Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCD1 "adrenoleukodystrophy, ALD, ALDP, AMN" ENSG00000101986 "ATP binding cassette subfamily D member 1" P33897 X 153724856-153744755 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 19.5;Proximal enterocytes: 39.2;Syncytiotrophoblasts: 27.4" "Cancer enhanced" "Detected in all" "melanoma: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 69.7;PC-3: 50.0;SK-BR-3: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035214 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA035214: " "unprognostic (1.90e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-3)" "unprognostic (5.57e-3)" "unprognostic (8.81e-3)" "unprognostic (1.54e-1)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (6.14e-3)" "unprognostic (3.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.17e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.57e-1)" "unprognostic (4.23e-2)" 14.6 33.3 3.1 5.4 3.9 4.7 12.5 3.4 3.8 7.5 2.2 14.7 10.6 33.2 1.7 3.7 9.3 3.4 11.9 2.9 3.4 7.0 13.3 7.6 3.9 4.4 3.6 5.4 11.9 2.1 10.0 4.7 4.8 9.9 1.8 0.5 6.2 5.6 20.5 4.4 17.4 4.8 3.1 13.8 7.2 19.0 5.5 4.3 6.0 4.6 1.7 11.9 6.1 4.2 13.2 4.0 2.6 11.2 7.4 3.2 34.3 6.3 6.8 4.2 7.4 2.6 7.1 3.5 69.7 8.6 11.3 1.7 1.6 1.4 0.5 11.8 2.1 10.3 42.1 34.1 9.8 6.4 22.4 6.2 1.7 4.8 0.4 4.4 6.7 4.7 6.0 12.4 5.9 4.7 4.5 6.1 3.3 3.2 50.0 7.8 6.2 5.7 3.2 1.4 2.8 11.5 16.4 49.2 26.4 3.0 3.7 10.8 7.9 5.5 7.4 14.3 7.0 12.2 5.7 8.4 6.9 21.7 7.8 0.4 3.2 2.5 0.8 3.0 4.0 1.0 1.0 1.2 2.7 0.7 1.1 0.8 1.7 0.7 2.8 1.7 0.3 2.5 3.1 3.9 3.4 3.8 2.9 3.4 4.4 3.6 4.8 3.1 5.5 4.2 5.0 0.0 1.1 3.6 3.8 3.2 1.6 1.6 0.6 2.2 2.7 2.8 2.4 2.8 2.2 3.7 2.1 12.2 4.8 9.5 0.0 3.8 0.7 2.0 3.5 3.4 6.0 3.6 0.5 6.9 19.5 4.5 3.6 4.0 0.0 6.9 5.7 6.8 12.6 8.4 0.9 5.0 2.0 15.9 8.4 2.7 4.1 12.3 1.8 0.0 5.9 2.4 0.0 0.0 1.2 5.0 2.1 5.7 2.4 0.8 39.2 2.8 1.2 0.7 6.6 2.3 2.8 3.8 4.8 0.8 1.3 27.4 4.0 7.8 5.5 1.4 ABCD2 "ALDL1, ALDR, ALDRP" ENSG00000173208 "ATP binding cassette subfamily D member 2" Q9UBJ2 12 39550033-39619803 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.7;brain: 8.9" "Cell type enhanced" "Detected in some" "Astrocytes: 71.5;Bipolar cells: 57.2;Excitatory neurons: 33.2;Inhibitory neurons: 34.2" "Cancer enriched" "Detected in single" 7 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in single" 4 "T-cells: 4.2" "Group enriched" "Detected in some" 6 "ASC diff: 11.6;HDLM-2: 16.9;Karpas-707: 29.0;SH-SY5Y: 17.3;U-266/70: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.26e-3)" "unprognostic (4.06e-4)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (2.06e-1)" "unprognostic (7.31e-5)" "unprognostic (3.42e-2)" "unprognostic (2.90e-2)" "unprognostic (8.06e-3)" "unprognostic (3.43e-2)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-4)" "unprognostic (5.04e-2)" "unprognostic (8.04e-2)" "unprognostic (1.13e-1)" "unprognostic (6.74e-2)" 15.7 1.7 1.5 1.7 2.2 0.2 2.8 8.9 5.2 5.3 0.0 0.7 0.5 2.7 0.2 0.4 2.7 0.5 4.2 2.1 2.1 0.5 0.1 0.5 2.8 2.2 3.3 0.1 0.1 0.0 0.5 0.0 2.4 0.4 0.7 5.9 2.6 0.6 0.1 0.1 0.7 2.6 1.3 1.6 0.7 0.2 3.6 1.4 0.2 0.3 1.6 0.9 0.6 1.4 0.0 0.0 0.1 0.0 11.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 16.9 0.0 0.1 0.0 0.0 0.6 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 9.8 1.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 1.2 0.5 2.8 3.7 0.1 0.3 3.2 4.2 0.1 0.9 0.0 0.6 3.6 1.2 1.5 2.2 8.9 5.2 2.1 2.1 2.2 3.3 2.4 1.3 3.6 1.4 0.4 0.0 0.0 71.5 2.6 0.0 0.0 0.0 0.0 57.2 0.3 0.3 10.9 0.0 0.0 0.0 6.2 0.0 3.8 0.1 0.0 0.0 0.3 0.2 0.5 0.2 0.0 0.0 33.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.1 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.5 1.1 2.2 0.0 13.0 1.3 0.0 0.0 0.7 5.9 0.0 0.0 0.9 2.4 2.3 0.0 0.4 2.5 0.2 0.1 0.0 0.0 0.0 7.8 0.6 0.1 0.0 ABHD15 ENSG00000168792 "Abhydrolase domain containing 15" Q6UXT9 17 29560547-29567037 "Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 26.2" "Cell type enhanced" "Detected in many" "dendritic cells: 79.4;Hepatocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;MAIT T-cell: 6.6;NK-cell: 10.8;plasmacytoid DC: 23.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA014470 Approved Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA014470: AB_1852993" "unprognostic (1.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.38e-1)" "unprognostic (8.60e-3)" "unprognostic (1.91e-1)" "unprognostic (1.62e-1)" "unprognostic (4.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.85e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-3)" "unprognostic (3.00e-2)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (1.71e-1)" "unprognostic (3.46e-1)" "unprognostic (5.45e-2)" 19.2 3.8 3.6 6.2 4.0 8.2 10.6 3.8 3.3 4.6 3.8 7.3 11.2 4.5 3.3 4.7 4.7 5.2 4.9 3.1 4.1 8.9 26.2 6.0 9.1 4.9 4.2 2.9 8.1 7.9 9.1 4.5 4.7 4.7 6.5 1.6 5.1 3.8 2.6 4.6 11.2 4.0 4.2 9.9 8.3 1.8 4.3 4.6 5.8 3.8 8.1 5.6 4.6 4.9 5.8 22.1 2.7 7.7 29.0 12.6 11.3 7.8 8.6 7.6 6.9 5.1 2.9 8.6 5.6 8.4 13.4 15.6 9.7 3.3 4.2 26.5 7.3 3.5 11.0 6.5 8.8 9.0 15.4 9.4 8.9 7.3 1.4 5.6 5.6 5.0 4.6 8.0 4.1 7.8 8.5 10.4 0.6 19.5 6.5 19.7 10.5 20.0 13.7 8.8 1.9 3.1 11.7 5.2 3.1 2.9 13.2 20.5 6.9 4.4 5.5 11.1 7.0 13.3 9.6 4.4 8.8 5.6 9.6 18.3 0.6 2.8 2.6 0.3 6.6 1.4 1.4 2.2 1.5 2.5 0.4 1.3 0.6 10.8 0.2 23.6 1.2 1.1 3.6 4.0 3.8 3.3 3.1 4.1 4.9 4.2 4.7 4.2 4.3 4.9 2.4 3.2 4.1 2.6 11.7 1.3 1.1 2.5 2.2 0.1 3.8 2.4 3.0 2.8 4.3 7.3 0.0 1.5 79.4 12.0 0.0 3.0 0.3 4.7 3.1 2.9 7.2 7.0 0.3 7.6 1.4 4.0 2.0 5.1 2.5 2.9 4.2 30.2 7.2 1.7 0.5 6.1 2.0 6.7 8.4 0.7 4.7 9.5 5.4 2.8 5.6 1.1 15.5 0.5 1.2 5.6 2.5 4.5 5.2 1.5 17.7 5.6 5.2 0.9 0.0 3.5 1.9 0.8 0.6 2.0 2.4 0.3 11.8 4.5 7.4 1.2 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 67.8;neutrophil: 42.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favorable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favorable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 38.8 12.5 6.7 8.5 8.6 39.6 27.9 10.5 8.9 9.8 6.0 12.3 9.9 5.7 4.1 31.1 5.1 11.6 13.4 6.8 7.4 12.0 21.7 16.4 3.4 9.2 8.2 4.6 16.0 12.2 5.6 10.2 9.1 7.1 7.5 6.3 27.4 8.4 15.0 38.0 10.5 9.3 9.3 9.4 12.1 10.8 8.4 6.8 15.5 18.5 7.9 16.7 16.9 11.9 18.9 6.8 8.2 9.7 32.0 12.8 17.1 77.4 27.1 18.8 14.9 9.4 6.4 16.2 10.9 23.2 15.8 5.8 16.5 18.5 22.6 58.4 13.2 36.6 24.4 7.5 15.7 9.2 13.2 13.0 64.6 31.3 28.5 18.8 33.3 10.8 23.9 14.2 46.9 11.0 7.6 6.9 22.8 16.7 20.4 3.1 24.1 8.6 27.9 40.4 10.6 13.6 36.9 20.5 9.8 9.8 18.9 8.9 19.3 18.1 13.6 35.0 34.5 11.1 34.0 7.7 20.3 17.3 16.0 67.8 14.7 9.5 2.3 7.9 1.7 3.5 1.7 2.7 6.8 4.0 1.6 2.5 42.5 2.0 5.7 1.9 4.8 5.3 6.7 8.6 10.5 8.9 6.8 7.4 9.2 8.2 9.1 9.3 8.4 11.9 117.5 25.6 51.8 12.7 44.8 39.9 27.5 25.9 88.8 11.9 149.9 116.2 10.3 14.3 49.6 27.6 27.1 16.7 80.3 65.0 33.2 57.5 19.5 47.5 49.0 34.6 36.2 69.0 24.1 61.5 24.9 53.7 67.8 114.0 16.5 8.8 18.2 12.7 18.0 3.3 24.1 23.7 34.6 44.1 17.4 17.1 5.3 79.8 7.2 11.2 35.9 11.0 12.3 18.1 28.8 75.2 49.8 5.7 41.8 25.5 98.5 39.8 19.1 17.4 0.0 32.0 46.4 47.3 41.9 111.7 40.9 205.4 42.6 15.2 21.9 71.6 ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 ACACB "ACC2, ACCB, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116595-109268226 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 183.3;skeletal muscle: 173.2" "Cell type enhanced" "Detected in many" "Adipocytes: 128.7;Astrocytes: 136.8;Hepatocytes: 216.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 17.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.5" "Cell line enriched" "Detected in many" 18 "ASC diff: 222.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA006554 Enhanced "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA006554: AB_1844495" "unprognostic (2.24e-1)" "unprognostic (4.66e-1)" "unprognostic (3.97e-2)" "unprognostic (4.54e-6)" "unprognostic (2.82e-1)" "unprognostic (1.59e-2)" "unprognostic (8.62e-3)" "unprognostic (5.81e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.63e-2)" "prognostic favorable (1.15e-5)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-3)" "unprognostic (2.58e-2)" 183.3 19.8 19.6 3.3 21.7 3.6 100.5 7.6 11.4 12.9 26.9 37.2 8.4 12.0 3.5 10.6 12.1 10.9 35.4 10.1 11.2 12.6 54.3 6.7 3.8 12.7 19.4 14.3 19.2 17.9 11.2 2.5 11.6 11.8 8.2 1.7 12.5 11.7 173.2 9.5 15.5 9.4 6.7 7.8 18.6 4.9 19.1 4.5 18.1 61.5 3.0 23.0 11.5 13.2 0.9 5.7 3.6 6.9 222.6 1.7 2.6 0.9 1.5 1.0 0.6 4.1 1.1 2.9 1.6 1.2 2.4 4.8 3.0 1.5 0.6 3.8 5.3 6.6 6.2 4.3 1.0 5.7 1.6 2.6 1.5 2.3 0.6 1.7 0.5 4.9 0.7 0.3 0.7 1.7 4.1 5.3 3.9 0.4 12.4 2.2 4.8 1.5 1.8 2.0 2.3 5.4 5.9 2.8 3.4 1.5 2.6 5.9 0.4 2.2 1.3 2.5 1.9 8.8 5.3 4.0 5.3 4.5 1.7 4.6 0.4 17.5 1.1 0.1 0.6 2.2 1.0 0.3 0.2 3.0 1.8 0.9 0.7 0.1 0.2 0.3 0.6 0.1 19.6 21.7 7.6 11.4 10.1 11.2 12.7 19.4 11.6 6.7 19.1 13.2 128.7 6.4 1.1 136.8 3.7 2.3 2.6 1.0 3.4 3.1 32.5 5.0 35.3 25.8 1.7 23.9 0.0 0.6 2.4 13.9 1.9 2.1 34.3 3.3 3.4 26.0 10.2 25.7 5.1 4.0 0.5 16.0 18.3 1.3 1.3 20.0 41.4 216.5 1.7 23.5 6.4 9.6 0.0 12.6 2.4 36.4 29.2 3.7 5.4 28.1 1.2 5.2 2.1 29.7 25.8 2.7 7.3 50.4 2.5 0.9 17.9 6.5 2.3 4.1 6.6 29.3 12.0 2.3 3.0 2.5 1.6 0.1 3.5 21.8 11.8 1.1 ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187126-210225447 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.0;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.9;Early spermatids: 85.6;Late spermatids: 69.4;Leydig cells: 46.9;Peritubular cells: 46.6;Proximal tubular cells: 31.5" "Group enriched" "Detected in many" 8 "liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;RPTEC TERT1: 2.6;SuSa: 2.3;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "HPA011990: AB_1844465" "unprognostic (6.29e-3)" "unprognostic (7.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (7.66e-3)" "unprognostic (3.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.99e-1)" "prognostic favorable (1.58e-11)" "unprognostic (4.22e-3)" "unprognostic (1.18e-4)" "unprognostic (8.81e-3)" "unprognostic (1.06e-1)" 11.9 1.1 0.8 0.1 0.8 0.0 8.0 0.7 1.1 3.4 0.9 0.5 0.0 0.7 1.1 0.5 4.0 0.6 3.1 0.7 1.2 19.8 28.0 10.1 0.0 0.8 0.8 12.7 28.4 4.5 2.9 1.0 0.8 20.6 0.1 0.0 6.8 4.8 9.5 2.8 0.4 0.1 0.8 0.0 5.6 3.1 0.7 1.5 23.7 5.0 0.0 1.0 3.8 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.6 0.5 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.1 0.7 1.2 0.8 0.8 0.8 0.8 0.7 0.9 0.2 28.9 70.9 1.0 0.0 0.6 1.4 1.1 1.2 0.2 1.3 0.5 1.1 8.6 7.6 22.0 2.1 8.8 0.0 0.0 15.6 4.0 85.6 7.1 0.4 0.2 0.0 0.0 0.2 11.9 0.3 4.9 3.6 5.9 2.5 0.8 0.7 23.0 0.5 0.0 13.3 0.0 0.0 0.3 0.4 69.4 46.9 0.4 0.0 4.7 0.0 0.2 0.0 7.5 0.3 3.9 0.0 46.6 0.0 8.2 0.0 31.5 2.4 0.2 0.0 7.6 13.7 0.7 0.7 0.7 1.0 6.3 0.4 0.1 0.0 0.7 ACADS "ACAD3, SCAD" ENSG00000122971 "Acyl-CoA dehydrogenase short chain" P16219 12 120725774-120740008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 245.5;skeletal muscle: 158.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 303.1;Hepatocytes: 203.3;Paneth cells: 185.7;Proximal enterocytes: 435.0;Undifferentiated cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004799, CAB019284, HPA022271" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" Mitochondria "CAB019284: , HPA004799: AB_1844471, HPA022271: AB_1844472" "unprognostic (7.14e-2)" "unprognostic (3.03e-3)" "unprognostic (8.15e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.11e-3)" "unprognostic (5.75e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (2.69e-2)" "unprognostic (4.04e-2)" "prognostic favorable (3.33e-6)" "unprognostic (1.23e-2)" "unprognostic (1.81e-1)" "unprognostic (1.21e-1)" "prognostic favorable (6.34e-5)" 50.3 52.7 13.3 11.1 15.4 14.3 40.9 13.6 16.6 11.2 13.7 74.0 84.8 10.2 0.9 14.1 10.2 8.5 90.5 12.3 13.8 51.9 245.5 13.4 6.4 14.6 14.2 8.6 33.1 4.7 9.2 7.5 13.1 13.9 21.3 0.9 19.2 7.2 158.2 13.7 73.2 5.8 14.0 31.6 34.5 20.3 16.0 6.6 21.9 79.7 3.4 18.0 12.7 14.8 3.2 11.4 0.6 9.7 12.9 5.1 11.1 4.7 4.6 6.0 4.5 8.9 8.0 0.3 11.9 3.9 2.7 5.2 6.6 2.1 0.8 16.7 8.2 8.2 3.6 19.3 9.3 0.7 36.0 15.4 3.1 2.6 0.2 1.8 6.1 20.6 6.9 0.1 2.7 6.8 11.7 19.2 2.0 10.6 4.6 8.6 4.2 2.2 11.3 18.2 1.1 6.0 9.7 0.0 15.8 0.9 7.7 13.1 6.9 0.2 4.7 4.5 0.9 15.3 9.3 4.1 10.2 7.0 4.1 8.3 15.3 7.5 13.7 16.3 9.3 6.3 12.2 14.2 13.2 8.9 15.3 14.4 1.4 19.9 10.2 11.0 14.7 12.8 13.3 15.4 13.6 16.6 12.3 13.8 14.6 14.2 13.1 14.0 16.0 14.8 18.8 12.8 13.7 10.1 6.7 6.6 9.5 21.1 4.0 1.0 25.0 14.9 44.0 27.1 13.0 18.4 0.0 78.8 9.8 303.1 50.9 35.2 23.5 12.8 8.2 13.4 45.6 38.5 2.3 32.6 31.3 18.1 28.5 10.8 19.1 12.8 19.2 203.3 55.1 1.7 2.8 105.3 20.3 21.0 8.9 36.5 21.5 15.3 17.8 0.0 26.1 13.6 18.6 3.0 3.6 26.7 185.7 18.0 7.9 8.3 435.0 94.8 7.3 0.6 6.6 13.2 12.7 41.5 8.1 9.4 4.5 75.5 11.9 140.6 185.9 12.7 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 508.4;Distal tubular cells: 698.5;Hepatocytes: 663.4;Proximal tubular cells: 1484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 420.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 135.4 151.3 45.2 24.3 45.3 38.4 56.9 47.1 60.1 41.0 91.8 96.3 103.9 44.0 34.1 45.0 39.1 25.6 289.4 42.7 46.8 622.7 969.5 43.7 28.2 44.8 45.2 64.7 110.6 95.9 30.9 24.7 45.2 45.6 85.6 26.2 104.1 60.2 461.1 45.3 53.2 57.1 46.7 29.3 81.9 66.3 45.6 19.1 65.5 410.8 29.7 44.1 34.6 47.7 76.9 57.7 48.2 139.3 155.9 138.7 25.1 71.7 78.8 77.7 91.7 168.1 77.3 41.3 116.8 83.6 119.7 78.1 142.3 70.3 83.3 84.9 114.6 117.4 64.6 163.9 107.6 112.9 64.9 124.6 77.1 69.2 127.4 91.5 85.0 92.3 172.1 61.8 128.6 45.8 57.4 122.4 48.2 103.1 135.0 88.1 96.9 420.4 114.7 50.4 75.7 88.1 111.6 152.7 83.0 37.0 132.2 97.6 87.4 83.2 44.5 73.5 88.8 18.9 57.8 77.7 37.6 233.1 59.6 1.4 17.1 4.7 25.3 25.5 29.9 29.2 28.8 30.0 33.5 13.8 25.5 22.4 1.8 13.4 27.8 11.3 35.7 23.4 45.2 45.3 47.1 60.1 42.7 46.8 44.8 45.2 45.2 46.7 45.6 47.7 50.5 54.5 91.8 17.9 37.2 43.1 52.2 48.9 23.9 30.1 34.6 29.6 508.4 78.6 33.5 104.8 27.1 39.9 29.2 125.0 698.5 43.1 345.7 62.2 42.1 62.5 30.0 74.7 35.1 60.5 41.5 57.1 29.0 25.7 27.8 48.6 99.2 663.4 97.9 38.7 37.8 38.5 97.6 73.6 27.8 65.3 66.5 39.1 58.7 30.0 50.1 39.1 25.7 22.6 26.5 33.8 93.8 82.4 52.7 27.8 51.4 1484.0 101.8 28.8 65.7 54.2 69.2 172.7 27.2 39.2 48.4 25.2 38.1 61.6 84.5 24.4 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 374.2;Proximal tubular cells: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 88.8 81.6 154.2 38.6 152.2 32.0 52.4 153.0 190.0 39.5 160.1 94.4 162.9 42.0 26.1 60.4 53.6 36.5 567.7 155.2 153.1 138.9 73.9 40.7 40.5 146.1 145.3 30.8 53.8 233.8 33.6 30.5 147.8 41.2 69.6 46.9 72.0 49.5 660.4 45.5 158.5 43.7 152.5 44.7 110.2 35.1 186.3 38.0 53.7 695.8 43.3 52.5 42.4 159.6 47.2 55.8 56.5 116.3 101.2 69.8 78.7 43.7 60.9 79.0 71.9 81.2 63.5 115.7 72.2 70.6 60.3 109.8 108.8 88.3 42.8 75.8 80.2 51.0 73.7 95.0 86.7 147.8 77.8 120.8 64.4 78.9 83.2 61.7 81.2 61.5 72.9 118.4 65.4 91.7 73.7 47.9 37.0 282.6 115.1 102.3 37.8 162.1 106.8 97.3 37.8 33.9 112.2 128.7 82.0 44.9 74.9 74.7 55.5 60.0 68.7 50.2 45.0 64.7 92.1 80.6 102.0 64.0 66.5 10.3 52.9 18.1 32.0 76.4 29.3 49.4 25.5 34.9 69.0 46.4 29.2 30.8 9.0 39.4 97.1 24.0 41.2 58.6 154.2 152.2 153.0 190.0 155.2 153.1 146.1 145.3 147.8 152.5 186.3 159.6 26.3 25.6 31.8 45.4 49.4 18.7 54.5 102.7 31.3 60.6 28.0 23.2 9.1 64.3 63.5 60.7 81.3 100.3 33.3 190.8 131.0 58.3 14.5 37.2 17.7 26.1 53.2 30.3 28.8 42.6 60.0 24.0 77.5 37.1 40.6 56.7 20.7 64.6 91.5 53.8 34.0 99.1 89.5 35.5 26.4 8.9 24.2 39.2 35.6 7.5 68.3 73.9 34.0 12.1 20.9 43.9 103.5 27.8 63.2 34.4 374.2 285.7 59.2 73.5 59.2 28.6 38.4 26.4 38.2 35.8 16.1 193.2 30.7 54.4 113.6 64.9 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 26.4;Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.6;MCF7: 14.1;SK-BR-3: 27.9;T-47d: 69.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 4.9 1.4 3.7 1.1 3.7 0.6 4.6 4.2 4.3 3.9 2.4 3.0 4.3 0.8 2.6 1.5 0.9 0.9 0.9 3.6 2.9 15.0 16.8 3.6 1.3 3.1 2.7 0.9 1.5 1.0 0.4 1.8 3.3 1.4 3.4 0.8 1.7 1.8 0.6 0.6 3.3 1.5 2.5 1.5 2.0 2.2 2.9 1.0 1.3 0.6 1.3 1.2 0.9 3.2 10.7 2.9 0.3 0.1 1.3 0.6 0.0 0.6 0.0 0.7 1.2 0.3 17.6 0.0 0.6 1.0 0.0 1.1 0.0 0.1 0.1 5.8 0.1 0.0 3.5 0.0 2.0 0.0 9.5 0.8 1.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.6 14.1 0.3 1.9 0.9 3.7 2.8 0.0 0.0 0.0 0.4 5.2 1.5 0.3 6.9 27.9 2.1 0.1 69.7 10.5 0.2 0.0 6.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 11.5 0.0 1.4 14.7 0.6 7.3 2.1 6.9 8.4 0.4 3.3 4.0 8.5 0.0 7.2 0.2 0.9 7.2 5.3 3.7 3.7 4.2 4.3 3.6 2.9 3.1 2.7 3.3 2.5 2.9 3.2 0.4 0.0 2.7 1.0 1.0 0.3 1.1 3.8 1.2 0.2 5.5 4.2 1.7 7.2 2.8 11.0 0.0 15.9 3.6 8.3 15.6 4.2 1.8 4.1 1.1 0.5 0.0 0.0 1.4 9.2 13.8 1.5 3.1 5.6 5.7 4.1 0.0 26.4 11.2 1.7 0.8 3.2 8.2 3.0 0.3 5.3 0.3 2.1 0.0 1.9 1.0 0.7 11.3 0.5 0.3 6.2 2.6 0.4 1.5 1.1 15.7 59.8 2.9 0.5 0.0 1.5 1.1 3.2 15.8 2.6 0.3 4.5 5.1 0.4 2.6 1.3 ACOX1 PALMCOX ENSG00000161533 "Acyl-CoA oxidase 1" Q15067 17 75941507-75979177 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 191.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 199.8;Hepatocytes: 287.4;Proximal enterocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 77.2;neutrophil: 113.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 113.7" "Cell line enhanced" "Detected in all" "BEWO: 96.9;RT4: 129.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021094, HPA021192, HPA021195, HPA028759" Approved Approved Nucleoli,Peroxisomes NA NA 96000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" Peroxisomes Nucleoli "CAB021094: AB_10261667, HPA021192: AB_1844527, HPA021195: AB_1844528, HPA028759: AB_10601352" "unprognostic (7.47e-2)" "unprognostic (3.69e-1)" "unprognostic (1.25e-3)" "unprognostic (1.36e-1)" "unprognostic (7.49e-2)" "unprognostic (8.14e-2)" "unprognostic (3.75e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "prognostic favorable (5.25e-7)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.72e-1)" "unprognostic (4.46e-2)" 37.8 18.1 16.1 10.6 18.2 8.8 17.1 17.4 15.1 11.0 21.3 40.9 62.5 9.3 9.8 30.4 9.9 14.9 23.0 14.3 17.5 40.3 191.5 13.6 6.2 16.6 17.9 9.5 39.7 18.8 12.6 17.3 15.9 18.4 27.1 16.1 15.4 11.8 30.1 24.8 51.4 11.1 17.5 10.5 27.4 9.3 20.6 8.3 17.0 29.2 12.1 19.5 12.7 18.9 16.3 24.5 7.2 9.9 34.0 14.4 96.9 11.8 11.3 12.9 14.8 16.4 24.0 9.1 14.0 17.9 12.5 9.9 28.7 12.4 19.2 10.0 9.5 10.9 13.1 47.2 19.4 9.7 7.8 24.0 9.4 15.7 9.2 13.1 32.3 13.6 12.3 8.9 14.0 45.3 26.3 7.0 4.9 36.8 19.8 13.4 21.3 10.2 20.7 129.1 8.7 12.6 30.6 46.5 11.4 21.2 32.6 11.3 20.9 18.2 13.4 15.2 11.5 14.4 11.0 4.0 10.0 9.7 11.4 77.2 18.3 5.2 6.9 14.2 8.2 5.4 6.6 8.8 10.3 4.5 7.2 7.1 113.7 7.2 9.4 9.4 9.3 8.0 16.1 18.2 17.4 15.1 14.3 17.5 16.6 17.9 15.9 17.5 20.6 18.9 28.0 28.9 25.0 25.1 10.8 13.5 15.9 26.1 21.1 27.4 19.4 13.5 47.4 51.5 23.4 23.9 22.9 37.7 12.1 199.8 21.5 22.9 11.6 18.1 16.7 18.8 34.4 21.5 17.8 40.6 46.5 19.8 88.7 24.1 17.1 21.4 21.8 287.4 25.4 18.5 18.8 44.5 24.4 35.4 14.1 7.1 29.8 23.7 14.2 15.0 36.3 61.9 9.2 22.1 18.2 34.2 100.0 47.0 18.3 24.0 238.7 107.8 17.4 28.4 0.0 18.4 17.2 5.5 11.0 28.5 30.3 43.2 13.2 17.1 41.9 31.7 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 276.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 237.8" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 5.3;ASC TERT1: 11.5;HSkMC: 13.8;U-87 MG: 8.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 25.5 2.5 7.1 0.6 5.2 0.6 10.7 4.7 5.0 2.8 3.0 3.7 0.8 1.2 7.1 1.0 1.7 2.3 3.3 5.5 7.9 25.4 276.6 2.1 1.9 6.3 6.8 0.8 0.6 1.0 0.5 1.4 6.8 0.6 1.2 0.5 0.9 0.9 13.9 2.3 1.9 1.0 6.7 4.6 3.4 0.9 8.2 0.7 4.2 1.7 0.7 1.1 2.2 8.2 0.0 0.0 0.1 0.1 5.3 11.5 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 13.8 0.0 0.8 0.1 0.2 0.0 0.0 0.1 0.5 1.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 8.5 0.1 0.0 0.1 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 7.1 5.2 4.7 5.0 5.5 7.9 6.3 6.8 6.8 6.7 8.2 8.2 0.4 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.5 0.5 0.0 0.3 1.2 0.0 13.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 6.1 237.8 3.7 0.0 0.2 0.0 0.0 11.7 1.5 0.8 9.3 3.5 0.0 7.5 1.3 0.9 0.0 1.5 0.1 0.0 0.0 6.0 0.0 0.2 0.0 52.1 0.0 0.1 0.0 11.3 0.3 0.2 0.3 0.1 0.6 0.0 0.7 0.9 0.1 0.2 ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 117.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 137.7;Hepatocytes: 138.9;Intestinal goblet cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.3" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.3;monocytes: 21.8" "Cell line enhanced" "Detected in many" "HBEC3-KT: 132.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved NA NA 16000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" 69.3 23.7 4.0 10.7 9.3 7.5 27.2 6.8 7.8 15.1 6.0 54.6 64.2 13.7 34.3 18.6 22.1 10.7 49.8 3.3 6.4 22.0 46.9 23.2 4.0 12.1 5.9 13.0 14.8 19.6 3.8 17.2 12.7 12.2 32.9 5.3 38.1 16.2 117.3 17.1 46.8 11.3 5.1 8.1 37.7 10.6 7.2 4.0 9.6 99.2 7.0 9.3 11.9 16.3 32.8 11.6 17.1 10.7 69.5 59.1 25.5 14.5 32.4 13.9 21.7 27.3 40.6 0.1 18.6 24.1 50.2 26.0 20.1 132.4 9.5 0.1 7.1 37.2 6.6 18.5 46.2 6.6 28.1 50.3 34.2 24.8 34.5 27.8 27.7 4.2 22.0 7.1 15.8 13.3 2.4 18.8 3.3 27.6 44.1 15.9 20.3 83.4 62.5 9.0 2.9 14.5 24.7 49.1 32.1 21.2 19.6 24.4 23.5 12.3 7.8 12.4 7.9 24.0 19.7 9.1 32.3 9.3 9.1 34.3 21.8 6.6 1.2 13.3 1.2 0.7 3.0 1.3 22.6 1.1 5.3 2.9 12.2 0.7 6.4 4.2 2.0 9.2 4.0 9.3 6.8 7.8 3.3 6.4 12.1 5.9 12.7 5.1 7.2 16.3 8.8 12.8 41.1 17.6 4.2 7.8 9.4 13.5 10.2 6.4 27.6 10.9 82.2 20.0 16.6 11.0 6.2 15.5 3.7 137.7 11.7 20.8 9.0 8.0 8.2 13.5 7.8 29.0 18.5 33.7 11.2 11.4 58.1 13.0 9.5 35.3 13.6 138.9 16.4 8.4 18.2 100.6 18.3 17.9 13.9 7.2 11.5 15.6 14.2 17.8 19.4 9.1 1.0 5.5 86.5 23.4 66.4 4.5 14.6 11.2 70.4 60.5 7.6 4.1 13.1 7.2 9.8 32.1 20.3 12.3 10.9 20.9 5.1 7.8 75.1 13.0 ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261210 "Enzymes, Metabolic proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 46.5;Astrocytes: 167.8;Early spermatids: 52.9;Hepatocytes: 53.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "basophil: 7.0;neutrophil: 2.2" "Lineage enriched" "Detected in single" 70 "granulocytes: 7.0" "Cell line enhanced" "Detected in many" "ASC diff: 14.3;ASC TERT1: 16.1;Hep G2: 42.6;hTERT-RPE1: 14.0;RH-30: 19.1;SK-BR-3: 18.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA039353: AB_2676460, HPA047956: AB_2680223, HPA061517: AB_2684549" "unprognostic (8.59e-2)" "unprognostic (9.29e-4)" "unprognostic (1.47e-1)" "unprognostic (9.37e-3)" "unprognostic (2.46e-2)" "unprognostic (2.21e-1)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (7.79e-2)" "prognostic favorable (0.00e+0)" "unprognostic (6.16e-4)" "unprognostic (1.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-4)" 22.7 14.5 5.2 1.5 5.1 0.1 7.3 5.2 5.3 8.3 9.3 2.2 0.7 9.1 12.1 1.5 8.0 8.1 6.8 4.7 4.9 25.9 40.0 6.4 1.5 5.5 6.4 16.7 2.0 13.7 4.4 4.0 5.2 5.7 1.0 4.8 12.1 5.5 3.5 1.7 1.5 6.3 4.9 2.1 1.4 2.3 6.5 1.1 8.8 5.7 1.1 2.8 5.0 5.5 0.0 0.2 3.4 0.0 14.3 16.1 0.1 2.2 11.0 1.7 1.9 0.4 0.1 0.0 0.0 5.0 5.2 0.1 0.0 0.0 1.0 0.0 2.2 0.0 0.0 42.6 4.8 0.1 0.0 10.8 0.0 0.5 0.0 14.0 0.4 0.0 0.0 0.0 7.8 1.0 0.1 0.2 4.8 0.0 0.0 0.0 19.1 2.7 0.1 0.1 3.1 0.0 0.0 18.0 0.1 7.1 7.9 0.5 0.0 2.8 2.7 0.2 1.2 0.1 0.1 0.1 3.5 0.0 3.4 7.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 5.2 5.1 5.2 5.3 4.7 4.9 5.5 6.4 5.2 4.9 6.5 5.5 1.3 22.4 46.5 167.8 0.2 0.9 9.5 0.0 2.2 37.8 5.6 3.0 21.8 14.3 3.2 12.9 4.2 1.5 0.1 0.1 5.9 6.4 52.9 3.9 14.8 1.5 0.0 0.0 1.5 2.9 0.8 12.1 0.0 2.7 0.0 8.8 1.8 53.6 0.7 28.6 1.6 0.1 0.0 3.2 0.6 9.4 23.9 0.8 0.0 35.6 0.1 16.4 0.0 16.6 0.7 0.1 0.1 23.7 0.0 3.0 1.1 31.7 3.7 5.3 6.6 18.6 9.9 4.6 0.6 0.4 0.1 0.5 0.6 13.2 1.2 3.7 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 31.3;brain: 10.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.2;Leydig cells: 31.7;Oligodendrocytes: 55.8;Proximal enterocytes: 17.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 10.9;HDLM-2: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 29.7" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 31.3 2.5 3.2 0.6 6.3 0.1 6.2 1.3 3.5 0.5 0.0 4.1 4.1 0.1 0.3 0.2 0.1 0.3 0.4 6.4 10.2 0.4 2.2 0.2 0.5 1.4 1.9 3.6 1.5 0.0 2.2 0.1 1.3 0.2 3.0 0.4 0.8 0.3 0.8 0.3 3.4 0.2 0.9 0.1 2.1 0.4 6.6 0.2 0.2 0.3 0.3 0.1 0.2 3.8 1.5 0.0 0.0 0.1 10.9 0.3 0.2 0.3 0.3 0.1 0.3 1.7 0.2 0.0 0.1 0.9 0.7 0.0 0.1 0.0 0.2 5.1 0.7 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.1 0.6 1.9 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.2 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.2 6.3 1.3 3.5 6.4 10.2 1.4 1.9 1.3 0.9 6.6 3.8 0.5 0.0 1.1 14.7 1.4 0.6 0.7 0.9 1.8 0.8 0.9 0.3 1.9 0.0 0.9 0.0 0.0 0.2 0.3 14.3 0.0 0.2 1.9 0.4 4.9 0.7 7.8 0.0 26.2 0.2 0.8 0.9 2.6 0.5 0.0 0.4 1.1 5.9 0.1 0.0 11.0 9.2 2.0 0.0 1.3 2.9 31.7 0.1 3.6 3.7 4.3 1.8 0.0 3.5 55.8 0.4 7.6 9.1 2.9 1.8 17.7 1.1 0.2 0.3 0.0 0.6 0.8 0.4 2.4 0.7 1.4 0.3 2.5 0.4 13.5 0.5 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 ADAP2 CENTA2 ENSG00000184060 "ArfGAP with dual PH domains 2" Q9NPF8 17 30906344-30959322 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.2;Hofbauer cells: 195.8;Kupffer cells: 186.8;Macrophages: 97.2;monocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 22.4;intermediate monocyte: 34.3;myeloid DC: 12.6;non-classical monocyte: 43.5" "Group enriched" "Detected in many" 9 "dendritic cells: 12.6;monocytes: 43.5" "Cell line enhanced" "Detected in some" "EFO-21: 7.0;HAP1: 17.6;HEK 293: 11.0;RPMI-8226: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (4.00e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.25e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.38e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-2)" 11.3 8.9 6.6 15.3 7.6 3.9 4.6 6.7 8.5 2.9 9.1 6.5 5.7 3.2 2.9 3.1 3.3 9.2 4.4 6.2 8.0 5.1 11.0 9.8 9.8 12.1 9.6 1.9 3.1 9.1 1.9 19.7 10.4 2.4 8.0 1.3 3.1 3.1 1.8 6.7 5.6 9.8 8.6 22.5 4.3 2.0 14.7 4.6 3.2 6.4 6.7 9.0 2.2 12.9 0.1 1.7 0.2 0.4 0.4 0.5 4.5 0.1 0.0 0.3 0.1 0.7 0.7 1.0 7.0 0.1 0.2 0.1 17.6 0.2 0.3 0.4 11.0 0.0 1.0 2.0 2.9 0.4 1.9 1.1 4.4 0.9 0.6 0.2 0.0 0.0 0.2 1.8 0.6 3.6 0.1 0.3 0.1 0.4 0.1 0.3 0.0 22.9 2.4 2.3 0.3 0.1 0.3 0.2 0.1 1.5 3.8 2.9 0.0 0.4 1.1 0.8 0.1 0.8 0.5 1.0 0.4 0.4 0.0 0.2 22.4 0.0 0.0 34.3 0.0 3.0 0.1 0.1 12.6 2.1 0.1 0.1 1.7 0.0 43.5 0.4 0.4 6.6 6.6 7.6 6.7 8.5 6.2 8.0 12.1 9.6 10.4 8.6 14.7 12.9 5.4 3.2 5.2 2.6 8.6 2.0 0.5 0.5 2.2 0.8 0.7 2.4 1.5 1.5 0.9 0.0 2.1 23.5 0.2 3.1 0.0 0.3 0.6 1.7 0.6 7.8 0.0 0.4 1.1 1.4 86.2 1.9 0.0 1.2 3.8 0.4 4.6 1.6 195.8 0.0 1.4 0.6 0.0 186.8 13.1 0.5 0.9 97.2 0.0 40.3 88.2 0.6 2.1 2.0 1.3 0.9 0.9 0.4 2.6 0.9 0.3 8.3 2.2 2.8 39.5 1.2 26.5 0.9 0.9 1.0 6.5 26.4 1.6 0.2 0.3 0.6 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.7;heart muscle: 105.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.5;Inhibitory neurons: 44.0;Oligodendrocytes: 89.7;Paneth cells: 59.6;Peritubular cells: 73.7;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 15.5;RPMI-8226: 2.7;RPTEC TERT1: 5.2" "Region enriched" "Detected in all" 5 "basal ganglia: 388.0" "Region enriched" "Detected in all" 6 "basal ganglia: 155.9" "HPA017730, HPA077682" Uncertain Enhanced "Intermediate filaments" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "HPA017730: AB_1844595, HPA077682: AB_2686851" "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favorable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" 18.9 3.3 25.5 4.9 97.7 0.0 10.6 13.9 43.9 9.8 0.0 35.1 5.2 14.7 5.7 18.8 12.7 10.0 105.2 25.8 15.9 12.8 3.3 4.1 2.3 20.5 18.3 13.2 7.5 0.8 14.3 6.1 17.4 19.8 5.6 4.5 4.0 21.5 2.7 2.6 13.0 18.2 10.8 6.5 21.2 8.2 34.4 1.3 1.9 5.8 3.0 23.2 7.8 30.1 0.0 0.6 1.3 0.1 0.1 0.1 0.3 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.2 2.3 0.5 0.6 0.0 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 15.5 0.0 0.0 0.8 0.0 0.1 0.0 0.3 2.7 5.2 0.5 1.8 1.6 0.0 0.5 0.1 1.7 0.0 0.1 0.0 0.1 1.2 0.1 0.2 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.5 97.7 13.9 43.9 25.8 15.9 20.5 18.3 17.4 10.8 34.4 30.1 0.3 0.0 0.0 8.1 0.1 0.3 0.1 0.2 0.0 21.8 0.4 5.8 75.5 8.6 0.0 7.3 0.0 1.4 0.0 2.6 0.0 15.9 0.9 1.5 7.1 1.8 0.0 0.0 34.0 6.9 4.0 5.2 0.0 4.0 0.0 4.6 3.9 0.1 0.3 0.0 44.0 0.3 0.0 0.0 0.3 3.0 20.5 0.1 0.0 6.5 1.0 1.0 0.0 19.1 89.7 0.4 59.6 73.7 0.0 0.1 0.3 0.8 0.0 2.2 65.7 0.6 21.4 0.8 6.3 0.2 0.9 12.4 0.2 1.0 2.0 0.1 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "adipose tissue: 898.8;breast: 248.9" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 672 "ASC diff: 312.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" NA NA 8360000000 910000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB046467: AB_1078104, HPA051767: AB_2681598" "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" 898.8 8.9 0.1 2.4 0.1 0.2 248.9 0.2 0.1 0.0 0.0 7.7 0.1 0.1 0.0 1.2 0.1 7.6 6.5 0.0 0.0 0.8 0.1 0.1 1.3 0.1 0.0 0.0 6.2 0.1 0.1 0.0 0.1 0.3 6.1 0.1 18.8 0.0 2.3 6.6 8.5 1.2 0.0 0.0 3.9 0.1 0.1 2.2 2.9 20.2 0.0 2.4 0.9 0.3 0.0 0.0 0.0 0.1 312.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADIPOR2 "ACDCR2, PAQR2" ENSG00000006831 "Adiponectin receptor 2" Q86V24 12 1688574-1788674 "Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 321.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043737 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA043737: AB_10964205" "unprognostic (1.52e-1)" "unprognostic (2.11e-1)" "unprognostic (2.44e-1)" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (1.34e-1)" "unprognostic (5.33e-2)" "unprognostic (7.66e-3)" "unprognostic (4.86e-2)" "unprognostic (1.61e-1)" "unprognostic (5.34e-3)" "unprognostic (2.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.15e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (5.85e-2)" 55.1 72.3 36.6 10.6 49.8 9.6 44.2 46.4 48.7 25.8 28.3 32.2 22.2 24.4 8.1 45.2 23.3 9.7 33.3 35.3 40.6 22.4 79.6 44.6 9.8 50.9 46.9 25.1 31.1 16.9 26.1 13.0 49.5 20.7 17.7 13.1 22.2 11.9 42.9 31.9 32.7 12.0 41.6 19.9 44.7 27.7 44.5 12.8 28.0 19.9 12.6 21.4 29.3 67.0 34.3 28.0 23.1 21.4 21.4 25.6 30.9 24.6 28.4 31.5 44.5 42.1 51.6 24.1 7.8 23.0 56.7 26.1 34.7 35.8 44.9 62.7 28.7 47.3 22.7 30.3 21.2 36.1 29.3 22.6 35.5 39.8 45.6 28.7 23.1 25.8 31.7 50.9 23.7 48.8 23.6 32.8 46.3 28.4 14.8 19.5 43.7 18.3 31.4 19.9 6.9 16.4 22.7 43.8 51.5 39.7 24.6 46.5 23.2 17.8 37.5 28.6 36.2 12.3 16.5 39.5 21.7 32.3 24.7 0.7 0.7 1.8 0.9 0.7 0.7 0.5 0.5 0.8 0.5 0.5 0.6 0.7 0.9 0.6 0.6 0.9 0.7 0.3 36.6 49.8 46.4 48.7 35.3 40.6 50.9 46.9 49.5 41.6 44.5 67.0 81.5 12.8 32.4 39.2 21.8 23.7 25.0 26.6 22.8 11.3 29.9 20.3 22.3 31.5 36.6 14.7 18.8 13.9 32.4 91.4 11.7 22.6 56.3 17.8 15.4 41.1 37.5 38.1 35.7 31.4 42.2 21.1 61.7 30.2 36.3 28.8 28.9 113.4 18.2 18.5 41.3 49.0 32.6 27.3 18.9 77.0 15.8 32.6 26.6 124.6 27.0 32.5 27.8 32.2 321.0 39.6 49.4 22.6 30.2 27.8 41.5 10.8 21.7 16.0 6.6 21.3 25.7 45.0 42.2 29.7 34.4 29.3 26.1 39.6 33.5 29.8 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 AGPAT2 "BSCL, LPAAT-beta" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687457 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 369.3;liver: 445.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 688.9;Late spermatids: 387.3;Paneth cells: 670.7;Proximal enterocytes: 1298.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 186.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019544 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" 369.3 38.3 11.4 11.8 9.3 34.2 259.9 8.8 15.9 32.1 13.5 83.2 111.4 26.4 9.6 85.6 29.7 15.7 84.9 9.4 12.6 80.2 445.0 60.9 9.2 11.8 12.3 17.7 129.6 18.4 41.5 8.0 11.3 34.3 12.2 0.9 48.1 12.8 37.4 51.1 119.4 6.7 11.4 39.2 52.0 24.1 13.9 5.5 46.9 10.0 5.3 35.5 36.6 9.6 55.0 75.2 8.9 41.4 63.3 19.8 37.3 35.5 28.5 24.1 18.5 86.0 105.7 17.8 77.8 21.0 38.6 145.1 12.7 22.2 2.8 186.9 57.3 26.5 30.3 19.2 42.6 28.1 62.1 19.0 30.9 20.9 11.0 20.9 12.5 23.6 32.7 2.9 10.4 98.5 1.9 87.4 22.5 101.0 135.0 41.0 31.3 100.3 28.5 33.9 19.5 31.4 45.8 47.6 60.3 6.8 30.6 109.3 24.7 31.5 32.1 10.4 23.0 4.4 0.4 11.8 0.4 59.7 32.1 20.1 88.8 111.8 6.8 83.5 6.5 12.8 5.8 7.9 47.8 22.7 4.6 5.5 61.1 7.2 75.7 65.6 8.1 35.2 11.4 9.3 8.8 15.9 9.4 12.6 11.8 12.3 11.3 11.4 13.9 9.6 25.9 16.0 64.4 0.7 20.2 45.2 60.0 64.0 22.8 3.5 23.4 22.4 39.6 87.2 45.3 73.5 0.0 7.3 30.8 688.9 54.8 155.2 136.4 50.4 17.4 27.9 35.8 8.0 1.9 219.5 37.1 30.1 81.6 63.8 13.4 31.4 31.1 228.0 131.2 40.4 2.6 197.3 126.1 53.4 57.4 387.3 26.8 57.6 136.9 4.7 48.8 14.6 23.7 0.0 0.3 169.5 670.7 20.3 13.4 93.5 1298.3 41.9 46.3 3.8 46.0 15.3 29.8 1.8 27.2 47.5 81.3 6.8 26.6 16.4 207.7 196.2 AIFM2 "AMID, FLJ14497, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 173.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cytosol" "HPA028961: AB_2672844, HPA042309: AB_10796575, HPA075576: " "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (4.29e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.26e-3)" "unprognostic (2.57e-2)" "unprognostic (7.95e-3)" "unprognostic (2.80e-1)" "unprognostic (5.31e-2)" "unprognostic (8.90e-2)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.49e-1)" "unprognostic (4.59e-3)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.92e-4)" 39.6 13.5 7.5 6.3 8.1 1.9 31.2 7.3 8.0 6.9 8.6 12.9 9.3 7.8 9.0 13.3 6.8 5.0 17.0 6.9 7.7 10.4 21.9 9.3 5.1 8.2 7.3 7.9 5.0 3.2 5.6 4.1 6.9 9.9 7.1 2.4 7.6 7.7 9.8 5.6 11.5 5.0 6.2 7.7 9.9 3.9 8.3 2.4 14.6 7.3 3.6 12.0 6.3 6.5 26.5 45.2 1.1 11.3 26.2 9.8 0.3 10.4 25.5 21.0 23.6 35.3 49.8 3.8 25.8 14.5 27.5 27.9 12.7 3.8 5.9 50.8 1.9 0.2 27.3 173.3 56.1 0.3 6.4 13.3 8.4 33.8 7.2 13.2 9.5 1.7 20.5 21.9 11.0 33.5 1.2 1.3 4.5 21.2 14.6 0.8 4.2 12.4 11.4 19.2 3.6 0.8 19.1 16.6 29.8 1.8 0.7 7.2 12.0 0.5 25.3 15.6 30.8 16.2 32.7 7.3 14.0 0.9 13.9 1.0 0.5 0.5 1.8 0.5 1.5 1.7 0.6 1.5 0.4 1.5 0.8 1.3 0.5 4.0 0.5 0.2 1.3 0.7 7.5 8.1 7.3 8.0 6.9 7.7 8.2 7.3 6.9 6.2 8.3 6.5 11.6 6.4 14.1 7.2 5.0 2.3 15.0 8.4 2.8 5.7 5.5 4.7 13.8 8.6 10.5 18.4 0.0 13.9 1.4 53.1 3.9 40.7 24.1 6.0 7.7 4.8 12.0 7.0 8.2 21.9 3.0 11.2 14.3 6.2 11.4 22.3 1.8 25.0 10.2 1.7 5.2 7.1 14.2 3.3 3.3 47.0 5.3 6.7 8.8 4.7 34.4 4.8 1.0 5.5 3.5 40.8 22.7 4.5 17.0 14.6 28.7 22.6 9.5 2.1 19.7 11.8 12.8 6.2 3.9 5.1 1.4 18.6 3.8 8.8 13.7 20.4 AKNAD1 "C1orf62, MGC26989" ENSG00000162641 "AKNA domain containing 1" Q5T1N1 1 108815898-108963484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.8" "Cell type enriched" "Detected in some" 4 "Early spermatids: 80.6" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.1;hTCEpi: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030270, HPA030271, HPA030272" Uncertain Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Microtubules, Cytokinetic bridge" "HPA030270: AB_10610980, HPA030271: AB_10600873, HPA030272: AB_10601342" "unprognostic (4.93e-2)" "unprognostic (1.72e-1)" "unprognostic (5.52e-2)" "unprognostic (2.00e-3)" "unprognostic (7.22e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-5)" "unprognostic (8.15e-2)" "unprognostic (5.95e-2)" "unprognostic (2.83e-2)" "unprognostic (1.89e-1)" "unprognostic (2.24e-1)" "unprognostic (3.00e-8)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "unprognostic (5.75e-2)" "unprognostic (8.22e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.7 0.0 0.0 1.6 0.0 1.5 0.1 0.0 1.8 2.5 0.5 0.9 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.2 80.6 0.3 5.1 1.4 0.0 0.0 1.0 0.2 0.8 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.7 0.0 0.0 0.3 17.8 2.5 0.1 1.8 0.0 0.0 0.4 0.0 3.5 3.1 0.2 0.0 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.9 0.6 1.4 0.1 0.1 0.7 0.1 0.7 0.5 0.0 AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 341.5;liver: 481.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 141.7;Club cells: 128.8;Gastric mucus-secreting cells: 133.5;Hepatocytes: 397.4;Urothelial cells: 271.9" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "A549: 2054.8;ASC diff: 2439.5;Hep G2: 3926.2;OE19: 2684.9;RT4: 1178.9" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: AB_2685966" "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" 341.5 20.8 9.8 10.0 11.6 1.0 205.6 10.7 12.9 17.4 8.1 37.1 29.6 5.6 3.3 202.5 8.6 98.1 83.8 7.2 16.6 43.0 481.9 23.5 2.1 18.7 13.7 10.4 11.8 1.1 8.1 0.8 17.1 11.7 13.3 15.2 116.5 12.9 286.9 42.5 33.7 9.2 11.5 2.1 137.0 11.8 16.8 4.4 38.3 36.5 9.3 253.9 47.0 9.7 0.0 2054.8 2.4 214.1 2439.5 83.4 0.1 0.7 8.6 0.9 2.0 8.1 0.2 0.4 11.5 14.2 10.0 57.8 0.2 10.7 1.2 0.6 0.2 0.7 516.4 3926.2 4.6 0.4 0.9 218.3 126.4 10.5 10.4 0.7 0.9 0.3 81.9 0.3 20.4 3.3 0.2 0.0 0.7 2684.9 0.8 0.3 0.6 34.6 19.0 1178.9 1.2 0.4 21.2 0.3 0.1 0.4 0.5 4.0 8.6 5.1 1.8 74.6 0.8 0.6 0.6 0.3 25.9 30.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 11.6 10.7 12.9 7.2 16.6 18.7 13.7 17.1 11.5 16.8 9.7 15.2 12.8 2.8 0.0 0.9 11.9 9.5 141.7 20.5 1.9 0.8 1.4 5.5 102.9 128.8 0.0 0.0 0.0 0.0 10.3 0.0 18.3 17.3 0.7 0.5 7.5 1.8 8.0 2.6 103.3 0.1 44.2 133.5 0.8 0.0 0.1 10.8 397.4 0.1 3.3 4.2 5.4 46.8 12.0 7.8 7.8 79.2 1.0 8.8 19.7 0.6 39.6 0.0 5.5 0.3 90.0 6.6 78.6 0.8 23.7 15.9 3.6 40.3 3.0 0.0 5.3 13.9 0.2 0.3 112.9 13.5 0.0 1.3 0.4 8.5 271.9 AL845331.1 ENSG00000259916 "Putative aquaporin-7-like protein 3" 2 94588522-94604573 "Metabolic proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "adipose tissue: 7.5;breast: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "ASC diff: 1.9" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (8.07e-3)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (9.15e-3)" "unprognostic (6.22e-2)" "unprognostic (4.66e-2)" 7.5 0.1 0.0 0.0 0.5 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 369.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 633.3;Proximal tubular cells: 197.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.5;Hep G2: 78.1;Karpas-707: 82.0;RPMI-8226: 45.0;RT4: 219.1;U-266/70: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 3000000 "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favorable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" 76.4 37.2 53.4 2.0 63.2 0.4 28.8 55.9 63.6 15.6 37.7 10.1 0.2 7.2 2.5 6.6 16.0 2.3 26.5 47.5 56.2 116.6 369.7 3.1 0.3 56.7 52.9 45.3 44.3 15.1 4.5 0.0 53.0 14.6 5.4 8.7 88.6 6.9 90.7 3.5 5.6 2.0 48.4 0.4 9.5 15.0 53.9 3.7 2.6 59.9 4.6 28.3 6.4 46.0 1.3 0.0 0.0 0.0 36.5 0.0 0.4 0.3 1.5 0.4 0.6 0.0 3.2 2.6 10.2 0.0 2.1 0.4 0.6 1.5 0.7 0.0 0.2 0.1 0.3 78.1 10.6 10.6 0.2 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 82.0 1.6 0.0 0.0 0.2 0.3 1.1 0.0 0.1 0.2 45.0 0.7 219.1 0.4 0.3 1.3 10.6 0.0 0.6 0.1 0.0 0.3 1.4 6.2 0.0 0.1 44.8 14.8 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 63.2 55.9 63.6 47.5 56.2 56.7 52.9 53.0 48.4 53.9 46.0 0.8 0.0 6.0 92.7 4.6 0.1 53.5 9.1 1.8 0.2 14.4 2.2 16.1 38.6 44.0 12.9 0.0 0.0 0.1 7.2 72.4 2.9 22.3 57.2 5.2 4.6 1.2 34.7 0.6 5.6 0.2 9.1 0.0 3.6 27.8 12.4 17.2 633.3 0.1 0.0 3.0 17.6 2.0 24.5 1.9 35.0 26.4 9.3 3.6 3.7 0.0 40.0 0.0 11.1 0.2 2.2 0.4 22.6 0.0 12.2 0.8 197.4 32.2 1.4 6.6 10.5 5.3 1.6 4.3 1.7 0.0 0.1 2.8 0.9 5.6 61.7 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Cell line enhanced" "Detected in many" "ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 303.8 102.4 139.7 39.8 146.1 29.2 77.2 136.5 163.5 25.0 123.3 73.3 73.7 30.1 21.3 73.6 32.3 37.4 111.3 132.2 139.7 177.7 857.7 111.6 18.7 140.7 144.9 42.0 23.3 2.6 23.3 7.0 141.1 34.6 72.3 29.2 32.4 29.5 130.8 127.9 74.8 30.2 143.0 20.6 101.5 13.0 151.8 27.1 30.8 165.7 52.9 50.0 29.0 144.5 8.8 13.1 18.7 31.9 86.8 13.0 60.9 9.3 16.8 4.3 3.1 23.5 12.1 0.5 45.3 20.8 11.9 16.2 0.1 4.6 2.7 0.6 6.1 0.7 8.4 64.7 97.0 0.9 0.9 23.9 22.6 14.8 0.3 17.7 26.9 0.9 17.9 3.0 4.1 0.5 1.0 23.4 24.8 152.2 2.1 0.6 0.4 1.9 31.4 0.6 7.5 23.1 22.8 201.0 0.2 33.7 20.3 92.1 1.1 0.4 16.5 0.6 0.4 5.5 3.0 25.7 22.0 0.8 0.4 6.5 212.0 51.1 0.7 93.0 0.9 6.2 0.3 0.7 213.2 5.2 0.7 0.5 10.7 3.4 25.4 70.6 0.5 123.5 139.7 146.1 136.5 163.5 132.2 139.7 140.7 144.9 141.1 143.0 151.8 144.5 27.7 147.4 242.7 51.2 22.6 60.0 205.2 311.1 80.8 78.7 35.0 23.7 378.9 165.8 243.1 66.2 18.8 62.4 48.6 260.3 399.2 127.5 4.3 27.8 24.5 66.2 55.2 42.1 11.7 218.0 127.5 103.1 200.3 47.7 30.9 29.0 139.6 857.0 129.2 35.3 18.2 231.0 101.7 278.5 124.1 10.6 79.9 189.3 35.6 26.2 940.8 130.2 8.2 14.1 6.8 130.2 366.5 149.0 12.5 84.4 384.3 882.0 89.4 42.6 46.0 46.0 67.6 3.0 3.9 105.1 124.7 42.1 13.1 81.0 272.6 150.4 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 200.4;liver: 436.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 83.7;SK-BR-3: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 58000 "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: " "unprognostic (1.17e-1)" "prognostic favorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 70.8 16.1 73.9 3.9 88.9 11.7 21.6 73.8 95.9 12.6 106.5 6.8 1.6 9.8 4.7 36.3 8.3 5.5 33.0 68.2 73.8 200.4 436.6 6.2 3.4 72.9 82.8 7.3 4.6 23.0 9.7 13.2 70.0 29.5 2.7 6.5 9.1 27.1 74.2 19.2 4.7 7.1 65.6 7.5 12.5 3.2 92.4 11.7 7.1 74.8 4.2 19.3 16.8 66.1 12.7 17.8 9.5 29.2 40.0 5.7 25.2 13.1 7.1 11.8 9.5 13.7 8.9 8.8 16.6 15.6 5.7 34.0 16.7 35.4 4.5 4.8 15.9 5.9 5.0 83.7 12.6 4.4 15.1 15.6 19.2 6.5 6.6 9.0 13.5 14.0 21.0 5.7 8.1 32.3 4.3 20.2 4.7 26.0 10.1 27.9 8.4 10.0 12.1 32.0 19.6 7.6 21.9 85.0 16.1 14.7 38.7 6.3 11.3 10.2 14.0 12.2 4.5 7.1 17.9 2.5 3.4 33.7 13.5 0.0 2.7 1.5 0.6 3.6 0.5 0.8 0.3 0.8 4.4 0.7 0.2 0.5 0.3 0.1 2.0 1.5 0.6 1.5 73.9 88.9 73.8 95.9 68.2 73.8 72.9 82.8 70.0 65.6 92.4 66.1 2.6 0.0 2.8 27.1 4.3 7.5 17.9 12.5 17.6 3.7 9.8 8.5 20.9 34.3 2.9 46.0 10.4 78.0 2.0 2.0 46.9 6.5 0.5 1.1 1.7 3.1 2.4 32.2 1.2 0.9 12.6 3.2 7.7 3.9 4.5 2.1 15.4 385.1 13.8 20.2 1.6 3.6 6.1 17.2 1.4 0.6 1.2 4.7 3.6 1.9 10.9 14.0 1.0 5.5 1.3 2.5 1.8 2.6 4.4 12.0 0.3 279.4 1.7 4.8 6.6 2.6 4.7 2.2 3.9 21.7 5.4 86.6 2.6 4.5 4.0 9.5 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Cell line enhanced" "Detected in all" "T-47d: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 38.7 14.7 58.6 4.8 66.0 3.3 14.4 58.8 59.3 17.3 61.4 15.2 26.6 11.4 9.8 9.8 12.8 9.4 40.3 51.0 54.0 379.1 367.1 9.4 5.1 63.3 54.0 28.3 23.4 37.0 6.6 7.6 55.6 25.4 15.8 15.2 19.8 16.1 27.5 6.2 23.4 9.0 56.4 5.4 24.0 17.1 69.8 5.7 28.3 34.8 5.3 11.4 7.0 62.6 8.9 7.8 11.0 23.5 39.3 19.2 17.5 6.3 11.8 6.8 11.5 17.3 10.2 10.5 13.6 13.5 5.3 4.8 24.9 7.0 14.5 9.5 3.5 5.1 8.0 19.2 45.0 2.7 2.4 28.2 12.0 8.7 20.7 17.0 12.0 23.7 8.1 14.7 4.6 36.2 7.6 4.0 8.7 32.6 5.2 15.1 11.2 14.6 9.2 5.8 4.4 7.0 21.0 21.9 5.7 18.0 57.5 9.6 3.8 7.4 9.0 11.7 2.4 9.3 18.9 10.2 9.9 3.2 7.3 29.1 6.2 43.2 6.9 4.8 10.6 7.2 7.8 8.4 9.2 6.1 9.9 7.0 2.4 9.7 4.2 5.3 6.1 4.9 58.6 66.0 58.8 59.3 51.0 54.0 63.3 54.0 55.6 56.4 69.8 62.6 15.4 38.5 60.4 24.5 11.8 9.2 26.8 10.0 20.5 20.6 28.4 18.9 81.4 67.2 22.9 66.2 4.2 31.0 7.1 18.9 201.5 11.6 23.4 26.2 27.5 27.0 16.9 28.6 5.5 3.1 14.8 25.9 34.7 90.2 7.6 27.1 87.4 523.6 17.7 11.8 10.0 39.3 8.2 26.5 8.9 19.0 28.9 13.4 24.9 1.9 15.8 98.5 9.2 12.5 23.4 4.1 16.3 48.2 8.0 27.6 55.3 962.4 15.4 17.0 13.1 25.6 16.9 11.0 4.2 25.2 7.4 30.6 11.0 10.2 35.7 17.2 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 ALPK3 "KIAA1330, MAK, Midori" ENSG00000136383 "Alpha kinase 3" Q96L96 15 84817356-84873479 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 62.7;skeletal muscle: 195.8;tongue: 59.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 64.1;Exocrine glandular cells: 20.5;Skeletal myocytes: 51.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.3;HDLM-2: 10.7;HUVEC TERT2: 15.5;LHCN-M2: 21.2;NTERA-2: 12.9;RH-30: 37.7;THP-1: 9.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA026558 Uncertain Approved Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "HPA026558: AB_1844774" "unprognostic (2.69e-2)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (4.61e-2)" "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.44e-3)" "unprognostic (1.42e-1)" "unprognostic (1.68e-2)" "unprognostic (1.82e-1)" "unprognostic (1.74e-3)" "unprognostic (1.23e-1)" "prognostic favorable (3.95e-7)" "unprognostic (1.76e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (4.87e-2)" 12.5 9.6 1.2 0.9 1.6 0.1 4.4 1.0 2.2 2.2 9.3 7.5 0.6 1.5 5.4 3.0 1.7 1.8 62.7 1.3 3.8 13.5 5.9 5.5 0.6 2.2 3.4 0.8 7.7 11.2 26.1 2.5 4.5 2.4 0.8 2.5 2.6 1.3 195.8 1.0 2.1 3.1 1.6 0.5 5.2 0.9 3.9 0.6 3.6 59.1 0.4 3.6 1.4 1.1 1.8 0.1 0.1 0.2 0.3 0.1 14.3 0.0 0.0 0.0 0.1 0.1 6.3 0.0 0.4 0.0 0.1 1.1 0.0 0.0 0.1 10.7 1.7 1.8 0.3 0.0 0.2 0.0 0.1 1.3 0.2 0.0 0.0 0.1 15.5 0.1 0.0 0.1 21.2 0.9 0.0 0.2 12.9 0.3 0.1 0.0 37.7 0.2 0.0 4.0 0.0 0.2 0.0 2.0 0.1 1.9 0.1 9.6 0.3 0.1 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 1.0 2.2 1.3 3.8 2.2 3.4 4.5 1.6 3.9 1.1 3.3 6.4 2.7 2.6 0.2 0.9 0.1 0.6 1.2 4.1 1.3 0.8 64.1 17.2 2.4 9.2 16.7 0.3 0.2 0.5 0.0 2.9 0.3 11.5 1.0 8.7 9.1 0.0 3.0 20.5 0.7 3.8 0.5 8.9 1.3 8.7 1.8 1.7 10.2 0.0 3.4 0.3 0.0 0.3 12.0 0.0 0.0 5.2 3.6 9.4 4.7 1.0 1.0 0.5 0.3 10.4 1.2 0.0 1.5 0.7 0.1 2.2 4.2 3.4 0.0 51.9 8.4 0.5 3.2 0.2 0.1 0.7 0.5 0.2 0.3 1.6 ANGPTL8 "C19orf80, RIFL, TD26" ENSG00000130173 "Angiopoietin like 8" Q6UXH0 19 11237450-11241943 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Hormone "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 409.8" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 151.2" "Cancer enriched" "Detected in some" 37 "liver cancer: 84.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "Hep G2: 37.0;MCF7: 21.