9 2.5 3.2 3.2 5.1 3.3 46.8 2.3 1.3 0.1 0.0 2.7 1.5 1.8 0.7 1.5 0.7 0.0 0.0 0.5 112.7 0.5 0.0 0.5 0.6 0.9 0.8 5.6 0.0 35.5 0.7 0.0 0.2 2.2 1.5 0.7 140.7 6.7 3.6 0.4 15.4 0.0 0.7 0.1 0.0 11.2 31.2 2.4 5.3 21.3 8.8 1.0 10.4 3.8 99.9 1.0 4.6 0.1 0.1 2.2 63.9 0.6 0.2 0.7 0.1 3.7 0.0 0.9 1.1 0.8 0.7 0.5 2.4 0.8 127.2 54.6 0.5 0.6 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 208.6;lymphoid tissue: 329.9" "Cell type enhanced" "Detected in many" "B-cells: 525.2;dendritic cells: 1026.4;Macrophages: 534.1;monocytes: 554.9;NK-cells: 769.3;Plasma cells: 474.2;T-cells: 1049.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 209.9;HEL: 118.0;HL-60: 108.1;JURKAT: 266.4;MOLT-4: 161.1;THP-1: 87.0;U-266/70: 93.7;U-266/84: 91.2;U-698: 123.4;U-937: 94.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 24000000 "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 32.8 11.6 3.8 248.5 3.3 208.6 13.9 4.4 4.3 14.9 6.9 26.4 27.4 11.3 5.6 15.1 8.4 45.7 7.3 3.5 5.6 7.0 29.6 68.6 329.9 12.9 8.6 5.7 5.6 4.0 2.9 23.5 11.5 11.6 30.5 2.0 13.8 6.6 4.6 5.7 42.9 25.3 7.9 202.5 37.9 5.5 6.9 306.9 7.0 7.6 251.2 62.1 5.2 14.7 0.4 0.0 0.2 0.2 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.1 209.9 0.3 0.7 0.2 0.3 0.0 0.2 0.4 0.6 0.0 118.0 0.2 0.1 0.0 108.1 0.7 0.0 0.0 0.3 0.0 0.4 0.5 266.4 2.4 3.3 0.3 0.1 161.1 65.0 0.5 0.2 0.2 4.6 0.4 0.3 0.1 0.1 1.2 1.8 0.1 0.4 0.5 0.2 0.3 87.0 1.3 0.0 0.8 0.8 0.4 93.7 91.2 123.4 0.1 94.5 0.4 226.1 480.0 521.4 634.4 885.8 541.8 249.0 437.0 618.1 385.8 245.8 489.8 494.1 844.3 506.9 1015.8 57.4 508.6 1340.6 3.8 3.3 4.4 4.3 3.5 5.6 12.9 8.6 11.5 7.9 6.9 14.7 12.6 44.8 62.3 0.7 525.2 15.8 0.9 0.0 4.0 0.3 6.0 9.3 4.6 5.7 14.2 1.8 0.0 0.6 1026.4 1.0 0.0 0.7 2.4 2.3 2.3 15.1 1.2 58.8 0.7 0.0 0.9 17.2 46.9 2.7 246.5 0.1 14.6 6.9 96.0 0.0 1.7 0.4 0.0 334.9 214.5 3.5 1.2 534.1 21.4 201.4 554.9 0.1 769.3 2.5 0.7 0.1 0.8 0.0 474.2 1.1 0.1 2.5 11.7 0.2 6.6 7.4 6.7 0.3 0.6 1.8 15.2 0.8 1049.1 5.4 0.9 0.8 PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10612723 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.8" "Group enriched" "Detected in many" 12 "Excitatory neurons: 4579.7;Inhibitory neurons: 1152.9;Oligodendrocyte precursor cells: 1170.2;Oligodendrocytes: 3151.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 21.1;HAP1: 4.3;HSkMC: 6.3;RH-30: 8.1;SCLC-21H: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 20000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" 2.1 0.6 10.8 0.3 24.7 0.1 0.9 12.2 26.2 5.6 0.0 3.3 1.8 2.4 0.2 0.6 2.2 1.0 2.5 14.4 7.2 6.6 3.6 4.6 0.0 14.6 10.1 12.1 1.3 18.7 4.3 5.3 19.1 1.9 2.5 6.4 0.5 0.6 0.9 0.7 5.0 1.0 10.4 0.4 0.9 1.6 17.6 0.7 3.4 0.8 0.0 2.2 3.4 70.8 0.0 0.1 21.1 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.7 3.6 0.5 0.0 0.0 0.0 0.1 6.3 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.6 0.0 3.4 0.0 3.2 2.3 8.1 0.0 1.8 0.0 4.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 24.7 12.2 26.2 14.4 7.2 14.6 10.1 19.1 10.4 17.6 70.8 0.5 0.0 3.2 199.2 0.1 0.5 0.4 3.2 6.2 134.2 0.3 0.1 6.5 27.1 1.8 5.5 16.7 0.3 0.0 16.4 0.0 3.6 15.8 0.8 15.0 1.2 35.4 0.0 4579.7 0.0 0.3 15.5 0.5 1.0 0.0 9.2 1.4 13.5 1.3 5.0 1152.9 13.2 0.0 0.8 0.0 6.5 15.8 1.6 0.0 85.3 0.1 36.1 0.0 1170.2 3151.1 0.2 9.2 0.0 2.7 2.1 18.3 26.3 0.2 7.8 0.0 4.0 5.8 2.4 3.2 0.4 0.9 0.3 0.8 6.0 8.7 0.1 PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase receptor type G" P23470 3 61561569-62297609 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 356.8;Excitatory neurons: 416.1;Inhibitory neurons: 684.3;Microglial cells: 771.0;Oligodendrocyte precursor cells: 920.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 81.7;HSkMC: 61.1" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" NA NA 520000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA000546: , HPA064237: AB_2685221" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" 18.0 13.2 7.6 4.6 7.8 0.0 12.8 4.9 10.4 11.9 23.4 8.2 3.7 10.6 8.4 4.1 9.0 8.3 10.0 13.7 6.2 14.4 5.8 12.8 1.8 8.4 7.2 12.0 3.9 26.6 5.2 9.9 5.9 7.8 6.1 8.6 5.2 8.4 7.4 4.5 5.9 13.0 10.0 7.0 5.8 7.7 9.1 2.1 13.1 10.4 1.7 7.0 6.7 5.0 0.0 5.3 27.3 0.0 81.7 41.6 13.5 17.6 28.5 18.2 24.4 13.2 0.5 0.6 10.1 20.7 14.5 0.2 13.4 13.6 28.3 1.5 7.7 1.4 0.1 15.0 27.5 7.5 0.1 61.1 5.3 25.9 30.9 5.8 19.7 2.0 0.0 17.3 16.3 7.6 0.0 0.1 17.0 0.1 0.0 11.9 8.6 0.6 18.2 8.2 2.1 4.5 4.3 0.1 6.9 11.2 0.2 0.3 46.0 25.4 24.1 41.0 14.7 5.5 6.8 0.0 19.2 3.2 31.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.6 7.8 4.9 10.4 13.7 6.2 8.4 7.2 5.9 10.0 9.1 5.0 45.3 12.8 32.4 356.8 2.2 9.2 6.4 5.0 13.1 98.5 9.6 6.3 12.5 8.6 5.8 22.0 6.2 10.5 0.9 12.1 5.9 9.6 3.6 14.4 31.9 55.5 24.6 0.0 416.1 1.8 0.8 47.7 4.1 30.5 0.0 64.6 90.3 32.7 19.7 154.8 684.3 8.9 22.4 2.9 8.8 4.3 66.5 1.1 17.8 771.0 0.6 40.8 2.1 920.3 11.8 5.3 5.6 56.8 4.2 10.9 13.9 18.2 2.8 5.7 72.3 81.1 60.6 2.0 8.6 2.1 4.8 12.6 2.3 20.0 12.1 2.7 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 193.6;Inhibitory neurons: 231.1;Oligodendrocyte precursor cells: 126.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.9;NTERA-2: 5.8;SH-SY5Y: 6.1;THP-1: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 1.8 0.8 8.7 3.0 9.4 0.2 0.8 0.0 10.3 1.3 0.1 10.4 1.7 4.8 1.4 0.4 1.0 1.2 0.5 9.8 8.9 36.3 1.3 6.8 3.1 2.2 3.3 0.4 0.4 0.3 2.4 4.4 5.3 0.5 26.8 7.5 0.5 0.8 0.3 0.4 2.0 6.6 0.9 3.4 0.8 0.5 9.5 1.2 0.3 0.5 3.2 1.5 0.4 2.9 0.0 0.1 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.5 1.3 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.8 1.2 0.0 0.0 0.0 0.0 0.1 0.2 1.5 6.1 0.9 0.0 0.1 0.1 0.1 2.7 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.0 0.1 1.2 0.0 6.0 0.0 0.0 12.3 0.0 8.9 1.7 0.4 8.5 8.6 2.8 1.2 0.1 0.1 12.7 10.9 1.4 3.2 8.7 9.4 0.0 10.3 9.8 8.9 2.2 3.3 5.3 0.9 9.5 2.9 0.2 0.0 0.5 7.5 7.0 0.3 1.3 0.5 0.0 25.2 0.0 0.1 0.7 0.0 1.8 16.5 0.0 0.2 4.0 3.9 0.0 0.4 0.0 0.8 0.2 1.1 3.6 0.0 193.6 0.0 0.2 0.9 0.0 0.6 0.0 0.0 1.1 0.2 26.1 25.2 231.1 8.3 0.0 21.1 10.6 0.6 0.6 10.5 0.0 17.8 13.8 0.6 1.0 126.7 6.3 0.1 9.8 0.4 1.0 0.1 0.1 0.2 0.0 4.8 0.0 2.1 0.7 0.6 1.1 0.1 0.4 0.3 1.0 0.1 22.4 0.8 PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.8;Inhibitory neurons: 104.2;Melanocytes: 80.0;Oligodendrocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "plasmacytoid DC: 12.5" "Lineage enriched" "Detected in single" 89 "dendritic cells: 12.5" "Cell line enhanced" "Detected in many" "AN3-CA: 121.8;HaCaT: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 150000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 54.7 21.2 34.4 5.0 25.5 1.5 36.2 3.2 30.9 40.2 0.0 25.2 2.6 30.5 2.2 16.5 41.1 13.7 37.0 34.3 10.0 11.2 6.0 26.9 5.5 16.4 16.4 35.8 32.4 9.7 29.1 2.3 17.6 30.5 1.6 5.7 18.6 14.6 14.4 20.6 13.6 8.6 1.6 9.0 23.2 9.9 27.3 4.2 29.4 7.4 4.4 32.0 31.8 34.9 11.3 64.0 56.2 121.8 25.3 20.5 7.4 19.4 22.5 22.8 18.5 0.7 6.2 0.2 44.5 32.2 18.0 124.6 15.1 0.2 10.0 1.5 24.3 0.0 27.2 40.5 11.7 0.0 14.1 21.8 5.4 4.8 0.9 29.4 0.6 7.9 18.5 0.2 9.1 48.0 5.2 12.3 31.7 0.4 27.0 0.0 12.4 0.0 4.7 22.5 43.1 58.9 18.3 3.4 34.6 10.7 22.0 4.8 2.8 20.2 34.3 46.9 23.6 6.2 0.1 36.9 10.5 0.0 44.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 34.4 25.5 3.2 30.9 34.3 10.0 16.4 16.4 17.6 1.6 27.3 34.9 1.1 6.4 1.1 53.8 3.2 60.9 42.4 16.1 22.2 49.6 3.3 5.5 14.1 27.1 4.9 12.9 2.1 0.7 56.4 0.1 9.8 1.4 3.4 5.4 11.4 9.7 3.0 0.0 76.8 0.9 32.2 51.2 5.1 5.3 0.0 4.0 25.4 20.2 1.7 11.8 104.2 0.0 10.2 0.3 20.0 5.4 46.6 3.4 80.0 15.9 0.8 46.6 0.0 71.9 90.2 0.5 0.0 36.1 6.3 35.0 0.0 2.9 1.7 10.1 13.1 46.4 22.6 7.4 14.8 16.8 36.7 1.0 2.0 2.7 0.4 30.0 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 312.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.3;Hepatocytes: 577.4;Proximal enterocytes: 333.3;Proximal tubular cells: 303.7" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 85: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" 24.8 14.7 23.7 7.5 24.3 23.4 18.7 24.5 29.8 14.3 37.7 49.5 52.1 14.9 22.3 16.2 18.7 15.4 62.9 28.5 24.1 58.2 312.0 12.9 11.5 24.1 24.2 23.0 42.5 14.5 9.3 8.1 22.9 19.8 39.2 7.5 18.6 9.7 42.3 16.8 55.1 9.5 23.0 13.1 98.2 9.1 24.9 25.9 14.7 30.5 10.7 15.9 12.8 23.5 60.5 24.8 36.6 34.1 21.5 16.6 21.4 21.0 19.4 44.7 39.6 30.3 22.4 37.2 24.9 30.0 15.7 42.0 49.1 26.6 24.3 21.3 77.8 33.2 43.9 33.8 41.7 24.8 14.4 21.7 21.8 18.6 14.7 31.2 12.1 56.2 58.2 28.4 23.8 54.2 78.9 39.2 35.7 70.0 33.9 80.1 39.2 30.6 32.9 25.2 69.0 22.5 45.6 23.6 29.6 28.1 63.2 56.0 14.3 21.9 51.1 19.1 35.6 25.7 26.7 60.6 24.6 34.9 17.7 0.0 1.2 2.9 2.3 0.6 2.1 2.5 1.8 2.4 2.1 2.7 1.8 1.5 0.7 1.5 0.6 6.3 3.1 1.2 23.7 24.3 24.5 29.8 28.5 24.1 24.1 24.2 22.9 23.0 24.9 23.5 10.9 3.2 7.2 8.1 8.2 8.4 20.0 10.6 15.4 6.1 50.3 51.1 35.8 138.7 6.0 25.8 4.2 60.1 7.3 187.3 166.3 16.5 18.7 11.8 16.9 14.1 18.7 55.9 5.9 10.3 36.6 17.0 65.7 17.4 4.5 32.4 46.8 577.4 34.9 0.0 7.1 85.1 2.0 19.2 9.4 38.8 31.1 8.1 12.4 5.6 2.7 45.5 13.4 4.5 1.0 10.2 143.4 35.0 20.9 28.1 333.3 303.7 2.1 7.3 19.7 7.5 14.8 44.9 30.2 31.2 10.7 28.5 8.1 12.4 158.6 23.2 PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.8;Distal enterocytes: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 407.8;SK-MEL-30: 528.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 14000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031067: AB_2673722" "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.37e-4)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.43e-4)" 50.8 36.4 78.2 27.7 77.9 14.1 61.1 84.1 82.4 37.0 35.4 140.9 27.0 51.9 21.4 106.6 37.8 39.1 163.9 77.3 74.9 43.7 14.6 32.1 19.1 85.4 80.8 25.9 25.4 18.1 61.5 11.5 81.2 107.9 72.6 25.4 125.1 106.3 18.7 85.3 44.8 59.8 84.7 22.6 51.3 25.2 80.3 18.4 45.2 10.5 17.3 154.2 53.0 84.8 31.5 220.1 39.1 38.3 97.9 182.7 28.7 62.2 80.9 51.4 43.0 50.1 38.0 37.1 71.8 83.6 96.1 123.9 44.5 165.8 27.9 21.1 27.5 29.5 18.6 86.9 115.7 44.7 40.0 107.1 152.4 130.5 191.3 63.5 66.6 23.0 16.5 91.4 73.0 87.1 45.1 34.6 35.2 38.2 407.8 33.7 71.0 49.8 280.5 56.8 58.4 36.5 42.7 74.0 528.7 31.0 51.9 28.4 147.4 60.3 36.5 65.1 128.7 35.2 58.8 14.4 67.9 34.8 335.3 4.6 14.1 7.1 10.2 19.4 9.9 5.4 8.1 9.2 14.5 4.6 10.3 12.9 3.3 11.2 23.4 7.1 9.6 23.4 78.2 77.9 84.1 82.4 77.3 74.9 85.4 80.8 81.2 84.7 80.3 84.8 10.0 9.6 34.6 43.1 8.7 11.9 23.1 20.7 22.2 35.8 31.6 43.6 122.8 11.5 14.6 25.8 37.5 7.1 10.7 185.2 11.7 17.6 3.5 12.7 17.2 13.5 28.2 8.6 22.9 16.5 7.2 15.3 40.2 21.6 6.3 16.2 8.9 5.8 10.8 18.5 26.9 47.3 57.0 13.8 10.7 9.2 27.4 18.5 35.6 15.0 16.6 21.3 15.5 11.6 19.1 27.0 68.5 86.5 22.9 17.6 20.9 11.1 11.9 9.3 0.0 13.5 23.1 2.0 8.5 15.3 10.1 4.4 12.9 20.3 72.0 9.7 PYGL GSD6 ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944483 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 145.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 151.2;Hofbauer cells: 177.6;Muller glia cells: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 141.1;neutrophil: 153.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 279.1;HMC-1: 304.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Supported "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane, Cytosol" "HPA000962: AB_1079722, HPA004119: AB_1079723" "unprognostic (2.70e-2)" "unprognostic (8.64e-3)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (9.41e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.95e-2)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-3)" 110.1 21.0 5.9 24.1 6.6 108.9 36.4 5.0 8.4 33.6 10.4 19.0 3.7 20.7 6.4 55.8 19.1 13.0 14.9 5.2 6.2 10.2 145.6 26.1 6.3 10.7 17.6 18.2 5.7 21.1 7.5 49.3 8.7 13.0 24.0 78.2 26.8 29.7 5.1 37.0 8.4 26.7 8.6 49.4 9.6 5.2 9.0 4.8 10.2 5.8 6.8 41.7 38.1 10.3 145.7 40.8 10.1 64.3 47.0 56.2 114.5 28.6 24.1 77.4 117.3 107.4 18.3 0.1 54.4 171.7 91.2 279.1 107.0 144.8 132.0 0.5 46.8 28.0 60.5 82.4 83.8 106.9 304.4 119.4 56.8 104.1 43.6 75.4 69.3 0.8 11.6 0.5 55.4 144.7 0.4 141.7 39.3 12.8 152.0 2.7 36.2 6.1 104.7 95.1 4.5 4.4 131.0 43.3 1.7 38.6 20.6 200.4 3.2 29.7 49.6 56.0 92.9 1.2 0.3 0.5 27.3 107.7 15.9 50.2 55.9 141.1 0.0 24.2 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 153.7 0.6 15.7 1.2 0.2 24.8 5.9 6.6 5.0 8.4 5.2 6.2 10.7 17.6 8.7 8.6 9.0 10.3 6.7 22.4 6.3 1.3 1.8 30.7 10.5 40.5 6.8 4.6 7.0 3.8 3.4 5.7 35.4 7.3 0.0 28.9 0.2 11.2 3.9 10.9 1.0 35.4 18.9 7.8 1.2 9.0 1.8 2.1 151.2 18.8 6.6 62.6 6.3 9.3 8.2 65.4 177.6 1.7 2.2 7.1 14.2 56.7 7.9 1.5 14.3 54.6 19.6 15.9 52.4 265.1 2.1 14.1 0.6 7.4 5.2 21.8 1.8 9.7 0.0 6.4 24.5 11.9 6.6 15.4 8.8 0.7 1.4 22.4 22.3 21.1 2.3 4.0 14.0 9.2 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;testis: 48.8" "Cell type enhanced" "Detected in many" "Early spermatids: 334.6;Horizontal cells: 212.0;Late spermatids: 1251.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.7" "Cell line enhanced" "Detected in many" "BEWO: 64.3;Daudi: 36.8;Hep G2: 40.6;HMC-1: 41.5;RT4: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA063203: AB_2684962" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "prognostic favorable (2.70e-4)" "unprognostic (6.03e-3)" "unprognostic (4.29e-2)" "unprognostic (4.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.74e-8)" "prognostic favorable (1.22e-4)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" 0.9 1.1 68.9 8.1 72.0 15.0 4.1 48.9 71.4 2.7 22.0 9.3 12.9 1.2 11.2 6.7 7.5 3.2 2.7 66.2 47.6 6.8 2.9 5.7 11.8 55.3 66.0 2.4 17.6 6.1 3.5 10.5 51.7 2.5 7.3 7.7 7.4 3.8 0.5 8.1 14.7 0.9 54.3 7.4 13.4 48.8 70.7 4.6 4.6 0.4 10.7 5.1 2.1 78.4 12.4 1.4 1.3 3.2 0.5 0.0 64.3 0.2 0.0 0.8 0.8 20.7 1.9 36.8 4.6 0.2 13.3 10.3 12.2 5.9 0.5 7.5 11.0 0.0 0.5 40.6 0.3 2.7 41.5 0.3 5.9 0.8 2.6 0.4 0.0 10.9 2.7 0.9 0.0 9.8 2.7 0.7 10.5 22.9 0.4 1.0 0.1 7.1 2.3 37.8 19.1 13.9 2.8 17.4 14.6 8.7 25.7 1.2 0.0 0.7 6.3 0.1 0.6 6.6 5.6 3.4 0.2 3.7 2.5 5.5 8.4 78.7 13.9 11.9 8.7 5.8 7.2 10.3 5.4 8.6 7.6 9.1 40.5 6.4 15.8 1.1 9.6 8.7 68.9 72.0 48.9 71.4 66.2 47.6 55.3 66.0 51.7 54.3 70.7 78.4 0.6 6.4 8.3 15.7 12.1 3.1 11.4 5.7 1.8 9.6 9.1 5.2 7.3 15.7 9.6 11.0 10.4 73.1 19.8 32.6 13.7 17.5 334.6 39.0 3.9 1.5 14.9 2.7 68.6 28.2 10.9 2.3 17.3 48.8 12.0 7.3 1.1 4.4 6.0 212.0 71.0 16.0 12.2 1.9 5.7 1251.4 5.3 6.3 10.6 1.9 11.1 53.7 26.8 13.6 72.3 24.8 20.2 4.9 7.0 11.1 25.9 12.4 18.1 7.4 0.0 3.1 2.7 8.3 9.7 4.4 3.0 50.3 15.2 0.2 21.1 15.4 RAB17 ENSG00000124839 "RAB17, member RAS oncogene family" Q9H0T7 2 237574322-237601614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.7;liver: 107.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Distal tubular cells: 137.0;Hepatocytes: 121.7;Proximal enterocytes: 222.5;Proximal tubular cells: 170.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.4;Hep G2: 39.9;MCF7: 52.0;SK-BR-3: 48.1;SK-MEL-30: 86.7;T-47d: 34.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA035176 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035176: AB_10696368" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (1.44e-3)" "unprognostic (9.14e-2)" "unprognostic (2.48e-3)" "unprognostic (1.26e-3)" "unprognostic (1.33e-1)" "unprognostic (5.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.68e-2)" "prognostic favorable (4.14e-4)" "unprognostic (5.87e-2)" "prognostic favorable (3.33e-13)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (3.44e-1)" "prognostic favorable (2.51e-4)" 0.8 1.0 0.9 1.6 0.6 0.4 15.0 0.6 1.3 6.7 25.8 16.4 76.7 2.3 19.4 2.1 11.1 14.7 1.5 2.2 0.7 49.8 107.6 23.1 0.4 0.8 0.7 0.6 38.7 36.9 3.0 13.8 0.7 7.0 15.6 4.2 34.8 15.3 1.4 0.9 73.7 1.0 0.6 0.5 33.5 0.7 0.9 1.0 33.4 0.0 0.8 3.8 0.3 0.7 9.5 0.3 0.0 17.7 0.1 0.2 42.4 0.2 0.1 0.0 0.1 28.7 26.6 0.0 5.6 0.2 0.1 0.4 0.0 12.5 0.2 0.0 0.0 0.0 0.1 39.9 0.0 0.2 0.0 0.0 7.8 0.0 0.9 0.7 0.0 0.1 0.0 0.0 1.0 52.0 0.0 0.6 0.5 28.6 0.1 1.1 0.0 3.4 13.7 25.1 10.5 0.1 0.0 48.1 86.7 9.4 34.8 0.7 0.0 0.2 0.6 0.1 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.6 1.3 2.2 0.7 0.8 0.7 0.7 0.6 0.9 0.7 1.2 60.9 34.3 0.3 0.5 1.8 3.4 3.3 22.8 1.7 32.2 18.3 1.0 65.8 11.9 46.0 106.3 16.0 0.1 49.6 137.0 40.0 0.0 18.2 1.6 1.8 30.3 0.0 0.8 28.0 3.8 0.7 29.0 22.1 0.0 0.4 2.5 121.7 1.9 0.0 1.5 23.9 24.4 2.2 0.6 0.7 8.7 1.3 5.4 0.0 0.6 0.2 0.0 1.0 0.1 27.9 50.1 3.8 0.1 5.3 222.5 170.2 13.7 0.6 0.0 0.3 0.7 0.0 0.2 6.6 0.6 12.3 1.3 0.7 21.9 6.5 RAB2A RAB2 ENSG00000104388 "RAB2A, member RAS oncogene family" P61019 8 60516936-60623644 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018781 Approved NA NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "CAB018781: AB_654960" "prognostic unfavorable (8.22e-4)" "unprognostic (1.84e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.25e-1)" "unprognostic (6.69e-2)" "unprognostic (1.37e-1)" "unprognostic (3.39e-2)" "unprognostic (1.96e-1)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (5.10e-1)" "unprognostic (7.57e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-1)" "unprognostic (6.24e-2)" "unprognostic (2.09e-1)" 67.0 52.0 42.6 36.5 49.0 48.7 49.1 38.4 63.0 48.5 30.2 54.4 49.1 45.5 48.9 83.2 32.1 37.7 70.2 48.5 52.3 63.3 70.3 40.9 26.4 41.4 41.7 35.0 43.2 68.6 39.0 51.2 44.4 55.0 48.3 41.2 54.5 37.7 115.8 42.1 53.0 40.0 42.2 33.5 60.6 27.4 44.9 31.2 62.4 69.1 27.8 48.4 59.9 42.2 121.6 68.6 46.2 40.4 152.8 105.9 65.7 101.5 72.5 50.3 58.5 29.5 92.0 39.0 40.2 129.4 83.7 70.8 55.4 64.9 69.2 59.8 45.9 56.3 30.1 40.8 112.9 17.3 48.8 113.9 86.6 57.0 68.6 101.1 62.9 32.6 36.0 51.0 80.1 40.4 75.1 29.3 42.6 176.5 30.6 45.6 20.2 33.9 94.2 55.0 31.6 63.2 43.8 84.2 92.0 60.3 84.1 40.3 104.2 66.9 64.3 100.4 63.0 64.7 49.4 43.6 97.3 37.7 82.7 230.0 164.4 241.2 88.0 149.3 81.5 112.3 90.0 101.2 147.7 108.9 92.2 100.1 310.9 130.2 152.0 97.1 117.7 129.3 42.6 49.0 38.4 63.0 48.5 52.3 41.4 41.7 44.4 42.2 44.9 42.2 167.5 157.0 129.0 67.3 99.3 214.4 197.0 267.0 135.5 102.2 152.6 148.2 182.0 117.2 190.7 165.5 16.7 214.4 112.2 198.6 426.5 266.4 404.2 133.2 200.4 163.8 178.6 56.0 103.7 278.1 365.2 194.9 107.6 197.1 92.5 103.6 121.3 261.9 204.2 124.5 89.6 332.0 266.5 100.2 146.1 111.6 175.2 129.4 279.3 89.0 159.3 153.6 129.8 133.7 124.9 324.4 168.6 165.5 143.8 315.2 200.2 366.4 142.1 60.8 170.9 149.3 236.2 219.7 106.2 210.6 241.5 467.8 102.8 162.7 169.9 335.6 RAB37 ENSG00000172794 "RAB37, member RAS oncogene family" Q96AX2 17 74670578-74747335 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.5;brain: 20.8;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "dendritic cells: 33.4;Excitatory neurons: 33.2;granulocytes: 50.7;Inhibitory neurons: 29.6;NK-cells: 87.6;T-cells: 31.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 269.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.7" "Cell line enhanced" "Detected in some" "HEL: 50.6;HMC-1: 58.7;OE19: 25.4;U-266/70: 84.9;U-937: 34.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (2.10e-2)" "unprognostic (7.04e-4)" "unprognostic (5.95e-2)" "unprognostic (9.80e-4)" "unprognostic (3.49e-1)" "unprognostic (7.04e-5)" "unprognostic (1.74e-1)" "unprognostic (1.48e-2)" "unprognostic (7.62e-3)" "unprognostic (9.47e-3)" "unprognostic (3.05e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (8.80e-6)" "unprognostic (7.30e-2)" "prognostic unfavorable (9.27e-4)" "unprognostic (7.80e-2)" "unprognostic (4.01e-2)" 1.4 1.9 1.5 10.5 2.7 24.5 1.0 20.8 10.5 1.8 0.0 5.4 5.2 1.3 1.8 1.9 1.6 4.8 1.3 1.2 2.8 1.0 12.2 6.8 19.2 11.8 4.6 0.5 0.7 1.7 0.6 1.8 11.3 3.9 5.1 3.3 2.3 0.9 0.6 0.8 8.3 1.9 0.6 17.0 6.7 0.8 11.1 21.3 0.6 2.7 14.9 4.2 1.9 3.7 0.0 7.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 50.6 0.2 0.3 0.1 3.9 58.7 0.5 0.0 0.0 0.0 0.0 0.0 7.3 0.0 18.3 0.0 0.2 15.3 13.0 0.0 25.4 0.0 2.8 0.0 0.0 0.1 0.0 0.8 0.0 0.0 3.6 0.0 2.9 0.2 11.4 0.0 0.0 0.3 0.0 0.0 84.9 3.6 1.1 0.1 34.3 0.0 269.7 13.6 201.5 51.1 28.9 12.9 12.3 22.4 37.8 7.3 12.2 12.5 28.3 63.2 54.0 50.3 1.4 42.8 48.9 1.5 2.7 20.8 10.5 1.2 2.8 11.8 4.6 11.3 0.6 11.1 3.7 0.9 3.2 3.2 1.6 23.1 0.1 0.2 0.3 0.0 7.6 0.8 0.4 1.8 5.7 1.8 0.0 6.2 0.1 33.4 1.3 0.0 1.3 0.0 0.1 0.1 0.9 5.4 16.0 33.2 0.9 0.1 2.0 8.2 0.5 50.7 0.0 2.2 12.6 0.6 3.3 29.6 7.7 14.2 2.2 0.0 0.4 0.6 18.5 0.0 1.9 11.8 1.3 87.6 2.0 1.6 0.4 2.8 1.2 6.3 0.1 0.2 1.5 2.3 1.0 6.6 3.0 1.1 0.0 1.5 0.3 0.1 0.0 31.0 0.5 0.5 0.3 RAB3C ENSG00000152932 "RAB3C, member RAS oncogene family" Q96E17 5 58582221-58859394 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 62.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 140.6;Inhibitory neurons: 509.9;Oligodendrocyte precursor cells: 131.2" "Cancer enhanced" "Detected in some" "glioma: 1.0;pancreatic cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.7;HEL: 2.5;NB-4: 1.6;SCLC-21H: 10.2;SH-SY5Y: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, HPA048156" Enhanced Approved Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA003160: AB_1079731, HPA048156: AB_2680291" "unprognostic (1.30e-1)" "unprognostic (3.35e-2)" "unprognostic (9.94e-2)" "unprognostic (2.23e-2)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (8.73e-3)" "unprognostic (3.40e-2)" "unprognostic (6.90e-2)" "unprognostic (7.58e-2)" "unprognostic (9.52e-4)" "unprognostic (1.51e-3)" "unprognostic (3.70e-5)" "unprognostic (4.70e-2)" "unprognostic (1.05e-1)" "unprognostic (9.65e-2)" "unprognostic (3.61e-3)" 1.1 9.0 19.1 1.2 20.6 0.0 0.7 0.9 32.7 0.1 0.0 0.6 1.6 0.7 0.0 0.2 0.2 0.7 0.1 10.2 62.5 0.0 0.1 0.1 0.2 7.4 12.3 0.3 1.7 0.1 6.8 0.1 31.6 0.0 0.8 6.0 0.1 0.0 0.1 0.0 1.8 0.7 3.9 0.0 0.9 0.1 19.2 0.1 0.1 0.0 0.2 0.6 0.2 3.8 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.2 3.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 20.6 0.9 32.7 10.2 62.5 7.4 12.3 31.6 3.9 19.2 3.8 8.6 0.0 0.6 10.1 0.4 0.1 0.0 0.0 0.0 28.3 0.3 0.3 0.7 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.9 0.1 20.0 0.0 0.1 12.1 57.6 1.3 140.6 9.6 0.8 0.2 0.0 0.0 2.5 0.0 5.7 1.2 0.1 3.3 509.9 5.5 0.0 0.9 1.1 11.8 0.9 0.1 1.8 6.5 0.0 1.6 0.0 131.2 8.4 3.9 1.2 0.7 0.0 0.0 0.3 0.1 0.0 6.7 13.1 0.5 0.2 2.4 4.1 0.0 0.1 0.0 1.3 0.1 0.3 0.0 RAB44 "dJ431A14.3, RASD3, RASL13" ENSG00000255587 "RAB44, member RAS oncogene family" Q7Z6P3 6 36697826-36733184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "bone marrow: 58.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 4.4;granulocytes: 14.5;monocytes: 2.3;Squamous epithelial cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "basophil: 10.6;eosinophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.6" "Cell line enhanced" "Detected in some" "HEL: 21.9;HL-60: 30.9;HMC-1: 88.9;NB-4: 76.7;THP-1: 30.1;U-937: 60.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA079390 Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Vesicles "HPA079390: " "unprognostic (8.86e-2)" "unprognostic (5.58e-3)" "unprognostic (5.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.37e-1)" "unprognostic (1.28e-3)" "unprognostic (9.56e-2)" "unprognostic (6.35e-4)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" "unprognostic (2.57e-1)" "unprognostic (3.02e-2)" "unprognostic (3.13e-3)" "unprognostic (3.03e-2)" "unprognostic (9.67e-3)" "unprognostic (5.79e-2)" 0.5 0.0 0.0 0.6 0.1 58.9 0.4 0.0 0.1 0.4 0.0 0.4 0.6 0.3 0.2 0.5 0.5 0.8 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.4 0.0 0.5 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 30.9 88.9 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 76.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.7 0.0 10.6 0.8 7.2 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 4.4 0.7 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.3 0.0 1.3 0.3 0.2 0.0 0.3 0.0 0.5 14.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.3 0.0 1.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.3 0.0 0.0 2.2 0.0 0.0 0.4 0.1 0.0 0.1 RAB6C WTH3 ENSG00000222014 "RAB6C, member RAS oncogene family" Q9H0N0 2 129979666-129982738 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;breast: 2.5;parathyroid gland: 3.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 10.3;Oligodendrocytes: 3.3" "Group enriched" "Detected in some" 5 "breast cancer: 0.7;prostate cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.5;HMC-1: 2.2;REH: 5.4;T-47d: 3.2;U-266/70: 2.1" HPA059131 Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 43: Cardiomyocytes - Nuclear processes" "Golgi apparatus" "HPA059131: AB_2683916" "unprognostic (3.84e-2)" "unprognostic (5.77e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (2.54e-1)" "unprognostic (8.62e-2)" "unprognostic (1.83e-1)" "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (1.50e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (4.48e-2)" "unprognostic (6.04e-2)" "unprognostic (1.24e-1)" "unprognostic (4.78e-1)" 0.1 0.6 1.4 0.1 2.2 0.0 2.5 0.7 1.9 1.9 0.7 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 1.3 1.6 0.1 0.0 0.0 0.0 1.2 1.2 0.1 0.0 3.6 0.2 0.3 1.3 1.7 0.0 0.3 0.0 0.4 0.1 0.0 0.1 0.0 0.7 0.5 0.0 0.9 1.6 0.0 0.1 0.0 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.4 0.1 0.5 3.2 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 0.7 1.9 1.3 1.6 1.2 1.2 1.3 0.7 1.6 3.6 0.1 0.0 0.0 0.3 0.1 0.8 0.3 0.3 0.0 0.0 0.9 0.1 10.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.1 1.7 1.0 0.0 0.0 0.7 0.0 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.3 0.4 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.7 0.0 0.6 0.7 0.0 0.1 0.0 0.0 0.6 1.4 1.4 1.3 0.0 1.1 0.5 0.1 0.1 0.1 0.3 RAC2 EN-7 ENSG00000128340 "Rac family small GTPase 2" P15153 22 37225270-37244448 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 411.9;lymphoid tissue: 387.9" "Cell type enhanced" "Detected in many" "B-cells: 329.0;dendritic cells: 381.4;granulocytes: 520.5;NK-cells: 717.9;Plasma cells: 287.8;T-cells: 419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 522.5;HL-60: 734.5;HMC-1: 1427.9;Karpas-707: 684.5;U-87 MG: 618.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022946, HPA047820" Enhanced NA Yes 3300000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022946: , HPA047820: AB_2680167" "prognostic favorable (1.03e-5)" "unprognostic (2.91e-1)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (6.74e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-1)" "unprognostic (5.00e-2)" "unprognostic (8.52e-3)" "unprognostic (2.65e-1)" "unprognostic (7.65e-2)" "unprognostic (3.81e-1)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.45e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.50e-2)" 24.7 8.4 3.6 207.2 3.8 411.9 11.4 3.9 8.0 12.2 4.4 34.8 35.3 10.1 4.7 15.9 11.7 37.1 6.5 3.8 4.7 10.9 19.3 63.4 387.9 6.5 5.3 5.5 5.3 2.1 3.4 12.4 7.1 10.9 33.9 0.4 21.5 8.3 4.9 7.6 96.9 19.6 5.2 299.9 42.7 3.5 6.1 323.9 9.5 7.2 309.1 54.0 9.9 7.2 136.6 0.2 0.0 0.0 14.3 130.5 0.6 17.9 41.1 14.2 28.8 0.3 44.8 167.4 19.8 52.9 0.8 33.3 1.0 231.6 15.6 522.5 0.6 209.6 3.6 0.6 35.8 734.5 1427.9 96.4 32.3 25.1 84.3 0.9 239.7 159.1 50.5 684.5 1.9 0.2 218.9 291.2 2.8 13.1 87.2 72.3 0.7 193.8 22.6 0.1 2.0 0.6 0.9 23.0 2.7 0.8 9.7 391.8 258.7 0.6 23.5 1.0 2.0 307.0 171.4 176.6 618.6 316.5 35.1 1319.9 519.8 1602.2 972.1 695.5 731.5 761.7 768.6 858.9 494.0 672.8 584.3 759.8 1336.4 972.2 879.5 728.7 1163.4 1566.2 3.6 3.8 3.9 8.0 3.8 4.7 6.5 5.3 7.1 5.2 6.1 7.2 4.4 16.0 47.7 0.0 329.0 5.4 2.2 26.0 16.5 0.0 8.6 9.5 1.1 2.8 12.6 1.8 0.0 0.8 381.4 3.4 0.0 13.6 0.2 1.1 0.8 5.6 4.2 109.7 0.4 2.2 1.5 9.2 33.6 1.0 520.5 0.3 13.6 3.4 150.8 0.0 0.1 6.3 0.0 129.9 63.9 0.9 0.3 147.9 30.2 3.7 125.9 0.0 717.9 0.5 0.0 18.2 18.1 0.0 287.8 0.5 0.6 1.5 4.4 0.0 13.1 2.4 4.5 0.0 1.0 5.1 4.0 2.9 419.6 3.7 11.2 3.6 RALB ENSG00000144118 "RAS like proto-oncogene B" P11234 2 120240064-120294710 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Cell division" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 335.7" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 378.4" "Group enriched" "Detected in all" 4 "granulocytes: 378.4;monocytes: 176.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026010, HPA065232" Enhanced NA NA 440000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026010: , HPA065232: AB_2685440" "unprognostic (5.16e-2)" "unprognostic (9.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.38e-2)" "unprognostic (3.89e-2)" "unprognostic (5.92e-3)" "unprognostic (1.77e-2)" "unprognostic (4.15e-2)" "unprognostic (4.91e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (2.29e-2)" "unprognostic (8.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" 53.8 35.9 30.6 57.2 30.8 60.0 39.9 32.8 38.7 44.3 33.1 59.2 50.5 37.5 15.8 73.3 45.7 44.8 51.0 32.3 37.7 56.5 34.2 50.7 35.8 30.8 33.6 28.7 25.6 335.7 16.6 63.1 30.6 51.0 51.8 25.8 36.2 31.7 30.1 25.7 44.8 46.5 31.3 54.2 39.3 29.9 37.9 27.5 30.8 43.9 35.0 51.0 49.1 32.8 179.8 47.7 46.8 29.5 71.2 115.5 66.7 121.4 105.8 93.3 70.5 99.4 118.0 7.1 63.9 131.6 88.2 64.1 22.5 93.1 85.7 293.3 25.8 84.4 36.3 71.3 46.0 45.1 144.9 60.3 99.0 97.2 74.0 77.1 272.9 6.3 66.5 28.1 108.2 91.9 5.9 100.0 31.7 71.6 101.9 1.2 59.3 38.1 97.5 45.6 13.3 32.1 50.4 137.9 85.1 39.3 43.3 66.3 168.4 91.1 69.8 93.9 48.8 16.2 9.1 12.8 72.7 57.5 95.6 101.8 80.9 230.5 19.0 117.7 18.5 45.0 18.0 19.0 65.4 59.6 11.9 13.7 378.4 25.5 176.1 6.9 24.6 59.5 30.6 30.8 32.8 38.7 32.3 37.7 30.8 33.6 30.6 31.3 37.9 32.8 69.3 9.6 27.0 6.5 23.8 19.4 30.1 22.4 7.4 4.1 23.2 7.9 55.8 18.6 21.9 11.0 12.5 6.0 11.8 95.3 66.5 84.9 18.8 28.4 22.8 77.8 18.6 8.4 12.9 55.0 128.5 32.7 17.9 26.7 106.1 90.6 78.5 9.8 53.6 13.5 9.7 19.1 18.3 54.3 59.4 23.0 19.9 66.7 35.6 16.9 62.6 26.3 21.6 10.1 5.4 138.1 62.1 31.2 6.7 28.5 44.6 104.4 46.3 7.5 19.7 18.3 33.4 13.1 16.2 16.4 18.9 36.7 19.5 12.9 31.3 32.2 RAMAC "C15orf18, FAM103A1, HsT19360, MGC2560, RAM, RAMMET" ENSG00000169612 "RNA guanine-7 methyltransferase activating subunit" Q9BTL3 15 82986210-82991057 "Predicted intracellular proteins" "mRNA capping, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 108.2;Extravillous trophoblasts: 82.2;Hofbauer cells: 69.4;Syncytiotrophoblasts: 92.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041923, HPA041948" Supported Supported Nucleoplasm No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041923: AB_10796467, HPA041948: AB_10797270" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" "unprognostic (5.30e-2)" "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (3.63e-3)" "unprognostic (2.09e-2)" "unprognostic (4.72e-2)" "unprognostic (7.46e-3)" "unprognostic (9.57e-2)" "unprognostic (2.72e-2)" "unprognostic (9.47e-2)" "unprognostic (2.45e-1)" 12.9 14.8 10.9 16.4 11.4 30.1 26.1 12.9 14.8 16.6 11.6 18.4 14.5 18.2 30.1 24.1 19.5 13.4 14.8 11.6 12.2 16.8 24.2 13.0 23.0 11.6 11.3 20.6 16.4 18.8 12.9 25.9 11.3 18.0 19.3 19.9 18.2 15.2 29.1 21.5 13.4 16.8 11.6 14.1 19.0 15.6 11.1 23.3 18.2 20.2 28.9 20.8 15.6 11.6 34.1 44.7 44.3 27.1 23.5 15.9 32.7 33.7 33.5 37.6 30.4 49.4 42.9 16.8 45.8 29.2 45.4 37.9 77.1 32.4 40.6 42.0 49.7 52.7 22.7 58.7 33.3 38.0 44.9 34.9 61.4 30.6 38.5 28.7 23.6 28.5 62.8 33.9 39.8 35.7 29.5 48.3 52.0 45.0 21.1 33.4 38.2 26.0 49.0 64.6 41.1 42.0 34.6 36.7 87.0 71.5 58.6 47.9 16.8 27.5 34.9 26.1 48.8 53.1 104.0 41.8 25.2 50.7 34.5 138.6 59.2 98.2 47.9 57.0 51.8 64.8 54.1 52.3 56.1 61.1 53.9 53.4 117.4 70.4 62.8 51.6 69.9 65.9 10.9 11.4 12.9 14.8 11.6 12.2 11.6 11.3 11.3 11.6 11.1 11.6 18.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 19.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 82.2 10.0 0.0 0.0 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 92.9 2.7 0.0 0.0 0.0 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1717.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes 75000 "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 27.5 72.9 78.2 26.0 86.0 48.1 29.6 70.8 102.3 34.4 47.7 29.2 18.1 24.9 12.0 79.8 23.6 17.2 45.1 79.5 85.2 43.9 88.0 41.6 30.6 102.7 77.9 32.5 60.9 12.7 57.4 22.8 105.1 39.3 13.2 32.7 38.0 17.6 43.0 96.9 30.6 17.5 68.7 42.3 39.6 178.1 82.0 40.4 34.4 14.2 31.8 34.7 45.4 109.1 228.0 112.2 75.9 77.3 38.8 31.4 85.9 194.5 103.8 182.8 98.4 135.9 71.9 118.0 154.0 137.4 94.8 203.0 135.5 145.4 125.2 95.7 199.2 103.3 115.0 107.9 46.7 171.6 72.5 30.0 69.5 132.2 123.4 67.6 102.1 45.0 127.7 83.3 111.9 186.1 96.3 130.0 84.5 217.6 127.6 118.8 73.4 126.0 72.5 123.7 66.6 44.1 139.1 117.7 71.7 74.6 72.2 64.4 146.5 141.7 138.5 78.6 154.6 60.1 92.8 124.2 99.3 119.3 82.0 2.7 7.6 6.9 8.1 9.0 9.5 5.9 8.2 7.8 5.6 6.4 7.4 5.9 2.0 5.9 12.9 5.9 9.5 8.2 78.2 86.0 70.8 102.3 79.5 85.2 102.7 77.9 105.1 68.7 82.0 109.1 10.9 3.2 20.9 8.5 15.0 23.1 22.2 10.9 18.2 16.0 22.4 16.9 19.6 25.8 9.6 9.2 14.6 22.7 20.3 22.9 3.9 33.3 270.7 21.0 14.7 16.1 25.0 16.6 28.3 20.3 35.3 13.3 25.5 25.1 6.3 74.4 8.9 21.8 16.6 15.2 20.8 19.1 16.2 13.9 20.9 1717.0 14.9 16.8 12.4 5.6 8.9 10.1 14.4 6.0 32.2 39.8 5.7 12.0 25.8 37.4 7.1 13.1 11.4 26.4 0.0 6.8 18.2 25.6 17.7 38.8 31.0 23.7 24.3 42.5 24.8 23.3 RAP1B "DKFZp586H0723, K-REV, RAL1B" ENSG00000127314 "RAP1B, member of RAS oncogene family" P61224 12 68610855-68671901 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.20e-1)" "unprognostic (1.47e-3)" "unprognostic (1.11e-1)" "unprognostic (1.20e-1)" "unprognostic (4.15e-2)" "unprognostic (7.23e-2)" "unprognostic (1.60e-3)" "unprognostic (1.48e-1)" "unprognostic (5.83e-2)" "unprognostic (1.80e-1)" "unprognostic (2.01e-2)" "unprognostic (2.86e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.08e-1)" "unprognostic (8.86e-2)" "unprognostic (7.86e-2)" "unprognostic (3.22e-1)" 156.1 107.5 48.2 166.5 53.4 277.9 118.2 55.8 64.2 89.8 62.5 126.4 84.2 120.2 69.7 86.3 78.7 129.7 67.9 49.5 60.0 107.3 141.1 134.9 211.8 58.3 53.5 69.3 78.8 74.1 52.0 133.0 59.7 85.1 111.5 57.6 70.0 135.9 49.5 73.5 121.0 146.4 52.4 153.3 104.4 89.6 55.6 162.5 89.1 57.3 181.1 198.1 83.8 66.2 199.9 133.1 153.2 131.2 317.6 253.1 140.2 414.9 252.1 269.5 203.5 178.9 130.2 280.0 232.8 580.5 124.2 113.4 146.5 202.9 379.8 496.2 125.7 725.2 156.7 120.9 370.8 282.0 407.1 254.8 203.3 289.5 346.0 218.6 298.7 232.1 261.2 445.6 272.0 127.9 265.4 361.7 173.9 86.8 191.3 235.8 181.9 211.1 204.9 488.3 59.6 93.3 209.1 124.8 206.1 174.7 160.3 327.2 330.4 243.0 108.9 275.6 229.9 227.1 452.4 342.3 224.7 191.8 212.3 399.1 215.4 205.7 340.1 407.0 221.2 154.1 206.1 297.6 196.2 140.3 222.2 303.4 149.8 469.5 464.3 99.0 186.2 820.8 48.2 53.4 55.8 64.2 49.5 60.0 58.3 53.5 59.7 52.4 55.6 66.2 210.9 80.1 79.9 41.1 166.2 294.4 72.4 150.9 70.6 14.0 73.3 61.0 14.7 37.1 108.9 80.9 22.9 35.5 373.9 176.1 109.5 157.9 99.6 78.5 154.3 132.4 189.5 104.7 45.0 130.8 75.2 123.4 52.0 119.6 147.8 60.5 85.3 32.7 78.5 33.7 46.8 93.5 95.6 111.3 437.6 44.6 38.8 273.1 188.5 105.9 257.3 28.6 362.5 45.8 67.8 186.0 215.6 36.5 228.4 61.4 72.3 182.2 104.0 23.3 6.6 40.3 204.8 46.3 50.2 78.9 297.8 154.5 256.9 123.2 92.2 92.4 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.6;Astrocytes: 143.0;Collecting duct cells: 69.9;Endothelial cells: 53.0;Oligodendrocytes: 45.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 26.9;HUVEC TERT2: 12.1;NB-4: 14.3;RPTEC TERT1: 13.3;TIME: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 44.6 2.8 29.2 2.6 35.0 1.4 44.0 30.3 29.2 26.0 12.5 9.9 4.0 16.4 6.9 13.2 24.1 13.2 21.1 31.4 21.3 40.0 1.9 11.9 4.4 33.6 29.6 38.2 4.7 5.8 6.4 8.9 28.0 13.5 2.4 0.9 21.2 11.0 11.4 9.8 8.8 5.1 22.4 16.2 11.5 3.5 28.9 1.6 32.4 9.0 2.1 14.9 21.3 39.7 2.3 0.6 0.7 2.4 0.3 2.3 0.9 1.7 1.5 0.7 0.4 0.3 6.1 0.1 26.9 3.0 1.1 2.4 0.8 4.5 0.3 3.0 0.4 0.2 2.6 0.2 0.2 0.4 0.3 0.9 0.3 1.3 0.8 3.4 12.1 0.6 0.1 2.9 0.5 1.5 0.0 14.3 0.6 1.0 3.7 0.4 0.1 1.0 13.3 2.5 0.2 0.3 0.2 1.7 0.4 0.8 6.7 0.6 12.0 6.6 1.1 1.5 0.6 1.0 0.4 0.2 4.1 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 35.0 30.3 29.2 31.4 21.3 33.6 29.6 28.0 22.4 28.9 39.7 130.6 0.0 11.7 143.0 0.7 2.7 5.8 2.6 13.1 0.5 4.5 4.8 15.7 2.8 3.6 69.9 0.0 0.2 1.4 1.7 7.9 1.1 1.6 11.8 2.4 53.0 0.0 0.0 1.5 0.7 0.4 6.3 18.3 21.2 3.8 1.5 20.7 0.2 0.9 0.0 2.9 6.6 4.1 0.6 2.6 3.7 24.2 1.5 5.4 12.2 0.0 1.5 2.1 10.6 45.7 5.8 6.3 8.6 4.4 11.6 0.8 41.3 1.9 0.5 6.6 2.7 5.1 1.2 1.6 1.4 3.3 0.3 1.3 6.6 0.8 17.2 RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 152.1;parathyroid gland: 387.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 504.6;Inhibitory neurons: 193.4;Microglial cells: 138.7;Oligodendrocytes: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 21.1;HUVEC TERT2: 45.0;SCLC-21H: 34.1;TIME: 25.8;U-698: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" 21.0 12.7 30.7 7.0 82.9 0.9 16.4 76.1 58.5 8.9 2.9 9.5 7.5 8.8 4.8 13.9 8.3 16.8 16.8 45.7 46.9 16.7 21.8 37.5 14.3 115.3 71.8 6.5 20.1 387.8 7.4 67.2 107.1 5.1 11.0 4.2 7.6 5.7 5.1 9.2 8.3 12.1 82.0 50.9 7.0 6.4 59.8 15.7 11.7 11.1 10.7 9.3 11.9 152.1 2.8 0.0 4.6 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 5.5 1.4 21.1 1.1 0.3 0.7 13.0 2.8 1.9 0.0 0.0 4.2 0.3 0.0 5.4 0.1 0.0 0.1 0.5 2.4 1.3 0.7 0.7 45.0 5.9 4.8 0.1 0.0 1.2 3.0 0.1 3.6 5.4 4.0 5.2 0.0 7.4 4.2 1.9 34.1 9.0 0.5 6.0 0.1 0.7 3.0 0.1 25.8 0.0 1.0 0.4 1.1 10.9 2.5 37.4 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 82.9 76.1 58.5 45.7 46.9 115.3 71.8 107.1 82.0 59.8 152.1 125.5 9.6 16.5 13.4 3.1 11.0 4.2 2.4 86.0 30.6 8.8 5.5 10.0 15.7 3.8 0.0 0.0 0.3 0.6 16.0 1.9 6.5 61.5 3.3 1.2 70.1 7.2 0.4 504.6 7.0 0.1 5.3 16.3 10.8 8.2 0.1 86.0 6.3 0.2 23.5 193.4 18.3 2.0 3.1 2.0 65.2 1.8 0.9 7.2 138.7 0.0 0.6 0.0 28.1 640.8 5.0 20.3 4.9 12.9 3.0 18.1 0.3 0.5 1.6 85.5 1.4 21.5 1.2 1.6 19.8 11.2 0.3 2.4 1.9 10.1 4.4 RASA3 "GAP1IP4BP, GAPIII" ENSG00000185989 "RAS p21 protein activator 3" Q14644 13 113977783-114132623 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 55.0;Horizontal cells: 60.6;NK-cells: 48.4;Plasma cells: 40.0;T-cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046759 Uncertain NA NA 1400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA046759: AB_10959887" "unprognostic (3.41e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (2.75e-1)" "unprognostic (6.15e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-3)" "unprognostic (4.01e-2)" "unprognostic (3.92e-1)" "unprognostic (2.02e-1)" "unprognostic (1.15e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.99e-6)" "unprognostic (8.98e-2)" "unprognostic (8.16e-3)" "unprognostic (5.08e-2)" "unprognostic (4.11e-2)" 32.2 3.5 7.6 10.9 8.7 12.7 23.2 6.5 9.8 24.4 3.8 17.0 2.9 13.7 1.1 4.9 19.2 4.6 12.9 8.5 8.3 11.2 5.0 19.3 15.6 9.6 8.9 7.6 10.8 0.7 15.2 5.3 9.3 11.3 2.7 2.6 6.8 3.6 14.2 13.0 15.8 4.7 8.0 22.6 9.4 5.9 10.0 9.0 14.4 4.2 7.7 18.5 15.0 14.6 3.8 4.6 20.2 5.8 19.2 21.3 0.0 14.8 22.1 13.1 10.9 0.4 11.6 0.4 8.2 24.1 10.9 0.0 3.0 7.0 10.1 0.9 1.3 29.4 14.1 0.1 9.7 12.3 2.5 19.2 1.4 12.7 9.1 16.2 22.3 0.6 2.2 3.3 19.9 5.1 27.1 20.5 4.3 3.2 6.8 13.6 7.4 60.6 11.9 0.1 2.9 2.1 3.5 15.2 7.5 8.3 3.8 44.7 30.5 19.7 5.4 7.2 16.2 0.1 0.0 0.8 25.7 11.9 32.1 16.7 4.5 6.4 16.9 7.6 12.8 5.2 15.6 17.0 3.0 3.9 16.3 16.4 2.5 12.7 15.3 1.0 19.2 16.9 7.6 8.7 6.5 9.8 8.5 8.3 9.6 8.9 9.3 8.0 10.0 14.6 5.3 0.0 4.2 27.1 20.6 3.7 1.2 0.7 2.2 7.9 2.0 4.6 7.5 1.5 3.5 1.8 0.0 0.1 55.0 0.3 0.0 1.1 1.5 7.8 13.3 9.3 3.0 5.5 25.6 2.0 0.2 15.2 3.6 5.1 26.0 1.8 3.9 2.4 9.3 60.6 12.2 2.6 2.0 15.1 12.1 0.7 8.7 19.6 10.6 36.5 11.4 1.3 48.4 17.6 27.5 12.5 0.2 3.8 40.0 1.6 0.1 0.4 13.2 3.5 0.0 18.9 11.5 8.6 5.4 0.4 4.8 0.5 45.2 2.5 0.7 1.6 RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.4;dendritic cells: 70.9;granulocytes: 39.3;NK-cells: 139.0;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 30.6;HEL: 25.5;HMC-1: 46.7;Karpas-707: 52.5;NB-4: 27.8;RPMI-8226: 23.5;TIME: 35.5;U-937: 34.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" 3.7 2.6 2.8 17.3 2.9 23.5 1.9 3.1 3.6 1.8 2.9 4.2 4.5 1.5 0.7 2.8 2.2 3.6 1.4 2.9 3.2 3.7 3.6 10.6 32.8 4.2 3.3 0.9 1.4 1.2 1.5 1.0 3.9 2.8 2.3 0.1 3.5 0.9 0.7 1.5 19.8 1.2 4.1 39.4 5.4 0.5 4.2 23.8 3.8 0.4 19.4 4.2 2.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 6.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 30.6 0.0 25.5 0.0 0.0 0.4 20.4 46.7 0.1 0.0 0.0 0.0 0.0 0.2 8.0 0.0 52.5 0.0 0.4 10.9 27.8 0.0 0.0 0.0 3.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 8.7 35.5 0.0 0.0 0.0 0.0 0.4 10.1 15.1 0.0 34.1 0.1 6.4 2.3 12.9 18.4 4.7 10.7 3.1 11.7 20.4 3.4 3.5 9.7 11.8 3.4 12.4 12.8 4.2 9.2 5.5 2.8 2.9 3.1 3.6 2.9 3.2 4.2 3.3 3.9 4.1 4.2 5.2 4.1 3.2 5.6 0.0 39.4 0.3 0.0 0.3 0.0 0.0 2.0 2.2 2.5 2.8 1.4 0.0 0.0 0.2 70.9 0.0 0.0 0.2 0.7 5.4 0.4 5.4 0.0 7.4 0.1 0.6 0.2 1.0 2.6 0.4 39.3 0.0 3.9 4.6 11.3 0.0 0.1 0.0 0.0 11.6 3.5 1.7 0.0 17.2 0.0 13.1 14.2 0.1 139.0 0.5 0.1 0.2 0.0 1.2 23.7 0.2 0.0 1.5 5.7 0.1 0.0 0.5 1.5 0.4 0.6 0.3 0.6 0.4 76.7 1.0 0.2 0.1 RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 220.6;Inhibitory neurons: 407.6;Microglial cells: 89.0;Oligodendrocytes: 395.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cell line enhanced" "Detected in some" "BEWO: 37.8;CACO-2: 23.3;Hep G2: 31.8;HHSteC: 20.8;hTERT-RPE1: 15.3;SuSa: 16.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" 11.2 0.9 10.5 3.4 9.4 1.0 7.3 1.2 14.9 3.4 16.1 2.9 1.8 2.4 0.8 1.3 2.2 5.2 5.4 11.6 4.8 4.8 0.5 3.3 3.5 3.4 2.2 17.6 1.0 2.3 4.1 10.2 2.5 3.6 1.4 22.9 1.5 1.5 2.7 1.1 2.4 2.6 5.1 2.2 1.8 2.0 13.8 1.5 4.7 6.8 2.8 3.4 2.4 10.0 0.0 2.1 0.5 0.3 0.0 0.0 37.8 0.7 9.3 0.4 0.4 23.3 0.0 0.4 11.9 0.0 0.2 0.6 0.0 0.0 1.2 0.6 4.0 0.2 0.3 31.8 20.8 0.0 0.0 1.0 0.1 8.8 0.1 15.3 0.2 0.5 0.0 0.1 0.0 0.3 0.3 0.2 4.5 0.0 0.1 0.2 4.5 0.1 1.4 0.0 0.4 0.5 0.1 0.0 0.3 16.2 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.0 0.0 1.9 0.0 5.2 0.0 2.6 1.5 0.0 0.0 4.2 3.0 0.0 0.0 0.0 0.0 0.7 1.0 10.5 9.4 1.2 14.9 11.6 4.8 3.4 2.2 2.5 5.1 13.8 10.0 45.3 0.0 1.1 10.1 0.6 1.7 0.3 0.1 0.0 15.9 0.2 0.3 5.2 0.0 0.6 9.2 58.4 1.1 2.2 0.2 0.0 0.4 10.2 1.3 0.3 23.7 0.0 0.0 220.6 0.0 26.9 2.5 0.5 1.1 0.0 0.2 5.3 0.1 1.1 1.7 407.6 0.5 0.0 0.3 0.8 3.0 0.9 0.5 1.8 89.0 0.2 3.7 6.2 8.5 395.6 0.7 1.2 9.1 0.9 0.3 1.0 2.1 0.0 42.1 0.0 1.5 0.9 6.7 1.6 0.3 0.6 0.8 7.5 4.1 1.3 0.5 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 20.8;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 18.1;granulocytes: 26.6;Hofbauer cells: 15.1;Kupffer cells: 32.9;Langerhans cells: 11.6;Macrophages: 19.1;monocytes: 25.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 39.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 25.7;HMC-1: 24.0;U-937: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: AB_10961405" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.23e-4)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (4.56e-1)" "unprognostic (2.66e-2)" 3.2 0.8 0.3 6.7 0.3 20.8 0.7 0.3 0.9 1.1 0.4 1.2 1.2 0.5 0.1 1.0 1.0 1.9 0.6 0.2 0.3 0.3 0.7 3.3 1.1 0.9 0.4 0.4 1.1 0.3 0.2 2.3 0.6 0.5 0.8 0.0 0.4 0.5 0.8 0.5 1.8 2.0 0.7 8.9 0.9 0.2 1.1 1.1 0.2 1.4 0.7 2.5 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.7 0.0 0.0 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 12.5 13.5 20.1 0.0 15.4 0.0 0.1 0.3 0.0 9.4 0.1 0.0 0.0 39.4 0.0 17.9 0.7 1.4 4.4 0.3 0.3 0.3 0.9 0.2 0.3 0.9 0.4 0.6 0.7 1.1 1.0 0.2 0.0 0.6 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.3 18.1 0.0 1.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.7 0.0 0.2 0.4 0.0 0.0 26.6 0.0 1.4 0.0 15.1 0.0 0.4 0.0 0.0 32.9 11.6 0.0 0.0 19.1 1.8 0.0 25.7 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.3 1.5 0.0 0.0 0.1 RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 121.8;Endothelial cells: 83.9;Hepatic stellate cells: 94.2;Theca cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 14.7;HeLa: 13.9;HUVEC TERT2: 38.5;SiHa: 21.1;TIME: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA077251: AB_2732337" "unprognostic (9.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-2)" "prognostic favorable (7.17e-5)" "unprognostic (8.44e-2)" "unprognostic (2.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.46e-4)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" 24.4 7.0 5.9 2.6 4.3 0.7 21.0 4.4 4.6 9.2 1.4 5.6 2.5 11.2 1.1 5.1 9.9 3.8 18.8 3.6 4.0 12.6 2.6 27.9 2.2 4.9 5.3 4.9 13.2 1.6 4.1 7.9 5.9 5.5 0.7 0.1 4.8 2.7 7.7 6.0 5.7 4.2 4.5 16.8 10.3 6.8 7.3 1.5 10.5 4.0 1.4 7.6 7.7 3.6 10.2 0.1 0.2 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.6 1.1 0.8 2.2 0.0 0.0 2.5 0.2 2.2 0.0 0.0 14.7 0.2 13.9 0.4 2.2 0.0 0.7 2.2 1.2 0.0 0.0 0.0 38.5 1.3 1.3 0.1 0.0 0.9 0.0 1.3 0.3 0.4 0.0 0.2 0.0 0.4 0.0 0.8 6.7 0.5 21.1 0.0 0.0 0.1 0.1 0.0 52.4 0.0 0.4 0.2 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 4.3 4.4 4.6 3.6 4.0 4.9 5.3 5.9 4.5 7.3 3.6 121.8 0.0 1.3 0.0 1.2 6.5 5.7 2.0 0.6 1.1 5.9 10.8 7.3 1.5 1.2 1.8 0.0 0.4 0.7 0.1 0.0 0.7 5.9 3.2 4.8 83.9 0.0 2.7 3.4 0.7 1.9 9.5 2.0 3.8 0.0 6.0 94.2 1.9 0.7 6.7 1.1 0.1 4.1 6.3 3.0 5.2 10.2 1.0 19.6 16.9 0.0 2.1 0.0 1.5 1.5 0.8 0.0 11.3 1.4 10.1 0.2 0.3 2.1 0.7 19.7 1.9 6.2 1.0 11.0 3.7 6.0 0.3 1.0 40.2 0.2 6.4 RASL10B "RRP17, VTS58635" ENSG00000270885 "RAS like family 10 member B" Q96S79 17 35731639-35743521 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3;skeletal muscle: 31.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 13.8;Early spermatids: 10.4;Late spermatids: 34.6;Muller glia cells: 29.0" "Cancer enhanced" "Detected in many" "testis cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 24.3;HHSteC: 26.7;NTERA-2: 41.3;REH: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046842, HPA057092" Enhanced Approved Vesicles NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA046842: AB_2679835, HPA057092: AB_2683332" "unprognostic (5.78e-2)" "unprognostic (2.15e-2)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (8.60e-2)" "unprognostic (1.24e-1)" "unprognostic (2.69e-2)" "unprognostic (4.98e-2)" "unprognostic (1.97e-2)" "unprognostic (7.13e-2)" "unprognostic (2.61e-2)" "unprognostic (3.18e-2)" "unprognostic (1.71e-6)" "unprognostic (2.41e-3)" "unprognostic (1.00e-1)" "unprognostic (1.32e-2)" "unprognostic (9.60e-3)" 15.4 1.7 25.9 0.1 32.3 0.0 11.3 8.7 25.6 3.9 7.6 1.9 0.7 2.8 0.6 0.4 3.9 0.7 19.3 26.5 18.1 3.0 2.1 1.2 0.1 16.5 19.2 3.7 4.9 5.2 6.7 2.8 18.0 2.9 0.1 9.0 9.1 14.7 31.5 0.8 1.2 0.7 13.2 0.3 1.8 3.0 17.5 0.4 1.7 0.9 0.1 1.4 2.3 12.9 0.0 0.3 6.3 0.0 1.1 0.6 1.8 1.2 0.8 4.3 3.6 8.1 0.0 0.0 0.7 0.2 0.0 0.0 24.3 0.0 1.5 0.0 8.0 0.0 4.1 9.3 26.7 0.0 0.0 19.5 1.5 1.5 0.0 3.4 0.0 13.2 5.5 0.0 0.3 0.5 11.6 0.0 41.3 0.0 0.0 20.8 11.1 18.5 0.0 0.0 18.3 17.8 1.2 0.4 1.7 17.8 2.3 1.2 0.0 2.0 14.5 0.1 0.5 0.0 0.0 5.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 32.3 8.7 25.6 26.5 18.1 16.5 19.2 18.0 13.2 17.5 12.9 0.3 0.0 0.5 0.3 0.0 0.1 0.5 0.0 0.0 3.9 2.7 1.4 13.8 4.3 0.0 1.8 2.1 0.0 0.0 0.0 0.0 1.3 10.4 1.0 0.7 0.7 0.0 0.0 2.6 0.0 0.0 1.9 0.0 1.4 0.0 2.8 0.0 6.7 0.2 6.7 4.9 0.2 0.0 0.6 0.0 34.6 2.1 0.1 0.0 1.0 0.0 29.0 0.0 0.5 0.5 0.3 0.0 3.0 0.0 0.6 0.4 0.1 0.0 1.2 0.0 1.5 2.3 4.8 0.9 0.0 0.0 0.3 0.1 7.0 0.4 0.2 RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 22.5;Peritubular cells: 57.9;Sertoli cells: 98.6;Smooth muscle cells: 55.7" "Cancer enhanced" "Detected in all" "glioma: 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;CACO-2: 14.5;EFO-21: 22.7;NTERA-2: 9.9;SuSa: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (6.13e-3)" "unprognostic (1.06e-1)" "unprognostic (2.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-3)" "unprognostic (1.60e-1)" "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (1.76e-2)" "unprognostic (4.72e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.17e-4)" 27.9 3.9 32.9 5.1 36.8 0.0 15.7 30.8 24.4 49.8 8.5 35.6 3.6 61.6 27.9 19.2 54.7 13.2 53.4 26.0 38.4 6.9 1.1 38.4 3.3 39.4 57.4 16.5 2.4 1.8 7.0 17.0 38.0 52.5 6.7 3.3 8.0 76.4 37.1 12.1 9.4 33.0 38.8 9.6 7.7 15.6 66.1 0.9 8.4 20.6 1.7 40.2 33.5 32.6 0.1 0.1 0.2 0.0 0.6 5.0 0.2 0.0 0.5 0.0 0.0 14.5 0.1 0.0 22.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 17.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 36.8 30.8 24.4 26.0 38.4 39.4 57.4 38.0 38.8 66.1 32.6 7.4 0.0 0.0 22.5 0.0 1.5 3.9 0.0 0.0 0.3 2.0 5.6 16.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4.7 0.3 12.6 3.6 0.0 0.0 0.1 0.0 0.1 15.2 0.5 0.5 0.0 12.3 1.4 0.1 0.3 0.0 0.1 0.0 2.0 0.0 1.3 3.9 13.1 0.2 0.0 2.8 0.0 17.9 0.0 0.0 0.0 0.1 0.0 57.9 0.0 0.4 0.5 0.0 0.0 0.8 98.6 0.9 55.7 0.7 1.1 0.4 0.1 0.3 0.2 0.4 0.2 0.1 RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 77.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.0;monocytes: 258.7;Muller glia cells: 260.3;Proximal tubular cells: 128.0;Skeletal myocytes: 186.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 84.8;intermediate monocyte: 63.9;myeloid DC: 84.2;non-classical monocyte: 37.9" "Group enriched" "Detected in many" 10 "dendritic cells: 84.2;monocytes: 84.8" "Cell line enhanced" "Detected in many" "Karpas-707: 64.3;RH-30: 162.7;RPMI-8226: 54.9;U-937: 85.4;WM-115: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: AB_10795576, HPA077069: " "unprognostic (1.83e-1)" "unprognostic (8.21e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (5.14e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (4.83e-2)" "unprognostic (8.75e-3)" "unprognostic (4.20e-1)" "unprognostic (4.11e-3)" "unprognostic (4.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.42e-1)" "unprognostic (6.20e-2)" 35.3 7.1 57.4 21.7 67.9 8.3 22.7 64.3 58.6 6.5 43.8 18.5 13.6 3.0 8.6 4.7 6.0 10.8 44.8 53.9 58.9 77.3 17.1 11.9 19.7 63.4 64.0 3.6 39.5 5.0 13.0 12.7 65.9 7.9 6.0 26.9 16.7 10.9 14.8 4.8 13.8 8.7 55.8 20.1 9.4 9.0 65.3 10.4 40.7 17.6 9.1 11.4 7.0 69.7 1.4 0.3 6.0 11.4 17.9 1.0 4.1 0.7 1.1 2.0 3.5 5.0 0.6 0.1 2.3 0.8 3.9 0.0 2.6 2.8 2.8 37.8 0.0 0.1 0.2 39.7 19.0 2.6 0.0 13.1 0.0 1.9 0.2 10.9 3.0 1.6 0.0 64.3 2.9 0.0 3.0 43.1 1.2 0.2 1.2 8.1 162.7 54.9 0.4 1.2 1.0 0.8 0.0 0.5 2.0 10.7 1.1 32.4 0.0 0.4 3.6 3.0 6.5 0.7 0.7 0.1 18.9 85.4 54.8 0.0 84.8 0.1 8.7 63.9 0.2 0.0 0.6 3.7 84.2 0.0 0.6 2.6 3.0 6.9 37.9 2.2 0.3 48.9 57.4 67.9 64.3 58.6 53.9 58.9 63.4 64.0 65.9 55.8 65.3 69.7 8.9 19.2 17.2 77.4 3.7 3.7 1.4 3.2 1.2 22.5 9.7 7.0 47.9 37.1 13.1 16.5 4.2 1.2 20.3 10.1 17.6 45.3 1.4 6.4 13.7 9.2 11.5 0.0 17.0 3.8 1.2 28.6 1.5 14.8 1.3 4.2 6.1 20.1 157.0 37.0 33.6 7.4 12.2 84.7 94.3 4.4 10.5 91.0 8.8 35.6 258.7 260.3 54.6 37.7 38.2 4.0 11.3 2.2 4.1 1.0 45.0 128.0 5.9 13.3 26.3 186.4 25.9 0.6 1.9 0.8 1.7 2.6 8.0 4.9 15.0 0.7 RASSF7 "C11orf13, CFAP88, FAP88, HRAS1, HRC1" ENSG00000099849 "Ras association domain family member 7" Q02833 11 560404-564025 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 127.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 224.6;Intestinal goblet cells: 179.2;Paneth cells: 194.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.5;HaCaT: 86.4;SK-BR-3: 75.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA078015 Supported "Centriolar satellite" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite" "HPA078015: AB_2686875" "unprognostic (1.11e-2)" "unprognostic (5.10e-2)" "unprognostic (1.75e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (1.13e-1)" "unprognostic (2.46e-3)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.60e-1)" "unprognostic (2.55e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.99e-1)" "unprognostic (2.83e-1)" "unprognostic (3.58e-3)" 15.6 5.0 7.1 8.5 9.4 6.5 13.8 10.1 10.4 23.4 6.8 50.5 33.6 6.3 15.8 49.2 50.9 10.8 4.9 7.3 7.1 127.5 92.8 44.6 10.7 9.3 6.5 6.6 67.5 6.4 27.4 5.0 9.9 42.6 8.5 1.6 42.5 11.5 1.6 53.5 43.5 1.0 6.4 17.7 63.5 13.2 7.1 8.7 23.3 0.6 5.6 18.6 23.7 6.3 51.7 49.9 2.3 12.8 0.0 0.0 35.2 7.7 5.9 8.0 5.9 52.6 85.5 6.6 34.6 4.2 14.0 86.4 7.3 26.5 1.2 8.9 25.6 4.6 28.0 25.9 5.3 10.8 7.4 0.1 25.5 2.7 2.4 11.0 4.8 13.4 11.7 2.5 0.7 51.7 12.2 23.1 7.1 58.2 28.1 19.2 3.7 14.8 39.2 24.8 10.9 8.4 5.4 75.7 6.6 4.0 34.0 6.9 6.6 1.6 23.5 3.1 15.0 8.6 9.9 5.3 12.8 15.1 6.9 5.2 6.0 23.0 17.7 5.2 16.1 13.6 18.3 15.9 10.5 14.8 14.8 13.2 7.3 8.3 5.7 18.7 21.9 8.9 7.1 9.4 10.1 10.4 7.3 7.1 9.3 6.5 9.9 6.4 7.1 6.3 6.5 86.6 70.0 3.3 19.1 25.4 23.4 118.1 14.2 2.7 39.2 30.6 4.7 92.9 90.4 86.5 0.0 38.9 20.9 224.6 52.8 90.7 17.2 28.8 3.9 8.5 51.0 14.5 5.5 90.5 111.7 5.9 124.4 35.2 15.2 15.5 7.9 73.3 19.9 11.8 2.6 179.2 46.8 11.2 15.7 23.0 2.5 11.5 5.4 1.0 28.7 7.9 21.6 1.5 0.6 148.1 194.4 0.4 12.3 61.8 110.0 44.7 73.4 3.2 0.0 0.3 6.7 4.6 9.7 21.2 25.7 40.5 29.7 4.3 113.1 60.3 RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 125.9;Spermatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 36.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA039890: AB_10794756, HPA052946: AB_2681996" "unprognostic (1.55e-3)" "unprognostic (4.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.28e-2)" "unprognostic (3.60e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.29e-2)" "unprognostic (1.58e-3)" "unprognostic (1.04e-2)" "prognostic favorable (1.71e-5)" "unprognostic (3.91e-3)" "unprognostic (2.42e-2)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" 10.1 8.7 6.8 10.0 6.8 18.2 29.4 9.2 11.3 20.9 41.6 14.5 9.3 20.1 23.4 22.1 28.0 12.7 7.0 7.4 9.2 42.2 14.4 13.5 14.0 6.3 7.3 6.4 18.5 22.1 17.5 8.5 6.4 10.8 12.9 6.2 19.5 23.3 2.3 28.5 12.9 16.4 6.2 7.6 13.1 28.7 8.5 32.4 18.2 3.5 17.3 18.3 18.0 7.3 32.9 24.8 36.0 41.9 18.2 19.4 28.2 44.2 31.1 40.3 56.5 45.7 36.3 95.4 19.9 27.9 38.5 67.3 41.2 89.9 78.5 68.3 33.2 41.8 32.0 44.0 22.2 151.5 43.7 13.9 86.0 61.0 105.3 23.6 16.6 65.7 25.0 69.2 41.6 49.1 112.8 50.6 34.2 60.1 41.5 57.6 65.9 58.9 117.4 34.7 84.1 39.8 74.1 22.4 39.0 20.5 129.1 39.4 12.0 107.2 49.3 52.4 78.0 92.9 108.4 105.3 49.1 72.2 58.8 17.0 6.5 3.9 1.2 24.0 0.5 6.6 1.7 2.1 8.2 5.3 0.9 1.5 2.4 7.9 36.7 8.1 4.7 3.8 6.8 6.8 9.2 11.3 7.4 9.2 6.3 7.3 6.4 6.2 8.5 7.3 13.1 35.3 42.8 10.1 22.9 27.4 44.7 125.9 76.8 4.3 22.6 72.6 10.4 35.8 41.9 29.5 4.2 12.7 25.0 14.5 43.0 30.5 17.7 56.0 19.5 14.2 7.7 37.0 20.3 33.0 9.4 13.2 23.0 67.3 66.1 22.3 5.7 16.4 11.7 1.7 15.5 9.3 16.2 11.4 23.5 14.5 6.5 27.5 23.2 8.4 9.0 2.1 4.1 9.5 2.7 44.9 8.6 5.3 53.8 37.5 17.5 26.1 28.2 7.9 0.0 20.4 14.0 116.6 83.4 36.2 19.7 15.2 13.6 9.8 14.9 45.5 RBM38 "dJ800J21.2, HSRNASEB, RNPC1, seb4B, SEB4D" ENSG00000132819 "RNA binding motif protein 38" Q9H0Z9 20 57391396-57409333 "Predicted intracellular proteins" "Cell cycle, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 136.4;skeletal muscle: 221.7" "Cell type enhanced" "Detected in many" "B-cells: 110.9;dendritic cells: 156.9;Erythroid cells: 280.4" "Cancer enhanced" "Detected in all" "ovarian cancer: 95.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 140.6;U-698: 150.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB017036 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "CAB017036: " "unprognostic (1.03e-1)" "prognostic favorable (3.64e-7)" "unprognostic (3.71e-2)" "unprognostic (7.73e-3)" "unprognostic (4.16e-2)" "unprognostic (4.85e-2)" "unprognostic (1.53e-2)" "unprognostic (4.37e-3)" "unprognostic (3.04e-1)" "unprognostic (9.04e-3)" "unprognostic (3.90e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.13e-2)" "unprognostic (2.29e-1)" "prognostic favorable (1.63e-4)" "unprognostic (1.83e-1)" 11.7 10.7 6.7 26.6 9.4 136.4 12.8 13.3 10.3 18.8 15.1 96.6 8.7 38.4 0.9 16.8 28.9 5.1 72.6 5.9 6.4 16.3 16.4 21.0 43.4 8.6 11.5 27.8 10.8 1.9 12.2 5.5 8.0 27.0 4.1 0.6 19.7 11.9 221.7 9.1 39.8 8.7 6.6 65.8 23.0 38.1 9.4 26.6 9.4 32.7 12.2 42.9 13.6 7.9 20.1 20.4 9.7 25.1 0.0 1.6 56.3 6.5 1.6 13.5 3.5 84.2 20.6 140.6 54.1 1.9 13.2 18.3 8.0 8.0 2.1 29.0 34.5 118.0 7.6 52.6 6.0 57.8 54.2 1.9 3.8 5.7 1.1 1.9 9.2 52.5 100.9 24.6 1.6 87.8 42.7 58.5 36.9 10.7 25.5 82.0 23.6 114.2 10.1 9.2 40.9 26.3 15.2 50.5 24.7 8.7 28.3 79.4 17.0 4.4 42.6 6.0 27.6 60.1 86.8 150.7 1.1 40.3 4.2 0.0 0.5 2.2 3.1 1.8 1.9 3.2 2.5 2.1 1.0 3.3 3.0 2.8 0.7 3.5 1.7 1.3 4.7 2.1 6.7 9.4 13.3 10.3 5.9 6.4 8.6 11.5 8.0 6.6 9.4 7.9 13.9 3.2 5.2 10.1 110.9 9.1 28.3 7.9 13.6 1.0 15.8 21.0 42.5 8.6 6.6 1.8 0.0 1.9 156.9 41.6 9.8 6.2 4.2 54.2 5.2 11.9 62.8 280.4 2.5 5.0 5.8 8.8 12.2 21.5 8.8 31.5 10.4 6.0 9.6 0.0 1.3 56.4 12.2 8.1 18.9 4.0 4.4 27.6 1.8 2.8 5.8 12.8 54.6 4.5 4.6 5.9 35.4 6.0 52.8 18.8 2.8 16.4 22.5 1.4 6.6 20.6 7.6 2.4 13.2 9.1 8.4 2.3 81.0 13.3 34.0 18.5 RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 442.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 136.2" "Group enriched" "Detected in many" 12 "dendritic cells: 34.4;granulocytes: 136.2;monocytes: 45.5" "Cell line enhanced" "Detected in many" "BEWO: 134.0;CAPAN-2: 63.5;OE19: 56.7;SK-BR-3: 58.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" 9.3 49.7 2.2 20.3 1.9 9.6 24.7 1.8 3.0 15.3 44.9 61.0 68.4 3.5 23.1 42.2 17.7 17.9 1.3 2.8 2.3 67.6 34.5 21.0 8.2 6.0 3.2 2.2 25.9 27.8 3.2 20.1 4.9 33.2 50.5 0.4 59.4 13.4 0.5 9.0 64.1 4.7 4.1 14.7 64.6 6.7 5.7 4.4 49.5 1.1 11.4 22.6 15.5 6.8 31.9 47.8 0.0 1.8 0.2 0.0 134.0 0.8 1.6 0.1 0.6 28.3 63.5 0.2 23.0 1.2 3.8 14.2 0.9 11.8 0.3 0.2 7.6 0.0 3.1 7.9 0.6 0.3 0.3 0.8 6.0 0.1 0.1 1.8 0.0 0.0 1.8 7.0 0.1 18.1 0.2 1.1 13.5 56.7 2.4 0.2 0.0 34.7 46.8 41.6 1.6 0.3 17.3 58.4 0.3 14.8 23.9 9.0 0.0 0.5 1.9 0.3 1.0 23.5 37.7 4.1 5.0 3.9 0.2 0.5 45.5 0.5 0.2 33.1 0.3 5.9 0.2 0.1 34.4 5.4 0.4 0.1 136.2 0.5 26.2 14.1 0.2 16.9 2.2 1.9 1.8 3.0 2.8 2.3 6.0 3.2 4.9 4.1 5.7 6.8 1.1 80.1 116.6 0.7 21.2 58.9 75.2 42.9 95.0 0.1 145.7 63.5 1.9 75.8 92.2 112.2 0.0 99.6 16.3 442.8 64.6 90.6 1.3 132.6 9.5 6.0 121.9 2.5 2.5 115.4 84.3 7.7 174.8 143.7 7.0 8.7 23.6 140.4 92.6 1.7 1.9 234.2 59.0 138.8 92.8 2.6 2.5 119.9 37.4 82.4 80.6 0.3 1.0 2.5 0.8 108.0 228.1 1.2 40.1 164.7 218.1 143.6 118.3 0.1 0.0 1.4 5.1 2.6 10.4 178.1 75.4 262.6 4.8 16.9 203.8 295.4 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 RBP7 CRBPIV ENSG00000162444 "Retinol binding protein 7" Q96R05 1 9997206-10016021 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 401.0;breast: 394.6" "Cell type enriched" "Detected in many" 7 "Adipocytes: 3631.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 311.5;neutrophil: 344.7" "Group enriched" "Detected in many" 31 "granulocytes: 344.7;monocytes: 311.5" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;SK-MEL-30: 9.8;T-47d: 34.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA034749 Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Cytosol" "HPA034749: AB_10602084" "unprognostic (1.93e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (9.59e-2)" "unprognostic (2.31e-1)" "unprognostic (6.28e-2)" "unprognostic (1.39e-2)" "unprognostic (1.85e-1)" "unprognostic (1.05e-3)" "unprognostic (2.24e-1)" "unprognostic (1.46e-2)" "unprognostic (7.90e-2)" "unprognostic (5.07e-2)" "unprognostic (2.38e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.61e-2)" 401.0 15.0 20.7 8.9 27.0 28.6 394.6 23.8 38.3 22.6 23.4 15.0 2.6 20.4 4.2 34.4 14.7 51.6 86.6 20.4 22.4 72.9 9.6 8.8 8.3 23.7 24.0 12.7 11.9 68.9 16.7 15.9 23.7 18.6 4.4 5.0 22.3 8.1 16.0 35.4 11.5 14.9 23.5 112.1 17.2 9.2 22.4 12.6 36.2 24.9 5.6 23.6 27.9 36.4 0.0 0.6 0.3 0.0 0.0 0.5 0.0 0.0 0.0 2.5 0.9 2.5 3.2 0.0 13.0 1.3 0.0 0.0 0.1 1.0 4.4 0.0 2.8 0.0 0.1 1.3 1.6 0.0 0.0 0.0 2.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 3.4 0.0 0.0 0.0 0.7 0.0 0.2 0.5 2.6 0.2 9.8 3.5 34.8 2.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 311.5 2.8 0.4 138.4 0.2 0.1 0.0 0.1 10.6 0.2 0.2 0.1 344.7 0.0 68.3 2.0 0.7 96.8 20.7 27.0 23.8 38.3 20.4 22.4 23.7 24.0 23.7 23.5 22.4 36.4 3631.8 0.0 1.3 0.7 9.5 20.6 9.5 2.6 9.1 0.2 43.0 73.9 22.9 10.0 1.2 1.8 0.0 5.0 16.2 0.1 23.5 2.0 3.2 2.5 15.8 349.2 0.0 5.7 0.4 2.8 1.9 36.1 0.0 4.8 3.8 7.1 69.7 3.7 63.7 0.0 0.4 0.4 2.0 502.5 14.1 6.1 6.2 42.5 21.4 1.0 149.7 2.1 3.1 0.0 13.4 2.7 0.1 0.7 2.7 20.7 0.0 1.4 0.9 1.5 0.0 3.9 20.5 1.8 2.8 26.2 17.6 6.2 3.8 3.6 0.6 6.3 RCL1 "RNAC, RPCL1" ENSG00000120158 "RNA terminal phosphate cyclase like 1" Q9Y2P8 9 4792944-4885917 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.8" "Cell type enhanced" "Detected in many" "Early spermatids: 74.1;Hepatocytes: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "HDLM-2: 145.5;HEL: 375.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071308 Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA071308: AB_2686384" "prognostic favorable (5.48e-4)" "unprognostic (7.60e-3)" "unprognostic (7.55e-2)" "unprognostic (4.19e-2)" "unprognostic (1.07e-2)" "unprognostic (3.29e-1)" "prognostic favorable (8.02e-4)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.59e-2)" "prognostic favorable (2.40e-7)" "unprognostic (1.01e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-1)" "unprognostic (3.66e-2)" 37.2 13.4 5.8 9.0 7.8 44.3 21.7 6.5 7.3 9.4 8.2 7.5 4.1 8.3 9.9 10.4 10.6 6.3 6.6 5.9 8.0 12.3 245.8 13.1 15.0 8.4 7.9 17.6 64.6 8.7 7.0 13.8 8.8 7.0 7.5 3.8 6.8 7.1 14.4 21.1 8.0 7.7 8.3 9.2 10.4 13.8 8.1 9.7 8.2 8.6 12.5 12.5 10.6 10.2 23.3 27.6 10.3 16.5 15.0 10.1 27.3 10.8 12.0 19.9 16.8 13.9 13.4 45.2 7.4 9.7 22.1 14.4 48.0 32.5 22.8 145.5 24.2 375.0 33.5 28.1 21.5 34.1 28.9 22.4 18.2 19.0 28.7 11.2 19.7 32.4 38.9 28.0 12.0 30.4 27.8 57.8 35.7 27.7 11.0 34.2 13.8 24.2 24.3 25.9 29.6 24.3 13.6 20.0 15.8 20.4 18.9 39.8 13.9 11.6 13.3 16.6 34.0 11.5 35.3 48.1 21.3 20.8 8.1 16.2 1.6 4.3 5.7 2.5 7.0 8.7 6.5 7.7 4.3 11.5 8.7 9.0 0.6 12.1 1.3 7.4 5.9 3.7 5.8 7.8 6.5 7.3 5.9 8.0 8.4 7.9 8.8 8.3 8.1 10.2 10.9 6.4 6.8 18.9 14.7 25.5 21.8 11.9 25.0 5.4 9.3 8.0 10.6 11.5 7.8 3.7 0.0 39.8 8.5 3.0 25.4 12.4 74.1 8.3 8.8 12.1 3.0 68.4 14.1 11.5 16.6 11.9 8.6 5.7 14.5 16.7 16.1 183.4 17.7 5.0 15.9 6.4 6.1 11.3 6.2 39.7 23.0 7.6 3.6 36.5 9.7 9.2 5.2 18.1 34.3 10.6 3.7 37.6 14.3 18.1 3.2 13.7 14.0 7.0 13.1 19.1 10.2 18.2 18.4 18.6 21.2 35.4 8.9 12.1 8.9 16.6 RCVRN RCV1 ENSG00000109047 Recoverin P35243 17 9896320-9905271 "Plasma proteins, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 434 "retina: 463.8" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 1926.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "WM-115: 1.8" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA015783, CAB022363" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB022363: , HPA015783: AB_2669298" "unprognostic (1.65e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-2)" "unprognostic (1.32e-1)" "unprognostic (7.95e-3)" "unprognostic (4.82e-2)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (1.94e-4)" "unprognostic (1.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.41e-2)" "unprognostic (9.23e-2)" 0.1 0.0 0.6 0.0 0.6 0.0 0.0 0.0 1.0 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 463.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 1.0 0.7 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 230.5 0.0 0.0 0.5 0.0 0.0 0.0 475.4 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 11.5 0.0 0.0 1.5 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 107.7 0.7 0.0 0.0 0.0 0.9 0.7 2.5 0.5 1.8 0.0 0.1 393.9 0.0 0.5 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1926.6 0.0 1.7 0.3 0.1 0.5 0.0 0.3 0.1 0.1 0.0 0.0 0.0 RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Club cells: 131.7;Collecting duct cells: 204.1;Muller glia cells: 342.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 143.6;BJ: 107.4;CACO-2: 97.0;HDLM-2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" 43.3 6.2 4.2 23.4 5.3 3.3 10.5 4.1 4.1 18.2 16.0 16.6 32.4 14.1 3.9 19.8 7.8 30.2 11.6 4.9 5.9 43.8 41.0 13.6 11.0 11.5 6.8 5.0 34.5 8.4 26.8 36.3 6.4 21.5 15.2 86.3 39.2 13.1 6.9 8.3 30.7 14.9 5.8 7.2 24.8 16.6 20.4 6.1 6.5 8.2 8.8 69.2 11.3 6.7 13.8 39.2 4.3 17.9 143.6 10.5 39.0 107.4 17.4 4.1 6.8 97.0 38.6 9.6 13.9 60.4 6.3 35.6 19.6 15.5 8.4 110.7 49.0 17.0 37.6 30.1 5.6 8.2 18.0 6.3 19.6 16.5 15.3 18.3 15.6 9.4 20.0 13.7 7.0 6.1 8.5 3.4 5.2 84.0 19.0 7.4 4.4 5.8 28.2 19.4 2.6 3.4 9.1 66.3 5.5 5.4 13.1 4.2 24.0 6.3 10.6 28.9 8.3 8.8 10.0 7.8 5.0 7.3 14.7 1.2 0.1 0.2 0.3 0.1 0.2 0.1 0.3 0.4 0.2 0.0 0.6 0.3 0.1 0.0 0.1 0.0 0.2 0.1 4.2 5.3 4.1 4.1 4.9 5.9 11.5 6.8 6.4 5.8 20.4 6.7 14.5 12.8 29.8 3.6 2.5 13.5 9.7 75.6 16.5 3.2 29.1 25.5 9.1 25.8 131.7 204.1 22.9 19.1 11.2 25.5 3.9 16.3 80.6 38.3 50.0 9.7 4.2 1.3 1.4 17.6 23.8 44.6 49.5 71.5 2.5 1.2 3.3 49.2 20.9 3.3 1.0 16.8 40.7 5.4 7.8 9.9 2.8 10.0 17.8 6.5 1.9 342.1 3.1 4.5 2.0 56.9 31.5 3.8 6.4 41.2 47.7 22.6 44.2 16.2 0.0 11.4 20.5 11.0 8.0 24.7 13.9 42.0 7.1 1.6 24.2 17.7 RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA056686: AB_2683209, HPA078577: " "unprognostic (5.79e-2)" "unprognostic (3.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-2)" "unprognostic (8.71e-3)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" "unprognostic (8.98e-2)" "unprognostic (1.58e-2)" "unprognostic (4.32e-2)" "unprognostic (3.69e-2)" 14.4 14.5 10.6 8.3 10.8 5.4 12.6 11.0 12.4 10.1 15.7 14.6 11.6 14.2 12.2 9.8 11.9 9.4 29.8 10.5 10.8 14.0 18.5 11.8 12.5 10.8 10.5 10.0 14.1 18.7 11.3 13.0 11.3 13.3 10.4 8.3 10.7 11.0 28.1 9.6 11.4 12.0 11.1 11.5 14.6 11.5 10.7 12.5 11.1 27.1 9.5 15.5 10.2 11.7 28.6 8.9 7.3 6.0 21.8 22.9 24.7 16.8 17.7 15.2 15.0 6.9 14.6 28.2 9.7 10.3 19.7 15.3 10.8 19.9 17.6 15.6 28.8 10.8 10.6 21.4 18.6 13.7 14.1 17.5 19.9 14.8 22.9 21.2 14.2 11.2 19.9 9.2 25.2 9.2 11.8 23.7 19.9 21.9 24.1 16.5 20.1 12.1 29.9 18.4 11.2 19.3 9.3 20.4 25.8 15.4 10.1 7.2 14.4 21.5 13.1 16.6 20.6 26.0 23.1 20.8 15.1 9.0 17.1 1.4 1.4 6.5 3.3 1.7 5.5 7.3 3.9 4.9 1.9 11.6 5.5 4.5 0.5 3.1 1.7 6.1 5.1 1.3 10.6 10.8 11.0 12.4 10.5 10.8 10.8 10.5 11.3 11.1 10.7 11.7 21.7 16.0 12.8 0.0 36.1 24.5 31.0 27.9 31.3 23.5 20.1 24.5 55.6 32.9 20.9 16.5 6.2 44.6 34.8 20.6 31.3 37.8 27.4 27.4 19.7 19.4 13.2 18.7 0.0 35.3 50.3 38.5 20.4 19.7 12.7 16.4 20.3 30.0 24.2 15.2 0.0 27.1 20.3 17.2 14.6 13.6 66.8 15.4 23.2 0.0 23.2 31.3 29.9 0.0 0.0 27.0 36.3 44.8 15.6 45.1 23.3 38.1 18.8 22.4 32.9 28.5 29.6 79.5 30.6 18.9 18.6 45.7 27.1 30.9 29.2 27.3 RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 94.5;liver: 58.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Proximal enterocytes: 49.9;Rod photoreceptor cells: 62.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.5;ASC TERT1: 24.3;hTEC/SVTERT24-B: 15.3;hTERT-RPE1: 24.5;LHCN-M2: 15.4;U-87 MG: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" 94.5 1.8 2.2 4.1 2.5 1.0 34.2 2.2 2.6 2.5 3.5 13.6 18.5 4.2 7.8 3.1 4.6 4.2 9.2 2.0 2.2 9.0 58.9 1.9 1.8 2.7 2.5 2.1 3.5 0.3 1.7 0.6 2.4 4.4 4.4 3.2 3.3 2.2 6.1 2.7 15.5 19.5 2.5 2.2 5.9 2.4 2.8 0.9 2.7 7.6 0.7 5.5 2.2 3.4 0.7 1.4 0.8 0.5 28.5 24.3 0.6 3.8 4.2 0.7 1.4 0.5 7.9 1.0 0.7 2.1 0.2 0.3 0.3 0.1 0.6 1.0 1.3 0.1 2.0 2.1 0.8 0.1 0.3 10.5 1.0 15.3 0.1 24.5 0.3 0.5 0.2 1.3 15.4 0.7 0.4 0.2 0.3 3.7 2.3 0.6 0.4 0.5 0.2 0.8 0.2 1.1 0.2 0.5 3.4 0.2 0.7 0.6 0.5 1.5 1.5 1.1 0.9 1.1 0.5 0.2 26.7 0.4 0.3 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.2 0.3 0.2 0.5 0.0 0.0 2.2 2.5 2.2 2.6 2.0 2.2 2.7 2.5 2.4 2.5 2.8 3.4 2.5 9.6 2.2 0.0 4.6 1.9 4.5 3.9 0.6 24.3 2.7 5.0 3.9 10.0 2.4 1.8 62.6 2.2 5.3 23.5 1.9 2.1 0.8 1.8 2.9 3.7 11.5 0.0 0.0 2.6 1.2 3.9 11.2 1.5 0.0 4.9 3.6 18.4 0.6 16.8 0.0 10.3 0.0 4.5 7.9 2.3 13.4 2.3 5.4 0.0 4.7 8.2 12.3 0.0 0.0 3.6 18.6 6.8 0.7 3.2 49.9 13.0 4.7 62.9 13.1 14.0 9.3 3.9 6.4 0.8 1.7 1.5 4.8 5.3 15.9 3.1 RDX DFNB24 ENSG00000137710 Radixin P35241 11 109864295-110296712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 155.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, HPA000763, CAB037312" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 38000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Nucleoplasm "CAB037312: AB_261933, HPA000263: AB_1856043, HPA000763: AB_1856042" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (3.85e-1)" "unprognostic (2.74e-2)" "unprognostic (6.93e-2)" "unprognostic (9.82e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.91e-2)" "unprognostic (6.91e-2)" "unprognostic (1.32e-3)" "unprognostic (6.47e-2)" "unprognostic (4.14e-3)" "unprognostic (5.43e-2)" "unprognostic (4.40e-1)" "unprognostic (1.24e-1)" "unprognostic (1.08e-3)" 40.3 155.0 38.0 17.4 57.7 12.0 16.4 50.0 42.7 32.1 32.8 15.2 6.8 28.8 12.9 27.4 19.7 27.2 41.0 35.1 44.7 50.2 68.5 48.8 11.4 52.7 48.2 52.8 52.7 33.2 7.6 35.3 54.3 25.4 11.1 19.2 20.8 26.0 82.1 11.9 7.4 35.0 45.1 26.6 15.0 33.7 47.7 14.3 45.7 59.7 14.6 27.1 10.1 77.6 69.6 35.3 137.3 54.8 78.8 87.4 79.3 85.8 47.6 54.3 59.2 99.7 115.4 0.1 127.4 104.7 84.9 61.5 77.3 80.4 80.5 41.9 44.2 51.5 107.7 74.1 73.6 19.0 33.2 89.7 45.6 68.0 120.1 89.3 149.8 11.1 73.5 29.5 127.0 120.0 11.0 15.6 44.0 4.0 58.4 31.2 96.8 30.1 68.1 33.5 37.2 40.5 148.5 65.9 52.7 102.5 85.0 29.9 92.6 89.5 66.8 43.9 67.4 9.5 17.3 65.9 34.2 11.3 210.9 29.5 14.8 22.0 11.6 12.5 15.5 11.5 10.2 8.8 12.8 8.3 6.8 5.8 2.0 17.6 9.9 10.3 22.0 8.4 38.0 57.7 50.0 42.7 35.1 44.7 52.7 48.2 54.3 45.1 47.7 77.6 248.8 484.0 98.8 53.5 30.0 56.1 51.8 124.6 56.9 85.9 47.4 45.7 159.3 70.1 77.9 75.4 43.8 122.1 21.6 17.7 109.5 128.1 15.5 109.1 117.2 289.2 22.2 104.8 27.1 423.4 189.8 88.4 19.9 135.3 67.2 132.0 319.2 260.1 85.1 101.0 57.6 7.3 61.1 103.2 59.9 43.6 275.2 71.6 72.9 42.2 135.4 77.0 36.0 68.3 229.4 134.3 22.1 266.7 36.1 65.9 0.1 236.9 52.2 94.8 124.9 74.0 143.8 73.9 257.4 52.8 40.5 227.3 29.2 229.9 11.8 45.9 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 RELL1 ENSG00000181826 "RELT like 1" Q8IUW5 4 37590800-37686376 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Microglial cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 59.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013377 Approved Supported "Plasma membrane,Microtubules" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Microtubules" "HPA013377: AB_1844403" "unprognostic (1.70e-1)" "unprognostic (1.70e-1)" "unprognostic (4.78e-2)" "unprognostic (5.30e-2)" "unprognostic (6.80e-2)" "unprognostic (7.28e-2)" "unprognostic (7.35e-2)" "unprognostic (2.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (7.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" 13.5 2.4 10.6 4.9 15.5 25.6 7.8 20.1 14.9 5.1 9.3 8.3 6.2 5.5 2.7 6.4 5.1 6.1 6.0 8.0 13.3 3.9 4.8 6.6 4.7 29.7 19.3 3.5 2.3 1.5 1.4 6.1 27.7 3.0 6.6 3.1 3.5 3.8 15.8 12.4 5.5 6.0 24.4 7.3 12.3 1.6 20.1 3.7 12.5 4.3 4.8 7.8 4.1 39.7 4.8 5.1 12.9 11.1 10.8 6.2 10.8 8.0 6.9 5.5 7.2 16.8 5.7 1.3 5.7 6.9 9.8 4.3 4.1 7.2 9.6 0.2 2.1 1.8 4.7 18.2 8.1 6.0 4.5 10.6 10.2 7.5 8.2 3.4 24.9 3.3 3.1 5.0 6.4 4.4 7.5 8.3 3.2 6.9 1.5 2.5 45.0 2.2 13.2 5.9 2.9 8.5 6.1 6.6 10.6 3.2 18.0 3.2 29.6 13.8 8.7 10.1 9.5 2.5 2.6 7.3 11.7 12.8 11.4 0.8 15.2 27.4 5.1 5.7 6.3 0.7 6.2 4.9 8.5 0.2 5.3 7.0 59.3 7.7 5.5 9.8 5.5 5.1 10.6 15.5 20.1 14.9 8.0 13.3 29.7 19.3 27.7 24.4 20.1 39.7 30.5 9.6 3.1 16.3 2.9 3.3 2.5 1.7 10.8 0.4 8.1 9.5 2.1 5.7 3.9 0.0 0.0 1.4 9.8 8.4 0.0 3.1 6.5 5.5 9.9 14.4 1.2 3.4 3.3 8.6 3.6 10.7 22.4 2.4 2.5 0.5 6.4 0.9 2.6 3.3 2.4 1.6 0.0 3.2 2.7 8.1 3.7 9.2 1.8 36.5 4.1 4.0 0.0 22.6 12.5 10.3 2.9 6.0 15.5 2.7 6.7 0.2 3.3 1.4 13.1 18.8 16.4 0.8 0.3 5.5 4.7 5.2 10.6 5.1 1.1 3.8 REM1 "GES, REM" ENSG00000088320 "RRAD and GEM like GTPase 1" O75628 20 31475288-31484895 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.1" "Cell type enhanced" "Detected in some" "Adipocytes: 7.7;Peritubular cells: 11.7;Sertoli cells: 59.2;Smooth muscle cells: 28.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 32 "WM-115: 22.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.6" HPA049821 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049821: AB_2680898" "unprognostic (6.16e-2)" "unprognostic (3.17e-3)" "unprognostic (2.62e-1)" "unprognostic (9.65e-2)" "unprognostic (6.03e-3)" "unprognostic (1.84e-2)" "unprognostic (4.39e-1)" "unprognostic (2.15e-1)" "unprognostic (2.48e-1)" "unprognostic (3.88e-2)" "unprognostic (4.77e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (7.79e-2)" "unprognostic (4.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.06e-2)" 13.9 2.2 1.2 1.7 1.1 0.0 7.5 0.9 2.1 20.1 1.3 6.5 1.3 10.5 7.2 2.0 10.0 2.2 6.2 1.0 1.0 3.2 0.8 4.6 3.0 1.0 1.1 3.9 1.1 1.1 2.7 2.1 1.1 5.5 1.0 0.0 1.6 4.9 3.3 3.2 3.7 3.2 0.9 2.5 2.4 1.4 1.3 0.7 4.8 2.4 1.5 4.8 9.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.9 2.1 1.0 1.0 1.0 1.1 1.1 0.9 1.3 1.0 7.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.4 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 7.1 2.3 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.2 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.6 5.6 0.3 3.6 1.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.8 0.0 59.2 0.6 28.1 0.0 0.2 0.1 0.9 0.0 0.1 1.5 0.0 0.0 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 RETREG1 "FAM134B, FLJ20152, JK1" ENSG00000154153 "Reticulophagy regulator 1" Q9H6L5 5 16473038-16617038 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 91.4;skeletal muscle: 141.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Cytotrophoblasts: 53.7;Exocrine glandular cells: 59.3;Glandular and luminal cells: 197.7;Pancreatic endocrine cells: 51.5;Proximal tubular cells: 152.8" "Cancer enhanced" "Detected in all" "renal cancer: 28.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.3;T-cells: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 26.0;GAMG: 20.3;HSkMC: 28.8;MOLT-4: 20.4;RPTEC TERT1: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012077 Supported "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA012077: AB_2668621" "unprognostic (1.63e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-2)" "unprognostic (9.17e-3)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (4.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "prognostic favorable (5.25e-10)" "unprognostic (3.75e-1)" "unprognostic (9.96e-2)" "unprognostic (5.62e-2)" "unprognostic (2.58e-1)" 15.6 3.5 20.6 6.6 26.4 2.0 13.6 23.9 33.2 13.2 21.6 24.6 12.6 4.0 5.2 3.6 7.5 13.4 91.4 19.4 22.1 61.0 44.2 9.3 6.4 27.2 25.2 2.1 37.7 30.1 9.9 13.2 27.8 11.1 32.4 7.5 5.2 5.0 141.8 10.0 25.6 2.6 23.6 2.3 10.9 12.3 25.0 20.6 6.7 81.9 4.3 2.3 5.2 37.6 1.3 0.5 0.1 3.5 26.0 3.2 15.1 0.1 3.5 3.1 4.1 2.3 0.1 0.3 2.4 0.0 20.3 3.9 7.8 0.8 1.0 4.1 3.4 0.0 10.6 0.0 0.1 5.3 0.0 28.8 11.7 0.6 3.1 7.5 0.0 15.4 0.0 0.1 1.2 1.0 20.4 0.1 0.8 3.4 0.6 3.2 0.0 1.2 26.2 0.9 17.4 2.0 1.0 1.1 13.1 1.9 5.9 2.4 0.0 2.4 0.2 6.4 3.1 0.7 0.0 0.0 14.9 18.0 6.5 2.3 0.1 0.0 0.2 0.0 0.6 0.0 0.6 0.3 0.0 0.3 1.7 1.0 0.9 0.0 0.0 0.0 0.8 0.2 20.6 26.4 23.9 33.2 19.4 22.1 27.2 25.2 27.8 23.6 25.0 37.6 4.2 73.7 8.6 0.0 3.4 0.0 0.0 0.0 0.0 0.0 33.3 19.0 0.0 0.0 9.9 44.1 0.0 53.7 2.2 0.0 17.6 31.1 0.0 33.5 45.2 1.2 0.0 0.0 0.0 59.3 2.0 7.8 0.0 197.7 1.3 3.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.8 0.0 0.0 152.8 19.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 10.9 8.1 0.3 0.0 0.0 RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85341955-85354531 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 247.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Proximal enterocytes: 249.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007961, HPA046513" Uncertain Uncertain Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA007961: AB_1079802, HPA046513: AB_2679680" "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (5.84e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "prognostic favorable (4.23e-4)" "unprognostic (1.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.95e-10)" "unprognostic (2.73e-2)" "unprognostic (5.34e-1)" "unprognostic (8.24e-3)" "unprognostic (9.90e-2)" 247.0 52.3 16.5 17.6 20.9 3.8 63.9 19.8 15.8 18.9 27.3 89.6 167.0 16.0 38.4 36.9 15.7 32.0 20.3 14.9 20.0 54.9 115.9 24.6 11.7 21.0 20.0 17.0 37.5 36.9 7.2 11.6 20.0 32.5 73.5 9.5 27.8 23.6 68.3 48.8 142.4 22.0 19.2 11.7 60.9 14.6 19.9 12.2 47.4 55.1 19.9 19.0 23.7 23.7 52.7 30.1 16.8 40.0 197.8 37.0 22.1 37.8 46.5 22.5 31.5 20.9 36.2 18.5 30.3 29.6 17.9 42.6 22.9 65.6 21.6 22.8 15.9 9.0 23.5 50.6 47.6 17.9 19.3 48.6 87.2 28.7 38.1 51.4 37.6 15.4 9.7 43.1 42.0 11.0 12.5 9.0 5.6 52.6 36.2 8.1 33.7 23.9 39.1 30.1 8.3 13.8 31.4 59.9 101.8 11.2 28.2 2.9 30.0 25.3 13.8 23.5 19.9 23.0 22.9 7.2 30.9 20.5 17.6 0.0 3.8 1.8 4.8 4.0 6.2 2.6 3.5 6.0 4.0 1.5 2.5 2.5 3.7 5.1 8.7 2.7 4.2 3.4 16.5 20.9 19.8 15.8 14.9 20.0 21.0 20.0 20.0 19.2 19.9 23.7 7.3 28.9 29.6 5.9 4.5 11.3 10.8 18.6 12.5 3.7 13.0 7.9 21.7 21.5 15.5 12.9 18.8 10.9 4.3 264.9 0.0 23.7 27.6 9.7 6.8 9.7 10.8 2.5 5.7 36.1 6.5 9.0 56.1 16.6 10.8 5.5 7.5 54.7 9.9 11.8 4.5 45.0 8.2 10.4 8.6 60.0 14.6 7.4 30.2 7.5 8.3 8.3 10.3 6.6 12.1 32.7 79.2 12.4 10.3 11.8 249.9 17.8 11.9 4.9 0.0 7.7 8.8 2.9 3.1 24.9 14.9 8.5 7.7 9.9 56.6 9.8 REXO5 NEF-sp ENSG00000005189 "RNA exonuclease 5" Q96IC2 16 20806429-20849665 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 343.8" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 15 "basophil: 86.7" "Lineage enriched" "Detected in many" 39 "granulocytes: 86.7" "Cell line enhanced" "Detected in many" "K-562: 44.7;U-266/70: 42.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040755, HPA040868, HPA066145" Approved Approved "Nuclear membrane,Nucleoli,Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane" "Nucleoli, Endoplasmic reticulum" "HPA040755: AB_10965790, HPA040868: AB_10963549, HPA066145: " "unprognostic (2.39e-1)" "unprognostic (2.09e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (6.24e-2)" "unprognostic (2.26e-1)" "unprognostic (1.80e-2)" "unprognostic (8.24e-2)" "unprognostic (4.72e-2)" "unprognostic (2.42e-4)" "unprognostic (1.01e-2)" "unprognostic (8.23e-2)" "unprognostic (2.00e-1)" "unprognostic (6.93e-2)" 2.3 1.8 1.4 1.8 1.4 11.6 3.6 1.6 2.0 1.7 0.4 2.1 2.9 2.2 1.2 2.3 4.2 1.6 3.4 1.4 2.3 1.2 1.8 1.0 2.9 1.7 1.1 1.9 1.7 40.0 0.9 1.5 1.6 5.3 3.0 4.2 1.7 1.3 1.0 2.2 2.1 2.7 0.8 1.0 5.0 343.8 2.2 7.4 0.9 1.3 2.6 2.0 1.6 2.1 11.3 6.5 10.1 4.5 4.2 7.5 3.4 7.6 8.4 8.2 8.9 4.7 10.0 7.0 11.5 6.7 5.7 5.7 7.7 3.4 8.5 6.5 4.9 11.7 10.2 6.7 0.8 17.2 16.4 3.8 1.5 9.7 12.4 3.5 2.8 0.0 44.7 29.8 20.5 15.1 2.8 13.5 5.5 4.6 6.6 14.0 18.8 12.6 2.5 4.0 8.6 9.7 7.3 9.6 2.4 2.9 16.2 14.8 1.4 6.1 5.4 8.2 9.3 42.5 31.1 2.7 12.6 22.3 5.6 86.7 0.4 5.7 0.3 0.1 0.4 0.0 0.4 0.4 0.7 0.0 0.1 0.3 0.4 2.2 0.2 0.2 1.8 0.4 1.4 1.4 1.6 2.0 1.4 2.3 1.7 1.1 1.6 0.8 2.2 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.4 0.0 0.0 1.3 0.0 0.0 3.2 0.8 0.0 0.0 1.6 0.0 2.8 1.6 0.6 0.0 0.0 0.0 1.5 2.4 1.5 0.0 1.7 1.3 26.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.6 1.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.5 4.7 0.0 0.0 RFTN1 "FLJ23866, KIAA0084, MIG2, Raftlin" ENSG00000131378 "Raftlin, lipid raft linker 1" Q14699 3 16313574-16514026 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 87.6;monocytes: 143.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 151.7;Daudi: 122.9;HDLM-2: 177.5;SH-SY5Y: 132.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048725 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "HPA048725: AB_2680502" "unprognostic (1.98e-1)" "unprognostic (5.82e-2)" "unprognostic (1.44e-1)" "unprognostic (1.61e-1)" "unprognostic (5.92e-2)" "unprognostic (1.19e-2)" "unprognostic (1.87e-1)" "unprognostic (7.55e-3)" "unprognostic (9.99e-3)" "unprognostic (7.24e-2)" "unprognostic (2.75e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.29e-7)" "unprognostic (6.19e-2)" "unprognostic (1.49e-2)" "unprognostic (2.88e-2)" "unprognostic (2.81e-1)" 57.2 11.2 15.1 44.7 18.3 13.3 33.2 13.6 22.7 28.2 15.8 15.2 9.3 36.6 4.9 14.5 26.0 15.4 44.7 18.3 20.2 18.4 24.8 46.9 117.0 21.7 14.9 30.4 4.7 9.0 7.4 51.0 16.1 16.4 14.1 11.4 11.3 10.3 25.5 17.1 22.8 31.3 13.9 45.5 11.8 7.0 15.2 73.2 53.4 26.6 117.4 26.2 14.5 17.5 0.1 2.9 5.3 0.0 151.7 75.7 7.7 38.8 65.9 19.3 15.6 21.5 1.0 122.9 18.6 71.2 4.3 0.6 0.1 51.4 25.5 177.5 9.0 19.8 4.9 0.3 78.6 14.7 10.8 111.3 3.4 60.7 19.0 67.5 40.5 19.8 0.5 0.4 47.0 6.6 31.3 5.0 3.5 0.0 1.4 29.6 60.8 15.0 8.0 0.1 0.1 132.6 1.3 1.3 7.2 7.4 0.2 12.2 59.9 47.3 23.0 47.8 16.8 0.4 0.5 82.5 22.0 38.6 19.2 56.0 19.6 13.2 35.3 46.4 18.1 16.3 27.2 37.6 33.6 32.0 18.4 27.8 1.2 80.1 81.7 25.8 60.4 38.3 15.1 18.3 13.6 22.7 18.3 20.2 21.7 14.9 16.1 13.9 15.2 17.5 37.9 22.4 40.0 8.1 51.2 6.5 0.3 2.3 0.0 3.2 0.7 1.5 14.3 5.7 6.9 0.0 0.0 6.2 61.1 0.1 0.0 7.2 38.0 2.6 51.8 34.4 1.2 10.3 87.6 0.9 1.1 32.4 3.1 2.0 24.7 2.1 36.0 7.2 10.5 0.0 16.5 0.0 0.0 17.6 63.6 12.2 18.6 27.0 10.6 19.7 143.8 37.2 64.9 3.0 2.4 0.9 0.1 8.6 43.2 0.6 0.0 0.4 3.3 3.2 0.0 28.2 35.2 2.8 2.4 0.8 5.1 2.5 39.5 12.6 0.3 0.4 RFX6 "dJ955L16.1, MGC33442, RFXDC1" ENSG00000185002 "Regulatory factor X6" Q8HWS3 6 116877212-116932161 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 4.5;intestine: 2.2;pancreas: 2.3;stomach 1: 6.5" "Cell type enriched" "Detected in some" 14 "Enteroendocrine cells: 68.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEK 293: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA037696 Approved NA NA "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA037696: AB_2675616" "unprognostic (2.92e-1)" "unprognostic (4.66e-2)" "unprognostic (2.49e-2)" "unprognostic (1.55e-1)" "prognostic favorable (3.59e-4)" "unprognostic (2.59e-2)" "unprognostic (1.63e-1)" "unprognostic (1.25e-1)" 0.0 4.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 6.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 68.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 3.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.3 0.0 0.0 0.4 0.0 RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Excitatory neurons: 176.1;Inhibitory neurons: 141.8;Kupffer cells: 109.1;Oligodendrocytes: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;HSkMC: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" 24.7 16.8 22.7 19.9 25.3 1.6 17.1 17.3 27.0 18.6 21.5 11.3 8.7 18.0 6.3 10.6 15.2 22.5 17.0 27.1 21.7 28.6 16.2 20.9 22.9 23.7 20.7 19.2 6.8 8.9 9.5 16.1 17.4 13.2 12.8 15.7 7.7 11.6 2.7 8.9 10.6 22.2 21.1 45.4 6.9 14.7 23.9 8.7 9.1 7.7 10.1 18.7 8.9 28.5 0.3 1.5 26.3 4.0 35.0 16.1 26.7 12.4 20.6 5.5 6.8 12.2 0.7 0.3 11.3 8.8 4.3 0.6 1.8 3.1 5.4 0.4 1.9 0.2 2.6 12.6 9.3 0.4 1.5 54.9 0.7 14.0 3.3 26.2 20.8 2.7 0.0 19.6 11.8 0.1 2.9 0.2 9.6 0.9 0.7 23.7 1.7 24.3 1.5 7.5 3.3 7.9 3.9 4.2 2.1 8.5 0.2 0.3 15.3 7.9 3.1 24.7 6.8 2.0 0.5 0.1 8.3 0.3 22.2 0.0 0.8 0.0 0.0 2.1 0.1 0.0 0.3 0.0 0.9 0.0 0.4 0.2 0.0 0.0 0.8 0.0 0.2 0.5 22.7 25.3 17.3 27.0 27.1 21.7 23.7 20.7 17.4 21.1 23.9 28.5 9.4 9.6 12.3 133.5 1.6 8.2 2.2 2.5 5.2 5.1 6.7 4.6 8.7 5.7 9.0 5.5 0.0 5.1 0.6 2.6 5.9 4.0 13.8 7.9 23.2 19.7 0.0 0.4 176.1 0.9 2.6 22.0 3.6 24.1 3.8 11.0 41.4 2.6 43.3 8.4 141.8 0.8 4.1 109.1 50.4 17.6 13.1 43.7 5.4 76.8 1.7 23.0 0.0 38.7 184.3 1.0 0.1 20.7 0.1 3.5 2.8 30.1 14.2 2.0 26.3 1.2 9.7 4.0 2.5 5.8 4.7 5.2 2.2 13.1 0.6 2.9 RGS6 ENSG00000182732 "Regulator of G protein signaling 6" P49758 14 71932429-72566530 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Astrocytes: 97.3;Early spermatids: 173.5;Excitatory neurons: 652.7;Inhibitory neurons: 256.1;Late spermatids: 298.0" "Group enriched" "Detected in some" 7 "glioma: 3.1;thyroid cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 11.5;Karpas-707: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003067 Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Vesicles" "HPA003067: AB_1079807" "unprognostic (7.18e-2)" "unprognostic (7.78e-2)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (5.61e-2)" "unprognostic (3.80e-2)" "unprognostic (1.24e-4)" "unprognostic (7.83e-2)" "unprognostic (2.03e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-2)" "unprognostic (8.64e-2)" "unprognostic (5.11e-2)" "unprognostic (8.06e-3)" "unprognostic (2.10e-1)" "unprognostic (3.68e-2)" 4.7 0.2 1.1 0.6 2.2 1.4 4.0 0.6 8.6 4.9 0.0 1.0 0.3 1.4 2.6 0.4 2.2 1.2 11.2 3.5 2.8 2.6 0.1 0.9 0.1 19.2 16.0 1.2 0.2 8.1 1.7 3.0 20.2 0.4 1.0 1.7 0.8 1.4 1.1 0.9 0.8 1.3 5.4 0.9 0.4 10.6 6.4 0.3 5.7 0.8 0.5 0.7 0.9 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 40.1 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.3 1.2 1.1 2.2 0.6 8.6 3.5 2.8 19.2 16.0 20.2 5.4 6.4 3.4 5.8 0.0 0.0 97.3 0.2 0.3 0.0 0.0 0.0 2.2 2.1 2.4 22.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 173.5 2.8 0.9 2.6 0.0 5.3 652.7 0.2 0.1 3.1 0.0 7.1 0.0 0.4 0.0 0.0 0.2 0.0 256.1 0.0 0.0 0.0 0.0 298.0 1.8 8.3 0.0 44.0 5.1 0.0 0.0 36.2 8.9 0.0 0.0 7.5 0.2 0.0 0.0 0.4 0.0 0.4 13.1 0.4 18.6 2.3 1.3 0.2 0.1 0.8 0.5 0.1 0.0 0.7 RHOBTB3 KIAA0878 ENSG00000164292 "Rho related BTB domain containing 3" O94955 5 95713522-95824383 "Predicted intracellular proteins" Transport Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Leydig cells: 397.3;Peritubular cells: 314.8;Skeletal myocytes: 347.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.3" "Group enriched" "Detected in many" 4 "granulocytes: 7.3;T-cells: 1.9" "Cell line enhanced" "Detected in many" "EFO-21: 250.6;HaCaT: 332.7;SuSa: 315.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000265 Uncertain Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA000265: " "unprognostic (1.68e-1)" "unprognostic (9.60e-2)" "unprognostic (5.62e-2)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "unprognostic (3.39e-2)" "unprognostic (7.37e-2)" "unprognostic (4.28e-1)" "unprognostic (6.00e-3)" "unprognostic (9.29e-2)" "unprognostic (9.15e-2)" "unprognostic (3.64e-1)" "unprognostic (1.56e-3)" "unprognostic (7.01e-3)" "unprognostic (1.15e-1)" "unprognostic (3.23e-1)" "unprognostic (8.21e-2)" 79.8 38.3 58.8 11.9 81.2 8.1 23.8 59.1 64.2 27.7 12.1 22.5 14.8 13.1 27.0 17.0 16.5 19.7 33.7 55.6 47.8 28.3 21.7 16.9 6.8 81.5 56.4 83.0 111.1 55.6 13.2 54.0 52.1 28.8 20.8 29.0 41.9 20.6 29.8 13.2 16.6 20.6 50.6 11.3 22.6 21.4 64.5 8.3 19.9 32.7 2.3 25.5 13.4 67.4 53.7 20.4 51.1 55.1 188.4 108.5 0.5 91.0 86.4 34.7 54.0 96.5 9.6 0.2 250.6 45.8 88.5 332.7 27.7 6.6 59.4 2.2 36.6 18.3 185.8 28.9 148.6 4.3 25.5 176.6 4.8 52.0 0.9 147.6 27.0 15.5 74.7 13.4 139.3 14.8 5.8 14.9 19.7 33.4 33.4 8.2 100.3 6.5 29.1 35.6 90.3 118.9 71.8 31.0 85.7 315.9 23.6 26.3 44.5 46.1 195.7 31.1 35.8 13.5 28.3 2.7 14.8 1.1 76.8 0.1 0.6 7.3 1.9 0.3 0.7 0.5 1.4 1.6 0.1 0.1 1.8 0.4 0.4 0.3 1.0 0.8 0.8 0.6 58.8 81.2 59.1 64.2 55.6 47.8 81.5 56.4 52.1 50.6 64.5 67.4 23.4 176.3 13.3 229.9 5.4 10.8 65.8 25.9 13.6 68.3 81.2 44.1 79.4 44.3 49.8 141.6 20.9 62.2 15.7 21.4 60.7 69.7 11.4 55.3 118.6 15.7 92.0 32.6 35.2 111.0 139.7 201.3 3.1 76.8 100.1 178.3 14.3 77.3 33.3 6.7 57.3 66.9 14.2 23.0 11.6 22.1 397.3 20.4 42.7 30.0 3.7 270.3 71.1 117.6 64.8 40.7 70.1 314.8 7.1 53.8 19.9 3.1 33.7 35.9 32.9 347.6 99.2 4.6 8.8 10.1 27.4 115.2 9.8 177.2 84.5 102.2 RHOG "ARHG, MGC125835, MGC125836" ENSG00000177105 "Ras homolog family member G" P84095 11 3826978-3840959 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 273.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 365.2;Langerhans cells: 356.6;monocytes: 391.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 625.4" "Low region specificity" "Detected in all" HPA039871 Enhanced NA NA 86000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "HPA039871: AB_10673428" "unprognostic (2.39e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (2.26e-2)" "unprognostic (1.35e-1)" "unprognostic (4.21e-2)" "unprognostic (4.27e-3)" "unprognostic (7.28e-2)" "unprognostic (1.71e-2)" "unprognostic (3.28e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-1)" "prognostic unfavorable (9.49e-8)" "unprognostic (9.38e-2)" "unprognostic (8.98e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" 61.2 39.5 62.6 82.5 90.0 273.1 45.7 84.0 70.5 46.2 56.0 50.1 44.7 46.7 19.5 82.6 44.6 34.4 47.0 60.4 71.2 35.6 39.3 87.5 85.2 91.1 83.6 38.0 30.5 18.3 25.4 43.5 91.7 36.8 28.3 4.3 39.1 28.4 53.0 50.1 64.2 39.2 76.5 168.4 42.2 15.3 81.7 68.0 29.0 27.0 67.3 56.5 48.6 107.2 74.1 99.0 19.8 34.1 74.8 84.1 21.4 48.1 59.6 73.7 77.8 61.0 78.7 74.9 24.9 89.2 74.9 85.3 31.2 68.0 47.6 66.6 75.3 170.3 44.7 57.9 75.3 150.0 625.4 82.0 61.1 46.1 44.4 42.6 85.8 99.5 101.3 80.8 61.0 86.5 126.5 206.8 31.5 53.4 78.8 63.7 21.4 44.4 53.1 50.9 10.6 26.7 34.0 77.7 39.4 22.5 41.0 111.6 67.2 88.8 44.5 95.3 57.2 44.8 66.4 42.5 81.0 135.8 50.6 441.3 351.1 739.9 114.8 468.1 101.8 79.8 125.6 128.7 310.8 78.1 87.4 101.6 981.2 97.9 561.9 77.2 206.6 346.7 62.6 90.0 84.0 70.5 60.4 71.2 91.1 83.6 91.7 76.5 81.7 107.2 38.4 19.2 21.5 2.9 109.0 68.7 62.4 35.3 22.8 0.9 24.0 26.3 6.6 20.0 26.9 20.2 0.0 100.4 105.2 99.1 15.6 67.2 1.6 10.2 20.6 58.5 16.2 71.9 1.9 56.6 82.1 38.2 22.4 19.1 200.0 62.8 43.5 19.5 247.7 3.3 1.9 26.7 14.2 365.2 356.6 3.6 38.5 250.6 53.4 8.4 391.7 18.0 166.9 3.0 45.9 86.6 143.6 36.1 45.1 70.4 135.4 24.8 9.7 3.0 19.7 21.6 34.0 10.2 23.9 45.1 59.5 124.2 124.8 11.2 28.9 95.7 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117171 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 496.2;liver: 1536.9" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1579.1" "Group enriched" "Detected in all" 5 "liver cancer: 162.2;renal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 191.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favorable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 50.1 48.4 93.1 11.4 96.4 7.5 19.1 95.5 131.7 11.2 83.8 24.5 30.5 8.4 22.7 14.3 9.4 22.7 32.3 89.2 95.0 496.2 1536.9 9.5 10.1 91.6 97.8 23.4 27.0 24.6 10.0 10.8 95.5 19.3 24.6 26.6 16.4 11.6 40.0 10.6 21.8 10.8 92.6 7.4 24.8 17.2 100.0 11.2 15.9 41.0 12.3 15.5 7.9 91.0 44.0 37.5 29.3 36.6 65.5 50.4 33.0 39.7 28.0 26.4 31.0 51.4 28.4 62.5 49.6 29.4 34.5 30.8 65.4 56.9 52.5 22.3 28.6 45.0 25.6 55.6 29.9 17.6 7.0 44.4 19.5 36.6 39.9 32.4 34.2 65.3 82.7 12.9 35.5 57.8 35.6 50.1 47.0 191.4 67.8 41.0 21.7 18.4 64.6 31.6 32.2 15.7 25.5 17.4 29.2 37.4 44.5 23.5 20.9 20.6 12.5 33.7 16.3 31.2 46.1 30.9 35.0 39.0 13.2 0.2 9.0 5.6 6.6 7.8 8.7 13.8 9.4 10.1 11.1 11.5 12.0 13.0 1.9 10.3 8.3 8.5 13.9 8.1 93.1 96.4 95.5 131.7 89.2 95.0 91.6 97.8 95.5 92.6 100.0 91.0 7.8 25.6 22.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 13.8 15.1 0.0 0.0 1.8 47.8 0.0 31.1 3.2 0.0 285.7 19.7 0.0 25.1 12.3 5.0 0.0 0.0 0.0 8.5 29.9 7.9 0.0 9.4 2.5 17.7 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.8 0.0 0.0 1579.1 5.8 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 14.4 6.3 22.3 0.0 0.0 RILP FLJ31193 ENSG00000167705 "Rab interacting lysosomal protein" Q96NA2 17 1646145-1649866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.5;skeletal muscle: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.4;Proximal enterocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.5;eosinophil: 1.0;intermediate monocyte: 1.2;myeloid DC: 2.4;neutrophil: 3.3;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.3;monocytes: 3.5" "Cell line enhanced" "Detected in many" "HEL: 40.6;HMC-1: 19.5;K-562: 15.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 18000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" "prognostic favorable (7.97e-4)" "unprognostic (7.93e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-2)" "unprognostic (8.84e-3)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "prognostic favorable (8.51e-5)" "unprognostic (2.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.00e-1)" "prognostic favorable (7.12e-4)" 17.4 18.0 3.4 0.8 3.3 8.1 15.6 3.2 5.1 5.0 10.7 15.5 10.5 5.9 0.6 5.4 6.9 1.1 60.5 3.1 3.3 15.3 29.1 13.1 1.0 3.7 3.4 3.2 10.4 1.8 4.5 0.8 3.4 6.0 1.4 0.4 11.5 1.2 48.1 6.3 13.0 0.9 2.9 15.1 13.5 3.2 3.8 0.3 29.6 8.3 0.4 11.3 5.1 3.2 2.3 1.6 0.2 1.7 1.1 2.7 7.7 1.5 1.0 1.6 0.9 3.6 0.5 0.4 5.2 1.2 0.5 5.5 0.2 0.2 0.3 0.2 3.6 40.6 0.5 4.6 1.7 0.3 19.5 2.2 0.7 0.4 0.0 0.8 1.4 0.3 15.8 0.4 0.5 2.2 1.4 3.1 0.4 0.4 8.1 5.8 0.0 1.1 0.0 1.3 0.1 0.6 0.8 1.0 2.0 0.2 1.0 0.3 7.8 0.5 1.0 1.9 1.5 0.3 0.5 0.0 3.0 1.8 0.3 0.3 3.5 1.0 0.1 1.2 0.1 0.3 0.2 0.1 2.4 0.0 0.2 0.0 3.3 0.5 0.2 1.3 0.1 0.7 3.4 3.3 3.2 5.1 3.1 3.3 3.7 3.4 3.4 2.9 3.8 3.2 42.6 19.2 17.7 3.3 3.2 8.8 13.3 7.5 2.8 1.6 11.1 13.1 59.9 17.2 8.9 7.3 0.0 15.8 12.1 101.4 50.9 29.2 0.1 3.2 5.1 21.9 3.0 65.9 3.1 25.4 9.4 12.9 24.5 5.1 0.0 2.1 26.0 30.6 57.1 3.3 2.4 27.6 8.2 35.2 34.3 2.6 6.8 34.1 14.2 5.6 28.1 9.9 5.2 2.0 1.3 20.2 59.7 8.2 10.3 8.4 84.9 20.8 3.1 1.3 13.1 8.3 9.2 0.6 12.2 7.4 8.2 34.6 5.2 9.4 28.7 21.0 RIMS4 "C20orf190, dJ781B1.3" ENSG00000101098 "Regulating synaptic membrane exocytosis 4" Q9H426 20 44751808-44810546 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.9" "Cell type enhanced" "Detected in some" "Granulosa cells: 110.3;Horizontal cells: 38.7;Inhibitory neurons: 14.4;Sertoli cells: 26.3" "Cancer enhanced" "Detected in many" "breast cancer: 6.6;glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 19.3;MCF7: 13.4;SCLC-21H: 39.9;SH-SY5Y: 20.4;SiHa: 14.0;U-2 OS: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060928 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA060928: AB_2684387" "unprognostic (1.54e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" "unprognostic (9.46e-2)" "unprognostic (2.97e-1)" "unprognostic (1.90e-2)" "unprognostic (4.63e-3)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (4.21e-3)" "unprognostic (1.70e-1)" "unprognostic (8.60e-3)" "unprognostic (3.37e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" 0.4 1.1 17.6 0.2 22.8 0.0 1.1 6.9 35.9 7.2 0.0 0.6 0.1 1.9 0.4 0.5 8.1 0.6 0.6 22.5 12.1 0.1 0.0 0.9 0.1 15.5 9.2 6.1 0.0 0.0 12.0 0.0 10.6 2.5 0.5 2.9 1.1 0.9 1.0 0.4 0.4 2.6 7.7 0.0 1.8 10.5 10.9 0.2 5.0 1.6 0.4 0.1 1.5 20.1 0.0 0.5 0.5 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.9 0.1 2.0 0.0 19.3 0.2 0.0 0.0 8.2 0.0 0.8 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 13.4 0.1 0.0 3.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 39.9 20.4 14.0 0.0 0.2 0.5 6.1 0.7 0.0 0.0 9.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 22.8 6.9 35.9 22.5 12.1 15.5 9.2 10.6 7.7 10.9 20.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 7.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.1 0.1 1.8 0.0 11.3 0.0 0.0 0.4 0.0 0.4 0.0 110.3 0.0 0.0 0.1 38.7 14.4 0.8 0.0 0.0 0.0 2.9 7.2 0.2 0.0 0.0 0.0 1.0 0.0 2.0 0.6 0.1 0.1 13.2 0.0 0.0 0.0 0.0 0.0 1.4 26.3 0.2 1.2 1.2 5.7 0.0 0.1 0.0 0.0 0.5 0.5 0.0 RIPOR1 "FAM65A, FLJ13725" ENSG00000039523 "RHO family interacting cell polarization regulator 1" Q6ZS17 16 67518418-67546788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Endothelial cells: 23.6;Hofbauer cells: 30.0;Pancreatic endocrine cells: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 11.2;eosinophil: 9.3;intermediate monocyte: 15.6;memory B-cell: 15.8;myeloid DC: 10.2;naive B-cell: 9.4;neutrophil: 6.6;non-classical monocyte: 15.1;plasmacytoid DC: 14.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005923 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Cytosol" "HPA005923: AB_1078809" "unprognostic (7.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.56e-3)" "unprognostic (3.71e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.10e-2)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.38e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.82e-8)" "unprognostic (8.51e-2)" "unprognostic (3.52e-2)" "unprognostic (1.19e-1)" "unprognostic (7.46e-2)" 44.4 28.1 27.6 23.4 30.6 27.2 37.7 26.4 38.6 39.9 7.5 36.0 8.8 45.2 6.0 18.5 36.2 21.5 53.6 33.6 16.3 67.6 16.7 55.8 20.8 26.6 17.1 33.2 30.1 20.6 26.5 29.8 25.4 30.6 7.4 43.8 22.8 20.2 34.9 21.4 32.7 25.2 12.3 61.2 25.9 18.6 21.5 10.8 36.4 22.3 17.5 37.1 30.4 18.6 44.0 36.6 16.1 25.3 40.0 35.7 35.7 45.7 44.9 51.6 43.0 75.7 31.5 6.0 62.4 78.8 26.0 24.4 32.7 41.3 33.2 19.3 17.0 57.9 53.6 17.4 44.7 4.6 28.0 35.5 18.8 69.7 47.1 36.8 55.2 10.2 6.5 6.4 38.7 47.7 13.8 14.4 4.4 8.5 29.1 46.8 29.0 31.2 39.0 22.1 12.1 31.9 85.1 13.8 28.6 15.9 30.2 10.7 96.8 58.3 34.2 49.8 32.2 9.0 6.8 17.8 38.8 11.1 31.7 0.1 11.2 9.3 1.2 15.6 1.8 15.8 1.0 0.5 10.2 9.4 0.7 0.7 6.6 1.7 15.1 14.4 0.8 6.0 27.6 30.6 26.4 38.6 33.6 16.3 26.6 17.1 25.4 12.3 21.5 18.6 49.2 16.0 16.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 12.1 8.8 0.0 0.0 1.8 7.3 0.0 0.8 3.7 0.0 0.0 15.8 0.0 9.3 17.9 23.6 0.0 0.0 0.0 12.5 1.3 6.9 0.0 18.5 10.1 7.9 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 37.0 0.0 0.0 2.3 0.0 0.0 5.8 2.2 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 2.1 2.3 16.6 0.0 0.0 RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299864-5304716 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.2" "Cell type enhanced" "Detected in many" "Early spermatids: 13.0;Muller glia cells: 9.6;Spermatocytes: 17.3;Syncytiotrophoblasts: 13.5" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;prostate cancer: 6.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 26 "gdT-cell: 1.4;MAIT T-cell: 4.2;memory B-cell: 1.9;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 3.0;NK-cell: 3.5;T-reg: 1.3" "Group enriched" "Detected in many" 33 "B-cells: 1.9;NK-cells: 3.5;T-cells: 4.2" "Cell line enhanced" "Detected in some" "Daudi: 5.6;HEL: 21.9;T-47d: 6.1;U-266/84: 10.2" "Secreted to blood" NA NA 24400 10000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-3)" "unprognostic (1.26e-1)" "unprognostic (2.09e-3)" "unprognostic (2.84e-1)" "unprognostic (2.03e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (2.50e-3)" "unprognostic (9.18e-2)" "unprognostic (1.74e-6)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-4)" 0.4 0.0 0.4 1.4 0.5 0.3 2.3 0.6 0.7 0.4 0.5 0.5 0.0 0.5 0.3 0.3 5.2 0.2 0.5 0.4 0.5 1.9 0.0 0.7 2.8 0.6 0.5 0.1 0.5 4.2 2.9 0.6 0.6 3.9 0.4 2.9 0.3 0.6 0.0 0.4 0.5 0.2 0.5 0.9 0.5 2.8 0.5 2.7 0.8 0.2 2.3 0.2 0.1 0.5 3.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.0 0.3 1.6 5.6 0.4 0.0 0.0 0.9 0.0 2.8 0.7 4.4 2.0 21.9 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.5 0.0 0.0 0.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.6 2.7 3.0 0.0 0.6 0.1 0.2 6.1 0.1 0.2 0.0 0.5 0.0 0.1 1.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.2 1.9 2.8 2.3 0.0 1.4 4.0 3.0 0.0 3.5 0.0 0.0 1.3 0.8 0.4 0.5 0.6 0.7 0.4 0.5 0.6 0.5 0.6 0.5 0.5 0.5 0.8 3.2 0.6 0.3 2.6 0.5 2.3 1.5 1.2 1.5 3.8 3.0 1.9 1.5 1.2 1.8 0.0 6.3 1.3 0.1 7.9 2.8 13.0 3.3 0.3 0.8 3.6 1.7 0.4 1.5 2.3 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.6 3.3 0.9 1.7 2.0 0.0 0.0 5.3 0.6 0.1 0.0 1.0 0.8 9.6 4.1 0.0 0.9 0.8 0.2 0.4 0.5 1.0 0.1 1.4 5.0 1.7 0.0 0.6 0.4 17.3 5.1 1.4 1.3 13.5 3.4 0.0 1.5 0.5 RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 42000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Cytokinetic bridge" "HPA009975: AB_1078811, HPA074840: " "unprognostic (2.54e-2)" "unprognostic (3.53e-1)" "unprognostic (2.35e-2)" "unprognostic (3.97e-3)" "unprognostic (1.50e-1)" "unprognostic (2.50e-3)" "unprognostic (2.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.94e-3)" "prognostic favorable (6.70e-8)" "unprognostic (1.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.79e-3)" "unprognostic (2.04e-3)" 30.1 22.7 37.2 16.2 40.2 24.1 26.7 38.4 48.6 18.0 31.2 18.1 43.8 15.9 5.4 22.6 18.8 16.7 16.4 36.3 36.1 18.4 37.0 36.5 15.6 40.2 38.6 17.2 27.2 36.3 10.9 19.4 36.0 17.2 9.0 6.7 33.3 15.4 20.7 21.1 51.7 11.2 37.7 13.0 21.5 13.8 42.9 15.0 19.9 14.1 8.4 20.3 17.6 41.2 19.7 17.7 21.0 35.9 19.2 17.2 36.3 50.2 19.8 34.9 25.6 63.7 21.7 16.7 65.0 27.0 26.0 66.3 26.9 37.3 3.7 44.2 33.1 53.6 51.4 31.6 62.9 36.4 41.1 30.9 34.0 25.2 23.9 16.3 24.8 32.6 57.4 44.9 15.1 40.0 27.7 23.6 16.7 52.7 34.6 42.6 25.1 38.9 28.8 32.7 49.8 18.1 39.9 53.4 19.5 8.2 41.6 39.1 37.3 37.8 27.0 51.1 42.5 34.0 42.7 26.7 26.8 38.2 42.2 4.0 13.2 5.5 28.2 17.8 25.0 16.0 20.6 26.0 14.4 13.7 15.9 17.3 2.1 65.1 22.3 54.2 20.3 26.6 37.2 40.2 38.4 48.6 36.3 36.1 40.2 38.6 36.0 37.7 42.9 41.2 20.1 32.1 28.1 18.6 11.0 15.7 16.4 26.9 15.9 20.0 21.0 13.6 8.1 15.7 27.8 18.4 4.2 44.4 22.4 17.2 1.9 27.7 2.8 20.7 17.8 18.1 4.9 42.7 23.5 22.0 28.5 17.8 13.7 22.0 19.0 8.6 17.5 36.4 110.7 18.5 18.2 12.3 26.4 14.7 10.4 3.4 16.8 21.0 19.6 8.4 11.7 21.6 43.3 16.1 21.8 21.8 16.7 14.3 18.0 17.3 77.6 14.5 29.3 17.3 6.6 22.2 16.0 40.4 40.4 21.9 11.9 62.8 18.3 16.7 21.4 23.1 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNF157 KIAA1917 ENSG00000141576 "Ring finger protein 157" Q96PX1 17 76142465-76240493 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 86.9;retina: 59.0;skeletal muscle: 73.9;testis: 31.4;tongue: 43.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 114.1;Cone photoreceptor cells: 189.7;Excitatory neurons: 64.6;Horizontal cells: 180.0;Inhibitory neurons: 92.7;Rod photoreceptor cells: 70.9" "Cancer enhanced" "Detected in many" "glioma: 11.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.2;T-cells: 5.8" "Cell line enhanced" "Detected in many" "HDLM-2: 100.9;U-266/70: 50.6;U-266/84: 45.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021854, HPA021991, HPA023922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" Vesicles "HPA021854: AB_10600307, HPA021991: AB_10601112, HPA023922: AB_10602202" "unprognostic (4.21e-1)" "unprognostic (4.62e-2)" "unprognostic (1.55e-2)" "unprognostic (2.63e-3)" "unprognostic (4.93e-2)" "unprognostic (5.06e-2)" "unprognostic (2.07e-3)" "unprognostic (4.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (1.04e-3)" "unprognostic (4.02e-1)" "unprognostic (8.26e-2)" "unprognostic (8.69e-3)" "unprognostic (2.28e-1)" "unprognostic (2.75e-2)" "unprognostic (1.38e-1)" 13.6 3.3 36.4 3.7 39.1 2.2 4.9 34.1 86.9 1.4 9.8 9.8 9.6 1.4 3.4 1.0 1.8 1.3 6.4 56.9 34.5 5.8 2.5 1.4 5.2 59.7 41.9 1.2 3.4 14.6 6.3 1.6 61.1 1.9 7.0 59.0 1.9 1.5 73.9 1.0 10.3 1.8 34.1 3.5 3.9 31.4 51.5 2.8 3.4 43.7 2.7 3.0 1.0 58.1 0.2 7.1 29.3 10.7 8.8 4.4 13.4 0.3 8.9 1.9 1.3 3.3 3.1 0.0 4.2 0.5 6.9 0.2 26.0 0.1 1.6 100.9 8.9 0.0 2.9 4.7 1.7 1.4 10.9 2.4 0.1 3.7 0.1 1.5 0.2 4.7 16.0 0.3 3.6 8.0 4.4 0.8 4.8 5.5 21.1 0.0 0.3 0.1 3.4 3.2 5.1 24.0 5.3 0.1 11.5 6.5 0.7 5.1 0.2 1.9 2.3 14.4 9.6 50.6 45.5 0.1 0.8 0.1 15.1 2.2 0.2 0.3 1.6 0.1 3.4 0.2 3.4 2.7 0.1 0.4 5.8 3.9 1.2 0.7 0.2 0.3 1.3 1.0 36.4 39.1 34.1 86.9 56.9 34.5 59.7 41.9 61.1 34.1 51.5 58.1 2.8 3.2 3.3 33.3 1.5 2.0 0.8 0.2 0.6 114.1 0.8 0.9 9.0 11.5 1.3 1.8 189.7 0.6 5.0 5.3 0.0 1.9 27.8 0.6 3.7 4.4 2.4 5.5 64.6 1.1 0.4 3.1 0.0 1.5 0.0 0.9 0.7 4.3 0.4 180.0 92.7 7.4 0.0 0.8 6.0 29.1 11.5 1.1 1.8 3.7 1.4 35.9 8.2 62.8 35.0 0.1 3.4 13.9 2.1 0.9 19.3 9.1 0.7 70.9 0.0 2.9 1.3 22.7 25.0 0.0 2.3 0.3 15.5 1.3 18.2 1.5 RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.2;lymphoid tissue: 101.6" "Cell type enhanced" "Detected in all" "dendritic cells: 132.3;NK-cells: 111.2;T-cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: AB_10796682" "unprognostic (3.01e-2)" "unprognostic (6.98e-3)" "unprognostic (3.96e-2)" "unprognostic (5.36e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (6.52e-2)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (2.38e-2)" "prognostic favorable (1.04e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.54e-1)" "unprognostic (3.91e-2)" "unprognostic (1.28e-1)" "unprognostic (2.69e-2)" 22.7 18.4 16.1 28.8 16.2 91.2 16.0 14.4 24.5 18.3 13.9 18.3 14.1 16.6 3.2 11.8 20.0 14.0 21.3 15.5 15.0 20.7 23.4 48.3 40.4 19.4 16.8 17.8 19.5 5.4 17.6 8.2 17.6 19.7 4.9 3.4 14.8 5.8 21.3 11.8 37.2 6.3 16.9 101.6 17.8 12.8 20.9 18.0 18.8 8.2 21.1 18.1 14.4 20.0 10.3 15.9 12.5 18.4 5.8 5.0 23.3 10.3 6.5 11.8 5.3 11.1 6.4 12.4 13.0 6.0 6.8 11.1 7.2 6.8 4.7 6.4 21.7 16.7 12.4 18.7 15.9 16.7 20.4 6.0 6.4 9.4 8.2 6.9 12.4 20.6 28.6 8.8 5.0 20.3 38.9 108.0 20.3 4.4 21.5 36.3 7.8 32.2 5.3 4.5 11.8 12.3 23.9 4.8 12.1 5.9 13.4 53.3 18.6 8.7 13.4 13.5 12.5 19.9 13.5 31.6 7.8 62.8 12.4 7.0 25.6 61.3 31.6 19.1 27.7 4.2 19.3 27.6 23.8 3.9 15.7 22.9 40.4 11.3 22.7 14.8 21.8 21.6 16.1 16.2 14.4 24.5 15.5 15.0 19.4 16.8 17.6 16.9 20.9 20.0 15.2 9.6 3.6 7.8 23.5 4.8 4.6 2.4 6.2 10.1 6.0 7.1 2.8 4.3 3.1 7.3 6.2 8.8 132.3 2.3 9.8 6.5 1.4 5.2 7.4 11.0 4.9 13.7 6.5 9.2 9.6 8.8 8.2 4.9 21.0 12.3 8.6 4.8 38.8 8.4 4.8 3.1 2.0 46.7 32.4 2.5 9.3 52.4 10.6 15.0 41.5 11.7 111.2 3.5 4.5 5.5 1.0 7.9 55.1 4.5 1.8 7.0 4.7 9.6 6.6 8.9 10.0 9.1 9.9 4.8 5.8 3.7 73.1 12.2 3.7 1.9 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980310 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.7;choroid plexus: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 85.2" "Cancer enhanced" "Detected in many" "glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 81.3;RPTEC TERT1: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.1 0.1 12.2 0.1 13.3 8.4 0.6 22.5 17.7 0.8 12.7 0.2 0.2 0.6 1.1 0.3 1.2 0.2 0.3 17.6 12.2 1.1 0.0 3.3 0.2 16.9 17.7 0.3 1.7 5.8 1.8 1.3 16.5 0.4 0.1 8.8 1.3 2.1 0.2 0.4 0.3 0.3 14.2 0.2 0.2 3.7 24.7 1.5 1.3 0.1 0.0 0.3 0.4 12.2 0.2 6.5 12.0 0.0 4.1 5.0 0.7 6.3 8.6 17.0 16.4 0.3 0.1 0.0 0.1 6.8 18.5 0.0 14.3 0.1 30.9 0.0 4.7 0.4 81.3 0.0 0.0 0.1 0.0 2.8 0.0 26.3 0.2 19.5 0.3 3.5 0.5 0.0 11.9 0.2 0.1 2.2 6.9 0.1 23.9 3.8 2.9 1.0 67.3 0.0 14.2 13.7 0.6 0.0 24.8 4.4 0.0 2.4 6.5 20.7 4.4 0.2 14.3 0.0 0.0 0.0 14.1 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 13.3 22.5 17.7 17.6 12.2 16.9 17.7 16.5 14.2 24.7 12.2 0.2 0.0 0.0 85.2 0.1 0.3 0.1 0.0 0.0 19.3 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 0.4 0.1 0.2 0.0 9.7 8.6 0.0 0.1 0.4 0.0 0.1 0.0 5.4 0.0 0.1 0.1 15.2 1.5 0.1 0.0 0.0 0.3 1.4 0.3 0.0 0.0 5.6 0.0 14.7 0.0 2.5 0.4 0.1 0.0 0.0 0.0 0.1 0.0 1.1 0.1 1.3 6.6 0.0 1.3 5.7 3.2 0.0 0.0 0.3 0.3 0.0 0.1 0.1 RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202179-56221933 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: AB_1856370" "unprognostic (1.14e-2)" "unprognostic (6.30e-2)" "unprognostic (4.04e-2)" "unprognostic (6.86e-2)" "unprognostic (9.59e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (6.