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA042131 Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 836000 350000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" Nucleoplasm "HPA042131: AB_10794413" "unprognostic (2.37e-2)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-2)" "unprognostic (1.17e-1)" "unprognostic (1.00e-1)" "unprognostic (3.73e-1)" "unprognostic (2.80e-1)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" "unprognostic (9.67e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (4.57e-1)" "unprognostic (1.75e-2)" 35.7 0.8 1.1 0.2 1.0 0.1 22.5 0.1 1.7 1.2 0.0 1.4 0.4 0.9 1.6 0.3 0.8 0.4 1.8 0.9 0.6 4.0 409.8 0.4 0.1 0.7 0.6 1.1 0.9 0.0 0.3 0.1 0.5 0.8 0.0 0.1 1.3 0.1 0.8 0.9 1.2 0.1 0.3 0.4 0.7 0.5 1.1 0.0 1.0 0.0 0.0 1.1 1.0 0.9 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 1.3 37.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 21.2 0.0 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.0 0.3 0.0 0.3 0.4 0.9 0.0 0.4 0.6 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.1 1.7 0.9 0.6 0.7 0.6 0.5 0.3 1.1 0.9 0.6 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.4 0.2 0.8 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.3 0.2 0.0 2.7 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 4.6 151.2 0.1 0.0 0.0 0.0 0.0 4.4 0.0 1.9 0.9 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.2 0.0 0.1 ANKRD53 "FLJ12056, FLJ36160" ENSG00000144031 "Ankyrin repeat domain 53" Q8N9V6 2 70978380-70985499 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.5" "Group enriched" "Detected in many" 21 "Early spermatids: 158.6;Late spermatids: 481.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HHSteC: 1.6;HSkMC: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049574 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA049574: AB_2680819" "unprognostic (6.11e-3)" "unprognostic (6.51e-2)" "unprognostic (1.70e-3)" "unprognostic (2.68e-1)" "unprognostic (2.01e-2)" "unprognostic (6.31e-3)" "unprognostic (2.20e-1)" "unprognostic (6.35e-2)" "unprognostic (3.53e-1)" "unprognostic (1.27e-1)" "unprognostic (6.39e-3)" "unprognostic (1.83e-1)" "unprognostic (1.13e-2)" "unprognostic (1.68e-3)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" 7.5 1.7 0.3 0.6 0.2 0.3 6.1 1.5 0.5 1.8 0.0 1.9 0.7 1.8 0.4 0.7 3.0 0.7 1.3 0.3 0.2 0.8 0.6 1.3 0.3 0.8 0.4 4.1 8.2 0.3 3.2 0.3 0.2 2.0 0.2 6.1 4.5 0.6 0.4 0.8 1.7 0.6 0.3 0.8 2.0 27.5 0.1 0.1 3.1 0.3 0.3 1.6 1.6 0.2 0.0 0.0 0.1 0.1 1.0 0.4 0.1 0.1 0.4 0.4 0.4 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.6 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.3 0.2 1.5 0.5 0.3 0.2 0.8 0.4 0.2 0.3 0.1 0.2 1.1 0.0 0.0 0.3 1.1 0.1 1.4 0.5 4.6 1.3 0.3 1.3 0.4 1.5 0.1 0.0 2.1 0.1 1.0 0.0 0.0 1.2 158.6 4.3 0.5 0.7 0.0 0.4 0.4 0.4 1.0 1.9 1.1 2.2 0.0 0.4 1.1 0.2 0.0 1.7 1.2 0.0 0.0 0.0 0.4 481.3 3.4 0.4 0.0 0.0 0.0 4.1 0.0 1.5 0.3 0.5 0.0 3.0 11.7 0.7 0.1 1.5 0.6 15.1 6.6 2.8 1.5 1.5 1.7 0.6 0.0 0.3 0.4 0.1 0.1 0.1 ANXA6 ANX6 ENSG00000197043 "Annexin A6" P08133 5 151100706-151157785 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 343.8;monocytes: 445.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 861.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002462, CAB005077, HPA009650, HPA009977" Enhanced Approved Cytosol NA NA 1800000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005077: AB_630873, HPA002462: AB_1078166, HPA009650: AB_1844867, HPA009977: " "unprognostic (1.74e-1)" "unprognostic (5.85e-2)" "unprognostic (1.03e-1)" "unprognostic (5.81e-2)" "unprognostic (2.44e-1)" "unprognostic (9.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (9.63e-2)" "unprognostic (1.60e-2)" "unprognostic (1.08e-3)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.31e-5)" "unprognostic (6.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (1.38e-3)" 292.9 135.4 98.1 164.2 104.1 109.7 188.3 94.0 150.6 148.9 151.8 196.0 44.5 181.5 105.0 94.7 149.9 108.7 188.7 102.5 123.1 82.6 214.4 131.6 161.8 144.2 109.4 181.7 78.3 29.6 161.9 141.1 146.2 124.9 78.2 133.6 70.3 208.6 331.3 62.7 119.9 300.1 92.3 150.9 111.4 52.5 127.4 160.8 86.7 371.5 176.4 206.5 107.4 104.8 3.0 30.4 212.8 317.1 861.2 417.8 55.1 397.4 526.4 323.5 477.6 106.7 15.6 26.9 138.5 578.6 268.1 0.5 165.9 200.2 300.3 110.5 52.1 15.3 62.1 204.7 295.0 97.6 94.7 508.6 1.5 282.3 42.0 476.9 420.6 197.5 22.0 396.1 737.6 100.4 181.8 151.7 56.2 1.2 92.4 120.4 592.9 31.0 42.2 0.3 12.2 49.3 39.9 282.7 175.6 308.4 488.3 201.1 326.8 296.6 84.2 19.4 107.1 205.4 289.5 4.5 154.5 459.7 46.2 89.7 89.4 82.9 290.4 54.7 190.4 175.4 213.4 263.3 118.3 179.0 145.8 181.6 17.6 261.9 25.0 30.2 190.9 331.7 98.1 104.1 94.0 150.6 102.5 123.1 144.2 109.4 146.2 92.3 127.4 104.8 90.3 16.0 17.3 19.2 146.8 11.0 11.5 2.2 1.8 16.5 30.7 24.0 59.5 12.8 1.1 23.9 6.2 64.3 110.3 0.3 25.4 6.5 56.9 1.8 38.5 45.6 21.4 36.4 36.5 17.8 33.7 105.9 9.2 1.7 57.5 343.8 57.1 147.1 85.4 15.2 36.3 2.4 0.0 41.0 77.8 46.8 123.3 41.2 55.2 10.3 445.2 45.6 187.4 18.6 5.6 12.1 1.2 211.4 120.3 7.3 1.0 48.4 4.7 125.8 230.1 55.3 150.6 2.5 1.5 0.6 8.1 177.2 143.4 149.4 2.5 1.5 AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase copper containing 2" O75106 17 42844580-42850707 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Early spermatids: 29.5" "Cancer enhanced" "Detected in some" "testis cancer: 3.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "ASC diff: 11.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA057779 Uncertain "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "HPA057779: " "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-4)" "unprognostic (1.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (4.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.64e-2)" "unprognostic (2.16e-2)" "unprognostic (8.27e-3)" "unprognostic (4.55e-5)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.47e-4)" 5.8 1.1 1.9 0.6 2.1 0.9 2.6 1.9 3.2 1.3 0.6 1.3 0.3 1.0 0.5 0.7 1.6 0.7 0.7 2.4 1.9 1.2 3.4 2.3 0.5 2.0 1.6 1.1 0.7 0.2 2.0 0.4 2.0 1.5 0.2 1.5 0.6 0.5 1.6 1.3 0.8 0.6 1.1 1.6 0.8 4.8 2.0 0.3 0.9 0.6 0.6 1.8 1.2 1.9 0.2 2.3 0.5 2.5 11.2 1.1 6.0 0.8 0.7 1.6 2.2 1.8 0.2 0.9 1.1 0.2 0.7 1.0 2.2 0.6 3.2 2.0 6.0 0.3 1.3 1.9 0.7 0.3 2.2 1.7 2.0 1.5 2.3 0.4 0.4 3.1 0.6 2.1 0.4 0.3 0.5 0.9 0.8 0.2 0.7 1.1 2.3 1.9 0.3 3.6 0.8 0.5 0.1 0.8 3.4 4.6 0.4 0.2 0.4 1.5 3.2 2.0 1.0 4.6 4.9 0.9 0.4 2.2 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.9 2.1 1.9 3.2 2.4 1.9 2.0 1.6 2.0 1.1 2.0 1.9 1.1 0.0 0.5 1.6 0.3 1.0 0.5 0.1 0.0 0.5 0.9 0.9 0.4 0.0 0.7 0.0 2.1 0.1 0.4 0.0 0.0 0.3 29.5 1.4 0.7 1.4 0.0 0.0 1.8 0.4 0.1 0.2 0.0 2.8 0.0 0.5 0.4 0.7 0.1 0.0 1.2 0.2 0.0 0.3 0.6 5.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.2 0.1 0.0 0.0 1.2 0.1 0.2 0.4 0.8 0.0 0.5 1.0 2.3 2.1 0.4 1.6 0.0 0.2 0.4 0.2 0.6 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 304.3;liver: 1191.0" "Group enriched" "Detected in some" 8 "Hepatocytes: 2967.4;Proximal enterocytes: 1585.9" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 1079.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793" Supported Supported Vesicles,Cytosol "Secreted to blood" NA NA 1490000000000 100000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "CAB016070: AB_626690, HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" 2.7 0.0 0.1 0.2 0.2 0.1 0.9 0.1 0.1 0.7 0.2 0.4 181.4 0.2 0.0 0.1 0.1 0.5 5.2 0.1 0.3 0.3 1191.0 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.1 0.5 304.3 0.2 0.2 0.5 0.3 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1079.8 0.0 0.6 0.1 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 277.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 1.6 3.5 0.0 104.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 52.8 2967.4 0.1 0.0 0.2 30.8 0.0 69.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.5 1.5 0.0 0.0 1585.9 0.6 0.0 0.0 0.0 1.1 0.2 0.5 0.3 0.0 0.0 0.0 3.9 0.9 14.5 0.0 AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 622.6;testis: 222.0" "Group enriched" "Detected in many" 7 "Early spermatids: 1542.9;Late spermatids: 4265.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "OE19: 223.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" 2.9 0.8 2.7 0.1 3.7 0.2 17.1 3.3 2.7 12.9 1.5 0.4 15.3 2.7 0.2 16.5 0.7 2.8 4.0 2.4 2.9 1.9 0.1 7.6 0.0 3.3 3.9 0.2 2.0 3.0 1.2 0.0 3.1 1.3 0.0 1.0 622.6 1.0 0.2 112.7 0.1 0.3 2.6 0.4 52.3 222.0 3.8 0.0 1.6 0.0 0.1 0.3 0.4 2.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.7 223.2 0.0 10.1 0.0 0.0 0.3 0.0 0.2 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.7 3.3 2.7 2.4 2.9 3.3 3.9 3.1 2.6 3.8 2.6 0.5 57.7 3.1 0.0 0.1 1.3 0.5 18.3 0.0 0.8 53.9 48.0 0.3 0.0 56.4 7.3 0.0 0.0 0.1 0.0 0.0 0.1 1542.9 1.5 0.1 1.8 0.0 0.0 0.0 0.2 0.0 1.4 34.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 26.4 0.0 1.6 4265.6 28.6 1.7 295.3 0.0 0.0 53.7 0.0 3.0 0.1 7.2 0.0 19.2 0.3 1.6 0.0 0.0 9.7 1.7 19.7 0.0 1.8 403.9 15.9 1.3 0.9 0.0 0.6 18.7 0.0 0.6 AQP7 "AQP7L, AQP9, AQPap" ENSG00000165269 "Aquaporin 7" O14520 9 33383179-33402682 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 252.7;breast: 104.9;heart muscle: 108.5" "Cell type enhanced" "Detected in many" "Adipocytes: 129.7;Cardiomyocytes: 86.0;Early spermatids: 128.5;Proximal enterocytes: 160.7;Proximal tubular cells: 61.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 43 "ASC diff: 196.0" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.25e-2)" "unprognostic (3.81e-3)" "unprognostic (1.25e-5)" "unprognostic (7.22e-3)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (4.67e-2)" "unprognostic (3.06e-2)" "unprognostic (9.99e-2)" "unprognostic (4.65e-2)" "unprognostic (8.56e-4)" "unprognostic (1.21e-1)" "prognostic favorable (9.21e-8)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" 252.7 5.0 0.9 1.9 1.3 0.0 104.9 4.4 1.4 1.3 0.0 6.6 17.9 1.7 2.9 2.8 5.9 3.4 108.5 0.8 0.7 24.2 23.5 1.2 0.7 4.8 0.7 1.8 3.8 18.3 0.3 0.5 5.8 1.2 4.0 0.3 6.4 2.5 33.8 6.2 26.8 2.5 0.3 1.3 2.8 30.4 1.0 1.0 4.8 51.9 0.2 4.7 2.2 1.2 0.1 1.9 0.2 0.1 196.0 4.5 0.2 0.0 0.0 0.0 0.0 2.2 0.1 0.2 0.1 0.1 0.1 0.3 0.1 1.1 0.0 0.1 0.0 0.1 0.4 2.2 0.2 0.0 0.2 3.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 1.3 4.4 1.4 0.8 0.7 4.8 0.7 5.8 0.3 1.0 1.2 129.7 6.4 7.3 0.3 0.2 1.5 0.3 0.3 0.0 0.0 0.8 1.5 86.0 14.3 0.9 35.0 0.0 0.0 0.6 30.7 5.9 1.9 128.5 9.1 0.2 11.2 0.0 0.0 0.1 0.2 0.3 4.1 0.0 0.7 0.0 0.2 2.9 20.1 0.1 0.0 0.1 9.2 0.0 0.3 0.3 21.4 2.1 1.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.2 22.5 1.9 0.1 0.5 160.7 61.4 7.7 0.0 6.6 1.7 9.6 4.1 0.7 1.3 2.6 0.0 0.3 0.9 4.3 2.1 ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 33.2;Endothelial cells: 28.3;Hepatic stellate cells: 28.5;Horizontal cells: 38.7;Microglial cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 39.4;HUVEC TERT2: 74.3;TIME: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" 11.4 4.1 4.6 5.4 4.7 6.2 10.1 5.2 5.4 9.5 1.5 4.5 3.2 7.5 5.4 3.2 7.8 6.7 14.1 3.3 2.9 7.8 2.1 15.8 2.3 4.1 4.4 3.7 2.5 5.3 5.1 11.9 4.4 7.4 2.6 3.9 3.9 5.8 7.0 2.6 4.6 5.9 3.1 7.3 4.3 1.6 6.3 0.7 8.5 9.2 1.2 7.8 7.3 2.9 11.9 7.5 29.4 0.0 1.8 4.5 0.3 7.0 7.9 7.2 9.2 4.7 0.9 0.1 39.4 2.6 11.7 12.8 5.0 16.8 5.5 0.2 2.1 11.0 12.6 0.1 8.2 0.9 0.4 8.3 7.6 3.9 8.9 20.1 74.3 0.0 0.8 0.1 1.0 0.3 0.0 9.5 17.4 3.9 9.4 0.2 2.3 0.0 0.8 5.4 0.5 24.7 15.1 0.8 12.7 10.6 0.4 2.8 53.3 4.8 10.8 1.3 14.7 0.0 0.1 0.1 12.4 12.6 24.3 0.3 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.1 0.2 4.6 4.7 5.2 5.4 3.3 2.9 4.1 4.4 4.4 3.1 6.3 2.9 33.2 3.2 8.6 0.3 0.3 0.5 1.7 3.1 0.0 6.1 0.9 2.2 5.2 0.0 2.6 1.8 0.0 0.1 1.6 1.3 0.0 1.2 0.0 0.7 2.3 28.3 0.0 0.0 2.4 0.7 0.1 2.2 1.1 1.2 1.3 0.0 28.5 0.3 1.3 38.7 3.2 1.3 2.0 4.4 2.1 0.6 0.3 2.2 0.0 15.0 2.7 3.6 2.1 1.5 0.1 4.6 1.8 1.5 1.6 2.8 0.0 0.1 0.9 0.9 0.0 1.2 3.3 0.5 0.9 0.8 0.4 0.1 1.5 0.4 2.7 3.6 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARL11 "ARLTS1, FLJ33930" ENSG00000152213 "ADP ribosylation factor like GTPase 11" Q969Q4 13 49628507-49633872 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Hofbauer cells: 31.3;Kupffer cells: 34.8;Macrophages: 18.2;monocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 38.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 7.9;HMC-1: 10.7;NB-4: 11.1;THP-1: 14.5;U-698: 6.6;U-937: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040855, HPA040887" Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Intermediate filaments, Cytosol" "HPA040855: AB_10793864, HPA040887: AB_10796229" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (2.82e-1)" "unprognostic (7.86e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.72e-2)" "unprognostic (2.55e-1)" "unprognostic (2.27e-4)" "unprognostic (1.72e-2)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (3.14e-2)" 0.8 0.8 0.5 3.9 0.5 3.5 0.7 0.6 0.7 0.6 0.8 1.0 1.2 0.2 0.2 1.0 0.3 1.1 0.4 0.4 0.6 0.1 0.6 2.2 6.9 1.0 0.7 0.2 0.1 0.3 0.3 1.9 0.8 0.2 1.5 0.1 0.6 0.2 0.3 0.6 1.9 0.7 0.7 4.8 0.6 0.3 1.0 3.7 0.4 0.4 3.9 1.3 0.8 1.2 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 0.6 0.0 5.2 10.7 0.1 0.1 0.0 0.0 0.0 0.4 5.1 0.3 0.1 0.0 1.3 4.9 11.1 0.1 0.0 0.0 5.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 3.5 14.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.6 0.0 6.3 0.0 21.8 15.3 16.3 0.1 17.9 0.2 7.9 0.3 0.3 8.1 10.1 0.8 0.4 38.0 0.8 13.4 8.6 0.3 4.4 0.5 0.5 0.6 0.7 0.4 0.6 1.0 0.7 0.8 0.7 1.0 1.2 0.9 0.0 1.1 0.0 18.2 0.3 0.3 0.2 1.2 0.7 1.0 0.9 0.6 2.8 0.0 0.0 0.0 4.7 3.4 1.7 0.0 0.0 1.7 0.1 0.1 1.2 1.2 6.9 0.0 0.0 5.1 0.3 0.0 0.1 7.6 0.0 1.8 0.6 31.3 0.0 0.0 3.4 0.0 34.8 3.5 1.3 0.3 18.2 0.0 3.7 19.2 0.3 1.0 0.0 0.1 0.1 10.2 0.0 2.9 0.1 4.2 0.1 2.3 0.5 0.0 0.3 0.2 1.5 0.3 4.1 0.0 1.5 1.2 0.5 3.1 0.4 ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444961-130501274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 1284.8;liver: 2037.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 398.7;Hepatocytes: 1062.0;Proximal enterocytes: 618.2;Proximal tubular cells: 1408.9;Urothelial cells: 413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "BJ hTERT+: 893.9;HaCaT: 850.4;hTCEpi: 817.8;RPMI-8226: 1444.5;THP-1: 1061.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020896, HPA020934" Enhanced Supported Nucleoplasm,Cytosol No No 6400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA020896: AB_1845117, HPA020934: AB_1845118" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (8.14e-9)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.92e-3)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (3.14e-1)" "unprognostic (4.72e-3)" 215.0 146.8 29.6 51.3 29.7 0.2 168.2 25.0 31.0 67.0 61.7 157.2 124.5 111.3 124.8 51.1 166.3 110.2 66.5 31.5 38.3 1284.8 2037.7 52.9 7.5 40.2 42.2 57.2 68.4 11.4 45.0 50.6 51.7 56.2 167.9 6.9 119.4 132.6 74.4 131.3 194.8 61.2 28.4 20.0 53.2 35.9 38.4 7.8 92.3 71.4 15.6 288.7 66.6 25.3 124.5 11.9 13.7 23.1 88.4 223.1 43.6 146.2 893.9 28.2 85.5 52.5 34.0 0.4 95.9 300.2 8.2 850.4 59.9 5.2 19.5 21.7 27.1 0.3 18.3 137.3 305.4 18.3 1.6 148.2 817.8 45.4 81.2 0.3 1.1 384.0 5.3 530.6 28.8 619.8 7.2 262.7 19.2 635.9 26.7 1.7 15.4 1444.5 78.8 61.3 342.4 5.8 515.4 534.7 41.5 53.5 366.1 1061.5 0.4 11.3 68.3 2.3 13.0 88.1 91.5 32.1 219.0 137.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 29.6 29.7 25.0 31.0 31.5 38.3 40.2 42.2 51.7 28.4 38.4 25.3 72.1 25.6 28.6 2.6 21.3 70.5 55.7 179.8 53.5 0.1 23.7 17.3 5.4 138.7 104.4 47.8 0.0 178.5 0.4 398.7 133.1 116.5 1.2 4.7 30.5 68.0 12.0 93.7 2.2 110.5 8.9 21.5 20.4 6.2 5.7 55.5 65.7 1062.0 14.7 0.0 8.0 186.8 24.4 40.1 6.5 7.8 31.1 8.0 3.6 7.5 1.6 10.6 0.0 0.0 0.2 70.8 310.4 124.8 11.7 104.0 618.2 1408.9 32.7 0.4 0.0 18.7 13.4 1.4 2.6 23.5 17.5 144.1 11.5 62.0 165.6 413.2 ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 515.9;skeletal muscle: 882.2;tongue: 478.0" "Cell type enhanced" "Detected in some" "Astrocytes: 515.8;Cardiomyocytes: 158.7;Microglial cells: 141.5;Muller glia cells: 73.0;Oligodendrocyte precursor cells: 94.0;Sertoli cells: 85.5" "Cancer enriched" "Detected in many" 18 "glioma: 91.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 51.9;HHSteC: 14.6;RH-30: 16.8;U-87 MG: 10.3" "Low region specificity" "Detected in all" CAB022230 Enhanced NA NA 170000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022230: " "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.16e-2)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.85e-2)" "unprognostic (8.63e-4)" "unprognostic (1.70e-2)" "unprognostic (9.40e-3)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (5.32e-3)" 37.4 4.1 401.5 1.5 480.5 0.0 27.4 419.8 412.8 9.3 164.9 55.8 3.6 5.6 12.5 33.5 14.5 8.0 144.6 337.4 398.5 3.9 1.2 6.4 0.3 429.5 478.8 18.9 1.4 0.3 32.3 3.3 375.3 28.5 8.1 58.5 18.2 28.5 882.2 4.7 15.9 7.8 365.0 1.8 15.7 5.8 515.9 0.6 3.5 478.0 0.5 29.9 9.8 327.7 0.0 0.0 51.9 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 4.6 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 401.5 480.5 419.8 412.8 337.4 398.5 429.5 478.8 375.3 365.0 515.9 327.7 1.4 0.0 0.0 515.8 0.1 0.5 1.6 0.0 0.6 1.3 2.5 0.9 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 1.2 11.1 0.0 0.0 5.5 0.0 0.0 4.8 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 1.3 1.4 28.9 0.5 0.0 141.5 0.5 73.0 0.0 94.0 2.5 0.0 0.0 39.5 0.0 0.8 0.0 0.1 0.1 3.9 85.5 54.9 45.8 0.3 0.2 0.2 0.6 0.1 0.1 5.8 0.0 0.6 ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 63.6;salivary gland: 78.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 16.5;Cytotrophoblasts: 13.4;Distal tubular cells: 31.3;Ionocytes: 57.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SK-BR-3: 55.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favorable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" 0.2 0.0 0.3 0.0 0.4 0.0 4.7 0.1 0.5 3.7 3.1 0.0 0.1 0.1 1.2 4.9 0.0 0.0 0.0 0.6 0.2 63.6 0.0 0.4 0.0 0.3 0.2 0.0 0.1 1.6 0.1 2.5 0.2 0.9 0.0 0.0 78.4 1.5 0.0 10.2 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.4 0.0 0.0 3.7 0.1 0.2 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.6 0.6 1.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 5.0 1.9 0.0 0.1 0.0 0.1 0.1 0.6 0.0 4.5 0.2 0.0 0.0 0.1 55.7 1.9 2.9 0.1 0.0 0.2 0.6 1.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.5 0.6 0.2 0.3 0.2 0.2 0.2 0.3 0.3 0.0 0.0 1.1 0.3 0.0 0.0 1.1 0.9 0.0 0.0 2.5 1.4 0.5 0.0 1.7 16.5 2.1 13.4 0.3 0.0 31.3 0.0 2.2 0.9 0.1 0.1 0.0 0.0 1.4 0.0 0.7 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 57.0 0.0 0.0 2.8 0.3 0.0 7.2 1.0 0.0 0.0 0.0 6.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 4.4 0.1 0.0 0.0 0.1 0.6 0.7 0.0 0.1 5.1 0.2 0.0 0.0 1.3 ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 263.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 284.7;Distal tubular cells: 172.1;Early spermatids: 261.4;Late spermatids: 373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028382: AB_2672574, HPA044950: AB_2679151" "unprognostic (1.34e-1)" "unprognostic (2.97e-3)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (5.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "prognostic favorable (5.33e-7)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" 66.0 89.9 87.5 23.3 94.4 27.4 30.2 97.1 115.2 30.0 102.8 44.9 35.3 22.5 29.4 30.1 27.3 25.8 221.0 82.9 107.7 97.1 95.3 21.9 27.9 85.8 85.6 28.8 41.2 121.5 43.8 32.3 85.3 32.2 48.1 63.9 48.4 29.0 221.0 20.1 35.2 32.3 80.7 21.6 42.1 41.5 90.6 37.8 37.1 263.4 28.5 26.4 20.2 82.2 57.8 46.1 61.1 54.8 65.1 52.3 51.0 42.2 52.6 62.0 49.7 37.2 24.5 34.1 55.2 53.6 54.9 43.6 97.3 54.7 83.1 75.0 76.7 60.2 54.5 65.0 52.4 60.2 3.4 51.4 64.3 66.5 57.7 49.2 39.3 62.8 28.2 65.4 48.0 52.3 89.3 33.3 96.3 49.8 68.8 38.1 16.5 74.3 71.4 45.2 71.8 53.8 71.4 74.9 114.6 70.0 69.3 83.8 34.4 21.1 52.1 43.1 58.5 80.6 78.9 23.2 34.7 23.0 40.6 0.0 1.6 4.1 2.1 2.8 2.7 1.8 2.2 2.5 1.6 1.2 3.1 1.4 1.3 5.6 1.2 1.2 4.5 1.2 87.5 94.4 97.1 115.2 82.9 107.7 85.8 85.6 85.3 80.7 90.6 82.2 12.6 3.2 18.6 31.0 22.3 9.4 21.2 9.7 27.3 34.0 27.8 19.4 284.7 31.5 13.1 31.3 27.1 64.0 14.5 26.7 172.1 22.1 261.4 15.6 15.4 13.2 19.2 31.3 37.1 20.1 30.0 28.5 29.0 15.9 15.9 40.6 10.4 39.8 39.2 47.1 48.5 38.1 16.2 21.6 12.9 373.7 19.0 16.1 24.9 15.9 14.6 39.2 15.5 28.1 33.7 11.3 18.0 26.7 36.3 15.2 30.2 119.1 10.2 29.2 26.3 25.1 28.9 45.2 40.4 34.3 13.5 46.9 19.2 55.1 42.2 21.9 BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 300.9;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 67.8;Astrocytes: 198.2;Excitatory neurons: 131.4;Inhibitory neurons: 62.3;Muller glia cells: 132.4;Oligodendrocyte precursor cells: 125.7" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Cell line enhanced" "Detected in many" "AF22: 51.7;BJ hTERT+: 18.1;SCLC-21H: 27.9;SH-SY5Y: 20.5;U-87 MG: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" 9.3 15.6 196.7 2.1 209.2 3.4 7.0 182.2 226.6 1.6 108.2 3.1 0.9 1.7 0.4 0.7 3.8 1.6 3.1 201.1 206.8 4.3 2.9 7.3 1.4 240.0 237.4 3.3 2.1 0.4 25.9 5.3 219.5 1.1 1.6 19.4 1.0 0.9 2.0 2.0 2.7 1.8 229.2 14.5 2.4 1.3 300.9 0.6 4.5 1.4 0.8 2.5 1.4 205.3 0.5 3.0 51.7 0.5 0.5 14.9 0.0 2.6 18.1 0.1 0.2 0.5 0.1 0.2 0.5 10.1 0.2 0.8 0.9 0.1 0.1 0.1 3.1 0.5 0.8 0.1 1.2 0.0 1.1 3.0 2.9 0.6 0.0 2.7 0.4 0.1 0.0 0.4 0.1 0.4 0.0 0.2 1.3 0.4 1.0 0.2 0.3 1.2 0.0 0.1 27.9 20.5 0.6 0.0 0.1 4.5 0.2 0.3 3.0 16.0 1.0 0.4 1.0 0.0 0.2 0.2 75.7 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 196.7 209.2 182.2 226.6 201.1 206.8 240.0 237.4 219.5 229.2 300.9 205.3 67.8 0.0 1.8 198.2 0.3 5.5 0.7 4.5 0.6 2.1 2.0 1.1 0.8 17.2 5.9 0.0 0.0 0.1 2.1 0.3 7.9 32.0 2.9 15.6 2.3 33.4 17.8 6.1 131.4 25.6 0.1 1.6 0.0 34.0 0.0 0.0 23.6 0.8 0.9 0.0 62.3 3.4 22.4 1.3 6.2 8.7 1.5 2.1 14.2 18.7 4.6 132.4 2.1 125.7 46.1 4.1 1.2 0.0 0.8 0.8 0.1 0.1 21.7 3.3 0.0 2.1 8.1 0.1 0.1 0.3 4.0 0.0 1.3 0.3 0.1 1.1 BANK1 "BANK, FLJ20706" ENSG00000153064 "B cell scaffold protein with ankyrin repeats 1" Q8NDB2 4 101411286-102074812 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.2;lymphoid tissue: 96.4" "Cell type enriched" "Detected in many" 10 "B-cells: 455.9" "Cancer enhanced" "Detected in many" "prostate cancer: 6.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 14 "memory B-cell: 310.4;naive B-cell: 253.0" "Lineage enriched" "Detected in many" 16 "B-cells: 310.4" "Cell line enhanced" "Detected in some" "Daudi: 13.6;HEL: 10.6;HL-60: 9.6;U-266/70: 31.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037002 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 19000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA037002: AB_10672383" "unprognostic (1.59e-2)" "unprognostic (2.08e-2)" "unprognostic (6.43e-2)" "unprognostic (1.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.73e-2)" "unprognostic (4.89e-2)" "unprognostic (1.62e-2)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (4.25e-2)" "unprognostic (7.89e-2)" "unprognostic (2.80e-1)" "unprognostic (2.18e-1)" "unprognostic (2.75e-2)" "unprognostic (6.09e-3)" "unprognostic (1.75e-1)" 8.5 3.6 0.6 35.1 0.6 6.2 2.2 1.5 0.9 2.3 0.2 2.8 2.4 0.8 3.2 0.8 2.3 3.0 0.7 0.5 0.7 3.2 0.3 8.1 82.2 0.8 0.8 0.1 0.5 0.4 1.5 0.8 0.9 5.8 3.3 0.2 2.4 4.7 0.1 0.7 24.2 1.0 0.9 56.1 7.4 3.0 1.0 9.7 12.9 0.2 96.4 7.6 0.7 0.6 0.0 3.0 0.0 0.0 3.4 1.4 0.1 0.1 0.1 0.4 0.6 0.1 4.6 13.6 1.2 0.0 0.0 0.2 0.1 1.5 0.4 0.0 0.0 10.6 2.6 0.0 0.1 9.6 0.0 0.6 0.4 0.0 0.0 1.2 0.1 0.0 0.1 4.0 0.6 0.5 0.0 0.6 0.0 0.4 5.7 0.2 0.6 0.0 0.4 6.1 2.6 0.0 0.3 0.2 0.0 0.1 0.5 2.5 1.3 0.0 0.6 0.0 0.0 31.0 0.0 2.2 0.1 5.3 0.0 10.8 1.7 19.7 0.4 0.5 0.1 310.4 0.1 0.2 10.5 253.0 0.1 0.1 0.9 1.5 0.2 5.2 0.2 11.3 0.6 0.6 1.5 0.9 0.5 0.7 0.8 0.8 0.9 0.9 1.0 0.6 3.5 44.8 27.1 6.8 455.9 0.1 2.2 0.5 0.0 0.2 1.7 0.4 0.5 0.0 10.0 3.7 0.0 2.1 5.8 0.0 0.0 0.2 2.8 13.1 1.0 1.3 0.0 6.1 7.3 0.2 0.6 1.4 6.1 15.2 1.3 0.1 0.0 0.1 1.5 0.0 1.6 0.4 2.0 2.9 25.1 2.0 0.0 13.0 5.4 4.7 2.8 1.8 1.0 1.0 1.3 4.1 1.3 0.4 13.7 4.4 0.2 4.2 2.2 0.1 0.0 0.1 0.8 1.9 5.6 0.8 1.1 0.3 12.9 2.1 1.1 4.3 BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" 294.1 213.9 171.5 100.9 175.5 151.3 210.9 171.8 213.9 139.5 202.5 157.7 133.3 127.4 228.9 214.0 151.0 118.0 123.5 183.0 192.1 160.7 185.5 144.5 111.8 190.8 187.5 130.9 266.4 193.7 123.5 143.3 195.3 154.6 166.5 63.9 179.7 177.7 81.9 187.3 143.8 155.0 183.4 138.5 129.3 117.3 186.9 99.7 161.4 75.5 134.6 177.9 145.8 185.0 505.5 482.4 128.0 650.6 593.8 179.1 295.3 269.9 287.5 291.6 371.6 386.8 361.9 315.9 1068.1 412.2 373.9 506.8 337.3 518.6 221.0 152.8 436.9 198.4 350.4 323.3 276.4 335.1 373.2 233.8 454.2 282.3 330.1 298.4 372.6 172.0 268.0 528.3 332.7 535.3 187.3 402.5 145.8 704.6 431.7 207.5 152.8 693.2 459.3 546.8 173.3 241.8 111.8 520.6 350.0 200.3 196.2 320.2 380.0 248.9 234.7 338.9 495.1 518.0 1120.1 397.3 460.9 402.6 223.7 630.5 484.2 489.1 507.5 535.7 454.7 436.1 504.5 507.4 420.7 463.6 439.1 474.7 624.5 449.8 632.3 666.9 457.1 1110.8 171.5 175.5 171.8 213.9 183.0 192.1 190.8 187.5 195.3 183.4 186.9 185.0 184.9 112.2 114.1 14.7 97.5 141.9 232.2 374.0 172.4 53.0 127.3 165.7 60.3 134.4 222.8 128.8 45.9 467.5 113.5 194.1 37.2 252.4 7.8 99.7 70.1 165.5 103.2 59.3 16.9 210.0 444.8 103.6 78.5 103.9 95.6 68.5 199.6 216.0 356.2 32.0 12.8 155.1 244.1 148.4 125.6 20.6 105.3 166.2 160.1 17.8 137.5 138.2 111.2 11.6 12.9 247.1 187.4 98.9 120.8 191.8 242.8 170.9 172.6 51.8 157.8 42.9 106.5 310.3 231.3 174.0 130.4 538.1 114.6 120.4 187.0 260.4 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BOK "BCL2L9, BOKL, MGC4631" ENSG00000176720 "BCL2 family apoptosis regulator BOK" Q9UMX3 2 241551424-241574131 "Plasma proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 218.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 100.8;Oligodendrocytes: 47.0;Proximal tubular cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Cell line enhanced" "Detected in many" "TIME: 65.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (6.16e-2)" "unprognostic (3.01e-2)" "unprognostic (1.24e-3)" "unprognostic (6.30e-2)" "unprognostic (8.63e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-3)" "unprognostic (1.16e-2)" "unprognostic (8.45e-2)" "unprognostic (2.33e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "prognostic favorable (1.09e-9)" "unprognostic (9.48e-3)" "unprognostic (6.81e-2)" "unprognostic (2.46e-1)" "unprognostic (1.09e-1)" 90.6 7.1 88.4 6.2 138.6 0.4 37.7 110.4 110.3 15.6 51.0 38.0 8.1 34.2 16.3 29.5 18.1 22.7 6.3 77.0 87.8 20.5 97.0 20.1 3.7 146.6 120.6 9.9 16.3 3.8 4.7 5.7 127.1 28.5 5.0 1.2 11.8 25.5 2.6 20.0 9.4 20.4 98.5 6.5 21.5 7.7 115.4 1.1 11.0 3.2 3.4 34.9 18.6 218.8 36.0 8.8 15.7 36.2 26.3 15.6 4.4 28.6 11.3 36.9 37.9 16.2 14.6 0.1 9.7 51.0 9.0 32.9 1.7 28.9 13.8 0.1 0.3 0.1 9.3 42.2 21.8 0.2 1.3 15.9 29.2 15.5 4.4 27.8 44.6 2.4 6.4 0.1 36.7 46.0 0.2 0.2 9.9 40.0 26.8 0.4 25.9 0.2 24.2 0.9 14.0 5.4 13.2 8.5 23.3 18.3 24.4 1.3 65.0 0.1 52.8 0.7 3.2 0.1 0.1 0.1 0.1 0.0 2.1 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.7 1.0 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.6 88.4 138.6 110.4 110.3 77.0 87.8 146.6 120.6 127.1 98.5 115.4 218.8 22.5 6.4 32.1 0.3 0.5 7.1 11.5 8.6 5.2 0.2 19.4 10.5 10.2 32.9 6.3 11.0 0.0 2.0 2.5 5.8 15.6 23.2 0.2 6.6 17.6 15.6 11.4 5.3 0.8 11.1 10.5 10.9 5.6 14.4 0.0 2.6 12.5 100.8 0.7 0.0 1.5 3.7 2.0 4.7 1.2 1.5 6.2 0.7 1.8 4.7 0.0 3.9 6.2 7.5 47.0 27.7 2.8 10.5 0.9 26.3 7.1 41.9 1.5 1.3 0.0 11.7 11.2 0.3 8.2 19.8 12.8 6.2 1.6 3.4 6.1 15.1 BTBD6 BDPL ENSG00000184887 "BTB domain containing 6" Q96KE9 14 105248490-105251093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031355 Approved Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA031355: AB_10611812" "prognostic favorable (1.11e-4)" "unprognostic (2.01e-2)" "unprognostic (2.65e-1)" "unprognostic (1.97e-2)" "unprognostic (2.69e-1)" "unprognostic (2.58e-1)" "unprognostic (2.23e-2)" "unprognostic (4.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-1)" "prognostic favorable (2.25e-4)" "unprognostic (8.48e-3)" "prognostic favorable (6.51e-5)" "unprognostic (6.55e-2)" "unprognostic (3.22e-1)" "unprognostic (6.86e-2)" "unprognostic (9.85e-2)" 69.4 26.3 52.1 20.4 52.6 28.2 56.6 48.3 60.3 32.6 48.1 43.8 28.8 31.4 28.1 50.9 30.8 20.5 52.1 54.2 51.7 34.5 44.2 34.7 22.0 49.7 51.0 36.7 13.2 12.6 39.9 15.6 49.9 43.6 23.1 14.6 42.8 23.5 169.4 48.5 39.5 18.8 48.4 31.4 46.9 79.3 52.1 18.4 30.4 144.6 19.0 38.9 37.7 51.3 50.8 39.8 21.4 56.8 66.8 46.2 0.1 45.6 41.1 69.2 46.9 31.3 45.2 15.9 27.4 67.0 14.5 66.2 41.3 43.9 34.0 41.2 33.5 11.7 58.6 0.0 45.6 35.8 21.7 48.3 59.6 31.9 25.7 26.9 55.9 52.2 0.0 0.3 37.3 71.8 37.8 14.5 9.1 47.6 67.6 40.3 0.1 14.9 26.5 55.0 34.8 14.8 42.9 34.3 35.0 14.7 69.9 45.3 37.9 55.5 1.5 82.1 57.8 10.2 14.7 7.8 57.2 16.4 44.1 0.5 0.6 2.9 2.3 1.0 2.2 1.3 2.4 2.3 0.7 0.7 1.8 1.2 0.3 0.4 0.8 1.5 5.3 0.6 52.1 52.6 48.3 60.3 54.2 51.7 49.7 51.0 49.9 48.4 52.1 51.3 31.5 25.6 24.3 3.9 5.4 11.7 25.7 6.5 6.2 23.1 24.0 23.4 22.0 14.3 15.3 11.0 6.2 2.8 25.3 31.0 21.5 5.7 15.0 25.6 19.5 17.8 20.4 5.2 12.4 0.0 3.8 17.3 10.2 34.9 24.7 22.2 17.9 15.4 7.8 20.2 12.5 31.2 10.2 9.8 10.0 35.2 9.3 10.3 12.4 8.4 3.6 19.1 5.2 5.0 3.7 1.0 11.6 7.5 7.6 16.3 20.5 11.6 15.5 18.8 13.1 15.7 13.0 7.8 8.3 9.6 12.6 2.2 16.4 15.2 21.9 19.5 BTD ENSG00000169814 Biotinidase P43251 3 15601341-15722311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 95.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" NA NA 2800000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA052275: AB_2681782" "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" 25.3 16.7 10.7 8.0 12.7 13.1 16.4 20.2 12.6 13.7 11.0 15.9 46.1 13.2 62.4 9.9 18.3 19.9 10.2 11.5 10.3 37.6 95.9 15.9 9.6 12.0 10.0 25.3 44.1 27.7 5.9 17.0 12.6 19.5 17.0 35.2 16.0 21.1 7.8 9.5 30.7 14.1 10.3 11.3 24.4 18.2 9.9 10.6 26.8 11.4 10.4 14.3 7.5 19.1 9.2 22.0 7.8 7.3 51.7 15.3 39.6 15.4 18.4 16.2 28.3 10.1 21.5 4.1 16.3 31.6 7.1 9.7 5.3 16.7 18.7 7.6 11.7 12.9 28.8 24.8 12.7 8.8 14.7 18.3 16.9 42.9 5.1 39.7 30.5 5.9 8.7 32.3 44.7 11.1 4.5 8.2 8.5 16.9 13.0 5.9 18.4 27.9 16.5 17.7 5.3 11.8 17.9 5.2 24.4 15.1 19.9 11.3 24.3 20.5 13.6 19.1 10.1 8.9 11.4 4.1 21.4 7.7 14.4 74.1 20.7 44.9 22.9 19.6 21.0 14.7 23.3 19.2 21.4 13.1 19.7 15.4 19.8 15.0 15.8 24.9 28.8 16.5 10.7 12.7 20.2 12.6 11.5 10.3 12.0 10.0 12.6 10.3 9.9 19.1 14.9 6.4 11.0 11.8 11.7 5.9 12.4 25.0 6.2 13.5 9.1 7.9 6.0 45.8 16.7 18.4 18.8 25.3 19.7 9.9 5.9 21.1 31.0 9.5 6.0 9.1 7.2 4.0 6.6 28.5 22.4 14.5 9.7 5.7 5.1 8.9 20.3 63.3 14.9 5.0 12.2 8.5 16.2 8.2 5.9 17.9 32.3 9.2 10.6 5.6 8.7 19.2 6.2 27.2 23.9 12.0 17.9 18.0 16.6 6.3 52.1 32.0 19.8 54.1 13.1 8.5 8.6 45.3 7.5 7.7 5.5 23.1 13.6 17.4 8.9 9.5 C11orf86 FLJ22675 ENSG00000173237 "Chromosome 11 open reading frame 86" A6NJI1 11 66975277-66977004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 68.0" "Group enriched" "Detected in some" 20 "Distal enterocytes: 212.2;Paneth cells: 132.8;Proximal enterocytes: 506.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 7.2;SiHa: 24.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA039348 Uncertain NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA039348: AB_10673421" "unprognostic (1.54e-2)" "unprognostic (7.67e-3)" "unprognostic (3.02e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "prognostic unfavorable (8.97e-4)" "unprognostic (4.17e-1)" "prognostic unfavorable (6.97e-5)" "prognostic unfavorable (1.02e-5)" "unprognostic (7.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.69e-2)" "unprognostic (3.58e-3)" 0.1 15.4 0.1 0.6 0.1 0.0 0.1 0.1 0.1 0.0 0.1 10.4 68.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.0 64.2 0.7 0.1 0.0 2.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.9 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 212.2 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 132.8 0.0 0.0 0.0 506.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 8.4 0.2 C14orf180 "C14orf77, NRAC" ENSG00000184601 "Chromosome 14 open reading frame 180" Q8N912 14 104579764-104590515 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.8;breast: 26.7;heart muscle: 109.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.7;Cardiomyocytes: 7.6;Fibroblasts: 2.0;Hepatic stellate cells: 3.3;Horizontal cells: 3.3;Smooth muscle cells: 1.4" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "ASC diff: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.48e-2)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (3.19e-3)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (9.80e-2)" 40.8 3.1 0.0 0.1 0.2 0.0 26.7 0.2 0.2 0.9 13.5 0.9 0.3 1.1 0.0 0.0 1.8 0.2 109.5 1.5 0.0 1.8 4.1 0.4 0.0 0.5 0.8 0.8 0.8 0.0 1.8 0.8 0.5 0.6 0.0 0.1 0.9 0.4 5.7 0.6 1.4 0.0 0.0 0.5 2.2 0.1 0.4 0.0 0.9 0.7 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 1.5 0.0 0.5 0.8 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 C19orf12 "DKFZP762D096, MGC10922, MPAN, NBIA4, SPG43" ENSG00000131943 "Chromosome 19 open reading frame 12" Q9NSK7 19 29698886-29715789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 118.9;tongue: 105.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046930 Approved Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA046930: AB_10962836" "unprognostic (1.76e-1)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.01e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.54e-1)" "unprognostic (9.94e-3)" "unprognostic (7.93e-3)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (3.22e-1)" "unprognostic (1.22e-3)" 118.9 25.3 22.1 14.4 25.8 4.4 40.8 16.6 24.8 13.8 12.6 16.8 19.5 14.3 9.0 13.2 12.8 12.9 30.9 23.9 22.7 20.8 69.3 11.3 21.2 20.5 20.3 14.7 17.1 15.4 14.5 13.2 21.7 14.1 9.3 8.5 18.1 12.4 62.2 14.7 17.6 13.4 16.8 16.0 12.9 7.3 23.1 14.1 10.7 105.5 13.6 15.2 11.7 19.9 19.9 39.4 18.4 23.2 45.0 27.5 28.8 23.1 22.7 22.5 29.2 19.1 8.1 16.1 24.1 29.1 20.4 8.5 15.7 9.5 15.1 42.8 28.3 18.0 13.5 33.2 25.1 14.0 22.8 31.8 20.2 13.7 10.9 18.0 20.1 9.8 14.0 20.3 23.7 13.8 9.9 10.1 11.1 17.3 9.9 19.2 19.1 12.3 17.2 20.1 11.3 23.8 13.9 17.8 37.0 18.8 7.6 15.4 20.9 47.4 37.0 19.5 21.2 28.4 27.1 12.0 28.3 8.4 20.3 1.1 2.3 1.4 16.0 2.5 9.4 4.6 9.1 11.6 2.2 3.6 9.2 11.5 2.8 7.1 2.7 5.0 11.9 8.0 22.1 25.8 16.6 24.8 23.9 22.7 20.5 20.3 21.7 16.8 23.1 19.9 9.6 12.8 13.7 9.4 13.7 12.7 11.1 8.2 14.8 15.8 13.2 9.4 30.1 2.8 7.3 9.2 6.2 29.2 21.7 9.2 15.6 17.1 1.8 8.5 16.0 10.4 3.6 9.5 19.5 23.1 25.5 20.0 8.2 8.8 16.5 16.2 14.6 62.4 15.6 5.0 18.3 7.5 8.2 12.5 9.9 1.8 28.9 8.7 10.6 8.4 20.1 15.8 41.2 12.1 17.4 20.0 11.0 29.3 20.7 12.8 24.0 37.5 6.6 9.6 6.6 24.6 13.3 4.6 5.3 10.1 7.7 21.9 21.6 23.8 8.2 7.8 C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "granulocytes: 182.3;Hofbauer cells: 195.3;Kupffer cells: 797.4;Langerhans cells: 226.7;Macrophages: 413.5;monocytes: 278.6;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "HDLM-2: 141.3;HL-60: 70.4;NB-4: 40.3;THP-1: 55.2;U-937: 117.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" 45.4 23.6 16.3 70.8 16.2 115.0 22.3 17.2 29.0 13.2 19.6 15.8 7.3 11.5 6.3 9.8 22.5 31.2 18.1 16.3 18.4 12.5 41.9 85.7 70.4 20.6 17.3 9.4 9.4 4.8 9.1 15.2 19.7 11.7 17.9 9.5 11.2 6.6 10.1 7.8 21.2 37.6 16.7 134.5 12.5 7.6 23.3 27.7 10.0 7.4 55.9 25.1 10.8 21.4 0.3 0.1 0.5 1.1 0.4 0.6 0.6 0.9 0.1 0.3 0.3 0.2 0.4 0.5 0.5 0.2 0.1 0.2 0.8 0.5 0.6 141.3 0.4 0.4 0.5 0.0 0.4 70.4 11.1 0.0 2.6 0.8 0.9 1.0 2.0 0.7 0.5 0.4 0.5 0.5 0.6 40.3 0.2 0.7 0.8 0.1 0.7 0.1 0.3 0.1 0.5 0.2 0.5 0.6 0.8 0.6 0.3 55.2 0.0 0.8 1.0 0.7 0.6 0.6 0.1 0.6 0.3 117.9 1.2 1114.1 1026.8 1294.8 166.6 1529.2 47.6 231.0 206.5 97.3 1021.6 296.4 318.0 193.6 143.3 536.7 1173.4 302.8 66.7 1189.5 16.3 16.2 17.2 29.0 16.3 18.4 20.6 17.3 19.7 16.7 23.3 21.4 4.4 22.4 43.9 8.1 84.1 7.9 0.7 0.4 0.6 4.0 2.2 5.2 3.8 10.0 4.5 7.3 2.1 1.0 103.4 0.6 0.0 0.2 36.7 0.8 0.9 8.1 1.8 23.5 9.2 0.2 2.0 3.2 0.5 1.0 182.3 0.9 15.7 8.9 195.3 0.0 13.0 0.0 0.0 797.4 226.7 90.7 2.8 413.5 12.4 12.2 278.6 0.2 355.3 6.0 7.7 0.2 0.0 0.7 4.2 0.8 0.9 1.0 0.9 4.2 32.9 2.4 2.9 2.4 2.0 0.2 6.5 1.6 59.8 0.3 0.7 0.3 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QTNF1 "CTRP1, FLJ90694, GIP, ZSIG37" ENSG00000173918 "C1q and TNF related 1" Q9BXJ1 17 79022814-79049788 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 214.2;heart muscle: 319.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 120.0;Sertoli cells: 105.2;Smooth muscle cells: 105.8;Syncytiotrophoblasts: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 313.5;BJ hTERT+: 72.9;HHSteC: 112.3;HSkMC: 61.3;U-87 MG: 66.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025429, HPA051101" Uncertain Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 314000000 40000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB025429: , HPA051101: AB_2681343" "unprognostic (2.58e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (1.20e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" "unprognostic (7.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-2)" "unprognostic (7.48e-2)" "unprognostic (9.81e-3)" "unprognostic (5.83e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (1.95e-2)" 214.2 75.3 9.5 14.8 15.2 0.5 156.0 16.1 13.3 50.2 45.3 38.3 4.6 45.1 6.5 18.9 63.5 24.3 319.1 9.1 18.2 25.3 45.7 44.4 14.0 18.3 25.4 70.5 14.9 13.5 17.5 42.2 18.0 57.1 6.3 0.9 34.9 44.0 27.0 38.6 29.3 13.3 14.1 35.7 25.0 5.4 21.9 5.1 115.0 21.3 6.6 34.7 42.3 13.2 0.1 32.3 0.3 0.1 313.5 27.1 0.2 13.6 72.9 7.0 11.9 2.7 14.0 0.1 1.5 5.1 18.1 0.7 1.0 0.5 5.0 0.1 3.5 0.2 11.7 1.5 112.3 0.1 0.2 61.3 0.2 14.5 0.8 9.3 8.8 1.6 0.1 0.3 1.6 0.1 0.3 0.2 3.0 3.7 27.9 0.1 22.3 0.4 0.0 0.4 1.3 5.3 9.2 1.8 32.7 1.2 0.0 0.0 1.4 32.6 0.8 4.0 4.8 0.3 0.1 0.1 66.2 0.2 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.5 15.2 16.1 13.3 9.1 18.2 18.3 25.4 18.0 14.1 21.9 13.2 36.1 0.0 0.6 4.9 0.4 6.5 0.7 12.3 0.6 0.1 9.2 1.8 10.8 5.7 0.5 1.8 0.0 21.5 0.4 3.2 0.0 19.5 0.1 0.6 17.9 38.3 4.8 2.7 0.2 5.9 1.5 23.6 2.6 0.6 0.0 25.3 120.0 1.9 2.6 0.0 0.9 6.3 2.0 7.5 11.3 0.7 10.5 1.1 3.6 5.6 10.9 0.5 0.0 0.5 0.3 3.7 3.1 3.4 0.1 1.8 0.9 0.2 0.3 0.5 105.2 12.7 105.8 0.0 0.7 0.4 4.5 47.3 0.8 18.1 5.2 0.6 C20orf27 FLJ20550 ENSG00000101220 "Chromosome 20 open reading frame 27" Q9GZN8 20 3753508-3767781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 178.7;Hofbauer cells: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 144.6;intermediate monocyte: 249.1;myeloid DC: 199.4;non-classical monocyte: 235.3" "Group enriched" "Detected in all" 5 "dendritic cells: 199.4;monocytes: 249.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047483 Approved Approved Nucleoplasm,Cytosol NA NA 140000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA047483: AB_2680064" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.21e-3)" "unprognostic (2.99e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (1.69e-5)" "unprognostic (8.36e-2)" "unprognostic (2.07e-1)" "unprognostic (4.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (1.80e-1)" "unprognostic (2.16e-1)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" 55.8 24.0 48.8 20.4 125.4 103.6 45.2 44.7 70.9 39.5 33.7 117.3 17.0 42.5 8.7 29.6 51.8 25.5 27.9 45.6 63.3 25.7 24.7 20.8 24.5 52.9 59.3 66.3 23.6 9.4 23.3 8.9 67.5 24.2 7.8 4.9 15.7 10.9 22.4 26.9 33.9 14.1 43.8 45.5 86.8 22.7 59.5 11.0 23.4 11.5 9.8 73.9 26.3 40.7 172.9 177.7 24.4 106.1 49.5 28.1 42.7 45.5 25.1 70.4 50.3 120.5 61.6 111.1 41.4 48.2 94.7 140.9 65.7 101.9 24.9 26.1 138.3 63.2 35.9 212.6 36.2 88.2 24.7 41.0 41.8 93.3 46.1 24.2 48.2 72.9 114.6 59.8 37.3 240.2 107.6 186.3 114.9 107.0 248.4 86.6 67.9 123.7 43.9 62.0 121.8 56.6 41.2 155.3 85.1 10.4 36.9 96.8 35.9 104.8 73.8 171.6 129.6 50.5 93.2 80.7 31.5 161.2 53.9 1.3 144.6 2.3 28.7 249.1 42.1 38.7 33.6 38.6 199.4 36.2 37.6 37.5 5.4 32.5 235.3 38.7 34.2 87.4 48.8 125.4 44.7 70.9 45.6 63.3 52.9 59.3 67.5 43.8 59.5 40.7 54.0 0.0 3.3 3.3 26.5 24.2 23.0 26.8 35.3 9.7 28.2 45.7 3.7 8.6 7.4 11.0 2.1 17.5 15.8 10.2 29.4 32.6 21.8 13.8 178.7 28.7 15.7 99.1 6.0 30.0 49.2 27.1 14.3 7.5 22.9 45.0 19.6 17.9 142.9 1.7 9.5 15.9 16.2 119.0 53.1 15.3 32.6 92.2 37.4 5.6 97.4 24.6 15.5 3.5 2.1 34.7 14.6 24.8 20.2 46.6 19.3 32.4 2.7 13.6 65.7 17.1 98.8 27.3 39.1 34.8 32.8 7.3 24.1 69.7 33.0 22.7 C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 126.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 51.6;Cone photoreceptor cells: 83.4;Granulosa cells: 100.0;Theca cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 79.1;SK-BR-3: 44.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA030922: AB_2673660, HPA030924: AB_10669873" "unprognostic (3.02e-3)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (9.63e-2)" "unprognostic (3.15e-3)" "unprognostic (2.93e-2)" "unprognostic (2.39e-2)" "unprognostic (3.44e-2)" "unprognostic (3.00e-2)" "unprognostic (4.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" 39.9 126.3 18.6 8.3 18.0 1.3 23.3 18.4 19.8 12.0 16.9 12.9 4.9 8.3 8.4 10.7 9.4 8.3 7.5 16.4 18.6 10.1 8.6 7.9 9.7 21.8 20.9 18.9 11.3 29.2 7.2 5.2 20.2 17.3 5.8 24.6 10.8 11.5 2.8 15.6 9.0 7.8 20.5 41.4 11.7 3.3 23.4 6.7 8.5 4.1 7.9 12.8 11.4 26.1 13.4 5.5 3.9 8.9 79.1 21.7 15.1 9.3 14.4 5.7 5.2 8.7 15.0 0.2 5.0 18.0 14.0 1.5 13.9 9.7 7.2 0.9 6.2 2.3 7.1 7.1 10.6 1.0 0.0 14.0 8.9 30.3 11.7 12.5 27.1 0.7 8.4 0.1 15.3 1.2 1.9 2.7 21.4 5.7 18.7 1.4 5.7 8.0 8.5 27.8 6.3 2.8 10.1 44.6 8.1 7.6 11.7 5.9 9.3 13.5 1.9 4.5 7.6 5.0 7.9 1.1 39.2 7.7 2.8 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.1 0.5 0.3 0.1 0.3 0.1 0.0 0.3 0.1 18.6 18.0 18.4 19.8 16.4 18.6 21.8 20.9 20.2 20.5 23.4 26.1 24.8 3.2 15.5 20.5 4.4 4.1 9.1 7.6 15.9 51.6 8.2 7.0 3.1 8.6 8.3 3.7 83.4 12.8 4.4 3.4 0.0 5.6 0.3 6.0 6.7 19.3 4.9 5.9 20.3 8.5 4.8 11.9 17.9 8.3 0.0 100.0 46.1 5.2 3.6 1.7 14.4 6.9 6.1 7.0 10.5 0.2 3.7 5.6 1.8 24.4 2.5 3.6 3.1 11.6 18.8 8.1 5.0 2.2 8.1 15.9 3.0 2.5 7.7 36.9 13.1 7.4 17.9 0.1 3.0 14.3 2.6 9.3 2.8 82.4 6.9 16.6 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 125.5;lymphoid tissue: 84.8" "Group enriched" "Detected in many" 4 "Hofbauer cells: 130.9;Kupffer cells: 228.3;Langerhans cells: 122.4;Macrophages: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 394.0" "Group enriched" "Detected in many" 42 "granulocytes: 394.0;monocytes: 115.9" "Cell line enhanced" "Detected in some" "A549: 3.9;CAPAN-2: 4.1;HMC-1: 4.7;U-87 MG: 6.2;U-937: 6.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" 72.7 18.2 3.3 84.8 3.1 125.5 8.5 2.4 9.0 11.8 21.6 9.8 2.5 7.5 1.4 8.3 23.9 38.8 11.7 3.9 8.2 9.7 18.0 43.1 11.5 8.9 6.9 5.0 8.9 4.8 51.8 31.8 8.4 5.3 4.2 4.4 5.1 2.5 1.9 2.3 5.8 28.1 5.7 38.2 7.2 2.6 10.5 7.1 3.6 5.8 4.3 37.1 4.6 11.6 1.0 3.9 0.1 0.1 0.7 0.2 0.6 0.7 0.5 0.2 0.1 0.2 4.1 0.3 0.7 0.9 0.4 1.4 0.2 0.5 0.2 0.7 0.5 0.1 3.8 0.6 0.4 1.5 4.7 0.3 2.2 0.4 0.3 0.6 0.0 0.2 0.2 1.7 0.1 1.1 0.2 2.5 1.2 0.2 0.3 0.2 0.1 0.3 1.3 0.9 0.0 0.0 0.3 0.3 0.6 0.5 0.2 2.2 0.0 0.1 2.1 0.3 0.1 0.2 0.3 0.3 6.2 6.5 0.2 41.6 53.8 38.8 0.4 80.4 0.3 0.4 0.3 0.2 6.1 0.6 0.3 0.3 394.0 0.5 115.9 1.1 0.3 19.3 3.3 3.1 2.4 9.0 3.9 8.2 8.9 6.9 8.4 5.7 10.5 11.6 4.4 3.2 20.8 0.0 5.1 5.1 1.0 3.4 2.8 1.0 2.1 4.4 2.9 1.5 15.3 1.8 2.1 0.8 1.5 1.6 3.9 0.0 1.3 17.3 1.8 6.3 0.0 0.4 1.5 0.0 1.5 5.3 1.1 4.6 25.2 0.1 2.9 8.3 130.9 0.0 0.6 0.8 4.1 228.3 122.4 1.3 0.6 446.7 5.4 5.6 56.3 0.2 0.0 1.0 0.3 0.1 0.1 0.0 4.9 0.5 0.7 1.3 40.7 4.3 13.1 4.1 2.8 0.5 0.9 1.4 3.0 1.5 3.3 0.0 1.3 0.5 C9orf24 "bA573M23.4, CBE1, MGC32921, MGC33614, NYD-SP22, SMRP1" ENSG00000164972 "Chromosome 9 open reading frame 24" Q8NCR6 9 34379019-34397810 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 39.2;choroid plexus: 105.6;fallopian tube: 108.7;testis: 90.6" "Cell type enhanced" "Detected in many" "Early spermatids: 744.6;Endometrial ciliated cells: 841.0;Late spermatids: 3115.3;Respiratory ciliated cells: 1312.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053008 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Cytosol "HPA053008: AB_2682015" "unprognostic (3.62e-3)" "unprognostic (9.06e-3)" "unprognostic (1.00e-1)" "prognostic favorable (3.23e-5)" "unprognostic (7.66e-2)" "unprognostic (1.21e-2)" "unprognostic (2.40e-1)" "unprognostic (1.25e-1)" "unprognostic (2.72e-1)" "unprognostic (1.58e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.33e-1)" "unprognostic (6.39e-3)" "unprognostic (1.50e-1)" "unprognostic (7.43e-3)" "unprognostic (4.72e-2)" "unprognostic (1.90e-2)" 1.2 0.6 20.6 0.3 26.6 0.0 0.7 19.5 29.8 7.8 105.6 3.2 1.9 0.7 0.0 0.4 108.7 0.3 17.5 20.8 22.8 3.4 0.3 18.4 0.2 35.9 39.2 0.4 0.9 0.1 10.6 0.2 29.8 1.6 0.7 1.2 1.9 0.4 1.4 0.6 5.4 0.5 33.0 0.2 1.4 90.6 22.3 0.3 0.6 1.7 0.3 0.9 0.4 25.5 0.2 0.0 0.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.3 0.4 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.3 0.0 0.4 1.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.2 0.6 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.8 0.3 0.0 0.2 0.0 0.0 0.4 0.1 20.6 26.6 19.5 29.8 20.8 22.8 35.9 39.2 29.8 33.0 22.3 25.5 0.4 6.4 15.1 11.4 0.3 2.2 3.3 67.3 2.2 1.4 1.6 1.8 37.0 1.5 116.4 7.3 0.0 0.6 0.1 11.3 72.4 1.1 744.6 841.0 6.1 2.1 12.1 0.0 11.3 1.5 0.3 3.5 0.5 9.8 8.8 0.2 1.4 4.1 0.4 0.0 12.6 13.4 81.4 1.0 1.0 3115.3 10.5 2.7 0.0 1.0 0.0 2.2 1.0 4.0 5.4 0.2 7.3 7.2 0.5 4.5 142.5 13.7 1312.6 0.9 32.9 0.5 25.5 21.0 6.9 0.4 1.0 0.5 1.6 0.0 20.5 2.4 CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 258.2;Glandular and luminal cells: 54.3;Oligodendrocyte precursor cells: 163.3" "Cancer enriched" "Detected in all" 5 "melanoma: 38.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "SK-MEL-30: 154.3;U-266/70: 216.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073649 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA073649: AB_2732233" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "prognostic favorable (4.71e-6)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (4.80e-2)" "unprognostic (7.81e-2)" 17.1 3.3 63.9 2.1 67.9 2.6 13.8 36.8 54.8 6.9 17.1 5.2 7.5 9.4 3.2 6.9 10.9 5.2 4.6 44.9 53.5 13.1 9.9 21.5 2.8 39.6 59.0 3.7 3.0 21.9 4.0 10.4 40.8 3.7 5.1 8.0 22.3 4.5 1.5 17.2 6.7 6.6 31.2 3.7 14.5 3.5 70.2 4.9 15.0 1.8 2.3 5.4 7.8 33.3 13.1 14.4 11.8 0.9 7.1 0.3 20.4 3.1 17.3 4.2 2.5 9.5 23.0 0.7 13.3 14.9 42.3 11.4 9.0 2.3 3.2 0.3 19.4 1.0 38.7 37.1 6.2 2.5 1.0 4.2 2.1 5.3 6.1 26.8 47.1 2.3 0.5 16.2 11.7 30.2 0.1 8.8 7.5 64.5 46.6 3.1 42.2 50.6 21.2 31.5 11.2 8.2 26.1 32.5 154.3 8.3 52.4 7.2 79.3 47.9 0.5 1.6 3.8 216.0 88.9 27.4 0.2 19.2 16.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 63.9 67.9 36.8 54.8 44.9 53.5 39.6 59.0 40.8 31.2 70.2 33.3 2.9 22.4 27.4 258.2 3.8 5.1 2.0 1.4 5.2 4.1 9.2 6.7 1.4 7.2 2.3 3.7 29.2 0.9 1.3 8.5 1.9 1.1 2.0 11.6 4.4 6.0 3.5 1.3 19.2 2.3 1.1 4.1 10.2 54.3 0.0 14.8 25.0 9.3 16.6 0.0 22.2 4.6 0.0 3.5 3.1 3.5 0.0 4.7 28.4 41.2 0.0 1.4 0.0 163.3 1.4 2.4 5.2 6.0 3.6 0.6 6.7 14.3 1.8 18.7 0.0 5.0 2.1 0.2 3.2 1.6 6.7 0.3 1.4 0.5 2.1 2.2 CALB2 CAL2 ENSG00000172137 "Calbindin 2" P22676 16 71358713-71390436 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 100.5;brain: 131.9;breast: 53.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 97.8;granulocytes: 251.5;Granulosa cells: 44.1;Theca cells: 70.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "hypothalamus: 76.3;medulla oblongata: 89.5;midbrain: 42.2;pons: 86.7;thalamus: 131.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 21.5;HEL: 63.9;HMC-1: 133.0;U-2 OS: 38.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 449.0" "CAB000106, HPA007305, HPA007306" Enhanced Supported Enhanced Cytosol NA NA 9600 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "CAB000106: AB_2068519, HPA007305: AB_1078386, HPA007306: AB_1078385" "unprognostic (1.10e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.78e-5)" "unprognostic (1.75e-3)" "unprognostic (5.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.55e-3)" "unprognostic (4.28e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-3)" "unprognostic (1.35e-2)" "unprognostic (5.54e-4)" "unprognostic (1.97e-3)" "unprognostic (6.30e-2)" "unprognostic (4.72e-2)" "unprognostic (1.04e-2)" 100.5 36.6 19.9 4.1 15.4 0.0 53.5 16.5 20.0 3.5 4.1 13.8 0.7 0.7 0.5 7.7 7.7 1.1 7.7 12.8 76.3 0.3 0.2 3.6 0.1 89.5 42.2 11.4 0.7 0.0 14.3 0.0 86.7 0.9 4.7 23.6 11.1 0.4 0.5 4.9 6.2 1.7 16.0 0.1 1.0 13.0 131.9 0.1 0.2 0.2 0.9 2.0 2.7 8.4 19.1 2.0 17.0 0.0 0.6 0.1 3.3 0.6 0.3 0.5 0.1 0.1 21.5 0.0 0.3 0.2 2.7 3.7 0.0 0.0 0.2 0.1 0.1 63.9 0.0 0.6 0.1 0.0 133.0 0.0 0.0 1.3 0.2 0.3 0.0 1.6 0.0 0.5 0.1 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.1 0.2 0.1 0.6 0.0 0.1 0.0 3.1 38.0 0.3 3.8 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 15.4 16.5 20.0 12.8 76.3 89.5 42.2 86.7 16.0 131.9 8.4 0.5 9.6 7.2 0.3 0.0 0.3 0.1 0.2 0.0 12.5 10.3 2.3 0.4 1.5 0.0 0.0 6.2 0.0 0.0 0.0 0.0 1.8 2.6 0.3 10.8 0.7 0.0 0.0 0.4 97.8 0.1 29.6 0.0 0.1 251.5 44.1 0.0 0.1 0.1 30.3 17.4 0.0 0.0 0.0 0.4 2.4 6.2 1.2 5.4 1.0 0.0 2.5 0.0 0.0 0.6 16.5 0.0 0.0 0.1 0.1 0.0 0.0 1.5 10.3 0.0 0.2 1.9 1.8 5.0 0.0 0.0 0.1 3.5 70.2 0.0 0.2 CCDC107 MGC31967 ENSG00000159884 "Coiled-coil domain containing 107" Q8WV48 9 35658290-35661511 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016857, HPA050442" Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA016857: AB_10669751, HPA050442: AB_2681128" "unprognostic (3.70e-3)" "unprognostic (7.07e-3)" "unprognostic (3.60e-2)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.09e-2)" "unprognostic (4.13e-1)" "unprognostic (1.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.33e-2)" "unprognostic (1.89e-1)" "unprognostic (5.15e-1)" "unprognostic (1.96e-1)" "unprognostic (5.75e-2)" 91.6 61.0 35.1 19.1 34.6 7.8 75.3 37.4 40.6 48.5 36.0 117.8 19.2 74.2 31.1 25.1 60.6 15.3 90.3 34.5 35.3 37.7 50.3 43.6 15.4 35.5 35.7 32.3 62.7 12.8 33.0 13.9 36.0 55.9 16.8 13.9 26.6 29.2 64.4 32.5 47.1 28.2 34.7 41.2 74.4 17.1 37.3 26.0 31.4 22.4 14.4 76.6 39.1 35.0 17.9 15.7 12.8 16.3 63.3 40.3 7.4 29.5 26.4 18.5 17.2 7.2 5.2 11.5 12.8 38.9 47.6 5.9 9.6 14.2 13.6 34.4 15.3 5.5 25.1 18.3 15.0 8.5 20.1 24.1 16.6 19.8 15.3 34.4 13.1 19.2 7.2 21.7 23.4 11.6 9.5 12.6 9.5 12.6 48.2 13.7 2.9 9.3 62.8 9.6 8.4 14.0 15.2 21.1 15.4 9.5 11.1 10.4 16.7 29.5 16.3 21.6 27.3 9.6 15.4 23.1 54.6 13.5 26.2 33.3 39.3 20.1 128.7 43.2 168.8 79.5 111.6 113.8 45.0 79.5 53.2 74.2 7.8 69.3 25.9 123.8 140.8 75.1 35.1 34.6 37.4 40.6 34.5 35.3 35.5 35.7 36.0 34.7 37.3 35.0 68.7 67.3 25.0 11.1 104.8 70.2 38.0 76.9 8.6 31.9 39.2 65.3 0.7 60.1 48.4 82.8 8.4 15.0 175.2 143.9 17.6 74.1 7.6 33.5 34.1 36.1 88.1 15.8 8.6 140.2 66.2 60.0 121.8 30.5 34.3 24.4 53.9 77.3 90.9 32.0 10.2 100.5 69.2 46.9 185.9 28.3 59.4 82.0 113.8 13.1 43.5 57.2 133.9 7.5 10.8 86.7 108.6 102.3 53.3 45.3 146.7 66.9 48.2 34.1 118.3 33.7 135.3 37.9 63.1 17.8 66.9 13.8 132.7 44.9 51.7 29.5 CCDC178 "C18orf34, FLJ44050" ENSG00000166960 "Coiled-coil domain containing 178" Q5BJE1 18 32937402-33441101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.9;testis: 15.2" "Cell type enhanced" "Detected in some" "Adipocytes: 29.2;Early spermatids: 89.0;Late spermatids: 76.8;Spermatocytes: 49.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "HUVEC TERT2: 5.1;U-87 MG: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (9.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (2.58e-3)" "unprognostic (2.92e-1)" "unprognostic (5.95e-4)" "unprognostic (4.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.94e-4)" "unprognostic (2.86e-1)" "unprognostic (1.42e-3)" "unprognostic (9.03e-3)" 10.9 0.3 0.2 0.2 0.3 0.0 7.8 0.0 0.4 2.7 0.1 0.8 0.5 1.3 2.2 0.6 1.5 2.5 0.5 0.2 0.3 2.8 0.1 0.7 0.2 0.4 0.6 4.0 0.1 0.0 0.6 0.0 0.2 3.5 0.5 0.1 0.5 2.0 0.3 0.7 0.6 1.5 0.4 7.6 0.6 15.2 0.1 0.1 0.8 0.0 0.6 2.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.3 0.4 0.6 0.2 0.4 0.1 0.2 29.2 0.0 0.0 0.3 0.0 0.4 0.4 0.0 2.2 0.0 0.1 0.4 0.3 0.0 0.0 1.8 0.0 0.0 0.1 0.0 9.8 0.0 89.0 0.6 0.3 12.8 0.0 0.0 7.9 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 76.8 1.8 0.2 0.0 2.8 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.7 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 49.4 16.3 0.1 0.3 0.0 0.0 6.1 0.0 0.0 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 141.6" "Cell type enriched" "Detected in some" 5 "Theca cells: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.2;HUVEC TERT2: 9.0;NTERA-2: 4.6;RH-30: 3.2;SCLC-21H: 7.7;TIME: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" 15.9 5.4 7.2 1.6 7.3 0.0 15.0 9.5 6.8 8.7 4.2 4.6 1.3 8.9 0.6 3.7 7.7 2.5 23.2 6.1 5.8 13.3 2.2 11.8 1.5 6.8 6.4 3.6 2.6 1.4 4.1 7.8 7.0 5.8 1.1 0.4 3.4 1.8 4.8 3.9 5.4 3.3 6.1 141.6 4.2 1.6 7.3 0.8 10.2 4.8 0.9 6.4 6.3 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 9.0 0.9 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.1 0.0 0.6 3.2 0.1 0.0 0.0 7.7 0.9 0.2 0.0 0.0 1.1 2.5 0.0 4.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 7.3 9.5 6.8 6.1 5.8 6.8 6.4 7.0 6.1 7.3 5.2 45.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.5 0.6 4.6 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.2 32.1 0.0 0.0 2.9 0.2 0.0 1.0 0.0 0.2 0.0 4.3 24.3 0.0 0.0 3.3 2.4 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.8 0.3 0.6 0.1 0.3 0.0 0.1 248.7 0.0 0.1 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.0;Erythroid cells: 26.5;Hofbauer cells: 42.7;Kupffer cells: 22.1;Langerhans cells: 36.5;Macrophages: 56.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 21.0;OE19: 8.4;PC-3: 15.3;RT4: 8.3;TIME: 15.4;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" 11.7 1.6 2.1 11.4 2.1 9.0 8.4 2.2 3.7 2.3 2.2 11.5 11.7 1.2 0.6 0.9 1.1 5.5 2.7 2.1 2.2 2.2 4.4 12.4 4.9 2.8 2.3 0.5 1.5 0.8 0.8 5.1 3.1 0.8 10.4 0.2 0.9 0.8 1.1 0.7 12.1 2.5 2.6 8.5 5.5 0.3 2.9 7.7 1.3 1.1 3.8 6.0 1.1 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.2 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.7 4.6 0.0 21.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 5.0 0.2 0.0 7.2 4.2 2.8 0.1 5.0 0.0 1.6 2.6 0.0 8.4 15.3 0.4 0.3 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 15.4 0.6 0.3 0.7 0.3 0.0 8.6 0.2 7.5 6.5 0.0 8.7 15.4 4.3 2.8 22.1 3.4 1.7 1.6 4.7 9.9 3.9 1.0 2.5 2.6 6.7 10.1 3.0 4.7 5.0 2.1 2.1 2.2 3.7 2.1 2.2 2.8 2.3 3.1 2.6 2.9 3.3 35.0 0.0 4.7 0.0 4.4 2.0 0.2 0.2 0.0 0.0 0.4 0.4 1.1 1.5 1.2 0.0 0.0 0.3 4.5 19.5 0.0 0.6 0.1 0.1 0.2 12.1 0.0 26.5 0.0 8.8 1.2 1.4 4.6 0.1 9.5 0.1 6.4 0.4 42.7 0.0 0.0 16.6 0.0 22.1 36.5 0.0 0.0 56.2 1.8 1.9 6.7 0.0 0.0 0.0 0.0 9.8 12.4 0.0 4.2 0.2 17.2 0.2 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 1.1 2.5 6.4 0.4 9.2 1.1 CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.2;placenta: 22.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 15.6;Langerhans cells: 14.7;Macrophages: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 4 "dendritic cells: 1.2;monocytes: 1.4" "Cell line enriched" "Detected in single" 14 "THP-1: 3.3" "CAB032436, CAB033831" Supported "Intracellular and membrane" NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" 34.2 3.9 0.3 8.6 0.6 0.4 4.4 1.3 3.0 4.0 5.7 10.5 14.3 1.4 1.0 4.8 2.5 8.6 4.5 0.3 0.7 2.1 3.3 4.9 18.1 1.0 0.6 1.0 1.0 0.8 0.7 22.8 0.8 0.8 13.9 0.1 2.1 1.9 0.9 1.4 19.3 10.6 0.9 2.4 4.1 2.1 0.6 5.4 1.4 1.5 2.3 20.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.4 0.3 0.6 1.3 3.0 0.3 0.7 1.0 0.6 0.8 0.9 0.6 0.8 0.3 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 15.6 14.7 0.3 0.0 12.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.1 CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lung: 8.4;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 5 "granulocytes: 15.2;Hofbauer cells: 32.1;Kupffer cells: 26.3;Langerhans cells: 15.3;Macrophages: 36.1;monocytes: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.3;non-classical monocyte: 242.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.1;HMC-1: 33.1;THP-1: 6.5;U-937: 16.2" "Low region specificity" "Detected in some" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: AB_1846293, HPA060349: " "unprognostic (1.55e-2)" "unprognostic (2.60e-1)" "unprognostic (9.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.68e-2)" "unprognostic (7.51e-2)" "unprognostic (6.51e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-3)" "unprognostic (6.27e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" 4.0 1.3 0.7 6.8 1.1 9.7 0.8 0.8 5.5 0.6 1.1 1.3 1.1 0.6 0.1 0.6 0.7 2.0 0.9 0.7 1.4 0.7 1.5 8.4 2.1 1.7 1.8 0.3 0.6 0.4 0.4 2.9 2.1 0.5 1.3 0.0 0.7 0.5 0.3 0.4 1.2 3.1 1.4 7.3 0.7 0.3 2.7 1.0 1.0 0.2 1.1 3.8 0.4 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 3.3 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.6 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 16.2 0.0 51.8 142.1 7.0 0.7 228.3 0.4 2.7 0.3 0.3 158.8 2.4 0.2 0.2 5.2 43.9 242.7 10.5 0.2 64.6 0.7 1.1 0.8 5.5 0.7 1.4 1.7 1.8 2.1 1.4 2.7 2.2 0.1 0.0 1.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.7 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 15.2 0.0 0.0 0.2 32.1 0.0 0.0 0.0 0.0 26.3 15.3 0.1 0.0 36.1 1.8 1.0 19.6 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 1.3 0.0 0.0 0.0 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD53 "MOX44, TSPAN25" ENSG00000143119 "CD53 molecule" P19397 1 110871188-110899922 "CD markers, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 448.3" "Cell type enhanced" "Detected in many" "B-cells: 310.0;dendritic cells: 375.0;Hofbauer cells: 365.7;Kupffer cells: 324.3;Macrophages: 294.8;NK-cells: 383.1;T-cells: 297.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 473.5;HDLM-2: 214.8;HMC-1: 298.4;Karpas-707: 188.1;U-266/70: 251.2;U-698: 149.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047216 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "HPA047216: AB_2679986" "unprognostic (2.93e-2)" "unprognostic (1.25e-2)" "unprognostic (7.45e-3)" "unprognostic (1.02e-3)" "unprognostic (8.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.96e-1)" "unprognostic (6.07e-2)" "unprognostic (2.83e-2)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.58e-2)" "unprognostic (4.95e-2)" "unprognostic (1.33e-1)" "unprognostic (7.72e-2)" 63.4 30.8 10.1 284.4 11.1 126.6 27.0 12.6 16.3 20.8 12.3 41.5 37.9 17.3 10.5 20.0 22.8 58.5 12.2 9.7 13.4 15.1 46.8 114.9 397.9 18.9 16.0 9.2 11.9 6.6 6.2 58.5 18.9 12.8 54.8 2.0 19.3 12.8 4.5 6.7 103.4 55.8 18.3 269.4 44.3 5.7 17.5 144.9 11.3 10.6 448.3 85.1 9.0 31.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 473.5 0.2 0.0 0.2 0.5 0.0 0.0 0.0 214.8 0.0 26.4 0.1 0.0 0.0 60.4 298.4 0.0 0.0 0.0 0.0 0.0 0.0 139.2 11.2 188.1 0.0 0.0 103.1 71.1 0.4 0.0 0.0 98.0 0.7 104.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 1.5 0.0 88.4 17.2 0.2 0.4 0.1 0.5 251.2 123.2 149.2 1.5 68.7 3.4 1483.0 779.5 479.0 732.4 808.6 658.1 794.0 527.8 649.2 631.9 745.1 377.9 552.5 1144.2 526.6 882.9 517.5 740.3 1621.0 10.1 11.1 12.6 16.3 9.7 13.4 18.9 16.0 18.9 18.3 17.5 31.9 4.2 16.0 24.4 0.7 310.0 7.0 0.6 0.0 0.6 0.0 2.3 5.1 1.0 5.7 8.6 1.8 0.0 2.1 375.0 0.2 0.0 0.5 0.4 0.4 0.5 13.0 0.0 42.9 5.8 0.2 5.4 6.7 7.1 0.6 162.2 0.0 16.4 6.7 365.7 0.0 1.4 0.3 0.0 324.3 161.5 1.9 2.1 294.8 39.2 69.3 156.3 0.1 383.1 1.0 0.6 0.3 0.1 0.4 134.0 0.3 0.0 1.6 4.4 0.6 6.6 1.9 1.8 0.1 0.6 1.1 5.5 4.1 297.0 0.0 0.2 0.3 CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.6;lymphoid tissue: 43.1" "Cell type enhanced" "Detected in many" "dendritic cells: 25.7;NK-cells: 49.4;Plasma cells: 18.5;T-cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 33 "gdT-cell: 27.7;MAIT T-cell: 24.7;memory CD4 T-cell: 51.4;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.4;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 51 "T-cells: 51.4" "Group enriched" "Detected in some" 12 "JURKAT: 10.2;MOLT-4: 39.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" NA NA 5270000 160000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" 1.4 0.9 1.5 21.9 0.9 11.3 1.2 0.5 1.1 1.3 0.7 3.2 4.0 0.9 0.7 1.8 1.4 3.9 0.5 0.6 1.7 1.0 1.4 6.6 43.1 1.5 2.0 0.9 0.6 0.2 0.4 0.3 1.7 1.1 3.1 0.2 3.2 0.4 0.8 1.3 13.6 0.7 0.9 18.0 6.6 0.7 2.5 39.6 1.4 0.3 29.0 4.8 1.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.2 0.0 0.0 0.0 39.2 0.1 0.2 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.4 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.7 0.0 24.7 1.0 51.4 48.4 0.3 0.9 34.4 25.2 0.7 0.2 0.0 0.0 25.5 13.8 1.5 0.9 0.5 1.1 0.6 1.7 1.5 2.0 1.7 0.9 2.5 0.9 3.2 0.0 2.5 0.3 10.8 2.0 0.2 0.1 0.0 1.4 0.9 0.8 2.6 1.5 0.1 0.0 0.0 0.2 25.7 0.2 0.0 0.2 0.9 0.4 0.3 1.2 0.0 0.0 0.8 0.6 0.2 1.5 8.2 0.3 0.0 0.1 2.5 0.8 2.0 1.7 0.9 0.0 0.0 1.9 4.4 0.4 0.3 3.4 3.6 1.0 2.4 0.0 49.4 0.0 0.2 0.7 0.2 0.0 18.5 0.0 0.1 0.2 0.1 0.2 0.0 1.0 0.9 0.4 0.9 1.0 1.4 0.3 107.3 0.7 0.5 0.4 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDH20 "Cdh7, CDH7L3" ENSG00000101542 "Cadherin 20" Q9HBT6 18 61333430-61555779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 33.7;retina: 11.0;tongue: 24.1" "Group enriched" "Detected in some" 6 "Astrocytes: 1264.4;Oligodendrocyte precursor cells: 742.4;Oligodendrocytes: 1030.7" "Cancer enriched" "Detected in single" 15 "glioma: 6.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 2.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.3" "Cell line enhanced" "Detected in some" "AF22: 1.8;ASC diff: 5.7;HHSteC: 2.6;SH-SY5Y: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015490 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA015490: AB_1845900" "unprognostic (2.15e-1)" "unprognostic (1.66e-2)" "unprognostic (1.42e-2)" "unprognostic (3.68e-3)" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.87e-2)" "unprognostic (1.40e-2)" "unprognostic (1.52e-1)" "unprognostic (3.69e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (3.82e-2)" "unprognostic (1.27e-1)" "unprognostic (3.01e-2)" "unprognostic (1.93e-1)" 4.7 0.1 22.1 0.0 29.9 0.0 0.9 24.8 19.9 0.2 2.3 0.0 0.0 0.1 0.6 0.8 0.2 0.0 0.1 20.0 19.8 0.1 0.0 0.0 0.0 27.5 28.7 0.0 0.1 0.0 1.6 0.0 29.1 0.2 0.0 11.0 0.4 0.0 4.7 0.5 0.2 0.0 21.5 0.1 0.1 0.4 23.1 0.0 0.3 24.1 0.0 0.3 0.0 33.7 0.0 0.0 1.8 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 22.1 29.9 24.8 19.9 20.0 19.8 27.5 28.7 29.1 21.5 23.1 33.7 0.2 0.0 0.0 1264.4 0.1 0.0 0.0 0.0 0.0 26.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 2.6 0.1 0.2 0.2 0.0 0.0 146.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 98.7 0.1 0.0 0.3 0.0 2.7 0.0 0.1 0.0 41.2 0.0 11.1 0.0 742.4 1030.7 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.1 0.0 1.0 0.2 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.2;intestine: 30.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 240.7;Pancreatic endocrine cells: 164.5;Proximal enterocytes: 139.0;Squamous epithelial cells: 142.0;Urothelial cells: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.1;HaCaT: 35.0;HeLa: 33.9;hTERT-RPE1: 60.1;SiHa: 48.0;SK-MEL-30: 35.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB000349: , HPA052838: , HPA063327: AB_2684987" "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" 18.7 1.9 2.0 2.9 1.8 0.4 8.6 1.1 1.9 9.6 9.1 22.4 21.7 3.8 0.6 36.2 1.7 2.4 1.0 1.6 2.2 1.2 1.2 12.6 1.1 2.7 1.5 0.9 1.2 3.3 3.5 2.3 2.3 3.6 19.7 2.8 6.7 4.7 7.2 12.9 30.9 2.1 1.7 4.6 6.0 5.3 2.4 0.8 1.1 1.1 8.1 7.9 20.2 2.4 0.0 0.0 0.3 2.1 28.2 38.1 0.7 1.8 0.0 4.6 12.6 3.6 10.3 0.0 3.4 2.3 0.0 35.0 0.8 6.9 5.5 2.6 9.7 0.0 33.9 1.5 14.4 1.1 6.1 8.1 0.0 6.5 25.8 60.1 4.4 0.0 0.0 17.1 7.3 2.8 0.0 0.1 1.7 1.7 19.5 0.0 2.4 0.7 10.0 0.0 5.4 0.1 48.0 11.5 35.7 25.8 3.0 0.0 14.8 0.0 0.7 0.1 0.0 13.5 8.4 0.1 0.0 1.0 0.0 0.0 3.3 0.0 0.1 3.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.0 9.0 0.0 0.0 1.0 2.0 1.8 1.1 1.9 1.6 2.2 2.7 1.5 2.3 1.7 2.4 2.4 3.5 67.3 6.7 0.3 2.9 5.4 27.0 40.5 5.7 3.2 6.4 9.8 3.1 1.5 37.5 5.5 0.0 1.2 3.2 240.7 0.0 57.7 11.3 31.8 7.5 4.1 7.7 0.0 0.1 38.2 0.8 11.5 30.5 37.2 0.0 0.4 1.8 0.1 1.2 0.0 0.5 31.6 14.2 17.6 3.8 2.7 0.6 5.6 3.6 2.8 3.2 4.8 0.0 1.0 0.5 164.5 75.6 1.2 2.1 65.3 139.0 0.1 17.9 7.2 0.0 2.7 8.9 13.8 3.5 142.0 24.2 3.1 2.9 1.2 23.3 241.6 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 119.3 18.1 26.1 3.3 28.2 0.2 35.9 24.6 31.2 9.5 109.8 4.8 0.7 8.3 140.3 3.5 13.7 10.5 26.1 28.3 30.7 3.1 506.7 11.7 6.6 23.6 26.2 25.8 14.2 0.7 20.7 35.2 25.6 9.1 1.8 15.9 7.2 72.8 8.5 3.0 4.0 6.2 25.6 3.7 4.1 15.6 26.7 1.3 9.6 19.9 3.1 8.1 5.7 25.6 0.0 0.0 48.1 0.0 57.9 22.3 0.2 1.4 0.4 4.6 4.5 0.0 0.0 0.0 0.0 0.6 17.2 0.1 17.1 0.0 6.6 0.1 8.5 1.7 0.0 1.4 0.2 0.1 0.0 8.5 0.0 0.7 0.0 1.2 6.3 0.0 0.0 0.0 5.5 0.0 1.2 0.2 17.8 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 11.0 0.1 0.0 0.0 4.0 0.0 5.4 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 26.1 28.2 24.6 31.2 28.3 30.7 23.6 26.2 25.6 25.6 26.7 25.6 4.1 0.0 1.3 6.8 0.7 0.8 0.8 0.0 0.6 27.3 1.0 7.1 3.4 0.0 0.0 1.8 6.2 329.4 0.3 0.0 0.0 9.9 6.0 0.3 7.1 3.1 1.8 2.7 12.2 0.2 17.0 27.8 0.0 0.3 0.0 7.5 33.9 149.5 23.4 1.7 16.4 0.0 0.0 5.7 1.6 15.0 91.0 0.6 1.8 1.0 0.6 31.4 0.0 5.5 3.1 0.3 0.0 37.6 0.0 0.9 0.0 2.0 0.0 3.8 13.1 7.3 3.9 1.6 1.4 0.5 1.3 481.9 0.9 104.7 0.0 0.1 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cell line enhanced" "Detected in many" "BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 98.7 2.9 16.2 5.7 17.9 22.6 67.7 18.3 26.9 8.7 10.4 21.0 21.2 2.9 0.8 20.9 4.3 3.0 2.8 15.7 18.8 3.6 194.7 25.5 9.1 27.4 22.4 1.3 9.7 26.8 2.6 16.0 21.3 8.8 11.5 0.6 9.8 3.4 19.1 118.7 20.8 2.5 25.7 7.7 12.5 1.0 24.5 4.1 6.5 4.5 6.3 8.7 14.8 34.8 2.5 5.1 0.1 7.1 55.8 0.0 196.9 0.1 1.5 0.1 0.0 24.8 0.1 0.0 3.0 0.0 1.1 9.4 5.8 0.6 0.0 35.8 7.2 0.1 0.1 110.9 0.9 36.6 42.1 2.2 25.4 0.0 0.2 0.0 0.0 2.8 2.4 0.0 0.0 12.7 0.2 114.1 5.0 61.8 2.7 0.0 0.4 1.1 0.2 17.7 0.4 1.7 0.7 0.5 0.8 6.2 13.7 407.7 0.1 0.1 0.8 0.1 0.9 0.4 0.0 0.2 0.0 130.9 0.0 16.0 7.1 0.0 0.8 12.3 0.7 0.0 0.1 0.5 5.1 0.1 0.2 0.4 2.5 0.0 15.7 0.2 0.0 2.1 16.2 17.9 18.3 26.9 15.7 18.8 27.4 22.4 21.3 25.7 24.5 34.8 5.4 16.0 37.8 0.0 2.8 37.3 20.8 3.3 22.2 0.7 6.2 12.2 0.4 57.2 5.1 0.0 0.0 40.3 14.4 91.6 3.9 0.5 0.0 0.8 0.8 4.9 4.2 5.7 1.9 5.8 44.3 9.5 12.8 1.3 1.3 0.0 2.2 106.5 87.0 0.0 0.3 24.8 4.1 35.0 27.4 0.2 3.1 42.9 5.4 17.8 28.2 8.4 6.2 1.0 0.4 1.9 30.6 1.5 2.0 15.1 42.5 4.9 5.1 0.5 0.0 4.1 3.1 0.2 0.7 29.7 171.8 212.3 5.0 0.3 51.5 12.2 CHCHD10 "C22orf16, MIX17A, N27C7-4" ENSG00000250479 "Coiled-coil-helix-coiled-coil-helix domain containing 10" Q8WYQ3 22 23765834-23767972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1622.6;skeletal muscle: 1220.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1264.7;Distal tubular cells: 2498.5;Hepatocytes: 1879.9;Proximal enterocytes: 1501.3;Proximal tubular cells: 1437.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003440 Enhanced Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003440: AB_1078348" "unprognostic (3.88e-2)" "unprognostic (2.36e-3)" "unprognostic (8.90e-2)" "unprognostic (9.80e-2)" "unprognostic (7.68e-2)" "unprognostic (5.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "unprognostic (2.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" "prognostic favorable (2.15e-7)" "unprognostic (5.19e-3)" "unprognostic (2.06e-1)" "unprognostic (5.68e-3)" "unprognostic (2.62e-3)" 216.5 136.5 181.6 30.3 188.3 12.5 144.5 183.0 248.9 77.3 262.6 261.2 92.6 35.5 32.4 147.3 43.1 10.9 1622.6 176.6 190.5 409.5 789.7 56.9 28.6 182.2 182.2 29.0 118.0 220.0 112.3 11.9 187.6 106.4 76.2 63.1 148.3 50.5 1220.9 71.8 159.0 17.9 169.5 100.3 160.2 27.8 204.8 14.0 224.7 660.7 34.5 110.2 89.1 179.3 33.1 66.4 19.7 85.9 42.1 27.7 41.9 11.9 22.8 23.5 28.4 124.1 35.1 113.5 30.7 41.2 12.9 99.8 109.2 34.1 20.5 35.9 140.6 22.5 48.8 117.1 73.8 63.6 108.2 53.3 91.9 35.6 9.3 4.9 29.0 17.2 47.7 48.0 20.6 121.8 21.8 48.2 16.9 194.9 183.5 90.0 4.0 209.0 112.7 55.3 41.3 23.8 13.9 145.7 149.7 36.6 54.9 47.0 15.3 1.0 1.1 18.3 0.2 28.8 11.1 62.5 20.5 54.9 11.2 0.2 4.1 11.2 3.0 9.1 1.9 11.7 3.2 4.0 1.8 10.6 4.9 3.5 0.0 0.8 8.2 7.3 4.3 1.2 181.6 188.3 183.0 248.9 176.6 190.5 182.2 182.2 187.6 169.5 204.8 179.3 88.7 12.8 10.5 36.2 294.8 48.2 415.4 28.2 144.5 136.2 156.9 238.2 503.8 268.8 20.5 419.3 114.7 42.5 104.7 1264.7 2498.5 88.1 27.0 76.6 229.8 47.4 310.5 74.3 38.5 54.5 255.7 67.8 300.7 94.3 84.0 171.9 78.1 1879.9 647.5 99.3 37.6 860.9 26.4 262.1 127.5 18.0 48.7 243.1 373.5 15.9 107.8 188.5 25.7 17.1 17.4 45.9 890.1 29.3 297.3 192.4 1501.3 1437.4 10.0 287.8 124.9 254.0 200.4 32.3 43.4 459.3 43.9 105.2 123.0 216.0 952.4 470.1 CIDEA CIDE-A ENSG00000176194 "Cell death inducing DFFA like effector a" O60543 18 12254361-12277595 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "adipose tissue: 221.3;breast: 108.0" "Cell type enriched" "Detected in some" 78 "Breast glandular cells: 330.6" "Cancer enhanced" "Detected in some" "breast cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "hTEC/SVTERT24-B: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "unprognostic (2.96e-2)" "unprognostic (2.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (8.93e-3)" "unprognostic (3.20e-2)" "unprognostic (7.00e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-3)" "unprognostic (3.17e-2)" "unprognostic (7.67e-3)" "unprognostic (1.96e-1)" 221.3 3.7 2.3 0.2 3.2 0.0 108.0 2.8 5.2 3.5 1.7 1.5 0.0 0.0 0.0 4.8 0.0 1.2 1.9 2.7 1.8 0.2 0.2 0.0 0.3 2.4 2.2 0.0 0.9 0.0 0.0 0.0 2.7 0.1 0.9 0.1 4.3 0.0 1.0 9.3 2.1 0.2 2.2 0.0 1.0 0.1 2.0 0.2 0.5 4.6 0.2 1.1 5.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.8 5.2 2.7 1.8 2.4 2.2 2.7 2.2 2.0 3.0 1.9 0.0 0.0 0.7 0.5 0.1 0.1 0.3 0.0 0.2 330.6 3.8 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 1.0 0.0 0.2 0.3 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.2 0.6 0.6 1.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.4 0.3 0.7 1.0 0.0 0.3 0.5 0.0 0.8 CIDEC "CIDE-3, FLJ20871, Fsp27" ENSG00000187288 "Cell death inducing DFFA like effector c" Q96AQ7 3 9866711-9880255 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 740.3;breast: 492.9" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 219.4" "Group enriched" "Detected in many" 5 "breast cancer: 4.5;colorectal cancer: 1.4;liver cancer: 2.4;pancreatic cancer: 4.6;stomach cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 1683.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018837, HPA020553" Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA018837: AB_1846767, HPA020553: AB_1846769" "unprognostic (1.83e-2)" "unprognostic (3.08e-2)" "unprognostic (2.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-1)" "unprognostic (7.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-5)" "unprognostic (9.03e-2)" "unprognostic (1.81e-1)" "unprognostic (5.48e-3)" "unprognostic (8.14e-2)" "unprognostic (5.37e-5)" "unprognostic (9.47e-3)" "unprognostic (2.02e-1)" "unprognostic (7.46e-3)" "unprognostic (2.94e-2)" 740.3 5.6 0.1 1.1 0.2 0.0 492.9 0.0 0.4 1.2 0.0 15.9 68.9 4.6 0.3 0.7 2.2 5.0 9.5 0.1 0.1 2.1 10.0 0.2 1.2 0.1 0.2 0.4 7.4 0.1 0.2 0.0 0.2 2.3 3.9 0.0 16.2 3.7 6.1 18.1 89.8 1.6 0.1 0.2 7.4 0.9 0.2 1.5 3.9 11.6 0.0 13.3 4.8 0.2 0.0 0.2 0.0 0.0 1683.2 376.0 1.2 0.1 0.0 0.0 0.0 7.5 9.1 0.0 0.2 0.6 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 19.1 2.8 0.0 0.0 228.9 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.3 0.0 0.6 1.6 0.0 0.0 1.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 2.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 2.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 30.0 1.9 0.0 0.5 0.2 0.1 0.1 3.5 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 8.4 0.0 0.0 0.4 1.0 2.5 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 14.5 0.4 0.0 0.4 219.4 1.1 0.0 0.0 0.0 0.5 0.6 0.6 0.4 0.0 0.0 0.0 0.2 0.1 3.8 0.3 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 694.7;intestine: 653.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 2767.4;Distal enterocytes: 4691.8;Distal tubular cells: 2281.3;Horizontal cells: 5042.4;Muller glia cells: 3639.8;Rod photoreceptor cells: 3789.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 290.8" "Lineage enriched" "Detected in many" 18 "monocytes: 290.8" "Cell line enhanced" "Detected in many" "CACO-2: 455.8;HEK 293: 1399.8;SCLC-21H: 792.2;SH-SY5Y: 352.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favorable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 90.7 60.0 471.6 25.8 627.0 3.2 47.2 641.1 694.7 105.2 192.7 653.4 36.0 222.6 16.0 54.5 197.9 17.9 269.8 428.7 482.3 161.0 9.0 60.3 4.0 427.5 440.4 58.8 27.7 108.2 74.0 4.7 345.1 301.8 151.9 471.3 37.9 208.3 80.0 76.5 120.8 113.8 434.5 6.8 479.9 97.6 596.2 2.8 87.9 47.1 5.1 298.4 101.6 383.6 2.4 54.5 321.1 14.7 4.4 2.3 6.3 37.5 0.3 2.4 1.4 455.8 7.3 0.4 36.9 29.1 9.9 70.2 109.9 1.5 0.2 9.6 1399.8 111.0 242.1 165.4 16.6 0.7 87.9 14.7 0.6 3.9 0.8 3.3 0.0 5.1 198.7 3.7 4.8 20.0 2.3 3.9 109.1 48.3 213.6 13.9 6.8 275.9 65.9 2.5 792.2 352.2 65.3 10.6 25.2 21.6 21.1 40.9 2.2 1.5 56.3 4.7 147.3 21.1 2.7 7.2 6.4 2.1 14.1 2.4 0.5 14.6 0.3 28.5 0.4 0.0 0.2 0.1 16.4 0.2 0.1 0.5 1.0 0.2 290.8 0.0 0.7 6.0 471.6 627.0 641.1 694.7 428.7 482.3 427.5 440.4 345.1 434.5 596.2 383.6 14.8 195.5 103.5 515.8 13.5 153.7 296.2 257.6 56.3 2767.4 41.5 48.9 553.5 145.8 117.9 114.0 1909.9 4.4 3.4 4691.8 2281.3 127.6 445.8 773.2 205.7 60.8 467.1 9.9 178.0 42.5 11.7 96.6 359.4 408.5 28.6 476.1 74.6 9.2 8.2 5042.4 147.0 726.0 187.2 2.8 44.9 147.4 304.1 39.8 181.5 88.1 74.2 3639.8 0.0 93.5 161.2 131.4 1996.9 1089.3 6.6 279.8 9.5 118.0 456.1 3789.9 59.2 15.4 222.6 127.3 97.4 22.1 175.2 41.6 19.1 12.2 755.6 220.1 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.7;skeletal muscle: 289.7;tongue: 98.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 509.6;Cardiomyocytes: 285.7;Distal enterocytes: 164.2;Late spermatids: 93.8;Proximal enterocytes: 126.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;EFO-21: 9.2;HDLM-2: 4.7;REH: 11.9;U-266/70: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" 18.9 1.5 3.2 4.3 4.4 0.2 6.5 1.5 2.9 19.0 0.5 28.6 20.9 2.1 0.9 2.9 4.5 3.0 102.7 2.1 5.0 54.7 0.3 70.8 1.7 2.1 3.8 0.5 1.1 1.7 3.0 16.5 2.2 2.6 25.8 16.9 2.7 1.4 289.7 1.2 36.6 2.3 1.8 44.5 1.6 1.4 5.5 1.0 7.3 98.3 1.9 2.0 2.6 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 13.5 0.0 9.2 0.0 0.0 0.3 0.0 0.1 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.4 1.6 0.0 11.9 0.3 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 12.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.1 0.1 2.0 1.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.5 3.2 4.4 1.5 2.9 2.1 5.0 2.1 3.8 2.2 1.8 5.5 1.9 59.6 509.6 30.0 4.6 1.4 0.1 0.1 0.0 1.2 0.3 0.5 0.4 285.7 5.7 26.9 14.7 0.0 0.2 0.7 164.2 0.0 1.7 52.9 4.6 0.5 29.8 13.1 0.4 8.6 0.2 0.1 7.9 0.5 5.7 1.3 0.0 0.7 0.0 0.0 0.0 5.4 23.5 0.0 0.0 0.0 93.8 0.9 0.7 0.0 34.7 0.6 53.8 0.0 0.5 2.9 2.9 51.1 0.7 3.4 3.2 126.0 2.9 11.4 1.8 0.0 6.1 4.3 1.0 0.1 0.1 0.1 2.2 5.8 0.1 13.5 4.3 CLMP "ACAM, ASAM, FLJ22415" ENSG00000166250 "CXADR like membrane protein" Q9H6B4 11 123069872-123195248 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 63.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.7;Fibroblasts: 95.1;Inhibitory neurons: 31.9;Peritubular cells: 57.9;Skeletal myocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 124.8;BJ: 171.8;BJ hTERT+: 160.3;fHDF/TERT166: 126.6;hTEC/SVTERT24-B: 129.1;hTERT-HME1: 155.6;U-138 MG: 232.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.63e-2)" "unprognostic (6.65e-3)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (3.46e-2)" "unprognostic (9.42e-3)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (9.66e-3)" "unprognostic (3.25e-2)" "unprognostic (4.02e-3)" "unprognostic (3.87e-2)" "unprognostic (9.78e-8)" "unprognostic (3.88e-3)" "unprognostic (1.26e-1)" "unprognostic (1.19e-2)" "unprognostic (1.69e-2)" 63.2 6.5 0.9 14.7 0.8 0.4 24.5 7.8 2.7 20.5 3.6 41.1 7.3 30.3 4.3 10.1 18.4 23.1 12.9 5.3 0.4 6.0 0.4 8.1 7.4 4.2 2.1 9.1 2.0 0.2 1.9 26.3 1.8 7.4 10.6 0.9 5.4 8.5 1.7 6.5 17.3 36.3 2.0 8.1 16.0 2.6 2.1 0.8 2.4 3.4 5.0 16.7 14.0 5.2 3.0 3.3 7.5 15.2 124.8 108.1 45.5 171.8 160.3 23.9 43.8 7.4 0.2 0.0 0.4 126.6 82.4 0.1 0.3 45.5 27.3 0.9 0.3 0.0 7.1 0.1 40.7 0.0 0.1 61.0 30.6 129.1 155.6 59.7 11.7 0.1 0.0 0.4 33.3 0.1 0.0 0.2 17.4 0.0 20.2 0.1 2.5 0.1 12.6 0.0 20.5 50.3 0.0 0.4 0.1 3.2 0.6 0.0 43.3 232.7 2.3 96.0 21.6 0.1 0.0 0.1 63.1 0.0 7.5 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.9 0.8 7.8 2.7 5.3 0.4 4.2 2.1 1.8 2.0 2.1 5.2 2.3 0.0 3.9 2.0 0.2 1.5 0.3 2.4 0.0 3.8 1.2 14.6 5.1 0.0 0.4 0.0 0.0 9.8 0.3 0.1 0.0 1.9 0.7 2.4 75.7 1.4 6.7 0.0 26.5 1.3 20.4 95.1 0.0 1.4 0.0 5.3 2.2 0.0 3.6 1.7 31.9 0.5 0.0 0.0 1.9 0.7 20.8 0.9 0.0 4.7 0.0 0.5 0.0 1.0 3.6 0.9 0.0 57.9 0.6 2.0 0.1 0.1 0.2 1.1 0.0 65.0 8.5 0.1 0.1 0.4 1.0 10.4 1.1 2.2 0.3 0.5 CNTFR ENSG00000122756 "Ciliary neurotrophic factor receptor" P26992 9 34551432-34590140 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.1;skeletal muscle: 129.7" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Fibroblasts: 22.4;Muller glia cells: 83.6;Paneth cells: 30.6" "Cancer enhanced" "Detected in many" "glioma: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 109.3;SH-SY5Y: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025310 Approved NA NA 55000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "CAB025310: " "unprognostic (1.39e-1)" "unprognostic (9.40e-2)" "unprognostic (1.93e-2)" "unprognostic (1.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (9.70e-2)" "unprognostic (4.45e-3)" "unprognostic (1.72e-2)" "unprognostic (6.32e-2)" "unprognostic (4.99e-3)" "unprognostic (7.37e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" 60.0 10.3 67.2 1.3 91.9 0.0 49.7 81.5 69.0 29.7 16.3 7.6 3.3 2.8 2.6 3.9 13.0 6.3 39.0 54.3 58.5 2.9 12.4 3.8 1.0 57.0 82.8 5.2 2.2 0.2 9.7 5.2 62.2 11.0 2.2 13.9 11.3 7.7 129.7 11.5 8.7 0.7 49.8 30.6 7.0 7.2 94.1 5.1 13.7 35.1 0.4 5.6 17.1 47.4 0.0 0.0 109.3 0.0 13.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 3.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 52.1 0.1 0.1 0.0 1.0 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.2 91.9 81.5 69.0 54.3 58.5 57.0 82.8 62.2 49.8 94.1 47.4 0.9 0.0 0.0 57.1 0.0 3.6 1.1 0.0 1.2 19.3 11.9 1.5 1.3 8.6 0.0 0.0 6.2 0.9 0.1 6.5 1.9 0.1 4.3 0.1 2.4 0.3 0.0 0.0 4.1 0.0 0.6 22.4 0.0 0.1 0.0 0.0 2.5 1.4 1.4 3.3 9.3 0.5 0.0 0.0 2.7 1.9 9.9 0.1 3.6 2.8 0.0 83.6 0.0 15.1 0.5 0.0 30.6 2.2 0.3 0.2 14.1 0.1 0.0 3.2 0.0 1.2 1.9 5.5 19.8 0.3 2.4 2.3 0.2 0.0 0.5 0.3 COQ8A "ADCK3, CABC1, COQ8, SCAR9" ENSG00000163050 "Coenzyme Q8A" Q8NI60 1 226940286-226987544 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 1165.1;tongue: 484.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.9;Collecting duct cells: 33.1;Ductal cells: 21.2;Exocrine glandular cells: 32.7;Proximal tubular cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 82.0;RPMI-8226: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061662 Supported Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA061662: AB_2684578" "unprognostic (6.37e-3)" "unprognostic (2.09e-2)" "unprognostic (2.29e-1)" "unprognostic (9.06e-2)" "unprognostic (8.94e-2)" "unprognostic (2.49e-1)" "unprognostic (4.42e-2)" "unprognostic (3.50e-3)" "unprognostic (1.81e-1)" "unprognostic (4.02e-1)" "unprognostic (4.15e-3)" "unprognostic (8.67e-2)" "unprognostic (2.40e-2)" "unprognostic (9.24e-2)" "unprognostic (2.82e-1)" "unprognostic (8.88e-2)" "unprognostic (2.62e-1)" 63.9 123.8 7.1 10.3 8.0 26.1 35.8 17.3 8.1 16.5 16.1 30.8 29.9 15.9 0.5 32.2 24.6 19.7 123.5 7.1 5.6 14.4 35.7 9.6 12.7 8.9 5.4 34.1 93.8 6.4 5.3 6.5 9.8 18.5 6.4 1.3 32.7 11.7 1165.1 25.1 18.5 7.2 5.9 14.4 52.8 6.7 5.9 8.6 9.4 484.7 4.3 40.8 13.4 11.5 8.0 14.4 3.3 10.3 11.4 7.3 57.7 3.6 2.9 5.2 6.9 23.0 12.8 24.5 17.9 2.4 2.6 9.2 6.9 8.2 0.8 25.5 82.0 16.7 11.2 38.8 2.5 25.8 9.3 14.2 12.2 4.0 5.4 4.9 2.5 24.7 29.4 19.4 0.7 11.0 15.2 37.3 15.5 62.8 29.5 14.9 17.1 78.6 1.6 5.9 59.9 24.2 7.3 28.7 20.6 3.4 15.1 34.8 2.5 5.9 5.3 8.2 13.3 43.0 40.5 13.1 5.3 29.3 6.0 47.7 23.5 68.4 15.8 17.1 15.3 22.2 15.8 14.6 18.6 26.8 21.5 17.0 43.1 21.2 13.6 8.1 21.5 26.0 7.1 8.0 17.3 8.1 7.1 5.6 8.9 5.4 9.8 5.9 5.9 11.5 11.4 3.2 21.9 0.0 5.8 0.0 0.0 0.0 0.0 0.0 18.1 17.1 0.0 0.0 4.3 33.1 0.0 12.2 10.2 0.0 15.6 21.2 0.0 12.3 8.9 5.4 0.0 0.0 0.0 32.7 10.0 6.3 0.0 9.6 13.9 9.8 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 11.4 0.0 0.0 0.0 0.0 10.8 0.0 0.0 3.2 0.0 0.0 24.8 2.2 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 7.7 5.2 16.0 0.0 0.0 COX14 "C12orf62, MGC14288" ENSG00000178449 "Cytochrome c oxidase assembly factor COX14" Q96I36 12 50112082-50120457 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 835.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044618, HPA062014" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044618: AB_10960419, HPA062014: AB_2684657" "unprognostic (5.71e-2)" "unprognostic (1.86e-2)" "unprognostic (1.43e-1)" "unprognostic (4.04e-1)" "unprognostic (1.87e-2)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (4.20e-3)" "prognostic unfavorable (7.90e-4)" "unprognostic (7.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.09e-3)" "unprognostic (3.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-3)" 124.0 106.4 96.3 47.1 101.4 66.2 105.6 110.3 129.7 63.6 120.1 92.4 83.4 46.2 130.5 68.5 54.9 62.9 238.6 94.5 105.5 143.8 145.4 62.3 74.5 102.6 99.8 52.8 62.0 127.8 88.0 54.7 102.9 67.0 77.5 60.6 84.9 80.7 247.6 49.8 84.0 58.7 102.9 66.9 76.5 32.6 104.0 54.9 87.3 276.7 62.0 74.2 47.3 110.2 78.4 168.3 32.8 79.4 169.4 105.7 60.5 61.1 92.7 98.8 89.5 156.7 109.1 69.9 171.9 78.3 82.6 79.0 57.2 87.5 91.7 78.7 236.6 154.3 140.4 139.2 65.1 112.1 133.7 123.8 129.9 67.1 76.7 100.5 96.2 83.1 70.2 153.4 109.1 193.3 93.7 170.3 51.5 116.4 211.3 77.6 52.4 176.8 155.0 149.1 91.0 51.4 92.4 177.5 195.6 72.6 115.1 103.6 75.2 55.0 58.1 92.3 50.1 106.3 199.0 93.5 77.9 105.0 30.9 258.8 197.8 172.7 146.1 194.5 155.6 213.7 186.9 167.0 190.0 188.0 176.7 173.7 67.0 153.1 178.2 247.2 224.8 214.8 96.3 101.4 110.3 129.7 94.5 105.5 102.6 99.8 102.9 102.9 104.0 110.2 91.5 60.9 120.6 11.1 108.8 124.9 91.2 212.9 87.0 68.2 169.2 192.5 524.4 161.5 138.7 222.5 22.9 191.9 111.1 320.9 565.4 131.4 7.1 117.5 58.7 99.2 156.0 69.2 13.1 170.1 122.6 90.3 81.6 88.1 65.4 64.0 88.9 397.9 219.6 47.1 16.3 214.7 187.2 152.3 110.4 22.9 129.2 117.7 149.4 6.5 181.2 111.0 111.2 7.1 22.3 116.8 262.4 109.4 93.0 129.5 492.6 835.5 157.5 67.4 105.2 51.5 130.8 51.1 56.0 121.6 159.3 127.5 112.2 115.4 227.4 118.6 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.2;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in some" "B-cells: 32.6;Erythroid cells: 20.4;Kupffer cells: 59.1;Macrophages: 24.9;monocytes: 13.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 53.7;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.7" "Group enriched" "Detected in some" 9 "HL-60: 9.9;HMC-1: 21.8;NB-4: 9.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" 13.2 0.8 0.1 27.2 0.5 10.5 0.6 0.1 2.9 1.2 1.3 1.5 1.3 0.5 0.2 0.9 1.4 2.1 0.6 0.2 0.2 2.5 2.6 3.2 20.1 0.7 0.5 0.2 0.3 0.1 0.2 9.1 1.6 0.2 1.5 0.0 0.4 0.4 0.2 0.1 4.4 6.3 0.1 24.4 1.7 0.6 2.1 1.6 0.3 1.0 17.9 6.7 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 9.9 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.7 4.2 17.2 0.0 2.4 0.7 4.5 0.9 0.4 0.3 2.2 0.2 0.1 15.6 0.0 2.3 0.0 0.0 1.3 0.1 0.5 0.1 2.9 0.2 0.2 0.7 0.5 1.6 0.1 2.1 1.8 0.3 0.0 4.2 0.3 32.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.2 0.2 0.0 20.4 0.3 0.0 0.1 0.6 0.0 0.2 1.3 0.3 0.0 0.4 9.7 0.0 0.4 0.0 0.0 59.1 1.4 0.0 0.0 24.9 0.0 1.9 13.3 0.0 0.0 1.5 4.4 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.3 0.5 0.0 0.0 CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.5;tongue: 201.3" "Cell type enhanced" "Detected in many" "Early spermatids: 181.2;Late spermatids: 521.8;Proximal enterocytes: 136.4;Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Nucleoplasm,Nuclear membrane" NA NA 8100 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_2732427" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favorable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" 36.1 51.3 26.4 5.4 26.6 9.0 29.2 27.0 33.8 31.7 27.5 36.1 33.0 24.8 4.0 37.3 23.1 6.6 68.2 25.1 27.8 46.9 151.2 15.2 3.2 28.8 28.2 23.0 107.1 26.3 12.3 6.6 30.6 42.2 4.2 1.7 32.8 8.9 227.5 29.6 37.2 6.8 26.7 15.2 34.0 146.4 30.2 3.1 21.5 201.3 1.6 31.3 27.5 24.4 0.1 39.3 10.7 21.3 13.4 25.9 17.0 15.0 16.6 18.9 12.0 7.8 14.0 1.5 9.2 25.9 23.2 6.7 2.2 4.9 7.2 23.6 0.3 7.3 19.1 30.4 34.1 0.0 26.1 26.3 0.0 15.7 0.9 15.8 26.2 7.2 3.6 5.7 20.0 9.1 0.5 15.9 2.8 32.0 18.0 16.8 21.8 12.2 18.0 0.6 4.2 12.1 0.0 7.1 4.8 3.4 49.7 5.5 22.6 23.0 1.6 32.1 15.4 25.5 22.6 0.1 28.8 4.2 16.8 1.6 8.4 3.5 3.2 5.5 6.7 1.5 4.4 4.3 8.6 1.3 2.6 3.1 1.1 4.4 5.6 3.9 4.5 6.1 26.4 26.6 27.0 33.8 25.1 27.8 28.8 28.2 30.6 26.7 30.2 24.4 10.5 6.4 3.7 5.5 4.9 3.2 4.7 10.8 0.6 1.5 9.7 8.1 57.8 21.5 8.2 3.7 2.1 45.9 6.0 64.5 17.6 22.6 181.2 3.5 15.7 12.9 15.5 17.4 5.3 22.4 55.6 19.3 16.8 9.9 7.0 12.9 14.6 65.7 20.7 1.7 6.1 23.6 14.2 13.9 10.5 521.8 22.1 12.4 5.4 6.5 8.3 15.5 6.2 3.5 4.0 11.6 47.6 24.5 9.6 9.3 136.4 52.0 2.8 1.3 6.6 10.5 15.7 123.5 8.6 57.4 4.5 50.3 7.6 20.1 29.3 13.8 CRLS1 "C20orf155, CLS1, dJ967N21.6, GCD10" ENSG00000088766 "Cardiolipin synthase 1" Q9UJA2 20 6006093-6040053 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 169.5" "Cell type enhanced" "Detected in all" "Early spermatids: 264.2;Hepatocytes: 208.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 237.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.88e-1)" "unprognostic (8.56e-2)" "unprognostic (9.64e-3)" "unprognostic (1.89e-1)" "unprognostic (1.41e-2)" "unprognostic (2.65e-2)" "unprognostic (1.42e-1)" "unprognostic (2.00e-1)" "unprognostic (9.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-2)" "unprognostic (1.83e-2)" "unprognostic (1.85e-1)" "unprognostic (9.54e-2)" "prognostic favorable (8.02e-4)" 50.1 55.1 14.7 16.9 14.9 28.4 33.2 14.4 17.9 24.0 16.7 32.3 59.2 18.9 19.9 18.5 24.1 19.9 82.8 14.5 14.7 57.8 169.5 27.1 16.5 15.5 15.9 21.2 37.4 28.3 15.8 17.9 15.3 32.6 32.9 15.5 27.5 25.8 86.0 15.1 40.9 23.7 15.3 14.5 46.5 27.8 16.9 16.9 27.2 79.5 18.3 25.8 17.7 15.4 71.7 46.5 27.9 40.0 83.1 74.9 34.5 43.6 50.9 38.8 46.8 61.5 44.4 75.8 31.4 52.6 73.3 45.0 54.6 70.9 57.6 21.9 39.9 99.5 17.0 237.4 59.6 99.7 32.4 44.6 59.4 41.5 73.5 36.8 57.3 40.3 76.4 31.6 44.2 25.9 63.6 90.1 55.4 154.8 42.4 42.3 44.6 80.7 61.8 22.1 50.3 43.4 44.8 98.7 78.1 27.5 35.8 59.6 39.2 45.9 33.4 48.7 59.0 33.8 79.1 79.9 17.6 79.5 43.9 0.0 1.2 0.6 1.2 0.9 2.2 2.3 0.7 0.8 1.3 1.1 1.4 0.8 0.0 1.7 0.5 1.6 0.8 0.4 14.7 14.9 14.4 17.9 14.5 14.7 15.5 15.9 15.3 15.3 16.9 15.4 18.8 22.4 47.6 22.2 26.4 33.8 41.4 19.4 31.9 12.9 35.8 27.7 108.0 64.3 16.2 36.8 4.2 45.1 19.5 36.3 64.6 27.9 264.2 29.7 26.2 22.7 28.6 58.0 37.0 28.8 64.1 33.8 52.0 29.7 14.7 31.6 22.5 208.7 34.2 11.8 28.7 50.7 4.1 40.0 24.1 99.5 30.4 31.9 26.6 32.8 28.9 40.5 25.7 39.7 34.3 28.4 49.1 24.5 41.8 117.7 75.7 141.0 15.0 12.9 13.1 29.2 25.6 23.0 18.4 37.7 27.8 36.3 23.3 32.3 82.9 48.6 CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 550.1;tongue: 600.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 670000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB075750: AB_2665756, CAB075751: AB_2665757, CAB075752: AB_2665758, CAB075753: AB_2665759, CAB075754: AB_2665760, HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" 154.2 93.6 29.2 61.7 30.0 111.0 66.3 33.7 49.9 55.4 40.5 110.1 97.7 56.4 32.2 95.6 58.3 42.4 319.3 30.9 34.6 86.6 39.0 58.0 67.2 39.4 32.0 56.0 61.5 127.6 28.9 45.7 39.4 59.0 124.1 128.9 73.7 60.5 550.1 70.5 81.2 77.5 22.5 49.0 66.5 24.4 41.0 69.4 53.0 600.7 106.1 70.2 58.2 31.6 168.9 176.8 141.6 198.2 188.4 173.8 93.3 136.9 132.0 231.1 160.6 271.2 158.2 322.9 128.2 172.6 99.3 182.1 396.8 200.8 234.9 109.3 200.2 222.9 136.1 261.4 107.3 288.4 166.6 188.2 201.6 182.4 232.0 202.2 268.6 163.7 233.2 193.7 214.7 160.8 229.8 121.9 117.5 128.0 247.8 222.3 167.1 247.6 166.2 194.6 189.3 125.2 175.2 251.7 157.7 137.5 297.6 174.3 178.3 127.1 165.3 167.4 147.4 124.5 200.4 206.2 120.4 206.4 119.5 59.6 73.3 205.7 47.0 93.0 61.9 60.6 56.5 45.1 119.3 51.8 59.2 47.9 31.3 51.6 94.0 65.6 63.4 71.2 29.2 30.0 33.7 49.9 30.9 34.6 39.4 32.0 39.4 22.5 41.0 31.6 14.5 16.0 39.5 32.3 31.6 39.0 23.5 26.9 46.7 22.8 38.3 29.7 239.9 15.7 21.5 12.9 62.6 18.5 24.1 66.9 35.2 32.5 6.6 25.1 31.5 27.2 16.9 36.0 21.5 45.1 31.3 25.8 42.3 53.5 27.9 21.3 18.9 29.7 34.3 10.1 24.6 43.9 20.3 39.4 35.0 4.8 20.2 34.6 10.6 9.4 44.8 16.7 16.5 18.6 18.8 44.6 35.7 19.9 46.7 33.1 50.4 22.0 14.9 38.3 13.1 27.8 38.2 29.7 25.8 74.8 52.1 16.8 25.8 32.0 71.3 34.5 CST7 ENSG00000077984 "Cystatin F" O76096 20 24949269-24959928 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 1095.6" "Group enriched" "Detected in many" 9 "dendritic cells: 1094.4;Langerhans cells: 541.7;monocytes: 659.7;NK-cells: 1385.2;T-cells: 544.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 1287.0" "Group enriched" "Detected in all" 27 "granulocytes: 342.2;NK-cells: 655.3;T-cells: 1287.0" "Cell line enhanced" "Detected in some" "HL-60: 77.8;HMC-1: 204.6;NB-4: 212.1;U-937: 380.