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" 32.2 24.6 22.5 18.0 23.3 19.6 21.4 15.7 23.8 21.2 13.0 23.8 12.4 22.3 13.2 23.1 24.3 25.5 32.7 24.6 24.8 19.7 15.1 23.8 23.4 16.8 19.1 22.9 23.0 27.4 22.8 21.3 21.2 33.9 19.0 23.8 15.0 20.7 34.0 15.0 16.1 28.5 15.3 20.6 17.0 15.9 23.5 26.5 28.6 40.8 25.1 28.2 17.0 19.2 21.6 32.6 34.7 55.2 71.0 51.3 25.8 70.8 69.5 62.2 50.2 40.0 27.6 41.6 36.7 60.2 20.6 24.3 47.4 34.1 44.9 43.8 25.7 55.8 22.3 23.2 148.3 61.6 58.3 66.0 78.6 52.0 91.0 81.7 61.3 34.5 40.4 41.3 35.1 34.9 35.6 27.6 41.9 21.6 37.8 38.2 24.9 25.3 33.3 31.3 62.9 38.1 61.9 35.0 55.4 34.3 49.2 71.3 37.3 31.3 32.9 40.6 27.8 29.6 36.6 37.5 37.2 36.4 38.0 59.1 27.2 99.9 27.6 26.7 24.9 50.3 23.0 24.3 30.6 55.1 23.4 24.0 36.2 33.1 28.3 23.7 29.4 31.0 22.5 23.3 15.7 23.8 24.6 24.8 16.8 19.1 21.2 15.3 23.5 19.2 18.9 44.8 22.6 11.1 42.2 12.0 19.9 8.6 19.9 30.7 22.2 21.1 24.6 24.3 18.8 16.5 22.9 15.2 17.0 10.2 17.6 15.3 92.8 13.9 14.2 20.7 20.4 11.1 15.0 21.3 18.5 22.7 9.7 14.2 25.9 16.8 30.0 16.7 19.3 28.6 15.7 13.9 8.2 34.9 22.7 58.0 23.0 25.0 7.2 9.4 33.5 26.2 15.5 14.6 12.3 20.8 20.3 25.9 14.6 33.5 12.3 19.6 18.0 18.3 26.3 23.2 27.4 10.4 14.2 14.4 16.6 16.8 16.6 17.1 14.3 23.1 RNPEPL1 ENSG00000142327 "Arginyl aminopeptidase like 1" Q9HAU8 2 240565804-240581372 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036772, HPA036773" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA036772: AB_10670848, HPA036773: " "unprognostic (3.92e-2)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.39e-1)" "unprognostic (5.24e-3)" "prognostic favorable (7.43e-4)" "prognostic unfavorable (5.06e-4)" "unprognostic (3.72e-3)" "unprognostic (9.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (5.31e-2)" "unprognostic (9.86e-2)" 40.3 31.4 29.1 14.1 29.6 21.7 32.0 29.0 38.7 15.6 27.0 39.6 20.2 16.8 5.6 52.4 17.0 12.1 79.4 27.9 27.8 42.7 50.6 35.9 23.8 31.5 30.0 12.0 64.2 10.9 9.1 10.6 30.3 34.7 9.5 0.8 28.9 13.1 63.7 35.3 39.8 9.4 31.0 56.4 48.4 9.9 31.4 15.9 19.2 17.1 12.1 34.1 23.2 31.1 13.7 22.4 4.9 13.2 17.6 18.1 16.6 8.6 21.1 9.5 11.6 6.3 39.3 3.9 4.3 21.8 13.3 14.6 5.5 16.1 0.9 23.9 7.7 9.0 7.3 37.2 44.1 5.9 15.5 21.6 25.5 4.9 9.6 15.1 32.8 15.2 6.8 25.7 6.5 19.3 7.5 22.4 6.5 26.5 9.0 15.5 7.4 33.3 39.3 18.5 4.6 9.8 5.8 19.7 39.9 5.6 13.9 26.8 22.7 10.2 10.4 14.4 10.0 24.1 3.9 4.8 20.9 16.6 15.7 9.2 11.2 30.5 14.8 9.9 12.7 8.2 11.3 13.4 8.2 8.7 6.4 9.5 20.0 10.7 10.1 9.5 14.7 7.9 29.1 29.6 29.0 38.7 27.9 27.8 31.5 30.0 30.3 31.0 31.4 31.1 27.9 22.4 25.7 10.4 27.8 7.8 15.0 8.4 2.8 6.4 18.8 9.1 35.6 24.3 12.9 12.9 0.0 7.1 80.4 138.9 17.6 24.6 3.1 12.1 11.0 22.7 26.4 22.3 9.5 49.6 6.8 12.3 104.5 27.4 34.2 31.8 30.0 42.2 43.8 3.3 8.6 58.7 8.2 74.3 21.0 5.9 8.7 47.1 23.2 9.4 52.0 15.9 79.3 5.5 10.3 65.0 70.0 13.5 20.5 20.2 77.1 35.6 7.2 6.9 13.1 14.8 16.4 1.3 8.2 13.0 9.2 5.1 47.9 17.4 60.5 23.0 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 280.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 710000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 36.4 9.3 6.7 13.5 16.3 6.8 22.3 19.1 14.3 18.7 0.8 22.6 16.7 22.0 10.3 16.2 13.6 15.6 17.0 12.1 3.5 14.5 16.5 16.9 10.1 1.7 4.4 19.0 11.7 12.8 5.9 24.9 1.4 17.4 26.2 13.5 14.6 18.1 30.4 8.5 19.2 27.9 2.0 16.4 14.1 7.8 6.4 8.4 13.9 28.9 8.8 21.1 11.0 10.4 17.5 41.7 33.8 33.2 59.7 41.6 21.6 40.4 37.7 25.8 27.1 39.8 37.2 21.9 23.4 64.5 31.3 18.9 24.7 23.4 40.6 31.2 14.7 43.8 70.6 79.7 21.4 24.7 12.1 32.6 14.6 31.9 22.6 21.0 42.0 11.9 38.6 8.6 38.8 14.8 18.2 12.7 18.8 36.9 25.3 21.7 74.2 7.0 14.0 48.8 15.9 16.9 79.6 27.4 27.4 25.5 11.3 13.6 57.3 52.9 38.2 21.2 36.0 6.8 8.9 18.8 22.8 28.2 75.4 0.9 0.4 0.4 0.6 0.4 0.7 0.3 0.4 0.4 0.3 0.5 0.4 0.4 0.6 0.8 0.4 0.6 0.4 0.2 6.7 16.3 19.1 14.3 12.1 3.5 1.7 4.4 1.4 2.0 6.4 10.4 114.5 115.4 79.1 81.3 16.0 39.9 43.0 15.3 21.1 35.7 33.5 41.1 107.0 37.1 53.1 22.0 58.4 26.3 20.4 97.7 1.9 27.1 11.0 53.6 141.2 90.3 21.2 22.5 280.4 39.5 19.1 64.0 18.3 55.3 29.0 36.9 56.0 43.1 19.6 80.8 158.1 92.2 10.2 20.3 27.0 4.9 43.8 30.4 23.2 107.7 20.6 38.4 15.5 99.0 66.9 39.1 43.6 78.6 16.2 53.5 45.3 15.7 32.7 48.5 131.5 70.0 118.5 30.3 24.6 19.9 27.8 31.5 18.5 34.2 54.8 40.7 RPS6KA2 "HU-2, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 399.6;Excitatory neurons: 204.1;Horizontal cells: 287.7;Inhibitory neurons: 552.3;Oligodendrocyte precursor cells: 244.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 26.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "eosinophil: 22.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.4" "Cell line enhanced" "Detected in many" "ASC diff: 214.5;ASC TERT1: 156.1;HHSteC: 158.5;HSkMC: 141.4;hTERT-HME1: 173.0;hTERT-RPE1: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: AB_2679203, HPA054237: AB_2682425" "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favorable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 34.2 9.0 40.3 8.0 41.0 10.5 27.8 35.0 35.2 18.1 8.6 16.6 6.1 26.0 7.1 20.1 18.7 18.2 61.8 37.8 42.1 13.6 6.6 45.1 7.5 48.3 41.7 29.2 19.4 49.6 27.2 17.9 42.0 14.9 10.3 28.9 14.7 14.2 24.1 16.4 16.5 22.7 35.3 26.0 21.4 7.7 47.3 5.9 36.3 30.5 7.3 24.5 14.9 49.3 9.1 0.0 17.9 26.0 214.5 156.1 0.4 19.3 37.4 10.6 14.6 0.0 5.8 1.1 6.2 68.2 8.4 8.2 9.4 41.8 9.4 4.2 2.3 0.1 40.2 0.4 158.5 0.6 7.2 141.4 29.4 56.6 173.0 316.2 58.0 19.2 0.2 0.2 43.6 1.9 0.8 2.1 4.5 9.1 10.5 3.0 9.2 27.3 11.1 10.1 9.8 68.8 6.7 17.9 24.8 4.4 0.5 14.3 21.7 37.3 3.7 103.8 5.6 5.2 8.4 2.6 24.8 1.2 36.0 0.2 0.6 22.4 0.6 0.8 0.3 0.3 0.6 0.3 0.8 0.5 0.7 0.3 0.5 4.4 2.2 4.7 0.5 0.4 40.3 41.0 35.0 35.2 37.8 42.1 48.3 41.7 42.0 35.3 47.3 49.3 60.9 22.4 46.2 399.6 2.7 4.7 5.4 4.6 3.4 37.1 7.1 5.0 60.0 15.7 11.6 36.8 8.4 0.2 8.0 1.9 11.7 15.2 14.8 20.6 4.6 58.2 5.4 0.0 204.1 24.0 0.3 16.3 16.8 20.3 2.5 10.5 45.3 11.9 7.2 287.7 552.3 5.3 2.0 6.0 6.7 69.3 5.3 8.0 19.6 144.3 3.5 10.1 1.0 244.8 97.7 26.8 1.7 4.5 2.4 9.9 0.3 7.0 9.4 17.1 13.1 10.0 14.5 3.5 2.3 1.2 3.4 0.3 2.0 9.5 1.4 6.6 RRAGC "FLJ13311, GTR2" ENSG00000116954 "Ras related GTP binding C" Q9HB90 1 38838198-38859772 "Disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018247, HPA055489" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Vesicles" "HPA018247: AB_1856475, HPA055489: AB_2682832" "unprognostic (2.04e-2)" "unprognostic (1.58e-1)" "unprognostic (2.63e-2)" "unprognostic (1.41e-2)" "unprognostic (3.40e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (9.97e-9)" "unprognostic (2.14e-1)" "unprognostic (3.61e-2)" "unprognostic (4.98e-2)" "unprognostic (2.23e-2)" "unprognostic (1.71e-1)" "unprognostic (5.13e-2)" "unprognostic (6.38e-2)" "unprognostic (2.69e-1)" "unprognostic (2.77e-1)" "unprognostic (3.82e-2)" 37.0 16.9 18.0 16.6 19.2 30.2 25.2 20.0 19.4 17.1 16.4 21.5 18.7 16.1 14.0 24.9 13.9 17.7 21.6 17.6 20.4 24.5 18.5 19.3 20.5 20.4 21.3 21.6 14.2 24.0 10.0 28.5 21.3 14.9 17.0 16.1 14.2 16.9 17.4 29.8 16.2 21.9 19.5 17.3 15.1 17.5 19.8 18.8 16.7 18.9 21.8 19.0 18.1 21.3 37.0 16.6 21.3 23.3 110.7 74.6 33.0 33.7 68.6 44.8 47.2 12.7 23.9 23.0 18.9 52.6 71.8 21.7 40.1 22.2 36.8 37.6 28.3 22.1 19.2 14.7 135.6 26.0 23.9 66.7 55.2 48.0 61.9 35.4 47.5 24.5 22.9 44.9 65.7 10.2 19.0 14.7 27.2 15.9 28.0 18.1 37.6 15.6 31.6 42.5 11.1 16.5 27.0 20.0 73.2 47.5 18.3 19.5 42.5 54.3 22.4 60.0 29.2 35.0 60.5 26.8 50.5 29.1 28.8 0.5 2.4 5.5 1.7 2.3 2.9 3.3 2.6 2.2 2.3 3.6 2.2 2.1 5.9 1.7 1.8 8.4 2.5 1.6 18.0 19.2 20.0 19.4 17.6 20.4 20.4 21.3 21.3 19.5 19.8 21.3 31.2 32.1 28.0 6.5 42.1 111.9 47.1 19.2 40.9 20.0 31.0 25.0 22.2 24.3 16.1 12.9 12.5 84.9 38.4 30.3 11.7 55.7 56.3 32.0 26.6 34.3 14.4 24.0 7.4 48.1 57.7 39.4 12.2 42.9 16.5 16.9 35.7 14.2 72.1 38.7 8.3 10.3 20.3 34.4 65.0 49.8 30.7 49.2 53.4 9.4 63.3 43.4 10.3 7.5 15.8 47.0 14.0 37.2 20.1 47.3 21.5 30.4 15.0 22.8 19.7 28.1 37.5 24.7 28.5 46.1 140.5 224.1 23.3 18.6 12.2 51.1 RRNAD1 "C1orf66, CGI-41, METTL25B" ENSG00000143303 "Ribosomal RNA adenine dimethylase domain containing 1" Q96FB5 1 156728442-156736960 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047426 Approved Approved Nucleoli,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoli Cytosol "HPA047426: AB_2680041" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (2.00e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-1)" "unprognostic (2.89e-3)" "unprognostic (2.24e-1)" "unprognostic (2.76e-1)" "unprognostic (2.14e-1)" "unprognostic (3.35e-2)" "unprognostic (1.49e-1)" "unprognostic (5.03e-3)" 17.1 21.3 16.5 14.1 20.0 11.9 21.9 18.8 18.1 22.4 20.6 21.0 27.4 22.0 26.0 21.8 28.2 17.7 14.9 15.9 17.1 18.6 28.4 17.7 19.5 20.7 18.7 26.5 27.6 25.4 20.5 14.8 18.8 25.0 17.4 17.9 27.2 22.9 30.2 29.1 24.0 14.8 18.2 20.4 23.8 24.4 18.6 14.2 29.4 22.8 17.0 22.5 20.9 22.9 14.6 28.3 20.6 20.3 54.2 24.7 31.3 10.8 32.8 18.3 13.7 15.3 65.7 24.8 31.6 17.1 25.7 60.7 28.9 25.4 7.3 49.5 24.3 15.0 27.5 11.6 34.1 22.4 39.2 38.4 47.5 18.3 34.3 21.5 15.5 21.8 36.3 54.1 9.9 35.3 11.6 26.0 23.9 63.2 8.7 18.7 13.6 58.1 21.8 15.6 26.7 38.2 19.2 38.7 24.0 31.2 51.5 47.2 15.0 11.3 13.8 17.7 14.7 62.7 67.7 31.8 12.7 24.9 13.9 4.1 1.8 2.7 3.5 1.3 3.6 1.7 3.3 2.5 3.2 2.3 2.7 3.0 4.0 4.0 2.3 1.2 5.1 1.7 16.5 20.0 18.8 18.1 15.9 17.1 20.7 18.7 18.8 18.2 18.6 22.9 9.5 6.4 15.1 11.4 15.8 10.1 21.5 13.5 22.2 11.2 20.0 19.9 7.1 31.5 13.9 3.7 12.5 24.9 8.9 16.4 9.8 12.7 60.2 12.3 6.4 9.7 9.6 14.3 4.6 13.1 17.2 11.2 18.3 10.9 5.1 8.7 12.5 19.5 10.9 8.4 6.3 16.9 14.2 11.1 4.9 14.7 11.1 9.6 8.8 4.7 10.1 20.5 5.2 5.5 15.9 9.3 12.8 9.4 14.8 21.4 36.5 12.8 13.9 13.6 13.1 9.6 9.6 20.6 23.2 18.9 11.5 32.4 8.1 8.2 16.2 18.0 RTF2 "C20orf43, CDAO5, HSPC164, RTFDC1" ENSG00000022277 "Replication termination factor 2" Q9BY42 20 56468585-56519449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 162.8;Distal tubular cells: 156.5;Proximal tubular cells: 149.9;Syncytiotrophoblasts: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053986 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA053986: AB_2682333" "unprognostic (1.65e-1)" "unprognostic (1.94e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (3.54e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (8.90e-2)" "unprognostic (4.02e-3)" "unprognostic (1.16e-1)" "unprognostic (8.98e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "unprognostic (4.58e-1)" "unprognostic (8.48e-3)" 73.8 72.7 101.4 65.9 113.3 128.5 65.7 117.4 106.7 66.2 88.3 79.2 60.5 70.6 48.9 64.2 64.8 49.2 85.9 97.2 106.7 68.7 63.8 58.1 70.7 113.7 109.6 71.1 59.3 63.0 67.8 55.4 115.0 58.2 54.2 61.3 51.2 62.2 181.4 69.6 60.8 65.4 111.1 67.8 59.3 57.0 108.4 79.2 60.6 111.1 76.2 73.8 57.5 123.5 132.8 93.3 91.1 91.3 111.1 97.9 85.9 198.5 148.1 280.0 158.5 192.6 125.2 110.4 232.0 161.5 139.7 144.9 92.4 153.8 190.7 52.6 72.9 138.9 97.4 150.8 127.9 201.3 186.6 88.1 156.5 126.0 106.9 119.7 121.3 118.1 109.6 114.3 139.1 253.9 171.6 173.0 68.8 185.2 175.9 116.3 247.2 149.5 119.1 86.1 95.1 103.1 208.2 355.0 199.0 66.7 165.0 191.7 131.5 242.2 156.0 133.0 165.1 94.6 116.1 156.9 190.7 134.7 135.1 309.4 205.4 562.3 125.6 192.8 106.2 115.7 106.4 122.5 223.6 134.0 119.7 110.6 580.4 197.4 200.5 189.6 152.2 254.1 101.4 113.3 117.4 106.7 97.2 106.7 113.7 109.6 115.0 111.1 108.4 123.5 87.2 51.3 61.2 0.0 20.9 0.0 0.0 0.0 0.0 0.0 54.1 56.9 0.0 0.0 34.0 66.2 0.0 162.8 50.9 0.0 156.5 104.5 0.0 47.8 51.2 38.8 0.0 0.0 0.0 96.3 109.5 37.3 0.0 47.7 90.8 57.9 0.0 0.0 110.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.8 0.0 0.0 92.0 0.0 0.0 0.0 0.0 101.9 0.0 0.0 5.3 0.0 0.0 149.9 34.2 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 182.9 26.4 89.8 0.0 0.0 RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 514.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1074.7" "Group enriched" "Detected in all" 6 "granulocytes: 1074.7;monocytes: 400.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA015649: AB_1856498, HPA015650: AB_1856499" "unprognostic (8.11e-3)" "unprognostic (8.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.88e-3)" "unprognostic (1.41e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (5.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.87e-4)" "unprognostic (1.60e-2)" "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-2)" 207.5 81.8 361.4 54.1 412.2 108.5 93.3 338.4 514.5 87.6 190.7 88.1 54.0 62.5 81.2 55.7 88.5 56.3 57.4 428.4 378.9 92.8 87.5 77.8 36.0 404.5 309.1 48.1 91.1 109.9 81.0 62.2 417.2 53.3 79.9 194.4 138.8 76.1 70.2 103.7 65.2 80.1 329.2 51.7 57.0 46.6 334.0 53.7 175.5 43.7 48.5 55.7 54.2 384.0 157.5 113.8 134.0 128.4 242.3 170.9 53.4 139.3 147.5 120.5 128.4 99.6 338.1 184.2 231.7 210.0 115.7 157.2 194.0 68.7 157.5 149.5 103.5 236.5 151.3 70.4 201.1 212.8 182.4 113.5 199.2 146.7 162.3 200.7 165.2 158.9 136.2 290.1 107.4 129.2 113.4 235.2 156.7 127.3 127.3 148.4 93.8 342.9 239.7 87.5 282.7 164.0 226.2 245.3 271.5 95.4 271.1 172.7 155.2 71.3 95.6 251.1 108.4 183.4 169.9 145.6 274.7 173.8 77.2 441.0 400.1 487.7 41.4 187.6 44.8 28.6 41.6 41.3 130.8 19.4 30.1 32.7 1074.7 41.7 240.4 79.0 68.6 323.0 361.4 412.2 338.4 514.5 428.4 378.9 404.5 309.1 417.2 329.2 334.0 384.0 62.8 134.6 67.5 110.7 35.9 144.5 103.5 63.0 101.3 157.7 125.2 59.9 36.1 81.5 91.9 244.6 70.9 68.6 55.6 118.2 29.4 154.4 35.8 96.4 74.3 68.1 99.8 85.8 398.8 117.1 105.6 96.7 60.1 129.2 77.3 71.4 85.6 81.3 143.7 82.4 372.7 83.5 122.1 178.3 110.8 71.2 79.2 151.4 113.8 100.2 178.0 150.3 42.2 200.6 294.8 103.3 82.0 89.9 94.8 79.4 94.5 55.9 156.0 97.6 78.9 53.1 78.6 194.7 133.5 85.9 146.2 86.5 48.8 51.7 96.5 99.8 RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3547.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 95.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1801.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 38: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" 586.2 302.7 376.3 150.9 461.9 115.4 253.1 465.9 534.3 118.0 297.1 186.9 236.2 153.9 176.5 217.9 130.0 196.8 166.0 411.8 431.6 442.5 551.9 211.8 83.6 498.6 456.5 132.0 122.7 236.7 84.0 177.3 524.8 223.9 179.2 640.6 127.1 183.4 996.0 252.9 292.5 246.4 440.8 110.3 124.0 78.6 453.2 87.1 130.7 777.9 88.2 291.2 147.9 591.2 402.9 285.3 273.3 71.7 908.4 845.0 153.2 1301.6 1097.4 393.5 365.7 235.5 371.7 87.1 673.8 889.9 657.7 355.6 181.5 524.4 596.2 248.3 139.4 120.3 159.6 376.6 1801.9 218.1 59.7 638.5 490.8 540.3 1041.9 792.3 751.3 215.6 249.8 195.0 1724.1 117.8 268.3 222.0 245.9 86.8 252.0 118.5 360.3 180.0 924.0 475.9 179.2 211.3 297.7 173.3 378.1 465.1 147.2 165.1 1074.9 764.8 326.1 304.8 756.5 118.0 103.4 56.1 778.7 247.9 630.1 95.8 9.5 27.5 9.2 11.6 7.6 6.8 14.7 8.2 9.2 3.8 24.1 10.2 15.6 41.1 19.0 13.7 37.6 9.9 376.3 461.9 465.9 534.3 411.8 431.6 498.6 456.5 524.8 440.8 453.2 591.2 451.4 176.3 203.4 201.4 102.3 1062.1 1456.6 367.0 225.9 644.6 297.6 260.6 182.0 243.1 251.0 676.8 379.5 529.6 173.6 408.6 291.6 559.7 459.7 316.6 264.6 308.0 222.1 98.2 454.5 323.4 611.9 421.9 98.4 324.7 150.4 161.5 181.3 633.4 669.1 425.7 370.4 280.5 231.9 339.0 578.4 266.6 167.4 371.7 341.5 215.5 396.4 3547.4 137.0 249.3 1334.3 571.2 309.7 226.1 81.6 921.4 897.1 678.3 233.6 540.0 216.9 420.5 324.6 382.7 90.1 247.1 1059.3 362.0 145.5 100.1 238.1 1226.5 RUBCNL "C13orf18, FLJ21562, KIAA0226L, PACER" ENSG00000102445 "Rubicon like autophagy enhancer" Q9H714 13 46334681-46438190 "Predicted intracellular proteins" "Autophagy, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 6.1;B-cells: 20.7;Endometrial stromal cells: 6.7;Hofbauer cells: 16.7;Macrophages: 5.2" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "memory B-cell: 161.2;naive B-cell: 155.8;neutrophil: 124.0;plasmacytoid DC: 106.2" "Group enriched" "Detected in many" 15 "B-cells: 161.2;dendritic cells: 106.2;granulocytes: 124.0" "Group enriched" "Detected in some" 4 "Daudi: 179.1;U-698: 341.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026614 Approved Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA026614: AB_10602693" "unprognostic (3.35e-2)" "unprognostic (2.61e-1)" "unprognostic (1.94e-3)" "prognostic favorable (3.76e-5)" "unprognostic (1.09e-2)" "unprognostic (8.30e-4)" "unprognostic (7.83e-2)" "unprognostic (2.62e-3)" "unprognostic (1.07e-1)" "unprognostic (1.95e-1)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "unprognostic (5.95e-5)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (7.47e-2)" "unprognostic (7.00e-3)" 4.2 1.3 3.7 18.0 3.8 14.8 4.0 3.5 4.1 6.6 2.5 11.9 3.0 3.7 1.2 1.0 3.7 4.0 1.0 3.4 6.8 1.1 2.2 5.2 41.2 6.2 4.8 0.6 0.7 0.3 2.0 4.2 6.1 1.5 16.2 3.9 3.0 2.6 10.1 2.0 13.2 3.6 4.9 20.3 2.2 15.7 6.3 22.9 1.9 1.4 40.6 7.5 1.3 5.9 0.5 0.1 3.6 0.2 0.1 0.2 0.3 0.0 0.2 0.2 0.1 7.5 0.2 179.1 1.8 0.0 0.9 0.2 0.1 0.0 0.1 0.7 0.3 0.2 0.2 0.1 0.0 0.2 0.2 4.7 0.0 0.6 0.9 0.0 0.0 8.2 0.3 0.4 0.0 0.1 1.9 1.4 1.5 0.0 1.4 62.6 0.1 6.1 0.0 0.1 3.4 0.1 0.2 0.3 4.4 10.8 0.2 53.0 0.1 0.2 1.6 0.3 0.4 0.9 37.3 341.2 1.1 0.3 0.2 0.5 4.5 0.1 0.1 8.9 0.1 161.2 0.3 0.1 5.1 155.8 0.1 0.1 124.0 3.5 7.1 106.2 0.2 7.5 3.7 3.8 3.5 4.1 3.4 6.8 6.2 4.8 6.1 4.9 6.3 5.9 0.2 3.2 6.1 0.0 20.7 0.0 0.0 0.0 0.0 0.0 2.9 3.9 0.0 0.0 2.5 0.0 0.0 0.3 0.3 0.0 0.0 1.4 0.0 1.3 6.7 0.4 0.0 0.0 0.0 1.2 0.4 1.1 0.0 2.5 2.5 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.0 0.0 RUFY4 "FLJ46536, ZFYVE31" ENSG00000188282 "RUN and FYVE domain containing 4" Q6ZNE9 2 218034960-218090581 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;lymphoid tissue: 2.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 9.5;Langerhans cells: 4.0;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "Karpas-707: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA037980 Uncertain NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA037980: AB_10672501" "unprognostic (1.27e-3)" "unprognostic (4.60e-3)" "unprognostic (9.39e-3)" "unprognostic (6.79e-2)" "unprognostic (5.92e-2)" "unprognostic (6.57e-3)" "unprognostic (1.16e-1)" "unprognostic (2.42e-2)" "unprognostic (1.31e-3)" "unprognostic (1.50e-1)" "unprognostic (6.09e-2)" "unprognostic (1.55e-1)" "unprognostic (2.41e-14)" "unprognostic (1.36e-2)" "unprognostic (1.13e-3)" "unprognostic (3.45e-1)" "unprognostic (1.43e-5)" 0.1 0.2 0.5 0.9 0.6 0.8 0.1 0.4 1.8 0.1 0.4 0.2 0.7 0.0 0.0 0.4 0.2 0.5 0.0 0.9 0.4 0.1 0.2 0.4 1.1 0.4 0.4 0.1 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.1 0.5 0.1 0.0 0.3 0.7 0.0 0.5 2.2 0.6 0.1 0.4 1.7 0.1 0.0 0.8 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.4 1.8 0.9 0.4 0.4 0.4 0.4 0.5 0.4 0.4 0.0 0.0 0.0 2.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 9.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.3 4.0 0.3 0.0 0.9 0.0 1.0 2.0 0.0 0.0 13.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 196.9;Hepatic stellate cells: 124.2;Inhibitory neurons: 326.3;Oligodendrocyte precursor cells: 262.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 19.6;fHDF/TERT166: 16.5;HEL: 35.9;HSkMC: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" 7.0 2.8 9.4 2.1 13.2 0.2 5.1 93.1 8.7 8.4 0.0 6.5 1.2 7.4 3.6 2.5 4.7 5.0 8.2 13.1 2.3 1.4 0.6 3.8 1.3 1.4 12.8 4.7 1.0 1.0 3.0 5.8 4.6 2.5 2.4 5.2 3.1 2.4 3.9 2.4 2.5 6.5 4.2 1.9 2.7 3.6 3.6 0.5 3.7 4.8 1.1 3.8 3.9 1.2 0.0 0.0 0.4 1.9 5.0 7.2 0.0 7.6 11.6 5.0 7.6 0.0 0.0 19.6 0.0 16.5 0.0 0.0 4.0 0.5 3.3 0.0 3.2 35.9 0.0 0.0 1.9 0.0 0.0 13.6 0.0 8.4 0.4 0.0 10.8 0.0 0.1 0.0 1.3 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 6.0 0.0 0.0 0.0 7.8 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.8 0.0 6.3 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 13.2 93.1 8.7 13.1 2.3 1.4 12.8 4.6 4.2 3.6 1.2 44.9 0.0 1.1 90.8 0.1 6.2 0.2 0.0 0.6 142.1 1.2 5.1 46.0 0.0 0.6 0.0 16.7 1.1 0.5 0.2 1.9 0.0 2.6 1.1 65.8 64.3 47.7 2.7 196.9 0.2 0.3 77.7 0.5 1.1 1.3 2.1 124.2 1.5 1.9 35.3 326.3 0.6 0.0 4.1 9.4 7.5 96.3 1.2 10.6 103.0 0.0 3.9 0.0 262.4 17.3 0.2 0.0 98.9 0.0 0.3 0.0 0.1 0.0 7.2 65.7 24.4 43.1 3.3 16.8 0.9 4.8 1.1 1.1 20.7 0.0 0.1 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 218.9;Kupffer cells: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.5" "Group enriched" "Detected in many" 5 "granulocytes: 19.5;monocytes: 12.9" "Cell line enhanced" "Detected in many" "HaCaT: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 40.5 22.7 33.5 14.5 36.4 18.9 11.2 25.5 29.4 12.2 16.9 16.6 25.8 13.5 8.7 28.5 16.5 13.6 19.4 27.1 30.2 16.0 32.9 18.8 8.2 32.9 31.3 21.7 25.4 45.1 3.5 14.5 30.8 15.6 10.0 5.4 21.7 17.1 106.5 88.1 28.0 11.1 30.4 25.1 14.7 7.9 42.7 6.0 17.6 51.9 7.6 16.2 8.2 22.6 19.6 36.4 14.7 21.9 42.8 19.1 66.7 14.1 16.1 9.6 6.5 20.7 28.0 0.0 25.8 22.5 15.1 105.5 7.7 32.8 2.9 26.3 7.2 0.1 47.5 30.0 20.4 18.8 4.8 29.0 52.1 11.5 10.6 12.9 12.8 1.6 26.0 1.1 8.7 61.8 1.1 59.5 17.5 63.4 16.9 7.4 30.3 36.7 12.2 64.3 17.2 10.5 37.3 46.9 10.6 7.1 44.9 78.8 16.5 16.2 23.4 17.4 9.7 1.7 0.2 0.4 11.6 33.9 12.7 1.3 8.1 6.6 1.4 12.9 0.2 0.3 0.9 1.0 3.2 0.1 0.2 1.2 19.5 2.2 11.2 0.7 1.2 3.2 33.5 36.4 25.5 29.4 27.1 30.2 32.9 31.3 30.8 30.4 42.7 22.6 32.1 32.1 22.9 36.2 4.6 34.5 16.5 21.1 12.5 6.0 16.7 14.4 38.8 72.9 26.2 9.2 25.0 30.1 11.0 72.3 1.9 13.9 4.3 19.8 16.6 28.9 9.6 30.9 9.1 14.1 29.5 23.7 17.9 17.4 1.3 21.3 71.0 218.9 31.9 33.7 17.6 21.2 10.2 134.2 30.0 18.8 32.3 50.4 12.4 10.3 80.4 36.5 14.4 29.1 6.0 15.9 32.4 21.1 7.4 17.7 55.6 19.9 34.4 19.9 19.7 34.6 30.6 0.9 9.4 34.4 46.9 23.9 12.6 15.5 27.5 32.8 S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3574.5;kidney: 1380.0;urinary bladder: 1097.4" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 11464.4;Basal prostatic cells: 4796.7;Basal respiratory cells: 10600.9;Basal squamous epithelial cells: 4741.9;Club cells: 3331.1;Prostatic glandular cells: 9446.4;Squamous epithelial cells: 9013.7;Suprabasal keratinocytes: 3626.5;Urothelial cells: 5382.7" "Cancer enhanced" "Detected in all" "cervical cancer: 848.8;head and neck cancer: 1229.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.1" "Group enriched" "Detected in many" 5 "HBEC3-KT: 21286.9;RT4: 8382.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 27000 "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: AB_2684767" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (1.57e-2)" "unprognostic (1.42e-3)" "unprognostic (1.98e-1)" "unprognostic (3.20e-1)" "unprognostic (4.21e-4)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.52e-2)" "unprognostic (8.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" 4.0 2.1 2.5 4.1 2.7 1.0 17.3 2.4 3.6 279.9 2.0 3.1 0.8 2.5 16.1 3574.5 5.6 1.8 3.9 2.3 3.2 1380.0 1.7 12.0 0.5 4.1 3.0 1.9 2.1 0.1 5.4 0.8 3.0 48.1 1.6 0.4 377.1 16.9 3.3 429.6 1.6 1.9 3.0 1.5 3.6 2.8 3.4 6.3 11.9 1.4 416.1 1097.4 747.3 3.5 827.0 9.3 1.1 0.9 10.8 4.2 1.2 10.4 11.5 9.0 7.8 2.1 26.8 1.2 418.3 17.8 18.3 2001.4 1.3 21286.9 9.9 5.4 3.7 3.8 56.2 5.0 4.5 0.7 1.9 8.8 2777.8 24.1 3135.5 21.7 13.2 0.0 0.8 1.5 47.7 3.4 0.2 0.2 2.2 22.3 155.4 1.3 497.9 2.1 502.4 8382.8 16.5 0.5 34.9 5.8 9.0 5.9 3.2 5.7 6.0 12.5 692.6 92.4 280.6 1.9 2.4 4.7 26.5 1.8 24.2 10.1 0.4 0.0 2.3 0.0 1.4 0.4 1.6 1.3 0.3 0.0 0.4 0.3 4.3 0.0 0.5 2.2 1.6 0.7 2.5 2.7 2.4 3.6 2.3 3.2 4.1 3.0 3.0 3.0 3.4 3.5 1.4 9.6 17.3 2.6 1.0 11464.4 4796.7 10600.9 4741.9 0.0 22.2 35.4 2.9 1.5 3331.1 218.8 0.0 0.7 0.8 3.2 1226.7 24.8 4.5 16.3 2.5 108.2 1.8 3.0 0.1 27.6 1.0 130.8 1.5 24.5 17.1 1.2 0.4 0.1 1.8 0.0 0.0 1.6 789.4 0.8 676.4 8.1 0.6 18.0 759.5 0.0 5.3 1.1 0.0 2.0 0.1 668.7 2.5 0.7 25.9 9446.4 0.8 11.8 560.8 0.1 0.0 5.5 207.0 0.6 3.0 9013.7 3626.5 0.3 37.8 8.9 2.0 5382.7 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 S100B S100beta ENSG00000160307 "S100 calcium binding protein B" P04271 21 46598604-46605208 "Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 1499.3;choroid plexus: 781.0" "Cell type enhanced" "Detected in many" "Astrocytes: 126.3;Breast myoepithelial cells: 124.8;Granulosa cells: 261.7;Langerhans cells: 206.8;Melanocytes: 99.6;Oligodendrocytes: 332.1" "Group enriched" "Detected in all" 58 "glioma: 463.5;melanoma: 495.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 360.9" "Lineage enriched" "Detected in all" 6 "T-cells: 360.9" "Group enriched" "Detected in some" 7 "SK-MEL-30: 547.1;WM-115: 992.8" "CAB000073, HPA015768, CAB078196" Enhanced Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 300000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "CAB000073: AB_10013383, CAB078196: AB_2665776, HPA015768: AB_1856538" "unprognostic (5.67e-3)" "unprognostic (6.39e-3)" "unprognostic (2.08e-3)" "unprognostic (2.08e-2)" "unprognostic (4.54e-3)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.68e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.57e-3)" "unprognostic (6.70e-2)" "unprognostic (4.41e-7)" "unprognostic (3.55e-2)" "unprognostic (7.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" 151.1 25.7 877.1 10.5 1072.5 2.3 87.0 1254.5 1191.2 28.6 781.0 121.0 7.4 2.4 12.1 14.6 6.9 14.3 28.1 858.4 989.0 3.6 3.2 6.4 21.4 1491.0 1054.2 5.6 5.0 0.3 44.7 0.8 1359.0 29.3 14.2 14.1 19.3 26.2 3.6 15.8 36.3 6.8 1162.2 26.2 23.6 2.4 998.8 18.4 5.2 6.4 20.3 15.9 26.9 1499.3 0.5 0.0 110.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.9 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 15.9 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 2.5 0.0 0.0 547.1 0.0 0.1 0.5 0.0 0.3 0.3 0.0 3.2 0.0 0.3 0.0 1.4 6.7 992.8 0.1 0.5 0.2 360.9 9.5 103.3 0.2 1.0 67.6 16.3 1.4 3.2 153.1 3.2 58.7 10.1 3.9 0.0 63.6 877.1 1072.5 1254.5 1191.2 858.4 989.0 1491.0 1054.2 1359.0 1162.2 998.8 1499.3 4.5 3.2 4.8 126.3 4.6 16.8 0.7 0.0 17.6 1.3 41.2 124.8 6.0 0.0 0.0 0.0 0.0 0.0 14.7 0.1 0.0 0.1 0.4 0.1 0.1 2.7 0.0 2.7 0.9 0.0 0.1 4.4 0.5 0.2 0.0 261.7 4.6 0.4 9.3 0.0 1.4 0.0 0.0 38.6 206.8 1.7 5.6 37.0 99.6 9.4 33.3 25.7 63.8 83.4 332.1 0.1 0.0 0.0 2.2 0.1 0.0 0.1 0.0 4.7 0.0 5.6 7.8 0.1 0.1 0.7 12.6 0.1 37.9 0.0 0.2 0.4 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 S1PR2 "AGR16, DFNB68, EDG5, Gpcr13, H218" ENSG00000267534 "Sphingosine-1-phosphate receptor 2" O95136 19 10221433-10231331 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 92.9;Early spermatids: 92.3;Late spermatids: 184.9;Syncytiotrophoblasts: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 45.0" "Group enriched" "Detected in many" 8 "granulocytes: 45.0;T-cells: 12.4" "Cell line enhanced" "Detected in many" "BEWO: 29.4;Daudi: 54.1;U-266/70: 38.9;U-698: 57.3;WM-115: 38.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014255, HPA014307" Approved Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nuclear speckles" "HPA014255: , HPA014307: AB_1847989" "unprognostic (5.38e-3)" "unprognostic (1.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" "unprognostic (1.05e-3)" "unprognostic (8.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.84e-1)" "unprognostic (1.70e-1)" "unprognostic (7.40e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.36e-10)" "unprognostic (4.91e-2)" "unprognostic (4.56e-2)" "unprognostic (3.11e-1)" "unprognostic (8.09e-2)" 7.7 2.5 1.9 6.4 1.8 1.2 5.5 1.7 1.8 10.4 1.9 4.8 1.8 8.3 2.7 3.3 8.4 6.2 6.6 1.6 2.0 3.1 5.6 13.7 10.9 2.8 1.9 5.6 2.9 2.5 3.0 18.5 2.2 6.9 2.4 1.2 4.1 2.3 0.8 5.4 4.8 4.2 2.0 1.9 4.3 13.2 2.1 1.4 3.4 1.3 10.9 8.3 7.0 2.9 3.0 0.4 3.4 6.9 18.2 22.2 29.4 4.4 8.9 1.9 4.1 1.9 1.7 54.1 5.1 8.2 2.3 1.7 1.2 2.1 1.3 5.5 2.7 1.2 1.2 1.3 6.1 1.4 1.1 12.2 1.1 3.8 1.3 5.3 0.2 2.6 1.3 11.1 1.3 2.5 0.6 2.5 3.4 0.9 1.7 3.8 1.4 2.0 1.6 2.5 2.4 4.7 2.5 1.5 3.8 2.6 1.2 1.3 0.4 6.9 2.2 15.9 1.3 38.9 19.6 57.3 2.6 2.7 38.6 45.0 2.8 0.6 7.2 2.4 8.9 0.3 9.2 7.0 2.6 0.5 3.7 3.8 0.7 3.6 1.0 0.4 12.4 2.0 1.9 1.8 1.7 1.8 1.6 2.0 2.8 1.9 2.2 2.0 2.1 2.9 2.0 0.0 1.1 0.3 2.0 0.0 4.6 0.0 1.2 0.6 8.3 4.6 0.6 2.8 0.6 1.8 2.1 92.9 5.4 0.0 0.0 3.6 92.3 8.6 21.5 2.0 2.4 0.0 0.3 3.3 18.1 17.7 0.0 18.1 0.0 2.0 3.9 7.6 13.2 0.0 0.9 0.5 0.0 3.1 0.0 184.9 22.1 7.2 0.0 0.0 4.0 7.1 3.1 6.6 0.5 2.7 0.3 13.2 2.6 4.9 0.0 0.9 0.0 0.5 13.1 2.0 4.6 1.5 1.2 2.0 0.0 68.4 4.2 1.1 0.2 4.1 SAA1 "PIG4, SAA, TP53I4" ENSG00000173432 "Serum amyloid A1" P0DJI8 11 18266260-18269977 "Disease related genes, Predicted secreted proteins" "Acute phase" Heparin-binding Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 48144.3" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 99298.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 1249.6" "Group enriched" "Detected in some" 5 "midbrain: 3.8;pons: 2.6;thalamus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 716.4" "Secreted to blood" NA NA 300000000 11000000000 "Cluster 7: Monocytes - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (1.50e-1)" "unprognostic (4.54e-3)" "unprognostic (1.79e-2)" "unprognostic (1.63e-2)" "unprognostic (7.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-2)" "unprognostic (8.95e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.57e-12)" "unprognostic (5.15e-2)" "unprognostic (9.78e-2)" "unprognostic (9.23e-3)" "unprognostic (1.64e-1)" 2040.4 54.4 0.1 161.7 0.2 0.0 1382.7 0.1 0.6 258.0 1.8 40.3 1.4 2.2 0.2 51.1 56.6 33.6 23.2 0.3 0.3 29.5 48144.3 98.5 1.1 0.8 3.8 3.3 46.7 0.5 66.6 7.2 2.6 66.5 6.4 0.0 2368.1 4.4 511.6 88.6 75.0 18.8 0.1 38.8 42.0 1.7 6.0 52.1 18.1 0.2 15.7 63.9 29.0 0.1 49.2 0.3 0.0 0.3 34.4 0.2 18.9 1.3 1.1 0.2 0.3 0.1 17.2 0.0 38.3 0.0 11.7 45.5 0.0 716.4 0.3 0.6 0.0 0.8 0.0 0.1 148.4 1.1 0.0 60.9 66.7 0.2 76.7 0.1 0.0 0.0 0.1 0.0 9.3 0.1 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 28.5 0.9 0.0 0.1 4.2 5.5 0.2 0.0 0.5 0.0 0.0 0.2 5.5 0.0 1.3 0.0 1.3 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.3 0.3 0.8 3.8 2.6 0.1 6.0 0.1 107.2 6.4 2.8 0.0 259.8 9.3 64.9 10039.5 10.2 0.0 210.6 1010.4 0.1 1701.5 7604.7 55.2 0.0 1.3 3.0 44.5 0.0 250.4 0.0 12.6 1.6 114.9 1.8 3543.7 0.1 81.1 34.4 8.3 0.0 14.3 2.5 0.0 2568.6 99298.7 1.0 0.0 0.1 5.2 2012.1 2454.9 0.3 0.0 0.0 2.6 51.6 0.0 2.6 0.0 1.0 0.0 0.1 68.8 5.5 0.0 0.1 185.5 3.1 0.2 15716.2 0.0 0.0 31.5 736.1 0.0 0.0 34.1 0.1 2.1 214.7 0.0 36.7 178.8 SAA2 ENSG00000134339 "Serum amyloid A2" P0DJI9 11 18239223-18248668 "Disease related genes, Predicted secreted proteins" "Acute phase" Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 36265.6" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 55342.6" "Cancer enriched" "Detected in many" 22 "liver cancer: 150.5" "Group enriched" "Detected in some" 9 "midbrain: 6.3;pons: 4.8;thalamus: 7.7" "Immune cell enhanced" "Detected in some" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 27.8;EFO-21: 20.2;GAMG: 19.6;HaCaT: 25.0;HBEC3-KT: 55.4;HSkMC: 17.6" "Secreted to blood" NA NA 9200000000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.73e-3)" "unprognostic (4.42e-2)" "unprognostic (2.63e-1)" "unprognostic (5.03e-2)" "unprognostic (1.40e-3)" "unprognostic (7.12e-2)" "unprognostic (7.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.57e-1)" "unprognostic (2.86e-2)" "unprognostic (2.78e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (1.53e-1)" "unprognostic (9.72e-2)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" 562.3 16.9 0.0 137.9 0.1 0.4 321.5 0.5 0.7 277.0 0.6 11.5 0.9 1.0 0.2 22.1 21.1 14.0 8.3 0.1 0.1 12.8 36265.6 35.7 0.6 0.2 6.3 1.7 13.9 0.2 31.1 1.7 4.8 38.5 1.3 0.6 1796.2 1.6 221.2 25.7 21.0 6.5 0.0 20.1 18.1 2.1 7.7 16.3 6.6 0.2 6.8 22.4 7.8 0.7 27.8 0.1 0.2 0.2 1.0 0.0 3.6 0.1 0.8 0.1 0.3 0.0 12.1 0.1 20.2 0.2 19.6 25.0 0.0 55.4 0.1 1.2 0.0 1.0 0.5 0.0 7.8 0.8 0.1 17.6 7.4 0.0 8.9 0.6 0.2 0.0 0.0 0.9 1.5 0.0 0.2 0.0 0.5 0.4 0.0 0.2 0.7 0.0 12.4 1.3 0.3 0.0 1.7 8.5 0.1 0.5 0.4 0.5 0.2 0.2 1.2 0.5 1.2 0.5 0.3 1.7 0.1 1.1 0.3 1.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.4 0.1 0.1 1.1 0.1 0.2 0.2 0.2 0.1 0.0 0.1 0.5 0.7 0.1 0.1 0.2 6.3 4.8 0.0 7.7 0.7 7.6 0.0 1.5 0.0 184.4 1.0 5.6 4629.9 0.6 0.0 56.8 68.5 0.2 1052.3 4596.4 3.7 0.0 0.4 0.8 21.9 0.0 70.3 1.6 12.3 0.9 68.2 0.0 2356.0 0.0 34.4 2.3 2.0 0.0 13.5 0.0 0.0 1442.8 55342.6 0.4 0.0 0.0 1.1 1204.4 1502.7 0.0 0.5 0.0 0.6 8.8 0.0 1.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.1 34.5 2.9 0.1 11449.8 0.0 0.0 3.1 400.9 0.3 0.0 5.6 0.1 0.5 144.2 0.0 5.3 65.4 SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Cell type enhanced" "Detected in many" "dendritic cells: 157.0;NK-cells: 271.9;Plasma cells: 43.7;T-cells: 84.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.4;T-cells: 113.8" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.8;HDLM-2: 3.4;hTEC/SVTERT24-B: 2.2;hTERT-RPE1: 1.9;NTERA-2: 1.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "HPA028992, HPA028993" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA028992: AB_10598914, HPA028993: AB_10601891" "unprognostic (2.91e-3)" "unprognostic (5.35e-3)" "unprognostic (4.15e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-2)" "unprognostic (2.48e-4)" "unprognostic (1.20e-2)" "unprognostic (2.42e-3)" "unprognostic (2.39e-2)" "unprognostic (2.46e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.07e-6)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (3.45e-2)" 1.1 2.3 1.4 4.0 2.0 4.2 0.9 0.6 1.6 2.9 0.6 1.2 0.7 4.4 1.9 0.7 1.5 2.3 0.5 2.9 1.2 1.1 1.7 3.3 10.4 0.8 2.0 1.8 1.2 0.1 4.8 0.7 0.9 0.7 2.3 1.4 0.7 0.4 0.8 0.5 1.4 1.7 0.4 9.3 1.6 3.2 1.9 6.3 0.8 0.7 4.2 1.3 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.3 0.5 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.8 3.4 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.3 0.0 2.2 0.1 1.9 0.2 0.4 0.1 0.0 0.2 0.0 0.1 0.0 1.7 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.5 113.8 0.4 90.0 2.5 39.8 102.1 0.6 0.3 28.8 68.9 2.3 128.4 0.6 0.6 41.7 41.4 1.4 2.0 0.6 1.6 2.9 1.2 0.8 2.0 0.9 0.4 1.9 0.4 1.1 0.0 2.3 1.3 2.3 0.4 0.0 0.0 0.6 3.0 0.6 0.5 0.8 0.0 0.0 0.0 0.0 0.0 157.0 1.6 0.0 0.2 25.4 1.0 2.1 0.8 3.6 6.6 12.1 0.0 0.0 0.7 0.0 0.5 1.3 14.8 2.9 0.4 0.0 0.0 5.7 0.3 0.0 3.4 1.4 6.7 0.6 1.8 5.4 12.2 2.3 0.0 271.9 1.5 0.6 0.0 1.5 1.9 43.7 0.0 0.1 0.6 0.7 0.4 0.0 0.3 1.4 2.3 1.6 0.2 0.4 0.0 84.3 2.0 0.5 0.1 SAMD9L "C7orf6, FLJ39885, KIAA2005" ENSG00000177409 "Sterile alpha motif domain containing 9 like" Q8IVG5 7 93130056-93148385 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.3" "Cell type enhanced" "Detected in many" "monocytes: 64.8;NK-cells: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 54.0;GAMG: 44.1;HDLM-2: 51.2;Karpas-707: 131.4" "Low region specificity" "Detected in all" "HPA019461, HPA019465, HPA019488" Enhanced Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA019461: AB_1856555, HPA019465: AB_2183384, HPA019488: AB_1856557" "unprognostic (6.93e-3)" "unprognostic (6.12e-2)" "unprognostic (5.00e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (5.03e-2)" "unprognostic (7.10e-2)" "unprognostic (4.21e-2)" "unprognostic (2.32e-1)" "unprognostic (6.18e-3)" "unprognostic (1.05e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.63e-5)" "unprognostic (1.36e-1)" "unprognostic (2.07e-2)" "unprognostic (1.85e-2)" "unprognostic (1.22e-1)" 10.2 6.0 4.0 24.4 4.6 10.0 7.5 3.6 4.4 7.2 3.7 10.5 11.5 7.3 4.5 6.3 6.5 13.8 6.2 3.6 4.9 6.8 6.1 21.9 27.1 9.5 4.5 9.1 3.2 1.9 3.9 12.6 5.9 4.3 11.4 2.4 12.9 4.2 2.9 4.1 11.7 9.1 8.0 38.3 14.4 2.9 5.4 22.9 6.7 4.6 16.2 11.9 6.3 6.3 7.2 0.4 0.0 0.4 9.3 18.7 0.2 6.2 25.7 34.5 54.0 0.0 15.9 4.7 7.7 16.7 44.1 3.1 0.0 2.2 5.5 51.2 0.0 4.3 1.9 0.0 7.5 9.6 7.0 7.2 0.8 6.9 1.0 6.4 15.1 7.1 0.0 131.4 14.6 0.0 15.3 8.5 0.5 0.0 1.8 6.3 2.2 11.0 1.8 0.6 0.0 0.3 1.3 0.2 9.8 0.1 0.4 5.0 35.8 10.1 2.2 29.6 3.8 36.4 13.0 1.3 10.6 8.6 10.1 30.1 6.7 16.7 13.4 13.3 11.6 15.1 7.4 10.0 6.3 10.3 4.3 7.7 29.2 8.2 12.8 4.7 11.8 4.0 4.0 4.6 3.6 4.4 3.6 4.9 9.5 4.5 5.9 8.0 5.4 6.3 37.4 35.3 11.2 15.7 28.5 2.3 2.3 6.0 4.6 0.0 8.0 5.5 1.8 2.8 9.6 11.0 0.0 0.3 34.2 18.8 9.8 12.7 0.1 4.9 16.3 28.0 1.2 10.1 0.2 5.7 1.0 14.3 20.4 2.4 34.2 12.2 27.5 0.4 24.4 0.0 0.1 12.6 6.1 20.4 12.9 1.1 9.6 36.5 7.2 44.0 64.8 14.1 91.6 0.0 0.2 16.2 50.2 11.7 28.1 3.1 5.1 4.2 18.6 0.4 6.6 15.0 7.7 0.3 0.2 4.1 2.3 0.1 34.0 12.2 4.1 8.0 SAMM50 "CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W" ENSG00000100347 "SAMM50 sorting and assembly machinery component" Q9Y512 22 43955442-44010531 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034537 Enhanced Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034537: AB_10602794" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.95e-3)" "prognostic favorable (2.63e-7)" "unprognostic (2.43e-3)" "unprognostic (2.28e-1)" "unprognostic (5.28e-3)" "unprognostic (1.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.42e-1)" "unprognostic (3.52e-1)" "prognostic favorable (4.43e-8)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" 41.7 50.6 26.1 27.0 27.0 32.5 35.8 29.8 30.6 43.4 31.1 35.6 50.8 27.0 29.3 31.7 41.9 29.3 65.5 27.1 29.2 48.8 37.2 22.2 34.6 29.8 28.5 40.0 33.3 114.4 24.4 20.1 30.4 26.5 35.5 25.5 35.2 25.1 240.4 35.9 38.3 27.7 27.0 24.4 43.8 26.1 28.5 34.4 28.1 177.0 37.0 27.9 24.0 28.0 64.6 59.8 57.1 69.5 72.2 75.9 79.8 61.7 65.7 89.1 76.4 86.1 46.0 105.9 44.3 70.8 51.4 75.6 85.4 82.6 79.7 29.4 105.3 57.5 73.9 102.6 50.4 184.0 83.1 88.3 64.7 77.0 35.5 62.3 93.1 49.9 49.9 34.0 80.9 91.7 72.6 72.0 56.0 77.4 70.9 83.8 61.8 85.9 74.4 81.0 34.1 55.4 68.3 72.2 104.1 60.4 67.7 59.8 57.7 57.3 68.8 53.6 51.2 50.1 74.4 82.1 72.0 66.3 58.7 47.5 39.2 46.9 39.8 39.0 55.4 55.1 36.6 40.5 67.7 51.0 37.8 36.0 6.1 39.1 31.8 26.7 45.7 40.2 26.1 27.0 29.8 30.6 27.1 29.2 29.8 28.5 30.4 27.0 28.5 28.0 52.9 35.3 18.9 10.4 31.6 20.6 27.0 72.0 30.7 20.1 32.1 40.9 68.6 18.6 39.5 9.2 8.4 41.6 31.7 36.1 60.7 47.2 40.3 47.3 24.9 35.1 18.6 51.4 12.0 55.5 54.1 24.6 42.3 32.7 27.3 43.9 30.0 41.8 51.1 32.0 12.7 35.2 46.8 28.6 20.5 50.1 26.1 25.0 16.0 12.2 41.4 32.8 33.0 9.5 9.1 43.7 34.5 30.5 31.0 16.2 82.4 116.8 39.9 30.1 19.7 23.2 33.4 45.8 31.2 34.3 22.6 20.5 28.5 69.9 59.8 19.3 SAP25 FLJ00248 ENSG00000205307 "Sin3A associated protein 25" Q8TEE9 7 100572228-100573900 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 57.8;Spermatogonia: 86.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 30.4;NB-4: 69.1;OE19: 117.4;U-937: 27.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA062610 Approved "Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear bodies" "HPA062610: AB_2684806" "unprognostic (1.70e-1)" "unprognostic (7.87e-2)" "unprognostic (1.09e-5)" "unprognostic (6.89e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-3)" "unprognostic (9.96e-2)" "unprognostic (4.26e-2)" "unprognostic (2.83e-1)" "unprognostic (5.04e-2)" "unprognostic (6.57e-3)" "unprognostic (1.71e-2)" "unprognostic (7.52e-6)" "unprognostic (7.36e-2)" "unprognostic (1.78e-1)" "unprognostic (1.39e-1)" "unprognostic (4.18e-3)" 8.8 4.5 18.7 17.9 21.0 28.9 4.7 19.9 26.2 11.1 18.0 5.8 6.5 4.8 0.3 4.4 9.3 5.0 6.6 18.6 20.5 15.8 7.0 14.7 28.6 22.1 19.3 23.2 6.5 1.0 12.9 5.3 20.9 11.0 1.7 13.5 8.3 2.4 3.9 6.1 20.0 2.0 18.5 47.4 5.6 25.4 21.6 17.6 15.8 1.1 8.2 5.0 7.4 24.9 4.0 1.4 2.8 1.6 0.2 0.4 6.4 3.0 0.6 1.9 0.9 3.1 4.1 2.0 1.8 0.0 0.2 4.2 0.5 0.9 0.2 3.9 2.3 3.7 3.6 1.0 0.6 4.2 30.4 0.8 1.9 1.1 0.4 1.5 0.6 8.0 4.7 7.7 0.4 9.2 7.8 69.1 4.3 117.4 1.5 16.7 0.9 3.1 0.3 1.2 1.6 5.0 0.4 3.7 4.5 3.1 5.6 15.8 3.2 2.9 6.1 2.7 2.9 13.1 3.4 1.6 0.9 27.4 3.0 0.9 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 1.1 0.0 0.2 0.3 0.0 0.0 18.7 21.0 19.9 26.2 18.6 20.5 22.1 19.3 20.9 18.5 21.6 24.9 2.2 0.0 4.1 11.1 6.7 0.0 1.3 0.0 1.2 23.7 4.6 5.3 0.0 7.2 1.3 0.0 70.9 2.6 8.7 3.1 0.0 1.9 1.4 2.1 2.0 1.7 0.0 3.4 0.9 0.7 0.7 1.3 4.1 3.2 1.3 6.0 2.5 1.1 3.1 21.9 0.9 2.3 0.0 8.5 0.0 4.6 3.4 10.7 0.0 9.4 6.5 8.0 5.2 2.5 8.2 2.0 1.9 1.2 4.1 2.8 4.9 0.3 0.0 57.8 6.6 1.5 1.8 17.2 86.6 1.5 0.0 3.6 8.2 0.9 1.5 1.8 SAR1A "SAR1, Sara, SARA1" ENSG00000079332 "Secretion associated Ras related GTPase 1A" Q9NR31 10 70147289-70170523 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, CAB022545, HPA048368" Supported Supported "Endoplasmic reticulum" NA NA 660000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "CAB022545: , HPA006923: AB_1856577, HPA048368: AB_2680373" "unprognostic (3.77e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-3)" "unprognostic (3.13e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (7.00e-5)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.60e-2)" "unprognostic (1.00e-1)" "unprognostic (1.02e-2)" "unprognostic (4.06e-2)" "unprognostic (2.06e-1)" "unprognostic (2.38e-3)" "unprognostic (1.76e-1)" "unprognostic (4.80e-2)" "unprognostic (1.10e-2)" "unprognostic (7.13e-2)" 77.1 52.8 41.8 38.4 43.5 163.2 48.1 45.1 45.7 43.1 53.3 39.1 26.6 41.0 47.0 41.4 37.3 35.0 44.8 43.8 48.3 43.3 70.2 51.4 36.7 42.8 44.9 41.0 33.9 44.2 37.9 76.0 44.0 38.9 35.5 42.0 39.9 38.9 51.1 38.5 34.5 49.7 47.3 40.7 37.9 23.5 48.4 33.2 39.8 56.3 38.4 45.8 36.2 52.1 85.8 56.3 75.7 131.9 246.1 143.1 61.1 128.3 154.4 115.6 140.0 169.7 78.2 74.4 67.1 153.7 52.8 96.6 94.5 75.9 111.6 103.9 44.3 54.1 65.8 82.5 112.4 86.7 56.6 155.9 68.4 76.4 133.2 119.0 63.8 55.9 68.7 105.9 110.0 60.0 73.8 72.6 65.2 55.6 141.3 70.8 84.4 42.5 88.7 69.7 42.6 73.8 98.0 134.6 72.2 66.8 65.8 59.7 88.6 63.7 94.3 92.2 91.3 72.3 141.3 114.0 84.9 111.7 48.7 75.5 63.5 74.0 88.0 80.9 94.8 47.7 68.5 85.9 58.5 38.6 65.7 88.7 67.9 103.3 72.9 44.8 53.2 95.9 41.8 43.5 45.1 45.7 43.8 48.3 42.8 44.9 44.0 47.3 48.4 52.1 88.4 128.2 110.2 6.8 53.5 235.7 138.0 120.2 25.0 38.6 99.2 62.4 74.7 57.2 105.3 49.7 33.3 120.6 109.8 51.6 54.8 78.4 3.0 52.3 85.8 85.2 42.7 46.1 21.2 77.3 199.0 127.8 23.9 89.7 53.2 46.3 69.7 114.1 101.0 26.9 22.2 72.1 65.1 51.2 208.9 5.6 54.7 68.1 113.8 21.5 58.4 61.9 75.2 16.1 26.4 78.8 56.2 58.6 97.7 141.4 59.1 95.9 67.1 33.4 78.9 73.7 158.8 64.1 51.8 37.2 248.8 238.9 86.3 45.2 53.2 175.2 SASH3 "753P9, CXorf9, HACS2, SH3D6C, SLY" ENSG00000122122 "SAM and SH3 domain containing 3" O75995 X 129779949-129795201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 108.1;intestine: 36.5;lymphoid tissue: 120.7" "Cell type enhanced" "Detected in some" "B-cells: 69.5;dendritic cells: 66.3;Hofbauer cells: 51.3;Kupffer cells: 58.9;Macrophages: 40.0;monocytes: 45.3;NK-cells: 101.0;Plasma cells: 39.8;T-cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 164.1;JURKAT: 119.4;MOLT-4: 120.6;NB-4: 89.1;REH: 88.5;U-698: 150.2;U-937: 117.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001085 Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 14000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA001085: AB_2184289" "unprognostic (1.88e-2)" "unprognostic (5.82e-3)" "unprognostic (1.49e-3)" "prognostic favorable (3.15e-4)" "unprognostic (1.12e-1)" "unprognostic (1.19e-3)" "unprognostic (1.67e-1)" "unprognostic (3.23e-3)" "unprognostic (7.92e-3)" "unprognostic (3.45e-1)" "unprognostic (8.75e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.51e-5)" "unprognostic (3.30e-1)" "unprognostic (3.56e-2)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" 8.6 5.6 5.2 61.8 5.6 108.1 4.3 5.4 7.4 3.2 5.1 9.4 11.6 3.1 1.8 3.6 4.9 10.2 2.7 4.8 6.4 3.7 5.9 21.3 120.6 9.6 7.0 1.8 2.5 1.5 2.2 7.5 8.4 4.2 9.9 0.2 7.9 2.2 1.3 2.1 36.5 7.5 7.5 100.3 13.6 1.3 8.4 120.7 3.9 1.7 108.2 15.4 3.0 10.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.7 0.0 0.0 0.0 58.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 119.4 0.2 13.6 0.0 0.0 120.6 89.1 0.0 0.0 0.0 88.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 24.0 0.3 0.0 0.3 0.1 0.1 0.1 35.0 150.2 0.0 117.2 0.0 41.6 135.4 245.5 192.2 195.3 159.1 79.1 108.2 178.9 121.5 90.8 76.9 120.9 128.0 153.3 209.9 55.1 145.6 343.7 5.2 5.6 5.4 7.4 4.8 6.4 9.6 7.0 8.4 7.5 8.4 10.2 0.8 0.0 3.6 0.0 69.5 0.5 0.1 0.0 0.0 0.0 0.5 1.1 1.0 1.5 0.0 0.0 0.0 0.5 66.3 0.1 0.0 0.1 0.1 0.2 0.2 1.2 0.0 13.5 0.2 0.0 0.6 0.9 2.6 0.3 22.2 0.0 3.3 0.9 51.3 0.0 0.2 0.1 0.0 58.9 19.1 0.0 0.3 40.0 0.0 7.5 45.3 0.0 101.0 0.0 0.1 0.0 0.0 0.0 39.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.1 1.3 0.5 60.6 0.0 0.1 0.0 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.6" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 141.0;Hepatocytes: 307.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" 28.6 35.3 18.4 12.6 20.4 5.7 56.6 37.1 29.3 20.7 17.6 23.2 48.2 15.1 73.2 39.6 16.5 18.2 22.0 19.9 29.9 49.1 393.6 24.6 13.5 42.9 28.0 16.9 21.5 48.6 15.6 14.7 39.1 101.4 19.9 29.5 22.4 56.6 7.7 13.8 24.7 16.2 32.2 8.8 21.7 24.3 24.6 13.5 23.9 13.0 19.5 21.5 27.1 36.5 26.5 14.3 184.8 39.5 72.1 59.9 27.8 27.8 53.5 18.2 32.4 83.1 95.9 25.4 89.0 32.3 156.6 100.8 59.2 70.9 18.1 12.5 80.0 34.6 73.4 64.4 57.9 24.8 12.5 51.0 57.4 60.4 60.2 15.6 29.8 22.8 25.0 34.6 89.0 27.4 9.4 29.2 59.8 74.4 39.7 13.2 51.0 21.6 133.6 116.5 51.1 28.8 73.4 14.6 38.0 125.4 62.2 38.6 58.3 19.0 29.7 32.5 14.0 6.4 11.2 33.3 7.0 49.5 33.5 7.8 3.7 1.0 3.5 4.9 5.9 4.4 4.7 4.2 6.5 4.1 6.8 6.7 0.3 5.3 3.6 7.7 5.5 2.6 18.4 20.4 37.1 29.3 19.9 29.9 42.9 28.0 39.1 32.2 24.6 36.5 10.4 19.2 31.9 23.8 62.6 9.7 49.9 48.9 14.8 26.8 33.7 12.4 20.8 18.6 40.8 20.2 31.3 15.9 47.5 26.4 5.9 24.1 3.0 11.5 8.8 15.7 14.4 18.1 29.6 28.9 16.7 16.3 18.3 19.6 17.7 11.1 141.0 307.1 21.0 23.5 29.4 15.3 59.0 22.1 17.0 1.3 19.3 17.6 19.6 20.6 15.6 38.7 13.4 27.6 34.0 19.3 18.8 17.0 20.9 50.1 24.1 15.8 18.7 28.3 13.1 12.9 14.7 6.7 12.7 36.2 15.5 18.6 56.5 42.8 13.3 54.4 SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 90.0" "Group enriched" "Detected in some" 4 "Fibroblasts: 174.0;Leydig cells: 135.8;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 211 "dendritic cells: 21.1" "Cell line enriched" "Detected in some" 20 "ASC diff: 229.1" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" HPA024661 Approved NA NA 1400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA024661: AB_1853902" "unprognostic (2.76e-2)" "unprognostic (7.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.53e-2)" "unprognostic (2.34e-2)" "unprognostic (4.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.13e-2)" "unprognostic (2.40e-1)" "unprognostic (4.21e-2)" "unprognostic (1.10e-1)" "unprognostic (7.09e-6)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" 60.5 4.0 0.4 7.2 0.8 0.0 34.6 0.8 1.8 16.6 4.9 38.5 8.7 2.9 8.2 21.1 23.7 22.5 90.0 0.6 0.4 1.0 4.1 20.2 2.4 0.3 0.2 11.2 2.4 0.2 5.4 12.5 0.2 8.4 33.7 0.3 29.0 3.3 15.1 31.1 26.3 6.5 0.5 3.3 27.3 11.6 0.2 3.2 21.1 34.5 2.1 77.1 36.8 0.3 0.0 7.9 0.0 0.0 229.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 11.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.1 0.4 0.8 0.8 1.8 0.6 0.4 0.3 0.2 0.2 0.5 0.2 0.3 7.1 0.0 0.0 0.0 0.1 6.5 0.1 0.0 0.6 0.0 0.5 0.6 4.6 0.0 0.0 0.0 0.0 0.1 6.7 0.2 0.0 0.0 1.5 0.7 27.9 2.4 0.0 0.0 0.3 0.0 0.4 174.0 4.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 2.9 0.0 0.0 0.0 17.0 4.6 135.8 1.3 7.2 5.6 0.0 1.9 0.0 0.0 0.2 0.0 0.0 11.3 0.8 0.1 0.0 0.0 0.0 0.1 0.0 7.4 3.6 0.7 1.1 0.9 6.0 0.1 1.1 44.5 0.3 0.1 SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Endothelial cells: 51.3;Hepatic stellate cells: 62.4;Langerhans cells: 37.7;Microglial cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 12.1;REH: 11.5;TIME: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" 15.2 5.0 1.5 3.1 1.8 0.4 12.7 1.4 3.4 5.6 1.4 5.2 0.0 6.0 0.9 2.7 6.5 2.2 11.8 1.6 1.8 7.5 7.5 16.3 2.1 2.7 1.7 2.6 3.1 0.1 3.8 4.3 2.2 4.6 1.2 0.2 4.2 0.0 5.3 3.1 5.4 1.2 1.7 25.6 4.2 1.6 1.7 0.5 18.8 1.9 1.0 5.6 4.6 2.8 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.3 12.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 1.8 1.4 3.4 1.6 1.8 2.7 1.7 2.2 1.7 1.7 2.8 65.9 22.4 17.6 6.5 0.6 3.4 0.4 0.7 1.2 1.2 0.8 0.9 3.5 0.0 2.9 3.7 4.2 0.4 2.0 4.9 1.9 0.4 0.3 0.5 0.9 51.3 0.0 3.4 5.4 0.2 0.2 2.5 4.1 1.1 3.8 0.3 62.4 2.3 9.0 0.0 3.5 4.4 0.0 15.7 37.7 0.4 1.2 10.1 3.6 26.2 4.8 0.7 0.0 0.5 1.1 0.3 1.2 1.2 0.0 0.7 3.0 0.2 3.0 2.0 0.0 2.1 3.0 0.5 0.6 0.3 2.7 1.2 1.0 1.3 2.2 0.8 SCD "FADS5, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1233.7;brain: 839.9;liver: 583.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 389.6;Granulosa cells: 187.3;Hepatocytes: 840.3;Oligodendrocytes: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 2534.2;CAPAN-2: 1824.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: AB_2685154" "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (7.79e-5)" 1233.7 131.2 408.7 25.7 525.8 23.0 261.5 535.7 522.1 43.2 156.6 42.9 93.1 15.4 25.5 107.8 5.0 28.7 47.1 349.1 457.5 18.5 583.8 142.8 17.2 775.0 508.9 49.6 22.6 79.5 10.3 19.9 637.8 100.1 39.7 17.9 112.6 11.2 6.1 27.0 36.0 15.9 574.4 15.3 25.2 51.8 538.7 18.4 13.0 7.2 21.0 22.5 41.9 839.9 411.2 373.3 777.6 536.4 2534.2 1449.4 158.2 43.4 948.3 101.6 536.6 323.8 1824.4 173.3 33.7 102.2 461.8 716.4 433.7 1549.5 88.9 59.4 179.6 97.5 219.3 653.4 488.4 136.9 100.9 795.5 459.4 395.0 688.9 273.1 196.2 375.3 275.4 513.3 41.7 646.8 155.9 163.3 270.7 120.7 106.3 72.6 287.4 550.4 443.8 455.3 48.9 185.3 85.8 399.7 834.9 224.2 447.7 291.3 79.0 10.0 115.9 9.1 89.8 141.4 81.5 262.9 184.4 416.0 65.9 0.0 0.8 0.0 1.4 1.6 2.3 0.6 0.5 0.7 2.7 0.9 0.4 1.3 0.1 1.4 0.0 1.5 0.0 1.2 408.7 525.8 535.7 522.1 349.1 457.5 775.0 508.9 637.8 574.4 538.7 839.9 3.8 54.5 389.6 34.0 15.7 3.7 4.5 121.8 0.6 6.5 16.1 6.2 11.2 28.6 66.2 0.0 6.2 3.0 4.7 21.5 0.0 14.6 52.6 13.9 9.0 12.5 25.8 15.8 4.8 67.9 71.7 15.9 25.0 26.9 6.3 187.3 32.9 840.3 34.1 26.9 5.2 16.4 52.9 113.5 4.2 93.0 3.7 21.2 58.7 8.4 10.2 11.9 2.1 18.6 451.5 29.6 2.7 1.5 3.7 31.4 16.2 4.9 31.0 6.2 0.0 3.6 25.7 2.0 1.2 26.7 2.3 17.4 6.6 97.8 38.9 8.2 SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 270.0;lung: 508.1;salivary gland: 746.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2883.9;Breast myoepithelial cells: 4199.8;Club cells: 13674.8;Respiratory ciliated cells: 3325.6;Urothelial cells: 3139.7" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 51.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NB-4: 2.3;T-47d: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" 1.8 1.5 1.1 0.2 1.2 0.5 122.4 0.7 1.2 270.0 11.7 0.5 0.6 1.5 1.2 74.8 29.9 2.9 0.7 1.1 5.9 1.5 7.0 508.1 0.4 1.4 1.6 2.0 18.2 0.0 12.6 0.1 1.0 37.9 0.0 0.0 746.5 2.4 0.3 4.9 1.0 0.0 1.2 9.4 50.7 3.0 3.0 0.8 3.1 0.0 0.8 14.5 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 20.3 2.4 17.2 13.3 1.8 3.3 4.5 10.1 0.0 5.9 5.0 0.0 0.0 51.8 0.2 4.3 2.6 1.1 1.2 0.7 1.2 1.1 5.9 1.4 1.6 1.0 1.2 3.0 1.5 36.4 173.1 1441.5 0.0 5.9 0.5 51.2 2883.9 0.6 0.0 1831.7 4199.8 0.4 1554.2 13674.8 0.0 0.0 0.0 30.4 0.1 0.0 20.5 0.1 1.6 0.1 40.5 0.0 10.7 0.2 1.6 0.3 15.2 3.6 1.7 35.3 1.0 68.9 1.1 0.4 0.0 0.0 0.1 1566.5 1.2 0.6 0.2 0.6 14.8 5.4 0.0 0.6 0.0 0.0 0.0 0.1 146.1 0.5 0.0 0.0 214.9 0.0 0.0 3325.6 0.0 0.0 1.6 305.2 0.3 4.4 140.8 0.4 0.0 20.2 0.1 0.2 3139.7 SCN5A "CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1" ENSG00000183873 "Sodium voltage-gated channel alpha subunit 5" Q14524 3 38548057-38649687 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Calmodulin-binding, Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Cardiomyopathy, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "heart muscle: 42.8" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 77.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "LHCN-M2: 27.6;RH-30: 22.8" "Group enriched" "Detected in many" 5 "amygdala: 3.1;basal ganglia: 10.1;hypothalamus: 6.0" "Region enhanced" "Detected in many" "basal ganglia: 5.4" HPA063346 Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA063346: " "unprognostic (9.29e-4)" "unprognostic (4.05e-2)" "unprognostic (9.95e-2)" "unprognostic (1.74e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (8.48e-2)" "unprognostic (7.12e-3)" "unprognostic (5.28e-2)" "unprognostic (1.16e-4)" "unprognostic (4.85e-3)" "unprognostic (1.09e-1)" "unprognostic (5.35e-2)" "unprognostic (4.95e-3)" 0.2 0.1 1.9 0.1 1.2 0.2 0.2 0.0 0.7 1.7 0.0 0.2 0.2 0.7 0.0 0.1 0.3 0.1 42.8 0.2 1.5 0.0 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.2 0.0 0.3 0.1 2.0 0.2 0.5 1.6 0.1 0.2 0.3 0.2 0.1 0.1 0.3 2.6 0.0 0.2 1.0 0.0 0.4 0.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.4 0.1 0.0 0.2 3.6 0.0 0.0 0.0 1.0 0.5 2.7 0.0 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.4 0.0 2.1 2.8 0.4 0.0 0.0 27.6 1.4 0.0 0.0 2.6 0.0 0.0 0.0 22.8 0.0 0.0 3.2 0.4 3.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.7 0.2 1.5 0.0 0.7 0.0 0.2 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 2.7 0.0 0.3 77.1 0.0 0.1 0.0 14.6 0.2 0.0 0.0 0.0 0.1 1.2 0.1 3.2 2.8 0.0 0.0 0.5 0.0 0.3 3.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 6.3 0.3 0.6 0.2 0.0 3.7 0.0 0.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.9 0.0 7.3 3.1 0.2 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.4 SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 157.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 114.0;Distal enterocytes: 230.9;Glandular and luminal cells: 189.8;Intestinal goblet cells: 180.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 6.8" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 300.5;HBEC3-KT: 202.4;hTCEpi: 85.3;RPTEC TERT1: 103.7;RT4: 114.1;SK-BR-3: 96.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA012743 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" 3.4 12.5 0.2 5.6 0.1 0.5 20.6 1.1 0.2 64.7 113.6 66.4 18.7 7.6 43.2 140.1 57.9 17.7 0.7 6.8 0.0 148.5 8.2 62.9 0.2 0.1 0.3 3.5 40.0 0.7 16.6 0.4 0.1 43.7 65.4 0.0 157.3 49.5 0.5 54.6 26.0 2.9 0.1 0.7 63.6 4.7 1.3 1.9 94.3 0.1 12.5 20.8 57.6 0.1 21.6 4.1 0.0 1.9 0.3 0.4 17.6 0.0 0.1 0.1 0.0 6.1 300.5 0.3 0.8 0.1 0.1 14.0 0.0 202.4 0.0 0.0 0.0 0.0 17.5 3.1 20.9 0.0 0.1 5.1 85.3 0.0 61.6 0.4 0.0 0.5 0.0 0.1 0.5 1.9 0.1 0.3 17.6 38.9 0.8 0.2 0.0 0.5 103.7 114.1 1.2 0.1 2.3 96.7 0.1 17.1 22.3 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.1 1.5 0.0 0.0 1.0 0.5 0.1 0.2 0.1 1.1 0.2 6.8 0.0 0.1 0.3 0.1 0.1 1.3 0.1 1.7 73.7 75.7 0.0 1.3 1.9 25.1 17.0 10.8 0.9 17.7 21.2 0.8 54.3 52.5 114.0 4.2 1.4 1.8 230.9 5.9 45.0 0.5 85.3 17.8 3.2 27.1 0.0 0.3 33.9 0.3 2.0 97.3 189.8 2.5 1.3 1.4 3.2 0.3 1.7 0.2 180.3 63.1 1.9 3.1 0.6 1.8 2.5 0.0 0.0 1.6 0.3 1.0 0.5 0.1 39.4 95.8 1.5 0.3 30.9 12.2 6.2 36.7 1.4 0.0 5.6 4.3 1.2 3.7 48.1 8.8 1.6 3.6 0.2 31.5 42.1 SCO1 SCOD1 ENSG00000133028 "Synthesis of cytochrome C oxidase 1" O75880 17 10672474-10698375 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021565, HPA021579" Enhanced NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA021565: AB_1856631, HPA021579: AB_1856632" "unprognostic (6.11e-3)" "unprognostic (2.88e-1)" "unprognostic (5.12e-3)" "unprognostic (1.09e-2)" "unprognostic (1.92e-2)" "unprognostic (7.52e-2)" "unprognostic (5.01e-2)" "unprognostic (3.02e-2)" "unprognostic (7.09e-3)" "unprognostic (1.83e-2)" "unprognostic (2.43e-3)" "unprognostic (3.84e-2)" "prognostic favorable (9.69e-7)" "unprognostic (4.94e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.12e-2)" 16.4 18.5 9.2 12.2 9.4 8.9 14.2 9.7 9.5 12.5 14.5 18.8 19.9 13.6 8.0 16.5 10.6 8.0 24.2 9.2 10.1 20.0 30.1 10.2 12.0 9.7 9.4 10.4 9.6 15.7 12.5 11.3 9.7 12.8 14.6 9.2 11.9 9.7 24.9 12.1 16.8 9.2 9.6 12.0 13.2 12.0 10.0 9.6 13.1 17.2 9.9 13.5 12.3 10.2 32.6 46.9 19.0 25.5 22.8 19.4 40.7 35.2 18.3 31.1 29.9 24.0 18.5 56.8 37.4 31.6 19.1 35.0 38.0 33.4 34.7 30.1 48.4 29.3 28.8 34.0 32.5 20.5 20.8 24.7 21.4 29.3 46.3 16.2 22.5 36.9 30.3 9.8 32.4 18.4 28.7 21.1 42.0 36.6 23.9 33.8 23.6 25.4 40.3 23.2 10.1 29.2 41.6 25.4 37.2 24.4 32.1 14.4 26.9 23.7 20.2 25.6 37.1 15.5 16.5 21.6 19.3 25.5 26.3 6.6 15.5 14.8 11.5 18.5 12.2 13.2 10.0 12.0 15.2 9.8 12.2 12.8 5.1 11.1 20.5 10.9 14.3 12.2 9.2 9.4 9.7 9.5 9.2 10.1 9.7 9.4 9.7 9.6 10.0 10.2 18.1 22.4 19.8 5.9 24.3 11.5 23.3 32.2 13.1 20.4 14.0 13.2 39.5 18.6 23.4 18.4 66.7 61.0 15.5 34.6 41.1 26.1 4.0 13.7 25.2 19.1 15.7 22.1 4.2 20.4 102.6 19.7 24.5 15.9 8.8 22.4 19.6 38.2 29.8 16.8 4.7 25.3 26.4 18.9 9.5 5.4 18.6 15.9 10.6 6.5 28.4 20.7 22.6 2.5 5.4 24.1 19.3 19.2 18.4 33.1 31.6 49.8 16.1 37.7 6.6 23.8 19.1 28.4 37.0 21.5 11.8 60.5 17.5 43.0 35.6 23.0 SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.0" "Cell type enhanced" "Detected in many" "Muller glia cells: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "WM-115: 326.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol No No 160000 "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA024517: AB_2184811" "prognostic unfavorable (8.32e-4)" "prognostic unfavorable (8.46e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.00e-5)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (1.13e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.15e-5)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (2.60e-4)" 13.9 27.9 112.4 13.1 118.9 8.1 14.3 128.2 117.9 22.2 52.2 27.5 6.5 27.4 16.2 19.0 26.0 16.5 19.8 112.5 129.0 23.7 2.6 16.4 14.3 112.5 159.0 32.4 36.7 54.5 34.0 15.8 115.5 27.9 10.4 102.5 18.0 37.2 2.4 11.1 15.8 34.3 116.1 10.8 19.3 23.0 122.5 28.9 13.5 11.0 21.6 22.0 17.8 127.1 106.3 75.0 119.9 48.6 83.1 126.9 0.5 97.0 128.8 102.5 110.0 87.1 81.8 13.0 83.7 124.7 227.3 46.7 137.7 41.2 148.9 0.6 29.0 43.8 49.7 56.6 105.9 0.3 0.5 106.5 58.1 93.5 49.6 139.4 95.9 28.0 0.5 33.3 146.6 59.5 15.5 0.1 109.4 0.2 79.6 0.3 127.7 1.1 71.7 51.5 43.7 103.1 99.9 64.1 112.5 149.7 86.3 6.9 106.7 132.2 113.3 1.7 123.7 10.8 177.0 1.1 62.4 0.5 326.5 3.7 3.4 10.3 0.9 14.1 10.7 14.0 0.2 1.0 10.9 7.6 0.7 1.4 0.5 7.1 25.4 10.8 0.0 3.5 112.4 118.9 128.2 117.9 112.5 129.0 112.5 159.0 115.5 116.1 122.5 127.1 5.9 28.9 14.1 42.7 15.4 3.1 12.6 14.0 14.2 66.9 7.6 5.2 15.8 20.0 22.3 33.1 45.9 0.4 16.2 1.1 15.6 24.1 61.1 7.3 11.9 10.9 12.1 2.5 52.0 25.1 1.9 17.2 5.6 6.7 8.2 22.9 1.8 0.3 5.4 69.0 51.4 0.7 14.2 8.8 13.9 68.1 13.7 11.1 7.2 16.9 11.5 80.8 12.3 31.2 35.6 21.2 17.3 21.1 12.5 17.4 0.1 2.8 29.2 41.1 6.6 9.6 11.9 3.1 11.0 5.1 1.7 1.0 2.8 8.5 1.2 22.3 SDCBP "MDA-9, SYCL" ENSG00000137575 "Syndecan binding protein" O00560 8 58552924-58582859 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 959.8;Melanocytes: 889.4" "Cancer enriched" "Detected in all" 4 "melanoma: 244.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1908.0" "Group enriched" "Detected in all" 5 "granulocytes: 1908.0;monocytes: 562.9" "Cell line enhanced" "Detected in many" "HHSteC: 787.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012245, HPA023840" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Nuclear membrane" "CAB012245: , HPA023840: AB_1857712" "unprognostic (2.39e-2)" "unprognostic (3.34e-2)" "unprognostic (1.84e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (2.60e-3)" "unprognostic (7.14e-2)" "unprognostic (1.04e-3)" "unprognostic (1.11e-1)" "unprognostic (5.68e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.92e-1)" 228.5 126.4 94.1 160.8 111.8 245.6 167.1 102.0 130.1 160.9 112.2 119.6 83.1 109.8 83.6 88.8 95.7 194.8 120.6 103.7 112.6 126.6 174.0 223.9 121.2 113.7 103.8 89.1 80.8 132.9 45.8 264.3 113.5 70.8 134.7 26.8 124.9 78.3 65.9 84.8 92.8 151.2 107.4 203.0 130.0 41.1 110.8 129.9 120.7 113.7 92.8 248.8 91.9 123.7 123.5 185.9 194.2 101.4 711.7 607.1 86.1 122.9 439.6 175.3 228.9 74.8 250.7 0.4 194.8 166.4 321.2 49.7 106.0 142.4 215.7 22.6 91.3 184.3 156.0 60.6 787.9 47.7 287.1 417.9 188.1 176.5 525.2 273.0 428.0 125.2 92.3 104.6 403.4 32.4 104.1 55.9 122.2 478.6 52.3 49.6 59.4 24.3 282.1 127.0 84.9 153.5 133.8 56.1 630.0 213.8 51.0 127.9 382.3 168.8 72.5 200.8 81.5 31.4 45.6 74.8 428.9 0.5 155.1 777.4 562.9 528.1 61.2 349.6 78.0 69.4 82.0 67.3 251.8 61.0 103.9 80.2 1908.0 42.6 329.1 69.9 103.0 453.2 94.1 111.8 102.0 130.1 103.7 112.6 113.7 103.8 113.5 107.4 110.8 123.7 382.7 211.5 115.9 26.8 170.3 338.7 321.2 312.5 108.1 10.8 86.7 54.6 70.6 88.6 181.3 206.0 16.7 284.3 220.2 192.9 225.0 392.9 7.8 110.9 87.0 412.7 112.3 116.6 18.5 291.6 756.8 308.1 162.1 120.5 396.9 62.9 378.3 101.9 782.5 15.2 23.7 180.3 248.2 552.1 959.8 15.9 233.9 626.0 889.4 71.2 312.4 94.3 51.5 21.6 16.3 297.9 152.9 159.9 65.1 307.4 78.4 211.2 169.8 11.1 98.6 82.7 177.4 14.8 8.4 73.3 173.2 483.0 256.2 117.0 129.2 457.6 SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" Q9BRK5 1 1216909-1232067 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 2600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" 86.5 91.8 44.2 78.8 47.8 56.2 80.2 47.2 65.3 84.4 72.5 95.9 117.1 91.8 43.9 66.3 74.6 66.2 134.6 45.5 44.8 89.6 160.7 82.0 53.4 53.2 46.1 85.4 104.6 61.5 78.5 73.3 47.0 76.9 60.4 25.7 83.5 52.2 78.9 72.9 116.8 58.2 43.5 78.0 93.6 71.7 50.5 34.6 81.8 47.7 39.6 82.2 71.6 45.9 139.7 123.7 67.1 214.0 320.0 160.4 80.5 266.1 241.4 191.2 159.4 147.0 236.2 87.8 201.8 258.0 137.4 140.4 77.5 117.1 58.2 147.9 133.0 153.6 185.7 207.8 147.4 156.7 199.2 199.0 59.5 144.6 81.2 186.5 155.9 57.3 129.2 225.0 95.7 101.1 77.8 158.9 61.7 158.0 167.1 85.8 86.5 234.4 127.2 66.4 243.3 86.7 177.2 208.2 182.8 59.0 108.0 176.7 198.8 196.2 107.0 149.5 154.2 138.9 141.2 144.6 222.9 289.7 87.1 14.4 21.5 30.8 19.3 14.6 14.6 13.5 27.6 28.4 21.9 16.8 16.0 14.1 16.9 26.8 23.2 14.0 25.1 11.8 44.2 47.8 47.2 65.3 45.5 44.8 53.2 46.1 47.0 43.5 50.5 45.9 92.9 22.4 19.2 18.6 62.5 119.8 74.0 24.6 46.7 34.5 51.2 47.6 35.7 68.6 28.9 49.7 18.8 124.1 68.4 240.0 11.7 79.0 39.1 49.0 76.2 77.8 65.5 32.8 21.1 71.4 284.4 117.1 81.1 60.8 36.2 61.4 76.4 117.1 122.4 38.7 23.5 174.9 30.5 73.7 154.8 36.8 95.4 62.8 167.2 13.1 50.8 64.9 111.2 13.6 17.5 73.0 213.5 76.0 202.5 101.5 406.2 57.7 18.4 40.0 59.2 69.8 75.1 101.7 63.5 53.2 114.2 168.0 73.4 88.7 181.0 71.1 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal respiratory cells: 325.1;Club cells: 141.9;Ionocytes: 120.1;Pancreatic endocrine cells: 99.5;Respiratory ciliated cells: 82.5;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.8;HaCaT: 10.3;hTCEpi: 16.7;OE19: 24.8;T-47d: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" 0.3 0.2 1.7 3.0 1.8 0.0 9.1 1.6 4.4 15.6 0.5 2.2 2.3 0.0 0.0 51.9 0.2 0.4 0.2 2.2 1.5 0.1 0.0 34.4 0.4 4.8 2.0 0.2 0.4 0.0 0.5 0.0 4.9 0.3 3.9 1.1 16.8 0.0 0.3 62.6 15.7 0.2 0.9 0.0 18.1 0.8 2.8 0.3 0.0 0.2 21.9 6.3 24.9 1.8 4.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 10.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 24.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.6 4.4 2.2 1.5 4.8 2.0 4.9 0.9 2.8 1.8 1.7 48.1 155.9 0.0 1.7 51.1 6.2 325.1 4.6 0.3 5.5 2.4 0.2 5.7 141.9 0.0 0.0 0.0 0.0 7.1 0.0 0.7 0.4 0.0 0.1 2.3 0.0 0.0 4.3 1.4 0.0 0.9 10.2 0.1 3.8 0.0 0.0 0.0 0.0 0.0 1.1 19.7 120.1 0.0 3.6 0.4 0.6 0.4 3.6 0.0 0.6 12.3 0.0 0.0 0.3 99.5 3.4 0.0 0.0 9.5 0.3 0.0 82.5 1.6 0.0 0.1 4.9 0.3 5.5 36.6 72.2 0.0 0.6 0.0 5.3 26.0 SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 430.3;Hepatic stellate cells: 286.3;Late spermatids: 740.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 355.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 355.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 398.1;TIME: 251.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" 66.7 54.2 42.6 44.6 63.3 65.5 57.6 75.4 60.7 39.5 36.3 19.5 21.8 24.6 28.2 31.5 27.3 34.3 50.2 49.5 57.5 42.0 25.3 66.9 49.7 64.0 63.0 20.7 30.8 25.1 27.9 76.7 54.6 18.3 19.8 19.0 35.0 16.8 94.1 20.5 21.7 27.1 46.2 49.9 31.7 51.9 63.6 24.1 41.6 54.7 46.2 26.0 20.6 50.9 55.0 45.4 65.6 105.0 27.4 36.3 24.1 47.4 42.0 57.8 49.5 55.7 39.6 143.1 93.3 65.0 71.1 26.3 36.0 47.8 72.6 27.3 50.1 81.1 42.4 75.9 44.4 26.8 39.8 46.6 20.7 47.8 47.8 69.1 398.1 24.3 55.8 136.0 79.2 36.2 28.5 22.4 25.0 25.7 43.7 20.3 104.2 112.2 91.2 26.2 59.5 44.8 51.1 31.3 32.1 58.3 27.9 20.7 251.1 65.4 60.6 35.0 37.7 71.1 64.8 79.9 27.9 22.1 21.6 33.8 19.4 48.9 7.1 28.3 8.9 14.6 6.9 5.3 12.7 10.8 10.9 5.9 355.0 10.0 33.3 18.9 12.5 11.5 42.6 63.3 75.4 60.7 49.5 57.5 64.0 63.0 54.6 46.2 63.6 50.9 430.3 41.7 18.6 55.8 69.4 29.3 23.5 22.5 37.0 31.5 86.5 37.8 17.6 15.7 28.9 27.6 18.8 10.8 77.5 20.3 99.7 18.0 242.6 114.8 46.7 205.9 19.7 86.5 33.0 20.7 10.8 34.0 35.2 240.5 34.7 104.3 286.3 11.1 51.6 37.0 54.6 14.0 61.1 127.2 48.1 740.3 26.4 115.1 35.6 62.8 76.1 31.4 34.0 23.1 44.4 41.8 15.2 17.3 269.1 39.5 9.6 24.8 69.5 17.2 39.5 36.4 36.3 45.1 42.5 25.1 30.4 13.3 51.6 64.3 11.5 39.1 SEC14L5 "KIAA0420, PRELID4B" ENSG00000103184 "SEC14 like lipid binding 5" O43304 16 4958330-5019157 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 78.7" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 85.5;Excitatory neurons: 67.0;Oligodendrocytes: 189.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.5;RPMI-8226: 1.6;SCLC-21H: 2.5;T-47d: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041492, HPA041825" Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "HPA041492: AB_10794519, HPA041825: AB_10794526" "unprognostic (1.90e-3)" "unprognostic (4.08e-2)" "unprognostic (5.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (5.68e-2)" "unprognostic (7.33e-3)" "unprognostic (8.71e-4)" "unprognostic (6.87e-2)" "unprognostic (1.56e-4)" "unprognostic (1.01e-3)" "unprognostic (7.12e-2)" "unprognostic (1.07e-1)" "unprognostic (5.61e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" 0.4 0.5 12.5 0.3 43.6 0.4 0.3 25.9 29.8 0.9 0.0 0.5 0.3 0.1 0.2 0.6 0.7 0.2 5.1 15.4 17.8 0.2 0.1 0.2 0.3 33.4 35.9 0.4 0.6 0.0 2.2 0.3 29.9 0.4 0.6 3.9 0.6 0.2 5.6 1.0 0.2 0.1 22.9 0.3 1.4 0.4 31.5 0.4 0.1 10.9 0.5 0.2 0.4 78.7 0.0 0.1 0.1 0.1 0.2 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.3 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.1 0.0 0.1 1.6 0.0 0.0 2.5 0.0 0.1 0.1 0.1 0.2 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 12.5 43.6 25.9 29.8 15.4 17.8 33.4 35.9 29.9 22.9 31.5 78.7 0.2 0.0 0.0 2.3 0.0 0.3 0.1 0.0 0.0 4.1 0.2 0.1 9.1 1.5 0.1 0.0 85.5 1.1 1.3 0.3 0.0 0.1 1.6 1.0 0.1 0.3 0.0 0.0 67.0 0.2 0.1 0.6 0.0 0.1 0.0 1.5 0.4 0.3 0.3 5.0 7.1 0.6 4.1 0.0 0.3 0.5 0.3 2.0 0.0 1.9 0.5 0.0 0.0 3.5 189.4 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.5 1.9 0.0 0.7 0.2 0.1 0.3 0.0 0.1 0.3 0.0 0.1 0.6 0.0 SEC16A "KIAA0310, p250, Sec16L" ENSG00000148396 "SEC16 homolog A, endoplasmic reticulum export factor" O15027 9 136440096-136483759 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005684 Supported Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 48000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "Endoplasmic reticulum" "HPA005684: AB_1079189" "unprognostic (1.24e-3)" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.30e-6)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.84e-2)" "unprognostic (3.48e-1)" "unprognostic (5.30e-2)" "unprognostic (1.38e-3)" "unprognostic (4.75e-1)" "prognostic favorable (4.47e-4)" "unprognostic (5.57e-3)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (1.41e-1)" 16.8 18.2 6.4 16.6 6.7 35.3 17.1 8.0 9.4 16.6 19.3 17.3 14.9 17.9 9.0 17.9 16.4 12.4 14.5 7.0 5.2 14.3 37.9 19.4 16.9 4.4 4.9 16.2 29.2 14.0 24.3 10.8 3.5 18.7 10.5 9.2 25.8 13.1 23.5 19.7 19.1 10.7 2.4 20.7 27.2 17.6 5.2 17.4 15.3 11.9 12.3 15.9 14.5 5.0 26.5 57.7 28.5 47.2 29.6 30.3 33.6 32.1 27.9 23.4 17.8 41.9 22.1 26.4 22.1 39.2 28.8 71.3 31.8 46.2 12.7 56.2 20.7 26.9 55.1 33.7 28.6 46.2 45.8 32.8 32.5 32.7 38.1 18.9 32.2 34.5 34.1 35.6 25.0 114.3 31.2 24.9 25.1 79.0 40.4 44.3 35.2 45.0 23.8 35.0 40.0 26.6 41.6 62.2 19.8 13.8 63.6 35.9 47.0 37.6 28.1 30.8 25.2 16.9 27.7 33.4 29.2 20.6 38.3 1.7 2.8 1.2 2.5 3.1 2.7 2.3 2.6 3.0 1.6 1.4 1.6 2.8 2.0 1.5 3.4 2.6 1.9 2.4 6.4 6.7 8.0 9.4 7.0 5.2 4.4 4.9 3.5 2.4 5.2 5.0 20.0 25.6 41.7 16.6 16.4 24.9 15.3 18.4 10.8 20.2 38.7 30.6 11.5 12.8 23.6 12.9 25.0 8.1 17.5 30.1 7.9 14.2 5.1 26.9 19.5 18.2 40.7 12.0 27.4 16.4 11.8 16.0 46.9 38.2 23.5 25.4 17.9 62.2 16.5 33.7 19.2 65.5 20.3 23.4 19.5 6.0 13.1 22.3 14.2 17.8 19.5 13.0 11.3 9.5 14.7 22.8 14.7 16.6 25.1 26.3 22.3 10.1 34.7 17.1 13.1 20.5 16.6 24.4 16.1 17.2 26.9 15.1 17.8 15.8 22.8 22.1 SEL1L3 KIAA0746 ENSG00000091490 "SEL1L family member 3" Q68CR1 4 25747433-25863760 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 128.3" "Cell type enhanced" "Detected in many" "B-cells: 114.7;Oligodendrocyte precursor cells: 128.7;Plasma cells: 271.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 82.1" "Group enriched" "Detected in many" 4 "memory B-cell: 42.0;naive B-cell: 41.8;plasmacytoid DC: 38.2" "Group enriched" "Detected in many" 4 "B-cells: 42.0;dendritic cells: 38.2" "Cell line enhanced" "Detected in many" "Daudi: 287.9;OE19: 217.9;U-698: 187.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 100.4" "HPA040045, HPA058792" Approved Enhanced Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA040045: AB_10796116, HPA058792: AB_2683822" "unprognostic (1.01e-2)" "unprognostic (2.03e-1)" "unprognostic (3.06e-3)" "unprognostic (1.44e-2)" "unprognostic (2.43e-3)" "unprognostic (1.80e-1)" "unprognostic (1.26e-2)" "unprognostic (1.39e-1)" "unprognostic (5.33e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (5.11e-1)" "unprognostic (4.77e-2)" "unprognostic (7.21e-3)" "unprognostic (1.32e-1)" "unprognostic (2.28e-2)" "prognostic favorable (4.33e-4)" 9.3 5.5 8.7 61.5 11.3 13.6 9.3 82.1 11.1 54.0 8.7 72.1 82.0 7.9 68.8 8.7 11.0 53.6 5.3 12.5 4.2 14.5 11.6 40.7 124.8 2.8 5.2 5.6 48.5 45.5 3.7 37.5 4.7 18.9 68.8 35.2 38.3 4.0 2.9 2.9 72.4 7.8 2.9 63.2 104.8 6.6 8.2 18.7 10.9 2.8 128.3 42.4 2.2 5.9 21.5 23.0 16.7 5.6 2.7 3.3 2.6 10.4 28.3 7.9 25.2 14.6 97.0 287.9 48.9 72.0 66.7 13.3 12.4 45.1 10.6 15.7 7.2 3.3 35.4 19.6 70.0 40.1 2.0 5.7 35.8 27.8 10.9 31.3 105.7 5.8 19.3 0.3 5.6 16.2 0.1 2.8 48.2 217.9 20.1 1.5 91.3 40.6 60.9 71.2 41.0 8.0 69.2 1.0 7.1 23.0 3.3 49.0 46.6 0.5 32.6 0.6 30.6 1.8 0.5 187.9 125.0 16.7 19.3 0.9 0.2 0.0 5.7 0.0 6.8 42.0 7.0 6.4 1.4 41.8 3.0 4.8 0.7 8.0 0.3 38.2 9.6 3.3 8.7 11.3 82.1 11.1 12.5 4.2 2.8 5.2 4.7 2.9 8.2 5.9 13.2 12.8 36.0 57.1 114.7 0.9 3.4 16.8 1.2 4.0 1.6 0.9 1.8 61.5 51.9 3.7 0.0 30.7 71.0 46.3 0.0 64.9 60.8 6.0 1.5 11.5 11.5 10.5 40.1 33.2 1.3 2.5 71.9 19.3 2.5 3.4 13.6 4.2 4.9 0.0 26.6 92.6 22.4 23.1 4.6 78.3 1.5 14.4 8.8 4.7 14.6 33.2 10.3 128.7 1.4 38.3 22.6 0.4 271.7 13.6 46.9 10.7 24.2 32.8 0.0 0.8 4.7 0.7 2.5 0.7 1.6 16.4 27.8 0.2 36.8 6.1 SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 14.7;Endothelial cells: 51.8;Hepatic stellate cells: 33.9;Macrophages: 10.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 8.3;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.3;T-cells: 8.8" "Group enriched" "Detected in some" 38 "EFO-21: 36.0;HEL: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" 11.3 2.3 0.2 11.9 0.6 2.2 10.6 0.0 0.6 8.9 3.7 3.3 5.1 6.4 4.1 5.1 6.7 9.5 6.7 0.3 0.0 5.6 2.5 12.6 7.0 0.2 0.2 1.8 1.2 3.1 2.2 6.3 0.2 6.1 4.1 0.0 2.7 5.7 1.0 3.6 4.8 14.2 0.1 1.0 2.8 0.7 0.7 2.6 4.0 1.8 12.6 14.4 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.4 0.6 0.0 0.2 0.0 1.1 0.5 0.2 0.0 0.1 0.2 0.1 2.1 0.3 0.0 0.1 8.8 7.8 0.2 0.6 0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.1 0.7 0.2 14.7 0.0 3.6 0.3 0.4 3.7 0.1 0.0 0.6 0.0 0.2 0.1 1.9 1.5 0.0 1.8 0.0 2.6 0.1 0.0 0.0 0.0 2.0 0.1 0.1 51.8 0.0 5.2 0.5 0.2 0.0 1.5 0.0 0.0 0.0 0.0 33.9 0.4 0.2 0.0 0.2 0.0 0.0 1.5 3.6 0.1 0.3 10.1 3.6 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.1 3.4 4.1 0.5 0.0 0.0 0.3 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEMA6B "SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Adipocytes: 43.6;Alveolar cells type 1: 28.9;Alveolar cells type 2: 44.6;Endothelial cells: 40.1;Excitatory neurons: 30.6;granulocytes: 29.7;Hepatic stellate cells: 37.5;Inhibitory neurons: 30.3;Macrophages: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 124.5;HMC-1: 198.1;HUVEC TERT2: 83.8;TIME: 107.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 1100000 "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB025157: , HPA055778: AB_2682916, HPA058523: AB_2683741" "unprognostic (4.03e-1)" "unprognostic (9.69e-3)" "unprognostic (6.38e-3)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (7.94e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (1.90e-1)" "unprognostic (4.21e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.26e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (9.55e-2)" 25.6 19.7 44.0 11.0 30.7 7.8 17.1 0.6 72.3 8.7 0.0 6.6 4.0 10.6 0.4 3.6 8.8 5.8 20.2 65.2 12.4 13.3 2.9 10.7 1.2 13.5 11.0 3.3 4.1 9.2 7.2 8.9 1.8 7.0 1.0 1.4 3.9 1.3 6.0 4.6 7.3 6.9 0.5 31.9 6.1 1.9 30.2 0.7 9.1 4.3 0.7 10.0 6.7 17.4 7.2 25.0 2.3 21.4 0.1 1.2 0.2 0.0 0.7 2.4 0.6 0.2 2.0 0.0 23.7 0.0 3.8 4.4 6.5 0.0 0.9 0.1 1.0 0.0 0.4 124.5 0.4 0.0 198.1 7.5 0.1 0.2 0.2 24.9 83.8 0.1 1.6 0.3 0.7 6.5 0.0 0.0 26.8 1.7 0.3 0.4 46.8 0.6 1.7 0.1 17.7 1.7 0.1 1.7 11.5 1.8 2.7 1.1 107.8 3.1 34.7 0.5 18.6 1.3 0.0 0.4 0.8 1.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 30.7 0.6 72.3 65.2 12.4 13.5 11.0 1.8 0.5 30.2 17.4 43.6 28.9 44.6 2.6 2.3 4.7 1.5 0.5 0.0 9.0 2.1 1.9 1.9 1.5 19.3 1.8 4.2 0.6 2.3 0.2 0.0 1.1 1.1 1.1 2.5 40.1 0.0 8.4 30.6 0.2 0.6 8.2 0.0 2.0 29.7 0.5 37.5 6.0 3.3 18.5 30.3 0.1 0.0 6.1 18.1 0.4 0.6 35.2 7.2 7.5 1.4 2.0 1.0 19.1 1.4 0.2 0.1 0.7 1.1 1.2 0.0 0.4 17.7 4.1 0.0 8.8 1.8 2.0 2.2 0.0 5.1 0.3 5.4 1.6 0.1 0.9 SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in some" "B-cells: 6.7;Cytotrophoblasts: 11.4;dendritic cells: 25.9;Fibroblasts: 4.9;Hofbauer cells: 9.2;Plasma cells: 10.2;Syncytiotrophoblasts: 4.9;T-cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 38.2;JURKAT: 48.5;MOLT-4: 66.3;REH: 39.0;U-266/70: 21.6;U-266/84: 33.4;U-698: 23.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" 1.6 0.9 1.0 3.6 1.1 0.7 1.1 1.2 1.9 1.9 1.0 3.4 4.1 1.4 0.7 2.0 2.0 0.3 0.8 1.0 1.1 1.4 1.9 2.6 15.3 1.0 1.0 1.6 0.8 0.5 0.7 0.3 1.1 1.7 0.0 0.1 3.2 0.8 0.2 1.3 16.7 0.7 1.0 35.9 4.4 0.2 1.4 16.0 1.9 0.6 6.6 2.0 1.6 1.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 38.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 7.3 3.0 0.0 0.0 0.3 0.0 5.1 1.2 0.2 0.1 0.1 0.0 0.7 0.0 48.5 0.3 16.7 0.0 0.0 66.3 1.4 0.0 0.0 0.7 39.0 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 21.6 33.4 23.2 0.6 7.0 0.0 118.4 2.5 102.2 319.3 2.3 245.1 170.1 286.7 292.4 9.6 179.4 264.6 268.7 8.5 230.4 1.6 270.6 329.6 272.6 1.0 1.1 1.2 1.9 1.0 1.1 1.0 1.0 1.1 1.0 1.4 1.0 1.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 11.4 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 4.9 6.1 0.0 0.0 0.0 SEPTIN11 "FLJ10849, SEPT11" ENSG00000138758 "Septin 11" Q9NVA2 4 76949751-77040384 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 90.1;Extravillous trophoblasts: 266.8;Fibroblasts: 40.1;Hofbauer cells: 52.0;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 495.8;fHDF/TERT166: 604.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Approved Approved Cytosol NA NA 2800000 "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (1.69e-1)" "unprognostic (2.93e-1)" "unprognostic (3.39e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.58e-2)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "prognostic favorable (2.40e-4)" "unprognostic (5.70e-3)" "unprognostic (6.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" 84.8 13.0 34.6 27.5 46.5 7.9 39.3 24.3 51.4 40.4 0.0 50.1 21.8 33.8 18.0 22.5 17.4 45.4 30.8 40.5 13.7 52.4 33.9 40.5 24.1 5.2 8.5 20.0 22.3 17.3 11.3 84.1 4.5 21.0 40.4 22.3 11.6 26.1 26.0 13.3 35.3 40.6 0.0 25.6 25.2 7.8 16.6 12.7 21.1 18.3 22.8 39.3 21.5 50.6 87.6 34.9 328.1 293.8 192.8 152.9 94.6 495.8 382.7 110.6 154.5 64.3 62.9 2.0 100.9 604.4 51.9 36.6 109.8 73.8 171.2 114.0 36.7 171.2 44.6 47.1 168.0 93.0 69.7 195.5 34.4 160.2 59.8 87.7 169.0 34.3 72.0 46.6 331.2 50.4 122.8 3.3 111.1 71.4 18.1 142.6 372.8 10.1 62.6 94.0 112.1 83.6 96.2 54.4 77.9 209.9 49.5 37.3 184.4 368.7 109.4 182.8 93.1 28.5 24.3 1.1 140.5 10.0 76.4 12.2 2.4 32.5 8.1 2.2 5.0 3.6 9.2 11.2 7.8 6.7 3.5 9.4 0.6 38.4 7.4 20.8 5.8 6.6 34.6 46.5 24.3 51.4 40.5 13.7 5.2 8.5 4.5 0.0 16.6 50.6 33.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 90.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 266.8 40.1 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 60.5 5.6 0.0 0.0 0.0 SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 235.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.3;Distal enterocytes: 530.1;Ductal cells: 735.4;Pancreatic endocrine cells: 457.4;Paneth cells: 465.1;Proximal enterocytes: 422.0;Syncytiotrophoblasts: 446.6;Urothelial cells: 432.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 305.6;HaCaT: 349.2;HBEC3-KT: 553.0;hTCEpi: 307.8;RT4: 381.9;SK-BR-3: 311.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA005974: AB_10603239" "unprognostic (1.41e-1)" "unprognostic (3.70e-3)" "unprognostic (8.78e-3)" "prognostic favorable (1.69e-7)" "unprognostic (6.78e-2)" "unprognostic (5.31e-2)" "prognostic unfavorable (2.11e-4)" "prognostic unfavorable (5.70e-4)" "unprognostic (3.12e-2)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (4.63e-3)" "unprognostic (2.67e-2)" 6.5 23.8 1.2 15.0 1.4 8.1 33.8 1.5 1.2 68.9 2.9 111.0 118.7 15.3 21.4 120.7 18.9 59.1 3.2 1.0 1.7 114.1 235.5 20.9 3.5 1.8 2.2 0.9 37.7 45.8 9.7 44.5 1.9 56.6 56.2 0.1 151.0 62.1 76.8 53.5 105.6 2.6 1.6 3.4 90.7 4.9 5.8 8.8 28.4 24.5 9.5 116.5 39.3 1.8 87.3 20.5 17.7 57.0 37.3 50.4 48.2 162.8 119.5 10.6 13.1 31.1 305.6 57.0 209.5 154.6 12.9 349.2 2.3 553.0 2.1 5.5 13.2 0.0 17.2 16.6 42.0 0.5 64.1 46.0 307.8 66.5 144.2 45.5 6.7 6.9 2.6 0.5 18.2 14.2 2.1 2.0 18.3 172.1 42.4 0.4 34.8 19.5 57.9 381.9 7.6 42.4 41.7 311.0 6.5 8.5 182.8 9.9 40.7 2.8 13.0 1.8 3.4 2.9 2.1 2.6 1.4 1.6 13.7 0.0 2.4 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 10.4 0.0 0.6 1.2 1.4 1.5 1.2 1.0 1.7 1.8 2.2 1.9 1.6 5.8 1.8 2.2 16.0 8.9 0.0 2.7 12.4 108.7 374.7 37.0 0.0 162.9 72.9 0.7 138.7 173.3 117.7 0.0 466.3 4.2 530.1 72.4 735.4 6.4 61.6 18.2 8.8 116.6 3.6 0.4 326.3 91.2 5.4 80.0 140.7 0.0 1.6 5.7 54.5 47.5 0.0 0.4 195.0 183.1 5.1 5.0 12.9 2.1 13.1 40.9 1.0 48.4 0.6 0.0 0.0 0.2 457.4 465.1 0.0 0.1 192.2 422.0 71.0 54.3 0.0 0.0 23.5 19.3 0.7 9.5 30.8 21.2 446.6 3.5 0.1 145.7 432.5 SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "liver: 346.9" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 259.1" "Cancer enriched" "Detected in some" 51 "liver cancer: 40.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 21.2" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 3960000000 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Cytosol "HPA048739: AB_2797237" "unprognostic (7.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.00e-4)" "unprognostic (6.11e-2)" "unprognostic (2.81e-4)" "unprognostic (2.31e-4)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (7.93e-3)" 0.4 0.4 0.4 0.6 0.7 3.3 0.6 3.2 1.4 0.6 0.4 0.7 0.7 0.7 0.5 0.4 0.3 0.5 0.6 0.4 0.4 0.5 346.9 0.4 0.8 1.5 0.5 0.9 0.5 0.2 0.2 0.5 0.8 0.4 0.7 3.1 0.4 0.4 0.5 1.7 0.7 0.6 0.4 0.7 0.7 0.6 0.7 1.3 0.7 0.4 0.4 0.2 0.1 2.5 0.6 0.2 1.8 0.7 0.7 0.6 0.4 0.5 0.5 0.9 0.8 2.7 0.6 2.1 0.3 0.4 0.2 0.4 2.2 0.5 1.3 0.8 1.4 2.0 0.8 21.2 0.4 1.6 1.1 0.6 0.5 0.3 0.7 1.1 1.0 1.1 0.5 1.3 1.0 0.3 1.4 0.8 0.8 0.2 0.6 0.9 1.2 0.9 0.5 0.7 0.9 0.8 0.4 0.4 0.2 1.0 0.9 0.9 0.6 0.7 0.4 0.7 0.6 1.1 0.5 0.9 0.9 1.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 3.2 1.4 0.4 0.4 1.5 0.5 0.8 0.4 0.7 2.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 2.8 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 6.6 8.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 3.3 259.1 0.0 0.0 0.0 0.4 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SERPINA11 ENSG00000186910 "Serpin family A member 11" Q86U17 14 94442464-94452800 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 92 "liver: 490.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 278.7" "Cancer enriched" "Detected in some" 9 "liver cancer: 94.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 17.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 230000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.50e-2)" "unprognostic (3.26e-1)" "unprognostic (9.00e-2)" "prognostic favorable (6.30e-4)" "unprognostic (7.44e-2)" "unprognostic (2.02e-2)" "unprognostic (1.70e-1)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 5.3 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 490.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 3.9 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.3 0.0 0.0 4.3 1.8 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 278.7 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.2 SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 9176.5;pancreas: 4910.2" "Cell type enhanced" "Detected in some" "Ductal cells: 20.9;Exocrine glandular cells: 33.0;Fibroblasts: 68.6;Late spermatids: 12.2;Pancreatic endocrine cells: 18.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "Hep G2: 449.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" NA NA 697000000000 94000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" 91.8 58.0 100.4 43.4 116.5 2.1 371.0 117.7 293.8 368.8 110.3 79.5 11.7 44.9 11.5 42.5 116.6 146.0 311.7 103.6 320.0 215.5 9176.5 169.9 5.0 196.3 183.1 181.5 4910.2 1.0 271.2 14.6 138.3 580.5 13.3 131.5 1505.8 54.9 177.8 55.7 91.6 83.1 141.4 31.7 290.5 66.9 176.3 2.6 72.6 38.9 6.4 207.4 70.4 173.0 0.2 0.5 0.0 0.3 0.2 0.8 0.3 0.1 0.1 0.0 0.0 1.2 4.9 0.6 4.5 0.0 3.3 0.9 0.0 4.4 0.0 2.7 0.0 1.0 0.2 449.9 56.9 1.9 0.7 52.0 63.9 0.0 2.5 5.4 0.0 0.0 0.3 0.2 0.0 17.1 0.5 0.5 0.8 1.6 0.0 0.6 2.2 0.2 3.8 0.2 0.1 0.0 1.8 2.5 65.6 0.4 2.4 0.0 0.6 0.0 8.5 0.1 19.4 1.1 2.0 2.1 0.4 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 116.5 117.7 293.8 103.6 320.0 196.3 183.1 138.3 141.4 176.3 173.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.5 1.8 0.0 5.6 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 20.9 3.7 0.2 0.1 0.3 0.0 0.0 0.0 33.0 0.0 68.6 9.7 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.3 0.0 0.0 1.0 0.2 0.0 0.0 0.0 18.7 0.0 0.4 0.3 0.5 0.0 0.1 1.5 0.0 0.0 1.7 0.8 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SGCG "A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE" ENSG00000102683 "Sarcoglycan gamma" Q13326 13 23180979-23325162 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 118.8;skeletal muscle: 158.0;tongue: 144.1" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 134.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 66.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA007476 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA007476: AB_1079946" "unprognostic (5.19e-2)" "unprognostic (8.28e-2)" "unprognostic (5.15e-3)" "unprognostic (1.64e-4)" "unprognostic (3.00e-3)" "unprognostic (3.61e-2)" "unprognostic (8.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.29e-1)" "unprognostic (4.49e-1)" "unprognostic (6.05e-2)" "unprognostic (2.23e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (2.98e-3)" "unprognostic (1.07e-1)" 14.3 0.6 0.0 0.1 0.1 0.0 2.2 0.0 1.9 0.4 0.0 1.1 0.1 0.1 8.0 3.3 1.1 0.8 118.8 0.1 0.0 0.3 0.0 4.8 0.0 0.3 0.0 0.2 0.1 2.1 0.3 0.0 0.2 3.2 0.6 0.3 4.3 0.4 158.0 3.4 0.6 0.1 0.0 0.1 0.9 1.5 0.2 0.1 0.1 144.1 0.1 3.0 1.4 0.4 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 66.6 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.2 0.0 0.2 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.3 0.0 0.2 0.0 0.2 0.4 0.2 0.0 0.0 0.3 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 1.3 0.0 0.0 12.5 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 1.6 0.0 0.0 0.0 3.4 3.0 7.5 0.2 5.4 1.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 1.2 3.8 13.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 SGK2 ENSG00000101049 "Serum/glucocorticoid regulated kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.5;kidney: 53.6;liver: 63.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.5;Distal tubular cells: 76.3;Hepatocytes: 32.8;Paneth cells: 21.7;Proximal enterocytes: 23.8;Proximal tubular cells: 25.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 20.5;CAPAN-2: 14.2;Hep G2: 18.7;OE19: 61.7;RPTEC TERT1: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA008859: AB_2668159, HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favorable (5.65e-4)" 23.5 1.4 4.9 1.5 14.8 0.5 6.1 12.6 10.5 3.5 0.7 37.7 31.6 1.8 33.8 1.0 3.7 10.0 1.2 6.0 7.7 53.6 63.2 1.0 0.2 18.1 13.3 6.6 16.2 0.5 3.0 0.8 14.3 2.6 40.5 5.6 1.8 2.9 0.4 6.2 20.1 1.6 11.8 1.1 22.8 1.8 13.3 0.3 1.7 0.4 0.3 4.2 3.0 24.5 0.0 20.5 0.3 0.1 0.3 0.0 0.1 0.2 0.0 0.2 0.0 0.6 14.2 0.1 8.7 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.4 0.0 18.7 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.1 0.1 0.5 0.1 61.7 0.0 0.1 0.1 0.0 25.4 4.2 0.2 1.0 0.0 1.2 0.1 0.4 0.0 0.1 0.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 14.8 12.6 10.5 6.0 7.7 18.1 13.3 14.3 11.8 13.3 24.5 0.3 0.0 0.0 4.9 0.2 0.1 0.1 0.2 0.0 0.8 0.3 0.8 4.9 8.6 0.0 11.0 0.0 5.1 0.0 76.5 76.3 6.8 0.3 0.9 0.5 0.6 1.8 0.0 0.7 6.3 1.3 0.4 11.2 2.4 0.0 0.7 0.7 32.8 0.7 6.7 1.3 4.1 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 3.5 20.7 2.5 21.7 0.4 0.0 0.1 23.8 25.5 0.2 0.8 0.0 0.2 0.4 0.1 0.1 0.0 0.1 17.1 0.2 0.0 7.7 0.3 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66712734-66862022 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 56.0;monocytes: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 28.4" "HPA006699, HPA027146" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favorable (5.52e-6)" "prognostic favorable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 5.2 5.3 13.4 9.8 25.7 8.5 24.1 21.3 16.9 10.5 36.0 10.3 8.9 8.0 8.6 7.6 6.9 7.5 5.4 14.6 17.3 14.7 13.6 10.0 7.8 29.4 21.6 9.1 15.6 28.3 6.2 5.7 28.3 7.4 10.3 2.4 7.0 7.1 2.9 13.3 11.3 5.3 19.3 8.9 7.5 9.4 20.9 5.8 17.5 3.5 6.9 5.0 5.7 49.0 14.2 3.7 0.6 2.4 3.9 6.5 7.7 8.1 7.4 4.2 5.1 6.1 8.6 10.2 2.2 7.7 13.6 4.9 7.3 5.5 5.4 5.3 11.7 9.7 2.6 6.7 4.1 8.9 10.5 2.9 3.7 1.7 7.9 4.3 7.4 7.4 1.5 4.6 10.0 2.4 6.2 5.8 1.9 8.5 5.0 11.7 5.3 7.6 6.4 3.3 2.9 2.2 3.4 6.5 14.4 6.0 28.4 16.9 9.0 4.4 3.9 3.9 3.4 6.1 12.8 12.7 4.5 14.2 4.9 21.1 15.0 5.1 8.7 9.9 13.8 4.7 8.8 8.0 13.8 6.4 8.7 7.1 2.0 7.2 5.1 8.9 5.7 9.0 13.4 25.7 21.3 16.9 14.6 17.3 29.4 21.6 28.3 19.3 20.9 49.0 20.7 6.4 28.1 0.0 12.5 13.3 8.1 3.3 8.6 1.7 56.0 30.5 7.6 7.2 8.5 11.0 18.8 9.2 24.9 13.3 15.6 7.0 0.9 16.7 6.6 15.3 16.2 10.3 0.0 18.2 1.4 8.9 6.6 12.3 15.2 11.0 17.5 20.7 22.9 0.0 0.0 9.3 8.2 41.9 14.3 2.2 4.1 42.6 8.8 0.0 53.4 3.8 19.6 0.0 0.0 14.8 8.4 7.9 18.3 9.3 14.0 36.8 15.4 1.7 0.0 5.9 4.2 5.9 13.7 9.9 15.8 4.8 19.4 5.2 10.4 5.3 SGSM2 "KIAA0397, RUTBC1" ENSG00000141258 "Small G protein signaling modulator 2" O43147 17 2337498-2381058 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 7.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021641, HPA024553" Approved Approved Nucleoplasm,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA021641: AB_2188702, HPA024553: AB_1856512" "unprognostic (1.06e-1)" "unprognostic (4.76e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-2)" "unprognostic (4.88e-2)" "prognostic favorable (3.11e-4)" "unprognostic (1.49e-1)" "unprognostic (7.84e-2)" "unprognostic (7.63e-2)" "unprognostic (1.90e-1)" "prognostic favorable (9.00e-6)" "unprognostic (2.78e-2)" "unprognostic (8.27e-2)" "unprognostic (1.80e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-1)" "unprognostic (3.07e-2)" 22.2 30.2 84.3 20.2 83.0 28.4 31.0 52.5 102.7 32.1 53.8 37.0 15.5 26.3 51.7 36.0 27.4 21.2 27.1 83.0 81.3 36.5 19.3 28.2 24.3 64.0 67.5 28.9 27.9 27.4 80.7 15.8 62.6 53.7 10.1 15.7 41.9 21.6 21.6 33.3 32.6 17.9 58.4 37.6 33.6 30.0 76.9 17.5 41.4 13.9 14.1 31.8 28.7 68.4 20.7 31.1 27.9 39.0 15.5 18.6 41.4 17.4 20.4 23.6 23.9 31.2 38.6 9.9 18.5 25.3 8.7 28.4 17.2 20.6 8.2 14.5 35.3 17.2 55.6 33.8 13.3 10.4 25.0 20.1 13.4 24.1 13.7 34.1 24.9 26.4 10.5 14.4 14.3 43.5 22.4 14.0 13.7 14.7 13.5 48.5 14.2 8.0 30.5 42.5 13.5 31.9 21.7 16.2 13.4 17.1 41.9 12.3 29.3 18.9 21.5 28.1 23.4 11.8 1.9 9.5 16.4 13.6 17.0 7.0 0.3 1.3 0.9 0.1 0.8 0.1 0.3 0.5 0.4 0.3 1.1 0.6 0.1 0.9 0.0 0.5 0.6 0.4 84.3 83.0 52.5 102.7 83.0 81.3 64.0 67.5 62.6 58.4 76.9 68.4 9.4 6.4 24.7 52.9 5.4 6.8 8.3 13.8 5.7 59.6 31.9 24.0 15.6 11.5 23.5 12.9 135.5 13.8 9.3 7.1 0.0 6.7 18.2 9.9 11.0 11.8 13.8 5.7 39.7 4.5 8.8 10.0 14.3 14.7 20.3 18.1 14.3 8.3 7.8 30.3 38.2 9.9 16.2 7.6 9.9 38.1 8.1 9.2 5.4 16.9 6.3 11.9 7.2 22.6 10.3 6.4 4.5 12.0 4.6 15.0 7.0 4.0 16.5 51.2 19.7 9.6 11.0 4.1 6.7 11.9 7.7 14.1 11.6 15.2 8.2 13.5 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 22.2 10.9 10.2 21.9 6.8 60.7 13.3 3.5 9.3 8.6 8.5 11.4 8.1 8.5 3.3 7.7 8.1 18.6 23.4 5.8 6.5 14.3 17.4 20.5 21.0 12.0 7.3 5.5 10.2 5.8 8.0 24.4 10.0 7.3 13.5 3.7 5.3 5.9 9.6 4.1 12.5 13.6 10.1 37.1 7.1 9.5 12.1 10.5 11.1 9.5 15.8 15.7 6.0 14.7 9.2 5.5 7.0 7.3 23.9 35.5 4.8 29.2 79.5 21.9 23.3 8.4 5.2 15.6 20.3 44.6 73.6 1.7 5.5 16.9 35.2 13.3 2.7 53.2 2.6 6.2 23.3 23.5 122.2 21.2 3.8 140.7 12.7 48.4 119.1 12.8 38.9 6.1 80.2 3.2 9.7 46.7 11.0 2.4 21.0 9.5 15.9 10.2 10.5 3.7 4.6 4.9 5.4 0.6 42.2 6.2 3.5 33.4 93.0 20.0 11.3 17.4 48.1 13.9 15.8 17.6 211.6 16.6 165.3 0.9 3.5 1.2 1.2 8.4 1.0 1.5 1.1 1.3 4.8 0.5 0.7 1.0 3.0 1.8 6.6 4.9 0.4 1.8 10.2 6.8 3.5 9.3 5.8 6.5 12.0 7.3 10.0 10.1 12.1 14.7 26.8 3.2 22.0 2.6 26.2 6.8 1.5 4.2 1.2 4.6 4.3 3.8 17.5 4.3 4.3 1.8 2.1 0.4 40.6 15.0 1.9 3.6 13.1 1.0 2.2 39.2 3.5 11.2 11.0 9.0 1.4 8.1 0.5 1.2 38.6 0.8 46.1 11.1 40.4 3.3 7.3 3.0 6.1 113.6 130.9 5.3 2.8 84.1 16.0 38.4 67.1 1.1 18.6 11.1 9.0 7.2 5.9 4.1 4.9 3.0 0.8 1.5 3.5 3.4 0.0 4.0 12.7 12.5 4.5 0.7 4.1 1.0 12.1 4.4 3.2 1.2 SH2D1A "DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD" ENSG00000183918 "SH2 domain containing 1A" O60880 X 124227868-124373197 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "lymphoid tissue: 262.5" "Group enriched" "Detected in some" 7 "dendritic cells: 77.6;NK-cells: 138.0;T-cells: 108.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 54 "gdT-cell: 120.2;MAIT T-cell: 162.9;memory CD4 T-cell: 90.4;memory CD8 T-cell: 175.8;naive CD4 T-cell: 91.2;naive CD8 T-cell: 108.3;NK-cell: 162.2;T-reg: 125.3" "Group enriched" "Detected in many" 70 "NK-cells: 162.2;T-cells: 175.8" "Group enriched" "Detected in some" 6 "HDLM-2: 101.1;JURKAT: 193.0;Karpas-707: 201.3;MOLT-4: 257.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072265 Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA072265: " "prognostic favorable (2.03e-4)" "unprognostic (1.18e-3)" "unprognostic (4.35e-3)" "unprognostic (9.66e-5)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (9.25e-3)" "unprognostic (3.34e-2)" "unprognostic (1.88e-2)" "unprognostic (2.80e-3)" "unprognostic (9.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.94e-6)" "unprognostic (1.27e-1)" "unprognostic (9.00e-2)" "unprognostic (2.36e-1)" "unprognostic (3.14e-3)" 1.4 1.1 0.0 10.8 0.1 5.4 1.2 0.1 0.2 0.9 0.1 1.6 1.5 0.6 0.6 1.1 0.5 4.1 0.3 0.1 0.1 0.4 2.8 3.2 38.4 0.2 0.1 0.4 0.2 0.2 0.2 0.3 0.1 1.1 1.5 0.0 1.3 0.3 0.3 0.4 2.5 0.6 0.2 14.7 2.7 0.2 0.1 262.5 0.7 1.2 16.6 5.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 101.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 193.0 0.0 201.3 0.0 0.0 257.2 4.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 32.7 33.3 0.0 0.2 0.0 0.0 1.4 0.6 0.1 120.2 0.5 162.9 1.1 90.4 175.8 0.5 0.2 91.2 108.3 2.4 162.2 1.2 0.8 125.3 91.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 1.1 3.2 4.7 0.0 3.0 1.5 0.1 0.0 0.0 0.0 0.7 0.8 0.2 1.5 0.0 0.0 0.0 0.1 77.6 0.0 0.0 0.0 0.0 0.5 0.2 0.7 0.0 7.4 0.1 0.0 0.0 2.0 1.1 0.2 3.8 0.0 3.6 0.9 0.1 0.0 0.0 0.0 0.0 5.6 4.4 0.0 0.0 4.3 5.4 0.0 2.3 0.0 138.0 0.5 0.2 0.0 0.0 0.0 14.1 0.2 0.0 0.5 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.2 1.0 0.1 108.9 0.0 0.0 0.0 SH2D2A "F2771, TSAd" ENSG00000027869 "SH2 domain containing 2A" Q9NP31 1 156806243-156816848 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.9;dendritic cells: 139.5;NK-cells: 113.3;T-cells: 103.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 30 "NK-cells: 28.5;T-cells: 66.5" "Cell line enhanced" "Detected in many" "HDLM-2: 46.5;HMC-1: 33.3;Karpas-707: 81.0;RPMI-8226: 24.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.5;hippocampal formation: 1.6" HPA074482 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA074482: " "prognostic favorable (4.96e-4)" "unprognostic (2.76e-2)" "unprognostic (7.50e-2)" "unprognostic (3.03e-3)" "unprognostic (1.14e-3)" "unprognostic (2.73e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (3.08e-1)" "unprognostic (1.64e-1)" "unprognostic (9.34e-3)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.26e-12)" "unprognostic (1.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.79e-1)" "prognostic favorable (1.31e-4)" 3.5 0.9 1.0 11.4 1.1 4.3 1.3 3.8 1.6 1.8 1.9 2.2 2.5 1.7 0.3 1.2 1.5 3.3 2.5 0.9 1.5 2.5 2.2 5.4 9.4 1.9 1.1 0.6 1.0 0.3 1.8 0.8 1.5 2.5 2.0 3.4 0.9 0.7 0.4 0.4 5.4 1.6 1.2 13.0 2.9 0.3 1.1 14.9 1.6 0.0 5.9 3.7 1.2 1.3 2.6 0.4 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 1.7 2.4 0.0 6.8 0.0 0.0 0.0 0.4 1.3 0.1 46.5 0.1 6.8 0.5 0.9 0.2 0.4 33.3 0.5 0.0 0.2 3.3 0.0 0.3 11.8 1.9 81.0 0.0 0.2 5.9 0.7 4.9 4.1 8.3 0.9 0.0 24.5 0.1 0.3 7.5 0.0 1.6 0.9 0.8 0.5 0.2 1.3 2.2 0.0 0.0 0.3 0.5 11.6 16.6 8.3 0.0 6.9 0.2 1.0 0.1 0.0 66.5 0.0 61.8 1.1 27.6 40.8 0.1 0.3 10.4 27.2 1.5 28.5 0.2 0.1 34.1 18.6 1.0 1.1 3.8 1.6 0.9 1.5 1.9 1.1 1.5 1.2 1.1 1.3 1.2 3.2 2.3 0.0 4.6 2.2 0.3 0.4 1.2 33.9 1.0 1.9 0.9 0.0 1.3 0.0 0.0 0.1 139.5 1.2 0.0 0.3 0.2 0.2 2.5 0.6 1.2 6.1 0.0 0.6 1.0 4.8 9.2 0.5 8.2 0.3 1.8 0.9 1.1 0.0 0.0 0.9 0.0 1.9 2.1 0.0 0.0 4.1 0.0 1.9 1.1 1.3 113.3 0.0 0.5 6.1 1.4 0.0 24.2 0.5 0.3 0.2 0.7 1.6 0.0 0.5 2.9 0.1 4.9 3.0 1.3 0.1 103.2 0.1 1.8 0.5 SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.6;dendritic cells: 29.7;Endothelial cells: 52.2;Hepatic stellate cells: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.3;HUVEC TERT2: 60.0;REH: 60.7;RPMI-8226: 46.1;TIME: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" 27.3 7.6 11.2 15.9 10.5 11.2 24.9 11.7 13.2 12.2 2.8 7.6 4.5 15.8 1.2 5.8 12.6 9.2 44.7 10.7 9.6 19.9 4.7 52.2 25.8 8.6 7.5 5.0 4.8 3.9 7.1 15.8 8.4 8.5 1.8 0.8 6.8 3.5 14.6 7.4 15.1 7.3 8.1 47.2 7.3 5.1 8.9 27.8 22.9 11.4 10.5 10.9 9.4 8.0 0.1 0.2 0.9 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 19.5 1.1 0.0 1.1 0.7 0.0 0.0 0.0 15.6 0.3 7.3 0.1 0.0 0.3 5.6 53.3 0.3 0.2 0.3 0.1 0.0 60.0 11.6 0.2 20.6 0.0 0.1 5.1 16.8 0.8 0.0 0.0 60.7 0.9 46.1 0.0 0.0 14.5 4.4 0.3 0.1 0.0 1.4 0.1 9.6 50.1 0.0 1.2 0.1 0.1 20.3 22.2 20.3 0.4 4.8 0.0 34.0 29.9 37.8 32.3 94.7 26.4 26.2 18.8 30.4 32.8 29.5 16.6 17.5 82.2 34.6 124.8 59.8 21.6 34.2 11.2 10.5 11.7 13.2 10.7 9.6 8.6 7.5 8.4 8.1 8.9 8.0 52.6 3.2 5.8 0.7 15.9 1.3 0.3 1.9 0.6 3.2 1.1 1.7 10.5 2.8 0.9 0.0 0.0 0.3 29.7 0.0 0.0 0.5 13.8 2.2 2.8 52.2 4.2 3.6 10.8 0.0 0.2 3.1 2.0 0.8 11.4 0.0 41.7 0.7 6.0 3.3 10.7 0.3 0.0 6.0 3.7 16.3 1.2 10.7 1.8 23.4 13.4 3.6 21.6 3.0 0.7 0.1 0.0 0.7 7.6 0.1 0.0 0.1 0.8 2.4 6.6 1.2 12.5 1.8 1.5 0.9 0.4 0.7 15.5 2.0 0.1 0.2 SH3BGR 21-GARP ENSG00000185437 "SH3 domain binding glutamate rich protein" P55822 21 39445855-39515506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 1268.3;tongue: 578.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.2;Distal tubular cells: 46.9;Early spermatids: 151.2" "Cancer enhanced" "Detected in all" "glioma: 21.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 101.0" "Low region specificity" "Detected in all" CAB003685 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "CAB003685: AB_425682" "unprognostic (3.41e-2)" "unprognostic (1.26e-1)" "unprognostic (5.84e-3)" "unprognostic (1.68e-3)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (3.89e-2)" "unprognostic (9.78e-2)" "unprognostic (2.06e-1)" "unprognostic (6.97e-3)" "unprognostic (3.59e-2)" "unprognostic (4.75e-1)" "unprognostic (5.98e-3)" "unprognostic (7.16e-2)" "unprognostic (4.60e-2)" "unprognostic (1.68e-2)" "unprognostic (2.06e-2)" 8.9 24.0 41.8 3.6 44.9 2.0 11.2 42.0 72.4 10.8 37.3 39.4 6.6 12.3 28.5 20.3 8.1 9.5 154.1 43.7 43.0 13.2 11.8 5.4 2.0 43.8 40.8 6.0 11.0 10.7 25.6 2.1 44.4 25.1 7.0 14.7 14.2 21.2 1268.3 4.8 8.5 11.0 41.0 3.3 16.9 20.1 42.4 3.2 16.3 578.1 2.1 20.8 8.1 50.5 2.0 2.9 3.7 4.2 5.5 9.2 1.0 2.7 0.6 1.9 1.5 1.6 3.9 6.6 8.9 10.9 14.5 0.3 1.2 3.1 2.9 3.9 7.6 7.6 0.9 3.1 15.1 2.8 1.3 7.6 13.5 7.0 12.1 3.4 1.8 13.9 5.0 7.7 7.8 9.4 3.7 4.2 3.2 6.2 6.2 6.5 13.1 4.5 8.3 1.8 10.0 4.0 5.8 4.9 5.4 2.3 19.8 0.5 1.6 5.0 0.6 3.1 7.9 26.3 5.7 6.7 101.0 5.0 6.9 0.0 0.2 0.0 0.2 0.9 0.9 1.4 0.4 0.9 0.9 0.6 1.6 1.2 0.2 1.2 0.9 3.7 0.1 0.4 41.8 44.9 42.0 72.4 43.7 43.0 43.8 40.8 44.4 41.0 42.4 50.5 2.4 3.2 3.9 15.3 1.4 2.7 12.8 5.9 1.8 2.1 11.4 25.0 180.2 5.7 4.4 5.5 4.2 3.7 3.2 2.3 46.9 5.1 151.2 11.3 5.0 3.1 1.2 0.8 6.4 21.3 1.7 5.6 3.6 10.6 4.5 5.3 2.2 9.2 2.4 5.0 6.5 1.7 4.1 1.6 2.0 35.4 2.1 1.5 12.4 5.6 1.2 21.2 0.0 3.0 14.6 4.8 3.2 5.7 1.0 3.3 2.3 14.4 6.7 6.2 6.6 22.7 16.9 32.4 23.6 1.1 1.7 1.9 1.4 4.7 2.7 4.6 SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.9;thyroid gland: 27.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.3;Late spermatids: 53.6;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 14.4;HaCaT: 21.1;hTERT-RPE1: 21.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042212: AB_10961180, HPA042456: AB_10959746, HPA066168: AB_2685627" "prognostic favorable (2.60e-4)" "unprognostic (8.35e-3)" "unprognostic (3.86e-3)" "unprognostic (9.01e-2)" "unprognostic (2.07e-3)" "unprognostic (7.32e-3)" "unprognostic (2.04e-4)" "unprognostic (7.47e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-2)" "unprognostic (7.38e-3)" "prognostic unfavorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" "unprognostic (8.59e-2)" 1.1 0.7 2.4 2.5 1.1 1.3 10.8 0.2 6.8 4.4 0.0 3.4 14.0 2.2 1.4 6.9 1.2 2.0 2.0 0.8 0.0 8.8 0.8 3.9 2.0 1.1 0.2 3.5 0.5 0.3 1.7 3.1 1.0 6.7 3.7 3.2 13.4 1.4 0.8 17.4 20.9 1.1 0.0 2.2 2.0 6.8 0.8 0.7 27.8 0.3 3.0 1.3 7.2 0.2 11.2 0.3 2.0 2.2 0.5 1.3 14.4 6.1 0.9 2.8 1.3 7.1 4.3 2.2 5.5 1.6 0.3 21.1 1.4 3.3 2.1 0.9 2.1 2.1 4.8 5.3 1.1 1.2 3.2 0.9 3.0 1.9 1.4 21.7 1.0 4.3 0.4 2.6 1.6 7.3 1.4 1.1 1.2 2.6 2.4 2.3 0.3 1.2 3.7 1.8 4.4 2.1 1.1 11.0 3.4 10.3 0.7 0.3 3.2 1.6 1.2 4.3 1.0 3.3 1.0 2.2 3.9 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.4 1.1 0.2 6.8 0.8 0.0 1.1 0.2 1.0 0.0 0.8 0.2 1.1 0.0 2.0 0.3 1.7 3.1 1.7 3.0 1.8 6.9 6.2 4.3 1.4 0.0 1.9 5.5 0.0 2.9 1.9 15.3 1.9 0.6 14.2 2.5 2.0 1.6 0.0 0.0 1.6 0.4 2.2 1.9 4.6 7.7 1.3 2.6 1.1 0.3 7.7 11.8 1.2 2.9 2.0 6.1 7.7 53.6 1.2 5.0 3.6 0.0 2.2 1.2 1.0 0.0 0.2 4.3 5.8 2.6 2.9 2.6 14.9 1.1 2.3 1.2 0.0 0.7 2.1 2.6 1.2 2.4 3.1 5.7 1.3 3.2 1.6 1.3 SH3KBP1 CIN85 ENSG00000147010 "SH3 domain containing kinase binding protein 1" Q96B97 X 19533977-19887600 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.8;monocytes: 289.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003351, HPA003355, CAB021892" Enhanced Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB021892: , HPA003351: AB_1079956, HPA003355: AB_1079954" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (4.65e-3)" "unprognostic (1.62e-1)" "unprognostic (2.88e-2)" "unprognostic (6.47e-2)" "unprognostic (9.91e-2)" "unprognostic (9.75e-2)" "unprognostic (1.76e-3)" "unprognostic (5.96e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (4.00e-1)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (4.92e-2)" 45.1 11.0 17.1 45.5 16.8 68.6 26.6 14.2 20.3 18.2 47.3 37.1 13.7 10.6 11.3 8.5 11.9 21.2 24.4 16.4 20.8 13.5 15.6 26.0 68.1 19.9 22.9 8.7 6.9 14.4 11.9 32.5 20.3 6.7 35.3 5.1 10.4 7.4 13.0 24.0 18.4 14.8 18.5 37.0 18.9 5.7 26.0 55.0 20.5 32.4 68.7 17.7 11.2 27.1 52.5 54.3 8.4 19.4 41.6 80.0 44.2 46.4 67.4 23.3 37.2 37.2 105.6 97.4 47.6 67.5 67.0 5.9 19.8 18.4 37.3 32.3 13.4 21.2 13.6 30.1 27.2 134.0 160.2 47.4 18.0 48.5 141.9 64.6 35.4 67.6 8.0 114.2 59.7 23.5 80.4 135.4 14.8 63.1 71.2 49.1 82.0 9.1 27.1 10.6 6.0 6.2 43.2 5.6 65.3 53.8 5.4 155.2 113.6 40.6 34.9 52.2 51.9 165.6 119.0 86.0 86.5 109.4 183.5 49.2 104.7 171.1 180.2 77.7 140.4 55.4 174.2 187.8 132.6 50.3 143.3 142.5 210.0 76.5 96.9 148.4 224.1 195.9 17.1 16.8 14.2 20.3 16.4 20.8 19.9 22.9 20.3 18.5 26.0 27.1 40.3 16.0 54.4 5.5 75.6 12.0 3.5 7.5 5.2 5.1 5.4 6.2 78.1 11.5 25.0 9.2 16.7 26.2 174.3 207.8 1.9 8.3 0.7 6.3 28.5 26.5 50.8 23.3 72.3 18.9 39.3 56.9 23.4 8.3 96.6 5.9 27.8 17.6 55.8 8.4 126.3 34.4 10.2 87.4 102.1 1.9 52.8 113.0 33.8 108.7 289.2 0.1 175.1 87.0 145.9 48.0 153.3 38.4 63.5 3.5 26.4 40.3 20.1 2.8 59.2 12.1 72.2 24.3 22.7 1.9 10.9 22.6 138.7 26.7 59.4 7.7 SH3PXD2B "FLJ20831, KIAA1295" ENSG00000174705 "SH3 and PX domains 2B" A1X283 5 172325000-172454525 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 91.1;Leydig cells: 39.7;Oligodendrocytes: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 95.2;ASC TERT1: 79.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036471 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli fibrillar center" "HPA036471: AB_10670799" "unprognostic (3.32e-1)" "unprognostic (1.95e-2)" "unprognostic (4.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.84e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (5.38e-3)" "unprognostic (3.11e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.87e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (8.45e-4)" 22.6 25.4 9.2 11.2 12.8 0.1 19.0 12.9 11.5 36.4 9.6 14.0 2.3 32.6 5.4 10.5 17.9 18.9 7.4 9.8 10.7 2.4 2.9 17.6 3.5 14.5 12.8 18.4 9.8 6.6 5.0 8.9 16.0 12.8 5.6 3.6 18.3 13.9 3.5 19.8 11.5 23.2 10.1 6.5 13.1 6.3 13.7 4.2 8.0 3.4 3.4 18.3 18.1 15.4 1.0 14.3 52.3 34.6 95.2 79.9 44.3 8.6 29.7 5.4 10.7 4.0 1.3 0.1 11.5 33.4 16.7 8.1 18.7 9.8 5.3 0.8 3.5 0.1 13.3 2.9 30.6 0.0 36.5 51.5 15.1 22.4 6.4 5.2 37.9 3.8 0.1 0.2 24.1 3.1 0.1 4.6 20.1 8.1 3.3 17.3 8.5 5.1 5.7 1.5 4.6 29.2 6.0 3.8 10.7 16.5 1.4 2.1 40.9 33.4 13.2 20.7 3.8 0.0 0.0 0.2 22.6 2.2 27.