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Low region specificity" "Detected in all" HPA040442 Enhanced "Secreted to blood" NA NA 26000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA040442: AB_2676988" "prognostic favorable (6.55e-4)" "prognostic favorable (7.90e-4)" "unprognostic (9.37e-2)" "prognostic favorable (9.17e-6)" "unprognostic (2.38e-2)" "prognostic favorable (5.85e-5)" "unprognostic (1.00e-2)" "unprognostic (8.66e-2)" "unprognostic (2.84e-3)" "unprognostic (7.93e-2)" "unprognostic (5.05e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (4.37e-6)" "unprognostic (7.64e-2)" "unprognostic (3.38e-1)" "unprognostic (4.45e-1)" "unprognostic (7.62e-2)" 18.0 3.6 1.3 24.2 1.6 1095.6 5.7 2.8 5.1 4.5 1.7 5.7 5.9 4.6 4.8 5.4 10.4 17.7 5.6 1.5 1.4 5.4 12.7 49.3 73.4 2.4 1.4 2.5 3.9 1.0 2.2 4.4 2.0 4.3 5.1 0.2 6.6 2.0 1.9 4.5 13.9 5.0 1.6 148.1 8.7 1.7 1.6 17.3 5.6 4.4 16.4 19.2 5.2 1.4 0.3 0.6 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.3 1.7 0.0 0.4 0.0 77.8 204.6 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 2.8 0.0 0.2 2.0 212.1 0.1 0.0 0.2 0.5 7.7 0.1 0.0 0.1 0.3 0.2 0.0 0.1 1.0 0.1 0.0 13.3 0.2 0.1 0.8 0.2 0.5 0.1 0.1 0.2 0.1 380.4 0.1 74.3 3.0 10.4 1287.0 3.4 720.2 3.7 186.8 904.7 28.4 3.9 38.8 531.2 342.2 655.3 3.5 7.2 123.0 600.8 1.3 1.6 2.8 5.1 1.5 1.4 2.4 1.4 2.0 1.6 1.6 1.4 8.1 9.6 14.1 0.0 14.5 22.8 0.3 0.0 0.0 0.0 2.5 2.4 1.4 4.3 0.6 0.0 0.0 0.2 1094.4 0.3 0.0 1.3 0.0 1.3 0.7 3.2 0.0 46.7 0.0 3.7 0.1 5.2 11.2 1.2 60.0 0.0 11.0 3.8 1.4 0.0 0.0 0.1 0.0 16.2 541.7 0.0 0.0 61.9 24.9 1.9 659.7 0.0 1385.2 0.0 0.1 0.2 0.1 0.0 90.9 0.1 0.4 2.3 2.2 0.0 0.0 2.2 3.6 0.0 0.2 0.5 23.9 1.1 544.5 0.0 0.6 0.6 CTIF KIAA0427 ENSG00000134030 "Cap binding complex dependent translation initiation factor" O43310 18 48539031-48863217 "Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Excitatory neurons: 76.4;Inhibitory neurons: 80.6;Oligodendrocyte precursor cells: 75.9;Oligodendrocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016865, HPA024801" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA016865: AB_1852311, HPA024801: AB_1852312" "unprognostic (5.84e-2)" "unprognostic (5.86e-2)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.86e-2)" "unprognostic (1.95e-3)" "unprognostic (2.77e-3)" "unprognostic (1.35e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-1)" "unprognostic (2.34e-3)" "unprognostic (7.33e-3)" 35.3 20.0 15.7 3.3 13.9 2.0 24.3 10.7 23.2 14.0 0.0 26.0 2.5 21.5 2.6 11.4 16.3 7.5 24.8 16.0 15.5 11.1 24.8 14.3 1.3 20.7 17.4 28.0 9.8 4.6 12.4 4.3 23.3 13.9 1.6 7.4 11.0 5.4 15.8 14.0 9.9 7.0 9.1 6.7 19.6 7.3 19.0 1.4 10.7 4.3 1.0 26.1 12.6 16.7 3.2 3.4 4.5 5.8 11.3 6.0 2.5 15.9 13.2 12.4 11.2 3.5 1.9 0.0 3.5 22.0 5.2 6.7 3.3 9.0 5.3 0.0 2.7 1.4 7.9 8.4 21.6 2.6 4.5 8.4 14.5 7.8 13.8 8.9 8.9 4.1 4.0 9.8 8.0 1.7 0.9 2.0 2.2 3.4 2.8 1.6 5.2 4.2 3.7 4.3 9.6 9.7 5.6 6.0 4.5 3.8 3.8 3.1 18.1 11.4 10.5 3.4 2.9 3.3 4.2 0.0 10.1 1.6 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 13.9 10.7 23.2 16.0 15.5 20.7 17.4 23.3 9.1 19.0 16.7 7.3 35.3 3.7 94.7 1.9 3.3 2.1 3.5 2.8 25.6 11.2 8.4 16.0 5.7 5.6 7.3 16.7 1.9 0.8 4.6 7.9 5.1 11.1 1.7 7.7 8.5 3.5 0.4 76.4 4.8 2.8 13.1 7.1 3.6 4.5 19.5 7.5 23.0 4.2 11.8 80.6 3.5 4.1 6.4 2.7 19.3 25.1 5.0 3.6 30.0 1.5 3.6 3.1 75.9 59.7 5.7 2.7 50.8 4.8 3.0 5.9 5.8 4.7 8.8 6.6 8.8 9.4 2.3 1.8 3.5 2.3 1.2 0.7 34.7 3.3 3.3 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780059-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.9;lymphoid tissue: 158.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.2;Kupffer cells: 456.0;Macrophages: 469.3;monocytes: 396.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 276.3;intermediate monocyte: 261.6" "Group enriched" "Detected in many" 4 "dendritic cells: 90.9;granulocytes: 110.5;monocytes: 276.3" "Group enriched" "Detected in some" 5 "Daudi: 52.8;NB-4: 64.2;REH: 54.6;RPMI-8226: 210.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" 40.5 28.4 5.5 158.9 5.3 160.9 15.2 6.5 5.5 12.3 12.4 22.3 19.3 9.3 4.3 8.9 9.9 26.2 8.0 4.7 9.1 8.0 27.5 91.5 97.1 15.1 9.6 6.9 4.0 4.4 2.5 54.6 13.3 6.7 30.6 1.7 7.0 9.7 3.7 2.2 22.3 55.5 12.5 89.0 17.2 4.7 11.1 18.3 5.3 5.5 73.2 46.8 2.3 24.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 52.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.4 3.6 0.6 0.0 0.0 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.1 64.2 0.2 0.0 0.3 54.6 0.0 210.4 0.0 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 20.0 0.0 0.0 0.1 0.1 0.2 0.6 1.6 3.4 0.0 8.9 0.0 2.2 276.3 110.5 0.4 261.6 0.5 39.6 0.3 0.4 62.8 32.8 0.3 0.2 19.2 0.6 237.1 90.9 0.9 162.5 5.5 5.3 6.5 5.5 4.7 9.1 15.1 9.6 13.3 12.5 11.1 24.0 2.4 25.6 25.4 0.7 99.9 1.0 0.1 0.0 0.6 0.1 1.0 3.0 11.0 2.8 13.0 1.8 0.0 0.9 82.7 2.0 0.0 0.0 0.6 0.2 0.1 8.1 0.0 5.2 1.6 0.4 1.1 4.4 4.1 0.1 7.6 0.1 5.0 3.2 157.2 1.7 1.6 0.7 0.0 456.0 25.0 0.7 0.6 469.3 1.8 76.8 396.6 0.1 14.4 0.0 0.1 0.1 0.5 0.0 13.6 0.0 0.6 0.5 7.3 0.7 13.1 1.6 1.2 0.0 0.6 1.9 1.3 1.8 7.5 0.0 1.3 0.1 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90053633 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 290.1;liver: 272.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 399.2;Proximal tubular cells: 485.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol No No 120000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA023160: AB_1847585, HPA023162: AB_1847586, HPA023238: AB_1847587" "prognostic unfavorable (1.49e-4)" "unprognostic (5.76e-3)" "unprognostic (8.37e-3)" "unprognostic (6.13e-3)" "unprognostic (2.01e-1)" "unprognostic (4.45e-2)" "unprognostic (1.68e-2)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.79e-7)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "prognostic favorable (6.06e-4)" 60.2 136.8 12.4 9.6 14.4 24.9 54.4 12.5 14.4 29.4 22.2 65.0 20.2 28.0 14.9 52.6 26.1 7.4 290.1 12.7 13.2 103.5 272.3 34.2 15.0 12.2 13.1 35.5 44.4 13.2 32.6 5.9 12.1 28.6 18.8 8.0 42.8 6.5 121.8 43.3 61.0 9.1 12.5 47.1 44.5 52.3 15.4 10.2 33.0 34.4 13.9 31.1 35.8 12.8 13.1 7.9 19.6 16.1 8.0 17.3 5.2 13.2 12.9 5.9 8.2 2.8 13.4 7.7 5.3 15.1 4.1 6.8 7.7 11.1 11.0 12.6 1.2 18.4 13.6 14.5 11.6 8.7 4.4 12.0 7.0 7.6 10.7 10.1 17.4 16.5 21.3 15.5 20.7 16.3 12.5 7.6 1.5 9.1 24.9 7.4 5.8 13.4 23.4 43.9 1.3 10.6 13.0 81.1 7.7 1.1 10.7 7.4 20.1 11.4 6.2 12.9 6.0 10.5 7.5 12.8 8.6 12.0 10.8 3.9 9.1 6.2 7.1 10.2 7.9 7.4 6.9 8.6 8.8 4.6 8.1 7.8 15.2 3.9 9.3 3.9 9.6 5.8 12.4 14.4 12.5 14.4 12.7 13.2 12.2 13.1 12.1 12.5 15.4 12.8 66.1 76.9 59.4 72.5 52.9 41.3 70.6 180.2 35.3 11.4 51.1 57.4 268.3 82.9 96.4 71.7 2.1 50.2 57.6 119.0 399.2 137.8 165.3 68.2 65.5 60.0 104.8 77.4 27.2 92.5 49.0 60.2 61.2 40.6 50.0 81.3 47.8 244.8 115.1 32.0 55.9 105.9 116.0 95.2 82.7 52.6 85.4 85.1 85.4 29.0 107.1 52.5 74.2 66.9 35.0 87.5 111.6 51.6 67.8 30.3 250.3 485.2 69.0 7.6 72.3 54.5 61.7 157.5 24.6 68.6 41.1 41.0 64.4 135.1 139.6 86.8 DERL3 "C22orf14, derlin-3, FLJ43842, IZP6, MGC71803" ENSG00000099958 "Derlin 3" Q96Q80 22 23834503-23839128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.6;pancreas: 60.8;salivary gland: 51.1" "Cell type enriched" "Detected in many" 6 "Plasma cells: 1428.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "plasmacytoid DC: 187.4" "Lineage enriched" "Detected in many" 14 "dendritic cells: 187.4" "Cell line enhanced" "Detected in some" "Karpas-707: 26.9;RPMI-8226: 23.6;U-266/70: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB037234, HPA049306" Approved Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB037234: AB_1840802, HPA049306: " "unprognostic (2.01e-3)" "prognostic favorable (8.70e-5)" "unprognostic (9.72e-3)" "unprognostic (7.47e-2)" "unprognostic (9.77e-3)" "prognostic favorable (8.01e-4)" "unprognostic (2.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (4.74e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.76e-13)" "unprognostic (1.53e-2)" "unprognostic (4.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" 2.6 3.2 1.4 4.3 1.4 1.8 5.4 1.3 2.2 6.1 1.9 30.6 10.0 3.7 0.2 4.3 7.1 2.3 7.7 1.3 1.6 5.7 9.1 9.2 9.2 1.8 2.2 2.0 60.8 0.8 8.1 0.8 1.7 3.3 10.9 0.2 51.1 3.8 2.7 0.8 33.7 0.7 1.7 61.6 29.4 24.8 1.7 1.6 14.6 0.2 17.6 3.6 2.3 1.5 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.5 4.8 0.9 0.0 1.4 0.0 1.1 1.3 0.0 0.5 4.8 0.4 4.6 0.0 0.7 3.2 0.6 0.0 0.2 0.5 0.0 0.1 0.1 0.5 0.8 26.9 0.0 0.0 1.3 2.2 1.0 2.3 0.3 4.2 0.0 23.6 0.9 0.3 0.6 0.1 0.1 0.0 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.4 0.1 48.5 6.3 8.3 0.8 6.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 13.8 0.0 0.0 0.0 12.4 0.1 0.0 0.1 0.0 0.0 187.4 0.0 1.3 1.4 1.4 1.3 2.2 1.3 1.6 1.8 2.2 1.7 1.7 1.7 1.5 0.5 0.0 1.1 0.3 183.8 1.8 1.5 3.7 0.6 1.1 19.3 1.8 3.5 1.5 4.1 0.0 2.1 0.8 141.7 2.7 0.0 0.5 113.2 33.8 0.9 1.1 1.8 8.2 0.3 5.8 6.2 2.2 7.7 1.7 2.5 15.7 4.6 7.8 3.4 0.0 1.7 7.9 4.1 2.2 2.1 158.2 2.5 5.4 224.1 1.9 0.5 0.8 0.0 1.0 0.5 1.1 0.5 4.1 1428.8 2.5 0.8 0.5 30.3 0.6 0.0 0.8 2.6 67.0 32.9 1.3 2.0 15.5 17.9 2.1 10.7 2.0 DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 40.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 213.5;Proximal enterocytes: 700.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 18.4;PC-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Nucleoli, Nucleoli rim" "CAB032853: AB_2090798" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (5.10e-2)" "unprognostic (2.78e-2)" "unprognostic (6.88e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-3)" "unprognostic (3.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-3)" 15.0 24.7 4.6 1.8 4.6 5.1 11.8 5.5 5.6 6.1 4.1 16.7 37.0 5.6 1.0 8.6 5.1 2.0 11.7 4.7 4.1 7.9 16.5 6.9 1.8 4.5 4.6 4.3 6.5 3.9 6.5 1.5 4.2 6.6 4.2 1.6 7.4 2.4 11.7 6.9 40.6 1.6 4.1 9.3 8.7 14.7 4.4 2.3 7.4 3.5 1.4 6.7 6.4 4.5 5.2 4.9 2.2 4.1 3.5 1.5 2.9 3.4 3.1 2.9 2.0 11.2 3.1 2.1 12.4 1.9 1.6 4.0 1.8 4.3 0.6 3.7 5.1 3.3 4.2 18.4 2.5 1.0 3.4 2.1 3.2 2.0 2.1 2.1 2.3 7.3 2.9 5.2 1.9 3.7 6.8 4.1 1.1 10.9 21.2 7.7 0.9 3.4 2.8 2.5 2.6 4.2 4.7 5.2 2.3 0.8 2.9 3.3 2.0 1.6 5.6 3.6 2.8 2.3 0.6 0.8 1.8 6.3 3.2 0.0 0.4 0.7 0.2 0.3 0.4 0.1 0.2 0.2 0.5 0.1 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.2 4.6 4.6 5.5 5.6 4.7 4.1 4.5 4.6 4.2 4.1 4.4 4.5 34.0 16.0 19.0 15.7 8.5 8.0 12.5 6.3 4.0 24.6 21.6 16.0 20.8 12.8 8.7 18.4 29.2 11.3 17.6 213.5 1.9 9.4 19.2 12.3 13.7 26.5 23.4 17.7 11.2 11.9 10.3 9.3 48.4 21.3 7.0 23.9 12.5 57.4 18.8 18.5 12.8 93.6 4.1 25.5 11.8 25.8 6.8 22.8 5.4 8.4 9.2 21.3 4.1 17.6 7.0 13.3 113.4 6.8 18.8 8.1 700.1 7.4 5.6 23.6 0.0 11.9 12.3 27.7 17.4 12.3 9.2 16.4 12.3 41.1 108.0 20.7 DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 476.0;breast: 133.6;liver: 331.8;skin 1: 151.5" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Hepatocytes: 116.4;Late spermatids: 64.1;Spermatocytes: 53.9;Spermatogonia: 53.5" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 137.7;neutrophil: 348.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 348.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.4;HDLM-2: 62.5;Hep G2: 64.9;OE19: 124.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 22.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" 476.0 5.1 5.8 19.4 11.7 7.2 133.6 2.9 6.1 2.6 5.3 9.0 14.5 1.2 1.8 24.1 2.1 5.8 11.7 5.7 6.4 3.4 331.8 5.6 4.0 3.7 3.9 1.8 4.6 2.1 1.6 1.5 5.5 2.2 4.9 0.6 10.5 1.6 4.1 151.5 16.5 2.8 3.4 15.0 12.8 38.1 6.9 4.3 8.8 5.6 18.2 21.3 12.6 5.1 13.3 6.4 0.4 11.2 80.4 6.4 1.0 1.3 1.7 1.6 1.0 46.6 13.5 21.1 16.8 0.3 11.9 0.5 1.8 6.5 4.4 62.5 1.2 1.5 4.0 64.9 0.9 7.4 7.2 26.8 33.6 7.3 10.6 4.4 1.2 20.9 1.2 27.6 0.7 8.5 5.1 16.7 3.6 124.0 31.5 0.0 0.1 24.8 1.2 35.8 22.6 1.4 12.3 1.9 2.9 2.7 4.4 26.6 1.6 14.1 7.0 0.3 9.1 16.3 40.0 28.8 10.2 23.7 25.3 19.4 22.1 137.7 0.0 4.4 0.4 7.4 0.4 0.0 6.1 7.6 0.1 0.2 348.6 0.0 5.0 1.8 0.0 5.7 5.8 11.7 2.9 6.1 5.7 6.4 3.7 3.9 5.5 3.4 6.9 5.1 3.2 6.4 5.4 0.3 5.0 1.1 0.9 3.0 0.6 0.9 5.2 7.0 3.5 0.0 2.7 0.0 2.1 0.5 0.3 0.6 0.0 1.7 259.3 3.3 0.2 0.5 1.2 2.7 2.9 0.5 0.1 0.7 10.7 0.2 0.0 2.1 2.9 116.4 2.2 1.7 1.3 4.8 0.0 4.1 13.1 64.1 2.1 4.2 1.8 0.0 4.0 0.4 0.0 0.0 1.0 3.7 2.2 0.7 0.9 2.8 1.2 2.2 3.4 0.0 6.6 0.6 1.0 53.9 53.5 0.3 8.0 0.8 0.5 0.2 3.0 15.7 DHDDS "DS, FLJ13102, hCIT, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471306 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant, Epilepsy, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 256.5;Early spermatids: 99.1;Rod photoreceptor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA026721: AB_1847643, HPA026727: AB_1847644" "unprognostic (1.11e-2)" "unprognostic (5.43e-2)" "unprognostic (5.12e-2)" "unprognostic (9.81e-2)" "unprognostic (6.71e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-3)" "unprognostic (3.81e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "prognostic favorable (4.08e-7)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.22e-1)" "unprognostic (2.95e-1)" 57.3 19.6 12.3 18.9 11.8 12.4 22.7 32.5 14.0 14.6 14.6 37.3 19.1 13.5 38.5 26.3 12.9 15.9 19.8 12.8 13.3 25.5 22.0 13.9 17.6 15.5 16.9 11.4 18.5 39.8 20.9 12.6 18.8 14.1 38.8 37.8 43.3 14.0 13.5 21.2 18.2 18.4 9.0 14.1 23.3 12.3 14.1 14.1 19.1 11.8 20.8 18.1 14.4 12.2 34.2 24.8 20.6 23.8 36.1 28.2 28.4 54.9 33.4 44.0 41.6 37.4 34.6 38.4 33.3 57.2 30.0 24.1 25.4 42.8 42.9 22.7 13.9 38.0 66.9 30.8 39.3 41.4 51.5 40.3 27.6 59.1 32.2 29.4 51.2 26.7 27.3 41.0 39.7 19.4 23.1 20.2 26.3 53.1 36.2 25.3 33.4 31.2 25.4 28.8 24.4 19.4 36.4 38.0 26.6 26.8 29.8 20.9 63.0 30.1 26.3 60.4 32.0 48.1 72.4 39.5 43.0 54.0 26.8 9.4 16.1 9.6 13.8 23.6 9.8 13.2 9.0 9.1 13.6 10.2 7.4 10.9 13.0 10.1 23.1 11.5 8.3 10.5 12.3 11.8 32.5 14.0 12.8 13.3 15.5 16.9 18.8 9.0 14.1 12.2 9.4 9.6 7.8 7.8 13.5 4.6 9.6 12.0 10.8 29.6 9.6 7.4 15.5 15.7 13.8 14.7 256.5 18.3 13.7 76.3 11.7 19.3 99.1 11.6 12.9 11.1 20.9 5.7 26.9 14.5 23.4 11.1 33.6 20.0 19.0 14.4 10.0 13.2 24.5 15.2 28.5 46.3 14.2 11.5 7.1 23.4 10.5 10.5 10.6 10.3 34.4 16.3 14.4 9.0 11.4 17.6 40.3 7.5 18.7 10.6 24.7 29.3 11.5 106.1 0.0 8.4 14.5 13.2 13.5 12.4 5.1 25.4 10.3 15.8 26.0 12.2 DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "intestine: 216.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 317.3;Paneth cells: 154.2;Proximal enterocytes: 527.9;Undifferentiated cells: 148.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" NA NA 42000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 56: Intestine - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Golgi apparatus" "HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209" "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" 10.0 10.5 6.9 5.4 7.9 4.4 10.9 6.7 9.8 9.5 9.0 74.3 216.0 5.7 1.9 14.6 7.3 2.4 17.2 8.6 9.0 21.9 14.8 4.3 2.4 7.4 7.5 5.1 15.4 9.5 13.3 2.0 7.9 8.0 57.1 22.4 10.3 4.5 16.7 14.4 177.0 6.3 6.6 4.7 11.7 17.0 8.2 2.1 11.9 9.9 3.6 6.8 10.5 7.7 13.9 10.0 3.6 13.8 1.2 2.5 10.6 3.8 2.6 11.9 10.7 22.2 10.1 0.8 1.9 4.0 4.8 13.9 11.5 6.7 10.5 7.1 15.2 3.7 10.1 35.6 5.5 3.0 1.2 2.2 7.3 8.6 6.5 1.9 8.8 11.2 36.1 9.3 5.9 12.5 12.6 5.5 4.5 14.2 0.4 15.2 12.8 22.0 9.9 11.4 10.4 4.9 16.0 12.9 33.3 6.6 19.1 3.6 4.8 1.6 18.2 7.6 10.0 14.1 16.7 4.4 6.5 9.3 5.5 0.1 0.1 0.4 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.0 6.9 7.9 6.7 9.8 8.6 9.0 7.4 7.5 7.9 6.6 8.2 7.7 9.1 0.0 1.5 4.2 3.3 4.2 8.9 2.8 4.0 20.7 14.6 13.3 9.6 2.8 2.4 7.3 129.3 7.9 1.4 317.3 58.7 10.7 22.9 10.2 5.0 6.7 12.1 31.5 8.2 11.4 4.7 3.4 8.6 6.8 0.0 5.3 5.3 12.7 3.5 16.8 9.6 72.2 2.0 1.9 4.2 30.5 4.1 2.6 19.6 2.8 3.6 15.8 1.0 4.0 2.0 7.5 154.2 5.3 9.1 11.7 527.9 43.1 3.8 71.0 0.0 5.9 5.9 27.7 6.5 12.0 6.0 7.0 3.1 9.3 148.5 15.2 DIAPH2 "DIA, DIA2, POF, POF2" ENSG00000147202 "Diaphanous related formin 2" O60879 X 96684663-97604997 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.0;Late spermatids: 177.8;Microglial cells: 301.7;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005647, CAB015461, CAB068183, CAB068184" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum, Vesicles" Nucleoli "CAB015461: AB_831223, CAB068183: AB_2665693, CAB068184: AB_2665694, HPA005647: AB_1078657" "unprognostic (5.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (2.16e-5)" "unprognostic (1.58e-1)" "unprognostic (6.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.41e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.12e-4)" "unprognostic (3.39e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (6.44e-2)" "unprognostic (3.11e-2)" "unprognostic (6.99e-3)" "unprognostic (6.08e-3)" 10.7 3.3 3.7 6.4 6.4 17.7 7.0 0.0 4.3 10.6 17.3 8.6 4.3 5.5 3.5 7.7 6.7 5.7 5.4 6.4 3.1 3.1 12.3 8.2 3.8 0.6 0.9 7.7 4.9 7.0 2.0 12.5 1.0 6.1 8.7 3.0 6.6 7.6 12.0 5.3 5.3 7.4 0.2 3.8 7.4 9.4 1.5 6.0 3.9 9.1 3.9 7.4 9.8 1.8 0.0 6.5 3.1 6.3 17.1 28.3 0.0 11.2 11.8 5.9 12.4 5.5 12.3 18.5 8.7 9.7 11.3 0.0 16.6 1.7 7.6 0.5 9.5 0.0 7.4 5.9 14.2 24.3 8.2 14.3 6.0 8.0 24.6 8.0 11.6 13.6 0.0 14.9 11.2 5.3 9.2 10.0 24.4 0.1 9.4 0.0 16.5 0.0 3.4 9.8 0.0 6.3 0.0 3.2 9.0 18.8 2.7 13.2 14.8 12.6 5.8 10.6 7.3 0.2 0.0 15.3 10.7 24.1 7.6 0.0 3.1 3.3 1.1 2.8 0.9 1.7 1.2 1.4 2.3 1.3 0.8 0.7 0.3 0.7 2.5 2.2 0.7 0.6 3.7 6.4 0.0 4.3 6.4 3.1 0.6 0.9 1.0 0.2 1.5 1.8 61.7 32.1 51.1 21.2 18.8 10.8 6.8 11.9 11.4 5.5 9.9 8.1 20.2 15.7 15.0 20.2 0.0 65.2 21.5 36.6 7.9 18.6 80.5 51.2 46.2 31.2 24.6 6.1 171.0 23.4 16.8 35.2 41.8 41.7 7.6 36.1 8.2 26.1 21.0 0.0 90.0 32.3 4.1 29.6 19.3 177.8 45.1 34.7 8.8 301.7 32.7 13.0 10.3 281.0 41.2 38.4 39.3 20.3 11.6 8.0 11.9 9.4 57.1 13.7 26.3 46.7 32.7 7.5 12.9 17.6 18.3 118.3 19.0 19.0 32.5 6.0 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DMTN "DMT, EPB49" ENSG00000158856 "Dematin actin binding protein" Q08495 8 22048995-22082527 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 192.5" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 3.8;memory CD8 T-cell: 1.6;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.5;neutrophil: 1.2;T-reg: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;T-cells: 3.8" "Cell line enhanced" "Detected in many" "A549: 68.9;HEL: 225.9;Hep G2: 63.9;HMC-1: 65.6;OE19: 67.3;RPTEC TERT1: 87.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024290, HPA058487" Uncertain NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA024290: AB_1847601, HPA058487: " "unprognostic (6.74e-2)" "unprognostic (1.51e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (7.92e-5)" "unprognostic (2.88e-1)" "unprognostic (3.85e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-2)" "unprognostic (2.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.97e-1)" "prognostic favorable (3.85e-9)" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "unprognostic (8.07e-2)" 35.7 29.8 104.2 6.1 134.6 136.6 21.8 0.0 192.5 13.5 0.0 33.1 9.2 15.3 14.4 18.9 30.4 13.5 71.5 142.1 36.9 67.5 28.2 20.1 3.4 27.0 14.0 3.4 29.6 54.9 109.6 7.4 27.1 25.0 15.2 23.0 22.9 20.4 66.4 24.3 14.0 14.0 0.0 19.3 23.8 11.7 32.4 3.0 39.1 41.4 3.7 12.9 12.4 90.5 44.1 68.9 0.5 1.4 1.1 0.3 5.4 4.6 4.3 14.5 4.3 29.9 26.7 0.4 43.8 0.8 0.9 14.8 2.1 2.7 6.5 0.4 13.0 225.9 5.3 63.9 1.3 0.1 65.6 0.7 29.3 0.2 0.3 8.5 14.7 2.0 21.7 2.2 0.1 18.9 5.7 0.5 1.8 67.3 6.1 0.0 0.6 3.1 87.2 12.3 15.6 21.8 7.3 0.9 3.2 3.5 11.2 2.2 26.1 0.0 22.0 0.3 24.0 0.1 0.2 0.7 0.3 0.2 15.4 0.0 0.1 0.2 1.7 0.0 1.7 0.0 3.8 1.6 0.1 0.0 1.5 1.5 1.2 0.0 0.0 0.3 3.3 9.3 104.2 134.6 0.0 192.5 142.1 36.9 27.0 14.0 27.1 0.0 32.4 90.5 9.3 3.2 10.7 10.7 1.5 2.3 4.0 3.9 1.2 34.6 9.9 5.7 37.8 0.0 5.1 7.3 12.5 0.1 2.7 15.3 19.6 11.4 12.7 11.2 1.7 10.2 20.5 248.6 45.7 11.4 1.7 2.4 7.7 12.7 0.0 4.1 3.9 15.8 0.5 28.6 29.7 8.7 0.0 1.0 1.6 7.7 0.3 44.5 14.2 5.6 1.3 2.6 0.0 1.5 4.3 18.2 10.0 2.6 1.4 3.7 1.8 29.6 9.3 7.3 0.0 1.4 5.7 1.4 2.4 3.8 5.7 0.1 6.4 0.3 13.3 4.8 DNAH9 "DNAH17L, Dnahc9, DNAL1, DYH9, HL-20, HL20, KIAA0357" ENSG00000007174 "Dynein axonemal heavy chain 9" Q9NYC9 17 11598470-11969748 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 28.2;choroid plexus: 27.6;fallopian tube: 35.4" "Cell type enhanced" "Detected in many" "Early spermatids: 48.7;Endometrial ciliated cells: 97.5;Excitatory neurons: 26.8;Late spermatids: 56.5;Respiratory ciliated cells: 110.5" "Group enriched" "Detected in some" 4 "endometrial cancer: 1.1;glioma: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 3.1;WM-115: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052641 Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA052641: AB_2681895" "unprognostic (4.16e-3)" "unprognostic (3.67e-2)" "unprognostic (9.31e-2)" "prognostic favorable (6.79e-5)" "unprognostic (8.37e-3)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-1)" "unprognostic (7.35e-2)" "unprognostic (1.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.93e-1)" "unprognostic (1.14e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-3)" "unprognostic (5.31e-2)" 2.1 0.8 9.7 0.3 8.1 0.0 1.5 9.2 8.0 1.7 27.6 0.2 0.0 1.4 2.2 0.1 35.4 0.4 0.2 12.1 10.4 1.7 0.1 2.8 0.0 24.0 28.2 1.4 1.8 3.6 3.2 0.3 18.1 0.8 0.0 6.6 0.3 2.0 0.2 0.3 0.1 0.5 19.5 0.1 0.3 6.3 12.1 0.1 0.9 0.0 0.0 0.3 0.3 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 8.1 9.2 8.0 12.1 10.4 24.0 28.2 18.1 19.5 12.1 11.6 0.1 3.2 1.1 8.5 0.0 0.8 0.9 3.6 1.2 2.0 0.2 0.4 1.7 0.0 6.1 3.7 2.1 0.0 0.0 0.6 1.9 1.4 48.7 97.5 2.0 0.3 0.0 0.0 26.8 0.2 0.0 1.5 0.0 2.1 1.3 1.2 0.0 0.0 0.1 0.0 17.6 0.2 2.0 0.0 0.4 56.5 0.6 0.2 0.0 3.7 0.0 1.8 0.0 11.1 8.3 0.1 0.0 3.0 0.1 0.6 0.0 0.2 110.5 8.2 0.0 1.5 2.5 5.3 2.4 0.6 1.1 0.1 0.3 1.4 0.0 0.6 DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "dendritic cells: 130.6;Hofbauer cells: 131.8;Kupffer cells: 171.8;Langerhans cells: 288.4;Macrophages: 181.5;NK-cells: 344.0;T-cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 25.3;HEL: 54.3;HMC-1: 119.8;JURKAT: 22.3;THP-1: 43.1;U-937: 42.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" 9.5 5.0 1.1 26.5 1.2 19.5 5.0 1.2 2.3 1.9 2.5 5.5 7.0 2.2 0.5 2.3 3.5 6.5 3.5 1.3 1.3 3.0 6.1 25.6 26.3 1.4 1.5 1.4 1.9 0.5 1.1 7.9 1.5 2.3 3.6 0.0 3.4 1.5 2.0 2.3 9.5 6.9 1.2 40.9 6.8 1.6 4.5 16.4 2.4 1.6 7.8 8.4 2.3 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 54.3 0.0 0.1 0.0 0.4 119.8 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.8 5.0 0.0 0.0 0.9 8.7 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.3 1.4 42.0 0.2 577.6 484.3 1565.6 398.3 624.0 184.5 14.5 274.3 304.8 421.9 6.6 151.0 185.9 37.2 307.6 580.7 7.6 597.2 810.3 1.1 1.2 1.2 2.3 1.3 1.3 1.4 1.5 1.5 1.2 4.5 1.5 2.0 3.2 18.1 0.0 13.2 11.5 0.6 0.0 0.0 0.0 1.2 1.8 2.1 0.0 1.3 3.7 0.0 0.7 130.6 0.3 0.0 0.1 0.2 0.2 0.5 2.8 0.0 10.5 0.1 0.0 1.0 2.6 3.1 0.4 36.3 0.1 5.7 1.1 131.8 0.0 0.0 0.2 0.0 171.8 288.4 0.6 0.3 181.5 19.6 0.0 74.8 0.0 344.0 0.0 0.0 0.0 0.0 0.0 15.4 0.2 0.0 0.7 1.5 0.0 0.0 0.6 2.5 0.2 4.3 0.7 8.5 1.0 147.4 0.0 0.2 0.8 DTX1 "hDx-1, RNF140" ENSG00000135144 "Deltex E3 ubiquitin ligase 1" Q86Y01 12 113056709-113098028 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;lymphoid tissue: 11.8" "Group enriched" "Detected in many" 6 "Astrocytes: 48.3;Horizontal cells: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Daudi: 109.1;REH: 45.1;U-698: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051249, HPA055275" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA051249: , HPA055275: AB_2682769" "unprognostic (2.13e-3)" "unprognostic (3.20e-3)" "unprognostic (4.24e-4)" "unprognostic (2.01e-1)" "unprognostic (7.48e-3)" "unprognostic (1.59e-3)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (9.55e-2)" "unprognostic (6.87e-2)" "unprognostic (2.19e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.41e-2)" "unprognostic (4.70e-1)" "unprognostic (1.63e-1)" "unprognostic (4.78e-3)" 9.0 1.7 6.5 5.7 6.8 2.7 6.4 3.2 5.9 2.4 0.2 0.8 1.3 1.5 0.3 0.9 1.8 0.8 1.2 5.2 11.1 3.5 8.9 0.8 11.1 5.2 8.8 0.4 1.6 0.0 3.3 0.3 5.1 0.8 0.1 2.9 2.6 0.3 0.5 1.0 3.5 0.3 3.7 11.8 0.9 1.9 10.5 0.5 2.2 0.1 6.0 0.5 0.6 2.4 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 109.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.3 4.6 0.0 2.0 0.2 0.0 45.1 0.2 2.6 0.0 0.0 2.7 7.1 0.4 0.4 2.5 0.0 0.1 0.2 1.2 0.0 4.0 0.0 0.1 0.5 0.2 110.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.5 6.8 3.2 5.9 5.2 11.1 5.2 8.8 5.1 3.7 10.5 2.4 0.7 0.0 0.0 48.3 8.8 1.0 0.0 0.0 0.0 4.7 0.2 0.6 0.7 0.0 0.0 1.8 8.4 0.0 0.3 0.1 7.9 2.5 0.7 0.7 17.5 1.7 0.0 0.0 10.6 0.0 0.0 4.5 0.5 0.4 7.0 0.0 0.4 12.4 0.8 171.6 13.8 0.1 0.0 0.3 0.6 1.7 7.8 0.2 3.6 2.8 0.0 11.4 2.1 13.0 1.0 0.2 0.1 7.5 2.5 0.0 0.0 0.2 0.0 2.8 0.0 0.4 1.3 0.8 2.4 0.0 0.4 0.0 2.2 0.8 0.0 0.0 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.9;skeletal muscle: 906.9" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 796.9;Proximal tubular cells: 880.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 720000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" 216.0 343.0 51.2 47.6 53.7 62.3 194.2 54.1 60.3 124.9 58.6 232.9 93.5 115.3 32.3 168.4 114.0 66.8 749.9 49.3 52.5 271.6 556.1 122.1 67.8 51.8 51.8 107.2 141.4 56.0 77.1 67.1 53.4 99.5 99.9 12.8 138.6 43.3 906.9 149.0 167.4 59.7 50.6 192.3 180.5 100.7 55.0 51.0 117.9 455.1 65.7 142.4 132.4 53.3 64.0 273.8 42.0 68.8 161.0 82.0 61.8 31.7 53.2 26.6 27.1 178.8 124.8 98.6 117.2 72.8 24.1 30.1 70.9 72.9 21.1 345.3 37.7 120.7 76.5 146.1 161.3 131.9 116.9 109.0 186.6 35.1 61.2 52.3 63.4 127.3 58.4 160.8 59.6 120.0 91.8 82.2 27.8 278.8 65.9 101.8 126.2 199.0 168.7 142.6 51.4 67.2 161.0 77.1 86.5 27.3 106.4 288.4 53.7 45.5 39.3 46.5 29.6 121.0 153.2 96.4 71.4 164.9 90.7 316.1 312.9 268.0 253.6 248.2 237.2 368.4 243.5 249.1 308.6 361.3 216.5 242.4 41.6 342.7 212.8 221.5 391.8 541.8 51.2 53.7 54.1 60.3 49.3 52.5 51.8 51.8 53.4 50.6 55.0 53.3 125.4 86.6 104.7 13.1 111.1 82.2 220.0 320.8 80.8 22.4 124.0 143.8 302.7 205.9 203.2 145.3 16.7 796.9 103.4 257.7 510.6 195.4 64.5 95.7 56.9 96.4 189.2 99.9 7.1 90.1 370.6 104.1 112.7 77.0 120.9 177.6 90.7 549.4 277.6 37.0 8.6 298.9 193.3 99.0 85.2 56.7 130.8 97.5 145.9 8.4 205.1 53.0 113.3 7.1 16.0 97.0 257.5 143.0 122.1 100.1 383.0 880.0 182.6 21.4 78.9 88.4 119.7 73.3 51.3 121.6 90.8 580.9 118.6 624.2 350.0 218.1 ECHDC3 FLJ20909 ENSG00000134463 "Enoyl-CoA hydratase domain containing 3" Q96DC8 10 11742366-11764070 "Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.6;skeletal muscle: 128.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 81.2;Distal tubular cells: 144.8;Hepatocytes: 152.0;Proximal tubular cells: 209.9" "Cancer enhanced" "Detected in all" "liver cancer: 35.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 15.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "A-431: 52.9;BEWO: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA038306 Enhanced NA NA 120000 "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038306: AB_10672586" "unprognostic (8.74e-2)" "unprognostic (1.69e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (2.37e-2)" "unprognostic (1.09e-1)" "unprognostic (1.64e-1)" "unprognostic (5.07e-1)" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (3.53e-1)" "prognostic favorable (3.43e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (3.91e-4)" 71.7 29.3 2.6 3.2 2.4 7.0 52.8 2.5 2.5 15.9 17.5 6.7 1.8 11.0 2.2 22.9 11.1 1.8 67.0 2.6 4.3 63.0 161.6 17.5 3.7 3.0 2.7 10.5 29.7 1.8 10.8 7.9 2.9 13.7 3.6 2.0 28.6 13.7 128.4 21.7 6.0 4.4 2.9 15.7 26.6 14.3 3.8 2.8 17.9 60.1 5.5 9.3 17.8 3.3 52.9 7.6 0.1 0.0 0.0 0.0 28.7 6.3 0.0 4.6 4.0 19.1 0.4 0.0 5.8 14.1 1.3 12.5 11.9 1.9 2.0 0.1 0.5 0.0 7.6 0.0 20.5 0.0 7.4 14.1 11.8 4.8 0.0 0.4 9.3 0.0 19.6 0.0 1.4 7.3 0.0 0.2 13.3 0.1 0.0 16.3 0.0 0.0 3.6 0.0 5.5 8.4 0.0 13.1 0.0 16.5 20.5 2.6 2.8 0.0 5.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 3.6 2.9 1.7 15.4 0.0 0.6 0.0 0.2 0.1 0.5 1.7 1.7 0.3 0.0 3.6 0.5 0.7 0.6 0.0 0.3 2.6 2.4 2.5 2.5 2.6 4.3 3.0 2.7 2.9 2.9 3.8 3.3 2.7 19.2 11.8 0.0 3.6 4.5 13.8 2.7 0.0 0.9 16.7 27.2 42.2 17.2 6.4 16.5 2.1 81.2 0.1 1.3 144.8 33.6 4.0 2.3 5.9 3.5 0.0 1.7 0.3 29.8 32.9 6.0 16.3 4.6 0.0 49.5 4.6 152.0 13.1 0.0 0.2 0.6 6.1 14.1 2.2 6.3 2.8 10.6 8.8 1.0 6.8 13.1 0.0 0.0 0.5 13.6 1.2 3.4 6.4 26.1 0.9 209.9 0.4 2.7 19.7 12.0 12.0 22.1 9.6 0.4 5.7 28.9 1.5 4.9 1.9 6.8 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 EIF4EBP2 ENSG00000148730 "Eukaryotic translation initiation factor 4E binding protein 2" Q13542 10 70404145-70428618 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019415, HPA037410, HPA061665" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "CAB019415: AB_10699019, HPA037410: AB_2675461, HPA061665: AB_2684580" "unprognostic (9.57e-2)" "unprognostic (3.22e-2)" "unprognostic (2.27e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-1)" "unprognostic (3.51e-1)" "unprognostic (3.84e-1)" "unprognostic (7.24e-2)" "unprognostic (8.24e-2)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (1.46e-1)" "prognostic favorable (6.69e-6)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (1.53e-1)" "unprognostic (4.61e-2)" 67.7 27.6 27.8 23.2 25.2 30.4 44.8 21.8 23.6 29.0 28.9 41.2 40.4 25.1 16.5 31.9 25.8 23.8 40.8 21.0 23.9 57.3 50.5 30.5 26.2 28.9 26.6 34.9 30.2 27.5 11.2 43.8 21.7 24.7 39.6 34.9 28.2 33.6 64.2 35.0 47.3 27.2 23.6 26.7 30.9 18.2 34.7 34.5 23.2 67.4 29.2 36.2 28.2 20.1 56.3 17.8 93.7 92.0 176.9 66.8 51.8 33.5 40.5 24.0 25.9 77.5 48.1 57.2 20.1 48.6 14.9 35.6 46.2 30.4 26.9 63.6 24.0 41.4 21.1 30.8 41.5 74.4 28.4 74.8 30.8 29.4 26.4 48.4 36.8 46.0 69.0 50.7 37.5 31.5 64.3 76.3 80.7 54.2 31.8 66.3 37.6 37.4 30.7 56.3 51.1 77.6 45.7 103.0 44.5 63.8 47.2 65.3 40.6 15.6 20.0 25.8 30.2 35.5 73.2 66.5 18.1 108.2 16.3 20.8 19.2 28.7 16.4 16.8 13.2 9.0 13.1 13.8 17.2 8.2 10.9 11.4 21.1 11.6 23.0 5.7 15.7 19.2 27.8 25.2 21.8 23.6 21.0 23.9 28.9 26.6 21.7 23.6 34.7 20.1 72.5 25.6 37.6 21.9 31.9 52.9 53.5 25.4 27.9 46.8 42.9 32.5 147.0 68.6 29.1 36.8 20.9 47.3 45.2 196.7 43.0 43.9 25.9 33.1 52.1 41.4 26.5 70.5 13.0 59.3 119.1 49.9 34.7 57.8 11.4 39.0 61.8 157.4 46.0 23.5 17.5 73.6 34.6 95.4 45.1 59.0 65.9 50.9 21.4 24.4 92.9 73.1 76.2 22.1 9.1 59.5 94.7 61.3 33.8 63.4 195.2 137.0 23.4 17.2 78.9 46.4 37.1 43.7 47.1 39.1 70.0 57.3 43.0 47.0 73.1 109.4 ELMO1 "CED-12, CED12, ELMO-1, KIAA0281" ENSG00000155849 "Engulfment and cell motility 1" Q92556 7 36852906-37449223 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 228.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 236.7;Microglial cells: 519.0;Oligodendrocyte precursor cells: 284.0;Oligodendrocytes: 1412.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 129.9;JURKAT: 122.0;Karpas-707: 118.0;U-698: 141.7;U-937: 123.4" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.77e-2)" "unprognostic (8.29e-3)" "unprognostic (1.55e-1)" "unprognostic (1.19e-2)" "unprognostic (3.69e-1)" "unprognostic (4.09e-2)" "unprognostic (3.01e-2)" "unprognostic (3.53e-3)" "unprognostic (1.34e-1)" "unprognostic (1.71e-1)" "prognostic favorable (4.62e-4)" "unprognostic (3.59e-1)" "prognostic unfavorable (3.27e-5)" "unprognostic (1.65e-2)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (3.16e-3)" 27.5 14.5 77.5 32.4 131.5 59.4 21.9 95.1 108.2 14.9 24.3 11.8 6.6 7.8 4.5 10.9 10.4 21.2 16.6 82.9 88.5 6.9 28.0 28.9 49.2 131.7 108.9 13.4 13.2 4.9 12.0 38.1 124.2 10.8 13.0 12.9 9.4 9.9 7.2 10.1 19.1 15.9 89.5 56.4 9.0 6.5 126.1 29.4 82.0 16.6 51.4 18.7 15.5 228.3 0.2 4.1 7.6 0.0 0.0 0.0 16.4 0.2 0.1 0.0 0.0 0.2 0.0 129.9 2.2 0.0 1.0 0.5 0.0 0.0 0.0 72.7 4.7 94.6 0.3 0.0 0.0 60.5 38.0 1.6 0.0 0.0 0.0 0.0 49.8 122.0 1.5 118.0 0.0 0.8 69.8 84.0 19.4 0.2 0.0 77.5 10.1 72.3 0.2 0.0 8.5 40.3 0.3 24.1 0.5 27.3 0.1 43.3 14.4 0.2 1.4 0.3 0.6 98.8 90.1 141.7 21.1 123.4 6.0 49.9 52.8 164.1 33.2 45.7 33.8 49.8 52.1 36.6 78.2 39.7 47.1 36.3 107.0 41.6 40.6 40.1 47.8 55.6 77.5 131.5 95.1 108.2 82.9 88.5 131.7 108.9 124.2 89.5 126.1 228.3 60.4 0.0 4.8 10.4 53.3 5.0 4.5 0.0 3.4 13.7 2.0 2.8 3.5 7.2 0.6 0.0 0.0 1.5 26.8 0.4 0.0 0.2 1.0 1.8 2.4 44.6 3.6 24.6 236.7 1.1 26.7 14.6 0.0 1.1 34.9 6.9 37.1 15.4 20.4 0.0 106.7 0.9 0.0 50.7 58.3 1.5 6.2 44.8 7.2 519.0 34.6 1.1 41.2 284.0 1412.3 0.6 0.8 24.8 31.7 1.9 0.0 2.0 0.0 1.8 13.1 9.5 2.7 1.4 4.6 0.8 4.3 19.7 35.6 15.2 0.2 1.8 ELMOD3 "DFNB88, FLJ21977, RBED1, RBM29" ENSG00000115459 "ELMO domain containing 3" Q96FG2 2 85354394-85391752 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012126 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA012126: AB_1848130" "unprognostic (1.90e-1)" "unprognostic (9.80e-3)" "unprognostic (1.42e-3)" "unprognostic (1.76e-1)" "unprognostic (3.24e-1)" "unprognostic (1.60e-2)" "unprognostic (1.35e-2)" "unprognostic (1.52e-2)" "unprognostic (4.62e-2)" "unprognostic (5.63e-2)" "prognostic favorable (6.16e-6)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.09e-6)" "unprognostic (5.71e-2)" "unprognostic (1.53e-1)" "unprognostic (9.51e-2)" "prognostic favorable (2.85e-5)" 11.1 8.2 7.0 3.7 7.4 2.7 8.7 6.6 8.0 7.2 5.1 7.6 4.9 5.6 5.9 5.0 6.9 6.1 5.3 5.9 6.4 6.0 8.8 4.9 5.4 6.9 6.8 6.5 6.0 8.9 6.6 6.1 6.2 8.4 4.9 3.1 6.2 7.0 12.1 5.1 5.6 6.7 6.4 6.6 7.1 2.7 6.7 5.4 6.3 10.2 5.0 7.3 6.3 7.0 4.9 6.0 6.7 10.0 20.9 9.2 4.0 8.6 6.7 12.6 11.7 5.0 2.4 3.7 6.7 7.2 15.9 5.1 9.7 11.9 11.4 13.0 6.7 6.5 3.4 3.7 10.9 4.9 8.2 9.6 10.6 12.1 13.6 10.6 9.1 7.4 6.6 4.2 11.9 3.9 7.2 2.9 3.3 9.8 6.4 5.2 13.9 3.5 5.8 3.0 6.3 3.3 5.3 7.3 7.9 7.6 4.0 3.5 4.8 9.1 4.9 7.9 8.0 5.0 9.9 4.9 9.1 5.7 9.4 6.5 2.7 8.0 5.0 1.9 2.7 3.1 3.2 2.0 3.2 2.6 2.7 4.8 2.5 5.0 4.5 0.9 5.5 2.8 7.0 7.4 6.6 8.0 5.9 6.4 6.9 6.8 6.2 6.4 6.7 7.0 9.0 6.4 8.4 36.9 15.7 4.7 10.0 13.0 8.6 27.2 10.7 7.6 5.2 10.0 16.7 11.0 29.2 15.2 9.8 17.3 7.9 8.6 5.6 4.6 6.9 9.5 8.4 7.4 24.3 9.1 5.9 10.0 12.8 4.0 8.9 20.7 12.5 7.5 8.6 30.3 21.4 11.4 14.2 10.0 9.3 5.6 19.3 9.5 17.8 18.7 16.5 14.1 28.8 28.6 49.7 10.4 15.3 23.7 7.7 10.8 24.9 7.1 11.7 30.9 19.7 10.0 8.0 19.7 10.9 6.7 6.5 12.4 14.0 18.3 12.7 9.4 ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226299-102229589 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 30.5" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Breast myoepithelial cells: 3.2;Skeletal myocytes: 5.0;Spermatogonia: 3.4;Theca cells: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "classical monocyte: 7.1;intermediate monocyte: 2.4;myeloid DC: 2.0;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 10 "dendritic cells: 2.0;monocytes: 7.1" "Cell line enhanced" "Detected in many" "ASC diff: 9.5;ASC TERT1: 9.4;HSkMC: 13.9;NB-4: 11.6;SiHa: 22.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA036236 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" 3.2 0.7 1.0 0.3 0.8 1.8 3.5 0.5 1.3 0.1 0.3 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.2 1.0 0.4 0.8 0.0 1.0 0.1 0.4 0.9 0.1 0.0 0.1 0.0 0.9 0.4 0.2 0.1 0.1 0.3 0.1 0.2 30.5 0.2 0.0 0.4 0.8 0.1 1.2 0.4 0.0 0.0 0.3 0.0 0.2 0.3 0.5 3.2 0.2 0.2 7.8 9.5 9.4 2.8 0.1 0.3 0.4 0.5 0.5 3.0 0.0 0.3 0.0 0.0 0.1 5.9 0.1 0.5 0.0 0.0 0.2 0.4 0.8 0.3 0.0 0.1 13.9 1.6 3.6 0.0 0.0 0.0 0.9 0.1 3.5 0.8 0.0 0.0 11.6 0.1 1.1 1.0 0.0 5.1 0.0 2.0 0.1 0.0 0.4 22.6 0.9 0.7 0.6 8.1 2.7 0.0 1.5 0.0 0.3 0.3 0.5 7.2 0.0 3.4 6.5 0.0 0.0 7.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 5.9 0.0 0.0 1.7 1.0 0.8 0.5 1.3 1.0 0.4 0.4 0.9 0.4 0.4 0.4 0.5 2.5 0.0 1.1 0.0 0.2 0.4 0.5 0.6 0.6 0.0 1.1 3.2 0.3 0.0 0.5 0.0 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 1.3 1.9 0.0 0.0 0.3 0.0 0.7 1.3 0.0 0.2 0.0 0.0 1.4 0.4 0.2 0.0 0.0 0.2 0.0 1.5 0.8 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 5.0 1.2 0.1 3.4 0.6 0.1 0.3 0.3 2.2 0.2 0.1 ENPP4 "AP3Aase, KIAA0879, NPP4" ENSG00000001561 "Ectonucleotide pyrophosphatase/phosphodiesterase 4" Q9Y6X5 6 46129989-46146688 "Enzymes, Predicted membrane proteins" "Blood coagulation, Hemostasis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Oligodendrocytes: 125.3;Respiratory ciliated cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 21.9;U-266/84: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016594 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA016594: AB_1848171" "unprognostic (9.87e-2)" "unprognostic (1.74e-1)" "unprognostic (2.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.92e-1)" "unprognostic (1.90e-1)" "unprognostic (8.13e-2)" "unprognostic (5.51e-3)" "unprognostic (1.98e-1)" "unprognostic (1.26e-1)" "unprognostic (8.51e-2)" "unprognostic (4.36e-1)" "prognostic favorable (6.95e-7)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-2)" "unprognostic (2.56e-1)" 15.1 13.6 11.7 7.3 20.9 38.0 7.8 19.5 19.5 10.3 6.4 12.1 10.9 4.0 11.6 5.1 10.8 8.0 15.1 10.8 16.0 18.4 8.2 20.7 7.7 20.5 19.3 2.1 11.9 22.3 9.0 3.5 19.9 16.4 12.8 12.2 21.3 19.7 22.1 2.3 10.1 7.0 18.5 13.9 14.8 8.3 17.5 8.5 12.5 25.3 6.5 6.8 2.1 30.2 0.1 1.1 0.7 1.5 0.0 0.0 0.1 1.7 1.6 4.0 0.3 1.9 13.4 15.2 12.7 2.1 9.9 0.2 4.1 0.6 0.8 18.5 11.1 8.5 0.0 0.0 0.5 10.5 14.9 2.1 0.0 0.1 0.0 1.1 1.4 10.5 0.0 0.0 1.5 1.8 7.8 1.0 2.7 16.9 0.5 5.9 2.7 5.7 8.3 1.7 18.0 0.0 0.0 2.8 0.0 4.1 7.6 4.3 0.0 0.0 6.7 0.3 11.2 21.9 26.6 5.2 10.3 0.0 1.4 0.0 0.4 0.9 9.2 1.1 5.4 2.8 3.4 6.8 1.5 1.2 3.2 5.8 0.3 4.4 2.6 1.6 1.2 3.0 11.7 20.9 19.5 19.5 10.8 16.0 20.5 19.3 19.9 18.5 17.5 30.2 43.5 76.9 27.0 23.5 11.6 0.9 3.2 2.3 0.6 9.3 11.0 2.4 23.1 14.3 25.4 29.5 14.6 0.5 23.5 27.2 0.0 12.9 18.3 28.8 2.0 16.0 15.7 3.0 26.4 12.2 0.3 8.5 10.7 17.3 15.8 4.5 6.1 8.6 5.8 26.9 19.2 13.8 4.1 24.8 11.0 26.0 1.2 19.0 3.6 6.5 15.2 21.6 34.0 32.2 125.3 9.7 16.1 11.3 10.3 12.6 16.3 12.6 70.6 6.2 0.0 22.1 5.4 9.1 9.8 0.3 0.6 0.3 14.7 3.7 11.3 14.8 EPB42 "MGC116735, MGC116737, PA" ENSG00000166947 "Erythrocyte membrane protein band 4.2" P16452 15 43197227-43221018 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape, Erythrocyte maturation" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 98.9" "Cell type enriched" "Detected in many" 33 "Erythroid cells: 480.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 91 "HEL: 85.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040261 Supported Uncertain Nucleoplasm,Cytosol NA NA 1400000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "HPA040261: AB_10673441" "unprognostic (8.45e-2)" "unprognostic (4.66e-1)" "unprognostic (4.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.99e-1)" "unprognostic (1.54e-1)" "unprognostic (1.59e-3)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" "unprognostic (5.27e-3)" "unprognostic (1.31e-1)" "unprognostic (1.48e-5)" "unprognostic (1.70e-2)" "unprognostic (1.20e-1)" "unprognostic (5.88e-2)" "unprognostic (3.47e-3)" 3.1 0.0 0.0 0.0 0.0 98.9 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 2.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 1.9 1.5 0.5 0.0 4.0 0.0 0.0 0.6 1.5 0.5 0.0 6.2 4.5 0.0 1.5 0.0 0.0 14.4 0.0 0.0 1.2 0.0 480.0 0.1 0.0 2.3 0.8 0.0 0.0 4.5 0.0 2.5 1.1 1.1 6.7 0.1 0.9 4.1 2.2 2.8 10.5 2.8 1.1 1.8 0.0 3.6 2.5 14.4 0.0 0.0 0.0 1.7 0.7 0.4 1.5 2.4 0.0 0.6 8.4 6.6 1.0 1.0 13.5 4.6 0.0 2.8 6.7 3.8 0.0 0.8 2.0 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ESYT1 "FAM62A, KIAA0747, MBC2" ENSG00000139641 "Extended synaptotagmin 1" Q9BSJ8 12 56118250-56144674 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016858, HPA076926" Approved Supported "Endoplasmic reticulum" NA NA 720000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA016858: AB_1848404, HPA076926: AB_2686819" "unprognostic (5.02e-2)" "unprognostic (3.62e-2)" "unprognostic (6.26e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (8.44e-2)" "unprognostic (5.41e-2)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (1.77e-1)" "unprognostic (6.85e-3)" "unprognostic (1.29e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.04e-2)" "unprognostic (8.43e-3)" "unprognostic (1.52e-2)" "unprognostic (3.98e-2)" 107.9 39.3 15.2 38.5 14.4 18.7 72.7 18.5 18.9 36.6 19.8 45.9 17.2 53.4 22.2 29.2 47.1 27.8 24.5 13.5 23.0 26.8 46.7 45.0 45.9 34.2 21.7 38.8 39.5 40.7 11.7 38.7 36.2 30.5 36.2 8.9 28.0 47.2 54.2 26.1 30.7 74.4 22.5 37.2 29.3 12.1 23.6 36.6 27.8 33.3 49.8 44.7 32.3 24.0 107.0 78.1 62.2 158.2 90.8 67.3 53.4 117.4 129.3 136.2 94.4 72.4 114.3 40.8 92.2 201.3 50.7 118.7 73.7 120.4 121.6 58.8 54.2 244.7 56.0 58.5 125.9 193.2 371.6 76.7 125.5 147.1 81.3 145.3 117.8 39.2 153.6 263.9 124.4 81.2 70.4 116.4 78.9 44.6 102.5 105.4 85.0 107.3 113.7 89.0 52.4 54.8 174.1 52.9 80.5 71.3 111.1 128.4 154.5 104.8 94.7 59.7 85.7 62.3 99.0 58.7 97.3 79.6 111.7 423.2 37.4 423.0 127.2 69.4 157.2 62.4 129.4 129.5 87.2 48.2 102.3 120.2 9.3 84.2 85.6 29.7 139.6 177.8 15.2 14.4 18.5 18.9 13.5 23.0 34.2 21.7 36.2 22.5 23.6 24.0 44.4 9.6 9.3 4.6 25.9 16.3 19.8 23.5 14.2 5.5 20.5 21.3 8.2 14.3 12.9 31.3 10.4 31.9 22.3 6.1 0.0 36.8 2.0 20.5 15.1 28.2 25.2 17.9 10.2 26.8 18.1 17.6 9.2 19.3 62.7 24.7 27.1 37.8 46.4 0.0 7.1 12.0 22.4 21.3 24.8 2.1 17.4 22.9 35.6 6.5 50.6 5.7 60.8 2.0 4.1 26.2 3.5 25.2 18.5 19.9 2.2 4.4 10.7 5.9 52.6 14.3 22.0 3.9 2.9 18.0 11.9 37.9 40.3 12.5 10.8 12.7 ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76215353-76311472 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 389.7;tongue: 493.5" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 402.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 680000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018990: AB_1848277, HPA018993: AB_1848275, HPA018996: AB_1848276, HPA024089: AB_1848278" "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (3.71e-3)" "unprognostic (5.99e-2)" "unprognostic (6.81e-3)" "unprognostic (3.02e-1)" "unprognostic (5.01e-2)" "unprognostic (6.01e-2)" "unprognostic (3.38e-3)" "unprognostic (1.99e-1)" "prognostic favorable (5.04e-8)" "unprognostic (2.87e-1)" "unprognostic (4.90e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" 93.0 112.3 33.8 55.0 36.0 63.0 70.4 36.0 54.6 38.7 40.3 131.4 135.6 27.0 30.6 85.1 30.1 44.7 243.0 34.2 37.6 180.0 389.7 39.0 60.9 35.6 35.7 25.6 81.6 71.0 13.9 70.9 36.0 42.2 123.5 34.3 49.3 38.2 300.8 40.1 116.3 65.7 35.5 38.8 67.7 28.4 38.2 54.5 38.7 493.5 65.9 74.0 33.1 36.9 122.4 196.7 128.2 134.8 141.7 149.1 201.0 144.4 166.2 183.0 162.8 175.3 221.3 203.5 141.3 144.3 138.5 304.6 502.7 200.2 211.9 245.8 98.0 222.2 131.4 205.2 114.7 214.5 158.7 112.7 185.9 93.1 153.5 100.0 187.8 64.7 214.1 205.2 190.3 191.2 44.9 178.2 99.9 225.3 58.4 192.8 158.6 272.8 202.1 386.9 133.3 67.2 218.2 492.2 205.0 294.4 254.1 223.4 111.4 178.2 119.5 157.0 177.4 99.0 221.0 255.9 127.8 281.1 128.5 50.0 120.3 82.7 65.4 110.3 61.7 77.3 60.6 67.6 159.4 67.3 48.8 60.1 30.2 122.9 96.1 63.4 95.8 141.9 33.8 36.0 36.0 54.6 34.2 37.6 35.6 35.7 36.0 35.5 38.2 36.9 65.7 57.7 41.6 45.1 54.3 53.4 110.8 151.5 44.9 13.1 47.2 46.4 352.9 65.8 84.5 36.8 22.9 277.4 61.1 250.9 209.4 106.5 11.7 29.5 45.1 51.8 65.4 117.8 26.0 84.1 180.8 66.8 90.2 37.0 38.6 53.1 48.9 348.8 132.3 53.8 31.5 141.6 89.5 79.0 84.5 7.9 59.4 103.0 56.9 28.1 129.0 26.7 85.5 37.2 46.9 92.1 176.2 58.3 87.8 92.4 231.1 402.9 50.2 20.4 46.0 44.0 113.7 66.4 40.5 79.5 57.1 300.2 55.5 123.4 187.3 162.0 ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 493.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1105.3;Proximal enterocytes: 710.7;Proximal tubular cells: 1118.7" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1693.9;OE19: 770.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" 159.1 171.5 121.1 44.0 134.4 70.2 115.3 134.8 145.5 55.7 123.0 97.6 136.3 48.9 16.9 140.7 53.3 62.7 387.8 112.8 120.6 144.5 493.6 50.4 58.2 129.8 124.8 55.2 81.9 106.3 73.1 39.0 125.7 55.2 41.2 24.1 172.2 37.9 280.7 79.0 129.7 31.7 119.9 64.5 90.0 53.6 132.4 81.4 70.3 280.3 36.9 65.6 69.0 137.0 118.9 304.3 41.3 113.9 129.4 150.4 65.6 82.4 61.0 63.5 63.1 257.3 192.1 121.5 80.2 129.8 33.8 104.0 83.3 171.1 19.2 182.0 323.3 98.1 188.9 1693.9 141.8 92.1 67.6 235.3 50.3 86.1 88.2 79.2 54.9 115.0 146.6 130.2 83.2 243.7 95.2 86.2 26.7 770.2 372.0 104.5 114.4 224.6 88.5 135.7 91.7 44.5 184.5 49.9 94.4 29.4 130.3 86.3 77.8 65.9 67.6 71.4 73.3 195.8 130.0 109.8 335.0 135.1 172.5 127.7 190.1 119.6 104.3 212.3 137.4 281.6 156.0 134.2 225.3 303.1 163.6 136.0 97.8 205.3 165.7 265.1 225.7 140.5 121.1 134.4 134.8 145.5 112.8 120.6 129.8 124.8 125.7 119.9 132.4 137.0 90.9 80.1 93.8 15.3 75.6 65.0 114.9 196.4 55.2 77.1 129.9 170.1 243.8 234.4 122.5 121.4 31.3 240.7 58.7 440.9 571.3 188.0 139.2 67.5 70.2 76.2 168.4 120.0 4.1 140.5 206.6 93.8 128.9 48.2 88.8 63.2 144.9 1105.3 217.5 43.7 4.2 335.2 158.7 147.7 73.4 354.4 107.5 86.9 286.4 5.6 95.2 158.8 50.4 7.1 18.9 155.4 339.4 114.3 69.9 74.9 710.7 1118.7 118.8 67.9 98.6 87.4 144.5 71.0 52.8 135.3 63.6 160.1 74.0 217.3 354.4 140.3 ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158672125-158709623 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease variant, FDA approved drug targets, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.4;tongue: 186.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 146.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041978 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041978: AB_10795605" "unprognostic (7.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.90e-2)" "unprognostic (5.92e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "prognostic favorable (5.76e-10)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-3)" "unprognostic (1.74e-1)" 34.6 38.0 13.3 10.7 14.8 9.4 16.0 13.9 15.1 10.2 25.5 32.6 63.7 10.4 8.4 25.0 9.3 11.1 93.3 12.8 14.5 46.5 196.4 9.2 8.7 12.3 13.8 10.8 20.4 32.8 9.8 13.0 12.8 13.7 26.9 15.8 21.8 13.2 111.0 18.7 51.4 14.8 12.5 9.5 26.9 11.2 15.0 9.4 13.2 186.9 14.3 12.9 12.8 15.1 13.2 9.2 12.2 21.4 47.2 28.8 6.6 21.3 19.4 13.9 14.3 3.7 24.6 27.8 4.6 24.1 15.8 13.8 22.1 20.9 19.2 51.5 20.3 26.5 17.3 8.0 20.8 24.0 23.4 26.5 23.8 15.8 12.8 20.8 27.3 20.7 15.6 53.8 22.2 14.7 22.7 11.0 5.0 33.2 19.4 18.4 4.3 21.9 21.2 10.6 18.7 8.0 21.0 39.5 21.8 10.0 30.4 17.6 13.6 11.9 6.7 18.5 12.2 31.3 42.1 20.3 24.6 19.2 13.5 3.7 21.5 41.5 10.1 22.6 12.7 10.3 9.8 10.4 18.3 9.6 11.6 9.9 7.8 10.5 20.9 13.1 16.1 9.5 13.3 14.8 13.9 15.1 12.8 14.5 12.3 13.8 12.8 12.5 15.0 15.1 18.1 12.8 10.3 55.2 18.5 33.0 46.0 27.2 29.6 29.2 12.6 13.8 146.6 14.3 22.8 18.4 64.6 24.9 18.0 34.4 29.4 14.4 4.2 12.5 12.5 17.7 18.0 30.7 43.2 11.7 9.9 23.9 44.4 14.2 5.1 19.2 12.8 85.7 13.4 25.2 71.9 22.5 30.5 14.4 15.8 4.7 23.0 13.3 8.8 15.0 12.2 13.9 10.3 55.8 58.0 11.7 29.4 23.7 30.1 21.3 58.3 26.8 13.1 43.9 32.9 27.4 30.4 43.2 29.8 32.7 36.9 43.0 19.7 15.7 26.2 38.7 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 FAH ENSG00000103876 "Fumarylacetoacetate hydrolase" P16930 15 80152490-80186946 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 301.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 266.8;Proximal tubular cells: 305.5" "Cancer enhanced" "Detected in all" "liver cancer: 23.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041370, HPA044093" Enhanced Approved Nucleoplasm,Cytosol NA NA 220000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA041370: AB_2677438, HPA044093: AB_2678806" "unprognostic (3.15e-1)" "unprognostic (5.65e-2)" "unprognostic (1.64e-1)" "unprognostic (6.16e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.19e-2)" "unprognostic (5.83e-2)" "unprognostic (2.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.17e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "unprognostic (2.93e-1)" "unprognostic (8.98e-2)" 99.2 65.4 16.0 7.0 17.1 20.0 59.0 16.6 21.1 19.2 15.1 13.8 14.6 19.3 50.4 15.2 23.0 9.7 20.3 16.3 18.8 65.0 301.5 20.0 5.7 17.9 19.6 26.4 9.9 18.4 16.8 7.8 16.9 16.6 11.9 1.6 14.8 13.6 31.0 10.9 16.8 13.5 17.2 19.1 14.2 20.8 17.4 6.7 14.5 27.7 5.8 16.4 15.8 17.5 20.1 34.4 13.5 17.0 60.2 62.2 32.9 24.3 56.8 26.2 22.3 22.0 35.9 0.4 39.0 52.6 36.8 29.1 46.8 59.6 25.1 12.5 28.5 166.6 18.0 112.1 316.6 79.6 88.8 107.5 37.1 22.9 39.7 84.2 37.4 38.3 71.1 35.7 50.3 31.0 22.3 42.0 9.9 15.5 37.6 12.2 19.3 123.4 77.0 25.2 0.7 8.3 27.4 76.7 77.9 21.6 58.3 55.0 126.1 46.8 30.0 25.5 42.7 32.7 69.5 13.8 99.6 187.5 26.9 34.5 18.8 3.3 9.6 8.1 2.3 0.1 2.4 6.0 25.3 0.1 3.1 2.7 1.3 5.7 8.4 1.9 2.5 9.7 16.0 17.1 16.6 21.1 16.3 18.8 17.9 19.6 16.9 17.2 17.4 17.5 3.0 3.2 13.8 9.8 4.1 6.8 17.5 30.8 15.4 0.4 19.1 13.7 15.5 21.5 12.5 33.1 0.0 37.9 4.9 9.3 52.8 9.3 7.5 3.0 16.2 3.2 4.2 24.4 0.4 3.5 14.1 16.6 3.6 4.0 41.9 6.3 8.9 266.8 72.5 0.0 2.5 13.0 24.4 21.4 6.6 13.5 9.9 30.5 19.6 1.0 5.7 7.3 3.1 2.5 0.6 4.5 12.8 7.9 5.2 9.7 54.1 305.5 5.3 0.4 0.0 9.2 11.2 1.5 2.1 18.2 5.7 22.0 7.7 8.7 22.4 16.4 FAM166B ENSG00000215187 "Family with sequence similarity 166 member B" A8MTA8 9 35561831-35563899 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "adrenal gland: 270.0;fallopian tube: 83.1;skeletal muscle: 185.9" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 108.0;Respiratory ciliated cells: 126.4" "Group enriched" "Detected in many" 5 "endometrial cancer: 11.7;ovarian cancer: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045540 Enhanced NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA045540: AB_10962627" "unprognostic (4.18e-5)" "unprognostic (7.56e-3)" "unprognostic (1.65e-1)" "prognostic favorable (2.61e-5)" "unprognostic (5.66e-3)" "unprognostic (3.48e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-2)" "unprognostic (2.21e-1)" "prognostic favorable (6.20e-6)" "unprognostic (3.69e-3)" "unprognostic (9.09e-2)" "unprognostic (4.37e-3)" "unprognostic (5.82e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (3.52e-5)" 5.2 270.0 1.9 0.0 1.5 0.0 2.5 1.2 1.2 3.6 8.8 0.3 0.0 1.3 9.0 0.6 83.1 0.1 0.5 1.7 2.3 0.7 0.6 4.2 0.1 4.7 7.0 0.3 0.2 0.1 0.4 0.0 4.5 0.3 0.2 0.1 0.7 0.6 185.9 0.6 0.6 0.1 5.5 0.2 0.4 0.2 2.2 0.0 0.3 18.3 0.3 0.2 0.2 2.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.5 1.2 1.2 1.7 2.3 4.7 7.0 4.5 5.5 2.2 2.7 0.3 0.0 0.5 0.0 0.0 4.7 1.2 9.2 2.2 0.0 0.3 2.4 0.3 0.0 10.1 0.0 2.1 0.2 0.3 0.0 0.0 0.2 0.3 108.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.2 0.0 0.1 0.4 0.5 0.1 0.0 0.1 0.0 24.4 0.0 0.7 0.3 0.3 0.3 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 3.3 126.4 0.2 0.0 3.1 3.3 0.2 0.2 2.0 2.0 0.0 0.3 2.1 0.2 0.5 FAM234A "C16orf9, DKFZP761D0211, FLJ32603, ITFG3" ENSG00000167930 "Family with sequence similarity 234 member A" Q9H0X4 16 234521-272183 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011651, HPA071871" Uncertain Uncertain Nucleoplasm,Mitochondria NA NA 5300000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA011651: , HPA071871: AB_2732188" "unprognostic (1.00e-1)" "unprognostic (1.85e-2)" "unprognostic (3.49e-1)" "unprognostic (4.80e-2)" "unprognostic (5.51e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.93e-1)" "unprognostic (2.21e-2)" "unprognostic (7.52e-2)" "unprognostic (1.16e-1)" "unprognostic (3.28e-2)" "unprognostic (2.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (3.68e-1)" 59.5 57.9 22.5 25.1 38.7 19.9 46.5 41.1 30.5 38.3 41.3 71.2 101.2 52.5 21.5 59.7 40.8 37.6 116.8 21.9 25.7 57.7 51.5 36.6 19.2 59.0 37.2 39.5 68.4 48.2 58.1 38.6 54.8 52.5 30.1 9.8 41.2 39.4 175.7 49.1 64.7 40.6 35.7 30.2 59.8 45.1 37.1 16.7 50.5 77.0 15.0 60.1 38.3 71.1 29.5 67.1 72.3 152.1 110.2 66.3 39.2 71.5 92.7 41.9 54.2 67.6 76.9 30.2 104.2 90.8 37.3 55.2 27.6 48.4 35.7 40.5 48.5 35.7 38.8 53.2 81.0 21.4 22.5 74.4 58.7 67.1 48.1 119.8 74.1 39.1 42.1 6.0 44.9 140.0 22.1 25.2 89.1 44.2 31.1 66.5 48.0 120.5 73.9 29.6 83.1 73.9 107.9 58.3 61.5 63.3 81.5 31.4 63.3 76.7 25.2 43.8 21.3 15.6 7.1 37.6 54.4 30.1 104.9 11.7 17.7 13.3 10.1 17.7 5.2 7.1 8.9 10.0 18.0 9.5 10.0 11.3 6.1 15.8 17.2 6.5 9.4 13.9 22.5 38.7 41.1 30.5 21.9 25.7 59.0 37.2 54.8 35.7 37.1 71.1 20.2 9.6 12.6 0.0 7.4 0.0 11.3 0.0 9.6 8.9 23.9 19.7 0.0 21.5 5.0 31.3 25.0 58.7 8.8 25.2 7.9 49.4 27.9 22.2 26.8 18.1 35.2 14.5 0.0 26.1 48.8 21.0 23.4 33.2 8.8 59.2 22.9 23.5 25.7 10.1 0.0 26.4 0.0 14.4 0.0 78.1 16.8 10.9 0.0 0.0 39.6 11.1 10.3 0.0 0.0 18.4 41.5 21.8 5.7 14.8 102.1 18.6 6.6 12.0 19.7 16.9 20.1 29.2 30.8 18.2 0.0 66.2 6.8 73.3 40.4 10.7 FAM240C ENSG00000216921 "Family with sequence similarity 240 member C" A0A1B0GVR7 2 241893988-241902551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "tongue: 225.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.5;REH: 2.4;SCLC-21H: 1.6" HPA073342 Approved Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" Nucleoplasm "HPA073342: " "unprognostic (9.31e-2)" "unprognostic (4.59e-2)" "unprognostic (1.61e-2)" "unprognostic (1.10e-1)" "unprognostic (7.48e-2)" "unprognostic (3.12e-1)" "unprognostic (2.93e-2)" "unprognostic (4.75e-2)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (2.04e-2)" "unprognostic (5.12e-2)" "unprognostic (5.44e-2)" "unprognostic (8.45e-2)" "unprognostic (2.44e-1)" "unprognostic (3.29e-1)" 3.5 0.7 5.9 0.1 6.9 0.3 3.9 6.4 8.2 1.4 5.6 0.2 0.2 1.9 0.0 4.0 1.7 0.1 1.3 5.4 5.9 0.1 0.2 0.1 0.4 6.2 6.4 1.6 36.8 0.5 0.4 0.2 6.4 3.5 0.0 0.6 5.4 3.9 10.2 3.1 0.2 0.1 5.6 0.3 0.4 1.3 6.3 3.4 6.9 225.1 0.2 0.4 1.0 5.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.2 0.0 0.7 0.5 0.0 0.2 0.0 0.0 2.4 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.9 6.4 8.2 5.4 5.9 6.2 6.4 6.4 5.6 6.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FAM89A "C1orf153, MGC15887" ENSG00000182118 "Family with sequence similarity 89 member A" Q96GI7 1 231018958-231040254 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.0;placenta: 68.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 186.3;Extravillous trophoblasts: 267.5;Rod photoreceptor cells: 102.5;Syncytiotrophoblasts: 278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 145.4;SK-MEL-30: 81.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059052, HPA059578" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles" Nucleoplasm "HPA059052: AB_2683890, HPA059578: AB_2684070" "unprognostic (7.80e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-3)" "unprognostic (1.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.10e-1)" "unprognostic (8.05e-3)" "unprognostic (4.85e-1)" "unprognostic (1.54e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.87e-2)" "unprognostic (2.03e-1)" "unprognostic (2.01e-1)" "unprognostic (9.26e-2)" 60.0 18.0 16.0 4.8 15.3 5.9 36.5 20.7 16.4 11.0 21.3 4.4 1.7 7.5 1.6 6.5 7.1 5.9 10.6 14.2 23.4 22.2 9.2 19.2 5.9 22.6 21.4 6.0 10.6 6.0 5.8 68.2 20.9 7.1 2.7 17.3 5.3 4.6 5.9 30.6 4.6 4.1 21.2 17.5 7.6 3.0 25.1 2.9 5.5 6.7 4.7 8.9 9.2 19.5 0.9 13.7 6.3 13.4 15.0 3.0 145.4 7.8 5.8 2.8 5.1 21.1 12.1 0.0 1.8 5.1 16.7 8.4 12.0 1.9 2.3 42.4 28.9 6.7 0.3 0.9 57.6 5.0 35.2 50.1 26.6 0.0 13.2 0.1 7.4 15.0 53.4 8.6 2.7 5.0 3.2 8.8 9.4 12.6 4.3 16.6 20.3 16.0 10.1 14.8 5.8 16.1 2.6 1.2 81.6 13.9 0.8 29.2 1.1 22.5 0.1 0.4 14.7 18.3 23.7 11.6 6.7 9.8 45.7 1.4 0.2 0.0 0.2 0.0 0.3 0.3 0.2 0.5 0.0 0.1 0.4 0.9 0.0 0.1 0.0 0.0 0.0 0.2 16.0 15.3 20.7 16.4 14.2 23.4 22.6 21.4 20.9 21.2 25.1 19.5 82.3 0.0 2.6 3.6 4.2 30.1 22.0 0.3 8.0 48.1 3.8 5.2 3.3 7.2 0.7 0.0 77.2 186.3 4.9 0.3 3.9 2.8 1.3 1.3 39.3 44.5 0.0 14.9 1.1 3.3 267.5 11.6 0.5 2.6 4.5 0.5 10.8 11.1 51.0 8.4 10.8 0.6 0.0 19.6 2.1 3.6 2.8 8.5 21.4 22.5 0.5 26.2 1.0 10.1 2.0 4.4 0.5 1.5 1.4 30.2 0.0 5.1 0.1 102.5 0.0 9.9 8.5 4.2 11.6 1.7 32.8 278.3 5.5 0.4 1.3 15.4 FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 14 "dendritic cells: 43.4;NK-cells: 79.3;T-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" 0.3 0.8 0.1 1.0 0.2 2.8 0.6 0.1 0.2 0.4 0.1 0.8 1.9 0.5 0.7 0.3 0.3 1.1 0.3 0.2 0.1 0.3 1.1 2.0 5.7 0.3 0.2 0.3 0.1 0.0 0.1 0.2 0.2 0.5 0.9 0.0 0.9 0.3 0.1 0.4 1.4 0.3 0.0 4.1 1.5 0.2 0.1 0.6 0.2 0.0 1.8 0.8 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 58.1 0.2 35.5 0.0 11.5 31.4 0.1 0.0 2.2 25.0 1.9 41.5 0.1 0.0 0.2 14.9 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.4 0.4 0.0 2.5 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 43.4 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.6 1.8 0.0 0.9 0.0 79.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 28.8 0.0 0.0 0.1 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBXO27 "Fbg5, Fbx27" ENSG00000161243 "F-box protein 27" Q8NI29 19 38990714-39032785 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 37.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Suprabasal keratinocytes: 17.8;Syncytiotrophoblasts: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 35.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA046800, HPA062242" Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA046800: AB_2679813, HPA062242: AB_2684723" "prognostic favorable (2.15e-4)" "unprognostic (7.32e-2)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (1.48e-3)" "unprognostic (4.38e-3)" "unprognostic (1.02e-1)" "unprognostic (8.95e-2)" "unprognostic (1.67e-1)" "unprognostic (7.31e-3)" "unprognostic (6.80e-2)" "unprognostic (9.31e-2)" "unprognostic (2.25e-2)" "unprognostic (8.72e-3)" "unprognostic (6.04e-2)" "unprognostic (7.51e-2)" "unprognostic (3.21e-2)" 13.3 3.7 17.5 2.1 15.9 2.7 6.2 23.8 18.7 6.3 6.4 6.8 2.2 4.7 2.4 15.4 5.3 5.5 19.6 15.4 8.9 6.4 7.5 3.2 3.7 10.7 6.7 10.2 4.8 2.5 4.1 3.8 9.1 8.9 8.7 4.9 7.4 7.8 1.6 37.5 4.9 7.4 4.9 3.1 3.8 4.7 11.1 4.0 4.6 2.4 4.0 7.7 9.7 13.1 9.1 11.4 0.3 7.2 15.3 0.8 3.3 1.2 6.7 5.2 4.9 3.8 3.4 0.9 17.5 10.3 9.0 15.5 0.6 6.6 3.4 0.8 0.4 0.3 3.0 0.6 2.7 0.9 2.5 5.5 10.2 5.4 0.4 8.2 3.3 0.4 5.4 1.2 7.2 8.1 0.6 1.4 8.1 3.0 20.4 0.2 0.1 1.1 3.4 35.3 0.4 10.8 17.7 2.2 0.1 4.8 9.2 1.7 4.0 0.5 0.4 0.3 0.9 3.5 8.9 1.9 9.0 0.2 0.3 1.1 0.3 0.2 0.3 0.3 0.2 0.4 0.2 0.2 0.2 0.6 0.4 0.3 1.7 1.7 0.2 0.5 0.3 0.2 17.5 15.9 23.8 18.7 15.4 8.9 10.7 6.7 9.1 4.9 11.1 13.1 0.2 3.2 15.0 2.3 0.1 5.9 4.1 1.4 9.1 7.5 3.8 4.2 9.5 7.2 6.4 1.8 0.0 36.1 0.5 0.2 1.9 1.5 3.7 1.9 3.6 3.2 0.0 0.0 4.8 0.8 4.8 2.7 6.1 1.6 7.6 2.3 1.4 3.2 4.9 8.4 4.6 0.2 8.2 0.3 4.9 2.5 2.8 2.1 0.0 1.0 1.1 5.6 0.0 3.0 4.1 0.3 0.0 4.1 1.9 2.3 6.9 7.3 4.7 3.0 0.0 1.8 1.5 6.4 2.0 13.5 17.8 27.0 1.3 0.4 0.2 5.3 FCER1G ENSG00000158869 "Fc fragment of IgE receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.6;lymphoid tissue: 470.1" "Group enriched" "Detected in many" 9 "dendritic cells: 726.6;granulocytes: 705.6;Hofbauer cells: 2318.6;Kupffer cells: 1950.8;Langerhans cells: 1526.3;Macrophages: 1971.3;monocytes: 808.9;NK-cells: 1037.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 1987.3;classical monocyte: 3240.2;intermediate monocyte: 5333.6;myeloid DC: 2386.3;neutrophil: 1831.0;NK-cell: 1750.9;non-classical monocyte: 6984.5;plasmacytoid DC: 3315.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "HEL: 77.8;HMC-1: 301.7;THP-1: 276.1;U-266/84: 90.1;U-937: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" 251.7 86.5 34.0 275.6 33.8 441.6 62.9 35.5 66.0 52.5 47.5 82.7 44.9 30.7 38.7 30.6 72.0 101.5 53.1 33.7 42.0 40.3 177.3 286.6 160.9 53.4 48.7 19.9 22.3 26.8 26.9 211.0 50.1 31.0 113.2 8.3 42.9 38.8 11.9 21.0 60.6 160.3 41.5 470.1 39.4 14.5 49.9 62.7 25.5 34.6 82.5 254.6 21.7 65.4 0.2 0.0 0.7 1.3 1.8 0.7 0.4 0.5 0.2 0.5 0.8 2.2 0.1 0.5 0.7 0.0 0.3 0.2 0.5 0.0 0.4 0.3 1.5 77.8 0.6 14.0 0.3 16.1 301.7 6.0 3.3 2.3 0.2 0.7 0.4 1.8 0.1 7.3 2.4 0.5 1.4 37.9 1.6 0.0 0.0 0.1 6.7 0.2 0.5 0.4 0.3 1.0 0.6 0.1 2.7 1.4 0.2 276.1 0.4 1.8 0.4 0.9 1.1 3.0 90.1 0.9 1.7 87.1 0.5 1987.3 3240.2 307.3 13.6 5333.6 15.9 28.2 10.6 10.6 2386.3 9.0 17.3 45.0 1831.0 1750.9 6984.5 3315.6 21.8 4265.5 34.0 33.8 35.5 66.0 33.7 42.0 53.4 48.7 50.1 41.5 49.9 65.4 12.8 86.6 147.7 0.7 35.9 39.6 1.5 0.2 1.8 0.1 5.2 22.1 6.8 15.7 27.3 18.4 0.0 14.5 726.6 1.0 0.0 1.9 3.0 1.0 0.9 38.6 1.8 79.3 0.1 1.0 18.8 18.3 1.1 1.0 705.6 0.5 41.0 13.6 2318.6 0.0 0.2 0.5 0.0 1950.8 1526.3 9.4 5.3 1971.3 80.0 12.2 808.9 0.2 1037.1 0.0 0.1 1.0 1.4 1.2 10.1 1.3 0.4 5.4 15.3 2.3 72.3 3.8 11.2 1.0 2.5 1.4 35.9 23.7 133.3 0.4 0.6 1.8 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 5 "B-cells: 102.6;Early spermatids: 63.6;Plasma cells: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 5 "U-266/70: 3.4;U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" 0.4 0.4 0.0 13.8 0.0 2.3 2.4 0.0 0.1 0.6 0.0 5.5 5.8 0.1 0.3 0.8 0.4 1.2 0.3 0.0 0.0 0.4 0.3 1.1 24.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 4.4 0.0 3.8 0.3 0.0 0.0 5.0 0.1 0.1 15.1 4.5 0.6 0.0 4.1 0.6 0.0 36.3 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 102.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.1 2.9 0.1 0.0 0.0 63.6 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.3 1.1 0.0 1.3 0.0 0.4 1.8 0.3 0.0 0.1 0.0 0.0 0.3 0.3 10.1 0.3 0.2 23.2 0.0 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 190.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.3 1.2 0.1 0.1 0.0 0.7 5.7 0.0 0.6 0.0 FERMT3 "KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2" ENSG00000149781 "Fermitin family member 3" Q86UX7 11 64206678-64223891 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.6;lymphoid tissue: 130.1" "Cell type enhanced" "Detected in many" "dendritic cells: 118.3;granulocytes: 96.4;Hofbauer cells: 193.1;Kupffer cells: 95.8;Langerhans cells: 88.0;Macrophages: 232.9;monocytes: 142.9;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 306.9;HL-60: 135.9;HMC-1: 314.2;Karpas-707: 127.6;MOLT-4: 121.8;NB-4: 174.1;U-937: 138.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065231 Approved Vesicles NA NA 160000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA065231: AB_2685439" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.38e-3)" "prognostic favorable (9.89e-4)" "unprognostic (8.77e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (2.46e-1)" "unprognostic (4.20e-1)" "unprognostic (3.98e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.12e-5)" "unprognostic (3.08e-3)" "unprognostic (5.25e-2)" "unprognostic (4.97e-2)" "unprognostic (1.75e-1)" 25.1 14.5 9.4 63.3 11.6 180.6 13.0 11.2 18.1 8.5 12.2 17.3 22.0 8.4 0.7 6.4 13.6 15.6 12.0 9.8 11.6 11.1 12.5 46.2 89.2 17.9 12.2 5.1 7.0 1.3 5.9 15.0 13.2 8.2 8.1 0.6 10.7 4.4 6.0 7.1 34.1 9.4 13.3 130.1 29.6 4.5 17.1 48.7 10.0 4.6 41.8 19.8 7.3 15.3 1.2 1.6 0.5 0.9 0.3 0.8 2.0 1.4 0.2 0.4 0.3 2.6 2.3 32.6 3.2 6.3 0.7 2.4 1.0 0.5 0.5 83.9 0.6 306.9 1.6 0.1 10.8 135.9 314.2 1.2 1.1 5.2 0.0 0.5 81.2 77.0 7.3 127.6 8.6 3.5 121.8 174.1 1.2 1.0 2.3 72.4 8.8 0.7 0.3 0.7 1.9 0.5 0.7 4.5 1.7 0.7 2.0 92.6 7.8 1.1 2.5 1.9 0.9 1.5 3.3 59.4 19.5 138.9 86.6 204.1 207.0 236.5 120.0 192.6 114.9 54.5 94.1 112.0 162.0 53.1 60.9 80.6 184.6 102.4 151.2 195.7 120.9 292.6 9.4 11.6 11.2 18.1 9.8 11.6 17.9 12.2 13.2 13.3 17.1 15.3 3.8 9.6 14.7 0.7 52.1 4.7 0.9 0.3 3.4 0.5 3.3 5.2 2.4 4.3 3.9 0.0 0.0 1.2 118.3 6.1 0.0 0.8 0.4 4.3 5.6 7.9 0.0 62.5 1.2 2.4 1.4 5.4 19.9 7.3 96.4 0.4 19.6 1.4 193.1 0.0 1.5 32.1 0.0 95.8 88.0 0.9 0.9 232.9 17.8 5.6 142.9 0.3 93.7 1.0 1.5 4.3 10.9 2.6 35.2 0.9 8.2 0.4 1.0 0.3 6.6 13.7 6.6 1.2 0.8 1.9 4.5 2.6 78.5 1.4 15.0 0.7 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.4;pituitary gland: 11.0" "Cell type enriched" "Detected in some" 4 "Intestinal goblet cells: 125.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Uncertain "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" 4.1 0.4 1.2 0.7 1.3 0.1 1.3 0.6 1.2 0.1 0.3 8.3 0.5 0.0 0.0 0.2 1.0 0.5 0.3 1.0 1.8 0.1 0.4 3.6 0.2 0.6 0.8 0.0 0.6 0.1 11.0 0.1 0.5 0.1 11.4 0.2 0.1 0.0 0.3 0.9 0.6 0.2 0.3 0.1 0.5 1.5 2.6 0.3 0.1 0.1 0.1 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 12.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 1.2 1.3 0.6 1.2 1.0 1.8 0.6 0.8 0.5 0.3 2.6 0.7 0.2 0.0 0.5 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.2 0.8 0.4 7.2 0.6 0.0 0.0 0.2 0.0 28.1 0.0 0.8 27.8 0.1 0.0 0.3 20.9 0.0 3.2 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 7.4 0.0 2.0 125.7 0.0 7.2 4.4 16.7 0.6 7.6 1.8 3.7 0.5 0.0 0.0 0.0 0.3 0.9 23.0 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.3 FGD2 ZFYVE4 ENSG00000146192 "FYVE, RhoGEF and PH domain containing 2" Q7Z6J4 6 37005646-37029069 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.7" "Cell type enhanced" "Detected in many" "B-cells: 53.7;dendritic cells: 29.7;Kupffer cells: 118.2;Langerhans cells: 49.3;Macrophages: 52.0;Microglial cells: 43.1;monocytes: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 22.3;intermediate monocyte: 64.8;memory B-cell: 23.2;myeloid DC: 35.0;naive B-cell: 18.6;non-classical monocyte: 70.5;plasmacytoid DC: 27.4" "Group enriched" "Detected in many" 18 "B-cells: 23.2;dendritic cells: 35.0;monocytes: 70.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;Daudi: 11.5;HDLM-2: 11.3;U-698: 9.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029145, HPA049692" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA029145: AB_10601321, HPA049692: AB_2680852" "unprognostic (3.54e-2)" "unprognostic (1.40e-4)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.67e-4)" "unprognostic (7.97e-2)" "unprognostic (1.58e-2)" "unprognostic (2.47e-2)" "unprognostic (2.78e-1)" "unprognostic (3.39e-2)" "unprognostic (2.82e-1)" "unprognostic (1.15e-2)" "unprognostic (3.91e-1)" "unprognostic (1.02e-2)" "unprognostic (3.88e-1)" "unprognostic (7.10e-2)" 6.1 3.3 1.0 14.8 1.3 6.0 2.6 1.2 1.3 1.5 2.3 3.4 3.7 1.3 1.5 2.4 2.8 4.1 1.6 1.0 1.6 1.4 2.5 8.0 22.5 3.2 1.7 1.0 1.3 0.3 1.1 2.7 1.9 1.5 2.7 0.1 2.3 1.8 0.6 2.1 11.1 4.7 2.1 39.7 3.8 0.6 2.1 5.5 2.7 0.9 9.8 4.5 1.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 11.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 22.3 2.3 0.1 64.8 0.1 23.2 0.0 0.0 35.0 18.6 0.0 0.0 0.3 0.4 70.5 27.4 0.1 7.5 1.0 1.3 1.2 1.3 1.0 1.6 3.2 1.7 1.9 2.1 2.1 2.0 0.3 6.4 7.4 0.0 53.7 2.0 3.0 1.0 0.6 0.3 0.7 0.6 3.2 2.8 0.5 0.0 0.0 0.3 29.7 0.3 0.0 2.8 11.9 0.5 0.2 1.2 0.0 1.3 0.1 0.9 0.4 1.0 1.5 1.2 7.6 0.0 2.5 0.6 17.7 0.0 0.2 0.1 4.1 118.2 49.3 2.1 1.5 52.0 1.8 43.1 51.8 0.4 2.1 0.5 0.2 1.0 3.9 0.0 14.2 1.6 0.1 0.2 3.2 0.2 0.0 2.3 0.5 0.0 0.1 3.3 2.3 0.4 3.0 0.1 0.4 5.6 FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Granulosa cells: 30.9;Hepatocytes: 37.5;Muller glia cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-251 MG: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 7: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" 38.1 56.0 40.8 5.0 43.3 7.6 24.1 40.6 49.5 15.7 29.8 10.2 7.3 9.9 3.4 5.5 36.0 9.3 19.8 39.2 33.5 25.4 52.8 15.1 3.1 49.9 45.8 25.4 71.6 16.1 21.6 3.0 46.5 12.4 4.9 10.5 37.6 2.7 20.6 10.7 13.5 4.0 42.2 9.1 27.2 5.5 47.9 1.4 67.1 9.6 2.2 11.2 8.0 42.1 23.2 31.6 11.3 34.3 11.9 12.3 2.9 40.4 6.2 12.9 8.4 23.1 47.9 2.6 49.3 63.3 58.3 5.8 21.8 14.1 11.8 8.3 21.0 0.3 41.2 61.5 24.0 13.7 5.6 25.7 11.7 22.4 9.5 48.4 12.5 9.3 25.3 8.9 7.9 30.8 16.0 37.7 14.2 39.7 83.8 24.7 16.3 16.7 22.6 3.6 1.2 2.2 38.1 0.8 15.2 13.4 22.5 11.9 26.1 68.8 27.2 35.2 99.8 8.9 12.9 3.8 18.1 15.6 22.8 0.6 0.0 0.0 0.2 1.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 40.8 43.3 40.6 49.5 39.2 33.5 49.9 45.8 46.5 42.2 47.9 42.1 3.8 3.2 4.1 34.0 2.8 6.5 3.7 5.4 2.2 5.4 13.2 6.1 8.5 11.5 6.9 7.3 0.0 1.6 4.1 4.4 0.0 9.6 0.2 6.0 4.2 2.6 1.8 4.8 3.2 10.2 26.6 5.1 6.6 13.5 1.3 30.9 5.3 37.5 3.2 0.0 2.8 11.0 0.0 1.6 2.5 1.2 4.4 3.4 7.2 1.9 1.3 94.0 1.0 5.0 5.4 19.9 2.7 3.4 2.2 11.4 2.9 7.6 7.0 5.6 0.0 3.3 5.1 0.4 4.2 1.2 4.7 1.5 4.2 17.5 3.6 8.8 FITM2 "C20orf142, dJ881L22.2, FIT2" ENSG00000197296 "Fat storage inducing transmembrane protein 2" Q8N6M3 20 44302840-44311202 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 67.4" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.92e-2)" "unprognostic (7.61e-2)" "unprognostic (2.27e-2)" "unprognostic (2.10e-3)" "unprognostic (1.02e-1)" "unprognostic (3.57e-3)" "unprognostic (1.63e-2)" "unprognostic (3.90e-2)" "unprognostic (8.43e-2)" "unprognostic (5.19e-2)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "prognostic favorable (8.98e-12)" "unprognostic (2.07e-1)" "unprognostic (2.54e-1)" "unprognostic (3.38e-3)" "unprognostic (2.49e-3)" 11.4 11.1 4.8 2.9 5.0 1.2 7.0 5.7 6.3 4.2 5.9 5.2 4.3 4.0 8.7 3.3 3.7 3.2 67.4 4.8 5.9 7.9 6.4 4.1 2.2 6.9 5.9 4.6 7.4 13.6 5.2 1.9 7.4 6.4 6.0 6.7 6.5 4.4 9.2 5.7 3.9 5.3 4.2 2.6 4.6 3.8 5.4 1.7 6.3 16.8 2.6 4.5 3.1 4.7 7.2 10.9 4.5 6.6 31.4 12.8 4.6 11.5 8.4 8.9 4.9 13.5 5.1 4.9 6.5 13.0 14.3 15.8 5.7 7.7 9.6 1.4 2.7 1.6 6.5 22.9 6.6 3.1 4.0 9.7 17.2 6.2 4.7 4.9 6.4 3.1 2.7 14.2 9.1 22.4 1.2 3.4 1.1 10.8 13.9 1.9 8.4 4.9 5.1 6.7 2.7 3.2 24.4 13.5 10.3 2.0 16.5 2.4 7.9 28.2 12.6 16.6 6.8 5.2 14.4 1.3 12.6 4.9 14.4 0.7 1.0 0.6 1.1 1.0 1.2 0.6 1.2 0.9 1.0 0.6 2.0 1.6 0.4 1.4 0.8 0.6 1.2 0.9 4.8 5.0 5.7 6.3 4.8 5.9 6.9 5.9 7.4 4.2 5.4 4.7 2.8 6.4 9.7 1.3 3.6 6.9 3.5 2.8 1.2 6.4 5.0 3.4 153.9 11.5 4.3 5.5 6.2 2.0 1.0 5.1 1.9 5.2 4.6 2.2 5.0 4.4 9.1 0.8 2.3 8.6 3.5 9.4 4.1 2.1 0.0 4.4 8.2 14.1 3.4 6.7 2.1 4.8 0.0 3.8 2.2 1.2 7.8 1.7 7.2 1.0 2.3 6.6 2.1 4.0 0.9 5.7 4.1 7.5 3.1 3.1 5.9 6.2 4.0 5.9 0.0 5.6 6.3 9.1 6.0 2.7 8.1 1.5 2.1 16.3 9.2 2.2 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FOXN4 ENSG00000139445 "Forkhead box N4" Q96NZ1 12 109277978-109309284 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 11.4" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Endometrial ciliated cells: 2.6;Ionocytes: 2.0;Respiratory ciliated cells: 1.2;Spermatocytes: 2.8;Spermatogonia: 3.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SCLC-21H: 3.5;SH-SY5Y: 3.6;U-266/70: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA050018 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Mitochondria" Cytosol "HPA050018: AB_2680992" "unprognostic (1.09e-3)" "unprognostic (9.63e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (2.52e-2)" "unprognostic (1.18e-1)" "unprognostic (3.27e-2)" "unprognostic (7.93e-3)" "unprognostic (2.30e-1)" "unprognostic (1.02e-3)" "unprognostic (1.05e-1)" "unprognostic (1.43e-1)" "unprognostic (6.00e-2)" 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.2 1.8 0.5 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.3 0.8 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 11.4 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.1 2.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.2" "Group enriched" "Detected in some" 15 "Hofbauer cells: 56.5;Kupffer cells: 97.4;Langerhans cells: 223.6;Macrophages: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 44 "dendritic cells: 2.4;monocytes: 6.7" "Group enriched" "Detected in some" 5 "HEL: 10.0;hTERT-RPE1: 2.7" "Not detected" "Not detected" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" 10.6 12.1 0.6 23.9 1.1 0.4 5.3 0.5 2.4 5.5 2.2 12.6 11.2 3.7 1.5 5.7 2.0 18.8 3.8 0.6 0.7 3.2 21.3 28.2 13.9 3.1 1.0 1.7 2.3 2.2 0.9 5.6 2.8 2.5 18.2 0.3 2.4 2.9 0.9 2.7 14.4 8.9 1.2 16.3 7.1 2.7 6.0 8.1 2.2 2.0 11.0 17.4 1.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.6 1.1 0.5 2.4 0.6 0.7 3.1 1.0 2.8 1.2 6.0 3.9 0.5 0.0 1.7 0.3 2.7 5.6 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.0 2.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 1.5 56.5 0.0 0.2 0.0 0.0 97.4 223.6 0.2 0.3 66.6 7.2 1.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.4 0.1 0.0 0.0 1.5 0.1 0.0 0.3 0.5 0.0 0.1 0.4 4.5 0.8 0.6 0.0 0.0 0.1 FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.6;Cardiomyocytes: 73.7;Cone photoreceptor cells: 79.2;Early spermatids: 121.9;Horizontal cells: 101.0;Late spermatids: 122.8;Sertoli cells: 72.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Cell line enhanced" "Detected in many" "HEL: 24.0;OE19: 49.2;RPMI-8226: 79.6;SCLC-21H: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" 9.4 7.3 6.6 2.0 5.5 5.4 6.7 4.3 6.8 3.0 12.0 5.5 2.9 2.7 15.7 2.5 2.2 2.5 85.0 6.3 7.7 14.9 0.7 4.0 1.3 10.1 8.5 1.4 1.6 20.6 4.2 14.8 7.3 2.8 6.6 21.6 2.9 7.8 81.2 2.1 6.7 3.5 7.6 7.2 2.8 9.9 9.9 1.1 7.1 74.7 0.5 4.6 2.6 5.4 0.0 4.3 3.8 0.3 0.7 0.2 0.3 4.1 0.3 0.1 0.0 0.5 5.2 0.9 4.7 1.9 0.9 0.2 0.2 0.0 0.0 0.2 0.2 24.0 4.8 2.8 0.2 0.0 0.3 1.0 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.1 4.9 0.7 0.0 0.1 0.4 49.2 7.2 0.1 3.0 79.6 6.2 10.1 28.4 13.8 1.4 0.3 0.9 0.6 1.7 0.8 4.4 0.2 0.6 0.1 2.9 0.4 0.3 0.0 0.9 7.6 2.8 0.0 2.0 0.0 0.2 3.4 0.4 0.3 0.1 0.0 0.2 0.4 0.0 0.0 2.5 0.3 1.5 0.4 0.0 6.0 6.6 5.5 4.3 6.8 6.3 7.7 10.1 8.5 7.3 7.6 9.9 5.4 38.4 22.4 1.1 6.2 0.4 1.0 1.0 0.6 0.6 108.6 2.6 1.9 73.7 15.7 1.8 1.8 79.2 0.4 0.2 28.9 17.6 2.8 121.9 2.8 1.4 25.8 1.2 0.8 37.9 2.0 1.2 8.8 2.0 3.9 0.0 0.4 4.2 0.3 0.8 101.0 70.0 38.3 0.0 4.4 0.6 122.8 2.1 8.3 0.0 27.2 4.2 3.9 1.0 10.1 16.0 2.3 10.0 4.9 0.0 1.6 43.6 12.4 3.2 7.0 72.3 66.6 50.7 4.1 1.4 0.2 1.3 0.1 0.9 29.8 2.4 2.3 FRMD4A "bA295P9.4, FLJ10210, FRMD4, KIAA1294" ENSG00000151474 "FERM domain containing 4A" Q9P2Q2 10 13643706-14462142 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 60.8" "Group enriched" "Detected in many" 7 "Excitatory neurons: 1527.6;Inhibitory neurons: 1622.8;Microglial cells: 1329.4;Oligodendrocyte precursor cells: 442.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.3" "Lineage enriched" "Detected in single" 5 "B-cells: 2.3" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 134.0;HUVEC TERT2: 105.8;TIME: 191.6;WM-115: 163.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038449 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA038449: AB_10669539" "unprognostic (6.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.51e-3)" "unprognostic (5.68e-2)" "unprognostic (1.55e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.21e-3)" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (9.20e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" "unprognostic (8.16e-2)" "unprognostic (1.84e-1)" 60.8 5.2 38.9 11.7 28.1 5.4 18.7 0.0 29.2 8.6 0.0 13.1 5.7 5.7 4.0 9.4 8.8 9.6 16.7 24.1 8.5 19.5 12.2 14.2 9.1 15.6 10.9 6.8 15.5 2.4 8.7 22.5 6.2 10.3 6.4 14.1 13.6 10.2 8.1 32.0 7.4 6.5 10.0 32.8 7.9 8.8 14.4 15.6 8.1 7.3 8.4 10.4 8.9 18.9 7.0 7.1 90.1 0.5 12.3 22.0 16.9 40.8 36.5 35.2 48.7 12.1 4.2 0.1 28.3 21.5 48.6 13.5 0.3 3.3 30.7 0.3 9.9 1.4 0.9 0.2 11.0 0.5 1.1 12.8 3.2 134.0 16.4 98.9 105.8 3.1 13.6 0.4 64.7 8.5 4.6 0.8 24.6 0.3 9.6 0.4 30.8 0.2 16.6 5.8 4.3 15.9 0.2 32.7 64.4 16.1 18.5 3.3 191.6 48.8 17.4 47.6 49.3 0.3 0.4 0.3 41.7 1.0 163.4 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.3 0.1 0.0 2.3 0.3 0.0 0.3 0.2 0.0 0.4 0.4 0.0 38.9 28.1 0.0 29.2 24.1 8.5 15.6 10.9 6.2 10.0 14.4 18.9 48.6 32.1 2.6 168.1 1.7 35.1 13.1 3.0 9.1 54.2 17.1 14.4 11.4 45.8 4.1 33.1 18.8 69.6 0.4 1.1 11.7 15.8 42.5 13.1 5.5 44.0 4.8 81.7 1527.6 4.0 42.1 14.9 4.6 26.9 15.2 58.1 44.3 6.2 35.9 80.8 1622.8 3.4 6.1 95.6 19.9 98.8 2.1 25.5 16.0 1329.4 2.7 46.0 0.0 442.3 61.0 1.8 1.4 1.9 0.9 8.0 0.3 2.7 2.5 12.9 13.1 41.2 45.5 1.3 2.1 20.6 32.7 28.7 3.0 5.3 5.4 4.3 FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.1;Hepatocytes: 651.7;Leydig cells: 430.3;Muller glia cells: 343.4;Skeletal myocytes: 188.7;Smooth muscle cells: 205.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Cell line enhanced" "Detected in some" "ASC diff: 46.7;ASC TERT1: 13.5;HSkMC: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" 141.4 26.1 496.5 9.6 528.9 2.2 125.1 506.1 637.3 291.9 616.5 168.3 14.3 173.3 62.1 70.7 187.3 56.3 557.7 487.5 503.4 28.6 558.7 85.8 6.6 568.0 515.0 144.7 19.2 3.8 39.8 29.3 494.8 116.0 25.6 35.9 37.2 73.5 1381.3 48.3 67.2 104.5 511.1 20.8 72.6 12.1 560.2 8.2 38.0 838.7 6.7 80.0 194.9 498.6 1.1 0.0 0.0 0.2 46.7 13.5 1.3 5.7 0.1 0.0 0.0 0.0 0.3 3.8 1.5 0.0 0.1 1.0 1.1 0.7 0.0 3.4 1.3 0.7 0.0 1.9 5.2 0.3 0.4 19.3 0.0 0.1 0.5 0.5 0.2 0.1 1.0 3.7 0.1 0.0 0.1 0.8 0.2 2.8 0.6 0.0 0.2 1.1 0.0 0.0 0.3 0.2 0.7 0.2 1.8 0.3 0.2 6.1 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.4 0.9 0.6 7.7 1.6 0.3 0.0 1.3 0.7 0.8 11.0 3.6 1.5 0.3 6.9 0.7 0.9 0.5 2.1 0.8 0.6 6.9 0.6 496.5 528.9 506.1 637.3 487.5 503.4 568.0 515.0 494.8 511.1 560.2 498.6 46.1 0.0 0.0 44.4 15.8 29.4 3.7 2.7 8.0 1.8 4.4 18.0 0.3 11.5 0.8 25.8 4.2 1.2 9.5 42.2 0.0 0.1 1.9 2.2 47.4 13.3 0.0 8.4 3.7 4.9 1.6 225.1 2.0 1.2 0.0 0.1 36.0 651.7 4.4 0.0 0.4 0.8 2.0 14.4 49.0 12.0 430.3 5.3 53.4 2.8 1.0 343.4 1.0 1.5 0.5 1.1 5.3 128.2 2.5 3.3 0.4 0.2 12.6 8.6 118.3 188.7 205.7 10.7 21.7 3.0 27.3 2.9 18.8 0.1 0.7 2.5 FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 120.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.0;Collecting duct cells: 36.8;Endothelial cells: 51.2;Hepatic stellate cells: 99.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 63.6;Hep G2: 85.2;HSkMC: 46.0;HUVEC TERT2: 93.6;TIME: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" 120.1 9.5 6.7 5.8 6.2 0.3 55.6 5.1 7.3 12.5 7.8 14.9 2.8 12.2 7.6 6.5 16.3 11.5 27.4 5.6 5.9 27.1 14.6 32.9 6.2 6.5 6.3 12.9 9.5 6.4 8.7 11.7 7.0 12.5 6.3 1.1 12.2 30.2 31.5 5.9 8.8 13.4 5.6 14.1 14.1 5.1 8.5 3.9 18.1 40.6 4.6 10.5 9.5 5.9 1.3 1.1 2.7 5.2 63.6 16.5 3.7 8.4 7.6 3.2 3.3 7.1 0.9 0.0 1.8 2.6 4.4 2.8 3.1 1.3 2.5 0.2 2.1 2.8 2.3 85.2 18.9 0.0 0.1 46.0 0.5 2.8 0.5 7.5 93.6 0.1 3.9 0.4 2.2 2.2 0.0 0.0 3.9 7.5 18.8 0.1 4.8 0.2 9.0 13.7 0.6 0.8 3.5 1.0 1.4 5.6 12.0 0.0 46.3 7.8 5.1 9.2 1.7 0.4 1.3 0.0 1.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 5.1 7.3 5.6 5.9 6.5 6.3 7.0 5.6 8.5 5.9 83.0 0.0 1.3 9.8 0.5 1.5 0.5 1.3 2.2 0.7 5.5 3.2 8.3 7.2 2.0 36.8 10.4 0.2 0.5 1.0 3.9 0.5 0.7 0.4 2.7 51.2 0.0 2.7 8.1 1.6 0.2 17.7 4.1 0.5 0.0 9.1 99.6 14.1 0.2 0.0 3.4 1.3 0.0 6.7 1.8 2.2 9.3 0.6 0.0 10.3 0.0 0.2 2.1 3.0 0.7 1.0 0.1 6.8 0.3 1.4 0.7 9.4 2.1 0.2 32.9 14.4 26.6 0.3 3.2 1.3 0.6 0.3 0.4 16.6 1.1 0.2 FZD5 "C2orf31, DKFZP434E2135, HFZ5" ENSG00000163251 "Frizzled class receptor 5" Q13467 2 207762598-207769906 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 23.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 117.4;Hepatocytes: 59.8;Intestinal goblet cells: 50.1;Muller glia cells: 50.7;Undifferentiated cells: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 104.7;CACO-2: 26.2;Hep G2: 36.5;NTERA-2: 31.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052361 Approved NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052361: AB_2681799" "unprognostic (4.97e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" "unprognostic (1.53e-1)" "unprognostic (2.82e-1)" "unprognostic (4.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-3)" "unprognostic (1.29e-1)" "unprognostic (8.00e-2)" "unprognostic (7.72e-2)" "unprognostic (2.51e-1)" "unprognostic (9.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.15e-3)" 6.0 5.0 1.8 2.5 3.5 4.2 2.4 1.8 3.6 3.0 3.5 18.3 18.6 2.3 0.6 3.3 1.2 1.4 1.6 1.7 3.6 5.1 23.5 6.7 1.1 3.2 4.9 4.2 10.4 1.0 4.7 4.4 2.5 6.3 14.7 10.9 3.1 2.7 2.6 1.0 15.3 2.6 1.8 2.0 11.2 0.4 2.7 1.5 8.7 2.0 1.4 1.7 2.3 6.2 3.3 5.8 0.3 3.1 2.6 0.1 104.7 0.5 0.7 0.8 0.7 26.2 6.0 0.6 7.0 0.3 2.0 4.8 9.0 3.9 0.7 0.4 6.9 7.6 2.8 36.5 2.0 1.5 2.0 0.2 3.7 1.2 3.0 2.0 1.0 1.1 15.5 1.2 0.7 2.3 0.8 1.9 31.0 14.2 2.0 1.9 3.3 1.4 7.3 11.4 5.0 0.7 1.4 0.6 1.5 14.1 1.7 1.5 0.4 1.6 3.0 3.2 2.5 1.7 4.1 1.3 2.1 1.7 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.5 1.8 3.6 1.7 3.6 3.2 4.9 2.5 1.8 2.7 6.2 6.5 32.1 32.6 4.6 2.0 5.1 5.4 5.4 6.2 2.2 8.7 3.7 7.8 25.8 4.8 1.8 33.3 18.9 1.6 117.4 0.0 14.9 0.7 9.0 2.2 4.1 12.6 15.1 0.5 24.7 6.0 3.2 17.3 18.8 0.0 16.8 2.9 59.8 10.5 6.7 0.9 50.1 6.1 8.4 9.8 0.1 1.8 3.3 1.8 1.0 0.7 50.7 0.0 0.0 6.0 18.2 38.6 0.4 0.5 12.5 43.2 12.2 3.4 7.0 0.0 8.1 4.5 1.5 2.1 4.0 4.1 4.0 1.4 8.1 57.6 5.9 G0S2 ENSG00000123689 "G0/G1 switch 2" P27469 1 209675412-209676390 "Metabolic proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 796.7;bone marrow: 1345.4" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 5188.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 44.5" "Immune cell enriched" "Detected in some" 60 "neutrophil: 549.5" "Lineage enriched" "Detected in many" 213 "granulocytes: 549.5" "Cell line enhanced" "Detected in many" "ASC diff: 460.8;HBEC3-KT: 726.2;PC-3: 180.6;RPMI-8226: 242.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "unprognostic (1.67e-3)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.82e-1)" "unprognostic (2.21e-1)" "unprognostic (5.04e-3)" "unprognostic (3.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.32e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (7.57e-3)" "unprognostic (1.53e-2)" "unprognostic (4.78e-2)" "unprognostic (2.64e-1)" 796.7 194.3 7.0 95.7 7.5 1345.4 519.5 7.4 44.5 9.2 8.2 20.9 7.6 34.3 11.7 8.6 26.8 15.7 175.9 8.8 6.8 262.6 664.6 318.4 7.6 7.4 8.6 47.5 31.0 0.8 9.5 13.8 9.1 38.3 4.0 0.6 59.8 14.8 651.4 24.3 31.7 10.9 7.9 49.3 63.8 30.1 7.8 5.9 23.7 303.4 5.4 136.2 17.3 9.7 0.0 4.3 0.0 0.0 460.8 16.1 0.3 0.7 1.4 1.9 1.8 19.3 14.8 0.0 4.1 3.4 2.5 0.0 0.0 726.2 4.4 0.7 1.2 0.0 1.5 0.6 37.5 0.2 0.1 47.8 1.6 32.4 0.0 15.8 0.0 0.0 0.2 0.0 0.2 0.0 0.2 15.7 1.3 0.0 180.6 0.0 0.0 242.8 1.7 0.3 0.9 1.4 16.3 0.0 4.0 0.0 0.2 56.7 73.6 0.0 4.9 0.2 0.1 0.0 1.1 0.1 13.1 0.1 0.0 0.0 1.0 9.1 0.0 1.1 0.4 0.1 2.5 0.1 0.3 0.3 0.0 0.0 549.5 0.0 0.2 0.0 0.0 0.4 7.0 7.5 7.4 44.5 8.8 6.8 7.4 8.6 9.1 7.9 7.8 9.7 52.3 9.6 59.5 5.9 16.1 232.4 654.8 760.7 124.1 0.6 295.2 43.3 359.1 14.3 111.6 11.0 0.0 1.8 5.0 16.6 299.3 52.3 25.3 42.7 12.0 264.5 29.3 6.9 0.9 148.2 3.6 730.2 11.7 112.0 39.1 34.7 12.1 179.4 174.2 0.0 3.1 32.6 22.4 78.2 5188.4 12.3 114.6 1060.3 327.3 2.8 30.7 23.1 1.0 11.1 0.9 736.5 42.9 71.5 10.3 416.7 41.1 304.9 42.3 0.3 32.9 56.4 60.1 52.1 1.1 35.2 161.4 4.2 33.3 7.5 52.5 513.7 GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.5;epididymis: 8.8" "Group enriched" "Detected in many" 5 "Astrocytes: 425.4;Excitatory neurons: 156.2;Inhibitory neurons: 111.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "U-2 OS: 4.2;U-87 MG: 2.1;WM-115: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Uncertain "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (2.45e-4)" "unprognostic (6.87e-3)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.09e-1)" "unprognostic (6.90e-3)" "unprognostic (8.83e-2)" "unprognostic (2.22e-5)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 1.2 0.3 20.2 0.4 29.9 0.2 1.3 2.6 31.5 0.5 0.0 3.0 0.9 0.4 8.8 0.7 0.0 0.5 0.2 29.4 16.0 6.3 0.4 0.1 0.3 0.3 1.9 0.7 0.1 0.0 0.5 0.4 0.0 0.1 2.1 2.4 0.2 0.7 0.1 0.2 6.0 0.2 1.3 1.2 0.5 0.5 13.8 0.4 0.1 0.1 0.4 0.2 0.7 8.8 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 4.2 0.2 0.0 0.2 0.6 0.0 2.1 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 29.9 2.6 31.5 29.4 16.0 0.3 1.9 0.0 1.3 13.8 8.8 4.9 0.0 0.0 425.4 0.0 0.1 0.0 0.0 1.2 15.3 0.2 0.0 0.6 0.0 0.0 40.5 4.2 0.0 0.0 23.1 3.9 0.0 9.1 1.2 31.7 1.0 31.8 0.0 156.2 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 111.6 3.4 0.0 0.0 0.0 17.1 0.6 0.1 1.8 16.9 0.0 0.2 0.0 13.0 5.5 0.0 4.7 0.0 0.0 0.0 38.1 0.1 0.0 1.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.0 2.7 0.0 GABRE ENSG00000102287 "Gamma-aminobutyric acid type A receptor subunit epsilon" P78334 X 151953124-151974680 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "brain: 52.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.7;Syncytiotrophoblasts: 61.4;Urothelial cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.4;EFO-21: 11.6;HeLa: 6.1;SiHa: 5.6" "Region enriched" "Detected in many" 4 "hypothalamus: 18.4" "Region enhanced" "Detected in many" "hypothalamus: 32.3" HPA045918 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA045918: AB_10961281" "unprognostic (1.33e-2)" "unprognostic (6.75e-2)" "unprognostic (3.50e-3)" "unprognostic (1.39e-3)" "unprognostic (2.43e-1)" "unprognostic (7.52e-2)" "unprognostic (5.06e-3)" "unprognostic (1.27e-1)" "unprognostic (3.58e-2)" "unprognostic (1.55e-1)" "unprognostic (6.44e-2)" "unprognostic (6.73e-2)" "prognostic unfavorable (4.05e-11)" "unprognostic (1.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (5.28e-2)" 9.7 0.4 6.3 0.3 4.5 0.0 4.4 0.0 9.7 1.7 0.9 0.4 0.7 0.6 1.8 1.0 0.7 0.5 9.5 0.8 52.3 1.1 0.1 0.6 0.2 5.1 38.0 0.8 0.8 0.9 2.2 3.3 33.0 1.8 0.3 0.1 0.8 3.4 0.3 3.2 0.4 0.3 0.2 0.2 0.3 0.1 14.0 0.1 1.0 0.0 0.2 0.6 2.3 0.2 0.2 0.0 0.1 0.0 3.4 0.0 0.0 0.5 0.0 0.8 0.4 1.9 0.6 0.0 11.6 2.5 0.0 1.9 0.0 0.6 0.5 0.0 0.4 1.3 6.1 0.7 0.2 0.0 0.1 0.8 0.5 0.9 0.2 1.1 0.4 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.7 0.0 0.8 0.0 0.0 1.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 4.5 0.0 9.7 0.8 52.3 5.1 38.0 33.0 0.2 14.0 0.2 7.7 16.0 9.3 0.7 0.7 17.2 22.9 18.6 30.7 0.0 6.8 4.6 7.3 11.5 25.2 1.8 0.0 25.0 0.5 10.0 0.0 4.1 2.0 7.6 12.8 9.0 1.8 0.0 0.0 0.4 3.5 9.2 0.0 29.2 0.0 0.1 4.2 0.9 3.0 0.0 0.0 2.3 4.1 0.6 4.6 3.5 1.5 0.3 1.8 2.8 0.7 0.6 1.0 0.0 0.0 6.1 7.4 2.2 0.0 19.2 21.6 0.2 5.6 0.3 0.0 19.6 5.7 1.2 2.1 22.5 10.9 61.4 1.3 0.1 3.6 42.2 GAS1 ENSG00000180447 "Growth arrest specific 1" P54826 9 86944362-86947506 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 105.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 127.1;Muller glia cells: 90.3;Skeletal myocytes: 213.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 30.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.2;ASC diff: 29.3;BJ hTERT+: 59.8;HSkMC: 41.1;RH-30: 91.1" "Low region specificity" "Detected in all" "CAB024164, HPA036085, HPA066902" Approved Approved "Nuclear speckles" NA NA 27000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "CAB024164: AB_2107950, HPA036085: AB_2674932, HPA066902: AB_2685746" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.97e-2)" "unprognostic (6.15e-2)" "unprognostic (2.84e-2)" "unprognostic (6.46e-2)" "unprognostic (6.91e-2)" "unprognostic (3.32e-1)" "unprognostic (1.28e-3)" "unprognostic (2.25e-3)" "unprognostic (4.30e-2)" "prognostic unfavorable (1.96e-5)" "prognostic unfavorable (8.26e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.13e-5)" "unprognostic (3.59e-2)" 81.5 6.4 3.6 16.6 4.4 0.2 38.3 3.5 4.4 27.1 16.1 27.6 2.2 105.4 15.2 5.8 60.7 10.5 27.1 3.2 2.7 12.5 2.2 7.8 6.8 3.8 3.8 45.1 11.2 1.9 8.4 22.1 3.6 22.6 2.3 3.3 13.1 9.6 12.2 22.2 9.3 43.4 3.4 3.6 16.3 1.8 3.8 7.1 15.9 9.3 3.1 22.5 27.1 6.8 0.0 0.0 7.5 44.2 29.3 10.9 0.8 8.8 59.8 2.9 2.6 0.0 0.1 0.0 0.5 15.8 0.3 0.6 0.0 0.3 1.2 5.2 17.8 0.0 25.0 0.0 14.9 0.1 0.7 41.1 6.3 1.0 5.3 0.0 0.0 0.9 0.0 0.0 12.6 0.0 0.0 0.4 9.5 0.3 0.1 9.6 91.1 0.0 0.4 0.0 1.0 4.0 12.9 0.0 14.1 4.8 0.1 0.2 0.1 13.0 3.6 0.9 3.0 0.0 0.0 0.0 0.4 0.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.4 3.5 4.4 3.2 2.7 3.8 3.8 3.6 3.4 3.8 6.8 15.8 0.0 0.6 2.0 0.4 25.9 7.5 10.9 10.2 8.3 3.9 28.3 5.5 0.0 3.1 14.7 10.4 21.5 7.8 0.1 9.8 0.5 0.1 2.4 36.6 5.6 0.0 0.4 1.2 0.4 3.7 127.1 1.1 2.0 0.0 2.1 22.9 0.3 5.8 5.0 2.6 0.3 0.0 1.0 15.4 0.9 32.3 2.2 17.8 1.9 0.2 90.3 7.2 8.5 4.4 0.2 0.0 12.4 2.1 4.5 0.0 2.6 0.7 3.2 39.5 213.7 15.4 0.3 1.3 1.0 12.5 4.5 2.1 0.8 0.2 0.4 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Cell type enhanced" "Detected in many" "dendritic cells: 39.2;NK-cells: 75.2;Plasma cells: 22.9;T-cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 6.5;NB-4: 10.0;U-266/70: 20.7;U-937: 31.5" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" 3.7 3.3 0.4 73.9 0.5 34.9 4.6 0.4 1.7 3.1 1.5 6.9 5.8 2.3 1.4 2.6 3.1 11.5 2.0 0.4 0.5 2.0 11.1 19.1 54.4 2.9 0.7 2.7 1.1 0.7 1.0 2.8 1.2 2.3 8.0 0.2 4.8 1.2 0.7 1.0 9.0 6.1 0.5 42.7 9.2 4.0 0.8 12.4 2.3 0.9 23.3 12.7 1.4 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.7 1.2 1.2 0.0 0.1 0.1 6.5 5.3 2.6 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.9 0.6 3.0 0.3 0.0 0.0 10.0 1.4 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.6 1.3 0.1 0.0 0.0 4.0 0.1 0.5 0.5 0.0 2.2 20.7 0.5 0.1 0.2 31.5 0.0 0.9 15.3 1.1 97.5 38.0 150.4 4.8 63.1 89.3 6.7 6.0 23.2 35.8 97.9 53.4 44.9 0.7 243.8 38.4 0.4 0.5 0.4 1.7 0.4 0.5 2.9 0.7 1.2 0.5 0.8 0.7 2.1 6.4 5.1 0.0 12.4 0.0 0.2 0.5 0.6 0.0 0.4 0.4 0.7 1.5 4.2 0.0 4.2 0.1 39.2 0.1 0.0 0.0 0.4 3.7 0.4 2.8 0.0 0.8 0.0 1.1 0.0 1.5 2.0 3.9 10.8 0.2 4.6 0.6 4.0 0.0 0.7 0.0 0.0 18.9 1.4 0.2 0.0 17.1 0.0 2.8 10.4 2.9 75.2 0.0 0.0 1.3 0.0 0.0 22.9 0.4 0.0 0.3 8.0 0.4 0.0 0.9 0.9 0.1 2.9 0.9 0.0 0.1 72.9 11.0 0.1 0.1 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" Neurogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 116.6;retina: 83.5" "Group enriched" "Detected in many" 4 "Bipolar cells: 60.9;Cone photoreceptor cells: 148.0;Early spermatids: 52.1;Late spermatids: 178.0;Rod photoreceptor cells: 88.4;Syncytiotrophoblasts: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Cell line enhanced" "Detected in many" "EFO-21: 32.8;fHDF/TERT166: 32.4;HDLM-2: 66.9;U-2 OS: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA065257: AB_2685447, HPA066762: AB_2685715, HPA069281: AB_2686107" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (9.97e-3)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-1)" "unprognostic (3.07e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.59e-9)" "unprognostic (8.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-1)" 31.0 8.7 19.5 4.8 22.1 12.8 24.6 17.4 12.9 12.4 6.0 7.3 2.7 17.9 1.8 3.3 10.3 4.3 9.5 10.5 14.5 7.8 8.1 15.2 6.7 14.2 27.0 7.3 38.1 0.8 19.1 14.0 10.2 11.5 1.6 83.5 21.3 5.3 13.1 7.4 10.0 6.5 7.4 116.6 4.8 38.9 42.1 3.1 7.7 8.7 4.7 12.6 9.9 12.4 2.1 7.5 3.2 3.7 2.2 1.1 11.1 2.3 3.1 1.1 0.7 10.0 4.4 14.2 32.8 32.4 8.1 4.7 4.0 3.8 0.6 66.9 3.1 2.6 11.7 21.2 3.2 1.6 10.7 2.4 2.0 0.8 1.6 3.2 26.7 12.7 4.7 6.3 1.5 4.5 3.9 7.1 5.7 3.7 10.6 4.5 0.9 3.9 0.9 3.6 1.7 1.2 4.8 18.3 9.3 4.1 2.7 6.3 7.9 7.5 30.4 5.8 2.6 1.6 0.3 2.8 1.7 8.5 0.8 7.7 0.8 0.5 1.2 0.3 1.7 0.6 1.3 0.9 0.2 0.2 0.7 0.9 0.1 0.0 0.0 0.7 2.0 0.5 19.5 22.1 17.4 12.9 10.5 14.5 14.2 27.0 10.2 7.4 42.1 12.4 4.2 6.4 0.0 1.6 5.4 1.0 0.3 0.7 0.6 60.9 3.6 3.4 3.0 1.5 1.3 0.0 148.0 3.2 9.1 0.5 0.0 4.2 52.1 1.0 10.4 7.0 0.0 8.2 5.0 9.3 1.5 6.6 1.1 1.5 4.5 1.6 20.7 2.4 1.9 5.0 15.8 0.7 0.0 2.8 3.7 178.0 5.9 3.1 5.4 8.4 4.9 8.9 1.0 1.0 0.8 4.7 0.3 2.6 5.0 0.8 0.3 0.1 0.8 88.4 0.0 4.6 1.9 12.9 8.2 0.1 1.1 46.0 7.0 0.9 2.0 0.6 GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;liver: 213.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.3;Hepatocytes: 141.3;Inhibitory neurons: 115.7;Oligodendrocyte precursor cells: 181.0" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HSkMC: 21.2;T-47d: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 2200000 24000000 "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" 84.7 5.6 1.8 1.7 2.1 0.2 30.1 1.7 1.7 5.2 2.3 5.8 1.1 4.5 4.6 3.9 5.4 5.2 8.9 1.8 5.6 11.8 213.3 4.0 1.3 1.0 2.0 7.5 2.1 5.5 1.2 4.8 1.4 11.1 5.7 0.4 3.7 4.7 45.7 5.6 4.3 4.0 1.1 4.0 6.1 1.7 3.4 2.3 4.6 11.6 0.9 5.0 5.8 1.4 0.0 0.0 0.6 5.0 3.3 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.3 4.3 0.0 0.0 2.6 0.0 0.1 0.0 0.6 0.0 0.0 21.2 7.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 3.5 0.6 56.0 0.1 3.0 4.8 2.1 2.6 0.5 0.5 0.0 0.0 0.5 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.7 1.7 1.8 5.6 1.0 2.0 1.4 1.1 3.4 1.4 17.2 0.0 0.5 14.7 0.4 4.7 4.5 17.8 10.2 0.6 9.7 16.0 18.6 1.5 1.9 1.8 0.0 17.4 0.5 2.8 1.9 0.0 5.1 0.5 9.4 4.8 3.0 5.3 53.3 0.2 2.2 23.8 0.5 0.3 0.0 1.1 6.1 141.3 1.9 0.0 115.7 1.9 0.0 3.0 1.8 2.8 18.6 0.7 1.8 36.5 0.0 0.7 0.0 181.0 3.6 0.2 1.7 12.0 0.0 5.2 0.0 9.6 0.6 0.4 13.1 18.7 15.1 0.7 0.3 2.9 3.7 40.2 0.5 49.4 2.2 0.9 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIPC3 "C19orf64, DFNB15, DFNB72, DFNB95" ENSG00000179855 "GIPC PDZ domain containing family member 3" Q8TF64 19 3585478-3593541 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.7" "Group enriched" "Detected in some" 4 "Adipocytes: 10.4;Endothelial cells: 6.2;Hepatic stellate cells: 12.8;Rod photoreceptor cells: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 19.0;HMC-1: 11.8;THP-1: 23.1;WM-115: 44.