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.8 12.9 11.5 9.8 10.7 14.5 12.8 16.0 10.1 13.7 15.4 11.3 0.0 1.1 91.1 0.4 10.1 3.2 13.9 8.6 0.6 6.2 6.5 1.8 5.7 12.0 0.0 0.0 4.5 0.2 1.3 0.0 9.9 0.9 5.5 30.8 6.4 2.4 0.0 5.0 16.0 31.0 29.8 6.1 13.4 0.0 5.8 3.3 1.8 3.1 1.7 11.2 2.1 18.3 28.4 9.4 2.0 39.7 13.6 14.2 13.1 1.3 6.3 0.0 25.1 63.0 21.8 1.0 27.1 0.0 6.9 0.2 1.9 3.8 0.3 13.1 6.0 10.5 0.8 4.2 4.7 8.1 2.2 0.5 22.3 2.7 5.7 SH3TC2 "CMT4C, KIAA1985" ENSG00000169247 "SH3 domain and tetratricopeptide repeats 2" Q8TF17 5 148923639-149063163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.6;retina: 3.9" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 270.4" "Cancer enhanced" "Detected in some" "melanoma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.6;HBEC3-KT: 2.2;RT4: 3.6;SK-MEL-30: 5.2;WM-115: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037683, HPA037684" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA037683: AB_2675608, HPA037684: AB_10672603" "unprognostic (6.30e-2)" "unprognostic (4.07e-2)" "unprognostic (4.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.70e-1)" "unprognostic (1.92e-2)" "unprognostic (2.49e-1)" "unprognostic (2.17e-4)" "unprognostic (2.18e-2)" "unprognostic (4.53e-1)" "unprognostic (6.21e-3)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (6.62e-2)" "unprognostic (1.40e-1)" 0.1 0.0 4.7 0.0 8.0 0.1 0.1 5.1 5.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 3.6 5.1 0.0 0.0 0.0 0.0 7.1 6.9 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.0 3.9 0.1 0.1 0.2 0.1 0.0 0.0 5.8 0.0 0.0 1.5 7.1 0.0 0.0 0.1 0.0 0.1 0.0 12.6 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.3 0.1 2.6 1.5 0.0 1.8 0.1 0.6 1.9 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 1.1 1.6 0.0 1.3 0.0 0.7 3.6 0.0 0.0 0.0 0.0 5.2 0.1 0.0 0.0 0.2 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.0 5.1 5.0 3.6 5.1 7.1 6.9 7.3 5.8 7.1 12.6 1.9 3.2 3.7 0.3 0.1 0.9 0.8 1.0 0.0 1.4 0.7 0.4 1.7 1.5 3.8 0.0 4.2 0.8 0.0 0.6 0.0 0.6 6.4 0.3 0.1 2.8 0.0 0.0 0.4 0.2 0.4 0.5 0.0 0.5 2.5 0.1 1.4 0.3 0.4 0.0 0.4 0.0 2.0 1.8 0.7 2.3 0.3 2.2 0.0 4.7 0.1 2.3 0.0 0.0 270.4 1.6 0.0 0.0 0.1 1.2 0.0 0.1 4.1 25.4 0.0 0.3 0.4 2.3 0.9 1.0 0.9 11.9 0.3 0.1 0.2 8.8 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHC3 "N-Shc, NSHC, SHCC" ENSG00000148082 "SHC adaptor protein 3" Q92529 9 89005771-89178818 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1" "Group enriched" "Detected in some" 10 "Excitatory neurons: 155.2;Inhibitory neurons: 179.2;Oligodendrocyte precursor cells: 333.8" "Cancer enriched" "Detected in some" 5 "glioma: 5.1" "Group enriched" "Detected in many" 9 "amygdala: 16.8;basal ganglia: 24.9;cerebral cortex: 28.1;hippocampal formation: 23.6;white matter: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 20.7;hTERT-RPE1: 22.6;RT4: 7.9;SH-SY5Y: 7.6;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031427, HPA046656, HPA072448" Uncertain Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA031427: AB_2673877, HPA046656: AB_2679740, HPA072448: AB_2686521" "unprognostic (6.22e-2)" "unprognostic (5.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (9.07e-4)" "unprognostic (2.70e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (3.09e-1)" "unprognostic (2.72e-3)" "unprognostic (7.39e-2)" "unprognostic (1.53e-7)" "unprognostic (8.33e-2)" "unprognostic (1.05e-1)" "unprognostic (9.01e-2)" "unprognostic (9.84e-4)" 1.0 9.0 16.8 0.2 24.9 0.0 1.7 0.0 28.1 5.8 0.0 1.4 0.4 1.7 0.9 1.0 1.7 1.8 1.1 23.6 0.0 1.4 0.2 4.6 0.2 0.0 0.0 0.2 4.0 2.7 1.1 0.2 0.0 1.0 0.7 2.3 5.0 0.6 0.3 1.8 0.7 1.0 0.0 0.1 0.8 0.3 2.3 0.0 0.6 0.6 0.2 1.4 2.9 11.4 1.4 0.4 20.7 0.0 4.5 1.4 0.0 1.5 4.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.0 3.1 0.0 2.1 0.0 22.6 5.5 0.1 0.0 0.0 0.0 0.2 0.0 1.3 2.7 0.3 0.3 0.3 0.0 4.5 4.5 7.9 2.8 7.6 0.5 0.0 0.0 0.2 0.0 0.4 3.2 0.8 0.1 1.3 0.1 0.0 0.0 0.0 11.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 24.9 0.0 28.1 23.6 0.0 0.0 0.0 0.0 0.0 2.3 11.4 0.3 0.0 21.0 17.6 0.0 0.1 0.3 0.1 1.2 7.6 1.1 1.0 1.1 0.0 0.7 0.0 0.0 0.1 0.2 0.0 1.9 0.1 1.1 0.4 1.8 0.5 0.0 0.0 155.2 0.9 0.1 4.4 0.0 0.2 0.0 0.3 0.0 0.0 0.2 3.3 179.2 0.0 0.0 0.0 1.1 1.6 1.5 0.3 1.8 15.0 0.0 7.2 0.0 333.8 9.6 0.1 0.0 3.8 0.0 0.0 0.1 0.6 0.9 0.6 0.0 0.9 0.9 0.3 0.6 0.7 0.6 0.4 0.3 0.8 0.0 0.8 SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.9;Alveolar cells type 2: 23.4;Endothelial cells: 64.4;Hepatic stellate cells: 85.3;Kupffer cells: 26.7;Late spermatids: 23.0;Microglial cells: 26.2;Spermatocytes: 30.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 49.1;TIME: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" 23.4 9.8 9.4 3.3 8.8 1.2 20.9 7.7 10.6 13.2 7.4 7.4 3.4 12.1 4.3 5.0 12.5 6.9 22.7 8.3 8.3 10.5 5.8 20.6 3.9 8.4 9.1 7.6 3.0 4.9 3.7 16.5 8.8 8.1 4.2 0.6 5.4 4.2 7.1 6.4 8.9 8.0 8.1 21.4 5.5 22.2 10.2 2.6 22.1 11.3 2.3 9.7 9.9 8.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 4.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 49.1 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.5 0.0 1.0 13.6 0.0 0.3 1.4 0.0 0.1 0.2 0.1 0.0 1.0 0.0 0.5 0.3 0.2 1.5 1.5 1.1 0.9 0.6 0.6 0.1 0.9 0.8 0.9 2.4 1.7 1.1 4.0 0.0 0.5 9.4 8.8 7.7 10.6 8.3 8.3 8.4 9.1 8.8 8.1 10.2 8.0 56.9 0.0 23.4 3.9 0.3 3.3 0.4 0.3 1.2 0.1 0.4 1.3 4.4 1.5 1.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 13.0 0.4 0.3 64.4 0.0 2.7 0.3 0.0 0.0 6.7 0.0 0.5 3.8 2.1 85.3 3.4 1.4 0.0 0.3 0.0 0.0 26.7 6.6 23.0 1.5 2.0 0.0 26.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 3.7 0.7 0.0 0.1 0.0 0.4 0.0 3.3 2.2 30.6 13.0 0.3 1.6 0.1 0.7 0.3 0.0 0.3 SHISA3 hShisa3 ENSG00000178343 "Shisa family member 3" A0PJX4 4 42397488-42402487 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.3;heart muscle: 15.5;kidney: 21.4" "Group enriched" "Detected in some" 7 "Distal tubular cells: 43.0;Fibroblasts: 19.4;Hepatic stellate cells: 55.0" "Cancer enhanced" "Detected in many" "lung cancer: 7.6;renal cancer: 7.8" "Group enriched" "Detected in all" 4 "midbrain: 13.3;thalamus: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AN3-CA: 219.6;PC-3: 130.4" "Region enriched" "Detected in many" 23 "olfactory bulb: 51.7" "Region enriched" "Detected in many" 8 "spinal cord: 21.4" HPA054754 Approved "Lipid droplets,Cytosol" NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Lipid droplets" "HPA054754: AB_2682593" "unprognostic (9.04e-3)" "unprognostic (3.47e-3)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" "unprognostic (1.26e-1)" "unprognostic (6.78e-3)" "unprognostic (1.26e-2)" "unprognostic (2.86e-1)" "unprognostic (3.04e-1)" "unprognostic (1.37e-3)" "unprognostic (3.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "unprognostic (5.32e-2)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.99e-3)" 4.1 1.8 1.8 1.8 1.6 0.0 2.3 1.1 1.6 0.7 1.2 6.2 2.2 0.2 0.3 1.7 0.5 1.0 15.5 1.0 2.2 21.4 0.6 5.7 7.0 1.7 13.3 0.3 0.2 0.2 0.6 0.0 2.6 0.8 3.0 0.1 0.6 1.0 1.6 0.5 10.4 4.3 1.4 0.4 2.9 0.6 10.1 0.1 5.0 1.4 0.8 3.5 1.3 1.2 0.0 0.0 0.0 219.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 23.7 0.1 0.0 0.0 23.3 0.0 0.0 0.0 2.6 0.0 0.1 0.0 6.6 0.0 0.8 0.4 0.0 0.0 0.0 0.0 5.2 0.3 0.0 0.0 0.0 0.0 1.2 0.0 10.1 0.0 130.4 0.2 0.0 0.0 9.0 0.0 0.1 0.3 0.0 0.0 0.0 8.1 0.1 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.6 1.1 1.6 1.0 2.2 1.7 13.3 2.6 1.4 10.1 1.2 4.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 3.7 0.0 0.0 0.1 0.1 43.0 0.0 0.0 0.1 2.5 3.7 0.0 5.3 0.0 0.0 0.0 19.4 0.5 0.1 0.0 1.1 55.0 0.2 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.0 3.4 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 2.4 0.0 0.1 0.0 0.2 1.4 0.5 0.4 0.1 0.0 0.0 0.0 2.4 0.1 0.0 SHISA4 "C1orf40, hShisa4, TMEM58" ENSG00000198892 "Shisa family member 4" Q96DD7 1 201888680-201892587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;skeletal muscle: 219.7" "Cell type enhanced" "Detected in many" "Muller glia cells: 37.5" "Cancer enhanced" "Detected in all" "glioma: 49.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 24.6;intermediate monocyte: 8.1;neutrophil: 9.1;non-classical monocyte: 10.2" "Group enriched" "Detected in many" 10 "granulocytes: 24.6;monocytes: 10.2" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 23.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061273, HPA067885" Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA061273: AB_2684460, HPA067885: " "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (1.48e-3)" "unprognostic (2.12e-3)" "unprognostic (6.59e-2)" "unprognostic (8.29e-3)" "unprognostic (7.06e-2)" "unprognostic (5.00e-2)" "unprognostic (2.32e-1)" "unprognostic (1.44e-1)" "unprognostic (8.29e-2)" "unprognostic (2.32e-2)" "unprognostic (1.63e-3)" "unprognostic (1.20e-1)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-1)" 6.7 26.9 64.6 2.0 71.6 0.5 5.9 61.5 59.4 9.2 27.3 7.7 0.4 10.9 3.5 2.7 6.9 3.6 48.6 55.5 53.3 6.4 3.2 5.2 0.8 63.9 64.9 10.7 5.1 3.9 9.2 2.3 58.0 8.5 0.9 4.7 15.7 4.0 219.7 3.6 3.5 3.7 59.1 2.8 6.7 5.7 68.4 0.3 11.4 58.3 0.6 8.6 6.4 57.1 1.3 10.5 1.6 7.8 12.7 7.7 1.3 9.1 19.3 5.2 6.5 2.0 4.1 0.0 10.6 12.6 17.2 3.4 0.1 1.4 3.0 1.3 0.6 0.1 2.8 1.3 8.2 0.1 6.7 7.6 4.3 6.5 3.0 23.2 8.0 0.1 0.2 0.7 8.1 1.3 0.0 0.0 0.8 0.9 11.3 0.4 0.0 2.1 5.0 4.1 0.5 6.6 3.3 1.6 10.9 7.6 4.4 1.0 7.5 6.3 5.5 3.9 4.4 2.4 2.9 0.1 9.2 0.0 11.2 0.0 1.7 24.6 1.7 8.1 0.8 0.0 0.3 0.4 0.9 0.0 0.0 0.3 9.1 0.0 10.2 0.0 0.0 0.7 64.6 71.6 61.5 59.4 55.5 53.3 63.9 64.9 58.0 59.1 68.4 57.1 12.8 0.0 1.7 14.4 0.3 14.1 4.5 7.4 6.8 11.7 8.2 14.4 20.9 8.6 3.7 11.0 4.2 2.0 0.9 0.1 33.2 24.9 0.7 2.4 10.0 11.1 1.8 0.0 8.4 15.4 27.2 19.2 3.6 2.7 1.3 10.4 12.5 12.1 3.2 5.0 6.5 0.1 6.1 6.9 25.1 2.3 15.8 3.7 23.2 1.0 4.6 37.5 0.0 17.6 19.2 9.5 0.0 29.3 0.2 7.4 0.0 6.3 1.3 3.8 19.7 9.2 18.0 1.4 0.8 0.9 6.8 2.7 1.5 2.3 0.1 2.1 SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 398.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 307.7;Proximal tubular cells: 435.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023314, HPA078682" Enhanced Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA023314: AB_1856830, HPA078682: " "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favorable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favorable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" 37.5 9.4 8.1 4.0 9.4 9.5 36.3 12.6 9.5 13.6 7.1 17.5 13.8 7.6 4.9 59.2 13.1 7.7 5.7 8.8 8.5 168.5 398.7 10.3 9.0 10.8 9.3 11.7 8.8 85.7 4.1 7.7 10.7 10.1 6.1 3.1 30.0 10.0 18.8 22.6 24.4 3.7 8.0 21.7 13.3 12.8 9.4 21.1 23.5 18.6 17.6 11.5 19.3 16.0 39.6 28.9 5.5 34.5 29.9 15.8 63.0 11.3 10.3 30.8 31.2 22.1 22.5 26.8 27.8 3.6 16.4 18.8 32.4 39.7 24.3 17.3 30.6 13.0 39.9 21.6 7.2 4.4 11.0 21.1 13.6 23.1 7.2 10.9 9.7 32.3 10.0 10.9 11.3 12.4 46.0 13.9 17.4 43.6 5.1 29.7 48.5 34.7 69.3 17.0 24.0 5.3 82.7 14.9 21.4 50.2 64.5 19.4 2.6 5.7 14.0 71.4 17.6 10.7 20.5 7.1 10.3 12.7 16.5 10.2 4.7 5.2 5.3 5.9 8.1 4.4 6.6 5.5 3.5 3.7 6.8 6.4 0.2 8.5 5.2 1.1 11.2 4.3 8.1 9.4 12.6 9.5 8.8 8.5 10.8 9.3 10.7 8.0 9.4 16.0 11.2 12.8 31.0 3.3 10.4 10.3 21.7 16.5 18.8 3.1 22.7 13.8 2.7 42.9 11.2 36.8 4.2 23.7 5.2 8.9 82.2 13.7 10.9 6.2 1.9 7.4 1.2 28.0 5.2 7.7 76.1 8.0 9.2 10.1 8.2 9.9 13.6 307.7 39.6 0.0 4.8 12.9 4.1 36.8 3.5 5.5 5.9 17.2 12.4 9.4 4.4 33.8 5.2 2.0 11.4 5.3 9.7 3.0 20.3 5.9 53.7 435.7 3.5 4.2 19.7 8.1 4.4 30.0 21.4 35.4 10.5 8.5 10.1 4.9 32.2 10.9 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 11 "Hofbauer cells: 78.6;Kupffer cells: 93.4;Macrophages: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Lineage enhanced" "Detected in single" "monocytes: 1.5" "Cell line enriched" "Detected in single" 19 "THP-1: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" NA NA 260000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" 23.0 13.7 2.0 7.7 2.9 12.3 8.6 1.9 6.5 1.8 7.5 10.2 5.1 2.0 1.8 2.2 7.0 8.5 6.4 1.8 2.2 3.9 8.4 16.7 12.7 10.2 3.3 2.7 1.6 0.5 2.3 18.8 10.9 1.9 6.6 0.3 5.4 1.2 3.7 3.0 11.2 7.7 5.0 18.9 5.1 2.5 10.9 3.6 3.7 2.6 1.9 7.6 3.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.0 2.9 1.9 6.5 1.8 2.2 10.2 3.3 10.9 5.0 10.9 3.9 0.5 3.2 4.4 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 0.3 2.4 0.0 0.6 0.0 2.1 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.3 0.0 0.0 93.4 6.3 0.1 0.0 42.6 0.0 3.7 2.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 1.4 1.0 0.0 0.1 0.6 0.6 1.9 0.4 0.0 0.0 0.0 SIGLEC11 ENSG00000161640 "Sialic acid binding Ig like lectin 11" Q96RL6 19 49948985-49961172 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 23.1;ovary: 65.5" "Group enriched" "Detected in some" 7 "Granulosa cells: 196.9;Theca cells: 192.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 6 "granulocytes: 1.4;monocytes: 1.3" "Cell line enriched" "Detected in single" 16 "HEL: 10.1" "HPA052132, HPA060278" Approved Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA052132: , HPA060278: AB_2684240" "unprognostic (1.07e-1)" "unprognostic (2.85e-3)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (3.35e-2)" "unprognostic (9.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.20e-1)" "unprognostic (8.79e-4)" "unprognostic (2.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.95e-3)" "unprognostic (5.38e-2)" 1.1 7.3 0.5 1.8 0.8 0.4 0.4 0.4 0.7 0.3 0.6 0.5 0.8 0.3 0.2 0.1 0.9 0.3 0.4 0.6 0.6 0.4 1.7 1.7 0.6 1.4 1.0 65.5 2.7 0.1 0.2 1.8 1.3 0.2 0.4 0.2 0.3 0.2 0.2 0.2 1.0 1.2 0.8 23.1 4.7 1.5 1.6 0.1 0.2 0.1 0.0 0.6 0.2 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 10.1 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.3 1.4 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.1 0.5 0.8 0.4 0.7 0.6 0.6 1.4 1.0 1.3 0.8 1.6 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 19.6 0.0 0.6 0.2 0.3 1.0 0.0 0.0 0.0 1.1 0.1 4.3 0.0 0.3 0.0 196.9 5.3 0.6 7.9 0.0 0.0 0.0 0.0 26.8 0.2 0.1 0.0 6.1 0.0 5.6 1.3 0.0 0.0 0.0 0.0 2.7 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 7.5 1.7 0.7 0.0 0.1 0.1 0.2 192.3 0.0 0.0 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 47.8;salivary gland: 51.1;skeletal muscle: 119.4;tongue: 46.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.7;Basal respiratory cells: 30.8;Club cells: 33.9;Ionocytes: 30.5;Prostatic glandular cells: 27.4;Respiratory ciliated cells: 67.1;Skeletal myocytes: 77.3;Spermatogonia: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 36.3;LHCN-M2: 142.2;RH-30: 71.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "CAB058690: AB_2665581, HPA001893: AB_1079991" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (5.09e-2)" "prognostic unfavorable (8.92e-6)" "unprognostic (1.33e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-3)" "prognostic favorable (3.94e-4)" "unprognostic (1.40e-1)" "unprognostic (9.15e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (3.06e-8)" "unprognostic (8.61e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" 5.5 0.4 0.3 0.0 0.5 0.0 1.9 0.5 1.2 15.2 1.0 0.0 0.0 0.0 0.4 1.1 0.8 0.5 0.0 0.3 0.3 0.0 0.0 1.5 0.5 0.3 0.4 0.2 0.3 47.8 19.8 0.0 0.4 13.2 0.0 0.0 51.1 0.2 119.4 0.3 0.0 0.0 0.3 0.0 0.4 1.7 0.5 9.7 1.9 46.3 0.2 1.6 0.8 0.4 15.2 3.5 0.6 28.1 17.0 20.6 0.4 4.1 10.6 4.9 4.0 0.0 8.2 0.0 2.2 0.6 2.1 4.4 10.3 6.4 2.1 0.0 17.1 2.0 1.9 6.8 0.0 0.0 0.2 15.6 4.9 2.3 0.7 36.3 0.3 1.6 5.8 0.0 142.2 2.8 0.0 0.5 0.0 0.0 8.9 0.0 71.9 0.0 5.9 16.3 2.5 0.3 5.0 0.3 6.1 0.5 3.3 0.4 13.9 6.7 5.4 7.9 6.5 0.5 0.1 0.0 1.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.2 0.3 0.3 0.3 0.4 0.4 0.3 0.5 0.4 0.8 3.2 1.5 0.0 0.0 0.1 30.7 30.8 0.6 0.0 1.0 0.8 0.9 0.0 33.9 1.8 0.0 0.2 0.0 0.1 1.9 0.0 0.2 1.1 0.1 1.6 0.0 0.0 0.0 0.8 0.4 5.7 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.5 0.0 0.0 0.6 0.0 0.3 0.0 1.9 0.0 0.8 0.0 1.0 0.1 0.2 0.0 1.2 0.0 27.4 0.0 0.1 67.1 0.2 0.0 77.3 5.1 0.0 25.0 0.1 0.1 0.3 0.1 0.1 0.0 18.3 SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "dendritic cells: 224.2;Hofbauer cells: 67.4;Kupffer cells: 199.4;Macrophages: 154.2;NK-cells: 109.2;Plasma cells: 83.0;T-cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 47.9;JURKAT: 201.5;Karpas-707: 129.2;MOLT-4: 35.8;U-266/84: 76.1;U-937: 55.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" 25.2 13.1 9.5 82.9 6.4 97.4 9.5 6.1 11.5 11.1 8.2 10.8 7.9 5.2 2.9 9.4 7.0 20.9 5.2 8.2 9.1 6.4 16.9 25.9 78.6 12.0 8.4 3.0 5.8 3.1 3.1 15.2 10.3 5.2 8.4 1.3 4.6 3.6 1.5 4.0 20.7 12.5 9.7 70.3 12.5 1.4 16.9 156.6 27.6 4.4 71.0 22.0 4.2 14.6 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 0.1 2.3 0.0 0.0 0.0 6.3 47.9 0.8 0.0 0.6 0.0 0.2 0.0 201.5 0.1 129.2 0.0 0.0 35.8 9.3 0.0 0.0 0.0 0.2 0.3 7.8 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.1 0.0 15.3 0.0 0.1 0.3 0.2 0.1 6.9 76.1 0.0 0.6 55.6 0.0 0.7 110.2 203.6 87.6 123.1 110.1 41.0 79.7 88.2 79.8 48.3 75.3 77.4 262.3 132.6 148.4 6.3 124.4 158.9 9.5 6.4 6.1 11.5 8.2 9.1 12.0 8.4 10.3 9.7 16.9 14.6 2.4 9.6 19.1 0.7 36.6 2.2 0.3 0.0 0.0 9.7 0.9 1.3 3.3 1.5 10.5 0.0 0.0 0.4 224.2 0.2 0.0 0.2 0.2 0.7 0.7 5.9 0.0 13.2 1.0 0.0 1.2 4.5 3.6 0.5 37.2 1.7 8.9 2.9 67.4 0.0 1.3 0.5 0.0 199.4 15.0 1.0 0.3 154.2 5.4 14.0 36.7 0.1 109.2 0.0 0.1 0.0 0.0 0.0 83.0 0.1 0.0 0.3 5.1 0.3 6.6 1.4 1.9 0.0 0.1 0.3 2.7 0.1 160.0 0.1 0.1 0.2 SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 97.0;Macrophages: 21.8;NK-cells: 44.3;Plasma cells: 25.8;T-cells: 59.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Group enriched" "Detected in some" 7 "HEL: 91.2;JURKAT: 51.8" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" 1.3 0.6 0.4 5.7 0.6 12.5 0.8 1.6 0.7 0.8 0.3 1.7 2.7 1.0 0.5 0.7 0.9 2.4 0.7 0.4 0.2 0.5 1.5 4.1 10.4 0.7 0.4 0.4 0.4 0.1 0.4 0.6 0.8 0.7 1.7 0.5 1.4 0.5 0.6 0.7 3.1 0.5 0.3 8.0 2.6 0.5 0.6 18.3 0.7 0.2 9.0 2.2 0.6 1.1 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 91.2 0.6 3.4 0.0 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 51.8 0.1 0.2 0.0 0.2 10.9 7.6 0.1 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.1 7.6 0.1 3.0 0.4 3.8 28.8 0.7 24.1 0.4 23.8 27.1 0.4 0.3 21.8 30.5 4.8 39.2 0.1 48.5 33.4 26.5 0.4 0.6 1.6 0.7 0.4 0.2 0.7 0.4 0.8 0.3 0.6 1.1 0.6 0.0 3.9 0.0 1.6 0.4 0.1 0.0 0.0 0.3 0.5 0.3 0.3 0.0 0.7 0.0 0.0 0.1 97.0 0.6 0.0 0.2 1.1 0.4 0.4 0.4 0.0 8.2 2.2 0.0 0.2 0.5 4.1 0.6 1.3 0.0 0.7 0.1 0.2 0.0 1.7 0.0 0.0 1.6 0.4 0.0 0.3 21.8 0.0 1.9 1.2 0.4 44.3 1.5 1.4 0.3 0.1 0.0 25.8 0.1 0.0 0.1 0.0 0.9 0.0 0.3 0.4 0.0 0.2 0.2 0.1 0.1 59.2 0.0 0.2 0.3 SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 61.7" "Cell type enhanced" "Detected in some" "B-cells: 23.6;dendritic cells: 19.7;Late spermatids: 22.1;NK-cells: 45.3;Plasma cells: 21.4;T-cells: 26.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Daudi: 88.2;U-698: 127.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" 1.7 1.1 0.2 20.6 0.2 3.2 2.2 0.8 0.4 2.0 0.3 3.8 2.7 1.3 1.4 2.1 1.3 4.6 1.0 0.2 0.1 0.9 4.0 4.4 61.7 0.3 0.1 1.2 0.9 0.2 0.2 1.8 0.3 1.3 3.5 0.1 2.2 0.5 0.4 0.6 13.8 1.4 0.1 32.2 5.5 1.2 0.4 19.3 1.7 0.5 48.6 5.7 1.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 6.7 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.8 0.1 0.0 0.0 21.8 1.3 0.1 0.7 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 14.2 127.4 0.0 0.6 0.0 11.2 0.3 23.1 56.1 1.0 38.9 36.2 35.6 71.4 0.3 35.4 19.5 39.5 2.5 41.3 3.1 1.0 45.6 22.2 0.2 0.2 0.8 0.4 0.2 0.1 0.3 0.1 0.3 0.1 0.4 0.3 0.1 0.0 1.3 0.0 23.6 0.4 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.1 9.4 0.1 0.1 0.3 0.0 3.2 0.0 0.2 0.0 0.4 0.5 0.1 1.3 0.0 3.3 1.1 1.1 0.0 0.0 0.0 0.0 4.3 0.8 22.1 0.0 1.1 0.0 0.0 1.6 0.0 45.3 0.0 0.0 0.1 0.1 0.0 21.4 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.3 0.0 26.1 0.0 0.0 0.0 SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 63.6;Syncytiotrophoblasts: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.6" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" 23.3 22.9 6.1 13.1 6.2 34.0 21.0 6.8 7.9 27.1 5.8 22.5 13.9 29.6 18.4 31.2 22.8 21.3 23.2 5.9 6.1 20.6 10.3 22.7 15.1 7.4 6.8 40.8 22.8 9.6 18.8 21.1 7.4 22.9 8.3 2.0 17.4 15.7 18.3 42.9 18.7 13.5 6.9 19.3 18.9 8.9 8.1 9.8 20.6 9.4 11.2 31.8 26.0 7.7 66.4 27.0 7.3 38.3 25.2 27.6 48.9 49.2 29.2 32.5 32.3 25.0 31.8 51.0 91.1 46.8 41.3 55.9 24.4 24.7 8.6 32.7 11.8 15.9 36.0 20.3 47.0 19.0 24.9 34.8 28.1 29.9 15.8 28.5 22.6 8.7 17.6 48.6 21.6 90.0 10.2 17.0 5.9 32.4 54.9 16.8 19.9 38.8 24.7 24.2 6.8 12.0 29.8 55.4 13.0 8.5 17.9 15.0 29.5 38.0 23.9 89.6 63.2 34.3 35.6 52.8 40.9 39.6 20.2 218.6 4.5 21.1 12.9 6.5 9.6 5.3 8.5 9.2 3.9 5.2 6.0 5.9 6.1 8.8 5.6 9.5 6.4 6.3 6.1 6.2 6.8 7.9 5.9 6.1 7.4 6.8 7.4 6.9 8.1 7.7 13.3 3.2 7.0 2.3 21.1 22.6 27.1 15.2 50.7 2.8 13.7 11.8 4.0 15.7 7.3 18.4 6.2 49.5 17.4 22.1 7.9 17.8 3.6 13.0 14.8 15.8 10.2 11.1 1.6 19.4 63.6 21.2 13.7 21.0 12.7 15.8 16.8 2.3 19.4 3.3 1.4 15.5 4.1 8.4 19.6 1.2 27.1 22.7 3.6 1.0 13.2 3.0 23.7 1.5 1.6 20.9 16.0 13.2 19.8 14.1 17.2 10.4 6.9 1.9 6.6 12.1 14.3 1.9 2.9 45.5 27.8 103.0 24.5 5.4 11.7 23.5 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SLC15A5 ENSG00000188991 "Solute carrier family 15 member 5" A6NIM6 12 16188485-16277685 "Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Astrocytes: 2.0;Early spermatids: 4.2;Excitatory neurons: 1.1;Late spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041638 Uncertain NA NA "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA041638: AB_2677590" "unprognostic (3.68e-3)" "unprognostic (1.64e-1)" "unprognostic (4.89e-6)" "unprognostic (1.34e-1)" "unprognostic (1.72e-3)" 0.2 0.0 0.4 0.0 0.4 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC16A7 MCT2 ENSG00000118596 "Solute carrier family 16 member 7" O60669 12 59596029-59789855 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 34.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Early spermatids: 117.3;Excitatory neurons: 150.5;Inhibitory neurons: 128.2;Late spermatids: 135.5" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 22.2" HPA005911 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA005911: AB_1853659" "unprognostic (1.52e-2)" "unprognostic (9.47e-3)" "unprognostic (9.48e-2)" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (1.29e-2)" "unprognostic (5.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-2)" "unprognostic (9.79e-2)" "prognostic favorable (8.85e-5)" "unprognostic (2.19e-3)" "unprognostic (3.11e-1)" "unprognostic (9.35e-2)" "unprognostic (2.45e-2)" 20.1 6.8 1.2 3.9 1.2 4.7 4.1 5.7 3.9 2.8 3.7 2.0 1.6 3.0 1.5 6.3 2.2 5.4 34.4 1.3 0.3 11.6 3.9 4.5 4.9 2.9 0.4 2.7 9.8 1.0 1.5 1.6 2.9 1.6 2.5 1.8 2.9 1.6 1.8 7.9 2.5 3.5 0.5 6.3 10.0 2.2 1.3 4.5 1.6 3.6 4.2 4.0 3.0 4.2 0.2 3.6 0.8 0.5 10.9 18.1 0.2 8.8 8.1 4.0 3.4 0.3 6.3 5.8 2.5 16.8 3.8 0.8 1.0 1.7 6.0 2.4 0.5 10.7 12.6 0.5 5.9 14.3 0.1 8.5 3.9 1.4 10.3 7.5 1.6 7.2 0.2 13.0 6.5 3.4 5.5 3.2 0.8 1.2 3.3 0.5 0.1 2.7 9.5 16.0 3.0 1.0 0.1 0.4 6.2 0.7 0.5 2.4 0.0 8.6 3.3 15.6 0.5 11.3 0.2 10.0 10.2 0.1 1.6 0.2 1.5 0.0 4.2 3.2 5.6 1.8 3.3 3.6 1.5 4.1 3.5 5.8 0.1 3.0 8.4 2.1 3.8 2.3 1.2 1.2 5.7 3.9 1.3 0.3 2.9 0.4 2.9 0.5 1.3 4.2 15.3 28.9 21.4 13.7 28.4 10.1 7.8 9.9 16.5 24.5 1.5 3.9 135.4 90.1 16.5 46.0 10.4 0.3 29.7 0.8 23.5 53.3 117.3 2.1 25.0 22.0 0.0 2.5 150.5 67.1 0.3 36.2 7.1 9.1 10.1 4.7 9.3 14.5 3.6 8.4 128.2 27.2 6.1 32.7 6.1 135.5 6.8 24.8 3.6 14.0 14.9 1.3 37.0 63.8 82.8 28.0 1.2 10.1 26.3 8.1 1.0 0.7 14.4 6.0 6.6 14.0 18.9 4.2 4.5 61.5 12.6 0.7 35.8 80.1 1.5 3.4 SLC17A9 "C20orf59, FLJ23412, VNUT" ENSG00000101194 "Solute carrier family 17 member 9" Q9BYT1 20 62952707-62969585 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Exocytosis, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 43.0" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Gastric mucus-secreting cells: 29.0;Hepatocytes: 48.8;Hofbauer cells: 18.0;Intestinal goblet cells: 19.7;Plasma cells: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 35.7;CACO-2: 32.9;Hep G2: 69.5;NB-4: 39.0;RPMI-8226: 36.1;U-937: 43.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047470 Approved Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA047470: AB_2680060" "unprognostic (2.65e-3)" "unprognostic (2.13e-1)" "unprognostic (7.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.33e-3)" "unprognostic (5.33e-2)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (1.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (2.78e-15)" "unprognostic (6.06e-3)" "unprognostic (5.51e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 1.3 1.0 0.3 5.8 0.5 11.4 1.3 0.7 0.7 1.9 0.7 3.7 5.5 1.5 0.2 0.8 1.9 1.3 1.3 0.6 0.8 0.9 43.0 3.5 5.2 1.2 0.9 1.7 1.4 0.0 2.2 1.7 1.3 1.3 3.1 0.0 4.0 0.6 1.0 0.7 4.2 1.4 0.9 11.1 9.5 0.4 1.2 0.7 1.2 0.1 4.2 2.7 1.7 2.0 0.0 0.0 0.0 0.2 0.3 3.1 0.1 35.7 10.0 11.4 18.0 32.9 0.0 25.9 0.0 28.3 0.0 0.0 5.0 0.0 2.8 0.0 0.0 11.5 0.9 69.5 7.7 20.9 0.0 2.5 0.0 13.6 0.0 0.0 7.6 0.1 0.1 14.6 0.0 0.0 0.9 39.0 0.0 12.9 0.2 26.9 0.0 36.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 19.4 2.6 0.0 0.0 1.2 0.0 5.0 0.3 14.2 0.0 43.8 0.0 0.0 0.9 0.0 0.7 1.7 0.5 2.2 0.0 0.4 2.6 1.7 0.0 0.3 0.0 4.9 0.3 0.0 0.1 0.7 0.3 0.5 0.7 0.7 0.6 0.8 1.2 0.9 1.3 0.9 1.2 2.0 1.1 0.0 1.1 0.0 18.2 0.9 0.2 0.3 0.0 0.4 1.0 1.0 1.3 12.8 1.0 0.0 0.0 0.3 5.5 6.4 0.0 0.3 0.7 2.6 7.3 1.4 3.0 1.7 0.7 0.4 0.9 4.0 29.0 2.5 5.1 2.4 1.4 48.8 18.0 0.0 0.4 19.7 0.0 5.1 12.4 0.6 1.2 7.2 5.4 2.8 1.3 0.1 4.1 1.0 0.1 1.7 3.1 0.7 38.6 0.6 0.2 0.4 0.8 0.1 0.0 1.6 4.2 0.4 1.0 0.0 1.1 0.8 3.6 3.8 9.3 0.6 SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.7;breast: 28.4;placenta: 24.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 65.4;Syncytiotrophoblasts: 160.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.9;BEWO: 6.2;CACO-2: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" 46.7 0.6 5.0 1.9 3.3 1.2 28.4 4.7 4.3 0.5 1.0 2.6 9.1 0.5 0.1 0.7 0.5 5.7 0.7 3.4 4.4 2.2 13.8 4.1 0.8 5.2 4.2 0.9 1.7 0.1 0.1 24.1 5.4 0.3 1.8 2.2 1.1 0.1 0.9 1.6 5.6 0.4 4.4 0.5 0.5 0.5 5.7 0.2 0.4 0.8 0.4 1.0 0.4 4.0 0.3 0.9 0.2 0.8 13.9 0.3 6.2 0.1 0.2 0.2 0.6 20.2 0.4 0.2 0.1 0.1 4.6 0.4 0.6 0.5 0.8 0.0 1.0 0.1 1.1 0.8 1.8 0.2 0.1 3.4 0.4 0.1 0.8 0.3 0.0 0.3 0.1 0.6 0.0 1.6 0.1 0.5 3.0 0.7 0.1 0.3 0.1 0.2 0.2 0.2 0.9 0.1 0.3 1.9 0.5 2.6 0.2 0.2 0.6 0.4 0.4 4.1 0.4 0.1 0.1 0.6 1.4 0.2 0.5 6.8 0.8 1.0 0.4 0.6 0.3 0.8 0.4 0.4 0.2 1.3 0.5 0.5 3.3 2.2 0.7 1.0 0.2 0.3 5.0 3.3 4.7 4.3 3.4 4.4 5.2 4.2 5.4 4.4 5.7 4.0 0.2 9.6 5.1 2.3 0.0 0.0 0.5 0.0 0.6 5.3 0.2 0.1 0.4 5.7 0.0 1.8 0.0 65.4 0.1 5.7 1.9 4.4 0.3 0.1 0.0 2.6 1.2 0.0 0.4 0.0 7.4 3.2 0.0 0.1 0.0 0.3 0.0 13.1 5.1 0.0 0.9 1.6 0.0 0.6 0.0 0.7 0.3 0.9 0.0 25.3 0.0 0.8 0.0 4.5 0.3 0.4 1.0 0.0 0.1 0.4 9.3 3.0 0.0 0.2 0.0 1.7 1.6 0.0 0.3 0.0 0.0 160.6 0.2 0.1 6.5 0.4 SLC1A2 "EAAT2, GLT-1" ENSG00000110436 "Solute carrier family 1 member 2" P43004 11 35251205-35420063 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 782.3;choroid plexus: 202.7" "Cell type enriched" "Detected in many" 7 "Astrocytes: 4607.2" "Cancer enriched" "Detected in some" 5 "glioma: 28.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.1;BJ hTERT+: 2.4;fHDF/TERT166: 1.7;Hep G2: 2.9;NTERA-2: 3.1;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002574, HPA009172, HPA067499" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB002574: AB_564087, HPA009172: AB_1849764, HPA067499: " "unprognostic (8.00e-2)" "unprognostic (5.71e-3)" "unprognostic (1.39e-1)" "unprognostic (2.77e-2)" "unprognostic (1.33e-1)" "unprognostic (5.65e-3)" "unprognostic (1.39e-2)" "unprognostic (9.27e-3)" "unprognostic (1.55e-1)" "unprognostic (1.65e-2)" "unprognostic (1.79e-3)" "unprognostic (2.35e-1)" "unprognostic (8.33e-4)" "unprognostic (6.34e-2)" "unprognostic (8.06e-2)" "unprognostic (5.24e-2)" "unprognostic (3.49e-2)" 0.6 4.6 546.9 0.6 731.2 0.4 3.8 388.1 782.3 1.2 202.7 0.2 0.5 1.0 0.3 0.2 0.3 0.2 0.9 631.1 432.5 0.2 34.9 0.6 1.9 450.6 533.6 0.1 9.5 0.1 2.6 1.1 384.2 0.3 0.1 60.1 4.6 0.1 0.3 1.3 0.2 0.3 409.7 0.5 2.1 1.7 498.7 0.2 0.3 0.5 1.6 0.3 0.6 453.4 0.0 0.1 0.5 0.0 0.2 2.1 0.0 0.5 2.4 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.3 2.9 0.1 0.3 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.2 0.0 1.1 0.0 0.1 0.5 0.0 0.3 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.5 0.0 0.1 1.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.5 0.2 0.1 0.1 0.1 0.1 546.9 731.2 388.1 782.3 631.1 432.5 450.6 533.6 384.2 409.7 498.7 453.4 0.4 3.2 4.8 4607.2 0.4 2.9 0.0 0.0 0.0 109.9 8.1 2.4 3.1 0.0 0.0 0.0 148.0 25.6 0.3 0.1 0.0 0.1 96.6 1.8 11.7 1.6 0.0 0.0 83.7 3.4 1.0 3.1 1.1 1.5 0.0 0.7 0.0 6.7 3.3 6.7 81.5 0.0 0.0 0.0 3.0 97.9 0.0 0.6 1.8 194.9 31.6 10.1 0.0 634.9 12.3 0.4 0.0 0.0 0.1 0.3 0.0 0.1 0.8 161.2 0.0 0.3 1.8 0.5 1.3 0.0 1.1 269.4 0.2 0.0 0.0 0.1 SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1735.2;Microglial cells: 332.6;Muller glia cells: 472.6;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 249.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 50.0;CACO-2: 112.6;HaCaT: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" 30.7 16.4 500.4 7.4 544.2 3.3 17.7 549.4 776.8 8.7 400.6 3.0 0.5 1.6 1.1 10.5 6.0 8.0 45.4 514.6 502.5 2.2 3.8 10.2 17.4 477.6 510.1 12.6 5.0 2.2 18.1 20.3 502.4 3.2 1.1 221.1 4.7 4.7 14.1 6.0 3.2 4.1 495.4 9.3 2.2 1.2 532.8 3.6 3.4 9.2 5.4 7.0 5.3 494.9 1.3 0.2 50.0 5.3 5.9 14.3 37.7 0.3 0.0 2.4 4.9 112.6 5.6 0.0 27.8 2.3 1.0 71.4 16.9 9.1 2.2 1.8 33.0 0.0 0.5 0.0 2.5 1.3 0.6 26.9 34.5 14.4 5.3 1.8 0.0 1.1 0.0 0.2 8.7 0.2 0.1 0.1 6.0 0.1 5.9 0.0 0.5 0.0 0.1 3.1 4.7 0.0 5.1 14.6 2.1 24.4 0.2 3.1 0.0 6.2 10.3 0.1 20.7 0.0 0.0 0.3 21.7 37.7 12.6 0.0 1.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 500.4 544.2 549.4 776.8 514.6 502.5 477.6 510.1 502.4 495.4 532.8 494.9 1.1 3.2 0.5 1735.2 0.7 10.7 14.3 19.0 83.1 7.1 3.7 3.4 36.0 0.0 3.1 0.0 2.1 32.9 0.1 0.0 0.0 0.8 0.7 16.3 1.2 8.9 0.0 0.8 2.6 0.0 15.9 7.8 2.0 11.7 0.0 0.2 1.1 0.5 41.2 3.3 4.7 0.0 0.0 77.6 5.9 4.1 4.4 59.6 7.2 332.6 3.3 472.6 0.0 237.7 249.0 0.3 0.0 0.0 0.7 5.2 0.0 0.0 5.3 19.1 6.6 2.6 3.1 0.3 0.3 32.7 7.1 9.2 1.0 20.7 0.0 3.6 SLC1A4 "ASCT1, SATT" ENSG00000115902 "Solute carrier family 1 member 4" P43007 2 64988477-65023865 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.9" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Granulosa cells: 49.2;Melanocytes: 85.4;Plasma cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 294.5;U-266/70: 132.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034963, HPA034964" Approved Enhanced Centrosome NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Centrosome "HPA034963: AB_2797223, HPA034964: AB_2674386" "unprognostic (7.61e-2)" "prognostic favorable (3.59e-4)" "unprognostic (2.49e-1)" "unprognostic (3.19e-3)" "unprognostic (1.26e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.23e-5)" "unprognostic (1.26e-2)" "unprognostic (2.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.28e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.37e-3)" "unprognostic (4.14e-2)" "unprognostic (3.53e-2)" "unprognostic (1.98e-2)" 4.3 26.4 49.1 9.1 46.8 13.4 13.6 32.1 48.6 14.0 18.0 9.4 6.1 12.8 8.2 7.5 4.8 3.9 6.2 43.4 56.6 1.9 9.0 4.9 10.7 37.2 43.1 13.2 29.6 5.5 13.7 6.6 52.1 9.6 8.4 19.3 7.5 7.1 40.1 18.6 5.6 12.3 29.5 7.5 8.1 11.7 59.9 20.5 5.7 17.0 19.0 4.8 6.2 30.3 15.3 11.6 6.6 34.9 14.7 9.5 9.4 28.5 14.0 11.7 19.8 3.2 2.2 49.7 6.5 44.8 14.7 43.2 13.7 3.6 12.0 20.1 5.4 26.0 13.1 30.9 31.0 43.8 23.1 4.4 73.8 15.8 24.2 3.9 7.3 49.1 20.7 122.0 8.4 13.5 37.7 29.1 4.7 20.1 13.9 13.5 1.9 125.5 4.9 7.7 29.3 14.1 17.9 16.1 294.5 3.0 19.3 47.8 1.6 16.0 19.0 31.2 17.5 132.8 71.2 118.8 23.6 86.5 86.2 0.0 2.1 1.8 0.9 4.8 1.2 0.9 0.9 1.5 3.9 0.3 0.0 0.8 0.0 5.1 9.4 7.2 3.5 1.4 49.1 46.8 32.1 48.6 43.4 56.6 37.2 43.1 52.1 29.5 59.9 30.3 3.6 0.0 2.7 69.9 13.6 20.0 2.1 6.7 46.1 6.3 21.0 7.1 5.5 1.5 1.7 1.8 33.3 2.4 20.2 2.9 0.0 2.0 32.4 5.4 8.2 5.3 8.4 6.1 20.6 9.3 1.3 4.0 5.1 5.6 7.0 49.2 7.5 13.1 17.7 6.7 25.5 9.0 6.1 6.8 11.8 47.5 11.1 11.1 85.4 8.4 5.1 14.6 2.1 5.0 3.9 7.1 0.8 29.7 65.7 2.6 0.4 1.5 5.4 17.7 0.0 5.1 7.3 2.0 0.9 5.9 6.1 2.5 10.9 0.4 5.8 1.0 SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 207.7;Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 72.3" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cell line enriched" "Detected in some" 8 "HHSteC: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" 1.6 0.2 1.5 0.2 1.0 0.0 1.1 1.0 1.5 1.4 0.8 1.0 2.3 1.3 0.0 1.2 1.8 5.2 1.6 1.2 1.1 0.4 1.0 0.6 0.1 1.6 1.9 2.4 0.2 0.4 0.1 0.2 1.8 0.8 0.0 40.2 0.5 0.0 1.3 0.8 3.1 0.0 1.5 0.0 0.8 0.5 2.3 0.0 0.6 3.0 0.0 1.0 1.1 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.0 1.0 1.5 1.2 1.1 1.6 1.9 1.8 1.5 2.3 1.2 1.9 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.6 0.0 0.0 0.0 70.9 0.1 3.0 2.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.2 5.9 4.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 1.0 0.0 0.3 0.0 0.0 1.2 0.5 0.0 7.5 0.0 8.5 16.5 0.0 0.1 0.0 4.0 1.2 0.7 0.0 17.7 0.7 0.0 72.3 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.3 0.0 SLC22A12 "OAT4L, RST, URAT1" ENSG00000197891 "Solute carrier family 22 member 12" Q96S37 11 64590641-64602353 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 204 "kidney: 109.4" "Cell type enriched" "Detected in some" 17 "Proximal tubular cells: 173.1" "Cancer enriched" "Detected in some" 4 "renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024575 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA024575: AB_1858650" "unprognostic (5.88e-2)" "unprognostic (2.33e-1)" "prognostic favorable (2.63e-4)" "unprognostic (6.19e-2)" "unprognostic (3.91e-2)" 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 109.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 173.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 SLC22A18AS "BWR1B, BWSCR1B, ORCTL2S, p27-BWR1B, SLC22A1LS" ENSG00000254827 "Solute carrier family 22 member 18 antisense" Q8N1D0 11 2887344-2903575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 17.7;kidney: 11.1;liver: 14.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 163.3;Paneth cells: 124.4;Proximal enterocytes: 75.7;Proximal tubular cells: 104.0;Syncytiotrophoblasts: 80.7;Undifferentiated cells: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 7.0" "Group enriched" "Detected in many" 8 "dendritic cells: 3.9;granulocytes: 4.0;monocytes: 7.0" "Cell line enhanced" "Detected in some" "A549: 9.4;CAPAN-2: 9.4;MCF7: 18.8;OE19: 8.4;SK-MEL-30: 35.8;WM-115: 14.8" HPA068288 Enhanced Approved Nucleoplasm No NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA068288: AB_2685969" "unprognostic (1.43e-1)" "unprognostic (9.21e-2)" "unprognostic (3.36e-1)" "unprognostic (8.05e-2)" "unprognostic (1.33e-3)" "unprognostic (3.16e-2)" "unprognostic (5.14e-3)" "unprognostic (9.76e-2)" "unprognostic (1.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.10e-2)" "unprognostic (1.48e-2)" "unprognostic (9.52e-2)" "unprognostic (1.77e-1)" "unprognostic (2.39e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" 3.2 0.6 0.5 2.2 0.6 0.2 0.7 0.5 1.7 0.7 0.5 17.7 13.4 0.8 0.4 1.2 0.4 1.7 0.3 0.6 1.0 11.1 14.9 0.6 0.4 0.9 0.9 0.4 0.3 0.0 0.3 2.3 1.1 0.8 10.2 0.3 1.8 0.1 0.1 1.1 9.7 0.7 0.8 0.7 1.6 0.5 0.8 0.1 0.3 0.0 0.1 0.7 0.9 1.1 1.2 9.4 0.3 0.5 0.0 0.0 0.9 0.5 0.4 0.0 0.2 2.2 9.4 0.0 0.8 0.0 0.6 0.5 0.0 0.3 0.0 0.4 0.1 0.0 0.8 5.8 0.7 0.0 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.5 0.0 0.9 0.0 18.8 0.0 0.4 0.2 8.4 0.3 0.3 0.0 1.0 0.8 0.0 0.1 0.3 0.9 0.4 35.8 0.2 0.0 0.9 1.9 0.0 0.7 0.3 0.2 0.0 0.0 0.2 0.2 2.6 14.8 4.0 7.0 1.2 0.2 3.9 0.1 0.0 0.1 0.2 3.9 0.0 0.0 0.1 1.6 0.4 2.9 0.0 0.6 2.4 0.5 0.6 0.5 1.7 0.6 1.0 0.9 0.9 1.1 0.8 0.8 1.1 0.6 0.0 0.5 0.0 1.3 0.5 1.1 6.3 1.2 0.0 1.2 0.9 0.4 1.5 2.7 7.3 0.0 19.5 0.4 163.3 9.8 1.7 0.1 0.1 0.3 0.7 9.1 3.2 0.4 0.8 9.8 1.4 2.6 0.5 1.3 0.0 2.9 22.7 17.7 0.0 0.1 26.2 6.1 6.3 5.5 0.2 0.3 6.4 3.6 0.0 4.6 0.0 0.0 0.0 0.1 2.4 124.4 0.0 0.0 1.0 75.7 104.0 1.0 0.0 0.0 0.0 0.6 0.1 0.4 2.1 1.1 80.7 0.9 0.8 48.5 2.5 SLC22A3 "EMT, OCT3" ENSG00000146477 "Solute carrier family 22 member 3" O75751 6 160348378-160452577 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 67.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 78.9;Hepatocytes: 68.8;Leydig cells: 33.8;Pancreatic endocrine cells: 57.3;Skeletal myocytes: 29.8" "Cancer enhanced" "Detected in many" "prostate cancer: 19.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 27.6;HeLa: 38.1;Hep G2: 23.7;OE19: 12.0;RPTEC TERT1: 13.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029750 Approved Approved Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Vesicles Cytosol "HPA029750: AB_10603888" "unprognostic (8.61e-2)" "prognostic unfavorable (7.19e-5)" "unprognostic (4.14e-1)" "unprognostic (1.49e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (3.36e-2)" "unprognostic (9.74e-2)" "unprognostic (9.36e-4)" "unprognostic (1.33e-2)" "unprognostic (2.58e-2)" "unprognostic (7.28e-2)" "unprognostic (7.96e-2)" "unprognostic (5.21e-2)" "unprognostic (8.13e-4)" "prognostic unfavorable (7.26e-4)" 11.7 15.2 2.1 3.8 2.7 0.0 6.6 3.3 2.1 15.9 1.8 8.8 1.7 18.4 27.6 7.7 18.7 11.0 1.5 2.0 3.5 6.3 34.9 16.4 16.2 6.2 3.8 21.1 0.7 0.2 1.3 44.3 4.5 43.4 2.4 0.2 51.8 52.6 67.4 10.7 5.7 26.3 3.3 0.6 6.0 2.6 4.2 0.5 2.0 8.5 4.9 6.2 15.7 3.2 0.0 27.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.5 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.4 0.0 0.0 0.0 38.1 23.7 1.2 0.0 0.0 0.8 6.9 3.4 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.0 12.0 7.7 0.0 0.0 0.0 13.8 0.0 0.0 0.0 3.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.3 2.1 2.0 3.5 6.2 3.8 4.5 3.3 4.2 3.2 0.6 16.0 78.9 6.2 0.1 4.7 0.3 2.1 2.8 0.2 0.2 0.3 2.9 5.7 6.4 0.0 0.0 0.3 0.1 0.2 5.9 8.2 0.6 0.2 10.2 1.0 0.0 0.0 0.5 3.0 0.3 10.0 12.8 0.3 2.5 0.8 0.0 68.8 0.7 0.0 25.1 1.6 2.0 1.0 2.4 1.6 33.8 0.3 3.6 7.5 0.0 0.0 0.0 19.6 0.2 57.3 0.1 24.5 0.1 6.1 2.1 2.9 0.8 0.1 0.0 29.8 12.3 0.3 0.2 3.7 6.7 0.4 1.2 0.0 2.8 0.8 SLC25A1 "CTP, SLC20A3" ENSG00000100075 "Solute carrier family 25 member 1" P53007 22 19175581-19178739 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 197.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 221.1;Proximal enterocytes: 304.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 101.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.12e-1)" "unprognostic (3.98e-1)" "unprognostic (8.17e-2)" "unprognostic (1.13e-1)" "unprognostic (9.39e-2)" "unprognostic (2.61e-2)" "unprognostic (3.11e-2)" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (5.74e-2)" "unprognostic (3.90e-2)" "unprognostic (5.72e-2)" "unprognostic (4.52e-2)" "unprognostic (1.84e-1)" "unprognostic (3.46e-2)" "unprognostic (6.14e-2)" "unprognostic (9.03e-2)" 113.3 76.3 45.8 22.3 46.9 14.2 90.3 49.5 58.6 43.5 47.6 63.9 114.1 40.0 16.2 59.2 34.7 21.5 27.3 41.5 65.8 86.8 197.7 33.6 21.4 61.0 58.3 43.6 54.8 33.1 39.3 27.4 73.0 53.9 33.9 5.6 39.5 30.0 17.3 49.1 92.4 21.0 49.4 31.4 52.9 36.3 51.8 16.3 46.1 7.7 25.5 43.9 40.8 55.2 111.9 114.3 85.9 73.6 209.1 102.5 91.2 77.5 96.9 65.7 90.4 136.4 77.2 66.9 38.8 110.5 70.5 95.4 82.9 138.1 37.2 59.6 164.1 35.5 97.7 278.4 148.2 67.3 107.5 145.1 81.7 75.7 58.4 73.3 62.8 53.4 184.6 61.9 74.7 288.1 37.0 80.8 57.5 173.5 70.0 70.4 44.6 29.9 196.2 135.8 55.5 71.2 83.1 163.0 48.6 52.6 122.6 171.7 63.6 80.3 69.3 62.0 53.2 78.2 39.9 35.4 82.5 31.5 41.4 11.6 15.7 101.9 16.6 17.9 10.6 33.3 18.7 18.2 13.7 43.5 16.7 14.3 8.1 13.7 23.8 10.5 19.6 10.6 45.8 46.9 49.5 58.6 41.5 65.8 61.0 58.3 73.0 49.4 51.8 55.2 18.5 9.6 18.9 10.7 35.0 22.0 27.2 21.6 31.9 7.8 44.2 41.9 7.2 38.6 17.0 33.1 2.1 135.6 18.4 178.6 50.9 33.5 30.5 41.4 37.0 16.8 41.0 21.7 5.2 45.6 139.5 27.1 50.4 83.7 2.5 67.5 21.4 221.1 47.5 13.5 6.1 107.3 28.5 30.5 18.2 98.8 28.9 32.6 28.4 2.8 29.6 27.7 16.5 3.0 10.1 39.7 128.1 29.3 38.7 28.7 304.3 127.3 11.1 4.2 13.1 14.5 37.8 15.3 29.5 60.5 30.4 127.7 24.6 55.7 108.3 30.4 SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA036243: AB_2675019, HPA044580: AB_10962723" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.23e-2)" "unprognostic (9.13e-3)" "unprognostic (1.92e-1)" "unprognostic (4.13e-2)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (8.37e-3)" "unprognostic (2.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.06e-2)" "unprognostic (1.44e-3)" 10.3 3.6 5.1 2.1 5.3 3.7 4.1 7.1 7.9 2.1 0.0 3.2 3.8 3.5 3.2 2.6 2.1 2.3 2.8 5.0 5.6 5.8 11.4 3.1 2.7 2.7 3.5 2.3 5.1 3.5 2.6 2.8 3.4 8.2 2.8 4.7 4.5 2.8 4.9 3.0 3.8 2.6 2.2 2.4 4.5 1.5 7.0 2.0 3.5 2.3 2.0 2.7 2.1 6.1 2.8 1.1 3.2 4.4 4.2 5.0 3.4 3.8 4.2 2.4 2.6 6.6 1.9 3.0 2.7 7.6 1.3 1.6 10.2 1.9 6.1 2.2 6.3 1.6 3.5 2.9 5.1 5.2 3.4 4.3 4.9 4.6 6.4 3.6 2.0 2.6 1.8 4.8 5.2 2.6 2.9 3.7 0.7 0.8 14.8 1.6 2.3 1.0 6.8 9.2 2.2 1.8 5.4 5.2 4.4 2.2 2.9 2.1 8.9 3.6 4.8 6.1 4.5 4.9 2.8 4.9 3.5 4.2 1.6 1.4 0.7 0.7 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.8 0.4 0.6 1.3 0.6 0.4 0.8 0.4 0.3 5.1 5.3 7.1 7.9 5.0 5.6 2.7 3.5 3.4 2.2 7.0 6.1 9.6 44.8 20.7 23.5 9.9 6.4 6.3 4.9 4.6 19.2 11.0 6.7 10.4 12.8 7.4 12.9 39.6 19.0 12.4 12.9 11.7 8.1 9.9 9.6 9.3 7.8 15.0 9.9 44.0 19.2 32.3 8.8 20.9 14.1 8.2 6.1 13.9 37.7 10.6 20.2 53.7 9.4 8.2 10.3 6.5 13.0 3.1 7.9 1.8 13.1 8.2 9.5 15.5 29.7 48.0 14.4 7.8 7.9 16.4 13.5 17.7 21.4 9.9 31.2 0.0 13.4 11.3 4.5 2.5 10.5 6.8 59.8 9.4 9.4 9.0 10.6 SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 143.8;choroid plexus: 90.7;liver: 111.5" "Group enriched" "Detected in many" 4 "Astrocytes: 195.2;Hepatocytes: 72.8" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;BEWO: 8.5" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" 14.4 1.0 130.1 0.3 132.1 0.1 7.2 116.5 141.1 2.5 90.7 2.9 0.3 2.9 0.2 0.3 3.8 0.9 2.8 119.4 123.3 1.9 111.5 1.2 0.3 121.7 129.2 1.2 1.1 0.2 1.5 0.1 112.5 7.8 0.1 1.9 0.5 0.4 6.2 1.2 1.9 0.5 106.5 4.8 1.5 4.2 143.8 0.3 0.6 4.0 0.1 0.8 1.4 110.7 0.3 0.6 2.2 0.4 3.8 0.0 8.5 0.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.5 0.7 0.0 0.0 0.0 0.3 1.0 0.3 0.3 0.5 1.5 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.3 0.0 0.4 0.1 0.5 2.0 0.9 1.4 2.9 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.4 0.7 1.6 2.5 1.0 0.1 0.1 0.3 0.2 0.3 0.9 1.2 0.0 1.8 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.1 132.1 116.5 141.1 119.4 123.3 121.7 129.2 112.5 106.5 143.8 110.7 1.0 28.9 10.3 195.2 0.3 0.0 0.3 0.1 0.6 0.6 0.3 0.0 1.5 5.7 7.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.6 0.4 0.9 1.7 0.0 10.7 2.0 0.0 0.3 4.7 0.0 0.7 6.3 8.5 3.6 72.8 0.3 0.0 3.0 0.3 0.0 4.1 0.3 0.6 0.9 3.9 0.0 10.3 0.1 2.2 1.0 13.0 11.5 0.0 0.0 2.6 0.1 4.3 0.1 0.8 15.8 3.4 0.0 2.7 2.5 4.8 5.9 0.0 0.1 1.8 2.6 2.6 0.0 0.2 SLC25A20 "CAC, CACT" ENSG00000178537 "Solute carrier family 25 member 20" O43772 3 48856926-48898904 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.2;Hepatocytes: 64.2;Proximal enterocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 96.1;RPMI-8226: 138.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016862, HPA029863" Approved Approved Mitochondria,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Mitochondria, Cytosol" "HPA016862: AB_1857028, HPA029863: AB_10602893" "unprognostic (1.02e-1)" "unprognostic (1.84e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-2)" "unprognostic (5.18e-2)" "unprognostic (3.97e-2)" "unprognostic (1.03e-1)" "unprognostic (5.96e-3)" "unprognostic (4.06e-1)" "unprognostic (1.73e-1)" "unprognostic (1.36e-2)" "unprognostic (2.51e-1)" "unprognostic (3.71e-3)" "unprognostic (3.34e-1)" "unprognostic (5.12e-1)" "unprognostic (4.22e-2)" "unprognostic (3.49e-2)" 20.7 29.9 16.3 11.9 18.2 10.7 17.9 18.6 16.4 8.3 15.3 26.5 65.6 10.4 4.6 9.1 12.8 15.7 62.8 15.5 17.9 25.6 148.3 15.6 14.6 17.7 17.4 5.9 30.4 17.3 11.6 7.3 17.8 11.7 23.5 4.5 19.9 9.0 66.5 10.4 52.7 15.1 17.4 20.6 21.0 9.1 17.5 17.3 11.4 61.1 16.1 11.3 8.4 18.4 4.1 12.8 9.7 13.8 30.1 11.8 1.9 22.3 11.8 15.2 15.8 16.3 19.1 19.0 15.6 35.1 18.7 4.1 24.5 9.8 11.6 47.9 11.8 26.4 19.2 20.4 14.0 27.8 48.1 14.9 11.2 20.6 3.8 6.1 20.2 28.1 24.1 96.1 20.2 10.9 30.4 13.7 5.1 22.9 27.6 10.6 5.9 138.4 16.4 10.1 3.9 13.6 20.7 0.2 11.4 13.6 30.5 12.9 16.6 17.2 3.2 25.5 16.4 35.6 27.0 21.8 24.5 19.5 23.3 60.8 101.1 215.2 97.4 79.7 62.2 36.8 53.1 71.2 97.5 33.0 41.2 69.1 48.6 64.6 83.7 120.5 60.7 112.3 16.3 18.2 18.6 16.4 15.5 17.9 17.7 17.4 17.8 17.4 17.5 18.4 7.5 6.4 2.7 13.1 7.0 1.8 2.5 4.6 3.4 1.1 4.0 3.6 42.2 4.3 4.4 0.0 6.2 2.3 13.6 28.4 3.9 3.5 1.3 2.3 4.6 5.5 7.3 16.4 2.2 4.3 2.3 6.1 9.2 2.1 1.3 3.8 7.5 64.2 16.9 0.0 3.8 12.7 2.0 13.4 4.5 1.8 10.5 10.0 1.8 1.0 31.3 2.9 32.0 1.0 6.0 3.7 16.4 12.4 12.6 3.9 51.8 16.7 5.9 1.3 0.0 5.4 5.3 8.3 7.1 4.1 1.3 1.2 14.4 27.7 16.6 2.9 SLC25A38 FLJ20551 ENSG00000144659 "Solute carrier family 25 member 38" Q96DW6 3 39383370-39397351 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041027 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA041027: AB_10794403" "unprognostic (3.82e-2)" "unprognostic (3.27e-2)" "unprognostic (1.96e-1)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-2)" "unprognostic (3.94e-2)" "unprognostic (1.94e-1)" "unprognostic (1.26e-2)" "unprognostic (5.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-1)" "prognostic favorable (7.29e-4)" 19.1 35.4 22.2 18.8 23.3 70.0 21.0 25.9 26.8 23.8 33.6 28.1 25.3 27.3 27.6 14.5 27.3 19.4 20.7 22.9 26.3 28.7 58.0 21.0 36.2 24.2 24.1 44.1 45.6 38.7 30.7 15.4 25.3 29.2 36.9 23.0 22.5 23.9 48.2 16.7 25.2 20.3 22.6 27.2 33.8 18.7 26.0 33.6 52.0 35.7 35.4 27.8 19.1 23.3 24.3 38.3 24.3 41.2 56.4 46.4 30.8 33.6 46.1 48.3 43.7 26.3 5.6 67.8 19.6 31.6 40.7 18.4 55.2 40.1 36.0 43.6 45.0 52.0 33.5 40.2 75.6 37.7 33.9 58.8 46.1 46.2 93.2 44.6 31.5 52.8 47.7 40.6 36.4 35.2 44.7 67.0 66.2 35.9 44.3 16.2 26.4 47.7 37.5 45.4 24.3 31.1 11.9 65.9 34.0 44.5 33.5 35.0 26.9 38.3 26.4 56.2 48.9 54.7 93.1 41.9 29.3 48.3 24.7 30.7 9.6 18.1 38.8 5.7 44.7 50.8 39.1 43.3 14.9 37.8 41.7 40.5 1.0 57.0 8.4 18.5 55.3 29.2 22.2 23.3 25.9 26.8 22.9 26.3 24.2 24.1 25.3 22.6 26.0 23.3 10.4 22.4 27.4 8.5 35.6 11.5 13.0 12.5 28.5 13.2 26.1 22.6 16.8 22.8 9.6 27.6 6.2 35.2 33.1 21.9 21.5 15.7 6.5 26.6 16.3 11.1 12.6 73.7 8.9 16.9 32.6 13.7 16.8 38.5 22.2 24.0 9.7 27.0 15.2 5.0 10.1 25.6 12.2 7.0 13.7 12.9 15.5 9.8 12.4 1.9 11.2 18.9 29.9 7.1 6.2 13.4 22.2 13.5 23.3 17.7 23.1 31.3 12.3 12.6 6.6 15.2 14.9 11.0 7.8 19.4 10.2 19.4 36.6 32.8 26.7 8.4 SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 93.6;Late spermatids: 169.6;Spermatocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (5.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (6.87e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-3)" "unprognostic (1.26e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.52e-4)" "unprognostic (8.27e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (2.08e-2)" 9.0 3.1 3.1 5.0 3.5 12.0 4.1 3.4 4.4 5.4 2.3 4.5 7.5 4.1 4.7 5.6 3.4 5.0 4.5 3.7 4.1 6.3 3.1 5.2 5.7 3.4 3.3 3.8 5.9 8.3 4.1 4.7 4.0 3.5 4.1 4.8 4.7 3.7 6.1 5.7 6.0 5.8 2.6 5.7 4.3 8.0 3.1 5.6 4.6 7.4 6.5 4.3 3.5 4.4 12.4 10.1 7.3 11.6 34.4 15.2 7.4 10.6 10.7 8.8 12.6 13.0 5.2 26.2 5.9 24.2 12.5 6.1 19.6 14.5 16.5 18.0 6.1 8.0 27.5 18.0 19.1 12.5 11.1 15.3 16.7 13.4 16.6 13.6 16.1 24.4 17.9 20.2 19.1 7.3 15.2 3.2 9.2 12.7 7.1 10.6 9.9 16.1 8.7 8.9 15.2 10.0 8.3 10.1 6.0 12.2 5.4 13.7 17.3 14.7 17.4 7.2 12.8 7.7 17.5 17.5 19.4 9.3 12.3 16.7 1.5 2.8 1.6 3.1 2.7 2.6 1.7 2.3 1.1 1.5 1.6 1.8 1.3 1.9 1.3 0.5 2.7 0.9 3.1 3.5 3.4 4.4 3.7 4.1 3.4 3.3 4.0 2.6 3.1 4.4 4.3 9.6 1.1 13.4 9.3 4.7 5.8 7.6 8.6 4.0 5.1 3.8 6.3 5.7 4.6 1.8 4.2 3.7 7.6 3.8 17.6 9.5 93.6 2.5 5.3 4.3 3.6 6.9 22.0 7.2 14.1 5.2 8.2 5.1 3.8 3.4 3.9 3.6 11.7 1.7 21.3 5.8 0.0 5.7 4.7 169.6 3.7 8.8 1.8 19.7 8.4 5.3 3.1 16.1 22.1 7.3 7.2 4.1 14.3 3.8 17.4 16.8 2.2 3.7 0.0 4.3 4.5 44.0 10.2 11.7 5.8 4.0 6.5 4.8 3.6 3.8 SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1120.4" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 2328.4" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036055 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" 1.1 0.0 0.0 19.7 0.0 0.0 59.5 0.2 0.1 0.3 0.0 1120.4 576.9 0.9 15.3 0.5 0.8 17.8 0.0 0.0 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.1 878.8 0.1 0.0 129.9 0.0 0.1 118.5 15.0 0.0 0.0 1.3 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 165.9 4.2 0.0 0.3 0.0 0.0 0.0 51.4 41.7 0.3 34.3 0.0 0.0 0.0 0.0 0.0 2328.4 0.0 0.0 6.4 1.8 0.1 0.3 14.3 0.0 110.2 0.0 0.0 0.1 0.0 0.2 26.7 0.2 0.0 0.1 0.0 0.0 114.3 32.5 0.0 0.0 0.0 0.6 0.3 0.1 0.0 89.9 0.0 0.0 0.0 101.6 182.1 0.0 503.4 0.0 0.0 0.3 388.9 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 0.0 86.0 0.1 SLC29A4 "ENT4, FLJ34923" ENSG00000164638 "Solute carrier family 29 member 4" Q7RTT9 7 5274369-5306912 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 43.3;choroid plexus: 55.5" "Group enriched" "Detected in many" 5 "Enteroendocrine cells: 103.2;Horizontal cells: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 49.2;SH-SY5Y: 70.7;U-2 OS: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052829 Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Microtubules, Cytokinetic bridge" "HPA052829: AB_2681967" "unprognostic (6.04e-2)" "unprognostic (1.22e-2)" "unprognostic (8.49e-5)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" "unprognostic (4.24e-2)" "unprognostic (9.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.55e-2)" "unprognostic (5.73e-2)" "prognostic favorable (4.52e-4)" "unprognostic (2.06e-1)" "unprognostic (3.02e-2)" "unprognostic (3.24e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-3)" "unprognostic (6.60e-2)" 43.3 8.2 13.2 0.7 16.2 0.6 13.3 16.0 20.0 4.9 55.5 3.1 4.6 5.4 5.0 1.1 4.0 1.6 3.7 26.3 28.5 7.9 9.2 0.9 0.2 23.2 26.1 2.2 15.4 1.7 3.6 0.6 23.6 5.8 1.8 4.1 1.3 0.7 2.6 3.0 5.5 1.8 17.2 1.6 6.5 2.6 30.0 0.3 9.7 0.4 0.1 2.4 2.0 7.4 0.0 21.7 12.6 49.2 0.6 0.2 2.4 1.8 0.1 1.6 0.9 12.3 0.4 0.0 2.4 1.9 8.1 0.3 4.8 0.4 0.5 0.1 2.8 0.2 0.7 18.3 3.8 0.2 3.0 1.5 16.2 0.3 0.9 2.9 1.5 4.5 3.6 0.1 1.2 10.8 2.0 0.9 16.0 1.5 1.3 8.3 2.1 1.9 3.2 0.5 8.4 70.7 1.3 4.4 0.9 10.7 5.5 5.9 0.7 17.3 23.4 1.6 0.5 1.1 0.0 0.1 2.2 0.7 8.0 0.8 0.3 0.2 0.2 0.1 0.4 0.2 0.1 0.2 0.1 0.4 0.2 0.2 1.3 1.6 0.1 0.3 0.1 0.1 13.2 16.2 16.0 20.0 26.3 28.5 23.2 26.1 23.6 17.2 30.0 7.4 0.5 3.2 0.5 8.8 0.0 0.1 0.2 0.1 0.0 6.9 0.7 0.6 2.5 0.0 0.2 0.0 16.7 0.3 0.2 6.3 0.0 5.3 0.1 3.3 3.0 0.6 103.2 0.0 2.4 0.2 0.4 2.2 2.0 0.7 0.0 25.7 0.0 1.0 0.4 168.2 14.3 4.4 0.0 0.3 0.7 0.7 0.3 0.3 0.0 0.0 0.1 4.8 0.0 4.0 0.6 1.4 0.5 0.4 0.1 2.3 0.8 0.2 1.4 1.6 0.0 0.5 2.2 0.4 4.2 0.1 0.3 0.3 0.3 1.7 1.0 0.2 SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Oligodendrocytes: 14.5;Syncytiotrophoblasts: 36.7" "Cancer enriched" "Detected in many" 6 "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;hTERT-RPE1: 14.8;SuSa: 21.7;U-2 OS: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Cell Junctions" "HPA031593: AB_10600810, HPA031594: AB_2673948" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-2)" "unprognostic (5.55e-3)" "unprognostic (2.18e-1)" "unprognostic (6.02e-2)" "unprognostic (2.24e-3)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.55e-3)" 0.5 1.0 3.6 0.3 4.8 0.0 1.1 7.8 4.6 3.0 87.3 2.1 7.3 8.2 2.1 6.1 2.8 2.6 10.7 5.7 2.6 5.8 6.8 3.1 0.1 2.3 3.1 1.2 1.1 2.3 1.4 1.6 2.5 22.4 1.0 2.3 5.1 9.3 3.8 2.7 9.8 3.1 1.6 0.1 14.3 0.4 3.4 1.0 0.2 4.1 1.2 3.5 1.2 3.1 2.5 0.9 2.3 0.0 1.4 0.7 0.1 1.5 5.4 0.7 2.9 0.0 7.6 0.3 1.2 0.1 5.7 5.9 0.0 0.5 1.0 0.0 5.3 0.0 0.8 0.1 0.2 0.0 0.0 1.0 0.5 0.6 0.1 14.8 0.4 0.4 0.5 0.8 0.1 0.8 0.1 0.1 2.0 0.0 0.5 0.0 1.0 2.2 1.6 0.8 0.2 0.7 0.1 2.1 0.0 21.7 0.1 0.0 0.1 0.2 7.6 0.2 0.9 3.2 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 4.8 7.8 4.6 5.7 2.6 2.3 3.1 2.5 1.6 3.4 3.1 0.2 0.0 7.7 24.8 0.1 2.0 1.0 3.3 8.6 0.4 0.5 2.2 6.3 0.0 2.2 0.0 0.0 2.0 0.1 1.2 3.9 1.5 0.1 3.4 0.4 2.3 4.2 0.0 8.0 0.2 0.6 2.2 2.6 1.6 0.0 0.4 0.0 1.1 0.3 0.0 3.2 0.2 6.1 0.0 0.3 0.0 0.0 0.1 0.0 4.7 0.1 9.8 0.0 4.5 14.5 1.1 2.4 1.5 1.6 10.5 0.5 0.5 10.4 0.5 0.0 2.1 1.3 0.0 0.0 8.6 1.8 36.7 0.2 3.5 0.4 1.3 SLC2A4 GLUT4 ENSG00000181856 "Solute carrier family 2 member 4" P14672 17 7281718-7288257 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 98.8;skeletal muscle: 223.6" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 135.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "Hep G2: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016544 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016544: AB_629533" "unprognostic (2.53e-1)" "unprognostic (7.40e-3)" "unprognostic (2.27e-1)" "unprognostic (8.12e-4)" "unprognostic (2.40e-1)" "unprognostic (6.28e-2)" "unprognostic (1.70e-2)" "unprognostic (1.66e-2)" "unprognostic (1.35e-1)" "unprognostic (3.83e-2)" "unprognostic (9.66e-2)" "unprognostic (2.24e-2)" "unprognostic (1.34e-3)" "unprognostic (4.23e-2)" "unprognostic (3.10e-1)" "unprognostic (2.30e-2)" "unprognostic (2.07e-2)" 16.9 5.2 1.4 0.2 1.7 1.1 11.2 0.9 1.5 9.2 0.9 53.1 0.8 9.3 1.2 5.9 11.3 0.7 98.8 1.3 1.1 2.6 3.7 2.1 0.2 1.0 1.5 3.2 0.8 3.4 4.4 0.6 1.2 9.9 1.1 0.4 6.3 3.3 223.6 4.1 9.7 4.3 1.0 0.3 11.7 3.3 1.3 0.1 4.5 63.2 0.0 27.0 5.6 1.1 0.0 0.0 0.4 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 1.7 0.9 1.5 1.3 1.1 1.0 1.5 1.2 1.0 1.3 1.1 1.7 0.0 0.0 1.0 0.0 1.8 0.9 0.3 2.2 0.1 1.5 1.3 135.2 0.0 0.2 0.0 0.0 0.3 0.0 1.0 7.9 0.1 16.6 0.2 0.1 3.7 0.0 10.7 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.3 1.8 2.8 0.1 0.0 0.0 0.8 0.0 0.3 0.3 4.8 0.0 0.1 7.2 1.0 0.0 6.0 0.0 0.0 0.0 0.1 1.2 8.6 0.0 0.8 0.8 0.3 0.4 0.4 32.9 7.0 19.8 1.7 2.2 0.5 1.1 1.0 0.1 0.5 1.0 0.7 SLC35C1 "FLJ11320, FUCT1" ENSG00000181830 "Solute carrier family 35 member C1" Q96A29 11 45804072-45813016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 84.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.6;Distal enterocytes: 54.6;Pancreatic endocrine cells: 50.6;Paneth cells: 54.0;Proximal enterocytes: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064001 Enhanced Supported "Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA064001: AB_2685171" "unprognostic (2.62e-2)" "unprognostic (5.16e-2)" "unprognostic (7.82e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (8.22e-2)" "unprognostic (9.40e-2)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "unprognostic (4.09e-2)" "unprognostic (2.73e-1)" "unprognostic (7.68e-2)" "unprognostic (1.83e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.64e-4)" "unprognostic (2.30e-2)" 28.2 7.3 6.6 10.7 6.3 2.4 19.8 7.0 7.0 9.6 6.1 19.8 24.4 8.8 2.3 41.5 7.3 12.2 9.0 6.2 7.2 7.0 84.5 10.2 6.6 8.2 7.9 6.3 13.4 5.6 10.4 15.0 7.7 9.9 14.3 1.6 26.1 5.9 6.8 5.1 24.1 9.9 6.5 8.4 18.5 5.2 8.8 4.5 6.6 6.9 10.0 13.8 14.9 6.3 10.3 25.8 6.3 16.3 19.9 19.8 19.5 22.1 20.1 13.3 14.4 10.7 15.2 10.4 9.9 27.3 19.4 26.0 13.4 13.6 6.5 24.8 14.5 5.9 20.4 20.6 42.6 11.4 16.2 23.8 16.3 9.2 11.1 16.2 17.6 10.3 13.3 13.8 14.4 21.8 5.9 9.0 27.5 39.9 34.6 7.2 10.5 21.5 15.1 25.4 6.0 8.6 16.6 16.3 9.5 6.6 13.7 6.0 25.7 25.0 14.7 46.1 15.6 9.8 26.9 4.9 18.5 14.4 14.2 9.7 11.6 12.5 11.0 11.9 12.3 5.0 18.0 14.7 9.6 3.7 9.3 8.0 1.8 5.6 8.7 8.2 13.0 10.1 6.6 6.3 7.0 7.0 6.2 7.2 8.2 7.9 7.7 6.5 8.8 6.3 5.5 0.0 11.2 2.6 6.2 3.6 8.9 12.7 3.4 1.9 11.1 3.0 50.6 22.8 26.7 5.5 2.1 13.8 6.4 54.6 0.0 18.4 4.9 7.3 6.7 10.6 9.6 3.6 2.0 41.9 14.0 10.5 23.4 11.4 2.5 5.2 6.8 42.2 14.7 3.3 2.1 40.6 4.1 9.3 4.8 6.0 6.5 6.3 1.8 2.8 9.5 2.8 7.2 1.0 2.1 50.6 54.0 5.7 13.6 11.8 58.0 4.7 11.4 1.1 0.0 3.6 9.7 4.0 4.3 12.7 2.4 15.3 6.5 5.7 26.4 20.1 SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.4;Hofbauer cells: 36.5;Kupffer cells: 22.0;Macrophages: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cell line enhanced" "Detected in many" "A-431: 33.8;CAPAN-2: 70.3;hTCEpi: 34.9;hTERT-HME1: 64.8;U-138 MG: 47.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" 4.2 24.2 1.7 16.9 2.6 1.4 4.6 2.4 3.7 2.3 2.1 8.0 9.1 1.0 1.3 13.4 1.2 5.1 1.5 1.9 2.3 0.7 5.9 5.9 5.7 4.3 2.7 1.0 1.2 1.1 0.2 7.4 3.8 2.6 10.2 0.5 78.8 1.4 0.6 20.9 7.7 3.1 3.2 15.8 2.1 1.6 5.2 2.1 0.6 0.9 5.1 11.9 7.7 7.3 33.8 0.1 1.0 0.4 0.6 0.8 0.6 1.6 2.8 1.0 2.5 0.2 70.3 0.4 9.4 0.4 2.5 21.0 0.4 20.9 3.8 0.9 0.6 6.6 1.6 2.4 0.1 0.3 0.9 0.7 34.9 2.6 64.8 2.7 1.7 1.3 0.5 2.2 3.1 0.3 0.3 4.6 1.9 0.2 1.0 0.4 2.7 0.8 1.0 17.6 0.3 0.3 4.8 2.9 2.6 0.5 0.3 1.8 3.7 47.2 1.9 0.7 1.6 1.8 1.5 1.1 1.7 2.4 4.1 0.2 12.3 0.0 0.0 14.1 0.0 0.4 0.0 0.1 5.5 0.1 0.1 0.1 1.3 0.0 19.2 0.2 0.0 5.4 1.7 2.6 2.4 3.7 1.9 2.3 4.3 2.7 3.8 3.2 5.2 7.3 0.7 0.0 0.6 0.3 3.8 0.3 1.4 0.5 1.2 1.5 1.4 1.1 1.1 1.5 1.6 0.0 2.1 0.6 0.7 13.4 0.0 0.1 1.6 1.9 1.4 1.3 0.0 2.7 0.3 0.0 0.8 0.5 0.0 4.9 2.5 0.4 1.8 0.3 36.5 0.0 0.3 0.1 0.0 22.0 1.4 2.2 0.9 22.7 0.0 8.4 7.3 0.3 3.1 1.0 0.2 0.1 3.3 1.2 1.7 1.0 0.0 0.1 0.2 0.8 0.0 0.8 0.6 2.7 1.1 5.7 0.9 3.4 1.2 0.4 0.1 3.2 SLC37A3 DKFZp761N0624 ENSG00000157800 "Solute carrier family 37 member 3" Q8NCC5 7 140293693-140404433 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.39e-1)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.44e-1)" "unprognostic (5.59e-2)" "unprognostic (2.69e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.78e-5)" "unprognostic (1.97e-1)" "unprognostic (2.94e-1)" "unprognostic (3.78e-2)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-2)" "unprognostic (3.31e-1)" "unprognostic (3.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.50e-2)" 19.2 10.2 10.6 10.6 11.5 12.3 21.5 10.9 14.0 30.2 7.4 26.4 14.1 44.0 23.9 11.4 23.4 19.1 12.8 10.8 11.3 15.8 12.8 16.5 9.1 10.3 9.3 20.7 25.7 35.0 17.1 21.8 10.6 14.7 24.5 11.3 23.3 12.7 7.8 13.5 16.4 31.9 8.9 15.7 18.4 7.4 11.7 11.7 21.3 9.9 10.6 22.1 18.3 11.0 18.0 29.9 30.3 53.3 42.7 46.6 36.2 26.3 30.8 17.9 26.6 23.9 38.1 2.7 32.6 24.0 45.8 14.5 18.5 32.0 27.3 40.6 27.1 3.5 7.8 24.1 35.9 0.2 9.7 36.8 32.3 19.0 22.0 31.2 27.9 15.5 18.2 7.3 27.8 34.3 17.5 1.6 44.9 43.2 18.4 9.5 8.1 8.2 34.5 37.0 29.8 36.7 7.3 29.5 29.7 32.3 15.9 1.7 32.0 20.4 14.8 51.8 27.3 14.0 28.4 6.9 21.6 0.2 47.7 7.6 3.6 3.7 6.5 2.0 3.5 2.3 6.9 5.1 3.0 1.7 7.3 5.5 12.3 5.9 1.3 0.9 8.6 3.6 10.6 11.5 10.9 14.0 10.8 11.3 10.3 9.3 10.6 8.9 11.7 11.0 8.5 9.6 12.4 14.4 6.0 15.2 39.8 11.8 8.6 11.4 12.1 8.6 5.1 10.0 16.1 12.9 10.4 17.5 5.8 21.0 1.9 22.3 1.6 24.9 43.8 11.6 21.6 6.1 37.1 26.9 26.4 30.6 19.9 21.3 8.2 15.0 13.2 7.3 4.0 13.5 29.0 22.2 14.2 5.1 9.7 2.3 20.2 3.3 19.6 13.1 7.4 3.6 11.3 26.7 22.4 28.6 14.7 13.5 4.2 31.4 11.2 5.7 18.4 9.0 6.6 15.1 16.9 4.6 5.9 8.5 12.4 13.1 10.6 5.1 18.1 37.4 SLC38A1 "ATA1, NAT2, SAT1" ENSG00000111371 "Solute carrier family 38 member 1" Q9H2H9 12 46183063-46270017 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 443.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 386.1" "Low region specificity" "Detected in all" "HPA039460, HPA052272" Uncertain Supported NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA039460: , HPA052272: AB_2681781" "unprognostic (8.92e-3)" "unprognostic (3.23e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (4.76e-6)" "unprognostic (1.00e-1)" "unprognostic (3.74e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (2.01e-3)" "unprognostic (1.38e-1)" "unprognostic (4.19e-3)" "unprognostic (2.44e-2)" "unprognostic (3.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (3.00e-1)" "unprognostic (5.55e-2)" 8.2 5.3 20.0 38.5 18.6 26.0 81.8 48.2 18.9 13.6 0.6 39.3 16.7 16.4 8.7 26.6 15.5 16.6 44.6 15.3 42.3 20.3 6.4 13.2 64.4 44.1 25.4 9.9 23.8 78.7 19.3 22.5 34.6 29.5 38.5 79.0 20.5 35.6 90.7 30.5 22.9 27.8 48.4 31.9 21.3 1.1 26.8 59.5 42.5 82.4 54.4 23.4 11.2 59.7 77.6 79.2 28.2 104.9 12.4 4.5 142.8 60.6 98.2 27.3 42.7 136.6 74.9 176.3 113.0 74.7 83.6 116.5 94.8 124.5 50.4 109.6 49.8 12.3 127.4 51.2 108.3 126.1 4.5 21.7 186.7 8.2 325.1 67.5 61.6 112.0 65.2 144.2 86.5 96.5 112.7 22.0 104.1 0.1 122.7 99.8 6.9 124.6 105.4 109.8 111.6 77.2 126.2 152.9 71.7 108.0 88.9 91.1 129.8 21.2 19.7 0.6 62.7 136.2 126.5 386.1 67.9 242.2 18.6 1.0 0.8 26.3 51.8 0.2 71.0 50.4 54.1 61.0 34.9 57.8 62.6 57.1 2.4 68.3 0.4 44.3 63.5 46.4 20.0 18.6 48.2 18.9 15.3 42.3 44.1 25.4 34.6 48.4 26.8 59.7 10.3 35.3 44.7 75.4 150.0 97.8 73.8 103.8 30.1 443.5 136.5 64.8 207.5 38.6 61.8 213.3 141.8 106.9 216.3 99.3 3.9 56.3 0.2 78.1 9.8 26.7 40.6 25.6 104.7 46.4 79.3 14.6 19.4 123.7 3.8 30.9 5.7 6.1 12.2 8.4 157.8 73.6 79.3 12.9 76.1 0.3 2.1 23.3 26.6 30.9 13.6 51.4 107.1 94.5 59.7 53.5 52.8 0.7 138.8 66.5 23.6 1.1 29.7 54.2 0.0 62.9 34.5 0.1 0.4 70.3 122.7 185.7 167.9 1.6 93.6 75.4 SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast glandular cells: 307.0;Prostatic glandular cells: 197.9" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" 27.3 25.9 23.3 21.6 28.5 11.6 147.2 28.6 26.1 34.5 48.9 13.9 9.6 56.9 56.2 17.0 63.6 24.2 14.0 20.0 28.8 28.2 16.5 18.9 17.3 28.8 33.6 43.1 37.7 86.5 23.9 31.7 30.6 129.0 13.4 50.2 30.9 114.3 12.7 51.3 8.9 30.2 28.6 15.5 16.4 19.3 26.7 18.5 37.3 16.6 28.4 52.6 16.1 34.2 43.7 54.0 127.1 75.1 131.4 96.6 33.0 116.2 137.3 76.5 88.7 30.3 47.5 47.1 57.3 113.1 53.1 104.1 112.4 109.2 115.5 105.4 40.7 20.6 69.5 44.4 83.2 69.8 49.6 88.7 236.1 116.2 100.5 69.9 11.7 38.6 10.7 92.1 108.9 67.0 69.0 15.6 30.6 24.0 30.4 70.6 72.8 61.4 84.4 145.2 132.8 116.8 143.5 41.5 200.6 52.1 56.7 32.4 18.9 184.9 30.5 35.5 59.2 85.9 90.0 35.7 64.0 48.3 99.8 29.2 13.3 31.2 16.3 19.7 19.7 16.7 13.8 14.7 16.4 17.3 12.0 17.7 10.2 18.1 19.4 33.6 17.0 14.2 23.3 28.5 28.6 26.1 20.0 28.8 28.8 33.6 30.6 28.6 26.7 34.2 13.3 38.5 18.7 8.8 22.5 45.9 58.2 79.6 59.2 41.5 307.0 132.2 19.6 10.0 66.4 42.3 33.3 6.6 36.7 4.0 1.9 53.1 21.3 37.1 76.1 12.9 25.6 4.6 13.0 37.8 56.7 45.6 9.2 73.8 23.5 18.9 8.9 11.0 20.4 23.5 23.9 7.4 38.7 20.1 30.0 18.1 37.3 26.0 67.6 1.9 25.7 38.2 10.3 34.2 36.5 39.5 1.9 47.8 24.4 197.9 2.7 13.6 44.3 41.3 39.5 40.4 38.6 43.9 27.8 32.6 74.4 23.8 23.2 23.0 5.7 69.3 SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 780.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 1441.0;SiHa: 1287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" 103.3 105.6 130.5 46.7 138.0 122.0 108.9 140.1 160.4 101.6 115.6 60.6 51.5 97.2 65.3 112.9 94.0 35.8 52.0 123.1 133.3 171.2 71.9 117.8 34.9 138.4 132.6 93.0 109.7 189.7 65.3 55.4 134.0 100.8 23.1 22.8 110.6 41.9 122.3 127.1 79.7 33.8 135.8 77.4 90.2 65.1 154.5 30.1 110.2 26.0 28.8 77.7 95.1 130.6 155.5 675.7 60.2 213.2 89.7 69.7 596.7 267.5 106.2 154.0 126.3 643.3 293.0 173.9 290.5 185.4 284.5 540.0 123.1 588.9 84.3 319.3 114.0 117.5 422.4 299.2 825.7 136.0 169.4 144.9 1441.0 175.3 528.8 46.2 83.6 380.7 232.9 347.4 95.1 792.6 149.8 181.3 106.9 222.5 214.2 153.8 92.7 341.8 113.9 84.0 112.5 53.5 1287.0 499.6 948.5 121.2 161.5 182.6 146.2 138.3 200.0 204.4 195.5 436.0 556.1 561.2 135.0 225.1 418.0 37.8 149.0 49.7 117.9 147.4 157.7 58.3 107.3 122.1 88.6 72.1 90.1 97.2 31.2 90.3 123.9 304.7 112.5 186.3 130.5 138.0 140.1 160.4 123.1 133.3 138.4 132.6 134.0 135.8 154.5 130.6 97.8 48.1 37.3 91.1 78.8 218.1 244.2 321.7 399.5 58.4 124.2 120.8 13.4 30.0 141.1 49.7 66.7 222.5 136.2 109.6 33.2 161.9 31.5 122.0 96.3 149.2 84.3 117.7 16.9 151.1 143.7 102.9 71.4 179.7 84.3 43.2 99.2 27.0 202.9 53.8 25.1 60.4 223.8 54.1 140.9 28.9 30.4 141.5 224.1 29.0 104.7 188.4 40.2 21.1 11.3 130.6 58.7 30.5 140.9 156.9 120.7 227.4 63.4 61.2 6.6 71.8 114.6 21.3 31.9 160.7 150.6 780.7 118.1 52.4 60.7 194.9 SLC43A1 "PB39, POV1, R00504" ENSG00000149150 "Solute carrier family 43 member 1" O75387 11 57484534-57515780 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 128.6;pancreas: 233.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 47.1;Erythroid cells: 82.9;Exocrine glandular cells: 35.4;Hepatocytes: 138.2" "Cancer enhanced" "Detected in all" "liver cancer: 45.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.7;NB-4: 74.3;U-937: 70.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018813, HPA018826" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Vesicles, Plasma membrane" "HPA018813: AB_1857164, HPA018826: AB_1857165" "unprognostic (3.04e-1)" "unprognostic (1.15e-1)" "unprognostic (9.19e-2)" "prognostic favorable (3.19e-4)" "unprognostic (2.51e-2)" "unprognostic (5.48e-2)" "unprognostic (2.32e-1)" "unprognostic (6.71e-3)" "unprognostic (1.63e-1)" "unprognostic (3.12e-2)" "unprognostic (6.06e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.97e-5)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (7.30e-2)" 13.9 10.7 3.6 4.7 4.2 35.7 11.1 2.7 5.0 13.1 2.7 15.7 8.7 12.6 10.3 4.4 13.5 18.2 8.6 3.6 2.8 7.3 128.6 9.9 7.4 3.8 3.2 20.3 233.2 1.8 4.4 6.3 3.5 12.8 9.4 1.3 13.8 6.2 17.1 18.8 9.2 8.7 2.7 8.5 30.4 3.4 3.4 2.1 12.7 9.1 6.6 16.2 9.9 3.9 1.1 1.7 1.8 20.3 25.7 18.8 0.2 10.4 13.8 3.0 7.6 6.5 2.8 59.5 2.7 7.9 3.9 1.0 18.1 1.2 3.7 2.8 4.6 30.9 0.5 62.7 33.7 54.3 7.2 23.8 4.4 5.2 23.2 7.3 13.4 34.7 43.9 10.7 3.8 2.3 0.5 74.3 6.6 27.0 13.6 51.0 9.8 27.2 0.5 0.1 23.5 3.6 1.9 0.3 23.8 0.5 1.6 27.3 5.5 3.1 7.1 26.2 1.7 12.1 4.3 35.3 1.5 70.6 4.2 11.1 6.2 0.7 10.9 2.4 9.2 2.9 4.9 7.7 8.4 1.5 4.9 6.9 0.5 7.5 0.2 1.9 9.5 5.5 3.6 4.2 2.7 5.0 3.6 2.8 3.8 3.2 3.5 2.7 3.4 3.9 4.4 0.0 7.3 1.6 3.3 7.0 1.6 0.0 3.4 5.7 1.8 2.4 6.8 47.1 0.6 0.0 0.0 0.2 3.6 3.1 3.9 3.4 21.5 5.3 6.0 4.7 6.0 82.9 3.5 35.4 0.4 10.9 4.6 13.4 3.8 1.3 15.4 138.2 7.4 0.0 1.4 8.8 0.0 8.1 2.9 14.8 15.5 3.2 5.4 5.6 1.3 0.2 5.2 4.0 0.6 11.1 2.9 7.9 6.2 3.2 0.3 0.1 0.7 0.4 6.6 6.4 7.7 0.7 1.5 0.3 3.7 0.1 6.4 2.9 9.0 0.9 SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.0;prostate: 83.0;stomach 1: 83.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 546.0;Exocrine glandular cells: 213.4;Intestinal goblet cells: 327.8;Paneth cells: 299.3;Proximal enterocytes: 267.7;Respiratory ciliated cells: 406.7;Undifferentiated cells: 259.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" 0.8 8.2 0.0 2.5 0.0 1.0 5.3 0.0 0.0 22.4 0.0 132.0 100.8 5.9 2.5 2.0 46.9 18.8 0.0 0.0 0.0 32.1 0.4 14.9 0.1 0.3 0.1 1.6 8.9 0.0 16.1 3.5 0.1 83.0 30.3 0.0 42.6 3.9 0.0 1.1 86.8 2.9 0.0 1.6 83.4 0.7 0.0 0.2 1.9 0.0 0.7 11.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 3.7 22.4 36.0 0.0 3.8 0.5 23.0 71.4 0.6 0.3 14.6 6.1 0.4 38.6 180.2 66.2 0.0 0.3 0.5 546.0 3.9 111.2 2.3 127.4 8.9 6.2 46.7 0.0 0.1 213.4 0.5 2.4 208.5 67.5 2.5 1.1 0.4 0.0 0.5 0.0 0.1 327.8 91.6 0.0 0.0 3.2 1.5 2.5 0.0 0.0 1.6 0.7 0.0 0.0 0.0 184.0 299.3 0.4 0.3 142.0 267.7 61.5 406.7 0.6 0.0 0.8 11.9 0.2 0.2 0.5 0.4 0.7 2.3 5.5 259.6 139.4 SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "prostate: 306.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 19.9;granulocytes: 119.2;Oligodendrocytes: 47.1;Prostatic glandular cells: 67.2" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.5" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.5" "Cell line enriched" "Detected in many" 29 "HMC-1: 834.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" 1.4 3.6 6.7 3.2 19.5 0.8 1.6 17.6 13.4 3.7 1.9 4.8 4.6 1.7 0.5 1.6 2.1 3.8 1.5 8.0 10.3 2.1 11.2 3.4 2.7 25.1 17.3 2.7 0.8 0.3 4.7 0.5 21.8 306.4 3.2 0.1 2.8 0.6 5.6 1.5 4.8 1.0 12.6 12.4 16.8 1.4 16.6 0.5 1.0 2.3 0.8 2.8 1.1 44.7 9.7 3.0 2.8 2.7 0.0 0.1 2.2 1.3 0.3 3.3 2.7 7.1 18.0 2.7 4.6 0.3 3.0 3.5 1.6 3.3 0.5 3.9 2.9 29.0 0.6 2.0 1.9 5.0 834.2 0.3 1.1 2.3 0.0 2.2 9.4 4.5 4.9 1.7 1.4 2.3 0.8 8.5 12.2 16.7 10.7 1.0 4.1 1.5 3.7 13.7 1.2 2.9 1.5 20.6 3.9 2.3 4.7 1.4 9.6 1.4 9.5 3.5 7.1 0.4 0.6 0.4 1.8 1.5 7.1 40.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 19.5 17.6 13.4 8.0 10.3 25.1 17.3 21.8 12.6 16.6 44.7 0.2 0.0 3.2 1.0 4.0 0.0 1.0 0.6 0.0 0.4 1.5 1.8 2.0 2.8 1.0 1.8 0.0 0.5 0.1 5.7 0.0 1.7 0.2 1.9 0.2 1.7 0.0 3.4 0.2 0.5 0.1 0.7 19.9 0.2 119.2 0.2 0.7 6.6 1.9 0.0 0.3 6.9 2.0 1.0 0.3 0.4 1.8 2.0 0.0 0.0 0.6 0.1 0.0 2.0 47.1 3.9 8.0 1.5 0.3 67.2 0.9 1.8 3.2 0.1 6.6 0.1 0.8 0.0 2.6 0.4 0.1 0.0 0.9 0.2 6.7 0.9 SLC47A2 "FLJ31196, MATE2, MATE2-K" ENSG00000180638 "Solute carrier family 47 member 2" Q86VL8 17 19678288-19718979 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.3;choroid plexus: 39.6;kidney: 55.8" "Cell type enriched" "Detected in some" 4 "Proximal tubular cells: 91.3" "Cancer enhanced" "Detected in some" "glioma: 2.6;renal cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 2.1" "Not detected" "Not detected" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (4.52e-3)" "unprognostic (8.28e-3)" "unprognostic (1.54e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (8.95e-4)" "unprognostic (5.22e-2)" "unprognostic (2.72e-1)" "unprognostic (1.99e-2)" "unprognostic (3.29e-2)" "unprognostic (1.51e-1)" "unprognostic (1.36e-3)" "unprognostic (7.77e-2)" "unprognostic (1.04e-3)" "unprognostic (4.33e-2)" "unprognostic (1.61e-1)" "unprognostic (6.44e-2)" "unprognostic (5.71e-2)" 0.1 0.2 2.5 0.0 2.1 0.0 0.2 2.0 1.5 0.1 39.6 0.0 0.0 0.1 6.7 0.4 10.0 0.0 0.1 3.5 6.4 55.8 0.0 0.0 0.0 11.6 22.3 0.1 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.6 0.4 0.2 1.1 2.3 0.3 0.1 8.4 0.0 0.0 0.0 5.0 0.0 0.2 0.2 0.0 0.0 0.1 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.1 2.0 1.5 3.5 6.4 11.6 22.3 11.5 8.4 5.0 4.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.6 0.0 0.0 0.9 0.7 0.0 0.2 5.5 0.0 0.1 0.0 0.2 5.9 0.0 0.6 20.9 0.4 0.1 0.0 0.0 3.3 0.0 0.0 0.5 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.0 2.0 0.0 0.0 0.7 0.3 0.9 0.0 1.9 0.0 1.3 0.0 2.0 1.4 0.1 0.0 0.0 0.0 0.8 1.7 91.3 2.5 0.5 0.0 3.5 0.1 0.6 0.8 1.0 0.3 0.0 0.6 0.0 0.2 0.2 SLC4A4 "hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5" ENSG00000080493 "Solute carrier family 4 member 4" Q9Y6R1 4 71062667-71572087 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 119.5;pancreas: 260.3" "Cell type enhanced" "Detected in many" "Astrocytes: 819.1;Cholangiocytes: 133.0;Distal enterocytes: 282.9;Ductal cells: 129.2;Proximal tubular cells: 211.0" "Group enriched" "Detected in many" 5 "glioma: 23.9;pancreatic cancer: 22.5;prostate cancer: 47.4;renal cancer: 19.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 13.0;fHDF/TERT166: 6.1;HBF TERT88: 5.7;hTERT-RPE1: 6.0;RPTEC TERT1: 15.4;U-138 MG: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022493, HPA035628, HPA035629, HPA079220" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022493: , HPA035628: AB_2674708, HPA035629: AB_2674709, HPA079220: " "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "prognostic favorable (7.69e-4)" "unprognostic (5.32e-2)" "unprognostic (1.01e-1)" "unprognostic (5.09e-2)" "unprognostic (4.24e-2)" "unprognostic (7.49e-2)" "unprognostic (1.46e-1)" "unprognostic (9.22e-3)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.18e-4)" "unprognostic (7.00e-2)" "unprognostic (2.92e-1)" "unprognostic (2.05e-3)" "unprognostic (2.04e-1)" 5.1 0.7 30.0 2.2 43.6 0.5 1.0 47.0 32.5 11.5 0.0 41.1 54.3 0.4 0.3 1.2 0.9 29.4 6.2 21.5 37.9 119.5 21.7 6.9 0.2 38.6 28.0 0.8 260.3 17.2 5.8 2.7 24.8 34.7 41.2 5.1 2.5 1.1 2.2 0.1 14.6 1.7 38.2 0.8 18.6 0.5 38.5 3.5 22.0 3.5 0.0 4.5 0.4 33.2 0.0 3.5 1.0 0.0 0.0 0.0 0.1 13.0 1.9 2.2 1.6 0.0 0.1 0.0 0.1 6.1 0.5 0.0 0.2 0.0 5.7 0.0 1.7 0.9 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 6.0 0.0 0.7 0.0 0.5 1.2 0.0 4.8 0.2 0.1 0.2 0.0 0.0 0.0 0.9 15.4 4.1 0.9 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.0 7.7 0.7 5.5 0.6 0.0 0.0 0.0 5.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 30.0 43.6 47.0 32.5 21.5 37.9 38.6 28.0 24.8 38.2 38.5 33.2 1.5 3.2 37.1 819.1 2.2 0.0 4.3 3.2 0.6 3.2 0.9 0.3 24.0 133.0 31.1 25.8 0.0 0.3 7.2 282.9 15.6 129.2 11.5 2.8 0.5 1.3 8.5 4.0 51.4 24.2 0.1 4.9 33.1 5.8 1.3 0.6 3.9 35.8 0.2 0.0 93.4 65.6 2.0 0.6 0.2 1.5 0.0 2.3 1.8 34.7 1.0 3.9 1.0 29.1 3.7 16.2 60.8 0.0 1.7 40.8 31.8 211.0 10.4 1.5 6.6 1.0 6.2 0.1 1.0 5.5 0.0 0.3 6.8 2.4 68.1 12.3 SLC51B OSTbeta ENSG00000186198 "Solute carrier family 51 subunit beta" Q86UW2 15 65045387-65053397 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 41.8;intestine: 107.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 354.6;Paneth cells: 145.1;Proximal enterocytes: 721.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 18.5;EFO-21: 11.9;Hep G2: 15.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008398, HPA008533" Enhanced Approved Vesicles,Mitochondria No NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria Vesicles "HPA008398: , HPA008533: AB_1854824" "unprognostic (6.18e-2)" "unprognostic (6.75e-3)" "unprognostic (1.66e-1)" "unprognostic (1.31e-2)" "unprognostic (5.88e-2)" "unprognostic (9.49e-2)" "unprognostic (9.77e-3)" "unprognostic (1.81e-2)" "unprognostic (3.35e-2)" "unprognostic (2.76e-1)" "unprognostic (2.24e-1)" "unprognostic (4.34e-2)" "prognostic favorable (8.46e-5)" "unprognostic (5.87e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.17e-2)" 0.7 1.1 5.8 3.5 5.5 0.8 0.3 4.0 3.9 41.8 0.0 41.9 86.9 3.0 0.3 2.4 3.6 2.8 2.3 3.8 6.5 19.5 2.2 6.1 0.6 7.3 10.9 1.1 0.3 0.0 0.4 0.6 7.7 2.7 29.4 0.7 1.0 0.6 1.0 0.8 107.1 1.7 6.5 0.8 0.8 9.6 11.8 0.0 0.7 0.0 0.0 1.5 0.9 4.2 0.0 1.5 0.2 0.8 0.0 0.1 0.4 0.0 0.0 0.2 0.0 18.5 0.0 0.1 11.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 15.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.4 0.1 0.4 0.4 0.1 0.4 0.0 0.0 0.9 0.4 0.0 0.6 0.5 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.5 4.0 3.9 3.8 6.5 7.3 10.9 7.7 6.5 11.8 4.2 0.0 0.0 1.1 0.3 1.3 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.1 0.0 354.6 13.7 0.0 60.8 10.4 0.2 1.2 1.8 2.7 0.0 0.0 0.0 0.5 0.0 1.9 4.5 0.0 0.4 1.8 0.1 0.0 0.0 23.0 0.0 0.3 0.0 14.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 145.1 0.0 0.0 0.0 721.4 73.3 15.6 0.0 6.6 1.0 0.4 27.9 0.5 0.0 0.0 0.1 0.6 0.1 45.8 0.0 SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 185.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.3;Cardiomyocytes: 10.8;Cytotrophoblasts: 14.3;dendritic cells: 9.6;Extravillous trophoblasts: 14.6;Hofbauer cells: 36.1;Syncytiotrophoblasts: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA051666: AB_2681567" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (6.45e-2)" "unprognostic (3.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.34e-1)" "unprognostic (1.40e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-2)" 57.1 24.4 32.1 14.4 30.4 38.3 53.4 25.3 40.0 30.3 33.5 38.0 9.7 27.4 5.6 46.5 27.0 14.5 32.4 37.0 26.9 49.0 185.4 37.4 18.1 34.5 31.2 21.6 33.8 11.5 23.8 10.3 31.9 32.2 7.5 7.2 38.9 9.9 83.9 55.5 24.5 8.5 29.1 34.4 25.6 77.0 34.3 12.3 68.4 25.9 8.9 26.3 34.2 29.2 34.8 11.7 11.9 23.0 26.0 16.6 16.0 22.4 15.1 17.6 16.6 15.6 18.5 14.6 8.5 20.4 10.3 34.8 16.2 23.8 4.7 44.3 23.8 18.2 16.7 42.6 30.9 44.2 44.5 18.6 23.2 16.2 6.2 9.0 15.3 15.8 6.9 11.6 9.2 26.6 22.1 47.6 3.9 4.7 31.5 38.7 12.4 24.6 12.0 24.4 34.8 15.7 16.9 21.3 25.6 3.1 12.7 48.0 19.4 26.8 27.2 14.3 17.2 5.8 10.0 18.8 20.5 53.2 12.1 0.3 1.7 2.0 0.6 1.7 0.4 0.8 0.7 0.3 1.9 0.6 0.9 1.1 1.2 1.0 1.6 3.5 0.8 0.8 32.1 30.4 25.3 40.0 37.0 26.9 34.5 31.2 31.9 29.1 34.3 29.2 20.3 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 14.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 14.6 4.6 0.0 0.0 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 20.8 2.0 0.0 0.0 0.0 SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.0;Distal enterocytes: 382.0;Proximal enterocytes: 235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 155.8;AN3-CA: 151.3;SK-BR-3: 156.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" 31.6 66.6 77.2 9.0 99.4 34.5 23.9 77.8 80.0 17.5 39.9 73.5 51.3 32.4 13.0 54.6 17.3 31.3 130.4 76.8 82.1 81.4 4.5 9.2 1.9 89.0 90.5 12.4 20.0 45.6 21.4 36.2 76.9 31.3 30.5 34.7 52.3 35.9 166.6 45.9 75.9 20.7 71.3 13.1 30.8 38.5 87.6 11.9 8.2 75.5 3.0 41.2 36.5 116.6 155.8 6.7 39.5 151.3 14.7 9.9 10.2 22.2 37.7 28.7 35.5 20.1 2.1 0.2 17.0 27.9 33.6 54.3 85.3 78.0 17.0 2.7 83.3 0.6 50.6 59.7 50.0 1.2 10.1 20.9 16.5 27.3 103.3 50.7 14.9 0.9 37.3 2.4 15.7 9.3 0.8 3.6 47.0 30.9 67.0 7.6 5.2 2.1 30.8 29.5 56.0 64.2 33.8 156.8 107.9 9.8 30.9 23.9 14.1 45.2 73.1 58.2 66.5 5.2 3.0 1.8 105.5 4.5 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 77.2 99.4 77.8 80.0 76.8 82.1 89.0 90.5 76.9 71.3 87.6 116.6 5.9 0.0 1.9 14.0 2.7 23.2 14.3 91.1 13.1 142.0 19.6 18.4 106.9 21.5 55.6 5.5 110.5 15.3 2.8 382.0 3.9 4.6 1.5 21.4 38.9 6.5 25.9 23.4 8.2 22.2 37.7 8.8 6.1 16.1 4.5 14.4 3.9 0.9 4.9 119.5 9.9 44.2 38.7 1.9 5.7 3.7 9.0 4.1 24.9 2.8 3.2 19.0 0.0 9.0 23.7 47.5 101.1 8.2 0.8 28.3 235.8 53.3 31.3 49.3 32.9 15.6 19.0 2.9 3.9 16.9 15.6 90.8 2.9 1.5 20.7 18.6 SLC7A10 asc-1 ENSG00000130876 "Solute carrier family 7 member 10" Q9NS82 19 33208664-33225850 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 31.8;brain: 12.7;breast: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 40.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.9;HHSteC: 1.1;HSkMC: 1.6;THP-1: 3.9;U-2 OS: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041884, HPA057036" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli" "HPA041884: AB_10794494, HPA057036: AB_2683317" "unprognostic (1.85e-2)" "unprognostic (1.69e-3)" "unprognostic (2.79e-2)" "unprognostic (1.79e-6)" "unprognostic (1.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (4.98e-3)" "unprognostic (4.64e-2)" "unprognostic (1.96e-1)" "unprognostic (3.28e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-2)" "unprognostic (1.34e-3)" "unprognostic (8.91e-2)" "unprognostic (3.47e-1)" "unprognostic (2.18e-2)" 31.8 0.3 7.9 0.1 9.7 0.0 12.7 10.1 11.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.3 9.2 0.5 0.0 0.0 0.2 8.5 12.4 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.5 0.8 0.0 0.1 0.2 0.5 0.0 6.0 0.0 0.1 0.5 12.7 0.0 0.5 0.4 0.3 0.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 9.7 10.1 11.1 7.3 9.2 8.5 12.4 8.4 6.0 12.7 5.1 0.1 0.0 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 2.4 0.0 9.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLC7A13 "AGT-1, XAT2" ENSG00000164893 "Solute carrier family 7 member 13" Q8TCU3 8 86214063-86321146 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 234 "kidney: 42.0" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.34e-1)" "unprognostic (2.62e-1)" "unprognostic (1.12e-1)" "unprognostic (2.96e-5)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.0" "Cell type enhanced" "Detected in many" "Microglial cells: 55.3;Syncytiotrophoblasts: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Plasma membrane" "HPA050713: AB_2681218" "unprognostic (6.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-2)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (1.89e-3)" "unprognostic (7.82e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.84e-4)" 35.3 8.8 1.7 15.5 1.9 8.4 26.9 6.5 3.3 5.5 17.3 8.3 3.9 5.8 11.5 4.5 8.6 4.4 18.5 3.3 2.2 5.9 2.0 10.9 18.6 1.0 1.3 2.7 3.8 2.5 9.6 18.6 1.5 6.2 11.1 5.0 7.3 5.2 75.0 10.2 12.0 7.7 1.0 10.7 6.6 5.1 2.2 37.6 16.7 26.9 21.5 6.8 4.8 1.1 22.6 22.1 16.3 16.8 46.9 27.6 42.9 24.9 18.7 36.9 30.6 97.9 16.2 43.7 19.8 33.4 10.9 33.1 32.0 32.2 39.7 9.5 22.9 23.8 47.3 31.0 7.7 28.2 20.3 19.3 26.1 27.5 13.5 11.4 25.3 21.0 35.1 7.3 20.5 11.7 36.4 19.3 12.4 14.6 8.1 45.0 10.2 36.0 12.0 19.6 23.7 13.5 75.7 20.8 6.8 13.4 30.9 13.3 38.4 24.6 19.0 20.5 32.8 16.7 33.5 50.3 15.6 20.1 17.2 3.4 3.2 2.8 4.3 1.7 5.4 6.8 6.6 4.3 3.6 6.3 11.7 6.7 6.1 7.1 1.4 16.8 3.1 1.5 1.7 1.9 6.5 3.3 3.3 2.2 1.0 1.3 1.5 1.0 2.2 1.1 8.5 41.7 18.8 12.4 18.4 19.6 9.3 8.5 13.6 6.1 5.9 4.8 19.9 2.8 4.9 18.4 37.5 25.1 23.3 7.3 0.0 3.3 5.5 10.7 16.8 12.0 2.4 2.1 39.3 4.0 2.5 12.8 4.1 3.3 4.5 1.8 6.8 1.4 14.6 10.1 40.3 10.5 4.1 8.5 12.1 18.3 5.9 9.9 10.6 55.3 10.0 1.8 14.4 13.0 10.7 5.6 5.9 3.8 16.0 8.0 2.5 0.6 10.4 2.7 0.0 10.8 7.2 17.3 10.9 6.7 21.9 47.9 23.5 4.3 7.8 2.6 SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 131.6;kidney: 300.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 216.5;Kupffer cells: 410.6;Macrophages: 146.2;monocytes: 164.0;Proximal enterocytes: 423.1;Proximal tubular cells: 327.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 299.9;intermediate monocyte: 410.0;non-classical monocyte: 457.1" "Lineage enriched" "Detected in many" 5 "monocytes: 457.1" "Group enriched" "Detected in many" 4 "BEWO: 217.2;CACO-2: 385.7;OE19: 329.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" 15.1 9.0 3.1 37.4 3.2 19.7 6.8 3.8 7.5 7.3 4.3 13.8 107.0 5.3 2.0 3.7 7.8 17.0 5.1 2.8 3.8 300.6 16.4 54.1 29.1 6.9 4.7 2.1 5.2 78.4 1.4 18.2 6.4 3.5 15.0 1.0 5.4 2.8 2.0 3.2 131.6 15.6 5.1 56.8 8.6 32.8 7.1 9.6 4.6 2.8 25.2 14.7 4.1 8.1 0.2 11.2 1.2 0.5 1.9 3.7 217.2 2.2 16.3 0.4 1.4 385.7 34.4 17.0 72.2 1.4 1.2 13.3 0.1 0.0 0.6 0.6 0.2 0.9 0.4 3.7 9.1 1.9 1.6 7.1 1.0 1.0 0.5 1.8 25.3 1.5 0.1 12.8 2.9 0.6 0.4 1.7 3.6 329.0 0.1 2.9 35.5 9.8 0.8 1.3 0.4 0.8 0.6 0.5 2.5 9.4 0.4 8.3 1.3 0.8 1.7 0.6 0.5 2.7 0.9 8.9 0.9 0.8 0.2 0.2 299.9 1.1 0.5 410.0 0.4 19.1 0.2 0.2 99.5 13.8 0.7 0.4 36.5 0.3 457.1 3.4 0.9 155.1 3.1 3.2 3.8 7.5 2.8 3.8 6.9 4.7 6.4 5.1 7.1 8.1 5.3 12.8 7.1 2.0 14.3 1.0 0.2 6.7 1.8 0.2 0.5 1.7 0.9 67.2 5.6 3.7 0.0 1.2 5.7 3.0 11.7 8.2 61.1 1.7 1.2 5.0 1.2 0.0 0.6 6.4 5.2 4.4 2.6 0.4 1.3 0.7 16.1 3.0 216.5 0.0 1.4 7.2 2.0 410.6 16.8 11.8 3.7 146.2 5.4 20.6 164.0 0.4 4.1 0.0 0.8 8.9 12.5 0.0 20.1 0.1 423.1 327.6 9.2 1.3 6.6 0.8 1.4 17.8 2.2 0.4 0.4 1.8 2.7 38.8 6.4 0.1 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6;lymphoid tissue: 17.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.1;Horizontal cells: 16.8;Inhibitory neurons: 12.2;Oligodendrocyte precursor cells: 7.1;Spermatocytes: 17.2;Theca cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041004, HPA041329" Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Plasma membrane" "HPA041004: AB_10794433, HPA041329: AB_10794373" "unprognostic (8.90e-2)" "unprognostic (9.70e-2)" "unprognostic (3.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (5.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-3)" "unprognostic (4.84e-2)" "unprognostic (9.85e-11)" "unprognostic (9.21e-2)" "unprognostic (1.95e-1)" "unprognostic (8.12e-3)" "unprognostic (9.07e-2)" 0.9 0.6 4.2 0.3 6.6 0.1 1.0 5.4 6.5 0.8 2.5 0.5 0.4 0.4 1.0 0.2 0.5 0.6 1.6 4.6 3.9 0.8 0.2 1.4 0.8 4.8 4.1 1.2 0.6 0.1 0.8 0.6 5.3 0.9 0.3 1.2 0.8 0.3 1.8 1.5 0.5 0.1 3.4 17.4 0.5 3.2 4.2 0.1 0.8 0.7 0.4 0.4 0.5 4.0 0.3 2.9 2.6 0.9 4.7 3.2 0.3 1.1 4.1 2.4 2.2 0.1 2.0 0.0 0.6 1.2 1.2 0.1 0.6 0.4 1.0 0.8 0.8 2.1 0.5 0.7 0.5 1.0 4.7 3.8 1.0 1.5 0.2 4.5 1.0 0.9 0.5 1.3 1.6 1.7 0.0 0.2 1.5 0.2 0.2 0.0 0.5 0.7 0.4 0.5 1.6 0.9 2.4 0.1 1.2 0.6 1.1 0.2 0.8 6.4 0.9 1.1 0.4 2.4 0.5 1.3 4.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.2 6.6 5.4 6.5 4.6 3.9 4.8 4.1 5.3 3.4 4.2 4.0 0.6 3.2 2.8 4.2 0.4 0.6 0.2 0.1 1.2 3.4 1.8 1.3 1.5 1.5 0.2 0.0 0.0 0.3 0.1 0.5 0.0 0.3 1.8 0.2 0.8 0.8 1.2 0.0 11.1 0.2 0.1 0.7 0.0 0.9 0.0 0.9 1.4 0.0 0.1 16.8 12.2 0.3 0.0 0.0 0.4 0.7 0.3 0.5 0.0 1.9 0.6 0.3 0.0 7.1 2.6 0.5 0.1 2.2 0.0 0.5 0.2 0.0 0.7 0.9 0.0 0.6 1.4 17.2 4.6 0.3 0.9 0.0 0.3 6.8 0.3 0.2 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SLFN12L ENSG00000205045 "Schlafen family member 12 like" Q6IEE8 17 35464249-35487857 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.1" "Group enriched" "Detected in some" 8 "dendritic cells: 16.0;NK-cells: 42.2;T-cells: 31.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 3.6" "Group enriched" "Detected in many" 6 "granulocytes: 1.0;NK-cells: 3.6;T-cells: 1.9" "Cell line enhanced" "Detected in some" "HDLM-2: 9.7;Karpas-707: 5.5" HPA024447 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024447: AB_1856614" "unprognostic (1.93e-3)" "unprognostic (2.10e-4)" "unprognostic (3.77e-2)" "unprognostic (2.67e-2)" "unprognostic (8.18e-3)" "unprognostic (2.98e-5)" "unprognostic (4.59e-3)" "unprognostic (2.75e-2)" "unprognostic (6.82e-2)" "unprognostic (1.67e-2)" "unprognostic (9.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.25e-6)" "unprognostic (2.30e-1)" "unprognostic (3.88e-2)" "unprognostic (7.02e-2)" "unprognostic (8.88e-3)" 0.6 0.3 0.9 2.4 0.9 3.0 0.6 2.5 1.8 0.5 0.9 0.6 1.7 0.5 0.3 0.3 0.3 1.0 0.2 0.7 0.4 0.3 0.6 1.3 3.0 0.3 0.0 0.4 0.3 0.1 0.0 0.2 0.3 0.3 0.8 0.8 0.9 0.2 0.5 0.6 1.5 0.4 0.0 3.1 1.2 0.3 0.5 1.0 0.4 0.3 2.2 0.7 0.1 1.5 0.5 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.6 1.4 0.1 0.3 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.7 9.7 0.1 1.3 0.8 0.1 0.0 0.3 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.3 5.5 0.1 0.0 0.4 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.3 0.2 0.2 0.1 0.4 0.1 0.1 0.1 0.0 2.0 0.6 0.3 1.2 0.5 0.2 2.0 2.0 0.1 0.2 0.3 0.5 1.0 0.3 1.0 1.9 0.0 0.8 0.3 0.8 1.4 0.2 0.3 1.0 1.0 0.9 3.6 0.1 0.2 0.5 0.4 0.9 0.9 2.5 1.8 0.7 0.4 0.3 0.0 0.3 0.0 0.5 1.5 3.5 3.2 2.7 0.0 1.5 0.3 0.6 0.4 0.0 0.0 0.3 0.3 1.3 1.5 0.7 0.0 0.0 0.0 16.0 0.0 0.0 0.2 0.8 0.5 0.2 1.4 0.0 0.4 0.0 0.0 0.0 0.5 1.5 0.3 1.3 0.1 0.4 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.4 0.1 0.0 1.1 0.0 1.0 0.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.2 0.0 0.0 0.5 0.7 0.4 0.0 0.3 0.1 0.0 31.7 0.1 0.1 0.2 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SMAD7 "MADH7, MADH8" ENSG00000101665 "SMAD family member 7" O15105 18 48919853-48952052 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 54.5;Distal enterocytes: 56.6;Hepatic stellate cells: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.1;eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026212, HPA028897" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "CAB026212: , HPA028897: AB_10600811" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (8.15e-2)" "unprognostic (5.35e-1)" "unprognostic (2.76e-1)" "unprognostic (6.02e-2)" "unprognostic (2.37e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-1)" "unprognostic (2.09e-1)" "unprognostic (1.91e-1)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-2)" "unprognostic (4.44e-1)" 17.9 5.9 7.1 8.6 7.3 17.8 14.5 12.0 7.3 17.4 9.6 12.7 10.3 11.2 2.9 4.8 8.2 10.2 46.1 5.4 5.1 11.6 8.6 21.9 5.8 10.9 8.7 7.5 5.3 12.3 6.6 18.9 8.5 11.3 11.9 3.2 6.3 8.6 10.7 8.3 15.0 9.3 10.0 5.9 12.5 1.3 7.9 3.7 16.6 6.7 5.2 13.3 12.2 8.4 3.7 2.8 2.8 8.3 14.3 5.0 21.1 18.6 7.1 6.5 3.1 1.0 5.3 0.3 32.2 13.1 6.0 19.2 6.1 5.8 3.6 38.4 9.4 0.3 10.5 6.9 2.1 6.9 18.6 5.1 4.8 7.8 7.8 32.2 1.1 0.6 6.6 25.9 9.1 1.2 0.0 1.9 17.3 27.7 1.1 2.1 2.5 9.0 9.1 4.2 4.8 10.3 8.0 3.5 6.6 21.2 3.3 5.6 17.3 18.5 9.9 5.3 16.5 13.4 7.1 2.0 8.1 4.9 3.1 4.1 0.1 5.6 0.8 0.5 0.6 0.1 0.8 0.7 0.1 0.0 0.2 0.5 0.0 1.7 0.1 0.0 1.2 0.2 7.1 7.3 12.0 7.3 5.4 5.1 10.9 8.7 8.5 10.0 7.9 8.4 30.4 54.5 9.4 3.9 7.0 12.9 3.5 7.2 14.2 6.1 14.7 10.3 9.7 1.5 11.2 11.0 6.2 9.9 43.7 56.6 9.8 14.4 0.2 43.2 30.5 25.0 12.7 0.0 6.5 13.9 3.3 15.5 8.2 45.9 18.9 4.0 71.4 3.1 8.9 0.0 5.0 19.1 2.0 23.3 8.9 1.1 1.5 14.7 0.0 19.7 8.2 1.4 11.3 5.5 16.3 31.5 17.3 3.4 13.8 3.0 28.7 7.1 3.3 2.5 6.6 11.3 14.1 0.1 0.6 14.2 11.8 12.9 25.2 1.3 12.4 2.6 SMIM12 "C1orf212, FLJ90372" ENSG00000163866 "Small integral membrane protein 12" Q96EX1 1 34712737-34859755 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065331 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA065331: AB_2685470" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.64e-1)" "unprognostic (2.05e-1)" "unprognostic (5.71e-2)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "prognostic favorable (1.15e-5)" "unprognostic (7.33e-2)" "unprognostic (6.70e-2)" "unprognostic (3.58e-2)" "unprognostic (2.52e-2)" 40.2 56.6 31.7 26.5 32.1 24.8 33.5 29.5 35.3 20.9 29.2 34.0 30.1 26.0 17.7 41.3 23.5 17.3 53.8 31.5 35.7 42.3 87.9 31.6 25.0 32.6 32.7 17.1 26.4 31.8 26.9 24.8 33.1 19.9 28.0 12.8 24.1 20.5 56.2 29.7 30.8 31.5 29.6 31.9 30.4 28.0 31.9 30.3 24.9 51.1 27.3 29.2 25.7 33.3 52.9 39.8 43.3 31.6 55.2 43.3 30.1 55.8 48.1 70.2 60.3 40.0 65.0 55.1 49.2 57.6 55.5 51.7 55.5 74.7 53.5 67.3 41.6 98.1 65.6 49.1 51.3 107.9 55.4 66.2 71.9 76.5 61.3 25.3 72.9 47.0 71.0 72.3 63.0 38.6 52.6 55.4 70.1 40.8 52.7 44.1 42.7 71.7 62.2 54.6 41.5 32.9 52.0 48.1 81.5 53.9 32.8 29.9 69.9 47.8 49.3 74.3 66.7 40.4 60.2 56.9 45.2 63.7 32.1 104.2 76.0 126.4 65.8 82.0 77.9 57.7 60.4 72.0 86.0 59.2 50.1 64.3 50.2 62.6 67.5 62.4 76.2 87.5 31.7 32.1 29.5 35.3 31.5 35.7 32.6 32.7 33.1 29.6 31.9 33.3 51.2 25.6 13.1 4.9 37.0 68.2 26.3 49.8 23.3 14.4 36.4 30.1 33.9 42.9 30.4 22.0 10.4 50.7 38.5 46.7 86.1 78.7 58.3 17.1 19.0 56.2 21.8 53.9 10.4 83.7 60.2 24.9 20.9 20.6 23.5 18.9 48.2 89.3 83.8 20.2 9.5 23.4 46.8 41.7 61.6 32.7 14.9 41.0 39.2 7.5 89.8 24.9 54.6 6.6 7.0 87.5 41.0 23.3 27.5 40.8 62.9 90.6 26.8 17.3 13.1 21.8 52.3 37.6 23.0 41.4 75.6 58.0 40.8 33.7 39.6 41.7 SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.6;pancreas: 154.3;salivary gland: 147.2;stomach 1: 201.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2005.0;Intestinal goblet cells: 1223.5;Paneth cells: 1462.9;Proximal enterocytes: 1685.8;Respiratory ciliated cells: 686.7;Undifferentiated cells: 775.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 261.7;OE19: 247.3;RT4: 89.8;SCLC-21H: 70.7;SK-BR-3: 201.2" "Low region specificity" "Detected in many" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA077331: AB_2686834" "unprognostic (6.55e-2)" "unprognostic (4.12e-2)" "unprognostic (4.84e-2)" "unprognostic (3.69e-3)" "unprognostic (7.82e-2)" "unprognostic (3.84e-2)" "unprognostic (4.63e-2)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (3.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (1.73e-3)" 1.2 0.3 0.1 14.6 1.2 3.5 48.2 4.6 2.0 45.4 0.0 193.6 129.6 8.9 50.4 10.3 77.3 33.3 0.5 0.5 0.4 42.0 1.4 24.1 0.6 2.6 0.9 0.5 154.3 0.1 48.9 2.0 2.1 42.6 122.7 1.5 147.2 36.3 0.2 10.4 128.4 6.3 0.8 0.2 201.7 33.8 2.6 0.2 1.1 0.0 2.7 46.1 6.5 3.1 0.2 0.0 0.1 0.6 0.0 0.0 1.9 0.3 0.1 0.1 0.1 0.6 261.7 0.3 7.3 0.0 0.3 1.3 0.1 0.0 0.1 0.4 1.9 0.1 5.8 0.9 0.1 0.7 0.3 0.2 1.4 0.0 0.0 0.2 0.1 0.4 0.0 0.6 0.0 1.9 0.1 0.6 0.8 247.3 0.0 0.8 0.3 23.6 1.5 89.8 70.7 0.8 0.5 201.2 0.0 0.5 15.2 0.0 0.0 0.6 0.8 1.1 0.1 0.2 0.6 0.9 0.0 0.7 0.6 1.2 0.3 0.4 0.3 0.1 0.1 0.1 0.3 0.1 0.0 0.4 0.3 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.1 1.2 4.6 2.0 0.5 0.4 2.6 0.9 2.1 0.8 2.6 3.1 1.4 48.1 117.7 0.0 5.8 2.2 22.7 92.7 0.0 4.2 363.3 267.5 0.5 183.0 154.9 250.1 0.0 3.9 3.0 2005.0 25.4 259.8 40.1 430.4 26.5 4.4 470.3 0.0 0.5 381.9 0.4 4.7 438.8 258.3 18.4 0.1 0.4 0.2 0.4 1.7 0.3 1223.5 152.5 0.0 0.8 107.3 0.6 4.2 23.2 0.0 5.3 0.6 0.0 0.0 1.3 539.9 1462.9 1.2 1.0 29.5 1685.8 99.4 686.7 4.2 0.0 0.0 15.9 38.6 0.6 2.3 2.3 3.7 6.6 0.2 775.6 148.6 SMIM3 "C5orf62, MSTP150, NID67" ENSG00000256235 "Small integral membrane protein 3" Q9BZL3 5 150778757-150796734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 161.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.5;Basal squamous epithelial cells: 80.8;granulocytes: 90.0;Macrophages: 79.3;Sertoli cells: 138.1;Smooth muscle cells: 77.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 409.9;ASC TERT1: 200.1;LHCN-M2: 193.8;U-87 MG: 291.5" "Low region specificity" "Detected in all" HPA075345 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA075345: AB_2686744" "unprognostic (2.33e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "unprognostic (9.45e-2)" "unprognostic (5.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.47e-1)" "unprognostic (3.90e-1)" "unprognostic (2.05e-2)" "unprognostic (9.71e-3)" "unprognostic (3.46e-3)" "prognostic unfavorable (1.15e-8)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.46e-3)" 161.0 36.2 20.5 25.5 20.3 89.5 71.5 20.9 26.4 21.9 42.1 26.8 13.4 16.2 22.6 16.8 30.2 25.7 36.8 20.5 22.1 34.9 12.2 30.9 11.7 23.3 21.5 25.9 33.7 26.9 15.1 46.0 23.6 27.6 19.1 20.4 14.0 24.1 15.0 12.5 23.0 28.3 20.7 25.2 21.6 4.1 23.5 17.7 21.0 15.5 8.8 29.0 18.7 19.6 13.8 4.5 7.3 60.8 409.9 200.1 15.9 52.3 114.6 19.2 77.2 21.5 35.3 0.0 3.1 55.1 12.7 10.7 12.5 11.8 28.6 0.2 3.8 20.0 2.8 9.9 72.4 19.7 130.0 167.9 23.6 54.2 25.1 122.3 6.4 46.6 5.5 0.4 193.8 10.5 28.5 27.0 3.8 10.7 12.5 15.2 1.2 0.0 20.6 10.2 1.8 4.7 7.8 1.1 16.1 8.1 25.4 120.6 10.1 84.2 15.2 65.9 27.5 0.0 0.4 0.2 291.5 75.0 10.8 68.7 41.0 72.4 20.8 17.2 12.7 1.3 14.5 14.4 19.4 0.2 14.1 12.1 42.7 13.0 16.2 57.3 2.3 38.0 20.5 20.3 20.9 26.4 20.5 22.1 23.3 21.5 23.6 20.7 23.5 19.6 53.7 6.4 8.6 2.6 3.2 0.0 85.5 0.0 80.8 0.8 12.0 16.6 9.9 7.2 2.5 7.3 0.0 8.5 22.8 4.0 13.7 6.4 0.8 1.3 11.1 25.4 4.8 8.4 1.0 31.3 5.0 53.5 2.6 1.1 90.0 1.7 13.2 1.0 45.2 0.0 2.0 36.8 0.0 34.2 0.0 0.6 14.0 79.3 0.0 16.9 30.2 62.1 11.3 5.5 0.1 18.2 1.1 36.9 3.5 15.9 3.9 8.8 0.0 1.9 138.1 72.3 77.2 0.1 0.5 20.1 0.0 8.1 28.8 3.0 7.4 40.1 SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 887.2;urinary bladder: 450.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 283.5;Hepatic stellate cells: 121.3;Sertoli cells: 184.1;Smooth muscle cells: 116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 140000 "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: AB_2681607, HPA058590: AB_2683765" "unprognostic (1.36e-2)" "unprognostic (4.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (1.08e-3)" "unprognostic (2.05e-2)" "unprognostic (4.56e-1)" "unprognostic (2.15e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (8.41e-3)" "unprognostic (6.34e-2)" 54.7 19.2 10.8 25.3 12.5 4.7 42.2 10.3 13.1 100.2 7.6 887.2 30.0 251.0 7.0 65.1 132.4 20.8 152.0 9.0 9.3 35.6 15.3 38.2 5.6 11.7 12.5 34.0 25.2 3.3 9.8 17.4 11.0 150.9 29.2 15.2 16.3 177.9 95.7 38.7 151.5 127.2 10.5 54.5 231.2 12.5 12.4 2.9 26.4 26.2 2.5 450.6 91.5 10.0 73.0 21.2 7.2 27.0 11.0 17.2 58.0 106.8 49.1 85.7 58.4 29.9 22.4 32.1 9.3 59.3 17.3 10.6 7.2 62.8 40.4 10.6 58.2 33.9 18.3 36.1 9.7 51.5 57.4 14.2 5.8 114.0 18.7 29.2 74.7 12.3 37.3 25.9 59.6 64.5 5.9 11.4 8.2 36.1 90.0 20.3 20.5 34.6 34.5 23.2 11.5 12.7 33.4 15.9 15.7 7.4 18.8 8.2 118.7 62.1 58.4 59.4 79.8 24.6 32.5 18.8 91.0 19.7 200.5 0.0 1.0 0.0 0.1 0.2 0.0 1.3 0.1 0.3 0.4 0.0 1.0 0.5 0.1 0.1 0.2 0.2 0.0 0.6 10.8 12.5 10.3 13.1 9.0 9.3 11.7 12.5 11.0 10.5 12.4 10.0 94.5 6.4 3.3 23.8 2.0 65.1 33.5 16.1 19.4 46.6 18.6 26.7 39.5 5.7 6.1 9.2 283.5 13.4 2.7 12.8 9.8 14.8 1.2 4.0 52.1 62.8 29.2 0.0 0.2 20.1 68.8 35.9 18.3 7.3 0.0 11.0 121.3 2.6 6.0 5.0 1.9 29.9 14.2 6.8 14.6 1.9 22.4 4.7 14.2 7.5 1.0 31.2 1.0 4.5 2.0 73.2 11.4 48.5 2.1 21.7 5.6 18.4 2.2 54.0 184.1 18.4 116.4 5.7 7.9 9.7 69.3 21.9 3.7 16.3 27.0 14.9 SNAI3 "SMUC, Zfp293, ZNF293" ENSG00000185669 "Snail family transcriptional repressor 3" Q3KNW1 16 88677688-88686507 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 31.3" "Cell type enhanced" "Detected in some" "dendritic cells: 19.7;granulocytes: 9.5;Kupffer cells: 14.6;Langerhans cells: 9.3;Macrophages: 9.4;NK-cells: 17.5;Plasma cells: 14.0;T-cells: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "NB-4: 18.2;RPMI-8226: 28.6" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Not detected" "Not detected" HPA071127 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA071127: AB_2686346" "unprognostic (1.03e-2)" "prognostic favorable (1.39e-4)" "unprognostic (2.20e-2)" "unprognostic (6.19e-4)" "unprognostic (3.05e-1)" "unprognostic (2.85e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (3.24e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.58e-4)" "unprognostic (9.09e-2)" "unprognostic (1.62e-1)" "unprognostic (8.46e-2)" "unprognostic (6.57e-2)" "unprognostic (1.11e-1)" "unprognostic (7.47e-2)" 0.7 0.5 1.5 2.4 2.4 1.8 0.4 0.0 3.3 0.6 0.0 1.2 1.5 0.6 0.3 0.6 0.8 1.0 2.4 1.9 0.0 0.7 0.8 2.2 3.9 2.1 0.0 0.5 1.7 1.5 0.7 0.1 3.7 0.8 0.3 0.3 1.2 0.2 31.3 0.6 3.7 0.2 0.0 6.9 3.3 0.9 0.0 0.8 0.9 7.3 2.6 1.4 0.5 0.0 0.3 0.9 0.3 1.3 0.0 0.0 0.6 0.3 0.0 0.0 0.1 3.5 0.3 2.3 0.5 0.0 0.8 0.8 0.3 0.2 0.0 0.4 1.2 1.1 0.1 1.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.5 2.1 4.3 0.0 3.2 0.2 18.2 0.4 0.3 0.4 3.9 0.3 28.6 0.0 0.4 1.7 0.2 0.7 0.0 0.2 0.4 1.2 2.2 0.3 0.1 1.0 0.2 0.0 0.7 4.2 4.0 0.3 4.9 0.5 5.2 14.1 48.5 10.2 5.3 18.8 7.8 16.7 9.8 16.7 6.1 10.0 6.4 30.9 1.1 1.5 11.9 21.4 10.9 1.5 2.4 0.0 3.3 1.9 0.0 2.1 0.0 3.7 0.0 0.0 0.0 0.3 3.2 0.0 2.0 8.5 0.5 0.1 0.4 0.0 0.2 0.4 0.5 2.0 0.0 0.7 0.0 0.0 0.0 19.7 0.0 1.9 0.1 0.0 0.6 0.0 0.4 0.0 0.4 6.4 0.4 0.5 0.2 0.5 0.1 9.5 0.0 0.4 0.1 6.9 0.0 3.7 0.1 2.0 14.6 9.3 0.3 0.0 9.4 5.4 0.0 5.3 0.1 17.5 1.0 1.9 0.1 1.1 0.4 14.0 0.1 0.0 0.2 1.0 0.9 0.0 0.7 0.4 0.0 1.5 0.2 0.3 0.1 14.0 0.0 0.3 0.1 SNN ENSG00000184602 Stannin O75324 16 11668455-11679152 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 126.0;skeletal muscle: 114.9" "Cell type enhanced" "Detected in many" "Langerhans cells: 108.2;Macrophages: 64.7;Muller glia cells: 146.9" "Cancer enhanced" "Detected in all" "glioma: 62.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AF22: 74.9;REH: 73.1" "Low region specificity" "Detected in all" HPA011055 Approved Uncertain Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA011055: AB_1857326" "unprognostic (1.94e-1)" "unprognostic (7.26e-2)" "unprognostic (2.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (4.51e-2)" "unprognostic (3.45e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-2)" "unprognostic (2.14e-1)" "prognostic favorable (1.83e-5)" "unprognostic (4.91e-2)" "unprognostic (2.09e-1)" "unprognostic (3.58e-1)" "unprognostic (4.72e-2)" 57.4 29.4 114.1 19.8 126.0 24.5 24.3 91.6 101.7 18.3 49.4 16.9 9.1 14.0 20.2 19.1 12.8 22.0 28.4 117.4 87.9 14.5 9.3 21.6 30.8 92.8 102.9 17.0 8.7 9.9 15.4 8.2 83.6 14.3 5.7 40.5 18.3 21.9 114.9 14.8 14.4 10.5 93.3 34.6 14.1 3.9 108.9 28.6 17.3 36.9 27.5 18.5 14.6 89.0 7.6 7.2 74.9 20.5 48.7 13.8 7.2 3.2 6.8 9.0 9.1 11.7 5.2 7.8 30.6 10.6 15.9 14.6 22.7 9.1 6.9 2.1 5.1 25.8 8.1 15.3 12.9 1.8 14.9 12.1 40.7 4.8 10.0 12.7 16.8 22.4 4.1 12.0 8.4 12.7 21.0 5.8 39.0 9.5 5.2 73.1 10.0 53.8 8.5 21.9 44.4 18.0 17.4 22.6 11.5 29.1 9.1 15.2 15.1 10.4 21.3 61.2 3.3 4.8 3.3 18.1 6.2 22.0 13.4 0.1 21.0 16.0 0.6 36.2 0.6 15.2 3.3 1.5 19.9 15.5 6.1 4.5 53.0 0.7 48.6 8.0 2.2 17.1 114.1 126.0 91.6 101.7 117.4 87.9 92.8 102.9 83.6 93.3 108.9 89.0 27.5 0.0 6.1 11.8 46.8 18.4 19.9 9.5 18.8 7.5 7.3 10.0 16.6 14.3 6.9 5.5 0.0 1.3 16.8 0.4 25.4 16.7 0.7 6.8 7.8 17.9 5.3 0.0 28.6 18.3 23.1 9.4 3.1 8.4 13.4 5.7 27.1 3.0 20.7 6.7 11.6 0.5 14.2 39.5 108.2 0.5 5.0 64.7 21.4 11.2 58.2 146.9 4.1 8.5 5.0 14.6 0.3 15.4 2.9 14.6 0.9 5.2 6.7 6.5 6.6 17.7 16.9 0.4 3.8 15.3 19.0 1.4 12.1 1.1 0.4 13.2 SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 55.0;breast: 14.2;skin 1: 32.2" "Group enriched" "Detected in some" 22 "Breast glandular cells: 367.0;Breast myoepithelial cells: 324.9" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "basophil: 2.8" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.8" "Cell line enriched" "Detected in some" 13 "Hep G2: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" 1.3 0.9 6.7 0.2 14.1 0.5 14.2 21.2 8.5 0.7 0.2 3.3 0.9 0.7 0.5 1.0 1.2 0.0 0.8 11.9 23.5 1.3 7.4 0.8 0.6 37.8 14.8 0.7 1.7 0.3 1.6 0.2 28.3 1.5 0.3 0.6 4.7 0.1 1.0 32.2 1.7 0.1 38.2 1.1 0.8 8.1 14.2 0.1 0.6 0.0 0.0 0.9 0.8 55.0 0.9 0.0 0.3 1.4 1.0 1.6 2.4 0.3 0.0 0.3 0.7 0.0 0.2 0.0 0.7 0.1 0.5 0.5 0.0 0.0 0.0 0.6 2.1 0.5 0.4 59.6 0.8 0.1 1.7 0.0 1.3 0.4 0.8 0.7 1.6 0.6 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.0 2.2 0.4 0.6 0.4 0.1 0.9 0.2 0.8 0.4 0.0 2.2 1.0 0.1 2.6 0.9 0.2 0.8 0.8 0.8 3.8 4.7 0.2 0.1 1.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 14.1 21.2 8.5 11.9 23.5 37.8 14.8 28.3 38.2 14.2 55.0 3.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 367.0 324.9 0.0 0.0 0.0 1.8 0.0 0.1 10.1 0.0 5.9 0.5 0.0 3.8 0.4 6.3 0.0 0.0 0.0 0.8 0.1 2.9 0.0 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 2.3 0.9 0.0 0.0 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SNTA1 "LQT12, SNT1, TACIP1" ENSG00000101400 "Syntrophin alpha 1" Q13424 20 33407957-33443763 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 198.3;skeletal muscle: 307.9;tongue: 327.9" "Cell type enhanced" "Detected in many" "Astrocytes: 117.2;Cardiomyocytes: 175.1;Muller glia cells: 83.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 10.4" "Group enriched" "Detected in many" 4 "B-cells: 5.7;dendritic cells: 10.4" "Cell line enhanced" "Detected in many" "ASC diff: 66.5" "Low region specificity" "Detected in all" "CAB037059, HPA067154" Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB037059: AB_261497, HPA067154: " "unprognostic (2.25e-2)" "unprognostic (1.29e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (9.60e-6)" "unprognostic (5.68e-2)" "unprognostic (6.48e-2)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "prognostic favorable (7.08e-4)" "unprognostic (2.16e-1)" "prognostic favorable (3.72e-4)" "unprognostic (1.99e-1)" "unprognostic (8.09e-2)" "unprognostic (5.16e-2)" "unprognostic (1.48e-2)" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" 39.2 18.7 162.7 4.5 179.8 2.0 25.5 158.2 198.3 24.9 127.9 23.7 6.6 16.9 8.0 22.6 20.4 7.6 195.9 158.1 149.3 23.0 16.6 8.0 5.9 167.9 166.0 20.6 13.5 20.9 12.4 3.1 144.5 19.6 3.0 15.0 31.3 18.1 307.9 15.0 13.7 9.3 147.4 5.0 23.8 19.3 178.7 3.4 77.8 327.9 5.2 38.6 17.0 144.5 13.0 6.5 2.9 28.2 66.5 13.0 2.8 9.8 13.6 18.3 15.2 16.9 4.3 9.3 11.6 16.8 33.4 16.9 8.4 5.4 3.2 1.9 10.8 0.5 15.7 23.9 18.8 0.9 1.6 12.0 6.7 8.0 3.0 10.1 2.8 8.8 22.8 3.5 9.3 1.6 17.7 2.2 1.6 1.9 37.2 11.1 20.8 10.3 3.8 11.6 12.3 10.6 38.5 11.5 19.4 2.2 17.8 1.6 4.6 9.0 17.5 36.1 9.2 21.2 11.7 5.6 19.5 1.7 1.4 0.0 0.0 0.0 0.9 0.0 1.9 5.7 0.9 0.9 0.0 2.8 0.3 0.7 0.0 0.0 0.0 10.4 1.1 0.3 162.7 179.8 158.2 198.3 158.1 149.3 167.9 166.0 144.5 147.4 178.7 144.5 4.6 3.2 2.0 117.2 5.1 3.2 4.7 1.3 1.2 5.7 6.2 8.0 175.1 8.6 1.9 1.8 4.2 1.2 4.9 1.3 39.2 2.0 1.0 1.2 3.7 4.4 4.2 5.7 12.7 2.6 1.9 13.4 5.1 4.1 0.0 10.1 3.9 9.1 1.9 0.0 8.3 1.6 8.2 1.9 2.3 2.3 25.1 1.6 5.4 10.3 0.0 83.7 3.1 5.0 6.3 3.3 1.6 28.2 2.3 5.7 5.4 33.5 0.8 36.5 26.3 12.7 36.7 1.8 4.9 3.5 2.8 0.8 9.3 3.2 1.6 5.6 SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.4;Muller glia cells: 214.1;Rod photoreceptor cells: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" 11.0 5.0 3.3 5.2 3.9 2.7 8.8 1.0 6.7 11.0 10.1 6.7 3.7 10.4 5.1 7.0 8.7 7.1 5.3 4.6 0.8 6.7 3.8 8.6 5.6 2.5 0.9 6.2 4.1 12.4 4.0 5.2 0.9 8.2 5.3 21.6 5.2 5.5 5.7 8.5 6.0 8.7 0.6 5.7 6.1 7.1 1.5 5.8 10.5 3.8 4.9 8.7 8.7 3.7 7.2 10.9 7.4 5.8 26.6 35.6 9.1 13.9 19.3 10.7 11.8 10.7 6.5 9.0 8.3 16.2 5.6 12.9 10.0 6.8 13.9 4.0 5.5 4.0 11.1 9.2 8.8 0.3 5.9 25.6 4.9 17.6 7.1 11.1 32.4 2.5 2.3 13.8 13.1 8.2 3.0 1.4 5.0 4.2 8.6 18.1 6.5 16.8 5.7 10.9 2.8 6.1 42.6 6.0 4.4 5.5 7.1 0.5 25.4 20.0 9.6 14.2 13.0 3.1 5.2 10.0 12.8 1.4 9.3 0.4 0.2 0.3 0.9 0.3 0.9 0.2 0.4 0.5 0.2 0.2 0.2 1.1 0.9 0.7 0.3 0.1 0.5 0.3 3.3 3.9 1.0 6.7 4.6 0.8 2.5 0.9 0.9 0.6 1.5 3.7 55.9 19.2 11.7 36.6 9.0 38.0 28.0 17.1 70.0 33.2 19.0 25.0 9.2 10.0 10.4 27.6 41.7 9.5 33.7 29.0 3.9 9.7 25.9 20.6 61.3 81.4 10.3 4.8 151.4 24.1 7.9 53.1 20.9 28.7 1.3 15.8 126.7 11.1 6.9 5.0 62.6 16.6 8.2 33.1 29.3 27.5 59.0 12.9 30.2 33.7 8.6 214.1 47.4 30.7 27.9 16.3 32.8 65.1 20.7 40.9 12.7 34.5 10.0 136.7 6.6 26.0 35.6 27.9 15.4 30.7 38.8 3.7 32.8 20.2 19.6 28.7 SNX10 ENSG00000086300 "Sorting nexin 10" Q9Y5X0 7 26291862-26374383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 285.7;Hofbauer cells: 148.7;Kupffer cells: 215.5;Macrophages: 166.5;monocytes: 152.3;Muller glia cells: 310.5;Proximal tubular cells: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 336.