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA067765 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA067765: " "unprognostic (1.77e-1)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (6.99e-2)" "unprognostic (1.22e-1)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (3.67e-3)" "unprognostic (4.76e-2)" "unprognostic (2.97e-1)" "unprognostic (5.06e-3)" "unprognostic (2.26e-2)" "unprognostic (1.51e-3)" "unprognostic (1.96e-2)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (9.06e-2)" 4.6 2.2 1.4 1.0 1.0 0.3 2.8 1.0 1.1 3.0 0.8 1.9 1.2 2.8 2.9 5.2 2.1 2.1 3.9 1.2 1.2 3.6 1.4 3.8 2.4 1.6 1.2 0.7 0.7 2.7 1.0 1.1 1.6 3.5 1.4 16.7 0.7 2.3 1.7 1.1 4.4 8.3 1.4 3.9 2.0 0.3 1.6 3.1 3.0 1.9 1.6 1.1 1.8 1.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.9 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.4 0.0 1.5 0.0 0.2 6.9 19.0 0.0 0.7 0.0 11.8 0.2 0.0 1.1 0.0 0.0 2.1 0.2 3.2 0.0 0.3 0.0 0.0 1.1 0.7 0.0 1.2 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.5 0.0 4.7 1.1 0.0 23.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 44.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.0 1.1 1.2 1.2 1.6 1.2 1.6 1.4 1.6 1.1 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.4 0.1 0.3 2.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 12.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.2 1.1 0.0 0.4 0.1 0.3 0.1 0.3 0.1 0.0 0.1 GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 6.4;Leydig cells: 3.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 78.1" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" 8.1 0.3 0.4 0.7 3.0 0.0 0.8 0.0 3.6 6.0 0.0 13.5 9.9 1.2 0.0 0.7 1.6 12.2 0.6 3.2 0.0 0.3 2.7 1.0 0.6 0.0 0.2 0.4 1.6 0.0 0.0 1.1 0.0 0.1 6.0 3.4 0.0 0.1 0.1 0.1 8.2 1.9 0.0 0.1 3.7 0.4 0.0 0.1 0.2 0.2 0.2 11.8 1.5 1.7 0.0 16.6 0.0 0.0 0.8 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 78.1 0.6 1.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 3.6 3.2 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 6.4 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 23.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 1903.6;Endothelial cells: 1236.2;Hepatic stellate cells: 994.2;Macrophages: 481.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cell line enhanced" "Detected in many" "EFO-21: 219.9;HUVEC TERT2: 349.6;SK-MEL-30: 221.8;TIME: 201.1;U-87 MG: 187.1" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 3400000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA045255: AB_10794781" "unprognostic (1.30e-1)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (4.89e-3)" "unprognostic (4.94e-2)" "unprognostic (2.63e-2)" "unprognostic (2.58e-2)" "unprognostic (3.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.14e-3)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (4.71e-3)" 75.5 16.8 14.4 8.1 14.6 2.5 64.4 14.7 22.0 24.9 13.7 23.5 6.7 26.8 10.9 10.9 33.5 15.5 48.3 14.1 14.7 34.9 12.1 39.8 7.8 14.9 14.6 56.7 8.8 4.4 9.3 85.9 15.3 15.8 6.4 1.5 9.1 17.9 15.4 11.4 16.1 16.7 15.1 39.0 16.0 3.3 16.1 19.0 29.1 18.6 3.5 27.9 18.4 14.9 0.2 34.2 67.2 31.0 51.2 40.0 0.0 34.8 67.7 19.0 26.7 0.1 2.9 0.0 219.9 17.5 79.9 0.5 0.5 3.2 23.8 0.2 2.0 11.0 35.9 0.0 81.8 0.0 0.1 13.4 0.1 61.0 6.0 78.7 349.6 0.0 0.1 0.2 85.9 0.0 0.1 0.1 5.8 0.0 10.4 32.5 7.6 0.1 41.3 0.0 0.1 67.2 0.0 0.2 221.8 8.6 144.4 2.4 201.1 93.4 10.4 68.3 3.9 0.0 0.2 0.7 187.1 0.0 81.8 20.5 0.7 0.3 0.1 0.1 0.2 2.3 0.0 0.0 1.0 2.0 0.2 0.0 9.8 0.0 0.1 3.7 0.1 50.2 14.4 14.6 14.7 22.0 14.1 14.7 14.9 14.6 15.3 15.1 16.1 14.9 1903.6 12.8 27.3 1.3 20.6 83.6 11.8 3.1 5.7 0.7 15.2 26.8 94.8 11.5 3.1 187.6 0.0 2.3 15.4 0.1 74.3 135.7 5.9 124.1 94.6 1236.2 0.0 40.6 0.0 5.7 12.9 207.3 0.5 236.4 2.5 12.7 994.2 11.1 17.0 0.0 0.0 0.3 18.3 55.9 89.5 17.0 82.3 481.1 188.5 26.2 49.6 9.2 41.2 0.5 0.2 4.3 0.0 86.9 8.0 11.0 0.0 12.9 1.7 4.7 151.2 115.5 165.0 1.9 7.6 2.7 65.8 23.8 15.9 109.9 0.0 4.5 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPATCH11 "CCDC75, CENP-Y, CENPY, FLJ38348" ENSG00000152133 "G-patch domain containing 11" Q8N954 2 37084451-37099244 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038231, HPA038232" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA038231: AB_2675904, HPA038232: AB_10675788" "unprognostic (1.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.45e-1)" "unprognostic (1.80e-1)" "unprognostic (3.88e-2)" "unprognostic (2.23e-2)" "unprognostic (4.58e-3)" "unprognostic (2.40e-2)" "unprognostic (2.44e-2)" "unprognostic (4.39e-2)" "unprognostic (1.16e-1)" "unprognostic (1.26e-1)" "unprognostic (8.64e-3)" "unprognostic (4.31e-2)" "unprognostic (4.44e-2)" "unprognostic (3.40e-2)" "unprognostic (7.16e-2)" 23.0 6.3 7.5 7.8 8.5 10.0 6.9 8.8 9.9 7.0 6.0 4.5 4.8 4.8 3.7 5.1 3.7 4.4 5.4 7.7 8.8 5.5 5.7 6.3 12.7 8.3 8.0 5.9 3.0 5.5 3.5 5.7 8.5 4.0 4.9 21.0 3.7 4.1 2.4 5.9 5.0 4.3 8.5 8.0 4.8 11.6 8.0 10.3 6.4 5.4 11.7 5.2 3.1 10.4 12.5 7.4 12.4 9.7 25.7 11.9 13.2 22.1 8.9 13.1 10.7 9.4 5.2 14.4 12.1 8.3 11.4 8.8 14.8 5.3 19.5 24.7 16.1 26.3 9.8 9.6 8.3 31.7 27.5 7.8 9.4 18.0 10.1 8.6 11.6 9.0 25.0 65.8 15.4 6.3 20.6 17.4 5.3 20.5 10.3 16.9 26.4 40.7 5.7 5.3 14.9 13.9 11.6 7.4 11.2 9.9 7.6 14.6 12.9 23.7 13.1 17.4 24.7 25.6 28.2 21.6 16.9 26.2 21.3 5.9 2.4 2.2 4.4 2.0 4.4 8.7 3.2 3.7 3.6 6.8 3.4 3.5 0.8 6.7 0.7 12.2 2.6 1.5 7.5 8.5 8.8 9.9 7.7 8.8 8.3 8.0 8.5 8.5 8.0 10.4 14.7 12.8 8.1 3.9 23.3 4.2 2.7 5.7 7.4 24.3 6.2 7.0 14.1 8.6 5.0 11.0 25.0 8.8 48.7 12.1 11.7 9.3 32.9 12.6 20.0 12.8 3.0 22.1 14.3 14.1 30.5 12.2 8.6 13.9 12.0 8.7 17.9 15.0 13.4 13.5 12.1 9.1 6.1 18.8 15.0 10.5 16.1 21.1 3.6 5.6 12.7 28.9 22.6 10.6 12.5 14.8 4.9 22.2 23.2 1.6 9.7 13.2 11.5 52.7 13.1 13.4 21.7 75.5 43.6 7.8 5.4 3.8 16.8 13.7 6.0 2.0 GPBAR1 "BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5" ENSG00000179921 "G protein-coupled bile acid receptor 1" Q8TDU6 2 218259496-218263861 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.9;breast: 17.8;gallbladder: 17.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 20.3;Enteroendocrine cells: 46.0;Hofbauer cells: 16.3;Kupffer cells: 50.6;Macrophages: 19.9;monocytes: 45.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "classical monocyte: 288.1;intermediate monocyte: 712.0;non-classical monocyte: 695.6" "Lineage enriched" "Detected in many" 5 "monocytes: 712.0" "Cell line enhanced" "Detected in some" "ASC diff: 1.1;HHSteC: 1.7;U-937: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA062890 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA062890: AB_2684896" "unprognostic (8.47e-2)" "unprognostic (3.72e-3)" "unprognostic (1.88e-2)" "unprognostic (9.49e-2)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-1)" "unprognostic (2.63e-1)" "unprognostic (8.76e-3)" "unprognostic (4.32e-2)" "unprognostic (4.64e-2)" "unprognostic (1.55e-1)" "unprognostic (7.40e-7)" "unprognostic (4.18e-2)" "unprognostic (4.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" 31.9 1.6 0.1 2.7 0.2 2.2 17.8 0.4 0.7 0.6 0.2 3.8 1.0 0.9 0.0 0.5 1.2 17.3 5.1 0.2 0.1 5.3 1.9 2.2 0.8 0.1 0.1 1.8 1.7 0.0 0.8 3.9 0.1 1.1 0.5 0.0 0.8 0.3 0.5 1.4 4.9 10.1 0.1 7.5 6.4 2.4 0.3 0.4 1.7 0.7 0.2 4.8 0.8 0.1 0.1 0.0 0.1 0.0 1.1 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 1.7 0.1 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.9 0.8 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 1.9 0.1 0.6 288.1 0.4 0.7 712.0 0.7 0.2 0.5 0.7 140.2 0.7 0.6 0.4 6.5 0.5 695.6 6.0 0.9 156.5 0.1 0.2 0.4 0.7 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 6.2 0.0 3.4 0.0 1.1 0.3 0.2 0.2 0.0 0.0 0.1 0.3 0.5 1.5 0.1 3.7 0.0 0.5 1.8 0.2 11.7 0.2 8.2 1.0 20.3 1.5 46.0 0.0 0.0 0.5 4.5 2.8 6.6 0.8 1.3 6.2 1.8 0.0 16.3 0.0 0.0 2.7 0.0 50.6 1.2 1.9 3.4 19.9 0.0 1.9 45.3 0.0 0.0 0.0 0.0 0.5 1.5 2.6 0.3 0.3 0.4 0.2 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.1 0.4 1.6 0.8 0.1 0.2 0.4 GPD1 ENSG00000167588 "Glycerol-3-phosphate dehydrogenase 1" P21695 12 50103982-50111313 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 609.9;skeletal muscle: 577.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 99.1;Proximal enterocytes: 247.0;Proximal tubular cells: 298.4" "Cancer enhanced" "Detected in many" "liver cancer: 18.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 134.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044620, HPA058621" Enhanced NA NA 4700000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044620: AB_10796803, HPA058621: " "unprognostic (2.65e-2)" "unprognostic (5.60e-2)" "unprognostic (3.28e-2)" "unprognostic (3.37e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (1.45e-3)" "unprognostic (7.19e-2)" "unprognostic (9.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (1.37e-1)" "unprognostic (9.58e-2)" "unprognostic (3.37e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" 609.9 4.7 9.1 1.6 16.8 0.2 229.2 22.7 12.8 0.3 5.5 6.4 76.4 0.2 5.3 4.9 0.5 16.6 9.2 10.1 14.2 149.3 147.6 18.4 1.0 32.6 18.3 0.3 7.2 13.0 1.3 0.0 26.5 1.3 3.3 1.0 33.0 1.3 577.1 10.2 76.9 1.3 32.7 0.4 3.3 0.8 18.4 1.5 2.7 215.7 0.4 4.1 1.0 49.4 0.1 0.2 0.1 0.1 134.0 0.0 0.3 0.1 0.0 0.0 0.0 27.0 0.1 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.1 0.6 25.2 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.7 0.7 0.3 0.0 0.2 0.1 0.4 0.1 3.7 0.0 0.2 0.2 30.2 0.2 0.0 0.6 0.2 0.0 1.5 1.0 0.0 1.8 0.0 0.0 0.0 0.3 0.2 0.1 0.6 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 16.8 22.7 12.8 10.1 14.2 32.6 18.3 26.5 32.7 18.4 49.4 3.4 3.2 3.2 0.0 2.4 0.0 0.2 0.3 0.6 3.2 3.4 3.7 5.8 11.5 1.8 5.5 8.4 0.0 0.0 3.0 43.0 0.9 0.1 0.5 0.1 0.2 1.2 5.3 0.2 0.7 0.0 0.8 4.1 0.2 0.0 0.1 1.1 99.1 2.3 3.3 0.2 9.7 0.0 1.0 0.4 0.0 0.0 5.2 1.8 0.0 1.0 2.8 0.0 0.0 4.0 0.6 8.0 0.0 0.0 0.1 247.0 298.4 0.4 1.7 0.0 7.0 1.1 0.0 0.0 0.8 0.4 0.0 1.2 0.0 10.6 0.2 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 GPR153 PGR1 ENSG00000158292 "G protein-coupled receptor 153" Q6NV75 1 6247353-6261098 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Hepatocytes: 33.2;Horizontal cells: 63.9;Intestinal goblet cells: 52.5;Urothelial cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.1;PC-3: 68.6;RH-30: 32.2;SCLC-21H: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007159 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA007159: AB_1849268" "unprognostic (1.02e-2)" "unprognostic (2.40e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (5.74e-3)" "unprognostic (3.33e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (8.54e-2)" "unprognostic (1.02e-2)" "unprognostic (1.31e-1)" "unprognostic (1.51e-2)" "unprognostic (1.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" 13.2 2.0 17.8 2.9 8.4 0.3 10.4 0.7 11.3 12.2 0.2 9.9 4.0 9.3 11.3 7.8 8.7 3.8 9.4 7.9 9.7 2.9 7.1 10.5 1.8 4.7 11.8 8.9 1.5 5.5 12.0 6.9 2.9 6.4 5.2 3.2 3.1 3.3 1.8 9.2 21.9 4.8 3.6 6.9 3.5 2.2 28.3 1.4 1.9 1.4 1.4 6.9 7.9 3.2 6.1 1.0 14.4 17.4 26.1 10.3 1.2 4.0 3.6 1.5 1.7 2.5 2.4 0.0 6.0 4.2 3.3 7.8 0.8 17.2 0.6 4.0 3.5 0.1 2.4 0.5 5.1 0.6 2.3 6.3 4.5 1.1 0.9 2.7 1.2 5.3 0.9 0.0 5.0 6.7 2.0 4.7 1.1 3.5 68.6 7.5 32.2 0.4 0.6 3.4 32.7 11.8 2.7 10.0 8.4 3.9 3.9 3.2 3.5 3.5 3.3 0.5 1.8 0.3 0.3 1.4 1.6 8.0 1.4 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 17.8 8.4 0.7 11.3 7.9 9.7 4.7 11.8 2.9 3.6 28.3 3.2 0.7 0.0 0.0 0.3 0.1 3.4 1.8 8.9 1.2 6.2 1.3 2.2 6.2 4.3 5.5 0.0 0.0 0.2 5.9 3.3 0.0 0.2 1.2 0.6 8.5 1.6 3.5 2.7 1.7 0.0 0.3 9.9 1.1 0.4 1.3 0.7 0.7 33.2 1.1 63.9 3.0 52.5 6.1 1.0 3.7 2.5 4.7 1.5 5.4 1.0 2.2 2.7 3.1 6.6 0.1 0.6 9.2 7.5 1.3 1.6 9.6 2.0 1.7 1.6 0.0 9.6 4.7 0.1 1.7 1.1 7.4 0.4 1.2 1.3 2.0 17.2 GPR180 ITR ENSG00000152749 "G protein-coupled receptor 180" Q86V85 13 94601857-94634661 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047250 Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047250: AB_2679998" "unprognostic (3.91e-3)" "unprognostic (3.28e-1)" "unprognostic (4.16e-3)" "unprognostic (2.95e-1)" "unprognostic (1.17e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (6.71e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (2.49e-2)" "unprognostic (1.10e-1)" "unprognostic (8.47e-2)" "unprognostic (2.80e-2)" 5.8 2.3 3.0 2.4 3.6 0.9 2.6 4.5 4.5 2.7 4.1 2.1 2.0 2.4 1.8 1.7 2.5 1.8 1.8 3.4 3.2 2.5 6.9 2.4 2.4 2.8 3.0 2.4 3.1 2.5 3.5 3.6 3.1 2.5 2.5 7.0 2.8 2.3 1.8 1.9 1.6 2.8 3.6 2.2 2.7 1.1 3.2 2.6 3.6 1.8 2.6 2.3 1.5 3.6 14.6 3.6 5.1 5.4 10.5 11.4 2.1 9.7 7.7 9.3 12.3 4.4 9.8 4.8 4.1 8.4 6.4 9.0 7.3 6.9 12.7 12.7 4.6 9.4 4.9 0.0 8.3 13.6 7.3 6.5 5.8 5.7 7.7 8.3 9.6 6.8 2.7 2.3 9.3 2.1 6.9 3.0 3.3 10.4 4.0 7.8 6.8 2.0 10.4 4.3 7.4 5.3 4.5 9.9 12.2 6.4 7.0 5.5 8.7 5.7 4.6 6.8 8.2 3.8 4.2 2.2 9.5 10.9 7.9 0.1 0.5 0.1 0.8 0.3 1.4 0.5 0.9 0.6 0.9 0.5 1.1 0.9 0.0 0.5 0.4 0.6 1.2 0.4 3.0 3.6 4.5 4.5 3.4 3.2 2.8 3.0 3.1 3.6 3.2 3.6 9.0 3.2 4.1 20.2 6.1 6.0 5.4 11.2 7.4 12.5 7.4 5.5 6.8 7.2 7.8 12.9 31.3 8.7 9.3 3.8 5.9 8.3 1.0 11.1 8.9 8.3 10.3 3.6 47.6 10.2 27.8 11.8 9.7 9.0 5.1 9.2 9.7 30.8 10.5 18.5 30.5 9.8 6.1 4.4 4.9 0.7 9.6 5.3 7.2 18.7 4.1 15.4 9.2 40.7 26.3 9.6 3.7 5.7 16.0 10.6 3.0 7.5 16.8 22.0 6.6 6.3 10.6 3.5 10.6 6.4 4.7 4.1 6.6 3.6 5.5 5.0 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Cell type enhanced" "Detected in some" "Adipocytes: 26.7;Endothelial cells: 26.4;Hepatic stellate cells: 24.7;Sertoli cells: 6.6;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 18.7;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 40.6 6.9 7.0 3.3 6.2 0.5 22.1 6.0 8.8 4.9 6.2 4.2 0.9 7.4 0.7 2.6 6.0 3.3 23.8 5.6 5.9 24.6 3.6 28.6 0.9 8.0 7.5 3.5 3.7 1.4 5.9 4.0 8.6 5.8 0.7 0.9 2.9 0.9 5.7 2.9 5.1 2.5 6.5 4.1 5.6 1.7 10.7 0.5 18.2 2.5 0.6 7.0 4.9 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.7 1.1 0.0 0.1 0.0 2.0 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.8 0.0 0.0 0.3 0.3 0.0 18.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 31.3 0.1 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 6.2 6.0 8.8 5.6 5.9 8.0 7.5 8.6 6.5 10.7 6.3 26.7 0.0 0.5 0.7 0.1 2.4 0.2 0.0 1.2 0.1 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.3 26.4 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.2 0.0 0.0 24.7 0.1 0.3 0.0 0.2 0.0 0.0 1.2 1.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 6.6 0.6 16.8 0.0 0.2 0.1 1.3 0.0 0.1 0.3 0.0 0.3 GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 179.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.9;Hepatocytes: 237.3;Paneth cells: 88.4;Proximal enterocytes: 139.7;Proximal tubular cells: 164.9" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;Karpas-707: 2.8;U-266/70: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favorable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" 22.6 2.4 2.2 4.6 1.9 2.3 12.5 3.3 4.7 0.7 3.5 36.0 18.3 0.5 0.4 2.4 1.3 2.4 40.3 2.1 0.4 13.9 179.6 0.4 0.3 0.8 0.5 1.1 10.3 1.4 2.9 0.1 0.6 1.8 5.8 0.6 14.6 1.2 50.1 17.1 18.0 0.4 0.2 0.6 15.0 2.6 0.9 0.0 0.9 24.3 0.2 0.6 1.3 0.9 0.2 0.8 0.2 0.5 0.4 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.9 0.4 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.7 1.3 0.3 1.5 2.5 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.2 2.8 0.0 1.3 0.4 0.4 0.3 0.6 0.5 0.5 0.1 1.5 0.0 0.9 0.5 0.8 0.2 0.7 0.1 0.1 1.9 0.1 0.2 0.1 0.6 0.7 0.1 2.9 0.2 0.2 0.4 0.9 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.2 1.9 3.3 4.7 2.1 0.4 0.8 0.5 0.6 0.2 0.9 0.9 0.2 0.0 0.0 14.4 5.3 1.7 1.3 1.2 0.6 0.9 14.1 4.6 8.5 34.3 1.8 7.3 0.0 0.0 0.4 176.9 21.5 1.1 16.5 0.5 0.4 1.1 2.4 43.2 0.8 2.4 3.3 0.3 51.0 0.7 8.9 0.3 14.3 237.3 0.1 3.3 0.5 30.4 0.0 14.4 2.1 48.1 0.6 1.2 1.8 1.0 0.1 15.6 0.0 2.0 0.0 1.3 88.4 0.4 0.1 1.2 139.7 164.9 0.5 2.0 0.0 2.0 0.4 1.0 0.6 2.4 4.5 0.0 1.8 0.4 62.1 1.6 GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884362-46931289 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 267.4;skeletal muscle: 176.4;tongue: 184.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Hepatocytes: 123.9;Syncytiotrophoblasts: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 159.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA051514: AB_2681516" "unprognostic (1.65e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.95e-3)" "unprognostic (3.44e-2)" "unprognostic (6.12e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.44e-2)" "unprognostic (4.86e-1)" "unprognostic (3.54e-3)" "unprognostic (3.18e-1)" 56.8 10.4 51.6 4.0 49.9 3.8 17.0 49.1 56.9 5.2 38.4 7.7 1.7 3.7 31.4 77.8 7.6 9.8 7.9 51.3 45.7 23.5 103.7 2.1 4.3 69.8 45.9 2.3 267.4 8.3 13.0 3.1 63.9 24.2 4.9 6.9 48.8 10.9 176.4 37.8 3.9 3.1 60.2 2.3 58.6 15.0 54.9 7.7 7.6 184.5 13.4 2.7 7.7 64.5 42.6 19.0 23.8 90.6 32.7 7.0 43.1 28.9 10.9 30.7 19.2 65.3 17.6 29.9 24.7 20.7 15.6 33.6 43.3 42.8 20.4 14.0 21.1 10.5 10.8 159.9 22.4 75.6 9.5 15.2 37.0 30.0 46.3 20.3 15.1 56.1 8.7 23.3 10.3 75.8 15.1 62.9 25.3 52.2 54.2 0.3 26.3 71.1 12.4 21.0 73.7 37.7 14.9 76.4 39.0 9.4 19.6 67.6 11.3 21.1 40.9 14.2 23.4 110.2 36.9 87.1 32.6 48.3 11.7 0.4 0.2 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 51.6 49.9 49.1 56.9 51.3 45.7 69.8 45.9 63.9 60.2 54.9 64.5 1.3 6.4 3.4 54.9 4.8 15.9 4.9 6.8 64.3 14.5 6.7 8.4 14.9 8.6 9.1 18.4 22.9 9.2 0.3 10.2 11.7 7.0 9.6 12.2 7.2 2.3 13.1 5.2 16.7 30.2 44.8 7.5 37.2 37.5 3.8 14.9 5.0 123.9 3.8 6.7 18.8 13.4 6.1 3.2 7.3 22.9 4.7 2.3 8.8 1.0 1.1 42.5 1.0 13.6 26.0 25.6 5.2 15.4 7.9 12.4 2.0 38.6 5.4 5.9 0.0 5.2 3.6 2.5 17.3 53.1 16.3 83.3 1.4 2.6 6.3 4.2 GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103926-1106791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 18580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749" "unprognostic (8.42e-3)" "prognostic favorable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favorable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favorable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 927.8 535.3 415.1 127.4 428.7 178.0 733.3 440.7 519.1 280.8 478.7 249.0 259.0 188.4 318.9 220.4 199.2 196.6 426.0 419.2 450.3 536.5 687.8 307.9 216.4 430.9 448.3 260.3 157.9 285.5 398.4 147.2 454.1 322.1 110.9 167.5 304.9 193.8 672.3 290.4 236.2 87.9 418.2 213.2 219.0 1403.5 444.0 158.7 291.5 399.7 182.5 319.0 245.2 429.1 258.1 286.8 405.8 863.0 1202.1 706.0 449.3 199.3 713.5 371.1 375.9 590.5 339.8 92.8 211.8 405.8 313.5 283.1 239.7 289.3 180.5 522.3 436.5 175.0 246.9 849.2 697.4 207.6 269.4 707.3 432.1 188.3 314.7 665.9 527.1 317.5 249.4 225.7 311.1 660.4 353.8 354.9 386.2 569.7 458.9 482.8 55.3 271.3 408.9 629.9 348.3 220.6 390.5 366.1 422.1 246.7 358.1 498.0 450.9 392.3 257.4 680.6 254.6 786.5 582.0 224.3 369.4 412.2 230.9 578.9 539.6 564.4 219.8 405.4 256.9 352.7 319.7 230.7 404.0 309.9 339.4 245.0 265.1 196.6 462.2 278.8 310.3 841.7 415.1 428.7 440.7 519.1 419.2 450.3 430.9 448.3 454.1 418.2 444.0 429.1 415.9 179.5 189.7 21.2 281.7 510.0 525.8 1188.1 512.2 332.2 845.1 868.2 264.6 316.0 600.6 472.6 98.0 562.5 231.3 479.1 1592.6 515.8 4209.7 546.8 326.3 268.7 397.1 215.0 24.5 368.7 1327.3 536.1 99.9 442.3 346.1 242.6 322.0 826.2 1184.1 208.6 33.1 328.7 671.4 583.1 1304.8 18580.2 384.9 735.2 677.7 21.5 1786.8 502.6 192.6 13.6 35.4 484.0 507.9 312.9 189.2 694.7 1861.9 3024.7 800.9 246.0 243.3 244.6 587.1 1310.8 202.4 357.7 467.0 978.1 281.0 186.7 336.4 662.6 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Microglial cells: 56.2;Sertoli cells: 59.2;Smooth muscle cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;HUVEC TERT2: 24.9;OE19: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 38.4 18.0 4.2 5.9 5.0 2.7 24.6 5.0 4.6 18.8 3.5 26.3 10.0 21.1 3.5 12.6 19.6 5.7 48.8 4.0 5.1 14.2 12.9 65.6 7.8 3.9 3.6 35.0 4.7 21.3 13.3 8.3 3.9 14.1 4.9 1.0 7.8 4.0 11.9 11.5 25.8 7.3 3.3 37.0 27.5 4.1 4.9 6.2 19.6 9.7 6.8 19.4 18.1 3.5 3.7 2.3 5.4 5.7 11.8 11.0 1.6 7.1 32.1 4.1 2.3 1.7 5.4 3.9 1.6 11.1 7.5 0.9 2.3 7.7 2.7 15.4 2.0 0.7 4.6 7.0 8.2 0.2 2.0 1.5 1.1 8.5 1.2 5.2 24.9 2.4 0.4 3.7 1.5 0.7 3.8 3.5 0.8 25.8 5.2 1.3 0.8 0.9 0.6 1.5 1.8 4.9 2.4 1.1 7.0 3.0 0.1 0.9 7.8 2.3 1.6 14.6 2.8 0.9 4.4 2.4 4.9 4.4 2.4 0.4 1.5 2.9 2.0 1.4 0.1 3.8 3.0 1.6 0.9 4.0 4.5 2.0 2.1 0.1 0.5 0.0 4.0 1.7 4.2 5.0 5.0 4.6 4.0 5.1 3.9 3.6 3.9 3.3 4.9 3.5 32.6 57.7 3.7 3.6 19.7 1.7 0.7 0.5 1.2 3.9 2.3 2.0 19.4 0.0 1.3 3.7 0.0 3.7 13.3 0.4 0.0 1.1 18.7 0.4 5.1 28.4 4.8 0.0 17.7 3.1 15.8 35.7 18.8 1.0 4.5 7.8 24.7 2.2 4.4 1.7 36.5 0.8 6.1 15.5 6.3 4.9 4.4 14.2 7.2 56.2 3.6 0.0 19.6 14.1 5.7 2.4 1.2 4.5 10.2 0.7 4.9 0.6 0.8 0.9 59.2 18.2 46.5 1.3 2.1 0.7 2.4 13.1 14.1 4.6 0.5 0.9 GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.1;Distal tubular cells: 41.1;Extravillous trophoblasts: 26.5;Hofbauer cells: 39.9;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.0;myeloid DC: 5.9;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019306: , HPA011326: AB_1847629" "unprognostic (1.08e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" "unprognostic (6.36e-3)" "unprognostic (6.70e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-3)" "unprognostic (1.48e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" 13.5 7.8 16.4 2.9 16.7 0.5 7.6 13.3 18.0 17.3 9.2 6.4 7.7 24.8 15.3 3.6 14.3 8.5 9.7 18.1 15.0 13.3 4.5 4.4 5.8 19.4 18.7 16.9 2.6 7.3 7.0 35.0 16.1 7.5 2.4 6.3 3.1 21.1 7.8 3.0 26.8 15.1 16.5 1.8 3.9 12.9 14.1 5.8 14.5 5.2 3.8 15.0 10.1 26.6 31.4 21.7 9.6 41.2 51.4 28.6 16.4 24.1 63.6 24.5 34.3 22.9 1.1 0.5 20.6 66.4 81.7 20.5 5.8 105.4 42.8 0.1 2.1 0.8 39.3 48.0 43.0 0.1 1.5 31.3 75.3 43.5 103.1 73.0 42.3 13.8 3.0 5.2 55.3 0.4 1.9 0.8 10.2 0.1 15.7 0.2 33.6 0.0 74.5 21.9 0.4 60.0 36.5 0.6 42.3 24.3 2.2 2.8 27.9 23.1 39.7 31.6 29.2 2.4 0.6 15.5 69.8 0.1 5.8 0.0 1.9 0.0 0.0 0.2 0.0 9.0 0.1 0.0 5.9 8.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 16.4 16.7 13.3 18.0 18.1 15.0 19.4 18.7 16.1 16.5 14.1 26.6 1.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.0 0.0 0.6 5.5 0.0 168.1 0.0 0.0 41.1 1.9 0.0 0.7 16.9 1.3 0.0 0.0 0.0 0.9 26.5 4.3 0.0 1.0 0.0 4.8 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 8.8 1.5 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 104.7 0.7 0.9 0.0 0.0 GUCD1 "C22orf13, LLN4, MGC1842" ENSG00000138867 "Guanylyl cyclase domain containing 1" Q96NT3 22 24540423-24555935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 161.3;Proximal enterocytes: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022786 Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA022786: AB_1845711" "unprognostic (1.58e-1)" "prognostic favorable (6.84e-4)" "unprognostic (2.83e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (1.61e-1)" "unprognostic (3.96e-2)" "unprognostic (1.89e-1)" "prognostic favorable (7.26e-4)" "unprognostic (1.28e-1)" "unprognostic (3.55e-2)" "unprognostic (1.76e-2)" "unprognostic (4.36e-2)" "unprognostic (8.63e-2)" "unprognostic (1.59e-1)" "unprognostic (3.01e-2)" 36.9 27.5 19.3 25.3 22.0 89.9 29.2 20.5 18.9 19.6 17.7 37.5 67.5 19.1 16.7 25.2 21.1 25.4 62.0 17.0 19.8 43.0 93.9 34.3 34.6 23.4 23.4 19.4 37.1 24.1 12.3 21.6 21.3 31.0 36.2 10.9 25.0 20.2 96.4 27.6 59.6 23.1 22.1 30.4 37.1 18.8 23.1 27.9 16.6 117.6 36.9 26.8 19.8 22.2 40.8 37.1 30.9 38.5 62.5 58.4 25.7 38.7 59.5 63.3 61.0 56.9 30.2 72.1 26.0 50.9 39.3 51.2 35.2 43.3 33.6 74.2 45.4 31.3 36.1 51.3 50.6 83.2 63.2 59.6 33.9 64.0 29.0 38.7 67.5 35.9 32.3 75.6 48.4 47.2 49.2 34.1 31.0 95.3 30.6 57.2 52.0 73.1 49.8 44.9 33.8 33.2 47.2 60.6 33.3 23.6 49.6 56.7 48.7 143.4 59.8 44.5 34.6 70.1 53.8 50.8 57.9 45.3 49.9 20.2 14.9 52.5 7.4 14.8 8.5 37.0 7.1 7.7 13.7 42.6 6.7 7.6 15.2 7.5 14.5 9.7 7.6 13.8 19.3 22.0 20.5 18.9 17.0 19.8 23.4 23.4 21.3 22.1 23.1 22.2 20.5 16.0 33.9 6.8 41.5 12.4 11.8 13.9 21.1 5.3 25.9 18.3 51.2 78.6 13.3 5.5 6.2 18.6 21.2 99.7 52.8 27.1 15.8 13.4 13.6 16.4 19.8 86.1 2.3 66.0 20.1 17.5 35.7 17.9 15.2 19.5 18.5 161.3 27.1 3.3 3.0 52.3 16.2 23.5 12.0 8.6 19.0 21.0 17.8 2.8 28.6 18.2 18.6 5.5 7.5 48.1 72.4 16.1 17.5 32.1 149.6 84.9 9.7 13.2 26.3 12.4 16.7 24.3 32.0 18.7 11.1 16.3 14.6 28.9 36.7 18.9 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 156.3" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Enteroendocrine cells: 20.4;Granulosa cells: 10.2;Hepatocytes: 20.2" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.1;CACO-2: 30.4;Hep G2: 32.6;NTERA-2: 38.4;SK-MEL-30: 87.6;SuSa: 59.0" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: AB_2685323" "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favorable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 156.3 2.2 10.3 1.9 10.8 0.2 38.9 18.4 8.8 3.0 8.5 3.9 1.5 6.6 1.0 0.9 5.1 2.2 1.4 11.2 18.9 2.0 18.5 0.5 0.6 29.4 24.5 2.5 5.4 1.0 0.8 2.1 27.3 4.0 2.8 1.4 4.7 6.6 0.3 1.9 2.1 3.7 36.0 0.3 4.5 0.9 13.7 0.4 1.7 0.5 0.3 3.7 2.0 35.4 0.1 11.5 39.1 0.2 20.5 0.0 28.5 2.0 6.3 6.1 8.2 30.4 0.6 0.0 3.1 5.2 6.6 0.0 22.5 0.5 6.8 0.2 6.3 0.1 0.7 32.6 6.7 0.0 8.9 8.1 0.4 1.0 0.0 0.2 0.0 0.0 0.3 0.1 6.6 1.9 0.0 1.0 38.4 0.4 0.2 6.1 13.0 0.0 0.0 0.1 0.0 0.7 0.1 0.3 87.6 59.0 4.1 25.4 0.0 0.0 6.7 3.8 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.3 10.8 18.4 8.8 11.2 18.9 29.4 24.5 27.3 36.0 13.7 35.4 0.3 0.0 0.0 10.7 0.2 0.4 1.1 0.5 0.0 1.2 2.1 0.8 1.2 4.3 0.2 0.0 4.2 6.0 0.0 1.2 5.9 1.0 0.4 3.8 1.0 0.3 20.4 0.0 5.9 4.0 7.9 1.6 4.6 0.7 0.0 10.2 0.0 20.2 1.1 0.0 4.9 1.7 0.0 1.0 0.0 0.5 0.6 0.1 3.6 0.0 0.0 1.6 0.0 0.5 0.1 2.1 0.6 3.0 0.0 1.0 0.4 2.4 1.1 0.1 0.0 0.3 1.2 0.3 1.5 0.0 0.3 2.3 0.0 3.2 3.5 0.7 GYS1 "GSY, GYS" ENSG00000104812 "Glycogen synthase 1" P13807 19 48968130-48993310 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 118.5;skeletal muscle: 319.4;tongue: 201.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007793, HPA041598" Enhanced Approved Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "CAB007793: AB_562291, HPA041598: AB_2677571" "unprognostic (3.37e-1)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (6.83e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (3.30e-2)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.46e-4)" "unprognostic (4.04e-2)" "unprognostic (6.76e-2)" "unprognostic (5.87e-3)" "unprognostic (3.81e-2)" 32.4 26.3 17.9 16.2 18.8 46.0 23.7 26.4 23.3 17.1 22.2 21.7 15.3 18.8 8.9 38.2 18.7 10.1 118.5 19.7 17.6 21.8 14.9 16.0 15.5 22.2 20.9 19.7 13.6 15.7 15.5 11.3 19.6 27.4 14.7 19.2 22.2 15.5 319.4 20.7 19.9 16.7 16.4 18.5 23.2 6.1 20.2 14.7 15.9 201.6 14.4 24.3 23.2 18.3 67.3 26.3 19.0 26.3 43.2 16.9 37.6 45.5 31.7 46.8 54.3 25.8 21.3 28.0 27.0 44.7 12.4 46.6 32.0 57.7 40.6 17.4 46.5 23.1 33.3 23.1 24.3 25.4 15.9 41.8 27.2 30.2 25.4 40.5 39.8 28.8 16.4 36.1 59.4 25.4 31.8 21.9 10.2 29.0 29.8 26.6 33.2 27.5 46.7 70.6 11.8 16.4 40.5 52.1 10.4 25.2 27.7 26.1 31.0 57.1 22.0 26.1 50.5 29.8 33.1 13.5 58.3 22.2 13.1 7.7 9.4 6.6 7.0 5.3 8.6 5.2 6.0 6.5 13.4 3.9 4.7 4.4 3.7 10.6 8.0 7.2 8.6 7.1 17.9 18.8 26.4 23.3 19.7 17.6 22.2 20.9 19.6 16.4 20.2 18.3 3.5 0.0 14.2 21.9 5.9 5.1 3.7 11.7 11.4 4.2 7.3 5.5 67.9 2.8 5.8 0.0 16.7 7.6 6.8 13.2 0.0 8.1 0.3 6.9 8.9 7.1 7.2 4.8 14.7 6.9 31.7 5.0 12.8 11.9 4.5 6.7 9.7 5.2 8.3 0.0 16.6 9.2 4.1 7.0 5.7 0.7 5.3 7.2 7.2 4.7 9.8 3.3 10.3 8.5 6.9 11.8 8.2 5.7 9.7 5.4 9.2 6.0 6.2 11.7 0.0 5.0 7.3 1.3 2.9 15.3 4.1 4.0 5.2 3.8 11.7 3.3 GYS2 ENSG00000111713 "Glycogen synthase 2" P54840 12 21536107-21604847 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "liver: 173.8" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 63.6" "Cancer enriched" "Detected in single" 29 "liver cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039482 Approved NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "HPA039482: AB_10795107" "unprognostic (7.22e-3)" "unprognostic (2.85e-2)" "unprognostic (8.88e-2)" "unprognostic (1.78e-2)" "unprognostic (5.68e-2)" "unprognostic (3.16e-1)" "prognostic favorable (7.62e-5)" "unprognostic (1.06e-1)" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (4.68e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (4.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.85e-1)" "unprognostic (2.66e-4)" 3.1 0.0 0.1 0.0 0.0 0.0 1.0 0.1 0.1 2.4 0.0 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.2 0.0 0.0 0.2 173.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.4 63.6 0.0 0.0 7.7 0.0 6.1 1.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 5.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 13 "dendritic cells: 385.8;NK-cells: 810.5;T-cells: 243.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.7;HMC-1: 2.1;JURKAT: 3.5;MOLT-4: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 2.2 1.1 0.9 10.0 0.9 21.6 1.1 3.6 2.0 1.4 0.3 1.5 2.1 0.8 0.2 0.8 1.3 1.8 0.8 0.9 0.9 1.0 3.3 5.3 19.2 1.0 0.8 0.7 0.4 0.0 0.9 0.4 1.0 1.3 0.3 0.2 2.8 0.4 0.7 0.8 6.2 0.2 0.7 22.7 3.7 1.8 0.9 8.7 1.6 0.1 3.8 1.5 1.4 1.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.1 0.0 0.4 1.3 0.6 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.1 0.5 0.1 0.3 0.1 9.1 1.4 1.3 583.9 1.7 366.5 0.9 189.2 471.3 1.5 4.0 182.8 379.2 11.9 194.9 2.3 3.6 99.1 227.5 0.9 0.9 3.6 2.0 0.9 0.9 1.0 0.8 1.0 0.7 0.9 1.0 3.4 0.0 0.0 0.3 5.7 3.1 0.1 0.0 0.6 0.5 2.4 2.2 0.1 1.5 0.0 0.0 0.0 0.2 385.8 0.1 0.0 0.4 0.9 0.6 1.5 1.4 0.0 12.0 0.3 0.4 0.4 2.2 13.3 1.1 0.0 0.1 3.6 1.4 0.2 0.0 0.2 0.4 0.0 3.7 4.7 1.6 0.0 5.9 1.8 1.0 8.6 1.6 810.5 0.5 0.3 0.3 0.0 0.0 35.8 0.1 0.0 1.2 0.0 1.4 0.0 1.5 1.2 0.5 1.1 0.9 1.4 0.5 243.6 0.2 0.1 0.1 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827157 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 378.7;Proximal tubular cells: 501.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved NA NA 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA043041: AB_2678284, HPA061143: AB_2684439" "unprognostic (3.11e-1)" "prognostic favorable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favorable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favorable (5.19e-4)" 41.2 109.0 81.5 20.2 84.2 82.1 35.1 82.7 103.9 22.8 78.9 53.7 45.3 24.6 31.1 29.0 28.5 21.9 138.6 89.9 83.8 100.1 236.2 39.2 24.6 82.8 80.2 22.0 63.5 54.0 72.7 23.1 83.7 33.5 23.3 32.2 32.5 37.7 198.8 31.2 44.8 24.7 80.1 35.2 52.9 91.7 84.0 35.8 35.1 156.2 18.4 34.8 24.6 87.6 31.1 46.1 40.9 46.5 35.1 13.8 37.0 38.1 35.2 57.7 46.1 23.7 26.5 6.4 76.5 32.9 39.6 33.2 39.1 38.2 17.2 64.5 63.4 12.0 47.9 69.3 50.2 15.7 62.6 16.9 80.6 28.8 19.6 50.6 50.1 79.8 16.1 56.3 18.3 51.2 41.1 34.0 15.7 32.0 42.3 34.2 25.8 73.6 74.5 13.8 54.7 47.4 41.8 52.9 84.9 30.8 38.7 52.0 38.7 17.5 21.5 36.9 44.6 63.3 64.7 19.8 29.8 14.5 28.5 37.3 33.3 64.9 26.0 59.1 19.0 31.3 34.0 27.3 30.7 30.4 32.0 27.4 29.7 25.5 88.2 64.8 42.8 30.3 81.5 84.2 82.7 103.9 89.9 83.8 82.8 80.2 83.7 80.1 84.0 87.6 46.2 9.6 39.0 11.8 33.7 23.8 45.1 59.7 12.0 117.1 39.5 31.1 84.2 65.8 39.7 46.0 64.6 52.4 43.2 60.9 158.5 45.6 193.1 75.0 12.1 35.3 39.6 378.7 24.6 38.3 38.5 25.6 23.9 35.5 30.4 36.0 41.0 186.9 76.2 138.0 22.2 41.2 93.6 49.0 41.6 60.1 46.9 47.6 55.2 12.2 50.1 95.2 64.9 7.1 19.7 49.7 68.8 54.9 50.4 48.3 168.9 501.7 70.2 117.0 72.3 33.3 61.1 245.2 68.3 29.1 45.6 68.7 44.1 45.3 39.9 49.9 HAVCR2 "CD366, FLJ14428, Tim-3, TIM3, TIMD3" ENSG00000135077 "Hepatitis A virus cellular receptor 2" Q8TDQ0 5 157085832-157142869 "CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.1" "Cell type enhanced" "Detected in many" "dendritic cells: 87.6;granulocytes: 80.6;Hofbauer cells: 148.3;Kupffer cells: 89.1;Langerhans cells: 67.8;Macrophages: 83.2;monocytes: 49.5;NK-cells: 70.0;Proximal tubular cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 53.8;intermediate monocyte: 57.9;myeloid DC: 137.9;NK-cell: 97.1;non-classical monocyte: 36.1" "Group enriched" "Detected in all" 6 "dendritic cells: 137.9;monocytes: 57.9;NK-cells: 97.1" "Cell line enhanced" "Detected in some" "ASC diff: 7.8;Daudi: 6.4;HDLM-2: 26.3;HMC-1: 6.0;RPMI-8226: 21.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB026003 Enhanced NA NA 9900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026003: " "unprognostic (2.50e-2)" "unprognostic (1.11e-2)" "unprognostic (5.18e-2)" "unprognostic (2.04e-3)" "unprognostic (3.79e-2)" "unprognostic (1.14e-1)" "unprognostic (6.69e-2)" "unprognostic (2.54e-1)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (8.48e-2)" "unprognostic (5.13e-2)" "unprognostic (7.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.34e-1)" 14.2 8.2 9.5 19.7 11.1 13.9 5.3 11.1 13.3 4.9 10.4 5.4 4.0 3.2 6.0 3.7 3.3 12.8 2.5 9.1 11.8 26.8 9.8 22.6 32.1 18.0 13.7 1.7 3.0 2.8 1.8 16.9 16.9 2.1 6.8 1.2 2.9 2.9 1.7 2.2 4.9 7.9 16.1 24.1 4.7 2.0 17.5 9.1 1.6 2.1 14.0 13.1 1.2 27.2 0.0 0.2 0.1 0.2 7.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 6.4 0.3 0.0 0.2 0.1 0.0 0.0 0.0 26.3 0.0 1.1 0.1 0.0 0.0 0.0 6.0 0.4 0.4 0.0 0.2 0.0 0.0 0.7 0.1 2.3 0.0 0.1 0.1 3.9 0.2 0.0 0.0 0.1 3.0 21.5 0.3 0.0 0.2 0.1 0.0 0.1 0.2 0.5 0.2 0.3 0.0 0.9 0.3 0.3 0.0 0.3 1.8 0.2 0.1 0.7 0.1 16.7 53.8 0.1 14.6 57.9 3.0 1.2 5.9 7.9 137.9 0.5 7.0 9.5 2.5 97.1 36.1 16.4 11.5 43.1 9.5 11.1 11.1 13.3 9.1 11.8 18.0 13.7 16.9 16.1 17.5 27.2 1.2 6.4 6.5 2.0 5.9 1.0 0.2 0.1 0.0 0.9 0.7 1.5 1.1 0.0 1.9 0.0 0.0 0.6 87.6 0.3 7.9 0.1 11.1 0.1 0.1 3.7 0.0 1.3 2.1 0.0 0.8 0.9 0.5 0.1 80.6 0.1 1.1 0.5 148.3 0.0 1.7 0.3 0.0 89.1 67.8 7.8 0.3 83.2 3.6 31.9 49.5 0.1 70.0 1.0 4.8 0.1 0.1 0.0 16.3 0.5 0.1 57.7 0.0 0.2 6.6 0.7 0.5 0.3 0.4 0.1 1.3 1.1 26.3 1.5 0.2 0.3 HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;skin 1: 30.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 84.7;Basal respiratory cells: 52.0;Basal squamous epithelial cells: 120.1;Ionocytes: 87.5;Langerhans cells: 124.0;Suprabasal keratinocytes: 106.1" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 5.9" "Immune cell enriched" "Detected in many" 5 "neutrophil: 176.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 176.7" "Cell line enriched" "Detected in some" 6 "HaCaT: 118.4" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" 22.2 0.3 0.1 9.8 0.2 22.1 7.6 0.1 5.9 8.9 0.2 0.7 0.9 0.2 0.3 40.8 0.7 0.8 0.9 0.3 0.1 3.9 2.9 11.9 0.6 0.1 0.1 0.1 0.2 5.5 0.3 4.5 1.2 3.4 0.3 0.2 14.2 14.7 0.2 30.2 1.0 0.3 0.1 25.9 1.5 2.7 0.2 10.5 0.5 1.9 10.2 6.9 14.0 0.1 4.5 0.4 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 118.4 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.1 3.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 19.5 0.2 0.0 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 38.7 2.5 2.6 0.0 5.3 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 176.7 0.0 23.9 0.0 0.0 1.4 0.1 0.2 0.1 5.9 0.3 0.1 0.1 0.1 1.2 0.1 0.2 0.1 0.4 0.0 4.3 0.0 0.5 94.4 84.7 52.0 120.1 0.5 3.4 1.1 0.1 0.0 40.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 24.9 0.4 0.2 1.2 0.0 0.0 0.0 0.0 26.3 2.4 0.0 0.3 2.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 87.5 4.1 124.0 2.7 0.0 17.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 8.5 0.1 0.0 0.1 1.4 0.0 0.1 47.2 106.1 2.6 1.5 0.0 0.0 32.5 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HEBP2 "C6orf34, SOUL" ENSG00000051620 "Heme binding protein 2" Q9Y5Z4 6 138403531-138422197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 678.8;Urothelial cells: 1174.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 219.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016928 Approved NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA016928: AB_1850572" "unprognostic (8.53e-2)" "unprognostic (1.54e-1)" "unprognostic (7.92e-2)" "unprognostic (6.88e-2)" "unprognostic (7.96e-2)" "unprognostic (1.48e-1)" "unprognostic (5.60e-2)" "unprognostic (1.62e-2)" "unprognostic (1.50e-1)" "unprognostic (2.48e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.47e-5)" "unprognostic (2.76e-3)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "prognostic favorable (3.07e-4)" 168.1 34.4 13.9 15.0 11.2 31.8 147.3 13.8 13.8 50.6 14.8 51.7 21.9 35.2 28.0 131.1 30.4 12.8 78.5 11.2 15.8 42.4 72.3 26.4 7.0 14.1 17.4 27.8 37.2 14.6 27.2 13.3 14.8 52.7 19.2 10.1 72.2 10.5 132.8 80.4 32.7 13.3 13.4 17.6 54.3 7.5 22.9 8.6 27.0 33.5 12.3 51.5 81.5 12.5 42.8 8.6 13.6 45.4 42.5 17.1 88.2 45.7 12.8 6.0 9.9 23.2 28.3 1.3 74.0 24.0 29.0 40.0 13.2 22.7 3.4 31.0 60.8 17.4 8.7 42.9 24.8 27.4 0.1 20.8 25.8 6.5 22.6 32.2 23.7 31.5 40.7 23.4 10.5 34.9 9.0 83.7 17.7 22.2 33.1 29.1 20.5 26.1 26.5 31.8 31.0 5.7 47.5 85.5 29.4 21.0 27.6 219.5 28.9 14.5 40.8 18.7 46.1 36.5 31.5 17.2 25.2 41.6 9.4 5.6 7.9 5.6 1.5 8.2 2.0 5.0 4.3 2.5 7.4 2.9 2.0 1.7 14.6 1.9 5.0 4.6 6.4 2.3 13.9 11.2 13.8 13.8 11.2 15.8 14.1 17.4 14.8 13.4 22.9 12.5 106.3 19.2 31.6 5.9 48.7 117.5 387.1 73.4 71.7 28.6 274.7 262.4 160.8 190.1 98.1 121.4 14.6 273.3 49.2 231.9 295.4 304.3 4.5 167.0 104.2 91.7 102.2 38.3 1.1 578.1 408.5 70.7 72.9 229.9 45.1 38.4 74.6 547.6 93.6 18.5 1.0 169.4 79.3 84.7 58.5 10.9 67.7 70.9 58.7 8.4 98.3 90.5 51.5 3.5 1.8 678.8 224.6 66.5 68.2 510.0 115.2 353.0 72.7 38.9 59.2 78.4 89.0 11.7 58.2 201.2 204.9 291.3 59.9 29.2 141.8 1174.8 HEPACAM "FLJ25530, GLIALCAM" ENSG00000165478 "Hepatic and glial cell adhesion molecule" Q14CZ8 11 124919205-124936412 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell cycle, Growth arrest, Growth regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 222.6;choroid plexus: 79.7" "Group enriched" "Detected in some" 9 "Astrocytes: 184.8;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 163.2" "Cancer enriched" "Detected in some" 12 "glioma: 29.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "Hep G2: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017613, CAB025486" Enhanced Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB025486: , HPA017613: AB_1850595" "unprognostic (3.22e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-1)" "unprognostic (6.41e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.33e-2)" "unprognostic (1.06e-6)" "unprognostic (2.62e-1)" "unprognostic (3.21e-1)" 15.6 0.3 172.8 0.2 203.3 0.0 2.5 170.4 162.1 0.2 79.7 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.2 163.2 156.1 0.1 16.2 0.0 0.2 222.6 182.8 0.0 0.0 0.0 0.8 0.0 183.6 0.2 0.2 1.8 0.2 0.5 0.1 0.0 0.2 0.1 205.7 0.0 0.1 0.2 182.0 0.0 0.0 0.3 0.6 0.0 0.1 212.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.2 172.8 203.3 170.4 162.1 163.2 156.1 222.6 182.8 183.6 205.7 182.0 212.2 0.1 0.0 0.0 184.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.6 0.0 15.5 0.0 72.9 163.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 HEYL "bHLHb33, HESR3, HEY3" ENSG00000163909 "Hes related family bHLH transcription factor with YRPW motif like" Q9NQ87 1 39623435-39639643 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 69.5" "Cell type enhanced" "Detected in many" "Late spermatids: 17.5;Leydig cells: 26.1;Peritubular cells: 56.8;Sertoli cells: 52.6;Skeletal myocytes: 33.4;Smooth muscle cells: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 8.0;LHCN-M2: 20.8;RH-30: 26.5;THP-1: 6.2;U-266/84: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001438, HPA076960" Approved Approved Mitochondria,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA001438: AB_1079052, HPA076960: AB_2732326" "unprognostic (1.98e-2)" "unprognostic (7.92e-2)" "unprognostic (4.19e-3)" "unprognostic (3.49e-1)" "unprognostic (2.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (7.20e-2)" "unprognostic (5.92e-2)" "unprognostic (1.19e-2)" "unprognostic (2.35e-1)" "unprognostic (8.50e-2)" "prognostic unfavorable (2.26e-6)" "prognostic unfavorable (3.57e-4)" "unprognostic (2.67e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.63e-5)" 17.9 12.4 9.5 5.6 12.0 0.1 9.3 10.5 6.9 18.5 4.1 7.2 1.9 27.9 5.7 4.8 17.4 8.0 57.0 5.4 15.0 9.5 4.2 23.5 1.7 11.3 15.6 13.4 69.5 2.4 15.3 29.5 12.9 17.0 3.4 6.7 2.7 14.4 6.0 2.9 4.9 25.0 7.3 6.3 6.0 16.0 17.1 1.3 20.4 5.4 2.0 8.7 11.3 8.3 0.0 2.8 4.8 0.0 0.0 0.5 0.3 0.0 0.1 0.0 0.1 2.0 0.3 0.0 1.6 0.5 0.0 0.0 2.8 0.0 0.3 0.0 3.2 5.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 8.0 0.5 0.7 20.8 1.9 0.0 0.1 0.0 0.2 0.1 1.4 26.5 0.2 0.0 0.5 0.6 0.0 0.0 0.1 0.0 1.1 0.0 6.2 0.0 0.0 0.2 0.0 0.0 0.7 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 12.0 10.5 6.9 5.4 15.0 11.3 15.6 12.9 7.3 17.1 8.3 1.3 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.9 0.1 0.0 3.6 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 1.0 5.4 1.3 4.0 1.9 0.0 0.0 0.1 3.5 0.3 13.3 2.0 2.4 0.0 0.7 1.4 0.0 0.3 1.7 0.2 0.2 0.0 0.0 2.3 17.5 26.1 0.4 5.4 4.7 0.1 0.4 0.0 0.0 2.4 2.8 0.3 56.8 0.0 0.2 0.0 0.1 0.0 3.9 52.6 33.4 29.5 0.4 2.0 0.1 0.1 0.3 0.3 1.9 0.4 0.2 HOGA1 "C10orf65, DHDPS2, DHDPSL, FLJ37472, NPL2" ENSG00000241935 "4-hydroxy-2-oxoglutarate aldolase 1" Q86XE5 10 97584323-97612802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 51.8;liver: 54.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 35.8;Distal tubular cells: 29.4;Hepatocytes: 43.3;Late spermatids: 18.4;Proximal tubular cells: 98.0" "Group enriched" "Detected in many" 5 "liver cancer: 4.5;renal cancer: 9.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AN3-CA: 7.8;EFO-21: 9.7;Hep G2: 26.1;RPTEC TERT1: 31.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039466 Approved NA NA 16000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039466: AB_2676522" "unprognostic (6.44e-2)" "unprognostic (3.64e-2)" "unprognostic (7.50e-2)" "unprognostic (2.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.29e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-3)" "unprognostic (4.72e-1)" "unprognostic (2.37e-1)" "unprognostic (1.28e-1)" "unprognostic (6.80e-2)" "prognostic favorable (9.08e-4)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (2.94e-3)" "unprognostic (7.20e-4)" 4.1 8.3 5.8 0.2 7.4 0.4 1.9 9.3 5.0 0.7 11.4 0.2 0.3 1.1 3.7 1.0 2.0 2.5 21.1 4.4 6.5 51.8 54.8 1.4 0.3 8.2 9.2 0.2 15.3 5.7 3.6 0.1 8.3 1.1 0.1 0.8 1.7 2.1 3.4 1.5 0.3 0.5 7.3 0.4 0.2 0.9 7.9 0.3 1.8 12.1 0.2 0.4 0.9 10.3 0.3 3.7 0.1 7.8 1.5 0.3 0.1 0.1 0.2 0.0 0.0 3.0 0.2 0.3 9.7 0.2 0.5 2.6 0.0 0.2 0.1 0.1 4.0 0.1 1.4 26.1 1.1 0.2 0.1 0.3 0.7 0.1 0.1 1.9 0.4 0.1 0.0 0.4 0.6 1.6 0.1 0.1 0.2 0.2 0.0 0.1 0.6 0.4 31.5 0.6 0.6 1.0 0.1 1.3 0.5 0.2 2.8 0.0 0.2 0.8 0.2 0.3 0.2 0.5 0.9 0.1 2.0 0.1 0.1 0.6 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.1 0.4 0.2 0.2 1.0 0.2 0.2 0.3 0.2 0.1 5.8 7.4 9.3 5.0 4.4 6.5 8.2 9.2 8.3 7.3 7.9 10.3 0.0 0.0 0.0 7.2 1.5 0.1 0.7 0.5 1.8 0.4 0.1 0.4 6.0 35.8 0.2 9.2 0.0 0.1 0.0 0.1 29.4 5.9 3.8 1.8 0.1 0.0 0.0 0.0 1.3 0.2 0.0 0.2 0.0 0.5 0.0 0.1 0.4 43.3 0.1 1.7 1.2 0.0 0.0 1.3 0.0 18.4 0.0 0.8 1.8 1.0 0.0 2.0 0.0 1.5 12.3 0.5 0.1 0.0 0.0 0.1 0.0 98.0 3.2 0.3 0.0 4.5 0.9 0.0 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.2 HOXA10 "HOX1, HOX1H" ENSG00000253293 "Homeobox A10" P31260 7 27170592-27180261 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 76.8;skeletal muscle: 76.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 174.0;Enteroendocrine cells: 68.1;Paneth cells: 32.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basophil: 10.7;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 10.7;NK-cells: 13.1" "Cell line enhanced" "Detected in many" "HEK 293: 179.0;THP-1: 96.7;U-937: 100.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 190 "spinal cord: 18.9" "CAB019384, HPA071918" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Nuclear bodies" "CAB019384: , HPA071918: " "unprognostic (4.98e-2)" "unprognostic (5.66e-2)" "unprognostic (1.93e-1)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (2.73e-3)" "unprognostic (2.61e-2)" "unprognostic (1.41e-2)" "unprognostic (8.05e-2)" "unprognostic (2.71e-2)" "unprognostic (3.83e-3)" "unprognostic (1.57e-1)" "unprognostic (7.13e-2)" "unprognostic (8.46e-3)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-2)" 13.4 6.8 0.0 6.1 0.0 4.3 6.8 0.0 0.0 40.8 0.0 32.6 0.1 76.8 9.1 0.2 8.3 0.1 0.0 0.0 0.0 13.7 0.1 0.1 2.3 0.0 0.0 0.8 0.0 0.0 0.0 13.4 0.0 26.3 13.2 0.0 0.0 15.4 76.4 6.0 7.9 44.9 0.1 0.2 0.1 0.3 0.0 5.2 0.1 0.0 0.2 20.4 17.2 0.1 20.6 4.3 0.0 59.9 29.3 28.0 0.2 40.1 27.2 18.0 16.8 6.1 17.8 0.0 10.9 31.6 0.0 22.6 15.5 0.0 13.2 9.5 179.0 21.6 15.0 0.5 0.8 9.6 31.4 17.8 0.9 1.5 0.0 0.0 27.5 6.3 0.9 0.0 13.3 0.0 0.0 63.1 0.0 16.6 18.8 1.9 4.0 0.1 34.7 9.6 46.7 0.1 13.8 0.0 0.1 6.4 0.1 96.7 0.0 0.0 16.1 21.1 0.2 0.4 0.1 0.0 0.0 100.4 0.5 10.7 0.1 0.3 2.2 0.0 0.0 0.1 0.0 0.2 1.2 0.3 0.0 0.0 0.0 13.1 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 5.5 0.0 0.0 0.0 0.2 3.7 10.0 0.0 0.6 0.0 4.4 4.6 1.6 0.0 0.0 7.3 0.0 0.5 4.5 28.8 19.6 0.0 0.0 3.1 174.0 5.4 68.1 15.5 0.0 0.0 0.4 13.3 0.0 2.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 25.0 0.0 2.5 4.7 0.0 0.0 2.0 5.4 0.0 0.5 0.0 7.2 0.0 0.0 0.0 32.1 0.4 1.3 18.1 18.8 27.1 0.0 0.0 0.0 13.3 15.7 2.3 4.6 0.5 4.1 0.5 3.1 0.0 25.5 10.1 HOXB8 "HOX2, HOX2D" ENSG00000120068 "Homeobox B8" P17481 17 48611377-48615292 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.1;epididymis: 48.1;kidney: 37.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 88.3;Distal tubular cells: 72.4;Endometrial ciliated cells: 21.3;Enteroendocrine cells: 44.1;Glandular and luminal cells: 26.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 33.3" "Region enhanced" "Detected in many" "spinal cord: 114.