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 103.1;U-937: 87.3;WM-115: 297.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015605, HPA064782" Approved Supported Nucleoplasm,Nucleoli,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Microtubules" Nucleoli "HPA015605: AB_1857342, HPA064782: AB_2685349" "unprognostic (6.42e-2)" "unprognostic (2.72e-3)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.92e-2)" "unprognostic (2.48e-3)" "unprognostic (4.51e-2)" "unprognostic (4.87e-1)" "unprognostic (9.36e-2)" "unprognostic (1.59e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (8.06e-5)" "unprognostic (1.12e-2)" "unprognostic (3.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.50e-1)" 23.7 14.5 26.4 34.7 27.8 42.1 11.0 17.6 45.9 4.5 6.1 5.6 4.1 9.0 1.1 2.9 3.0 8.8 1.8 30.2 42.2 37.8 69.1 41.2 36.9 29.1 28.2 1.1 7.8 1.3 4.7 10.9 40.3 3.5 6.4 47.1 1.7 2.1 1.0 1.4 6.2 9.5 18.6 42.1 3.9 5.1 32.0 15.8 2.9 2.7 24.8 10.9 1.6 26.8 55.8 5.0 0.2 10.1 0.1 0.0 57.8 0.0 3.9 0.1 0.0 0.5 18.4 24.0 41.4 0.0 36.2 1.7 13.5 3.6 0.0 33.3 12.4 2.5 0.4 36.3 0.1 52.2 8.9 0.6 5.4 0.0 4.2 0.1 0.8 30.7 1.5 0.3 0.0 9.7 22.2 54.3 15.3 0.9 5.1 0.1 0.1 1.3 103.1 12.0 22.5 7.1 11.7 8.5 62.7 18.1 15.2 72.6 0.3 0.1 12.2 0.2 13.7 17.9 15.5 16.4 0.5 87.3 297.4 55.9 144.7 3.7 18.6 158.5 18.2 82.3 13.2 16.4 101.2 71.7 6.9 12.0 336.7 47.7 162.5 37.0 29.6 70.0 26.4 27.8 17.6 45.9 30.2 42.2 29.1 28.2 40.3 18.6 32.0 26.8 3.3 3.2 14.7 6.8 63.4 5.4 1.2 0.7 1.8 20.3 17.6 9.5 1.8 34.3 4.4 23.9 2.1 14.9 18.6 2.5 285.7 66.0 1.3 2.1 40.7 7.6 9.5 19.1 63.1 27.1 111.8 3.4 0.0 2.3 31.1 2.9 2.2 109.8 148.7 35.3 53.4 3.3 0.0 215.5 130.3 2.1 1.2 166.5 8.8 19.7 152.3 310.5 33.0 7.1 8.5 14.1 1.5 0.0 8.0 4.4 4.5 204.9 0.8 23.2 0.0 0.7 4.7 7.1 29.5 0.8 3.0 28.7 31.6 0.9 8.7 1.3 SNX2 ENSG00000205302 "Sorting nexin 2" O60749 5 122775079-122834543 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 290.2;naive B-cell: 289.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037400 Approved Supported Endosomes,Lysosomes NA NA 150000 "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" "HPA037400: AB_10670381" "unprognostic (9.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" "unprognostic (3.27e-2)" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "prognostic favorable (8.76e-7)" "unprognostic (8.76e-2)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" 40.6 31.0 6.0 17.9 6.5 14.2 33.8 9.5 8.5 27.8 6.2 32.6 13.4 28.2 12.5 30.1 29.0 12.8 22.4 6.2 6.5 37.8 28.0 33.7 26.5 6.4 7.0 37.1 31.3 14.1 23.2 19.2 6.5 24.2 14.5 7.1 29.1 10.1 27.0 29.0 34.8 17.9 6.9 52.4 32.9 17.1 7.1 10.4 38.3 7.7 24.0 33.6 26.1 8.5 18.9 14.1 18.7 13.1 27.8 19.0 79.6 6.2 21.1 15.1 24.2 27.1 27.2 18.8 18.5 14.9 37.4 6.1 24.6 16.2 18.0 13.4 12.2 23.3 15.8 29.7 19.7 7.7 10.8 16.1 12.8 9.6 16.6 17.6 16.8 15.4 10.1 14.9 14.0 16.1 5.5 11.6 6.3 22.2 10.7 20.2 14.3 25.4 17.3 33.9 12.0 13.3 16.0 19.8 17.0 46.4 24.2 16.0 10.7 13.7 6.9 19.1 11.7 4.4 14.9 24.4 13.6 32.1 15.6 77.9 78.5 57.0 15.4 89.1 18.3 290.2 25.7 24.2 66.5 289.1 23.6 21.0 34.7 18.5 86.6 20.1 48.7 72.7 6.0 6.5 9.5 8.5 6.2 6.5 6.4 7.0 6.5 6.9 7.1 8.5 48.4 35.3 42.8 33.0 260.8 40.7 46.9 82.3 45.5 43.1 23.8 29.3 34.4 40.0 62.4 80.9 8.4 153.9 36.2 19.9 131.0 69.1 25.5 71.5 44.7 49.0 31.8 34.3 38.5 51.8 244.9 62.1 52.5 52.2 65.1 41.8 89.6 31.4 349.2 26.9 42.2 32.6 69.2 125.8 75.8 15.0 53.4 133.0 33.8 61.8 215.8 71.7 23.7 51.8 51.4 35.7 37.0 53.0 37.5 28.1 57.8 114.7 77.8 38.0 46.0 42.8 74.5 89.1 75.9 32.9 38.9 122.9 47.2 92.4 39.8 37.5 SNX21 "C20orf161, dJ337O18.4, SNX-L" ENSG00000124104 "Sorting nexin family member 21" Q969T3 20 45833799-45843276 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Theca cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.8;classical monocyte: 1.6;eosinophil: 4.8;intermediate monocyte: 2.6;non-classical monocyte: 2.0" "Group enriched" "Detected in many" 8 "granulocytes: 4.8;monocytes: 2.6" "Cell line enhanced" "Detected in many" "EFO-21: 17.9;PC-3: 29.8;U-87 MG: 18.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046359 Approved Approved "Vesicles,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Centriolar satellite" "HPA046359: AB_10963216" "unprognostic (1.97e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (4.16e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (4.96e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-2)" "unprognostic (2.18e-1)" 25.0 27.8 4.9 1.1 4.1 0.7 18.7 5.8 7.9 26.4 4.9 15.8 3.7 28.6 0.8 14.1 24.6 5.0 14.9 3.5 2.8 11.9 6.2 10.9 1.3 9.2 5.1 30.5 4.2 3.3 10.9 2.9 6.5 14.4 1.2 0.7 9.7 4.8 31.9 47.9 7.5 1.9 3.0 7.3 11.3 6.1 7.2 0.5 9.1 6.7 0.6 25.7 19.5 4.6 4.3 6.7 1.0 6.5 7.8 7.5 4.3 6.8 5.0 5.0 4.0 5.0 3.0 0.1 17.9 4.8 4.1 5.5 0.2 4.5 0.8 0.3 1.4 0.1 4.1 4.6 3.3 0.0 1.3 3.9 2.7 4.8 0.4 1.7 3.6 1.1 0.1 0.0 0.9 11.1 0.1 0.8 1.8 0.8 29.8 0.1 0.5 0.2 1.0 0.7 1.2 11.6 14.6 10.3 8.1 0.8 5.9 1.2 6.4 6.0 7.2 17.2 5.5 0.2 0.9 0.2 18.1 0.0 4.4 2.8 1.6 4.8 0.0 2.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 2.0 0.1 0.4 0.3 4.9 4.1 5.8 7.9 3.5 2.8 9.2 5.1 6.5 3.0 7.2 4.6 11.1 9.6 8.3 25.1 1.0 10.1 4.7 6.4 8.6 18.4 8.6 8.5 4.8 7.2 10.3 5.5 8.4 4.9 0.4 10.3 25.4 10.3 3.7 5.0 27.0 10.3 9.0 0.0 4.8 11.7 5.2 37.0 6.6 7.5 0.0 27.0 10.4 4.3 4.8 15.2 5.7 9.2 4.1 7.1 10.0 18.3 19.6 5.4 10.6 3.7 3.3 14.8 1.0 8.5 6.5 8.4 5.9 17.0 0.8 3.7 15.9 15.7 6.6 15.6 6.6 16.4 20.1 0.9 2.4 4.1 22.7 2.5 2.2 62.2 7.0 3.4 SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 800.2;Cardiomyocytes: 612.3;Excitatory neurons: 401.1;Inhibitory neurons: 295.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.1" "Cell line enhanced" "Detected in many" "CACO-2: 28.0;Hep G2: 19.5;HMC-1: 48.3;SK-MEL-30: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, CAB032850, HPA043084" Enhanced Supported "Plasma membrane,Focal adhesion sites,Centrosome" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "Plasma membrane, Centrosome" "CAB032850: AB_2286335, HPA027559: AB_10600812, HPA043084: AB_2678307" "prognostic favorable (2.84e-4)" "unprognostic (3.53e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.41e-1)" "unprognostic (2.98e-2)" "unprognostic (5.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-2)" "unprognostic (5.01e-3)" 370.8 21.6 128.5 53.3 153.3 4.7 78.3 101.7 144.1 46.0 42.6 312.8 25.6 169.4 32.1 155.5 99.2 81.3 351.6 127.0 165.4 17.6 49.3 34.4 3.1 164.0 161.5 19.0 22.0 26.4 11.5 30.3 126.7 140.6 67.0 39.0 24.5 217.4 190.5 24.5 62.7 151.0 138.9 8.1 143.1 14.4 127.0 3.7 14.8 155.9 1.5 235.3 47.1 139.9 1.6 1.2 12.4 3.1 4.2 0.2 2.4 0.4 0.1 0.4 0.1 28.0 10.9 0.0 2.2 0.2 4.2 0.6 2.4 0.6 0.4 3.2 4.5 7.2 0.4 19.5 1.5 0.0 48.3 0.9 0.4 0.5 0.3 0.2 4.9 1.9 11.7 2.3 1.3 0.8 0.1 0.8 5.7 6.2 2.6 1.0 4.0 0.4 15.1 18.3 4.9 3.7 1.8 0.6 45.2 8.9 2.1 0.4 0.3 0.1 4.0 0.1 2.4 1.8 0.5 0.2 4.8 0.5 11.7 6.1 0.1 1.2 0.4 0.6 0.5 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 128.5 153.3 101.7 144.1 127.0 165.4 164.0 161.5 126.7 138.9 127.0 139.9 42.2 22.4 20.9 800.2 0.8 11.6 8.7 0.0 5.2 7.5 6.5 19.3 612.3 12.8 1.3 1.8 2.1 20.2 1.0 4.0 3.9 7.2 70.4 1.4 15.8 25.7 6.0 16.0 401.1 3.1 2.4 21.4 8.6 1.6 16.4 8.2 30.4 50.5 3.1 6.7 295.1 10.9 0.0 3.8 12.0 48.6 7.5 1.1 14.2 163.9 0.7 22.1 1.0 155.3 22.6 2.3 2.8 76.8 1.1 4.7 1.2 6.1 0.1 5.5 0.0 11.8 51.6 3.4 3.7 1.9 12.5 29.6 1.6 0.1 5.1 5.9 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 2.0 15.7 4.9 3.1 3.8 2.8 53.8 7.4 8.4 163.8 1.9 5.3 7.5 4.3 6.9 10.2 6.7 8.2 5.6 5.0 4.5 50.3 247.0 3.2 2.6 4.3 3.7 2.4 5.7 4.4 3.1 2.5 4.0 87.9 7.8 4.8 5.3 27.0 2.2 16.6 7.2 3.5 4.2 2.3 9.2 12.2 3.9 3.7 89.4 2.8 3.4 9.1 6.9 6.3 12.3 12.2 4.7 20.8 4.4 5.3 5.9 1.8 3.5 12.2 7.0 12.2 5.8 2.7 8.0 5.4 4.1 17.6 19.9 19.1 9.2 29.9 12.3 13.5 12.1 50.3 0.2 18.0 25.5 6.7 18.0 6.6 9.5 5.4 12.5 15.1 11.7 10.6 14.9 8.1 18.4 38.3 39.0 29.4 13.8 0.9 16.6 6.4 16.8 12.1 25.1 12.2 2.1 57.3 5.9 5.2 16.4 22.5 4.7 3.5 38.0 1.6 5.8 8.7 4.5 4.4 14.2 18.6 10.6 86.3 1.7 55.9 1.6 1.5 1.7 5.4 1.3 1.6 1.7 6.9 1.6 1.4 3.8 1.1 2.1 2.4 2.5 2.0 4.9 3.8 7.4 8.4 5.0 4.5 4.3 3.7 4.0 4.2 3.9 6.3 3.9 0.0 3.1 5.5 11.9 7.8 26.5 14.8 17.6 10.8 24.7 17.5 3.2 25.8 28.1 33.1 0.0 1.3 2.3 15.0 29.4 68.2 31.7 40.2 17.4 4.9 84.8 37.5 4.8 138.7 5.1 7.5 31.1 43.7 8.8 11.5 15.7 649.4 16.0 3.3 5.4 32.5 22.4 24.2 6.4 24.1 3.7 12.2 16.0 1.0 13.3 9.0 2.1 7.1 8.9 89.0 18.1 6.0 7.9 218.8 8.0 270.2 42.5 4.7 0.0 8.9 8.9 7.4 2.8 35.1 20.3 1.0 6.5 15.3 39.4 131.2 SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" 48.2 11.3 71.0 12.0 168.3 21.4 25.1 124.3 114.2 17.7 21.5 29.5 22.1 24.7 139.8 41.5 27.5 17.8 64.7 131.8 90.0 38.7 6.5 37.4 2.8 151.9 133.8 6.1 17.5 46.5 11.3 44.8 153.1 18.3 26.9 40.0 25.2 44.0 85.0 19.0 21.9 27.8 102.8 10.2 18.2 43.5 118.0 6.4 42.7 71.8 10.3 16.9 18.0 285.6 38.8 15.3 37.5 45.8 107.0 21.2 107.3 28.2 44.9 27.2 29.0 39.8 14.0 0.3 35.2 11.9 19.9 9.4 44.7 22.3 38.9 1.1 21.2 10.7 23.5 43.1 41.8 0.2 33.5 53.2 3.6 33.3 7.3 72.6 4.2 31.7 81.3 4.0 38.7 41.1 27.9 0.8 14.1 17.5 6.3 30.7 87.9 18.9 52.0 27.8 38.3 21.8 16.6 109.3 120.6 53.1 46.1 6.7 1.1 5.8 21.7 1.0 47.6 37.0 32.2 0.3 9.8 0.3 24.3 0.0 7.1 2.5 0.0 9.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.8 0.4 10.8 1.6 0.0 2.0 71.0 168.3 124.3 114.2 131.8 90.0 151.9 133.8 153.1 102.8 118.0 285.6 10.6 38.5 47.9 54.5 1.9 1.3 4.7 6.7 1.2 14.9 27.5 14.2 98.9 27.1 20.3 75.4 35.5 30.6 3.2 70.2 5.9 23.9 65.1 33.2 5.2 15.9 16.8 4.0 87.9 23.7 30.2 9.8 16.8 34.9 7.6 10.4 7.9 22.1 30.1 13.5 56.7 27.7 6.1 38.7 9.9 79.7 8.7 34.6 21.4 78.7 37.7 21.7 0.0 48.7 447.8 25.6 23.2 49.7 1.5 7.1 64.0 13.1 29.6 50.7 32.9 25.1 53.6 46.3 21.6 9.3 1.8 36.8 2.1 1.8 28.3 10.8 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.1" "Group enriched" "Detected in many" 8 "Adipocytes: 464.9;Endometrial ciliated cells: 377.3;Endothelial cells: 171.5;Glandular and luminal cells: 520.0" "Group enriched" "Detected in many" 4 "endometrial cancer: 122.8;ovarian cancer: 96.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "EFO-21: 108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB025594: , HPA068399: AB_2685981" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favorable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" 49.1 1.6 2.9 1.4 2.3 0.0 32.6 2.6 3.3 20.4 1.4 8.3 0.7 18.8 1.2 3.6 23.0 7.7 19.1 2.1 2.2 5.6 1.3 9.9 0.7 2.9 2.5 4.2 1.9 0.8 2.3 5.7 2.7 6.0 0.8 0.1 3.9 1.1 10.3 5.1 5.0 4.3 2.5 13.2 5.7 3.4 2.8 0.4 5.8 5.8 0.4 8.4 9.4 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 2.6 3.3 2.1 2.2 2.9 2.5 2.7 2.5 2.8 2.6 464.9 0.0 0.0 0.0 0.2 13.9 0.3 0.0 0.0 0.1 0.7 1.3 2.1 1.5 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 2.6 377.3 44.5 171.5 0.0 2.7 0.0 0.2 0.1 7.7 0.0 520.0 0.0 0.0 46.8 0.1 0.1 0.0 0.0 0.0 0.0 0.9 16.6 1.8 2.5 3.5 19.6 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 7.3 5.1 3.2 6.4 0.3 13.5 0.0 4.5 0.2 0.0 3.7 SOX18 ENSG00000203883 "SRY-box transcription factor 18" P35713 20 64047582-64049639 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.4" "Group enriched" "Detected in many" 9 "Adipocytes: 370.9;Endothelial cells: 212.4;Hepatic stellate cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 20.8;NB-4: 35.8;REH: 8.5;TIME: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073703 Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA073703: AB_2686628" "unprognostic (2.51e-1)" "unprognostic (3.23e-1)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (2.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.62e-1)" "unprognostic (3.45e-2)" "unprognostic (1.33e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-3)" "unprognostic (9.63e-3)" "unprognostic (1.41e-1)" "unprognostic (2.46e-1)" "unprognostic (5.40e-2)" 51.8 14.3 8.9 3.1 6.4 0.0 43.1 6.5 6.3 19.5 1.7 16.3 3.1 38.4 0.3 12.0 29.2 3.7 78.4 4.4 5.5 21.4 5.2 29.1 3.1 10.1 8.0 8.0 8.2 1.3 6.6 5.5 9.5 17.6 0.4 0.0 12.6 1.3 13.9 12.2 17.0 1.5 6.7 22.5 15.6 5.6 9.9 0.8 29.0 3.8 0.5 19.7 21.9 5.4 0.0 0.3 0.0 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 0.2 0.3 0.0 0.0 0.5 1.0 0.0 3.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 20.8 0.0 3.7 0.0 0.0 0.7 0.0 35.8 0.1 0.0 0.3 8.5 0.0 0.6 0.0 1.4 0.6 0.6 0.3 0.0 0.5 0.0 0.5 1.8 9.6 0.1 2.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.4 6.5 6.3 4.4 5.5 10.1 8.0 9.5 6.7 9.9 5.4 370.9 0.0 0.6 0.3 3.7 1.0 0.2 0.0 2.2 0.9 1.9 3.0 8.8 1.5 0.0 1.8 0.0 0.0 1.6 0.1 0.0 0.3 22.1 1.0 11.9 212.4 0.0 2.7 0.0 0.0 0.0 2.5 0.0 0.7 4.5 0.0 306.6 0.6 0.1 0.0 0.0 0.0 0.0 6.0 2.2 4.8 1.2 1.3 1.8 15.9 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 3.6 6.5 32.4 2.5 0.9 1.1 0.3 0.7 2.3 0.0 0.3 SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 42.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal keratinocytes: 61.2;Basal prostatic cells: 67.6;Basal squamous epithelial cells: 148.5;Endothelial cells: 115.1;Squamous epithelial cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 11.8;hTCEpi: 21.3;HUVEC TERT2: 25.2;TIME: 6.8" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.74e-2)" "unprognostic (7.26e-2)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (2.45e-3)" "unprognostic (2.38e-1)" "unprognostic (5.41e-3)" "unprognostic (4.84e-3)" 22.6 3.8 2.5 1.0 2.3 0.1 11.9 1.9 2.6 27.0 1.4 4.2 0.1 4.3 1.1 26.8 4.5 3.6 18.5 2.1 1.8 5.1 4.3 23.2 1.7 2.6 2.2 1.5 2.6 1.0 5.6 17.3 2.5 5.4 1.1 0.4 10.5 2.7 9.8 20.2 3.6 2.3 2.5 2.4 3.7 0.7 2.7 1.5 7.6 6.4 1.9 4.6 42.4 2.0 5.8 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.3 0.6 11.8 3.4 4.2 0.1 0.1 0.4 0.1 0.3 0.1 0.0 0.2 0.2 0.1 21.3 0.0 4.3 0.0 25.2 0.0 0.6 0.3 0.0 0.2 0.2 0.2 1.6 0.9 3.2 1.2 0.0 0.0 0.0 2.1 0.6 3.4 2.2 0.0 0.0 1.4 0.0 0.1 6.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.3 1.9 2.6 2.1 1.8 2.6 2.2 2.5 2.5 2.7 2.0 115.4 0.0 11.5 0.3 1.1 61.2 67.6 24.5 148.5 1.2 5.2 4.7 4.8 1.5 6.3 0.0 4.2 4.3 0.1 0.2 0.0 0.2 0.2 14.9 1.9 115.1 0.0 0.0 4.6 0.2 0.8 4.7 0.0 22.9 3.8 0.5 48.5 4.9 0.7 0.0 2.9 0.2 10.2 1.9 8.7 0.1 0.9 0.9 3.6 10.3 0.3 0.5 0.0 1.5 0.8 0.5 0.0 0.4 1.2 17.8 0.1 0.6 3.2 2.2 0.0 8.5 4.4 2.4 1.6 98.9 40.6 12.4 1.8 1.2 0.4 26.6 SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.6;lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" "B-cells: 149.9;dendritic cells: 37.4;NK-cells: 50.4;Plasma cells: 77.2;T-cells: 62.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 31.1;HDLM-2: 52.4;Karpas-707: 25.2;RPMI-8226: 16.3" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Mitochondria "HPA006162: AB_1857403, HPA067493: AB_2685851" "unprognostic (8.15e-3)" "unprognostic (2.25e-3)" "unprognostic (3.90e-3)" "unprognostic (5.72e-4)" "unprognostic (5.66e-2)" "unprognostic (3.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-2)" "unprognostic (2.88e-1)" "unprognostic (1.20e-9)" "unprognostic (9.12e-2)" "unprognostic (8.50e-2)" "unprognostic (3.66e-1)" "unprognostic (9.30e-3)" 1.7 0.8 0.7 25.0 0.8 6.6 1.2 0.8 1.6 0.6 1.0 3.5 2.9 0.9 0.8 0.9 0.7 2.9 0.6 0.8 1.1 0.9 1.6 4.4 54.6 1.8 1.2 0.4 0.3 0.2 0.6 1.2 1.5 0.9 3.9 1.0 2.6 0.5 0.2 1.6 15.6 1.0 1.3 27.8 5.1 1.5 2.1 6.8 1.3 0.1 55.8 4.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 2.4 0.0 0.3 31.1 0.0 0.0 5.2 0.0 0.0 0.1 1.8 52.4 0.0 0.0 0.0 0.6 0.2 4.4 0.1 0.5 0.0 0.5 0.6 0.4 0.0 0.3 0.0 25.2 0.6 0.0 0.0 1.5 1.3 0.0 0.0 0.1 2.8 16.3 8.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.1 0.3 1.3 0.0 0.0 9.2 4.0 1.1 2.2 0.7 0.0 0.1 3.5 12.0 23.1 7.3 25.6 97.5 22.8 25.3 8.3 71.0 11.5 15.0 33.4 15.1 10.6 0.5 22.5 10.6 0.7 0.8 0.8 1.6 0.8 1.1 1.8 1.2 1.5 1.3 2.1 1.5 1.6 0.0 2.3 3.9 149.9 0.9 0.0 0.2 0.0 0.7 0.3 0.5 0.5 0.0 0.8 0.0 8.4 0.1 37.4 0.1 0.0 0.0 17.2 0.5 0.2 1.1 0.0 9.7 5.0 0.0 0.2 0.8 1.5 0.1 0.0 0.2 2.2 0.9 11.4 0.0 5.0 0.1 0.0 8.4 8.6 4.8 0.0 13.2 7.2 26.2 13.7 0.5 50.4 2.5 2.8 0.1 0.1 1.2 77.2 0.1 0.0 0.4 2.4 1.7 0.0 0.2 1.0 1.2 0.4 0.7 1.1 0.3 62.1 0.3 0.2 0.2 SP140L ENSG00000185404 "SP140 nuclear body protein like" Q9H930 2 230327184-230403732 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA055864 Uncertain Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055864: AB_2682949" "unprognostic (1.44e-2)" "unprognostic (8.91e-2)" "unprognostic (4.44e-2)" "unprognostic (9.70e-3)" "unprognostic (2.07e-1)" "unprognostic (1.42e-2)" "unprognostic (1.22e-3)" "unprognostic (1.77e-1)" "unprognostic (3.87e-1)" "unprognostic (2.31e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-1)" "prognostic unfavorable (5.09e-10)" "unprognostic (9.15e-2)" "unprognostic (7.81e-2)" "unprognostic (9.49e-2)" "unprognostic (2.00e-3)" 9.4 9.7 3.4 18.8 3.6 13.6 8.5 3.2 3.9 7.6 4.5 8.5 11.0 7.1 6.4 7.7 7.8 8.6 5.3 3.2 3.6 9.6 15.1 11.3 24.8 5.0 4.1 11.8 4.4 1.6 3.4 10.6 4.6 6.9 9.4 1.9 12.5 6.0 5.1 3.0 16.3 6.5 4.0 25.6 8.9 1.7 4.6 12.8 5.4 4.4 20.2 10.7 8.3 4.7 13.6 2.4 3.1 9.6 15.8 17.2 17.2 19.7 22.6 16.0 25.5 1.3 15.3 10.3 20.2 15.4 28.4 2.3 0.0 14.1 26.0 27.1 0.1 18.5 11.1 10.0 29.7 15.1 19.9 14.4 7.6 23.6 15.4 13.7 23.7 15.5 4.5 9.4 29.0 7.5 22.7 21.2 10.7 9.1 7.0 7.8 28.9 8.3 14.5 16.9 0.6 2.9 4.7 9.5 11.2 19.0 14.2 15.9 26.1 14.2 10.5 8.2 15.2 13.7 9.2 14.8 18.9 15.4 25.2 21.4 7.7 4.1 15.4 10.7 18.7 29.5 14.1 12.5 8.3 32.6 19.5 17.4 7.4 23.0 12.5 3.3 9.7 9.6 3.4 3.6 3.2 3.9 3.2 3.6 5.0 4.1 4.6 4.0 4.6 4.7 30.5 32.1 35.6 1.6 58.8 1.9 13.8 14.6 1.8 2.7 9.3 9.1 4.2 11.5 21.7 16.5 18.8 9.9 40.4 16.8 0.0 22.5 16.3 7.2 16.9 23.3 3.6 9.9 2.4 18.3 17.6 14.6 23.0 14.3 42.3 18.7 13.9 9.4 20.4 0.0 2.0 10.4 16.2 17.1 11.4 5.9 4.4 23.9 5.4 29.0 13.9 1.8 49.4 2.5 1.4 20.0 20.3 8.2 33.7 10.3 14.5 3.3 28.3 1.7 6.6 18.8 14.0 0.8 1.9 7.7 2.6 11.9 47.1 31.7 8.5 23.2 SPAG4 "CT127, SUN4" ENSG00000061656 "Sperm associated antigen 4" Q9NPE6 20 35615829-35621094 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 90.1;testis: 32.0" "Group enriched" "Detected in many" 4 "Early spermatids: 177.9;Late spermatids: 139.8;Plasma cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 26.0;hTERT-RPE1: 18.4;U-87 MG: 47.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA048393, HPA061789" Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 55: Plasma cells - Humoral immune response" "HPA048393: AB_2680385, HPA061789: AB_2684609" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.09e-5)" "prognostic favorable (9.52e-8)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.05e-1)" "unprognostic (2.56e-3)" "unprognostic (1.21e-2)" "unprognostic (2.29e-1)" "unprognostic (4.77e-2)" "unprognostic (4.49e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.59e-2)" "unprognostic (1.66e-1)" "unprognostic (1.79e-1)" "prognostic favorable (6.66e-4)" 3.1 5.3 2.3 3.1 2.9 5.0 2.3 2.0 4.4 3.7 2.8 7.0 6.5 2.2 5.5 2.1 4.6 4.2 3.2 2.0 2.7 5.1 4.8 3.1 3.2 3.7 3.7 8.5 90.1 3.1 8.2 1.4 3.6 3.7 2.6 5.4 7.2 2.2 0.6 0.6 5.9 1.4 2.0 12.3 7.3 32.0 2.2 0.9 2.2 0.1 5.5 6.9 2.5 2.2 3.8 1.6 0.8 2.0 2.0 0.7 10.5 1.4 1.9 1.5 2.2 3.4 8.3 0.3 26.0 2.1 6.0 1.0 0.5 5.2 1.6 4.1 0.5 2.9 3.2 3.7 10.2 2.2 4.7 4.9 1.1 1.6 1.2 18.4 3.1 0.9 0.8 7.0 3.9 8.0 0.8 5.4 0.1 7.2 6.9 0.6 0.7 11.4 2.7 1.6 0.6 3.9 1.8 1.2 3.0 0.3 5.2 0.9 3.3 7.2 1.1 1.6 1.5 13.8 5.7 3.2 47.4 0.8 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.4 0.0 2.3 2.9 2.0 4.4 2.0 2.7 3.7 3.7 3.6 2.0 2.2 2.2 3.2 0.0 0.5 0.3 26.6 0.4 1.0 6.3 1.2 3.2 1.7 1.5 2.3 0.0 7.6 0.0 2.1 2.0 7.6 0.6 0.0 13.2 177.9 7.5 2.3 3.4 4.2 0.4 1.9 7.6 15.9 3.3 5.1 6.0 4.5 0.9 5.7 6.7 1.5 1.7 1.2 1.7 24.4 1.4 2.1 139.8 1.8 2.0 26.6 1.9 2.1 14.7 0.0 0.0 0.3 15.5 1.4 3.0 138.0 1.6 0.3 6.0 19.3 2.5 0.0 1.0 3.6 35.0 4.9 0.4 0.1 20.2 7.2 2.3 0.8 3.9 SPAG6 "CFAP194, CT141, FAP194, PF16, Repro-SA-1" ENSG00000077327 "Sperm associated antigen 6" O75602 10 22345445-22454224 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 63.5;fallopian tube: 49.0;testis: 96.3" "Cell type enhanced" "Detected in some" "Early spermatids: 228.6;Endometrial ciliated cells: 73.2;Respiratory ciliated cells: 266.4;Spermatocytes: 372.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "U-937: 105.6" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "midbrain: 11.1" HPA038440 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA038440: AB_10671742" "unprognostic (5.02e-2)" "unprognostic (9.52e-2)" "unprognostic (8.94e-6)" "unprognostic (2.21e-1)" "unprognostic (2.51e-2)" "unprognostic (4.91e-3)" "unprognostic (1.68e-1)" "unprognostic (2.38e-1)" "unprognostic (8.68e-2)" "unprognostic (1.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-3)" "unprognostic (3.10e-2)" "unprognostic (2.78e-4)" 0.0 0.0 4.2 0.0 4.0 0.4 1.7 1.9 1.4 1.7 63.5 0.0 0.0 0.2 0.4 0.0 49.0 0.0 0.1 3.3 5.0 0.3 0.1 7.0 0.1 17.6 16.1 0.1 0.3 1.8 14.6 0.0 9.9 1.0 0.0 5.8 0.0 0.0 0.0 0.3 0.0 0.0 16.3 0.0 0.0 96.3 6.4 0.4 0.1 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.9 2.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.1 1.7 0.8 0.2 0.0 105.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 4.2 4.0 1.9 1.4 3.3 5.0 17.6 16.1 9.9 16.3 6.4 10.1 0.0 0.0 4.8 0.0 0.1 0.1 0.1 14.0 0.0 0.2 0.5 0.3 0.6 0.0 24.5 0.0 0.0 0.1 0.2 0.1 1.9 0.3 228.6 73.2 0.4 0.2 0.0 0.0 7.1 0.0 0.0 0.7 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 3.1 0.0 16.2 0.0 0.2 51.4 5.0 0.5 1.8 4.7 0.0 0.3 0.0 0.5 6.0 0.4 0.0 4.9 0.3 1.8 0.0 1.4 266.4 1.2 0.0 0.0 3.7 372.6 4.8 0.0 0.1 0.0 0.5 0.1 0.0 0.1 SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4430.9;Endothelial cells: 2372.1;Peritubular cells: 2523.5;Sertoli cells: 4674.1;Skeletal myocytes: 2379.0;Smooth muscle cells: 2781.9" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 24.9;SuSa: 31.4;U-266/70: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Enhanced "Secreted in other tissues" NA NA 630000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" 755.6 129.5 664.6 124.5 810.9 0.5 532.1 612.4 1058.4 732.7 580.4 624.3 125.1 1244.5 443.8 308.1 754.5 487.9 600.2 744.6 723.5 72.5 25.0 481.1 99.1 655.7 730.9 286.8 91.8 128.0 197.8 315.4 663.4 584.2 187.5 95.2 228.3 999.2 244.8 130.2 280.1 1191.2 774.7 157.9 347.7 97.5 694.8 103.2 369.9 594.7 100.0 488.0 466.4 681.2 0.7 0.0 24.9 0.3 0.2 0.1 2.6 0.1 0.1 0.0 0.0 0.0 0.1 0.4 1.8 0.0 0.0 1.4 2.4 0.0 0.0 1.7 0.0 0.3 1.1 0.4 1.1 0.3 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.5 0.2 3.5 0.6 0.0 0.0 0.3 0.4 1.2 0.0 0.1 0.8 1.6 0.1 0.2 0.1 31.4 0.4 0.5 0.0 0.2 0.3 1.5 0.2 9.1 1.4 0.6 3.4 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 664.6 810.9 612.4 1058.4 744.6 723.5 655.7 730.9 663.4 774.7 694.8 681.2 4430.9 12.8 56.4 1155.7 6.2 46.3 187.2 0.6 59.7 10.7 24.4 251.6 334.2 4.3 43.3 7.3 2.1 2.2 8.6 0.0 13.7 0.8 11.8 34.9 935.8 2372.1 0.0 32.0 382.3 0.4 3.2 1413.1 6.1 46.7 7.6 1.4 899.5 9.1 9.2 3.3 450.1 0.0 0.0 5.3 55.2 47.0 659.5 31.6 56.9 261.4 0.0 179.4 0.0 210.6 53.8 0.1 0.0 2523.5 25.2 50.4 0.0 24.6 7.4 34.4 4674.1 2379.0 2781.9 5.7 7.9 56.8 39.9 2.5 26.9 38.8 0.0 124.2 SPATA9 "FLJ35906, NYD-SP16" ENSG00000145757 "Spermatogenesis associated 9" Q9BWV2 5 95652181-95698711 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 26.7" "Group enriched" "Detected in some" 18 "Early spermatids: 580.3;Late spermatids: 498.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 1.0;THP-1: 1.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA010848, HPA076967" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA010848: AB_1857422, HPA076967: " "unprognostic (4.46e-2)" "unprognostic (4.02e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (9.60e-2)" "unprognostic (5.69e-2)" "unprognostic (1.33e-2)" "unprognostic (2.08e-1)" "unprognostic (3.27e-2)" "unprognostic (7.58e-2)" "unprognostic (1.28e-2)" "unprognostic (3.08e-2)" "unprognostic (9.49e-13)" "unprognostic (3.39e-1)" "unprognostic (2.37e-1)" "unprognostic (1.26e-2)" "unprognostic (2.87e-2)" 1.1 0.3 0.1 0.1 0.2 0.2 0.2 0.4 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.2 0.2 0.2 0.4 0.3 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.1 0.4 0.1 0.0 0.1 0.2 0.0 26.7 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.3 0.1 0.2 1.0 0.0 0.5 0.0 0.2 0.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 1.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.3 0.1 0.3 0.2 0.2 0.2 0.1 0.2 0.6 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.9 0.3 0.0 0.0 0.1 580.3 0.3 0.5 0.2 0.0 0.0 1.9 0.0 29.2 0.4 0.0 0.2 0.0 0.9 0.0 0.1 1.3 1.7 2.6 0.1 0.0 0.3 0.0 498.7 3.7 0.2 0.0 3.7 0.1 0.5 2.1 14.1 1.7 0.0 0.4 3.4 0.1 0.3 0.1 0.0 0.2 0.4 0.0 1.7 0.3 7.7 3.2 0.0 0.1 4.2 0.1 0.6 0.2 0.2 SPDEF "bA375E1.3, PDEF" ENSG00000124664 "SAM pointed domain containing ETS transcription factor" O95238 6 34537802-34556333 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 140.7;salivary gland: 114.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 94.2;Breast myoepithelial cells: 61.1;Intestinal goblet cells: 315.1;Prostatic glandular cells: 72.7" "Cancer enhanced" "Detected in many" "prostate cancer: 388.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 288.4;OE19: 118.0;SK-BR-3: 192.2;T-47d: 154.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.9" HPA055707 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" Cytosol "HPA055707: AB_2682894" "unprognostic (2.98e-1)" "unprognostic (9.68e-2)" "unprognostic (2.84e-1)" "prognostic favorable (9.26e-9)" "unprognostic (1.57e-1)" "unprognostic (7.10e-3)" "unprognostic (2.56e-2)" "unprognostic (1.15e-1)" "unprognostic (1.63e-1)" "unprognostic (7.39e-3)" "unprognostic (3.48e-3)" "unprognostic (2.92e-1)" "unprognostic (6.16e-11)" "unprognostic (8.04e-2)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-2)" 0.4 0.1 0.5 1.4 0.5 0.1 36.6 0.8 1.1 28.0 0.0 18.4 11.6 9.0 0.5 2.2 6.3 2.4 0.4 0.5 0.2 0.1 0.1 1.1 0.0 0.3 0.4 0.1 0.6 0.0 0.2 0.0 0.2 140.7 10.2 0.0 114.8 0.1 0.3 9.3 14.3 0.6 0.1 0.1 35.4 0.3 0.5 0.0 0.1 0.0 0.0 1.0 0.3 0.5 0.0 30.9 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 288.4 0.3 0.4 0.0 118.0 38.6 0.1 0.0 0.3 0.3 0.3 2.1 0.2 0.0 192.2 0.0 0.0 154.0 0.0 0.0 0.0 0.5 0.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 1.1 0.5 0.2 0.3 0.4 0.2 0.1 0.5 0.5 0.8 0.0 2.2 0.7 0.3 0.1 13.3 20.7 0.0 0.0 94.2 61.1 0.3 5.7 31.7 0.0 0.0 0.0 1.4 27.1 0.0 2.6 1.1 6.2 0.7 0.6 5.4 0.0 0.8 1.2 0.0 0.4 28.1 18.7 0.0 0.2 0.4 0.0 0.0 0.0 0.6 315.1 12.2 0.0 0.2 5.5 0.0 0.9 3.6 0.0 0.0 0.0 0.0 0.0 0.2 20.2 12.3 0.0 0.1 72.7 5.7 0.0 2.9 0.0 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.3 0.8 0.0 30.0 11.5 SPECC1 "CYTSB, FLJ36955, HCMOGT-1, NSP" ENSG00000128487 "Sperm antigen with calponin homology and coiled-coil domains 1" Q5M775 17 20008865-20319026 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 217.1;Inhibitory neurons: 220.8;Microglial cells: 187.4;Oligodendrocytes: 317.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 42.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SiHa: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021421, HPA021430, HPA061073" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA 9800 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center, Cytosol" "HPA021421: AB_1857431, HPA021430: AB_1857432, HPA061073: " "unprognostic (1.13e-3)" "unprognostic (2.39e-1)" "unprognostic (1.98e-2)" "unprognostic (8.10e-3)" "unprognostic (8.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.29e-2)" "unprognostic (5.81e-2)" "unprognostic (6.23e-3)" "unprognostic (2.65e-1)" "unprognostic (3.15e-1)" "unprognostic (6.86e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" 12.5 9.6 30.8 7.3 35.1 23.6 9.2 24.1 43.7 6.1 22.3 15.1 9.8 12.8 4.7 9.2 8.3 14.8 5.0 41.4 21.4 4.7 1.2 5.7 5.3 32.8 25.8 16.6 4.8 3.3 6.4 3.6 24.5 6.1 10.0 6.1 6.2 5.0 5.1 3.6 10.5 9.5 21.0 13.5 10.3 22.8 41.1 3.0 5.2 2.8 5.2 4.6 4.3 47.3 26.2 37.3 15.7 7.2 14.7 6.9 29.1 10.0 12.4 12.4 21.4 67.6 17.1 1.5 45.3 11.4 24.3 21.1 10.7 33.4 3.7 12.8 18.5 14.5 34.4 10.5 4.9 1.3 5.6 10.6 36.9 10.2 24.9 46.8 0.0 4.4 1.0 15.1 10.4 24.0 0.3 5.3 14.5 17.0 6.3 11.8 49.5 23.6 32.2 11.4 7.1 6.9 75.7 35.6 13.9 62.2 26.3 9.1 0.3 0.5 21.1 0.9 30.8 5.4 11.7 0.9 19.1 12.6 6.5 42.1 15.8 33.0 2.2 8.4 3.2 1.8 1.5 3.4 26.6 1.4 1.0 1.4 11.1 13.0 7.9 4.6 0.6 5.5 30.8 35.1 24.1 43.7 41.4 21.4 32.8 25.8 24.5 21.0 41.1 47.3 28.7 22.4 14.7 170.4 5.7 5.5 12.5 22.0 10.8 7.4 5.8 4.7 10.3 7.2 21.1 18.4 68.8 5.5 10.2 56.8 9.8 30.9 100.0 40.1 44.1 13.1 7.7 82.5 217.1 36.3 11.5 18.6 34.1 64.1 116.4 29.5 3.9 0.2 22.0 0.0 220.8 54.8 12.2 12.4 15.9 54.5 5.0 29.0 21.4 187.4 84.7 13.6 11.3 125.2 317.8 67.7 24.7 44.8 7.0 19.7 25.2 3.6 18.1 31.4 59.2 7.3 81.3 73.8 68.9 5.9 2.6 2.2 10.0 87.8 27.4 21.5 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 SPINK2 HUSI-II ENSG00000128040 "Serine peptidase inhibitor Kazal type 2" P20155 4 56809860-56821742 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "epididymis: 5310.4" "Group enriched" "Detected in many" 10 "Early spermatids: 1217.2;Late spermatids: 1399.4;Spermatocytes: 1989.6" "Group enriched" "Detected in some" 5 "lung cancer: 1.3;testis cancer: 4.6;thyroid cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "NK-cell: 146.4" "Lineage enriched" "Detected in many" 7 "NK-cells: 146.4" "Cell line enriched" "Detected in some" 4 "U-266/70: 90.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB020824, HPA026813" Enhanced "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB020824: , HPA026813: AB_1857446" "unprognostic (5.56e-3)" "unprognostic (3.60e-1)" "unprognostic (7.54e-2)" "unprognostic (2.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.60e-1)" "prognostic favorable (2.82e-4)" "unprognostic (9.83e-2)" "unprognostic (6.62e-2)" "unprognostic (9.40e-3)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (4.10e-3)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.87e-2)" 0.5 0.1 0.1 1.1 0.2 13.5 1.3 0.1 0.6 1.3 1.8 2.8 1.9 0.3 5310.4 0.2 0.3 0.1 7.4 0.2 0.2 0.3 0.2 0.2 4.7 0.3 0.3 0.4 0.1 0.0 4.2 0.0 0.2 3.5 2.1 0.0 2.0 240.7 1.8 0.5 3.1 0.3 0.2 1.7 3.0 346.1 0.3 3.9 0.6 2.3 4.8 0.5 4.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.7 2.9 18.0 0.5 0.0 0.0 0.0 0.0 4.5 0.0 6.0 0.3 3.0 0.0 0.0 0.2 0.7 0.0 0.4 0.0 0.0 0.0 0.2 0.0 90.5 0.4 0.0 0.0 0.0 0.0 4.4 0.0 1.1 0.5 0.1 0.6 9.1 5.1 5.4 1.4 10.5 11.1 21.6 0.9 146.4 0.0 0.8 0.3 5.4 0.1 0.2 0.1 0.6 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.1 0.2 0.0 0.0 0.0 7.2 2.0 14.2 1.8 1.8 0.0 0.2 0.6 3.4 0.0 0.2 0.0 0.0 0.0 2.5 1.4 0.0 0.0 1217.2 0.2 0.1 1.6 1.8 32.4 0.3 0.0 0.3 0.8 0.5 0.2 1.3 0.3 0.0 0.0 0.1 0.0 0.2 10.4 0.0 0.0 3.6 1399.4 37.9 2.5 12.4 0.0 1.6 1.5 1.0 0.0 0.1 0.0 13.1 24.5 35.2 9.5 0.4 0.3 0.3 0.0 13.1 0.4 1.9 1989.6 149.9 0.1 0.3 0.0 16.8 0.0 2.6 2.6 SPINK8 ENSG00000229453 "Serine peptidase inhibitor Kazal type 8 (putative)" P0C7L1 3 48306842-48328341 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 11.5;breast: 44.1" "Group enriched" "Detected in some" 5 "Breast glandular cells: 22.1;Breast myoepithelial cells: 9.9" "Group enriched" "Detected in some" 10 "breast cancer: 8.6;glioma: 9.6;prostate cancer: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "eosinophil: 1.3;neutrophil: 1.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.7" "Cell line enriched" "Detected in some" 60 "SK-BR-3: 73.2" "Region enriched" "Detected in many" 9 "hippocampal formation: 73.7" "Low region specificity" "Detected in all" HPA053151 Uncertain "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA053151: AB_2682059" "prognostic unfavorable (8.47e-4)" "unprognostic (1.98e-1)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" 0.0 0.0 2.2 0.0 2.2 11.5 44.1 2.6 4.5 0.0 0.4 0.0 0.1 0.0 2.5 2.8 0.2 0.0 0.0 3.0 1.8 0.0 0.0 0.1 0.0 2.9 1.5 0.0 0.4 0.0 0.1 0.2 2.6 0.5 0.0 0.3 2.1 0.3 0.0 0.1 0.0 0.0 1.8 0.6 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.1 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 73.2 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 2.2 2.2 2.6 4.5 3.0 1.8 2.9 1.5 2.6 1.8 2.6 2.9 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 22.1 9.9 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 1.1 0.1 0.0 1.2 0.0 0.0 2.7 1.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 2.0 0.0 0.0 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.6 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 187.1" "Cell type enhanced" "Detected in many" "dendritic cells: 427.0;Endometrial stromal cells: 256.6;Extravillous trophoblasts: 355.8;Fibroblasts: 257.7;NK-cells: 1096.8" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 255.9" "Lineage enriched" "Detected in all" 5 "T-cells: 255.9" "Group enriched" "Detected in many" 5 "HHSteC: 303.8;HSkMC: 546.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" 66.2 40.4 4.0 18.8 7.7 19.5 50.6 15.6 3.9 161.4 3.5 51.5 18.5 187.1 4.4 40.6 49.7 32.2 35.5 3.5 0.8 37.1 79.1 63.0 3.9 2.9 1.7 34.4 18.7 0.9 15.1 19.2 3.5 111.8 7.2 0.7 28.8 8.4 19.1 38.3 63.5 42.7 0.2 26.9 43.8 4.7 1.8 1.8 16.3 6.6 1.0 68.4 94.0 1.5 0.4 0.6 0.0 0.0 10.2 79.0 3.0 6.2 5.0 0.8 1.0 0.0 0.1 1.8 9.7 26.9 0.9 45.0 0.0 0.2 0.0 0.3 0.1 0.2 3.0 12.7 303.8 0.2 1.5 546.6 0.0 0.6 0.0 0.0 0.0 4.1 0.3 9.2 0.0 0.3 5.3 12.2 3.5 9.7 0.7 1.0 3.3 7.9 0.0 0.0 1.7 1.1 1.1 0.0 2.9 1.7 0.4 1.5 0.1 0.2 0.9 20.5 0.0 1.3 2.7 0.6 0.1 6.5 0.0 3.7 0.9 1.0 255.9 1.1 5.5 0.7 33.1 105.8 0.4 1.0 14.4 96.8 9.8 50.4 2.2 42.9 0.1 123.2 4.0 7.7 15.6 3.9 3.5 0.8 2.9 1.7 3.5 0.2 1.8 1.5 9.8 0.0 5.6 1.3 6.6 36.8 2.0 82.5 2.2 3.7 5.1 3.8 4.0 24.3 43.0 1.8 0.0 3.4 427.0 9.7 1.9 3.8 0.2 12.7 256.6 5.7 13.8 4.0 8.4 1.3 355.8 257.7 10.7 6.6 6.3 0.2 15.4 40.4 12.8 0.0 0.6 9.7 73.2 5.8 15.4 0.5 29.8 9.5 26.6 6.5 9.2 0.9 1096.8 0.5 0.7 1.5 6.7 9.4 64.0 15.8 16.3 28.3 32.6 0.4 6.6 22.5 89.9 0.2 0.5 21.3 21.5 38.9 100.8 8.1 7.9 13.2 SPRY4 ENSG00000187678 "Sprouty RTK signaling antagonist 4" Q9C004 5 142310427-142326455 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.5;Alveolar cells type 2: 49.0;Endothelial cells: 32.8;Hepatic stellate cells: 37.1;Oligodendrocyte precursor cells: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 100.2;WM-115: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008086, HPA055471, HPA072661" Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" Cytosol "CAB008086: AB_2195454, HPA055471: AB_2682825, HPA072661: AB_2732207" "unprognostic (9.54e-3)" "prognostic unfavorable (7.12e-4)" "unprognostic (2.18e-1)" "unprognostic (1.16e-1)" "unprognostic (8.70e-2)" "unprognostic (3.23e-2)" "unprognostic (3.98e-3)" "unprognostic (1.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.44e-2)" "unprognostic (1.48e-1)" "unprognostic (9.89e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-3)" "unprognostic (3.63e-2)" "unprognostic (4.59e-2)" "unprognostic (8.21e-2)" 30.6 18.9 8.4 4.8 8.4 0.0 14.3 6.6 9.9 4.9 13.1 9.3 6.4 6.6 1.5 3.2 7.4 8.1 19.7 8.7 9.4 22.1 12.4 26.8 2.7 9.5 8.2 2.6 4.6 7.0 20.1 13.8 8.5 9.1 5.2 4.3 4.4 4.7 5.1 3.9 7.8 6.2 6.4 8.7 8.7 1.8 8.4 2.0 19.5 6.5 1.4 8.1 4.0 6.3 3.0 5.0 48.4 100.2 29.0 20.7 12.7 35.9 12.0 5.7 6.0 5.2 5.1 0.0 25.0 9.2 6.1 2.4 0.0 10.6 7.2 0.1 0.0 0.2 0.0 22.9 9.5 0.0 0.2 16.7 0.2 15.8 8.6 9.3 5.5 0.1 11.7 0.1 21.9 4.3 0.0 14.0 21.5 16.8 31.3 1.1 6.8 1.3 17.7 32.2 0.6 14.1 0.7 4.7 42.5 14.1 0.4 2.1 8.3 12.6 0.2 2.5 32.4 0.1 1.7 0.2 19.4 0.1 139.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 8.4 6.6 9.9 8.7 9.4 9.5 8.2 8.5 6.4 8.4 6.3 39.5 6.4 49.0 6.8 0.2 1.7 3.8 1.7 17.1 9.1 7.6 10.2 3.2 1.5 1.1 3.7 0.0 1.0 0.9 7.3 0.0 2.0 0.8 10.1 4.6 32.8 13.8 0.0 11.2 0.4 2.1 12.4 6.1 17.1 3.8 0.5 37.1 3.2 0.3 0.0 17.1 7.3 0.0 2.6 1.2 1.7 0.3 0.5 7.2 22.5 0.0 1.6 0.0 96.5 0.8 5.1 2.5 0.4 0.1 4.3 5.6 1.2 0.6 0.6 19.7 17.1 24.3 0.1 1.0 3.5 0.3 3.4 1.4 1.3 7.6 1.8 SPSB3 "C16orf31, SSB-3" ENSG00000162032 "SplA/ryanodine receptor domain and SOCS box containing 3" Q6PJ21 16 1776712-1793700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046602 Uncertain Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046602: AB_2679717" "unprognostic (1.18e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-3)" "unprognostic (1.82e-1)" "unprognostic (8.91e-4)" "unprognostic (1.07e-2)" "unprognostic (8.31e-2)" "unprognostic (5.65e-2)" "unprognostic (8.43e-2)" "unprognostic (3.41e-2)" "unprognostic (4.83e-2)" "unprognostic (5.25e-7)" "unprognostic (2.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-1)" "unprognostic (4.72e-4)" 27.1 44.7 27.9 7.7 28.5 21.2 25.8 37.0 40.2 27.1 24.0 28.9 14.7 21.3 3.3 36.1 23.7 10.0 28.6 26.4 27.2 24.3 41.8 20.6 12.4 29.7 28.3 37.1 44.0 11.4 15.3 10.3 27.4 23.3 5.1 9.6 26.4 15.5 88.5 48.4 18.8 5.6 28.3 23.3 27.8 17.3 29.2 26.1 19.7 31.0 7.8 23.2 28.7 31.8 7.3 9.1 9.7 13.4 13.6 12.5 19.8 10.6 11.0 11.5 12.6 8.4 20.0 3.2 17.4 6.0 4.5 13.9 4.8 10.9 1.8 14.7 15.0 5.2 13.9 10.4 20.2 4.5 12.0 11.3 26.8 7.2 8.4 17.1 17.5 22.1 7.8 15.4 5.4 24.0 16.3 16.0 8.1 10.8 7.1 29.7 5.9 26.7 10.6 1.3 12.9 16.6 12.6 27.8 29.4 6.9 16.1 18.0 16.1 5.6 10.6 10.5 5.5 26.1 28.2 8.9 5.4 8.9 5.9 112.3 44.8 83.4 67.9 41.8 81.2 46.8 63.1 61.7 42.3 44.2 43.6 46.6 91.5 45.7 37.2 42.8 100.7 48.4 27.9 28.5 37.0 40.2 26.4 27.2 29.7 28.3 27.4 28.3 29.2 31.8 74.2 38.5 32.1 29.7 56.1 98.4 53.3 72.7 60.3 74.1 64.1 83.7 0.2 40.0 54.9 55.2 39.6 63.0 104.2 68.6 52.8 50.8 46.7 29.4 32.3 46.1 48.7 50.5 18.2 47.6 74.8 42.8 65.2 37.8 35.4 76.2 57.1 62.5 31.8 90.9 19.4 57.8 38.7 42.7 72.2 91.6 77.0 44.8 76.5 24.4 61.6 76.0 99.9 24.6 30.7 45.3 83.2 74.9 61.2 50.5 96.3 50.6 37.2 89.8 39.5 34.0 45.3 23.8 39.7 37.0 128.3 64.4 87.8 33.2 52.7 54.3 SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 111.4" "Group enriched" "Detected in some" 4 "Distal tubular cells: 86.1;Proximal tubular cells: 202.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 17.5;HBEC3-KT: 8.9;hTERT-HME1: 12.4;SuSa: 14.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 17.1;hippocampal formation: 17.9;olfactory bulb: 7.5;pons: 8.0" "Secreted to blood" NA NA 2650000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.78e-2)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.81e-2)" "unprognostic (2.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (5.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.37e-3)" "unprognostic (9.78e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" 111.4 0.1 8.7 0.1 9.2 0.4 4.1 8.6 24.2 0.0 7.2 0.1 0.0 1.3 0.6 0.2 0.2 0.1 2.8 8.1 11.5 26.4 2.3 0.6 0.2 8.6 13.9 0.0 20.7 0.4 0.0 17.7 26.6 0.0 0.0 1.7 6.9 0.5 2.0 0.0 0.3 0.1 8.0 0.4 0.5 0.2 9.6 3.0 20.2 8.8 0.1 0.0 0.0 9.9 0.0 0.5 0.8 0.0 3.0 1.2 0.0 0.0 0.1 0.1 1.2 17.5 0.0 0.7 0.3 0.0 0.3 0.0 0.0 8.9 1.6 0.0 0.0 4.7 0.0 0.1 1.8 0.0 0.0 5.7 0.9 0.3 12.4 0.2 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 2.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 1.7 14.6 0.0 0.2 0.3 0.0 5.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.7 9.2 8.6 24.2 8.1 11.5 8.6 13.9 26.6 8.0 9.6 9.9 1.4 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 3.0 0.7 0.9 28.9 0.0 0.0 25.8 0.0 0.0 0.1 0.0 86.1 0.4 0.0 0.5 0.3 0.6 0.0 0.0 0.0 19.1 0.0 1.7 0.0 2.5 0.0 0.0 0.7 0.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 13.7 0.0 0.0 1.2 4.9 4.1 0.0 0.1 2.5 0.0 0.0 0.0 0.1 0.0 202.2 0.0 0.5 0.0 2.4 0.9 0.0 1.8 0.0 0.0 0.4 1.0 0.1 0.0 0.1 SRARP "C1orf64, ERRF, MGC24047" ENSG00000183888 "Steroid receptor associated and regulated protein" Q8NEQ6 1 16004236-16008807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.3;breast: 5.1;choroid plexus: 6.2" "Group enriched" "Detected in some" 4 "Breast glandular cells: 25.0;Distal tubular cells: 90.1" "Group enriched" "Detected in some" 4 "breast cancer: 7.7;endometrial cancer: 2.2;prostate cancer: 6.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.8" "Group enriched" "Detected in some" 13 "Hep G2: 7.9;SK-BR-3: 13.6;T-47d: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026676 Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA026676: AB_1853866" "unprognostic (8.55e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.68e-6)" "unprognostic (3.32e-2)" "unprognostic (1.09e-2)" "unprognostic (1.45e-2)" "unprognostic (1.41e-2)" "unprognostic (3.49e-1)" "unprognostic (8.25e-2)" "unprognostic (1.40e-2)" "unprognostic (1.81e-1)" "unprognostic (2.53e-1)" "unprognostic (1.65e-3)" "unprognostic (6.32e-2)" 0.1 0.2 10.3 0.2 9.7 0.7 5.1 8.9 11.3 2.3 6.2 0.1 0.2 1.1 0.1 0.2 0.1 0.2 0.9 8.8 9.3 1.5 0.1 0.1 0.3 9.4 9.4 0.2 0.2 0.0 0.0 0.1 10.0 0.7 0.0 0.8 3.1 0.0 0.2 0.6 0.1 0.0 8.6 0.2 0.3 0.2 11.2 0.0 1.2 0.0 0.0 0.1 0.0 9.2 0.3 0.1 0.3 0.4 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.4 0.6 7.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.6 0.5 0.0 0.4 0.3 0.3 0.1 0.1 0.2 0.2 0.3 0.2 0.0 0.1 0.4 0.6 0.3 13.6 0.2 0.4 4.3 0.4 0.2 0.4 0.3 0.3 0.1 0.2 0.5 0.2 0.2 0.2 0.6 0.8 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.2 1.8 0.3 0.1 0.1 0.0 0.0 10.3 9.7 8.9 11.3 8.8 9.3 9.4 9.4 10.0 8.6 11.2 9.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 1.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SRGN "PPG, PRG, PRG1" ENSG00000122862 Serglycin P10124 10 69088103-69104805 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Biomineralization" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 8096.7" "Cell type enhanced" "Detected in many" "dendritic cells: 2922.2;granulocytes: 2343.1;Kupffer cells: 1789.9;Langerhans cells: 6618.2;Macrophages: 3639.1;monocytes: 3188.2;Plasma cells: 1740.9;T-cells: 2235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 5714.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 5714.1" "Cell line enhanced" "Detected in many" "HL-60: 4442.1;NB-4: 2549.7;THP-1: 4346.8;TIME: 2609.1;U-937: 3546.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000759 Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA000759: AB_1079675" "unprognostic (3.61e-2)" "unprognostic (1.62e-2)" "unprognostic (2.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (4.50e-2)" "unprognostic (1.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.63e-1)" "unprognostic (8.22e-2)" "unprognostic (5.80e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.65e-1)" "unprognostic (2.32e-2)" "unprognostic (4.07e-2)" "unprognostic (4.08e-2)" 404.6 114.9 48.8 799.8 50.5 8096.7 136.4 55.5 99.6 93.2 70.1 101.8 77.9 63.5 25.9 91.0 96.8 316.4 111.9 48.2 67.8 98.3 239.4 347.3 437.2 82.4 59.3 30.7 68.4 131.6 62.1 355.6 67.8 58.9 118.9 15.5 40.1 57.4 37.5 18.9 111.4 219.4 65.5 362.8 95.0 18.3 64.7 228.9 72.7 117.1 314.6 508.3 46.1 71.0 5.3 43.0 0.2 0.4 768.1 749.7 1.2 94.9 63.9 235.1 283.5 0.1 18.2 9.1 117.4 4.1 134.4 1.1 0.0 20.6 799.9 535.7 0.4 87.1 29.8 0.3 312.7 4442.1 914.9 306.8 1.1 641.5 39.2 223.8 1227.8 13.3 82.5 419.9 1239.9 0.2 18.7 2549.7 0.7 0.1 84.6 2.4 2.3 446.7 0.6 6.0 0.3 0.8 2.3 0.6 16.0 0.0 2.2 4346.8 2609.1 187.9 12.9 3.8 20.1 486.4 508.4 57.3 112.2 3546.9 1.2 2349.8 1105.3 2730.6 474.9 774.6 313.4 73.5 228.5 362.8 583.0 39.0 125.5 268.4 5714.1 962.8 693.6 631.9 392.6 1590.5 48.8 50.5 55.5 99.6 48.2 67.8 82.4 59.3 67.8 65.5 64.7 71.0 1081.4 112.2 198.1 0.7 592.0 175.9 12.5 38.3 8.6 1.1 16.0 28.2 21.2 21.5 57.5 33.1 0.0 10.2 2922.2 2.9 0.0 4.2 4.1 4.6 15.0 566.8 1.8 277.8 0.2 9.8 10.2 87.9 70.3 6.6 2343.1 0.4 636.1 22.1 847.1 0.0 0.5 1.7 0.0 1789.9 6618.2 8.4 7.5 3639.1 556.7 80.6 3188.2 1.4 1292.5 0.0 0.2 1.3 1.2 18.0 1740.9 12.2 0.3 4.7 45.6 5.0 72.3 22.8 97.5 0.9 2.2 8.7 141.8 14.2 2235.9 1.2 5.5 18.1 SSB "La, La/SSB, LARP3" ENSG00000138385 "Small RNA binding exonuclease protection factor La" P05455 2 169791933-169812064 "Predicted intracellular proteins" RNA-binding "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004643, HPA017287" Supported Approved Nucleoplasm NA NA 93000 "Cluster 42: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "CAB004643: AB_425691, HPA017287: AB_1852672" "unprognostic (5.58e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "unprognostic (9.05e-3)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.99e-4)" "prognostic unfavorable (8.30e-8)" "unprognostic (1.09e-2)" "unprognostic (1.45e-2)" "unprognostic (9.81e-3)" "unprognostic (3.24e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (6.17e-6)" "unprognostic (9.92e-2)" "unprognostic (2.43e-1)" "unprognostic (1.21e-3)" "unprognostic (2.38e-2)" 114.1 75.6 53.7 75.8 54.9 105.3 76.0 55.5 72.8 59.3 63.3 61.7 49.2 68.6 82.0 51.6 61.0 58.1 69.0 53.8 58.0 74.5 68.5 55.9 93.3 55.5 58.3 68.9 40.2 80.0 64.6 73.6 55.6 78.2 57.1 55.2 49.9 58.8 62.3 46.6 49.3 61.5 55.3 62.7 49.8 41.1 55.2 70.2 81.7 52.9 81.2 88.4 51.2 55.2 189.0 109.3 231.2 173.5 244.9 226.0 287.8 226.8 150.8 208.2 192.7 332.9 201.7 419.8 251.7 149.8 188.9 197.9 315.3 198.6 283.9 231.2 258.4 505.9 138.0 323.4 218.6 410.8 181.5 175.1 187.1 265.0 156.8 170.6 235.4 156.1 599.0 95.5 442.4 149.5 273.6 428.2 373.3 180.7 110.5 267.9 245.7 304.6 266.3 205.6 219.8 168.0 179.9 132.4 262.9 223.4 152.5 292.0 213.9 151.1 180.1 153.8 221.9 110.3 227.3 355.9 149.2 381.4 168.2 83.4 47.3 59.9 71.9 81.6 104.2 89.8 100.9 92.1 56.8 75.8 90.5 97.0 7.9 93.8 104.5 60.6 100.9 67.2 53.7 54.9 55.5 72.8 53.8 58.0 55.5 58.3 55.6 55.3 55.2 55.2 143.0 86.6 79.9 21.9 107.9 91.6 229.2 308.7 83.6 114.7 78.1 126.7 91.9 77.2 168.9 112.2 27.1 212.4 111.6 33.6 187.9 206.6 20.3 235.3 188.4 131.5 73.0 154.2 25.4 146.7 212.4 133.5 46.9 101.2 205.0 111.4 92.8 77.0 185.7 136.3 26.8 82.7 240.1 86.8 91.4 49.7 184.2 111.7 80.0 15.0 113.4 152.7 84.5 20.1 21.5 113.2 47.8 186.9 78.7 199.2 40.2 194.9 371.1 91.4 216.9 183.7 194.8 154.4 156.7 68.5 88.4 165.4 128.4 183.3 100.0 155.9 SSC4D "S4D-SRCRB, SRCRB-S4D, SRCRB4D" ENSG00000146700 "Scavenger receptor cysteine rich family member with 4 domains" Q8WTU2 7 76389334-76409697 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.6;parathyroid gland: 7.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.0;Distal tubular cells: 3.9;Hepatocytes: 3.7;Spermatogonia: 3.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "EFO-21: 6.7;Hep G2: 9.6;SuSa: 10.7;U-2 OS: 25.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062611 Uncertain "Secreted - unknown location" NA NA 980000 "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 7: Non-specific - Mitochondria" "HPA062611: AB_2684807" "unprognostic (3.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (2.83e-6)" "prognostic unfavorable (7.08e-4)" "unprognostic (3.52e-2)" "unprognostic (3.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.49e-2)" "unprognostic (8.49e-3)" "unprognostic (3.18e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (2.59e-1)" "unprognostic (3.90e-1)" "unprognostic (2.56e-2)" "unprognostic (1.73e-2)" 0.7 0.3 0.2 0.0 0.4 0.0 0.3 0.0 0.2 0.3 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 2.6 0.4 0.1 0.0 0.2 0.2 0.7 2.2 7.0 2.6 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.1 0.0 0.5 0.0 0.0 1.0 0.0 0.3 0.0 0.8 0.2 0.0 0.0 0.1 1.0 0.5 0.0 0.0 10.7 0.2 0.0 0.0 0.0 25.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.2 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.5 1.6 0.1 0.0 0.5 0.0 0.6 0.4 1.4 1.4 2.1 0.0 0.0 11.0 0.0 0.3 0.0 0.2 3.9 1.9 0.1 0.5 0.1 0.3 0.0 0.0 1.6 1.7 1.4 0.4 0.0 0.4 0.0 0.7 1.1 3.7 2.8 1.7 1.4 0.1 0.0 0.6 0.0 0.4 0.9 0.9 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.4 0.1 0.4 0.0 0.4 0.4 1.3 0.0 0.2 0.0 0.8 0.6 0.6 3.5 1.0 0.0 0.3 0.1 0.6 0.2 0.4 SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.3;Fibroblasts: 27.0;Leydig cells: 18.0;Peritubular cells: 15.8;Skeletal myocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 26.9;BJ: 22.7;fHDF/TERT166: 27.5;hTERT-RPE1: 23.2;U-87 MG: 27.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" 13.1 2.2 2.6 3.6 4.6 0.1 8.8 3.0 2.1 23.0 1.8 33.6 1.9 39.7 3.9 5.7 17.0 12.9 17.6 1.8 2.1 3.6 1.7 9.1 1.3 3.9 2.6 14.5 1.8 0.3 17.6 1.9 4.0 8.8 2.8 1.1 3.4 12.8 3.6 5.6 8.7 20.1 2.2 11.1 9.8 2.6 3.6 2.0 3.8 2.8 0.5 10.6 15.9 2.1 0.1 1.4 0.5 0.0 3.3 26.9 0.0 22.7 5.5 3.7 4.6 0.4 0.0 1.2 0.3 27.5 1.1 0.0 0.0 0.0 1.9 0.1 0.3 5.6 1.5 0.0 5.2 0.1 9.6 12.3 0.0 5.4 0.0 23.2 0.0 0.7 0.2 0.3 0.6 0.1 0.1 0.5 0.9 0.0 0.2 0.7 1.2 0.3 2.5 0.0 2.9 0.4 0.4 0.0 0.5 0.5 0.4 1.2 7.9 1.0 1.3 1.1 3.8 0.4 0.0 0.1 27.8 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.6 3.0 2.1 1.8 2.1 3.9 2.6 4.0 2.2 3.6 2.1 3.5 3.2 0.6 4.2 0.3 1.9 0.3 0.3 0.0 5.3 0.8 1.1 2.8 0.0 0.1 0.0 2.1 0.1 0.4 0.8 1.9 0.1 0.6 1.5 19.3 3.3 0.0 0.0 1.5 0.0 0.1 27.0 2.0 0.9 0.0 0.5 2.2 0.0 1.2 3.3 1.1 0.4 0.0 1.0 3.8 1.3 18.0 2.0 1.8 2.8 0.7 2.1 0.0 0.0 0.3 0.1 0.3 15.8 0.3 0.3 4.6 0.2 0.7 1.9 0.0 32.1 6.8 0.9 1.1 0.4 1.8 0.0 0.5 0.9 1.4 0.2 SSTR2 ENSG00000180616 "Somatostatin receptor 2" P30874 17 73165010-73176633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.1;Enteroendocrine cells: 35.7;Sertoli cells: 32.9;Smooth muscle cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 12.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007264 Uncertain Supported Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA007264: AB_1080053" "unprognostic (2.13e-3)" "unprognostic (2.61e-3)" "unprognostic (7.43e-2)" "unprognostic (9.37e-3)" "unprognostic (6.25e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-3)" "unprognostic (7.46e-2)" "unprognostic (2.96e-1)" "unprognostic (6.55e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.04e-7)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (3.71e-3)" "unprognostic (2.95e-2)" 2.5 3.6 8.4 0.9 8.9 0.9 1.7 7.2 8.7 0.5 0.3 0.8 1.4 0.7 1.6 0.4 1.1 0.6 0.8 9.0 4.3 5.3 1.4 0.4 1.1 2.2 5.1 0.3 0.7 0.3 2.9 0.1 8.6 1.4 1.1 2.2 0.7 1.4 0.7 0.6 0.9 0.8 2.6 6.1 3.1 0.3 4.8 0.5 1.1 0.2 1.3 0.9 0.7 6.8 0.2 0.3 0.3 0.7 0.1 0.1 0.4 0.1 0.2 0.3 0.3 0.2 0.3 0.3 0.2 0.1 0.9 0.3 0.0 0.1 0.1 0.4 0.6 0.3 0.8 0.3 0.0 0.2 1.5 0.1 0.0 0.1 0.0 0.2 0.0 0.4 0.2 0.7 0.0 0.3 0.2 0.8 1.0 0.1 0.4 0.4 0.4 0.3 0.2 0.3 12.5 0.9 0.2 0.2 0.1 0.5 1.5 0.2 0.1 0.2 1.4 0.4 0.2 0.5 0.2 1.0 0.2 0.3 0.2 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 1.2 0.2 0.2 0.2 0.1 0.1 8.4 8.9 7.2 8.7 9.0 4.3 2.2 5.1 8.6 2.6 4.8 6.8 4.9 6.4 2.7 1.6 0.5 1.1 3.2 0.0 0.0 59.1 3.7 2.5 3.6 1.5 1.3 1.8 4.2 0.7 0.9 0.1 0.0 0.2 7.0 2.1 1.7 11.3 35.7 0.0 17.1 0.0 0.7 14.3 3.1 4.9 2.5 3.0 3.9 1.0 1.0 6.7 8.4 8.2 0.0 2.4 3.0 5.7 0.9 2.4 5.4 1.9 1.7 2.4 1.0 2.0 0.7 0.4 0.1 0.7 5.8 5.4 0.6 18.0 0.7 4.8 32.9 10.0 56.0 0.9 1.9 0.3 1.1 1.0 1.4 0.6 0.5 3.3 SSTR3 ENSG00000278195 "Somatostatin receptor 3" P32745 22 37204237-37212477 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6;lymphoid tissue: 11.1;testis: 7.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.3;Late spermatids: 2.0;Microglial cells: 1.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 10 "T-cells: 1.1" "Group enriched" "Detected in some" 11 "RPMI-8226: 23.3;SCLC-21H: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022647 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022647: " "unprognostic (1.63e-2)" "unprognostic (5.58e-3)" "unprognostic (1.32e-2)" "unprognostic (3.18e-2)" "unprognostic (7.03e-2)" "unprognostic (6.26e-5)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (1.90e-2)" "unprognostic (8.95e-2)" "unprognostic (3.88e-3)" "unprognostic (2.93e-1)" "unprognostic (1.51e-7)" "unprognostic (1.55e-1)" "unprognostic (1.24e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-2)" 0.1 0.3 2.2 1.0 2.2 0.4 0.0 1.2 6.4 0.0 0.0 0.2 1.3 1.1 0.0 0.0 0.1 0.0 0.0 1.9 2.2 0.1 0.0 0.0 1.8 6.8 3.5 3.3 1.8 0.0 2.6 0.0 6.7 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.5 1.0 1.2 0.6 0.2 7.8 7.6 11.1 0.0 0.0 0.9 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 8.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.9 0.0 0.0 0.0 0.0 0.1 0.2 2.2 2.2 1.2 6.4 1.9 2.2 6.8 3.5 6.7 1.2 7.6 2.3 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.4 0.0 0.0 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 47.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.8;Oligodendrocyte precursor cells: 94.0;Oligodendrocytes: 108.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 54.4;RT4: 47.0;SK-MEL-30: 40.8;U-266/84: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" 17.5 47.4 17.1 4.6 26.9 2.3 8.5 16.4 20.1 5.4 7.9 5.0 1.0 9.9 0.9 2.7 10.4 8.1 4.2 16.0 24.7 2.8 9.8 14.6 9.1 24.7 22.6 10.1 3.9 0.4 12.8 17.7 23.1 6.7 2.6 31.0 7.1 0.5 12.4 6.1 6.9 3.5 20.6 20.0 5.6 10.8 23.6 5.0 27.9 3.5 4.4 20.8 5.9 41.6 0.3 27.0 2.5 54.4 22.0 11.8 8.0 5.9 18.0 5.6 5.0 0.5 19.6 0.7 0.2 10.2 2.5 1.0 3.6 6.4 7.0 0.2 3.2 0.6 1.1 1.0 17.6 0.4 7.8 6.9 0.8 2.1 0.8 10.1 13.7 7.4 0.8 30.2 18.3 1.8 1.9 3.1 0.2 9.6 0.0 3.5 17.0 11.0 2.9 47.0 3.8 3.8 0.2 0.1 40.8 5.4 0.2 1.1 4.5 0.1 2.7 0.1 0.4 30.0 42.5 0.5 4.2 5.6 27.7 0.6 0.8 0.1 0.6 3.0 0.8 1.1 0.3 0.4 0.5 0.7 0.3 0.3 0.6 0.6 2.4 0.2 0.1 0.3 17.1 26.9 16.4 20.1 16.0 24.7 24.7 22.6 23.1 20.6 23.6 41.6 8.5 86.6 112.8 37.5 29.1 5.6 27.6 20.5 1.2 56.6 3.1 2.3 1.9 40.0 33.9 3.7 58.4 0.4 48.3 0.2 3.9 12.0 12.3 9.0 27.8 8.1 6.7 0.4 46.9 16.6 1.1 21.7 6.1 8.5 34.8 35.2 29.6 21.1 35.6 72.3 60.2 0.1 12.2 45.4 18.1 12.0 8.1 24.9 32.0 45.9 20.1 56.0 12.3 94.0 108.4 6.2 0.1 1.9 19.5 6.8 0.0 3.7 10.7 45.2 0.0 21.3 5.0 8.4 16.1 0.2 3.8 0.3 28.9 6.3 0.1 8.3 ST6GALNAC2 "SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM" ENSG00000070731 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2" Q9UJ37 17 76565377-76586956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Early spermatids: 501.1;Late spermatids: 1763.3" "Cancer enhanced" "Detected in all" "melanoma: 22.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "neutrophil: 47.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 47.0" "Cell line enhanced" "Detected in some" "BEWO: 25.4;HaCaT: 33.8;HBEC3-KT: 28.5;hTCEpi: 73.1;MCF7: 36.4;SK-MEL-30: 112.5;T-47d: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (8.93e-3)" "unprognostic (5.86e-3)" "unprognostic (1.67e-2)" "unprognostic (5.18e-3)" "unprognostic (3.37e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.95e-1)" "unprognostic (5.37e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.57e-1)" "unprognostic (5.17e-3)" "unprognostic (3.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" 5.6 2.9 1.0 1.9 1.1 1.0 12.2 1.2 1.4 14.9 33.0 13.8 1.0 4.8 10.3 16.4 50.5 1.9 4.5 2.0 1.6 9.6 1.2 17.5 0.6 5.4 6.7 1.2 6.3 7.5 2.1 6.0 4.1 11.1 6.0 52.8 11.3 10.2 18.3 51.6 4.8 2.3 4.2 3.7 7.1 33.9 2.6 1.5 25.2 18.5 4.8 9.5 14.5 2.7 2.6 0.0 0.0 0.0 0.5 0.0 25.4 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.5 1.7 0.1 33.8 0.3 28.5 0.0 0.0 0.0 0.0 1.2 0.0 1.2 0.0 0.0 0.0 73.1 0.1 9.0 3.8 0.1 0.0 0.0 0.0 0.4 36.4 0.0 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 9.8 0.5 0.0 4.1 0.1 112.5 1.3 23.4 0.7 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 2.9 5.2 0.0 1.8 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 47.0 0.2 0.4 0.0 0.0 0.4 1.0 1.1 1.2 1.4 2.0 1.6 5.4 6.7 4.1 4.2 2.6 2.7 0.2 0.0 1.5 2.6 0.8 32.9 44.0 104.2 23.9 7.9 0.4 1.5 5.1 7.2 21.0 0.0 27.1 12.5 0.0 2.4 0.0 0.3 501.1 4.5 1.1 3.9 0.0 0.0 0.5 0.0 21.1 2.0 4.6 0.6 1.3 0.0 7.9 1.5 3.0 0.0 1.3 4.8 8.2 5.0 6.9 1763.3 7.5 3.8 65.8 1.0 2.7 84.9 0.0 0.0 0.2 0.1 0.5 7.2 0.2 15.2 0.7 0.5 39.3 79.7 19.7 7.3 3.4 7.6 4.6 28.8 30.3 10.5 2.2 0.0 1.6 37.6 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 ST6GALNAC6 "SIAT7F, ST6GALNACVI" ENSG00000160408 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" Q969X2 9 127885321-127905408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 258.8;Intestinal goblet cells: 100.6;Paneth cells: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "NK-cells: 23.7;T-cells: 25.6" "Cell line enhanced" "Detected in all" "ASC diff: 157.1" "Low region specificity" "Detected in all" HPA018890 Approved "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018890: AB_1857531" "unprognostic (2.27e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (5.71e-2)" "unprognostic (1.36e-1)" "unprognostic (4.84e-2)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.24e-3)" "unprognostic (3.31e-2)" "unprognostic (3.29e-1)" "unprognostic (1.10e-2)" "unprognostic (9.85e-2)" "unprognostic (3.46e-2)" "unprognostic (2.67e-2)" 95.8 37.4 155.5 21.4 156.0 17.7 68.7 129.5 177.8 48.7 120.2 75.5 9.5 48.6 50.0 35.0 67.2 28.4 61.3 165.6 130.9 50.1 63.5 66.7 27.5 133.4 137.2 83.0 52.8 32.4 26.0 22.0 128.3 40.2 126.4 16.0 28.3 41.5 46.0 37.4 35.2 38.0 128.3 64.1 43.9 17.6 140.6 14.9 32.5 40.2 23.1 56.6 42.6 134.6 12.0 9.2 18.9 36.9 157.1 91.9 7.4 29.7 69.6 43.7 35.9 16.3 10.0 13.8 13.4 68.1 28.4 21.9 25.6 23.7 19.0 50.9 14.0 13.4 19.0 16.7 48.1 3.3 18.9 94.9 27.5 34.0 15.1 61.6 40.9 11.9 12.2 14.6 54.9 9.9 8.4 19.3 9.1 12.3 17.5 24.6 27.0 14.3 32.2 2.4 13.1 21.3 21.4 8.8 7.6 12.3 9.3 29.0 26.7 27.6 16.3 30.5 15.8 18.4 9.8 21.5 24.5 4.1 8.7 3.3 1.2 0.1 25.3 1.9 18.5 5.3 16.5 18.8 1.8 3.9 10.0 13.7 0.6 23.7 5.0 2.1 25.6 12.4 155.5 156.0 129.5 177.8 165.6 130.9 133.4 137.2 128.3 128.3 140.6 134.6 1.3 3.2 4.3 13.1 10.5 23.2 17.2 15.7 9.1 22.0 0.9 0.6 8.7 8.6 9.5 0.0 6.2 4.3 11.7 258.8 0.0 0.3 2.5 0.8 1.7 20.6 38.5 26.1 11.5 0.4 7.7 26.6 3.6 1.4 7.0 0.2 46.8 28.5 11.6 25.2 10.7 100.6 18.3 10.0 35.6 9.4 66.5 4.1 24.9 8.4 3.2 58.7 46.4 5.5 3.8 0.3 178.3 60.9 8.9 20.5 0.3 0.0 16.1 8.5 85.5 41.2 31.9 1.4 4.8 10.3 26.9 3.6 17.7 0.5 84.7 18.6 ST8SIA4 "PST, PST1, SIAT8D" ENSG00000113532 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4" Q92187 5 100806933-100903282 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 73.3;Kupffer cells: 92.4;Langerhans cells: 149.3;Microglial cells: 101.2;monocytes: 97.5;Plasma cells: 73.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 91.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 41.1;HDLM-2: 69.3;Karpas-707: 57.2;NB-4: 27.9;RPMI-8226: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051126, HPA053995" Approved Approved "Golgi apparatus" "Intracellular and membrane" NA NA 980000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA051126: AB_2681352, HPA053995: AB_2682336" "unprognostic (2.25e-1)" "unprognostic (2.04e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-2)" "unprognostic (1.14e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-1)" "unprognostic (5.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.49e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.80e-7)" "unprognostic (6.07e-2)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" 5.8 1.9 2.2 14.0 2.4 7.6 2.2 1.6 2.4 1.9 2.5 3.3 3.2 1.6 0.5 1.1 1.8 5.0 2.3 1.8 4.5 0.7 2.6 5.7 12.3 4.8 3.6 0.5 0.8 1.0 0.6 11.1 5.2 1.3 4.2 0.6 1.2 0.8 0.8 0.8 4.5 2.8 2.7 11.8 3.0 0.4 4.3 9.5 2.0 1.7 10.3 5.5 1.1 4.5 0.0 6.1 41.1 0.0 2.6 3.9 1.0 0.0 0.0 0.0 0.3 0.0 0.0 3.3 0.1 0.0 1.0 0.1 1.0 0.1 0.1 69.3 0.0 2.5 0.4 0.0 0.0 13.0 5.0 3.2 0.0 0.1 0.1 5.3 7.7 10.1 0.0 57.2 2.4 0.6 18.6 27.9 0.3 0.0 0.3 10.3 0.7 44.8 0.2 0.0 0.9 0.0 0.0 0.0 0.1 0.2 0.0 11.6 2.7 0.4 0.2 0.0 0.6 18.6 20.3 3.9 1.0 15.8 5.1 58.0 18.5 22.9 13.1 21.7 9.9 11.1 8.7 11.1 12.2 9.9 5.4 10.1 91.7 10.6 24.0 3.7 17.4 12.2 2.2 2.4 1.6 2.4 1.8 4.5 4.8 3.6 5.2 2.7 4.3 4.5 35.8 6.4 14.1 1.6 49.7 8.3 0.4 2.1 2.2 0.6 0.9 0.9 2.3 1.5 10.1 0.0 0.0 9.4 44.0 0.0 1.9 0.2 0.2 0.9 1.6 28.4 0.0 8.2 6.8 0.0 42.4 5.0 1.1 0.3 24.1 0.1 7.1 0.1 22.6 0.0 73.3 0.2 4.1 92.4 149.3 0.7 0.0 57.5 14.2 101.2 97.5 3.2 34.0 4.5 1.6 0.0 0.0 0.4 73.8 0.2 0.0 0.3 16.6 0.9 13.1 1.2 3.7 0.5 0.8 0.4 5.5 19.2 37.7 0.7 0.0 0.5 ST8SIA6 SIAT8F ENSG00000148488 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" P61647 10 17315421-17454595 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;lung: 5.9" "Cell type enriched" "Detected in some" 5 "Microglial cells: 137.7" "Cancer enhanced" "Detected in some" "breast cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "HMC-1: 208.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011635, HPA072708" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA011635: AB_2194921, HPA072708: " "unprognostic (4.86e-3)" "unprognostic (7.01e-2)" "unprognostic (5.85e-3)" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (2.32e-1)" "unprognostic (3.23e-2)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (1.07e-3)" 0.7 0.3 5.8 0.4 4.1 1.8 5.2 3.2 3.6 0.3 2.4 0.6 0.3 0.4 4.6 0.5 0.3 0.5 3.4 2.9 3.3 0.8 1.0 5.9 0.2 5.4 10.5 0.4 0.2 0.0 0.3 1.1 4.6 1.5 0.4 0.4 0.6 0.2 0.2 1.0 0.4 0.3 3.6 0.6 0.3 0.3 8.0 0.3 0.4 0.8 0.4 0.2 0.4 4.3 0.2 0.2 0.1 1.7 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.6 0.6 0.0 0.1 0.3 0.3 0.5 0.1 0.0 0.0 0.4 0.2 25.9 0.4 0.5 0.0 0.0 208.0 0.1 0.0 0.2 0.1 1.8 0.0 0.3 4.6 0.4 2.5 1.9 1.1 0.4 2.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 9.3 0.2 1.1 0.0 3.6 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.1 1.7 0.5 0.5 0.5 0.1 0.2 0.1 0.3 0.3 0.2 0.3 0.3 0.4 1.0 0.7 0.3 0.2 0.8 0.2 5.8 4.1 3.2 3.6 2.9 3.3 5.4 10.5 4.6 3.6 8.0 4.3 0.6 0.0 0.0 2.6 0.1 0.6 0.1 0.2 0.0 0.0 10.0 3.9 0.8 0.0 0.2 0.0 0.0 0.0 5.5 1.2 0.0 0.0 0.5 0.1 0.0 10.9 0.0 25.5 3.0 0.0 0.0 0.3 0.0 0.8 10.2 2.8 26.7 0.0 0.1 0.0 4.4 0.0 0.0 0.9 0.0 0.6 0.0 0.2 8.8 137.7 0.2 0.0 8.2 1.5 1.1 0.1 0.1 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.3 0.0 0.0 0.0 2.4 0.1 0.0 0.1 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.7" "Cell type enhanced" "Detected in all" "Early spermatids: 520.2;Hepatocytes: 660.0;Intestinal goblet cells: 717.9;Late spermatids: 2055.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 617.7;OE19: 1316.9;SK-BR-3: 427.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 13000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA026661: AB_1857538" "prognostic favorable (6.92e-4)" "unprognostic (2.07e-1)" "unprognostic (8.03e-2)" "unprognostic (1.74e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "unprognostic (4.16e-1)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (4.24e-3)" "unprognostic (8.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-2)" "unprognostic (1.04e-1)" 11.8 178.2 35.1 17.7 37.6 10.3 62.1 39.2 41.8 71.9 40.9 180.6 48.5 27.3 102.9 52.0 26.4 59.5 72.5 33.9 34.1 50.1 709.7 37.7 14.5 38.0 33.0 31.0 212.6 73.2 36.2 40.2 38.2 86.2 188.1 18.7 94.5 30.9 66.7 62.6 66.0 26.7 29.9 20.2 266.9 184.3 34.4 15.6 47.9 157.9 21.8 24.5 41.1 35.7 51.2 15.3 7.7 28.7 9.8 9.6 98.3 5.6 26.2 17.3 17.3 209.8 36.7 4.4 16.7 19.2 42.3 31.8 23.4 46.8 20.2 28.3 9.0 5.9 11.1 217.6 35.2 1.6 10.0 6.6 127.0 19.1 26.7 47.2 17.8 10.0 12.1 21.5 3.9 617.7 4.8 11.1 3.4 1316.9 20.1 4.5 13.3 3.4 23.5 61.4 13.0 10.1 8.6 427.4 73.3 32.8 235.5 6.3 13.6 17.0 11.4 6.0 10.1 22.2 19.8 7.5 4.3 5.6 6.5 12.9 2.6 16.0 1.6 1.1 1.2 4.2 1.5 1.7 1.2 2.4 1.6 1.6 21.7 7.5 0.6 2.6 2.1 1.1 35.1 37.6 39.2 41.8 33.9 34.1 38.0 33.0 38.2 29.9 34.4 35.7 10.6 35.3 74.1 8.1 18.1 31.5 76.3 41.0 25.0 10.5 163.3 125.3 45.3 270.2 76.4 55.2 22.9 212.8 17.1 362.8 123.3 70.7 520.2 26.5 6.8 18.5 302.2 22.9 11.6 94.3 93.1 21.1 372.1 25.3 25.4 10.1 30.0 660.0 26.4 33.7 13.9 717.9 85.5 26.0 34.4 2055.8 26.1 12.3 16.0 5.6 7.7 64.4 7.2 8.0 11.8 93.9 398.9 25.2 13.3 150.9 73.5 58.0 34.5 16.6 6.6 11.3 19.6 101.2 22.7 30.2 55.0 352.2 15.6 7.7 440.7 132.7 STARD8 "ARHGAP38, KIAA0189" ENSG00000130052 "StAR related lipid transfer domain containing 8" Q92502 X 68647666-68725842 "Metabolic proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.9;Endothelial cells: 26.5;Hepatic stellate cells: 18.5;Kupffer cells: 13.7;Langerhans cells: 14.9;Macrophages: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "classical monocyte: 1.6;intermediate monocyte: 3.2;myeloid DC: 3.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 18 "dendritic cells: 3.4;monocytes: 4.7" "Cell line enhanced" "Detected in many" "HEL: 16.0;K-562: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060788 Uncertain NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA060788: AB_2684365" "unprognostic (2.00e-1)" "unprognostic (8.98e-2)" "unprognostic (1.56e-3)" "unprognostic (4.94e-3)" "unprognostic (1.73e-1)" "unprognostic (2.61e-2)" "unprognostic (2.77e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (5.09e-3)" "unprognostic (9.72e-2)" "unprognostic (9.58e-2)" "unprognostic (5.19e-3)" "unprognostic (4.89e-3)" "unprognostic (9.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.07e-2)" 13.4 4.4 8.1 6.0 6.9 3.4 10.3 6.4 6.8 6.3 5.7 4.0 1.4 7.1 4.7 3.4 8.9 5.2 12.5 6.3 6.3 14.7 6.5 20.7 4.1 13.5 7.5 3.3 5.1 2.6 8.9 8.8 8.1 9.2 1.5 0.6 2.7 8.5 6.8 2.8 4.3 6.1 8.2 11.1 4.2 0.8 8.4 1.6 10.3 6.5 1.9 6.6 4.5 6.6 0.0 1.8 2.8 1.4 0.0 0.0 2.1 3.8 7.9 2.1 1.6 0.0 0.4 0.0 9.6 1.6 0.2 0.0 0.8 0.0 3.5 0.0 0.5 16.0 1.4 0.2 0.3 0.0 0.0 1.3 0.0 5.4 0.0 6.1 9.9 0.0 20.4 0.0 5.3 0.8 0.0 9.5 1.6 0.0 0.3 0.0 10.1 5.4 9.5 0.0 0.0 0.7 0.1 0.9 0.3 5.6 1.3 2.2 7.0 9.6 4.0 3.1 3.7 0.0 0.0 0.0 7.2 6.6 5.7 0.0 1.6 0.0 0.0 3.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.7 0.1 0.0 1.8 8.1 6.9 6.4 6.8 6.3 6.3 13.5 7.5 8.1 8.2 8.4 6.6 27.9 0.0 6.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.2 0.3 8.5 0.0 1.8 0.0 0.0 0.3 0.1 0.0 1.9 0.0 0.1 1.2 1.6 26.5 0.0 2.1 0.3 0.0 0.2 3.0 0.5 1.1 7.0 0.3 18.5 6.5 3.6 0.0 0.8 0.0 0.0 13.7 14.9 0.0 0.3 13.9 0.0 9.4 2.4 0.3 0.0 0.5 0.5 0.8 0.0 0.0 0.9 0.1 0.0 2.4 2.2 0.4 0.0 2.8 3.5 0.1 0.2 0.2 1.4 0.1 0.6 0.2 0.0 0.1 STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;testis: 29.2" "Cell type enhanced" "Detected in many" "dendritic cells: 139.0;Early spermatids: 275.1;Excitatory neurons: 85.9;Late spermatids: 66.0;NK-cells: 108.1;Plasma cells: 83.8;T-cells: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.6;T-cells: 121.2" "Cell line enhanced" "Detected in some" "Karpas-707: 58.8;U-266/70: 32.9;U-266/84: 12.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA001860, CAB013108" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB013108: , HPA001860: AB_1080104" "unprognostic (3.90e-5)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (6.45e-4)" "unprognostic (3.77e-2)" "unprognostic (4.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (2.65e-1)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" 4.7 4.0 3.4 11.5 4.4 15.7 3.0 0.1 10.4 1.6 0.1 2.8 4.5 1.9 2.6 1.4 1.6 5.1 23.0 3.8 3.6 4.5 9.5 7.8 18.0 2.1 1.7 1.5 2.2 1.2 15.0 2.6 2.0 1.8 3.4 2.1 2.2 1.3 1.2 1.1 6.9 1.4 0.6 15.5 4.4 29.2 3.4 9.0 2.4 1.0 10.4 5.9 1.8 4.5 0.1 1.7 1.1 0.0 0.0 3.6 0.3 0.6 2.2 0.6 2.2 0.4 0.8 0.0 0.2 2.8 1.6 0.9 0.0 4.7 1.2 0.0 0.8 1.3 0.0 0.0 0.6 0.0 0.1 1.5 2.3 1.1 0.5 0.1 0.0 6.0 0.0 58.8 0.2 0.0 3.5 0.0 0.3 0.0 0.9 0.0 0.0 4.3 0.2 0.1 0.1 1.2 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.1 1.6 0.0 32.9 12.8 0.0 1.2 0.0 0.1 15.7 0.4 0.1 121.2 0.8 107.3 1.8 71.6 101.2 0.6 1.0 68.1 95.8 2.8 76.6 0.8 9.3 28.1 55.3 3.4 4.4 0.1 10.4 3.8 3.6 2.1 1.7 2.0 0.6 3.4 4.5 2.9 3.2 4.2 2.6 14.5 1.3 0.6 2.9 0.0 0.9 0.9 1.1 20.3 4.3 0.6 1.8 8.4 0.4 139.0 0.5 0.0 0.6 275.1 1.1 0.5 1.2 0.0 10.5 85.9 0.2 2.9 2.9 8.6 0.7 1.3 0.8 1.1 1.1 1.1 0.0 59.4 0.3 0.0 6.3 10.6 66.0 0.3 14.4 5.4 7.5 6.3 0.0 108.1 6.0 2.4 0.1 0.3 0.4 83.8 1.0 0.0 0.8 2.4 0.2 0.0 0.6 3.7 8.3 1.2 0.4 1.7 0.5 137.4 0.1 0.3 0.7 STAT5A "MGF, STAT5" ENSG00000126561 "Signal transducer and activator of transcription 5A" P42229 17 42287547-42311943 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Lactation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 78.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 101.0;HEL: 153.5;HMC-1: 85.2;K-562: 262.4;MOLT-4: 163.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003860, HPA027873, HPA042128, HPA049883, HPA051156" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Cytosol" "CAB003860: AB_562347, HPA027873: AB_10603893, HPA042128: AB_2677864, HPA049883: AB_2680931, HPA051156: AB_2681366" "prognostic favorable (5.87e-4)" "unprognostic (3.09e-3)" "unprognostic (2.31e-2)" "unprognostic (1.76e-1)" "unprognostic (1.43e-1)" "unprognostic (3.41e-3)" "unprognostic (2.15e-1)" "unprognostic (6.22e-2)" "unprognostic (3.33e-1)" "unprognostic (6.82e-3)" "unprognostic (2.76e-1)" "unprognostic (2.11e-1)" "unprognostic (3.85e-2)" "unprognostic (5.74e-2)" "unprognostic (1.90e-2)" "unprognostic (1.98e-1)" "unprognostic (5.49e-3)" 78.9 40.6 4.3 28.9 5.7 52.1 48.8 5.3 4.8 19.1 5.4 24.0 8.6 17.8 5.7 9.9 19.0 13.9 13.9 3.6 7.5 13.9 8.1 23.3 37.5 8.0 7.6 22.5 12.2 2.4 10.5 7.3 7.4 15.4 9.1 1.2 15.7 13.7 23.8 18.4 22.4 14.3 6.7 29.8 14.0 4.9 7.7 24.4 13.3 13.8 27.1 24.1 15.4 8.6 3.9 4.9 0.5 0.0 35.7 17.5 0.4 2.1 8.6 4.0 2.3 0.0 3.7 0.3 9.0 8.5 0.2 0.3 0.8 0.3 1.1 101.0 0.0 153.5 9.3 1.3 15.5 13.5 85.2 36.8 2.1 1.7 2.0 0.0 12.3 2.0 262.4 0.1 2.3 0.1 163.5 64.7 1.4 2.5 0.0 4.5 1.1 13.8 1.1 2.6 0.3 0.0 10.0 3.9 17.8 0.9 2.5 13.9 7.2 8.0 2.6 3.9 0.1 0.2 0.1 0.0 1.0 25.4 2.5 9.8 15.1 7.9 10.3 18.6 14.4 8.2 18.3 15.2 18.7 6.6 18.0 15.0 18.3 17.4 24.9 6.6 14.5 12.9 4.3 5.7 5.3 4.8 3.6 7.5 8.0 7.6 7.4 6.7 7.7 8.6 14.0 0.0 10.6 2.6 18.7 7.4 3.8 4.5 5.7 2.9 35.8 24.5 29.6 5.7 3.4 5.5 0.0 1.2 17.7 5.5 5.9 5.0 0.4 7.2 5.2 21.2 0.0 33.2 0.2 13.6 2.9 15.3 5.1 11.9 22.8 6.8 6.1 3.3 21.4 0.0 1.3 4.2 0.0 24.5 41.3 3.5 32.6 31.8 8.8 5.6 41.0 3.9 8.2 2.5 5.0 9.6 8.1 41.0 12.5 12.2 1.8 14.4 8.4 0.7 6.6 13.7 10.2 0.0 0.9 4.4 7.7 1.4 29.2 7.7 6.5 7.0 STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 130.3;skeletal muscle: 248.5;tongue: 154.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.1;Ductal cells: 7.9;Glandular and luminal cells: 5.1;Plasma cells: 7.0;Proximal enterocytes: 19.5;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 140.7;U-266/70: 62.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" 109.7 5.3 4.3 7.3 4.0 19.9 11.8 3.5 6.3 7.0 2.9 29.0 9.6 9.3 3.2 15.1 13.7 12.8 52.7 4.0 7.0 10.0 130.3 14.1 1.3 6.7 5.4 10.0 12.0 7.9 1.7 16.8 6.2 20.7 26.4 4.0 4.7 13.9 248.5 1.5 26.1 28.0 5.6 2.2 15.5 9.7 5.6 1.3 2.6 154.7 2.1 22.1 4.5 5.6 15.9 9.9 2.0 10.0 46.3 13.9 12.7 21.9 21.6 12.0 12.6 12.6 17.9 0.0 13.1 25.8 26.2 9.2 9.6 6.1 7.4 52.4 3.6 1.7 18.2 16.5 4.8 9.5 10.5 7.1 24.0 10.2 8.2 32.4 0.9 0.0 0.6 140.7 23.7 13.0 0.6 7.4 2.5 24.1 7.2 0.0 3.8 9.9 8.0 17.2 2.6 17.7 12.9 20.2 0.3 5.0 4.9 3.7 3.9 11.6 5.9 29.4 12.5 62.8 17.1 0.0 19.6 7.5 5.4 0.1 2.6 5.7 2.0 3.1 1.1 0.1 2.4 2.4 2.5 0.0 0.5 0.9 0.3 4.4 1.2 0.3 0.8 1.3 4.3 4.0 3.5 6.3 4.0 7.0 6.7 5.4 6.2 5.6 5.6 5.6 0.0 0.0 0.5 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.2 9.1 0.0 7.9 0.0 2.8 1.5 0.1 0.0 0.4 0.0 3.9 1.4 1.0 2.6 5.1 0.0 0.3 0.0 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 3.3 2.9 0.0 7.0 0.5 19.5 0.3 6.6 0.0 0.0 1.1 3.0 0.2 0.0 1.1 0.0 0.8 0.3 0.3 1.4 0.9 STEAP1B ENSG00000105889 "STEAP family member 1B" Q6NZ63 7 22419444-22727613 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.9;choroid plexus: 4.5" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 129.9" "Cancer enhanced" "Detected in many" "melanoma: 5.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 67 "memory B-cell: 8.4;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 84 "B-cells: 8.4" "Group enriched" "Detected in many" 5 "hTEC/SVTERT24-B: 80.7;HUVEC TERT2: 105.0;K-562: 45.4;WM-115: 112.0" NA NA "Cluster 37: B-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (7.35e-2)" "unprognostic (2.42e-1)" "unprognostic (1.72e-2)" "unprognostic (1.34e-3)" "unprognostic (3.96e-2)" "unprognostic (2.18e-1)" "unprognostic (2.31e-5)" "unprognostic (2.29e-3)" "unprognostic (4.96e-2)" "unprognostic (7.37e-3)" "unprognostic (7.38e-2)" "unprognostic (1.27e-2)" "unprognostic (2.85e-10)" "unprognostic (1.06e-4)" "unprognostic (3.46e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-3)" 1.0 0.5 1.6 1.1 3.3 0.1 0.8 2.1 2.7 1.2 4.5 0.7 0.1 0.2 0.4 0.6 0.3 0.7 0.5 1.9 2.3 0.2 0.2 0.4 1.6 3.4 2.4 0.1 0.3 0.1 0.3 1.2 3.7 0.5 0.5 0.3 0.4 0.6 1.2 0.4 0.3 0.6 1.4 1.8 0.4 2.3 2.6 1.1 0.2 0.6 1.6 0.8 1.7 6.9 13.5 0.1 8.3 0.0 6.3 9.2 0.0 9.7 1.1 0.2 0.3 0.0 0.3 1.7 2.7 16.9 2.8 0.0 12.3 0.1 0.4 0.5 1.1 0.0 0.3 0.0 0.9 0.0 0.1 10.6 0.0 80.7 0.2 9.7 105.0 0.4 45.4 4.5 0.0 0.0 0.1 0.0 16.8 0.0 0.1 1.7 0.0 5.4 0.1 0.0 0.0 0.2 0.3 0.0 6.4 1.0 0.1 0.0 12.3 1.0 0.4 11.5 0.1 1.1 9.8 12.2 17.7 0.0 112.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 3.3 2.1 2.7 1.9 2.3 3.4 2.4 3.7 1.4 2.6 6.9 2.4 0.0 0.0 1.6 4.6 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 5.1 0.4 0.1 1.3 0.0 0.0 9.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.5 11.8 2.1 0.0 0.0 0.3 0.5 1.5 0.0 1.3 3.6 5.6 11.9 0.0 0.0 7.5 129.9 0.4 0.0 0.4 0.8 0.1 0.0 0.0 0.1 0.2 0.0 0.0 2.7 7.4 11.6 0.1 0.1 0.1 0.0 5.1 0.2 0.1 STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 163.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 163.6" "Group enriched" "Detected in some" 6 "HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" 113.7 46.3 1.0 31.7 0.9 7.1 68.6 2.8 1.5 21.3 17.0 13.3 3.8 17.9 7.8 15.4 36.1 22.7 24.1 1.4 1.0 11.8 24.3 67.5 7.2 1.2 0.9 4.4 10.6 16.0 13.0 15.3 0.8 60.0 9.2 1.9 26.8 10.6 13.4 19.3 10.6 29.3 0.4 5.4 10.6 13.4 1.1 7.8 53.1 16.6 5.1 34.3 22.7 1.1 4.9 0.0 0.1 0.1 0.1 1.9 0.3 0.0 0.3 0.0 0.1 0.1 23.6 0.1 0.1 0.0 0.4 18.7 0.1 0.0 0.1 0.0 0.1 0.1 7.9 0.1 0.1 0.1 0.2 122.1 0.1 0.4 0.9 0.0 0.0 0.1 0.3 0.4 0.0 3.0 0.1 0.5 0.1 1.0 0.0 0.2 0.1 0.3 0.0 0.3 0.2 0.2 119.7 9.9 0.0 0.1 0.8 0.0 0.1 0.4 0.3 166.4 0.1 0.1 0.1 0.1 0.2 0.9 0.2 0.4 13.5 1.4 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 163.6 0.2 0.1 0.3 0.0 3.2 1.0 0.9 2.8 1.5 1.4 1.0 1.2 0.9 0.8 0.4 1.1 1.1 77.2 54.5 402.5 0.0 0.8 9.4 5.8 8.6 1.8 1.8 21.6 8.3 9.1 0.0 152.8 0.0 2.1 0.4 1.1 0.4 0.0 14.6 23.8 14.6 20.5 14.7 0.0 0.0 0.5 9.6 10.6 39.8 1.1 51.2 16.4 0.0 15.4 0.7 2.8 0.0 0.8 0.2 16.2 7.2 7.4 10.9 114.9 12.2 5.4 6.5 19.0 2.7 0.0 1.0 0.1 18.6 0.0 9.1 0.2 49.3 0.1 0.1 72.8 0.3 460.2 9.6 255.3 0.9 0.3 1.5 18.8 10.9 3.1 57.7 0.2 16.6 STING1 "ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173" ENSG00000184584 "Stimulator of interferon response cGAMP interactor 1" Q86WV6 5 139475533-139482935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Host-virus interaction, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 25.3;Cardiomyocytes: 27.7;dendritic cells: 17.0;Hofbauer cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 64.4;EFO-21: 83.8;HDLM-2: 200.5;THP-1: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038116, HPA038534" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA038116: AB_2675841, HPA038534: AB_2676067" "unprognostic (1.45e-1)" "unprognostic (4.10e-3)" "unprognostic (1.29e-1)" "unprognostic (2.23e-2)" "unprognostic (2.70e-2)" "unprognostic (1.71e-2)" "unprognostic (7.66e-2)" "unprognostic (2.77e-2)" "unprognostic (6.30e-2)" "unprognostic (1.01e-1)" "unprognostic (5.69e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.59e-8)" "unprognostic (9.18e-3)" "unprognostic (4.14e-2)" "unprognostic (4.45e-2)" "unprognostic (1.34e-1)" 38.9 9.3 4.6 18.4 5.0 16.9 26.2 4.4 5.4 32.6 12.8 16.6 6.7 25.0 6.8 21.5 36.2 11.9 35.7 4.3 4.9 17.3 5.5 48.1 15.0 5.5 4.9 21.9 5.4 3.3 11.8 12.9 5.1 20.7 11.6 0.3 24.5 15.5 7.5 15.5 19.0 18.7 5.3 37.8 11.6 3.1 6.0 12.4 20.2 8.5 27.1 21.7 28.4 4.8 2.9 0.7 0.2 0.0 4.0 12.0 0.2 15.3 64.4 7.6 24.4 0.0 18.8 0.0 83.8 49.0 1.9 10.8 0.4 22.9 4.8 200.5 3.3 13.5 6.6 0.8 7.5 4.1 0.8 16.2 1.2 4.6 5.7 12.8 27.8 1.4 3.9 58.3 33.6 0.0 2.2 24.1 0.1 0.8 4.7 0.7 6.1 18.0 9.4 7.0 5.8 0.0 6.5 5.3 16.0 0.6 0.7 73.3 17.2 1.9 1.3 6.8 5.6 0.0 20.0 0.1 0.3 56.2 11.3 16.6 60.9 0.1 56.9 40.0 29.3 0.6 57.4 47.8 55.6 0.3 40.3 35.0 5.0 90.6 17.5 19.2 65.3 60.6 4.6 5.0 4.4 5.4 4.3 4.9 5.5 4.9 5.1 5.3 6.0 4.8 25.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.0 0.0 0.0 0.0 0.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.6 8.4 0.0 0.0 0.0 0.0 0.0 0.0 67.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.8 5.8 0.0 0.0 0.0 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042079-172188224 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5;lymphoid tissue: 45.2" "Cell type enhanced" "Detected in all" "dendritic cells: 107.7;Kupffer cells: 91.4;NK-cells: 171.0;T-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 143.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 16000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 14.9 5.7 3.1 37.1 3.6 76.5 11.4 18.4 5.6 4.5 3.5 8.5 8.4 4.9 1.7 5.6 4.7 13.2 7.6 3.1 4.0 5.9 6.2 18.4 44.1 6.2 4.4 2.5 7.2 3.1 4.1 17.2 5.8 4.4 6.9 1.2 4.7 3.5 5.0 14.2 16.0 7.8 5.4 45.2 11.1 14.0 6.4 20.6 5.3 5.5 25.0 14.9 5.2 7.0 22.2 20.2 12.7 18.8 14.7 18.1 31.5 28.4 24.0 20.2 18.9 10.6 28.6 26.8 14.6 35.6 42.3 25.4 5.7 35.1 13.5 35.0 9.3 32.1 8.2 6.1 20.2 32.7 36.4 17.4 7.5 27.4 23.1 7.5 18.3 10.4 3.0 36.2 14.7 35.7 23.5 73.4 5.0 11.3 16.1 38.2 9.9 17.7 8.2 27.6 8.3 10.2 16.4 22.5 77.9 15.6 8.2 68.7 24.8 22.3 11.3 15.8 15.5 30.2 48.4 17.1 29.4 49.8 143.3 16.7 26.5 23.4 36.5 46.3 26.9 10.0 19.3 26.3 22.5 8.1 11.0 20.0 48.9 16.9 71.8 7.1 26.7 44.0 3.1 3.6 18.4 5.6 3.1 4.0 6.2 4.4 5.8 5.4 6.4 7.0 35.8 3.2 11.2 1.6 40.5 6.6 8.4 7.2 5.7 4.3 3.3 3.7 3.8 5.7 6.1 1.8 6.2 4.1 107.7 11.8 1.9 4.5 2.5 3.5 4.6 23.9 12.0 11.8 8.5 6.2 27.2 9.3 20.9 7.1 28.4 3.6 18.2 2.3 36.3 47.1 7.9 19.9 2.0 91.4 43.8 3.2 2.8 61.3 8.8 32.8 49.8 2.1 171.0 10.1 14.4 10.7 11.8 1.5 42.8 11.7 6.5 2.0 6.1 2.2 13.1 5.1 10.2 5.3 7.8 2.6 4.1 5.1 81.4 11.4 5.3 10.7 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favorable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 15.2 24.9 17.6 11.8 17.5 15.0 16.2 16.3 20.5 14.0 19.5 20.0 17.3 13.8 20.8 22.8 18.1 13.0 19.0 16.5 16.8 26.5 43.2 14.3 17.6 17.9 17.5 14.8 30.9 22.7 19.8 9.2 16.9 20.3 13.5 7.9 20.0 10.9 14.4 17.3 17.8 9.9 17.4 21.2 24.2 27.7 18.6 20.5 19.3 8.2 14.5 17.8 14.8 16.5 14.1 18.8 15.7 13.2 40.0 40.0 17.9 17.8 23.6 14.3 14.7 21.2 31.0 8.3 24.4 32.0 23.4 14.5 18.5 30.0 7.8 20.0 19.8 17.7 15.4 19.1 34.9 17.6 20.1 40.1 48.1 20.8 57.4 29.8 17.9 18.7 23.1 21.5 26.8 27.1 19.4 38.0 14.5 25.7 10.3 18.1 17.5 24.9 32.2 16.1 12.3 14.6 5.8 25.5 39.0 11.2 27.4 36.4 13.7 20.6 14.0 16.4 17.4 25.9 12.1 19.5 22.9 18.4 18.3 1.6 7.0 5.3 4.9 3.8 5.5 7.2 6.0 9.2 6.8 6.0 6.1 7.9 4.1 14.5 3.1 5.8 7.3 8.7 17.6 17.5 16.3 20.5 16.5 16.8 17.9 17.5 16.9 17.4 18.6 16.5 11.8 6.4 5.6 3.6 22.4 9.8 18.1 32.6 24.5 7.9 31.8 31.8 9.5 24.3 19.7 7.3 16.7 24.0 23.6 27.6 68.4 40.3 87.2 21.4 13.3 14.0 25.8 36.0 2.2 58.5 25.0 15.8 17.3 12.9 8.2 17.9 12.5 43.7 28.4 13.5 2.7 38.7 16.2 27.1 17.6 70.3 15.2 17.8 21.4 0.0 38.4 22.1 44.3 4.0 6.8 33.3 44.3 13.5 27.6 18.6 58.9 80.2 19.6 19.1 0.0 11.9 19.2 43.1 9.6 28.2 11.2 12.9 22.1 33.6 34.2 20.8 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023302-132075943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 70.0;epididymis: 56.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 55.2;dendritic cells: 42.7;NK-cells: 53.5;Syncytiotrophoblasts: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 140.1;U-937: 144.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No 360000 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: AB_2684163" "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 6.0 2.5 1.0 15.2 2.7 70.0 6.0 1.7 1.3 6.8 2.5 11.5 9.6 46.6 56.3 13.1 7.4 5.6 1.4 0.7 1.5 3.5 5.2 7.2 26.2 0.8 0.8 2.1 3.7 23.5 5.0 25.2 0.7 20.0 11.6 0.2 7.3 35.8 0.9 7.8 6.9 38.1 0.6 13.2 12.2 2.2 3.8 41.3 3.7 1.2 23.5 11.8 7.4 0.7 32.9 11.3 1.3 0.0 5.2 4.9 72.0 1.0 4.0 0.5 0.6 30.1 29.0 44.6 19.4 7.3 22.1 36.5 80.8 51.1 0.0 39.1 66.6 64.6 25.9 28.4 4.7 135.3 5.1 6.9 30.0 0.1 33.7 15.1 14.2 60.0 29.2 40.4 12.2 29.0 140.1 124.9 64.4 22.0 4.3 99.9 39.7 57.9 32.6 51.8 26.6 29.6 19.2 17.0 0.9 54.9 22.0 35.4 0.3 12.8 13.7 39.0 47.9 31.0 52.0 49.8 11.7 144.8 6.5 59.1 9.5 31.6 22.8 12.4 22.4 14.5 15.2 19.6 11.3 12.6 19.7 20.6 18.2 41.0 22.7 4.2 7.2 20.4 1.0 2.7 1.7 1.3 0.7 1.5 0.8 0.8 0.7 0.6 3.8 0.7 0.9 22.4 15.6 0.0 24.7 0.0 36.4 0.0 6.8 0.0 5.9 10.9 1.3 5.7 8.1 11.0 0.0 55.2 42.7 6.5 3.9 4.5 0.6 7.4 1.8 1.7 1.2 12.8 2.0 7.1 34.7 9.6 15.3 17.9 11.4 0.5 1.4 4.4 11.8 0.0 1.4 4.8 0.0 8.8 0.0 0.4 3.4 17.3 0.0 2.8 13.5 0.0 53.5 0.0 0.2 10.9 4.0 2.2 14.5 33.6 1.9 1.5 6.6 0.0 6.6 6.7 3.6 1.8 2.5 16.1 0.0 59.1 27.4 0.6 6.5 18.2 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 19 "Oligodendrocyte precursor cells: 306.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 13.6;SK-MEL-30: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 1.3 11.2 5.9 0.6 9.5 0.0 1.2 13.2 3.1 1.0 1.0 2.3 0.5 0.5 2.6 0.3 0.8 1.5 1.0 3.5 14.4 3.4 0.1 1.2 0.0 11.7 24.4 2.5 2.6 0.1 8.1 0.1 17.0 1.0 0.3 2.6 0.9 0.8 0.2 3.7 0.7 0.4 10.4 0.3 1.2 1.0 14.0 0.1 8.7 0.5 0.0 1.7 1.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.2 4.4 13.6 1.2 0.5 0.0 0.0 48.6 0.2 0.0 0.0 0.1 0.0 0.5 0.7 0.4 1.0 0.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 9.5 13.2 3.1 3.5 14.4 11.7 24.4 17.0 10.4 14.0 10.1 0.2 0.0 2.6 8.5 0.0 1.5 0.2 1.4 0.0 1.8 1.3 0.5 0.5 0.0 1.0 1.8 0.0 0.0 0.0 0.1 1.9 1.8 6.9 0.2 0.5 0.1 0.0 0.0 4.6 2.7 0.0 2.7 0.0 0.7 0.0 4.2 0.0 0.0 0.1 0.0 5.2 0.0 2.0 0.0 1.0 10.5 0.9 0.2 16.0 0.0 0.0 4.0 0.0 306.6 0.7 5.5 0.0 4.1 0.0 0.3 0.0 4.1 0.2 1.0 0.0 5.4 0.5 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.0 0.6 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168247595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 159.9;Inhibitory neurons: 142.9;Oligodendrocyte precursor cells: 153.3;Oligodendrocytes: 359.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 80000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 19.4 6.7 20.1 14.0 25.8 5.1 8.4 25.3 25.1 12.0 52.9 26.3 32.0 7.3 14.5 36.3 6.4 18.1 15.8 16.0 18.6 9.0 1.9 7.6 22.2 28.8 25.8 6.6 25.6 13.7 8.2 2.3 31.9 28.7 32.4 27.8 67.9 11.5 2.7 6.3 18.6 11.7 20.8 8.6 31.8 48.5 25.6 29.1 6.9 7.6 23.5 24.8 9.5 37.0 19.1 10.9 40.9 12.9 28.1 37.5 4.0 45.0 33.8 29.6 27.8 0.2 59.9 51.1 12.2 30.5 25.5 46.6 26.7 34.4 37.1 16.2 16.4 21.2 11.8 42.9 52.3 30.5 2.1 29.1 52.8 35.1 36.5 38.5 21.2 41.3 0.5 0.0 67.0 11.4 51.6 13.0 30.3 41.0 24.3 72.1 16.0 4.8 27.9 47.6 65.7 27.0 15.7 2.6 21.8 20.3 8.0 25.9 20.2 36.6 11.1 26.5 32.2 0.1 0.0 41.5 29.7 28.5 25.1 0.0 0.3 0.0 1.1 0.2 0.6 0.2 0.9 1.6 0.5 0.5 0.2 0.8 0.0 1.0 0.1 0.1 1.8 0.2 20.1 25.8 25.3 25.1 16.0 18.6 28.8 25.8 31.9 20.8 25.6 37.0 6.1 3.2 14.0 64.6 6.4 3.8 34.4 6.5 5.7 14.8 5.5 6.5 26.2 18.6 15.2 5.5 16.7 0.1 30.0 47.7 21.5 10.9 29.4 11.9 11.6 5.6 22.8 5.7 159.9 23.1 0.1 9.2 28.1 18.9 0.0 5.8 2.9 0.4 3.5 20.2 142.9 17.3 14.2 6.7 6.7 16.2 10.2 6.7 17.8 64.6 5.5 28.9 12.3 153.3 359.4 36.0 20.1 11.3 9.5 74.8 14.5 7.9 17.5 30.0 6.6 7.7 18.2 25.4 8.1 7.5 4.4 0.3 19.4 15.8 22.4 50.6 STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 454.6;Erythroid cells: 535.1;Hepatocytes: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 591.3;hTCEpi: 497.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" 339.0 117.3 100.4 101.0 108.1 358.2 243.8 94.7 103.9 129.3 74.8 226.0 46.1 139.9 72.2 87.8 141.7 153.3 219.7 90.5 113.1 123.9 355.4 290.7 67.7 120.7 115.1 81.3 38.9 45.3 49.8 272.7 108.9 111.6 58.4 15.0 95.5 93.4 102.6 118.3 114.1 155.9 105.2 121.6 139.3 24.7 111.0 33.8 112.9 106.2 46.4 182.4 129.6 108.7 8.4 55.0 4.8 26.0 591.3 170.3 0.4 138.6 149.3 40.7 64.5 7.6 10.8 66.5 34.3 186.6 23.9 14.7 31.7 133.0 79.3 41.7 12.0 144.7 108.8 23.1 299.0 61.4 32.4 272.2 497.3 60.9 88.0 11.7 152.5 21.0 33.3 88.2 96.8 45.2 2.2 47.0 64.4 3.5 16.6 8.7 0.2 147.7 34.7 1.7 5.9 0.5 114.5 107.8 62.1 44.9 36.6 47.4 172.8 92.0 28.1 91.3 13.6 36.5 44.9 4.4 35.1 58.1 51.0 21.4 35.5 4.1 168.9 55.8 165.7 5.9 84.2 153.3 35.8 4.2 15.0 81.1 20.8 147.1 41.0 6.1 8.7 128.8 100.4 108.1 94.7 103.9 90.5 113.1 120.7 115.1 108.9 105.2 111.0 108.7 454.6 160.3 96.6 30.0 13.2 105.5 251.8 107.0 62.0 5.0 135.8 72.3 36.7 121.5 159.0 35.0 6.2 121.9 72.1 26.3 3.9 56.6 3.6 97.0 75.4 313.6 0.0 535.1 3.2 22.0 54.7 140.3 17.9 11.7 36.1 76.0 282.7 371.2 92.1 3.3 4.8 1.1 54.9 226.3 92.3 9.0 66.5 105.9 88.9 70.3 37.9 8.6 127.7 6.6 4.5 39.1 18.3 103.0 16.9 90.2 33.8 92.8 216.0 5.0 138.1 73.2 188.1 40.8 13.7 48.4 119.1 172.8 98.8 81.8 2.2 200.0 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 STOX1 "C10orf24, FLJ25162" ENSG00000165730 "Storkhead box 1" Q6ZVD7 10 68827531-68895432 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.2;choroid plexus: 30.8" "Group enriched" "Detected in many" 5 "Astrocytes: 85.2;Endometrial ciliated cells: 67.4;Respiratory ciliated cells: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 8.6;HAP1: 8.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037844, HPA037845" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Intracellular and membrane" No NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA037844: AB_2675700, HPA037845: AB_10671369" "prognostic favorable (3.37e-5)" "unprognostic (5.53e-3)" "unprognostic (6.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.63e-3)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "prognostic favorable (2.08e-4)" "unprognostic (1.52e-1)" "unprognostic (2.45e-3)" "unprognostic (5.33e-3)" "unprognostic (5.29e-2)" "unprognostic (3.87e-2)" "unprognostic (8.77e-2)" "unprognostic (3.06e-2)" "unprognostic (2.33e-1)" "unprognostic (3.46e-2)" 6.3 5.1 26.4 0.5 23.6 0.2 4.2 14.9 33.2 1.9 30.8 1.6 1.1 1.6 7.4 1.4 12.5 0.9 0.4 23.9 22.4 2.8 0.3 1.3 1.2 16.5 24.9 1.1 1.4 6.5 7.2 0.8 17.4 1.2 1.6 0.7 1.6 1.1 1.3 0.9 2.1 0.8 16.3 0.4 3.4 2.5 26.2 6.7 3.1 0.8 1.0 2.5 0.7 20.5 1.8 2.0 4.2 8.6 1.8 0.0 2.5 0.2 0.1 1.2 1.3 1.8 2.6 1.7 2.4 0.0 3.3 0.5 8.1 0.0 0.6 2.0 3.4 0.1 0.4 2.6 0.2 2.3 3.1 0.2 0.1 0.2 0.0 0.2 0.1 4.5 0.4 0.2 0.1 1.8 3.9 2.8 1.4 0.4 1.2 2.8 0.1 0.0 2.6 4.6 1.3 3.9 3.1 0.8 0.6 2.7 1.9 1.8 0.0 0.0 0.2 0.0 1.3 0.7 1.6 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.0 1.0 0.0 0.0 26.4 23.6 14.9 33.2 23.9 22.4 16.5 24.9 17.4 16.3 26.2 20.5 0.3 0.0 0.5 85.2 0.3 1.5 4.5 0.9 1.2 0.7 5.1 4.1 0.5 0.0 5.6 1.8 0.0 1.6 3.1 0.4 3.9 0.1 0.3 67.4 1.7 0.4 0.0 1.7 11.4 0.4 0.5 0.6 0.5 4.2 2.5 0.8 0.0 0.2 0.1 0.0 9.9 2.5 2.0 0.3 0.7 0.7 1.2 0.2 0.0 1.9 0.1 1.9 2.1 6.0 2.1 0.1 0.3 0.0 0.6 1.7 0.8 1.8 42.8 0.4 6.6 1.5 5.0 1.4 8.8 0.4 0.4 1.2 0.7 6.9 5.3 1.8 STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839266 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 152.2;Endometrial ciliated cells: 86.4;Late spermatids: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" 17.7 11.0 11.2 9.1 11.7 6.4 12.0 12.3 13.4 15.1 24.7 21.2 4.2 14.3 9.8 6.0 16.3 9.9 17.0 12.2 12.1 14.4 13.3 17.8 8.6 15.5 12.3 15.3 10.9 5.9 14.6 13.2 14.5 8.4 6.8 16.7 5.0 10.6 6.7 5.1 11.4 17.2 13.0 12.4 11.4 17.0 11.8 6.9 12.4 7.9 6.2 14.5 10.7 16.3 9.6 18.3 26.8 22.4 27.8 63.2 2.8 44.2 35.8 50.8 35.7 5.5 6.6 11.7 6.6 50.5 16.4 2.8 24.4 6.6 54.9 18.7 9.2 6.4 15.9 15.7 30.6 9.2 15.5 23.4 8.3 24.9 20.1 48.2 27.6 12.7 25.7 11.2 46.2 5.6 13.3 10.6 17.9 2.9 28.2 13.7 18.9 7.0 28.7 2.1 24.3 25.4 20.4 1.8 18.1 23.4 6.1 6.4 36.5 30.1 20.3 33.1 19.6 8.1 6.7 7.9 35.0 10.8 24.4 1.0 0.4 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.3 0.3 0.6 0.6 0.4 0.2 0.2 0.3 0.4 0.2 11.2 11.7 12.3 13.4 12.2 12.1 15.5 12.3 14.5 13.0 11.8 16.3 35.3 22.4 14.8 20.5 6.2 3.4 1.2 2.1 3.4 5.6 2.1 3.0 17.2 11.5 6.9 29.5 0.0 1.8 12.3 0.4 9.8 19.1 152.2 86.4 40.0 22.4 6.7 32.4 33.6 7.4 7.1 26.5 2.6 7.6 1.3 10.9 17.9 19.0 11.5 0.0 17.6 0.7 2.0 11.5 12.3 114.4 28.0 15.1 14.2 23.4 10.3 12.3 6.2 15.1 24.3 14.5 0.1 24.5 10.2 2.0 0.1 17.6 33.9 31.4 13.1 26.1 29.6 42.0 34.2 1.7 1.4 0.8 14.2 11.7 0.6 0.5 STXBP2 "Hunc18b, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636881-7647873 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 194.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 262.5;Macrophages: 249.1;monocytes: 368.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 248.6;classical monocyte: 471.0;eosinophil: 295.6;intermediate monocyte: 604.8;myeloid DC: 239.7;neutrophil: 356.2;non-classical monocyte: 893.3" "Group enriched" "Detected in all" 6 "dendritic cells: 239.7;granulocytes: 356.2;monocytes: 893.3" "Cell line enhanced" "Detected in many" "HMC-1: 244.8;U-937: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" 24.2 22.8 5.2 65.9 6.3 194.2 24.3 4.8 10.9 22.2 9.3 52.5 67.4 8.4 33.2 73.1 27.7 28.4 7.5 5.1 6.2 62.4 49.0 89.6 51.0 8.3 6.6 5.3 86.7 36.1 29.4 36.3 7.9 52.1 37.0 4.2 79.4 22.8 2.9 52.3 63.9 14.6 6.7 162.2 71.9 74.9 8.8 85.3 52.0 3.0 34.6 34.6 34.8 9.3 113.0 39.1 0.9 0.5 0.0 0.9 75.6 14.2 1.5 2.7 7.4 92.5 69.6 29.6 55.4 11.3 49.5 75.5 4.1 67.5 2.7 124.1 46.9 127.8 49.7 55.8 63.6 83.2 244.8 4.4 67.4 13.4 38.0 0.3 58.5 74.7 81.4 98.5 0.0 70.9 41.2 193.2 28.7 72.7 68.0 41.8 0.3 114.7 55.0 128.1 11.5 0.6 34.0 49.6 2.2 35.6 61.9 212.7 61.7 0.4 21.8 1.5 0.8 108.4 58.6 38.8 1.2 224.8 2.7 248.6 471.0 295.6 69.9 604.8 56.7 47.3 52.7 63.8 239.7 52.2 36.6 44.3 356.2 74.7 893.3 91.5 78.9 306.9 5.2 6.3 4.8 10.9 5.1 6.2 8.3 6.6 7.9 6.7 8.8 9.3 2.1 0.0 7.7 0.7 44.1 23.6 48.2 105.1 18.8 6.0 38.0 22.9 0.9 31.5 68.5 35.0 2.1 97.7 56.2 181.4 33.2 100.3 99.9 32.5 5.4 6.7 59.8 38.3 0.6 118.8 123.2 5.7 150.3 47.6 71.8 34.6 16.4 19.6 168.4 0.0 0.4 108.2 105.8 262.5 46.6 233.5 1.8 249.1 14.2 1.0 368.2 0.9 72.1 0.0 0.0 132.8 152.6 1.9 54.7 49.1 171.7 75.9 42.5 4.0 6.6 1.0 8.6 45.7 20.2 35.3 21.3 153.0 47.7 6.0 79.3 68.7 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SUCNR1 GPR91 ENSG00000198829 "Succinate receptor 1" Q9BXA5 3 151873643-151884619 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 39.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 19.6;Hofbauer cells: 22.0;Kupffer cells: 32.0;Macrophages: 11.8;Proximal tubular cells: 46.3;Smooth muscle cells: 11.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEL: 53.3;NB-4: 31.0;U-937: 52.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB022745 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB022745: " "unprognostic (1.54e-1)" "unprognostic (2.65e-2)" "unprognostic (3.45e-2)" "unprognostic (6.94e-2)" "unprognostic (1.58e-1)" "unprognostic (6.01e-2)" "unprognostic (3.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (8.92e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.14e-2)" "unprognostic (7.49e-2)" "unprognostic (1.58e-1)" 3.5 0.8 0.0 1.3 0.1 8.1 1.0 0.0 0.2 0.2 0.0 0.5 1.2 0.1 0.1 0.2 0.1 0.5 0.7 0.0 0.2 39.9 5.2 2.6 1.9 0.2 0.2 0.1 0.0 3.4 0.0 0.2 0.3 0.1 0.8 0.0 0.6 0.1 0.0 1.0 1.0 0.7 0.1 7.0 7.8 0.1 0.4 0.9 9.3 0.1 0.6 0.6 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 8.7 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.2 0.2 0.3 0.1 0.4 0.2 8.4 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.5 1.5 0.1 3.7 0.0 0.1 1.4 0.0 19.6 0.0 0.5 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 4.3 22.0 0.0 0.0 0.2 8.2 32.0 8.1 0.4 0.0 11.8 0.0 8.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 46.3 1.5 0.0 0.0 0.1 11.2 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.1 SUMO3 "SMT3A, SMT3H1" ENSG00000184900 "Small ubiquitin like modifier 3" P55854 21 44805617-44818779 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012180, HPA042123, HPA048064" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nuclear bodies" "CAB012180: AB_304041, HPA042123: AB_2677860, HPA048064: AB_2680244" "unprognostic (2.77e-2)" "unprognostic (2.52e-1)" "unprognostic (5.79e-2)" "prognostic unfavorable (7.88e-5)" "unprognostic (1.96e-1)" "unprognostic (1.21e-1)" "unprognostic (6.81e-2)" "unprognostic (7.13e-2)" "unprognostic (1.43e-1)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (7.15e-2)" "unprognostic (1.09e-2)" "unprognostic (3.00e-2)" "unprognostic (1.62e-1)" "unprognostic (7.50e-2)" "unprognostic (1.80e-2)" 68.6 58.1 58.5 56.7 64.6 118.8 63.6 50.6 75.5 55.5 55.9 55.2 55.1 52.9 50.3 57.2 52.1 44.6 74.3 64.4 71.8 64.0 59.3 61.7 68.8 53.3 59.0 57.6 49.4 44.7 38.3 49.1 58.3 46.2 45.8 72.0 66.5 47.4 106.6 51.0 58.0 39.8 54.5 61.6 56.3 28.8 68.5 63.7 54.8 73.9 57.5 50.0 53.6 50.9 226.4 88.8 131.7 80.2 105.1 147.9 86.5 152.0 177.2 211.5 173.6 133.6 137.2 78.4 234.6 165.4 122.4 53.0 96.8 123.0 166.3 110.0 106.3 322.7 78.8 123.1 113.3 184.5 172.1 126.0 139.5 123.9 89.9 87.8 109.8 164.6 188.7 215.2 173.8 293.1 220.0 127.7 254.4 223.1 174.9 239.0 8.0 217.1 120.2 111.9 98.8 153.4 136.5 196.2 126.3 48.1 190.6 218.6 172.4 99.1 151.4 151.6 172.8 155.4 234.8 198.7 77.9 265.2 138.6 2.8 123.1 52.0 78.9 130.0 79.7 84.6 74.9 76.5 133.3 77.7 88.7 81.0 14.0 70.6 122.3 162.8 91.2 157.8 58.5 64.6 50.6 75.5 64.4 71.8 53.3 59.0 58.3 54.5 68.5 50.9 83.4 64.1 50.4 5.5 76.5 96.0 121.7 127.9 74.6 72.2 99.4 88.5 59.5 67.2 66.5 95.6 20.9 122.9 98.1 95.6 166.3 121.7 63.1 36.4 51.7 101.4 59.2 113.8 14.3 112.4 107.8 76.7 52.0 37.9 29.8 63.8 92.8 116.6 200.5 62.2 13.3 91.5 81.4 143.4 172.3 114.2 72.1 137.9 97.8 10.3 280.0 132.4 111.2 3.5 6.5 148.7 112.6 72.6 58.2 150.7 129.2 130.2 33.0 60.5 59.2 43.8 68.7 90.7 77.5 82.7 77.9 136.3 78.2 43.2 99.9 145.1 SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" 97.0 106.4 20.3 38.8 22.5 66.5 76.5 22.1 23.4 70.5 27.9 72.1 79.2 78.5 40.6 77.6 71.1 39.0 74.1 21.5 22.3 67.1 223.8 84.2 29.6 23.6 22.2 61.0 150.4 35.4 88.6 55.4 22.2 69.2 37.9 14.0 86.4 39.5 60.1 63.2 82.2 43.4 22.9 59.6 88.5 49.4 25.8 27.8 68.2 23.3 31.4 62.7 59.4 25.9 59.8 96.4 65.3 90.3 134.8 140.2 127.4 184.1 178.4 127.0 124.7 145.9 84.8 41.1 70.6 254.2 122.9 152.7 75.7 94.4 97.0 86.5 46.3 72.1 87.1 156.5 156.2 124.8 94.1 150.4 85.8 109.3 120.2 101.6 118.6 62.9 89.0 109.8 164.5 131.8 60.1 115.4 72.7 162.8 96.2 41.2 89.9 156.5 100.4 56.3 53.8 65.5 136.4 100.4 95.2 61.5 106.6 75.8 127.5 179.4 64.5 137.3 119.6 56.1 86.4 46.4 166.7 66.6 137.5 43.9 40.8 36.2 51.9 32.8 56.9 15.1 36.3 48.4 32.9 12.1 22.0 34.6 28.4 29.4 31.7 38.9 46.9 68.8 20.3 22.5 22.1 23.4 21.5 22.3 23.6 22.2 22.2 22.9 25.8 25.9 53.5 44.8 48.1 18.9 43.0 60.8 65.8 72.5 46.1 21.9 55.5 43.2 42.6 31.5 47.5 35.0 39.6 167.9 80.4 106.9 19.6 95.7 38.6 28.6 72.8 54.8 75.2 31.1 23.2 118.1 254.4 84.8 78.5 67.7 24.7 49.5 47.5 207.3 85.9 33.7 15.6 107.9 30.5 52.3 50.5 19.7 68.3 50.8 40.9 17.8 53.7 53.3 52.5 22.6 23.8 115.1 65.5 53.0 114.8 106.8 151.3 48.5 23.2 26.9 78.9 51.9 80.6 84.4 47.3 46.1 62.4 325.2 90.5 81.8 81.2 84.2 SUSD3 MGC26847 ENSG00000157303 "Sushi domain containing 3" Q96L08 9 93058688-93085133 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.3;testis: 77.2" "Cell type enhanced" "Detected in many" "B-cells: 32.4;Granulosa cells: 30.8;Hepatocytes: 66.6;Hofbauer cells: 49.4;Proximal tubular cells: 59.4;T-cells: 37.5;Theca cells: 34.7" "Cancer enhanced" "Detected in all" "breast cancer: 50.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 150.7;Karpas-707: 32.6;MCF7: 36.8;NB-4: 78.0;RPMI-8226: 82.5;THP-1: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042310 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "HPA042310: AB_10796902" "prognostic favorable (5.13e-4)" "unprognostic (5.42e-2)" "unprognostic (3.65e-1)" "unprognostic (8.34e-3)" "unprognostic (9.06e-2)" "unprognostic (2.84e-2)" "unprognostic (2.94e-2)" "unprognostic (7.41e-3)" "unprognostic (5.06e-2)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (3.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.39e-3)" "unprognostic (5.33e-2)" 6.1 1.8 4.5 17.6 3.9 41.3 15.4 4.6 4.3 16.7 4.4 3.8 4.9 19.8 10.0 4.2 35.4 4.2 1.3 4.3 5.6 21.2 27.8 4.1 57.3 6.4 5.7 40.1 1.0 1.3 5.4 2.0 6.5 2.4 2.2 6.4 11.4 3.2 1.2 3.6 18.7 6.1 6.6 36.3 4.5 77.2 5.9 31.8 4.2 0.6 30.5 4.4 6.1 8.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.8 1.5 0.6 0.3 3.4 1.3 150.7 0.6 0.6 0.1 0.3 2.4 0.1 0.0 13.4 0.1 20.7 0.1 2.4 9.5 0.1 4.6 9.9 0.7 0.0 0.0 0.0 0.0 0.0 6.2 32.6 0.0 36.8 0.2 78.0 1.8 1.1 4.6 6.5 0.0 82.5 0.0 0.0 0.2 0.2 0.1 1.1 0.0 1.7 19.4 34.6 0.5 0.0 0.0 0.0 0.0 6.6 3.8 9.7 0.0 0.0 0.2 0.6 16.7 79.1 24.0 15.5 27.4 88.7 124.8 43.4 41.1 70.1 214.8 87.7 5.8 11.2 3.0 3.6 182.9 68.3 4.5 3.9 4.6 4.3 4.3 5.6 6.4 5.7 6.5 6.6 5.9 8.0 2.6 0.0 6.7 0.0 32.4 0.6 0.2 0.3 0.0 0.5 24.2 11.0 0.8 17.2 0.2 0.0 4.2 1.0 2.4 0.4 9.8 0.7 3.0 0.4 2.9 3.4 0.0 2.5 0.1 0.2 2.1 9.0 1.1 0.3 3.8 30.8 1.4 66.6 49.4 0.0 0.1 0.4 8.2 10.5 9.2 11.2 5.6 29.1 1.8 17.8 8.3 1.7 2.1 0.5 0.1 0.6 0.1 5.3 17.9 1.4 0.2 59.4 0.7 9.2 0.0 0.1 1.6 3.4 3.9 0.1 0.3 1.4 37.5 34.7 0.7 0.2 SV2B "HsT19680, KIAA0735" ENSG00000185518 "Synaptic vesicle glycoprotein 2B" Q7L1I2 15 91099950-91302565 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 34.5;retina: 56.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 137.1;Cone photoreceptor cells: 150.1;Excitatory neurons: 455.0;Rod photoreceptor cells: 139.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 2.1;SCLC-21H: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046247 Approved NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046247: AB_10963538" "unprognostic (2.92e-1)" "unprognostic (7.92e-2)" "unprognostic (1.32e-3)" "unprognostic (4.01e-5)" "unprognostic (2.66e-3)" "unprognostic (7.77e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (9.89e-2)" "unprognostic (1.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.39e-1)" "unprognostic (3.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-2)" "unprognostic (3.10e-4)" 1.8 1.1 17.2 0.2 17.5 0.1 0.8 7.3 34.5 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.2 0.8 22.4 0.0 0.3 0.1 0.2 0.4 8.5 0.0 0.0 1.4 0.1 1.0 0.2 10.7 0.8 0.3 56.3 1.0 0.1 0.6 0.2 0.4 0.2 0.0 0.2 0.3 0.8 1.4 0.6 0.2 1.0 1.2 0.1 0.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.2 17.5 7.3 34.5 22.4 0.0 8.5 0.0 10.7 0.0 1.4 14.8 10.9 0.0 0.0 7.2 0.1 0.4 0.1 0.1 0.0 137.1 0.2 0.5 3.0 1.5 0.0 0.0 150.1 0.0 0.0 0.0 0.0 4.2 6.4 0.0 0.0 3.3 0.0 0.0 455.0 5.0 0.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.1 3.3 11.4 0.0 0.0 0.0 0.4 2.0 0.0 0.2 0.0 27.2 0.0 43.4 0.0 5.5 39.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 139.0 0.0 0.5 0.2 8.0 0.4 0.1 0.1 0.0 0.1 0.1 0.0 0.2 SYN2 "SYNII, SYNIIa, SYNIIb" ENSG00000157152 "Synapsin II" Q92777 3 12004388-12192032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Schizophrenia "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 96.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 338.3;Inhibitory neurons: 543.3;Oligodendrocyte precursor cells: 128.2" "Cancer enhanced" "Detected in many" "glioma: 4.5" "Group enriched" "Detected in many" 5 "amygdala: 67.0;basal ganglia: 77.7;cerebral cortex: 96.8;hippocampal formation: 92.9;white matter: 44.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HMC-1: 4.5;NTERA-2: 3.3;SCLC-21H: 2.7;SH-SY5Y: 11.1;SuSa: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037012, CAB079005" Supported Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB079005: , HPA037012: AB_2675431" "unprognostic (1.62e-3)" "unprognostic (1.60e-2)" "unprognostic (7.54e-2)" "unprognostic (9.87e-3)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (6.32e-3)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (9.77e-2)" "unprognostic (4.89e-4)" "unprognostic (9.94e-2)" "unprognostic (7.35e-2)" "unprognostic (1.78e-2)" 7.0 3.1 67.0 0.4 77.7 0.1 7.1 3.8 96.8 1.4 0.0 2.3 0.4 2.0 1.0 0.3 1.2 0.4 1.0 92.9 2.9 1.5 0.0 1.1 0.0 13.4 0.0 1.5 0.5 4.1 3.4 2.8 10.8 0.5 0.5 7.8 2.4 0.2 0.9 2.5 1.6 1.8 0.0 0.6 1.8 3.6 15.3 0.1 0.2 0.4 0.0 0.3 1.3 44.9 0.0 0.2 0.0 0.0 1.8 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.2 1.0 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.1 0.2 0.0 0.0 0.0 0.0 0.2 2.7 11.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.0 77.7 3.8 96.8 92.9 2.9 13.4 0.0 10.8 0.0 15.3 44.9 43.4 0.0 0.0 7.8 0.0 0.0 0.4 0.0 0.6 13.9 0.4 2.4 1.4 0.0 0.0 0.0 6.2 1.7 0.1 0.0 0.0 0.0 0.6 0.2 0.1 4.5 0.0 0.0 338.3 0.0 0.4 0.9 0.0 0.3 0.0 0.2 0.7 0.0 0.6 13.5 543.3 0.0 0.0 1.8 0.0 1.8 0.0 0.3 0.0 4.7 0.1 2.5 0.0 128.2 8.3 0.3 0.0 0.0 0.0 0.3 0.0 2.7 0.0 3.7 0.0 0.7 0.7 4.9 6.9 0.0 0.0 0.8 0.1 0.1 0.0 0.2 SYNE3 "C14orf139, C14orf49, FLJ25605, LINC00341, NCRNA00341, Nesp3, Nesprin-3, NET53" ENSG00000176438 "Spectrin repeat containing nuclear envelope family member 3" Q6ZMZ3 14 95407266-95475836 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 70.2;Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 103.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 46.5;ASC TERT1: 36.2;Karpas-707: 42.3;REH: 34.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055227, HPA077140" Approved Supported "Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear membrane" "HPA055227: AB_2682747, HPA077140: AB_2686826" "unprognostic (4.63e-2)" "unprognostic (6.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.48e-3)" "unprognostic (7.15e-2)" "unprognostic (2.12e-3)" "unprognostic (2.45e-1)" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.87e-1)" "unprognostic (8.50e-2)" "unprognostic (3.32e-1)" "unprognostic (7.41e-6)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.19e-2)" 19.1 3.4 5.1 4.3 9.5 13.7 12.6 5.8 6.7 4.0 8.7 2.8 1.5 2.3 1.4 2.0 4.5 2.1 4.3 4.5 5.5 1.1 3.0 4.4 6.0 10.0 8.0 4.0 0.9 0.4 1.7 3.4 7.4 1.6 2.6 11.9 3.2 1.1 2.2 4.3 3.8 2.2 5.6 5.0 2.1 2.7 8.3 2.4 2.9 3.3 6.0 3.2 4.1 12.3 1.2 0.1 0.7 1.1 46.5 36.2 14.3 5.4 9.4 5.1 4.0 7.8 1.3 6.3 0.9 2.6 1.6 0.3 1.1 4.0 2.3 20.9 0.9 4.3 0.9 2.1 6.0 6.6 10.4 10.2 1.4 6.4 3.7 0.4 9.0 1.9 0.3 42.3 3.9 1.5 3.9 7.3 0.1 0.2 2.6 34.8 23.2 13.5 0.6 0.7 1.0 5.1 0.2 0.1 2.5 0.6 2.0 9.6 8.2 3.7 2.2 5.0 0.7 5.0 11.1 5.9 7.4 14.6 28.2 2.2 1.9 0.1 0.7 1.5 0.9 1.2 1.0 0.8 0.8 1.0 1.2 1.0 0.9 0.3 1.6 1.0 0.9 1.0 5.1 9.5 5.8 6.7 4.5 5.5 10.0 8.0 7.4 5.6 8.3 12.3 12.4 9.6 18.3 3.3 19.7 2.3 0.4 0.1 0.6 5.1 1.0 1.3 70.2 0.0 0.7 0.0 62.6 2.2 16.1 4.9 0.0 0.0 3.9 6.5 5.1 14.7 1.2 4.0 2.5 0.4 15.0 22.3 1.1 1.4 12.0 0.2 5.0 6.8 4.3 6.7 3.3 5.0 0.0 17.6 14.8 2.4 13.1 20.3 5.4 3.7 27.8 5.3 9.2 14.1 20.8 0.5 6.2 0.4 20.6 1.9 2.9 0.4 6.6 103.7 6.6 19.1 12.1 0.6 1.1 0.3 1.0 1.9 14.0 0.0 1.9 0.5 SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 434.8;monocytes: 836.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 672.3;OE19: 547.9;SK-BR-3: 630.6;T-47d: 502.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "HPA014742: AB_2669079" "unprognostic (2.19e-2)" "unprognostic (1.05e-3)" "unprognostic (2.84e-1)" "unprognostic (6.77e-3)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-3)" "unprognostic (4.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-2)" "unprognostic (9.44e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (4.74e-2)" "unprognostic (5.21e-2)" "unprognostic (3.51e-2)" "unprognostic (1.78e-2)" 92.9 59.7 50.9 99.4 74.0 112.9 105.5 75.1 63.5 59.2 53.5 118.0 86.4 56.7 22.6 133.8 75.5 70.7 150.1 51.5 61.2 113.0 101.0 158.1 143.9 88.1 70.7 45.3 188.9 52.9 91.2 61.7 86.0 130.7 71.1 2.8 184.8 45.6 369.9 161.4 125.4 33.2 67.3 148.1 141.7 31.8 68.0 68.2 68.7 122.6 112.6 92.0 87.9 92.5 172.5 334.5 9.0 73.9 3.2 1.1 52.5 58.6 60.2 55.0 31.4 200.9 173.6 136.9 123.2 33.5 47.8 245.5 39.9 95.0 16.2 97.2 177.2 47.0 46.9 140.8 76.1 77.3 356.5 3.4 105.1 17.5 47.2 77.9 118.7 50.4 193.9 672.3 5.3 337.4 77.3 79.6 24.4 547.9 140.1 44.3 19.2 391.4 166.7 155.5 53.8 60.2 48.6 630.6 60.3 31.7 502.8 122.2 31.7 1.1 54.2 28.1 77.8 280.7 109.7 79.8 39.7 52.8 9.5 694.4 656.1 237.9 173.6 944.7 202.1 970.0 231.0 200.2 907.6 972.1 204.6 168.6 282.5 219.8 1139.9 530.1 314.6 837.0 50.9 74.0 75.1 63.5 51.5 61.2 88.1 70.7 86.0 67.3 68.0 92.5 56.1 128.2 113.4 3.3 226.6 124.1 136.1 170.9 79.1 3.3 126.5 84.1 63.0 68.6 153.2 171.0 6.2 169.7 63.1 125.2 9.8 313.6 3.6 41.2 9.6 83.5 72.6 70.2 2.4 434.8 59.1 27.9 104.5 89.7 103.0 25.3 56.4 46.9 255.5 5.0 1.2 327.6 193.3 137.9 330.6 4.9 22.1 150.3 74.7 16.9 836.7 5.1 24.7 2.5 31.3 286.5 160.9 17.0 159.2 282.4 77.5 36.2 63.4 3.9 39.5 26.0 46.2 13.4 12.3 120.1 163.4 179.5 58.8 11.4 212.8 216.8 SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 594.1;skeletal muscle: 624.7;urinary bladder: 406.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 103.5;Cardiomyocytes: 502.5;Muller glia cells: 127.8;Smooth muscle cells: 98.5" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.8;HeLa: 58.0;WM-115: 124.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB017192: , HPA040066: AB_2676830, HPA044200: AB_2678854, HPA077856: AB_2686861" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-2)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-2)" "unprognostic (6.75e-2)" "unprognostic (3.54e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-2)" "unprognostic (5.92e-3)" "unprognostic (3.26e-3)" 37.2 20.3 51.4 26.5 66.0 0.4 56.7 70.1 58.2 11.8 52.5 594.1 27.1 50.8 12.7 169.6 36.5 19.2 144.2 44.4 75.4 6.9 4.8 23.1 4.2 81.7 66.6 14.1 6.3 8.2 23.2 14.0 81.6 150.6 52.0 40.3 25.6 291.3 624.7 17.0 105.7 160.9 71.6 2.9 158.4 5.2 69.3 3.7 11.2 277.1 4.0 406.3 41.0 79.8 6.6 36.8 8.1 21.9 15.9 0.9 0.5 3.7 5.3 2.1 1.3 5.4 4.9 0.0 5.3 5.3 17.7 4.2 5.5 0.1 1.6 0.5 9.0 0.1 58.0 5.4 9.0 0.0 1.0 0.9 0.3 3.7 0.8 6.0 4.3 0.0 0.2 7.4 5.5 3.7 0.7 0.8 7.2 0.7 11.4 0.0 7.5 5.5 2.1 3.6 3.6 4.2 21.9 3.4 13.5 12.7 0.2 3.6 4.8 4.1 0.4 2.9 8.9 0.1 1.0 0.0 0.4 0.0 124.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 51.4 66.0 70.1 58.2 44.4 75.4 81.7 66.6 81.6 71.6 69.3 79.8 14.8 0.0 1.7 15.3 0.9 2.3 0.7 0.9 2.8 12.6 32.7 103.5 502.5 0.0 1.2 0.0 16.7 1.5 6.6 2.1 0.0 0.5 9.5 1.3 1.0 24.2 3.0 0.0 15.6 1.3 0.7 20.3 5.1 4.2 0.0 1.1 3.6 1.3 0.3 42.1 9.8 0.9 0.0 0.0 5.1 4.5 1.2 2.0 5.4 12.2 0.6 127.8 1.0 2.5 14.0 0.2 2.3 4.1 5.4 2.0 0.6 0.3 3.1 10.2 32.9 19.6 98.5 7.9 11.5 2.1 3.7 0.4 5.9 0.2 0.7 0.9 SYTL5 ENSG00000147041 "Synaptotagmin like 5" Q8TDW5 X 38006553-38128819 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.6;stomach 1: 12.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 37.2;Inhibitory neurons: 92.0;Intestinal goblet cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.2;MCF7: 5.8;OE19: 8.4;SK-MEL-30: 14.8;SuSa: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA026074 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Microtubules, Cytosol" "HPA026074: AB_1857697" "unprognostic (3.60e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (6.68e-2)" "unprognostic (3.09e-3)" "unprognostic (3.22e-2)" "unprognostic (2.01e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.10e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (5.21e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" 0.0 8.2 6.5 0.3 7.2 0.0 2.5 0.0 5.6 5.6 0.1 2.8 2.2 2.2 0.8 3.1 0.4 0.5 1.1 6.7 10.7 1.2 4.4 0.6 0.0 3.4 13.6 0.1 5.8 0.0 0.6 7.4 6.3 0.9 3.2 0.5 2.2 0.4 0.0 0.1 2.4 3.3 2.5 0.0 12.1 0.6 8.6 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 1.2 0.2 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 6.2 1.4 0.0 0.0 0.5 2.2 0.7 0.0 0.0 0.0 0.0 0.6 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.7 0.1 0.0 0.1 0.2 0.2 5.8 0.0 0.0 2.5 8.4 0.0 0.0 2.0 0.0 0.0 0.4 3.2 0.0 0.3 1.2 14.8 19.5 0.0 0.0 0.0 0.1 4.7 0.0 3.3 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 7.2 0.0 5.6 6.7 10.7 3.4 13.6 6.3 2.5 8.6 0.9 0.0 0.0 2.0 1.6 0.0 0.0 0.2 0.8 0.0 0.0 4.0 1.5 0.3 0.0 8.7 0.0 0.0 3.3 0.0 4.6 0.0 0.0 0.0 0.7 3.6 0.1 3.0 0.0 1.4 0.9 3.6 0.6 37.2 4.0 0.0 1.0 0.4 1.3 0.3 0.0 92.0 20.8 6.1 0.0 0.0 0.0 0.6 0.2 0.0 1.0 0.2 0.0 0.0 0.0 1.1 4.9 3.0 2.6 0.3 0.6 0.6 0.1 3.3 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 8.9 0.1 0.0 0.7 1.0 TADA2B MGC21874 ENSG00000173011 "Transcriptional adaptor 2B" Q86TJ2 4 7041899-7057952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 40.4;Rod photoreceptor cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035770 Approved Approved "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA035770: AB_10603993" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "unprognostic (6.61e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (2.99e-1)" "unprognostic (6.03e-2)" "unprognostic (8.91e-3)" "unprognostic (1.72e-1)" "prognostic favorable (7.17e-11)" "unprognostic (5.00e-2)" "unprognostic (1.58e-1)" "unprognostic (2.59e-2)" "prognostic favorable (1.59e-4)" 10.9 16.3 7.7 13.1 8.1 35.4 10.5 9.3 10.4 10.6 8.3 12.7 13.4 11.8 8.1 14.6 12.2 10.2 20.6 11.0 6.5 12.3 15.7 11.7 17.8 8.7 7.0 19.3 30.2 16.7 9.1 10.8 8.6 12.8 10.3 20.2 24.4 13.0 52.0 12.1 13.0 11.6 6.4 15.3 14.6 15.5 8.2 12.0 16.4 42.4 12.6 11.5 9.2 8.3 11.5 17.2 11.8 14.0 12.8 14.5 11.3 16.5 16.9 20.9 12.8 17.0 16.8 15.2 9.6 18.4 27.8 9.2 16.3 8.7 13.4 9.0 12.5 15.5 10.5 12.9 15.6 17.9 24.3 10.5 18.2 13.9 16.1 14.4 9.8 13.9 17.6 23.9 15.8 11.0 21.8 15.3 14.0 15.3 26.4 14.0 24.1 8.0 19.1 15.9 19.2 13.8 14.2 12.6 16.6 9.5 19.0 26.6 15.3 13.2 10.2 16.1 22.9 21.6 19.5 19.7 10.9 9.7 13.7 0.7 1.3 6.9 2.7 1.7 1.9 2.5 1.7 2.6 1.2 1.7 2.3 1.7 4.4 1.5 2.1 1.3 2.0 1.2 7.7 8.1 9.3 10.4 11.0 6.5 8.7 7.0 8.6 6.4 8.2 8.3 7.1 9.6 15.0 7.2 9.0 4.6 2.7 3.3 0.6 27.1 12.4 8.0 12.7 4.3 9.1 7.3 31.3 3.6 14.2 10.6 5.9 4.5 2.9 8.6 9.0 6.4 7.2 2.1 5.0 9.3 2.9 8.0 8.2 8.7 9.5 6.3 4.2 16.7 5.7 40.4 5.2 9.5 4.1 8.8 4.2 4.8 16.8 7.0 7.2 1.9 8.1 10.4 6.2 5.0 3.7 7.9 7.8 12.8 5.1 5.8 8.7 7.6 7.1 38.3 0.0 12.4 5.2 6.1 4.5 3.6 5.8 4.4 10.1 12.5 6.9 5.4 TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "B-cells: 249.5;dendritic cells: 152.3;Macrophages: 91.1;NK-cells: 86.5;Plasma cells: 272.1;T-cells: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.1;HMC-1: 42.5;Karpas-707: 43.8;U-266/84: 20.6;U-698: 39.6;U-937: 33.4" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA031000: AB_10610560, HPA039982: " "unprognostic (9.86e-3)" "unprognostic (7.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.10e-3)" "unprognostic (1.04e-1)" "unprognostic (5.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.39e-2)" "unprognostic (6.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (7.39e-2)" 5.0 2.8 1.0 28.9 1.1 146.6 3.9 1.3 2.1 3.4 3.0 5.9 4.4 9.5 2.3 4.1 2.0 6.9 1.6 1.2 3.4 1.3 4.1 8.4 39.6 2.7 2.0 2.2 0.9 0.7 0.8 3.4 2.1 2.8 8.2 1.5 3.0 1.8 0.7 1.2 10.2 26.0 2.2 22.8 7.2 1.6 2.2 24.3 1.6 2.3 47.6 10.0 1.2 4.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 30.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 6.2 0.0 0.0 0.0 15.6 42.5 0.3 0.0 0.0 0.0 0.0 0.0 9.0 0.1 43.8 0.0 0.0 4.0 8.2 12.0 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.3 0.2 0.0 0.1 0.1 1.2 0.0 6.9 0.2 0.0 0.0 0.0 0.0 4.7 20.6 39.6 0.0 33.4 0.0 163.6 27.8 88.4 54.8 20.4 62.6 45.9 73.9 64.6 27.9 46.6 56.9 40.8 169.7 45.6 27.6 9.3 57.5 60.9 1.0 1.1 1.3 2.1 1.2 3.4 2.7 2.0 2.1 2.2 2.2 4.2 5.2 3.2 6.6 0.0 249.5 2.8 0.3 0.2 3.4 0.3 4.4 6.0 0.6 0.0 1.4 0.0 0.0 0.7 152.3 0.2 0.0 0.1 0.3 0.5 0.4 5.2 0.0 8.8 1.2 0.0 0.6 4.3 16.8 0.5 19.0 1.8 1.4 0.8 24.9 0.0 1.0 0.0 0.0 21.9 60.2 1.1 1.2 91.1 28.4 20.6 21.5 0.4 86.5 1.5 0.0 0.0 0.0 22.6 272.1 0.3 0.0 0.3 1.2 0.2 0.0 0.8 2.0 0.1 0.1 2.0 2.7 0.8 223.6 4.6 0.4 0.3 TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 9628.1;intestine: 11712.2" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 2508.6;Peritubular cells: 2306.4;Sertoli cells: 2866.2;Smooth muscle cells: 4563.9" "Cancer enhanced" "Detected in all" "prostate cancer: 279.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 41.6;non-classical monocyte: 63.1" "Lineage enriched" "Detected in many" 12 "monocytes: 63.1" "Cell line enhanced" "Detected in all" "BJ: 1913.4;BJ hTERT+ SV40 Large T+: 1641.8;CACO-2: 1531.4;EFO-21: 2145.6;fHDF/TERT166: 2094.4;hTERT-RPE1: 1499.7;LHCN-M2: 1377.1;U-138 MG: 1598.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467" Enhanced Approved Microtubules,Mitochondria,Cytosol No No 6300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Mitochondria" Cytosol "CAB001447: AB_564012, HPA019467: AB_1857245" "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-1)" "unprognostic (6.58e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (9.58e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-3)" 2235.7 512.7 118.5 963.9 144.4 12.1 1680.5 126.1 215.9 3611.3 172.5 11712.2 451.2 9628.1 693.9 1954.6 4610.6 893.8 1583.5 119.6 120.4 774.5 302.8 1258.6 245.5 137.0 127.0 1643.4 218.6 65.3 254.6 348.0 129.2 4624.1 1154.6 22.9 461.8 6383.6 356.4 619.8 1948.4 7108.7 127.2 532.0 3148.4 202.5 138.2 52.2 723.2 152.4 59.9 5521.7 2331.2 130.0 17.5 5.5 293.3 8.2 140.0 123.8 226.7 1913.4 788.1 1641.8 609.0 1531.4 28.4 3.2 2145.6 2094.4 1.7 46.1 4.4 16.8 543.3 6.8 4.4 5.0 66.9 130.2 708.7 1.7 5.2 304.6 57.5 267.1 36.1 1499.7 3.3 4.5 3.3 6.7 1377.1 4.5 1.7 15.8 84.6 18.8 2.1 2.7 23.1 12.0 4.4 25.8 1.9 9.6 29.9 11.0 1.5 807.6 9.2 5.1 182.0 1598.8 276.9 14.4 86.6 8.9 8.8 21.7 9.1 7.7 6.2 1.8 2.7 0.1 0.3 41.6 0.5 3.6 0.1 0.0 3.2 5.1 0.2 0.1 0.3 0.0 63.1 1.6 0.5 2.1 118.5 144.4 126.1 215.9 119.6 120.4 137.0 127.0 129.2 127.2 138.2 130.0 264.8 38.5 6.1 4.6 10.3 63.9 453.4 248.6 10.8 9.9 74.0 2508.6 1.3 4.3 22.5 40.5 18.8 57.0 8.6 3.1 0.0 577.8 3.3 14.6 455.5 260.3 3.0 2.7 4.5 74.5 35.3 464.4 41.3 12.8 1.3 32.4 639.7 8.9 41.5 1.7 6.5 18.3 24.4 23.1 91.8 23.9 48.4 33.8 96.0 37.5 8.1 4.9 2.1 3.0 11.9 38.4 4.5 2306.4 3.2 414.0 12.1 2.2 23.0 9.9 2866.2 177.6 4563.9 6.0 13.7 8.6 60.9 32.2 15.1 8.3 3.1 62.0 TALDO1 ENSG00000177156 "Transaldolase 1" P37837 11 747415-765012 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pentose shunt" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 820.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 2870.4;neutrophil: 3726.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048089 Approved Nucleoplasm,Cytosol NA NA 29000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "HPA048089: AB_2680260" "unprognostic (5.29e-2)" "unprognostic (1.78e-2)" "unprognostic (3.47e-1)" "unprognostic (9.65e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (9.78e-2)" "unprognostic (4.27e-2)" "unprognostic (1.74e-1)" "unprognostic (7.97e-3)" "unprognostic (2.94e-1)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (2.37e-1)" "unprognostic (1.16e-3)" 139.5 80.7 108.0 121.8 128.8 464.8 121.0 129.3 119.3 101.9 105.2 99.6 116.0 68.4 66.4 330.6 79.1 100.0 95.5 108.0 113.8 111.6 136.2 109.1 107.8 135.8 119.3 77.0 107.5 49.3 53.0 88.0 130.0 91.9 78.4 34.2 132.8 60.1 120.7 132.7 101.0 60.8 124.0 152.6 132.5 40.4 120.1 109.9 140.3 107.1 115.8 160.8 142.1 148.2 331.0 405.5 115.4 218.1 235.8 136.5 338.0 242.2 313.8 238.2 194.5 176.6 694.8 179.5 323.1 324.7 181.9 345.5 185.6 263.5 122.8 238.9 372.5 310.9 146.0 616.4 250.3 498.4 449.0 112.0 210.6 159.6 129.0 170.4 331.6 224.0 413.5 294.3 224.5 318.0 296.4 601.2 183.9 478.9 326.0 243.5 131.5 656.4 437.9 185.4 284.2 100.1 224.9 466.1 243.3 102.4 220.0 383.9 434.1 107.9 99.5 86.0 232.9 122.9 132.1 223.5 238.5 440.5 444.7 1456.7 1203.5 2870.4 94.1 432.7 102.3 145.5 125.7 115.5 654.2 127.2 100.9 94.9 3726.6 112.2 457.8 267.0 192.7 1066.0 108.0 128.8 129.3 119.3 108.0 113.8 135.8 119.3 130.0 124.0 120.1 148.2 90.2 141.1 117.2 10.7 91.1 73.5 199.8 354.0 61.5 50.3 113.0 122.2 46.4 100.1 253.4 150.8 14.6 419.8 83.8 151.0 250.5 230.4 82.1 156.5 85.4 85.6 101.5 507.0 13.1 272.1 427.6 97.3 144.3 216.7 161.4 86.0 93.5 149.7 418.3 50.5 11.6 186.0 268.5 271.8 169.4 21.2 117.8 352.8 140.5 7.5 820.0 142.1 84.5 10.6 54.8 257.6 200.3 104.2 129.4 361.9 197.7 309.1 232.6 61.7 72.3 59.6 115.0 143.2 140.6 257.6 83.1 526.6 86.8 77.5 215.1 342.6 TAMALIN GRASP ENSG00000161835 "Trafficking regulator and scaffold protein tamalin" Q7Z6J2 12 52006946-52015889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 243.8;B-cells: 60.6;dendritic cells: 114.1;Macrophages: 60.6;Plasma cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 37.4;TIME: 27.4;WM-115: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040664, HPA062028" Approved Approved "Nuclear bodies,Vesicles" No NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "Nuclear bodies" "HPA040664: AB_10794066, HPA062028: AB_2684664" "unprognostic (1.90e-1)" "unprognostic (1.29e-2)" "unprognostic (2.48e-2)" "unprognostic (2.39e-2)" "unprognostic (2.00e-2)" "unprognostic (2.38e-2)" "unprognostic (2.23e-2)" "unprognostic (1.93e-1)" "unprognostic (2.86e-1)" "unprognostic (8.71e-2)" "unprognostic (3.16e-3)" "unprognostic (7.20e-2)" "unprognostic (3.90e-3)" "unprognostic (1.99e-3)" "unprognostic (1.44e-1)" "unprognostic (3.53e-2)" "unprognostic (2.77e-2)" 31.9 6.3 9.8 4.1 14.9 23.8 26.9 3.2 21.5 17.6 0.4 9.4 2.2 22.0 1.6 7.1 22.2 9.6 24.2 10.5 3.7 12.2 4.2 46.8 3.8 5.0 4.9 14.9 5.7 2.8 6.2 8.9 4.8 13.0 1.9 0.1 6.5 3.1 10.6 10.7 9.8 6.0 4.1 18.2 8.6 2.6 7.6 3.7 16.3 8.4 2.3 12.5 17.1 7.1 0.0 0.0 4.4 0.2 1.9 3.6 1.0 0.2 1.1 0.0 1.1 0.0 0.0 0.0 10.0 0.0 0.4 0.1 1.3 0.0 0.4 0.2 1.3 0.3 0.0 6.2 7.4 0.3 3.3 7.2 0.0 0.3 0.0 0.0 37.4 1.0 1.6 0.0 0.9 0.2 3.1 10.5 4.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 1.1 1.6 0.0 0.2 7.5 2.7 0.0 0.3 27.4 0.0 2.5 0.2 0.0 0.2 0.0 0.1 0.6 0.0 50.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 9.8 14.9 3.2 21.5 10.5 3.7 5.0 4.9 4.8 4.1 7.6 7.1 243.8 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.2 114.1 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 TAOK2 "KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973868-29992261 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.51e-4)" "prognostic favorable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favorable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" 31.4 36.0 23.4 14.7 21.2 12.7 30.8 18.0 26.1 24.8 11.9 21.8 17.3 25.9 11.1 20.8 22.6 12.0 32.6 23.0 18.9 22.7 17.6 34.0 14.4 21.0 20.0 24.1 19.5 17.4 29.4 19.4 18.9 22.5 8.5 14.3 20.5 13.3 23.4 22.4 24.4 13.3 15.3 33.8 21.8 34.8 20.8 13.2 25.4 12.7 10.5 22.4 21.6 19.0 22.2 41.8 22.4 35.1 25.8 17.1 34.2 40.0 21.1 26.4 24.4 33.6 28.7 23.8 32.8 28.8 18.0 33.9 20.4 20.0 14.1 37.5 43.3 25.8 46.2 34.8 18.7 25.5 47.5 20.0 17.1 28.1 11.2 18.5 44.7 22.4 23.5 23.6 25.8 41.0 29.8 36.0 21.5 16.4 27.6 54.2 32.5 22.2 16.6 20.5 26.1 20.8 22.8 30.2 12.1 14.4 37.5 28.5 62.9 45.0 20.7 32.4 23.6 34.2 23.7 22.1 27.6 28.8 33.7 0.3 0.7 0.4 0.7 0.7 0.8 0.5 0.7 0.6 0.4 0.6 0.4 0.3 1.2 0.5 0.4 0.8 0.9 0.6 23.4 21.2 18.0 26.1 23.0 18.9 21.0 20.0 18.9 15.3 20.8 19.0 52.0 9.6 11.5 21.9 6.3 10.7 4.6 7.5 7.4 14.6 10.5 5.7 9.8 7.2 9.1 9.2 39.6 7.8 7.6 27.0 1.9 8.5 3.9 8.7 9.5 35.3 13.1 3.4 7.9 12.0 6.2 9.7 14.3 8.9 3.8 16.0 47.2 11.8 9.8 10.1 10.7 16.8 12.2 11.2 11.1 4.4 12.5 8.2 7.2 7.5 9.0 8.4 11.3 9.0 12.7 16.1 14.8 12.8 5.9 7.4 27.2 8.0 10.0 21.4 6.6 8.7 8.7 19.7 21.6 9.1 9.7 12.0 9.2 16.0 14.7 7.4 TAS1R3 T1R3 ENSG00000169962 "Taste 1 receptor member 3" Q7RTX0 1 1331280-1335314 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 12.1;salivary gland: 7.9" "Cell type enhanced" "Detected in some" "B-cells: 2.9;Cardiomyocytes: 3.8;Muller glia cells: 1.3;Plasma cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 17 "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 17 "B-cells: 1.6" "Cell line enhanced" "Detected in some" "Karpas-707: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053439 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 20: HeLa - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "HPA053439: AB_2682150" "unprognostic (1.35e-2)" "unprognostic (1.45e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-3)" "unprognostic (4.32e-2)" "unprognostic (2.05e-1)" "unprognostic (6.95e-2)" "unprognostic (4.22e-1)" "unprognostic (8.44e-3)" "unprognostic (7.59e-3)" "unprognostic (8.37e-2)" "unprognostic (1.18e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-1)" 0.3 0.3 0.5 1.3 0.7 0.5 0.3 1.0 0.7 0.4 0.0 1.0 1.5 0.3 12.1 1.2 0.4 0.1 1.3 0.4 0.1 0.5 1.0 0.4 1.3 0.5 0.3 0.4 0.2 0.0 1.5 0.2 0.4 0.3 0.1 0.0 7.9 0.1 1.1 0.3 1.9 0.0 0.3 3.6 0.7 0.7 0.4 0.2 0.6 0.0 0.9 0.3 0.6 1.1 0.6 0.5 0.1 0.2 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.3 1.2 0.7 0.1 0.0 0.1 0.2 0.0 0.0 0.0 1.6 0.4 0.1 1.2 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 2.5 0.0 0.3 0.1 0.2 0.3 0.2 1.4 0.4 0.2 0.3 0.0 0.1 0.9 0.1 0.2 0.9 0.8 0.1 0.8 0.1 0.1 0.2 0.0 0.7 0.3 1.5 1.5 0.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 1.0 0.7 0.4 0.1 0.5 0.3 0.4 0.3 0.4 1.1 0.4 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.2 0.1 3.8 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.3 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 5.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 TASL "CXorf21, FLJ11577" ENSG00000120280 "TLR adaptor interacting with endolysosomal SLC15A4" Q9HAI6 X 30558809-30577766 "Disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.5;lymphoid tissue: 10.9" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "THP-1: 166.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001185 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA001185: AB_1078591" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (4.37e-2)" "unprognostic (2.27e-2)" "unprognostic (3.47e-2)" "unprognostic (5.25e-3)" "unprognostic (9.07e-3)" "unprognostic (5.94e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (3.43e-1)" "unprognostic (3.60e-1)" "unprognostic (1.66e-3)" "unprognostic (8.99e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-2)" "unprognostic (3.23e-2)" 1.8 1.8 0.6 10.9 0.6 19.5 2.1 0.7 1.0 1.1 1.1 3.5 4.7 0.6 0.4 1.6 0.8 3.9 0.6 0.7 0.6 1.1 2.4 4.7 10.5 1.3 1.1 0.3 0.3 0.7 0.3 2.9 1.3 1.0 3.4 0.2 1.0 0.6 0.1 0.7 3.0 2.2 0.9 9.8 3.6 0.3 1.5 5.8 0.6 0.4 10.2 4.1 0.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 13.8 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 21.5 0.0 0.0 0.0 20.5 0.0 21.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.0 0.0 0.0 0.0 0.0 0.1 15.0 1.6 7.5 0.0 23.9 0.0 8.6 21.9 24.1 1.6 19.8 0.3 23.0 2.0 1.1 25.3 23.6 1.8 1.3 30.6 7.1 44.4 45.9 3.4 8.0 0.6 0.6 0.7 1.0 0.7 0.6 1.3 1.1 1.3 0.9 1.5 2.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 TAT ENSG00000198650 "Tyrosine aminotransferase" P17735 16 71565660-71577092 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Aminotransferase, Transferase" "Disease variant, Mental retardation, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "liver: 1272.2" "Cell type enriched" "Detected in some" 43 "Hepatocytes: 4164.8" "Cancer enriched" "Detected in some" 10 "liver cancer: 152.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (3.66e-3)" "unprognostic (1.29e-1)" "unprognostic (8.17e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.01e-2)" "prognostic favorable (6.51e-4)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (2.27e-1)" "unprognostic (3.73e-3)" "unprognostic (1.88e-1)" "unprognostic (1.27e-4)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" "unprognostic (1.05e-2)" 0.1 0.0 0.0 0.1 0.0 0.1 58.9 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.4 1272.2 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.8 0.1 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.7 6.7 0.0 0.1 0.0 0.0 0.6 95.3 18.7 0.5 72.9 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.3 1.0 0.3 0.0 3.1 0.0 45.5 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.1 49.6 4164.8 0.0 0.0 0.0 0.0 0.0 72.3 0.0 0.7 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 2.7 0.2 0.3 1.0 0.0 0.0 0.1 1.3 1.3 0.0 0.0 0.0 3.9 0.0 0.1 0.0 TBC1D16 "FLJ20748, MGC25062" ENSG00000167291 "TBC1 domain family member 16" Q8TBP0 17 79932343-80035872 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 307.9" "Cancer enhanced" "Detected in all" "melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.3" "Lineage enhanced" "Detected in single" "monocytes: 2.3" "Cell line enhanced" "Detected in many" "ASC diff: 179.1;SK-MEL-30: 192.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024482, HPA065839" Approved Approved "Intermediate filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Intermediate filaments" "HPA024482: AB_1857790, HPA065839: AB_2685566" "unprognostic (4.53e-3)" "unprognostic (1.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.06e-2)" "unprognostic (4.92e-2)" "unprognostic (7.21e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (5.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-3)" "unprognostic (3.99e-3)" 37.3 8.1 17.6 8.7 24.8 0.9 18.4 24.4 14.6 10.4 5.3 8.0 7.9 12.4 11.5 10.1 12.9 9.5 10.7 10.6 15.2 27.7 7.4 9.0 7.8 18.0 22.7 11.7 15.7 12.9 7.0 7.5 16.0 17.7 5.9 7.6 29.4 10.8 5.1 17.3 9.0 10.5 13.0 7.3 8.4 4.1 38.9 4.0 10.1 6.7 3.5 8.6 6.2 17.4 30.3 28.2 43.1 50.8 179.1 93.7 8.2 17.3 17.1 10.7 12.0 53.6 10.3 0.1 11.9 29.2 20.3 9.4 45.8 16.2 8.2 1.5 21.5 0.0 13.3 25.1 30.5 0.6 4.1 106.1 28.1 23.2 16.7 17.1 45.9 19.8 7.2 19.6 20.2 18.4 8.1 2.7 51.8 39.3 15.4 25.4 27.2 17.5 12.6 36.5 43.8 56.8 15.4 42.5 192.4 26.7 27.9 13.6 31.3 37.1 26.1 29.5 15.3 59.9 11.4 3.3 15.9 11.2 47.8 0.0 0.1 0.0 0.0 1.9 0.2 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.0 2.3 0.0 0.0 0.2 17.6 24.8 24.4 14.6 10.6 15.2 18.0 22.7 16.0 13.0 38.9 17.4 5.7 0.0 7.9 15.7 1.7 5.5 5.2 4.3 2.8 8.5 12.3 7.5 8.1 17.2 5.5 7.3 10.4 6.1 0.3 3.1 9.8 15.1 0.9 15.3 22.7 10.4 31.8 3.6 7.3 22.1 1.5 17.5 9.7 26.0 7.6 23.8 14.6 17.9 3.2 307.9 8.9 6.3 14.2 58.4 3.1 2.2 5.9 6.4 76.5 37.5 0.9 23.1 2.1 14.6 4.9 17.4 4.8 7.9 0.4 12.5 3.5 13.5 8.2 7.0 6.6 19.3 10.3 0.3 4.3 5.8 4.5 1.9 2.7 7.6 7.0 5.9 TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 5 "monocytes: 38.2" "Cell line enhanced" "Detected in many" "ASC diff: 82.9;ASC TERT1: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA037496" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nuclear speckles" "CAB015211: , HPA037496: AB_2675507" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (4.25e-3)" "unprognostic (3.98e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-2)" "unprognostic (2.38e-1)" "unprognostic (8.53e-2)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (6.73e-2)" "unprognostic (7.98e-3)" 17.3 6.3 4.7 8.9 4.4 12.7 21.8 8.7 5.0 14.4 8.3 9.0 7.1 10.6 7.8 15.4 19.9 18.1 38.6 5.1 6.3 17.0 24.8 23.2 7.2 6.8 5.3 8.4 34.3 17.5 13.0 3.1 6.7 44.0 6.0 6.5 19.0 30.3 83.7 28.1 28.7 6.9 4.3 14.5 27.2 18.1 5.9 6.4 9.6 79.7 6.8 13.1 17.5 4.1 5.1 30.1 2.6 8.6 82.9 57.8 24.4 3.1 51.8 2.1 2.6 10.8 8.0 2.6 27.1 2.3 42.5 15.5 5.0 23.5 1.4 1.5 4.6 1.5 11.1 37.7 5.7 0.3 26.0 27.4 21.8 2.8 21.6 1.7 30.2 4.5 0.7 2.6 2.7 13.3 2.8 15.8 6.7 3.6 32.3 6.4 7.5 0.6 17.0 32.3 18.7 9.2 4.2 7.4 10.8 4.0 2.1 23.1 26.0 1.3 4.5 4.4 2.1 5.0 0.4 0.2 10.9 7.7 8.0 0.0 9.7 0.4 0.2 30.1 0.3 0.4 0.3 0.2 5.0 1.5 0.6 0.4 0.3 0.0 38.2 7.2 0.2 4.1 4.7 4.4 8.7 5.0 5.1 6.3 6.8 5.3 6.7 4.3 5.9 4.1 4.3 3.2 4.6 10.7 2.8 4.1 38.3 7.2 23.9 6.4 15.0 3.9 12.2 18.6 14.4 5.5 4.2 4.6 4.8 1.1 0.0 8.2 6.0 42.6 4.7 9.8 3.0 0.8 43.5 3.0 2.8 4.3 31.6 23.7 7.0 0.9 11.7 5.6 3.7 1.7 42.8 2.2 10.2 13.8 17.7 10.9 3.1 27.7 5.4 22.5 28.1 1.0 0.0 23.6 6.5 2.6 2.4 1.9 1.4 35.0 4.8 1.2 31.9 3.7 6.6 24.7 4.3 3.6 4.0 29.8 6.3 3.4 1.6 2.7 1.1 29.7 TBC1D9 "GRAMD9, KIAA0882, MDR1" ENSG00000109436 "TBC1 domain family member 9" Q6ZT07 4 140620782-140756385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 91.6" "Cancer enriched" "Detected in all" 7 "breast cancer: 85.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.9" "Group enriched" "Detected in many" 37 "B-cells: 5.9;dendritic cells: 3.2;monocytes: 1.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000262, HPA006503" Uncertain Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 35: Glandular cells - Unknown function" Cytosol "HPA000262: AB_2665956, HPA006503: AB_2667604" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.49e-2)" "unprognostic (3.00e-1)" "unprognostic (1.22e-2)" "unprognostic (9.17e-2)" "unprognostic (2.11e-3)" "unprognostic (2.64e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-3)" "unprognostic (6.77e-2)" "prognostic favorable (1.61e-6)" "unprognostic (2.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.72e-2)" "unprognostic (2.16e-2)" 18.2 9.2 7.2 15.2 7.9 2.0 48.7 22.5 9.4 12.9 35.2 7.3 8.2 8.3 7.8 9.1 10.0 13.8 8.5 8.4 15.3 15.7 12.6 16.3 15.1 7.9 9.6 15.9 9.1 9.8 6.3 20.5 15.4 14.6 6.6 21.0 8.8 21.3 2.2 3.2 12.8 7.7 6.4 33.7 16.8 3.3 12.9 5.6 5.8 6.9 19.4 15.8 7.1 3.3 0.9 11.9 10.9 9.4 26.0 24.3 22.3 15.3 16.3 10.8 13.7 2.4 10.4 0.1 9.5 19.9 13.4 2.4 13.7 10.8 10.1 0.0 7.7 7.0 8.5 10.4 9.4 0.9 1.1 20.1 17.7 9.4 37.2 31.2 30.3 3.7 0.0 0.0 10.2 12.0 1.6 0.1 1.7 12.7 10.4 7.7 17.9 18.1 12.3 22.0 16.0 11.4 15.8 27.4 10.5 18.4 6.4 0.4 47.7 28.3 8.5 18.6 13.3 0.0 0.0 0.1 17.2 1.3 15.7 0.0 1.7 0.0 0.0 1.3 0.0 5.9 0.0 0.0 2.9 2.9 0.0 0.0 0.0 0.0 0.5 3.2 0.0 0.7 7.2 7.9 22.5 9.4 8.4 15.3 7.9 9.6 15.4 6.4 12.9 3.3 49.4 54.5 9.3 4.6 42.1 4.6 10.6 21.4 4.0 35.4 91.6 39.4 8.1 17.2 15.1 55.2 4.2 14.1 14.0 8.3 7.9 13.6 0.5 49.4 20.9 32.6 7.7 0.4 54.8 17.2 4.7 15.1 8.2 61.4 0.0 8.0 17.2 23.9 18.3 10.1 66.2 6.6 24.4 39.3 30.3 1.3 13.1 44.8 8.8 78.7 39.5 43.5 1.0 27.6 2.6 12.2 5.8 26.7 25.0 16.3 6.1 5.7 15.9 7.6 0.0 2.8 11.1 0.8 1.7 10.4 3.8 43.2 3.7 16.0 3.1 16.0 TBX15 TBX14 ENSG00000092607 "T-box transcription factor 15" Q96SF7 1 118883046-118989556 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.8;skeletal muscle: 132.2;tongue: 114.7" "Cell type enhanced" "Detected in some" "Early spermatids: 8.2;Fibroblasts: 11.1;Hepatocytes: 15.3;Melanocytes: 7.2;Skeletal myocytes: 13.1;Smooth muscle cells: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 52.6;ASC TERT1: 22.1;BJ hTERT+ SV40 Large T+ RasG12V: 20.4;fHDF/TERT166: 28.2;HSkMC: 37.9;RH-30: 29.1;U-2197: 27.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.3" "HPA052245, HPA053713" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Centrosome "HPA052245: AB_2681771, HPA053713: " "unprognostic (1.94e-1)" "unprognostic (2.75e-3)" "unprognostic (1.92e-2)" "unprognostic (3.94e-2)" "unprognostic (5.72e-3)" "unprognostic (7.79e-2)" "unprognostic (5.82e-2)" "unprognostic (2.46e-1)" "unprognostic (3.00e-3)" "unprognostic (1.39e-1)" "unprognostic (3.81e-3)" "unprognostic (5.03e-2)" "prognostic unfavorable (5.57e-8)" "unprognostic (2.63e-2)" "unprognostic (3.90e-2)" "unprognostic (1.88e-3)" "unprognostic (2.31e-1)" 29.8 0.1 0.8 0.0 1.0 0.0 16.1 0.7 1.3 0.1 2.1 0.1 0.0 0.2 0.1 1.9 0.4 0.5 3.1 0.7 0.6 1.0 46.8 0.6 2.7 0.6 0.7 0.1 0.1 0.5 1.5 0.1 0.7 1.4 0.0 0.2 6.9 0.0 132.2 9.4 0.1 0.1 0.5 0.0 0.1 0.7 0.9 0.3 1.9 114.7 1.3 0.4 0.3 0.7 1.4 0.0 0.0 0.0 52.6 22.1 0.0 4.7 6.4 12.3 20.4 0.0 0.0 0.0 2.6 28.2 0.0 0.0 0.0 0.0 4.9 0.0 0.3 0.0 1.4 0.0 0.1 0.4 0.0 37.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 14.1 0.0 0.0 0.2 2.3 0.0 0.2 0.0 29.1 0.4 3.0 1.4 0.6 0.0 1.6 0.0 0.6 0.6 0.0 0.6 0.0 6.6 4.0 27.3 0.2 0.4 0.2 0.0 13.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.7 1.3 0.7 0.6 0.6 0.7 0.7 0.5 0.9 0.7 3.2 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.2 0.1 0.0 1.2 0.0 0.0 0.3 0.0 0.0 11.1 0.0 0.1 0.0 0.0 0.0 15.3 0.1 0.0 0.2 0.0 0.0 0.0 4.0 1.1 0.0 0.1 7.2 1.9 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.1 12.5 0.2 0.4 0.0 2.0 0.0 0.3 0.1 0.0 0.0 TBX2 ENSG00000121068 "T-box transcription factor 2" Q13207 17 61399843-61409466 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 62.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 134.1;Collecting duct cells: 95.6;Muller glia cells: 139.8;Sertoli cells: 170.9;Smooth muscle cells: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 129.3;MCF7: 78.5;SH-SY5Y: 65.4;SK-MEL-30: 49.3;WM-115: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA008586, CAB013636" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB013636: , HPA008586: AB_1080222" "unprognostic (6.18e-2)" "unprognostic (8.51e-2)" "unprognostic (4.50e-1)" "unprognostic (2.09e-1)" "unprognostic (1.36e-1)" "unprognostic (8.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (9.29e-2)" "unprognostic (2.10e-2)" "unprognostic (2.10e-1)" "unprognostic (2.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.37e-1)" "unprognostic (1.45e-1)" "unprognostic (6.34e-3)" 21.1 3.7 2.9 2.6 3.4 0.0 16.1 2.7 4.6 14.5 1.7 9.8 4.9 22.0 14.1 7.1 15.7 4.5 19.9 2.2 3.2 31.7 4.9 62.8 1.0 3.8 4.1 10.2 3.6 2.1 6.2 24.7 3.8 16.3 1.8 6.3 4.2 27.5 8.1 5.6 11.4 4.6 2.3 13.7 11.5 5.4 3.9 0.8 15.9 5.8 0.5 31.2 13.0 2.2 0.5 1.9 0.0 129.3 4.2 4.4 15.6 22.4 21.2 1.0 0.2 3.6 0.4 0.0 1.6 3.3 2.5 0.0 2.4 0.0 0.4 0.0 8.8 2.2 0.0 6.4 14.0 0.4 2.1 8.0 0.2 23.4 1.3 0.3 0.0 0.0 0.5 0.0 1.4 78.5 0.0 0.4 0.1 0.0 9.4 0.0 5.3 0.2 0.0 31.0 0.3 65.4 0.0 0.0 49.3 0.2 1.6 2.5 0.0 2.9 0.0 7.3 4.7 0.1 0.3 0.0 17.6 0.0 43.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.4 2.7 4.6 2.2 3.2 3.8 4.1 3.8 2.3 3.9 2.2 12.7 0.0 0.6 2.3 0.1 0.6 0.3 0.0 0.0 134.1 0.4 1.1 11.1 0.0 0.0 95.6 22.9 0.4 0.5 0.0 1.9 0.1 0.8 1.4 45.7 12.2 0.0 0.0 0.1 0.0 0.4 13.7 0.5 1.6 0.0 0.1 12.1 0.0 0.9 1.7 0.0 0.0 0.0 1.0 1.8 1.1 39.4 1.1 1.8 5.6 0.0 139.8 0.0 0.0 0.1 0.0 0.0 47.4 0.0 0.5 0.0 25.1 0.0 13.4 170.9 0.8 104.0 0.4 0.7 0.1 0.3 0.3 0.9 1.1 0.0 0.2 TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.1;lung: 3.3;lymphoid tissue: 11.7" "Cell type enhanced" "Detected in some" "dendritic cells: 92.8;NK-cells: 119.4;Plasma cells: 22.8;T-cells: 45.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Cell line enriched" "Detected in single" 113 "HDLM-2: 16.3" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.2" "CAB009524, CAB030043" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB009524: AB_2200557, CAB030043: AB_1595503" "unprognostic (3.31e-3)" "unprognostic (3.17e-3)" "unprognostic (1.17e-2)" "unprognostic (5.35e-6)" "unprognostic (3.93e-1)" "unprognostic (2.56e-4)" "unprognostic (5.86e-4)" "unprognostic (6.90e-2)" "unprognostic (3.63e-3)" "unprognostic (6.26e-4)" "unprognostic (1.43e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-4)" "unprognostic (7.92e-2)" "unprognostic (2.67e-1)" "unprognostic (9.19e-3)" "unprognostic (4.43e-3)" 0.9 0.4 0.3 1.9 0.3 11.1 0.4 0.3 0.3 0.4 0.4 0.5 0.9 0.3 0.4 0.3 0.4 0.8 0.3 0.2 0.3 0.5 1.2 3.3 7.5 0.4 0.3 0.2 0.2 0.0 0.2 0.2 0.3 0.4 0.5 0.0 0.6 0.2 0.5 0.2 1.6 0.4 0.3 11.7 1.2 0.4 0.3 1.0 0.7 0.2 2.2 0.6 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 3.6 2.0 3.1 8.9 0.0 0.5 0.4 7.8 0.2 14.3 0.0 0.1 0.1 2.4 0.3 0.3 0.3 0.3 0.2 0.3 0.4 0.3 0.3 0.3 0.3 0.3 1.1 0.0 0.6 0.0 7.6 0.0 0.0 0.0 0.6 0.0 0.6 0.9 1.3 1.5 0.0 0.0 0.0 0.1 92.8 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 1.3 0.1 0.0 0.0 0.2 1.1 0.2 2.5 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 1.9 0.0 1.9 0.8 0.0 119.4 0.0 0.1 0.0 0.0 0.0 22.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.1 0.0 45.6 0.0 0.0 0.0 TBX22 "CLPA, CPX" ENSG00000122145 "T-box transcription factor 22" Q9Y458 X 80014753-80031774 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "testis: 11.1;thyroid gland: 4.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HDLM-2: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (6.58e-2)" "unprognostic (6.31e-2)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 178.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 613.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favorable (3.28e-4)" 13.3 178.4 5.1 2.5 4.7 0.0 34.1 3.9 5.7 37.5 2.9 7.4 37.6 32.8 44.6 2.8 24.0 4.5 13.2 3.8 14.9 12.9 31.3 32.8 1.4 4.6 4.4 44.2 2.9 1.0 12.9 41.3 4.8 80.4 3.7 1.8 18.9 53.2 10.4 14.9 30.3 10.0 3.8 7.0 6.0 1.3 6.6 1.3 50.0 16.5 1.7 53.9 34.2 3.7 2.4 18.2 0.0 0.0 26.1 35.6 40.1 103.0 97.3 39.0 38.3 16.3 4.4 0.0 1.6 18.0 2.4 4.7 8.4 3.6 47.7 0.0 12.3 0.0 4.8 48.1 8.4 0.0 0.0 16.0 2.4 13.1 26.8 0.0 0.5 0.0 3.8 0.0 3.4 1.6 0.0 0.5 0.2 53.0 5.4 0.0 0.0 2.6 0.0 129.3 6.6 19.4 14.6 6.6 3.6 44.6 5.1 0.2 0.0 11.9 7.7 6.8 33.9 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.7 3.9 5.7 3.8 14.9 4.6 4.4 4.8 3.8 6.6 3.7 48.9 0.0 1.9 0.3 1.8 9.8 85.2 5.8 7.4 14.3 110.3 80.5 12.5 0.0 1.1 35.0 4.2 60.7 0.7 12.0 0.0 0.6 1.5 3.3 144.7 38.6 4.9 0.0 0.0 0.0 7.0 41.3 5.1 3.8 0.0 3.9 1.1 40.2 6.1 1.7 0.0 23.9 4.1 0.9 4.6 2.8 5.3 2.9 3.6 14.0 0.0 1.9 0.0 0.0 0.0 0.3 22.4 6.0 0.0 72.4 37.9 0.1 0.4 2.0 39.5 27.2 58.2 0.1 3.8 3.2 9.8 613.9 2.0 112.0 12.1 69.1 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adipocytes: 820.0;Endothelial cells: 574.5;Inhibitory neurons: 1177.6;Oligodendrocyte precursor cells: 719.8;Oligodendrocytes: 573.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.1" "Group enriched" "Detected in many" 14 "memory B-cell: 173.6;naive B-cell: 146.8;plasmacytoid DC: 559.8" "Group enriched" "Detected in many" 33 "B-cells: 173.6;dendritic cells: 559.8" "Cell line enhanced" "Detected in many" "HDLM-2: 140.4;SH-SY5Y: 157.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" 20.3 9.6 3.7 12.8 12.5 9.5 11.6 65.1 26.5 28.5 0.0 7.4 5.1 23.0 2.1 9.7 13.4 17.4 17.5 29.8 0.0 4.4 4.4 15.5 14.7 5.5 1.0 25.9 5.8 8.0 6.5 28.9 3.9 6.6 7.9 14.0 6.8 10.2 6.1 6.4 5.0 24.1 2.2 13.1 6.0 15.4 2.4 9.8 13.3 16.7 14.7 13.1 7.3 14.4 0.1 4.1 36.8 11.4 8.5 14.4 0.1 18.4 40.6 13.2 17.2 23.1 3.6 28.8 0.1 41.9 2.7 4.5 17.9 17.1 9.2 140.4 13.9 12.1 0.1 0.0 4.0 5.3 2.8 19.6 5.3 18.5 0.7 9.1 45.8 1.6 19.5 22.0 11.0 0.0 7.6 0.0 10.4 0.1 2.4 41.6 14.9 65.4 0.0 0.9 12.6 157.7 0.0 1.5 0.0 11.1 1.6 1.3 49.1 48.5 17.4 2.1 14.6 16.3 32.2 25.7 11.0 5.2 15.5 0.9 7.4 0.8 0.9 8.3 0.7 173.6 0.2 0.5 20.6 146.8 0.5 0.3 1.8 11.2 7.4 559.8 0.7 11.3 3.7 12.5 65.1 26.5 29.8 0.0 5.5 1.0 3.9 2.2 2.4 14.4 820.0 6.4 13.1 501.1 217.4 117.0 37.8 34.0 80.8 293.0 6.5 23.4 35.5 4.3 32.6 22.0 83.4 1.8 446.8 0.1 0.0 1.5 103.2 17.5 201.4 574.5 5.4 34.2 503.8 7.1 1.5 296.7 1.5 12.2 13.9 105.7 316.3 6.6 39.6 25.2 1177.6 0.3 26.4 112.4 129.2 116.3 205.3 80.4 64.0 474.1 32.7 372.8 13.4 719.8 573.6 2.1 0.1 182.1 131.7 20.8 0.0 2.3 25.9 54.7 236.7 304.5 221.0 8.7 14.5 47.5 84.4 2.6 15.1 164.8 0.2 17.8 TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late spermatids: 89.0;Spermatocytes: 103.7" "Cancer enhanced" "Detected in many" "testis cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.0;TIME: 1.4" "Not detected" "Not detected" HPA054327 Approved Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA054327: AB_2682452" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.33e-3)" "unprognostic (9.69e-3)" "unprognostic (5.80e-3)" "unprognostic (2.99e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (8.04e-5)" "unprognostic (1.62e-1)" 11.1 4.5 3.7 0.5 3.7 0.1 6.8 3.1 3.7 5.1 3.3 2.8 0.7 4.2 2.3 2.4 6.5 1.6 7.6 3.3 3.2 3.5 4.5 8.1 0.8 3.2 3.5 10.1 0.9 0.9 2.6 1.7 3.3 3.9 1.3 0.1 1.8 1.2 1.9 2.3 3.5 1.8 3.2 8.9 1.9 55.6 3.7 0.5 11.0 1.4 0.4 3.9 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.7 3.1 3.7 3.3 3.2 3.2 3.5 3.3 3.2 3.7 3.1 10.0 3.2 6.7 4.9 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.5 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.8 0.0 0.1 8.2 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 1.3 0.7 6.1 0.4 0.4 0.0 0.5 0.0 0.0 4.0 2.1 89.0 2.5 1.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 103.7 16.5 0.1 0.3 0.0 0.0 0.1 0.0 0.0 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TELO2 "hCLK2, KIAA0683, TEL2" ENSG00000100726 "Telomere maintenance 2" Q9Y4R8 16 1493344-1510457 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041348, HPA041473" Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Cytosol" "HPA041348: AB_10794514, HPA041473: AB_10795593" "unprognostic (1.27e-1)" "unprognostic (2.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-2)" "unprognostic (2.94e-2)" "unprognostic (5.99e-3)" "unprognostic (1.47e-3)" "unprognostic (2.21e-1)" "unprognostic (6.75e-2)" "unprognostic (3.15e-3)" 12.3 13.2 7.3 7.6 7.2 11.3 13.4 8.8 11.0 15.2 5.7 12.6 8.9 14.1 1.1 14.4 15.1 3.7 13.2 6.9 6.4 13.6 14.8 11.6 8.1 10.2 7.6 14.4 12.2 4.3 12.5 4.8 7.6 15.8 1.4 1.8 11.4 4.8 17.0 14.4 14.4 2.4 6.4 18.6 11.9 10.0 7.6 5.8 13.2 4.9 3.1 13.6 13.9 8.3 19.7 28.8 8.8 16.8 3.4 3.6 33.9 30.5 5.7 14.4 10.4 37.0 18.3 28.8 25.8 4.9 7.1 20.5 6.3 11.6 2.7 16.9 55.1 16.5 36.7 21.8 5.7 21.0 23.9 7.0 4.3 13.4 2.8 4.9 8.6 24.6 43.2 10.1 5.8 66.3 24.9 56.1 28.2 6.9 23.9 73.5 12.3 29.4 5.4 18.3 36.8 20.6 26.5 24.8 9.8 3.3 23.2 25.3 13.8 31.2 21.7 30.5 25.8 18.2 12.6 53.3 9.9 29.3 26.7 0.0 5.7 2.9 4.1 7.2 3.9 4.1 2.9 3.4 6.9 6.0 3.1 2.5 0.5 3.4 10.7 4.3 2.7 4.7 7.3 7.2 8.8 11.0 6.9 6.4 10.2 7.6 7.6 6.4 7.6 8.3 15.8 0.0 2.7 18.9 15.2 6.9 7.8 10.4 10.2 13.7 12.7 9.8 1.6 11.5 6.3 9.2 12.5 25.5 9.1 19.4 5.9 8.2 2.0 8.4 11.0 9.6 2.4 10.8 5.3 7.2 20.2 11.4 15.8 9.2 2.5 21.2 8.9 12.3 19.6 18.5 6.4 17.2 8.2 11.8 7.0 1.9 7.5 8.6 8.8 10.3 13.3 17.3 8.2 8.5 7.0 6.9 5.5 14.7 8.7 8.8 13.7 6.3 5.1 20.1 13.1 9.9 11.4 9.8 8.2 10.3 6.5 22.0 9.6 19.0 23.5 5.1 TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8;placenta: 13.1" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 635.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;BEWO: 63.3;HDLM-2: 90.0;T-47d: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047043 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA047043: AB_2679914" "unprognostic (5.79e-2)" "unprognostic (3.01e-2)" "unprognostic (6.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (8.28e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (4.85e-2)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (5.25e-4)" 5.0 5.1 12.0 1.6 18.4 0.0 2.0 0.0 12.3 1.5 0.0 4.3 0.8 2.9 0.6 0.8 1.0 2.4 1.4 21.8 8.1 0.9 0.3 0.8 0.8 2.8 7.3 3.8 1.2 5.1 4.5 13.1 0.0 3.7 0.8 3.9 0.6 3.6 2.1 0.4 0.9 2.3 0.8 2.2 0.7 2.1 7.4 2.8 6.1 4.3 1.2 1.6 1.4 2.0 0.3 2.6 66.3 0.4 13.2 23.5 63.3 7.8 2.7 6.9 6.1 33.9 17.6 0.0 0.9 52.6 28.6 3.3 16.0 3.4 6.8 90.0 26.7 0.0 0.0 0.0 1.3 0.0 0.0 31.2 1.2 21.5 15.0 15.4 9.6 0.0 0.0 0.4 10.6 2.3 0.1 0.1 21.4 0.0 2.8 0.0 17.1 0.2 0.1 0.1 27.2 25.2 4.0 0.5 0.1 35.8 86.0 3.4 21.2 53.7 38.2 0.2 39.6 0.0 0.0 0.0 28.2 0.0 40.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 18.4 0.0 12.3 21.8 8.1 2.8 7.3 0.0 0.8 7.4 2.0 0.1 0.0 0.0 23.8 0.0 0.4 0.2 0.7 1.8 50.8 1.6 2.2 3.9 0.0 0.1 3.7 4.2 112.7 0.0 0.0 1.9 0.1 12.4 0.1 4.5 0.7 5.3 0.0 115.6 1.8 54.6 4.1 0.0 0.6 0.0 7.7 1.1 0.7 10.4 5.0 635.6 0.0 0.0 0.0 0.7 3.2 8.4 0.0 1.8 8.4 0.0 10.6 0.0 12.1 24.4 0.4 0.0 2.6 0.0 0.4 0.0 0.3 0.0 3.1 0.0 4.8 3.2 3.8 7.2 1.8 0.0 133.4 0.1 4.1 0.1 0.1 TENT5A "C6orf37, FAM46A, FLJ20037" ENSG00000112773 "Terminal nucleotidyltransferase 5A" Q96IP4 6 81491439-81752774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 225.9;salivary gland: 104.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 73.1;Endometrial stromal cells: 70.6;Extravillous trophoblasts: 115.4;Glandular and luminal cells: 176.7;Syncytiotrophoblasts: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 81.9;HeLa: 86.1;HL-60: 95.6;THP-1: 162.0;U-937: 72.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051067, HPA067140" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA051067: , HPA067140: AB_2685788" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (5.39e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (2.62e-3)" "unprognostic (5.93e-2)" "unprognostic (2.48e-2)" "unprognostic (2.53e-1)" "unprognostic (1.03e-1)" "unprognostic (1.40e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (7.18e-2)" "unprognostic (6.38e-2)" "unprognostic (9.25e-2)" "unprognostic (9.66e-2)" 13.5 21.3 4.3 7.9 4.6 225.9 12.2 9.0 5.8 21.3 9.9 17.2 16.4 10.2 19.7 4.4 12.0 32.3 21.7 4.0 14.0 6.4 35.9 9.1 5.2 7.8 7.1 23.6 8.3 9.4 17.4 18.7 6.1 9.9 16.9 8.7 104.4 24.8 2.1 18.7 22.2 11.1 5.0 9.9 37.8 3.7 6.7 2.9 8.8 5.1 4.3 16.6 8.8 5.3 3.5 5.0 3.3 0.2 67.9 29.8 6.2 27.0 19.2 15.7 23.5 51.0 2.6 0.3 1.0 81.9 10.0 2.9 2.4 4.2 11.5 0.0 6.2 0.1 86.1 8.0 21.2 95.6 7.1 13.2 2.4 12.3 2.1 51.2 2.0 0.8 1.4 0.0 10.6 14.7 0.0 67.2 0.9 29.2 3.8 0.0 28.8 0.1 2.1 6.2 3.3 4.4 12.1 5.2 8.3 9.9 1.2 162.0 4.5 17.9 3.8 7.6 7.6 0.4 0.3 0.3 25.3 72.7 7.8 37.3 29.9 46.3 11.5 29.6 6.8 18.2 4.3 5.7 24.2 21.0 8.1 8.0 13.8 16.9 47.3 8.5 5.6 14.0 4.3 4.6 9.0 5.8 4.0 14.0 7.8 7.1 6.1 5.0 6.7 5.3 22.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 40.8 44.2 0.0 0.0 0.0 5.5 0.0 39.9 43.1 0.0 3.9 30.5 0.0 73.1 70.6 2.9 0.0 0.0 0.0 23.4 115.4 32.7 0.0 176.7 0.0 40.9 0.0 0.0 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 26.7 0.0 0.0 5.9 0.0 0.0 3.6 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 162.0 9.4 12.6 0.0 0.0 TESK1 ENSG00000107140 "Testis associated actin remodelling kinase 1" Q15569 9 35605262-35610041 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "unprognostic (5.17e-2)" "unprognostic (2.82e-1)" "unprognostic (4.96e-3)" "unprognostic (5.18e-2)" "unprognostic (2.04e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (1.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.66e-3)" "unprognostic (1.22e-2)" "unprognostic (2.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-3)" 40.2 44.7 24.4 11.2 22.0 6.1 33.5 17.9 25.9 22.6 14.8 29.9 13.3 25.7 11.1 12.8 18.7 13.0 19.2 22.0 21.3 18.0 13.8 19.9 11.9 20.6 24.2 15.9 16.0 16.8 26.6 9.1 21.8 22.4 8.5 6.7 17.4 19.8 69.2 19.1 18.9 17.1 18.2 16.2 22.2 57.0 28.1 10.4 19.0 27.6 8.5 27.9 16.0 20.4 17.0 16.0 10.7 16.9 42.5 17.5 12.1 19.7 17.3 17.8 11.3 9.3 4.8 30.9 10.3 19.7 47.1 5.8 6.8 14.1 3.4 20.0 9.2 4.6 14.1 8.4 24.4 4.0 14.6 17.2 21.8 13.9 19.0 18.9 12.6 15.3 5.3 11.3 18.0 19.1 7.9 18.4 6.2 16.1 18.6 12.9 6.6 7.3 13.1 8.0 8.8 10.3 11.2 13.0 8.1 7.3 15.9 5.7 11.1 39.2 16.2 27.9 12.0 6.0 10.2 11.2 28.2 4.6 9.1 0.0 0.6 0.1 1.1 0.1 1.0 0.3 0.4 1.8 0.8 0.2 0.5 0.5 0.0 0.9 0.3 0.8 0.1 0.7 24.4 22.0 17.9 25.9 22.0 21.3 20.6 24.2 21.8 18.2 28.1 20.4 13.4 6.4 7.7 9.1 8.9 14.4 6.3 5.9 4.6 10.9 13.9 11.0 1.9 7.2 4.2 7.3 8.4 3.8 20.0 19.9 1.9 6.6 35.1 5.6 9.2 9.7 9.5 1.7 6.5 10.4 8.6 9.0 18.8 11.2 1.3 10.1 10.8 8.4 13.9 13.5 8.5 14.8 0.0 7.8 22.4 34.9 12.2 19.3 14.2 2.8 6.3 12.6 20.6 4.5 6.8 10.2 11.0 14.3 10.7 19.2 13.4 7.8 4.2 15.3 6.6 10.1 10.9 14.8 10.0 4.7 13.9 3.3 11.8 5.4 7.3 9.7 TESMIN "CXCDC2, MTL5" ENSG00000132749 "Testis expressed metallothionein like protein" Q9Y4I5 11 68707440-68751520 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 52.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.6;Breast myoepithelial cells: 7.4;Endometrial ciliated cells: 31.5;Glandular and luminal cells: 27.0;Proximal tubular cells: 11.5" "Cancer enhanced" "Detected in many" "breast cancer: 6.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 11.9;T-47d: 23.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018539 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA018539: " "unprognostic (1.99e-1)" "unprognostic (3.97e-3)" "unprognostic (1.34e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (3.22e-2)" "unprognostic (6.71e-2)" "unprognostic (1.76e-2)" "unprognostic (6.99e-3)" "unprognostic (2.54e-1)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (8.47e-2)" "unprognostic (5.27e-2)" "unprognostic (6.39e-2)" "unprognostic (2.99e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-1)" 0.3 0.5 0.7 1.0 0.7 7.4 4.3 0.6 0.6 0.7 0.6 2.5 1.4 0.7 0.7 1.6 1.7 0.4 0.2 0.5 0.8 3.1 0.4 0.4 1.3 1.2 0.7 0.8 1.1 2.1 2.3 0.3 1.2 2.3 2.9 1.5 1.9 1.1 0.0 0.6 1.4 0.4 0.5 1.3 0.9 52.5 0.7 2.1 1.1 0.1 1.1 0.4 0.9 0.5 7.2 3.1 1.3 0.1 0.0 0.0 3.5 1.6 0.8 2.2 1.0 0.9 7.1 2.9 1.6 0.3 0.0 3.4 1.0 1.4 1.7 3.0 2.5 2.1 1.0 0.0 0.0 1.5 11.9 0.0 3.8 0.1 2.2 3.0 0.7 3.4 4.5 5.4 0.3 4.8 0.8 4.2 7.3 3.3 3.1 1.9 0.4 0.8 2.6 0.1 4.4 4.7 0.0 1.5 0.0 3.7 23.8 10.0 2.7 0.2 0.5 0.2 0.1 2.1 2.0 2.8 0.1 4.2 1.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.7 0.7 0.6 0.6 0.5 0.8 1.2 0.7 1.2 0.5 0.7 0.5 0.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 9.6 7.4 0.0 0.0 0.6 0.0 0.0 1.8 0.7 0.0 5.9 6.3 0.0 31.5 2.6 0.3 0.0 0.0 0.0 4.0 4.7 0.3 0.0 27.0 2.5 4.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.5 0.0 0.0 11.5 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.1 0.2 0.0 0.0 TFAP2B AP2-B ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 33.3;retina: 14.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 145.7;Bipolar cells: 76.4;Horizontal cells: 437.4;Melanocytes: 106.7" "Cancer enriched" "Detected in some" 8 "breast cancer: 12.1" "Group enriched" "Detected in many" 6 "cerebellum: 3.5;medulla oblongata: 3.9;midbrain: 9.0;pons: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 109.6;SH-SY5Y: 208.1" "Region enhanced" "Detected in many" "cerebellum: 10.0" "Low region specificity" "Detected in many" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA034683: AB_10670966, HPA062942: AB_2684909" "unprognostic (2.02e-1)" "unprognostic (2.29e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-4)" "unprognostic (9.76e-2)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.57e-1)" "unprognostic (6.58e-6)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (7.17e-3)" 0.1 3.4 0.0 0.0 0.0 0.0 8.2 3.5 0.1 0.1 0.0 0.1 0.0 0.0 33.3 3.9 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 3.9 9.0 0.0 0.0 0.0 0.6 0.2 10.2 0.0 0.0 14.8 6.4 0.7 0.0 8.6 0.0 0.0 0.6 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 109.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 35.5 0.1 0.2 208.1 0.0 0.8 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.1 3.9 9.0 10.2 0.6 1.1 0.2 0.2 0.0 0.0 0.0 0.0 11.7 0.0 0.0 145.7 76.4 43.0 29.7 0.9 0.0 0.0 51.5 8.4 14.9 0.1 0.0 54.8 0.0 17.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 437.4 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.5 106.7 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.7 0.0 11.8 0.0 0.0 0.3 1.9 0.6 31.1 4.3 4.9 0.2 0.0 0.0 0.0 TFE3 "bHLHe33, TFEA" ENSG00000068323 "Transcription factor binding to IGHM enhancer 3" P19532 X 49028726-49043410 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.5" "Group enriched" "Detected in many" 4 "granulocytes: 12.5;monocytes: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023881 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA023881: AB_1857931" "unprognostic (2.68e-2)" "unprognostic (2.89e-3)" "unprognostic (2.40e-2)" "unprognostic (5.36e-2)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (6.03e-5)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "unprognostic (4.32e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.19e-8)" "unprognostic (1.93e-1)" "unprognostic (8.77e-2)" "unprognostic (4.19e-2)" "unprognostic (6.25e-1)" 31.3 23.6 27.8 16.8 27.3 24.1 22.9 25.8 26.9 24.1 23.3 23.6 10.8 24.7 21.1 15.6 26.2 18.5 17.2 25.7 29.4 15.1 12.6 29.2 11.8 37.2 30.9 25.8 12.4 25.1 18.4 20.8 28.7 17.2 11.5 14.8 13.4 28.3 17.0 20.5 14.7 24.7 27.5 22.5 16.8 5.9 32.2 10.7 20.0 14.0 13.2 25.0 20.5 25.6 32.8 41.5 14.6 44.6 48.6 45.1 12.5 40.6 55.8 49.7 38.2 23.3 26.8 10.2 18.0 65.7 48.6 25.5 25.4 40.2 44.8 24.4 11.8 8.3 39.6 26.2 69.0 10.0 28.3 38.5 32.3 64.4 50.1 47.8 26.3 8.4 19.8 55.9 49.2 20.6 7.5 17.2 36.3 11.0 34.1 11.9 22.2 26.6 43.1 18.0 12.4 12.4 44.8 19.0 17.9 52.5 27.6 15.0 48.5 47.1 48.7 48.0 27.3 30.1 29.7 8.0 56.1 14.0 33.2 0.0 4.8 1.8 0.6 4.7 1.1 0.5 0.9 0.5 2.2 1.0 0.6 0.5 12.5 0.4 6.3 0.5 1.3 2.6 27.8 27.3 25.8 26.9 25.7 29.4 37.2 30.9 28.7 27.5 32.2 25.6 13.8 16.0 8.8 13.7 9.8 19.8 19.7 11.2 30.1 6.8 10.9 9.4 8.1 15.7 11.8 20.2 4.2 16.0 4.4 14.3 9.8 17.7 0.7 10.9 15.3 17.5 12.5 5.2 7.5 15.8 9.4 20.2 14.3 14.8 5.7 12.0 10.8 15.0 22.3 18.5 7.2 8.2 0.0 21.7 29.4 2.2 27.4 20.5 8.8 11.2 15.5 12.0 4.1 6.0 7.7 21.4 13.7 24.5 12.9 20.2 10.6 12.1 7.0 5.6 13.1 18.5 14.3 2.2 0.8 18.9 22.0 37.1 8.6 13.9 7.5 19.6 TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;kidney: 20.5;lymphoid tissue: 22.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 45.5;Kupffer cells: 56.3;Macrophages: 61.6;Microglial cells: 60.0;monocytes: 44.1;Proximal tubular cells: 77.8" "Cancer enhanced" "Detected in many" "renal cancer: 5.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Cell line enhanced" "Detected in some" "HEL: 15.9;HUVEC TERT2: 11.0;THP-1: 21.5;TIME: 12.5;U-937: 24.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB032260, HPA063577" Approved Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB032260: AB_2202845, HPA063577: AB_2685047" "unprognostic (1.36e-1)" "unprognostic (1.08e-2)" "unprognostic (8.70e-2)" "unprognostic (1.91e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.26e-2)" "unprognostic (2.15e-1)" "unprognostic (6.54e-2)" "unprognostic (2.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.05e-3)" "unprognostic (2.92e-1)" "unprognostic (4.14e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-2)" 3.5 2.4 1.3 19.2 1.2 17.2 2.6 1.5 1.6 1.9 2.1 2.7 4.2 1.4 0.6 1.0 1.0 4.9 1.0 0.8 1.7 20.5 3.1 9.9 22.1 3.3 1.9 1.3 1.0 0.4 0.6 4.7 2.7 1.0 4.2 0.1 1.3 0.9 0.3 0.4 9.7 3.1 2.7 14.6 3.0 1.6 3.7 2.8 0.9 0.4 12.6 4.0 0.6 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 1.7 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 21.5 12.5 2.1 0.2 1.3 0.0 5.5 0.0 0.0 0.1 24.4 1.1 0.0 7.1 0.0 0.0 2.8 0.0 3.8 0.0 0.0 6.3 2.5 0.0 0.0 0.1 0.0 0.4 3.3 0.0 1.5 1.3 1.2 1.5 1.6 0.8 1.7 3.3 1.9 2.7 2.7 3.7 4.8 0.5 0.0 2.2 0.3 18.1 0.5 0.0 0.0 0.0 0.0 0.3 0.8 0.8 1.5 0.0 3.7 0.0 0.2 8.3 0.0 0.0 0.0 2.4 0.0 0.0 1.7 0.0 7.2 0.6 0.0 0.3 0.4 0.0 0.0 2.5 0.0 0.0 0.0 45.5 0.0 0.5 0.4 0.0 56.3 17.8 3.8 0.0 61.6 0.0 60.0 44.1 0.0 1.0 1.0 0.1 0.1 0.0 0.0 1.3 0.1 15.6 77.8 0.0 0.0 0.0 0.3 0.1 0.3 2.5 0.1 0.4 0.8 0.8 0.1 0.7 0.1 TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.3;placenta: 191.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2284.2;Hepatic stellate cells: 872.4;Syncytiotrophoblasts: 879.2" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.3;neutrophil: 1.3;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "HHSteC: 386.2;HUVEC TERT2: 742.5;LHCN-M2: 459.9;TIME: 451.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" NA NA 58100000 87000000 "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" 67.5 12.6 2.6 20.5 3.4 8.2 52.3 4.9 5.8 41.5 7.4 23.3 52.5 25.7 18.5 33.3 35.6 57.6 38.5 4.1 2.2 56.3 272.3 126.7 33.3 6.8 2.5 26.5 25.0 7.1 6.1 191.2 3.9 15.7 27.4 4.5 15.0 12.8 26.8 19.8 41.8 30.7 3.7 20.7 19.2 6.9 3.6 11.1 36.2 42.8 17.7 52.9 29.8 3.2 38.9 24.7 29.3 0.8 224.3 267.7 0.7 66.0 156.3 42.7 65.1 22.6 192.6 0.7 27.3 52.7 74.7 2.1 15.9 3.6 110.3 1.9 7.6 12.3 73.8 197.3 386.2 0.9 0.4 123.1 5.1 232.8 61.9 93.4 742.5 0.7 31.2 0.7 459.9 35.4 4.6 0.7 22.9 0.8 68.8 0.3 40.2 0.3 72.9 1.4 0.3 0.5 56.7 2.1 3.5 95.8 0.7 0.2 451.4 30.6 29.0 61.4 13.5 1.1 1.7 0.4 239.4 0.6 35.4 3.3 0.2 0.2 0.2 0.1 0.1 0.4 0.1 0.0 0.2 0.5 0.2 0.2 1.3 0.5 0.1 2.7 0.1 2.3 2.6 3.4 4.9 5.8 4.1 2.2 6.8 2.5 3.9 3.7 3.6 3.2 99.2 35.3 335.5 1.3 4.4 20.8 2.9 33.5 4.6 0.6 16.1 9.1 7.0 173.0 102.5 38.6 0.0 59.5 4.8 0.5 13.7 140.0 41.5 7.3 74.2 287.1 105.0 43.1 0.7 273.1 2284.2 283.0 12.2 5.3 13.9 1.5 872.4 382.1 50.2 1.7 0.2 11.3 158.7 63.7 41.3 15.2 171.8 21.9 26.6 13.1 33.7 33.1 1.0 0.0 0.1 157.6 34.1 70.0 9.5 8.0 36.6 109.4 45.2 1.1 216.9 141.2 127.8 2.7 0.5 10.2 18.5 879.2 8.1 30.6 18.5 16.7 TGFB1I1 "ARA55, Hic-5, TSC-5" ENSG00000140682 "Transforming growth factor beta 1 induced transcript 1" O43294 16 31471585-31477960 "Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 265.6;intestine: 264.4" "Cell type enhanced" "Detected in many" "Leydig cells: 92.2;Peritubular cells: 179.0;Sertoli cells: 223.5;Smooth muscle cells: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 100.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB020844 Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 800000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" Cytosol "CAB020844: " "unprognostic (5.80e-2)" "unprognostic (3.09e-2)" "unprognostic (5.34e-2)" "unprognostic (1.18e-1)" "unprognostic (6.64e-2)" "unprognostic (9.52e-2)" "unprognostic (1.89e-1)" "unprognostic (4.95e-2)" "unprognostic (4.19e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.06e-8)" "unprognostic (1.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.73e-5)" 65.5 17.0 4.8 22.7 5.1 1.0 52.8 4.6 6.9 119.0 4.4 264.4 14.5 265.6 12.4 38.2 143.2 14.4 48.5 4.6 4.7 26.6 9.7 54.7 4.8 5.6 4.6 78.6 8.2 8.6 8.2 19.7 5.0 87.6 23.9 0.7 21.0 80.8 13.1 28.5 61.7 106.1 4.7 33.0 78.5 10.2 5.1 1.4 26.8 10.5 4.9 171.1 73.6 4.4 13.3 16.6 25.9 0.0 25.4 46.1 0.3 70.8 64.8 43.6 30.1 6.6 4.5 0.0 65.1 62.3 29.1 20.6 6.0 13.3 56.4 0.1 0.3 17.5 29.1 3.7 67.4 0.0 19.8 31.1 18.7 27.5 16.3 100.0 29.2 0.0 1.5 0.0 51.9 0.1 0.0 1.6 1.4 1.4 16.2 0.0 30.9 0.1 12.5 6.6 0.0 19.0 27.5 0.2 14.1 20.9 0.1 1.7 82.4 79.8 19.2 21.4 31.8 0.1 0.1 0.2 34.9 0.8 49.6 9.5 0.0 0.1 0.2 0.0 0.3 0.9 0.9 0.1 0.0 0.2 0.1 0.6 0.2 0.0 0.0 0.3 1.6 1.3 4.8 5.1 4.6 6.9 4.6 4.7 5.6 4.6 5.0 4.7 5.1 4.4 76.9 6.4 4.8 0.0 0.4 12.6 23.9 34.8 14.8 0.4 4.1 71.5 13.4 5.7 3.4 7.3 0.0 1.2 1.5 1.8 7.9 33.3 1.2 3.6 76.2 48.8 0.0 11.0 0.1 22.5 1.2 64.4 4.6 2.9 6.3 35.3 29.6 0.3 14.6 0.0 0.1 4.7 0.0 0.3 15.4 3.3 92.2 9.3 40.9 2.8 4.2 7.0 0.0 3.5 0.1 28.4 2.2 179.0 1.4 20.1 13.3 19.7 1.1 1.4 223.5 17.4 176.0 1.5 3.6 1.9 11.2 1.8 2.6 20.3 5.3 4.6 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 THBD CD141 ENSG00000178726 Thrombomodulin P07204 20 23045633-23049672 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant, Hemolytic uremic syndrome, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 254.3;Endothelial cells: 200.6;Langerhans cells: 138.1;Leydig cells: 130.8;Macrophages: 130.9;Peritubular cells: 259.2;Squamous epithelial cells: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 24.6" "Group enriched" "Detected in many" 7 "dendritic cells: 10.8;granulocytes: 24.6;monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;CAPAN-2: 39.2;EFO-21: 33.5;HaCaT: 33.1;hTCEpi: 42.6;OE19: 29.8;THP-1: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002425, HPA002982" Supported Approved Nucleoplasm,Cytosol NA NA 5550000 1300000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "CAB002425: AB_563497, HPA002982: AB_1078444" "unprognostic (1.96e-1)" "unprognostic (2.93e-3)" "unprognostic (8.70e-2)" "unprognostic (3.00e-2)" "unprognostic (3.07e-2)" "unprognostic (1.88e-1)" "unprognostic (7.81e-3)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.33e-2)" "unprognostic (2.23e-2)" "unprognostic (7.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.58e-3)" "unprognostic (9.71e-2)" 65.4 11.4 2.0 19.6 1.8 15.5 25.5 1.6 3.2 16.7 3.4 16.5 5.5 12.6 3.1 36.8 27.5 26.5 31.0 2.4 3.0 19.7 9.7 56.7 14.5 4.1 2.7 6.9 13.2 9.9 20.4 28.5 2.8 8.0 5.9 0.2 10.8 4.6 40.7 71.4 20.0 15.6 3.0 43.6 30.8 7.6 8.5 5.1 35.5 17.5 8.0 20.8 21.0 2.4 11.5 9.9 0.3 0.0 24.3 1.4 0.2 0.2 0.0 0.0 0.0 0.0 39.2 0.0 33.5 3.4 1.7 33.1 0.0 1.8 0.0 0.0 0.1 0.1 1.0 0.0 4.7 0.0 0.2 1.1 42.6 0.7 2.8 23.0 11.0 0.0 4.2 0.0 0.9 0.8 0.0 4.2 0.1 29.8 1.6 0.0 0.0 4.9 0.2 16.2 0.7 0.0 9.4 1.2 17.4 2.9 0.0 24.8 21.7 0.1 0.6 3.2 0.0 0.0 0.0 0.0 2.0 5.8 0.8 0.0 4.1 0.0 0.0 9.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 24.6 2.0 8.7 10.8 0.0 2.0 2.0 1.8 1.6 3.2 2.4 3.0 4.1 2.7 2.8 3.0 8.5 2.4 254.3 22.4 21.4 0.0 2.0 34.3 10.4 9.5 23.3 0.1 3.9 5.3 16.8 1.5 21.3 0.0 0.0 3.2 16.9 0.0 0.0 1.8 0.9 1.9 1.8 200.6 0.0 2.7 0.3 0.2 37.1 46.1 2.6 7.2 7.6 0.2 65.3 0.8 14.9 0.0 0.7 0.4 4.1 32.4 138.1 4.9 130.8 130.9 16.0 1.0 8.1 0.0 0.0 0.0 0.0 9.0 0.0 259.2 2.3 4.5 0.0 0.3 2.5 0.0 6.6 51.4 39.0 0.2 1.0 237.3 98.6 42.4 3.2 2.8 0.1 58.2 THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 47.1;Microglial cells: 15.0;T-cells: 59.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 4 "HDLM-2: 32.6;JURKAT: 54.1;MOLT-4: 51.6;RPMI-8226: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" 0.4 0.5 0.5 3.3 3.2 1.7 0.6 0.1 2.3 0.4 0.3 0.7 1.6 0.2 0.4 0.6 0.2 1.4 0.1 0.9 0.1 0.2 0.7 1.4 7.5 0.6 0.3 0.1 0.3 0.0 0.0 0.1 0.4 0.4 0.9 0.0 0.9 0.1 0.1 0.2 2.3 0.3 0.3 3.2 1.5 0.1 0.3 32.9 0.4 0.1 4.0 1.1 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 26.7 0.1 34.0 0.1 33.5 48.9 0.2 0.2 30.0 58.3 0.6 0.1 0.2 0.2 1.7 20.3 0.5 3.2 0.1 2.3 0.9 0.1 0.6 0.3 0.4 0.3 0.3 1.9 0.5 0.0 3.0 2.9 2.0 0.5 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.9 0.1 0.2 0.4 0.0 1.7 47.1 0.0 0.0 0.7 5.1 0.1 1.3 0.0 1.1 0.1 0.1 0.0 0.9 0.0 0.0 0.8 0.8 0.2 0.0 1.5 7.2 15.0 1.4 0.0 0.0 0.0 9.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.1 1.4 0.0 59.9 0.0 0.0 0.1 THEMIS2 "C1orf38, ICB-1" ENSG00000130775 "Thymocyte selection associated family member 2" Q5TEJ8 1 27872543-27886685 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 215.5;lymphoid tissue: 126.0" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Hofbauer cells: 62.6;Kupffer cells: 135.9;Langerhans cells: 59.9;Macrophages: 125.4;monocytes: 144.8;Plasma cells: 57.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 403.3;eosinophil: 341.0;intermediate monocyte: 441.4;myeloid DC: 309.6;neutrophil: 498.1;non-classical monocyte: 454.6;plasmacytoid DC: 125.2" "Group enriched" "Detected in all" 6 "dendritic cells: 309.6;granulocytes: 498.1;monocytes: 454.6" "Cell line enhanced" "Detected in many" "Karpas-707: 135.9;U-266/70: 98.4;U-937: 62.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027513, HPA031096" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA027513: , HPA031096: AB_10599254" "unprognostic (7.38e-2)" "unprognostic (6.56e-2)" "unprognostic (5.07e-2)" "unprognostic (1.99e-3)" "unprognostic (4.51e-2)" "unprognostic (5.56e-3)" "unprognostic (4.13e-1)" "unprognostic (8.21e-2)" "unprognostic (1.77e-2)" "unprognostic (3.05e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-2)" "unprognostic (7.21e-3)" "unprognostic (5.07e-2)" "unprognostic (1.42e-2)" "unprognostic (2.24e-3)" "unprognostic (4.52e-3)" 30.7 10.6 10.8 72.8 13.1 215.5 12.7 13.6 14.4 7.2 12.3 14.7 10.1 5.7 3.9 8.0 10.2 23.6 6.6 11.2 16.6 9.2 19.1 45.8 47.9 22.2 14.3 3.3 5.4 2.7 4.9 18.8 19.1 5.4 10.1 0.9 11.1 3.9 3.4 4.5 28.2 15.5 15.4 126.0 12.2 22.4 17.8 16.0 11.0 4.5 29.9 26.9 6.4 24.6 9.1 0.3 3.4 0.5 11.4 15.6 1.5 1.9 20.0 28.7 40.2 1.3 2.4 12.8 1.2 6.6 15.9 1.3 5.2 1.2 4.6 1.7 1.2 18.0 0.4 2.3 22.3 23.0 27.8 7.9 0.3 14.8 0.1 1.5 11.1 1.0 24.7 135.9 2.1 6.1 0.9 20.1 11.8 0.3 1.8 4.1 12.8 23.2 8.6 0.3 0.2 5.0 0.1 0.8 26.2 2.1 0.3 20.2 6.9 1.7 0.2 5.6 0.3 98.4 6.1 0.8 32.3 62.1 0.5 41.7 403.3 341.0 71.9 441.4 66.1 41.5 53.1 60.2 309.6 21.8 45.6 48.2 498.1 61.9 454.6 125.2 56.4 380.7 10.8 13.1 13.6 14.4 11.2 16.6 22.2 14.3 19.1 15.4 17.8 24.6 2.2 3.2 20.0 0.3 42.6 3.2 1.1 2.7 0.6 0.4 1.0 0.6 0.7 2.8 8.7 0.0 0.0 0.8 87.5 0.3 0.0 0.9 2.3 4.5 1.8 6.8 10.7 6.1 6.2 8.3 1.3 1.8 1.1 6.4 13.3 7.1 3.6 1.3 62.6 0.0 0.7 0.2 36.7 135.9 59.9 5.2 0.6 125.4 17.8 6.5 144.8 0.1 54.6 0.5 14.7 8.7 0.0 0.4 57.3 3.0 0.0 0.4 3.2 0.2 0.0 21.9 2.1 1.8 2.9 0.1 1.1 2.5 21.2 3.0 0.8 5.0 THRSP "Lpgp, LPGP1, S14, SPOT14, THRP" ENSG00000151365 "Thyroid hormone responsive" Q92748 11 78063861-78068351 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 210.0;liver: 408.9" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 128.4" "Cancer enhanced" "Detected in many" "liver cancer: 44.1" "Region enriched" "Detected in single" 6 "cerebellum: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "ASC diff: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040642 Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA040642: AB_10794878" "unprognostic (1.19e-1)" "unprognostic (2.88e-1)" "unprognostic (2.84e-1)" "unprognostic (2.73e-2)" "unprognostic (3.07e-1)" "unprognostic (9.91e-3)" "unprognostic (1.59e-2)" "unprognostic (9.60e-2)" "unprognostic (1.07e-2)" "unprognostic (8.23e-2)" "unprognostic (1.68e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (9.64e-2)" "unprognostic (1.57e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.69e-3)" 210.0 5.9 0.1 0.4 0.1 0.0 95.3 2.7 0.3 0.1 0.0 2.6 0.0 0.1 0.4 0.3 1.0 3.4 18.6 0.2 0.0 4.6 408.9 0.1 0.7 0.0 0.2 0.1 3.6 15.5 0.1 0.0 0.4 0.1 0.2 1.5 48.9 2.3 8.2 33.7 4.6 0.5 0.0 0.1 0.7 0.1 0.0 0.2 5.7 3.3 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.3 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 2.3 21.1 11.2 0.1 4.3 0.0 0.0 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.6 0.1 0.4 0.0 2.7 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.1 2.9 128.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.1 THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Bipolar cells: 183.8;Horizontal cells: 208.6;Inhibitory neurons: 494.3;Oligodendrocyte precursor cells: 262.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cell line enhanced" "Detected in some" "A549: 10.3;HUVEC TERT2: 6.7;REH: 7.1;SH-SY5Y: 10.2;THP-1: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" 2.4 0.7 2.9 0.7 2.3 0.0 2.1 3.2 4.4 3.3 0.0 1.0 0.3 2.8 0.8 0.5 2.1 2.6 0.7 4.2 3.5 7.5 0.6 1.1 0.3 2.8 4.9 2.5 0.4 1.2 1.6 4.1 2.5 3.4 0.7 5.0 0.5 2.1 0.2 0.5 0.5 2.4 3.4 0.9 0.5 0.8 4.8 0.2 1.9 1.2 0.2 1.8 1.7 2.4 0.0 10.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 7.1 0.0 0.0 0.3 0.1 0.7 10.2 0.0 0.3 0.0 1.6 0.1 19.2 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 3.2 4.4 4.2 3.5 2.8 4.9 2.5 3.4 4.8 2.4 46.9 22.4 8.2 150.5 0.0 2.7 1.4 0.0 1.2 183.8 0.8 0.5 1.5 21.5 2.8 55.2 112.6 23.5 0.1 0.4 7.9 7.0 1.2 4.9 22.4 42.6 41.7 0.0 56.6 2.2 4.3 8.1 0.5 18.8 0.0 6.1 28.2 1.3 2.2 208.6 494.3 0.8 0.0 1.5 2.9 0.5 24.2 0.5 12.4 105.9 0.0 20.7 0.0 262.4 5.4 5.5 6.8 1.5 0.1 7.7 0.1 8.8 0.1 9.3 0.0 10.6 5.0 1.6 1.1 0.6 2.4 51.9 0.8 21.5 1.2 1.1 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 38.7" "Group enriched" "Detected in some" 10 "dendritic cells: 64.2;NK-cells: 69.0;T-cells: 78.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 195.5" "Lineage enriched" "Detected in many" 11 "T-cells: 195.5" "Cell line enhanced" "Detected in single" "HDLM-2: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.24e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.22e-3)" "unprognostic (2.22e-6)" "unprognostic (9.84e-2)" "prognostic favorable (3.96e-4)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.50e-4)" "unprognostic (3.51e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.30e-8)" "unprognostic (3.54e-2)" "unprognostic (1.33e-1)" "unprognostic (7.62e-2)" "unprognostic (6.18e-3)" 0.7 0.3 0.3 12.1 0.5 2.1 0.7 0.6 0.5 0.8 0.2 2.1 1.7 0.9 0.7 2.1 0.5 3.6 0.7 0.4 0.4 0.4 2.9 2.9 38.7 0.8 0.5 0.5 0.2 0.1 0.2 0.3 0.7 1.4 2.4 0.3 1.8 0.2 0.1 1.0 5.2 0.9 0.4 15.0 3.7 0.8 0.7 9.0 0.9 0.0 20.4 5.1 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.5 0.0 0.2 0.1 0.0 0.4 0.2 0.1 29.8 0.2 3.5 1.4 48.5 90.3 0.2 0.9 5.2 39.8 0.7 17.3 0.2 1.0 195.5 22.0 0.3 0.5 0.6 0.5 0.4 0.4 0.8 0.5 0.7 0.4 0.7 0.9 0.9 0.0 3.3 0.0 3.7 3.1 0.1 0.0 0.6 0.4 0.4 0.6 0.6 0.0 1.3 0.0 2.1 0.1 64.2 0.0 0.0 0.0 0.0 0.2 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.9 2.6 0.4 1.3 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 1.8 4.2 0.3 0.0 2.3 3.6 0.0 0.9 0.1 69.0 0.0 0.1 0.0 0.0 0.0 6.9 0.2 0.0 0.1 0.0 0.6 0.0 1.0 0.5 0.7 3.0 0.2 3.3 0.0 78.4 0.0 0.2 0.0 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TIMP4 ENSG00000157150 "TIMP metallopeptidase inhibitor 4" Q99727 3 12153068-12158912 "Plasma proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 177.7;breast: 119.6" "Cell type enriched" "Detected in many" 10 "Adipocytes: 363.9" "Cancer enriched" "Detected in many" 13 "glioma: 66.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 212.9;ASC TERT1: 53.0;HSkMC: 91.9;NTERA-2: 50.7;U-87 MG: 53.6" "Region enhanced" "Detected in all" "cerebellum: 106.1" "Region enriched" "Detected in all" 9 "cerebellum: 47.7" "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.99e-2)" "unprognostic (5.14e-3)" "unprognostic (1.02e-2)" "unprognostic (2.10e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-4)" "unprognostic (9.33e-3)" "unprognostic (4.26e-3)" "unprognostic (1.36e-1)" "unprognostic (1.74e-2)" "unprognostic (3.78e-1)" "unprognostic (6.81e-2)" "unprognostic (4.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (6.66e-5)" "unprognostic (2.86e-1)" 177.7 8.3 7.7 3.9 8.4 0.6 119.6 49.6 7.2 9.3 3.9 12.1 1.4 8.1 1.0 2.9 6.8 4.4 31.0 6.8 8.8 2.8 1.1 6.6 0.6 13.7 8.6 3.8 4.0 1.4 12.3 9.9 11.7 5.5 4.3 1.0 8.9 2.3 16.7 7.7 11.0 4.4 11.3 3.4 9.2 0.7 7.1 2.0 23.1 30.1 0.1 9.8 8.7 11.6 0.7 24.2 0.7 0.0 212.9 53.0 26.4 0.8 8.9 1.0 1.3 0.5 0.1 0.0 2.2 0.9 0.8 0.9 0.0 0.8 0.4 1.0 0.0 0.0 12.7 0.9 33.2 0.0 0.1 91.9 2.2 5.8 0.2 1.6 0.0 0.0 0.5 17.3 0.2 0.6 0.0 0.0 50.7 0.0 6.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 5.0 0.0 0.0 6.1 0.0 0.0 1.0 0.1 0.0 0.6 0.9 0.0 0.1 0.0 53.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 8.4 49.6 7.2 6.8 8.8 13.7 8.6 11.7 11.3 7.1 11.6 363.9 0.0 0.0 0.0 0.4 0.1 1.3 0.3 0.6 0.4 12.4 2.8 7.0 0.0 0.2 0.0 0.0 0.4 1.4 1.3 0.0 0.6 1.6 0.2 2.1 33.6 6.6 5.3 0.1 2.6 2.7 15.7 0.0 0.0 0.0 0.2 22.5 0.0 3.4 0.0 0.2 2.8 0.0 1.2 0.3 7.5 12.2 0.8 3.6 0.0 0.0 0.7 0.0 9.0 0.1 4.6 4.8 2.6 0.0 4.2 2.7 0.5 5.5 0.0 32.9 3.1 29.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 2.0 2.2 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 TJP1 "DKFZp686M05161, MGC133289, ZO-1" ENSG00000104067 "Tight junction protein 1" Q07157 15 29699367-29968915 "Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 893.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001636, HPA001637, CAB010822" Enhanced Enhanced "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "CAB010822: , HPA001636: AB_1080762, HPA001637: AB_1080760" "unprognostic (2.11e-2)" "unprognostic (6.83e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-2)" "unprognostic (9.43e-2)" "unprognostic (1.21e-1)" "unprognostic (4.54e-2)" "unprognostic (6.71e-3)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.86e-3)" "unprognostic (3.54e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.85e-3)" "unprognostic (3.02e-1)" "unprognostic (5.04e-2)" "unprognostic (1.20e-1)" 37.4 16.5 22.1 4.4 35.3 1.1 30.8 21.4 24.4 33.2 17.9 30.5 7.1 42.3 16.5 60.4 27.8 12.6 37.1 22.0 22.2 24.3 18.6 34.0 5.7 26.6 28.6 22.3 30.0 13.4 16.8 31.6 25.2 20.4 9.5 10.0 29.6 10.9 22.0 27.8 19.8 17.4 20.6 13.5 25.8 29.7 30.3 3.7 24.8 5.0 10.2 23.8 35.3 42.6 62.4 36.8 29.1 18.4 17.0 31.7 28.9 18.6 21.1 18.0 20.2 59.2 22.9 0.3 24.8 24.6 21.3 47.4 20.1 23.8 19.0 0.5 14.9 0.3 22.3 24.7 57.9 0.1 0.8 16.5 15.8 21.4 39.2 23.0 38.2 0.1 24.3 12.5 14.2 32.2 0.2 0.7 21.9 23.4 14.6 0.1 35.0 0.2 28.1 33.4 12.9 16.8 39.2 12.8 16.8 42.9 13.3 0.6 54.7 14.3 23.9 12.5 25.6 4.4 4.6 0.4 17.8 0.3 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 35.3 21.4 24.4 22.0 22.2 26.6 28.6 25.2 20.6 30.3 42.6 212.1 169.9 49.2 299.7 1.6 35.8 115.2 36.4 39.3 42.4 53.7 28.6 107.2 51.5 48.6 58.8 10.4 32.3 0.8 87.7 25.4 116.0 19.1 132.2 97.0 166.0 46.0 2.7 293.8 83.7 11.3 56.6 86.6 290.7 5.7 87.7 100.3 49.1 3.8 126.2 187.3 45.4 32.6 6.1 12.1 13.7 33.8 5.2 64.0 266.1 1.6 32.8 0.0 345.3 893.8 178.3 82.0 63.9 5.9 151.4 37.8 26.0 39.2 52.4 78.9 64.1 118.7 63.0 83.9 139.2 60.1 33.7 4.1 120.8 33.1 194.6 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 237.5" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 44.4 14.9 35.1 11.6 45.3 12.0 30.2 44.5 42.6 16.9 25.7 39.0 54.4 19.8 13.1 45.8 23.8 24.4 35.8 38.0 45.4 44.7 64.8 47.6 9.7 52.6 39.9 37.0 21.9 57.9 5.3 18.4 52.6 24.8 35.1 122.0 37.1 21.9 14.1 35.0 49.6 16.1 55.0 5.7 58.3 32.1 39.9 32.5 44.9 15.1 23.1 55.3 22.3 66.3 237.5 6.4 24.4 25.8 92.9 90.3 108.5 37.3 26.7 54.9 29.0 31.8 106.6 33.0 37.0 20.3 31.4 158.3 33.2 79.3 75.9 115.3 20.7 34.5 22.5 165.2 28.9 13.8 59.1 71.3 65.2 43.1 32.4 19.6 143.6 9.9 19.7 24.7 34.3 36.0 5.5 2.3 49.5 194.5 50.0 23.1 26.9 2.9 192.0 194.2 8.3 14.9 13.3 111.2 3.4 55.7 37.0 7.9 196.3 44.3 48.3 32.4 38.6 23.0 5.2 0.9 48.0 19.6 16.1 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.8 0.1 35.1 45.3 44.5 42.6 38.0 45.4 52.6 39.9 52.6 55.0 39.9 66.3 2.9 44.8 22.8 76.4 2.3 65.1 79.1 26.3 4.6 212.4 4.6 1.3 38.5 40.0 33.1 3.7 35.5 27.9 2.7 74.4 0.0 32.5 3.5 7.1 1.7 36.4 11.5 10.5 10.1 24.3 25.6 15.5 64.2 9.9 5.7 0.2 27.5 104.9 5.6 18.5 13.4 45.0 36.7 14.6 28.9 6.7 29.2 8.2 28.4 22.5 9.0 111.1 1.0 21.6 82.5 44.2 65.8 13.9 5.2 115.4 73.4 1.9 51.3 267.6 0.0 4.9 13.1 19.6 18.0 40.6 64.1 43.2 3.2 0.2 50.3 244.5 TJP3 ZO-3 ENSG00000105289 "Tight junction protein 3" O95049 19 3708362-3750813 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.0;stomach 1: 27.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 238.7;Early spermatids: 405.1;Paneth cells: 140.4;Proximal enterocytes: 130.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 1.2;MAIT T-cell: 3.9;memory CD4 T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD4 T-cell: 3.3;naive CD8 T-cell: 1.2;T-reg: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.9" "Cell line enhanced" "Detected in some" "BEWO: 44.0;CAPAN-2: 41.1;MCF7: 20.3;OE19: 37.4;SK-BR-3: 25.7;T-47d: 52.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB013244, HPA046863, HPA053337" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" "CAB013244: AB_2533257, HPA046863: AB_2679845, HPA053337: AB_2682118" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.83e-6)" "unprognostic (2.78e-1)" "prognostic favorable (9.52e-4)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-1)" "unprognostic (6.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.78e-1)" "prognostic favorable (9.36e-8)" "unprognostic (8.58e-3)" "unprognostic (5.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.62e-3)" 0.2 0.0 0.2 4.7 0.1 0.1 4.0 0.1 0.4 6.3 7.4 34.1 43.0 1.5 2.4 25.5 13.7 6.2 0.0 0.4 0.1 5.8 7.1 5.2 0.4 0.2 0.4 0.1 6.4 7.5 1.7 1.6 0.2 4.0 13.2 0.1 20.8 5.3 0.7 7.3 37.4 0.5 0.0 0.5 27.0 2.5 0.0 0.2 6.9 0.0 2.6 4.1 6.0 0.3 0.3 8.3 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.0 13.0 41.1 8.2 1.3 0.0 0.1 10.4 0.6 0.0 0.0 0.5 0.2 0.0 0.7 2.9 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.3 0.0 20.3 0.0 0.3 0.9 37.4 0.2 0.1 0.0 6.2 1.4 6.8 0.2 0.2 1.6 25.7 0.0 3.3 52.2 0.2 0.0 0.1 1.0 0.1 0.0 1.7 2.5 0.1 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.0 3.9 0.4 3.1 2.4 0.0 0.6 3.3 1.2 0.0 0.0 0.0 0.0 3.8 1.2 0.2 0.1 0.1 0.4 0.4 0.1 0.2 0.4 0.2 0.0 0.0 0.3 0.1 9.6 13.7 0.3 1.9 0.0 7.0 21.0 0.0 0.0 20.3 6.3 0.9 34.3 42.1 31.3 0.0 32.1 0.8 238.7 19.6 21.1 405.1 31.2 1.1 0.5 12.5 0.0 0.9 23.6 4.2 0.6 52.5 13.2 4.5 0.1 0.0 7.3 2.7 0.0 0.9 50.9 24.4 0.3 0.3 36.5 1.8 0.8 3.6 0.0 0.1 0.0 0.0 0.5 1.4 21.8 140.4 1.2 0.2 6.5 130.4 8.0 86.1 0.0 0.0 0.0 3.4 4.3 4.8 8.0 0.1 40.2 4.3 0.0 62.1 25.6 TK2 SCA31 ENSG00000166548 "Thymidine kinase 2" O00142 16 66508003-66552544 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041162 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041162: AB_10961178" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (6.27e-3)" "unprognostic (3.94e-1)" "unprognostic (2.93e-1)" "unprognostic (1.10e-1)" "unprognostic (4.83e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-1)" "unprognostic (3.59e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.18e-6)" "unprognostic (3.05e-2)" "unprognostic (1.74e-1)" "unprognostic (2.71e-1)" "unprognostic (7.05e-2)" 48.1 30.2 24.2 11.8 27.6 8.5 25.6 24.7 25.7 20.0 19.7 15.0 10.9 16.2 29.3 12.3 19.0 21.1 19.2 24.1 25.6 25.1 37.3 18.7 11.7 26.5 27.8 26.8 24.4 38.0 22.4 15.1 27.6 19.2 12.7 11.7 22.6 19.9 11.5 12.7 13.5 18.9 27.5 23.0 15.7 33.9 25.8 13.0 25.6 14.6 9.9 17.8 15.4 28.3 13.3 26.5 12.1 14.5 64.3 52.2 0.7 22.0 22.3 15.1 16.8 6.5 26.4 0.1 23.8 63.9 19.0 11.8 5.3 17.7 10.4 8.5 6.2 4.1 17.2 12.9 45.1 5.6 9.2 39.4 15.3 18.5 26.1 62.5 19.9 13.1 6.8 28.1 37.9 4.1 5.5 14.9 5.9 5.1 15.4 7.0 21.0 28.1 44.1 12.5 4.4 8.9 63.2 6.1 26.9 6.6 9.6 16.3 29.7 30.8 15.9 26.3 7.6 30.3 12.2 11.6 38.9 5.7 18.4 5.6 9.4 6.0 1.8 5.1 1.2 0.1 1.3 1.0 8.7 1.7 0.6 0.9 8.5 2.7 4.3 1.8 1.2 2.5 24.2 27.6 24.7 25.7 24.1 25.6 26.5 27.8 27.6 27.5 25.8 28.3 25.0 22.4 9.3 19.6 7.3 5.7 5.1 5.8 12.5 15.5 15.4 11.4 8.0 17.2 7.5 22.0 22.9 10.0 7.6 6.0 9.8 15.7 25.2 15.2 23.2 14.4 9.6 10.3 10.1 22.4 6.0 19.9 11.7 13.0 24.8 20.6 31.1 48.9 21.7 21.9 12.0 6.5 2.0 55.6 10.1 40.5 23.3 23.6 10.6 10.3 22.6 18.4 12.3 14.6 19.4 28.9 3.3 19.2 12.4 4.3 14.4 45.9 9.0 20.5 0.0 14.4 10.6 48.9 11.1 9.6 3.8 2.9 8.6 22.2 7.6 4.2 TKT ENSG00000163931 Transketolase P29401 3 53224712-53256052 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 667.0" "Cell type enhanced" "Detected in all" "Kupffer cells: 696.7;monocytes: 624.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 447.9;eosinophil: 274.4;intermediate monocyte: 199.0;myeloid DC: 203.8;neutrophil: 375.3;non-classical monocyte: 242.6" "Group enriched" "Detected in all" 9 "dendritic cells: 203.8;granulocytes: 375.3;monocytes: 447.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced Nucleoplasm NA NA 150000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA029480: AB_10599307, HPA029481: AB_10601895" "unprognostic (5.05e-2)" "unprognostic (3.34e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (7.21e-6)" "unprognostic (6.78e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-2)" "unprognostic (3.06e-3)" "unprognostic (1.36e-2)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.07e-1)" "unprognostic (3.29e-1)" "unprognostic (9.90e-3)" 152.2 93.2 78.0 66.2 80.0 667.0 71.9 93.2 82.3 59.7 60.5 73.2 84.2 44.7 19.2 168.5 53.7 97.2 27.4 72.3 96.9 68.2 58.1 93.4 69.2 89.2 89.9 87.7 154.0 41.4 45.6 61.2 93.8 48.8 48.8 21.7 54.9 50.9 12.8 47.0 58.1 51.6 77.4 99.8 66.1 20.2 87.9 82.9 116.1 15.2 67.4 130.9 85.5 97.2 313.0 1542.9 216.0 241.5 470.8 570.8 439.5 206.2 353.8 348.8 330.8 430.1 779.3 388.5 96.8 302.9 673.3 438.3 377.9 775.8 102.4 131.0 210.3 259.6 1022.2 655.2 573.9 321.4 168.1 416.0 437.5 418.5 213.7 949.2 444.9 323.8 188.3 164.7 144.5 381.6 338.6 358.1 737.1 603.0 367.9 201.1 98.5 726.2 550.3 520.2 139.6 103.7 383.4 605.3 365.1 656.7 188.8 437.4 335.9 107.2 164.2 320.0 401.9 94.5 190.3 235.7 234.4 321.0 203.8 51.5 447.9 274.4 17.8 199.0 22.8 39.7 25.8 20.6 203.8 21.1 26.6 20.7 375.3 30.8 242.6 34.4 36.7 312.4 78.0 80.0 93.2 82.3 72.3 96.9 89.2 89.9 93.8 77.4 87.9 97.2 79.5 134.6 125.6 46.7 92.1 79.4 384.6 325.3 287.4 41.0 99.3 80.5 14.9 75.8 149.5 62.5 29.2 349.0 69.7 139.1 80.3 197.7 6.5 87.4 79.6 81.8 52.6 150.3 16.9 269.8 249.8 80.2 168.7 95.5 62.7 123.6 75.0 83.4 256.0 37.0 23.9 149.6 142.4 696.7 110.5 8.9 157.2 333.3 76.5 17.8 624.4 88.8 46.4 17.1 39.3 193.6 81.4 106.8 109.4 337.7 141.5 219.1 99.2 46.3 52.6 35.9 102.1 16.8 30.6 409.3 67.1 413.6 78.8 427.2 276.7 413.6 TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 112.4;Proximal enterocytes: 68.9;Skeletal myocytes: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 3.4;neutrophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.0;HaCaT: 8.4;SiHa: 11.2;T-47d: 9.4" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 14.2" HPA046063 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" 10.3 9.4 0.6 1.8 0.7 2.1 4.7 1.6 0.9 3.0 2.3 7.3 6.0 1.8 1.2 4.7 2.7 1.8 2.1 0.6 0.5 1.8 7.0 3.9 0.7 1.0 0.7 2.5 1.2 1.0 1.1 1.5 1.0 1.9 5.3 10.5 2.9 0.9 1.7 2.4 6.9 1.2 0.7 1.3 4.7 0.6 1.0 0.1 1.6 0.8 0.8 3.1 3.5 1.6 1.0 1.1 1.1 3.5 8.1 9.0 0.3 1.9 1.8 1.0 0.7 6.9 3.1 0.1 1.9 3.1 1.0 8.4 1.5 0.9 0.7 0.2 0.7 0.9 2.4 0.3 2.3 0.1 2.4 7.6 3.2 1.2 2.2 2.9 0.7 0.1 0.8 0.4 0.9 1.9 0.1 0.4 0.1 3.4 0.6 0.1 5.3 0.2 0.7 2.7 0.2 0.4 11.2 1.0 1.6 1.5 9.4 0.8 2.6 0.5 2.3 2.1 0.5 0.1 0.1 0.1 0.6 0.3 1.0 3.4 0.2 0.4 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.4 0.2 0.2 1.6 0.3 0.1 0.2 0.1 0.1 0.6 0.7 1.6 0.9 0.6 0.5 1.0 0.7 1.0 0.7 1.0 1.6 19.0 51.3 55.5 0.3 1.6 0.0 8.2 0.0 4.0 7.9 5.8 9.5 2.7 17.2 18.0 11.0 129.3 4.9 2.0 112.4 0.0 7.3 1.1 12.9 10.4 14.1 9.0 11.2 0.5 9.6 2.6 14.9 20.9 13.3 15.8 3.9 18.9 24.2 5.5 0.0 0.4 24.6 0.0 6.5 0.0 1.8 13.4 10.7 0.0 3.7 1.4 11.7 0.0 0.0 0.1 13.5 40.1 5.7 3.3 6.3 68.9 1.1 19.9 57.8 6.6 124.2 17.8 0.6 0.8 9.1 0.3 4.0 5.1 5.4 35.7 13.0 TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.0" "Cell type enhanced" "Detected in all" "Early spermatids: 818.9;Late spermatids: 1315.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 99.9;BJ hTERT+: 98.7;BJ hTERT+ SV40 Large T+: 89.4;fHDF/TERT166: 154.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065357 Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA065357: AB_2685479" "unprognostic (6.68e-2)" "unprognostic (8.50e-3)" "unprognostic (2.13e-3)" "unprognostic (2.92e-1)" "unprognostic (1.91e-1)" "unprognostic (9.79e-2)" "unprognostic (1.24e-2)" "unprognostic (4.83e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (9.94e-3)" "unprognostic (1.04e-1)" "prognostic favorable (6.94e-4)" "unprognostic (1.49e-1)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" 9.3 15.7 18.4 16.4 45.2 67.9 8.7 22.3 27.4 9.6 20.2 9.9 8.4 14.3 5.9 17.6 12.9 16.6 8.0 27.5 21.6 6.9 5.6 12.5 15.9 31.7 21.4 32.3 6.4 10.6 24.2 19.7 32.2 5.6 10.5 24.7 10.9 8.4 23.1 18.9 11.3 14.5 26.1 18.5 14.1 108.0 25.4 27.8 10.4 10.3 19.9 18.7 12.8 64.0 0.0 19.0 70.7 0.5 11.4 9.6 21.2 99.9 98.7 89.4 34.4 2.8 10.3 7.4 0.2 154.3 13.7 20.8 5.0 18.3 39.2 38.2 30.8 0.0 9.1 0.4 13.8 21.4 13.0 11.3 12.6 26.1 5.2 25.2 23.9 14.0 1.5 21.3 28.6 0.7 29.4 9.4 22.5 11.9 4.8 25.7 35.9 7.4 5.5 2.7 28.5 41.5 14.7 1.9 0.1 32.8 0.0 25.1 36.4 34.8 0.1 0.8 5.0 14.4 25.0 10.9 12.3 18.0 16.6 24.2 4.4 17.1 4.8 6.3 5.9 1.3 2.5 3.6 2.9 1.7 1.5 2.5 11.7 3.2 4.9 1.0 0.8 2.6 18.4 45.2 22.3 27.4 27.5 21.6 31.7 21.4 32.2 26.1 25.4 64.0 108.9 6.4 19.4 77.4 91.9 121.0 57.2 50.6 167.4 76.8 76.0 92.8 15.9 84.4 45.6 14.7 127.2 77.2 228.1 163.5 3.9 13.4 818.9 262.0 230.0 59.7 25.2 22.3 150.8 22.0 67.1 71.4 137.1 158.7 21.0 34.8 53.2 14.1 51.1 218.7 33.3 117.3 61.1 167.9 70.4 1315.5 105.6 101.7 42.7 77.8 75.3 31.0 88.6 301.6 381.0 31.7 207.6 46.6 152.7 37.8 122.0 18.1 50.4 290.2 72.3 280.7 83.9 38.3 146.0 140.0 90.8 65.0 141.0 86.8 96.0 99.9 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TLN2 "ILWEQ, KIAA0320" ENSG00000171914 "Talin 2" Q9Y4G6 15 62390526-62844631 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 38.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.7;Inhibitory neurons: 127.2;Microglial cells: 139.6;Oligodendrocyte precursor cells: 108.6;Oligodendrocytes: 93.6;Skeletal myocytes: 135.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 59.3;hTERT-HME1: 48.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017194, HPA051828, HPA054787" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 46000000 "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites, Cytosol" "CAB017194: , HPA051828: AB_2732570, HPA054787: AB_2732587" "prognostic favorable (6.53e-4)" "unprognostic (2.61e-1)" "unprognostic (9.47e-2)" "unprognostic (8.95e-2)" "unprognostic (3.74e-1)" "unprognostic (1.43e-1)" "unprognostic (8.24e-2)" "unprognostic (9.94e-2)" "unprognostic (1.68e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (1.91e-1)" "prognostic favorable (1.81e-6)" "prognostic favorable (7.74e-4)" "unprognostic (1.34e-1)" "unprognostic (5.79e-2)" "unprognostic (2.30e-1)" 19.0 4.1 14.2 2.2 15.6 3.8 10.4 3.2 16.9 8.0 20.2 9.3 4.7 3.7 2.1 2.1 4.3 1.9 12.1 18.3 8.2 38.4 4.8 2.4 0.5 7.6 8.2 4.6 4.7 2.4 5.5 1.2 6.2 2.3 7.3 7.7 7.8 2.1 26.1 3.6 5.1 2.9 11.2 1.3 5.5 5.4 7.0 3.1 13.0 12.2 0.5 4.1 4.2 13.8 1.8 5.6 8.0 9.4 59.3 5.6 9.0 13.7 10.8 12.4 12.2 15.1 1.9 4.8 6.2 24.0 20.5 2.4 10.3 2.2 10.8 15.2 1.0 0.6 22.8 10.1 2.0 1.6 0.4 10.3 5.6 16.6 48.9 7.1 0.5 5.7 0.6 0.2 21.0 7.5 0.7 0.6 14.2 26.3 4.1 5.8 20.3 5.8 6.5 11.6 1.9 9.3 10.6 1.1 3.5 17.1 2.9 3.6 3.9 22.2 30.0 36.3 35.6 0.3 0.9 3.1 10.1 3.4 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 15.6 3.2 16.9 18.3 8.2 7.6 8.2 6.2 11.2 7.0 13.8 11.5 0.0 3.2 50.6 1.1 2.4 1.8 0.7 1.2 18.6 16.5 10.2 41.1 5.7 0.9 27.6 37.5 1.2 0.7 39.0 11.7 3.5 4.3 10.9 14.3 9.0 2.4 37.7 153.7 3.9 29.7 21.5 40.8 17.4 0.0 9.3 3.3 12.6 4.9 48.8 127.2 20.0 6.1 6.2 3.1 5.2 11.8 5.5 0.0 139.6 0.8 11.1 1.0 108.6 93.6 3.7 21.0 15.8 0.7 1.5 14.6 35.1 0.1 48.3 0.0 135.6 12.3 6.7 24.5 3.1 1.6 1.4 1.3 25.8 37.7 1.7 TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 49.8;Macrophages: 21.1;monocytes: 39.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" 3.6 0.5 0.2 16.8 0.2 5.7 0.9 0.2 0.3 0.7 0.5 1.7 0.8 0.4 0.1 0.9 0.6 2.5 0.8 0.1 0.3 0.5 2.2 10.7 6.1 1.1 0.7 0.4 0.6 0.3 0.1 4.3 0.8 0.3 1.8 0.0 0.3 0.2 0.2 0.2 1.5 3.8 0.5 13.3 0.8 0.4 0.4 1.7 0.4 1.3 1.9 3.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 14.9 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.0 27.6 0.0 15.6 0.0 0.0 3.8 0.2 0.2 0.2 0.3 0.1 0.3 1.1 0.7 0.8 0.5 0.4 0.9 0.0 0.0 3.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.7 5.3 0.0 0.0 0.0 0.0 49.8 5.1 0.0 0.0 21.1 0.0 0.0 39.7 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 47.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;granulocytes: 44.4;Hofbauer cells: 50.9;Kupffer cells: 37.8;Langerhans cells: 46.4;Macrophages: 45.9;Microglial cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 76.6;eosinophil: 195.8;neutrophil: 118.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 195.8" "Cell line enhanced" "Detected in some" "HEL: 23.2;HHSteC: 49.6;HUVEC TERT2: 27.7;JURKAT: 36.4;TIME: 68.3;U-698: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "HPA016051: AB_2203924, HPA056857: AB_2683259" "unprognostic (8.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-2)" "unprognostic (4.67e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.15e-2)" "unprognostic (4.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" 6.5 3.9 5.4 5.2 6.0 5.3 4.6 7.7 8.8 3.3 6.3 2.6 2.0 2.8 2.1 3.1 2.8 3.7 9.6 5.2 5.6 1.9 2.3 10.7 5.7 6.8 6.0 1.7 1.2 1.8 0.9 7.8 6.6 2.1 2.6 2.8 2.9 1.3 47.3 1.8 2.6 3.9 6.9 6.2 2.1 3.6 5.4 2.2 10.4 21.8 3.0 3.8 1.5 7.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.3 5.6 0.0 0.2 0.0 0.3 0.1 1.0 0.0 0.3 0.0 3.7 0.0 0.0 0.0 0.3 23.2 0.0 0.0 49.6 1.6 0.1 0.2 0.0 0.0 0.1 0.3 27.7 36.4 0.9 0.0 0.4 0.0 0.0 3.0 0.6 0.0 0.0 0.0 4.2 0.0 0.1 0.4 1.2 0.3 0.2 0.0 1.9 0.5 0.0 14.9 68.3 0.6 0.9 0.1 0.3 2.1 0.0 17.0 0.1 3.4 0.1 76.6 31.7 195.8 5.0 13.4 0.0 0.3 0.5 0.8 18.9 0.9 0.1 0.8 118.1 5.0 6.4 2.6 0.0 11.8 5.4 6.0 7.7 8.8 5.2 5.6 6.8 6.0 6.6 6.9 5.4 7.6 30.5 0.0 6.0 2.9 0.9 2.4 0.1 0.4 0.6 1.6 0.5 1.8 1.2 1.5 0.8 0.0 0.0 0.3 7.5 0.0 0.0 0.2 13.1 0.6 0.2 16.7 0.0 4.4 18.7 2.0 0.4 1.5 0.0 0.3 44.4 0.0 7.9 0.1 50.9 0.0 22.4 0.0 0.0 37.8 46.4 7.4 0.9 45.9 3.6 46.9 19.4 0.5 16.5 2.0 1.9 0.4 0.0 0.0 0.7 0.1 0.0 0.0 1.4 1.3 0.0 1.4 0.6 13.1 7.5 0.1 1.7 0.3 4.2 0.1 0.0 0.1 TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 246.0" "Cell type enhanced" "Detected in all" "Granulosa cells: 482.7;Hepatocytes: 220.6;Muller glia cells: 204.7;Theca cells: 204.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 69.2;RPTEC TERT1: 86.2;T-47d: 143.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" 63.4 246.0 27.8 2.6 28.5 4.1 29.1 32.8 33.9 17.4 64.1 7.8 9.4 3.4 17.0 39.6 12.8 7.0 47.3 30.0 29.7 18.9 86.4 10.1 3.4 34.0 32.0 36.5 69.9 36.3 19.5 3.9 32.5 41.1 3.9 6.0 46.9 6.0 7.1 68.2 8.3 1.9 30.1 5.1 35.6 11.5 32.6 5.6 15.5 3.7 8.4 5.5 22.1 35.1 7.7 10.9 27.3 35.1 8.1 1.3 15.4 1.8 4.5 2.7 3.0 26.0 35.8 16.3 26.9 2.2 1.0 13.3 11.6 21.2 1.9 16.7 5.0 10.2 2.7 54.5 18.8 4.2 10.6 3.7 5.0 14.6 3.9 12.6 3.9 28.7 5.8 13.9 0.8 69.2 8.3 18.6 12.6 18.4 11.2 22.4 1.2 39.9 86.2 12.6 27.2 30.5 1.2 28.2 6.1 19.5 143.9 11.4 3.1 0.4 3.4 3.8 2.3 27.1 18.1 8.4 2.5 5.9 1.0 1.1 1.6 3.4 9.1 1.5 7.0 12.4 5.6 7.8 1.5 11.9 11.8 9.0 1.1 12.5 0.9 38.1 5.6 4.9 27.8 28.5 32.8 33.9 30.0 29.7 34.0 32.0 32.5 30.1 32.6 35.1 4.0 9.6 43.7 23.5 12.7 1.9 6.2 33.6 5.7 19.2 52.2 38.5 99.4 52.9 36.6 44.1 10.4 72.9 16.3 23.3 17.6 27.1 28.8 17.9 2.6 5.7 59.4 13.7 11.6 27.7 4.6 4.3 31.1 16.5 7.0 482.7 5.0 220.6 15.6 25.2 15.3 21.8 52.9 6.3 2.7 59.3 9.9 5.8 12.4 2.8 9.4 204.7 7.2 17.1 36.5 21.7 23.7 2.2 12.9 31.3 29.0 77.5 37.9 23.6 13.1 1.6 21.8 13.3 17.9 18.0 7.0 82.1 8.3 204.8 19.0 10.4 TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 281.2;Pancreatic endocrine cells: 294.3;Syncytiotrophoblasts: 282.1;Urothelial cells: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 573.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" 231.0 120.9 118.0 84.1 135.0 96.1 165.5 124.8 123.6 146.8 112.1 143.1 152.6 119.7 92.9 333.4 97.3 135.5 123.3 109.4 131.2 123.5 170.8 175.1 55.4 194.5 144.0 93.5 240.3 125.6 50.2 172.7 150.7 97.6 140.7 15.2 155.1 89.5 219.1 185.3 174.6 127.1 139.8 65.9 212.3 25.4 134.1 41.9 158.0 185.2 106.8 172.9 215.1 144.2 183.9 66.4 3.5 47.1 404.3 170.6 188.7 175.5 217.9 103.4 117.7 169.8 449.0 40.6 123.3 263.0 194.6 305.3 59.8 399.9 100.4 151.0 23.5 264.6 41.8 205.6 183.3 2.4 252.4 161.1 370.7 210.4 265.6 108.4 111.8 6.7 169.0 75.0 182.9 6.1 2.8 46.5 2.5 382.3 60.4 5.7 28.3 33.1 142.1 573.4 2.2 3.1 58.0 214.7 122.8 36.6 56.3 39.8 168.4 182.4 50.1 84.9 64.8 35.9 45.2 17.7 179.9 41.0 105.5 352.9 136.4 298.5 107.9 172.7 91.8 77.1 98.0 89.1 93.3 61.9 64.3 70.2 167.1 66.7 221.9 25.9 116.1 190.1 118.0 135.0 124.8 123.6 109.4 131.2 194.5 144.0 150.7 139.8 134.1 144.2 47.6 73.7 25.6 20.9 37.2 81.7 96.9 85.0 51.2 2.0 28.8 26.0 26.4 78.6 66.9 69.9 0.0 139.1 51.8 266.8 13.7 175.5 0.6 45.6 42.6 50.8 22.7 66.3 2.4 281.2 146.8 61.9 110.6 78.4 50.0 16.1 28.9 50.4 104.9 0.0 2.5 67.9 52.9 45.1 50.2 2.8 54.0 69.6 46.2 14.0 22.0 22.9 48.4 5.0 35.2 294.3 177.3 59.5 30.3 151.8 204.4 37.7 34.8 1.9 13.1 35.7 45.0 1.4 12.5 86.5 101.2 282.1 41.3 9.9 69.1 299.8 TMC5 FLJ13593 ENSG00000103534 "Transmembrane channel like 5" Q6UXY8 16 19410496-19499113 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.4;stomach 1: 46.0" "Cell type enhanced" "Detected in many" "Club cells: 282.4;Pancreatic endocrine cells: 302.2;Proximal enterocytes: 374.3;Respiratory ciliated cells: 624.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 69.7;OE19: 41.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040810, HPA042037" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA040810: AB_10795627, HPA042037: AB_10804126" "unprognostic (2.47e-2)" "unprognostic (3.68e-1)" "unprognostic (3.50e-2)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (3.64e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "unprognostic (9.74e-2)" "unprognostic (3.27e-2)" "unprognostic (3.71e-1)" "unprognostic (2.28e-2)" "unprognostic (2.69e-1)" "unprognostic (7.88e-2)" "unprognostic (8.88e-3)" "unprognostic (1.75e-1)" 0.6 0.1 0.2 3.1 0.4 1.5 12.7 0.5 0.3 8.9 5.6 21.6 45.4 2.1 17.5 1.2 5.1 25.5 0.1 0.3 0.0 0.3 0.6 18.9 0.2 0.2 0.2 0.1 2.3 6.0 0.1 3.2 0.2 12.2 22.7 0.2 22.8 0.2 0.1 1.8 53.4 1.1 0.0 0.1 46.0 3.8 0.2 0.1 0.7 0.0 1.1 3.2 0.5 0.2 6.9 10.8 0.0 0.3 0.0 0.0 9.7 0.1 0.0 0.0 0.0 0.1 69.7 0.0 0.3 0.0 0.2 4.4 1.1 0.0 0.0 0.1 0.1 0.0 1.8 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 1.1 0.0 0.2 2.5 41.5 3.1 0.0 0.0 2.6 0.1 0.3 0.7 0.2 0.1 2.1 0.0 1.1 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.3 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.1 157.0 162.5 0.0 1.8 0.8 22.9 46.6 2.8 0.3 57.4 17.9 0.9 102.9 282.4 22.0 2.1 39.0 1.0 173.7 0.0 121.1 32.8 107.0 6.9 2.9 38.9 8.0 1.9 166.3 3.4 3.3 188.1 88.4 5.7 11.0 0.7 0.6 2.7 3.3 2.0 101.5 26.4 0.0 1.1 32.6 0.3 1.8 1.8 0.0 1.0 0.2 0.0 0.5 0.9 302.2 180.9 0.7 0.5 103.1 374.3 2.0 624.7 1.9 0.0 0.4 9.5 1.3 1.1 2.2 1.7 16.3 1.3 1.5 125.1 55.9 TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 9.6" "Group enriched" "Detected in many" 6 "Early spermatids: 172.0;Late spermatids: 44.6;Oligodendrocytes: 96.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA029465: AB_10600914" "unprognostic (1.80e-4)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.25e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-5)" "prognostic unfavorable (3.20e-4)" "unprognostic (7.60e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.39e-1)" "unprognostic (1.00e-1)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "prognostic favorable (9.20e-4)" 2.1 0.2 6.0 1.0 15.8 0.3 1.7 12.4 10.6 0.5 0.4 3.8 2.5 0.7 0.6 0.4 0.4 1.4 1.4 7.0 9.0 0.6 0.3 2.9 0.3 13.8 13.2 0.2 0.4 0.4 0.3 4.3 12.6 1.5 4.5 1.1 0.4 0.9 0.9 1.1 2.7 1.1 7.5 0.6 3.1 9.6 15.0 0.2 0.8 0.9 0.2 8.1 0.8 23.9 1.9 3.5 1.0 1.9 0.2 1.6 4.8 0.6 1.0 0.7 1.5 1.2 8.5 0.2 7.9 0.7 1.8 6.8 2.9 2.8 0.9 0.1 2.0 0.1 3.6 5.5 0.2 0.2 0.1 0.3 4.1 6.5 7.2 2.2 2.6 3.8 2.2 0.2 2.8 3.9 0.3 0.3 3.1 11.1 5.1 0.2 3.1 0.2 1.3 8.7 0.6 1.9 2.1 5.4 0.6 4.9 1.7 0.6 2.3 1.1 1.8 1.3 3.3 0.4 0.9 0.2 5.4 0.3 1.0 0.7 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.0 6.0 15.8 12.4 10.6 7.0 9.0 13.8 13.2 12.6 7.5 15.0 23.9 12.6 3.2 6.2 3.9 0.1 0.4 4.4 3.2 0.0 0.6 1.3 0.4 0.7 1.5 2.0 0.0 0.0 0.2 0.0 13.4 0.0 4.1 172.0 1.4 0.4 4.9 1.2 2.7 7.5 11.0 2.3 0.6 9.2 2.4 0.0 1.2 4.6 0.2 0.2 0.0 12.1 6.0 4.1 0.0 1.2 44.6 1.2 0.6 0.0 6.5 0.2 0.3 2.1 6.6 96.5 14.0 8.0 0.4 0.1 2.3 3.6 0.3 0.9 2.7 0.0 1.6 2.2 6.9 12.1 1.9 1.0 0.3 0.4 0.1 7.6 17.3 TMC8 "EVER2, EVIN2" ENSG00000167895 "Transmembrane channel like 8" Q8IU68 17 78130770-78142968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;intestine: 54.6;lymphoid tissue: 117.0" "Cell type enhanced" "Detected in many" "B-cells: 44.9;dendritic cells: 52.3;granulocytes: 41.2;Langerhans cells: 44.6;NK-cells: 85.5;T-cells: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 46.3;HL-60: 63.0;HMC-1: 119.9;Karpas-707: 103.9;RPMI-8226: 66.6;U-266/70: 49.3;U-937: 51.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047387, HPA054429" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA047387: , HPA054429: AB_2682485" "unprognostic (8.54e-3)" "prognostic favorable (8.45e-6)" "unprognostic (1.32e-1)" "unprognostic (2.33e-3)" "unprognostic (3.59e-1)" "prognostic favorable (4.19e-5)" "unprognostic (6.38e-3)" "unprognostic (6.47e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (6.06e-2)" "unprognostic (4.27e-1)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.24e-2)" "unprognostic (1.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" 7.8 3.0 3.6 56.0 4.4 91.8 3.7 3.7 5.1 3.7 3.5 8.2 10.3 2.5 0.7 4.8 4.0 7.4 2.7 3.6 4.8 5.2 7.1 18.4 100.5 5.8 4.7 1.3 2.0 0.5 2.2 3.9 5.6 4.9 4.5 0.1 5.8 1.3 1.8 3.6 54.6 2.4 5.0 117.0 10.4 1.2 7.8 60.1 6.4 0.9 46.7 6.4 5.0 7.2 0.5 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.3 46.3 2.0 0.0 0.1 3.4 0.0 0.1 0.0 0.0 0.1 16.4 0.1 0.8 0.0 63.0 119.9 0.0 0.0 0.0 0.0 0.0 0.0 22.1 4.0 103.9 0.0 1.3 20.9 2.8 0.2 3.5 0.5 1.4 0.3 66.6 0.0 0.2 0.0 0.1 0.0 2.2 0.6 0.1 6.9 12.7 0.1 0.0 0.1 0.1 0.0 49.3 2.0 4.6 0.1 51.9 0.1 2.6 2.0 6.6 13.4 3.4 9.7 5.5 10.8 13.3 2.3 4.8 9.4 8.6 3.3 7.5 7.9 2.1 6.5 5.5 3.6 4.4 3.7 5.1 3.6 4.8 5.8 4.7 5.6 5.0 7.8 7.2 3.6 3.2 10.2 1.0 44.9 5.4 10.4 4.9 4.6 0.2 1.2 1.5 1.9 1.5 6.5 0.0 0.0 0.4 52.3 3.7 0.0 1.0 0.7 1.0 0.6 3.2 1.2 17.1 0.4 1.3 1.4 2.3 2.0 1.8 41.2 0.1 5.7 0.5 30.5 0.0 0.4 1.4 14.2 28.2 44.6 0.5 0.0 22.0 7.2 24.4 30.2 0.2 85.5 1.0 2.7 0.6 3.6 0.4 20.2 2.9 0.9 0.4 2.1 0.2 0.0 0.3 2.0 0.4 0.6 8.4 4.5 0.5 68.6 2.7 7.0 10.7 TMCC3 KIAA1145 ENSG00000057704 "Transmembrane and coiled-coil domain family 3" Q9ULS5 12 94567122-94650557 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.3" "Cell type enhanced" "Detected in many" "Adipocytes: 81.2;Distal enterocytes: 98.3;Microglial cells: 70.3;Oligodendrocytes: 119.8;Paneth cells: 70.1;Urothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 46.9;neutrophil: 69.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 69.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 31.3;Karpas-707: 41.9;U-266/84: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014272 Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA014272: AB_1858059" "unprognostic (1.03e-1)" "unprognostic (2.54e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (5.87e-2)" "unprognostic (1.17e-2)" "unprognostic (9.12e-2)" "unprognostic (3.45e-3)" "unprognostic (1.24e-1)" "unprognostic (7.73e-2)" "unprognostic (1.80e-3)" "unprognostic (9.11e-2)" "unprognostic (2.32e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" 11.7 4.5 13.6 9.4 25.8 10.0 9.6 23.1 16.5 11.6 3.9 22.5 14.9 7.7 3.1 6.1 5.7 5.3 2.3 13.2 19.6 8.1 4.1 5.3 4.4 26.9 25.9 4.7 3.2 4.6 3.4 17.8 26.7 8.3 16.4 0.9 2.8 5.4 18.4 6.1 21.0 7.9 20.8 12.2 7.3 2.0 24.8 4.0 13.3 7.0 6.3 7.5 4.8 36.3 7.8 0.4 1.9 0.0 0.7 2.7 13.6 0.0 0.0 0.5 1.9 0.0 1.7 0.2 0.1 0.0 6.8 19.1 10.7 12.9 2.6 3.5 2.6 5.1 0.8 0.0 0.5 0.0 10.2 1.7 1.7 7.2 10.1 11.3 31.3 0.0 0.2 41.9 1.0 0.4 0.0 0.4 1.0 2.7 6.5 0.0 0.6 5.1 2.0 16.4 0.2 0.8 0.2 8.0 0.4 8.8 0.0 0.4 19.0 0.0 0.2 0.1 3.4 19.4 30.1 0.3 3.9 1.6 1.7 16.4 4.3 46.9 3.3 6.0 0.3 5.4 1.2 1.9 2.5 3.1 0.0 2.2 69.7 3.3 7.8 2.8 0.0 3.1 13.6 25.8 23.1 16.5 13.2 19.6 26.9 25.9 26.7 20.8 24.8 36.3 81.2 0.0 2.7 2.9 5.7 20.6 32.7 3.2 9.6 4.4 2.1 1.3 2.0 4.3 3.2 7.3 0.0 16.0 16.3 98.3 0.0 1.9 5.8 24.5 3.6 31.9 12.0 0.0 0.6 3.8 3.2 4.8 10.2 39.8 0.0 17.1 31.8 0.6 4.1 0.0 15.0 13.0 0.0 15.0 9.2 8.3 1.8 20.3 3.6 70.3 19.0 0.1 11.3 11.6 119.8 12.9 70.1 1.2 7.8 16.8 48.1 8.9 3.0 0.3 6.6 19.7 6.1 0.0 2.2 30.4 16.2 7.1 7.7 2.5 8.2 83.3 TMEM109 MGC5508 ENSG00000110108 "Transmembrane protein 109" Q9BVC6 11 60914158-60923443 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011785 Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear membrane, Cytosol" "HPA011785: AB_1858075" "unprognostic (5.23e-2)" "unprognostic (9.02e-2)" "unprognostic (2.46e-2)" "unprognostic (2.69e-2)" "unprognostic (1.23e-1)" "unprognostic (2.40e-2)" "unprognostic (5.29e-3)" "unprognostic (2.95e-1)" "unprognostic (2.70e-1)" "unprognostic (2.40e-2)" "unprognostic (2.52e-1)" "unprognostic (3.63e-2)" "unprognostic (1.83e-1)" "unprognostic (2.82e-1)" "unprognostic (1.51e-1)" "unprognostic (2.84e-2)" "prognostic unfavorable (2.68e-4)" 83.0 46.4 22.2 44.4 23.2 27.0 71.9 23.3 25.5 85.4 42.1 75.1 26.2 97.7 26.7 93.8 73.7 35.7 84.0 19.8 23.2 47.3 32.1 71.8 48.0 26.7 24.5 81.5 46.1 67.3 41.1 46.8 25.4 52.4 27.0 14.3 81.8 60.8 99.4 69.7 47.8 70.0 25.9 58.1 58.2 14.4 25.5 41.4 57.3 77.0 50.3 70.4 79.9 24.7 111.5 103.5 63.3 102.1 169.4 77.7 51.5 107.3 100.4 118.5 99.8 94.5 115.7 131.5 190.4 130.1 69.9 143.5 73.2 48.8 72.5 102.5 97.0 96.2 44.3 21.1 50.2 188.4 77.0 54.1 61.6 92.9 46.8 41.9 148.1 104.8 48.4 330.4 85.4 217.2 139.9 80.8 104.6 62.8 111.4 132.3 123.9 183.0 56.6 63.6 25.3 44.4 86.2 196.8 102.7 44.8 110.4 35.8 143.7 136.9 65.9 174.4 95.8 108.7 89.5 69.9 121.2 82.0 159.7 39.0 76.0 56.4 188.7 69.5 193.3 116.5 108.4 161.4 227.4 140.4 97.4 124.8 8.2 121.1 52.4 470.0 91.1 139.4 22.2 23.2 23.3 25.5 19.8 23.2 26.7 24.5 25.4 25.9 25.5 24.7 118.2 70.5 23.2 5.5 60.2 50.7 43.8 30.9 63.7 13.4 39.5 45.3 34.6 25.8 23.9 25.8 0.0 120.7 83.4 6.8 25.4 76.6 20.7 18.7 25.9 91.2 7.2 33.0 5.3 80.2 116.4 75.9 10.7 27.9 50.7 22.2 71.0 18.9 66.8 30.3 3.8 10.1 22.4 21.3 69.1 11.1 89.5 43.4 51.6 11.2 45.4 30.2 68.0 3.5 5.1 53.1 14.7 97.4 38.4 36.5 10.6 17.1 18.7 34.8 39.5 45.0 67.6 5.9 7.2 55.1 50.6 53.2 52.7 25.8 16.8 33.9 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM120A "NET29, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 289.1;Late spermatids: 1002.1;Proximal enterocytes: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.78e-2)" "unprognostic (3.35e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.26e-1)" "unprognostic (2.75e-3)" "unprognostic (6.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.15e-2)" 54.4 95.0 33.9 11.0 32.7 13.9 44.4 36.9 40.6 33.1 33.2 33.7 50.6 22.6 21.6 31.8 32.0 16.6 111.9 32.3 34.4 38.9 84.7 25.0 10.1 57.6 36.1 56.1 43.2 17.4 20.0 15.6 61.5 26.5 14.8 6.1 24.7 23.3 79.3 18.5 63.4 11.0 31.2 28.2 44.3 77.1 34.7 8.0 19.4 94.4 12.0 32.9 27.3 31.8 10.3 15.3 7.7 61.7 52.1 35.1 16.9 10.0 27.8 13.7 17.2 26.8 14.3 4.8 7.6 30.4 39.1 11.8 7.6 10.3 4.7 9.0 8.5 5.2 10.6 38.2 50.6 2.1 32.6 37.5 9.2 10.1 12.2 14.3 22.4 8.7 9.8 7.9 24.5 18.5 3.3 32.6 3.5 23.7 16.3 3.5 7.8 23.6 28.2 9.3 3.8 18.0 11.4 32.5 16.7 19.1 22.7 15.4 12.8 38.1 12.0 22.1 8.6 8.5 7.0 2.2 20.7 5.3 8.9 106.6 58.0 109.5 26.4 53.7 20.0 15.8 21.7 20.5 27.2 17.9 15.1 14.8 223.0 31.2 55.2 10.7 50.9 46.5 33.9 32.7 36.9 40.6 32.3 34.4 57.6 36.1 61.5 31.2 34.7 31.8 22.4 22.4 12.3 12.7 14.1 0.0 18.1 0.0 18.8 5.6 36.2 22.2 112.7 51.5 8.6 27.6 6.2 20.9 17.6 133.9 25.4 50.3 289.1 9.8 29.3 21.4 8.4 11.4 4.1 38.9 16.2 36.0 31.1 18.1 24.6 172.6 29.3 115.6 36.1 11.8 7.2 40.5 0.0 34.2 0.0 1002.1 40.4 36.0 0.0 3.7 23.7 12.8 18.6 4.0 7.3 40.0 108.9 30.9 24.6 17.4 414.8 118.0 4.4 7.0 39.5 46.0 31.2 113.4 15.4 33.1 0.0 10.9 20.0 31.0 43.6 28.1 TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 75.7;pancreas: 89.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 121.8;Alveolar cells type 2: 136.9;Distal enterocytes: 72.7;Proximal enterocytes: 164.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.8;BEWO: 21.8;CACO-2: 20.6;CAPAN-2: 48.3;OE19: 31.3;SK-BR-3: 41.2;T-47d: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" 0.3 0.7 17.4 3.2 32.2 0.2 11.5 27.6 29.9 16.4 12.8 21.2 35.4 1.6 18.3 10.9 15.5 11.3 0.9 17.0 20.7 16.4 1.1 75.7 0.3 31.5 28.5 1.4 89.6 22.2 31.0 4.4 29.0 22.0 21.0 0.1 31.8 7.1 0.0 12.9 27.5 0.8 22.6 0.3 27.4 1.5 26.8 0.4 44.9 0.0 2.5 2.9 3.4 42.8 26.8 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 20.6 48.3 0.1 1.2 0.0 0.0 11.7 0.0 7.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.1 0.1 0.1 1.1 31.3 0.0 0.0 0.0 0.7 0.4 8.5 12.4 0.1 0.0 41.2 0.0 3.6 33.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 17.4 32.2 27.6 29.9 17.0 20.7 31.5 28.5 29.0 22.6 26.8 42.8 0.2 121.8 136.9 0.0 0.9 0.0 2.3 18.0 0.6 0.0 30.4 15.2 0.5 42.9 56.0 16.5 0.0 33.5 0.1 72.7 17.6 39.1 3.7 20.1 1.4 0.6 21.7 0.0 0.2 38.5 2.2 0.6 45.3 13.1 1.3 4.9 0.0 0.0 2.4 0.0 0.2 63.0 34.6 0.0 0.2 7.9 0.3 0.6 0.0 0.0 0.6 1.7 1.0 0.0 55.3 22.7 40.1 1.2 0.6 12.2 164.2 33.9 43.8 0.0 0.0 0.0 2.3 1.4 0.3 2.1 0.4 7.3 1.0 0.1 38.6 9.1 TMEM132C "DKFZp761O2018, PPP1R152" ENSG00000181234 "Transmembrane protein 132C" Q8N3T6 12 128267403-128707915 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.6" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 217.3;Microglial cells: 160.2;Oligodendrocyte precursor cells: 580.6" "Group enriched" "Detected in some" 4 "glioma: 1.6;ovarian cancer: 4.6;testis cancer: 4.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "gdT-cell: 1.9" "Lineage enriched" "Detected in single" 19 "T-cells: 1.9" "Group enriched" "Detected in some" 7 "AF22: 3.7;ASC diff: 5.2;Daudi: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015633, HPA015984" Approved Centrosome,Cytosol NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Centrosome, Cytosol" "HPA015633: AB_1858089, HPA015984: AB_1858088" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (7.34e-2)" "unprognostic (8.60e-2)" "unprognostic (2.37e-1)" "unprognostic (1.99e-3)" "unprognostic (5.48e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.85e-2)" "unprognostic (6.29e-2)" "unprognostic (7.97e-3)" "unprognostic (2.54e-1)" "unprognostic (5.71e-2)" "unprognostic (6.33e-3)" 31.6 2.7 8.3 0.3 7.6 0.0 14.0 6.8 7.3 16.8 15.5 1.4 0.3 5.4 3.8 3.1 11.8 1.1 4.3 6.7 7.4 0.4 0.1 1.5 1.1 9.3 14.4 8.6 2.7 0.1 0.7 2.5 8.7 2.4 0.4 3.6 1.7 4.1 0.5 2.0 1.8 1.0 6.7 0.3 1.2 1.3 9.6 1.0 0.9 3.4 0.4 4.7 9.2 6.0 0.0 0.0 3.7 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.6 6.8 7.3 6.7 7.4 9.3 14.4 8.7 6.7 9.6 6.0 1.9 0.0 0.0 70.2 0.0 0.4 0.0 0.0 0.0 18.6 0.0 0.0 1.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 1.1 0.2 7.6 26.1 1.0 0.0 0.0 32.2 0.0 0.0 6.3 0.0 9.8 0.0 3.7 0.0 0.0 0.1 0.0 217.3 0.1 0.0 0.0 1.1 0.2 9.0 0.1 1.8 160.2 0.0 0.4 0.0 580.6 42.3 0.1 0.0 15.1 0.0 0.0 0.1 0.1 0.0 2.3 0.0 0.8 2.5 0.1 0.4 0.1 0.0 0.0 0.3 0.0 0.1 0.0 TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 18.1;Kupffer cells: 11.8;monocytes: 8.0;Proximal enterocytes: 68.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in some" "CACO-2: 8.3;HMC-1: 3.8;THP-1: 2.9;U-937: 18.1" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" 3.7 1.8 0.5 5.8 0.8 0.7 1.1 0.4 1.0 0.3 1.2 10.2 64.1 0.4 0.1 0.6 0.8 2.9 0.8 0.4 0.7 3.2 2.2 11.9 3.5 1.3 0.7 0.3 0.9 0.1 0.2 5.6 1.6 0.3 7.3 0.0 0.6 0.4 0.2 0.2 57.0 4.1 0.5 5.7 1.4 0.5 3.4 0.7 0.3 0.2 1.6 2.0 0.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.6 0.0 1.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.9 0.0 0.0 0.1 0.1 0.1 1.8 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 18.1 0.1 1.9 5.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.5 0.8 0.4 1.0 0.4 0.7 1.3 0.7 1.6 0.5 3.4 1.3 0.0 0.0 0.0 0.0 0.6 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.5 1.5 0.0 1.8 0.0 0.0 0.0 18.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.7 3.5 0.0 11.8 1.3 0.0 0.0 3.2 0.0 0.0 8.0 0.0 0.0 0.0 0.9 0.3 1.4 0.0 0.9 0.6 68.9 0.6 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 3.7 0.3 TMEM170B ENSG00000205269 "Transmembrane protein 170B" Q5T4T1 6 11537749-11583524 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.2" "Cell type enhanced" "Detected in many" "Astrocytes: 39.2;Excitatory neurons: 57.3;Inhibitory neurons: 52.3;Kupffer cells: 36.8;Macrophages: 31.5;monocytes: 45.8;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 22.1;U-937: 16.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055134 Uncertain Approved Centrosome NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Centrosome "HPA055134: AB_2682709" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.71e-4)" "unprognostic (6.67e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (4.62e-3)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (2.45e-5)" "unprognostic (3.49e-1)" "unprognostic (1.26e-1)" "unprognostic (4.27e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-4)" "unprognostic (3.97e-2)" 7.0 2.8 8.1 4.3 9.0 25.2 2.3 8.6 10.7 1.6 2.2 2.3 0.7 2.4 3.1 1.3 1.6 1.7 2.1 10.2 6.9 3.7 8.7 3.8 1.7 8.4 7.7 2.2 1.9 2.9 2.7 2.5 9.1 1.9 1.1 9.5 1.5 2.0 6.2 0.9 1.2 2.9 6.8 3.9 1.5 3.4 7.7 1.9 2.6 7.3 1.2 1.5 0.9 7.4 0.9 1.5 8.8 7.9 1.6 0.1 1.8 0.8 2.0 1.2 1.4 0.5 0.5 7.3 4.0 0.5 2.3 0.0 10.0 0.6 3.1 2.1 5.3 4.1 1.0 1.2 0.5 6.6 4.1 0.6 0.1 1.3 0.0 2.0 0.8 6.7 0.2 0.1 1.8 1.3 8.0 11.3 2.5 0.8 1.2 4.1 8.4 1.2 0.9 1.8 6.0 5.1 0.5 2.9 3.3 12.4 2.9 22.1 0.1 1.6 1.9 3.2 2.1 6.3 13.4 6.4 1.4 16.6 2.2 0.9 0.8 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.2 0.9 0.0 0.1 8.1 9.0 8.6 10.7 10.2 6.9 8.4 7.7 9.1 6.8 7.7 7.4 2.7 3.2 2.0 39.2 2.9 1.8 0.6 0.2 0.6 13.2 2.2 1.8 6.5 1.5 1.5 0.0 4.2 2.1 11.8 0.5 5.9 0.6 0.5 1.9 1.8 2.3 1.8 0.8 57.3 1.4 0.3 2.3 0.5 2.1 1.3 5.1 2.2 8.4 7.0 25.2 52.3 0.3 0.0 36.8 13.2 0.4 0.9 31.5 0.0 21.5 45.8 13.7 2.1 31.7 27.1 0.9 0.3 1.5 0.5 1.1 0.0 5.4 0.1 8.3 6.6 4.1 3.7 7.5 4.8 0.2 0.9 1.9 1.4 1.7 0.8 0.5 TMEM210 ENSG00000185863 "Transmembrane protein 210" A6NLX4 9 137170858-137172056 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 14.8" "Group enriched" "Detected in some" 68 "Early spermatids: 900.5;Late spermatids: 1815.1" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "plasmacytoid DC: 3.2" "Lineage enriched" "Detected in single" 33 "dendritic cells: 3.2" "Cell line enriched" "Detected in some" 8 "RPMI-8226: 13.5" "Not detected" "Not detected" HPA066907 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA066907: AB_2685747" "unprognostic (5.17e-2)" "unprognostic (5.04e-2)" "unprognostic (2.87e-5)" "unprognostic (4.18e-2)" "unprognostic (3.63e-2)" "unprognostic (3.14e-2)" "unprognostic (8.00e-2)" 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 900.5 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.7 1815.1 12.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 1.1 0.0 0.0 0.0 0.0 19.7 0.0 0.1 9.1 4.