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.0;HDLM-2: 17.2;HEK 293: 36.9;LHCN-M2: 17.3;RPTEC TERT1: 35.3" "Region enriched" "Detected in single" 65 "pons and medulla: 6.5" "Region enriched" "Detected in all" 5 "spinal cord: 51.2" HPA075905 Supported Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA075905: AB_2686767" "unprognostic (4.44e-1)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (1.94e-2)" "unprognostic (9.07e-5)" "unprognostic (6.63e-3)" "unprognostic (1.40e-3)" "unprognostic (6.00e-2)" "unprognostic (5.66e-3)" "unprognostic (2.93e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.30e-7)" "unprognostic (1.77e-2)" "unprognostic (6.64e-2)" "unprognostic (4.57e-2)" "unprognostic (2.88e-3)" 7.2 7.2 0.1 1.5 0.0 0.0 2.7 0.0 0.0 10.7 0.0 4.7 0.0 2.8 48.1 0.0 1.4 0.0 0.0 0.0 0.0 37.6 0.0 0.4 0.0 36.4 0.0 0.1 0.1 0.8 0.1 0.3 1.8 1.0 1.2 0.0 0.0 20.8 0.4 0.5 7.1 1.5 114.1 0.1 6.6 1.0 0.0 0.0 0.1 0.0 0.0 3.7 0.7 20.8 2.1 5.3 0.0 0.8 0.7 1.0 0.8 0.0 0.0 0.0 0.0 0.3 0.8 0.0 34.0 5.3 0.6 0.0 0.1 0.0 0.0 17.2 36.9 1.0 0.1 0.0 0.3 0.0 5.5 1.1 0.0 0.1 0.0 0.7 2.1 0.2 11.6 0.0 17.3 0.0 0.0 0.4 0.0 11.3 0.0 0.0 3.6 0.1 35.3 1.0 0.0 0.1 0.6 0.0 5.4 0.1 0.4 0.0 8.8 0.0 1.6 0.1 0.7 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 36.4 0.0 1.8 114.1 0.0 20.8 4.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 88.3 0.0 0.0 0.1 1.8 72.4 0.0 0.3 21.3 2.1 2.6 44.1 0.0 0.0 0.0 0.8 0.3 0.0 26.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.2 0.0 0.0 0.7 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.2 2.7 8.9 0.0 0.0 0.0 0.1 0.8 2.3 9.2 0.0 0.0 0.0 0.3 0.0 5.0 0.0 HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 181.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 214.8;Early spermatids: 153.9;Granulosa cells: 187.2;Late spermatids: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA042890: AB_2678216, HPA050453: AB_2681131" "unprognostic (3.17e-3)" "unprognostic (1.62e-2)" "unprognostic (1.90e-3)" "prognostic favorable (9.23e-6)" "unprognostic (3.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.82e-1)" "prognostic favorable (9.29e-7)" "unprognostic (1.44e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (7.35e-2)" 76.3 63.6 28.1 13.3 30.1 11.6 22.8 25.1 29.5 23.3 27.6 31.7 38.9 22.8 11.5 29.8 21.2 19.0 89.9 24.8 33.1 69.0 149.0 28.7 13.9 25.4 33.2 50.8 20.0 21.8 8.8 16.8 27.1 20.3 26.9 12.6 18.8 15.9 151.7 31.1 32.2 20.5 26.6 18.6 24.6 14.0 32.0 19.6 30.4 181.3 15.8 29.2 15.0 28.5 45.0 39.4 29.0 14.8 49.0 48.4 33.4 30.1 18.6 21.1 17.7 77.0 49.4 28.5 16.2 44.4 26.9 50.6 31.9 42.2 25.8 120.9 21.0 30.0 58.5 76.1 30.7 17.1 18.5 52.0 29.9 31.3 22.8 30.5 24.8 34.7 42.3 18.9 58.2 29.6 42.5 15.3 17.2 106.9 50.3 27.1 87.4 42.7 44.5 40.4 20.7 14.5 75.8 49.5 26.0 23.7 70.0 20.0 28.3 30.2 27.9 85.2 29.6 21.5 57.3 13.5 37.0 24.8 18.2 54.3 8.4 32.8 4.6 8.1 6.8 6.9 4.8 5.0 9.5 8.4 5.6 5.9 48.0 5.9 11.5 9.4 8.7 4.9 28.1 30.1 25.1 29.5 24.8 33.1 25.4 33.2 27.1 26.6 32.0 28.5 32.0 99.3 84.3 48.6 14.1 13.3 17.5 21.6 29.6 9.3 12.0 13.3 214.8 14.3 32.2 14.7 6.2 26.5 18.3 23.7 64.6 15.5 153.9 38.6 38.3 19.1 14.9 32.8 10.8 18.7 30.9 31.1 29.0 27.8 30.4 187.2 17.2 124.2 35.7 6.7 12.2 32.2 8.2 23.6 12.5 163.0 27.4 27.5 8.8 15.9 47.3 24.1 6.2 16.1 19.3 13.2 23.5 47.0 20.9 16.0 52.4 111.1 37.7 14.5 46.0 18.1 46.9 12.9 16.4 34.2 16.2 31.7 16.2 108.9 36.2 29.5 HSPB7 cvHSP ENSG00000173641 "Heat shock protein family B (small) member 7" Q9UBY9 1 16014028-16019594 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 4135.3;skeletal muscle: 2417.8;tongue: 1229.5" "Cell type enriched" "Detected in some" 32 "Cardiomyocytes: 2389.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "fHDF/TERT166: 315.1" "Not detected" "Not detected" HPA027639 Approved Approved Nucleoplasm NA NA 130000 "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA027639: AB_10601756" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.28e-3)" "unprognostic (7.44e-3)" "unprognostic (8.35e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (1.02e-1)" "unprognostic (5.32e-2)" "unprognostic (2.47e-3)" "unprognostic (3.19e-3)" "unprognostic (6.94e-2)" "unprognostic (1.55e-1)" "unprognostic (1.20e-2)" "unprognostic (1.18e-2)" "unprognostic (1.51e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (1.26e-4)" 306.8 123.4 3.9 32.1 4.4 0.2 119.7 8.8 5.1 49.6 8.6 138.3 5.1 179.5 7.5 44.2 64.8 18.7 4135.3 4.1 5.6 38.5 3.2 22.1 1.7 13.1 7.9 25.4 9.2 38.8 5.3 7.1 12.0 43.0 8.0 3.1 35.1 24.4 2417.8 19.3 34.0 189.2 5.3 4.5 71.4 20.2 4.7 0.6 14.1 1229.5 0.7 99.2 30.5 6.7 0.0 0.0 0.0 1.5 70.7 3.2 1.8 18.4 1.1 0.0 0.2 0.0 0.1 0.0 0.0 315.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 3.4 0.0 0.0 2.1 0.0 0.0 0.0 7.9 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.6 0.1 0.1 0.0 0.1 5.3 3.3 0.0 0.0 0.0 1.3 0.0 11.8 0.0 1.3 0.1 1.1 0.0 14.1 0.6 1.9 0.0 10.3 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.4 8.8 5.1 4.1 5.6 13.1 7.9 12.0 5.3 4.7 6.7 0.5 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.8 0.2 0.4 2389.7 0.0 0.0 3.7 0.0 2.8 0.0 0.0 13.7 1.4 55.5 0.1 0.7 26.6 0.0 0.0 0.0 0.2 1.4 46.3 0.0 0.1 0.0 0.4 0.0 0.0 1.6 1.7 0.1 0.0 0.0 0.0 4.6 74.2 14.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.2 0.0 0.0 6.8 0.0 0.5 0.0 0.2 0.0 0.6 0.0 20.2 42.6 1.9 0.9 0.1 2.6 3.3 0.5 3.0 0.0 0.1 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116698 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3792.9;Distal enterocytes: 2150.5;Endothelial cells: 1972.1;Exocrine glandular cells: 1603.8;Intestinal goblet cells: 1638.8;Pancreatic endocrine cells: 1678.1;Paneth cells: 2179.2;Proximal enterocytes: 3048.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;T-cells: 2.6" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 2026.8;BJ hTERT+ SV40 Large T+ RasG12V: 1782.5;EFO-21: 547.7;Karpas-707: 501.5;SK-MEL-30: 607.2" HPA028875 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" 470.3 323.3 178.3 115.7 177.4 162.8 410.3 180.9 232.6 351.4 162.7 374.4 129.2 137.8 39.9 310.4 163.2 344.1 471.5 174.5 182.4 217.9 150.4 608.2 48.3 203.8 187.7 75.6 39.3 30.3 65.3 183.8 215.0 85.0 221.4 6.1 156.9 47.0 113.1 129.8 256.2 117.4 194.9 797.8 697.0 140.2 194.1 202.8 149.8 152.4 54.2 116.9 213.7 190.8 181.3 0.4 1.3 0.4 0.5 21.7 1.7 2.8 8.8 2026.8 1782.5 3.8 146.8 1.5 547.7 115.3 33.8 5.7 1.1 0.2 79.7 2.1 3.7 1.0 1.4 0.9 13.7 0.6 1.1 2.0 2.0 353.8 0.1 1.1 284.0 1.3 1.1 501.5 0.1 0.5 1.7 1.1 0.5 0.5 24.7 1.8 0.5 0.6 1.2 0.6 0.4 1.1 0.0 0.1 607.2 1.4 0.9 3.0 0.3 0.2 2.7 325.8 1.0 9.4 14.6 3.9 0.9 0.5 1.4 0.0 1.3 0.5 0.3 7.0 0.3 0.0 2.6 0.7 0.8 0.1 0.0 0.4 0.0 0.4 2.1 0.1 2.5 2.1 178.3 177.4 180.9 232.6 174.5 182.4 203.8 187.7 215.0 194.9 194.1 190.8 3792.9 391.0 82.7 1.3 26.8 171.2 6.5 126.9 91.6 4.9 23.4 38.2 45.9 151.5 237.4 12.9 8.4 7.3 14.9 2150.5 1.9 50.6 13.6 1035.5 188.3 1972.1 267.8 42.3 0.6 1603.8 221.2 330.8 892.5 838.5 45.1 1174.4 742.5 5.8 158.3 5.0 0.4 1638.8 107.8 106.9 163.5 36.7 172.1 59.6 350.4 84.3 26.1 8.3 0.0 0.0 0.7 1678.1 2179.2 417.5 6.3 11.1 3048.1 23.7 548.1 20.5 276.1 45.2 295.8 20.3 12.1 151.9 140.4 5.2 34.1 302.4 523.4 80.4 IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 155.9;Kupffer cells: 205.4;Langerhans cells: 139.3;Macrophages: 426.2;monocytes: 144.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Cell line enhanced" "Detected in many" "Daudi: 655.7;RPMI-8226: 717.7;SK-BR-3: 457.4;U-266/84: 794.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" 132.4 121.0 18.4 708.3 20.8 283.8 58.6 20.3 104.5 40.8 48.7 129.0 197.3 22.2 26.9 38.7 57.3 109.6 31.2 18.0 23.3 80.3 148.2 572.7 370.7 32.0 24.9 14.8 61.3 75.0 27.9 128.8 40.5 31.6 148.0 2.6 66.3 22.0 12.6 55.0 153.6 165.0 26.8 385.3 112.2 16.0 69.4 91.9 54.2 9.0 221.0 215.7 19.6 49.8 115.5 59.2 0.4 37.9 11.2 19.9 102.6 11.8 17.2 34.6 91.8 132.3 193.1 655.7 96.6 39.7 175.2 85.1 69.9 30.1 3.7 182.5 55.2 8.1 98.1 188.9 111.8 20.1 46.9 70.4 60.4 59.8 19.7 4.4 2.0 23.8 96.8 394.8 16.6 217.3 9.9 2.5 21.2 380.6 68.7 65.8 4.5 717.7 101.1 3.7 5.3 8.0 200.5 457.4 11.3 7.4 31.6 8.8 4.2 55.2 34.2 120.7 12.0 14.6 794.7 368.5 154.1 133.5 8.5 106.9 9509.8 3890.4 40.8 14243.6 38.8 952.6 28.5 31.1 5699.9 708.1 19.7 24.3 2102.8 70.2 9865.9 173.2 41.5 11082.7 18.4 20.8 20.3 104.5 18.0 23.3 32.0 24.9 40.5 26.8 69.4 49.8 6.4 9.6 38.8 0.0 54.2 3.6 2.5 2.1 2.2 0.4 8.6 13.2 1.1 4.3 18.3 12.9 0.0 5.6 4.0 8.3 1.9 1.8 0.3 2.5 1.7 8.4 0.0 4.6 0.1 1.1 14.8 8.1 6.6 4.1 13.9 0.2 3.6 1.3 155.9 0.0 0.1 14.9 2.0 205.4 139.3 0.2 0.3 426.2 5.4 1.0 144.1 0.7 5.2 0.0 0.1 1.2 3.4 0.0 47.7 4.6 5.9 5.4 8.9 0.7 0.0 2.6 1.8 0.2 0.7 3.7 3.3 12.0 9.6 1.5 9.6 1.2 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 580.8;Fibroblasts: 1360.5;Leydig cells: 1030.8;Peritubular cells: 1495.9;Sertoli cells: 1170.1;Smooth muscle cells: 420.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 1163.6;BJ: 476.9;BJ hTERT+: 683.3;fHDF/TERT166: 1045.9;hTERT-RPE1: 468.5;U-87 MG: 631.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 145.8 90.2 28.1 9.2 32.6 0.4 150.5 31.8 40.8 276.6 71.6 75.5 20.8 117.2 129.5 75.8 237.4 36.8 107.0 28.4 33.1 30.6 7.7 40.4 8.7 32.7 29.2 136.8 15.9 4.8 106.3 15.7 33.2 129.3 28.0 6.6 35.9 122.2 38.5 39.2 52.5 39.0 36.7 45.2 67.6 22.2 41.7 6.8 58.4 102.2 9.2 127.1 214.1 27.2 135.3 219.6 0.2 177.3 313.9 1163.6 0.8 476.9 683.3 126.9 69.0 23.2 294.7 0.0 68.5 1045.9 96.4 453.3 3.0 42.3 26.2 1.2 2.8 4.4 37.1 33.3 111.9 0.8 1.1 325.5 2.3 57.4 11.9 468.5 30.5 7.5 0.6 9.3 53.1 0.5 6.6 1.0 6.8 4.1 150.4 2.3 4.9 5.6 10.1 3.3 1.3 8.7 152.2 0.0 10.9 4.0 6.3 0.5 132.2 87.2 41.2 95.5 18.0 5.3 10.7 0.6 631.6 6.7 49.5 0.0 0.0 31.6 0.6 6.8 3.4 0.1 1.0 5.4 2.1 0.0 0.5 6.8 0.0 0.0 20.1 0.0 0.0 1.5 28.1 32.6 31.8 40.8 28.4 33.1 32.7 29.2 33.2 36.7 41.7 27.2 83.9 6.4 4.2 2.0 3.4 113.6 41.0 580.8 23.9 2.5 5.9 29.0 21.1 10.0 37.6 20.2 0.0 3.0 3.5 0.2 11.7 87.9 9.6 4.9 99.2 71.9 0.0 3.2 3.1 8.0 4.9 1360.5 30.5 2.5 0.0 2.3 116.4 0.8 7.6 0.0 3.6 0.3 50.8 6.8 122.8 32.6 1030.8 15.2 144.1 19.7 2.5 51.1 0.0 1.5 0.9 77.1 0.0 1495.9 9.6 94.9 0.0 15.2 13.9 2.8 1170.1 102.3 420.9 3.8 6.8 8.0 87.8 3.4 14.1 0.4 0.0 34.1 IGHA1 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 7411.2;lymphoid tissue: 6397.6;salivary gland: 8904.9;stomach 1: 6664.9" "Group enriched" "Detected in many" 10 "B-cells: 17763.5;Plasma cells: 34095.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2571.8;naive B-cell: 1114.6" "Lineage enriched" "Detected in many" 284 "B-cells: 2571.8" "Cell line enhanced" "Detected in many" "HDLM-2: 17.4;RPMI-8226: 34.7;SH-SY5Y: 22.3;U-266/70: 78.2;U-266/84: 24.0" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 130000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" 200.6 41.7 1.4 1121.1 1.0 918.5 953.5 0.7 6.5 214.3 4.2 5973.6 7411.2 79.9 3.5 641.9 203.5 662.9 73.8 0.6 1.3 278.5 327.7 1305.3 1420.6 3.5 1.1 40.6 115.1 3.5 38.3 6.7 1.1 202.5 1338.5 0.0 8904.9 69.0 10.8 56.7 3788.8 69.5 1.4 6397.6 6664.9 23.2 1.0 131.0 447.3 0.4 1949.0 1616.2 302.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.8 0.0 0.0 3.6 0.0 0.0 0.0 17.4 0.0 3.7 0.0 0.0 0.0 5.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 4.1 14.4 5.5 0.0 0.0 3.8 4.3 34.7 0.0 0.0 9.7 22.3 2.6 0.0 0.0 0.0 0.0 1.6 5.1 0.0 3.9 4.2 3.2 78.2 24.0 2.2 0.0 2.4 0.0 3.8 3.0 0.6 1.3 0.3 1.0 2571.8 0.7 1.1 1.5 1114.6 0.4 1.0 9.0 0.9 0.9 1.7 1.0 508.3 1.4 1.0 0.7 6.5 0.6 1.3 3.5 1.1 1.1 1.4 1.0 1.9 11.8 131.4 783.5 0.0 17763.5 0.0 26.0 0.0 1.2 0.0 22.4 4.6 4.7 22.8 46.4 0.0 0.0 0.7 55.5 20.8 0.0 0.0 0.0 0.1 0.1 26.5 28.4 167.0 0.0 0.0 0.5 56.5 99.4 0.1 584.8 0.0 353.8 225.1 1.6 0.0 0.0 13.6 0.0 57.8 0.0 0.0 0.0 34.6 0.0 0.0 6.7 0.0 11.3 0.0 0.0 0.0 12.8 0.0 34095.8 33.2 0.0 1.4 16.0 0.0 0.0 2.0 13.6 0.0 0.0 0.8 0.0 6.0 2514.2 0.0 27.9 1.2 IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5017.7;salivary gland: 3728.4" "Group enriched" "Detected in many" 22 "B-cells: 3713.4;Plasma cells: 10918.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 876 "memory B-cell: 279.6;naive B-cell: 123.8" "Lineage enriched" "Detected in single" 1214 "B-cells: 279.6" "Group enriched" "Detected in some" 42 "U-266/70: 181.9;U-266/84: 63.9" "Not detected" "Not detected" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 67000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" 24.3 3.7 0.0 14.2 0.0 12.4 329.7 0.0 0.0 47.6 0.0 5017.7 15.3 8.9 0.0 219.7 35.0 0.9 4.8 0.0 0.0 49.7 35.1 134.2 6.8 0.0 0.0 5.3 30.3 0.0 4.9 0.3 0.0 37.7 8.8 0.0 3728.4 0.1 2.1 17.8 2261.3 1.0 0.0 700.9 670.1 1.1 0.0 22.4 59.8 0.0 13.0 93.4 67.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.9 181.9 63.9 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 279.6 0.0 0.1 0.1 123.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 12.4 0.0 3713.4 0.0 2.4 0.0 2.8 0.0 1.4 0.3 1.2 5.7 0.6 0.0 0.0 0.1 3.2 3.7 0.0 0.0 0.0 0.0 0.0 15.6 8.5 56.2 0.0 0.0 0.0 8.0 10.7 0.0 15.2 0.0 78.9 6.0 0.3 0.0 0.0 2.9 0.0 10.8 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 10918.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 12.3 0.0 0.4 325.4 0.0 4.8 0.2 IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 18 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.7;U-698: 1.8" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" 8.6 5.3 0.1 196.9 0.1 35.6 72.8 0.0 1.9 18.6 0.2 260.2 354.8 3.3 0.0 15.7 5.2 12.6 1.4 0.1 0.1 2.3 6.1 28.5 46.8 1.3 0.0 8.2 3.1 0.4 0.0 0.7 0.5 4.3 182.6 0.0 120.1 0.5 0.0 0.0 171.1 12.0 0.3 100.2 305.5 1.0 0.2 14.6 2.9 0.0 414.0 61.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.2 276.3 0.6 2.5 0.2 180.8 0.3 0.3 0.0 0.1 0.1 99.0 0.2 29.1 0.1 0.1 0.0 1.9 0.1 0.1 1.3 0.0 0.5 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ2 ENSG00000211904 "Immunoglobulin heavy joining 2" 14 105865199-105865250 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "cervix: 48.7;intestine: 127.5;lymphoid tissue: 174.5" "Cell type enriched" "Detected in single" 6 "Plasma cells: 3.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "medulla oblongata: 3.8" "Group enriched" "Detected in some" 18 "MAIT T-cell: 49.0;naive B-cell: 12.6" "Group enriched" "Detected in many" 45 "B-cells: 12.6;T-cells: 49.0" "Group enriched" "Detected in some" 25 "Daudi: 3.8;K-562: 1.1" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (1.27e-2)" "prognostic favorable (1.05e-4)" "unprognostic (7.40e-2)" "unprognostic (6.38e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.33e-6)" "unprognostic (4.31e-2)" "unprognostic (1.68e-1)" "unprognostic (5.48e-2)" "unprognostic (4.60e-1)" 2.0 0.0 0.2 0.0 0.5 13.3 20.5 0.2 2.0 48.7 0.1 87.2 0.0 5.4 17.9 18.0 2.1 0.8 0.1 0.2 0.4 1.2 12.0 0.0 7.6 3.8 0.8 7.7 18.9 0.6 0.0 0.0 0.5 15.0 127.5 0.0 0.0 7.1 0.0 0.0 0.0 5.8 0.6 18.8 18.2 0.1 0.5 19.6 5.1 0.0 174.5 6.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 49.0 1.3 0.4 1.6 0.4 12.6 0.0 0.2 0.2 0.0 0.6 0.0 0.0 17.1 0.2 0.5 0.2 2.0 0.2 0.4 3.8 0.8 0.5 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHJ4 ENSG00000240041 "Immunoglobulin heavy joining 4" 14 105864215-105864260 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 416.7;lymphoid tissue: 1568.0;urinary bladder: 551.2" "Cell type enriched" "Detected in single" 148 "Plasma cells: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 187 "memory B-cell: 6029.7;naive B-cell: 2618.0" "Lineage enriched" "Detected in all" 261 "B-cells: 6029.7" "Cell line enriched" "Detected in some" 87 "U-698: 3990.3" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 7.2 0.0 2.9 0.0 240.0 0.9 10.8 0.0 3.6 377.5 0.0 0.0 0.0 200.2 7.4 4.1 12.3 0.9 2.5 0.0 39.1 0.0 0.0 8.9 30.7 0.0 0.0 13.6 0.0 2.5 22.3 7.0 416.7 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.0 45.4 7.3 3.7 3.1 32.3 3.9 0.0 1568.0 551.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 14.0 17.5 0.0 0.0 0.0 0.0 6.8 3.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 45.8 0.0 0.0 6.2 0.0 3990.3 0.0 12.2 0.0 13.9 3.6 5.4 5.0 1.3 3.0 6029.7 13.2 4.0 23.1 2618.0 1.5 6.0 20.1 3.3 6.0 0.0 6.6 1048.2 7.2 2.9 0.9 10.8 0.9 2.5 8.9 30.7 22.3 2.0 3.1 1.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.5;breast: 73.2;intestine: 72.3;prostate: 32.7" "Cell type enriched" "Detected in single" 397 "Plasma cells: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 263 "memory B-cell: 1081.0" "Lineage enriched" "Detected in many" 263 "B-cells: 1081.0" "Group enriched" "Detected in some" 11 "HL-60: 10.5;REH: 14.0;RH-30: 18.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" 33.5 0.0 0.7 0.0 3.7 0.0 73.2 0.7 2.0 0.0 2.0 72.3 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.9 4.2 4.5 29.4 17.1 0.0 3.1 1.0 0.0 4.7 0.0 0.0 0.0 1.9 32.7 0.2 0.2 0.0 0.0 0.0 7.9 0.0 0.0 1.6 0.0 0.0 0.4 1.3 0.0 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.6 2.1 1.2 0.7 1081.0 0.4 0.6 4.1 0.0 2.6 0.9 2.3 0.7 0.6 0.0 1.1 316.0 0.7 3.7 0.7 2.0 0.9 4.2 3.1 1.0 1.9 1.6 1.3 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 56 "Plasma cells: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cell line enhanced" "Detected in some" "U-266/84: 1.3;U-937: 1.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.9 142.4 0.0 2.6 38.6 1.0 0.0 0.0 2.1 0.5 0.9 0.3 0.0 3.0 2.4 47.0 0.4 0.4 0.1 0.0 0.0 3.7 0.0 0.0 0.3 3.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 151.4 0.3 0.0 0.7 0.0 10.7 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.2 0.0 3.5 3.5 0.8 0.3 0.0 0.2 316.2 0.5 0.6 0.5 112.7 0.6 0.3 14.8 0.2 1.0 0.0 0.1 89.2 0.0 0.0 0.1 0.9 0.3 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 76.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 231.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HL-60: 1.8;JURKAT: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 3100000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" 6.8 1.4 0.1 33.7 0.0 0.0 8.5 0.0 0.3 56.3 0.1 30.5 0.0 5.7 0.0 46.2 6.5 4.6 1.8 0.0 0.1 7.0 6.4 17.7 0.0 1.2 0.1 19.6 1.4 0.1 0.4 0.3 0.0 3.1 14.0 0.0 76.3 0.0 0.1 0.8 24.0 2.1 0.0 186.8 37.0 14.2 0.0 0.4 14.5 0.0 18.4 63.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.8 0.1 0.0 0.0 2.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 3.6 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 19.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 231.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 5.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.9;lymphoid tissue: 30.3;stomach 1: 17.5" "Cell type enriched" "Detected in single" 20 "Plasma cells: 2.0" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.3" "Immunoglobulin genes" NA NA 380000000 "Cluster 32: T-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" 0.2 0.1 0.0 3.7 0.0 1.8 18.9 0.0 0.0 0.3 0.0 4.5 1.1 0.5 0.0 6.4 0.2 0.6 0.1 0.0 0.0 0.2 0.2 3.5 7.6 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 6.1 0.0 11.5 0.0 0.0 0.1 2.3 0.7 0.0 6.9 17.5 0.1 0.0 2.9 0.3 0.0 30.3 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 1.1 0.6 0.3 0.0 1.1 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "urinary bladder: 204.7" "Group enriched" "Detected in some" 17 "B-cells: 2.4;Plasma cells: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.7" "Lineage enriched" "Detected in single" 58 "B-cells: 12.7" "Cell line enhanced" "Detected in single" "MOLT-4: 1.5" "Immunoglobulin genes" NA NA 120000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (9.63e-3)" "unprognostic (6.78e-2)" "unprognostic (5.64e-2)" "unprognostic (4.04e-2)" "prognostic favorable (7.25e-4)" "unprognostic (4.56e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-1)" "unprognostic (1.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "unprognostic (6.79e-2)" "unprognostic (1.36e-1)" 8.1 3.4 0.0 13.8 0.0 5.9 3.8 0.0 0.0 0.8 0.0 19.5 15.7 0.4 0.0 8.3 1.1 4.7 1.0 0.0 0.0 1.5 1.4 5.4 41.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 27.8 0.0 23.5 1.9 0.0 0.2 9.8 0.1 0.0 26.2 13.1 0.5 0.0 10.3 1.1 0.0 51.1 204.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 85 "Plasma cells: 231.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0;MOLT-4: 6.2;SCLC-21H: 1.1;U-698: 1.9" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" 7.7 1.4 0.0 0.0 0.1 0.1 6.5 0.0 0.0 21.4 0.1 56.9 0.0 6.9 0.0 7.0 5.7 77.4 0.7 0.0 0.1 7.0 4.8 18.0 0.0 2.5 0.0 2.0 0.8 1.8 0.5 0.0 3.0 4.6 139.1 0.0 55.9 13.0 0.1 0.5 31.7 6.8 0.0 170.2 31.0 0.1 0.0 0.0 25.2 0.0 0.0 162.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 1.3 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV1OR15-9 "IGHV1/OR15-9, IGHV1OR159, VSIG7" ENSG00000188403 "Immunoglobulin heavy variable 1/OR15-9 (non-functional)" 15 19964666-19965101 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "breast: 4.1;intestine: 8.6;lymphoid tissue: 8.6;stomach 1: 8.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 14: B-cells - Humoral immune response" "prognostic favorable (1.79e-4)" "unprognostic (8.93e-2)" "unprognostic (2.97e-3)" "unprognostic (9.34e-2)" "prognostic favorable (6.84e-4)" "unprognostic (1.64e-1)" "unprognostic (1.57e-1)" "unprognostic (3.79e-1)" "unprognostic (1.07e-4)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (2.66e-1)" "unprognostic (2.11e-1)" 0.0 0.0 0.0 8.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 8.6 3.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 8.3 0.0 0.0 1.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 14.1;lymphoid tissue: 12.8;salivary gland: 7.6;stomach 1: 16.7;urinary bladder: 20.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Cell line enriched" "Detected in single" 6 "MOLT-4: 1.3" "Immunoglobulin genes" NA NA 19000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" 0.1 0.1 0.0 12.8 0.0 3.3 1.1 0.0 0.0 2.8 0.0 10.3 14.1 0.4 0.0 0.5 1.1 1.1 0.5 0.0 0.0 0.1 0.7 2.4 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 11.1 0.0 7.6 0.5 0.0 0.2 6.0 0.6 0.0 5.3 16.7 0.0 0.0 0.0 0.0 0.0 2.2 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-38 ENSG00000211958 "Immunoglobulin heavy variable 3-38 (non-functional)" A0A0C4DH36 14 106410493-106411021 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.9;lymphoid tissue: 10.4;stomach 1: 5.9;urinary bladder: 7.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.4;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 34 "B-cells: 3.4" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.03e-5)" "unprognostic (5.11e-2)" "unprognostic (3.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.31e-3)" "unprognostic (8.40e-2)" "unprognostic (3.54e-2)" "unprognostic (2.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.75e-8)" "unprognostic (6.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.99e-1)" "unprognostic (2.52e-1)" 0.3 0.1 0.0 5.9 0.0 1.6 3.3 0.0 0.0 1.4 0.0 7.7 9.9 0.1 0.0 0.9 0.1 0.9 0.2 0.0 0.0 0.1 0.4 1.8 2.2 0.0 0.0 0.6 0.4 0.0 0.0 0.2 0.0 0.2 7.0 0.0 4.1 0.0 0.0 0.2 5.8 0.0 0.0 4.4 5.9 0.7 0.0 0.0 0.0 0.0 10.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790691-106791233 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.7;lymphoid tissue: 121.6;urinary bladder: 101.3" "Cell type enriched" "Detected in some" 271 "Plasma cells: 3507.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "memory B-cell: 52.4" "Lineage enriched" "Detected in many" 50 "B-cells: 52.4" "Cell line enhanced" "Detected in some" "NB-4: 1.3;RH-30: 1.3;RPMI-8226: 1.2;TIME: 2.2;U-698: 5.8" "Immunoglobulin genes" NA NA 9600000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" 4.8 2.6 0.1 18.4 0.1 15.5 7.0 0.0 0.6 5.2 0.1 75.7 28.4 3.0 2.9 17.4 3.4 0.3 0.3 0.0 0.0 1.9 5.3 8.6 2.7 0.5 0.0 2.3 3.4 0.1 0.2 0.1 0.1 1.9 47.6 0.0 46.6 0.9 0.1 0.3 58.2 5.4 0.1 121.6 29.4 0.0 0.0 2.6 2.2 0.5 12.1 101.3 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.3 0.2 0.0 0.0 0.1 1.3 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.1 0.0 0.3 0.0 5.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 52.4 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.1 0.0 0.6 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.1 7.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3507.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Cholangiocytes: 1.5;Erythroid cells: 5.3;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cell line enhanced" "Detected in some" "Daudi: 1.4;HEL: 1.1;HL-60: 1.1;K-562: 1.7" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" 4.4 13.3 0.0 9.4 0.0 15.8 10.5 0.0 0.5 4.7 0.3 76.9 141.8 5.1 0.0 4.0 3.9 19.1 10.4 0.0 0.0 3.0 9.8 12.3 0.0 0.1 0.0 1.5 5.9 0.0 0.5 0.1 0.2 4.3 58.0 0.0 30.6 3.9 0.4 0.2 23.6 0.4 0.1 83.0 47.5 0.4 0.0 0.0 4.1 0.0 0.2 81.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 69.9 0.1 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.9;lymphoid tissue: 327.0;salivary gland: 102.6" "Cell type enriched" "Detected in some" 454 "Plasma cells: 19404.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 861 "Daudi: 2948.0" "Immunoglobulin genes" NA NA 27000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.47e-4)" "unprognostic (9.70e-2)" "prognostic favorable (8.33e-4)" "unprognostic (6.96e-3)" "unprognostic (1.42e-1)" "prognostic favorable (7.79e-4)" "unprognostic (1.06e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-1)" "unprognostic (3.07e-2)" "unprognostic (2.42e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (4.70e-6)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" 11.3 1.2 0.1 0.0 0.2 0.0 12.6 0.0 1.5 9.3 0.0 103.9 0.0 2.1 1.9 87.3 2.6 1.3 0.7 0.0 0.3 4.7 6.6 22.2 0.0 0.6 0.0 2.5 1.9 0.6 0.8 0.1 0.2 6.5 0.0 0.0 102.6 0.0 0.5 3.2 74.1 0.0 0.3 327.0 27.5 0.2 0.1 0.0 7.7 0.0 0.0 46.4 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 2948.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.1 1.1 0.2 0.0 0.0 0.1 1.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.7 0.3 0.4 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.5 0.0 0.3 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 42.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 1.4 27.5 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 19404.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 2.3 0.0 0.1 0.3 IGHV3OR15-7 IGHV3/OR15-7 ENSG00000259490 "Immunoglobulin heavy variable 3/OR15-7 (pseudogene)" 15 19987656-19988117 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 2.0;stomach 1: 1.8" "Cell type enriched" "Detected in single" 104 "Plasma cells: 10.4" "Cancer enhanced" "Detected in many" "lung cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.08e-2)" "unprognostic (8.21e-2)" "unprognostic (1.08e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.43e-5)" "unprognostic (4.56e-1)" "unprognostic (3.12e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-4)" "unprognostic (7.46e-2)" "unprognostic (1.35e-1)" "unprognostic (3.50e-1)" "unprognostic (1.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-10 IGHV3/OR16-10 ENSG00000233732 "Immunoglobulin heavy variable 3/OR16-10 (non-functional)" 16 32995048-32995505 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 4.8;intestine: 6.3;lymphoid tissue: 8.3;salivary gland: 7.0;stomach 1: 5.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.1" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.40e-3)" "unprognostic (4.22e-2)" "unprognostic (3.45e-2)" "unprognostic (3.41e-4)" "unprognostic (2.20e-1)" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" 0.0 0.2 0.0 1.0 0.0 1.1 0.7 0.2 0.3 0.0 0.0 4.1 6.2 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.3 0.0 7.0 0.0 0.0 0.0 2.1 1.1 0.1 1.4 5.6 3.5 0.1 0.9 0.2 0.0 8.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.4 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-12 IGHV3/OR16-12 ENSG00000270467 "Immunoglobulin heavy variable 3/OR16-12 (non-functional)" 16 33802764-33803217 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 13.7;lymphoid tissue: 20.3;stomach 1: 9.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "memory B-cell: 4.5" "Lineage enriched" "Detected in single" 46 "B-cells: 4.5" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (2.04e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-3)" "unprognostic (1.07e-1)" "unprognostic (7.10e-2)" "unprognostic (5.02e-1)" "unprognostic (1.29e-1)" 0.0 0.0 0.0 7.7 0.0 1.0 3.3 0.0 0.0 1.2 0.0 8.3 13.7 0.0 0.0 1.1 0.1 1.6 0.0 0.0 0.0 0.1 0.3 1.3 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 4.1 0.0 2.5 0.0 0.0 0.0 3.6 0.0 0.0 2.1 9.8 0.2 0.0 1.0 0.0 0.0 20.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-13 IGHV3/OR16-13 ENSG00000271178 "Immunoglobulin heavy variable 3/OR16-13 (non-functional)" 16 33827214-33827661 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "stomach cancer: 4.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 28 "memory B-cell: 18.1" "Lineage enriched" "Detected in single" 181 "B-cells: 18.1" "Cell line enriched" "Detected in some" 818 "Daudi: 1604.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.59e-4)" "unprognostic (4.14e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.23e-5)" "unprognostic (1.34e-1)" "unprognostic (2.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (3.26e-5)" "unprognostic (6.83e-2)" "unprognostic (1.71e-1)" "unprognostic (3.09e-1)" "unprognostic (3.04e-1)" 0.2 0.0 0.1 5.3 0.0 0.6 0.4 0.0 0.1 1.3 0.0 6.7 6.0 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.9 0.0 7.0 0.0 0.0 0.0 4.0 0.1 0.0 32.2 4.2 0.0 0.0 1.0 0.3 0.0 10.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1604.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-8 IGHV3/OR16-8 ENSG00000271130 "Immunoglobulin heavy variable 3/OR16-8 (non-functional)" 16 33009175-33009620 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 32.0;lymphoid tissue: 49.4;stomach 1: 32.9;urinary bladder: 40.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "memory B-cell: 7.3" "Lineage enriched" "Detected in single" 74 "B-cells: 7.3" "Not detected" "Not detected" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (2.58e-4)" "unprognostic (3.25e-2)" "unprognostic (9.53e-3)" "unprognostic (1.56e-1)" "unprognostic (2.43e-4)" "unprognostic (1.31e-1)" "unprognostic (4.47e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (2.60e-7)" "unprognostic (2.24e-2)" "unprognostic (4.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.16e-2)" 2.3 0.8 0.0 13.8 0.0 5.9 4.5 0.0 0.0 2.7 0.0 30.1 32.0 0.2 0.0 1.9 0.7 5.3 0.0 0.0 0.0 0.1 0.9 3.2 3.6 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 14.8 0.0 10.0 0.0 0.0 0.0 9.0 1.8 0.0 5.8 32.9 0.1 0.0 3.0 0.7 0.0 49.4 40.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3OR16-9 IGHV3/OR16-9 ENSG00000270472 "Immunoglobulin heavy variable 3/OR16-9 (non-functional)" 16 32066065-32066358 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 73.2;lymphoid tissue: 88.5;stomach 1: 79.0;urinary bladder: 54.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 136 "memory B-cell: 20.0;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 200 "B-cells: 20.0" "Not detected" "Not detected" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.32e-3)" "unprognostic (8.31e-2)" "unprognostic (2.49e-3)" "prognostic favorable (1.29e-4)" "unprognostic (2.29e-1)" "unprognostic (5.22e-2)" "unprognostic (1.91e-1)" "unprognostic (1.31e-1)" "unprognostic (1.01e-5)" "unprognostic (1.57e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "unprognostic (1.55e-1)" 11.1 9.8 0.1 32.9 0.0 13.7 17.1 0.3 0.6 8.3 0.0 73.2 45.8 0.9 0.0 26.5 1.5 8.3 2.9 0.0 0.1 0.8 3.7 9.1 13.0 0.6 0.0 6.2 1.3 0.1 0.0 0.0 0.4 1.1 37.7 0.0 49.3 0.0 0.0 0.0 38.6 0.3 0.4 27.0 79.0 0.3 0.1 8.6 0.1 0.0 88.5 54.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.3 0.6 0.0 0.1 0.6 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 12 "B-cells: 72318.1;Plasma cells: 96515.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Group enriched" "Detected in many" 6 "Daudi: 9909.1;U-266/70: 10337.6;U-266/84: 3927.9;U-698: 12154.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" 1025.4 2379.8 13.1 20500.0 13.3 6315.2 11287.7 11.3 33.6 3649.2 26.7 35196.7 24515.5 877.3 474.1 5708.4 1137.6 5995.3 810.4 11.4 16.7 1176.6 1580.5 5824.2 21356.1 25.1 18.2 2214.9 462.9 72.6 101.8 22.2 15.3 843.6 30618.3 4.0 19606.1 2123.2 32.9 250.8 17061.1 1259.7 43.5 26904.1 22740.5 1083.9 13.4 8576.0 2151.1 8.1 63075.6 24817.5 705.0 20.2 17.1 0.0 0.0 0.0 0.0 0.0 103.7 0.0 0.0 0.1 0.0 0.0 0.0 9909.1 15.3 0.0 1.0 22.2 0.0 0.0 0.0 510.2 0.0 30.9 0.0 0.0 0.0 67.8 29.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.8 0.4 0.0 0.0 18.3 83.2 28.8 0.0 0.0 16.7 56.4 1509.5 0.6 0.0 79.6 146.1 19.6 1.5 6.0 0.5 0.5 17.2 66.7 0.0 56.9 24.3 44.0 10337.6 3927.9 12154.4 0.0 28.9 0.0 47.5 55.6 31.6 24.6 11.2 21.7 39143.0 28.3 18.3 46.6 35081.5 15.2 16.8 65.2 24.1 29.1 1735.4 23.7 8567.0 13.1 13.3 11.3 33.6 11.4 16.7 25.1 18.2 15.3 43.5 13.4 20.2 58.6 336.5 1863.8 0.0 72318.1 0.0 189.2 0.0 2.2 0.0 8.8 7.0 5.7 163.0 88.5 0.0 0.0 48.0 452.1 39.8 3.9 0.0 2.8 0.7 0.3 72.8 77.8 1658.9 0.0 0.2 37.3 186.5 64.7 0.4 849.0 15.5 340.2 334.8 8.9 0.0 0.0 35.1 0.0 496.3 0.0 11.0 0.0 64.4 0.0 0.0 26.4 0.0 59.8 0.0 0.0 0.0 25.9 0.4 96515.7 193.2 0.3 45.2 12.4 0.0 0.0 3.7 38.4 0.3 0.2 5.9 0.0 49.4 6505.3 0.1 50.2 1.9 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2670.6;lymphoid tissue: 2226.1;salivary gland: 1187.7;stomach 1: 1719.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22200.6;naive B-cell: 20663.6" "Lineage enriched" "Detected in all" 52 "B-cells: 22200.6" "Group enriched" "Detected in many" 7 "HDLM-2: 213.9;RPMI-8226: 179.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" 67.9 154.0 0.6 1862.6 0.9 296.5 312.9 0.1 4.0 158.7 0.7 1762.7 2670.6 37.5 0.0 308.3 14.3 114.1 19.6 0.6 0.6 27.0 61.7 236.7 693.3 4.3 1.4 71.6 72.5 1.9 0.0 1.1 1.2 46.0 1364.3 0.0 1187.7 20.2 2.9 5.2 1974.3 28.2 1.5 1097.1 1719.7 44.8 0.9 73.5 5.1 0.0 2226.1 494.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 3.5 0.0 0.0 0.0 213.9 0.0 9.7 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 8.0 3.6 0.0 0.0 7.4 2.5 179.1 0.0 0.0 3.2 17.5 4.8 0.0 0.0 0.0 0.0 29.6 10.7 0.0 3.4 3.7 7.6 5.3 0.0 29.0 0.0 1.8 0.0 19.7 33.6 12.8 10.3 7.7 12.8 22200.6 15.0 8.1 23.3 20663.6 9.5 9.6 42.6 10.8 18.6 430.3 17.4 2451.2 0.6 0.9 0.1 4.0 0.6 0.6 4.3 1.4 1.2 1.5 0.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 1010.8;lymphoid tissue: 997.2;stomach 1: 710.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 12 "spinal cord: 18.3" "Group enriched" "Detected in all" 26 "memory B-cell: 8663.4;naive B-cell: 7153.9" "Lineage enriched" "Detected in all" 28 "B-cells: 8663.4" "Group enriched" "Detected in some" 6 "HDLM-2: 105.2;RPMI-8226: 89.2;U-698: 41.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 15.1 19.6 0.8 886.7 0.7 115.0 111.2 0.3 1.3 19.2 0.5 587.3 1010.8 7.6 0.0 68.8 7.9 44.8 9.3 0.9 0.6 14.3 41.1 101.9 490.2 1.2 0.5 31.1 0.0 0.0 0.0 1.9 1.5 18.2 546.6 0.6 362.3 12.6 8.7 2.5 726.3 19.9 18.3 548.6 710.1 9.7 0.9 53.9 5.1 3.9 997.2 236.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 105.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 89.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 0.0 0.0 41.2 0.0 0.0 0.0 17.0 8.6 57.9 1.9 1.1 9.2 8663.4 3.0 3.3 5.9 7153.9 5.7 5.1 61.8 7.1 15.2 309.9 7.8 660.0 0.8 0.7 0.3 1.3 0.9 0.6 1.2 0.5 1.5 18.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3282.9;lymphoid tissue: 2905.5;stomach 1: 2295.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36413.7;naive B-cell: 27723.7" "Lineage enriched" "Detected in all" 48 "B-cells: 36413.7" "Cell line enhanced" "Detected in some" "BEWO: 16.9;Daudi: 23.5;HDLM-2: 58.4;RPMI-8226: 43.3;SH-SY5Y: 27.6;U-698: 25.7" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 80.0 268.7 0.6 2905.5 0.7 407.6 414.6 0.3 4.1 110.0 0.5 1844.1 3282.9 29.5 62.5 433.0 33.3 138.1 34.8 0.6 1.1 48.2 104.6 481.3 932.6 2.9 0.7 117.5 29.3 1.7 0.0 1.3 1.3 56.4 1849.6 0.3 1142.3 54.8 3.9 17.3 2184.0 78.1 2.6 1246.0 2295.9 39.7 1.8 113.5 11.4 0.0 2661.5 645.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.0 9.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 2.0 10.4 0.0 0.0 0.0 0.0 9.1 43.3 0.0 0.0 6.7 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.3 8.5 3.3 0.0 25.7 0.0 0.0 0.0 114.4 64.9 20.3 24.9 9.5 16.8 36413.7 15.8 15.2 32.5 27723.7 22.7 16.1 60.0 21.5 25.4 759.9 22.8 3519.3 0.6 0.7 0.3 4.1 0.6 1.1 2.9 0.7 1.3 2.6 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Cell type enriched" "Detected in single" 13 "B-cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Cell line enriched" "Detected in some" 24 "U-698: 3392.4" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" 25.2 42.2 0.5 1365.8 0.7 164.5 236.5 0.6 4.5 73.7 0.3 1194.4 1221.3 13.4 5.8 130.7 8.8 78.5 26.1 0.9 0.7 18.0 30.8 157.6 529.7 1.6 0.6 63.3 29.2 6.6 0.0 4.1 1.2 22.8 1171.9 0.0 643.7 17.1 0.0 5.8 1078.7 40.6 4.9 672.7 1066.6 12.4 0.7 61.5 4.3 0.0 1213.5 436.6 0.0 0.9 17.7 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 142.3 0.0 0.0 0.0 0.0 0.0 7.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 58.5 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.3 3.5 11.4 3.2 1.9 3392.4 0.0 8.1 0.0 3.3 10.1 10.2 3.8 1.3 2.2 9254.1 18.4 3.5 7.4 8737.5 9.5 3.4 9.4 7.6 3.4 373.6 8.8 1167.3 0.5 0.7 0.6 4.5 0.9 0.7 1.6 0.6 1.2 4.9 0.7 0.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.2;lymphoid tissue: 17.2;urinary bladder: 5.6" "Cell type enriched" "Detected in some" 24 "Plasma cells: 73.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 247 "memory B-cell: 21.2;naive B-cell: 28.2" "Lineage enriched" "Detected in single" 283 "B-cells: 28.2" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" 0.1 0.2 0.0 2.9 0.0 0.8 2.4 0.0 0.0 0.5 0.0 4.5 3.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.4 1.2 2.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 2.6 0.6 0.0 0.0 2.0 0.2 0.0 3.7 1.5 0.0 0.0 0.9 0.1 0.0 17.2 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 410 "Plasma cells: 5131.4" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" 2.8 0.5 0.0 3.8 0.1 2.3 8.3 0.0 0.1 3.6 0.1 32.7 1.3 1.4 0.0 4.6 2.7 2.6 0.2 0.2 0.2 4.0 2.2 17.9 6.8 0.0 0.2 0.4 0.5 0.0 0.1 0.0 0.0 1.6 2.0 0.0 73.3 8.6 0.0 0.5 19.1 0.0 0.5 63.0 21.2 0.1 0.0 4.7 3.3 0.2 9.1 16.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5131.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 IGKV1D-37 "IGKV1D37, O4" ENSG00000250036 "Immunoglobulin kappa variable 1D-37 (non-functional)" P0DSN7 2 89884740-89885216 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;stomach 1: 15.0;urinary bladder: 20.1" "Cell type enriched" "Detected in single" 11 "Plasma cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 209 "memory B-cell: 13.6;naive B-cell: 29.1" "Lineage enriched" "Detected in single" 284 "B-cells: 29.1" "Cell line enriched" "Detected in single" 5 "HDLM-2: 2.5" HPA048721 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (2.68e-1)" 0.1 0.0 0.0 4.2 0.0 3.3 2.4 0.0 0.0 0.8 0.0 8.6 12.7 0.1 0.4 2.1 0.2 0.5 0.2 0.4 0.0 0.1 0.4 0.8 4.1 0.0 0.1 0.4 1.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 7.1 0.0 0.2 0.0 6.0 0.2 0.0 6.5 15.0 0.2 0.0 1.1 0.1 0.0 2.5 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.2;lymphoid tissue: 14.2;salivary gland: 5.6" "Cell type enriched" "Detected in some" 29 "Plasma cells: 338.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 323 "memory B-cell: 32.7;naive B-cell: 31.8" "Lineage enriched" "Detected in single" 328 "B-cells: 32.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 38.3" HPA048721 Approved "Immunoglobulin genes" NA NA 1900000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" 0.5 0.0 0.0 5.3 0.0 0.7 1.2 0.0 0.0 0.6 0.0 4.2 1.6 0.1 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.3 0.3 1.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 2.6 0.0 5.6 0.0 0.0 0.0 2.8 0.0 0.0 8.3 1.9 0.0 0.0 1.2 0.6 0.0 14.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 338.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1OR2-108 "IGKV1/OR2-108, IGKV1OR2108, IGO1" ENSG00000231292 "Immunoglobulin kappa variable 1/OR2-108 (non-functional)" 2 113406396-113406872 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.2;lymphoid tissue: 56.7" "Cell type enriched" "Detected in single" 652 "Plasma cells: 65.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "memory B-cell: 13.5;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 58 "B-cells: 13.5" "Cell line enhanced" "Detected in some" "Daudi: 6.6;HBEC3-KT: 7.2;hTEC/SVTERT24-B: 4.1;REH: 4.1" "Not detected" "Not detected" HPA048721 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.53e-6)" "unprognostic (2.73e-2)" "unprognostic (1.55e-2)" "unprognostic (3.37e-1)" "unprognostic (3.64e-3)" "unprognostic (3.57e-2)" "unprognostic (3.20e-1)" "unprognostic (5.21e-2)" "unprognostic (1.17e-1)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (9.96e-6)" "unprognostic (6.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" 0.5 1.4 0.1 23.3 0.4 11.2 16.7 0.0 0.3 4.8 5.6 38.2 21.8 0.3 0.0 6.8 0.4 5.5 0.2 0.8 0.0 0.1 1.4 6.9 14.0 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.9 22.1 0.1 15.2 0.5 0.1 4.8 13.9 0.8 0.0 12.7 16.9 0.0 0.1 3.8 1.3 0.0 56.7 21.7 0.1 0.0 2.1 0.7 0.3 0.0 0.0 0.0 0.4 0.0 2.2 0.3 1.5 3.0 1.2 6.6 0.0 0.9 1.1 0.3 0.0 7.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 4.1 2.4 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.6 0.4 0.0 1.6 4.1 0.6 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.6 0.0 1.3 0.2 0.2 0.1 1.2 0.1 0.4 0.4 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 13.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.1 0.4 0.0 0.3 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 272.7;lymphoid tissue: 474.9;urinary bladder: 935.2" "Cell type enriched" "Detected in some" 252 "Plasma cells: 5620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.1" "Lineage enriched" "Detected in single" 482 "B-cells: 48.1" "Cell line enhanced" "Detected in single" "NB-4: 1.3" "Immunoglobulin genes" NA NA 840000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" 13.7 14.6 0.1 65.8 0.1 27.4 91.8 0.0 0.6 11.5 0.4 272.7 250.8 3.2 1.1 82.0 6.6 24.1 14.7 0.2 1.0 7.8 8.6 30.0 131.7 0.6 0.1 6.3 5.6 0.2 0.9 0.2 0.9 5.4 180.6 0.0 219.3 3.3 0.3 3.3 98.5 7.9 1.1 474.9 106.8 1.2 0.2 23.7 11.1 0.0 235.6 935.2 14.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.6 0.2 1.0 0.6 0.1 0.9 1.1 0.2 0.3 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5620.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.7;lymphoid tissue: 25.5;urinary bladder: 15.3" "Cell type enriched" "Detected in single" 207 "Plasma cells: 165.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Cell line enriched" "Detected in single" 8 "U-937: 1.0" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.21e-4)" "unprognostic (1.78e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.09e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (4.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.74e-5)" "unprognostic (7.60e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (3.47e-1)" 0.6 0.8 0.0 4.3 0.0 2.7 6.1 0.0 0.7 0.5 0.0 16.8 19.7 0.1 0.0 1.5 0.4 3.5 0.1 1.8 0.0 0.6 0.5 1.8 6.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 7.2 0.0 9.6 0.5 0.0 0.3 7.0 0.1 0.1 25.0 5.2 0.1 0.1 1.7 0.4 0.0 25.5 15.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 222 "Plasma cells: 1314.8" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cell line enriched" "Detected in some" 6 "U-698: 51.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" 0.4 0.4 0.0 6.4 0.0 4.3 5.9 0.0 0.1 0.8 0.0 15.3 11.8 0.4 0.0 1.0 0.4 0.8 0.8 0.1 0.1 1.4 0.7 2.8 6.7 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.5 11.2 0.0 13.0 4.6 0.0 1.2 8.5 2.0 0.0 29.3 22.2 0.1 0.0 1.6 0.8 0.0 33.5 5.6 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 51.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 124.9 0.0 0.1 0.1 164.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 19.3 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1314.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 34 "Plasma cells: 196.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cell line enhanced" "Detected in single" "U-266/70: 2.1" HPA047702 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" 1.3 0.7 0.3 35.9 0.2 8.9 6.4 0.0 0.1 1.7 0.0 38.6 32.2 0.8 0.0 2.4 2.1 2.7 0.5 0.0 0.1 2.1 1.3 12.4 13.0 0.1 0.3 1.5 0.5 0.0 0.1 0.0 0.1 0.7 26.6 0.0 18.8 0.3 0.0 0.1 23.6 0.7 0.2 29.9 27.7 0.2 0.0 4.2 2.3 0.0 58.5 17.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 152.5 0.0 0.0 0.1 146.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 30.2 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 196.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 415 "Plasma cells: 207.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 48.7" HPA047702 Approved "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" 0.1 0.0 0.0 5.5 0.2 1.3 0.1 0.0 0.1 0.2 0.0 4.0 4.6 0.0 0.0 1.9 0.1 1.5 0.0 0.1 0.1 0.0 0.2 0.5 1.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 2.1 0.1 0.0 0.0 4.4 0.0 0.0 3.8 4.4 0.0 0.1 0.2 0.6 0.0 4.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3OR2-268 "IGKV268, IGKV3/OR2-268, IGKV3/OR2-268A, IGKV3OR2-268A" ENSG00000233999 "Immunoglobulin kappa variable 3/OR2-268 (non-functional)" 2 87338511-87339035 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 100.4;lymphoid tissue: 85.7" "Cell type enriched" "Detected in some" 302 "Plasma cells: 2604.