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 TMEM213 ENSG00000214128 "Transmembrane protein 213" A2RRL7 7 138797952-138838101 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 76.0;salivary gland: 52.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 53.3;Distal tubular cells: 144.8;Melanocytes: 26.6" "Cancer enriched" "Detected in some" 22 "renal cancer: 21.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 2.1;neutrophil: 1.1;NK-cell: 2.0" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.0" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054059 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA054059: AB_2682361" "unprognostic (2.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (6.84e-2)" "unprognostic (1.17e-2)" "unprognostic (2.10e-1)" "unprognostic (6.14e-2)" "unprognostic (6.08e-2)" "unprognostic (1.91e-2)" "prognostic favorable (5.54e-7)" "unprognostic (4.33e-1)" "unprognostic (9.99e-2)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" 0.1 0.1 0.5 0.2 0.5 1.1 4.7 0.6 0.7 2.8 0.4 0.1 1.3 0.2 0.6 0.3 0.1 0.2 0.0 0.6 0.1 76.0 0.1 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.1 0.3 52.3 1.2 0.1 5.3 0.3 0.1 0.0 0.2 0.4 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 2.1 0.2 0.2 0.3 0.2 0.4 0.2 0.1 0.2 0.1 0.3 0.2 0.1 1.1 2.0 0.2 0.2 0.1 0.1 0.5 0.5 0.6 0.7 0.6 0.1 0.2 0.1 0.4 0.0 0.5 1.0 0.1 3.2 9.9 0.0 0.1 0.0 0.9 3.0 0.0 0.4 14.1 7.9 0.4 0.0 4.4 53.3 0.0 0.0 0.2 0.0 144.8 0.0 0.0 0.9 0.4 0.5 0.0 0.0 0.6 0.2 0.1 0.2 0.0 1.3 1.3 0.1 0.0 0.0 0.1 1.7 0.4 0.0 2.0 0.0 0.8 0.0 0.0 0.1 26.6 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 3.5 1.3 0.0 0.5 0.2 0.0 0.2 0.0 0.4 0.0 0.6 0.0 0.2 0.6 TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 502.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA009078: AB_1078345, HPA061421: AB_2684513" "unprognostic (1.39e-1)" "unprognostic (3.61e-1)" "unprognostic (3.73e-1)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (9.67e-3)" "unprognostic (5.85e-3)" "unprognostic (4.34e-3)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-2)" "unprognostic (9.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.55e-2)" 140.5 120.1 89.7 60.4 98.6 60.4 88.4 101.9 110.7 108.3 113.6 83.9 62.3 88.9 120.4 57.3 87.1 97.7 101.4 88.2 100.2 145.7 197.8 75.8 81.0 98.9 95.1 97.4 95.1 99.3 89.5 72.5 99.1 105.5 88.7 107.4 78.9 83.1 107.1 34.4 70.2 88.9 95.3 71.8 87.6 49.7 96.0 85.6 135.5 148.3 76.6 93.3 56.6 111.8 157.2 108.1 139.1 105.2 307.1 271.6 105.6 124.0 185.4 119.9 131.4 86.0 152.4 74.8 99.5 180.7 136.6 127.1 104.5 185.2 172.3 83.6 119.6 132.6 31.5 266.3 196.3 154.9 52.8 189.3 202.4 92.2 183.3 167.0 160.1 163.6 126.1 200.3 199.2 44.7 156.9 143.8 106.3 298.8 152.4 100.4 93.2 161.5 182.5 79.4 116.8 141.7 74.6 154.8 270.0 149.0 123.9 145.6 135.7 154.7 90.5 150.1 135.2 133.2 284.3 147.5 62.5 132.2 166.3 128.9 175.4 116.7 136.5 187.1 166.3 170.7 145.8 145.3 163.8 153.1 150.8 148.6 55.7 153.9 180.6 161.2 147.6 349.2 89.7 98.6 101.9 110.7 88.2 100.2 98.9 95.1 99.1 95.3 96.0 111.8 126.6 57.7 64.6 15.3 123.4 70.4 126.7 148.7 65.4 89.6 151.7 133.7 51.3 111.5 95.1 154.5 64.6 173.4 127.8 55.0 502.9 146.6 200.3 77.1 103.2 109.5 95.8 103.7 20.2 111.2 208.8 141.6 59.1 64.1 114.1 82.8 126.7 147.5 212.8 62.2 27.7 123.1 126.1 162.9 172.9 89.5 212.2 121.9 199.3 14.0 215.6 113.9 151.4 13.0 49.6 100.2 130.0 220.4 161.7 129.6 102.0 363.2 81.9 113.3 85.5 100.4 128.0 99.4 97.5 68.1 60.5 148.0 118.2 184.2 125.6 152.1 TMEM233 "DSPB2, IFITMD2" ENSG00000224982 "Transmembrane protein 233" B4DJY2 12 119593774-119643075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 66.6;tongue: 21.2" "Group enriched" "Detected in some" 5 "granulocytes: 79.1;Skeletal myocytes: 77.8" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 22.2;hTERT-RPE1: 9.0;RH-30: 11.8;U-2197: 17.9;U-87 MG: 70.3" "Not detected" "Not detected" "HPA047506, HPA075435" Uncertain Approved Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "HPA047506: AB_10963068, HPA075435: " "unprognostic (1.46e-2)" "unprognostic (1.16e-2)" "unprognostic (1.39e-3)" "unprognostic (1.03e-2)" "unprognostic (1.99e-3)" "unprognostic (1.71e-2)" "unprognostic (5.86e-2)" "unprognostic (1.55e-2)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-2)" "unprognostic (4.41e-2)" "unprognostic (6.06e-2)" "unprognostic (3.10e-3)" "unprognostic (2.94e-1)" "unprognostic (4.38e-2)" "unprognostic (3.66e-1)" 0.7 0.6 4.6 0.1 6.6 0.0 0.4 1.1 9.0 0.4 1.3 0.2 0.2 0.3 0.2 0.3 0.2 0.5 1.2 4.4 2.5 1.3 0.6 0.9 0.2 1.8 1.4 0.9 0.2 1.3 0.8 0.1 1.8 0.6 0.2 0.2 0.5 0.3 66.6 0.1 0.3 0.4 1.4 0.2 0.3 0.2 3.4 0.9 14.3 21.2 0.2 1.0 0.3 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 1.7 0.0 22.2 0.0 9.0 0.1 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 70.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 6.6 1.1 9.0 4.4 2.5 1.8 1.4 1.8 1.4 3.4 4.4 12.0 3.2 1.1 0.7 0.0 0.0 0.4 0.0 0.0 2.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.9 9.5 0.3 0.1 13.3 0.0 0.0 5.4 8.5 0.0 3.6 0.0 0.4 79.1 5.5 15.4 0.1 0.1 8.4 3.7 0.0 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.5 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.4 0.0 77.8 2.2 3.1 1.0 0.2 0.1 0.1 0.9 9.2 0.0 0.2 TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Endothelial cells: 81.5;granulocytes: 39.3;Hepatic stellate cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Cell line enhanced" "Detected in many" "HMC-1: 28.6;HUVEC TERT2: 38.8;PC-3: 39.3;RPMI-8226: 25.1;TIME: 35.9;U-87 MG: 40.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" 14.2 6.1 1.3 3.7 1.3 0.7 10.6 1.1 2.2 10.1 2.1 4.0 1.6 8.4 0.3 3.9 8.1 3.6 6.6 1.6 3.7 10.1 3.4 13.2 2.4 2.1 1.3 4.3 3.1 1.6 3.5 1.0 1.7 7.0 1.4 0.4 4.2 2.2 2.9 4.2 4.8 5.0 1.4 8.2 4.3 3.3 1.9 0.8 11.2 3.9 1.8 7.5 7.1 1.5 10.3 0.0 0.6 0.0 2.8 0.0 0.1 4.8 10.7 5.5 3.5 0.4 0.2 0.2 0.1 7.7 12.5 1.5 1.1 0.7 2.3 0.1 0.9 0.3 0.4 0.0 1.4 2.9 28.6 1.8 2.3 11.7 4.6 15.7 38.8 0.6 0.1 0.2 12.0 0.2 1.5 0.9 1.0 1.6 39.3 1.8 0.8 25.1 5.4 0.5 2.2 5.1 0.2 1.5 0.1 1.0 0.6 8.2 35.9 1.6 10.3 0.6 1.7 0.0 0.0 1.9 40.6 2.7 0.3 31.2 5.4 0.7 0.0 5.5 0.0 0.9 0.0 0.0 1.5 2.8 0.0 0.0 2.7 0.0 4.0 0.0 0.0 1.4 1.3 1.3 1.1 2.2 1.6 3.7 2.1 1.3 1.7 1.4 1.9 1.5 65.0 6.4 4.8 2.3 1.9 5.9 1.2 0.9 1.2 0.9 1.1 1.7 9.1 0.0 0.2 1.8 0.0 0.1 0.3 0.0 1.9 8.2 0.8 0.3 0.8 81.5 1.2 3.2 2.7 1.7 0.1 4.7 0.0 0.2 39.3 2.3 105.0 0.7 12.9 0.0 0.1 0.2 0.0 17.4 14.6 1.1 7.8 16.3 8.8 7.5 3.4 0.5 0.0 0.0 0.6 1.3 0.1 3.0 1.4 1.7 0.0 0.1 0.5 0.8 6.6 0.9 3.6 5.1 19.1 0.2 4.7 0.0 1.8 2.1 0.3 1.0 TMEM26 "Em:AC068892.1, MGC35010" ENSG00000196932 "Transmembrane protein 26" Q6ZUK4 10 61406642-61453381 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.2;Endometrial stromal cells: 5.4;Excitatory neurons: 5.3;Hepatic stellate cells: 4.6;Inhibitory neurons: 4.8;Kupffer cells: 12.2;Late spermatids: 5.6;Theca cells: 15.0" "Group enriched" "Detected in some" 4 "breast cancer: 2.5;endometrial cancer: 1.0;prostate cancer: 1.8;renal cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.7;fHDF/TERT166: 1.1;HSkMC: 2.0;HUVEC TERT2: 1.5;MOLT-4: 2.3" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.21e-3)" "unprognostic (2.84e-1)" "unprognostic (7.34e-2)" "unprognostic (7.83e-2)" "unprognostic (1.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.56e-2)" "unprognostic (3.69e-2)" "unprognostic (3.13e-1)" "unprognostic (9.41e-2)" "unprognostic (5.38e-2)" "unprognostic (5.24e-2)" "unprognostic (2.29e-5)" "unprognostic (2.55e-2)" "unprognostic (1.51e-2)" "unprognostic (8.53e-2)" "unprognostic (1.95e-1)" 0.5 0.5 1.3 0.9 1.4 0.1 5.2 0.3 1.1 2.3 0.2 0.7 1.4 4.0 0.1 0.5 0.4 1.0 0.2 1.1 0.8 2.2 2.5 1.4 0.7 0.8 1.0 0.5 0.0 1.4 0.2 1.5 0.4 2.6 0.9 0.0 0.0 2.4 0.8 0.0 0.8 2.0 0.5 8.8 0.2 3.6 1.5 2.1 0.4 0.2 0.2 0.7 0.5 0.7 0.0 0.0 0.1 0.0 0.1 0.8 0.1 0.0 4.7 0.4 0.6 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.5 0.0 0.5 1.5 0.5 0.0 0.0 0.1 0.0 2.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.4 0.3 1.1 1.1 0.8 0.8 1.0 0.4 0.5 1.5 0.7 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 2.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.7 5.4 1.7 0.0 0.0 5.3 0.0 0.0 1.4 0.0 1.6 0.0 0.1 4.6 0.2 0.3 0.0 4.8 0.0 0.0 12.2 0.0 5.6 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.1 1.2 0.5 0.2 0.0 0.1 0.0 0.1 15.0 0.0 0.0 TMEM273 "C10orf128, Em:AC084727.5" ENSG00000204161 "Transmembrane protein 273" Q5T292 10 49154725-49188585 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 37.8;dendritic cells: 10.1;Hofbauer cells: 82.9;Macrophages: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 269.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 269.0" "Cell line enhanced" "Detected in some" "HDLM-2: 214.8;HEL: 51.7;K-562: 101.4;U-266/84: 38.3;U-87 MG: 102.2;U-937: 91.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058166 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA058166: AB_2683627" "unprognostic (1.33e-1)" "unprognostic (5.67e-4)" "unprognostic (1.34e-2)" "unprognostic (1.21e-1)" "unprognostic (4.50e-2)" "unprognostic (4.13e-2)" "unprognostic (5.86e-3)" "unprognostic (9.13e-3)" "unprognostic (2.61e-1)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (2.86e-5)" "unprognostic (2.45e-2)" "unprognostic (2.22e-2)" "unprognostic (8.69e-3)" "unprognostic (1.24e-1)" 31.5 3.0 15.1 17.2 22.1 4.0 27.5 23.0 27.1 15.1 13.4 12.8 8.8 13.7 6.1 8.4 12.8 18.3 28.0 15.2 18.2 6.0 9.5 27.1 22.2 25.0 22.8 3.9 4.0 14.4 3.3 10.9 25.0 8.2 14.2 1.1 9.8 7.8 8.5 7.3 24.3 20.9 18.9 29.8 8.9 1.9 20.5 7.8 10.2 16.5 23.4 14.4 12.7 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 214.8 0.0 51.7 0.0 0.0 0.0 0.5 21.9 0.0 0.0 0.0 0.0 0.0 1.4 0.2 101.4 6.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.3 0.0 0.0 0.0 0.1 0.0 38.3 0.1 102.2 91.6 0.0 24.9 4.2 269.0 22.9 1.4 36.5 35.9 13.8 22.0 19.8 18.5 0.7 6.1 19.4 0.2 0.7 0.6 11.2 11.5 15.1 22.1 23.0 27.1 15.2 18.2 25.0 22.8 25.0 18.9 20.5 30.7 37.8 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 1.8 0.0 0.8 10.1 0.0 0.0 0.1 0.0 1.1 0.2 9.4 0.0 0.0 0.0 0.0 0.7 0.5 0.0 2.0 0.0 0.0 0.0 0.0 82.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.1 5.6 0.0 0.0 0.0 TMEM35B ZMYM6NB ENSG00000243749 "Transmembrane protein 35B" Q8NCS4 1 34981535-34985353 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 13.4;Club cells: 6.2;granulocytes: 8.8;Respiratory ciliated cells: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 115.3;CAPAN-2: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051024 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 44: Non-specific - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" "HPA051024: AB_2681316" "unprognostic (3.34e-3)" "unprognostic (2.77e-3)" "unprognostic (4.25e-1)" "unprognostic (2.12e-2)" "unprognostic (5.52e-2)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "unprognostic (7.51e-3)" "unprognostic (2.32e-1)" "unprognostic (9.41e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (5.49e-2)" "unprognostic (4.53e-3)" "unprognostic (1.07e-1)" 48.9 36.0 12.6 25.1 12.5 13.6 40.1 12.4 18.5 41.6 16.9 27.4 16.6 36.2 39.0 15.4 41.3 41.0 32.3 12.4 13.1 36.8 40.1 44.2 40.0 13.8 12.8 32.5 29.6 29.8 21.8 63.4 13.7 30.4 26.6 2.2 25.8 34.8 8.6 13.3 27.6 30.1 13.7 32.5 24.4 22.6 13.4 29.7 44.7 20.4 30.9 36.2 33.3 14.4 25.8 19.5 4.2 7.3 115.3 67.1 9.3 27.7 46.2 19.1 25.8 19.4 113.1 12.6 42.1 28.4 30.3 27.2 8.1 23.4 15.0 49.2 12.9 27.2 9.0 23.1 63.2 18.0 27.5 67.7 21.3 17.4 36.6 39.1 38.3 26.8 17.5 36.2 34.2 16.2 13.3 18.6 20.2 0.0 13.6 17.7 37.3 4.0 53.6 24.9 11.1 3.5 42.4 0.6 39.5 21.3 10.3 27.9 39.4 25.6 24.0 22.7 15.8 20.9 12.7 8.9 25.7 29.4 22.2 161.3 101.2 112.4 188.7 118.6 202.9 108.9 205.0 208.3 71.3 89.9 177.7 179.9 31.4 165.4 100.4 159.5 232.4 182.9 12.6 12.5 12.4 18.5 12.4 13.1 13.8 12.8 13.7 13.7 13.4 14.4 0.6 22.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 6.2 0.0 0.0 0.1 0.2 0.0 0.0 1.0 0.0 0.3 0.7 2.1 0.0 0.0 0.0 0.2 0.2 2.0 0.0 0.3 8.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 15.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 101.1;liver: 100.0;parathyroid gland: 124.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.9;Hepatocytes: 184.5;Muller glia cells: 146.8;Proximal enterocytes: 575.7;Proximal tubular cells: 188.1" "Cancer enhanced" "Detected in all" "renal cancer: 57.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "EFO-21: 26.9;Hep G2: 74.7;RPTEC TERT1: 60.0" "Low region specificity" "Detected in all" HPA053794 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA053794: AB_2682265" "unprognostic (2.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.01e-1)" "unprognostic (4.59e-3)" "unprognostic (2.56e-1)" "unprognostic (9.60e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-1)" "unprognostic (2.83e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-2)" "unprognostic (2.99e-1)" "unprognostic (2.61e-2)" 53.1 11.1 2.1 6.6 2.0 0.7 25.6 1.8 3.6 21.9 2.5 37.3 53.5 6.4 4.8 6.8 3.4 23.2 4.8 1.5 1.8 101.1 100.0 15.4 10.2 2.5 2.1 12.7 13.3 124.7 1.0 14.9 2.3 3.9 19.0 23.6 7.0 7.6 2.4 10.5 76.1 4.8 2.5 25.7 18.1 5.1 3.7 3.0 31.1 4.2 4.9 7.0 5.6 3.2 0.0 7.3 0.7 0.3 4.3 0.4 1.0 0.2 0.1 0.0 0.1 11.4 6.4 0.0 26.9 3.4 0.6 1.7 3.0 0.0 0.0 0.0 2.9 1.0 4.0 74.7 5.9 0.0 0.1 9.7 0.0 0.0 0.0 0.2 5.9 0.0 0.2 10.9 0.0 0.7 0.0 0.8 5.4 0.1 0.2 0.0 0.1 9.9 60.0 4.9 0.9 0.4 0.3 2.9 0.0 5.0 1.2 1.7 3.8 0.0 10.4 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.1 2.0 1.8 3.6 1.5 1.8 2.5 2.1 2.3 2.5 3.7 3.2 12.2 25.6 9.6 0.0 3.2 2.0 0.3 11.1 0.0 2.4 1.8 1.5 2.1 82.9 13.6 18.4 0.0 64.9 0.1 179.9 50.9 36.1 0.3 7.7 98.8 15.1 9.1 5.3 0.0 52.3 3.8 17.9 11.7 10.3 1.3 16.4 61.8 184.5 64.6 6.7 0.0 22.0 14.2 65.5 5.0 1.9 49.7 19.5 1.8 0.0 0.6 146.8 0.0 0.0 0.6 15.3 68.1 3.8 0.0 0.1 575.7 188.1 7.6 17.4 0.0 0.9 14.8 0.0 0.8 1.0 2.8 104.1 2.4 45.3 23.3 2.3 TMEM43 "ARVD5, DKFZp586G1919, LUMA, MGC3222" ENSG00000170876 "Transmembrane protein 43" Q9BTV4 3 14125015-14143680 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019198 Approved NA NA 34000 "Cluster 5: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA019198: AB_1858118" "unprognostic (3.65e-3)" "unprognostic (2.52e-1)" "unprognostic (4.03e-2)" "unprognostic (4.66e-1)" "unprognostic (5.45e-3)" "unprognostic (1.72e-1)" "unprognostic (1.28e-3)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.77e-2)" "unprognostic (5.45e-2)" "unprognostic (1.35e-3)" "unprognostic (2.19e-1)" "unprognostic (9.78e-2)" "unprognostic (1.18e-1)" 75.4 34.3 23.1 36.8 23.8 21.0 61.3 23.0 25.3 66.8 23.5 56.7 23.5 89.1 31.0 69.5 63.9 47.1 64.7 23.2 25.0 27.7 19.6 58.1 30.2 27.5 25.1 82.6 27.3 25.6 30.6 57.6 25.9 43.3 29.4 15.9 37.9 65.2 60.8 108.7 40.0 82.5 23.6 31.2 34.8 15.2 25.5 26.0 47.0 45.8 33.7 56.1 66.4 25.2 41.5 45.7 44.1 58.3 173.4 180.6 104.6 80.1 164.8 129.9 93.0 37.5 54.1 19.5 55.7 201.3 64.3 88.3 47.1 70.9 92.9 48.7 38.0 35.3 45.6 53.8 109.3 51.4 40.4 136.0 173.6 107.9 133.0 103.6 94.8 36.2 56.1 47.8 76.6 54.3 23.4 43.2 48.4 62.8 75.3 32.2 46.8 78.2 59.4 70.4 12.9 35.5 101.0 59.3 66.5 37.3 37.5 74.3 86.4 118.7 63.7 120.6 76.0 32.1 54.3 25.1 89.3 68.4 108.7 81.3 51.5 100.3 68.7 45.5 64.0 36.8 66.8 62.7 67.4 31.6 44.5 49.0 157.2 79.9 49.2 42.6 65.7 69.7 23.1 23.8 23.0 25.3 23.2 25.0 27.5 25.1 25.9 23.6 25.5 25.2 44.2 137.8 46.8 17.9 16.8 43.7 32.2 31.0 39.9 6.2 19.9 29.7 13.4 15.7 52.9 18.4 14.6 31.2 43.2 9.3 0.0 34.9 0.6 17.3 58.1 37.4 4.9 22.5 24.1 10.0 65.6 68.0 20.9 34.4 28.4 16.1 23.6 8.9 17.8 6.7 20.6 8.3 8.2 16.1 33.5 3.9 43.2 19.8 30.2 15.9 26.8 8.4 16.5 30.2 23.9 22.4 9.7 70.7 15.6 35.8 8.8 9.0 16.2 8.6 32.9 43.6 39.3 5.6 12.0 44.1 45.5 37.5 32.1 17.6 11.5 30.2 TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.5;intestine: 136.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 325.6;Paneth cells: 221.6;Proximal enterocytes: 288.7;Respiratory ciliated cells: 133.9;Undifferentiated cells: 122.2;Urothelial cells: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.0;naive CD4 T-cell: 3.6;neutrophil: 11.7" "Group enriched" "Detected in many" 14 "granulocytes: 11.7;T-cells: 3.6" "Group enriched" "Detected in some" 5 "OE19: 333.1;RT4: 133.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA015474: , HPA015878: AB_2205046" "unprognostic (4.92e-3)" "unprognostic (7.94e-2)" "unprognostic (5.98e-2)" "unprognostic (1.81e-1)" "unprognostic (5.44e-3)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (6.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-3)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-2)" "unprognostic (2.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" 0.7 0.6 1.5 8.3 1.6 1.1 13.2 1.9 1.8 14.9 7.6 95.1 136.4 1.1 13.6 66.5 21.7 24.1 0.1 2.1 2.0 20.6 24.7 6.0 0.9 1.5 2.8 0.2 1.2 12.4 4.2 1.4 1.5 3.6 94.6 0.4 15.4 8.2 0.3 25.4 127.4 2.8 0.9 0.8 24.3 0.3 2.0 0.4 6.5 0.0 15.0 30.8 27.3 1.4 0.1 0.1 0.1 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 39.1 16.8 0.2 7.0 0.0 0.2 22.3 0.0 0.0 0.0 0.1 0.5 0.3 2.1 40.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.4 0.2 0.2 0.1 0.0 13.3 0.2 1.5 0.2 333.1 49.2 0.3 0.1 2.6 21.0 133.1 4.1 0.6 0.2 10.8 0.1 0.1 37.1 0.2 0.3 0.2 0.3 0.4 0.1 0.2 0.1 0.4 0.1 0.3 0.1 1.2 0.5 0.1 0.2 0.1 0.2 0.2 3.0 0.8 0.0 0.4 3.6 0.6 11.7 0.5 0.1 0.3 0.5 0.9 1.5 1.6 1.9 1.8 2.1 2.0 1.5 2.8 1.5 0.9 2.0 1.4 0.1 19.2 12.5 0.3 1.1 3.3 16.4 29.1 0.0 0.1 6.7 2.5 0.8 18.6 68.8 46.0 0.0 3.8 0.0 325.6 13.7 26.9 0.4 27.7 2.9 1.0 55.4 0.0 0.8 8.6 0.8 0.8 17.9 29.5 2.5 0.3 0.4 8.4 0.5 0.0 0.4 49.3 20.3 0.6 0.4 0.3 0.3 2.9 3.6 2.8 0.1 0.1 0.0 0.0 0.3 50.2 221.6 0.0 0.0 23.8 288.7 1.4 133.9 0.2 0.0 0.7 3.6 0.1 0.2 4.4 20.9 0.4 1.8 0.1 122.2 162.0 TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 59.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 999.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.4" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "Focal adhesion sites" "HPA021134: AB_2205162" "unprognostic (5.28e-2)" "unprognostic (2.60e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-2)" "unprognostic (3.93e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (2.88e-2)" "unprognostic (2.19e-2)" "prognostic favorable (6.96e-4)" "unprognostic (3.00e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.02e-5)" "unprognostic (1.15e-3)" "unprognostic (1.84e-2)" "unprognostic (4.07e-2)" "unprognostic (2.29e-2)" 12.8 12.0 5.7 4.4 9.2 6.7 12.1 6.8 8.3 6.8 6.3 14.2 16.4 8.9 6.8 6.0 7.0 6.2 13.9 5.7 7.2 18.3 59.5 10.5 4.0 8.5 8.5 10.6 8.3 6.3 10.1 3.9 8.5 7.2 6.9 7.1 7.2 3.3 7.6 6.6 14.6 4.2 5.8 6.3 10.1 34.9 8.8 3.3 7.9 3.7 2.1 7.5 6.1 15.4 12.9 14.7 13.0 9.6 16.6 12.5 15.6 3.8 11.1 7.2 10.5 4.7 39.9 4.1 11.8 3.6 27.4 11.5 3.6 7.8 3.8 6.5 9.2 4.7 6.0 22.7 16.5 3.7 16.6 14.8 11.9 14.4 3.1 7.9 4.0 9.1 2.0 5.1 4.3 7.7 4.5 11.2 7.6 9.9 8.5 6.8 1.8 40.0 21.6 13.4 9.0 8.7 4.1 15.7 21.3 9.3 4.8 9.9 1.7 5.3 8.8 7.5 4.7 3.7 4.7 2.3 13.6 9.6 6.3 14.1 12.9 6.3 7.3 23.1 6.3 13.9 7.4 6.3 6.6 14.8 3.5 4.5 1.4 7.8 16.2 99.4 8.1 7.6 5.7 9.2 6.8 8.3 5.7 7.2 8.5 8.5 8.5 5.8 8.8 15.4 10.9 6.4 12.0 8.1 3.5 1.7 9.5 24.2 1.8 6.9 9.0 7.6 35.5 10.0 20.4 20.2 4.2 14.5 9.5 53.1 45.0 18.6 188.3 14.0 4.6 8.5 14.4 10.1 2.9 25.7 15.5 6.9 8.2 5.7 6.3 8.6 10.0 93.0 34.3 18.5 3.6 22.6 44.7 12.6 0.7 999.9 9.0 14.0 8.8 1.9 3.8 17.1 5.2 3.0 4.8 17.5 51.3 12.4 2.6 8.9 74.3 45.9 32.8 13.8 26.3 3.7 10.6 15.6 13.2 3.9 2.3 9.3 3.7 8.3 18.0 12.7 TMEM63C "C14orf171, CSC1, DKFZp434P0111, hsCSC1" ENSG00000165548 "Transmembrane protein 63C" Q9P1W3 14 77116568-77259495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7;pituitary gland: 41.9" "Cell type enhanced" "Detected in some" "Early spermatids: 9.5;Enteroendocrine cells: 19.2;Excitatory neurons: 25.8;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 16.1" "Cancer enhanced" "Detected in many" "breast cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.5;Karpas-707: 24.1;RPMI-8226: 12.7;SCLC-21H: 32.5;SK-BR-3: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030657 Uncertain Approved Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "HPA030657: AB_10601699" "unprognostic (2.74e-1)" "unprognostic (1.79e-2)" "unprognostic (2.30e-1)" "unprognostic (4.30e-8)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (2.68e-3)" "unprognostic (1.61e-3)" "unprognostic (2.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.90e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.34e-7)" "unprognostic (5.90e-3)" 0.2 9.6 9.2 0.6 5.9 0.8 3.3 28.7 10.5 2.6 0.0 4.5 1.2 0.1 4.5 6.4 0.2 0.2 0.9 5.6 24.6 0.5 0.1 0.5 0.3 4.5 8.3 0.1 4.8 1.5 41.9 0.7 16.9 0.2 3.0 2.4 2.7 0.0 0.5 9.7 2.7 0.6 4.2 3.3 1.9 11.3 18.2 0.1 2.2 0.4 0.3 0.0 7.1 4.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 18.5 3.4 0.0 3.0 2.5 3.8 1.5 0.0 1.2 1.4 0.3 1.8 0.0 0.0 3.2 0.1 0.0 7.5 0.0 0.2 0.0 0.0 8.7 0.0 24.1 0.0 9.3 2.6 0.1 0.8 0.0 0.0 0.0 1.2 12.7 0.3 0.0 32.5 4.9 0.4 29.1 0.0 0.6 2.8 1.6 0.0 0.0 5.9 0.0 0.0 1.9 0.1 0.7 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 0.1 9.2 5.9 28.7 10.5 5.6 24.6 4.5 8.3 16.9 4.2 18.2 4.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 3.3 2.2 0.8 0.7 0.0 1.7 0.0 2.1 0.0 1.5 3.8 1.9 0.0 9.5 0.3 0.4 0.1 19.2 0.0 25.8 0.2 0.1 0.3 0.0 2.4 0.0 0.2 0.0 0.0 2.7 3.3 22.2 3.0 4.1 0.0 0.0 6.2 0.0 0.2 0.0 3.7 0.6 0.3 0.0 16.1 1.1 0.2 7.0 0.4 0.1 0.0 0.5 0.2 0.1 0.6 0.0 0.0 0.3 0.6 0.1 2.4 0.0 0.0 0.2 0.7 0.7 0.1 TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.6;Theca cells: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" 2.8 2.7 2.6 2.2 2.2 0.3 3.2 2.1 2.8 2.3 3.8 1.5 1.4 2.2 1.0 2.3 2.6 4.0 2.9 2.1 2.6 9.5 2.6 3.5 4.7 3.1 2.7 7.1 3.4 5.4 2.2 4.3 2.5 1.6 1.8 5.7 2.7 1.4 2.9 17.6 2.0 1.9 2.7 4.9 2.1 2.3 4.0 1.6 2.1 2.5 2.5 2.3 3.6 4.5 0.0 0.2 0.6 3.1 2.7 0.0 0.1 0.6 0.5 0.5 0.5 0.0 0.4 0.0 1.2 0.6 3.0 0.3 0.2 0.1 0.3 0.2 1.9 0.2 0.1 0.0 2.1 0.0 2.8 3.8 1.2 0.1 0.2 0.7 1.7 1.8 0.6 0.0 1.3 1.7 0.0 0.0 0.2 0.5 1.6 0.0 5.1 0.0 17.5 3.8 1.0 1.3 1.0 3.2 1.4 1.1 3.9 0.4 1.9 0.5 0.2 0.1 0.1 3.2 2.7 0.0 1.1 0.0 1.1 0.0 1.9 0.1 0.2 1.4 0.5 0.0 0.2 0.4 3.4 0.1 0.4 0.8 0.0 0.1 0.5 2.0 0.5 0.8 2.6 2.2 2.1 2.8 2.1 2.6 3.1 2.7 2.5 2.7 4.0 4.5 1.9 0.0 0.0 0.3 0.0 0.1 0.8 0.4 0.0 5.2 3.5 1.8 2.2 0.0 0.7 11.0 8.4 0.5 1.4 0.6 7.9 7.8 12.2 1.1 1.9 2.1 3.5 0.0 0.5 8.0 0.3 1.7 1.1 1.0 0.0 3.0 3.9 1.6 40.6 0.0 0.8 0.8 0.0 12.7 0.8 12.1 2.1 8.3 0.0 3.7 2.3 2.6 0.0 2.0 0.1 7.4 0.1 1.9 0.4 0.6 0.0 8.3 0.4 4.8 6.6 0.4 1.2 7.8 2.6 0.2 0.3 2.3 0.7 17.4 0.2 0.4 TMIE DFNB6 ENSG00000181585 "Transmembrane inner ear" Q8NEW7 3 46694528-46710886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.6;choroid plexus: 10.5;pituitary gland: 9.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.8;Spermatocytes: 2.6;Spermatogonia: 3.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.4" "Lineage enriched" "Detected in single" 15 "T-cells: 2.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.1;EFO-21: 2.7;JURKAT: 10.7;SH-SY5Y: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038298 Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cytosol" "HPA038298: AB_10675792" "unprognostic (6.59e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-3)" "unprognostic (2.48e-3)" "unprognostic (1.88e-2)" "unprognostic (5.40e-3)" "unprognostic (3.94e-2)" "unprognostic (8.80e-2)" "unprognostic (3.37e-2)" "unprognostic (6.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.35e-2)" "unprognostic (4.58e-2)" "unprognostic (1.23e-1)" "unprognostic (4.41e-2)" "unprognostic (5.29e-2)" "unprognostic (6.78e-2)" 0.7 6.2 14.2 0.5 14.1 0.0 0.4 14.0 18.0 0.7 10.5 1.0 0.4 0.5 0.7 1.5 0.6 0.2 0.7 14.1 19.3 2.3 0.8 1.0 0.8 19.6 15.7 1.5 0.2 0.1 9.9 0.4 19.2 0.5 0.3 0.7 0.5 1.0 3.6 0.7 0.5 0.4 16.0 0.7 0.3 1.5 18.7 0.5 0.9 1.2 0.8 0.6 0.9 14.9 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 2.7 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 0.0 1.8 0.0 1.2 0.0 0.5 10.7 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.7 0.1 1.2 0.0 0.3 0.1 0.1 0.3 2.3 0.3 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.4 0.4 14.2 14.1 14.0 18.0 14.1 19.3 19.6 15.7 19.2 16.0 18.7 14.9 1.9 0.0 0.0 0.3 0.0 0.8 0.2 0.5 0.0 3.8 0.2 0.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.4 0.5 0.2 0.0 0.7 0.0 0.0 1.7 0.4 0.1 0.4 0.0 0.1 0.0 0.1 0.4 0.1 0.6 0.0 0.8 0.0 0.0 0.0 0.4 1.5 0.6 0.3 0.0 1.9 0.1 1.4 0.0 0.0 0.3 1.2 0.0 0.4 0.0 0.3 0.0 0.0 0.6 0.5 0.0 1.1 1.0 2.6 3.2 0.0 0.9 0.1 0.2 0.1 0.0 0.2 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TMSB4X "TB4X, TMSB4" ENSG00000205542 "Thymosin beta 4 X-linked" P62328 X 12975110-12977227 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 30742.3;Langerhans cells: 57681.0;monocytes: 48133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033806 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Vesicles, Cytosol" "CAB033806: AB_2256019" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.72e-2)" "unprognostic (3.27e-2)" "unprognostic (7.98e-3)" "unprognostic (1.71e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (6.20e-4)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (3.77e-2)" "unprognostic (1.98e-1)" 6173.6 4217.0 3255.7 5088.7 3773.0 8722.4 4452.0 3539.2 4521.9 3685.7 2999.1 4327.1 1776.8 3731.3 2877.9 2069.6 2709.3 4129.3 2652.4 3319.4 3573.5 3300.1 2360.4 6225.5 10448.1 4064.7 3620.0 2592.1 1852.6 483.2 1053.7 2450.2 4203.0 2335.6 3793.9 273.3 1886.8 2441.9 816.5 1962.4 3671.2 3340.7 4219.2 7935.5 4690.0 486.8 3591.8 6377.6 1648.7 1475.0 7233.8 5168.6 2907.2 4467.6 5980.6 4886.3 9387.7 14881.1 11264.5 12247.2 23.0 3083.9 8032.6 2344.3 4005.4 1016.1 4865.3 1417.1 2900.6 9443.7 4198.0 2564.2 1411.5 2072.7 3135.4 8343.4 80.9 1771.0 2621.8 12.9 2619.8 6994.8 14038.1 5755.3 2911.9 2781.9 2412.7 5704.5 14335.9 3714.1 230.0 22.0 8424.8 2121.5 8390.5 15083.5 3384.1 2853.1 3337.3 6352.0 3321.0 5858.5 14234.5 1720.4 994.2 422.9 4461.8 207.4 583.3 6898.2 5536.5 6961.4 11607.2 3383.5 1647.5 19441.4 3123.6 4432.5 3490.6 2774.8 5183.2 2860.5 2499.5 42940.3 34738.5 50992.6 21474.2 33907.1 18326.4 18757.1 23777.1 23343.2 31253.2 16919.4 19802.1 20330.2 35862.9 18444.5 37523.3 12797.6 34088.1 86809.5 3255.7 3773.0 3539.2 4521.9 3319.4 3573.5 4064.7 3620.0 4203.0 4219.2 3591.8 4467.6 6885.8 5253.2 4939.6 35.9 6293.8 8836.3 2708.7 10515.3 296.5 332.9 2318.3 1124.2 106.9 3484.4 8003.6 6882.2 22.9 283.0 9136.2 9016.2 2181.5 17304.6 142.1 2613.2 4698.0 9239.4 1765.0 1339.1 54.3 23029.4 511.7 4800.1 2728.9 5047.4 4380.4 4646.7 6638.0 1088.5 30742.3 62.2 81.0 4883.9 14806.8 20982.2 57681.0 343.6 3932.0 17648.1 6349.9 212.7 48133.8 86.7 20882.8 19.6 102.1 25113.5 5826.4 6035.9 2541.8 3272.5 6888.7 835.1 2596.4 99.4 5732.4 1018.2 5450.7 58.2 126.3 933.7 9528.5 454.8 12719.6 3874.8 3140.6 9064.0 TNFAIP8 "GG2-1, MDC-3.13, SCC-S2" ENSG00000145779 "TNF alpha induced protein 8" O95379 5 119268692-119399688 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.8" "Cell type enhanced" "Detected in many" "granulocytes: 211.8;Langerhans cells: 323.4;Syncytiotrophoblasts: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 155.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054434, HPA057089" Uncertain Enhanced Nucleoplasm No Yes 470000 "Cluster 2: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA054434: AB_2682487, HPA057089: AB_2683331" "prognostic favorable (2.45e-4)" "unprognostic (6.06e-2)" "unprognostic (9.81e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" "unprognostic (1.08e-1)" "unprognostic (2.86e-3)" "unprognostic (4.92e-1)" "unprognostic (1.55e-1)" "unprognostic (4.45e-2)" "unprognostic (5.81e-3)" "unprognostic (4.47e-1)" "unprognostic (1.16e-1)" "unprognostic (1.18e-2)" "unprognostic (1.88e-3)" "unprognostic (1.64e-1)" "unprognostic (1.73e-2)" 72.4 5.1 4.2 62.3 4.1 65.5 19.3 8.9 7.0 15.9 31.2 17.8 16.1 13.3 17.1 25.3 10.5 16.6 8.5 3.9 4.0 16.4 10.1 19.1 117.8 4.9 4.1 3.5 16.8 14.8 1.6 52.5 4.8 18.9 19.0 2.4 11.2 14.4 3.3 31.6 31.3 15.5 1.7 61.1 28.6 17.5 5.1 100.0 25.3 5.6 115.9 43.6 17.8 6.6 27.7 19.0 10.0 16.1 20.5 17.2 91.2 15.0 40.4 11.1 23.0 10.2 31.6 51.0 4.7 16.7 17.6 38.4 8.3 45.4 15.7 56.6 17.9 81.4 41.1 17.6 9.9 99.6 86.4 19.1 42.0 33.7 15.9 21.2 15.4 99.9 32.0 155.2 15.5 10.7 84.5 128.9 15.0 16.0 8.9 25.6 44.1 75.8 44.5 54.8 5.1 7.8 56.6 10.9 5.5 32.1 9.4 111.4 8.1 20.2 7.8 14.1 17.9 76.0 90.0 103.3 23.3 104.8 11.9 491.9 96.1 305.0 111.0 105.1 217.3 267.2 221.9 164.7 133.6 243.5 260.8 169.7 54.6 111.4 86.7 63.8 188.4 213.0 4.2 4.1 8.9 7.0 3.9 4.0 4.9 4.1 4.8 1.7 5.1 6.6 8.9 9.6 18.7 1.6 174.9 160.5 80.9 81.9 123.5 0.2 14.4 10.8 10.3 12.8 38.3 18.4 0.0 142.6 83.6 2.7 17.6 55.4 4.4 11.8 7.8 23.2 1.2 34.5 0.8 101.0 158.8 30.1 17.9 9.5 211.8 0.7 6.4 1.9 48.9 0.0 2.3 9.9 20.3 59.4 323.4 1.4 2.1 126.0 37.4 24.4 196.6 4.3 111.2 1.0 6.8 125.7 2.7 1.9 45.6 63.9 0.9 19.8 47.2 0.4 46.0 4.0 32.9 1.1 18.0 93.1 119.2 292.7 139.0 35.2 4.3 103.6 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TNFRSF13B "CD267, IGAD2, TACI" ENSG00000240505 "TNF receptor superfamily member 13B" O14836 17 16929816-16972118 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 18.9;lymphoid tissue: 33.0;skeletal muscle: 62.9" "Group enriched" "Detected in some" 4 "B-cells: 117.3;Plasma cells: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 41 "memory B-cell: 130.9;naive B-cell: 51.8" "Lineage enriched" "Detected in many" 59 "B-cells: 130.9" "Group enriched" "Detected in some" 9 "Karpas-707: 167.2;RPMI-8226: 106.7;U-266/70: 72.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030453 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "HPA030453: AB_10601700" "unprognostic (3.94e-5)" "unprognostic (1.11e-3)" "unprognostic (4.88e-2)" "unprognostic (4.30e-3)" "unprognostic (1.23e-4)" "unprognostic (2.16e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-2)" "unprognostic (1.61e-4)" "unprognostic (2.22e-1)" "unprognostic (9.78e-2)" "unprognostic (1.59e-5)" "unprognostic (1.20e-1)" "unprognostic (4.49e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" 0.4 0.1 0.3 8.9 0.4 1.1 0.7 0.0 0.5 0.3 0.0 3.4 4.1 0.1 0.0 1.3 0.4 0.5 5.3 0.1 0.3 0.3 0.3 0.8 17.3 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.9 0.4 2.5 0.3 2.1 0.3 62.9 0.0 18.9 0.1 0.2 33.0 5.2 0.1 0.4 2.0 0.5 0.0 21.6 2.6 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.2 106.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.6 0.0 13.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 130.9 0.0 0.0 0.0 51.8 0.0 0.1 0.5 0.0 0.0 0.0 2.2 2.7 0.3 0.4 0.0 0.5 0.1 0.3 0.4 0.3 0.9 0.2 0.4 1.2 0.0 0.0 0.0 0.0 117.3 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.1 0.0 0.0 0.4 1.1 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.5 32.0 0.0 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 143.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.6 0.0 6.2 0.0 0.0 0.0 TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 4 "Plasma cells: 449.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cell line enhanced" "Detected in some" "Karpas-707: 179.6;RPMI-8226: 296.0;U-266/70: 829.4;U-266/84: 453.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" 0.4 1.1 0.0 14.9 0.3 1.9 14.1 0.4 0.4 1.4 0.0 28.9 29.0 0.5 0.2 1.9 0.6 3.1 0.4 0.2 0.3 0.3 1.0 2.0 31.9 0.3 0.0 0.8 0.5 0.1 0.1 0.1 0.3 0.4 22.1 0.1 15.4 0.9 0.0 0.3 15.2 0.6 0.0 20.3 24.4 2.2 0.3 14.8 0.7 0.1 47.9 9.9 0.3 0.6 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.8 0.3 0.1 0.0 0.0 49.2 0.1 0.3 0.1 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 179.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.6 0.0 296.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 0.6 0.0 0.5 0.5 0.0 0.5 829.4 453.4 68.1 0.7 0.2 0.0 1.2 0.4 0.2 0.3 0.1 0.4 124.9 0.2 0.2 0.2 108.5 0.1 0.2 1.8 0.7 0.1 103.3 0.1 12.6 0.0 0.3 0.4 0.4 0.2 0.3 0.3 0.0 0.3 0.0 0.3 0.6 0.0 0.0 0.0 0.0 91.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 10.9 0.0 0.0 0.7 0.0 5.3 0.1 0.0 0.0 0.4 2.0 0.0 0.0 0.4 1.8 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 106.7 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 449.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.7 0.6 0.0 0.6 0.0 6.0 0.0 1.0 0.0 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.3" "Cell type enhanced" "Detected in some" "Adipocytes: 7.1;Early spermatids: 3.5;Kupffer cells: 5.3;Langerhans cells: 3.3;Late spermatids: 9.8;Macrophages: 5.8;monocytes: 5.1" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 96.6" "Lineage enriched" "Detected in many" 5 "monocytes: 96.6" "Cell line enriched" "Detected in some" 21 "HDLM-2: 552.9" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" 5.3 0.0 0.1 3.1 2.3 0.6 3.5 0.0 0.6 0.2 0.1 0.4 0.0 0.8 0.0 0.2 0.9 0.6 1.9 0.0 0.2 0.3 0.0 0.9 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.7 0.2 0.2 0.1 0.0 0.3 0.1 0.9 0.9 0.7 0.5 0.1 1.4 2.5 1.4 0.7 1.0 0.1 1.2 1.1 0.9 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.4 0.0 0.1 0.8 11.7 0.0 0.0 0.0 0.0 0.0 0.1 552.9 0.1 0.0 0.1 0.0 0.0 10.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.7 26.3 1.5 0.0 0.0 1.5 0.2 21.7 0.0 0.4 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 1.4 1.4 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 17.6 1.0 0.1 59.4 0.3 0.1 0.1 0.0 8.7 0.0 0.0 0.0 18.3 0.0 96.6 2.3 0.8 8.5 0.1 2.3 0.0 0.6 0.0 0.2 0.2 0.1 0.2 0.1 0.7 0.2 7.1 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.1 0.5 2.2 0.0 0.0 0.6 0.0 0.2 1.1 2.6 0.1 0.0 0.1 2.2 0.1 1.5 0.0 0.5 0.0 0.0 5.3 3.3 9.8 0.3 5.8 0.0 1.0 5.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 1.0 0.0 0.1 0.3 0.4 0.2 0.0 0.1 TNFSF8 "CD153, CD30LG" ENSG00000106952 "TNF superfamily member 8" P32971 9 114893343-114930595 "Cancer-related genes, CD markers, Predicted membrane proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.7;lymphoid tissue: 26.9" "Cell type enhanced" "Detected in some" "B-cells: 8.2;dendritic cells: 6.5;Kupffer cells: 6.5;Macrophages: 8.4;Microglial cells: 5.6;monocytes: 5.4;Plasma cells: 9.3;T-cells: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Daudi: 50.9;SuSa: 23.3;U-698: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (8.82e-2)" "unprognostic (6.56e-3)" "unprognostic (7.79e-2)" "unprognostic (6.05e-2)" "unprognostic (2.67e-1)" "unprognostic (5.58e-3)" "unprognostic (5.26e-3)" "unprognostic (1.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.24e-1)" "unprognostic (1.70e-1)" "unprognostic (2.02e-1)" "unprognostic (4.75e-2)" "unprognostic (3.01e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-2)" "unprognostic (1.82e-1)" 3.3 1.4 0.5 13.9 0.7 18.7 2.0 0.5 0.7 1.9 0.9 2.0 0.7 0.8 1.8 1.7 0.8 5.0 0.9 0.4 0.6 0.8 2.2 2.5 23.4 1.1 0.6 0.7 0.8 0.4 0.2 2.8 0.8 0.6 2.4 0.0 0.6 0.6 0.2 0.4 5.1 1.7 0.8 7.4 2.5 0.3 1.5 26.9 0.8 0.4 22.2 5.9 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 40.8 0.0 0.0 0.0 0.0 20.8 0.0 6.0 10.1 19.8 1.8 23.7 14.1 10.7 2.4 26.2 19.6 6.2 1.8 1.4 6.5 9.8 13.0 0.5 0.7 0.5 0.7 0.4 0.6 1.1 0.6 0.8 0.8 1.5 1.4 0.2 0.0 0.0 0.0 8.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.5 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.4 0.1 0.0 0.0 0.5 1.1 0.0 1.3 0.0 0.7 0.1 3.7 0.0 0.1 0.0 0.0 6.5 4.8 0.0 0.0 8.4 0.0 5.6 5.4 0.0 2.1 0.0 0.1 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.6 0.0 29.3 0.0 0.0 0.0 TNIP1 "ABIN-1, KIAA0113, NAF1, VAN" ENSG00000145901 "TNFAIP3 interacting protein 1" Q15025 5 151029945-151093577 "Human disease related genes, Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 265.5;Proximal enterocytes: 257.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 406.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037893, HPA037894, HPA071950" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA037893: AB_10672468, HPA037894: AB_2675723, HPA071950: AB_2686476" "prognostic favorable (5.69e-4)" "unprognostic (1.08e-1)" "unprognostic (1.10e-1)" "prognostic favorable (6.86e-5)" "unprognostic (7.45e-3)" "unprognostic (2.94e-1)" "unprognostic (5.35e-3)" "unprognostic (1.45e-2)" "unprognostic (2.82e-1)" "unprognostic (3.42e-1)" "unprognostic (2.25e-2)" "unprognostic (1.96e-1)" "unprognostic (7.68e-3)" "unprognostic (1.47e-1)" "unprognostic (4.69e-2)" "unprognostic (2.29e-1)" "unprognostic (9.84e-2)" 120.0 49.7 34.1 79.6 33.4 128.0 90.7 35.3 40.8 60.1 33.3 72.7 73.2 37.6 22.4 89.3 37.9 54.3 96.3 31.5 36.5 83.3 107.9 91.7 69.4 40.5 37.4 41.8 71.6 42.8 27.2 28.7 39.0 47.9 52.4 17.4 53.1 39.2 211.2 60.4 90.8 32.6 37.6 101.2 63.5 14.6 37.1 43.4 45.9 130.7 83.3 84.4 69.3 35.3 117.7 81.3 15.4 55.7 58.4 58.6 39.4 54.7 174.5 48.6 91.1 78.4 155.5 95.8 182.3 74.2 285.3 68.3 25.2 406.4 59.4 167.8 34.6 37.8 44.4 51.1 111.4 43.6 168.3 84.3 74.5 80.3 166.2 134.1 69.1 37.2 24.6 94.2 122.7 43.7 48.2 60.0 13.9 41.1 43.4 39.0 118.4 131.4 152.3 85.0 21.7 49.9 42.4 131.5 57.2 41.6 67.5 54.5 107.8 162.7 53.0 28.7 79.2 184.6 102.2 43.4 177.0 63.7 39.6 18.2 12.1 36.0 11.9 11.1 14.0 12.7 13.9 12.0 9.2 16.8 7.1 7.9 41.3 12.4 10.8 12.8 21.2 10.4 34.1 33.4 35.3 40.8 31.5 36.5 40.5 37.4 39.0 37.6 37.1 35.3 31.1 57.7 45.4 4.9 73.1 29.7 50.4 119.9 27.3 14.3 33.3 24.9 48.8 54.3 72.2 27.6 4.2 18.3 53.7 233.7 72.4 218.0 3.3 39.8 18.0 75.1 37.3 52.4 6.5 139.1 31.3 38.9 92.8 64.8 48.2 105.2 42.1 62.7 39.0 18.5 6.4 69.0 46.8 49.6 113.1 6.9 27.1 64.9 26.6 8.4 238.3 20.3 68.0 5.5 9.4 265.5 173.9 23.7 63.6 179.1 257.5 56.4 49.1 15.0 32.9 69.2 45.7 2.2 13.9 30.2 28.6 48.2 60.7 12.2 77.1 158.6 TNIP3 "ABIN-3, FLJ21162, LIND" ENSG00000050730 "TNFAIP3 interacting protein 3" Q96KP6 4 121131408-121227466 "Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.4;urinary bladder: 4.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.7;Distal enterocytes: 19.1;Early spermatids: 13.8;Late spermatids: 46.2;T-cells: 17.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 6.2" "Lineage enriched" "Detected in single" 10 "T-cells: 6.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.4;hTEC/SVTERT24-B: 8.0;U-138 MG: 30.9;U-266/70: 8.8;U-266/84: 9.3;U-87 MG: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043063 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "HPA043063: AB_10793989" "unprognostic (2.89e-3)" "unprognostic (2.60e-1)" "unprognostic (5.23e-3)" "unprognostic (8.75e-5)" "unprognostic (9.62e-3)" "unprognostic (2.14e-2)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (2.80e-1)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.35e-2)" "unprognostic (2.84e-7)" "unprognostic (3.35e-2)" "unprognostic (6.51e-2)" "unprognostic (3.51e-1)" "unprognostic (8.78e-2)" 0.7 0.1 0.6 6.4 0.6 1.0 0.1 0.4 0.9 1.3 0.0 0.5 0.6 0.2 0.1 0.4 0.1 1.1 0.1 0.9 0.5 0.2 0.4 1.6 2.6 1.9 0.4 0.1 0.2 0.0 0.0 0.0 2.2 0.1 0.4 0.9 0.7 0.0 0.5 0.2 0.9 0.5 0.1 0.9 0.7 0.6 0.4 1.9 0.1 0.0 3.2 4.2 0.1 0.8 0.0 0.2 0.1 0.1 0.0 0.3 0.1 0.4 0.5 0.1 0.1 1.1 0.1 0.1 0.2 2.8 4.6 0.0 0.0 0.7 0.9 7.4 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.1 0.0 8.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 30.9 0.6 2.5 0.1 8.8 9.3 0.2 6.3 0.3 1.0 0.6 0.1 0.0 2.5 0.0 1.8 0.0 1.1 6.2 0.0 0.1 0.5 2.8 0.3 0.0 0.1 0.0 0.7 0.6 0.6 0.6 0.4 0.9 0.9 0.5 1.9 0.4 2.2 0.1 0.4 0.8 0.2 3.2 21.7 0.7 1.8 0.1 0.2 5.7 0.0 0.0 0.4 0.1 0.6 0.0 4.9 0.0 6.2 0.0 2.4 19.1 0.0 0.2 13.8 0.0 0.1 1.4 0.0 0.0 1.5 1.1 0.0 0.3 2.0 0.2 7.0 0.0 0.0 0.0 0.3 0.0 0.4 0.5 4.1 0.8 2.7 46.2 0.3 9.5 0.0 0.0 0.1 0.3 2.1 0.5 0.1 0.7 3.7 0.0 2.4 0.1 0.0 0.1 1.7 1.3 0.0 0.7 1.1 0.4 0.4 0.0 0.4 0.0 17.8 0.0 9.8 0.1 TNNI3K CARK ENSG00000116783 "TNNI3 interacting kinase" Q59H18 1 74235387-74544428 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 58.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 27.0;Early spermatids: 32.0;Late spermatids: 6.6;Proximal tubular cells: 8.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.0" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.04e-2)" "unprognostic (1.34e-2)" "unprognostic (3.83e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-1)" "unprognostic (3.40e-2)" "unprognostic (3.05e-1)" "unprognostic (2.48e-3)" "unprognostic (2.00e-1)" "unprognostic (9.66e-2)" "unprognostic (5.04e-2)" "unprognostic (1.80e-1)" "unprognostic (3.59e-3)" "unprognostic (4.88e-3)" "unprognostic (1.20e-1)" "unprognostic (8.80e-2)" "unprognostic (8.77e-2)" 1.8 1.4 3.6 0.3 3.6 0.1 1.4 4.9 7.2 1.0 2.0 2.0 0.4 1.3 2.5 0.6 1.5 0.4 58.7 3.7 3.9 3.4 0.4 0.9 0.4 3.3 3.2 1.5 0.4 0.7 2.3 0.0 3.6 1.1 0.5 5.2 0.8 0.4 1.5 1.6 0.8 0.9 3.5 1.4 1.1 4.0 3.5 0.4 1.0 0.6 0.5 1.4 0.9 4.8 0.0 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.6 3.6 4.9 7.2 3.7 3.9 3.3 3.2 3.6 3.5 3.5 4.8 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 1.2 0.2 0.3 27.0 0.0 0.1 1.8 0.0 0.0 0.0 0.1 1.9 0.1 32.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 6.6 0.9 0.2 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.0 8.0 0.1 0.5 0.0 0.6 0.8 0.5 1.4 0.0 0.3 0.1 0.1 0.0 0.0 0.2 TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.3;Hepatic stellate cells: 93.1;Leydig cells: 141.7;Peritubular cells: 114.0;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 114.2;ASC TERT1: 78.1;HHSteC: 59.9;HSkMC: 86.2;hTERT-RPE1: 61.9;TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034659: AB_10603349" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.21e-3)" "unprognostic (1.86e-1)" "unprognostic (3.59e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-2)" "unprognostic (8.97e-3)" "prognostic favorable (1.72e-4)" "prognostic favorable (9.32e-4)" "unprognostic (4.46e-2)" "unprognostic (1.09e-2)" "unprognostic (8.46e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" 156.3 66.9 59.3 14.8 66.2 0.3 121.6 46.4 57.8 121.2 33.3 79.0 14.4 98.8 14.0 28.3 121.0 32.5 99.6 43.7 49.2 67.3 66.5 83.4 15.8 58.0 63.5 104.1 34.6 17.0 43.3 33.1 54.0 66.3 11.5 6.0 35.7 41.1 69.0 42.1 56.7 28.5 50.8 79.5 58.2 15.9 58.3 7.2 80.6 58.8 6.4 82.6 81.1 57.9 2.0 21.2 2.7 2.2 114.2 78.1 0.7 11.8 27.1 6.2 3.2 1.4 5.7 0.1 25.3 32.1 2.6 1.5 0.1 7.8 2.4 0.5 0.8 0.4 25.5 11.3 59.9 0.3 0.5 86.2 0.3 7.9 4.7 61.9 36.3 0.4 0.6 0.3 24.9 5.1 0.2 0.4 1.9 1.4 5.8 0.7 6.6 0.3 8.2 0.4 1.2 2.7 4.4 2.4 8.8 1.6 26.1 0.7 52.1 12.9 14.8 4.7 2.0 0.6 0.3 0.1 20.4 0.3 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.3 66.2 46.4 57.8 43.7 49.2 58.0 63.5 54.0 50.8 58.3 57.9 109.3 3.2 25.7 33.3 0.5 0.0 6.8 0.0 5.2 21.1 15.1 13.0 7.9 10.0 2.5 5.5 0.0 0.5 0.9 0.4 3.9 5.8 2.8 4.4 41.1 69.6 1.2 2.7 3.1 4.4 0.4 40.5 2.0 14.5 0.0 7.7 93.1 37.5 2.4 30.3 7.8 3.9 0.0 4.4 0.0 7.2 141.7 2.9 0.0 31.9 0.1 29.6 0.0 46.3 35.6 2.4 9.0 114.0 1.8 4.5 2.1 2.6 1.5 11.3 151.2 51.3 64.7 4.2 4.4 1.3 0.0 0.8 1.4 2.6 1.8 2.1 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TOB2 "APRO5, bK223H9, TOB4, TOBL, TROB2" ENSG00000183864 "Transducer of ERBB2, 2" Q14106 22 41433494-41446801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016603, HPA054112" Approved Approved Cytosol NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA016603: AB_2669400, HPA054112: AB_2682385" "unprognostic (1.21e-3)" "unprognostic (3.10e-2)" "unprognostic (3.41e-1)" "prognostic favorable (3.08e-5)" "unprognostic (3.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.36e-1)" "unprognostic (5.36e-2)" "unprognostic (4.94e-2)" "unprognostic (5.74e-2)" "unprognostic (3.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.18e-6)" "unprognostic (1.50e-2)" "unprognostic (7.14e-2)" "unprognostic (1.85e-1)" "unprognostic (7.13e-2)" 46.1 31.3 39.3 15.6 56.3 9.7 25.5 78.1 40.1 26.5 18.5 30.1 22.4 25.0 11.8 26.6 38.4 28.8 41.2 39.3 43.8 24.6 27.1 20.7 18.5 61.7 42.9 38.0 29.0 35.6 22.8 22.0 44.0 26.6 15.5 55.0 17.2 19.4 86.5 27.1 23.9 20.1 39.5 20.6 30.5 13.6 52.0 19.6 36.1 68.1 19.7 23.3 21.0 71.9 36.8 16.6 28.5 19.4 65.4 45.5 27.5 23.9 36.7 29.8 26.2 21.9 17.0 22.4 23.5 34.8 11.6 31.4 26.7 13.4 27.1 23.0 34.2 12.3 23.9 33.4 44.8 33.5 15.9 42.1 22.5 35.6 15.4 30.1 30.2 7.6 18.9 24.5 24.6 40.8 13.9 19.2 24.4 48.1 17.6 29.7 19.2 19.4 21.3 25.3 13.1 8.8 60.0 32.2 44.6 17.7 17.9 16.5 37.9 29.3 27.1 23.0 22.7 22.9 10.7 12.2 17.8 14.2 19.7 3.9 5.9 4.1 7.5 8.0 7.1 10.0 6.2 6.3 5.3 7.5 3.2 4.7 3.8 3.8 8.4 8.0 5.5 6.1 39.3 56.3 78.1 40.1 39.3 43.8 61.7 42.9 44.0 39.5 52.0 71.9 48.5 48.1 59.6 48.6 61.4 126.8 66.6 24.3 105.3 56.0 83.1 56.9 59.8 58.6 31.7 47.8 64.6 34.7 56.9 76.9 23.5 29.7 41.1 88.6 59.3 45.3 54.3 16.8 12.2 19.1 37.3 54.1 42.3 116.9 34.1 13.7 52.5 29.7 19.6 25.2 15.1 67.7 10.2 22.0 117.9 61.6 66.8 51.4 53.4 14.0 34.6 58.3 18.6 10.1 43.6 32.3 60.0 82.0 26.2 73.6 103.6 29.2 45.9 105.2 52.6 97.4 60.9 23.8 28.9 88.7 136.7 63.3 57.4 19.6 61.9 92.2 TOR1AIP1 "FLJ13142, LAP1, LAP1B, LAP1C" ENSG00000143337 "Torsin 1A interacting protein 1" Q5JTV8 1 179882042-179920077 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 275.9;Late spermatids: 190.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047151, HPA050546, HPA070991" Enhanced Enhanced "Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "Nuclear membrane" "HPA047151: AB_2679956, HPA050546: AB_2681167, HPA070991: " "unprognostic (1.41e-1)" "unprognostic (3.95e-3)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (9.00e-2)" "unprognostic (6.33e-2)" "unprognostic (7.04e-2)" "unprognostic (8.62e-2)" "unprognostic (1.93e-1)" "unprognostic (9.10e-2)" "unprognostic (4.40e-2)" "unprognostic (4.41e-2)" "unprognostic (2.87e-1)" "unprognostic (7.75e-2)" "unprognostic (4.02e-2)" 39.7 34.8 20.4 27.2 23.6 84.5 33.9 22.4 25.0 42.6 29.0 46.5 15.9 40.5 35.9 40.6 31.6 34.3 38.5 18.1 21.4 36.5 38.4 35.5 34.2 23.6 23.3 54.5 27.9 36.9 20.1 28.5 22.0 43.8 22.8 25.1 31.5 43.2 54.1 20.1 23.6 41.0 21.2 35.0 31.3 27.0 21.5 27.5 46.8 74.8 27.6 40.4 26.4 24.5 37.1 36.4 24.9 32.3 109.7 73.6 47.7 48.2 57.7 44.5 45.6 28.5 68.5 9.7 52.1 50.2 31.8 63.5 23.6 39.6 52.8 62.9 23.2 26.4 31.5 28.5 50.4 90.8 78.4 57.8 29.8 55.3 51.3 50.1 40.9 39.5 39.2 47.6 47.9 33.1 37.4 28.5 35.5 47.9 13.9 22.8 38.9 25.5 43.7 71.3 20.9 29.2 60.7 57.9 83.6 36.6 44.3 91.9 41.9 60.7 26.5 42.0 58.8 53.4 75.3 19.5 23.6 49.3 95.1 177.7 86.0 205.3 76.4 94.8 89.6 54.9 68.9 76.8 90.8 66.7 71.0 73.1 132.8 74.6 127.5 65.1 81.9 115.5 20.4 23.6 22.4 25.0 18.1 21.4 23.6 23.3 22.0 21.2 21.5 24.5 42.4 32.1 36.1 21.2 33.9 43.3 64.4 21.3 48.3 11.8 27.5 17.8 30.2 18.6 24.2 20.2 16.7 16.2 44.1 13.1 13.7 20.5 275.9 25.9 30.9 33.6 20.3 25.2 13.6 25.2 26.0 51.7 23.4 48.4 36.1 19.8 36.8 27.4 27.6 6.7 16.9 10.6 20.3 48.5 26.1 190.0 47.5 40.4 14.2 21.5 36.6 40.5 35.0 15.6 26.9 29.0 12.5 58.6 32.8 48.4 11.1 19.2 29.2 13.6 26.3 72.5 38.0 14.0 20.4 38.1 37.5 18.2 47.5 23.6 8.3 54.0 TOX2 "C20orf100, dJ1108D11.2, GCX-1" ENSG00000124191 "TOX high mobility group box family member 2" Q96NM4 20 43914852-44069616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 50.2" "Cell type enhanced" "Detected in many" "Early spermatids: 22.3;Excitatory neurons: 20.5;Hepatic stellate cells: 34.2;Inhibitory neurons: 76.9;Oligodendrocyte precursor cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 92.0;U-266/70: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049900, HPA058396" Approved Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049900: AB_2680942, HPA058396: AB_2683704" "unprognostic (2.15e-2)" "unprognostic (1.82e-2)" "unprognostic (8.97e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (7.53e-3)" "unprognostic (6.29e-2)" "unprognostic (1.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (7.45e-8)" "unprognostic (1.60e-1)" "unprognostic (2.00e-1)" "unprognostic (7.60e-2)" "unprognostic (3.12e-1)" 10.0 4.0 11.2 6.2 8.2 1.8 6.8 4.9 18.4 10.2 2.3 7.6 1.3 6.2 1.1 12.8 3.6 2.9 3.6 8.3 35.7 5.1 5.2 36.4 13.3 12.3 18.8 3.1 2.0 10.1 24.6 2.6 15.9 16.7 2.4 1.9 3.8 2.7 1.5 5.1 10.2 1.6 5.8 5.7 9.7 20.8 25.9 50.2 7.4 6.4 8.1 17.6 8.9 10.6 9.9 12.5 4.9 0.9 4.7 13.3 0.1 11.5 5.3 8.1 8.9 0.0 4.0 0.0 16.8 16.6 35.2 5.1 3.2 0.3 8.4 15.5 2.7 0.0 1.1 0.0 92.0 0.1 19.4 31.0 14.0 27.0 1.6 25.8 9.4 9.5 0.0 14.5 4.6 11.3 3.2 4.5 3.0 0.3 42.2 0.0 10.1 15.4 0.0 1.2 4.3 35.8 2.4 0.0 18.0 0.5 0.0 9.2 11.3 0.0 7.5 0.3 0.1 57.4 13.5 9.0 16.9 0.1 27.0 0.0 0.2 6.5 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.7 1.1 0.0 2.6 1.2 0.1 11.2 8.2 4.9 18.4 8.3 35.7 12.3 18.8 15.9 5.8 25.9 10.6 8.0 0.0 0.6 3.9 3.4 1.0 1.0 0.7 0.0 0.8 0.2 0.1 0.8 1.5 0.1 0.0 0.0 0.0 7.3 0.3 0.0 0.1 22.3 0.3 8.9 8.9 0.0 0.0 20.5 0.2 0.1 6.7 1.5 0.3 0.0 10.7 34.2 0.5 1.5 3.3 76.9 0.6 0.0 2.9 3.6 17.3 1.8 1.2 1.8 3.7 0.2 4.6 1.0 45.2 0.5 0.1 2.2 0.7 12.1 0.5 0.0 0.1 0.0 0.1 0.0 0.4 8.7 1.3 1.8 0.2 1.3 0.3 10.5 0.1 1.8 0.3 TOX3 "CAGF9, TNRC9" ENSG00000103460 "TOX high mobility group box family member 3" O15405 16 52436417-52547802 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;retina: 17.6;stomach 1: 20.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.9;Enteroendocrine cells: 61.7;Inhibitory neurons: 138.9;Muller glia cells: 162.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 46.1;HAP1: 22.1;Hep G2: 20.8;OE19: 25.8;RT4: 97.1;SCLC-21H: 30.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040240, HPA040376" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm Cytosol "HPA040240: , HPA040376: AB_10795522" "unprognostic (1.14e-2)" "unprognostic (9.75e-3)" "unprognostic (9.08e-3)" "unprognostic (3.32e-2)" "unprognostic (3.50e-1)" "unprognostic (2.31e-1)" "unprognostic (4.74e-3)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.94e-2)" "unprognostic (2.59e-1)" "unprognostic (4.60e-3)" "prognostic favorable (3.08e-12)" "unprognostic (1.19e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.95e-4)" 0.4 3.0 4.7 1.4 5.6 0.0 3.8 1.2 6.0 7.6 0.3 15.6 9.3 1.3 4.4 0.6 3.1 6.9 0.0 5.3 4.4 9.5 5.2 1.4 0.1 4.6 3.5 0.9 2.6 0.0 2.3 0.2 3.0 1.8 17.9 17.6 8.9 0.5 4.0 0.7 9.3 1.0 5.1 0.0 20.3 0.6 8.4 1.3 0.0 0.5 0.2 5.7 1.0 6.8 0.0 5.8 46.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 3.5 0.0 0.3 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 25.8 0.0 0.0 8.0 0.2 10.7 97.1 30.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 5.6 1.2 6.0 5.3 4.4 4.6 3.5 3.0 5.1 8.4 6.8 0.2 6.4 8.2 1.3 0.0 1.0 0.5 2.8 0.6 4.1 20.0 12.6 0.7 52.9 7.7 35.0 0.0 0.0 0.0 47.6 3.9 1.6 3.2 1.6 0.4 0.3 61.7 0.0 3.9 5.1 0.0 1.5 29.6 6.1 0.0 0.1 0.7 4.6 0.1 40.4 138.9 31.7 2.0 0.0 0.3 1.8 0.6 0.2 0.0 8.4 0.0 162.1 0.0 51.8 75.0 15.3 15.2 0.0 0.2 11.8 16.6 14.0 12.3 3.8 0.0 3.3 0.8 0.1 0.8 0.3 0.3 0.0 0.4 9.7 32.6 6.5 TP53I13 DSCP1 ENSG00000167543 "Tumor protein p53 inducible protein 13" Q8NBR0 17 29566052-29573157 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 110.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.93e-1)" "unprognostic (4.90e-2)" "unprognostic (2.50e-3)" "unprognostic (9.31e-3)" "unprognostic (4.94e-3)" "unprognostic (1.05e-2)" "unprognostic (2.17e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (5.47e-2)" "prognostic favorable (3.13e-5)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (2.92e-2)" 71.2 34.7 19.5 30.3 20.4 37.4 58.5 18.6 28.3 41.8 26.2 50.0 45.1 36.8 5.6 31.1 35.5 19.5 53.1 17.7 18.7 68.2 111.3 50.2 42.4 23.6 21.3 33.1 47.2 15.7 91.8 13.5 21.8 43.1 8.9 1.5 35.6 14.4 30.1 29.0 79.1 10.3 19.6 78.1 48.1 60.5 21.0 11.7 58.0 11.0 16.2 41.9 38.6 22.4 27.9 73.9 22.2 64.0 37.0 25.4 41.0 45.6 20.5 27.2 29.2 31.3 11.1 19.3 49.1 27.9 38.5 66.8 10.4 13.4 3.9 84.2 41.3 11.8 85.0 29.0 33.0 19.7 34.5 21.9 19.0 23.9 8.4 18.5 16.6 39.6 17.3 34.8 12.1 45.4 48.7 79.1 9.8 32.4 28.1 91.0 53.4 69.0 24.9 17.8 10.0 32.5 56.9 21.0 22.4 8.1 60.7 81.5 19.1 26.9 40.6 28.9 36.2 71.7 33.9 15.8 47.5 11.9 32.4 52.6 11.2 20.8 26.5 14.5 26.4 24.1 25.4 20.1 26.0 23.4 19.8 17.9 0.9 28.8 9.7 110.9 25.0 13.6 19.5 20.4 18.6 28.3 17.7 18.7 23.6 21.3 21.8 19.6 21.0 22.4 19.5 0.0 3.0 16.3 31.2 13.8 42.4 48.1 25.6 0.8 28.2 38.9 28.1 12.8 23.2 40.5 6.2 50.8 47.7 30.2 7.9 33.9 17.9 19.7 32.4 14.1 19.9 9.0 5.6 28.7 40.0 47.5 30.1 28.1 15.9 33.9 13.2 22.1 27.4 6.7 4.0 28.6 24.4 10.7 31.2 8.4 34.5 28.9 30.2 18.7 23.1 20.0 12.3 3.5 5.6 27.4 31.7 18.8 31.8 30.6 51.9 17.7 16.2 9.0 19.7 31.9 26.0 87.8 33.4 13.9 7.4 22.6 30.4 23.9 27.1 37.6 TPM4 ENSG00000167460 "Tropomyosin 4" P67936 19 16067021-16103002 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1297.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 2111.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004685, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 370000000 "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Actin filaments" Cytosol "CAB004685: AB_425723, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.27e-1)" "unprognostic (1.53e-2)" "unprognostic (3.62e-3)" "unprognostic (7.38e-3)" "unprognostic (3.80e-1)" "unprognostic (2.40e-2)" "unprognostic (3.11e-2)" "unprognostic (2.75e-3)" "unprognostic (1.38e-2)" "unprognostic (3.61e-1)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.26e-10)" "unprognostic (3.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" 324.1 109.9 24.7 186.3 26.3 33.8 269.0 42.1 40.4 342.4 23.4 255.0 64.6 455.0 10.6 401.8 310.0 144.8 189.6 23.2 27.0 168.1 54.1 374.1 78.2 30.7 28.7 293.8 77.9 23.6 93.4 170.7 31.9 212.1 39.2 3.6 267.2 140.4 50.3 241.4 153.8 190.4 29.1 244.1 201.4 66.2 36.6 32.4 119.4 19.3 68.5 287.5 333.8 27.8 614.5 275.2 194.7 190.9 701.3 728.2 725.6 1082.9 470.3 356.4 357.7 325.5 473.5 31.1 724.2 492.9 383.9 331.6 72.9 386.7 141.6 503.8 138.8 305.4 270.2 232.3 357.0 52.3 728.3 715.2 94.0 327.6 331.1 353.2 427.2 115.7 46.2 217.9 360.8 290.2 152.4 233.0 227.1 461.2 380.4 201.4 413.2 143.4 87.3 387.9 75.3 315.3 670.4 155.5 298.8 90.6 5.3 60.8 1237.2 954.1 166.8 2111.0 875.3 82.4 167.3 142.5 651.4 144.5 337.0 130.8 81.4 5.9 96.0 93.9 71.4 59.6 69.0 84.3 96.6 53.0 18.6 47.2 82.1 75.2 50.4 76.8 151.0 158.4 24.7 26.3 42.1 40.4 23.2 27.0 30.7 28.7 31.9 29.1 36.6 27.8 389.4 400.6 156.6 9.4 148.6 431.1 1297.2 175.2 273.8 45.9 194.3 189.4 49.1 120.1 297.0 242.8 10.4 263.5 205.6 298.4 13.7 717.1 67.3 159.0 506.6 425.5 94.0 33.4 23.8 571.6 852.9 345.1 303.7 305.0 249.6 170.8 288.8 4.2 336.8 5.0 19.0 215.8 101.7 112.0 368.8 54.8 173.1 433.2 142.3 26.2 249.5 7.5 132.8 13.6 48.5 1017.2 258.8 547.2 310.9 900.2 61.2 29.0 133.1 11.7 335.2 170.0 516.6 29.5 10.1 328.2 343.8 568.9 192.0 222.3 162.7 1025.0 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240379-1242554 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "granulocytes: 5873.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 893 "basophil: 89.3" "Lineage enriched" "Detected in single" 893 "granulocytes: 89.3" "Cell line enriched" "Detected in some" 166 "HMC-1: 3813.2" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB016369: AB_628406, CAB022175: , HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favorable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 96.6 2.9 0.3 23.6 0.5 2.4 47.2 0.3 0.9 53.7 0.9 83.0 71.6 73.3 6.0 64.3 26.6 129.7 14.7 0.4 0.4 13.9 12.2 128.5 21.3 0.4 0.3 3.2 18.9 2.3 3.5 1.2 0.6 65.9 34.6 0.0 60.2 22.5 10.1 122.7 148.7 17.9 0.4 5.9 104.0 8.9 0.4 14.2 4.7 13.0 13.2 113.5 52.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 1.3 3813.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.3 2.1 6.1 0.5 0.4 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.1 1.1 0.0 0.0 2.8 22.9 2.0 89.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.5 0.3 0.9 0.4 0.4 0.4 0.3 0.6 0.4 0.4 0.3 0.0 25.6 135.5 0.0 2.9 18.6 5.1 0.0 1.2 0.0 0.9 0.1 0.3 0.0 8.1 0.0 0.0 0.0 0.2 0.9 0.0 1.2 0.3 0.0 0.0 4.1 0.0 3.8 0.0 0.0 0.2 7.6 0.5 0.0 5873.9 0.0 0.0 0.3 5.2 0.0 0.0 0.0 0.0 0.3 25.6 0.2 0.0 7.7 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 11.7 4.0 0.4 0.1 5.1 0.0 0.0 0.3 3.2 0.0 0.1 0.1 9.9 0.3 440.9 0.0 0.5 5.6 TPSG1 "PRSS31, TMT" ENSG00000116176 "Tryptase gamma 1" Q9NRR2 16 1221651-1225257 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 14.7" "Cell type enriched" "Detected in some" 6 "Intestinal goblet cells: 278.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.2" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HMC-1: 23.2;MCF7: 7.9" "Not detected" "Not detected" HPA060458 Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA060458: AB_2684283" "unprognostic (1.86e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-3)" "unprognostic (1.27e-1)" "unprognostic (5.58e-2)" "unprognostic (1.18e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-2)" "unprognostic (9.97e-2)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (1.76e-8)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (8.65e-4)" "unprognostic (5.70e-2)" 0.7 1.0 0.4 1.4 1.6 0.0 3.2 0.0 0.4 0.7 0.0 14.7 14.1 1.3 0.1 0.8 0.7 1.0 0.3 0.2 0.4 1.2 0.4 0.8 0.0 0.1 0.1 2.1 0.2 0.0 3.1 0.0 0.3 1.1 9.0 0.1 0.3 0.2 0.2 1.2 9.3 0.3 0.1 0.0 1.1 1.6 0.5 0.0 0.1 0.0 0.0 1.8 0.8 0.0 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.4 0.2 0.4 0.1 0.1 0.3 0.1 0.5 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.2 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.9 0.0 0.0 0.4 0.0 0.0 0.0 278.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.3 0.1 5.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 4.7 0.0 TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 76.5;Excitatory neurons: 101.9;Inhibitory neurons: 107.1;Spermatocytes: 97.1" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.2;neutrophil: 35.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" 16.9 15.8 22.1 10.8 20.5 6.0 13.4 18.4 21.6 35.4 12.3 11.1 3.2 21.8 14.3 10.8 11.2 38.1 8.5 19.4 36.7 23.1 46.0 11.5 5.9 37.2 25.0 13.5 7.8 11.0 19.5 26.4 24.7 15.1 8.0 5.2 6.8 16.4 2.7 8.2 8.7 16.2 22.9 12.0 10.9 23.0 33.8 2.1 11.3 5.6 5.3 36.8 22.1 22.5 12.1 6.5 16.5 22.4 52.7 42.0 5.7 22.3 49.8 25.7 37.1 21.9 6.6 1.4 17.7 45.1 38.9 8.9 16.2 24.8 33.3 3.5 9.3 2.3 15.1 16.5 62.3 1.8 1.9 59.5 19.0 50.2 22.1 27.8 32.7 2.9 1.0 10.2 40.2 6.2 0.1 3.1 15.5 0.4 9.6 7.8 14.6 11.4 27.3 11.5 10.4 44.5 27.8 2.1 62.2 32.4 8.6 4.7 62.3 33.1 21.3 24.2 40.6 9.2 13.3 4.7 29.6 6.8 48.2 52.2 2.3 23.9 0.8 0.1 0.8 6.1 0.5 0.6 0.3 14.0 2.2 4.1 35.2 8.8 0.0 0.0 0.0 1.9 22.1 20.5 18.4 21.6 19.4 36.7 37.2 25.0 24.7 22.9 33.8 22.5 33.8 0.0 8.9 38.8 11.5 10.8 7.7 24.4 33.6 8.5 4.0 13.3 1.6 5.7 9.6 31.3 2.1 1.8 3.8 0.2 9.8 23.0 11.2 13.3 76.5 17.9 7.7 1.3 101.9 47.6 4.3 58.5 12.2 9.7 4.5 12.2 10.0 34.1 16.2 6.7 107.1 0.8 8.2 8.9 8.9 11.6 48.1 6.2 14.2 32.8 15.8 5.0 1.0 61.3 38.8 23.7 0.1 37.2 7.1 5.3 0.0 3.2 19.5 3.6 6.6 16.4 21.6 97.1 41.3 15.1 7.5 3.8 2.8 12.6 0.7 7.7 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 398.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.0;NK-cells: 263.7;Plasma cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" NA NA 88000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 24.4 31.0 24.4 15.2 20.8 23.1 21.8 19.1 29.9 17.4 26.9 11.5 13.6 18.0 111.6 18.7 17.0 12.2 27.5 23.4 22.9 24.9 74.9 45.7 19.1 22.0 24.2 9.2 398.8 5.3 9.9 41.8 20.8 16.0 8.8 3.3 10.9 17.8 38.5 18.4 13.4 12.1 23.1 36.4 11.7 20.6 34.2 10.7 38.8 22.6 17.0 17.1 17.3 20.7 12.8 9.1 11.7 6.0 24.4 18.7 16.4 27.9 49.9 22.2 20.3 6.2 6.5 21.4 7.3 50.4 11.6 19.5 8.8 19.2 12.7 8.8 16.9 51.8 5.6 13.1 10.2 6.0 158.7 20.1 30.3 22.5 7.7 22.5 41.6 9.6 52.6 65.2 17.2 14.3 24.3 40.7 15.4 10.0 9.1 22.5 15.8 60.2 6.7 14.3 8.8 6.1 12.9 11.2 16.0 17.0 5.2 24.7 33.2 27.3 61.2 22.5 27.3 20.9 31.5 20.6 20.7 23.1 25.3 490.4 77.0 111.9 249.2 86.3 70.5 23.6 57.0 187.2 48.3 25.6 27.8 163.6 163.0 354.9 94.3 115.3 71.9 240.7 24.4 20.8 19.1 29.9 23.4 22.9 22.0 24.2 20.8 23.1 34.2 20.7 37.3 16.0 12.6 13.7 30.8 38.1 82.5 29.9 14.2 9.0 10.8 13.1 15.5 47.1 14.4 22.0 6.2 171.0 120.8 6.7 27.4 12.9 15.2 31.1 14.8 66.1 0.0 64.6 23.4 65.1 49.8 10.7 5.1 39.5 53.7 13.9 113.6 79.3 123.9 6.7 20.3 9.3 12.2 55.9 48.6 4.5 5.3 70.1 28.4 47.8 32.4 1.9 263.7 5.0 1.9 53.1 8.7 4.1 183.7 36.4 16.5 7.6 18.6 5.3 6.6 9.9 15.3 2.9 13.2 15.1 35.9 143.0 64.4 42.0 11.8 83.7 TRAC ENSG00000277734 "T cell receptor alpha constant" 14 22547506-22552156 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 7 "lymphoid tissue: 787.9" "Cell type enhanced" "Detected in many" "dendritic cells: 166.3;Rod photoreceptor cells: 75.9;T-cells: 428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "MAIT T-cell: 2123.1;memory CD4 T-cell: 2939.7;memory CD8 T-cell: 2508.6;naive CD4 T-cell: 2671.8;naive CD8 T-cell: 2388.0;T-reg: 4379.2" "Lineage enriched" "Detected in all" 41 "T-cells: 4379.2" "Cell line enhanced" "Detected in many" "HDLM-2: 127.0;JURKAT: 294.7;NB-4: 83.1;U-266/84: 126.2;U-698: 62.1" "Low region specificity" "Detected in all" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "prognostic favorable (3.21e-4)" "prognostic favorable (4.87e-6)" "unprognostic (9.92e-3)" "prognostic favorable (4.15e-6)" "unprognostic (3.71e-2)" "prognostic favorable (5.25e-5)" "unprognostic (2.83e-2)" "unprognostic (9.81e-3)" "unprognostic (2.51e-3)" "unprognostic (1.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.99e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (2.13e-1)" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (2.75e-2)" 17.5 7.7 5.4 157.5 14.8 29.5 16.9 6.9 3.9 12.0 2.4 33.6 46.6 9.3 39.3 17.2 10.0 42.2 45.3 2.0 2.0 10.5 16.5 47.0 394.3 3.4 8.2 7.3 3.3 1.9 11.4 2.3 4.0 15.3 43.4 112.7 25.8 5.5 3.3 19.5 78.3 10.4 2.5 134.1 54.9 7.2 2.2 787.9 12.2 2.7 287.6 58.4 9.7 2.3 0.3 0.0 11.6 0.0 0.0 0.0 0.2 0.1 0.4 0.3 0.4 1.8 0.0 11.4 1.5 0.0 0.2 0.0 0.2 0.1 1.1 127.0 0.0 0.2 0.0 0.0 0.0 16.4 0.8 0.0 0.0 4.3 0.2 0.0 3.1 294.7 0.4 0.1 1.2 0.0 45.7 83.1 3.1 0.1 0.6 22.9 2.8 0.2 0.7 0.0 0.0 0.2 0.0 0.0 1.1 1.7 0.0 1.6 8.3 3.4 0.7 0.3 1.0 2.7 126.2 62.1 1.0 0.5 0.1 24.5 10.2 9.8 520.5 6.7 2123.1 105.6 2939.7 2508.6 7.9 94.6 2671.8 2388.0 57.7 89.7 11.0 11.8 4379.2 2965.8 5.4 14.8 6.9 3.9 2.0 2.0 3.4 8.2 4.0 2.5 2.2 2.3 9.0 3.2 25.6 0.0 46.3 0.0 1.0 0.0 5.7 9.0 4.9 8.5 35.7 0.0 6.2 0.0 12.5 0.2 166.3 0.9 17.6 0.7 46.2 0.9 0.6 3.3 0.0 16.4 0.0 0.0 0.2 15.9 4.1 0.5 10.1 0.0 9.3 1.4 1.3 0.0 0.0 0.9 0.0 8.1 0.0 4.8 1.8 12.2 0.0 0.0 20.2 11.8 44.3 0.0 0.0 0.1 1.2 5.3 25.4 0.2 0.5 4.6 0.0 75.9 0.0 2.6 4.7 2.2 0.8 5.4 0.0 0.3 428.0 0.0 0.7 0.2 TRARG1 "BEC-1, DSPB1, IFITMD3, LOST1, TUSC5" ENSG00000184811 "Trafficking regulator of GLUT4 (SLC2A4) 1" Q8IXB3 17 1279662-1300978 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "adipose tissue: 101.4;breast: 68.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 294 "ASC diff: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050825 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050825: AB_2681252" "unprognostic (5.84e-2)" "unprognostic (7.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (2.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (1.90e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (5.10e-1)" 101.4 1.1 0.0 1.2 0.0 0.0 68.7 0.0 0.4 0.4 0.0 1.2 0.0 0.2 0.0 0.1 0.1 0.6 1.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 1.2 2.1 2.3 0.0 0.0 0.0 0.6 0.6 0.0 0.1 1.0 0.6 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 79.8" "Cell type enriched" "Detected in some" 10 "T-cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 395.1" "Group enriched" "Detected in many" 155 "granulocytes: 395.1;T-cells: 313.1" "Group enriched" "Detected in some" 25 "JURKAT: 29.9;MOLT-4: 76.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" 1.1 0.6 0.0 11.0 0.0 2.7 0.8 0.0 0.0 0.4 0.0 1.3 1.4 0.4 0.4 1.0 0.3 2.5 0.4 0.1 0.0 0.3 1.3 2.1 23.9 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.8 1.5 0.0 0.6 0.1 0.1 0.6 3.0 0.5 0.0 8.5 2.4 0.4 0.0 79.8 0.4 0.4 12.4 2.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 2.1 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 395.1 0.6 0.2 57.0 0.2 116.4 1.0 229.5 119.6 0.3 0.4 313.1 77.7 3.5 2.2 0.7 0.8 111.1 139.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.0 3.3 8.4 0.1 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 1.8 0.0 0.0 8.9 0.1 0.0 0.0 2.3 0.1 0.1 1.1 0.0 2.7 0.1 0.0 0.0 1.7 7.7 0.1 2.5 0.0 1.8 0.6 0.2 0.0 0.2 0.0 0.0 1.0 12.2 2.2 0.0 1.8 3.6 0.0 3.2 0.0 3.1 0.0 0.2 0.0 0.0 0.0 5.1 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.0 8.0 0.1 129.3 0.6 0.0 0.2 TRAV1-2 ENSG00000256553 "T cell receptor alpha variable 1-2" A0A0B4J238 14 21642889-21643578 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 19.3" "Cell type enriched" "Detected in single" 6 "T-cells: 4.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "MAIT T-cell: 2027.8" "Lineage enriched" "Detected in many" 507 "T-cells: 2027.8" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.19e-3)" "unprognostic (1.29e-3)" "unprognostic (1.59e-2)" "unprognostic (1.84e-3)" "unprognostic (5.87e-3)" "unprognostic (1.55e-3)" "unprognostic (3.56e-2)" "unprognostic (8.90e-2)" "unprognostic (6.50e-4)" "unprognostic (3.16e-1)" "unprognostic (1.68e-1)" "unprognostic (1.13e-2)" "unprognostic (2.15e-1)" "unprognostic (1.43e-1)" "unprognostic (8.99e-2)" "unprognostic (8.30e-2)" 0.3 0.7 0.0 4.5 0.0 1.3 0.4 0.0 0.4 0.6 0.0 1.2 1.6 0.3 0.3 0.5 0.7 3.1 0.1 0.0 0.0 0.2 1.1 2.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 1.1 0.0 0.3 0.0 0.0 0.4 1.3 0.3 0.1 4.6 1.5 0.1 0.0 19.3 0.5 0.0 7.2 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 0.7 1.0 0.6 2027.8 0.4 44.9 311.2 0.8 0.2 40.9 70.0 3.9 0.3 1.3 1.7 79.5 40.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 TRAV12-1 ENSG00000211785 "T cell receptor alpha variable 12-1" A0A0B4J245 14 21841240-21841774 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 21.1" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 4.1;Plasma cells: 1.4;T-cells: 6.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 72 "MAIT T-cell: 128.5;memory CD4 T-cell: 205.2;memory CD8 T-cell: 199.7;naive CD4 T-cell: 138.6;naive CD8 T-cell: 251.7;T-reg: 193.9" "Lineage enriched" "Detected in many" 97 "T-cells: 251.7" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (4.83e-3)" "unprognostic (9.56e-5)" "unprognostic (2.18e-2)" "unprognostic (3.33e-3)" "unprognostic (8.05e-2)" "unprognostic (2.99e-4)" "unprognostic (3.16e-4)" "unprognostic (3.23e-2)" "unprognostic (1.77e-3)" "unprognostic (1.15e-1)" "unprognostic (6.92e-2)" "unprognostic (3.97e-4)" "unprognostic (1.39e-1)" "unprognostic (7.99e-2)" "unprognostic (2.14e-1)" "unprognostic (2.92e-2)" 0.5 0.0 0.0 6.5 0.0 1.2 1.3 0.0 0.2 0.6 0.0 1.3 2.8 0.4 0.8 0.7 0.4 2.5 0.1 0.0 0.0 0.1 0.5 1.3 13.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.0 0.2 0.0 0.4 0.0 2.3 1.2 0.0 4.9 1.9 0.1 0.0 21.1 0.2 0.2 14.3 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.9 1.9 0.4 128.5 0.2 205.2 199.7 0.3 0.6 138.6 251.7 2.6 0.3 1.0 0.2 193.9 100.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 TRAV12-2 ENSG00000211789 "T cell receptor alpha variable 12-2" A0A075B6T6 14 21887857-21888502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 22.4" "Cell type enriched" "Detected in some" 6 "T-cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "memory CD4 T-cell: 101.9;memory CD8 T-cell: 87.7;naive CD4 T-cell: 90.3;naive CD8 T-cell: 65.2;T-reg: 143.3" "Lineage enriched" "Detected in many" 77 "T-cells: 143.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.74e-2)" "unprognostic (4.98e-3)" "unprognostic (4.75e-2)" "unprognostic (2.41e-4)" "unprognostic (2.22e-2)" "unprognostic (7.44e-2)" "unprognostic (5.23e-4)" "unprognostic (1.73e-3)" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.03e-3)" "unprognostic (3.69e-1)" "unprognostic (3.34e-3)" "unprognostic (9.87e-2)" "unprognostic (3.01e-2)" 0.8 0.8 0.0 7.5 0.0 0.9 1.0 0.0 0.1 1.0 0.0 1.6 4.1 0.8 0.5 0.8 1.2 2.5 0.3 0.0 0.0 0.3 0.6 2.5 15.7 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.2 0.8 2.1 0.0 1.7 0.1 0.2 0.5 2.9 0.5 0.0 5.9 2.3 0.0 0.0 22.4 0.6 0.0 13.5 3.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.2 0.0 5.7 0.1 101.9 87.7 0.2 0.1 90.3 65.2 1.8 0.1 0.2 0.1 143.3 27.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 TRAV12-3 "TCRAV12S3, TCRAV2S2, TRAV123" ENSG00000211794 "T cell receptor alpha variable 12-3" A0A0B4J271 14 21965451-21966061 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 60.3" "Group enriched" "Detected in some" 4 "Erythroid cells: 1.7;T-cells: 6.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 186.5;T-reg: 256.6" "Lineage enriched" "Detected in many" 23 "T-cells: 256.6" "Cell line enriched" "Detected in single" 43 "JURKAT: 4.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.62e-4)" "unprognostic (7.68e-4)" "unprognostic (5.17e-2)" "unprognostic (1.33e-3)" "unprognostic (2.32e-1)" "unprognostic (1.80e-3)" "unprognostic (2.50e-2)" "unprognostic (1.17e-1)" "unprognostic (7.55e-4)" "unprognostic (9.00e-3)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (4.52e-5)" "unprognostic (3.75e-1)" "unprognostic (4.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.68e-2)" 0.5 0.1 0.0 9.3 0.0 1.5 1.1 0.0 0.1 1.7 0.0 2.1 2.2 0.6 0.9 0.4 0.6 6.1 0.5 0.0 0.0 0.3 0.4 2.8 18.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 3.2 0.0 0.3 0.2 0.1 0.4 2.7 0.5 0.0 4.6 1.9 0.1 0.0 60.3 0.2 0.0 17.4 3.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.5 0.2 0.4 0.2 12.7 0.4 186.5 57.4 0.4 1.8 119.7 153.3 4.6 0.9 0.7 0.5 256.6 48.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 TRAV13-1 ENSG00000211788 "T cell receptor alpha variable 13-1" A0A0B4J241 14 21868839-21869365 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 62.5" "Cell type enriched" "Detected in single" 26 "T-cells: 15.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 329.3" "Lineage enriched" "Detected in many" 28 "T-cells: 329.3" "Cell line enriched" "Detected in single" 20 "JURKAT: 1.9" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.10e-3)" "unprognostic (9.80e-3)" "unprognostic (1.60e-2)" "unprognostic (3.04e-3)" "unprognostic (5.71e-2)" "unprognostic (3.30e-5)" "unprognostic (7.68e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-2)" "unprognostic (1.15e-1)" "unprognostic (7.16e-5)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.20e-2)" "unprognostic (5.59e-2)" 1.1 0.3 0.0 13.7 0.1 2.2 1.1 0.0 0.2 0.2 0.0 3.7 3.6 0.7 0.3 0.8 0.9 3.7 0.5 0.0 0.0 0.4 1.0 4.4 29.2 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.0 1.1 3.0 0.0 1.2 0.4 0.2 0.2 7.5 0.4 0.0 8.4 3.8 0.2 0.0 62.5 0.6 0.7 29.9 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.7 0.4 1.4 0.4 62.6 0.4 203.8 179.6 0.5 0.6 232.3 292.5 6.2 0.5 0.5 0.9 329.3 80.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.6 0.0 0.0 0.0 TRAV13-2 ENSG00000211791 "T cell receptor alpha variable 13-2" A0A0B4J235 14 21918188-21918756 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "lymphoid tissue: 51.7" "Group enriched" "Detected in some" 4 "NK-cells: 4.1;T-cells: 5.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "MAIT T-cell: 32.9;memory CD4 T-cell: 94.0;memory CD8 T-cell: 57.3;naive CD4 T-cell: 101.8;naive CD8 T-cell: 114.1;T-reg: 114.8" "Lineage enriched" "Detected in many" 53 "T-cells: 114.8" "Cell line enriched" "Detected in some" 4 "JURKAT: 6.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.15e-3)" "unprognostic (1.47e-2)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" "unprognostic (5.58e-1)" "unprognostic (4.38e-4)" "unprognostic (1.08e-1)" "unprognostic (6.47e-2)" "unprognostic (2.85e-2)" "unprognostic (4.16e-2)" "unprognostic (2.12e-1)" "unprognostic (2.99e-1)" "unprognostic (3.66e-4)" "unprognostic (1.52e-1)" "unprognostic (9.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.77e-2)" 0.3 0.0 0.0 6.6 0.0 1.4 0.9 0.0 0.2 0.4 0.0 1.3 2.1 0.2 1.2 0.7 0.3 1.4 0.2 0.0 0.0 0.2 0.4 1.6 14.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1.0 0.0 0.5 0.1 0.1 0.5 1.6 0.5 0.1 4.6 1.9 0.2 0.0 51.7 0.2 0.0 10.0 1.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.1 2.2 0.2 32.9 0.4 94.0 57.3 0.1 0.2 101.8 114.1 2.1 0.6 0.2 0.3 114.8 40.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.7 0.0 0.0 0.0 TRAV14DV4 "hADV14S1, TCRAV6S1-hDV104S1, TRAV14/DV4" ENSG00000211792 "T cell receptor alpha variable 14/delta variable 4" A0A0A6YYC5 14 21924063-21924651 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 25.7" "Cell type enriched" "Detected in single" 12 "T-cells: 6.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 38.2;memory CD8 T-cell: 78.1;naive CD4 T-cell: 30.7;naive CD8 T-cell: 122.3;T-reg: 42.6" "Lineage enriched" "Detected in single" 176 "T-cells: 122.3" "Cell line enhanced" "Detected in single" "JURKAT: 1.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.82e-3)" "unprognostic (1.00e-2)" "unprognostic (1.43e-1)" "unprognostic (3.06e-3)" "unprognostic (3.00e-5)" "unprognostic (2.52e-1)" "unprognostic (7.61e-4)" "unprognostic (3.77e-1)" "unprognostic (2.82e-2)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (2.62e-5)" "unprognostic (3.01e-1)" "unprognostic (4.17e-2)" "unprognostic (2.90e-1)" "unprognostic (1.60e-2)" 0.6 0.1 0.0 4.2 0.0 1.5 0.6 0.0 0.1 0.5 0.0 0.8 2.0 0.3 0.0 0.6 0.6 1.6 0.2 0.0 0.0 0.2 1.1 2.5 12.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.1 0.0 0.2 1.7 0.1 0.0 3.4 1.3 0.0 0.0 25.7 0.2 0.0 8.0 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.2 9.9 0.1 38.2 78.1 0.0 0.2 30.7 122.3 0.3 0.4 0.3 0.0 42.6 21.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 TRAV16 "TCRAV16S1, TCRAV9S1" ENSG00000211796 "T cell receptor alpha variable 16" A0A0A6YYK6 14 21990496-21990938 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 39.8" "Cell type enhanced" "Detected in some" "Erythroid cells: 1.3;Gastric mucus-secreting cells: 3.1;T-cells: 5.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 48.0;T-reg: 58.0" "Lineage enriched" "Detected in single" 164 "T-cells: 58.0" "Cell line enriched" "Detected in single" 184 "JURKAT: 18.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.93e-2)" "unprognostic (1.06e-4)" "unprognostic (6.22e-3)" "unprognostic (3.67e-3)" "unprognostic (1.01e-4)" "unprognostic (1.01e-1)" "unprognostic (4.08e-2)" "unprognostic (2.79e-2)" "unprognostic (6.94e-4)" "unprognostic (5.25e-2)" "unprognostic (2.33e-1)" "unprognostic (5.27e-5)" "unprognostic (1.55e-1)" "unprognostic (3.91e-2)" "unprognostic (4.01e-1)" "unprognostic (2.07e-3)" 0.2 0.0 0.0 5.7 0.0 0.8 0.8 0.0 0.3 0.5 0.0 1.5 1.9 0.2 1.3 0.5 0.2 2.6 0.1 0.0 0.0 0.6 0.2 1.8 16.6 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 1.7 0.0 0.6 0.1 0.0 0.6 1.6 0.0 0.0 2.8 1.7 0.1 0.1 39.8 0.3 0.0 10.1 3.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 11.9 0.0 45.6 18.2 0.0 0.1 48.0 22.4 0.3 0.0 0.0 0.0 58.0 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 TRAV17 "TCRAV17S1, TCRAV3S1" ENSG00000211797 "T cell receptor alpha variable 17" A0A0B4J275 14 21997539-21998168 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 27.8" "Cell type enriched" "Detected in some" 5 "T-cells: 6.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "memory CD4 T-cell: 81.4;memory CD8 T-cell: 63.7;naive CD4 T-cell: 61.8;naive CD8 T-cell: 53.2;T-reg: 116.3" "Lineage enriched" "Detected in single" 226 "T-cells: 116.3" "Cell line enriched" "Detected in single" 221 "JURKAT: 22.0" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (8.22e-4)" "unprognostic (4.50e-3)" "unprognostic (1.37e-3)" "unprognostic (2.06e-2)" "unprognostic (2.72e-6)" "unprognostic (6.44e-2)" "unprognostic (7.45e-2)" "unprognostic (1.28e-2)" "unprognostic (1.67e-3)" "unprognostic (8.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (8.43e-3)" "unprognostic (8.53e-2)" "unprognostic (2.21e-1)" 0.2 0.0 0.0 5.9 0.0 0.5 0.2 0.0 0.2 0.5 0.0 1.2 1.8 0.3 0.8 0.6 0.6 1.4 0.1 0.0 0.0 0.2 0.4 1.4 13.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.1 1.5 0.3 0.0 3.3 2.2 0.1 0.0 27.8 0.3 0.0 10.2 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.7 0.0 3.9 0.2 81.4 63.7 0.0 0.2 61.8 53.2 0.5 0.1 0.1 0.3 116.3 22.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 TRAV2 ENSG00000211776 "T cell receptor alpha variable 2" A0A0B4J234 14 21712321-21712843 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 21 "lymphoid tissue: 56.3" "Cell type enriched" "Detected in single" 5 "T-cells: 2.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 40.9" "Lineage enriched" "Detected in single" 124 "T-cells: 40.9" "Cell line enriched" "Detected in single" 21 "Daudi: 2.1" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.38e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (1.93e-2)" "unprognostic (1.86e-3)" "unprognostic (3.64e-2)" "unprognostic (4.45e-2)" "unprognostic (2.00e-2)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (5.84e-2)" "unprognostic (9.93e-5)" "unprognostic (1.92e-1)" "unprognostic (4.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.45e-2)" 0.4 0.2 0.0 8.2 0.0 2.5 0.3 0.0 0.5 0.3 0.0 2.0 0.8 0.0 0.0 0.9 0.3 0.9 0.3 0.0 0.0 0.2 0.3 1.6 19.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.0 0.2 0.0 0.0 0.1 1.7 0.0 0.0 3.3 2.7 0.2 0.0 56.3 0.2 0.0 13.2 2.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 31.3 0.0 31.5 9.9 0.0 0.0 24.5 9.6 0.1 0.0 0.0 0.3 40.9 5.7 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 TRAV21 ENSG00000211801 "T cell receptor alpha variable 21" A0A0B4J279 14 22052514-22053056 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 63.2" "Group enriched" "Detected in some" 12 "Gastric mucus-secreting cells: 6.1;T-cells: 23.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 220.5;memory CD8 T-cell: 233.5;naive CD4 T-cell: 198.6;naive CD8 T-cell: 204.8;T-reg: 391.9" "Lineage enriched" "Detected in many" 76 "T-cells: 391.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.53e-4)" "unprognostic (1.03e-2)" "unprognostic (3.94e-3)" "unprognostic (3.69e-4)" "unprognostic (1.74e-1)" "unprognostic (1.22e-3)" "unprognostic (4.86e-3)" "unprognostic (2.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" "unprognostic (4.20e-2)" "unprognostic (9.80e-2)" "unprognostic (4.53e-3)" "unprognostic (3.13e-1)" "unprognostic (2.96e-2)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" 0.4 0.1 0.0 5.9 0.0 0.8 1.4 0.0 0.1 1.1 0.0 1.8 2.0 0.1 1.7 0.9 0.7 1.7 0.1 0.0 0.1 0.7 0.5 2.7 14.2 0.2 0.0 0.4 0.0 0.1 0.0 0.3 0.1 0.7 2.7 0.0 1.0 0.1 0.4 0.3 2.6 0.7 0.1 5.4 2.4 0.1 0.0 63.2 3.8 0.0 17.0 2.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.9 1.7 0.2 17.4 0.5 220.5 233.5 0.9 0.8 198.6 204.8 5.1 0.4 0.7 0.6 391.9 73.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.0 0.0 0.0 0.0 TRAV23DV6 "TCRAV17S1, TRAV23/DV6" ENSG00000211803 "T cell receptor alpha variable 23/delta variable 6" A0A075B6W5 14 22086407-22086961 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 26.3" "Cell type enriched" "Detected in single" 20 "T-cells: 4.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 79.3;naive CD4 T-cell: 85.6;T-reg: 65.6" "Lineage enriched" "Detected in many" 56 "T-cells: 85.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.79e-3)" "unprognostic (2.91e-2)" "unprognostic (2.01e-1)" "unprognostic (2.69e-1)" "unprognostic (2.66e-2)" "unprognostic (2.20e-2)" "unprognostic (1.19e-3)" "unprognostic (3.91e-2)" "unprognostic (1.04e-2)" "unprognostic (1.79e-1)" "unprognostic (2.24e-2)" "unprognostic (4.56e-3)" "unprognostic (1.34e-1)" "unprognostic (4.47e-2)" "unprognostic (7.44e-2)" "unprognostic (1.33e-1)" 0.5 0.1 0.0 6.4 0.0 1.1 0.5 0.0 0.0 0.5 0.0 1.2 2.1 0.2 0.0 1.0 0.5 1.3 0.3 0.0 0.0 0.1 0.5 1.8 10.3 0.0 0.1 1.3 0.0 0.1 0.0 0.0 0.0 0.6 1.8 0.0 0.5 0.1 0.1 0.1 1.0 0.5 0.0 3.3 2.2 0.0 0.0 26.3 0.6 0.0 10.8 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 2.0 0.0 3.2 0.0 79.3 19.6 0.0 0.1 85.6 21.4 1.5 0.1 0.0 0.0 65.6 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 TRAV25 "TCRAV25S1, TCRAV32S1" ENSG00000211806 "T cell receptor alpha variable 25" A0A0B4J276 14 22112347-22113031 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 15.2" "Cell type enriched" "Detected in single" 6 "T-cells: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 63 "memory CD4 T-cell: 33.5;memory CD8 T-cell: 20.9;naive CD4 T-cell: 32.6;naive CD8 T-cell: 22.5;T-reg: 49.4" "Lineage enriched" "Detected in single" 404 "T-cells: 49.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.50e-3)" "unprognostic (1.49e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-5)" "unprognostic (6.65e-3)" "unprognostic (7.53e-3)" "unprognostic (7.30e-3)" "unprognostic (1.69e-1)" "unprognostic (2.04e-1)" "unprognostic (3.52e-3)" "unprognostic (9.55e-2)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (3.74e-1)" 0.1 0.0 0.0 2.7 0.1 0.3 0.5 0.0 0.2 0.1 0.0 0.8 0.8 0.3 0.6 0.2 0.2 0.5 0.0 0.0 0.1 0.2 0.1 1.5 8.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.2 0.1 0.7 0.3 0.0 2.3 1.7 0.0 0.1 15.2 0.1 0.0 7.7 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 33.5 20.9 0.0 0.0 32.6 22.5 0.1 0.0 0.0 0.0 49.4 7.4 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 TRAV3 ENSG00000211777 "T cell receptor alpha variable 3" A0A0B4J244 14 21723713-21724321 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.1" "Cell type enriched" "Detected in some" 4 "T-cells: 6.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 48.8;memory CD8 T-cell: 33.6;naive CD4 T-cell: 51.2;naive CD8 T-cell: 47.8;T-reg: 112.7" "Lineage enriched" "Detected in single" 144 "T-cells: 112.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.32e-3)" "unprognostic (4.61e-4)" "unprognostic (2.50e-1)" "unprognostic (6.25e-3)" "unprognostic (7.75e-2)" "unprognostic (8.35e-4)" "unprognostic (8.65e-3)" "unprognostic (4.31e-3)" "unprognostic (2.88e-3)" "unprognostic (4.24e-3)" "unprognostic (5.27e-2)" "unprognostic (3.35e-1)" "unprognostic (1.91e-4)" "unprognostic (1.67e-1)" "unprognostic (6.61e-2)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" 0.2 0.2 0.0 2.9 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.5 0.1 0.2 0.6 0.5 0.0 0.0 0.1 0.2 0.8 7.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.8 0.0 0.2 0.0 0.0 0.3 1.3 0.0 0.0 2.0 1.0 0.3 0.4 10.1 0.1 0.1 5.7 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 14.3 0.0 48.8 33.6 0.1 0.1 51.2 47.8 0.7 0.1 0.0 0.0 112.7 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 6.7 0.0 0.0 0.0 TRAV4 "TCRAV20S1, TCRAV4S1" ENSG00000211778 "T cell receptor alpha variable 4" A0A0B4J268 14 21736152-21736982 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 37.9" "Cell type enriched" "Detected in some" 8 "T-cells: 8.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 66.1;memory CD4 T-cell: 81.9;memory CD8 T-cell: 124.0;naive CD4 T-cell: 77.1;naive CD8 T-cell: 81.0;T-reg: 167.9" "Lineage enriched" "Detected in many" 118 "T-cells: 167.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.13e-2)" "unprognostic (4.08e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-4)" "unprognostic (5.20e-3)" "unprognostic (1.18e-4)" "unprognostic (1.34e-2)" "unprognostic (5.48e-2)" "unprognostic (7.19e-3)" "unprognostic (2.48e-3)" "unprognostic (8.68e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-4)" "unprognostic (1.65e-1)" "unprognostic (3.23e-1)" "unprognostic (2.89e-1)" "unprognostic (6.49e-2)" 0.4 0.3 0.0 7.7 0.0 1.3 1.1 0.0 0.4 1.1 0.0 1.8 1.7 0.3 0.0 1.1 0.6 2.8 0.5 0.1 0.0 0.2 0.6 2.4 17.4 0.3 0.4 0.2 0.5 0.1 0.0 0.1 0.2 1.2 2.1 0.0 0.8 0.1 0.0 0.4 3.3 0.4 0.1 5.4 2.4 0.3 0.2 37.9 0.3 0.0 14.2 2.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.6 0.1 66.1 0.1 81.9 124.0 0.1 0.1 77.1 81.0 1.4 0.4 0.5 0.4 167.9 25.2 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.4 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 TRAV5 ENSG00000211779 "T cell receptor alpha variable 5" A0A0B4J249 14 21749178-21749705 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 12.9" "Cell type enriched" "Detected in some" 5 "T-cells: 7.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 52 "MAIT T-cell: 24.7;memory CD4 T-cell: 49.5;memory CD8 T-cell: 77.3;naive CD4 T-cell: 39.9;naive CD8 T-cell: 74.0;T-reg: 81.4" "Lineage enriched" "Detected in many" 73 "T-cells: 81.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.04e-3)" "unprognostic (2.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.69e-2)" "unprognostic (6.26e-5)" "unprognostic (3.58e-1)" "unprognostic (8.15e-2)" "unprognostic (5.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.12e-1)" "unprognostic (3.11e-2)" "unprognostic (8.38e-6)" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" "unprognostic (1.78e-1)" "unprognostic (1.70e-2)" 0.1 0.4 0.0 3.6 0.0 0.5 0.7 0.0 0.2 0.3 0.5 1.0 0.5 0.7 0.0 0.3 0.1 2.7 0.2 0.1 0.0 0.2 0.8 1.1 12.9 0.3 0.2 0.3 0.6 0.0 0.0 0.0 0.1 2.1 1.6 0.0 2.6 0.3 0.0 0.0 2.7 0.8 0.0 4.6 1.8 0.1 0.1 11.5 0.8 0.8 7.6 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.0 0.5 24.7 0.2 49.5 77.3 0.1 0.1 39.9 74.0 1.1 0.0 0.2 0.3 81.4 17.9 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 TRAV6 TCRAV5S1 ENSG00000211780 "T cell receptor alpha variable 6" A0A075B6T7 14 21768489-21769080 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 11.2" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 1.1;T-cells: 3.4" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 17.1;memory CD4 T-cell: 33.7;memory CD8 T-cell: 19.0;naive CD4 T-cell: 26.3;naive CD8 T-cell: 16.2;T-reg: 59.6" "Lineage enriched" "Detected in single" 146 "T-cells: 59.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (1.78e-1)" "unprognostic (3.49e-4)" "unprognostic (3.25e-1)" "unprognostic (2.49e-2)" "unprognostic (2.79e-1)" "unprognostic (8.90e-3)" "unprognostic (2.05e-1)" "unprognostic (1.81e-1)" "unprognostic (2.87e-5)" "unprognostic (1.32e-1)" "unprognostic (2.95e-2)" "unprognostic (3.59e-1)" "unprognostic (1.24e-2)" 0.1 0.0 0.0 2.4 0.0 0.6 0.5 0.0 0.0 0.1 0.0 1.0 0.3 0.1 0.6 0.6 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.8 5.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.2 0.2 0.0 0.0 2.3 0.0 0.0 2.7 0.8 0.1 0.4 11.2 0.1 0.0 4.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 17.1 0.2 33.7 19.0 0.0 0.1 26.3 16.2 0.4 0.0 0.0 0.0 59.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 TRAV8-1 ENSG00000211782 "T cell receptor alpha variable 8-1" A0A0A6YYK1 14 21797287-21797886 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 11.8" "Cell type enriched" "Detected in single" 9 "T-cells: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 43 "MAIT T-cell: 14.2;memory CD4 T-cell: 39.5;memory CD8 T-cell: 20.6;naive CD4 T-cell: 37.6;naive CD8 T-cell: 16.3;T-reg: 54.4" "Lineage enriched" "Detected in single" 77 "T-cells: 54.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (8.53e-3)" "unprognostic (1.98e-2)" "unprognostic (5.44e-2)" "unprognostic (1.34e-2)" "unprognostic (4.86e-4)" "unprognostic (2.84e-3)" "unprognostic (8.19e-3)" "unprognostic (1.90e-2)" "unprognostic (6.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (2.60e-1)" "unprognostic (2.31e-1)" "unprognostic (3.86e-1)" "unprognostic (5.72e-2)" 0.1 0.0 0.0 3.7 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.7 0.6 0.2 0.2 0.7 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.8 6.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.0 0.1 0.2 0.7 0.0 0.0 1.7 0.5 0.2 0.0 11.8 0.0 0.0 4.7 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 14.2 0.0 39.5 20.6 0.1 0.1 37.6 16.3 0.7 0.0 0.0 0.1 54.4 8.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 TRAV8-2 ENSG00000211786 "T cell receptor alpha variable 8-2" A0A0B4J237 14 21846537-21847221 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 24.1" "Cell type enriched" "Detected in some" 9 "T-cells: 10.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 99 "MAIT T-cell: 59.1;memory CD4 T-cell: 143.4;memory CD8 T-cell: 81.1;naive CD4 T-cell: 143.2;naive CD8 T-cell: 80.1;T-reg: 190.6" "Lineage enriched" "Detected in many" 184 "T-cells: 190.6" "Cell line enriched" "Detected in single" 6 "JURKAT: 1.9" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (5.88e-3)" "unprognostic (9.98e-4)" "unprognostic (2.31e-2)" "unprognostic (2.23e-2)" "unprognostic (9.88e-5)" "unprognostic (1.94e-3)" "unprognostic (7.22e-3)" "unprognostic (9.30e-3)" "unprognostic (2.82e-3)" "unprognostic (1.39e-1)" "unprognostic (1.69e-1)" "unprognostic (7.57e-5)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (6.66e-2)" "unprognostic (1.02e-1)" 0.3 0.1 0.0 3.2 0.0 1.9 0.2 0.0 0.0 0.2 0.0 0.7 1.1 0.2 1.6 0.5 0.2 1.4 0.1 0.0 0.0 2.7 0.2 1.2 14.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.1 0.0 0.4 0.0 0.0 0.4 1.3 0.1 0.0 4.1 1.3 0.3 0.0 24.1 0.3 0.0 6.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.0 1.1 0.1 59.1 0.2 143.4 81.1 0.3 0.3 143.2 80.1 0.7 0.2 0.2 0.1 190.6 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 0.0 0.0 TRAV8-3 ENSG00000211787 "T cell receptor alpha variable 8-3" A0A0A6YYJ7 14 21852558-21853006 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 71.1" "Cell type enriched" "Detected in single" 7 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 138.2;T-reg: 153.1" "Lineage enriched" "Detected in many" 47 "T-cells: 153.1" "Cell line enriched" "Detected in single" 6 "JURKAT: 2.9" "Low region specificity" "Detected in single" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.74e-4)" "unprognostic (5.25e-5)" "unprognostic (8.88e-4)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (9.64e-5)" "unprognostic (8.20e-2)" "unprognostic (1.25e-2)" "unprognostic (1.38e-2)" "unprognostic (6.44e-2)" "unprognostic (2.13e-2)" "unprognostic (1.46e-1)" "unprognostic (2.66e-5)" "unprognostic (2.99e-1)" "unprognostic (4.17e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-2)" 0.6 0.0 0.2 6.5 0.3 3.8 2.9 0.0 1.2 2.3 0.0 3.0 2.4 0.8 16.8 1.6 8.9 5.7 0.4 0.3 0.0 0.7 1.2 3.8 40.2 0.0 0.0 0.5 0.0 0.1 0.0 0.6 0.0 1.9 4.7 0.0 2.0 0.7 0.3 0.8 2.7 1.0 0.0 9.1 2.7 3.1 0.0 71.1 0.9 1.1 30.2 6.8 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.4 1.2 0.1 29.7 0.1 106.6 48.4 0.3 0.6 138.2 77.0 3.2 0.2 0.3 0.9 153.1 34.6 0.2 0.3 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 TRAV8-6 ENSG00000211795 "T cell receptor alpha variable 8-6" A0A0B4J262 14 21978459-21979120 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 24.7" "Group enriched" "Detected in some" 19 "Spermatocytes: 1.2;Spermatogonia: 1.5;T-cells: 3.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 89.3;memory CD8 T-cell: 64.2;naive CD4 T-cell: 92.6;naive CD8 T-cell: 38.7;T-reg: 125.0" "Lineage enriched" "Detected in many" 45 "T-cells: 125.0" "Cell line enriched" "Detected in single" 97 "JURKAT: 9.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (9.23e-4)" "unprognostic (5.47e-3)" "unprognostic (1.27e-3)" "unprognostic (7.80e-2)" "unprognostic (7.74e-5)" "unprognostic (2.88e-3)" "unprognostic (5.41e-3)" "unprognostic (2.59e-3)" "unprognostic (2.24e-2)" "unprognostic (9.25e-2)" "unprognostic (2.92e-1)" "unprognostic (9.78e-5)" "unprognostic (4.65e-1)" "unprognostic (2.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.61e-3)" 0.2 0.0 0.0 3.0 0.0 0.8 0.8 0.0 0.0 0.4 0.0 0.9 0.7 0.3 0.7 0.3 0.3 2.0 0.2 0.0 0.0 0.3 0.3 1.4 10.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.2 0.1 0.1 0.2 1.3 0.4 0.1 2.9 1.5 0.4 0.0 24.7 0.1 0.1 8.2 1.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 17.9 0.2 89.3 64.2 0.1 0.1 92.6 38.7 2.8 0.1 0.1 0.2 125.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 TRAV9-2 ENSG00000211793 "T cell receptor alpha variable 9-2" A0A087WT02 14 21941128-21941657 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 27.8" "Cell type enriched" "Detected in single" 6 "T-cells: 5.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 178.3;naive CD4 T-cell: 172.2;T-reg: 350.8" "Lineage enriched" "Detected in many" 78 "T-cells: 350.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-3)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (1.25e-4)" "unprognostic (1.14e-5)" "unprognostic (1.37e-2)" "unprognostic (2.23e-2)" "unprognostic (5.98e-4)" "unprognostic (9.53e-3)" "unprognostic (1.92e-1)" "unprognostic (2.51e-1)" "unprognostic (9.00e-4)" "unprognostic (2.49e-1)" "unprognostic (4.28e-2)" "unprognostic (3.38e-1)" "unprognostic (2.56e-2)" 0.2 0.0 0.0 5.6 0.0 0.1 0.3 0.0 0.2 0.7 0.0 1.8 0.8 0.2 0.0 0.4 0.4 1.7 0.2 0.0 0.0 0.2 1.1 1.8 18.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.4 0.0 0.1 0.4 0.2 0.2 2.0 0.5 0.0 5.0 3.1 0.1 0.0 27.8 0.2 0.2 16.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 0.8 0.0 14.3 0.6 178.3 43.4 0.2 0.3 172.2 42.5 4.4 0.3 0.2 1.1 350.8 40.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 10 "dendritic cells: 338.0;NK-cells: 580.9;T-cells: 399.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cell line enriched" "Detected in some" 5 "JURKAT: 1467.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" 9.2 5.1 1.3 140.0 1.5 53.5 9.5 1.1 2.1 7.7 1.5 18.5 26.8 6.4 5.7 12.0 7.0 26.7 5.0 1.0 1.1 5.4 11.4 31.5 322.2 2.0 1.2 6.4 2.7 0.9 2.0 2.3 1.7 9.0 19.4 0.0 19.0 4.6 1.0 9.9 49.7 4.2 1.7 92.5 27.1 2.7 1.6 1520.1 8.4 2.1 227.0 33.2 6.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 1467.5 2.0 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 296.5 2.0 0.0 1.9 0.0 45.6 7.2 4.7 869.6 3.5 693.8 17.1 1893.1 1259.3 5.8 15.7 1989.8 1450.7 37.3 359.8 8.3 9.7 3232.4 1917.5 1.3 1.5 1.1 2.1 1.0 1.1 2.0 1.2 1.7 1.7 1.6 1.9 7.3 19.2 40.8 0.0 11.7 0.0 0.3 0.0 0.0 0.0 5.9 5.5 0.0 0.0 3.1 1.8 0.0 0.2 338.0 0.0 0.0 0.5 0.6 1.1 0.7 1.5 0.0 10.7 0.0 0.0 0.1 3.2 4.6 0.8 20.2 0.0 5.3 1.5 0.3 0.0 0.0 0.1 0.0 8.4 0.0 1.9 17.4 13.9 0.0 0.0 17.3 0.0 580.9 0.0 0.0 0.0 0.1 8.2 23.6 0.3 0.0 2.4 0.7 0.0 0.0 1.1 3.5 0.0 0.1 0.5 0.0 0.1 399.0 0.1 0.1 0.4 TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 164.7;dendritic cells: 358.8;NK-cells: 264.7;T-cells: 498.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cell line enriched" "Detected in some" 45 "MOLT-4: 277.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" 18.9 3.1 0.4 3.9 0.3 1.5 8.6 0.1 1.2 11.9 0.1 21.2 1.7 8.7 0.0 14.6 15.7 2.2 4.9 0.3 0.0 9.6 12.7 32.3 8.6 0.2 0.3 18.3 3.5 0.1 4.0 0.0 0.2 14.2 2.7 0.0 7.9 0.1 3.3 6.5 115.8 0.5 0.1 190.2 16.9 8.7 0.3 109.2 16.4 1.2 10.9 14.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 3.5 0.0 0.0 0.0 0.0 277.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 35.0 8.1 47.6 47.3 0.3 7.7 46.6 40.3 2.0 10.5 0.1 0.0 76.0 42.4 0.4 0.3 0.1 1.2 0.3 0.0 0.2 0.3 0.2 0.1 0.3 0.1 8.3 9.6 52.4 0.0 164.7 0.0 0.3 0.0 1.8 0.1 6.2 9.7 4.8 5.7 3.7 1.8 0.0 0.4 358.8 1.4 0.0 2.9 1.0 1.1 0.8 4.0 0.0 16.6 0.0 1.3 0.1 10.8 8.6 0.9 20.2 0.0 15.0 1.6 0.4 0.0 0.0 0.8 0.0 9.0 0.0 4.2 63.6 18.9 0.0 0.0 19.0 15.6 264.7 0.0 0.0 20.1 0.1 70.3 30.6 0.4 0.1 2.2 2.9 0.4 65.7 4.2 12.4 0.1 0.8 1.3 0.0 0.3 498.0 1.4 0.9 0.2 TRBJ1-1 "TCRBJ1S1, TRBJ11" ENSG00000282320 "T cell receptor beta joining 1-1" A0A0J9YXA8 7 142786880-142786927 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 83.9" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 1111.5" "Lineage enriched" "Detected in all" 18 "T-cells: 1111.5" "Cell line enhanced" "Detected in some" "Daudi: 1.2;K-562: 1.2;U-266/84: 4.4;U-698: 1.0" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 58: T-cells - T-cell receptor" 2.1 0.0 0.6 33.1 0.4 7.8 0.8 0.0 0.8 1.0 0.0 4.6 5.9 1.6 0.0 2.8 0.9 4.2 0.4 0.2 0.1 0.3 6.1 5.6 44.8 0.3 0.2 1.6 3.0 0.0 0.0 0.5 0.3 1.6 7.9 0.3 1.4 0.5 3.4 0.0 6.1 0.6 0.2 18.6 9.8 0.3 0.6 83.9 0.1 5.5 48.6 2.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 1.0 0.0 0.0 0.0 46.7 1.3 2.9 163.0 0.9 240.7 5.8 622.5 480.8 1.9 1.9 690.1 869.6 16.2 62.1 1.5 4.7 1111.5 312.7 0.6 0.4 0.0 0.8 0.2 0.1 0.3 0.2 0.3 0.2 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TRBJ2-1 "TCRBJ2S1, TRBJ21" ENSG00000211764 "T cell receptor beta joining 2-1" A0A0A0MTA7 7 142796365-142796414 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 26.8;lymphoid tissue: 71.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 8.7" "Immune cell enhanced" "Detected in all" "T-reg: 1684.5" "Lineage enriched" "Detected in all" 8 "T-cells: 1684.5" "Cell line enriched" "Detected in some" 16 "MOLT-4: 2783.5" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.57e-2)" "prognostic favorable (8.15e-4)" "unprognostic (1.22e-1)" "unprognostic (1.09e-3)" "unprognostic (2.30e-5)" "unprognostic (8.63e-2)" "unprognostic (6.12e-2)" "unprognostic (3.74e-1)" "unprognostic (9.28e-2)" "unprognostic (1.07e-2)" "prognostic unfavorable (9.35e-4)" "unprognostic (2.31e-1)" "unprognostic (2.17e-2)" "unprognostic (1.11e-1)" "unprognostic (7.65e-3)" 0.7 4.2 0.8 26.9 1.0 26.8 0.4 0.0 1.4 1.0 0.0 2.1 7.8 0.4 0.0 0.0 1.4 2.2 0.7 0.3 0.0 1.0 0.6 4.5 41.7 0.0 2.2 1.6 0.0 0.0 0.0 0.7 0.2 2.8 2.9 0.8 1.2 0.0 3.1 0.0 8.4 0.7 0.1 29.8 7.5 1.2 8.7 71.3 0.8 0.0 35.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 1.9 0.0 0.9 175.1 160.3 0.0 0.0 0.0 0.0 2783.5 2.6 1.7 0.0 0.0 0.0 0.0 1.4 0.0 30.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 8.7 0.0 0.0 3.2 0.0 57.2 0.0 0.0 0.0 10.9 3.2 2.6 255.6 2.4 535.8 97.1 906.2 1179.2 2.8 69.8 916.2 888.4 11.3 209.4 4.6 8.4 1684.5 527.9 0.8 1.0 0.0 1.4 0.3 0.0 0.0 2.2 0.2 0.1 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 TRBJ2-3 "TCRBJ2S3, TRBJ23" ENSG00000211767 "T cell receptor beta joining 2-3" A0A0B4J200 7 142796847-142796895 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 86.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "thalamus: 19.7" "Group enriched" "Detected in all" 12 "gdT-cell: 1486.3;MAIT T-cell: 905.3;memory B-cell: 1210.1;memory CD4 T-cell: 1124.0;memory CD8 T-cell: 1154.0;naive B-cell: 1430.2;naive CD4 T-cell: 1106.3;naive CD8 T-cell: 1031.1;NK-cell: 933.5;T-reg: 2317.4" "Group enriched" "Detected in all" 15 "B-cells: 1430.2;NK-cells: 933.5;T-cells: 2317.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 31.8;JURKAT: 65.6;MOLT-4: 72.9;RT4: 39.1;U-698: 218.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (4.65e-3)" "unprognostic (7.01e-3)" "unprognostic (7.69e-2)" "prognostic favorable (1.47e-5)" "unprognostic (1.76e-5)" "unprognostic (1.18e-1)" "unprognostic (2.63e-1)" "unprognostic (6.84e-3)" "unprognostic (1.25e-1)" "unprognostic (3.05e-2)" "unprognostic (1.65e-1)" "unprognostic (1.81e-3)" "unprognostic (1.20e-1)" "unprognostic (1.74e-2)" "unprognostic (3.35e-1)" "unprognostic (1.64e-3)" 2.9 2.1 4.4 86.4 2.0 17.6 4.7 1.2 5.7 1.9 1.0 5.4 19.2 3.4 0.0 0.8 0.5 2.9 0.4 2.4 1.8 1.1 5.3 12.2 82.8 2.1 9.3 5.0 0.0 0.0 0.0 0.9 1.2 2.6 7.2 1.6 5.0 0.0 4.4 1.0 22.2 1.6 2.2 78.6 20.5 2.3 19.7 60.8 0.4 2.7 51.8 2.6 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 21.5 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 31.8 65.6 0.0 0.0 0.0 0.0 72.9 0.0 5.0 0.0 7.5 0.0 0.0 0.0 0.0 39.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.3 218.9 0.0 0.0 0.0 106.3 7.7 5.8 1486.3 3.1 905.3 1210.1 1124.0 1154.0 9.3 1430.2 1106.3 1031.1 43.1 933.5 10.8 18.1 2317.4 1057.6 4.4 2.0 1.2 5.7 2.4 1.8 2.1 9.3 1.2 2.2 19.7 4.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TRBJ2-5 "TCRBJ2S5, TRBJ25" ENSG00000211769 "T cell receptor beta joining 2-5" 7 142797119-142797166 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 2.7;intestine: 4.5;lymphoid tissue: 10.9;stomach 1: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 1102.2" "Lineage enriched" "Detected in all" 14 "T-cells: 1102.2" "Cell line enriched" "Detected in some" 7 "MOLT-4: 152.3" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.0 0.0 0.2 9.0 0.9 2.7 0.0 0.2 1.0 0.0 0.0 0.9 4.5 0.0 0.0 0.4 0.0 0.6 0.0 0.7 0.3 0.0 0.5 1.1 9.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 10.9 7.6 0.4 0.8 9.6 0.0 0.0 6.1 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 152.3 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 2.4 0.0 0.8 1.0 0.0 21.7 0.0 0.0 0.0 2.4 1.3 3.0 103.7 0.9 271.0 47.0 586.4 389.5 1.8 81.6 664.4 355.4 12.4 36.3 2.9 3.4 1102.2 282.2 0.2 0.9 0.2 1.0 0.7 0.3 0.5 0.2 0.4 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TRBJ2-7 "TCRBJ2S7, TRBJ27" ENSG00000211771 "T cell receptor beta joining 2-7" A0A0A0MT78 7 142797456-142797502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 45.4;lymphoid tissue: 155.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 10.8" "Group enriched" "Detected in all" 7 "MAIT T-cell: 1275.2;memory CD4 T-cell: 2387.1;memory CD8 T-cell: 2649.6;naive CD4 T-cell: 2393.9;naive CD8 T-cell: 2831.0;T-reg: 4224.6" "Lineage enriched" "Detected in all" 18 "T-cells: 4224.6" "Cell line enhanced" "Detected in some" "JURKAT: 43.8;MOLT-4: 212.6;U-698: 55.5" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.07e-3)" "unprognostic (9.26e-3)" "unprognostic (4.37e-2)" "prognostic favorable (4.79e-4)" "unprognostic (1.14e-3)" "unprognostic (2.57e-3)" "unprognostic (6.68e-3)" "unprognostic (9.60e-2)" "unprognostic (2.17e-2)" "unprognostic (6.18e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (7.27e-2)" "unprognostic (3.43e-2)" "unprognostic (1.28e-1)" "unprognostic (6.13e-3)" 3.5 4.6 1.9 96.9 3.1 45.4 2.5 1.5 4.2 0.0 0.0 7.5 18.1 5.2 0.0 0.7 0.5 9.5 0.8 0.7 2.8 0.4 0.0 4.4 108.7 1.0 2.3 2.8 5.1 0.0 0.0 1.1 0.9 2.3 6.2 0.3 3.6 0.9 0.0 0.0 36.0 0.0 0.9 54.0 25.2 2.0 10.8 155.0 0.0 0.0 47.7 4.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 8.3 43.8 0.0 0.0 0.0 3.7 212.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 0.0 0.0 0.0 42.7 6.9 10.3 360.2 6.3 1275.2 233.4 2387.1 2649.6 6.9 233.7 2393.9 2831.0 64.7 122.4 13.1 9.8 4224.6 1638.0 1.9 3.1 1.5 4.2 0.7 2.8 1.0 2.3 0.9 0.9 10.8 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 TRBV10-3 "TCRBV10S3, TCRBV12S1A1N2, TRBV103" ENSG00000275791 "T cell receptor beta variable 10-3" A0A0K0K1G6 7 142544212-142544685 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 31 "lymphoid tissue: 88.6" "Group enriched" "Detected in some" 5 "Late spermatids: 1.7;T-cells: 5.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 160.1;T-reg: 203.1" "Lineage enriched" "Detected in single" 375 "T-cells: 203.1" "Cell line enriched" "Detected in single" 53 "MOLT-4: 49.7" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.61e-3)" "unprognostic (4.86e-3)" "unprognostic (2.44e-2)" "unprognostic (8.96e-3)" "unprognostic (3.16e-1)" "unprognostic (4.23e-6)" "unprognostic (9.84e-4)" "unprognostic (7.96e-2)" "unprognostic (4.05e-2)" "unprognostic (7.99e-4)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (9.59e-6)" "unprognostic (5.93e-2)" "unprognostic (1.69e-1)" "unprognostic (1.05e-1)" "unprognostic (1.80e-3)" 0.3 0.2 0.0 8.0 0.0 2.8 0.2 0.0 0.0 0.4 0.0 1.1 0.0 0.1 0.0 0.3 0.2 1.0 0.1 0.0 0.0 0.1 0.4 0.5 16.8 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.5 0.8 0.0 0.9 0.1 0.0 0.0 1.4 0.3 0.0 2.1 2.3 0.1 0.1 88.6 0.2 0.0 12.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.9 0.0 49.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 9.3 0.4 77.0 160.1 0.0 0.3 101.7 41.2 0.3 0.1 0.5 0.5 203.1 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 TRBV12-4 "TCRBV12S4, TCRBV8S2A1T, TRBV124" ENSG00000276953 "T cell receptor beta variable 12-4" A0A0B4J2E0 7 142563740-142564245 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 44 "lymphoid tissue: 110.3" "Cell type enriched" "Detected in some" 5 "T-cells: 5.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 32 "memory CD4 T-cell: 28.6;memory CD8 T-cell: 38.8;naive CD4 T-cell: 39.7;naive CD8 T-cell: 33.7;T-reg: 54.4" "Lineage enriched" "Detected in single" 68 "T-cells: 54.4" "Cell line enriched" "Detected in some" 11 "LHCN-M2: 51.6" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.97e-4)" "unprognostic (1.20e-4)" "unprognostic (7.96e-2)" "unprognostic (1.32e-3)" "unprognostic (3.96e-4)" "unprognostic (1.20e-2)" "unprognostic (5.27e-3)" "unprognostic (1.50e-2)" "unprognostic (9.59e-4)" "unprognostic (1.53e-2)" "unprognostic (1.25e-1)" "unprognostic (8.22e-5)" "unprognostic (4.32e-2)" "unprognostic (5.32e-3)" "unprognostic (1.44e-1)" "unprognostic (5.08e-3)" 0.5 0.0 0.0 6.2 0.0 1.3 0.6 0.0 0.2 0.4 0.0 1.2 0.3 0.4 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 1.2 1.1 21.5 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.2 0.2 0.1 0.3 2.4 0.1 0.0 2.7 2.3 0.6 0.0 110.3 0.3 0.2 2.3 1.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.7 0.0 4.2 1.9 0.4 1.9 0.2 0.0 0.2 51.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 28.6 38.8 0.0 0.0 39.7 33.7 0.7 0.0 0.0 0.2 54.4 10.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 TRBV15 "TCRBV15S1, TCRBV24S1A3T" ENSG00000276819 "T cell receptor beta variable 15" 7 142592928-142593473 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 67 "lymphoid tissue: 46.9" "Cell type enriched" "Detected in single" 27 "T-cells: 2.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 48 "MAIT T-cell: 21.9;memory CD4 T-cell: 14.6;memory CD8 T-cell: 21.1;naive CD4 T-cell: 18.8;naive CD8 T-cell: 12.3;T-reg: 27.8" "Lineage enriched" "Detected in single" 158 "T-cells: 27.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.07e-2)" "unprognostic (1.03e-3)" "unprognostic (1.89e-3)" "unprognostic (1.39e-3)" "unprognostic (2.09e-4)" "unprognostic (1.08e-2)" "unprognostic (6.75e-2)" "unprognostic (5.47e-3)" "unprognostic (7.77e-2)" "unprognostic (4.14e-2)" "unprognostic (3.86e-1)" "unprognostic (2.52e-3)" "unprognostic (2.38e-1)" "unprognostic (8.34e-2)" "unprognostic (3.23e-1)" "unprognostic (2.55e-2)" 0.1 0.1 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.4 0.1 0.0 46.9 0.1 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 21.9 0.0 14.6 21.1 0.0 0.0 18.8 12.3 0.1 0.0 0.0 0.0 27.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 TRBV18 TCRBV18S1 ENSG00000276557 "T cell receptor beta variable 18" A0A087X0M5 7 142615716-142616415 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 17 "lymphoid tissue: 27.5" "Cell type enriched" "Detected in single" 13 "T-cells: 6.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 102.0" "Lineage enriched" "Detected in single" 316 "T-cells: 102.0" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.55e-2)" "unprognostic (1.14e-3)" "unprognostic (4.53e-3)" "unprognostic (7.74e-4)" "unprognostic (2.60e-2)" "unprognostic (1.08e-4)" "unprognostic (3.11e-1)" "unprognostic (6.76e-3)" "unprognostic (3.67e-2)" "unprognostic (7.81e-4)" "unprognostic (1.41e-1)" "unprognostic (1.72e-1)" "unprognostic (3.28e-6)" "unprognostic (3.80e-1)" "unprognostic (4.42e-2)" "unprognostic (4.02e-2)" "unprognostic (2.47e-2)" 0.2 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.1 0.8 8.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.0 0.1 0.0 0.0 0.3 1.6 0.2 0.0 1.7 0.5 0.0 0.0 27.5 0.2 0.0 2.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 3.0 0.2 46.6 10.8 0.0 0.0 49.3 16.9 0.2 0.1 0.1 0.0 102.0 14.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 TRBV19 "TCRBV17S1A1T, TCRBV19S1" ENSG00000211746 "T cell receptor beta variable 19" A0A075B6N1 7 142618849-142619532 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 53.4" "Cell type enriched" "Detected in some" 5 "T-cells: 11.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 50.8;memory CD8 T-cell: 40.2;naive CD4 T-cell: 71.1;naive CD8 T-cell: 53.5;T-reg: 88.5" "Lineage enriched" "Detected in single" 191 "T-cells: 88.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.62e-3)" "unprognostic (8.91e-4)" "unprognostic (1.14e-2)" "unprognostic (5.81e-3)" "unprognostic (2.38e-2)" "unprognostic (2.29e-4)" "unprognostic (3.96e-3)" "unprognostic (3.62e-3)" "unprognostic (4.51e-3)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (9.78e-2)" "unprognostic (4.14e-2)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" 0.6 0.1 0.0 5.7 0.0 0.7 0.7 0.1 0.3 0.8 0.0 1.2 0.5 0.5 0.0 0.4 0.3 3.7 0.1 0.1 0.0 0.2 0.7 1.1 28.5 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.1 0.4 2.1 0.0 0.2 0.3 0.1 0.4 3.0 0.2 0.0 3.8 2.9 0.1 0.1 53.4 0.5 0.2 1.9 0.5 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 1.4 0.1 13.5 0.4 50.8 40.2 0.1 0.0 71.1 53.5 0.4 0.1 0.2 0.0 88.5 15.5 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 TRBV2 "TCRBV22S1A2N1T, TCRBV2S1" ENSG00000226660 "T cell receptor beta variable 2" A0A1B0GX68 7 142300924-142301432 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "lymphoid tissue: 89.2" "Cell type enriched" "Detected in single" 80 "T-cells: 8.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 120.3;memory CD8 T-cell: 64.5;naive CD4 T-cell: 71.5;naive CD8 T-cell: 44.5;T-reg: 122.7" "Lineage enriched" "Detected in many" 21 "T-cells: 122.7" "Cell line enriched" "Detected in single" 10 "RPMI-8226: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.62e-4)" "unprognostic (4.94e-4)" "unprognostic (5.79e-2)" "unprognostic (1.29e-3)" "unprognostic (1.09e-1)" "unprognostic (4.71e-5)" "unprognostic (3.60e-2)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (1.16e-2)" "unprognostic (1.94e-2)" "unprognostic (1.77e-1)" "unprognostic (3.70e-5)" "unprognostic (3.83e-1)" "unprognostic (6.31e-2)" "unprognostic (1.89e-1)" "unprognostic (3.41e-2)" 1.1 0.3 0.0 8.3 0.0 3.9 1.2 0.0 0.1 1.1 0.0 2.6 2.5 0.3 1.1 1.7 0.2 2.4 0.1 0.0 0.0 0.4 0.9 1.6 25.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.8 2.1 0.0 0.3 0.5 0.0 0.3 1.7 0.8 0.0 6.8 3.5 0.3 0.0 89.2 0.5 0.3 22.1 3.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.9 0.0 5.5 0.1 120.3 64.5 0.3 0.1 71.5 44.5 1.2 0.1 0.1 5.8 122.7 29.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 TRBV20-1 "TCRBV20S1, TCRBV2S1, TRBV201" ENSG00000211747 "T cell receptor beta variable 20-1" A0A075B6N2 7 142626649-142627399 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 161.4" "Cell type enriched" "Detected in some" 15 "T-cells: 26.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 351.7" "Lineage enriched" "Detected in many" 115 "T-cells: 351.7" "Group enriched" "Detected in some" 8 "Karpas-707: 2.4;MOLT-4: 5.0;REH: 2.5;RH-30: 3.0" "Not detected" "Not detected" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.25e-3)" "prognostic favorable (4.40e-5)" "unprognostic (1.39e-2)" "prognostic favorable (8.49e-4)" "unprognostic (8.83e-2)" "unprognostic (2.69e-3)" "unprognostic (4.34e-2)" "unprognostic (8.75e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.30e-2)" "unprognostic (8.86e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (1.11e-5)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (3.41e-2)" 1.7 0.2 0.1 13.6 0.1 5.1 0.6 0.1 0.2 0.6 0.0 2.4 0.5 0.3 0.0 0.7 0.7 3.2 0.2 0.1 0.0 0.5 0.6 2.7 53.3 0.2 0.0 0.5 0.2 0.0 0.8 0.0 0.3 0.9 3.1 0.0 0.5 0.2 0.1 1.9 6.0 0.9 0.1 7.3 3.6 0.3 0.1 161.4 1.0 0.0 6.0 2.2 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 5.0 0.2 0.0 0.0 0.0 2.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.6 0.2 4.6 0.3 231.9 1.1 192.7 76.4 0.6 0.6 144.0 58.9 2.3 0.3 0.8 0.4 351.7 50.2 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 TRBV23-1 "TCRBV19S1P, TCRBV23S1, TRBV231" ENSG00000211749 "T cell receptor beta variable 23-1 (non-functional)" 7 142645961-142646467 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-5)" "unprognostic (7.32e-4)" "unprognostic (1.71e-4)" "unprognostic (1.34e-3)" "unprognostic (6.71e-3)" "unprognostic (1.28e-3)" "unprognostic (4.64e-2)" "unprognostic (1.17e-6)" "unprognostic (1.14e-1)" "unprognostic (5.86e-3)" "unprognostic (1.37e-1)" 0.3 0.0 0.0 3.4 0.1 2.2 0.1 0.1 0.1 0.2 0.0 0.4 0.3 0.1 0.6 0.1 0.2 1.0 0.3 0.0 0.0 0.2 0.2 0.7 8.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.4 0.0 0.2 0.1 2.0 0.1 0.0 2.2 0.2 0.0 0.0 11.7 0.3 0.1 5.9 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.9 0.5 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.1 1.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 TRBV24-1 "TCRBV15S1, TCRBV24S1, TRBV241" ENSG00000211750 "T cell receptor beta variable 24-1" A0A075B6N3 7 142656701-142657213 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.7;lymphoid tissue: 6.7" "Cell type enriched" "Detected in single" 23 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "basal ganglia: 2.7" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 26.6" "Lineage enriched" "Detected in single" 129 "T-cells: 26.6" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (1.64e-5)" "unprognostic (1.59e-1)" "unprognostic (9.71e-3)" "unprognostic (3.82e-1)" "unprognostic (9.30e-2)" "unprognostic (3.08e-2)" "unprognostic (1.81e-1)" "unprognostic (6.73e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-7)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.76e-3)" "unprognostic (4.39e-2)" 0.2 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.5 0.3 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.4 2.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 1.0 0.0 0.9 0.2 0.0 1.3 1.6 0.4 0.5 6.7 0.1 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 9.0 0.0 5.7 0.0 15.4 15.5 0.0 0.0 11.4 26.6 0.2 0.0 0.0 0.0 23.2 4.6 0.1 2.7 0.0 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 TRBV25-1 "TCRBV11S1A1T, TCRBV25S1, TRBV251" ENSG00000282499 "T cell receptor beta variable 25-1" A0A075B6N4 7 142670740-142671244 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 24.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.5;T-cells: 2.7" "Group enriched" "Detected in some" 9 "basal ganglia: 4.4;cerebral cortex: 2.3" "Group enriched" "Detected in many" 51 "MAIT T-cell: 8.3;memory CD4 T-cell: 8.7;memory CD8 T-cell: 13.3;naive CD4 T-cell: 12.4;naive CD8 T-cell: 12.1;T-reg: 25.8" "Lineage enriched" "Detected in single" 106 "T-cells: 25.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.1 0.8 0.2 1.7 4.4 0.5 0.0 0.0 2.3 0.0 0.0 0.1 0.4 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.3 3.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 3.0 0.0 0.8 0.1 0.0 1.0 0.2 0.7 0.2 24.8 0.1 0.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.3 0.0 8.7 13.3 0.2 0.0 12.4 12.1 0.2 0.0 0.0 0.0 25.8 2.9 0.2 4.4 0.0 2.3 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 TRBV27 "TCRBV14S1, TCRBV27S1" ENSG00000211752 "T cell receptor beta variable 27" A0A0K0K1C4 7 142715346-142715861 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 81.6" "Cell type enriched" "Detected in some" 4 "T-cells: 6.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 61.1;memory CD8 T-cell: 112.2;naive CD4 T-cell: 48.2;naive CD8 T-cell: 75.8;T-reg: 94.7" "Lineage enriched" "Detected in single" 137 "T-cells: 112.2" "Group enriched" "Detected in some" 4 "HAP1: 2.9;JURKAT: 3.3;U-937: 3.6" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.08e-2)" "unprognostic (2.10e-2)" "unprognostic (5.66e-2)" "unprognostic (5.85e-4)" "unprognostic (8.84e-2)" "unprognostic (7.89e-2)" "unprognostic (1.91e-2)" "unprognostic (1.28e-4)" "unprognostic (1.49e-1)" "unprognostic (4.36e-2)" "unprognostic (1.91e-7)" "unprognostic (4.03e-1)" "unprognostic (3.91e-2)" "unprognostic (8.10e-2)" "unprognostic (6.43e-2)" 0.6 0.5 0.0 3.5 0.6 1.9 0.8 0.0 0.3 0.7 0.0 1.2 1.0 0.9 0.1 0.8 0.2 1.8 0.2 0.0 0.0 0.4 0.5 1.7 19.7 0.0 0.3 0.5 0.2 0.0 0.1 0.1 0.0 0.5 1.7 0.0 1.7 0.0 0.3 0.2 2.8 0.2 0.0 4.8 1.9 5.7 0.2 81.6 0.6 0.8 10.6 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.4 0.1 0.6 3.3 0.0 10.4 0.1 61.1 112.2 0.1 0.1 48.2 75.8 0.8 0.1 0.2 0.1 94.7 27.3 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 TRBV28 "TCRBV28S1, TCRBV3S1" ENSG00000211753 "T cell receptor beta variable 28" A0A5B6 7 142720660-142721160 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "lymphoid tissue: 199.4" "Cell type enriched" "Detected in some" 12 "T-cells: 33.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 154.5" "Lineage enriched" "Detected in many" 79 "T-cells: 154.5" "Cell line enriched" "Detected in single" 30 "JURKAT: 23.7" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.34e-3)" "prognostic favorable (1.52e-4)" "unprognostic (1.94e-3)" "prognostic favorable (2.48e-5)" "unprognostic (5.54e-2)" "prognostic favorable (3.62e-4)" "unprognostic (5.76e-2)" "unprognostic (2.33e-3)" "prognostic favorable (1.35e-5)" "unprognostic (2.47e-3)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.48e-8)" "unprognostic (1.27e-1)" "unprognostic (9.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.94e-3)" 0.5 0.9 0.0 9.3 0.2 3.0 2.1 0.2 0.2 1.2 0.0 2.6 3.4 0.6 0.3 1.3 0.3 2.9 0.5 0.0 0.0 0.5 1.9 3.5 24.8 0.0 0.0 0.5 0.2 0.0 0.1 0.1 0.0 0.7 1.7 0.0 1.3 0.3 0.2 0.1 4.0 0.3 0.0 9.5 2.0 0.4 0.0 199.4 0.5 0.6 33.8 5.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 3.8 0.0 26.1 0.5 94.5 80.1 0.1 0.2 98.1 53.3 1.9 1.6 0.1 0.4 154.5 34.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 0.0 0.6 0.0 TRBV29-1 "TCRBV29S1, TCRBV4S1A1T, TRBV291" ENSG00000232869 "T cell receptor beta variable 29-1" A0A5B7 7 142740206-142740894 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 98.5" "Cell type enriched" "Detected in single" 11 "T-cells: 4.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "MAIT T-cell: 45.1;memory CD4 T-cell: 128.6;memory CD8 T-cell: 83.2;naive CD4 T-cell: 137.8;naive CD8 T-cell: 110.8;T-reg: 178.2" "Lineage enriched" "Detected in many" 69 "T-cells: 178.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "prognostic favorable (1.23e-4)" "unprognostic (9.31e-4)" "unprognostic (1.29e-1)" "unprognostic (8.13e-3)" "unprognostic (3.28e-2)" "unprognostic (3.47e-4)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (9.15e-2)" "unprognostic (3.93e-2)" "unprognostic (1.94e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.45e-1)" "unprognostic (2.46e-2)" "unprognostic (2.29e-1)" "unprognostic (2.05e-1)" 0.8 0.3 0.0 6.5 0.0 4.4 1.2 0.3 0.1 1.4 0.1 1.9 2.7 0.6 0.0 1.0 0.3 2.6 0.2 0.0 0.0 0.4 1.2 1.5 21.7 0.0 0.0 0.6 21.2 0.0 0.1 0.0 0.0 0.7 2.0 0.0 0.7 0.6 0.1 0.4 3.9 1.2 0.0 5.4 2.3 0.1 0.0 98.5 0.6 0.5 23.4 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.1 0.7 0.1 45.1 2.0 128.6 83.2 0.1 1.8 137.8 110.8 2.5 0.2 0.3 0.7 178.2 51.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 TRBV3-1 "TCRBV3S1, TCRBV9S1A1T, TRBV31" ENSG00000237702 "T cell receptor beta variable 3-1" A0A576 7 142308542-142309048 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 22 "lymphoid tissue: 51.1" "Group enriched" "Detected in some" 22 "Plasma cells: 10.1;T-cells: 12.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 52.4;memory CD8 T-cell: 45.9;naive CD4 T-cell: 71.6;naive CD8 T-cell: 117.4;T-reg: 99.6" "Lineage enriched" "Detected in many" 32 "T-cells: 117.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.98e-5)" "unprognostic (2.38e-3)" "unprognostic (5.19e-3)" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (6.19e-4)" "unprognostic (1.46e-2)" "unprognostic (5.42e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.56e-1)" "unprognostic (2.20e-1)" "unprognostic (2.01e-4)" "unprognostic (1.75e-1)" "unprognostic (1.13e-3)" "unprognostic (1.53e-2)" "unprognostic (1.26e-2)" 0.4 0.0 0.0 5.3 0.0 1.9 0.4 0.0 0.1 0.3 0.0 0.9 0.5 0.3 0.1 0.3 0.3 1.2 0.2 0.0 0.0 0.1 0.2 0.8 10.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 1.0 0.0 0.8 0.2 0.0 0.2 2.2 0.2 0.0 2.7 1.0 0.0 0.0 51.1 0.3 0.1 10.4 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.1 0.3 1.8 0.1 16.6 0.2 52.4 45.9 0.1 0.1 71.6 117.4 2.0 0.4 0.1 0.4 99.6 29.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 TRBV4-1 "BV07S1J2.7, TCRBV4S1, TCRBV7S1A1N2T, TRBV41" ENSG00000211710 "T cell receptor beta variable 4-1" A0A577 7 142313184-142313666 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 115.0" "Cell type enriched" "Detected in some" 7 "T-cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 176.7" "Lineage enriched" "Detected in many" 89 "T-cells: 176.7" "Cell line enriched" "Detected in single" 8 "U-266/84: 1.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.58e-4)" "unprognostic (3.14e-3)" "unprognostic (1.49e-2)" "unprognostic (5.74e-4)" "unprognostic (1.88e-1)" "unprognostic (6.43e-3)" "unprognostic (5.89e-2)" "unprognostic (2.96e-2)" "unprognostic (6.43e-3)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (2.79e-2)" "unprognostic (6.71e-5)" "unprognostic (1.76e-1)" "unprognostic (3.56e-2)" "unprognostic (1.67e-2)" "unprognostic (8.99e-2)" 0.5 0.0 0.0 7.1 0.1 2.6 0.7 0.0 0.2 0.8 0.0 0.8 0.1 0.2 0.7 1.1 0.9 0.8 0.1 0.0 0.0 0.4 0.4 0.7 15.3 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.5 0.8 0.0 0.2 0.0 0.1 0.2 4.3 0.4 0.1 4.1 2.3 0.1 0.0 115.0 0.3 0.0 10.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.0 0.2 0.1 2.5 0.1 40.2 0.1 69.8 167.3 0.0 0.2 152.1 152.7 1.9 0.8 0.4 0.8 176.7 43.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 TRBV4-2 "TCRBV4S2, TCRBV7S3A2T, TRBV42" ENSG00000211745 "T cell receptor beta variable 4-2" A0A539 7 142345421-142345985 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 21.0" "Cell type enriched" "Detected in some" 8 "T-cells: 23.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 100.2" "Lineage enriched" "Detected in single" 293 "T-cells: 100.2" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.89e-3)" "unprognostic (4.65e-4)" "unprognostic (1.28e-3)" "unprognostic (1.06e-2)" "unprognostic (4.60e-2)" "unprognostic (7.05e-4)" "unprognostic (2.11e-1)" "unprognostic (1.67e-2)" "unprognostic (1.19e-3)" "unprognostic (1.32e-2)" "unprognostic (6.75e-2)" "unprognostic (3.42e-1)" "unprognostic (2.82e-4)" "unprognostic (5.50e-2)" "unprognostic (5.99e-2)" "unprognostic (2.16e-1)" "unprognostic (1.48e-2)" 0.2 0.0 0.0 1.4 0.0 0.6 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.3 0.2 0.4 5.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 1.5 0.1 0.0 2.3 0.3 0.5 0.0 21.0 0.3 0.0 4.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 100.2 0.0 25.6 27.8 0.1 0.0 23.9 14.4 0.1 0.0 0.2 0.3 44.8 8.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 23.9 0.0 0.0 0.0 TRBV5-1 "TCRBV5S1, TCRBV5S1A1T, TRBV51" ENSG00000211734 "T cell receptor beta variable 5-1" A0A578 7 142320677-142321544 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 44.0" "Cell type enriched" "Detected in some" 11 "T-cells: 13.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 211.6;T-reg: 295.5" "Lineage enriched" "Detected in many" 111 "T-cells: 295.5" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.26e-4)" "unprognostic (1.36e-3)" "unprognostic (2.59e-2)" "unprognostic (1.49e-3)" "unprognostic (6.65e-2)" "unprognostic (7.02e-5)" "unprognostic (2.55e-2)" "unprognostic (3.66e-2)" "unprognostic (4.29e-3)" "unprognostic (5.85e-4)" "unprognostic (3.55e-2)" "unprognostic (4.36e-1)" "unprognostic (5.96e-7)" "unprognostic (2.63e-1)" "unprognostic (2.52e-2)" "unprognostic (4.06e-2)" "unprognostic (2.97e-2)" 0.3 0.0 0.0 4.8 0.0 1.1 0.2 0.0 0.0 0.4 0.0 0.7 1.0 0.1 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.2 0.7 9.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.3 1.9 0.1 0.0 2.6 1.6 0.2 0.0 44.0 0.2 0.0 8.9 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 2.6 0.2 11.0 0.4 166.1 65.4 0.4 0.4 211.6 128.7 2.6 0.5 0.5 0.3 295.5 82.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 TRBV5-4 "TCRBV5S4, TCRBV5S6A3N2T, TRBV54" ENSG00000230099 "T cell receptor beta variable 5-4" A0A0C4DH59 7 142462916-142463581 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "lymphoid tissue: 22.1;pancreas: 11.6" "Group enriched" "Detected in some" 9 "Plasma cells: 6.1;T-cells: 6.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 115.7" "Lineage enriched" "Detected in many" 115 "T-cells: 115.7" "Cell line enriched" "Detected in some" 5 "MOLT-4: 11.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.48e-3)" "unprognostic (6.75e-4)" "unprognostic (1.60e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-1)" "unprognostic (1.76e-3)" "unprognostic (5.82e-2)" "unprognostic (2.79e-2)" "unprognostic (1.59e-2)" "unprognostic (4.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.60e-4)" "unprognostic (2.77e-1)" "unprognostic (4.95e-2)" "unprognostic (4.78e-3)" "unprognostic (1.64e-2)" 0.2 0.1 0.0 2.4 0.2 1.2 0.1 0.0 0.0 0.2 0.0 0.7 0.8 0.0 0.1 0.3 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.4 8.2 0.2 0.0 0.0 11.6 0.0 0.0 0.0 0.2 0.2 1.0 0.7 0.5 0.0 0.2 0.3 1.1 0.0 0.0 2.2 1.0 0.2 0.0 22.1 0.2 0.0 8.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 2.3 0.0 0.0 0.5 0.0 0.2 0.2 0.0 1.3 0.1 2.1 0.0 49.7 26.7 0.0 0.1 62.8 36.4 1.0 0.1 0.1 0.1 115.7 18.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 TRBV5-6 "TCRBV5S2, TCRBV5S6, TRBV56" ENSG00000211728 "T cell receptor beta variable 5-6" A0A599 7 142500028-142500534 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "lymphoid tissue: 33.8" "Group enriched" "Detected in some" 21 "Early spermatids: 13.5;Late spermatids: 14.6;T-cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 40.2;memory CD8 T-cell: 22.9;naive CD4 T-cell: 35.9;naive CD8 T-cell: 45.2;T-reg: 66.0" "Lineage enriched" "Detected in many" 56 "T-cells: 66.0" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.27e-3)" "unprognostic (8.46e-3)" "unprognostic (1.20e-1)" "unprognostic (7.21e-2)" "unprognostic (5.25e-1)" "unprognostic (3.45e-4)" "unprognostic (5.72e-2)" "unprognostic (6.24e-2)" "unprognostic (1.57e-2)" "unprognostic (1.46e-3)" "unprognostic (2.64e-2)" "unprognostic (2.39e-1)" "unprognostic (2.26e-7)" "unprognostic (7.62e-2)" "unprognostic (3.14e-2)" "unprognostic (2.41e-1)" "unprognostic (1.34e-1)" 0.2 0.0 0.0 2.1 0.0 0.7 0.3 0.0 0.1 0.5 0.0 0.6 0.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.1 0.1 0.8 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.2 1.1 0.1 0.0 1.9 0.4 1.7 0.0 33.8 0.1 0.1 5.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.9 0.0 3.0 0.1 40.2 22.9 0.1 0.1 35.9 45.2 1.1 0.0 0.1 0.2 66.0 17.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 TRBV6-2 "TCRBV13S2A1T, TCRBV6S2, TRBV62" ENSG00000283063 "T cell receptor beta variable 6-2" "A0A0J9YXY3, P0DPF7" 7 142349152-142349664 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 8.2" "Cell type enriched" "Detected in single" 10 "T-cells: 6.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 92.1" "Lineage enriched" "Detected in single" 175 "T-cells: 92.1" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.2 0.0 0.0 2.4 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.5 8.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 2.3 0.2 0.0 0.0 4.6 0.3 0.0 5.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 92.1 0.2 24.0 26.4 0.0 0.0 21.7 17.5 0.5 0.0 0.1 0.1 40.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 TRBV6-5 "TCRBV13S1, TCRBV6S5, TRBV65" ENSG00000211721 "T cell receptor beta variable 6-5" A0A0K0K1A5 7 142450947-142451448 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 82.3" "Cell type enriched" "Detected in single" 121 "T-cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 133.8;T-reg: 137.9" "Lineage enriched" "Detected in many" 54 "T-cells: 137.9" "Cell line enriched" "Detected in some" 8 "HL-60: 61.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.42e-3)" "unprognostic (7.43e-4)" "unprognostic (1.11e-2)" "unprognostic (2.20e-3)" "unprognostic (1.38e-1)" "unprognostic (8.63e-5)" "unprognostic (1.55e-2)" "unprognostic (1.51e-3)" "unprognostic (8.72e-3)" "unprognostic (2.11e-3)" "unprognostic (7.03e-2)" "unprognostic (4.82e-1)" "prognostic unfavorable (5.40e-5)" "unprognostic (3.12e-2)" "unprognostic (4.17e-2)" "unprognostic (7.43e-3)" "unprognostic (3.06e-2)" 0.4 0.2 0.0 4.1 0.0 2.3 0.5 0.0 0.1 0.4 0.0 0.9 1.0 0.2 0.0 0.2 0.3 1.6 0.1 0.0 0.0 0.1 0.3 2.4 16.1 0.0 0.0 0.3 7.3 0.0 0.0 0.1 0.0 0.3 1.2 0.2 0.4 0.1 0.0 0.3 2.0 0.3 0.0 3.4 1.6 0.1 0.0 82.3 0.4 0.7 12.0 1.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.5 0.2 0.2 1.0 0.1 32.8 0.3 78.7 76.2 0.1 0.4 92.0 133.8 2.5 0.2 0.4 0.4 137.9 59.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.1 TRBV6-6 "TCRBV13S6A2T, TCRBV6S6, TRBV66" ENSG00000211724 "T cell receptor beta variable 6-6" A0A0A6YYG2 7 142469537-142470013 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 14.7" "Cell type enriched" "Detected in single" 37 "T-cells: 3.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 81.4" "Lineage enriched" "Detected in single" 98 "T-cells: 81.4" "Cell line enriched" "Detected in some" 10 "HL-60: 10.4" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.69e-4)" "unprognostic (3.82e-4)" "unprognostic (3.66e-2)" "unprognostic (2.55e-2)" "unprognostic (8.55e-2)" "unprognostic (9.93e-5)" "unprognostic (4.36e-1)" "unprognostic (1.94e-2)" "unprognostic (1.09e-2)" "unprognostic (3.42e-2)" "unprognostic (5.90e-2)" "unprognostic (2.27e-1)" "unprognostic (1.78e-3)" "unprognostic (2.40e-1)" "unprognostic (2.22e-2)" "unprognostic (4.18e-2)" "unprognostic (2.01e-2)" 0.2 0.0 0.0 2.7 0.1 0.8 0.5 0.0 0.1 0.1 0.0 0.8 0.8 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.2 0.0 0.9 5.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.7 0.1 1.6 0.0 0.0 0.1 1.2 0.1 0.0 2.9 0.8 0.0 0.0 14.7 0.2 0.0 10.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.5 0.3 14.7 0.0 34.6 47.9 0.0 0.1 48.9 21.3 0.8 0.1 0.2 0.2 81.4 12.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 TRBV7-2 "TCRBV6S5A1N1, TCRBV7S2, TRBV72" ENSG00000282939 "T cell receptor beta variable 7-2" A0A1B0GXF2 7 142352819-142353358 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 35.6;lymphoid tissue: 85.5" "Cell type enriched" "Detected in some" 5 "T-cells: 33.0" "Region enriched" "Detected in single" 5 "hypothalamus: 1.1" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 397.4;T-reg: 570.3" "Lineage enriched" "Detected in many" 79 "T-cells: 570.3" "Group enriched" "Detected in some" 9 "JURKAT: 55.7;MOLT-4: 93.6;U-937: 49.0" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.9 0.1 0.0 15.0 0.1 0.0 2.2 0.0 0.2 2.2 0.0 1.2 1.7 0.0 35.6 0.6 0.5 0.0 0.2 0.0 1.1 0.5 0.3 5.5 49.0 0.0 0.0 0.1 0.2 0.0 1.0 0.1 0.0 0.3 4.6 0.0 0.4 0.4 0.0 0.2 4.7 1.1 0.0 5.8 4.7 0.0 0.2 85.5 0.7 0.0 43.0 2.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.7 0.0 0.0 0.0 0.0 93.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.0 0.0 49.0 0.0 1.1 2.3 0.7 11.9 1.2 55.5 0.7 397.4 178.6 2.7 0.7 302.2 110.6 1.2 0.5 1.9 7.2 570.3 104.9 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.0 0.2 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 TRBV7-6 "TCRBV6S3A1N1T, TCRBV7S6, TRBV76" ENSG00000211727 "T cell receptor beta variable 7-6" A0A1B0GX31 7 142492132-142492673 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 35.3" "Group enriched" "Detected in some" 15 "Gastric mucus-secreting cells: 5.1;T-cells: 7.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 22 "memory CD4 T-cell: 54.7;memory CD8 T-cell: 42.7;naive CD4 T-cell: 62.0;naive CD8 T-cell: 37.2;T-reg: 86.1" "Lineage enriched" "Detected in many" 52 "T-cells: 86.1" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (4.74e-2)" "unprognostic (1.21e-2)" "unprognostic (1.37e-2)" "unprognostic (4.25e-5)" "unprognostic (4.86e-3)" "unprognostic (4.06e-5)" "unprognostic (7.74e-2)" "unprognostic (3.83e-5)" "unprognostic (6.50e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (9.86e-5)" "unprognostic (1.83e-1)" "unprognostic (7.27e-2)" "unprognostic (5.90e-2)" "unprognostic (6.22e-3)" 0.1 0.0 0.5 3.7 0.3 1.3 0.2 0.2 0.4 0.1 0.1 0.6 0.0 0.1 5.3 1.7 0.1 1.4 0.0 0.5 0.2 0.1 0.4 0.8 6.9 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.0 0.4 0.3 0.0 0.3 1.1 0.0 0.4 3.7 1.1 0.5 1.0 35.3 0.2 0.0 7.6 2.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 2.5 0.1 54.7 42.7 0.1 0.3 62.0 37.2 1.6 0.1 0.1 0.1 86.1 17.1 0.5 0.3 0.2 0.4 0.5 0.2 0.5 0.3 0.3 0.4 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 TRBV7-9 "TCRBV6S4A1, TCRBV7S9, TRBV79" ENSG00000278030 "T cell receptor beta variable 7-9" P04435 7 142529290-142529762 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 55.4" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 9.2;Late spermatids: 5.4;T-cells: 22.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 37 "memory CD4 T-cell: 48.4;memory CD8 T-cell: 81.7;naive CD4 T-cell: 67.3;naive CD8 T-cell: 73.5;T-reg: 95.1" "Lineage enriched" "Detected in many" 87 "T-cells: 95.1" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 4.5;HBF TERT88: 1.2;U-2197: 1.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.18e-3)" "unprognostic (5.05e-3)" "unprognostic (6.66e-3)" "unprognostic (6.48e-5)" "unprognostic (1.04e-1)" "prognostic favorable (4.68e-5)" "unprognostic (1.12e-3)" "unprognostic (1.05e-2)" "unprognostic (7.15e-2)" "unprognostic (2.57e-3)" "unprognostic (6.40e-2)" "unprognostic (9.86e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (3.17e-1)" "unprognostic (6.65e-2)" "unprognostic (2.46e-2)" "unprognostic (1.06e-2)" 0.8 0.1 0.0 0.5 0.1 4.2 0.7 0.1 0.1 0.9 0.0 1.7 0.0 0.3 0.0 0.3 0.5 4.0 0.2 0.0 0.0 0.3 1.3 1.5 27.2 0.1 0.0 0.7 0.3 0.0 0.1 0.1 0.0 0.4 1.5 0.0 1.0 0.0 0.2 0.3 3.4 1.1 0.0 5.3 1.3 0.3 0.0 55.4 0.7 0.0 15.5 1.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.0 1.9 0.4 48.4 81.7 0.2 0.2 67.3 73.5 1.0 0.0 0.1 0.5 95.1 26.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 TRBV9 "TCRBV1S1A1N1, TCRBV9S1" ENSG00000211716 "T cell receptor beta variable 9" A0A0B4J1U6 7 142391891-142392412 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.1;testis: 2.6" "Group enriched" "Detected in some" 11 "Early spermatids: 5.8;Late spermatids: 4.8;T-cells: 7.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "memory CD4 T-cell: 20.0;memory CD8 T-cell: 21.7;naive CD4 T-cell: 14.8;naive CD8 T-cell: 13.2;T-reg: 27.2" "Lineage enriched" "Detected in single" 31 "T-cells: 27.2" "Group enriched" "Detected in some" 16 "HL-60: 3.4;LHCN-M2: 6.0;U-937: 13.3" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.28e-3)" "unprognostic (1.34e-2)" "unprognostic (1.73e-2)" "unprognostic (2.20e-3)" "unprognostic (3.00e-1)" "unprognostic (1.58e-4)" "unprognostic (8.88e-3)" "unprognostic (6.53e-2)" "unprognostic (1.20e-2)" "unprognostic (1.69e-3)" "unprognostic (2.98e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.60e-10)" "unprognostic (1.04e-1)" "unprognostic (7.94e-2)" "unprognostic (7.64e-3)" "unprognostic (1.46e-3)" 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.3 0.0 0.4 0.2 0.4 0.0 0.6 0.3 0.0 0.4 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.2 0.3 0.0 0.1 2.1 0.0 0.0 3.0 0.6 2.6 0.0 9.1 0.4 0.4 2.9 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 6.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 13.3 0.0 0.1 0.8 0.0 0.2 0.2 2.5 0.0 20.0 21.7 0.5 0.0 14.8 13.2 0.1 0.0 0.0 0.4 27.2 5.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 66.3" "Group enriched" "Detected in some" 5 "Late spermatids: 315.7;Proximal enterocytes: 186.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 12000000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favorable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" 0.7 0.2 1.6 0.3 3.7 0.0 0.4 0.6 3.8 0.3 0.0 1.6 60.0 0.4 0.6 1.6 0.3 2.6 1.0 1.1 2.7 13.4 6.1 0.2 0.1 2.1 2.0 0.2 1.8 0.0 0.3 0.1 1.9 0.5 1.3 0.0 0.2 0.0 0.0 0.1 66.3 0.1 0.6 0.1 1.7 1.8 2.5 0.0 0.4 0.0 0.0 0.4 0.3 6.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.7 0.6 3.8 1.1 2.7 2.1 2.0 1.9 0.6 2.5 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.3 0.3 1.5 0.0 1.8 0.0 0.1 0.0 2.3 7.9 0.2 45.6 0.8 1.6 0.1 3.0 0.0 0.1 2.5 0.0 0.3 4.6 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 7.0 0.0 0.0 0.4 315.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 5.3 0.9 6.3 1.9 0.1 0.3 186.3 32.8 0.0 0.0 0.0 0.3 0.2 1.7 0.8 2.1 0.0 0.0 0.1 0.0 3.7 0.0 TRGC1 "C1, TCRGC1" ENSG00000211689 "T cell receptor gamma constant 1" 7 38257879-38265678 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "bone marrow: 31.7;prostate: 76.6" "Group enriched" "Detected in some" 5 "dendritic cells: 95.8;NK-cells: 230.7;Prostatic glandular cells: 61.9;T-cells: 65.6" "Cancer enriched" "Detected in some" 141 "prostate cancer: 107.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "gdT-cell: 384.7" "Lineage enriched" "Detected in many" 4 "T-cells: 384.7" "Cell line enhanced" "Detected in some" "HL-60: 21.0;MCF7: 89.8;SK-BR-3: 49.6;U-937: 45.5" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.37e-2)" "unprognostic (2.38e-4)" "unprognostic (3.43e-3)" "unprognostic (6.04e-4)" "unprognostic (1.04e-2)" "unprognostic (3.77e-3)" "unprognostic (1.33e-3)" "unprognostic (3.80e-2)" "unprognostic (3.55e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (2.14e-1)" "unprognostic (2.15e-1)" "unprognostic (2.98e-1)" "unprognostic (8.36e-2)" "unprognostic (2.56e-2)" 0.6 0.2 1.6 1.1 1.6 31.7 2.1 1.4 2.0 0.1 1.1 0.5 1.0 0.2 0.5 0.1 0.3 1.0 0.2 1.4 1.4 0.8 0.8 1.9 2.0 1.7 1.5 0.1 0.0 0.0 0.2 0.5 1.6 76.6 0.6 0.0 0.4 0.2 0.1 0.1 1.4 0.2 1.6 6.0 0.6 0.4 2.1 7.0 0.3 0.0 1.3 0.6 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 21.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 89.8 0.2 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 49.6 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 45.5 0.0 3.8 0.3 0.5 384.7 0.4 56.7 0.2 6.8 33.5 0.3 0.0 2.3 21.7 1.8 87.5 0.3 0.5 0.1 43.7 1.6 1.6 1.4 2.0 1.4 1.4 1.7 1.5 1.6 1.6 2.1 1.5 0.5 0.0 1.1 0.0 2.1 0.0 1.3 0.0 0.0 0.0 1.8 0.6 0.2 0.0 0.6 0.0 0.0 0.0 95.8 0.1 0.0 0.0 2.3 0.0 0.1 0.5 1.2 2.7 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.0 2.2 0.9 0.1 0.0 0.0 0.2 0.0 1.9 0.0 0.9 0.0 2.1 0.0 0.0 19.5 0.0 230.7 0.0 0.0 0.0 0.0 0.0 14.3 61.9 0.0 0.3 0.7 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 65.6 0.0 0.3 1.2 TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 34.6;prostate: 23.7" "Group enriched" "Detected in some" 7 "dendritic cells: 149.1;NK-cells: 90.6;T-cells: 122.0" "Cancer enriched" "Detected in many" 18 "prostate cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 720.5" "Lineage enriched" "Detected in many" 5 "T-cells: 720.5" "Cell line enhanced" "Detected in some" "HL-60: 11.4;JURKAT: 36.6;NB-4: 29.9;SK-BR-3: 9.8;U-937: 53.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.79e-3)" "prognostic favorable (1.06e-5)" "unprognostic (1.62e-4)" "unprognostic (3.52e-5)" "unprognostic (3.34e-1)" "unprognostic (1.46e-3)" "unprognostic (8.79e-4)" "unprognostic (4.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-3)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-3)" 3.6 1.1 8.8 5.1 9.0 30.5 1.8 8.6 19.6 1.5 7.1 3.5 4.5 1.3 3.2 1.1 2.2 3.9 0.9 8.4 8.5 1.6 3.6 9.7 17.5 9.6 8.9 0.5 0.8 0.2 1.0 0.5 9.2 23.7 4.0 0.1 1.8 0.8 0.4 0.6 8.0 1.0 9.3 29.7 3.8 2.2 10.2 34.6 2.1 0.1 7.0 3.4 2.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 3.7 1.2 29.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.9 0.0 1.1 1.3 1.4 720.5 1.2 287.4 0.6 64.8 341.6 1.0 0.3 13.5 212.9 4.9 149.7 1.0 1.2 1.3 167.5 8.8 9.0 8.6 19.6 8.4 8.5 9.6 8.9 9.2 9.3 10.2 9.5 1.2 0.0 2.4 0.0 2.4 0.0 0.2 0.0 0.0 0.0 1.0 1.3 0.7 1.5 0.6 0.0 0.0 0.0 149.1 0.3 0.0 0.2 15.5 0.2 0.1 0.8 0.0 6.6 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.2 3.9 1.0 0.0 0.0 0.0 0.5 0.0 3.5 0.0 6.7 0.0 2.8 0.0 0.0 10.6 0.0 90.6 0.0 0.0 0.0 0.0 0.4 14.2 2.8 0.0 0.5 0.0 0.0 0.0 0.2 1.3 0.8 0.2 0.3 0.0 0.3 122.0 0.0 0.2 0.3 TRGV10 "TCRGV10, V3P" ENSG00000211694 "T cell receptor gamma variable 10 (non-functional)" 7 38299811-38300322 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.5;Plasma cells: 7.1;T-cells: 29.9" "Cancer enriched" "Detected in many" 8 "prostate cancer: 7.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 196.5" "Lineage enriched" "Detected in many" 8 "T-cells: 196.5" "Group enriched" "Detected in some" 24 "NB-4: 79.7;U-937: 20.5" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.59e-2)" "unprognostic (4.53e-3)" "unprognostic (5.13e-2)" "unprognostic (2.94e-3)" "unprognostic (1.54e-2)" "unprognostic (1.22e-4)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.53e-2)" "unprognostic (1.94e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-4)" "unprognostic (2.68e-1)" "unprognostic (9.00e-2)" "unprognostic (5.10e-2)" "unprognostic (2.07e-2)" 1.7 0.6 0.1 2.7 0.3 14.1 1.8 0.1 0.4 1.2 0.6 2.0 2.1 0.8 0.7 1.1 1.3 3.3 0.4 0.0 0.1 0.6 1.8 4.1 11.0 0.4 0.1 0.3 0.2 0.1 0.2 0.4 0.3 6.1 2.7 0.0 1.1 0.7 0.2 0.6 4.1 0.6 0.2 13.9 2.6 0.3 0.2 12.5 1.1 0.0 5.0 3.8 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 79.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.5 0.0 0.7 0.4 1.0 196.5 0.1 156.1 0.5 47.2 137.6 0.2 0.1 11.3 159.7 2.9 26.0 0.3 0.8 0.1 33.3 0.1 0.3 0.1 0.4 0.0 0.1 0.4 0.1 0.3 0.2 0.2 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 29.9 0.0 0.0 0.0 TRGV2 "TCRGV2, VIS2" ENSG00000233306 "T cell receptor gamma variable 2" A0A075B6R0 7 38362864-38363518 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 6.6" "Cell type enriched" "Detected in some" 5 "T-cells: 19.2" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 147.8" "Lineage enriched" "Detected in many" 22 "T-cells: 147.8" "Cell line enriched" "Detected in some" 4 "Karpas-707: 17.4" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.51e-3)" "unprognostic (8.88e-5)" "unprognostic (1.77e-1)" "unprognostic (1.01e-2)" "unprognostic (1.72e-1)" "unprognostic (4.31e-4)" "unprognostic (1.50e-3)" "unprognostic (1.13e-1)" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (7.48e-2)" "unprognostic (3.02e-1)" "unprognostic (4.21e-5)" "unprognostic (1.43e-2)" "unprognostic (1.96e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-3)" 0.4 0.6 0.0 1.6 0.0 0.9 0.1 0.0 0.2 0.2 0.2 0.8 0.8 0.3 0.1 0.1 0.3 1.0 0.2 0.0 0.0 0.1 0.3 0.9 5.0 0.7 0.4 0.0 0.1 0.0 0.1 0.0 0.2 1.2 0.6 0.1 0.9 0.1 0.1 0.2 1.4 0.4 0.1 6.6 0.7 0.3 0.4 4.8 0.3 0.0 0.7 0.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 2.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 1.0 17.4 0.0 0.0 0.5 0.8 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.7 1.7 0.1 0.0 3.8 0.0 0.2 0.4 0.0 59.4 0.2 58.4 0.1 29.7 147.8 1.4 0.2 7.0 54.9 0.9 6.8 0.1 1.5 0.6 22.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 TRGV3 "TCRGV3, V1S3" ENSG00000211699 "T cell receptor gamma variable 3" P03979 7 38358512-38359162 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 12.4" "Cell type enhanced" "Detected in some" "dendritic cells: 1.8;Plasma cells: 2.6;T-cells: 5.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 59.0" "Lineage enriched" "Detected in many" 5 "T-cells: 59.0" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;JURKAT: 12.1;Karpas-707: 28.9;U-266/84: 5.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.87e-2)" "unprognostic (1.63e-3)" "unprognostic (4.58e-2)" "unprognostic (6.48e-3)" "unprognostic (4.66e-2)" "unprognostic (1.57e-3)" "unprognostic (2.28e-1)" "unprognostic (1.72e-2)" "unprognostic (1.49e-1)" "unprognostic (4.46e-2)" "unprognostic (4.75e-2)" "unprognostic (1.46e-1)" "unprognostic (5.26e-3)" "unprognostic (2.28e-1)" "unprognostic (3.46e-2)" "unprognostic (3.71e-2)" "unprognostic (3.42e-2)" 0.6 0.3 0.1 1.3 0.1 2.8 0.5 0.1 0.2 0.7 0.1 1.8 1.0 0.6 0.0 0.5 0.6 3.9 0.3 0.1 0.3 0.4 0.7 1.4 12.4 0.7 1.3 0.1 0.2 0.3 0.2 1.0 0.4 1.3 1.9 0.0 1.1 0.4 0.1 0.3 3.1 0.7 0.5 7.6 1.3 0.5 0.5 9.3 0.4 0.0 8.9 2.0 0.3 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 7.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 3.8 12.1 0.7 28.9 0.0 0.2 0.0 1.4 0.2 0.0 0.0 1.5 1.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 3.1 0.8 0.0 0.0 0.0 0.1 3.0 5.9 0.4 0.1 1.6 0.0 0.1 1.6 0.0 59.0 0.7 50.1 3.4 11.0 34.0 5.7 1.8 9.4 27.6 0.1 11.4 2.2 11.1 6.3 8.0 0.1 0.1 0.1 0.2 0.1 0.3 0.7 1.3 0.4 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670758 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;pancreas: 10.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 216.9;Inhibitory neurons: 292.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Group enriched" "Detected in many" 5 "basal ganglia: 4.9;cerebellum: 4.4;cerebral cortex: 2.5;hippocampal formation: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 30.3;BJ hTERT+: 29.1;EFO-21: 15.3;HBF TERT88: 10.3;hTERT-RPE1: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 7300000 "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favorable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" 3.6 0.9 0.1 0.3 4.9 0.4 0.8 4.4 2.5 3.7 0.0 1.1 2.4 1.2 0.6 0.2 1.1 0.8 0.8 7.6 0.0 5.1 0.5 1.4 0.1 0.0 0.9 3.2 10.3 0.0 0.1 0.1 0.0 1.3 0.5 0.8 0.8 2.8 0.2 0.2 2.1 0.4 0.0 2.5 0.3 0.7 0.0 0.1 0.0 0.4 0.3 1.2 2.3 0.0 3.6 0.0 0.6 0.0 1.6 0.0 9.5 30.3 29.1 2.9 1.9 0.0 0.0 0.0 15.3 4.3 3.0 0.4 5.4 0.0 10.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 2.3 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.7 0.0 0.0 0.0 9.5 6.7 2.9 0.1 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.9 4.4 2.5 7.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.5 2.9 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 1.5 0.0 1.8 0.0 0.1 0.0 7.1 3.9 0.0 35.9 0.1 0.4 0.2 0.0 0.0 216.9 2.6 0.4 4.7 0.0 0.3 0.0 0.1 0.4 1.4 0.2 0.0 292.7 3.5 0.0 0.0 0.0 62.8 29.5 0.7 0.0 2.8 0.0 0.4 0.0 38.2 4.0 2.2 3.9 13.5 0.0 0.2 15.8 9.1 0.7 0.6 0.0 37.4 0.6 0.2 0.7 0.0 0.0 0.1 0.1 0.2 1.6 0.1 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 104.3;Muller glia cells: 100.3" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.8" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.8" "Cell line enhanced" "Detected in many" "AN3-CA: 183.5;HEL: 185.7;K-562: 258.0;SK-MEL-30: 189.3;WM-115: 246.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 43.3 63.1 29.1 38.9 29.9 16.8 38.3 36.1 35.2 21.7 30.5 27.0 17.8 44.4 43.4 15.5 23.4 28.8 51.0 31.6 37.7 92.3 21.0 39.8 72.7 31.4 30.8 97.8 26.2 18.0 20.0 46.6 29.7 33.0 13.4 137.8 20.4 25.6 14.3 16.9 25.2 34.2 29.7 79.7 41.8 28.5 32.4 39.3 23.9 19.5 69.6 48.4 19.5 28.0 0.2 0.4 138.8 183.5 48.9 44.7 0.2 7.9 7.5 4.9 7.9 0.9 15.3 16.3 5.5 16.9 0.8 2.3 10.3 16.1 4.2 18.3 28.9 185.7 0.4 2.7 60.7 10.7 68.0 41.7 16.0 20.3 5.6 48.9 22.1 23.8 258.0 0.3 7.9 1.7 24.4 44.8 66.1 7.0 18.0 0.0 46.2 6.7 31.9 23.4 118.9 56.6 1.1 7.4 189.3 41.4 0.2 1.1 13.9 65.3 32.0 0.6 17.8 0.1 0.2 22.9 35.2 36.3 246.7 1.7 0.2 3.2 12.7 0.0 15.8 9.6 26.1 13.8 1.2 12.2 15.0 9.2 0.5 19.3 0.2 0.1 48.8 8.9 29.1 29.9 36.1 35.2 31.6 37.7 31.4 30.8 29.7 29.7 32.4 28.0 52.2 3.2 8.3 25.5 12.5 6.1 9.1 26.9 19.4 55.0 7.9 8.6 17.1 12.8 15.6 16.5 31.3 2.6 17.5 0.7 7.9 17.2 4.3 9.7 11.6 43.9 0.0 22.1 13.5 104.3 0.2 11.3 20.9 15.9 34.2 77.3 59.6 6.7 5.8 20.2 6.9 0.4 28.5 5.1 8.2 14.3 77.3 3.8 30.2 13.1 3.0 100.3 26.8 59.8 2.7 45.3 0.2 74.4 21.0 11.6 0.3 1.0 17.9 66.7 52.6 9.9 41.2 1.0 6.0 5.7 5.4 0.8 27.1 30.5 0.8 32.5 TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.5" "Cell type enhanced" "Detected in many" "Ductal cells: 53.1;Hepatocytes: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 630.3;hTCEpi: 401.9;hTERT-HME1: 461.8;SK-MEL-30: 615.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA015272: AB_1858269, HPA055442: AB_2682818" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.70e-4)" "prognostic unfavorable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" 8.0 16.4 5.6 4.0 5.4 16.1 7.8 6.0 6.7 4.4 6.5 4.4 1.3 2.9 3.0 20.5 2.2 2.6 4.0 5.1 6.5 9.9 80.5 15.4 6.5 5.5 5.5 3.2 17.3 13.3 15.2 8.4 5.6 7.8 2.2 2.7 10.4 3.0 1.8 13.6 5.3 1.8 4.4 12.1 10.2 1.4 6.7 5.6 38.2 0.5 5.9 4.8 5.3 4.4 80.9 41.6 5.1 11.9 13.7 17.9 33.7 23.9 65.8 23.0 47.5 86.7 40.0 35.3 22.2 22.5 102.3 62.6 22.6 107.7 21.4 12.4 16.2 27.5 8.9 144.2 630.3 71.5 12.7 73.3 401.9 43.5 461.8 16.2 45.1 86.1 97.3 155.2 2.3 77.3 4.2 87.0 11.8 122.8 133.0 15.2 7.1 77.1 27.0 33.3 14.7 23.0 5.6 192.2 615.5 7.2 55.7 185.6 24.6 11.7 20.6 0.3 36.2 52.3 73.9 63.5 10.5 61.4 43.6 5.1 6.4 1.4 13.2 4.9 9.4 21.0 12.3 15.3 6.7 13.8 13.7 9.8 4.4 10.2 2.6 2.8 9.7 7.8 5.6 5.4 6.0 6.7 5.1 6.5 5.5 5.5 5.6 4.4 6.7 4.4 7.9 3.2 1.5 0.3 9.3 6.8 10.9 20.3 3.4 6.8 12.7 8.3 1.6 11.5 8.5 1.8 4.2 14.1 4.0 3.4 0.0 53.1 0.0 0.2 1.6 15.8 1.2 5.7 2.2 22.7 6.4 3.9 0.0 2.6 5.1 0.5 6.8 38.4 6.4 0.0 3.1 8.8 6.1 3.3 4.4 0.0 1.8 3.0 7.2 0.0 4.2 1.0 14.4 1.0 0.6 24.0 1.9 1.5 10.0 12.2 0.0 0.1 2.9 7.0 6.6 6.5 6.9 2.4 3.1 4.0 5.4 7.1 5.7 3.5 2.2 6.7 TRIM11 "BIA1, RNF92" ENSG00000154370 "Tripartite motif containing 11" Q96F44 1 228393673-228406835 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 154.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028541, HPA043879" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA028541: AB_10600833, HPA043879: AB_2678711" "unprognostic (1.73e-1)" "unprognostic (9.73e-3)" "unprognostic (5.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.27e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (7.42e-5)" "unprognostic (1.08e-1)" "unprognostic (9.74e-2)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.89e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" 10.2 12.1 12.7 8.9 16.0 30.7 10.4 23.9 15.2 14.7 10.1 13.6 7.7 11.5 4.5 20.7 12.7 6.1 8.7 14.4 11.6 12.2 10.2 11.8 12.2 11.6 9.9 11.9 11.9 6.7 9.8 5.6 10.8 15.4 7.1 2.0 17.1 7.0 5.0 17.1 14.6 4.6 8.6 24.1 12.9 14.9 13.2 10.1 11.0 3.1 8.7 11.7 15.6 11.0 28.3 26.3 13.8 19.1 10.2 8.4 65.1 18.1 12.1 20.5 16.4 32.2 24.0 21.1 19.7 12.2 13.5 45.1 16.8 17.4 8.6 23.6 40.5 17.5 26.7 17.6 27.6 22.2 25.6 11.3 27.2 21.3 10.6 10.5 10.2 33.9 40.7 26.4 10.7 18.2 27.1 35.1 35.3 23.9 22.9 26.3 12.5 25.8 13.4 34.0 22.9 42.0 15.1 42.2 24.7 5.6 29.9 36.8 11.6 13.0 18.3 30.6 37.9 26.9 19.3 18.9 16.1 17.7 20.9 5.2 4.5 5.6 5.5 5.3 5.9 3.7 6.4 7.1 4.4 3.5 3.6 5.1 6.2 6.2 7.5 3.5 6.4 3.9 12.7 16.0 23.9 15.2 14.4 11.6 11.6 9.9 10.8 8.6 13.2 11.0 7.8 3.2 5.8 1.6 12.1 15.8 16.3 7.4 10.8 12.1 13.3 10.7 3.6 12.8 10.4 1.8 2.1 15.7 21.6 28.1 17.6 14.8 154.2 11.2 10.2 10.1 14.4 12.6 9.8 11.0 15.5 8.5 23.4 17.1 5.7 13.4 8.9 5.7 11.8 5.0 4.7 21.7 4.1 12.6 9.3 16.5 9.6 11.0 5.4 2.8 22.0 10.3 30.9 3.0 3.2 18.3 21.1 7.5 12.8 17.4 17.8 9.9 7.3 1.6 6.6 8.4 9.1 7.3 12.4 15.8 19.5 57.3 18.9 14.9 17.6 30.1 TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 600.1;skin 1: 551.2;vagina: 269.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.0;Basal squamous epithelial cells: 250.4;Late spermatids: 150.3;Squamous epithelial cells: 552.9;Suprabasal keratinocytes: 460.6;Urothelial cells: 159.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 399.9;HBEC3-KT: 107.5;hTCEpi: 476.0;RT4: 190.5;SiHa: 268.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 4.0" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" 2.5 1.0 0.1 0.4 0.2 0.4 41.7 0.0 0.4 133.8 1.6 3.0 1.7 2.6 4.8 600.1 17.4 3.5 0.4 0.3 0.0 1.7 1.8 3.7 0.0 1.8 0.6 0.4 1.0 0.0 8.1 30.7 1.8 31.4 2.6 0.3 131.5 23.7 2.2 551.2 1.0 1.5 2.6 0.3 1.4 2.7 0.0 19.9 0.4 0.2 107.2 55.8 269.1 0.6 34.4 2.5 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.2 0.1 0.8 25.6 0.2 3.9 0.2 0.5 399.9 0.0 107.5 0.0 0.1 0.0 0.2 25.4 0.4 0.0 0.2 0.5 0.0 476.0 0.0 2.6 0.0 0.0 0.0 0.2 0.7 0.0 4.4 0.0 0.0 0.1 11.4 0.1 0.0 0.3 0.0 0.3 190.5 1.3 5.9 268.3 35.2 0.1 0.2 1.9 0.0 0.4 0.1 2.1 0.2 0.1 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.3 0.0 1.8 0.6 1.8 2.6 0.0 0.6 0.5 0.0 1.5 3.3 0.2 272.0 106.1 76.4 250.4 0.0 9.5 58.8 1.2 1.5 39.2 0.0 0.0 41.0 0.2 11.3 0.0 5.0 28.1 8.7 0.8 3.4 2.4 0.0 0.5 4.3 7.1 5.6 1.1 3.6 1.3 0.0 0.0 0.4 5.0 0.0 0.1 2.1 12.2 0.0 30.3 150.3 0.6 1.4 23.2 1.0 0.0 0.0 0.0 0.0 0.1 57.1 11.3 0.0 0.0 66.0 0.2 0.6 64.6 0.0 0.0 0.1 4.9 0.8 2.6 552.9 460.6 24.8 2.4 0.1 3.7 159.3 TRIM3 "BERP, HAC1, RNF22, RNF97" ENSG00000110171 "Tripartite motif containing 3" O75382 11 6448613-6474459 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043396, HPA048233" Enhanced Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA043396: AB_2678460, HPA048233: AB_2680321" "unprognostic (1.24e-1)" "unprognostic (1.98e-1)" "unprognostic (2.31e-1)" "prognostic favorable (2.20e-4)" "unprognostic (4.01e-2)" "unprognostic (3.88e-2)" "unprognostic (1.61e-3)" "unprognostic (2.84e-1)" "unprognostic (2.24e-1)" "unprognostic (3.91e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.01e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.93e-1)" 9.5 4.6 6.4 4.6 6.2 1.3 10.3 11.6 7.5 11.2 0.0 13.0 17.8 13.5 1.8 4.8 10.1 4.1 8.0 5.8 3.4 6.3 6.3 9.7 2.4 8.5 3.1 8.7 6.4 2.7 5.9 3.9 9.4 9.5 4.8 4.8 9.0 5.4 11.5 8.4 15.7 5.6 2.2 5.7 10.1 3.8 5.9 1.5 6.8 4.8 1.6 11.2 9.3 6.1 7.2 12.4 4.9 8.3 8.1 7.8 6.7 10.3 6.1 7.8 8.6 7.6 5.0 3.9 3.6 7.9 9.1 5.0 5.1 7.7 3.0 4.8 7.6 1.2 13.5 5.3 5.2 0.4 4.1 6.7 3.7 6.1 3.2 3.3 8.0 2.9 1.7 4.7 7.8 15.2 0.3 1.0 3.5 15.2 10.7 2.4 4.2 4.9 1.9 3.8 5.1 7.8 5.7 54.9 6.6 2.5 20.8 1.3 13.4 20.3 9.5 15.0 6.9 5.5 3.6 0.8 11.0 1.7 7.6 0.0 1.0 0.6 0.5 1.0 0.4 0.1 0.4 0.4 1.2 0.1 0.1 0.6 0.0 0.6 0.2 0.2 0.5 0.5 6.4 6.2 11.6 7.5 5.8 3.4 8.5 3.1 9.4 2.2 5.9 6.1 8.5 6.4 0.0 9.8 2.4 4.8 2.8 2.8 3.4 8.8 8.5 6.0 2.2 2.8 2.7 0.0 10.4 1.8 3.5 16.0 0.0 3.1 3.9 2.8 4.4 6.5 4.8 0.4 13.2 3.5 2.2 6.9 5.6 7.3 1.3 3.6 4.6 2.5 4.7 8.4 12.2 11.4 4.1 0.8 6.5 5.6 5.9 3.5 7.2 11.2 3.4 2.2 3.1 5.0 10.2 3.1 5.4 5.3 2.5 3.2 28.7 3.1 8.4 9.6 13.1 5.0 11.3 3.1 6.0 3.7 5.4 0.8 3.4 3.3 6.6 2.3 TRIM61 RNF35 ENSG00000183439 "Tripartite motif containing 61" Q5EBN2 4 164954446-164977668 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 34.5;Late spermatids: 14.0;Spermatocytes: 50.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 15.1;SuSa: 10.2;U-266/70: 17.2" "Not detected" "Not detected" HPA049109 Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA049109: AB_2680636" "unprognostic (2.05e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (1.02e-2)" "unprognostic (8.24e-2)" "unprognostic (1.51e-2)" "unprognostic (1.38e-1)" "unprognostic (2.98e-2)" "unprognostic (7.81e-2)" "unprognostic (1.51e-1)" "unprognostic (3.67e-1)" "unprognostic (2.92e-1)" "unprognostic (9.77e-5)" "unprognostic (4.61e-2)" "unprognostic (2.51e-1)" "unprognostic (1.36e-1)" "unprognostic (4.32e-2)" 2.1 3.6 1.9 2.2 2.2 3.7 1.3 2.2 2.3 2.9 0.3 1.3 1.9 1.5 2.1 1.0 3.5 2.9 3.0 1.8 3.1 1.0 1.1 2.2 3.2 2.4 2.6 5.0 1.4 1.1 1.0 1.7 2.3 1.8 1.4 2.7 0.9 2.0 0.9 1.1 1.4 2.2 1.7 2.1 1.3 8.9 2.5 2.6 5.6 1.4 2.9 2.3 0.2 2.7 0.9 0.8 2.0 2.1 1.1 1.1 1.2 4.2 1.3 0.9 0.8 0.7 1.4 0.9 1.1 5.3 1.0 1.0 1.4 1.5 0.9 1.6 0.8 1.6 1.5 0.9 15.1 1.6 1.4 9.0 1.3 3.7 1.4 8.5 0.8 1.3 1.8 3.6 0.8 1.0 1.4 1.0 6.5 1.0 0.7 1.4 1.1 1.2 0.6 2.6 1.7 1.1 1.0 1.5 1.2 10.2 0.5 1.6 0.9 2.7 1.8 0.9 1.7 17.2 8.2 2.3 1.0 0.9 1.9 5.4 1.4 0.1 2.9 1.2 3.3 3.5 1.8 3.3 1.5 5.8 4.4 3.6 0.3 8.0 1.1 4.1 0.8 1.4 1.9 2.2 2.2 2.3 1.8 3.1 2.4 2.6 2.3 1.7 2.5 2.7 0.2 0.0 3.3 1.0 3.8 0.3 1.2 0.4 0.0 1.1 0.1 0.1 2.3 0.0 0.2 3.7 4.2 0.3 2.3 0.0 0.0 0.3 34.5 0.4 2.1 0.9 0.0 1.3 1.9 0.7 0.0 1.6 0.5 0.1 0.0 4.8 0.0 0.4 1.1 1.7 1.4 0.0 0.0 0.6 0.7 14.0 1.2 0.9 0.0 0.0 1.7 2.7 1.0 3.5 4.3 0.1 0.1 1.5 6.4 0.6 0.0 3.7 0.1 0.4 0.0 1.5 1.3 50.1 3.7 0.2 0.0 0.3 2.2 2.8 0.0 0.6 TRIM62 "DEAR1, FLJ10759" ENSG00000116525 "Tripartite motif containing 62" Q9BVG3 1 33145399-33182059 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.0" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AF22: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050061 Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "Vesicles, Focal adhesion sites" "HPA050061: AB_2681001" "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (2.62e-2)" "unprognostic (1.14e-2)" "unprognostic (5.80e-2)" "unprognostic (5.10e-5)" "unprognostic (2.05e-2)" "unprognostic (1.14e-1)" "unprognostic (4.32e-2)" "unprognostic (3.55e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (2.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-3)" 3.1 6.6 8.7 2.9 13.1 4.8 3.6 10.0 11.9 3.2 2.3 3.2 2.4 3.1 2.6 5.1 3.0 2.0 3.5 8.5 10.4 3.5 1.8 3.1 4.6 10.7 11.3 3.7 3.1 2.9 6.4 3.4 12.1 5.1 2.1 2.1 5.2 2.9 4.9 12.5 4.2 2.8 7.4 5.1 4.3 2.3 12.4 5.2 3.9 2.5 4.5 4.8 4.4 21.0 3.7 2.7 23.9 3.9 5.7 2.5 7.6 3.4 9.9 6.3 5.5 3.0 3.7 5.9 3.8 3.0 3.2 7.2 5.0 4.3 5.6 5.8 3.8 6.5 3.2 2.5 5.7 2.2 16.2 5.2 3.9 8.7 2.0 9.9 6.3 5.0 1.1 3.8 6.1 9.9 6.8 2.0 6.0 4.3 3.5 8.6 12.8 2.7 3.8 9.6 6.0 3.7 3.8 14.5 16.8 12.6 4.1 1.4 6.3 2.7 3.8 8.1 2.8 6.9 3.3 2.7 5.1 3.9 3.5 1.2 1.0 3.4 1.3 1.8 2.3 1.1 1.9 1.8 0.9 1.4 1.3 1.2 2.3 1.0 1.1 0.4 4.7 1.1 8.7 13.1 10.0 11.9 8.5 10.4 10.7 11.3 12.1 7.4 12.4 21.0 2.0 3.2 2.2 2.6 1.8 2.7 0.8 1.7 2.8 3.4 3.5 1.9 0.9 0.0 1.2 1.8 0.0 1.1 2.5 1.5 0.0 1.4 0.5 0.6 1.1 1.4 1.8 0.4 1.9 1.9 1.8 2.1 4.1 1.3 1.3 1.7 1.1 0.7 1.2 10.1 10.2 1.5 4.1 1.2 1.6 0.5 2.5 1.3 0.0 10.3 1.4 1.5 3.1 50.8 26.0 2.6 0.6 4.9 2.6 2.1 1.2 1.0 0.4 1.0 6.6 2.0 2.1 1.3 0.6 2.8 4.7 1.4 3.0 3.4 0.9 2.0 TRIM67 TNL ENSG00000119283 "Tripartite motif containing 67" Q6ZTA4 1 231162112-231221556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 8.5;retina: 3.5" "Group enriched" "Detected in some" 4 "Horizontal cells: 69.0;Inhibitory neurons: 24.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034776 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA034776: AB_10603997" "unprognostic (1.56e-3)" "unprognostic (1.54e-1)" "unprognostic (5.20e-2)" "unprognostic (5.39e-3)" "unprognostic (2.95e-1)" "unprognostic (3.82e-2)" "unprognostic (6.02e-2)" "unprognostic (4.63e-3)" "unprognostic (1.84e-2)" "unprognostic (1.74e-1)" "unprognostic (4.93e-10)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (4.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.30e-2)" "unprognostic (5.10e-3)" 0.0 0.2 1.0 0.0 0.8 0.0 0.0 8.5 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.4 1.5 0.0 0.0 0.0 0.0 3.5 1.5 0.0 0.0 0.0 0.5 0.1 2.7 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 8.5 2.2 1.4 1.5 3.5 1.5 2.7 1.7 1.5 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.0 24.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.5 0.0 6.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143342-14532128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 205.7;Excitatory neurons: 400.9;Inhibitory neurons: 443.4;Microglial cells: 308.2;Oligodendrocyte precursor cells: 476.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 215.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: AB_2685315" "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 35.3 20.5 31.7 11.6 33.3 5.5 31.8 32.2 38.6 23.4 34.5 36.6 6.8 38.9 15.5 14.5 21.2 18.8 31.9 37.2 33.6 24.9 22.1 25.7 10.2 28.1 28.1 52.8 20.6 9.1 28.9 11.6 26.6 28.2 13.6 10.2 17.4 11.1 20.9 18.7 27.8 19.2 26.4 38.9 22.9 17.2 31.4 13.3 17.0 17.4 10.6 27.1 20.5 27.2 43.7 15.9 37.2 18.0 78.6 101.0 41.3 40.4 49.2 32.6 36.9 10.3 17.4 10.4 28.0 56.6 79.6 13.0 6.5 19.4 66.6 25.8 8.0 5.5 46.1 13.2 40.0 13.9 14.8 47.6 19.9 114.4 36.4 30.3 28.8 6.8 1.4 6.8 78.7 8.3 0.1 9.5 9.3 4.8 13.7 9.9 22.9 34.2 31.6 20.5 17.1 67.5 34.3 9.0 18.9 47.1 5.3 2.0 66.4 61.4 38.3 44.7 48.4 0.3 2.2 12.9 215.1 8.8 14.8 0.1 0.5 0.0 0.0 0.7 0.1 0.7 0.0 0.0 0.5 1.8 0.0 0.0 0.0 1.6 0.6 1.1 0.3 0.1 31.7 33.3 32.2 38.6 37.2 33.6 28.1 28.1 26.6 26.4 31.4 27.2 33.0 19.2 25.9 205.7 16.6 16.4 13.0 15.6 17.1 30.5 21.9 15.0 19.3 10.0 21.0 11.0 14.6 9.7 5.6 24.8 0.0 21.2 2.9 11.7 24.8 28.7 18.0 6.5 400.9 14.2 22.0 38.9 7.7 34.2 17.7 17.2 14.6 17.1 14.2 28.6 443.4 20.6 14.2 15.4 22.1 6.6 78.6 20.2 5.4 308.2 12.1 7.3 2.1 476.5 80.4 38.5 14.9 42.9 29.2 52.8 9.2 5.4 18.3 2.7 6.6 27.5 20.0 3.5 6.2 7.2 13.8 8.2 3.8 11.7 19.4 20.3 TRPC3 ENSG00000138741 "Transient receptor potential cation channel subfamily C member 3" Q13507 4 121874481-121952060 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;pituitary gland: 7.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;Inhibitory neurons: 82.7;Oligodendrocyte precursor cells: 33.7;Rod photoreceptor cells: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 2.3;Karpas-707: 2.6;U-2 OS: 1.5;U-251 MG: 1.5" "Region enhanced" "Detected in all" "cerebellum: 57.8" "Low region specificity" "Detected in many" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (2.39e-1)" "unprognostic (3.12e-2)" "unprognostic (5.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.12e-3)" "unprognostic (9.80e-2)" "unprognostic (4.80e-3)" "unprognostic (2.38e-1)" "unprognostic (3.26e-1)" "unprognostic (1.06e-1)" "unprognostic (4.33e-3)" "unprognostic (2.67e-3)" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (8.42e-3)" 0.3 0.0 2.3 0.1 4.0 0.0 0.2 4.6 5.8 0.8 0.1 0.2 0.1 0.4 0.2 0.0 0.5 0.8 0.2 0.8 3.2 0.1 0.1 0.9 0.1 10.4 2.8 0.1 0.0 0.2 7.4 1.1 2.2 0.2 0.1 3.9 0.1 0.6 0.4 0.1 0.5 2.6 1.6 0.2 0.2 0.4 4.6 0.0 0.1 0.2 0.0 1.7 0.7 1.7 0.0 0.0 0.8 0.1 0.1 0.1 0.0 0.4 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.4 0.0 0.1 0.0 1.3 2.3 0.2 0.0 0.1 0.7 0.3 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 2.6 0.5 0.1 0.8 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 1.2 1.5 0.1 1.5 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.3 4.0 4.6 5.8 0.8 3.2 10.4 2.8 2.2 1.6 4.6 1.7 0.5 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.0 8.4 0.0 0.5 0.0 0.0 0.0 2.3 0.0 0.3 0.2 0.0 0.0 18.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 82.7 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.1 4.6 0.0 33.7 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 32.0 0.0 0.3 1.4 0.5 0.8 0.0 0.0 0.0 0.5 0.5 0.0 0.1 TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001061-31161273 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 9.4;skin 1: 4.1" "Group enriched" "Detected in some" 7 "Bipolar cells: 627.4;Melanocytes: 158.3" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 112 "SK-MEL-30: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.4 0.1 0.0 0.0 4.1 0.0 0.0 0.5 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.2 0.2 0.4 0.3 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.0 4.2 0.0 0.0 0.0 627.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 50.5 0.1 0.1 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 13.5 0.8 0.0 0.0 0.0 1.0 6.3 0.0 0.0 158.3 0.0 0.0 11.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 22.2 0.0 0.1 0.1 10.1 4.4 1.8 1.0 1.0 0.0 0.0 0.0 0.1 TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 50.0;Hofbauer cells: 50.6;monocytes: 39.4;NK-cells: 49.4" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 78.8;fHDF/TERT166: 108.4;HMC-1: 89.0;SK-MEL-30: 94.7;TIME: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" 17.1 20.5 6.2 18.3 8.0 22.8 10.4 5.7 7.6 7.9 3.9 7.0 6.6 7.6 1.8 5.3 7.3 8.5 11.2 6.1 9.8 4.7 4.0 30.2 24.6 10.6 15.4 7.8 6.3 8.9 1.6 20.1 17.2 6.0 6.2 1.0 4.5 2.6 3.9 6.5 10.7 11.8 7.1 23.7 5.9 2.0 7.3 15.7 6.2 5.5 16.2 10.7 7.2 8.0 0.3 1.6 0.0 0.0 25.6 78.8 4.9 8.3 9.4 9.1 8.9 0.3 0.3 9.6 2.2 108.4 7.8 0.2 0.2 0.0 5.1 43.0 0.7 10.7 0.0 26.1 30.0 14.8 89.0 35.2 0.0 54.0 0.7 4.1 3.8 12.9 37.2 26.0 43.4 0.5 19.1 20.5 0.1 0.1 0.2 11.3 0.3 4.3 40.6 1.1 1.2 0.1 0.0 0.0 94.7 41.0 0.0 12.7 84.9 0.2 0.3 0.3 1.1 0.1 0.3 5.1 8.2 21.6 12.6 60.8 26.6 35.8 63.4 52.8 55.5 19.2 46.0 59.3 58.7 20.3 25.7 44.8 6.8 63.2 49.4 51.3 49.9 43.1 6.2 8.0 5.7 7.6 6.1 9.8 10.6 15.4 17.2 7.1 7.3 8.0 15.8 0.0 5.3 1.0 11.1 2.8 0.1 0.0 0.0 0.6 0.5 0.4 1.1 1.5 0.6 0.0 0.0 2.2 29.3 0.0 0.0 0.2 0.3 0.4 0.1 12.3 0.0 6.7 3.3 3.6 2.3 11.0 1.1 0.1 50.0 16.7 8.9 0.4 50.6 0.0 2.6 0.0 0.0 19.5 18.2 0.0 1.8 28.7 28.4 4.7 39.4 0.3 49.4 0.5 0.5 4.7 0.1 4.5 15.1 0.0 0.0 0.1 0.8 0.6 26.3 7.9 23.6 1.3 5.9 0.4 1.7 16.1 26.8 2.8 0.0 0.1 TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 237.3" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 506.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 168.0;ASC diff: 282.5;OE19: 188.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" NA NA 6200000 "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nuclear bodies" "HPA008164: AB_1853327" "unprognostic (1.07e-2)" "unprognostic (2.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (3.66e-4)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (4.81e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (2.87e-4)" "prognostic favorable (1.66e-4)" "prognostic unfavorable (2.80e-8)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (6.71e-2)" "unprognostic (3.88e-2)" 96.5 12.1 4.2 8.3 4.5 2.1 80.4 6.5 5.8 147.1 27.8 23.5 37.1 46.4 20.6 62.8 67.7 14.9 34.8 6.5 2.7 41.5 237.3 15.0 2.4 4.4 3.1 47.0 16.8 6.4 14.8 30.3 5.0 44.0 14.4 4.1 33.9 24.6 9.5 60.0 32.3 41.1 1.9 6.9 28.2 9.1 3.9 4.7 37.6 5.7 5.6 41.6 99.6 4.4 3.7 168.0 19.1 18.4 282.5 36.1 34.6 5.9 32.2 12.6 12.0 22.2 48.0 0.3 32.7 21.1 53.7 68.6 10.9 42.7 3.9 35.7 5.9 8.3 43.5 63.1 53.6 3.0 11.9 37.3 46.0 22.5 18.2 24.0 15.7 6.4 19.9 1.4 11.7 81.9 0.5 6.5 24.5 188.9 7.4 5.9 18.3 28.7 29.7 29.7 16.8 28.5 32.7 25.7 15.4 15.8 34.5 2.7 4.9 35.4 28.2 86.8 14.2 1.1 0.6 1.4 16.6 8.9 6.4 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 4.2 4.5 6.5 5.8 6.5 2.7 4.4 3.1 5.0 1.9 3.9 4.4 6.2 0.0 0.5 1.0 0.5 17.3 12.1 25.8 27.9 3.5 13.6 13.2 3.2 11.5 12.1 1.8 0.0 50.0 0.1 33.2 0.0 6.7 0.2 8.1 35.6 5.8 7.8 13.5 0.5 21.7 71.8 33.0 14.8 10.6 1.3 38.7 9.7 506.3 9.9 0.0 0.1 12.4 26.4 9.1 6.4 2.0 37.3 0.8 5.4 1.9 1.6 9.2 0.0 0.0 0.0 21.3 21.2 45.1 0.1 14.6 28.6 21.9 3.0 0.6 0.0 1.0 11.3 0.4 2.0 22.3 22.6 43.8 1.6 8.6 13.8 20.1 TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 83.5" "Group enriched" "Detected in many" 6 "Adipocytes: 72.2;Cardiomyocytes: 22.3;Early spermatids: 29.7;Endothelial cells: 51.8;Hepatic stellate cells: 70.3;Proximal tubular cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 36.7;CAPAN-2: 61.5;GAMG: 35.2;HDLM-2: 48.7;NTERA-2: 33.0;RH-30: 38.4;SCLC-21H: 31.9;SH-SY5Y: 36.2;SuSa: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (8.53e-3)" "unprognostic (3.48e-2)" "unprognostic (6.30e-2)" "unprognostic (8.64e-2)" "unprognostic (7.17e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (6.78e-3)" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-2)" 22.2 46.1 5.8 10.4 4.3 1.2 10.0 30.5 8.2 14.4 3.6 47.9 6.7 46.7 3.6 21.0 20.8 13.3 83.5 26.1 4.6 14.5 4.9 22.4 7.7 5.1 10.4 7.4 1.6 3.9 5.4 30.2 4.9 15.8 9.9 1.0 3.3 41.4 14.7 6.3 16.4 46.6 8.9 14.1 16.6 4.0 10.8 4.0 14.8 19.9 4.2 23.1 10.2 2.3 0.0 0.6 36.7 0.5 0.0 0.0 0.0 0.6 0.5 2.3 0.1 7.3 61.5 0.0 16.4 1.0 35.2 0.0 6.6 0.2 0.6 48.7 2.4 0.2 5.0 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.0 0.0 14.3 0.2 1.1 0.0 0.1 0.0 0.0 0.1 33.0 0.1 1.0 0.1 38.4 0.2 0.0 0.0 31.9 36.2 0.4 0.1 0.1 99.8 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 1.6 1.0 0.0 0.0 1.6 0.1 0.0 0.8 0.2 1.1 0.5 0.0 0.0 1.3 0.2 0.3 0.5 0.0 0.0 0.3 1.7 5.8 4.3 30.5 8.2 26.1 4.6 5.1 10.4 4.9 8.9 10.8 2.3 72.2 0.0 3.7 5.5 1.5 1.7 0.1 0.0 0.6 1.8 1.0 0.3 22.3 0.0 0.0 7.3 0.0 0.1 1.1 0.0 0.0 0.4 29.7 0.7 0.9 51.8 0.0 3.6 2.7 0.2 0.2 6.8 0.5 1.4 1.3 0.0 70.3 1.0 0.4 1.7 4.1 0.0 0.0 2.5 2.6 5.6 2.8 3.4 7.2 2.8 0.2 0.1 0.0 4.0 1.3 0.7 0.0 1.5 0.6 0.2 0.0 20.2 0.0 0.5 0.0 4.9 2.0 0.6 1.0 0.0 1.1 0.3 3.0 3.2 0.0 0.1 TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 705.9;Muller glia cells: 508.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 481.0;naive B-cell: 488.1;plasmacytoid DC: 313.2" "Group enriched" "Detected in all" 5 "B-cells: 488.1;dendritic cells: 313.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" 333.8 143.9 257.2 87.3 248.9 33.3 143.3 253.4 292.4 138.2 288.7 364.2 342.1 130.9 432.8 78.4 249.8 186.2 108.8 247.8 296.3 211.3 87.4 202.1 88.0 250.0 267.7 148.1 140.2 283.4 189.7 111.6 260.2 96.2 386.3 418.6 152.2 187.3 429.1 78.3 349.2 128.3 266.7 84.8 221.2 84.8 282.5 71.6 200.3 374.4 106.9 170.1 67.4 281.3 130.6 347.6 282.8 179.3 484.7 295.8 93.3 203.7 220.2 245.1 265.7 213.5 264.7 126.9 294.8 211.6 234.0 289.0 271.2 139.5 182.9 143.4 410.4 91.0 252.5 204.4 234.5 118.4 64.3 280.9 165.5 135.8 120.1 372.6 304.8 83.1 98.0 109.2 243.3 49.5 105.7 112.1 200.5 414.7 152.4 130.8 351.0 135.3 408.0 73.0 255.0 282.1 139.8 116.9 393.7 269.3 125.0 220.8 292.1 225.7 88.4 138.0 290.7 237.4 346.6 67.1 200.1 173.5 131.9 8.8 51.3 10.4 32.6 69.6 34.1 481.0 16.5 23.9 99.2 488.1 42.6 39.3 4.8 60.3 77.1 313.2 4.6 95.2 257.2 248.9 253.4 292.4 247.8 296.3 250.0 267.7 260.2 266.7 282.5 281.3 76.1 112.2 213.4 69.5 83.8 34.7 77.5 114.6 36.5 247.7 43.6 32.3 98.2 108.7 169.0 68.0 183.5 89.9 41.3 705.9 25.4 250.2 28.5 86.1 63.4 57.6 91.3 19.4 47.8 354.0 35.6 90.8 85.1 41.7 23.4 88.6 53.6 29.5 65.4 127.9 54.3 290.4 97.6 58.0 27.5 57.9 64.3 38.2 72.9 29.0 35.1 508.9 36.0 116.6 32.7 245.1 410.7 51.6 81.2 220.1 364.3 65.5 201.7 185.1 26.3 44.8 189.0 108.0 64.6 34.2 34.2 75.9 19.4 149.5 205.2 381.4 TSPAN32 "PHEMX, TSSC6" ENSG00000064201 "Tetraspanin 32" Q96QS1 11 2301997-2318204 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 19.9;heart muscle: 11.4;lymphoid tissue: 5.5" "Cell type enhanced" "Detected in some" "dendritic cells: 44.6;Erythroid cells: 20.6;granulocytes: 30.4;Langerhans cells: 19.6;NK-cells: 87.6;T-cells: 21.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "HEL: 15.0;HL-60: 6.6;NB-4: 5.3;THP-1: 5.6;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA024135 Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA024135: AB_1858409" "unprognostic (7.50e-3)" "unprognostic (4.88e-4)" "unprognostic (1.58e-2)" "unprognostic (1.74e-1)" "unprognostic (4.45e-3)" "unprognostic (2.10e-4)" "unprognostic (7.72e-3)" "unprognostic (8.25e-3)" "unprognostic (9.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.28e-7)" "unprognostic (1.07e-1)" "unprognostic (4.20e-1)" "unprognostic (4.35e-1)" "unprognostic (8.13e-2)" 0.5 0.5 0.2 1.6 0.2 19.9 0.3 0.5 0.2 1.1 0.0 0.5 0.3 0.7 0.2 0.4 0.5 1.4 11.4 0.2 0.3 0.2 0.4 2.0 5.5 0.5 0.3 0.5 0.0 0.0 0.0 0.3 0.3 0.2 0.3 0.2 0.9 0.5 0.3 0.6 0.5 0.0 0.1 3.5 0.9 0.2 0.2 0.9 0.2 0.2 2.4 0.7 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 15.0 0.0 0.1 0.6 6.6 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 8.9 0.0 40.5 31.8 4.2 25.8 40.9 16.5 2.4 9.1 22.7 32.2 1.1 7.2 27.1 17.3 58.6 46.0 1.6 13.2 21.7 0.2 0.2 0.5 0.2 0.2 0.3 0.5 0.3 0.3 0.1 0.2 0.5 0.5 0.0 6.7 0.0 4.5 0.9 0.0 0.0 0.0 0.0 0.2 0.1 15.9 0.0 0.6 0.0 0.0 0.1 44.6 0.0 0.0 0.0 0.8 0.1 0.3 0.8 0.0 20.6 0.0 0.0 0.3 1.3 0.5 0.0 30.4 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 6.5 19.6 4.1 0.9 13.6 1.8 1.0 14.4 0.2 87.6 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.2 1.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 21.9 0.0 0.0 0.1 TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 542.1" "Cell type enhanced" "Detected in many" "Astrocytes: 274.9;Excitatory neurons: 215.6;Hepatic stellate cells: 407.3;Inhibitory neurons: 249.8;Oligodendrocyte precursor cells: 353.4" "Cancer enhanced" "Detected in all" "glioma: 71.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 109.5;JURKAT: 380.9;MOLT-4: 239.7;SCLC-21H: 129.0;U-266/70: 163.2" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB062566: AB_2665608, CAB068245: AB_2665609, HPA003140: AB_1078454" "unprognostic (1.12e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.06e-2)" "unprognostic (3.90e-3)" "unprognostic (3.88e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.54e-1)" "prognostic favorable (5.48e-7)" "unprognostic (5.65e-3)" "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" 56.1 125.6 355.5 17.2 433.8 1.3 33.5 369.5 542.1 42.6 271.3 68.1 36.3 43.8 37.6 33.6 36.5 25.8 70.3 413.7 334.3 56.2 45.0 67.4 41.1 290.3 298.8 19.6 19.8 13.9 28.0 25.1 283.6 18.8 64.6 286.9 12.5 26.8 153.9 19.4 34.0 51.1 291.7 96.3 14.5 4.8 331.7 15.7 51.3 232.3 28.9 29.7 16.9 384.6 0.1 0.0 2.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 3.8 1.6 0.0 109.5 14.9 0.5 0.0 67.2 0.0 0.1 1.2 1.5 0.0 0.0 0.0 0.0 0.0 380.9 0.0 0.4 1.7 0.4 239.7 0.0 11.2 0.1 0.0 14.6 4.6 0.0 11.0 1.4 129.0 14.4 0.0 0.0 4.3 6.5 0.0 0.3 0.0 0.1 3.1 0.1 1.0 163.2 54.8 0.0 5.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 355.5 433.8 369.5 542.1 413.7 334.3 290.3 298.8 283.6 291.7 331.7 384.6 116.1 12.8 23.8 274.9 1.1 10.6 2.7 6.3 6.2 92.0 1.0 3.8 34.1 1.5 4.6 11.0 43.8 0.4 0.2 69.1 23.5 0.4 0.0 2.1 1.6 153.3 18.7 5.3 215.6 0.6 0.4 14.0 4.6 5.6 10.1 108.1 407.3 4.8 45.1 97.6 249.8 23.5 0.0 15.0 10.0 1.9 0.6 1.5 14.2 46.9 0.0 102.3 0.0 353.4 50.6 0.9 21.9 3.0 1.5 2.4 40.3 9.8 1.2 107.4 59.2 26.5 11.7 0.6 3.3 9.9 6.5 0.8 2.6 27.0 35.7 0.9 TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS" ENSG00000100300 "Translocator protein" "B1AH88, P30536" 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 690.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1429.2;Pancreatic endocrine cells: 1442.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 516.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (5.29e-3)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (4.02e-3)" "unprognostic (3.95e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.34e-3)" 249.3 164.5 42.3 65.3 46.3 488.7 204.3 50.9 61.1 217.3 45.8 189.7 73.6 91.8 8.7 690.1 108.5 39.4 174.7 39.9 51.0 120.5 81.9 181.5 44.3 61.9 48.8 72.3 93.4 22.4 50.8 30.5 57.4 126.6 33.9 4.2 244.9 28.9 84.0 388.0 116.9 26.6 58.0 206.9 216.9 21.4 59.5 22.2 77.4 27.5 39.9 135.7 355.5 69.0 300.0 143.3 10.2 134.4 54.7 175.3 10.8 216.6 107.0 109.4 115.7 28.8 222.4 0.3 147.8 175.7 52.2 242.2 27.9 171.7 13.9 49.5 111.4 28.9 150.4 10.1 193.4 66.4 145.0 137.5 276.4 65.9 58.2 125.8 262.9 0.2 24.0 53.6 114.2 244.5 1.1 188.5 11.6 154.0 355.7 67.0 0.0 516.2 139.3 173.8 14.0 65.4 103.9 200.4 263.5 0.1 76.3 256.6 269.7 132.6 96.9 135.5 92.9 21.7 4.1 2.7 170.0 218.3 171.4 656.8 1678.5 931.0 314.7 1051.6 247.7 199.2 429.9 309.2 1170.2 266.9 325.9 264.3 1052.3 365.0 713.1 209.0 539.5 1585.6 42.3 46.3 50.9 61.1 39.9 51.0 61.9 48.8 57.4 58.0 59.5 69.0 225.5 160.3 140.0 3.6 88.9 366.8 392.3 1429.2 554.3 2.8 269.3 360.2 92.1 323.1 555.7 206.0 2.1 10.0 140.3 680.7 369.8 578.5 2.4 170.8 143.6 220.4 194.9 239.9 0.3 586.4 284.9 205.1 440.9 309.5 268.6 124.3 187.1 110.5 758.5 3.3 0.8 636.8 478.1 644.7 524.7 11.7 82.6 611.6 723.9 10.3 776.9 180.5 207.0 6.0 20.1 1442.1 705.9 157.6 76.3 526.2 471.9 180.7 283.2 19.4 105.2 108.2 197.8 2.8 4.5 1067.4 536.0 20.0 180.0 30.5 664.1 786.1 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TTC16 FLJ32780 ENSG00000167094 "Tetratricopeptide repeat domain 16" Q8NEE8 9 127716079-127731590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "fallopian tube: 6.9;testis: 16.0" "Group enriched" "Detected in some" 4 "Early spermatids: 103.1;Late spermatids: 258.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.10e-3)" "unprognostic (1.63e-3)" "unprognostic (3.86e-3)" "unprognostic (2.02e-4)" "unprognostic (4.08e-3)" "unprognostic (2.25e-3)" "unprognostic (8.87e-4)" "unprognostic (2.91e-2)" "unprognostic (2.25e-2)" "unprognostic (2.36e-1)" "unprognostic (1.96e-3)" "unprognostic (7.32e-2)" "unprognostic (9.14e-3)" "unprognostic (6.35e-3)" "unprognostic (5.29e-2)" "unprognostic (1.17e-1)" "unprognostic (5.54e-3)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.2 0.0 6.9 0.1 0.0 0.1 0.1 0.1 0.0 0.7 0.4 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 16.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 1.0 0.0 0.5 1.1 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.6 0.2 0.2 0.1 0.1 0.1 0.0 0.6 0.0 0.4 0.1 0.1 1.0 0.0 0.0 0.2 0.1 0.8 1.5 5.7 0.0 0.0 0.0 13.7 0.0 0.0 0.0 103.1 6.0 0.1 0.5 1.2 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.3 0.0 258.3 1.2 0.3 1.8 0.0 0.3 0.2 9.2 4.5 0.1 0.0 0.0 3.8 2.6 0.0 0.0 0.4 41.8 0.5 0.0 0.1 0.4 17.9 1.6 0.0 0.0 0.0 7.4 3.8 0.0 0.1 TTC24 ENSG00000187862 "Tetratricopeptide repeat domain 24" A2A3L6 1 156579723-156587719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 21.2" "Group enriched" "Detected in some" 5 "B-cells: 4.6;dendritic cells: 3.6;Erythroid cells: 1.3;NK-cells: 2.1;Skeletal myocytes: 1.7;T-cells: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NK-cell: 3.7;plasmacytoid DC: 12.4" "Group enriched" "Detected in many" 4 "dendritic cells: 12.4;NK-cells: 3.7" "Cell line enhanced" "Detected in some" "JURKAT: 10.3;MOLT-4: 3.8;REH: 11.9;U-698: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029799 Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA029799: AB_10601684" "unprognostic (2.43e-3)" "unprognostic (5.61e-5)" "unprognostic (5.86e-2)" "unprognostic (1.39e-1)" "unprognostic (2.62e-1)" "unprognostic (4.48e-6)" "unprognostic (6.26e-2)" "unprognostic (1.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (4.42e-1)" "unprognostic (7.96e-2)" "unprognostic (4.87e-9)" "unprognostic (1.07e-2)" "unprognostic (5.19e-2)" "unprognostic (2.22e-2)" "unprognostic (9.76e-4)" 0.1 0.0 0.0 1.9 0.1 1.8 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 5.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.2 0.2 0.0 0.0 3.0 0.4 0.1 0.0 21.2 0.1 0.0 5.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.1 0.0 3.8 0.7 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 1.1 0.1 1.7 0.2 1.8 0.2 3.7 0.0 12.4 0.0 0.4 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 TTC38 FLJ20699 ENSG00000075234 "Tetratricopeptide repeat domain 38" Q5R3I4 22 46267961-46294008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 233.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 134.2;NK-cells: 182.3;Proximal enterocytes: 144.5;Proximal tubular cells: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 90.5" "Group enriched" "Detected in all" 4 "granulocytes: 29.9;NK-cells: 38.0;T-cells: 90.5" "Cell line enhanced" "Detected in many" "Hep G2: 76.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029302, HPA075893" Approved Approved Cytosol NA NA 170000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA029302: AB_10601704, HPA075893: " "unprognostic (7.78e-2)" "unprognostic (5.85e-2)" "unprognostic (4.92e-3)" "prognostic favorable (3.21e-6)" "unprognostic (8.34e-2)" "unprognostic (6.38e-2)" "unprognostic (8.72e-2)" "unprognostic (3.62e-2)" "unprognostic (9.45e-2)" "unprognostic (7.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.66e-2)" "unprognostic (7.34e-3)" "unprognostic (9.02e-2)" "unprognostic (4.12e-1)" "unprognostic (4.97e-1)" "unprognostic (8.33e-2)" 24.7 23.6 9.5 10.2 11.6 46.9 25.7 10.3 10.7 16.8 12.8 42.1 79.4 13.8 6.4 12.5 17.2 15.5 23.2 9.7 11.0 64.4 233.6 15.6 10.7 13.3 12.3 26.0 35.5 7.6 13.2 7.8 11.9 23.6 31.9 4.7 27.0 7.3 20.6 12.2 80.9 10.3 10.3 22.8 29.1 6.8 12.2 2.5 15.2 12.3 5.9 16.9 13.5 11.3 12.0 13.2 16.4 34.5 15.2 13.1 15.7 17.2 11.5 18.7 14.6 21.8 8.5 0.1 10.8 17.9 7.4 10.8 16.8 13.9 6.8 27.0 36.9 15.6 28.4 76.0 21.0 9.0 59.8 22.6 7.3 8.5 9.7 12.9 15.9 0.2 11.9 19.4 12.2 12.1 0.3 28.2 12.5 22.6 13.1 0.0 8.0 8.0 12.6 13.8 2.9 22.8 23.7 16.3 13.3 7.5 26.1 18.0 18.5 13.0 14.1 10.3 11.0 14.7 9.2 1.7 8.8 13.7 13.8 29.9 11.9 22.5 90.5 11.4 9.7 2.3 8.5 41.0 10.8 1.7 3.5 36.9 7.6 38.0 8.7 4.3 4.5 42.5 9.5 11.6 10.3 10.7 9.7 11.0 13.3 12.3 11.9 10.3 12.2 11.3 9.2 0.0 7.5 13.7 6.5 3.3 5.9 4.3 3.4 2.6 10.2 6.7 9.2 38.6 4.3 9.2 6.2 10.4 69.1 69.0 23.5 10.4 0.3 7.4 9.6 8.9 20.9 10.5 0.3 10.2 9.3 7.5 11.7 6.9 17.2 13.3 9.7 134.2 13.4 5.0 1.8 37.8 4.1 14.9 4.3 0.9 7.5 9.6 5.4 9.4 12.8 9.3 182.3 5.5 5.6 9.7 51.6 13.9 16.2 8.6 144.5 149.6 5.3 5.4 6.6 7.4 5.9 1.8 3.7 5.3 8.2 6.4 29.2 22.7 51.7 4.6 TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 59.5" "Group enriched" "Detected in many" 9 "Early spermatids: 425.0;Late spermatids: 616.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 31.7" "Lineage enriched" "Detected in single" 42 "dendritic cells: 31.7" "Cell line enhanced" "Detected in many" "HDLM-2: 70.6;MCF7: 52.4;SK-BR-3: 153.7;T-47d: 111.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 2.2 8.2 3.5 3.3 3.5 1.7 35.9 3.0 9.6 14.1 0.0 29.5 6.1 1.0 15.9 18.4 7.5 14.9 15.3 1.0 11.4 26.6 2.8 9.1 1.4 7.4 5.3 0.3 13.5 13.5 11.0 0.3 14.0 20.5 35.2 4.6 11.5 4.2 4.1 10.5 8.1 1.6 2.2 0.3 29.4 59.5 7.7 0.5 10.1 1.7 2.0 8.0 9.4 3.7 6.4 3.4 0.7 0.3 0.4 0.7 28.2 0.3 0.2 0.2 0.2 18.2 2.8 0.1 9.6 0.4 0.4 0.2 3.8 0.2 0.1 70.6 9.7 0.5 1.8 3.2 1.1 0.0 0.7 0.1 1.6 0.1 0.0 0.8 1.4 0.2 0.4 0.1 0.2 52.4 0.6 0.2 4.8 33.8 0.6 0.1 0.2 4.3 28.6 9.1 22.1 1.6 0.5 153.7 1.8 2.0 111.7 0.8 0.8 0.4 2.5 0.5 0.5 5.4 7.1 0.2 2.1 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 31.7 0.0 0.3 3.5 3.5 3.0 9.6 1.0 11.4 7.4 5.3 14.0 2.2 7.7 3.7 0.4 3.2 25.2 1.3 1.1 1.5 5.3 1.7 0.0 2.5 30.8 15.1 13.0 5.7 6.4 9.2 0.0 0.5 15.3 29.3 11.7 38.9 425.0 5.4 3.0 1.9 41.4 9.7 9.7 52.7 4.8 0.9 21.9 9.5 3.8 0.5 0.4 0.6 2.0 0.0 10.2 56.0 6.1 0.3 1.3 616.8 2.5 0.9 0.0 1.0 2.6 1.7 0.0 0.0 0.9 30.5 13.7 2.6 0.4 12.0 2.7 24.4 9.3 7.3 6.6 1.8 1.3 22.8 6.5 4.8 6.5 3.4 1.7 0.5 20.7 14.6 TTC6 "C14orf25, NCRNA00291" ENSG00000139865 "Tetratricopeptide repeat domain 6" Q86TZ1 14 37595847-38041442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 7.9;prostate: 17.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 13.8;Club cells: 11.1;Early spermatids: 39.1;Late spermatids: 18.1;Spermatocytes: 10.7" "Group enriched" "Detected in some" 7 "breast cancer: 2.2;prostate cancer: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 8.4;MCF7: 12.2;RT4: 8.4;T-47d: 22.8" "Not detected" "Not detected" "Region enriched" "Detected in some" 7 "midbrain: 9.7" HPA069293 Approved Centrosome NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Centrosome "HPA069293: AB_2686110" "unprognostic (7.92e-2)" "unprognostic (6.95e-2)" "unprognostic (9.22e-2)" "unprognostic (1.98e-1)" "unprognostic (7.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.68e-1)" "unprognostic (3.60e-4)" "unprognostic (6.75e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-4)" "unprognostic (5.60e-2)" "unprognostic (8.91e-8)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-1)" "unprognostic (6.07e-3)" 0.0 0.0 0.5 0.2 0.8 0.0 7.9 0.1 0.8 0.1 1.1 1.0 0.6 0.0 0.0 0.4 0.3 0.7 0.0 0.7 1.0 0.0 3.5 1.1 0.0 2.5 5.0 0.0 0.0 0.0 0.3 0.0 1.3 17.5 0.5 0.0 2.7 0.1 0.0 0.7 0.7 0.0 3.9 0.0 3.6 5.8 3.9 0.0 0.0 0.0 0.1 1.4 0.3 1.0 0.7 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.0 0.4 0.0 0.0 2.4 1.3 0.2 0.0 0.0 3.4 0.0 1.2 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 12.2 0.0 0.0 0.0 1.7 4.5 0.0 0.0 0.0 1.0 8.4 2.4 0.0 0.0 4.5 0.0 0.0 22.8 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.8 0.7 1.0 2.5 5.0 1.3 3.9 3.9 1.0 0.2 0.0 8.4 0.3 0.1 0.0 2.8 1.5 6.2 0.0 13.8 6.9 0.8 1.5 11.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 39.1 0.0 0.0 0.4 7.7 0.0 6.4 0.0 0.0 0.4 7.1 0.1 0.0 0.0 0.0 2.5 0.0 0.0 1.0 0.7 0.0 0.0 0.0 18.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.8 0.4 0.0 4.9 0.0 0.0 7.5 0.0 0.0 0.2 0.4 10.7 1.9 2.3 0.0 0.0 0.3 0.0 1.1 3.1 TTLL10 "FLJ36119, TTLL5" ENSG00000162571 "Tubulin tyrosine ligase like 10" Q6ZVT0 1 1173880-1197936 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 13.1;fallopian tube: 10.7;testis: 41.9" "Group enriched" "Detected in many" 6 "Early spermatids: 244.1;Late spermatids: 768.4" "Cancer enhanced" "Detected in some" "cervical cancer: 1.5;endometrial cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 32 "SCLC-21H: 38.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA042712 Uncertain NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" "HPA042712: AB_10797019" "unprognostic (1.74e-1)" "unprognostic (7.95e-2)" "unprognostic (2.66e-3)" "prognostic favorable (1.61e-5)" "unprognostic (5.33e-2)" "unprognostic (2.68e-3)" "unprognostic (4.93e-3)" "unprognostic (2.14e-3)" "unprognostic (4.50e-1)" "unprognostic (3.69e-2)" "unprognostic (1.28e-2)" "unprognostic (6.63e-2)" "unprognostic (6.00e-4)" "unprognostic (8.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.12e-1)" "unprognostic (4.39e-2)" 1.3 0.0 0.6 0.1 0.4 0.0 1.1 0.2 0.4 1.7 13.1 0.2 0.1 0.2 0.4 0.3 10.7 0.3 0.2 0.8 0.9 0.4 0.0 2.8 0.1 2.6 3.7 0.0 0.3 0.0 2.1 1.5 1.8 0.3 0.1 0.0 0.3 0.1 0.4 0.2 0.2 0.0 2.0 0.1 0.5 41.9 0.9 0.0 0.2 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 38.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.4 0.8 0.9 2.6 3.7 1.8 2.0 0.9 0.6 14.4 0.0 0.5 0.0 0.3 1.8 0.7 3.0 0.0 0.1 1.4 1.0 0.8 1.5 3.4 0.0 2.1 0.0 0.9 0.9 0.0 0.5 244.1 52.2 0.6 2.1 0.0 0.0 0.2 1.3 1.0 0.3 3.6 6.5 0.0 0.0 0.4 0.0 0.0 0.0 0.1 3.1 0.0 0.0 1.1 768.4 5.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.5 1.0 4.5 0.0 1.5 0.4 0.1 72.5 0.1 6.6 0.9 1.0 9.3 2.1 1.0 2.0 0.1 0.9 0.0 3.6 1.3 TTLL9 "C20orf125, dJ310O13.1" ENSG00000131044 "Tubulin tyrosine ligase like 9" Q3SXZ7 20 31870702-31944963 "Cancer-related genes, Predicted intracellular proteins" Ligase "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.4;choroid plexus: 10.3;epididymis: 2.6;fallopian tube: 6.2;testis: 5.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 20.8;Early spermatids: 39.3;Endometrial ciliated cells: 25.8;Late spermatids: 69.8;Oligodendrocytes: 28.0;Respiratory ciliated cells: 50.2" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041772, HPA055676" Uncertain Uncertain Nucleoplasm,Microtubules NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Microtubules" "HPA041772: AB_10959904, HPA055676: AB_2682881" "unprognostic (8.77e-2)" "unprognostic (8.19e-3)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (4.63e-1)" "unprognostic (1.53e-3)" "unprognostic (1.80e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.59e-1)" "unprognostic (9.05e-3)" "unprognostic (6.17e-2)" "unprognostic (8.35e-3)" "unprognostic (1.84e-1)" "unprognostic (1.70e-1)" "unprognostic (1.25e-3)" "unprognostic (2.23e-2)" 0.1 0.1 2.0 0.0 2.1 0.0 0.2 2.2 2.2 0.9 10.3 0.0 0.0 0.1 2.6 0.0 6.2 0.1 0.0 2.5 2.3 0.7 0.0 1.1 0.1 3.8 4.4 0.1 0.2 0.6 0.9 0.0 3.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 3.0 0.2 0.0 5.0 2.4 0.0 0.6 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.1 2.2 2.2 2.5 2.3 3.8 4.4 3.0 3.0 2.4 2.6 0.2 12.8 20.8 13.1 0.1 0.1 1.1 1.1 0.0 1.8 0.4 0.6 0.9 0.0 8.1 0.0 4.2 0.1 0.1 0.0 0.0 0.2 39.3 25.8 0.7 1.1 0.0 0.0 5.6 0.0 0.0 1.6 0.0 0.8 7.6 0.8 0.4 0.1 0.0 5.0 7.8 0.2 2.0 0.6 0.5 69.8 1.5 3.5 0.0 1.0 0.8 0.4 0.0 15.1 28.0 0.1 0.0 1.2 0.0 0.5 0.0 0.2 50.2 0.8 0.0 0.8 0.7 13.8 1.2 0.0 0.1 0.0 2.7 0.4 0.0 0.4 TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 364.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 516.5;Suprabasal keratinocytes: 368.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cell line enhanced" "Detected in all" "AF22: 241.1;CACO-2: 247.6;SuSa: 365.5;WM-115: 280.1" "Low region specificity" "Detected in all" "CAB015339, HPA043640, HPA046280" Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB015339: AB_2210539, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.57e-1)" "unprognostic (9.86e-3)" "unprognostic (5.90e-3)" "unprognostic (7.98e-3)" "unprognostic (4.02e-3)" "unprognostic (1.67e-1)" "unprognostic (1.82e-3)" "unprognostic (7.53e-2)" "unprognostic (1.48e-3)" "unprognostic (9.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.42e-2)" "prognostic favorable (4.65e-4)" "unprognostic (2.39e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (1.61e-4)" 58.8 17.8 266.1 19.3 251.1 67.5 47.8 130.1 287.5 32.7 10.0 78.0 24.2 50.8 28.0 90.6 23.5 21.5 29.4 248.3 364.3 31.1 67.0 16.4 11.0 292.6 212.2 15.5 39.4 2.2 56.3 23.9 334.3 17.5 8.2 49.9 52.2 15.6 22.3 151.4 34.9 41.7 131.6 7.7 41.0 9.5 204.4 6.4 10.0 11.8 9.6 23.6 51.2 169.4 55.9 45.3 241.1 53.6 30.6 34.0 14.5 119.8 44.7 80.6 115.7 247.6 18.4 27.4 72.9 115.5 80.2 26.0 86.6 26.8 28.0 134.1 57.7 9.4 11.4 77.0 31.6 1.5 8.4 35.1 31.1 85.1 5.3 28.9 37.3 10.6 33.7 8.8 74.2 25.1 14.9 2.8 207.2 16.0 58.3 12.4 22.6 18.9 28.0 27.4 57.6 52.9 30.5 8.5 179.7 365.5 19.1 2.0 76.0 53.9 56.7 117.3 65.8 3.2 4.6 18.8 19.7 7.0 280.1 0.0 1.1 0.0 2.2 1.6 2.4 3.2 2.1 3.1 0.5 0.6 1.0 2.0 0.3 0.4 1.3 0.2 3.2 1.2 266.1 251.1 130.1 287.5 248.3 364.3 292.6 212.2 334.3 131.6 204.4 169.4 125.3 16.0 13.1 43.1 31.6 311.4 63.3 87.0 132.6 105.6 32.0 134.6 20.4 42.9 62.7 12.9 16.7 6.0 53.4 87.0 217.2 54.0 60.9 46.7 29.6 40.6 73.1 322.3 59.9 182.4 50.4 96.2 185.0 57.9 34.9 10.1 12.5 55.6 50.8 516.5 73.0 103.9 73.2 6.3 164.4 32.9 20.8 36.7 129.9 24.4 72.7 261.0 0.0 18.1 23.0 103.4 181.8 15.4 15.8 34.9 126.3 40.4 50.3 86.2 6.6 95.6 87.9 32.4 14.9 140.6 368.5 6.2 58.9 6.4 60.0 54.7 TUBB4B "Beta2, TUBB2C" ENSG00000188229 "Tubulin beta 4B class IVb" P68371 9 137241287-137243707 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, FDA approved drug targets, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2190.0;Late spermatids: 2907.1;Spermatocytes: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010880, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010880: AB_609915, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.24e-1)" "unprognostic (1.77e-3)" "unprognostic (1.50e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (9.98e-4)" "unprognostic (9.92e-3)" "unprognostic (2.90e-1)" "unprognostic (3.63e-1)" "unprognostic (2.34e-1)" "unprognostic (4.09e-2)" "unprognostic (2.47e-3)" "unprognostic (6.37e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.36e-6)" "unprognostic (1.69e-1)" 134.5 112.6 162.0 97.2 163.4 423.9 94.4 149.4 182.7 88.1 482.7 198.3 142.0 107.7 209.1 343.3 507.2 106.0 435.8 174.0 185.2 122.5 140.1 130.5 95.5 184.1 233.6 72.9 123.8 87.8 118.0 86.3 213.9 120.2 111.9 261.8 177.9 121.5 202.5 240.0 166.4 119.8 162.9 85.6 161.4 765.7 192.6 162.9 115.7 96.6 119.7 188.3 139.4 133.9 706.2 1032.5 431.7 314.2 213.2 223.6 600.5 643.7 536.0 872.4 598.6 1101.0 840.2 429.0 480.2 631.2 848.2 1305.1 539.5 1039.2 330.2 307.9 458.5 311.2 789.6 877.8 134.5 370.0 331.5 145.0 291.5 667.5 183.1 215.7 631.7 300.6 443.0 239.7 731.2 1936.4 337.4 504.2 457.8 1234.8 1778.1 423.5 822.2 394.2 666.8 647.8 301.5 323.6 853.9 485.8 173.2 244.2 699.0 397.6 495.6 618.1 685.0 710.0 863.6 92.4 274.9 475.1 503.6 286.9 549.8 95.7 30.0 43.2 40.5 30.1 38.2 32.6 31.3 34.4 34.9 30.8 19.7 26.7 56.4 24.4 30.5 36.3 44.7 32.6 162.0 163.4 149.4 182.7 174.0 185.2 184.1 233.6 213.9 162.9 192.6 133.9 478.5 221.2 146.3 21.5 315.8 326.2 945.7 458.7 327.2 508.1 286.9 389.5 91.9 143.0 284.1 143.5 300.3 346.6 640.9 744.1 221.1 348.6 2190.0 1191.6 224.8 203.9 391.5 419.9 30.1 446.8 545.5 247.8 274.7 415.0 189.2 200.9 142.5 139.2 265.9 244.0 24.3 503.6 323.5 59.9 214.9 2907.1 254.2 299.3 138.7 22.5 224.0 299.3 49.4 15.6 19.7 477.4 697.2 153.1 264.0 475.1 540.7 345.5 1558.7 763.3 111.7 261.8 416.0 1717.5 740.9 419.1 297.6 321.1 362.9 89.8 487.3 592.7 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 TUBG1 "TUBG, TUBGCP1" ENSG00000131462 "Tubulin gamma 1" P23258 17 42609641-42615238 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 173.8" "Cell type enhanced" "Detected in all" "Early spermatids: 670.6;Erythroid cells: 286.9;Late spermatids: 560.5;Spermatocytes: 347.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004608 Enhanced NA Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "CAB004608: AB_628417" "unprognostic (1.00e-1)" "unprognostic (5.57e-2)" "unprognostic (1.79e-2)" "prognostic favorable (8.99e-4)" "unprognostic (2.86e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (1.08e-8)" "unprognostic (2.62e-3)" "unprognostic (5.67e-2)" "unprognostic (1.83e-1)" "unprognostic (3.79e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.48e-5)" "unprognostic (2.64e-1)" "unprognostic (3.52e-1)" "unprognostic (2.61e-3)" "unprognostic (1.97e-2)" 23.0 30.4 17.7 20.4 18.4 51.7 19.0 17.8 25.4 17.6 21.1 24.0 16.6 20.7 13.4 35.6 16.3 10.1 43.6 18.5 19.8 24.8 27.1 19.1 18.0 20.3 18.0 12.5 48.7 29.9 20.2 21.0 20.0 19.7 14.9 10.5 19.1 18.3 60.7 29.0 18.1 27.2 15.9 19.3 29.8 173.8 21.4 27.6 14.8 36.3 20.6 21.7 19.9 19.7 117.8 288.8 112.1 124.0 70.5 47.8 97.7 133.4 87.2 205.6 158.8 177.4 76.9 80.2 92.8 105.9 178.5 171.9 124.2 178.0 149.7 225.9 142.6 64.1 168.5 299.3 34.6 73.8 87.6 38.1 54.0 251.1 75.8 50.6 131.9 119.0 119.7 77.2 155.9 326.7 176.3 66.2 59.3 176.7 139.1 81.8 164.2 130.5 91.7 136.6 158.9 74.5 78.0 76.9 63.6 113.9 233.6 70.2 88.5 197.9 131.0 169.2 207.0 111.2 169.0 126.2 108.6 70.6 144.2 1.7 13.1 3.1 10.6 25.1 11.6 14.9 9.8 11.4 15.7 15.0 10.4 10.5 0.4 12.7 27.4 44.1 13.5 10.4 17.7 18.4 17.8 25.4 18.5 19.8 20.3 18.0 20.0 15.9 21.4 19.7 14.9 16.0 4.2 3.9 12.8 17.6 16.3 49.4 12.0 14.1 14.6 16.5 18.8 14.3 24.1 7.3 4.2 45.8 7.0 10.2 39.2 35.2 670.6 15.1 13.7 20.1 9.6 286.9 7.2 54.4 78.6 15.7 15.8 10.7 2.5 16.9 15.7 15.9 40.2 20.2 6.4 13.7 38.7 6.3 10.8 560.5 22.7 9.7 17.8 8.4 26.4 17.7 10.3 4.0 3.8 42.3 6.2 21.8 41.5 15.2 15.1 76.6 18.1 10.9 59.2 7.1 43.5 347.8 128.0 27.3 28.6 20.1 8.5 15.0 14.0 15.6 TXNDC5 "EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15" ENSG00000239264 "Thioredoxin domain containing 5" Q8NBS9 6 7881517-7910788 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 42 "Plasma cells: 677.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "memory B-cell: 13.0;naive B-cell: 6.9;plasmacytoid DC: 26.7" "Group enriched" "Detected in many" 21 "B-cells: 13.0;dendritic cells: 26.7" "Cell line enhanced" "Detected in all" "RPMI-8226: 2833.2;U-266/84: 6053.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034677, HPA034678" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 6900000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA034677: AB_2674275, HPA034678: AB_2674276" "unprognostic (3.15e-1)" "unprognostic (1.09e-2)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" "unprognostic (6.95e-2)" "unprognostic (1.20e-2)" "unprognostic (6.07e-2)" "unprognostic (5.81e-2)" "unprognostic (3.56e-2)" "unprognostic (1.54e-1)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.05e-1)" "unprognostic (7.98e-2)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" 97.4 74.8 21.1 173.0 23.4 61.8 163.4 22.0 22.5 132.2 52.7 266.2 263.5 80.5 85.8 78.2 63.9 98.6 63.3 19.8 23.2 63.1 133.3 90.9 194.2 25.0 24.7 96.4 154.6 68.6 42.5 134.0 23.2 73.2 213.6 4.4 219.3 93.6 25.1 32.9 193.9 121.9 24.9 250.6 287.6 28.3 26.4 54.1 69.6 29.2 263.8 190.9 57.0 25.9 166.1 159.0 111.5 365.9 911.2 388.1 175.9 361.5 349.7 246.2 265.2 238.8 119.0 176.1 620.7 557.2 273.6 127.3 195.5 178.6 280.3 148.8 166.6 267.6 128.3 435.9 268.5 307.2 255.0 266.7 256.8 236.6 259.2 542.1 1334.0 109.7 170.5 1216.5 171.7 147.7 75.2 185.7 142.8 260.5 340.6 128.0 160.4 2833.2 201.1 149.6 168.7 90.5 462.4 280.2 209.4 514.9 143.5 133.9 369.7 280.5 194.2 243.0 386.5 1408.7 6053.9 305.0 144.7 191.7 392.2 0.0 0.4 0.0 0.9 0.7 0.7 13.0 0.2 0.7 1.0 6.9 0.2 0.4 0.0 0.0 0.1 26.7 0.9 0.5 21.1 23.4 22.0 22.5 19.8 23.2 25.0 24.7 23.2 24.9 26.4 25.9 1.3 0.0 4.8 0.0 14.6 0.9 0.2 0.4 3.4 0.0 1.8 1.3 0.2 0.0 2.0 0.0 0.0 0.9 5.6 1.2 0.0 9.0 0.1 1.1 6.9 3.2 4.9 11.2 0.0 10.7 1.9 4.1 6.1 2.3 1.3 0.6 3.9 4.9 1.5 0.0 0.0 15.9 0.0 0.8 0.7 0.0 0.0 1.3 3.6 0.0 1.8 0.1 0.0 0.0 0.0 9.5 1.5 0.4 677.7 0.4 3.2 0.5 1.7 0.5 6.6 0.5 4.2 0.1 0.1 3.9 0.1 1.2 2.0 0.2 5.8 0.2 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;ovary: 49.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.4;Leydig cells: 44.4;Oligodendrocyte precursor cells: 29.1;Oligodendrocytes: 46.8;Peritubular cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 17000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 21.5 3.5 18.2 1.4 30.3 0.8 5.2 17.7 27.1 2.1 0.0 2.3 1.6 4.6 3.5 13.1 11.5 2.5 2.2 27.7 10.7 11.3 0.8 3.3 1.3 20.9 22.6 49.7 9.8 0.9 0.9 5.7 18.6 2.6 0.9 2.6 1.9 6.1 0.9 13.8 2.4 4.4 14.4 5.5 3.2 18.8 15.7 0.4 1.1 1.8 3.7 2.1 4.1 32.0 10.3 6.7 20.7 22.7 18.9 12.8 69.2 14.6 9.3 14.2 13.1 37.7 3.4 0.4 18.3 11.9 19.9 23.7 23.3 3.6 6.5 5.8 15.5 3.2 20.2 18.1 13.3 5.2 0.4 4.1 7.3 10.9 3.6 5.8 10.6 9.8 19.1 4.3 7.9 9.8 2.4 1.0 47.7 16.0 6.7 31.9 18.6 3.8 1.2 19.7 24.6 7.0 13.7 21.6 16.3 29.8 17.8 6.0 8.4 28.0 12.2 21.0 22.5 1.7 3.5 3.1 17.2 33.8 17.2 1.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.2 0.2 1.5 0.3 0.1 0.3 0.1 0.1 18.2 30.3 17.7 27.1 27.7 10.7 20.9 22.6 18.6 14.4 15.7 32.0 3.4 3.2 1.1 17.6 0.9 6.8 8.5 0.4 0.6 2.7 2.2 2.2 2.9 2.8 0.7 3.7 6.2 2.9 1.1 1.3 0.0 3.9 3.6 1.1 13.0 5.4 1.8 0.0 42.4 3.6 10.2 10.5 8.6 1.9 0.0 7.6 9.7 0.4 1.2 0.0 4.6 0.9 0.0 1.9 1.3 5.1 44.4 0.9 8.8 1.0 0.1 8.3 1.0 29.1 46.8 4.6 0.1 47.0 0.3 6.4 1.2 1.2 0.5 4.0 0.0 3.9 4.3 4.0 6.5 4.2 10.9 18.9 0.7 5.8 2.3 5.7 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "dendritic cells: 5.9;Erythroid cells: 3.8;T-cells: 20.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 22.9;memory CD4 T-cell: 28.2;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.2;naive CD8 T-cell: 24.0;T-reg: 27.9" "Lineage enriched" "Detected in many" 12 "T-cells: 32.2" "Group enriched" "Detected in some" 7 "HEL: 23.0;JURKAT: 39.0;MOLT-4: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035367 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "Golgi apparatus" "HPA035367: AB_2732466" "unprognostic (5.14e-4)" "unprognostic (3.91e-4)" "unprognostic (1.57e-2)" "unprognostic (4.10e-5)" "unprognostic (4.33e-2)" "unprognostic (1.85e-6)" "unprognostic (5.54e-4)" "unprognostic (1.46e-3)" "unprognostic (6.17e-4)" "unprognostic (2.47e-3)" "unprognostic (1.94e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-6)" "unprognostic (1.65e-1)" "unprognostic (7.96e-2)" "unprognostic (3.24e-2)" "unprognostic (4.17e-2)" 0.4 0.6 0.0 5.2 0.0 2.5 0.2 0.0 0.1 0.5 0.1 0.8 1.6 0.5 0.0 0.4 0.4 2.0 0.4 0.0 0.1 0.4 0.7 1.7 11.1 0.2 0.0 0.3 0.1 0.0 0.1 0.2 0.1 0.4 0.9 0.0 0.9 0.1 0.2 0.3 2.4 0.1 0.1 4.4 1.9 0.1 0.0 18.9 0.5 0.1 5.1 1.7 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 23.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 39.0 4.4 0.0 0.0 0.0 47.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 12.9 0.0 22.9 0.1 28.2 24.8 0.0 0.0 32.2 24.0 0.5 2.5 0.1 0.1 27.9 10.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.8 0.4 0.0 0.8 0.0 0.0 0.2 0.3 1.0 0.0 0.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.6 0.0 0.3 0.0 3.8 0.0 0.0 0.0 0.4 1.1 0.5 1.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.1 0.6 0.0 0.3 0.0 20.5 0.0 0.0 0.0 UBD FAT10 ENSG00000213886 "Ubiquitin D" O15205 6 29555515-29559732 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 151.3" "Group enriched" "Detected in many" 7 "Ductal cells: 534.8;Exocrine glandular cells: 273.8;monocytes: 151.9;Pancreatic endocrine cells: 510.6" "Cancer enhanced" "Detected in all" "liver cancer: 75.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Hep G2: 63.9;RT4: 52.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043710 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Nucleoli fibrillar center" "HPA043710: AB_2756303" "unprognostic (2.99e-3)" "unprognostic (4.16e-2)" "unprognostic (6.37e-2)" "unprognostic (2.61e-2)" "unprognostic (3.93e-2)" "unprognostic (3.53e-3)" "unprognostic (1.60e-1)" "unprognostic (9.47e-2)" "unprognostic (1.44e-2)" "prognostic favorable (7.35e-4)" "unprognostic (1.28e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (4.04e-2)" "unprognostic (6.02e-2)" "unprognostic (8.40e-2)" "unprognostic (1.21e-2)" 4.2 0.4 0.3 35.6 0.4 0.0 8.6 0.3 0.7 1.7 0.3 13.3 4.2 1.9 1.2 8.3 4.7 0.9 0.6 0.3 0.3 23.2 25.4 10.9 87.5 0.4 0.3 1.2 27.3 1.7 1.4 0.0 0.3 11.9 19.0 0.0 14.6 1.3 0.4 1.8 31.1 1.2 0.3 22.9 27.1 0.8 0.3 90.2 3.0 0.1 151.3 25.8 1.7 0.3 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 63.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 52.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.9 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.7 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.2 3.2 3.1 0.0 0.7 0.1 0.1 2.3 16.5 0.0 1.9 1.9 0.0 21.5 13.3 0.0 0.0 0.0 0.1 6.9 1.9 534.8 0.0 0.3 0.2 7.1 3.6 0.0 0.0 273.8 0.0 2.2 13.3 0.2 0.0 0.0 0.7 0.3 0.1 0.0 0.0 5.2 6.1 0.3 0.0 0.0 0.0 1.2 0.0 0.0 151.9 0.0 0.0 0.0 0.0 510.6 8.3 0.0 0.0 0.5 49.1 1.1 9.7 0.0 0.0 0.0 3.4 0.0 0.0 2.2 0.0 0.0 0.2 0.0 11.1 0.1 UBE2L5 UBE2L5P ENSG00000236444 "Ubiquitin conjugating enzyme E2 L5" A0A1B0GUS4 13 30422488-30429758 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "testis: 46.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045609, HPA062415" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 83: Testis - Spermatogenesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: AB_2684756" "unprognostic (2.09e-1)" "unprognostic (1.18e-2)" "unprognostic (8.01e-3)" "unprognostic (6.41e-4)" "unprognostic (1.78e-1)" "unprognostic (7.13e-2)" "unprognostic (2.20e-1)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-3)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (3.50e-2)" "unprognostic (9.37e-2)" "unprognostic (2.60e-1)" "unprognostic (2.44e-2)" "unprognostic (8.75e-2)" 0.5 0.2 0.2 0.2 0.1 0.3 0.4 0.4 0.4 0.4 0.0 0.3 0.2 0.8 0.2 0.2 0.5 0.1 0.2 0.2 0.0 0.1 0.2 0.2 0.3 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.0 0.4 0.1 0.2 0.2 0.2 0.4 0.7 0.2 0.4 0.0 0.2 0.2 46.5 0.0 0.2 0.2 0.0 0.2 0.3 0.3 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.5 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.2 0.0 0.4 0.2 0.3 0.2 0.7 0.2 0.6 0.2 0.3 0.3 0.4 0.2 0.3 0.4 0.4 0.3 0.3 0.4 0.7 0.2 0.1 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 UFSP1 UFSP ENSG00000176125 "UFM1 specific peptidase 1 (inactive)" Q6NVU6 7 100888721-100889715 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 7.9;Proximal tubular cells: 7.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027099 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027099: AB_2214069" "unprognostic (8.56e-2)" "unprognostic (2.62e-2)" "unprognostic (2.23e-1)" "unprognostic (1.94e-1)" "unprognostic (7.21e-3)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (2.11e-1)" "unprognostic (3.55e-3)" "unprognostic (5.71e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-1)" "unprognostic (2.48e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" 2.0 2.7 1.2 0.9 1.3 0.6 1.6 1.9 1.7 1.5 0.2 1.8 1.0 2.4 1.3 1.9 1.8 0.1 1.6 0.9 1.2 2.1 3.1 1.0 0.6 1.4 1.5 0.9 3.1 1.0 2.3 0.4 1.4 1.8 0.5 0.3 1.7 1.0 3.7 1.1 1.5 0.8 1.2 1.6 1.9 0.7 1.1 0.8 1.4 1.2 0.4 2.1 1.1 1.5 2.9 3.7 0.8 3.8 3.6 2.1 2.3 2.2 0.7 0.9 0.6 1.5 2.0 0.7 1.7 1.8 1.4 5.6 1.1 1.3 0.5 2.6 8.2 2.4 3.2 1.8 3.6 1.0 1.1 2.4 1.6 1.2 4.6 1.0 0.3 1.4 3.7 1.7 1.4 7.3 2.4 6.0 2.8 3.0 5.1 1.2 1.1 5.8 1.6 1.3 2.6 4.3 4.4 5.6 2.7 1.1 1.4 0.9 0.9 2.4 2.5 2.6 1.7 1.7 2.2 0.2 0.8 2.0 2.8 0.0 2.4 1.5 3.1 2.1 3.5 1.0 2.6 1.7 2.9 3.9 2.9 3.6 0.4 3.0 2.2 4.4 1.2 1.7 1.2 1.3 1.9 1.7 0.9 1.2 1.4 1.5 1.4 1.2 1.1 1.5 0.7 0.0 0.0 0.0 0.8 0.6 2.3 1.3 1.8 0.4 1.4 1.3 0.8 1.5 0.7 1.8 0.0 2.4 0.8 2.5 7.9 2.2 0.3 2.2 3.6 0.8 3.0 0.8 0.3 2.1 1.2 1.2 1.1 1.2 0.0 0.6 1.8 4.7 1.9 0.0 0.3 2.2 0.0 0.8 0.7 0.4 1.8 0.6 0.0 1.0 0.5 2.5 0.0 1.0 0.2 1.8 5.0 1.9 1.3 3.2 1.6 7.4 0.7 1.0 6.6 1.5 1.5 0.2 0.3 2.4 1.0 1.6 0.8 4.4 2.5 2.2 UGP2 "SVUGP2, UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840952-63891562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 858.6;tongue: 756.1" "Cell type enhanced" "Detected in all" "Distal enterocytes: 849.9;Hepatocytes: 559.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 417.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria NA NA 13000000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Centrosome, Mitochondria" Nucleoplasm "HPA034696: AB_10670171, HPA034697: AB_2674287, HPA064836: AB_2685365" "unprognostic (1.00e-2)" "unprognostic (6.93e-2)" "unprognostic (5.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.50e-5)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-2)" "unprognostic (8.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (3.93e-2)" "unprognostic (3.81e-1)" "unprognostic (8.44e-2)" 267.3 72.0 79.8 65.8 89.3 40.1 119.7 72.7 109.8 65.9 78.8 177.9 66.0 75.2 50.6 97.5 68.9 60.7 232.5 87.9 81.4 105.4 858.6 65.4 65.7 77.7 77.0 47.0 74.4 113.3 49.8 137.8 77.6 57.4 159.3 36.8 92.9 66.2 498.0 59.1 67.6 78.5 73.2 50.8 69.5 38.3 83.3 106.2 64.5 756.1 73.7 88.4 63.7 91.8 122.3 77.6 63.1 42.0 176.1 222.4 220.6 129.1 116.1 82.7 89.4 170.0 104.5 149.5 48.3 165.6 79.9 57.4 73.4 102.6 137.0 99.2 35.7 86.5 50.4 117.9 87.0 79.1 73.9 148.1 175.8 76.1 80.3 108.4 119.4 38.9 48.2 58.1 327.8 56.7 104.6 75.2 122.9 207.7 50.1 80.4 117.9 84.5 147.4 77.7 36.5 29.6 103.3 149.8 64.3 162.6 51.7 59.2 144.3 84.4 125.9 113.8 90.5 101.3 51.4 174.9 99.2 122.7 225.7 417.1 33.0 53.1 48.0 40.7 51.8 33.0 53.6 50.1 27.9 31.8 57.6 53.6 45.4 70.0 39.5 29.7 127.2 62.0 79.8 89.3 72.7 109.8 87.9 81.4 77.7 77.0 77.6 73.2 83.3 91.8 73.4 28.9 54.0 107.4 65.3 75.8 87.8 245.9 34.7 49.6 360.6 87.1 264.3 104.4 171.6 47.8 64.6 414.3 81.1 849.9 242.6 140.6 91.5 53.0 106.3 69.8 44.5 56.0 86.1 103.6 445.5 159.3 79.0 49.5 67.8 42.4 63.5 559.4 120.9 87.5 78.4 179.8 144.5 102.4 90.2 86.1 79.2 89.1 96.0 62.8 139.7 58.8 154.5 37.2 79.3 91.6 313.9 77.5 60.7 81.2 176.2 284.4 139.3 57.3 72.3 50.5 129.2 84.9 54.9 50.9 57.8 472.8 143.1 90.6 189.5 109.1 ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 28.9;Basal respiratory cells: 17.9;dendritic cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "SiHa: 66.7;U-2197: 47.4" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" 1.5 0.7 1.3 0.6 1.6 1.8 0.7 1.6 2.6 0.9 0.7 0.2 0.2 0.1 0.1 6.1 0.2 0.5 2.0 3.0 1.0 2.1 0.5 3.4 0.3 1.8 1.2 0.0 0.4 0.6 0.5 1.6 1.8 0.2 0.1 0.2 0.7 0.1 0.3 0.5 0.2 0.7 0.8 0.2 0.3 1.5 1.1 0.7 1.2 0.7 0.8 1.4 1.6 1.7 19.9 1.8 0.5 6.1 1.1 5.6 3.3 20.1 11.8 20.6 16.8 7.4 11.0 0.0 29.9 23.0 29.6 13.9 7.6 18.4 11.8 9.1 3.9 1.1 2.8 0.0 7.1 0.0 1.5 2.7 13.9 18.3 8.0 16.7 11.9 16.6 2.5 0.0 15.4 13.9 1.8 0.0 0.0 3.6 10.2 3.0 4.5 0.0 29.0 5.7 0.6 0.0 66.7 1.4 1.9 3.2 1.8 8.5 18.8 13.5 17.1 47.4 23.5 0.0 0.1 0.9 19.2 10.7 9.9 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.8 1.5 0.0 0.0 0.3 1.8 0.0 0.4 0.0 0.0 1.7 0.5 1.3 1.6 1.6 2.6 3.0 1.0 1.8 1.2 1.8 0.8 1.1 1.7 28.9 0.0 1.3 0.0 1.2 3.7 6.5 17.9 7.4 0.0 1.3 4.4 0.3 0.0 9.4 1.8 0.0 0.0 12.1 0.5 0.0 7.5 7.0 0.3 0.5 9.1 0.0 0.0 3.0 8.8 0.5 3.0 1.1 0.2 0.0 0.1 7.1 0.2 2.2 0.0 0.7 0.3 2.0 0.8 2.1 8.0 0.0 3.1 1.8 0.0 0.0 0.4 4.1 0.5 0.3 4.5 0.0 0.0 1.4 1.4 0.0 0.1 1.4 0.0 0.0 1.0 4.2 3.1 7.0 11.8 2.8 0.0 11.0 0.6 0.4 5.2 ULBP3 RAET1N ENSG00000131019 "UL16 binding protein 3" Q9BZM4 6 150061053-150069121 "Predicted intracellular proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.5;testis: 6.3" "Cell type enhanced" "Detected in single" "Gastric mucus-secreting cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA056541, HPA063007" Approved Uncertain "Vesicles,Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Vesicles "Centriolar satellite" "HPA056541: , HPA063007: AB_2684920" "unprognostic (4.87e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (2.99e-2)" "unprognostic (8.47e-2)" "unprognostic (1.96e-1)" "unprognostic (5.87e-2)" "unprognostic (8.71e-2)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (6.26e-2)" "unprognostic (3.43e-1)" "unprognostic (2.12e-1)" "unprognostic (5.45e-2)" "unprognostic (5.16e-2)" 1.3 1.2 1.6 0.7 1.8 0.7 1.0 1.6 2.4 0.5 0.4 0.8 1.1 1.0 0.9 1.5 2.0 1.3 0.7 1.7 1.4 1.7 1.0 1.5 0.5 0.9 0.9 0.8 0.7 0.9 0.1 0.9 0.9 0.7 0.8 0.8 0.4 0.5 6.5 1.1 0.5 0.5 0.2 0.6 1.9 6.3 1.3 0.5 4.9 0.4 0.9 1.0 0.5 1.9 6.2 2.0 6.5 7.3 1.6 11.9 2.3 6.1 2.6 7.2 8.0 11.0 5.1 0.2 11.8 9.9 10.9 8.3 17.7 20.5 7.7 3.7 7.8 0.6 2.9 0.5 2.5 0.1 1.1 10.2 3.5 15.0 8.1 6.9 9.7 0.2 0.5 0.8 6.3 7.0 0.3 0.5 3.1 2.6 14.8 6.2 5.9 0.3 17.5 12.4 1.2 0.5 12.2 8.2 3.0 3.4 2.5 1.7 5.6 1.2 9.8 20.5 13.3 0.3 0.2 4.1 9.6 3.7 5.1 0.8 0.2 0.2 2.2 0.2 2.9 0.8 1.5 2.4 0.2 0.5 0.8 1.2 1.0 0.6 0.2 0.3 2.3 0.4 1.6 1.8 1.6 2.4 1.7 1.4 0.9 0.9 0.9 0.2 1.3 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 ULK3 "DKFZP434C131, FLJ90566" ENSG00000140474 "Unc-51 like kinase 3" Q6PHR2 15 74836118-74843346 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 89.7;Horizontal cells: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040474 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA040474: AB_2677003" "unprognostic (3.67e-2)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (2.07e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-2)" "prognostic favorable (7.47e-4)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-2)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" 7.1 15.2 29.5 6.4 31.5 2.2 6.1 28.1 32.2 13.6 23.0 12.1 5.0 4.4 3.5 35.7 5.5 4.5 15.9 29.4 27.3 17.6 13.8 8.3 5.8 34.0 26.6 5.7 12.0 16.2 12.5 3.5 35.8 9.9 9.4 15.4 11.5 3.1 21.0 24.7 15.7 4.4 26.1 13.1 10.6 7.1 27.8 6.3 7.6 19.0 7.8 9.4 15.4 30.4 6.7 17.7 7.4 14.4 9.3 6.7 6.0 5.1 7.3 10.1 11.1 7.0 15.4 13.0 8.8 6.2 10.8 4.7 23.1 7.6 4.4 26.1 26.1 30.3 25.0 7.4 14.8 10.3 22.5 9.4 14.0 8.2 7.1 3.5 15.8 16.8 10.3 11.9 7.0 9.4 7.3 6.6 10.0 10.6 8.7 18.6 10.3 23.0 6.0 7.4 16.7 22.3 8.6 9.8 25.6 9.1 11.0 26.8 9.4 16.0 8.9 12.7 10.3 20.7 19.7 9.3 7.4 29.5 12.4 5.2 3.5 1.4 10.9 7.3 8.7 3.3 6.4 9.0 3.7 2.8 7.1 4.8 0.8 5.8 6.1 4.0 9.2 5.1 29.5 31.5 28.1 32.2 29.4 27.3 34.0 26.6 35.8 26.1 27.8 30.4 16.5 9.6 15.3 37.2 11.4 10.1 7.5 6.0 10.2 89.7 18.1 13.6 17.1 14.3 6.7 12.9 16.7 9.2 23.3 46.4 19.6 11.0 1.0 8.9 8.8 10.7 11.4 14.1 64.7 11.7 2.5 9.2 23.4 11.9 21.0 6.2 13.2 13.3 16.1 89.2 56.5 17.5 4.1 7.9 8.2 2.2 13.1 11.2 5.4 18.7 13.2 18.4 29.9 16.6 15.3 12.3 17.9 11.7 8.6 10.4 68.5 16.5 8.0 54.5 0.0 12.9 8.8 9.5 17.3 19.7 21.7 5.7 19.7 12.3 27.9 8.9 UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 693 "kidney: 2277.8" "Group enriched" "Detected in some" 146 "Collecting duct cells: 248.3;Distal tubular cells: 950.9" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" NA NA 55000000 66000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2277.8 0.8 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 248.3 0.0 0.0 0.0 0.0 950.9 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108736 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 250.1;Extravillous trophoblasts: 260.3;Macrophages: 199.5;Paneth cells: 260.8" "Cancer enhanced" "Detected in all" "testis cancer: 62.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "hTERT-HME1: 362.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm No No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA054040: AB_2682352, HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" 16.4 9.4 3.8 7.5 4.4 12.5 10.0 3.0 5.8 16.8 2.0 9.8 4.3 3.9 0.8 66.9 5.7 5.9 8.9 3.1 3.9 39.8 11.9 18.8 3.7 4.2 2.8 1.9 4.6 5.0 7.4 3.8 3.7 4.9 5.3 0.5 14.2 1.1 3.7 3.1 6.5 3.4 1.3 20.3 4.1 2.2 4.4 1.2 8.0 0.9 6.6 9.1 31.2 3.7 19.5 26.0 2.4 5.2 8.9 4.0 29.7 7.9 15.5 14.5 17.5 10.8 9.9 0.0 2.5 9.7 89.9 13.9 5.2 46.1 9.4 4.1 4.5 0.8 4.8 4.6 7.4 0.9 1.3 5.0 21.8 6.4 362.8 5.9 9.1 0.4 1.5 13.5 7.6 2.3 0.0 2.9 9.4 4.2 20.7 0.0 4.8 6.0 33.7 11.5 2.3 1.6 10.2 3.0 63.4 29.3 2.4 0.9 12.4 29.6 22.9 7.3 22.6 21.4 34.7 3.7 29.6 3.0 77.8 11.5 16.0 12.2 11.8 12.1 8.9 0.2 7.8 8.7 6.5 0.6 8.1 8.1 6.2 5.4 14.8 0.5 8.4 10.9 3.8 4.4 3.0 5.8 3.1 3.9 4.2 2.8 3.7 1.3 4.4 3.7 107.4 19.2 58.5 5.2 19.1 46.8 26.3 104.4 19.4 27.6 9.0 16.1 11.6 24.3 51.0 11.0 33.3 15.1 122.9 250.1 70.5 50.5 1.0 42.1 22.4 108.1 13.1 4.4 16.5 40.5 260.3 34.1 5.1 91.1 25.9 3.8 72.5 17.5 110.0 16.8 29.4 35.0 85.5 130.5 118.1 2.4 5.3 199.5 87.2 1.0 61.4 13.3 71.1 4.0 3.6 117.9 260.8 2.2 30.3 30.4 42.8 23.3 11.9 29.2 6.6 21.1 32.2 0.3 9.5 42.9 29.8 78.7 71.0 1.5 29.1 34.9 UQCR11 "QCR10, UQCR" ENSG00000127540 "Ubiquinol-cytochrome c reductase, complex III subunit XI" O14957 19 1597169-1605473 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 297.7;skeletal muscle: 311.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1792.1;Hepatocytes: 2200.3;Proximal enterocytes: 2007.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.90e-1)" "unprognostic (6.67e-3)" "unprognostic (1.78e-1)" "prognostic favorable (1.23e-4)" "unprognostic (5.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (5.42e-3)" "unprognostic (9.10e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.86e-4)" "unprognostic (1.03e-1)" "prognostic favorable (1.65e-4)" "unprognostic (2.40e-1)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (1.06e-2)" 71.0 80.2 74.9 20.6 79.6 39.7 60.5 79.4 103.7 46.8 78.6 91.7 59.7 46.4 18.4 71.6 43.6 25.0 297.7 76.4 76.7 103.4 136.4 48.7 27.4 76.5 77.7 35.5 49.5 46.8 62.7 24.1 76.6 62.0 22.8 13.8 53.9 30.9 311.8 50.4 62.6 22.6 75.6 60.9 77.2 24.7 78.3 24.1 52.6 109.7 19.3 60.9 51.4 79.0 68.9 75.7 34.7 74.5 60.8 40.7 79.9 54.3 45.4 55.5 48.8 121.5 47.3 47.4 51.8 41.8 12.3 46.8 55.5 61.0 26.5 65.0 163.1 40.6 87.3 114.0 60.6 66.1 57.9 62.8 62.6 35.2 41.6 28.6 50.8 66.9 94.8 73.1 36.2 111.5 67.7 72.4 94.8 59.2 176.0 40.4 36.2 148.9 74.6 158.4 69.6 65.9 39.3 86.4 99.7 27.9 59.3 65.1 66.7 44.3 30.0 129.9 57.7 110.4 101.2 54.4 82.6 69.9 64.8 619.6 421.3 521.9 282.7 367.9 287.1 390.0 341.7 316.6 360.5 333.8 324.3 314.1 496.7 273.7 354.9 448.4 407.7 872.4 74.9 79.6 79.4 103.7 76.4 76.7 76.5 77.7 76.6 75.6 78.3 79.0 300.4 269.2 379.1 20.5 287.6 0.0 189.6 0.0 206.6 135.2 715.6 798.8 1731.6 529.0 159.7 634.5 39.6 481.8 380.1 834.6 1792.1 665.4 178.2 290.5 220.2 282.4 452.6 451.6 17.8 811.6 632.1 262.0 342.0 243.5 199.3 152.6 463.3 2200.3 962.9 89.2 17.6 681.7 0.0 783.5 0.0 474.8 252.8 472.2 0.0 10.3 866.6 418.8 568.5 9.5 25.1 855.3 727.0 259.5 384.1 365.5 2007.4 1742.3 267.5 164.4 223.5 192.6 291.3 159.2 145.3 520.3 0.0 512.8 304.3 188.0 717.0 290.3 UQCRFS1 "RIP1, RIS1, RISP, UQCR5" ENSG00000169021 "Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1" P47985 19 29205320-29213151 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 231.6;tongue: 285.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1474.9;Distal tubular cells: 1035.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041863, HPA050339" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041863: AB_10794638, HPA050339: AB_2681095" "unprognostic (4.00e-2)" "unprognostic (2.23e-3)" "prognostic favorable (3.29e-4)" "unprognostic (7.91e-3)" "unprognostic (3.93e-2)" "unprognostic (8.68e-2)" "unprognostic (1.84e-1)" "unprognostic (7.53e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.92e-9)" "unprognostic (6.11e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (1.92e-2)" 28.7 50.1 25.6 17.4 26.7 52.8 24.7 29.4 31.1 18.3 33.6 49.0 43.2 19.2 23.1 33.2 19.3 13.2 138.3 27.2 28.4 62.5 50.9 17.6 17.2 27.0 27.4 15.4 29.4 47.3 19.9 17.3 26.1 18.8 52.6 26.6 26.7 21.9 231.6 27.9 34.0 24.8 26.4 21.1 39.3 25.9 29.3 26.0 16.8 285.9 25.9 25.7 20.3 26.0 63.0 103.7 37.7 34.1 60.6 45.9 41.8 47.8 49.7 64.7 71.1 63.3 37.7 56.7 49.2 54.4 52.7 64.8 83.4 56.9 77.6 38.7 83.2 80.2 39.2 58.1 51.3 77.2 67.5 55.5 60.4 44.2 66.9 38.0 52.4 69.0 58.0 34.5 70.2 58.0 54.5 57.6 39.6 132.2 39.7 48.9 50.3 43.1 80.9 74.4 45.8 22.4 43.5 84.9 58.2 42.0 39.6 63.4 33.4 43.5 66.4 30.2 50.4 16.4 33.3 52.5 38.4 66.4 31.7 51.4 90.7 43.8 50.0 90.9 50.3 54.8 53.2 51.9 106.6 48.0 56.1 53.6 27.3 49.2 78.3 59.3 68.4 166.2 25.6 26.7 29.4 31.1 27.2 28.4 27.0 27.4 26.1 26.4 29.3 26.0 69.7 54.5 46.6 16.6 104.9 147.6 279.7 466.7 105.9 71.8 119.5 128.4 1474.9 161.5 201.4 114.0 16.7 282.0 116.8 321.6 1035.0 245.2 258.4 106.1 66.8 106.8 160.0 147.9 18.1 235.1 271.7 126.7 139.7 88.5 90.7 114.2 83.9 272.1 266.1 52.2 19.2 293.6 317.3 160.6 109.6 146.0 92.2 136.6 165.4 13.1 206.6 124.6 132.8 19.6 15.8 205.0 225.8 81.6 159.4 257.3 338.6 758.4 132.4 84.1 98.6 107.5 131.0 348.8 80.5 203.9 160.3 381.9 109.5 209.1 407.4 372.1 UQCRH "QCR6, UQCR8" ENSG00000173660 "Ubiquinol-cytochrome c reductase hinge protein" P07919 1 46303698-46316776 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042574 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA042574: AB_10960998" "unprognostic (2.24e-2)" "unprognostic (6.48e-2)" "unprognostic (5.62e-2)" "unprognostic (1.06e-3)" "unprognostic (6.34e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (4.63e-5)" "unprognostic (1.31e-1)" "unprognostic (3.15e-2)" "unprognostic (2.56e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-3)" "unprognostic (2.07e-2)" "unprognostic (3.77e-1)" "unprognostic (5.14e-2)" "unprognostic (1.04e-1)" 216.1 159.7 403.2 200.3 408.4 414.5 241.5 420.6 533.0 176.6 423.5 433.1 396.6 153.6 215.7 292.8 121.1 134.9 1012.8 410.2 421.1 363.4 261.5 121.6 257.5 417.7 404.1 227.8 215.9 403.4 144.7 142.4 411.3 147.8 418.4 436.6 278.5 177.2 932.8 172.0 291.0 146.8 408.8 143.2 256.0 77.7 420.4 312.4 138.0 1033.3 349.6 237.6 188.9 408.4 766.7 456.4 514.3 945.2 529.0 720.3 1070.8 501.7 311.3 435.2 372.5 883.1 416.1 750.2 653.2 474.0 777.9 537.8 742.2 778.7 650.8 563.1 1262.1 1854.5 1320.9 1215.3 313.6 1832.0 508.1 810.8 466.3 706.7 363.4 643.0 622.6 907.5 1803.3 814.1 675.1 613.9 830.6 1884.9 3043.4 950.6 917.8 858.9 840.5 2386.6 974.1 1679.4 1008.3 1180.4 806.7 1519.3 1628.1 1346.7 507.4 2232.3 541.3 410.8 528.9 589.2 935.7 546.9 1230.5 1185.4 593.1 1432.2 625.9 171.5 372.6 249.0 214.4 332.7 281.9 544.6 307.8 283.6 481.5 433.1 346.2 313.0 69.3 221.4 297.8 318.2 340.7 620.8 403.2 408.4 420.6 533.0 410.2 421.1 417.7 404.1 411.3 408.8 420.4 408.4 249.6 105.8 148.5 26.4 523.3 457.8 703.8 1298.7 544.7 269.7 669.2 942.3 1897.2 479.0 505.3 393.6 166.8 651.5 273.8 761.5 2099.3 479.4 65.2 239.0 321.1 293.0 502.5 453.8 49.7 350.6 816.2 285.8 452.1 341.1 283.6 432.7 355.6 612.9 724.5 102.6 53.9 1148.6 612.3 711.1 410.1 69.1 308.8 516.2 489.2 12.2 606.2 408.1 365.6 22.1 22.2 419.9 789.0 284.4 703.3 710.0 944.4 1521.9 213.3 454.0 328.7 358.3 372.6 184.3 337.8 935.4 526.9 650.2 318.0 396.5 1298.2 866.4 USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 41.5;Endothelial cells: 28.3;Hepatic stellate cells: 21.4;Ionocytes: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 10.9;HeLa: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" 8.8 1.9 5.0 1.6 4.9 2.9 8.2 7.2 5.2 2.9 4.1 1.9 1.9 3.6 1.1 1.3 3.1 1.7 12.6 5.0 4.1 4.5 1.2 6.9 2.6 4.6 4.5 1.4 4.8 0.8 1.2 5.6 5.1 2.3 0.5 1.1 2.0 0.9 6.2 2.1 2.2 1.3 3.3 3.5 1.7 1.0 5.1 0.5 4.5 4.8 0.5 2.8 2.3 4.6 0.6 0.9 1.7 0.4 0.0 0.0 10.9 0.3 0.0 0.0 0.0 1.9 0.9 2.9 3.4 0.0 0.1 1.2 0.1 0.2 0.0 0.7 1.3 0.7 5.0 1.1 0.0 2.4 2.4 0.3 0.0 0.2 0.2 0.6 3.2 1.1 1.4 1.5 0.0 0.1 0.4 2.4 1.3 0.3 2.7 1.4 0.2 0.7 0.0 1.3 1.1 0.7 0.7 0.7 0.2 0.9 1.3 0.9 1.9 1.8 0.5 1.5 1.0 2.6 0.9 2.8 0.6 1.5 0.6 2.0 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.7 0.1 1.0 0.9 0.8 1.6 0.7 0.2 0.8 0.8 0.5 5.0 4.9 7.2 5.2 5.0 4.1 4.6 4.5 5.1 3.3 5.1 4.6 41.5 3.2 0.5 0.7 0.0 0.5 0.9 0.1 0.6 0.3 0.5 0.1 6.7 0.0 0.7 0.0 0.0 1.1 3.1 0.2 0.0 0.1 0.7 0.7 0.8 28.3 0.0 0.0 0.4 0.6 0.9 0.9 0.0 1.5 1.3 0.1 21.4 0.3 0.1 0.0 0.5 0.2 20.3 0.6 1.2 0.2 0.6 0.3 5.4 6.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 1.3 0.1 1.7 0.0 2.2 1.5 0.2 0.4 0.2 1.0 4.5 0.7 0.3 0.0 0.8 UST 2OST ENSG00000111962 "Uronyl 2-sulfotransferase" Q9Y2C2 6 148747030-149076990 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 339.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 32.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032022 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "HPA032022: AB_10603326" "unprognostic (3.43e-1)" "unprognostic (1.90e-1)" "unprognostic (7.87e-3)" "unprognostic (3.22e-5)" "unprognostic (1.83e-3)" "unprognostic (1.50e-1)" "unprognostic (5.71e-2)" "unprognostic (1.96e-2)" "unprognostic (8.31e-3)" "unprognostic (2.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.11e-1)" "unprognostic (9.25e-3)" "unprognostic (9.48e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (3.02e-2)" 6.0 12.2 6.3 3.0 7.4 0.2 6.2 10.0 7.9 7.6 7.5 9.2 1.7 6.8 5.6 4.6 9.2 6.0 4.3 5.8 16.0 3.6 1.3 5.2 3.9 28.2 17.2 11.6 13.1 4.6 1.9 4.6 14.1 6.3 2.7 6.8 3.2 4.8 1.7 6.7 5.7 8.8 13.5 6.5 5.0 6.7 22.7 6.5 27.5 5.8 3.7 8.8 7.7 15.6 0.1 3.2 18.2 14.0 21.5 17.8 0.1 7.9 20.5 3.8 9.8 0.0 1.2 6.7 1.7 12.3 9.5 5.7 13.0 6.6 7.6 9.1 9.9 0.2 10.0 0.1 7.9 0.3 2.8 9.2 14.6 9.8 18.1 7.6 0.2 11.1 0.0 0.0 3.0 8.3 0.1 0.0 10.7 32.4 4.2 3.3 2.5 7.7 0.1 14.8 9.4 0.0 26.4 6.3 5.0 13.0 4.7 0.3 0.4 10.9 1.3 2.5 7.4 0.0 0.0 0.0 12.1 5.4 6.3 0.0 0.0 0.0 0.6 0.2 0.4 0.3 0.4 0.5 0.4 0.5 0.0 0.2 0.0 2.5 0.3 0.4 0.1 0.1 6.3 7.4 10.0 7.9 5.8 16.0 28.2 17.2 14.1 13.5 22.7 15.6 0.9 3.2 3.2 70.2 4.5 9.4 5.4 2.6 3.4 0.1 1.7 1.5 1.7 0.0 2.7 1.8 0.0 2.0 8.9 0.2 0.0 0.1 1.1 0.3 8.7 0.6 0.0 0.0 36.3 2.0 0.3 16.3 7.1 0.4 0.0 12.3 1.4 0.3 1.7 0.0 39.7 1.8 10.2 1.0 20.9 3.4 18.3 2.8 5.4 80.6 1.0 14.6 5.2 339.8 3.2 1.1 0.3 11.3 0.4 5.9 0.0 0.6 2.3 0.8 0.0 6.8 3.5 2.9 5.7 1.9 11.6 1.4 2.0 10.2 0.5 6.8 VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 487.9;Endothelial cells: 337.8;Hepatic stellate cells: 486.2;Kupffer cells: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 364.7;LHCN-M2: 428.9;TIME: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" 134.0 117.4 71.0 59.9 74.1 41.2 118.4 72.9 89.1 78.6 66.8 76.4 23.3 79.4 33.2 45.3 84.3 58.0 114.7 69.4 76.1 90.0 79.3 134.6 92.7 79.1 71.4 52.8 29.0 14.7 31.9 74.1 74.2 72.8 20.5 2.9 36.9 36.7 217.3 44.5 54.1 77.2 73.8 97.5 54.0 11.4 78.0 50.9 63.8 199.6 41.2 87.1 69.7 71.7 0.8 0.2 2.4 0.0 89.3 155.8 2.4 98.5 155.9 95.5 104.5 39.5 15.1 0.3 2.3 172.2 50.7 1.1 0.0 2.4 42.2 142.9 2.8 1.9 2.5 56.1 187.2 4.5 0.9 108.4 9.6 40.1 1.1 138.9 364.7 61.7 0.4 0.3 428.9 14.5 63.1 13.8 0.1 27.2 0.6 92.4 0.4 2.7 2.7 3.6 0.2 3.4 0.6 27.4 0.5 2.2 3.2 5.1 250.0 2.3 6.7 7.5 0.2 0.1 3.1 2.4 110.5 5.4 65.9 59.1 222.6 176.5 180.5 503.8 171.7 60.7 136.1 135.2 79.0 54.5 102.4 125.1 70.2 94.4 424.9 86.4 248.7 283.0 71.0 74.1 72.9 89.1 69.4 76.1 79.1 71.4 74.2 73.8 78.0 71.7 487.9 19.2 21.2 3.6 43.9 60.8 39.8 104.1 39.3 0.8 14.9 27.3 84.4 71.4 70.1 44.1 0.0 22.9 64.5 38.8 29.4 29.9 1.8 7.7 64.7 337.8 12.6 35.6 0.1 49.1 7.2 148.0 9.7 7.9 44.4 22.2 486.2 198.6 80.3 3.3 0.2 20.5 36.7 340.8 91.5 10.2 192.6 147.8 275.7 4.7 136.0 17.5 112.3 0.5 1.6 44.2 51.9 165.1 68.4 64.7 126.5 91.2 50.6 1.0 59.2 152.2 83.9 5.5 6.6 19.8 45.3 21.6 88.5 19.2 7.8 49.4 VAMP8 EDB ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 873.4;NB-4: 1362.5;U-937: 912.8" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" 74.0 34.7 26.9 148.4 28.2 299.7 225.1 28.7 53.8 121.8 51.6 250.6 229.9 30.6 144.5 303.1 166.1 119.2 24.6 26.5 29.9 280.1 247.4 266.5 212.4 35.6 31.6 10.4 182.5 270.3 33.7 265.7 34.3 107.7 300.9 4.4 322.5 90.4 24.3 210.2 252.1 71.4 31.9 175.9 228.4 23.4 35.5 173.5 126.0 27.3 311.7 198.0 150.0 36.5 255.0 33.2 2.6 2.3 2.4 1.4 241.6 0.7 0.3 0.2 0.3 191.2 225.2 56.8 174.4 1.2 17.9 175.2 2.4 451.6 0.6 232.3 173.7 290.3 104.4 220.7 3.3 873.4 287.1 2.3 317.5 0.3 72.3 1.2 58.2 1.2 214.9 11.6 103.8 363.9 0.8 1362.5 3.2 315.9 26.0 5.2 8.9 381.7 516.9 384.3 8.4 2.9 120.9 628.3 19.4 126.3 231.4 665.4 113.9 0.3 15.3 2.9 2.7 3.0 151.1 340.0 2.6 912.8 1.1 601.3 868.6 328.4 469.3 740.3 455.6 519.3 537.0 463.3 787.3 508.3 423.2 442.0 52.4 556.3 460.0 2135.6 665.3 1536.0 26.9 28.2 28.7 53.8 26.5 29.9 35.6 31.6 34.3 31.9 35.5 36.5 39.4 371.8 283.2 1.3 147.7 259.1 303.3 800.9 164.4 1.2 289.7 251.7 6.3 356.0 662.1 366.0 0.0 980.8 447.1 832.3 765.0 630.7 28.0 231.3 22.8 46.1 129.1 147.4 0.1 730.0 460.4 35.6 188.6 212.9 269.4 3.3 163.1 314.8 1191.1 0.0 0.1 391.8 545.3 1000.4 488.7 49.1 9.3 537.2 352.2 2.8 686.1 7.9 375.9 0.0 0.5 865.5 843.2 7.5 103.0 302.7 1184.0 1046.8 600.5 2.0 46.0 21.4 56.5 48.0 8.3 239.8 329.7 877.8 219.5 13.8 299.4 602.0 VCL ENSG00000035403 Vinculin P18206 10 73995193-74121363 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 339.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 568.3;hTERT-RPE1: 547.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002131, CAB002453, HPA063777" Enhanced Enhanced "Focal adhesion sites" NA NA 750000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites" "CAB002453: AB_564057, HPA002131: AB_1080570, HPA063777: AB_2685121" "unprognostic (8.49e-2)" "unprognostic (1.61e-2)" "unprognostic (3.14e-1)" "unprognostic (6.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.62e-3)" "unprognostic (2.72e-3)" "unprognostic (2.67e-3)" "unprognostic (3.42e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (4.03e-2)" "unprognostic (4.02e-2)" "unprognostic (1.89e-1)" "unprognostic (1.37e-3)" 85.8 19.1 9.9 52.2 10.6 41.5 45.3 8.4 11.3 73.9 33.4 180.3 35.3 167.6 45.9 92.2 75.9 69.4 132.2 10.5 11.3 37.2 24.1 68.7 18.7 10.3 10.3 45.2 40.3 51.3 13.8 88.6 13.3 131.7 73.1 12.5 31.6 151.9 136.9 37.9 52.7 224.7 9.9 41.9 63.5 41.3 12.1 12.8 39.6 144.1 23.9 135.7 56.3 8.4 147.2 97.0 174.2 123.8 213.2 246.2 95.8 188.5 568.3 126.3 141.9 88.4 124.0 6.5 153.1 331.6 86.3 183.3 115.7 95.0 132.5 12.3 49.6 69.4 92.2 37.2 116.5 14.1 101.8 205.0 25.0 171.5 154.8 547.4 171.0 11.6 50.7 14.3 213.1 25.2 2.0 16.6 82.8 69.9 342.4 24.0 90.9 18.6 180.4 185.8 6.5 25.8 104.7 117.2 53.9 152.8 54.5 21.2 230.9 136.9 57.0 67.0 179.4 2.6 6.0 28.4 160.0 38.9 39.7 15.0 13.6 36.2 14.9 17.1 10.4 5.6 7.1 7.8 20.7 2.3 2.6 5.3 11.2 4.4 19.0 8.0 1.9 28.3 9.9 10.6 8.4 11.3 10.5 11.3 10.3 10.3 13.3 9.9 12.1 8.4 68.0 99.3 39.7 56.5 13.4 114.7 161.4 68.4 30.7 13.4 39.4 58.5 339.5 37.1 79.8 42.3 85.5 51.5 46.7 91.2 3.9 60.8 5.0 98.2 152.6 60.4 38.3 5.9 63.2 61.6 78.6 74.4 66.3 149.1 35.4 45.5 56.7 34.4 23.6 16.8 47.5 44.5 22.4 31.9 51.0 7.5 50.1 77.9 26.6 55.3 44.7 9.7 61.8 18.6 4.6 125.5 48.3 76.8 8.0 100.1 13.7 14.8 37.7 34.5 105.2 49.6 179.9 18.6 13.7 45.6 93.1 39.7 18.3 44.5 48.7 94.8 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.9;Muller glia cells: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 209.8 82.0 45.7 12.0 51.3 3.9 151.3 41.8 53.1 103.6 48.2 151.5 12.1 99.9 7.2 50.8 72.5 19.2 253.3 38.7 45.1 84.6 44.0 82.5 14.4 54.8 47.4 82.6 84.9 18.3 104.2 9.8 45.0 92.7 4.7 12.7 57.7 28.5 143.8 77.3 59.5 10.2 44.2 55.9 89.2 17.5 50.6 6.6 83.7 51.5 9.1 118.0 77.5 37.3 15.4 25.9 9.9 28.1 49.7 36.8 12.7 14.7 27.8 13.1 16.0 13.8 31.7 19.8 28.6 14.0 28.8 20.8 15.8 11.5 2.3 20.6 15.1 16.7 33.9 13.3 45.4 4.8 20.1 39.6 12.0 19.6 12.2 33.9 18.4 20.6 20.2 32.5 22.2 31.8 27.4 12.6 7.0 10.9 22.3 32.1 20.5 46.5 11.0 19.5 14.0 46.4 12.4 38.1 57.4 7.6 25.1 5.6 13.0 50.8 30.2 23.1 8.7 90.5 45.5 15.4 41.6 5.3 25.1 0.3 0.2 0.6 0.9 0.0 0.8 3.0 0.8 0.9 0.4 2.4 0.9 1.6 0.0 0.4 0.0 30.5 0.5 0.4 45.7 51.3 41.8 53.1 38.7 45.1 54.8 47.4 45.0 44.2 50.6 37.3 54.1 19.2 32.6 43.8 27.6 12.7 6.7 10.1 2.2 47.9 32.8 65.7 204.9 10.0 7.6 14.7 33.3 9.6 68.3 11.9 39.2 14.8 1.1 24.2 47.7 21.9 53.3 4.4 7.3 12.9 16.8 68.6 5.1 31.6 18.4 62.7 19.6 9.8 51.4 65.6 26.6 12.2 20.3 31.5 21.5 3.5 60.9 50.0 35.6 19.7 17.7 130.6 12.3 29.1 11.8 14.5 7.3 109.1 12.3 11.5 20.3 31.6 8.9 39.6 6.6 47.4 53.7 0.5 1.2 6.4 13.9 8.9 19.0 34.3 12.8 7.5 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 454.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 749.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 638.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 99.4 107.6 56.0 38.4 60.4 55.2 87.0 60.3 73.5 111.0 64.9 97.0 44.2 109.9 87.2 51.8 90.8 58.9 99.1 57.4 59.3 122.7 454.9 77.4 35.8 64.4 59.5 115.1 168.0 51.3 115.7 45.6 63.8 76.3 41.1 23.0 92.4 69.8 34.4 81.1 82.3 84.7 59.9 62.2 88.1 55.6 68.5 35.0 76.3 32.2 32.6 100.6 88.0 64.8 73.6 187.7 57.2 165.4 638.0 389.6 68.2 269.0 229.3 128.9 218.5 79.0 83.3 54.9 141.6 331.6 87.2 66.2 79.4 103.5 139.5 81.9 204.8 52.5 239.9 378.2 103.1 104.1 74.1 225.0 54.2 173.4 146.6 336.8 141.0 78.2 70.3 130.6 253.6 271.1 74.4 205.9 106.8 98.0 175.9 132.7 160.3 286.8 127.7 61.8 119.5 146.9 118.7 84.2 137.8 91.2 138.3 123.9 126.8 171.1 61.5 159.6 101.9 76.1 80.2 50.7 445.8 174.5 90.8 77.0 127.5 196.2 118.1 94.7 116.8 91.7 116.7 119.4 127.6 102.6 102.9 101.4 104.0 84.2 98.2 157.4 143.1 112.8 56.0 60.4 60.3 73.5 57.4 59.3 64.4 59.5 63.8 59.9 68.5 64.8 95.1 57.7 51.0 5.9 30.6 84.6 68.0 157.0 10.8 12.3 93.3 117.3 20.9 141.5 64.3 108.5 8.4 85.7 48.1 34.3 62.6 204.2 6.1 25.8 83.7 89.5 67.1 32.4 8.8 129.4 293.6 132.8 10.7 48.8 55.3 60.3 118.9 749.9 184.1 10.1 7.5 44.2 46.8 80.1 94.3 13.9 158.1 66.9 115.6 5.6 107.4 68.8 51.5 6.6 17.6 103.8 28.2 172.3 29.5 59.5 152.9 204.6 33.4 19.3 59.2 78.4 99.8 30.6 34.2 10.7 112.0 39.5 39.7 82.4 49.0 55.2 VKORC1L1 ENSG00000196715 "Vitamin K epoxide reductase complex subunit 1 like 1" Q8N0U8 7 65873074-65959563 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053954 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA053954: AB_2682319" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (4.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-3)" "unprognostic (7.15e-3)" "unprognostic (1.30e-3)" "unprognostic (8.84e-3)" "unprognostic (5.12e-2)" "unprognostic (5.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.07e-1)" "unprognostic (1.59e-2)" "unprognostic (1.17e-1)" "unprognostic (7.03e-3)" "unprognostic (4.30e-1)" "unprognostic (5.06e-2)" 54.0 11.1 8.1 11.2 9.0 4.3 23.7 8.3 12.1 12.0 3.7 12.4 11.1 12.3 10.6 12.5 10.0 10.0 12.1 10.1 9.2 10.0 22.9 18.4 8.7 18.1 10.5 17.3 9.7 33.6 6.7 12.0 10.5 12.0 12.5 11.5 10.9 12.4 21.6 12.8 11.6 11.6 8.9 7.4 12.8 9.1 8.5 9.7 13.9 15.3 8.7 11.9 9.6 9.6 46.8 29.5 23.4 29.5 72.6 28.6 42.3 49.5 31.8 29.0 29.1 28.7 44.9 40.4 39.0 35.7 43.9 31.2 33.6 20.1 47.9 25.5 33.1 27.6 25.4 24.7 35.4 38.7 20.3 23.2 25.3 29.5 40.7 22.5 29.2 22.6 59.0 30.0 34.9 18.3 31.8 44.8 56.1 43.8 22.0 34.5 34.0 50.5 28.0 18.5 28.0 39.8 38.3 68.5 21.8 32.8 34.5 29.5 33.3 46.6 32.0 29.5 51.0 26.9 47.1 46.1 28.6 43.0 41.6 2.0 1.1 2.7 1.2 1.1 1.0 1.3 1.5 1.4 1.3 1.1 0.9 0.9 1.3 2.9 2.2 3.5 1.5 0.7 8.1 9.0 8.3 12.1 10.1 9.2 18.1 10.5 10.5 8.9 8.5 9.6 19.5 73.7 41.7 16.6 5.5 24.9 18.6 16.2 9.6 21.8 18.6 15.9 21.5 27.1 24.2 16.5 12.5 12.5 10.0 27.1 5.9 18.1 39.0 13.7 23.8 17.1 13.8 26.1 42.7 24.8 21.2 22.6 19.4 25.3 5.1 24.1 10.8 46.9 16.0 30.3 36.6 26.4 20.3 6.6 10.2 9.1 17.7 12.9 7.2 28.1 10.0 11.6 7.2 26.7 34.6 31.6 8.2 18.4 15.6 36.3 14.4 11.4 11.7 20.2 6.6 24.9 26.4 18.5 7.2 17.9 32.0 8.8 6.6 10.8 20.3 22.6 VPREB1 "CD179A, VpreB" ENSG00000169575 "V-set pre-B cell surrogate light chain 1" P12018 22 22244780-22245515 "CD markers, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "bone marrow: 29.8" "Cell type enhanced" "Detected in single" "NK-cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 5.7;naive B-cell: 5.3" "Lineage enriched" "Detected in many" 4 "B-cells: 5.7" "Group enriched" "Detected in some" 11 "Daudi: 9.4;MOLT-4: 19.8;RPMI-8226: 5.4" "Not detected" "Not detected" HPA055886 Approved "Intracellular and membrane" NA NA 62000 "Cluster 37: B-cells - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA055886: AB_2682956" 0.0 0.0 0.0 0.0 0.0 29.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 VPS25 "DERP9, EAP20, MGC10540" ENSG00000131475 "Vacuolar protein sorting 25 homolog" Q9BRG1 17 42773449-42779599 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004978, HPA021992, HPA052217, HPA057284" Uncertain Supported Vesicles NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004978: AB_426095, HPA021992: , HPA052217: AB_2681765, HPA057284: AB_2683397" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-4)" "unprognostic (7.37e-2)" "unprognostic (7.57e-2)" "unprognostic (9.83e-3)" "unprognostic (2.76e-3)" "unprognostic (5.84e-2)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (8.10e-3)" "unprognostic (3.88e-1)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" 36.6 40.3 32.8 32.5 33.0 44.3 53.3 34.8 36.8 41.6 36.6 61.9 53.8 35.5 65.3 91.4 58.9 33.4 43.5 32.9 33.2 70.1 68.6 31.8 37.8 32.9 32.8 33.2 49.0 72.3 27.6 46.7 33.5 40.2 68.4 31.2 48.7 36.5 51.3 50.5 45.4 42.8 33.5 37.1 50.0 27.4 33.8 51.3 40.9 41.3 57.2 44.8 44.3 34.0 67.2 136.6 101.8 62.1 126.9 86.5 94.5 83.0 117.1 167.5 116.3 117.9 77.0 66.8 135.8 122.0 88.5 68.7 142.2 181.8 107.9 61.2 178.7 50.6 87.0 177.5 131.0 95.7 64.6 118.2 115.4 148.9 158.0 99.1 106.7 79.0 175.6 65.5 102.1 96.5 138.8 105.2 78.9 152.0 95.3 51.1 123.3 108.7 202.6 75.8 86.3 66.7 46.8 60.1 129.6 155.8 138.4 100.2 58.0 105.7 68.4 60.0 90.3 64.0 39.4 97.9 92.7 64.5 79.6 85.1 76.9 106.7 38.8 89.0 39.9 48.8 42.4 46.4 80.3 46.6 42.3 40.7 44.9 78.9 82.7 54.1 43.1 59.6 32.8 33.0 34.8 36.8 32.9 33.2 32.9 32.8 33.5 33.5 33.8 34.0 26.3 25.6 36.3 4.2 25.3 13.9 41.0 88.3 16.5 24.1 44.4 46.6 26.9 51.5 65.7 62.5 14.6 136.1 22.0 74.3 133.1 135.9 2.6 61.8 48.5 35.4 41.0 47.9 3.5 152.4 186.5 40.8 40.8 55.9 29.2 21.5 29.6 46.4 102.3 23.5 3.5 70.5 85.5 34.5 12.7 5.6 27.7 33.0 42.7 0.0 46.7 56.1 44.3 2.5 4.7 134.4 75.7 30.5 40.9 44.4 83.5 93.6 74.9 29.5 32.9 13.5 69.9 42.8 46.7 61.9 22.9 121.6 22.8 69.9 63.4 53.5 VPS35L "C16orf62, MGC16824" ENSG00000103544 "VPS35 endosomal protein sorting factor like" Q7Z3J2 16 19555240-19706793 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 32.4;Cytotrophoblasts: 29.4;Distal tubular cells: 29.4;Hofbauer cells: 44.9;Syncytiotrophoblasts: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042969, HPA053547" Uncertain Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042969: AB_10794920, HPA053547: AB_2682183" "unprognostic (7.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.17e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (2.74e-1)" "unprognostic (2.52e-1)" "unprognostic (1.22e-3)" "unprognostic (3.57e-2)" "unprognostic (2.06e-1)" "prognostic favorable (1.31e-8)" "unprognostic (1.82e-3)" "unprognostic (8.92e-2)" "unprognostic (5.08e-2)" "unprognostic (1.13e-2)" 19.3 22.7 23.3 15.9 33.5 13.2 17.1 21.8 24.9 21.2 11.7 19.2 13.7 20.1 22.4 16.8 19.2 17.5 17.8 20.7 23.5 22.2 14.4 16.2 14.6 23.3 24.4 23.3 16.5 35.6 20.4 20.2 24.6 15.9 19.4 16.1 12.4 18.9 22.2 13.8 15.3 25.1 20.5 17.2 13.3 31.5 28.0 16.1 22.7 25.2 16.6 18.3 15.6 40.3 22.3 37.5 35.7 28.4 44.2 60.1 5.8 32.5 52.3 33.9 38.9 6.4 37.0 27.1 67.4 51.7 0.2 6.2 27.5 16.7 36.5 1.6 15.7 16.4 32.6 0.6 57.4 25.9 31.6 43.9 24.4 31.7 21.5 48.2 54.4 13.2 22.3 6.2 55.7 15.7 23.0 7.2 24.8 3.9 5.1 19.6 11.7 7.1 38.6 5.2 21.8 22.1 43.7 1.5 18.6 27.2 12.9 22.2 61.0 17.4 16.2 25.7 3.7 23.8 45.2 10.6 33.6 21.1 27.5 26.5 35.3 16.5 18.9 42.0 23.5 14.7 18.0 18.8 42.6 23.5 21.0 18.6 4.2 37.6 37.7 11.5 21.6 28.5 23.3 33.5 21.8 24.9 20.7 23.5 23.3 24.4 24.6 20.5 28.0 40.3 32.4 6.4 16.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 9.5 9.1 0.0 0.0 8.1 16.5 0.0 29.4 5.0 0.0 29.4 20.4 0.0 8.2 15.8 15.5 0.0 0.0 0.0 17.0 19.5 8.1 0.0 11.1 3.8 18.1 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 10.5 0.0 0.0 1.2 0.0 0.0 21.9 2.9 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 40.2 3.4 21.0 0.0 0.0 VSIG2 "CTH, CTXL" ENSG00000019102 "V-set and immunoglobulin domain containing 2" Q96IQ7 11 124747474-124752255 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "stomach 1: 619.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 514.3;Gastric mucus-secreting cells: 623.4;Intestinal goblet cells: 285.6;Pancreatic endocrine cells: 260.2;Paneth cells: 509.9;Undifferentiated cells: 207.0;Urothelial cells: 285.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 87.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 6 "OE19: 429.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035919, HPA050147" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 39: Non-specific - mRNA processing" "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA035919: AB_10669981, HPA050147: AB_2681032" "unprognostic (1.64e-3)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-1)" "unprognostic (2.18e-3)" "unprognostic (2.16e-1)" "unprognostic (2.22e-2)" "unprognostic (3.47e-3)" "unprognostic (2.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-2)" "unprognostic (2.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-2)" 6.5 0.8 3.1 7.0 6.4 3.4 9.5 0.8 7.1 29.7 0.2 136.2 6.2 4.9 0.4 26.4 17.5 26.5 5.3 2.8 1.5 6.3 3.0 45.7 0.9 1.7 3.6 1.1 2.0 1.9 1.7 6.0 2.0 58.2 137.8 0.6 31.8 4.3 2.3 1.5 2.8 4.7 1.1 1.6 619.2 0.9 3.1 0.2 43.7 2.5 2.5 84.5 9.3 3.6 0.4 0.1 4.8 3.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.9 1.5 2.4 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.3 16.6 0.0 7.9 0.7 0.5 3.0 0.1 0.0 0.0 0.0 0.3 2.8 0.3 0.3 0.6 0.0 1.6 0.1 0.1 0.6 429.0 3.7 0.4 3.6 0.1 0.1 69.2 0.3 0.9 0.1 4.6 0.0 0.7 0.4 2.4 4.1 1.8 1.1 0.3 0.8 0.3 0.0 0.0 0.6 1.7 0.9 0.0 1.2 0.0 0.0 0.1 0.5 0.0 0.5 0.1 0.4 0.0 0.6 0.4 0.1 0.3 0.2 0.0 0.7 0.9 3.1 6.4 0.8 7.1 2.8 1.5 1.7 3.6 2.0 1.1 3.1 3.6 4.6 125.0 51.6 0.0 1.5 0.8 19.2 25.3 2.8 1.5 31.5 18.4 0.7 82.9 99.3 3.7 0.0 0.0 0.6 514.3 1.9 14.6 0.0 12.1 1.8 5.0 66.8 0.0 0.2 90.9 0.1 0.9 623.4 18.3 1.3 0.1 3.9 0.2 0.1 0.0 0.1 285.6 20.3 0.3 2.7 0.0 1.5 2.4 3.6 1.0 0.0 0.0 0.0 0.0 0.1 260.2 509.9 0.0 0.7 61.6 1.3 0.1 36.7 0.0 0.0 0.3 6.2 0.2 0.7 0.7 0.4 0.0 2.2 0.3 207.0 285.3 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 663.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 442.7;Inhibitory neurons: 243.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 663.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 125.9;Hep G2: 124.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053808: AB_2682270" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.90e-4)" "unprognostic (4.90e-2)" "unprognostic (5.48e-2)" "unprognostic (2.81e-2)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-1)" "unprognostic (5.14e-4)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.19e-3)" "unprognostic (1.51e-2)" 0.8 27.5 100.4 1.4 143.0 0.1 6.2 12.9 663.3 13.5 0.0 4.6 0.2 1.1 0.0 47.9 2.0 0.2 39.7 105.8 12.3 1.9 20.8 2.9 0.1 21.6 0.0 3.6 1.2 0.2 2.7 5.4 19.7 3.9 5.4 18.6 9.7 0.8 1.3 13.8 0.3 1.1 0.0 0.3 1.4 0.8 4.3 1.1 0.8 2.9 7.3 1.5 26.3 188.8 0.7 0.1 1.4 21.2 2.4 3.0 0.1 0.0 0.0 0.0 0.6 0.3 13.6 0.0 0.0 0.0 0.0 125.9 0.8 4.0 0.0 0.0 0.5 0.0 0.1 124.4 0.0 0.0 0.3 0.9 6.0 0.0 2.9 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 0.1 21.0 6.7 0.0 0.1 0.1 0.0 0.0 0.4 9.3 8.5 0.0 0.0 0.0 4.9 0.0 0.1 0.0 4.2 0.0 0.0 2.4 0.1 0.0 0.0 3.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 143.0 12.9 663.3 105.8 12.3 21.6 0.0 19.7 0.0 4.3 188.8 0.1 0.0 0.5 41.1 0.0 18.2 29.8 54.3 59.2 8.8 4.9 19.7 30.8 4.3 18.0 0.0 0.0 0.3 0.1 2.2 1.9 0.1 5.1 0.0 0.1 1.1 1.2 0.0 442.7 0.2 0.2 5.9 0.0 0.1 0.0 0.1 0.0 17.8 0.6 3.3 243.2 7.1 18.3 0.3 0.8 6.5 0.6 0.5 3.6 54.4 0.6 3.7 0.0 36.7 42.9 0.2 1.0 0.0 0.0 15.0 0.0 4.0 0.8 14.7 0.0 0.2 1.3 1.7 0.9 85.5 20.2 0.4 0.8 1.8 5.6 14.2 VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Granulosa cells: 96.9;Late spermatids: 140.6;Sertoli cells: 59.2;Theca cells: 44.7" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 8.6;RH-30: 9.3;SH-SY5Y: 7.9;U-138 MG: 10.6;U-2197: 24.0;U-87 MG: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" 18.7 41.5 7.1 3.2 9.0 0.3 9.8 8.0 6.6 22.3 7.7 7.8 2.5 12.3 7.4 7.8 8.5 10.5 12.3 6.2 7.6 12.3 3.9 10.9 3.5 8.9 9.3 35.2 1.5 26.8 5.1 10.4 9.2 13.5 5.6 2.3 3.4 11.7 5.6 4.9 4.9 11.4 8.6 2.3 5.6 9.4 8.4 6.5 27.8 5.9 4.6 12.0 7.5 9.4 0.0 0.0 3.1 0.1 1.3 0.7 0.1 2.6 4.1 0.9 0.2 0.0 0.1 0.1 0.1 6.1 3.4 0.1 0.2 0.0 0.4 3.2 1.4 0.2 0.1 0.1 0.1 0.1 0.0 4.7 0.0 4.2 0.0 0.0 0.0 0.8 8.6 0.1 0.8 0.1 0.0 0.2 0.6 0.0 0.0 0.0 9.3 5.0 0.0 0.1 0.1 7.9 0.1 0.0 0.0 0.4 0.1 0.3 0.0 10.6 1.2 24.0 0.1 0.0 6.8 0.0 11.6 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.3 0.1 0.1 0.0 0.0 7.1 9.0 8.0 6.6 6.2 7.6 8.9 9.3 9.2 8.6 8.4 9.4 9.4 3.2 17.5 17.3 1.3 6.5 1.6 0.1 0.6 5.4 1.2 1.1 16.7 0.0 9.4 0.0 2.1 0.4 3.7 0.2 1.9 0.1 88.5 0.8 10.7 6.2 0.0 0.0 11.1 0.0 0.3 29.7 0.0 0.7 12.6 96.9 5.3 5.0 0.7 5.0 7.0 0.0 0.0 2.2 11.1 140.6 9.6 2.9 7.2 4.7 1.0 9.1 2.1 20.1 33.3 0.2 0.1 14.7 0.7 0.8 0.0 9.4 3.8 2.9 59.2 20.6 37.7 1.3 4.4 0.4 4.3 0.4 2.0 44.7 0.0 0.7 VTI1B VTI2 ENSG00000100568 "Vesicle transport through interaction with t-SNAREs 1B" Q9UEU0 14 67647085-67674820 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 493.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044121, HPA048150, HPA060118" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA044121: AB_2678819, HPA048150: AB_2680288, HPA060118: AB_2684206" "unprognostic (2.26e-1)" "unprognostic (4.83e-2)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (3.00e-2)" "unprognostic (2.36e-3)" "unprognostic (3.25e-3)" "unprognostic (9.12e-2)" "unprognostic (1.90e-2)" "unprognostic (3.86e-1)" "unprognostic (2.60e-1)" "unprognostic (2.11e-2)" "prognostic favorable (3.53e-12)" "unprognostic (8.35e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (8.02e-3)" 53.8 26.9 55.5 20.4 56.8 22.3 39.8 54.4 102.1 22.7 49.8 42.9 28.3 18.4 53.5 44.3 18.5 28.7 60.1 56.6 58.1 53.0 41.6 26.8 23.8 55.1 56.6 21.0 44.0 23.9 17.1 21.3 56.8 22.3 35.2 23.0 30.1 13.6 46.5 31.0 24.1 22.4 56.0 26.5 40.0 30.8 56.3 12.1 34.0 28.2 27.0 33.3 23.4 56.9 111.7 54.8 31.4 18.1 61.9 37.2 45.4 48.1 30.5 23.8 23.7 27.3 38.5 32.9 40.2 54.5 27.5 30.6 36.8 36.6 37.7 34.3 22.6 33.4 32.5 34.8 26.6 20.9 22.9 36.3 39.6 25.6 26.1 60.5 27.2 23.1 22.2 25.4 34.5 131.1 26.6 77.7 20.3 76.6 88.0 31.8 35.6 12.2 35.1 65.0 17.4 35.5 33.8 45.5 71.4 23.7 41.9 58.0 38.5 62.6 93.8 51.4 45.6 23.8 27.8 53.2 52.9 38.9 29.0 88.8 61.5 143.8 49.4 80.4 42.4 49.0 43.1 51.1 59.6 43.0 40.5 50.3 27.2 56.4 70.2 38.6 60.2 58.3 55.5 56.8 54.4 102.1 56.6 58.1 55.1 56.6 56.8 56.0 56.3 56.9 47.6 25.6 35.0 13.1 48.7 42.3 61.4 91.7 33.0 23.2 82.2 65.4 30.5 67.2 64.4 66.2 22.9 107.4 47.5 138.2 217.2 109.1 141.7 58.5 43.2 51.5 46.6 102.7 15.8 131.4 167.9 51.6 40.8 49.5 64.0 43.6 73.9 95.3 131.4 15.2 18.2 96.0 50.8 99.8 49.2 493.5 41.7 80.9 71.2 11.2 121.6 65.4 78.2 13.6 17.1 130.7 119.4 39.9 51.0 120.5 165.4 268.6 55.3 44.8 19.7 36.5 58.2 104.5 57.2 58.2 52.8 125.9 46.8 35.5 91.9 124.6 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 324.4" "Cell type enhanced" "Detected in some" "Adipocytes: 66.4;Cytotrophoblasts: 16.5;Endothelial cells: 38.5;Hofbauer cells: 43.1;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1345.3;non-classical monocyte: 1608.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 908.5;SK-MEL-30: 1012.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 49000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 100.7 67.9 40.3 185.6 44.4 70.5 65.4 40.1 45.5 35.9 45.2 67.8 44.8 39.6 70.3 54.4 50.8 48.7 157.6 44.2 56.0 83.6 47.9 207.5 139.0 72.0 52.6 21.2 47.5 39.2 63.4 324.4 65.3 49.1 72.0 37.8 49.5 38.3 74.7 28.4 67.7 76.2 47.6 110.6 70.1 67.7 55.0 61.7 159.9 67.0 86.2 107.7 30.7 44.9 91.2 85.7 54.6 319.1 78.7 110.7 87.3 117.4 220.7 232.1 301.4 57.4 80.2 101.7 105.5 277.4 59.7 151.1 158.8 130.3 153.1 154.4 48.3 64.1 60.9 72.3 908.5 184.9 101.6 126.9 186.9 141.3 290.1 74.5 225.0 66.1 202.8 255.0 107.5 178.0 64.3 87.1 55.4 94.1 152.2 51.4 86.5 64.9 119.3 80.8 145.7 84.9 69.4 58.7 1012.4 70.5 153.6 234.7 153.1 25.7 58.9 269.2 61.3 446.4 277.1 191.9 295.0 144.2 205.5 96.5 471.7 610.4 41.5 1345.3 38.4 71.4 34.5 38.4 337.9 68.0 24.8 28.6 170.9 44.5 1608.2 54.7 44.8 672.7 40.3 44.4 40.1 45.5 44.2 56.0 72.0 52.6 65.3 47.6 55.0 44.9 66.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 16.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 11.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 0.0 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Cell line enhanced" "Detected in some" "Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 10.2 5.2 6.3 52.2 5.8 58.4 4.4 5.9 8.1 3.3 6.3 6.4 8.0 2.8 3.0 3.5 5.6 6.9 3.5 6.0 8.0 4.4 7.2 19.1 54.2 11.1 8.2 1.8 2.4 1.4 2.9 9.0 8.6 4.2 5.0 0.4 4.9 2.8 1.4 2.8 23.0 6.1 8.0 83.0 7.0 1.9 8.6 42.0 3.5 3.4 36.2 10.3 3.0 10.8 0.8 0.2 0.4 1.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.9 76.5 0.3 0.0 0.3 2.0 0.3 0.2 0.0 44.2 0.4 67.6 0.9 0.0 0.8 34.9 157.0 0.3 0.1 0.1 0.0 0.0 0.0 40.3 0.7 45.7 0.0 7.6 70.8 75.7 0.4 1.1 0.4 61.1 0.3 94.0 0.1 0.0 0.5 0.9 1.0 0.7 0.5 0.2 0.4 68.8 0.5 0.1 0.4 1.2 0.1 83.1 43.6 53.7 0.5 87.4 0.2 3.3 7.6 37.4 4.6 8.4 3.4 3.0 3.5 3.9 5.7 3.3 3.1 3.5 29.2 3.6 9.5 3.1 5.4 4.0 6.3 5.8 5.9 8.1 6.0 8.0 11.1 8.2 8.6 8.0 8.6 10.8 1.5 3.2 14.3 0.7 83.2 2.4 0.2 0.2 2.2 0.2 1.1 1.8 1.1 0.0 0.1 0.0 0.0 0.9 91.7 0.3 1.9 0.4 0.6 0.4 0.4 2.6 1.2 14.1 0.3 0.4 1.1 1.5 5.6 0.3 48.1 0.2 3.9 1.6 111.5 0.0 0.3 0.2 0.0 110.7 54.5 1.1 0.0 118.1 3.6 4.7 88.2 0.2 84.5 0.5 0.0 0.1 0.1 0.0 57.8 0.2 0.1 1.8 1.6 0.2 0.0 1.0 1.3 1.3 1.1 0.8 1.4 1.4 99.3 0.4 0.1 0.2 WASF3 "KIAA0900, SCAR3, WAVE3" ENSG00000132970 "WASP family member 3" Q9UPY6 13 26557683-26688948 "Cancer-related genes, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.0;retina: 56.4" "Cell type enhanced" "Detected in many" "Astrocytes: 161.6;Early spermatids: 104.1;Horizontal cells: 82.4;Inhibitory neurons: 127.5;Oligodendrocyte precursor cells: 69.9" "Cancer enhanced" "Detected in all" "glioma: 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037086, HPA066228" Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "CAB037086: AB_1080585, HPA066228: " "unprognostic (1.42e-1)" "unprognostic (3.65e-2)" "unprognostic (2.25e-1)" "unprognostic (7.57e-2)" "unprognostic (8.23e-2)" "unprognostic (3.34e-1)" "unprognostic (6.19e-2)" "unprognostic (8.37e-2)" "unprognostic (8.98e-2)" "unprognostic (2.99e-1)" "prognostic favorable (2.21e-4)" "unprognostic (8.86e-3)" "unprognostic (2.93e-3)" "unprognostic (6.35e-2)" "unprognostic (2.12e-2)" "unprognostic (2.69e-3)" "unprognostic (9.18e-2)" 19.6 15.9 49.6 2.8 52.4 0.3 14.7 60.0 50.0 9.3 2.6 7.4 1.0 9.1 4.9 3.9 11.2 4.0 8.7 48.9 48.1 6.9 6.9 7.4 2.6 40.2 51.1 20.9 5.2 6.7 8.6 0.5 31.3 9.0 3.1 56.4 6.1 9.3 7.8 4.7 3.8 7.6 28.8 5.1 7.2 13.0 50.3 1.6 17.0 5.0 1.7 7.4 7.6 45.2 0.0 0.2 39.4 0.1 82.8 16.4 3.6 17.6 24.7 26.4 11.7 0.0 3.7 15.3 2.1 39.5 10.2 3.6 10.7 11.4 20.7 0.0 9.9 1.0 0.0 15.0 12.3 5.8 11.2 33.7 10.7 5.6 17.1 5.4 35.2 5.0 0.5 0.1 8.3 3.2 0.0 0.2 10.5 0.6 3.8 0.0 21.5 0.1 2.9 7.3 9.2 18.9 8.6 7.4 11.5 8.4 0.0 0.6 20.1 19.3 7.4 10.1 9.1 0.0 0.0 15.1 9.3 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 52.4 60.0 50.0 48.9 48.1 40.2 51.1 31.3 28.8 50.3 45.2 11.2 25.6 2.0 161.6 0.2 2.2 2.8 1.7 2.8 46.2 4.9 6.5 9.8 4.3 1.9 9.2 33.3 0.1 0.3 0.9 11.7 2.3 104.1 1.3 4.6 8.3 20.4 0.0 49.4 2.7 0.3 15.7 2.0 2.3 14.7 62.8 12.5 8.2 0.3 82.4 127.5 1.3 0.0 1.9 2.7 35.3 14.6 4.3 5.4 30.9 0.7 46.7 1.0 69.9 41.0 2.0 0.0 29.0 0.1 5.1 0.0 3.3 1.2 41.2 6.6 32.0 9.1 7.2 18.7 2.0 1.4 0.0 0.2 5.1 0.5 1.9 WASHC5 "KIAA0196, SPG8" ENSG00000164961 "WASH complex subunit 5" Q12768 8 125024260-125091819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.8;Exocrine glandular cells: 17.2;Hofbauer cells: 21.8;Proximal tubular cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034216, CAB034219, HPA064649, HPA070916" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB034216: AB_2234159, CAB034219: AB_2130519, HPA064649: AB_2685312, HPA070916: AB_2686322" "unprognostic (1.98e-3)" "unprognostic (3.75e-2)" "unprognostic (8.40e-2)" "unprognostic (3.89e-3)" "unprognostic (2.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (2.54e-2)" "unprognostic (3.54e-1)" "unprognostic (5.69e-2)" "unprognostic (9.10e-3)" "unprognostic (1.53e-1)" "unprognostic (9.39e-3)" "unprognostic (5.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" 18.1 18.6 10.5 18.5 16.9 21.3 19.6 14.9 13.2 17.2 16.5 18.5 18.1 16.2 15.7 16.6 13.3 17.8 16.1 11.1 12.5 22.9 18.5 17.1 19.6 14.7 13.7 15.6 13.0 24.8 9.5 21.2 14.6 17.4 20.1 11.4 14.3 16.1 15.9 13.6 14.7 20.2 14.0 19.3 16.1 9.5 13.8 21.8 23.3 18.5 21.0 21.1 10.3 24.7 40.0 45.4 24.9 30.6 55.3 58.8 16.3 42.0 63.6 43.0 45.8 17.0 42.1 36.1 29.1 54.1 25.3 30.6 40.2 37.7 56.8 47.5 23.1 48.1 26.5 22.8 53.8 14.8 46.6 58.7 25.1 35.5 31.2 33.2 49.9 30.9 28.3 35.6 53.0 87.6 44.3 11.8 23.7 66.7 46.7 29.8 22.4 36.7 33.2 48.5 13.1 26.3 48.8 109.2 39.5 25.8 47.3 25.5 44.7 23.6 51.9 39.4 37.7 31.7 31.2 31.7 62.4 27.5 33.4 10.4 17.0 12.5 13.5 20.9 14.3 9.5 12.8 13.9 19.7 10.6 10.1 14.3 5.8 17.2 29.3 7.2 16.9 13.0 10.5 16.9 14.9 13.2 11.1 12.5 14.7 13.7 14.6 14.0 13.8 24.7 10.9 3.2 19.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 14.4 9.3 0.0 0.0 5.0 11.0 0.0 13.4 6.9 0.0 5.9 12.2 0.0 9.9 13.5 4.9 0.0 0.0 0.0 17.2 11.0 5.4 0.0 14.8 8.8 11.1 0.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 16.2 0.0 0.0 1.9 0.0 0.0 17.2 4.4 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 12.3 3.8 9.6 0.0 0.0 WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2736.1" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.2;LHCN-M2: 1.0;NTERA-2: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" 1.3 2.7 22.4 0.3 34.3 0.0 22.9 16.3 44.6 1.6 15.0 0.3 0.0 8.6 23.8 4.7 1.5 0.0 0.5 24.8 35.4 0.7 0.0 117.4 0.1 16.6 16.5 1.2 0.3 0.0 46.5 0.0 16.2 14.2 0.3 599.7 45.1 2.8 0.1 6.6 2.2 0.9 16.5 0.1 1.4 0.7 23.4 0.2 0.0 0.7 0.0 1.7 2.2 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 34.3 16.3 44.6 24.8 35.4 16.6 16.5 16.2 16.5 23.4 18.4 0.0 35.3 197.8 186.1 0.0 12.6 34.5 0.0 2.2 25.0 0.7 13.7 1.6 0.0 26.6 1.8 8.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 4.7 0.0 0.0 0.6 0.0 0.0 27.8 0.5 0.1 7.6 1.0 0.0 0.0 0.0 15.2 46.5 0.0 0.0 0.0 20.4 0.0 0.0 0.8 23.2 12.2 0.0 2736.1 0.0 1.5 0.9 0.0 0.0 0.4 0.2 25.5 0.0 1.2 34.2 80.8 0.0 1.8 1.5 2.5 2.0 0.4 10.5 0.0 1.2 0.0 0.0 0.8 WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917066 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;ovary: 41.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.1;Granulosa cells: 149.4;Leydig cells: 50.7;Peritubular cells: 100.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 22.1;cerebral cortex: 49.9;hippocampal formation: 40.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.1;HEK 293: 4.1;K-562: 6.6;NTERA-2: 5.1;RPMI-8226: 11.3;SK-MEL-30: 4.5" "Region enhanced" "Detected in all" "hippocampal formation: 213.9" "Region enhanced" "Detected in all" "hippocampal formation: 156.3" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041145: AB_10795001, HPA041211: AB_10795003" "prognostic favorable (7.93e-4)" "unprognostic (1.35e-1)" "unprognostic (1.37e-3)" "unprognostic (2.12e-3)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (8.95e-3)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-2)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "unprognostic (3.33e-2)" "unprognostic (1.41e-1)" 1.0 5.6 8.7 1.0 22.1 0.5 1.1 0.0 49.9 0.4 0.0 0.7 2.9 3.3 19.7 1.2 8.8 1.4 4.0 40.3 4.2 2.5 0.5 0.5 0.7 0.4 2.6 41.7 1.7 1.2 0.9 0.2 0.1 4.4 0.5 3.8 4.0 4.8 25.0 0.9 2.6 4.1 0.5 1.0 5.9 18.8 7.4 0.4 2.0 8.8 0.7 1.4 0.2 8.1 0.3 1.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 18.1 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.1 0.0 0.1 0.0 0.0 5.1 0.0 3.6 0.0 0.0 11.3 0.0 0.0 1.8 1.5 0.1 0.1 4.5 2.4 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.1 0.0 8.7 22.1 0.0 49.9 40.3 4.2 0.4 2.6 0.1 0.5 7.4 8.1 1.5 0.0 0.0 6.2 0.0 2.2 1.5 0.6 1.2 8.2 4.9 4.6 9.3 0.0 1.4 3.7 2.1 0.0 0.3 0.5 3.9 3.8 1.8 5.0 0.4 4.1 1.8 3.0 45.1 3.5 0.1 7.3 11.7 1.2 0.0 149.4 0.4 0.5 4.5 5.0 27.0 0.7 0.0 0.0 1.0 4.8 50.7 1.0 5.4 1.9 0.0 6.2 0.0 2.0 1.9 2.4 1.5 100.4 0.1 1.1 5.5 5.5 5.1 2.9 6.6 7.2 16.0 4.4 9.9 0.9 0.4 0.0 1.0 8.7 2.0 0.4 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0;kidney: 37.6;prostate: 11.6" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 160.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 32.6;K-562: 36.8;TIME: 34.1;WM-115: 23.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.3 0.0 0.7 1.1 0.9 0.0 2.8 0.8 3.3 0.6 0.3 9.8 1.9 0.2 0.7 8.9 0.4 0.0 0.1 1.7 1.1 37.6 0.2 0.1 0.1 1.1 0.7 4.3 0.2 0.0 1.2 0.0 0.7 11.6 11.0 0.6 1.8 1.1 0.0 0.5 3.7 0.4 0.6 0.1 3.4 0.2 1.0 0.0 0.0 0.3 0.1 0.2 0.4 1.0 2.1 1.2 0.6 0.0 0.7 0.2 4.8 11.9 4.8 4.5 1.3 0.7 1.0 0.6 6.8 32.6 1.2 0.0 0.2 0.3 8.6 0.6 1.8 0.1 0.0 4.7 7.4 0.3 0.7 3.9 1.4 6.4 2.1 2.1 0.3 0.4 36.8 1.3 0.0 1.0 0.0 1.1 0.3 2.0 8.2 0.6 1.2 0.0 0.0 0.5 0.0 0.2 0.1 0.2 1.7 4.1 2.4 2.7 34.1 0.3 3.1 0.5 0.4 6.2 5.3 1.2 0.0 2.1 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.8 3.3 1.7 1.1 1.1 0.7 0.7 0.6 1.0 1.0 0.2 0.0 0.6 0.0 0.5 0.0 0.2 0.0 0.6 0.2 7.1 4.1 1.0 1.5 0.6 7.3 0.0 0.0 0.3 8.0 160.4 0.0 0.0 5.1 1.1 0.2 13.1 0.0 0.2 0.2 0.2 0.1 3.1 6.7 4.5 0.1 0.7 0.0 0.0 0.0 0.2 40.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.2 0.4 0.0 3.6 0.9 1.0 2.9 0.5 0.0 0.2 0.5 0.8 0.8 12.1 0.4 0.0 0.2 0.0 13.1 0.3 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WSB2 "MGC10210, SBA2" ENSG00000176871 "WD repeat and SOCS box containing 2" Q9NYS7 12 118032687-118062430 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052606 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052606: AB_2681882" "unprognostic (5.02e-3)" "unprognostic (4.57e-2)" "unprognostic (4.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.42e-3)" "unprognostic (4.66e-3)" "unprognostic (7.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.93e-1)" "unprognostic (4.05e-1)" "unprognostic (2.92e-1)" "unprognostic (2.66e-1)" "unprognostic (2.79e-1)" "unprognostic (2.42e-2)" 33.8 46.8 94.4 29.8 102.1 17.6 20.2 85.2 117.5 19.6 53.2 44.7 35.3 18.7 23.8 53.0 17.9 25.3 55.8 103.0 83.8 35.5 36.6 31.5 24.1 100.3 106.3 13.8 36.7 43.0 36.1 19.2 96.4 26.6 45.3 38.9 20.9 26.4 102.7 23.0 39.0 35.7 95.2 17.7 33.0 18.6 99.4 20.8 46.5 163.3 28.3 45.6 21.1 95.4 49.3 78.2 55.2 93.5 81.1 46.7 39.1 129.3 95.9 138.6 82.8 41.5 66.4 7.1 42.6 168.7 77.4 25.8 46.6 78.6 98.7 90.7 29.6 27.5 36.7 39.0 85.7 16.2 71.5 62.7 77.7 75.0 51.6 148.7 72.3 48.5 83.2 12.5 143.8 73.2 10.3 9.9 32.2 110.7 48.2 29.3 57.5 2.2 81.9 211.5 58.5 87.3 100.1 21.8 69.9 54.7 75.0 37.3 113.7 164.6 68.7 53.1 158.8 21.6 14.6 13.4 148.8 20.3 266.9 9.7 5.0 11.5 4.5 7.5 4.0 0.7 4.4 4.7 3.5 1.8 1.9 3.4 5.4 3.4 5.2 4.1 5.1 1.8 94.4 102.1 85.2 117.5 103.0 83.8 100.3 106.3 96.4 95.2 99.4 95.4 17.1 25.6 15.7 14.7 5.9 16.6 39.4 16.4 5.2 21.0 20.2 10.3 33.7 24.3 14.1 20.2 4.2 10.0 11.8 75.1 21.5 37.4 2.0 19.5 23.6 16.7 72.7 7.4 45.9 85.1 24.3 19.6 23.0 31.5 7.0 13.1 17.2 36.4 34.7 57.2 31.9 40.7 22.4 51.8 18.4 4.7 7.5 23.5 28.4 18.7 34.8 34.1 11.3 18.1 30.7 89.6 44.5 17.3 6.2 53.4 47.7 35.6 7.2 14.1 13.1 21.8 26.0 3.2 5.1 17.8 18.6 17.2 13.1 44.8 25.8 86.9 XAGE3 "CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3" ENSG00000171402 "X antigen family member 3" Q8WTP9 X 52862525-52868083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 121 "placenta: 382.1" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 2223.5;Extravillous trophoblasts: 1309.1;Syncytiotrophoblasts: 2678.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;U-266/70: 2.2;U-266/84: 2.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 29: U-266 - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (6.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.92e-1)" 3.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 382.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2223.5 0.0 0.1 0.0 0.2 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.4 1309.1 11.1 0.0 0.3 0.0 0.0 0.0 4.6 191.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 15.1 7.0 0.0 0.0 2678.1 0.0 0.0 0.1 0.0 XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1159.0" "Cell type enhanced" "Detected in all" "Breast glandular cells: 1756.7;Plasma cells: 2344.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 960.5;SK-BR-3: 870.0;T-47d: 1012.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" 100.3 103.7 23.8 150.1 25.9 247.2 720.6 26.8 27.7 369.7 46.8 203.6 163.7 94.2 150.5 85.2 126.5 120.2 75.8 22.5 32.2 87.7 687.3 151.8 138.3 33.3 33.2 67.5 1159.0 195.1 87.7 107.9 29.0 228.8 196.5 21.1 849.4 152.1 90.1 72.2 140.3 105.5 30.8 213.2 259.9 22.2 33.0 148.2 168.9 48.7 307.8 250.4 52.2 30.8 77.1 50.8 71.4 111.0 132.2 144.2 181.1 130.9 223.2 128.4 168.8 82.5 104.4 290.2 63.0 121.8 75.3 104.5 134.2 64.4 110.4 130.0 84.9 88.3 42.6 356.2 285.9 166.1 80.8 90.7 378.2 85.2 363.7 115.9 104.1 35.0 79.5 355.0 78.6 960.5 23.3 157.0 49.7 594.6 79.0 168.6 78.5 401.5 118.4 105.4 94.7 90.7 79.0 870.0 358.6 94.8 1012.9 188.5 59.8 73.3 69.8 78.5 47.3 598.8 456.8 174.8 98.0 210.0 112.3 185.0 27.1 23.5 73.3 14.1 95.2 38.0 52.4 76.5 23.5 43.8 52.9 43.2 2.1 88.5 10.1 75.0 20.5 38.5 23.8 25.9 26.8 27.7 22.5 32.2 33.3 33.2 29.0 30.8 33.0 30.8 116.4 86.6 195.6 3.6 379.0 210.6 410.2 192.2 47.3 25.4 1756.7 829.4 46.2 205.9 390.1 138.0 131.3 112.8 298.6 171.2 80.3 240.6 30.2 160.1 147.8 107.0 189.7 68.6 8.5 633.3 335.4 220.0 208.0 293.6 99.7 55.1 93.1 654.5 267.9 15.2 11.4 633.0 225.9 130.0 281.5 22.7 95.7 172.3 355.8 18.7 95.0 18.6 385.2 8.0 7.3 328.4 190.5 64.7 2344.9 381.9 247.0 73.2 168.9 53.2 13.1 144.4 179.3 36.8 32.5 86.2 202.0 349.7 206.1 34.8 260.0 355.3 XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.4" "Group enriched" "Detected in many" 10 "dendritic cells: 513.6;NK-cells: 277.1;T-cells: 240.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 423.5" "Lineage enriched" "Detected in many" 8 "NK-cells: 423.5" "Cell line enhanced" "Detected in some" "CACO-2: 3.0;RT4: 1.1;SuSa: 1.1" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" 1.1 0.8 0.3 3.2 0.3 14.1 0.9 0.3 0.5 1.0 0.4 1.9 3.2 3.6 0.9 0.6 1.8 1.9 0.7 0.3 0.4 0.4 5.6 3.3 5.6 0.5 0.3 0.4 0.6 0.3 0.2 1.4 0.4 0.5 1.5 0.0 1.9 1.0 0.3 0.1 2.0 1.4 0.4 13.4 2.9 0.3 0.6 3.8 0.6 0.5 3.6 2.0 0.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.4 47.2 0.2 2.7 0.3 3.6 50.1 0.3 0.1 2.1 37.1 1.9 423.5 0.3 0.1 0.0 17.1 0.3 0.3 0.3 0.5 0.3 0.4 0.5 0.3 0.4 0.4 0.6 0.4 2.9 0.0 1.1 0.0 3.3 2.4 0.0 0.0 1.8 0.0 1.6 1.4 0.8 0.0 0.0 0.0 0.0 0.1 513.6 0.3 0.0 0.1 0.0 2.4 2.0 1.0 0.0 19.2 0.0 0.0 0.0 1.1 8.2 2.2 1.3 0.0 1.4 0.6 0.4 0.0 0.0 0.7 0.0 5.0 4.0 0.0 0.0 3.7 33.8 0.0 0.8 0.0 277.1 0.0 0.0 0.0 1.1 0.0 13.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.9 1.1 0.0 240.6 0.0 0.1 0.1 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "ASC diff: 55.1;ASC TERT1: 34.0;U-2197: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA 150000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 6.4 6.2 6.2 4.9 8.0 7.2 4.5 2.3 6.3 7.8 8.5 8.8 4.3 7.9 1.0 5.1 3.7 2.3 4.2 8.8 3.6 1.0 0.3 3.5 5.1 3.7 4.3 5.3 2.8 0.9 0.6 6.0 4.2 2.7 5.2 8.3 2.5 4.5 1.1 5.0 5.3 5.7 1.6 5.4 3.4 2.3 3.6 4.1 2.2 1.2 4.3 4.3 4.6 4.6 0.0 0.3 8.0 0.1 55.1 34.0 9.6 25.6 12.9 2.7 1.0 0.3 0.6 6.1 0.0 31.3 0.9 0.6 0.0 5.1 4.5 12.1 0.6 8.0 0.0 0.0 0.6 11.5 10.2 12.6 0.7 15.0 2.4 4.6 0.0 0.3 0.0 23.8 2.8 0.8 0.1 12.4 8.5 4.4 0.0 3.5 0.0 1.2 0.0 11.5 2.0 15.2 1.9 7.9 1.4 5.9 1.9 7.2 0.0 24.6 2.9 57.2 0.0 26.4 1.4 11.6 28.9 12.8 22.4 0.3 0.2 0.4 0.2 1.2 0.3 0.1 0.1 0.1 0.4 0.3 0.2 0.1 0.1 0.4 2.0 0.1 0.3 0.2 6.2 8.0 2.3 6.3 8.8 3.6 3.7 4.3 4.2 1.6 3.6 4.6 1.0 3.2 2.5 45.4 9.2 7.9 1.6 0.0 1.2 12.9 3.8 3.7 3.4 0.0 0.7 0.0 98.0 12.7 12.4 9.1 0.0 1.5 0.5 0.5 24.7 2.9 12.6 7.4 172.8 1.6 20.1 12.2 2.6 0.8 2.5 6.4 1.4 0.2 3.5 0.0 72.8 4.3 4.1 9.7 27.6 0.8 12.8 8.5 3.6 29.0 6.1 1.9 11.3 1194.8 63.0 4.0 7.4 50.0 6.2 5.3 6.1 0.2 0.0 4.4 6.6 7.9 5.9 0.3 1.6 4.1 18.5 13.1 7.7 8.1 6.9 6.4 YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Syncytiotrophoblasts: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: AB_1847686, HPA073931: " "unprognostic (4.94e-2)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.06e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.96e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.38e-1)" "unprognostic (5.39e-3)" "unprognostic (6.35e-1)" 7.1 9.2 5.3 6.2 5.6 5.7 8.5 5.8 15.2 6.7 6.9 7.9 6.9 4.1 7.6 9.0 6.3 5.5 6.6 5.9 6.3 11.1 13.5 7.7 7.1 6.7 5.8 7.0 6.8 7.0 6.2 9.7 6.8 11.3 9.2 7.2 11.7 4.8 14.6 9.4 6.9 6.0 6.2 8.2 8.7 7.2 6.0 8.8 22.1 10.4 10.7 7.7 7.1 6.4 11.0 6.4 10.1 7.1 11.9 13.1 9.0 7.7 12.0 14.0 18.3 7.1 3.3 3.8 12.9 9.2 21.6 13.2 12.9 17.0 14.4 27.4 10.3 8.9 6.4 11.6 15.9 10.0 8.1 13.3 15.8 11.3 13.5 12.0 15.0 13.2 9.6 10.0 14.0 9.2 10.8 14.2 7.7 12.7 10.4 6.6 9.3 15.4 11.5 5.8 4.5 5.6 7.4 13.8 35.4 31.0 21.4 11.1 7.1 5.7 5.8 10.4 6.8 20.1 24.7 7.0 9.3 8.1 5.0 19.1 18.4 20.2 11.8 16.5 11.0 10.4 10.0 12.1 16.6 13.8 9.5 9.2 38.3 11.0 23.3 11.5 24.3 16.5 5.3 5.6 5.8 15.2 5.9 6.3 6.7 5.8 6.8 6.2 6.0 6.4 11.6 6.4 12.6 9.8 9.0 8.5 17.6 19.2 9.6 6.6 20.0 12.4 9.6 24.3 24.0 9.2 0.0 80.0 8.5 14.6 11.7 28.3 30.5 11.4 10.9 10.9 9.6 12.2 9.8 32.6 28.4 9.9 9.7 14.7 9.5 6.3 11.7 20.8 39.7 10.1 8.2 27.5 30.5 19.4 7.7 54.9 5.9 18.9 10.6 11.2 20.2 16.5 21.6 8.5 11.5 32.5 10.8 9.4 28.1 33.2 12.3 17.7 19.7 6.5 0.0 5.6 17.7 22.2 20.9 12.3 10.9 129.6 10.8 17.7 10.8 29.0 YWHAG "14-3-3γ, 14-3-3GAMMA, PPP1R170" ENSG00000170027 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma" P61981 7 76326799-76358991 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 337.4;skeletal muscle: 349.8" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 408.8;Suprabasal keratinocytes: 425.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013274, CAB018389, HPA026918" Approved Approved Approved Cytosol NA NA 66000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB013274: , CAB018389: AB_2217962, HPA026918: AB_10610566" "unprognostic (3.71e-2)" "prognostic unfavorable (4.53e-4)" "unprognostic (3.88e-2)" "unprognostic (1.25e-2)" "unprognostic (6.28e-3)" "unprognostic (2.40e-3)" "unprognostic (8.98e-3)" "prognostic unfavorable (5.34e-4)" "unprognostic (1.63e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.03e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (9.31e-2)" "unprognostic (1.51e-1)" "unprognostic (2.45e-2)" "unprognostic (1.70e-1)" 188.1 99.2 165.6 60.6 185.3 27.3 61.0 80.2 337.4 41.1 8.5 48.4 47.8 50.9 20.8 64.5 37.9 54.5 111.4 206.5 206.1 50.8 72.4 47.1 43.2 204.5 120.7 40.7 59.7 50.1 32.6 55.4 192.9 46.1 44.0 87.2 39.9 40.0 349.8 43.7 41.6 66.4 81.5 44.2 38.2 28.9 135.1 40.2 29.7 238.4 48.6 78.8 46.3 199.1 189.0 231.9 200.5 256.7 200.5 114.9 90.5 213.3 105.0 129.6 139.5 147.0 196.7 263.5 71.7 190.8 215.2 171.6 254.3 235.8 180.5 179.9 110.9 250.2 150.0 164.5 182.6 309.0 234.0 127.1 221.0 151.5 310.8 137.3 208.9 140.2 349.9 289.0 195.8 177.6 222.3 227.1 223.0 150.7 160.4 256.3 203.0 291.7 204.5 126.3 107.0 297.1 236.7 299.2 156.0 256.9 208.5 184.2 222.6 250.7 145.7 225.4 290.1 95.1 191.6 399.5 225.5 285.3 273.8 1.5 2.3 0.5 0.8 2.0 1.4 1.3 1.0 1.1 2.4 0.7 0.7 0.9 0.5 0.5 1.8 2.6 0.9 0.9 165.6 185.3 80.2 337.4 206.5 206.1 204.5 120.7 192.9 81.5 135.1 199.1 73.7 32.1 26.4 23.2 51.8 408.8 128.3 87.9 126.9 102.9 107.0 70.1 234.0 40.0 55.1 38.6 12.5 36.5 39.3 49.9 37.2 52.4 91.2 96.0 82.9 92.0 85.4 72.8 99.9 38.2 84.1 97.4 61.2 127.9 67.3 38.7 50.0 93.1 83.5 124.5 78.5 35.7 44.7 90.3 229.0 25.2 46.3 87.8 94.3 40.3 64.2 27.1 20.6 23.1 57.1 71.1 29.9 43.2 56.6 129.8 34.1 61.3 47.2 35.3 32.9 92.5 91.5 13.4 19.0 160.1 425.4 67.2 41.5 46.4 45.1 177.1 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 79.9" "Group enriched" "Detected in many" 4 "dendritic cells: 101.0;NK-cells: 155.5;T-cells: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 41 "gdT-cell: 137.4;MAIT T-cell: 93.2;memory CD4 T-cell: 71.7;memory CD8 T-cell: 108.3;naive CD4 T-cell: 50.8;naive CD8 T-cell: 79.8;NK-cell: 112.2;T-reg: 80.1" "Group enriched" "Detected in many" 56 "NK-cells: 112.2;T-cells: 137.4" "Group enriched" "Detected in some" 11 "JURKAT: 121.0;MOLT-4: 183.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 14000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 3.3 1.3 0.5 28.0 0.6 24.8 1.9 0.5 0.9 1.7 0.7 4.0 5.8 1.4 0.5 2.3 2.2 5.4 1.4 0.5 0.7 2.8 3.9 8.7 57.0 0.8 1.3 0.8 1.0 0.4 1.1 0.9 0.7 2.5 1.5 0.0 2.3 0.8 2.0 2.4 18.5 0.5 0.6 35.5 6.7 2.7 1.2 79.9 3.5 2.8 17.7 4.9 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 121.0 0.0 0.7 0.0 0.0 183.4 0.5 0.1 0.0 0.0 7.2 0.1 9.1 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 14.1 0.1 0.0 0.0 0.3 0.3 0.5 137.4 0.4 93.2 0.2 71.7 108.3 0.3 1.6 50.8 79.8 2.2 112.2 1.0 0.9 80.1 64.2 0.5 0.6 0.5 0.9 0.5 0.7 0.8 1.3 0.7 0.6 1.2 0.6 0.8 9.6 13.6 0.3 3.9 1.5 0.0 0.0 0.0 0.0 0.8 0.5 3.0 0.0 0.0 0.0 0.0 0.1 101.0 0.2 1.9 0.2 1.0 1.6 0.5 0.8 0.0 8.8 0.2 0.0 0.0 1.8 4.6 0.4 2.5 0.1 2.5 0.7 2.2 0.0 0.2 0.0 0.0 2.8 2.2 0.7 0.0 3.4 1.8 2.8 5.0 0.0 155.5 0.0 0.1 0.0 0.0 0.0 28.0 0.1 0.0 0.5 0.0 0.0 0.0 14.3 0.6 1.3 2.1 0.2 1.4 0.0 105.6 0.1 0.1 0.2 ZBED3 MGC15435 ENSG00000132846 "Zinc finger BED-type containing 3" Q96IU2 5 77072072-77087285 "Predicted intracellular proteins, Predicted secreted proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.7;JURKAT: 31.0;MOLT-4: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055995 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA055995: AB_2683000" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.45e-2)" "unprognostic (6.96e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "unprognostic (3.63e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.08e-1)" "unprognostic (1.92e-1)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" 10.3 3.3 9.3 1.9 14.2 2.6 8.8 9.4 10.8 6.7 7.5 4.2 3.9 10.2 7.4 2.4 7.0 3.5 4.6 7.8 9.2 10.0 10.7 5.0 1.9 16.0 12.2 7.9 7.6 8.4 3.9 2.4 10.9 5.1 4.3 3.8 6.0 6.6 2.7 2.6 3.3 8.7 9.9 3.6 6.4 1.9 13.5 4.8 11.2 3.8 1.9 3.0 3.7 17.1 5.2 4.2 5.4 29.7 22.1 1.5 0.3 1.7 5.0 2.6 6.9 9.1 2.4 0.0 10.9 3.4 1.1 0.6 2.9 1.8 2.3 1.7 5.8 4.0 9.1 10.4 13.1 5.5 1.5 24.6 6.8 1.3 5.1 4.2 8.3 31.0 0.0 11.0 1.6 5.2 29.4 0.8 3.5 1.4 2.5 12.1 10.3 1.7 12.3 2.0 5.9 12.4 6.1 5.0 8.7 2.1 7.5 3.8 3.3 2.3 4.5 5.1 7.0 8.0 8.2 11.5 3.6 10.4 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 9.3 14.2 9.4 10.8 7.8 9.2 16.0 12.2 10.9 9.9 13.5 17.1 10.5 0.0 2.8 8.1 1.7 1.3 3.8 0.3 4.0 8.4 13.5 13.6 10.7 12.8 2.0 12.9 12.5 1.5 2.0 3.1 17.6 4.1 3.3 16.5 13.5 11.7 16.2 5.0 3.3 6.0 0.3 9.3 11.7 12.5 1.3 20.2 12.1 31.8 9.6 3.3 8.5 5.3 0.0 13.6 4.9 2.2 17.7 9.0 7.2 5.6 5.1 13.8 3.1 16.1 18.3 2.7 3.4 11.3 1.4 5.6 1.9 17.2 0.1 17.0 0.0 21.4 7.7 1.5 3.4 2.2 1.4 0.3 1.2 25.6 7.1 1.8 ZBTB32 "FAXF, FAZF, Rog, TZFP, ZNF538" ENSG00000011590 "Zinc finger and BTB domain containing 32" Q9Y2Y4 19 35704558-35717038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 49.0" "Cell type enhanced" "Detected in some" "B-cells: 24.0;Early spermatids: 39.6;granulocytes: 17.7;Late spermatids: 73.0;Plasma cells: 25.6;Spermatocytes: 115.5" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "cerebellum: 1.4" "Immune cell enhanced" "Detected in some" "memory B-cell: 10.5" "Lineage enriched" "Detected in many" 5 "B-cells: 10.5" "Cell line enhanced" "Detected in some" "HDLM-2: 4.3;hTEC/SVTERT24-B: 2.0;U-266/70: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA076730 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA076730: AB_2732320" "unprognostic (2.11e-3)" "unprognostic (1.08e-4)" "unprognostic (3.87e-2)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.04e-5)" "unprognostic (2.59e-1)" "unprognostic (1.76e-1)" "unprognostic (2.16e-2)" "unprognostic (1.63e-3)" "unprognostic (1.01e-2)" "unprognostic (3.78e-1)" "unprognostic (1.02e-8)" "unprognostic (2.44e-3)" "unprognostic (2.25e-1)" "unprognostic (6.26e-5)" "unprognostic (1.94e-3)" 0.1 0.1 0.2 2.0 0.1 0.6 0.0 1.4 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.3 3.4 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.4 0.0 0.0 0.1 1.7 0.1 0.0 2.6 0.5 49.0 0.1 0.3 0.1 0.0 1.3 0.5 0.0 0.1 0.7 0.6 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.3 0.1 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 2.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.1 0.3 0.0 0.0 0.4 0.1 0.3 0.0 1.2 1.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 10.5 0.5 0.6 0.0 3.8 0.1 0.3 0.0 0.0 0.0 0.0 2.3 0.6 0.2 0.1 1.4 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 1.3 0.0 24.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 39.6 0.0 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.5 0.0 17.7 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 73.0 1.2 0.3 1.8 0.0 1.6 0.0 0.0 0.0 0.2 0.0 0.0 1.2 25.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 115.5 0.8 0.0 0.0 0.0 4.1 0.0 0.1 0.0 ZBTB7B "c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B" ENSG00000160685 "Zinc finger and BTB domain containing 7B" O15156 1 155002630-155018522 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.2;Proximal enterocytes: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006811, HPA025820" Enhanced Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA006811: AB_1859046, HPA025820: AB_1859045" "unprognostic (5.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-2)" "unprognostic (2.43e-1)" "unprognostic (4.95e-3)" "unprognostic (9.55e-2)" "unprognostic (1.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.46e-2)" "unprognostic (5.35e-2)" "unprognostic (1.11e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-2)" 24.9 35.3 12.9 18.1 15.8 30.0 27.9 15.8 12.9 25.3 11.7 55.4 61.9 16.1 6.4 95.4 17.9 11.0 25.2 11.2 13.6 19.7 48.4 25.0 16.2 18.3 17.5 12.7 29.9 15.6 20.0 9.0 17.3 30.5 18.6 6.5 40.2 12.8 40.6 111.9 71.2 9.9 15.8 31.6 37.7 6.1 17.7 9.0 25.5 17.6 15.2 20.4 44.4 17.9 16.5 29.0 2.5 8.8 12.7 7.2 34.7 11.1 13.1 11.4 13.2 19.5 23.4 7.2 19.5 12.6 9.1 24.5 8.1 15.7 2.4 39.4 9.1 12.0 51.4 13.1 18.6 9.2 31.7 9.4 54.8 15.6 19.3 15.3 9.1 1.1 17.3 32.2 6.7 31.2 0.2 20.7 8.7 26.4 23.8 6.8 1.9 45.6 17.2 16.9 16.1 16.5 21.4 56.5 8.9 10.6 35.2 30.7 7.7 7.4 12.9 14.8 9.5 38.1 25.1 7.6 17.3 30.3 8.6 0.4 1.5 1.3 0.6 1.4 0.2 0.6 0.7 0.3 0.9 0.7 0.6 0.2 2.3 0.7 1.2 0.0 1.0 2.5 12.9 15.8 15.8 12.9 11.2 13.6 18.3 17.5 17.3 15.8 17.7 17.9 6.5 9.6 0.0 11.1 8.5 35.2 9.3 8.8 29.6 13.6 35.2 15.6 2.6 18.6 7.1 5.5 2.1 11.9 6.9 135.2 11.7 13.3 4.3 15.4 6.7 5.6 6.7 6.1 1.0 15.1 14.6 4.9 27.5 21.3 5.7 2.8 6.1 29.9 14.8 16.8 1.1 32.7 14.2 28.7 40.3 8.3 9.0 20.7 16.0 4.7 25.8 5.4 11.3 0.0 8.6 16.8 57.7 7.2 6.8 24.9 158.5 10.0 4.2 10.3 0.0 3.2 5.7 0.5 1.2 51.7 53.6 27.5 11.3 4.4 38.5 24.4 ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type palmitoyltransferase 18" Q9NUE0 1 26826688-26857604 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 48.8" "Cell line enhanced" "Detected in all" "HDLM-2: 132.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040234 Approved Approved Microtubules NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 23.4 8.1 26.0 27.4 24.6 113.9 17.0 25.7 29.0 12.9 16.9 14.6 12.9 13.6 4.6 24.3 11.3 14.8 15.0 25.4 30.0 8.8 18.6 16.2 22.1 29.1 28.7 9.6 10.5 8.6 11.7 23.3 33.5 11.4 15.0 19.3 16.9 9.1 10.8 18.5 13.9 18.4 22.2 31.3 12.4 7.4 28.5 14.7 15.3 16.1 20.9 22.7 14.4 25.1 45.3 19.8 31.5 21.8 25.6 17.8 30.9 26.7 31.5 45.9 33.9 18.3 28.4 20.9 16.7 35.5 24.0 31.3 33.8 15.9 39.2 132.6 28.7 20.3 15.3 25.7 22.0 18.1 16.9 15.5 21.3 42.3 27.9 16.5 25.9 31.6 21.4 41.8 18.4 22.1 34.5 14.6 30.4 28.1 18.8 28.3 27.2 22.2 19.2 11.3 14.6 17.7 17.9 13.4 19.3 23.9 12.1 17.6 22.2 31.5 24.2 52.3 31.0 49.7 38.8 18.1 17.9 32.5 21.9 0.0 0.5 10.0 1.6 1.1 1.1 0.4 1.2 1.2 0.8 0.3 0.7 0.8 48.8 1.0 0.8 0.4 2.7 0.5 26.0 24.6 25.7 29.0 25.4 30.0 29.1 28.7 33.5 22.2 28.5 25.1 12.9 9.6 7.9 6.5 7.5 25.6 8.6 4.4 6.8 39.8 8.4 6.6 6.0 10.0 6.8 1.8 27.1 10.6 21.2 27.0 0.0 4.1 3.8 6.1 7.0 9.1 3.0 9.3 10.2 2.8 7.1 7.1 4.6 12.7 1.3 5.9 7.9 12.0 7.3 18.5 10.2 3.9 2.0 8.5 17.0 2.1 6.2 11.0 10.6 5.6 26.6 5.7 12.3 4.0 6.3 8.0 25.6 3.8 8.3 19.3 10.4 2.2 4.6 35.3 0.0 7.1 6.2 3.5 11.4 14.6 36.2 6.2 17.4 8.0 7.0 34.7 ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type palmitoyltransferase 3" Q9NYG2 3 44915257-44976185 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 8 "Early spermatids: 570.7;Late spermatids: 1564.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "CAB012465: , HPA016616: AB_1859004" "unprognostic (2.80e-1)" "unprognostic (6.07e-2)" "prognostic favorable (3.43e-4)" "unprognostic (3.10e-2)" "unprognostic (2.47e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.20e-2)" "unprognostic (1.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "prognostic favorable (1.81e-8)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-2)" 50.1 48.6 23.0 25.7 21.5 82.8 36.3 27.9 22.9 42.2 25.8 70.6 44.1 35.4 24.5 58.0 27.5 32.0 36.3 25.8 21.1 40.3 32.3 41.9 21.9 28.7 25.1 28.9 22.2 46.0 13.4 28.7 29.8 35.6 64.6 16.6 33.3 40.1 43.7 70.0 58.1 36.3 25.8 29.6 55.3 80.8 27.0 26.9 38.6 52.8 33.3 53.6 42.5 25.3 62.5 53.3 41.0 49.1 219.2 100.5 46.8 58.8 80.7 78.3 66.5 61.0 85.1 58.7 31.4 107.9 52.8 80.7 68.4 104.3 74.6 61.7 29.3 55.9 57.9 45.7 50.6 136.3 43.0 92.5 111.6 73.6 67.2 59.8 79.6 63.8 73.8 51.3 78.1 42.9 46.2 73.6 60.7 155.9 96.7 29.9 40.6 47.0 66.7 176.7 14.6 52.8 70.3 70.5 36.4 70.4 57.4 88.2 78.0 55.4 55.2 60.2 66.3 32.2 66.6 59.6 55.2 198.9 39.4 53.7 24.5 32.6 14.6 12.3 13.3 10.7 11.0 16.1 26.8 12.6 10.2 14.4 25.4 14.5 17.5 15.3 17.1 13.6 23.0 21.5 27.9 22.9 25.8 21.1 28.7 25.1 29.8 25.8 27.0 25.3 41.5 41.7 82.1 7.5 17.8 48.2 42.1 40.8 48.9 9.8 24.4 20.8 29.2 24.3 27.1 53.3 6.2 47.7 23.4 105.6 72.4 46.6 570.7 18.8 31.2 34.1 35.9 68.8 15.7 79.0 59.4 26.4 69.3 26.6 19.0 21.5 35.7 29.4 49.5 15.2 15.6 78.2 38.7 34.0 26.7 1564.3 51.9 37.4 24.9 18.7 35.6 25.1 34.0 15.1 11.2 115.8 73.1 44.8 26.2 73.7 112.9 30.1 20.9 10.6 19.7 15.6 31.9 104.5 45.3 70.5 60.2 101.7 25.0 26.1 72.8 128.9 ZDHHC7 "DHHC7, FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370" ENSG00000153786 "Zinc finger DHHC-type palmitoyltransferase 7" Q9NXF8 16 84974175-85011535 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019215, HPA059054, HPA059642" Uncertain Supported "Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "HPA019215: AB_2670102, HPA059054: AB_2683892, HPA059642: AB_2684093" "unprognostic (9.77e-2)" "unprognostic (2.12e-1)" "unprognostic (6.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (8.76e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.41e-2)" "unprognostic (5.78e-2)" "unprognostic (2.21e-2)" "unprognostic (7.79e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.12e-5)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.45e-1)" "unprognostic (5.42e-2)" 33.0 28.1 19.0 24.7 18.8 64.2 26.8 21.4 18.6 40.0 27.1 42.5 27.1 36.8 12.8 27.6 27.7 31.2 31.2 19.1 19.8 35.4 30.0 37.2 26.5 20.1 21.0 27.7 26.9 35.5 19.6 33.4 20.3 32.8 32.4 10.3 24.1 20.0 56.5 31.8 33.5 30.0 19.1 35.4 44.7 14.1 23.5 16.1 25.5 58.4 23.5 37.4 33.1 19.6 63.8 55.0 28.5 34.5 123.1 92.3 38.9 57.4 110.8 88.4 43.7 58.3 72.4 29.1 32.7 93.5 29.0 65.6 37.1 76.1 110.9 16.4 29.7 21.0 22.0 66.5 51.5 40.0 21.2 76.7 85.4 72.5 41.5 56.0 46.1 26.7 68.9 9.7 56.8 75.8 27.0 38.1 44.3 53.2 39.5 33.6 26.2 15.7 86.4 82.5 24.2 29.8 74.3 40.9 36.1 43.0 77.6 24.0 67.9 53.1 39.9 49.8 34.3 33.5 51.0 65.5 50.1 29.1 43.0 7.5 9.7 8.3 2.1 8.2 2.6 1.4 2.0 1.7 6.3 2.2 1.5 2.2 6.4 1.4 7.2 4.3 0.5 3.6 19.0 18.8 21.4 18.6 19.1 19.8 20.1 21.0 20.3 19.1 23.5 19.6 13.3 32.1 25.2 12.1 10.8 13.3 21.5 25.4 17.1 9.2 16.2 13.2 22.5 12.8 17.9 16.5 6.2 18.5 15.7 37.7 1.9 14.1 9.7 15.5 20.1 12.2 12.6 11.6 16.4 15.6 24.9 23.0 28.5 29.1 3.8 14.3 15.0 11.6 28.1 15.2 16.2 29.4 14.2 46.8 26.7 10.9 17.4 36.2 16.0 19.7 42.9 5.9 21.6 13.6 14.7 30.0 33.9 21.1 15.2 26.2 22.1 9.5 32.6 6.7 13.1 13.7 14.9 8.3 13.0 20.1 12.8 16.1 13.4 6.8 34.7 35.3 ZEB1 "AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a" ENSG00000148516 "Zinc finger E-box binding homeobox 1" P37275 10 31318495-31529814 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 287.8;Excitatory neurons: 276.1;Inhibitory neurons: 261.9;Microglial cells: 479.7;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 113.1;TIME: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027524, CAB058686, CAB079943" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Nucleoli "CAB058686: AB_2665569, CAB079943: , HPA027524: AB_1844977" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (4.85e-2)" "unprognostic (7.40e-2)" "unprognostic (1.34e-2)" "unprognostic (5.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.96e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (5.59e-3)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" "unprognostic (1.66e-2)" 26.6 8.6 16.4 12.9 16.2 8.6 16.8 14.0 20.1 33.2 9.9 49.2 6.0 38.7 13.4 11.7 18.6 20.0 34.8 15.2 22.8 7.5 10.4 16.0 9.6 21.1 19.2 9.3 3.8 3.4 7.9 17.5 21.2 14.5 12.3 14.8 8.0 26.9 54.4 7.0 11.8 39.9 16.8 8.1 18.1 10.1 18.2 29.9 11.2 60.5 9.7 24.4 16.4 18.5 0.1 11.1 35.1 43.9 58.4 113.1 0.0 32.7 44.9 6.6 9.3 0.2 0.1 11.3 15.6 39.6 9.3 0.0 14.9 0.0 11.8 19.1 7.9 0.0 7.0 6.3 44.4 9.8 0.3 53.4 0.1 19.6 17.6 21.4 54.9 9.5 7.5 14.4 42.7 0.1 33.7 6.2 2.3 0.0 6.6 11.6 66.0 5.1 12.9 0.0 0.9 15.6 11.1 0.0 0.0 7.2 0.0 6.7 87.7 40.8 9.4 10.0 16.7 9.1 6.3 12.8 10.9 0.0 4.2 4.9 0.0 5.4 2.4 0.0 3.2 4.1 3.2 1.7 1.3 3.1 6.8 3.5 8.5 6.6 0.0 3.1 5.0 1.6 16.4 16.2 14.0 20.1 15.2 22.8 21.1 19.2 21.2 16.8 18.2 18.5 104.4 0.0 7.7 212.9 34.6 11.2 3.0 2.0 0.6 42.7 1.4 2.8 106.3 1.5 3.6 1.8 45.9 0.3 22.0 0.0 0.0 2.1 110.1 7.2 287.8 110.6 0.0 12.2 276.1 2.7 0.5 66.1 2.0 6.5 1.3 17.0 49.6 13.4 1.2 10.1 261.9 0.0 0.0 3.8 25.6 141.8 30.7 6.3 26.6 479.7 10.7 7.2 7.2 968.6 7.3 2.5 0.0 102.0 33.2 3.7 0.0 1.6 1.5 43.4 78.9 99.2 74.2 17.4 15.7 1.1 8.7 0.7 36.2 12.0 0.0 3.8 ZFHX4 "FLJ20980, ZFH4" ENSG00000091656 "Zinc finger homeobox 4" Q86UP3 8 76681239-76867281 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3" "Cell type enhanced" "Detected in many" "Astrocytes: 358.5;Bipolar cells: 87.2;Oligodendrocyte precursor cells: 234.2;Oligodendrocytes: 222.6;Skeletal myocytes: 120.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 16.8;TIME: 33.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023837 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli fibrillar center" "HPA023837: AB_1859013" "unprognostic (2.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.63e-3)" "unprognostic (6.14e-8)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.61e-2)" "unprognostic (2.61e-2)" "unprognostic (3.79e-2)" "unprognostic (9.15e-4)" "unprognostic (3.18e-2)" "unprognostic (1.17e-3)" "unprognostic (6.20e-7)" "unprognostic (3.50e-3)" "unprognostic (2.51e-1)" "unprognostic (4.50e-4)" "unprognostic (5.89e-4)" 3.0 3.6 7.5 0.5 12.0 0.0 2.1 0.9 9.3 3.2 0.0 3.2 0.0 0.8 3.2 0.3 0.6 0.9 0.4 6.0 18.9 0.3 2.8 0.1 0.3 11.3 23.3 1.9 0.2 0.2 2.8 0.1 17.7 1.0 0.5 2.2 0.6 5.5 2.8 0.4 0.3 1.1 7.0 0.1 0.8 6.7 15.3 0.6 0.3 3.1 0.0 2.7 2.6 15.0 0.0 2.2 3.8 0.0 7.2 8.7 0.0 3.3 4.6 3.8 3.9 0.0 0.0 0.0 5.8 5.7 1.7 0.4 7.8 1.0 7.6 0.0 10.3 0.1 0.0 0.0 1.9 0.0 0.5 16.8 0.4 9.5 3.0 6.5 0.7 0.0 0.1 0.3 7.0 0.0 0.0 0.0 0.6 0.4 7.1 0.0 6.8 0.0 5.8 0.0 0.0 6.5 0.0 0.8 0.0 0.0 0.9 0.0 33.4 3.7 5.6 10.6 7.4 10.9 1.2 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 12.0 0.9 9.3 6.0 18.9 11.3 23.3 17.7 7.0 15.3 15.0 5.4 0.0 1.5 358.5 0.3 0.5 0.1 1.0 2.2 87.2 2.4 2.2 4.0 42.9 0.3 5.5 2.1 0.1 0.2 0.0 0.0 0.1 70.0 0.0 1.1 2.0 0.0 0.0 13.7 0.0 0.0 37.5 0.0 0.0 0.0 0.1 1.1 30.5 0.4 5.0 12.6 0.2 0.0 0.6 1.8 24.3 13.7 0.7 0.0 29.0 0.0 15.0 0.0 234.2 222.6 0.0 0.0 21.4 0.1 0.3 0.0 0.3 0.3 5.8 0.0 120.6 8.1 12.4 2.3 1.2 1.1 0.0 0.6 10.0 0.0 0.9 ZMYND19 MIZIP ENSG00000165724 "Zinc finger MYND-type containing 19" Q96E35 9 137582081-137590512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 287.8" "Group enriched" "Detected in many" 14 "Cone photoreceptor cells: 244.0;Rod photoreceptor cells: 680.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020642, HPA050761" Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA020642: AB_1859078, HPA050761: AB_2681228" "unprognostic (2.30e-2)" "unprognostic (9.62e-3)" "unprognostic (3.45e-2)" "unprognostic (7.99e-2)" "unprognostic (2.66e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.18e-1)" "unprognostic (2.48e-1)" "unprognostic (1.35e-1)" "unprognostic (9.33e-2)" "unprognostic (1.99e-2)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (4.30e-2)" "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" 11.9 16.5 19.6 9.4 19.9 9.1 11.9 18.8 23.9 14.2 18.6 12.4 8.8 11.2 5.0 26.5 11.4 7.2 14.1 20.0 19.5 12.9 21.1 12.0 11.9 18.7 19.2 12.9 16.1 8.0 16.9 8.5 19.7 16.5 5.7 287.8 15.9 7.1 14.2 27.7 12.4 6.8 18.9 15.1 22.2 49.5 19.4 9.5 10.8 8.8 9.4 13.3 16.6 19.8 28.9 44.7 41.8 45.5 22.1 21.3 42.1 38.8 25.8 41.7 31.8 53.1 28.7 51.7 43.6 25.8 40.2 71.7 51.3 38.9 13.2 33.8 49.7 26.9 86.1 41.8 34.4 58.4 33.9 16.8 58.7 38.0 37.1 18.4 22.3 40.5 66.3 22.2 25.6 97.2 68.4 88.7 60.7 86.4 61.9 73.8 36.8 79.6 25.7 24.2 60.1 39.4 37.4 79.4 35.4 18.5 53.7 89.9 21.3 51.1 38.9 76.8 63.8 21.4 54.9 56.8 31.6 44.8 35.9 0.0 0.3 0.3 0.5 1.6 1.2 0.8 0.3 0.2 0.3 0.3 0.5 0.4 0.0 0.1 0.2 0.9 1.0 0.1 19.6 19.9 18.8 23.9 20.0 19.5 18.7 19.2 19.7 18.9 19.4 19.8 6.1 9.6 7.2 3.6 4.0 17.5 5.6 3.2 5.2 23.6 14.9 19.2 6.2 2.8 2.4 1.8 244.0 5.2 6.8 5.3 0.0 3.2 4.5 6.5 12.8 5.6 2.4 6.9 4.1 3.6 6.8 6.3 10.7 8.1 1.3 10.6 3.9 7.6 4.4 11.8 4.0 8.8 6.1 3.2 5.7 4.4 2.8 3.6 5.4 1.9 2.2 31.6 5.2 2.0 2.1 4.2 4.6 3.0 10.9 10.2 1.9 3.1 1.3 680.0 0.0 6.9 6.7 27.8 28.7 4.5 22.9 4.5 4.6 8.5 7.8 7.1 ZMYND8 "PRKCBP1, RACK7" ENSG00000101040 "Zinc finger MYND-type containing 8" Q9ULU4 20 47209214-47356889 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020949 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Golgi apparatus" "HPA020949: AB_1857223" "prognostic unfavorable (2.56e-4)" "unprognostic (5.09e-2)" "unprognostic (5.84e-2)" "unprognostic (3.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.62e-4)" "unprognostic (2.10e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (8.64e-2)" "unprognostic (3.62e-1)" "prognostic unfavorable (7.06e-5)" "unprognostic (3.59e-2)" "unprognostic (7.50e-2)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" 13.1 32.7 25.4 10.5 21.3 26.0 14.7 26.2 36.2 11.9 47.8 14.1 11.0 9.8 33.3 16.0 15.9 12.3 12.5 35.5 29.5 18.5 10.9 11.1 12.8 30.5 22.9 13.6 12.3 11.6 25.9 11.8 33.0 11.8 14.5 20.1 14.6 14.6 15.3 19.9 16.2 8.7 9.4 18.3 20.0 14.2 25.2 14.6 11.0 11.0 12.8 14.5 14.9 37.3 27.6 17.2 90.5 36.6 15.2 21.3 59.4 21.7 17.8 22.3 22.8 107.7 26.0 26.5 34.4 16.3 27.1 18.7 39.4 96.0 33.3 11.4 14.9 110.4 6.3 95.9 55.4 11.9 55.9 20.9 43.4 24.8 94.1 40.4 61.0 9.5 90.6 17.7 41.0 32.1 4.4 45.4 85.9 20.3 24.3 55.8 15.0 22.9 30.4 49.6 38.0 14.3 10.3 32.4 44.4 70.3 17.0 22.6 143.6 23.9 16.6 23.3 20.2 12.5 25.2 23.2 80.8 18.3 80.3 34.8 7.4 10.4 8.7 7.5 8.7 15.3 8.8 9.0 4.7 18.3 11.4 11.8 19.8 16.3 6.8 16.5 9.3 4.3 25.4 21.3 26.2 36.2 35.5 29.5 30.5 22.9 33.0 9.4 25.2 37.3 48.2 44.8 78.5 94.0 36.6 8.8 32.2 44.6 15.9 108.1 29.3 20.7 23.7 28.6 74.3 90.1 160.6 23.1 36.2 64.0 15.6 36.5 13.6 111.3 29.8 31.7 56.3 112.9 153.8 28.7 42.0 24.2 41.8 124.4 32.2 44.8 30.7 16.1 21.9 85.8 113.5 49.2 42.7 48.8 12.8 21.9 27.7 31.8 10.6 49.6 25.0 24.4 40.2 89.0 138.7 47.1 42.3 26.7 29.7 23.9 56.8 12.0 82.3 50.0 32.9 33.4 27.5 6.3 29.9 19.2 8.4 66.5 34.2 39.3 32.1 24.2 ZNF106 "SH3BP3, ZFP106, ZNF474" ENSG00000103994 "Zinc finger protein 106" Q9H2Y7 15 42412823-42491141 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 392.5;tongue: 465.5" "Cell type enriched" "Detected in all" 9 "Cardiomyocytes: 1836.4" "Cancer enhanced" "Detected in all" "melanoma: 29.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 161.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054267 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoli "Nucleoplasm, Cytosol" "HPA054267: AB_2682431" "unprognostic (2.15e-2)" "unprognostic (3.31e-1)" "unprognostic (7.10e-2)" "unprognostic (2.61e-2)" "unprognostic (4.01e-2)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" "unprognostic (2.49e-1)" "unprognostic (3.96e-1)" "unprognostic (1.33e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.76e-3)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-1)" "unprognostic (4.09e-3)" 32.4 11.2 20.8 14.3 29.8 24.4 17.9 19.0 28.1 18.0 109.2 19.7 10.0 15.9 17.3 18.5 12.7 17.2 175.6 23.3 22.6 16.5 8.7 20.9 17.5 23.6 29.1 15.9 10.3 17.8 10.3 12.9 22.5 20.9 13.9 22.0 12.9 14.7 392.5 11.7 13.3 23.0 20.8 17.1 12.8 14.3 27.4 15.6 13.2 465.5 18.6 14.6 9.1 27.7 27.2 15.1 29.0 33.5 86.8 68.5 16.1 21.7 22.2 19.6 20.5 33.9 7.8 17.8 19.0 27.7 22.8 31.8 28.3 23.4 29.5 29.0 13.1 34.7 37.9 13.6 23.2 43.1 20.2 55.4 17.8 28.0 32.6 19.5 32.3 23.2 43.0 2.7 36.9 11.9 16.2 13.3 11.0 26.1 15.1 15.2 54.3 10.8 12.1 31.5 16.5 10.2 45.0 22.8 28.7 23.4 20.0 30.0 42.2 20.8 32.5 26.1 32.3 14.8 32.2 76.5 18.4 33.6 37.6 86.8 63.8 27.1 15.6 52.3 13.5 21.8 13.0 13.3 35.6 26.8 11.3 10.6 161.0 12.5 66.8 36.0 13.0 18.0 20.8 29.8 19.0 28.1 23.3 22.6 23.6 29.1 22.5 20.8 27.4 27.7 58.0 134.6 107.7 46.0 49.6 38.5 57.9 41.9 44.3 58.5 50.9 46.0 1836.4 62.9 57.0 29.5 95.9 37.9 67.2 31.7 41.1 43.2 197.2 75.2 67.1 69.9 40.2 50.5 73.3 42.4 39.3 141.7 31.1 37.5 44.9 49.5 62.8 40.1 53.5 35.3 62.9 32.6 32.6 132.7 43.4 105.2 37.6 89.8 65.8 47.8 124.3 53.6 66.9 31.2 34.2 65.7 26.9 92.6 50.7 74.8 39.7 41.5 161.1 79.9 46.0 151.2 70.0 62.3 38.1 49.8 29.8 30.6 46.0 85.9 36.6 68.2 ZNF107 "smap-7, ZFD25, ZNF588" ENSG00000196247 "Zinc finger protein 107" Q9UII5 7 64666083-64711582 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.2" "Cell type enhanced" "Detected in many" "B-cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 47.0;REH: 49.5;U-698: 51.2" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.25e-1)" "unprognostic (1.70e-1)" "unprognostic (3.50e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-1)" "unprognostic (9.11e-2)" "unprognostic (1.67e-2)" "unprognostic (2.51e-2)" "unprognostic (4.13e-3)" "unprognostic (1.62e-2)" "unprognostic (2.34e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (3.32e-1)" "unprognostic (1.66e-1)" "unprognostic (5.49e-2)" "unprognostic (7.15e-3)" 2.3 5.9 1.5 8.8 2.5 8.6 8.3 2.9 1.9 6.8 0.7 2.7 2.7 2.9 2.3 2.7 2.7 2.5 1.3 1.8 2.0 2.1 1.6 2.3 16.2 2.8 2.1 4.4 1.6 2.1 1.8 3.1 2.7 3.3 3.5 3.3 4.8 2.6 0.8 7.5 7.7 2.1 2.1 8.5 3.7 2.8 2.1 13.4 5.0 1.8 14.2 3.2 3.6 3.7 6.8 4.1 11.3 19.8 2.6 2.7 8.3 5.0 3.3 7.4 9.8 6.3 6.3 39.6 8.9 3.3 10.0 5.2 12.6 5.1 11.1 9.7 8.5 7.8 6.6 3.5 1.1 14.9 13.3 4.6 3.5 6.4 3.7 3.7 3.7 36.1 13.8 20.2 6.6 5.7 47.0 15.9 22.0 4.2 4.5 49.5 9.1 8.8 3.7 13.3 12.6 10.1 7.8 8.0 5.1 15.6 12.6 9.7 3.2 12.3 5.0 4.7 7.4 9.4 9.1 51.2 2.8 10.0 8.1 12.0 0.7 1.5 3.4 1.7 3.6 9.0 4.6 4.8 1.1 10.1 6.0 5.8 13.7 2.6 1.3 2.8 4.3 1.8 1.5 2.5 2.9 1.9 1.8 2.0 2.8 2.1 2.7 2.1 2.1 3.7 7.9 12.8 4.2 10.4 45.2 2.2 3.2 3.2 8.6 6.2 13.9 5.8 3.8 5.7 5.4 7.3 2.1 2.7 9.0 1.3 1.9 2.6 8.2 5.1 5.7 6.9 6.6 5.9 6.2 3.1 2.4 6.7 5.1 5.9 0.0 15.0 4.2 0.6 1.9 3.3 9.7 2.9 2.0 3.8 1.5 7.8 4.4 4.8 0.0 10.3 1.7 4.1 10.3 22.6 22.1 3.9 2.4 3.4 22.8 3.5 2.0 1.9 3.3 5.7 6.6 4.0 3.9 4.3 4.7 5.5 4.1 2.5 17.9 17.5 3.6 3.8 ZNF19 "KOX12, MGC51021" ENSG00000157429 "Zinc finger protein 19" P17023 16 71464555-71565089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.9;Spermatocytes: 15.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA063685 Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA063685: AB_2685090" "unprognostic (5.59e-4)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-4)" "unprognostic (6.02e-3)" "unprognostic (4.92e-2)" "unprognostic (3.34e-2)" "unprognostic (6.97e-3)" "unprognostic (2.23e-1)" "unprognostic (4.84e-2)" "unprognostic (8.90e-4)" "unprognostic (1.31e-1)" "unprognostic (3.04e-6)" "unprognostic (3.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.83e-2)" "unprognostic (4.87e-2)" 3.3 3.2 1.7 2.4 3.1 2.6 3.5 2.5 6.0 2.0 3.1 2.4 3.7 3.9 8.3 4.4 8.3 6.5 4.3 4.3 0.6 3.5 2.3 4.3 3.1 0.4 0.1 4.2 6.2 4.3 5.3 1.8 0.0 3.2 2.1 11.3 3.4 2.0 9.7 6.5 3.1 1.5 0.0 2.7 2.9 16.2 1.6 1.1 8.2 1.7 1.4 1.7 0.6 5.7 1.2 1.0 2.9 2.8 1.3 0.9 2.0 1.9 0.9 1.1 1.2 2.1 3.9 1.7 2.1 0.9 2.0 1.4 1.4 1.7 0.4 1.3 1.3 2.3 2.2 3.2 0.8 2.3 1.9 2.1 1.8 1.5 3.2 2.5 0.5 3.0 1.3 2.1 1.4 1.8 1.6 1.5 1.5 0.7 2.5 1.0 2.5 0.6 1.6 2.2 4.0 3.0 3.3 1.1 2.6 1.9 2.2 1.8 1.0 3.3 1.7 2.1 1.8 1.9 1.9 0.4 2.7 1.3 1.8 2.3 0.9 0.8 1.1 0.8 0.3 2.1 1.2 1.1 0.7 2.4 1.5 1.4 1.7 0.9 1.0 1.3 0.5 0.6 1.7 3.1 2.5 6.0 4.3 0.6 0.4 0.1 0.0 0.0 1.6 5.7 1.4 0.0 3.2 3.9 3.7 0.3 2.0 2.1 1.2 3.8 3.1 1.8 1.2 1.5 2.3 1.8 10.4 1.4 2.3 1.8 5.9 4.4 7.3 6.3 1.3 1.6 1.2 3.6 1.7 1.4 0.8 2.1 0.5 1.2 0.0 5.0 2.2 4.1 1.4 10.1 1.6 2.0 2.0 1.0 1.6 4.4 0.6 0.9 0.0 2.8 1.3 3.5 0.0 2.0 2.1 2.2 1.7 1.9 0.8 1.3 3.6 3.3 10.0 25.9 6.6 2.2 2.0 15.3 7.6 0.8 0.6 0.5 1.8 3.4 1.5 1.0 ZNF215 "ZKSCAN11, ZSCAN43" ENSG00000149054 "Zinc finger protein 215" Q9UL58 11 6926404-7001004 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 13.7;Inhibitory neurons: 8.5;Plasma cells: 27.5;Spermatogonia: 9.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-698: 19.8" "Low region specificity" "Detected in many" "HPA047243, HPA051010" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA047243: , HPA051010: AB_2681308" "unprognostic (2.18e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-2)" "unprognostic (1.08e-1)" "unprognostic (8.18e-2)" "unprognostic (4.76e-2)" "unprognostic (1.01e-4)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (1.05e-1)" "unprognostic (3.44e-1)" "unprognostic (1.45e-2)" "unprognostic (9.01e-3)" "unprognostic (4.29e-3)" "unprognostic (7.89e-2)" "unprognostic (1.21e-1)" "unprognostic (1.90e-1)" 0.4 0.4 0.4 1.3 0.4 0.7 1.3 0.2 0.5 0.8 0.1 2.0 2.2 0.7 0.6 0.9 0.4 0.5 0.4 0.4 0.5 1.0 0.3 0.5 3.4 0.5 0.4 0.8 2.2 0.0 0.2 0.2 0.4 0.8 2.6 0.4 1.4 0.4 0.2 0.5 1.9 0.5 0.2 1.6 0.8 1.5 0.6 1.2 0.8 0.1 4.2 1.1 0.7 0.3 2.9 1.1 1.8 0.2 1.2 1.7 6.4 7.0 5.7 3.6 6.5 0.2 0.0 10.1 2.1 3.2 4.3 3.1 4.8 6.4 6.3 0.0 7.5 0.0 0.3 0.0 1.2 6.5 0.0 3.2 3.1 0.1 7.0 1.4 5.3 0.1 11.5 3.1 1.3 0.0 0.1 0.0 8.9 0.0 1.6 0.0 0.0 1.3 0.1 5.3 0.0 0.2 0.0 2.4 0.0 4.4 0.1 2.4 2.8 2.0 5.8 2.4 0.0 0.3 0.1 19.8 4.8 0.0 1.9 1.5 0.4 0.1 0.1 0.2 0.0 0.6 0.1 0.3 0.4 0.5 0.3 0.1 0.6 0.2 0.1 0.7 0.2 0.3 0.4 0.4 0.2 0.5 0.4 0.5 0.5 0.4 0.4 0.2 0.6 0.3 0.2 0.0 0.0 0.3 2.5 0.4 1.7 1.0 1.8 0.6 0.7 0.3 0.2 0.0 0.9 7.3 6.2 0.4 0.1 0.9 1.9 0.1 0.3 0.8 1.8 0.6 1.2 2.5 13.7 1.8 2.6 1.1 0.0 0.9 1.3 0.6 0.0 0.9 0.4 3.3 8.5 3.5 0.0 0.3 0.0 0.3 0.0 0.8 1.8 3.7 0.0 0.1 0.0 1.5 0.4 0.3 0.8 0.0 27.5 0.6 2.0 1.1 0.4 0.0 0.0 0.2 0.7 5.6 9.1 2.3 0.3 0.0 0.8 2.2 2.2 0.8 ZNF23 "KOX16, Zfp612, ZNF359, ZNF612" ENSG00000167377 "Zinc finger protein 23" P17027 16 71447597-71463095 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.0;Excitatory neurons: 10.0;Inhibitory neurons: 11.2;Oligodendrocyte precursor cells: 13.0;Oligodendrocytes: 16.0;Respiratory ciliated cells: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023534 Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA023534: AB_1859140" "unprognostic (8.49e-2)" "unprognostic (1.46e-2)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (3.98e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (9.89e-3)" "unprognostic (2.12e-1)" "unprognostic (8.37e-3)" "unprognostic (2.19e-2)" "unprognostic (2.62e-3)" "unprognostic (3.65e-1)" "unprognostic (6.94e-2)" "unprognostic (9.59e-2)" "unprognostic (6.04e-2)" 5.5 4.3 8.6 5.3 8.4 4.4 6.2 8.8 9.9 5.8 8.9 5.6 2.8 6.9 8.0 4.2 7.1 3.6 5.1 8.6 8.5 5.6 5.4 5.4 6.2 8.4 8.3 8.2 4.6 5.4 14.3 4.7 8.1 5.3 5.7 16.9 4.3 5.8 6.5 5.8 5.0 6.9 8.2 5.7 4.1 6.9 8.6 4.9 7.5 7.1 6.0 4.2 3.5 9.8 7.8 4.7 12.0 8.8 7.6 6.6 7.8 17.1 15.9 11.7 8.6 6.1 7.6 15.1 4.2 13.1 11.4 4.7 7.9 10.2 13.7 4.0 5.2 6.7 5.0 6.5 9.2 12.3 5.7 10.7 9.0 12.1 18.6 10.9 4.1 7.9 11.1 2.9 12.5 13.0 6.4 6.0 13.4 4.0 3.9 3.3 5.3 4.6 7.7 6.4 9.9 12.8 5.5 3.9 5.3 7.5 5.1 6.4 11.5 21.2 7.2 5.9 10.7 6.5 10.6 19.8 16.0 6.2 13.2 0.8 0.8 0.5 1.9 1.8 1.8 1.3 1.0 2.1 1.1 2.7 2.1 1.5 0.0 2.6 1.0 1.9 1.9 0.9 8.6 8.4 8.8 9.9 8.6 8.5 8.4 8.3 8.1 8.2 8.6 9.8 0.6 6.4 2.3 15.0 2.6 0.3 0.3 0.2 2.8 2.6 0.7 0.6 0.4 0.0 3.2 0.0 6.2 0.2 0.4 0.5 1.9 2.0 0.2 1.0 1.0 1.1 0.0 7.8 10.0 1.0 0.3 0.9 1.5 0.5 2.5 1.3 1.1 0.5 0.4 3.3 11.2 1.0 0.0 0.3 0.3 0.0 0.6 0.5 0.0 6.5 0.4 1.4 2.1 13.0 16.0 1.5 1.4 0.0 1.5 0.3 0.7 0.3 9.2 3.3 0.0 0.7 0.9 1.5 1.4 2.3 0.0 0.0 1.4 0.5 1.5 0.1 ZNF385B "FLJ25270, ZNF533" ENSG00000144331 "Zinc finger protein 385B" Q569K4 2 179441982-179861612 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 88.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 124.2;Bipolar cells: 220.1;Excitatory neurons: 566.5;Inhibitory neurons: 393.1;Rod photoreceptor cells: 133.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 17.6;HAP1: 31.9;U-698: 91.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046086 Approved "Nucleoli fibrillar center" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "HPA046086: AB_2679532" "prognostic favorable (4.86e-8)" "unprognostic (8.05e-3)" "unprognostic (1.14e-1)" "unprognostic (3.91e-2)" "unprognostic (3.49e-1)" "unprognostic (1.51e-2)" "unprognostic (3.49e-3)" "unprognostic (1.14e-1)" "unprognostic (8.99e-3)" "unprognostic (3.56e-2)" "unprognostic (4.59e-2)" "unprognostic (2.69e-1)" "prognostic favorable (1.04e-9)" "unprognostic (7.76e-2)" "unprognostic (2.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-3)" 2.3 5.2 4.1 0.3 25.4 0.4 6.9 27.3 17.4 1.6 0.0 2.4 0.3 1.5 3.8 1.1 1.1 0.7 24.1 6.9 1.9 8.5 19.1 18.4 1.6 9.6 3.0 15.2 0.3 0.0 1.0 2.2 10.8 12.6 0.7 88.7 1.2 0.5 17.1 1.6 0.8 0.4 0.0 0.5 14.2 10.3 6.8 0.5 1.2 10.9 0.6 1.5 2.2 9.5 0.0 0.0 7.3 0.3 0.1 0.3 0.1 0.0 0.0 0.4 0.8 0.0 0.0 17.6 0.1 0.0 5.9 0.0 31.9 0.0 0.4 0.0 4.3 0.2 0.7 1.2 0.0 0.0 0.0 3.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.3 0.1 0.1 1.3 0.0 2.0 0.0 1.3 1.3 1.8 0.0 0.7 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.3 2.3 0.3 1.5 0.0 0.0 91.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 25.4 27.3 17.4 6.9 1.9 9.6 3.0 10.8 0.0 6.8 9.5 1.0 28.9 124.2 12.1 0.0 3.4 0.7 0.0 0.0 220.1 5.1 2.2 32.4 5.7 1.3 0.0 54.2 0.0 0.0 0.3 82.2 0.0 58.4 1.0 0.1 0.5 1.8 0.0 566.5 0.0 0.0 6.4 3.1 1.7 1.3 19.6 1.4 14.3 0.3 1.7 393.1 0.0 0.0 0.0 0.3 29.2 0.6 0.5 1.8 89.0 0.0 6.4 0.0 20.1 10.7 0.1 0.0 0.4 0.1 4.9 0.0 24.5 1.5 133.7 0.0 5.2 1.6 6.2 1.8 0.1 0.9 0.1 0.3 3.3 0.1 0.9 ZNF385D "FLJ22419, ZNF659" ENSG00000151789 "Zinc finger protein 385D" Q9H6B1 3 21412218-22373321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 44.0;testis: 15.1" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 1766.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 8 "cerebellum: 44.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.8;hTERT-RPE1: 5.4;LHCN-M2: 5.3;PC-3: 5.3;RPTEC TERT1: 15.1;U-87 MG: 21.1" "Low region specificity" "Detected in all" HPA036190 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA036190: AB_10602355" "unprognostic (4.07e-2)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (3.23e-2)" "unprognostic (1.64e-1)" "unprognostic (1.74e-1)" "unprognostic (8.20e-2)" "unprognostic (6.60e-2)" "unprognostic (7.84e-2)" "unprognostic (3.73e-1)" "unprognostic (2.35e-1)" "unprognostic (9.01e-2)" "unprognostic (3.49e-7)" "unprognostic (8.70e-3)" "unprognostic (5.38e-2)" "unprognostic (7.76e-3)" "unprognostic (2.15e-5)" 3.8 0.2 2.6 1.4 4.5 0.3 2.2 44.0 5.4 1.8 0.0 0.8 0.3 1.1 0.5 2.0 0.7 2.7 1.8 1.7 2.5 1.4 0.1 0.6 0.8 3.3 4.5 0.6 0.6 0.2 0.1 0.0 3.6 1.3 0.5 7.3 0.7 1.1 1.0 0.7 0.5 1.7 1.5 0.3 0.4 15.1 3.1 0.7 0.5 3.3 1.0 2.7 1.2 5.3 0.0 0.0 0.3 0.0 2.0 4.3 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.2 0.0 5.4 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 15.1 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.1 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 2.6 4.5 44.0 5.4 1.7 2.5 3.3 4.5 3.6 1.5 3.1 5.3 82.2 12.8 13.4 17.3 1.4 9.7 0.7 6.2 1.8 58.8 1.5 6.3 3.6 1.5 19.2 1.8 8.4 0.3 1.4 0.9 27.4 0.6 174.9 0.2 1.9 89.0 0.0 12.6 267.5 0.7 0.2 20.5 0.0 0.3 5.1 1.8 2.2 5.8 0.4 323.0 1766.6 0.7 0.0 0.0 14.0 274.5 16.8 4.9 12.4 64.6 0.6 114.3 1.0 159.3 12.7 1.4 0.6 13.5 0.3 1.7 2.3 6.6 4.4 31.0 13.1 22.0 20.2 50.4 2.0 0.6 7.7 0.1 1.5 34.3 0.7 1.0 ZNF503 "FLJ45745, MGC2555, Nlz2" ENSG00000165655 "Zinc finger protein 503" Q96F45 10 75397830-75401764 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 255.0;Squamous epithelial cells: 189.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 115.1;PC-3: 149.2;U-87 MG: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026848 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Nucleoplasm "HPA026848: AB_10610704" "unprognostic (1.18e-1)" "unprognostic (8.56e-2)" "unprognostic (8.63e-3)" "unprognostic (7.41e-2)" "unprognostic (2.82e-1)" "unprognostic (3.57e-2)" "unprognostic (9.63e-2)" "unprognostic (7.42e-2)" "unprognostic (3.42e-2)" "unprognostic (3.22e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.97e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" 14.5 39.9 6.1 3.1 10.1 2.0 9.2 3.8 5.2 34.5 1.0 17.7 8.1 44.1 10.3 20.1 23.8 2.4 9.0 7.4 5.5 25.6 7.1 14.2 1.5 12.0 9.2 46.3 25.4 4.6 4.8 3.3 7.6 17.5 1.8 1.4 9.5 17.6 3.6 5.3 8.5 7.7 10.0 8.0 16.3 2.4 8.1 1.1 7.8 2.1 1.0 13.8 18.2 6.5 5.2 4.9 1.1 6.3 10.6 7.1 1.6 4.6 2.8 1.9 1.7 7.5 20.4 0.0 13.4 4.6 1.1 9.4 0.7 4.9 1.4 0.0 115.1 0.0 12.4 24.8 8.5 6.1 12.9 19.1 4.8 3.5 2.0 16.6 0.5 0.5 0.1 0.2 2.6 2.7 0.2 18.8 0.1 3.8 149.2 0.0 5.6 0.1 2.8 4.1 4.1 5.2 8.5 0.6 27.1 1.0 1.0 4.2 3.9 14.6 16.3 30.7 13.0 0.0 0.0 0.0 44.9 27.2 11.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 10.1 3.8 5.2 7.4 5.5 12.0 9.2 7.6 10.0 8.1 6.5 27.2 38.5 11.6 2.3 1.7 27.1 35.6 15.0 255.0 23.7 7.7 42.3 20.4 10.0 10.1 40.5 20.9 0.5 2.1 0.8 58.7 45.9 0.1 53.2 72.2 41.0 3.6 5.3 12.6 34.7 0.3 60.1 18.3 48.1 6.3 2.7 44.6 10.3 13.5 6.7 3.2 6.7 10.2 27.4 30.5 2.0 59.7 30.7 24.9 13.1 8.2 7.7 0.0 4.0 0.7 33.2 1.5 49.2 3.9 19.7 13.4 32.5 1.7 26.3 39.5 10.2 78.1 0.2 6.0 189.3 13.9 0.3 4.0 24.5 9.7 14.3 ZNF552 FLJ21603 ENSG00000178935 "Zinc finger protein 552" Q9H707 19 57803841-57814913 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 23.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 25.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 25.3" "Cell line enhanced" "Detected in all" "BEWO: 30.3;RT4: 42.5;T-47d: 69.6" "Low region specificity" "Detected in all" "HPA043800, HPA053762, HPA072145" Uncertain Uncertain Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA043800: AB_2678675, HPA053762: AB_2682252, HPA072145: " "prognostic favorable (4.57e-4)" "unprognostic (2.09e-1)" "prognostic favorable (2.66e-4)" "unprognostic (9.03e-2)" "unprognostic (9.89e-2)" "prognostic favorable (9.96e-4)" "unprognostic (3.03e-2)" "unprognostic (1.29e-3)" "unprognostic (3.36e-3)" "unprognostic (6.72e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-1)" "unprognostic (2.24e-3)" "unprognostic (2.41e-2)" "unprognostic (9.01e-2)" "unprognostic (3.09e-1)" "unprognostic (2.04e-3)" 3.0 2.3 3.0 4.7 3.1 8.1 26.0 14.9 6.5 9.8 9.3 9.4 7.1 5.0 5.4 5.5 5.6 8.7 2.9 3.4 3.0 7.1 4.7 6.0 5.3 2.8 2.0 4.2 4.2 6.0 2.5 6.5 2.3 12.4 12.1 4.0 17.5 6.9 4.9 9.7 7.3 3.0 0.5 6.0 13.9 3.0 3.5 5.0 4.1 2.7 5.5 14.7 5.8 3.4 5.6 3.2 3.7 5.9 3.0 1.5 30.3 2.0 2.4 4.5 2.5 9.6 8.8 7.6 3.8 3.6 1.0 4.8 7.6 5.0 5.4 3.4 15.1 2.6 8.4 7.1 7.1 8.5 3.4 3.3 10.9 3.1 3.2 2.8 6.0 8.0 5.5 2.5 3.0 5.0 3.7 2.5 5.2 6.9 7.3 7.6 4.7 8.0 13.4 42.5 4.9 3.5 10.2 22.6 5.1 10.4 69.6 3.5 4.5 3.8 4.2 2.5 3.5 11.0 8.1 6.1 3.1 6.4 2.2 2.1 3.3 7.4 2.7 3.3 2.5 3.7 3.4 4.3 1.7 3.7 4.5 3.8 25.3 2.4 1.4 2.3 3.0 2.4 3.0 3.1 14.9 6.5 3.4 3.0 2.8 2.0 2.3 0.5 3.5 3.4 2.9 12.8 3.1 4.2 7.8 2.5 14.8 9.7 8.0 6.2 19.4 9.8 3.1 18.6 15.0 20.2 2.1 22.1 5.3 9.4 25.4 6.9 5.7 20.2 4.9 3.7 8.4 6.1 7.7 1.8 5.2 3.8 19.4 15.0 8.8 14.2 7.1 4.2 5.2 3.3 8.1 14.5 14.2 2.4 3.1 1.5 2.8 3.6 1.8 1.9 3.1 2.3 2.1 4.5 5.1 3.1 13.4 2.2 4.8 8.3 15.6 4.8 20.5 12.7 6.6 2.9 3.5 3.8 4.6 7.0 2.7 21.3 7.1 5.4 9.3 14.2 ZNF652 KIAA0924 ENSG00000198740 "Zinc finger protein 652" Q9Y2D9 17 49289206-49362473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 18.0" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044408 Uncertain Approved Nucleoplasm No No "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA044408: AB_2678932" "unprognostic (1.33e-2)" "unprognostic (5.54e-2)" "unprognostic (1.15e-1)" "prognostic favorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (7.31e-3)" "unprognostic (2.34e-1)" "unprognostic (4.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-1)" "unprognostic (4.09e-3)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.30e-2)" 2.1 2.3 4.6 2.8 11.4 3.7 9.6 6.7 4.7 3.2 1.5 2.8 2.6 2.1 2.0 2.0 2.1 2.2 1.6 3.6 6.2 2.5 4.0 2.8 2.9 10.7 8.2 2.8 2.4 3.6 1.0 2.6 11.4 3.3 2.9 4.5 4.4 2.4 10.5 6.6 2.1 2.7 5.2 4.6 3.4 3.7 7.9 3.4 3.6 2.5 3.0 2.1 1.1 18.0 4.3 2.9 3.2 4.1 4.3 2.3 4.3 1.6 2.6 1.8 2.1 6.8 2.7 9.7 5.0 3.3 1.4 3.0 2.9 3.1 2.9 3.3 2.6 3.5 5.0 4.7 1.6 2.9 5.3 3.2 2.8 1.6 2.9 1.8 2.2 4.8 2.7 8.1 1.8 6.0 4.3 1.6 3.2 2.5 2.1 3.4 6.6 4.6 2.4 5.7 5.9 4.0 2.8 3.9 4.2 4.8 7.1 4.1 3.6 5.9 4.4 2.6 2.6 10.3 7.6 6.3 3.2 2.6 2.2 7.7 3.0 3.2 2.6 2.6 3.5 1.9 1.9 2.0 2.1 2.6 1.8 1.9 5.9 2.1 3.4 1.9 0.9 2.5 4.6 11.4 6.7 4.7 3.6 6.2 10.7 8.2 11.4 5.2 7.9 18.0 28.8 19.2 19.8 37.5 38.6 16.4 14.2 7.8 18.8 56.5 63.7 50.2 16.6 21.5 15.2 29.5 64.6 24.0 60.6 22.7 13.7 18.6 19.2 56.6 45.1 24.3 12.1 22.3 49.2 19.6 18.2 24.4 16.8 59.1 5.1 24.0 29.6 41.6 12.8 43.7 70.9 20.4 14.2 41.6 32.4 17.3 48.4 25.1 26.6 65.6 37.0 30.1 45.3 76.9 152.6 18.4 18.5 44.4 21.9 24.6 17.9 12.4 21.3 47.1 0.0 30.0 22.8 60.4 29.9 15.6 24.3 13.4 33.7 27.7 24.0 12.6 ZNF683 "Hobit, MGC33414" ENSG00000176083 "Zinc finger protein 683" Q8IZ20 1 26361634-26374522 "Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 81.9" "Group enriched" "Detected in some" 12 "Early spermatids: 473.7;Late spermatids: 482.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 172.4;memory CD8 T-cell: 113.1" "Lineage enriched" "Detected in many" 15 "T-cells: 172.4" "Group enriched" "Detected in some" 8 "NB-4: 2.2;OE19: 4.8" "Not detected" "Not detected" HPA023865 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "HPA023865: AB_2671333" "unprognostic (3.95e-3)" "unprognostic (5.58e-3)" "unprognostic (5.83e-2)" "prognostic favorable (2.90e-5)" "unprognostic (9.17e-2)" "unprognostic (8.98e-4)" "unprognostic (7.90e-2)" "unprognostic (5.05e-3)" "unprognostic (5.81e-3)" "unprognostic (1.29e-1)" "unprognostic (3.52e-2)" "unprognostic (9.30e-2)" "unprognostic (3.54e-8)" "unprognostic (5.90e-3)" "unprognostic (1.63e-1)" "unprognostic (1.14e-2)" "prognostic favorable (3.45e-5)" 0.2 0.4 0.3 0.6 0.6 1.9 0.8 0.3 0.3 0.9 0.1 0.3 0.3 0.6 0.1 0.7 1.7 1.7 0.8 0.8 0.3 0.3 0.6 4.7 1.9 1.1 0.3 1.0 0.3 0.2 0.3 0.4 0.5 0.9 0.5 0.0 10.1 0.8 0.1 0.5 0.6 0.3 0.5 2.2 3.4 81.9 0.5 2.9 1.1 0.0 0.4 0.9 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.2 0.1 172.4 0.1 0.4 0.2 35.4 113.1 0.0 0.0 13.4 63.2 0.9 11.8 3.8 0.3 1.1 24.2 0.3 0.6 0.3 0.3 0.8 0.3 1.1 0.3 0.5 0.5 0.5 0.6 0.9 3.2 0.6 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.7 1.1 0.2 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 473.7 0.2 0.5 0.8 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.4 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 482.4 1.8 1.8 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.0 1.2 1.7 0.1 0.0 0.2 0.7 0.0 0.0 0.4 0.7 3.3 2.2 0.2 0.0 0.0 39.8 0.0 0.0 0.0 ZNF80 pT17 ENSG00000174255 "Zinc finger protein 80" P51504 3 114234631-114237578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 3.1" "Cell type enhanced" "Detected in some" "dendritic cells: 3.2;granulocytes: 1.3;NK-cells: 2.1;Plasma cells: 1.4;T-cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Not detected" "Not detected" HPA065484 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA065484: AB_2685496" "unprognostic (6.27e-3)" "unprognostic (3.00e-2)" "unprognostic (4.42e-2)" "unprognostic (1.26e-1)" "unprognostic (4.52e-2)" "unprognostic (9.68e-5)" "unprognostic (5.36e-1)" "unprognostic (6.52e-3)" "unprognostic (2.80e-2)" "unprognostic (1.27e-2)" "unprognostic (6.25e-2)" "unprognostic (1.49e-1)" "unprognostic (6.69e-12)" "unprognostic (1.85e-1)" "unprognostic (3.10e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-2)" 0.1 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.7 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.7 0.0 0.4 0.0 5.2 0.1 0.1 0.0 ZNF92 "HPF12, TF12" ENSG00000146757 "Zinc finger protein 92" Q03936 7 65373799-65401136 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003173 Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA003173: AB_1080744" "unprognostic (1.07e-1)" "unprognostic (1.36e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "unprognostic (8.53e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (5.48e-3)" "unprognostic (1.30e-2)" "unprognostic (3.86e-2)" "unprognostic (5.83e-2)" "unprognostic (1.40e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-3)" 2.7 4.5 2.9 5.5 3.5 16.5 10.4 5.8 4.9 5.1 1.4 4.1 4.0 3.5 4.5 5.5 3.3 4.0 2.9 2.8 3.4 3.5 3.2 3.2 10.9 3.6 3.5 5.5 3.6 4.9 2.0 3.7 3.8 3.6 4.5 3.0 2.7 3.3 2.7 3.1 4.5 2.4 4.2 6.7 5.1 5.2 3.5 10.2 6.0 4.2 9.6 3.8 2.4 4.9 7.6 5.0 21.7 21.6 5.4 6.6 10.4 6.1 4.6 6.6 9.6 9.3 10.9 29.3 11.6 3.4 10.0 7.3 17.2 4.2 10.7 11.1 11.4 13.1 2.7 9.3 2.0 16.2 12.1 5.6 3.6 6.1 4.7 8.9 8.3 15.4 17.3 11.7 9.7 2.2 23.7 17.6 29.3 7.9 6.9 21.3 12.8 9.9 7.3 15.1 18.5 14.0 9.4 14.6 7.0 20.7 10.3 21.5 6.1 7.7 6.9 4.6 8.8 7.4 6.9 41.8 5.1 12.6 6.9 4.7 1.3 3.5 2.1 1.8 4.4 8.5 3.2 3.2 1.9 7.1 3.8 4.1 1.1 7.7 2.5 1.9 5.0 1.7 2.9 3.5 5.8 4.9 2.8 3.4 3.6 3.5 3.8 4.2 3.5 4.9 13.9 9.6 1.1 3.9 44.9 5.6 7.2 3.1 8.6 8.2 15.9 11.6 5.2 5.7 6.2 5.5 0.0 6.5 35.4 4.6 11.7 7.9 1.3 5.8 11.2 9.3 7.2 13.5 7.7 4.7 5.4 9.6 6.6 11.9 11.4 17.0 9.3 2.2 4.5 5.0 11.1 8.2 6.1 6.3 3.8 2.2 7.2 11.7 5.4 3.7 10.8 11.8 14.4 12.1 12.3 6.4 7.4 6.4 17.6 6.7 2.4 5.0 2.1 5.0 0.0 11.1 10.2 25.1 24.8 5.1 3.8 4.9 23.2 16.4 6.2 7.1 ZP1 ENSG00000149506 "Zona pellucida glycoprotein 1" P60852 11 60867562-60875693 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Early spermatids: 32.3;Late spermatids: 87.6" "Cancer enhanced" "Detected in single" "prostate cancer: 0.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 32 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 32 "dendritic cells: 3.1" "Group enriched" "Detected in some" 40 "RPMI-8226: 12.4;SK-BR-3: 3.3" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (6.40e-3)" "unprognostic (2.18e-4)" "unprognostic (1.63e-1)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (7.02e-2)" "unprognostic (8.27e-2)" "unprognostic (9.95e-2)" "unprognostic (1.94e-2)" "unprognostic (8.15e-3)" "unprognostic (2.52e-1)" "unprognostic (9.25e-4)" "unprognostic (5.31e-13)" "unprognostic (4.13e-2)" "unprognostic (2.38e-1)" "unprognostic (6.27e-2)" "unprognostic (5.61e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 1.3 0.3 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.1 0.7 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 32.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 87.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.1 5.0 1.9 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.1 ZSCAN1 "FLJ33779, ZNF915" ENSG00000152467 "Zinc finger and SCAN domain containing 1" Q8NBB4 19 58034025-58054631 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.8;pituitary gland: 15.9;testis: 8.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 11.7;Early spermatids: 28.2;Endometrial ciliated cells: 21.8;Late spermatids: 19.6;Spermatocytes: 13.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.0;HMC-1: 2.1;NTERA-2: 2.1;T-47d: 3.1" HPA007938 Uncertain Approved Nucleoli NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA007938: AB_1080768" "unprognostic (1.60e-3)" "unprognostic (2.44e-1)" "unprognostic (2.21e-1)" "unprognostic (3.58e-1)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (1.97e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-1)" "prognostic favorable (7.36e-4)" "unprognostic (1.41e-2)" "unprognostic (3.81e-2)" "unprognostic (1.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.32e-1)" "unprognostic (2.47e-2)" "unprognostic (3.60e-1)" 0.1 0.9 3.7 0.0 2.7 0.1 0.9 4.1 4.6 1.2 1.4 0.3 0.0 0.6 6.1 0.1 2.1 0.2 0.5 3.6 7.8 2.6 0.1 0.5 0.0 4.0 5.3 0.6 1.0 2.6 15.9 0.2 3.1 2.4 0.0 2.3 0.4 0.8 0.0 0.2 0.1 0.1 2.1 0.2 0.1 8.7 5.1 0.6 5.9 0.0 0.0 0.5 0.3 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.6 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 2.7 4.1 4.6 3.6 7.8 4.0 5.3 3.1 2.1 5.1 1.6 0.1 0.0 0.0 3.6 0.0 0.0 0.4 0.2 0.0 3.4 1.8 2.2 1.1 1.5 0.2 1.8 2.1 0.0 0.0 0.0 11.7 1.7 28.2 21.8 3.1 0.5 0.0 0.0 3.8 0.0 0.0 0.8 0.0 1.7 0.0 3.2 0.4 0.0 0.1 3.3 5.4 0.0 0.0 0.0 0.0 19.6 0.9 0.1 1.8 2.8 0.0 8.1 0.0 4.0 1.8 0.3 0.0 0.0 0.0 0.9 0.0 0.2 4.3 2.6 0.0 0.0 0.6 13.7 2.7 0.0 0.0 0.0 0.1 6.7 0.0 0.5 ZSCAN16 "dJ265C24.3, FLJ22191, ZNF392, ZNF435" ENSG00000196812 "Zinc finger and SCAN domain containing 16" Q9H4T2 6 28124609-28130082 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 69.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007290 Supported Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 45: Intestine - Brush border" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA007290: AB_1080721" "unprognostic (1.50e-1)" "prognostic favorable (5.73e-4)" "unprognostic (3.29e-2)" "unprognostic (8.93e-2)" "unprognostic (3.05e-3)" "unprognostic (1.00e-2)" "unprognostic (3.07e-2)" "prognostic favorable (3.19e-4)" "unprognostic (1.23e-2)" "prognostic favorable (1.14e-5)" "unprognostic (2.50e-1)" "unprognostic (1.98e-1)" "unprognostic (2.50e-1)" "unprognostic (1.55e-2)" "unprognostic (2.14e-1)" "unprognostic (3.37e-3)" "prognostic favorable (3.41e-5)" 3.2 3.9 5.3 5.5 6.4 3.2 7.0 7.7 7.6 3.9 5.2 7.1 8.6 3.9 7.1 3.6 4.1 4.0 3.0 5.6 6.6 5.4 4.4 4.9 8.3 6.4 5.9 2.5 4.9 6.9 3.2 2.2 6.4 4.7 9.0 7.2 6.6 5.8 3.2 6.9 8.4 4.7 5.5 7.4 7.0 2.2 6.1 8.0 4.6 2.7 9.1 4.2 2.7 9.1 0.1 8.8 11.1 8.2 3.0 0.7 9.1 3.0 6.4 7.8 8.4 6.1 5.7 8.8 8.0 2.8 5.4 6.8 7.8 4.4 7.4 12.8 10.8 9.1 7.4 8.7 4.8 6.8 7.4 1.0 7.3 6.6 3.6 8.3 14.7 0.2 1.3 7.3 2.1 10.0 0.0 10.7 2.3 7.4 5.3 10.9 8.4 12.2 9.3 12.6 15.0 16.5 1.5 9.2 10.9 7.2 12.2 3.2 4.6 2.9 6.7 4.4 7.9 3.7 12.5 2.4 1.3 3.4 1.6 69.0 8.6 10.2 13.8 11.8 17.7 19.3 12.0 10.6 9.0 14.6 14.5 11.8 15.6 17.7 11.6 19.6 14.7 8.6 5.3 6.4 7.7 7.6 5.6 6.6 6.4 5.9 6.4 5.5 6.1 9.1 5.6 6.4 2.6 0.3 5.6 1.8 0.8 4.9 1.2 3.8 5.2 5.6 1.6 10.0 7.5 7.3 4.2 2.2 12.6 4.7 5.9 12.8 3.3 4.2 0.8 4.0 1.8 8.2 1.4 12.6 1.2 1.4 4.6 3.3 2.5 4.8 4.2 2.0 2.1 1.7 1.1 6.0 14.2 3.8 1.3 1.5 0.6 4.3 1.8 1.0 6.1 5.6 11.3 3.5 3.7 9.6 6.1 3.4 4.2 1.3 10.3 8.3 7.7 6.6 0.0 1.7 3.7 1.7 6.3 2.7 1.3 1.8 6.1 2.2 7.0 1.1 ZSWIM2 "MEX, MGC33890, ZZZ2" ENSG00000163012 "Zinc finger SWIM-type containing 2" Q8NEG5 2 186827475-186849208 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 9.3" "Cell type enhanced" "Detected in some" "Early spermatids: 61.1;Late spermatids: 18.6;Spermatocytes: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 61.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 18.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0