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 220.0;naive B-cell: 78.9" "Lineage enriched" "Detected in many" 7 "B-cells: 220.0" "Group enriched" "Detected in some" 71 "U-266/70: 183.9;U-266/84: 593.2" HPA047702 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (8.06e-4)" "unprognostic (1.69e-3)" "unprognostic (1.19e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.26e-1)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (8.68e-2)" "unprognostic (2.61e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.12e-6)" "unprognostic (2.80e-2)" "unprognostic (3.83e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-1)" 0.4 1.3 0.3 45.8 0.4 11.8 28.5 0.1 0.6 3.4 0.2 100.4 33.9 0.9 0.0 1.3 0.7 24.7 1.3 0.3 0.4 0.6 2.6 7.5 23.8 0.3 0.2 3.3 1.2 0.0 0.0 0.1 0.2 1.6 59.5 0.0 29.4 1.6 0.0 0.6 27.7 4.1 0.1 19.3 34.0 0.4 0.2 10.3 1.2 0.0 85.7 24.4 0.8 0.5 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.5 0.2 183.9 593.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 220.0 2.8 0.1 0.1 78.9 0.0 0.1 0.1 0.1 0.0 0.2 30.0 32.7 0.3 0.4 0.1 0.6 0.3 0.4 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2604.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.3;lymphoid tissue: 141.0" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1715.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 28.8;naive B-cell: 9.8" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cell line enriched" "Detected in some" 6 "U-266/70: 10.5" "Immunoglobulin genes" NA NA 250000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" 2.2 0.4 0.0 41.6 0.0 12.0 37.4 0.0 0.1 3.3 0.0 97.3 38.8 1.8 0.6 8.4 1.9 5.9 0.5 0.0 0.0 2.7 2.6 11.9 64.4 0.2 0.0 2.1 0.8 0.0 0.1 0.0 0.0 1.5 79.3 0.0 43.5 9.0 0.0 0.5 38.5 5.0 0.1 63.8 36.3 0.9 0.0 10.2 3.5 0.0 141.0 37.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1715.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 37.3;granulocytes: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cell line enriched" "Detected in many" 5 "U-266/70: 600.3" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" 132.3 163.1 2.2 1208.8 1.9 641.9 903.4 1.7 7.0 190.8 4.4 3038.0 3264.2 63.1 2.1 535.0 113.2 640.0 104.5 1.7 2.2 148.2 114.7 470.6 2372.4 3.9 1.7 135.6 69.8 8.0 13.2 1.9 2.2 71.5 2133.6 0.7 2047.0 124.0 4.9 28.8 1389.9 78.0 2.6 3332.0 2335.3 23.7 2.3 873.2 224.5 0.0 5586.9 1948.8 79.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 1.0 0.0 1.9 0.2 0.0 0.0 6.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 9.1 0.0 0.0 1.1 10.2 2.0 0.0 0.0 2.3 8.9 33.4 0.0 0.0 6.3 11.1 1.4 0.0 0.0 0.0 0.0 0.3 2.5 0.0 1.3 4.3 2.6 600.3 119.9 36.5 0.0 3.5 0.0 4.2 7.7 2.0 3.7 1.7 2.9 5729.2 3.8 2.5 6.0 5821.4 0.9 2.2 7.6 2.8 4.8 5.2 3.4 897.2 2.2 1.9 1.7 7.0 1.7 2.2 3.9 1.7 2.2 2.6 2.3 3.4 0.0 6.4 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Group enriched" "Detected in many" 40 "B-cells: 24632.2;Plasma cells: 18795.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Group enriched" "Detected in many" 190 "RPMI-8226: 62032.1;U-266/70: 102644.1;U-266/84: 83511.6" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" 386.6 782.7 7.7 3871.2 6.2 2741.4 2183.6 4.6 14.9 815.5 11.4 8217.0 9734.6 194.3 207.0 1690.0 231.5 2091.8 318.3 4.6 5.7 301.6 382.3 1442.8 5543.4 11.1 5.0 540.2 112.7 16.8 31.0 7.5 6.6 264.0 5055.4 0.7 5934.2 384.9 8.6 74.2 5290.6 306.2 6.6 7090.0 10849.9 256.0 5.4 2071.4 491.7 0.6 19988.7 6482.1 176.7 10.7 120.6 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 221.4 12.0 0.0 0.0 61.9 0.0 0.0 0.0 30.5 0.0 7.7 0.0 0.0 0.0 19.2 343.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 64.7 0.0 0.0 70.1 27.7 52.3 0.0 0.0 45.3 436.2 62032.1 0.0 0.0 46.7 45.7 5.6 43.0 17.3 0.0 17.7 57.2 11.7 0.0 38.9 23.4 78.2 102644.1 83511.6 298.8 0.7 21.9 0.7 9.9 18.6 5.6 5.8 3.0 5.7 11361.1 5.8 4.5 10.9 10650.3 3.5 4.7 118.0 5.8 8.7 303.3 6.5 2385.6 7.7 6.2 4.6 14.9 4.6 5.7 11.1 5.0 6.6 6.6 5.4 10.7 4.1 32.1 121.0 0.0 24632.2 0.0 0.3 0.0 1.2 0.0 16.1 3.0 3.9 44.3 8.1 0.0 0.0 0.3 8.0 28.0 0.0 0.0 0.0 0.0 0.1 86.3 62.5 222.4 0.0 0.0 0.3 42.5 14.8 0.0 65.6 0.0 222.8 539.9 2.1 0.0 0.0 21.5 0.0 134.5 0.0 0.0 0.0 8.5 0.0 0.0 11.4 0.0 15.5 0.0 0.0 0.0 20.6 0.0 18795.5 0.0 0.0 1.4 1.5 0.0 0.0 0.2 10.2 0.0 0.0 2.8 0.0 0.1 538.6 0.0 23.7 0.0 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV1-50 ENSG00000211645 "Immunoglobulin lambda variable 1-50 (non-functional)" A0A075B6I6 22 22327300-22327814 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.4;lymphoid tissue: 14.7;stomach 1: 20.4" "Cell type enriched" "Detected in single" 2575 "Plasma cells: 1545.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 21 "memory B-cell: 11.0;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 33 "B-cells: 11.0" "Cell line enhanced" "Detected in single" "HEK 293: 1.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-4)" "unprognostic (8.01e-2)" "unprognostic (1.28e-3)" "unprognostic (6.91e-2)" "unprognostic (2.10e-1)" "prognostic favorable (7.08e-4)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (7.38e-2)" "unprognostic (1.58e-4)" "unprognostic (4.89e-3)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" 0.5 0.5 0.1 6.1 0.1 3.3 6.7 1.7 1.9 0.5 0.0 5.4 16.4 0.6 1.2 2.4 0.5 0.8 0.0 0.6 0.0 0.2 0.2 4.4 1.9 0.6 0.0 0.9 0.1 0.1 0.1 0.0 0.6 0.3 4.5 0.7 4.6 0.3 0.4 0.0 9.4 0.2 0.0 3.9 20.4 0.4 0.0 0.6 0.2 0.0 14.7 9.3 0.1 1.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.3 0.5 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.1 0.0 0.3 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 1.7 1.9 0.6 0.0 0.6 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1545.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 210 "Plasma cells: 2488.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Group enriched" "Detected in some" 7 "RPMI-8226: 13.4;U-266/70: 22.3;U-266/84: 7.2" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" 3.4 0.3 0.0 73.0 0.0 23.7 67.1 0.0 0.3 6.7 0.1 271.5 262.0 4.2 0.0 39.6 10.8 36.3 12.5 0.0 0.0 2.0 2.8 12.6 37.6 0.1 0.0 4.1 1.1 2.1 0.2 0.1 0.4 1.7 138.6 0.0 64.3 4.9 0.1 0.3 150.2 6.5 0.0 95.8 72.5 0.5 0.0 22.1 2.8 0.0 224.4 18.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 13.4 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.3 7.2 0.1 0.1 0.1 0.0 0.2 1.8 0.0 1.6 0.0 0.8 321.2 0.3 1.3 0.1 126.9 0.7 0.6 0.5 5.0 0.1 0.2 0.1 69.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2488.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.2;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.7;NK-cell: 5.6" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.6;T-cells: 4.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" 0.8 1.2 0.0 3.9 0.0 2.7 1.9 0.0 0.3 0.3 0.1 7.3 5.5 0.5 0.0 1.0 0.6 3.3 0.0 0.0 0.0 0.1 0.5 2.7 15.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 5.1 1.7 0.0 0.2 2.7 0.1 0.0 4.6 8.2 0.9 0.0 3.9 0.2 0.0 30.1 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 1.1 9.2 1.0 4.0 0.0 6.7 0.0 0.2 0.0 5.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 80.3;urinary bladder: 42.9" "Group enriched" "Detected in some" 49 "B-cells: 6.2;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 393 "memory B-cell: 107.2;naive B-cell: 121.2" "Lineage enriched" "Detected in single" 417 "B-cells: 121.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 350000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" 1.5 0.0 0.0 6.9 0.0 6.3 4.9 0.0 0.0 0.7 0.0 10.7 9.9 0.2 0.0 2.5 1.9 1.2 0.6 0.0 0.0 0.7 1.3 4.7 13.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.6 10.8 0.0 10.8 0.0 0.0 0.1 5.2 0.6 0.0 12.8 13.0 0.3 0.0 3.5 0.2 0.0 80.3 42.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 107.2 0.0 0.1 0.1 121.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 40.5;intestine: 43.5;lymphoid tissue: 97.5;salivary gland: 49.0" "Cell type enriched" "Detected in some" 116 "Plasma cells: 6697.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 160000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" 2.2 0.3 0.0 0.0 0.0 0.4 5.5 0.0 0.4 3.3 0.0 43.5 0.0 0.7 0.0 40.5 2.0 0.0 0.2 0.0 0.0 2.5 3.1 9.6 0.0 0.1 0.0 0.6 0.6 0.0 0.2 0.0 0.1 1.1 0.2 0.0 49.0 0.0 0.1 0.7 42.1 0.0 0.0 97.5 14.1 0.4 0.0 0.0 4.0 0.0 1.4 14.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 57.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6697.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 57 "Plasma cells: 1304.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Cell line enhanced" "Detected in some" "Daudi: 1.9;RPMI-8226: 1.4;U-698: 1.5" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" 8.0 0.8 0.0 31.2 0.1 15.8 45.7 0.0 0.5 4.9 0.0 161.9 132.8 3.6 0.5 7.9 3.3 22.1 3.5 0.0 0.1 3.1 4.2 13.0 59.0 0.0 0.0 4.1 2.2 0.0 1.0 0.2 0.1 2.3 129.3 0.0 72.5 4.7 0.1 0.5 57.1 17.7 0.0 168.6 115.9 0.5 0.0 31.3 6.4 0.7 238.7 31.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 132.0 0.0 0.0 0.0 54.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.2 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1304.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.2 0.0 IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 180 "Plasma cells: 6758.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cell line enhanced" "Detected in some" "Daudi: 8.0;RPMI-8226: 2.8;U-698: 6.6" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" 15.1 3.8 0.0 59.8 0.3 44.2 171.7 0.1 0.9 4.1 0.1 400.6 162.4 4.4 0.0 43.7 3.0 56.0 5.2 0.0 1.6 5.7 7.7 44.9 82.2 0.4 0.0 9.0 6.2 0.1 0.8 0.1 0.2 2.5 298.6 0.0 107.2 5.2 0.5 0.8 133.1 12.1 0.1 248.1 250.7 0.7 0.2 57.3 8.7 0.0 459.1 444.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.3 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 183.6 0.1 0.0 0.1 82.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 15.2 0.0 0.3 0.1 0.9 0.0 1.6 0.4 0.0 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6758.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 INPP5K SKIP ENSG00000132376 "Inositol polyphosphate-5-phosphatase K" Q9BT40 17 1494577-1516742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Congenital muscular dystrophy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 96.1;Late spermatids: 345.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (7.47e-2)" "prognostic favorable (3.91e-4)" "unprognostic (8.91e-2)" "prognostic favorable (2.33e-5)" "unprognostic (3.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.50e-1)" "unprognostic (7.50e-2)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.47e-6)" "unprognostic (4.71e-2)" "unprognostic (9.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.20e-2)" "unprognostic (4.28e-3)" "unprognostic (1.04e-1)" 34.7 15.2 25.8 12.9 26.0 34.5 29.2 25.3 30.2 19.5 61.5 19.6 10.2 17.0 13.1 17.9 15.3 10.7 28.9 29.8 25.7 16.7 15.0 27.3 18.6 26.9 26.9 17.8 21.9 13.7 14.8 18.6 26.9 19.6 12.7 15.9 18.1 12.9 40.5 30.1 19.4 12.0 25.4 22.8 19.1 20.4 26.9 25.8 30.4 25.2 19.7 18.2 17.9 27.0 14.9 24.0 9.2 18.4 22.5 13.2 12.1 12.0 23.6 15.8 19.6 15.7 9.1 14.6 23.2 22.2 12.5 19.4 22.1 9.6 14.3 35.3 33.0 8.6 18.1 5.9 31.3 7.9 17.0 16.2 24.0 15.8 16.1 10.0 25.3 25.3 9.4 25.9 10.6 12.5 24.5 7.1 3.9 23.9 14.6 19.0 6.7 14.6 12.8 10.3 7.1 18.0 10.2 21.6 24.3 13.0 17.9 7.3 16.2 13.6 13.3 19.8 16.8 12.9 23.4 7.4 14.7 9.1 17.3 104.3 42.2 74.3 48.7 41.9 39.7 27.5 44.5 50.2 36.2 24.4 37.5 41.1 74.7 42.3 66.6 27.0 75.1 62.5 25.8 26.0 25.3 30.2 29.8 25.7 26.9 26.9 26.9 25.4 26.9 27.0 26.1 32.1 14.1 8.5 20.6 30.0 15.7 10.8 18.8 7.8 15.6 12.2 35.8 8.6 11.0 23.9 2.1 13.9 27.5 26.0 13.7 19.4 96.1 10.3 6.9 27.0 17.4 25.2 5.4 24.3 16.4 15.5 13.3 17.4 19.7 7.7 28.5 10.2 11.9 20.2 5.9 17.3 14.2 18.4 19.0 345.7 11.5 13.8 32.0 2.8 37.1 23.1 27.8 2.5 7.0 27.1 23.4 7.5 18.0 13.3 33.2 11.2 6.4 7.9 19.7 12.6 15.3 35.5 20.4 18.1 30.3 31.1 27.2 5.8 13.5 17.4 IRAG2 "JAW1, LRMP" ENSG00000118308 "Inositol 1,4,5-triphosphate receptor associated 2" Q12912 12 25004342-25108334 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fertilization, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 60.3;lymphoid tissue: 202.8" "Cell type enhanced" "Detected in some" "Adipocytes: 13.1;B-cells: 6.2;dendritic cells: 42.9;Hofbauer cells: 14.1;Plasma cells: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 210.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Daudi: 634.3;REH: 221.9;U-698: 722.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA002967, HPA007356, HPA018505" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" NA NA 6700 "Cluster 45: Eosinophils - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum, Plasma membrane" "HPA002967: AB_1079161, HPA007356: , HPA018505: AB_1851988" "unprognostic (3.78e-2)" "unprognostic (2.59e-3)" "unprognostic (7.54e-2)" "unprognostic (7.08e-3)" "unprognostic (2.36e-1)" "unprognostic (1.48e-3)" "unprognostic (7.98e-2)" "unprognostic (4.08e-2)" "unprognostic (7.32e-2)" "unprognostic (1.15e-1)" "unprognostic (3.59e-2)" "unprognostic (7.97e-2)" "unprognostic (7.25e-3)" "unprognostic (7.72e-2)" "unprognostic (9.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.59e-2)" 9.6 1.9 8.5 47.2 5.4 60.3 6.5 2.3 5.6 2.4 3.2 10.1 8.7 2.5 2.8 5.2 5.1 7.8 2.4 6.6 2.6 9.4 6.2 7.7 171.7 6.0 4.4 5.7 30.7 1.5 2.4 4.4 6.1 3.4 9.2 1.1 3.6 4.4 1.1 5.8 19.1 4.5 3.6 37.5 10.1 1.0 2.8 95.1 4.9 1.6 202.8 14.5 8.3 4.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 634.3 0.3 0.0 0.0 0.2 0.0 2.4 0.0 22.1 0.0 37.8 0.0 0.1 0.0 49.7 54.2 0.0 0.0 0.7 0.0 0.1 0.0 31.5 7.8 40.6 0.0 0.0 54.5 91.2 0.1 0.0 0.0 221.9 0.3 63.8 0.7 29.7 0.2 0.1 0.2 0.3 0.2 0.1 0.0 36.7 0.5 0.0 1.5 0.0 0.1 40.4 7.8 722.4 0.2 21.8 0.0 80.2 21.0 210.1 23.6 40.8 20.2 66.1 14.9 24.2 22.4 51.0 25.5 25.4 151.3 49.0 51.5 20.8 2.7 20.2 8.5 5.4 2.3 5.6 6.6 2.6 6.0 4.4 6.1 3.6 2.8 4.6 13.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 ITGAL "CD11A, LFA-1" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 118.6;monocytes: 36.8;NK-cells: 152.4;Plasma cells: 46.6;T-cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 121.7" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "HMC-1: 608.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" 4.2 1.4 0.3 36.7 0.5 36.8 2.3 0.3 1.0 2.4 0.5 5.5 6.0 2.3 1.0 2.5 3.0 7.0 1.4 0.3 0.4 2.6 10.6 22.0 62.4 1.6 1.1 1.3 1.0 0.5 1.2 3.0 1.4 2.4 8.6 0.0 5.3 1.4 0.9 1.4 19.7 3.6 0.7 64.9 8.6 1.0 1.6 55.2 3.5 0.9 46.4 6.9 2.3 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.1 0.0 1.1 608.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 134.3 0.0 0.0 43.3 3.5 0.0 0.0 0.0 0.1 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.4 26.0 0.0 0.0 0.0 0.0 0.0 36.6 12.5 0.0 0.1 3.8 0.0 5.3 24.4 17.0 56.6 48.0 27.7 4.8 21.4 42.7 22.3 1.7 9.4 29.7 14.3 24.2 121.7 6.0 15.6 43.6 0.3 0.5 0.3 1.0 0.3 0.4 1.6 1.1 1.4 0.7 1.6 2.1 1.2 6.4 10.5 0.7 19.1 0.8 0.3 0.0 0.0 0.4 1.2 1.0 1.9 0.0 1.9 1.8 0.0 0.2 118.6 0.3 0.0 0.1 0.5 4.1 0.6 2.3 0.0 4.8 3.6 0.0 0.6 1.4 1.1 0.9 5.1 0.1 5.3 4.9 19.3 0.0 2.8 0.2 0.0 30.0 3.4 0.7 0.0 31.5 1.8 15.9 36.8 0.1 152.4 0.5 1.6 0.0 0.0 0.0 46.6 0.1 0.9 0.3 6.7 0.9 0.0 1.2 0.7 0.2 0.2 0.1 0.3 0.7 84.9 0.1 0.0 0.2 ITGAM "CD11B, CR3A, MAC-1" ENSG00000169896 "Integrin subunit alpha M" P11215 16 31259967-31332892 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Innate immunity" "Integrin, Receptor" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 182.8" "Group enriched" "Detected in many" 4 "dendritic cells: 45.4;granulocytes: 35.5;Hofbauer cells: 47.2;Kupffer cells: 117.7;Langerhans cells: 45.5;Macrophages: 83.2;Microglial cells: 41.2;monocytes: 87.4;NK-cells: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HMC-1: 50.0;NB-4: 19.9;U-937: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002274, CAB025091, CAB072870" Enhanced NA NA 1000000 "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB025091: , CAB072870: AB_2665722, HPA002274: AB_1078435" "unprognostic (1.82e-2)" "unprognostic (1.70e-2)" "unprognostic (8.78e-2)" "unprognostic (2.54e-2)" "unprognostic (2.40e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (3.29e-3)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.93e-5)" "unprognostic (9.89e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (3.99e-2)" "unprognostic (5.03e-2)" 13.4 4.7 3.4 24.7 3.5 182.8 3.0 4.5 4.2 3.3 4.8 3.0 2.2 2.0 0.7 2.6 2.3 5.9 2.9 3.6 5.1 1.0 3.5 16.4 7.4 6.7 5.7 1.6 2.3 1.3 0.1 7.7 7.3 1.5 3.4 0.3 2.4 2.2 1.4 1.7 3.5 11.2 6.5 13.1 3.1 1.4 8.6 5.2 1.0 3.1 10.4 8.0 0.2 10.8 0.8 1.8 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.5 0.8 1.3 0.9 0.0 0.4 0.1 0.0 0.4 0.0 7.6 0.0 1.0 0.0 0.0 0.0 1.8 50.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.3 0.1 1.0 0.0 2.2 0.0 0.0 0.0 0.5 0.4 0.0 0.2 4.3 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 22.6 0.1 93.3 55.7 70.2 31.1 20.9 1.9 4.8 3.3 9.5 9.5 1.0 0.9 7.7 58.4 54.4 3.2 0.6 1.2 27.0 3.4 3.5 4.5 4.2 3.6 5.1 6.7 5.7 7.3 6.5 8.6 10.8 1.4 3.2 9.8 0.7 9.3 1.1 0.3 1.5 0.0 0.0 1.8 3.8 2.3 4.3 1.8 0.0 0.0 0.3 45.4 0.0 0.0 1.2 0.5 0.3 0.4 1.6 3.6 9.4 1.0 0.0 0.7 1.1 1.1 0.5 35.5 0.5 2.2 1.2 47.2 0.0 1.0 0.1 0.0 117.7 45.5 1.8 0.3 83.2 0.0 41.2 87.4 0.0 75.2 3.0 0.3 0.9 0.0 0.0 4.5 0.5 0.0 0.2 0.9 0.0 13.1 1.2 0.5 0.7 0.9 0.5 1.0 0.8 14.9 0.0 0.3 0.2 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 106.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.9" "Group enriched" "Detected in all" 5 "granulocytes: 42.9;monocytes: 25.9" "Cell line enhanced" "Detected in all" "WM-115: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA055230: AB_2682748" "unprognostic (1.93e-3)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "prognostic favorable (8.56e-4)" "unprognostic (4.27e-1)" "unprognostic (2.04e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.24e-2)" "unprognostic (2.86e-2)" "unprognostic (8.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-3)" "unprognostic (2.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.20e-1)" "unprognostic (7.25e-3)" 60.0 27.2 88.3 15.5 105.9 17.3 45.3 84.7 92.7 57.0 57.2 60.1 44.4 66.8 11.6 24.8 30.3 19.4 59.2 92.5 80.7 35.6 48.3 31.6 9.0 90.2 95.8 27.1 30.7 14.8 20.6 6.8 83.0 38.8 16.4 9.3 21.0 21.7 40.9 22.2 58.5 23.4 83.2 38.1 34.2 29.5 100.4 6.9 25.4 16.1 6.6 62.5 35.0 100.7 28.1 56.6 10.3 26.3 22.5 12.6 27.8 11.8 17.5 22.9 13.8 32.8 48.9 17.7 57.4 18.6 8.7 32.5 29.6 50.3 7.2 65.9 13.1 39.2 14.6 28.5 16.8 17.9 41.5 8.2 29.5 11.6 26.3 9.9 22.8 18.0 21.9 19.8 11.3 74.6 15.5 25.5 22.0 36.4 25.5 29.1 15.1 26.3 15.5 46.3 28.0 35.5 29.6 59.0 49.5 7.8 79.5 21.7 18.0 15.9 17.3 27.0 18.9 19.3 19.1 11.4 14.6 13.8 110.8 5.3 9.8 18.2 3.2 15.4 1.9 3.3 2.0 2.1 7.0 1.0 1.2 2.2 42.9 2.4 25.9 3.5 3.0 5.1 88.3 105.9 84.7 92.7 92.5 80.7 90.2 95.8 83.0 83.2 100.4 100.7 11.8 12.8 11.1 32.0 10.8 7.4 7.5 8.3 2.8 10.2 11.8 7.6 24.3 17.2 5.1 29.5 18.8 9.7 12.9 73.5 13.7 19.2 12.7 18.1 12.5 12.4 28.8 5.9 45.1 27.3 10.0 8.9 13.3 21.2 16.5 9.2 13.9 31.3 19.4 6.7 21.6 24.8 4.1 44.7 11.8 30.3 14.9 30.5 26.6 16.9 23.2 17.2 18.6 31.7 46.5 44.6 38.7 48.2 13.2 15.2 106.6 23.0 3.3 13.7 19.7 7.4 17.8 4.3 14.3 7.0 4.4 6.8 12.7 10.3 34.5 11.0 ITSN1 "ITSN, MGC134948, MGC134949, SH3D1A, SH3P17" ENSG00000205726 "Intersectin 1" Q15811 21 33642400-33899861 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 217.4;Inhibitory neurons: 151.9;Rod photoreceptor cells: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 5.5;non-classical monocyte: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 115.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018007 Approved Supported "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA018007: AB_1851836" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (3.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (3.94e-2)" "unprognostic (7.33e-3)" "unprognostic (1.31e-2)" "unprognostic (3.23e-1)" "unprognostic (3.25e-2)" "unprognostic (1.16e-2)" "unprognostic (6.78e-3)" "unprognostic (2.37e-1)" "unprognostic (6.02e-2)" "unprognostic (5.64e-2)" 55.5 15.5 18.0 9.9 18.4 6.8 27.9 16.4 26.2 19.8 22.8 14.7 8.9 20.3 12.0 11.4 16.7 19.8 20.9 18.3 14.0 10.9 26.4 11.5 6.8 14.5 13.6 19.6 5.0 7.0 6.7 24.4 14.9 14.5 11.0 28.5 7.9 22.3 22.0 11.9 9.7 18.4 8.8 15.4 11.1 12.3 17.0 5.0 10.3 22.0 3.9 15.4 13.4 14.1 36.3 14.9 70.4 23.4 32.3 30.8 115.3 35.8 34.4 20.6 19.8 56.7 27.0 8.5 28.3 43.1 42.7 13.7 42.2 24.9 22.0 3.5 18.6 10.3 30.9 26.7 24.4 7.4 9.9 30.5 22.0 38.6 21.2 23.5 55.3 9.8 13.7 5.8 33.4 8.2 10.3 9.8 104.5 12.6 11.3 13.2 33.7 17.6 30.9 14.7 13.2 14.4 51.4 10.6 12.6 44.6 13.0 7.2 50.2 22.9 30.9 18.1 12.5 7.0 20.8 7.9 20.8 22.9 26.0 0.0 4.2 5.5 0.3 3.2 0.3 0.0 0.5 0.1 1.3 0.0 0.2 0.1 0.2 0.1 5.1 0.3 0.0 0.8 18.0 18.4 16.4 26.2 18.3 14.0 14.5 13.6 14.9 8.8 17.0 14.1 19.8 25.6 18.6 217.4 1.8 18.1 22.6 10.8 36.5 73.1 12.2 8.1 81.8 18.6 14.5 11.0 91.8 20.8 1.1 22.4 0.0 19.9 10.2 13.3 67.7 21.3 9.1 47.4 110.9 12.5 28.0 31.9 19.4 21.0 2.5 30.7 28.2 54.2 55.6 65.6 151.9 7.2 20.3 30.0 10.9 8.6 24.8 27.3 10.6 74.0 10.8 46.9 0.0 80.4 46.4 37.1 10.3 71.5 3.1 18.3 16.8 16.6 18.8 146.2 13.1 20.1 39.7 32.4 47.7 8.9 11.8 15.6 2.7 21.4 10.5 27.2 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1434.2;Inhibitory neurons: 480.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "CACO-2: 57.4;HEL: 35.3;OE19: 20.1;SH-SY5Y: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 83000 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 9.4 6.3 15.0 2.2 23.4 0.3 6.7 0.0 31.3 9.1 4.9 2.0 2.5 7.7 1.9 9.5 4.6 2.9 12.8 21.3 3.4 3.8 5.8 4.4 0.9 0.0 6.6 3.1 8.8 3.5 4.1 4.2 0.0 2.8 1.8 4.5 2.8 4.9 27.2 2.0 2.0 6.2 0.0 8.5 12.1 2.6 10.7 0.5 5.1 19.3 1.6 2.6 6.0 20.9 0.7 1.1 6.2 1.3 0.9 0.2 8.1 2.5 1.5 2.4 1.1 57.4 4.5 0.2 0.8 6.4 3.9 0.4 1.4 0.0 2.0 0.0 0.7 35.3 0.4 8.9 0.1 0.0 0.0 0.4 0.0 0.5 0.1 2.6 2.9 0.1 8.3 0.2 0.7 4.2 0.0 0.0 3.5 20.1 5.4 1.8 2.8 0.0 0.2 0.5 2.1 15.9 0.7 0.5 0.5 6.0 1.2 0.1 14.4 7.0 2.8 1.0 1.1 0.0 0.6 0.0 0.8 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.7 0.2 0.2 0.0 0.0 0.0 1.6 0.4 15.0 23.4 0.0 31.3 21.3 3.4 0.0 6.6 0.0 0.0 10.7 20.9 56.2 3.2 3.9 191.3 0.6 1.7 1.5 0.3 0.6 61.2 6.1 7.1 32.1 18.6 0.5 16.5 6.2 8.0 2.5 40.5 1.9 5.0 57.0 15.0 18.8 23.2 9.6 5.3 1434.2 8.4 1.7 5.9 29.0 7.4 3.8 4.4 45.3 21.7 1.0 0.0 480.8 16.4 0.0 1.6 1.1 64.0 3.7 5.3 3.6 48.7 0.0 4.7 8.2 162.3 63.1 4.4 21.0 33.1 0.3 2.6 34.8 3.6 8.4 2.7 19.7 8.8 21.8 5.2 2.6 4.9 1.1 14.2 1.0 17.5 12.3 1.6 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "retina: 113.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 115.6;Cone photoreceptor cells: 212.7;Excitatory neurons: 150.6;Inhibitory neurons: 89.9;Rod photoreceptor cells: 386.9" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Region enhanced" "Detected in many" "cerebral cortex: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.4;CACO-2: 2.2;HL-60: 1.1;hTCEpi: 1.2;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001979, HPA042434" Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB001979: , HPA042434: AB_2677996" "unprognostic (4.51e-1)" "unprognostic (1.72e-1)" "unprognostic (6.54e-3)" "unprognostic (4.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (8.09e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-1)" "unprognostic (8.32e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-4)" 10.7 1.5 4.3 0.3 6.6 0.0 2.8 0.0 17.8 1.2 0.0 6.2 0.2 7.3 0.8 1.7 6.0 0.6 1.2 6.6 0.0 0.3 2.4 0.3 0.0 0.0 0.0 0.4 0.3 0.2 2.7 0.1 0.0 2.2 0.6 113.3 1.6 3.1 7.3 0.5 2.0 5.0 0.0 0.3 3.4 0.4 0.0 0.1 0.1 4.4 0.0 3.8 0.9 7.9 0.0 0.0 0.3 0.0 1.4 0.1 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.2 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.9 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.9 0.7 0.6 0.9 0.0 0.0 0.7 0.0 0.0 0.9 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 6.6 0.0 17.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 7.9 20.2 0.0 2.2 7.8 0.5 0.8 0.2 0.0 0.0 115.6 0.9 0.5 3.4 1.5 0.7 0.0 212.7 0.0 0.4 0.0 0.0 0.0 0.7 19.8 2.9 8.0 0.0 0.0 150.6 0.0 0.0 1.4 0.0 4.2 3.8 1.5 0.0 5.7 0.1 18.5 89.9 0.0 0.0 0.0 0.3 0.8 4.4 0.4 0.0 12.2 0.0 38.2 0.0 43.2 3.3 0.1 0.0 34.6 0.1 0.1 0.0 0.2 4.0 386.9 0.0 0.9 7.0 0.2 0.5 0.2 0.3 0.1 0.4 0.2 0.0 0.1 KCNE5 KCNE1L ENSG00000176076 "Potassium voltage-gated channel subfamily E regulatory subunit 5" Q9UJ90 X 109623700-109625172 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Alport syndrome, Deafness, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.8;skeletal muscle: 4.0;tongue: 4.9" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Erythroid cells: 3.8;monocytes: 9.4;Muller glia cells: 5.3;Peritubular cells: 3.8" "Group enriched" "Detected in some" 8 "glioma: 7.9;testis cancer: 2.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;hTEC/SVTERT24-B: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042316 Uncertain Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA042316: AB_10795397" "unprognostic (5.33e-2)" "unprognostic (2.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-3)" "unprognostic (3.27e-2)" "unprognostic (9.46e-2)" "unprognostic (1.05e-1)" "unprognostic (4.62e-3)" "unprognostic (7.83e-2)" "unprognostic (5.64e-6)" "unprognostic (5.10e-2)" "unprognostic (9.06e-2)" "unprognostic (1.36e-1)" "unprognostic (5.37e-3)" 1.1 0.8 3.2 0.1 5.4 1.6 0.5 9.4 2.7 0.2 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.7 2.7 6.6 0.7 0.2 0.4 0.0 6.3 9.8 0.5 0.1 0.0 0.3 0.2 6.9 0.3 0.0 0.2 0.2 0.3 4.0 0.1 0.1 0.1 4.0 0.9 0.1 0.3 7.8 2.3 0.1 4.9 0.0 0.3 0.2 4.6 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.3 0.3 0.0 0.8 0.3 0.0 0.1 1.0 1.1 0.7 0.0 0.0 1.5 0.2 0.5 2.0 0.5 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.4 0.5 0.0 0.9 0.4 0.7 0.3 0.3 0.9 0.2 0.2 0.1 0.4 0.4 0.1 0.0 0.3 0.0 0.3 0.8 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 3.2 5.4 9.4 2.7 2.7 6.6 6.3 9.8 6.9 4.0 7.8 4.6 0.1 0.0 1.1 4.6 0.1 0.0 0.0 0.0 1.2 0.0 0.3 1.1 0.6 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.3 0.0 0.5 0.1 0.2 0.0 3.8 0.1 0.4 1.2 1.4 0.0 0.5 1.3 0.7 1.1 0.0 0.6 0.0 0.1 0.0 0.0 2.0 0.0 0.0 1.2 2.1 0.0 1.0 9.4 5.3 0.0 0.0 0.0 0.3 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.1 0.0 0.8 0.2 0.1 0.0 0.1 KCNIP2 KCHIP2 ENSG00000120049 "Potassium voltage-gated channel interacting protein 2" Q9NS61 10 101825974-101843920 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4;brain: 139.6;heart muscle: 307.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.3;Cardiomyocytes: 135.7;Cone photoreceptor cells: 25.0;Excitatory neurons: 23.3;Horizontal cells: 48.8;Inhibitory neurons: 41.9" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 12.7" "Group enriched" "Detected in all" 4 "amygdala: 96.8;basal ganglia: 234.9;cerebral cortex: 106.9;hippocampal formation: 142.6;olfactory bulb: 144.0" "Low region specificity" "Detected in all" HPA066717 Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA066717: " "unprognostic (5.92e-2)" "unprognostic (2.16e-1)" "unprognostic (3.48e-3)" "unprognostic (5.77e-4)" "unprognostic (1.34e-1)" "unprognostic (1.31e-3)" "unprognostic (8.80e-2)" "unprognostic (9.11e-3)" "unprognostic (1.14e-1)" "unprognostic (5.34e-2)" "unprognostic (3.18e-2)" "unprognostic (7.20e-2)" "unprognostic (1.49e-9)" "unprognostic (9.85e-2)" "unprognostic (1.81e-1)" "unprognostic (3.27e-1)" "unprognostic (8.37e-4)" 227.4 6.8 74.5 3.5 139.6 0.9 67.1 48.8 84.5 7.4 40.5 5.0 1.8 4.1 4.1 2.5 4.9 3.1 307.5 98.8 50.6 2.8 2.3 2.5 8.1 47.5 51.6 11.5 2.4 1.7 19.7 2.9 48.1 5.2 4.7 52.6 9.9 3.5 8.0 5.9 5.3 2.6 50.3 5.7 2.7 8.5 57.1 2.3 3.5 5.4 8.3 4.8 4.4 60.8 1.7 2.6 2.5 3.2 1.0 1.1 0.6 1.2 1.0 0.6 0.9 3.6 3.4 1.6 0.9 0.8 0.7 1.7 0.9 0.4 0.6 2.4 2.0 21.3 3.0 1.9 0.9 1.4 12.7 2.6 1.7 1.0 1.4 3.7 1.0 4.7 6.3 1.8 1.0 1.2 0.8 4.0 0.8 0.7 0.6 1.0 0.2 1.4 1.0 1.1 7.4 1.2 0.8 0.6 2.4 1.5 2.2 0.9 2.3 1.3 2.0 0.6 1.2 1.7 1.9 1.7 1.4 5.3 0.2 0.0 0.0 0.7 0.0 0.5 0.1 0.9 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 74.5 139.6 48.8 84.5 98.8 50.6 47.5 51.6 48.1 50.3 57.1 60.8 0.4 0.0 0.0 8.5 2.3 0.4 0.1 0.3 0.0 54.3 0.3 0.5 135.7 0.0 0.1 1.8 25.0 0.2 0.0 0.8 0.0 0.2 6.6 0.0 0.2 1.6 0.0 0.0 23.3 0.0 0.2 5.8 0.0 0.0 0.0 0.8 0.4 0.1 2.2 48.8 41.9 0.4 0.0 0.6 0.8 5.2 1.8 0.3 0.0 1.0 0.5 8.3 0.0 5.5 3.7 0.3 0.2 0.7 0.3 0.1 0.5 0.1 0.2 4.7 0.0 0.1 1.3 2.5 5.5 0.5 0.0 0.3 0.1 0.5 0.3 0.1 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KIF17 "KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3" ENSG00000117245 "Kinesin family member 17" Q9P2E2 1 20664014-20718017 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 23.2" "Cell type enhanced" "Detected in many" "Adipocytes: 18.9;Early spermatids: 44.0;Hepatic stellate cells: 15.4;Late spermatids: 88.7;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;hTERT-HME1: 3.7;U-2 OS: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032085 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA032085: AB_10669917" "unprognostic (4.15e-3)" "unprognostic (8.60e-3)" "unprognostic (6.43e-2)" "unprognostic (1.12e-2)" "unprognostic (7.68e-2)" "unprognostic (3.70e-1)" "unprognostic (1.07e-2)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (7.34e-3)" "unprognostic (8.73e-2)" "unprognostic (3.63e-3)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-2)" 0.0 0.2 2.3 0.0 2.2 0.0 0.0 0.0 3.3 0.3 1.8 0.2 0.1 0.4 0.0 0.0 1.8 0.0 0.0 2.3 4.9 0.4 0.1 0.2 0.0 0.6 1.4 0.2 0.0 0.0 0.6 0.0 0.4 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.5 0.3 0.0 0.0 23.2 3.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.8 0.7 0.4 0.0 0.0 0.0 0.1 1.2 1.6 0.6 0.4 0.2 0.4 0.0 0.5 0.9 0.3 0.0 0.6 0.4 0.4 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.1 0.3 0.5 3.7 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.3 0.6 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.2 2.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.2 0.0 3.3 2.3 4.9 0.6 1.4 0.4 0.3 3.1 0.0 18.9 0.0 0.0 0.7 0.2 1.7 0.0 0.1 0.6 0.0 0.2 0.3 2.8 0.0 0.2 1.8 4.2 0.1 2.8 0.1 0.0 0.0 44.0 2.8 0.3 15.2 0.0 0.0 11.0 0.0 0.1 0.9 0.0 0.2 0.0 0.0 15.4 0.5 5.1 0.0 2.8 0.0 0.0 1.6 9.8 88.7 1.2 3.2 1.8 1.9 0.2 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.1 0.1 0.1 0.3 3.5 0.3 19.7 0.5 2.7 3.2 4.3 0.1 1.3 1.6 0.2 5.2 0.1 0.2 KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 244.8;choroid plexus: 142.7;heart muscle: 185.0;skeletal muscle: 561.0;tongue: 389.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 315.4;Distal enterocytes: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024602: AB_1852480, HPA045020: AB_2679187" "unprognostic (3.89e-2)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (8.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (6.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.45e-1)" "unprognostic (4.90e-3)" "prognostic favorable (2.26e-9)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (7.10e-3)" 54.6 18.6 200.1 25.1 230.9 6.3 36.3 184.0 210.0 33.9 142.7 63.3 53.3 44.4 7.9 75.7 31.5 28.0 185.0 164.4 175.0 37.9 46.4 49.6 10.0 219.0 216.9 24.1 51.6 55.1 10.5 18.6 197.0 36.4 33.2 4.3 38.3 36.7 561.0 53.4 51.4 36.3 200.7 26.5 51.2 17.7 200.8 11.3 38.7 389.2 16.7 51.4 37.3 244.8 104.1 97.6 32.2 69.4 74.5 44.5 51.0 80.8 64.3 63.2 38.3 70.7 24.5 16.6 46.7 127.2 41.2 105.3 58.4 107.2 44.6 40.2 68.7 12.0 124.1 57.4 50.7 4.9 34.6 46.0 109.9 85.2 58.0 59.6 87.2 14.5 45.9 28.4 62.6 61.5 14.7 8.0 25.1 68.1 63.4 15.1 54.1 17.2 55.7 71.9 7.8 15.3 114.2 63.0 34.9 30.6 62.0 14.9 185.5 84.8 63.7 62.2 99.3 10.8 9.9 8.9 62.6 20.9 43.0 0.5 0.4 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.4 0.2 0.2 1.2 0.3 0.2 0.2 0.3 0.1 200.1 230.9 184.0 210.0 164.4 175.0 219.0 216.9 197.0 200.7 200.8 244.8 24.8 54.5 50.6 6.5 6.8 16.8 19.0 25.6 12.5 12.5 24.8 14.2 315.4 48.6 28.1 25.8 0.0 14.8 6.5 168.9 19.6 32.2 71.6 13.0 15.1 37.8 14.4 4.4 5.7 43.1 14.0 21.9 51.0 29.3 12.7 21.6 37.1 82.7 16.1 23.5 7.3 77.3 12.2 18.5 11.0 32.1 16.8 11.9 16.0 10.3 16.1 7.7 6.2 4.5 5.0 63.0 83.8 42.5 11.4 44.1 92.9 42.9 18.4 5.8 6.6 35.0 35.1 18.7 23.6 21.3 20.2 23.3 7.9 12.4 65.4 36.6 KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 123.3" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 2.4;SK-BR-3: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 3.3 1.4 0.9 0.8 3.1 0.1 2.5 0.8 1.5 1.8 47.1 2.1 2.7 1.2 8.8 1.1 0.8 1.3 1.1 4.2 1.1 128.7 0.4 3.5 1.0 0.5 0.5 0.1 1.2 135.2 0.3 30.4 0.5 8.0 0.9 0.0 0.8 2.5 0.7 0.6 2.6 1.2 0.6 2.4 2.0 0.5 0.8 0.5 1.3 1.5 0.5 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.1 0.8 1.5 4.2 1.1 0.5 0.5 0.5 0.6 0.8 0.5 15.8 0.0 0.5 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.7 12.9 0.0 0.2 0.0 0.4 5.9 0.0 1.8 0.1 2.5 10.2 16.3 0.4 1.2 0.0 0.1 1.6 0.0 0.1 0.0 0.1 1.1 0.2 2.8 0.0 0.5 1.1 0.0 0.9 1.0 0.8 0.3 1.9 0.0 6.5 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.6 1.8 123.3 0.7 0.0 0.0 1.1 2.3 1.4 0.5 0.0 0.1 0.1 1.1 0.1 1.9 0.1 KLB ENSG00000134962 "Klotho beta" Q86Z14 4 39406930-39451533 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 19.6;liver: 17.7;pancreas: 6.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.6;Enteroendocrine cells: 17.4;Hepatocytes: 51.4;Intestinal goblet cells: 12.1;Spermatocytes: 39.5" "Cancer enriched" "Detected in some" 16 "liver cancer: 11.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 24 "ASC diff: 6.7;Hep G2: 25.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021136 Uncertain NA NA 320000 "Cluster 10: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA021136: AB_1852616" "unprognostic (1.03e-2)" "unprognostic (1.61e-2)" "unprognostic (4.67e-2)" "unprognostic (2.69e-1)" "unprognostic (4.30e-2)" "unprognostic (7.02e-3)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (6.99e-3)" "unprognostic (4.51e-3)" "unprognostic (3.02e-3)" "unprognostic (8.90e-3)" "unprognostic (1.73e-1)" "unprognostic (5.03e-2)" "unprognostic (4.53e-2)" "unprognostic (3.87e-2)" "unprognostic (3.09e-2)" 19.6 0.1 0.2 0.2 0.4 0.3 3.5 0.9 0.6 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.2 0.2 0.2 17.7 1.6 0.0 0.3 0.0 0.0 6.0 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.3 2.8 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.3 0.1 0.0 6.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 25.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.2 0.4 0.9 0.6 0.2 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.6 3.2 19.6 0.0 0.7 0.5 1.1 1.4 0.0 1.6 0.7 1.1 1.2 0.0 1.2 0.0 0.0 0.4 0.5 1.6 0.0 1.1 8.5 4.4 1.5 0.4 17.4 0.0 0.5 4.3 1.5 0.5 2.6 2.2 0.0 0.2 0.4 51.4 0.2 1.7 0.6 12.1 2.0 1.0 0.6 3.2 1.5 0.4 1.8 0.0 0.1 0.4 0.0 0.5 0.2 0.9 4.8 0.7 0.0 1.2 2.1 1.1 0.4 2.3 0.0 1.2 0.5 39.5 0.9 2.0 0.9 1.4 0.8 0.5 1.1 1.1 KLF11 "MODY7, TIEG2, Tieg3" ENSG00000172059 "Kruppel like factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Suprabasal keratinocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: AB_2683664" "unprognostic (9.66e-3)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-3)" "unprognostic (2.63e-3)" "unprognostic (6.34e-2)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (3.08e-2)" "unprognostic (2.48e-3)" "unprognostic (8.96e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-2)" "unprognostic (9.24e-2)" 27.7 15.6 4.0 7.6 3.2 27.8 22.3 8.3 3.9 13.5 4.1 17.9 7.5 20.0 9.7 13.2 13.7 18.1 19.1 2.9 3.9 15.7 35.2 22.4 9.3 3.7 3.3 23.9 54.2 18.3 2.5 19.5 3.4 10.1 9.3 3.0 15.9 14.8 12.1 26.9 8.7 16.8 3.2 18.8 12.4 30.0 3.5 4.0 16.5 27.3 5.5 12.6 13.1 5.1 6.9 3.3 7.8 0.7 5.3 9.4 18.8 7.9 7.9 4.4 4.6 7.8 15.8 0.0 13.9 9.6 17.9 1.6 6.8 6.1 2.9 47.6 5.2 3.5 9.7 1.6 5.2 14.6 22.1 14.7 22.3 8.4 2.3 11.4 3.9 1.3 9.7 30.8 4.6 8.2 0.0 2.7 12.5 5.6 6.7 7.8 0.2 13.6 10.8 8.5 10.0 6.2 12.0 24.5 23.4 12.2 5.7 19.6 11.2 19.3 15.9 14.7 2.6 27.9 36.0 18.7 5.0 3.8 10.4 0.0 8.2 2.0 2.6 12.3 0.8 3.2 1.8 1.9 7.3 2.9 0.5 1.1 0.2 6.6 14.8 0.3 3.0 5.4 4.0 3.2 8.3 3.9 2.9 3.9 3.7 3.3 3.4 3.2 3.5 5.1 58.8 6.4 4.6 0.3 12.5 60.5 17.7 5.5 25.6 6.2 14.3 13.2 3.5 10.0 6.1 7.3 6.2 3.2 10.1 2.5 29.4 8.2 135.0 9.1 21.5 33.3 7.1 4.6 1.7 8.5 4.2 17.5 9.7 26.6 8.2 15.5 37.5 38.1 12.5 3.3 1.4 7.0 16.2 32.4 42.4 25.9 14.6 22.0 30.2 1.0 16.6 2.2 3.1 0.5 0.3 8.9 1.5 16.6 5.3 15.0 6.1 8.4 4.3 5.8 32.9 10.4 35.7 13.8 39.0 13.1 86.2 8.2 10.8 11.2 7.8 11.7 KLF14 BTEB5 ENSG00000266265 "Kruppel like factor 14" Q8TD94 7 130730697-130734207 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.1;testis: 1.0" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 1.8;Early spermatids: 4.1;Late spermatids: 4.1" "Cancer enriched" "Detected in single" 6 "melanoma: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.0;RH-30: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA044729 Uncertain NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" "HPA044729: AB_10960356" "unprognostic (4.49e-2)" "unprognostic (2.62e-1)" "unprognostic (2.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.92e-1)" "unprognostic (9.90e-3)" "unprognostic (7.98e-2)" "unprognostic (5.30e-3)" "unprognostic (7.14e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (7.03e-3)" "unprognostic (3.63e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" 0.6 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.4 0.0 1.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.4 0.0 0.0 KLF15 KKLF ENSG00000163884 "Kruppel like factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cardiomyocytes: 29.7;Distal tubular cells: 29.4;Hepatocytes: 66.9;Peritubular cells: 19.9;Proximal tubular cells: 22.1" "Cancer enhanced" "Detected in many" "liver cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 57.4;HHSteC: 34.8;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: AB_10600819" "unprognostic (3.77e-3)" "unprognostic (1.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-3)" "unprognostic (2.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-2)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "prognostic favorable (3.27e-7)" "unprognostic (6.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.91e-2)" "unprognostic (5.58e-3)" 36.5 6.2 42.2 0.8 50.7 0.1 25.4 45.1 69.5 15.8 37.5 18.6 1.2 19.1 4.1 7.1 29.7 3.5 31.4 41.7 40.6 20.3 92.5 18.6 1.8 64.9 45.9 46.3 48.5 4.5 10.4 1.7 47.2 17.6 0.9 3.9 19.7 5.2 67.3 10.3 10.2 2.5 44.9 3.6 30.2 5.6 44.7 1.2 11.1 32.4 0.8 27.0 12.0 48.4 0.8 0.0 2.2 9.2 57.4 1.0 10.0 0.6 1.4 0.7 1.3 1.1 0.0 3.4 0.9 0.0 1.7 0.1 5.3 0.1 0.2 0.2 2.0 0.1 0.8 7.9 34.8 0.0 0.2 5.4 0.5 0.0 1.2 0.0 0.6 4.5 4.3 7.4 0.2 0.7 0.0 1.3 6.6 1.3 0.3 4.7 0.2 20.2 0.1 0.8 0.7 7.7 0.1 0.3 10.2 3.3 0.5 4.6 0.3 0.3 0.4 0.3 0.3 4.7 0.6 0.7 0.2 1.5 1.3 25.1 7.6 10.3 7.0 10.2 8.2 12.3 7.3 7.4 8.2 11.4 9.4 11.3 16.7 12.8 9.3 9.0 10.5 11.7 42.2 50.7 45.1 69.5 41.7 40.6 64.9 45.9 47.2 44.9 44.7 48.4 1.5 6.4 4.6 22.9 0.8 0.0 2.9 0.2 0.6 1.3 7.8 1.8 29.7 15.7 0.7 0.0 0.0 0.1 0.1 0.0 29.4 0.1 0.1 2.5 4.4 2.1 0.0 2.7 0.6 0.0 0.2 8.1 3.1 3.4 0.0 13.7 8.2 66.9 0.1 0.0 2.8 0.1 0.0 2.6 0.0 0.8 12.2 0.4 1.8 2.8 0.0 12.0 0.0 15.1 5.7 0.4 0.0 19.9 0.9 5.2 0.0 22.1 0.8 3.3 0.0 12.0 5.5 0.1 0.1 0.3 0.0 0.3 0.5 0.6 0.1 1.8 KLF4 "EZF, GKLF" ENSG00000136826 "Kruppel like factor 4" O43474 9 107484852-107490482 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 254.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1054.7;Basal squamous epithelial cells: 832.1;Distal enterocytes: 789.2;Intestinal goblet cells: 710.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.0;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.2;hTCEpi: 84.4;hTERT-HME1: 54.5;OE19: 47.2;U-2197: 111.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002926 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA002926: AB_1852541" "unprognostic (2.06e-1)" "unprognostic (1.42e-2)" "unprognostic (1.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-3)" "unprognostic (3.44e-2)" "unprognostic (6.49e-2)" "unprognostic (3.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "prognostic favorable (3.93e-5)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (8.13e-2)" "unprognostic (8.32e-2)" 73.5 23.9 5.1 21.0 4.7 50.5 63.7 4.0 7.8 53.2 4.6 87.3 28.4 16.0 5.6 102.1 43.0 44.3 31.0 3.7 5.1 6.2 12.4 44.8 5.6 5.0 4.7 29.0 7.0 5.7 4.9 32.4 5.0 16.7 96.0 0.8 27.5 7.6 14.2 254.7 40.5 40.6 4.1 24.1 58.0 17.8 6.0 17.0 25.2 23.2 14.5 43.9 58.9 4.0 13.3 3.9 0.6 0.1 16.6 39.2 5.2 4.4 27.6 6.7 8.1 1.0 18.0 0.0 0.6 6.9 23.7 8.7 6.1 3.9 3.0 0.0 2.2 0.0 7.5 0.3 21.6 0.0 0.0 5.0 84.4 14.0 54.5 1.5 0.6 0.2 0.6 0.0 4.1 7.3 0.0 1.4 4.1 47.2 25.2 0.3 1.6 0.2 2.3 3.7 0.4 0.2 4.0 11.8 15.2 12.7 1.3 5.4 3.5 3.6 0.1 111.5 2.1 0.2 0.1 0.0 3.4 2.6 6.8 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 1.0 0.2 0.0 0.1 5.1 4.7 4.0 7.8 3.7 5.1 5.0 4.7 5.0 4.1 6.0 4.0 1054.7 12.8 41.1 0.3 32.2 436.0 284.3 143.0 832.1 0.5 206.7 205.0 70.3 35.8 71.5 1.8 8.4 49.1 15.0 789.2 1.9 24.4 263.1 154.1 216.0 336.6 123.8 4.8 0.0 38.7 75.5 463.2 537.2 297.4 54.7 4.7 216.0 4.6 89.9 0.0 0.2 710.9 83.4 232.9 282.0 163.0 143.8 401.0 206.3 16.9 36.8 2.0 0.0 0.0 0.0 49.3 540.9 60.5 38.3 187.3 198.0 2.1 46.4 2.0 39.5 463.7 130.0 21.6 15.9 639.9 674.0 107.9 26.8 63.5 332.6 236.8 KLHDC8B MGC35097 ENSG00000185909 "Kelch domain containing 8B" Q8IXV7 3 49171598-49176486 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 128.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 60.7;Sertoli cells: 98.6;Theca cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 28.8" "Group enriched" "Detected in many" 10 "granulocytes: 28.8;monocytes: 8.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008463, HPA014467" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol "HPA008463: AB_1852563, HPA014467: AB_1852565" "unprognostic (1.66e-2)" "unprognostic (1.42e-1)" "unprognostic (5.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.66e-1)" "unprognostic (5.03e-3)" "unprognostic (1.71e-3)" "prognostic favorable (1.47e-4)" "unprognostic (6.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (4.30e-2)" "unprognostic (1.02e-3)" "unprognostic (4.78e-2)" "unprognostic (5.60e-2)" "unprognostic (1.86e-2)" "unprognostic (1.61e-2)" 29.1 128.7 13.5 5.6 14.0 6.1 24.9 9.4 14.8 20.2 24.8 56.1 7.2 26.2 10.6 31.1 26.5 16.7 70.5 12.4 21.2 16.3 12.6 17.3 9.9 12.4 14.2 70.1 9.4 10.4 10.1 12.3 16.1 16.9 3.6 2.3 14.1 13.5 29.6 28.1 14.0 14.2 11.6 13.2 16.7 15.5 19.1 4.3 26.6 13.4 6.8 29.4 22.5 10.3 2.5 5.5 22.4 11.4 13.5 8.0 6.9 8.4 4.7 8.2 6.6 3.6 7.4 0.0 4.6 14.0 2.3 0.1 5.6 5.1 2.1 4.6 1.5 15.1 15.2 9.6 25.6 0.0 8.5 13.3 23.9 10.6 0.8 18.4 21.2 5.3 23.7 0.2 6.3 0.7 1.6 16.7 7.4 1.3 13.1 2.3 2.1 0.7 6.1 1.3 0.9 25.2 6.7 0.2 17.0 4.7 6.8 7.3 9.3 6.2 17.1 11.2 2.6 2.1 0.7 0.3 4.5 0.0 3.1 0.0 5.4 28.8 1.0 8.0 0.4 0.0 0.5 0.7 0.5 0.1 1.8 1.0 9.7 0.0 8.3 0.8 0.2 2.4 13.5 14.0 9.4 14.8 12.4 21.2 12.4 14.2 16.1 11.6 19.1 10.3 14.1 9.6 10.9 5.9 0.9 7.6 11.5 16.4 10.8 2.2 10.8 9.0 60.7 11.5 14.3 7.3 2.1 10.9 2.4 1.0 17.6 14.3 7.2 6.8 6.9 20.5 6.7 6.5 3.8 5.9 8.5 22.3 2.6 3.3 1.3 7.7 37.1 7.5 41.7 0.0 4.6 3.0 18.3 12.0 2.2 7.7 15.2 10.5 12.4 6.5 2.5 29.4 0.0 3.5 0.7 8.6 1.7 14.3 0.6 8.3 0.7 13.4 4.0 2.7 98.6 28.3 31.1 9.2 8.6 15.5 9.8 49.8 1.5 55.5 1.7 7.9 KLHL31 "bA345L23.2, BKLHD6, KBTBD1" ENSG00000124743 "Kelch like family member 31" Q9H511 6 53647916-53665756 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 51.3;skeletal muscle: 146.1;tongue: 34.8" "Cell type enriched" "Detected in some" 33 "Cardiomyocytes: 248.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (7.27e-2)" "unprognostic (6.18e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-1)" "unprognostic (7.67e-4)" "unprognostic (2.23e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-1)" "unprognostic (3.98e-2)" "unprognostic (5.50e-2)" "unprognostic (4.24e-1)" "unprognostic (1.09e-4)" "unprognostic (8.73e-2)" "unprognostic (2.88e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" 8.6 0.8 0.2 0.2 0.5 0.0 3.1 0.2 0.3 0.2 0.7 0.2 0.4 0.2 0.8 0.7 0.8 0.2 51.3 0.1 0.3 0.2 0.4 0.2 0.1 0.3 0.2 0.3 0.4 0.0 0.4 0.1 0.3 1.3 0.2 0.4 1.2 0.1 146.1 1.3 0.3 0.0 0.3 0.1 0.3 0.3 0.3 0.1 0.9 34.8 0.2 0.3 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.0 0.3 0.1 0.6 0.4 0.0 0.1 0.0 0.5 0.7 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.2 0.0 0.8 0.0 0.2 0.2 1.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.1 0.3 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.0 0.0 0.7 0.0 0.6 0.8 0.7 0.0 0.5 0.9 0.9 248.9 0.0 0.5 0.0 0.0 1.0 0.1 0.6 0.0 0.1 0.4 2.0 0.3 1.7 0.0 3.2 0.2 0.4 0.2 7.5 0.5 3.1 0.0 0.9 0.0 0.2 0.2 0.0 0.2 0.1 2.0 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.5 0.0 0.2 0.0 0.1 0.6 0.0 0.2 0.2 0.1 0.0 3.7 2.2 0.0 0.2 0.0 0.4 0.8 0.3 0.4 0.3 0.4 KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 186.3;Microglial cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 323.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" 41.4 22.4 53.9 32.3 53.8 9.0 18.7 44.8 56.5 17.0 29.4 44.4 12.7 19.1 13.5 32.0 9.4 23.1 14.4 49.8 50.0 25.0 42.3 20.2 33.7 53.5 50.2 18.4 11.3 12.9 7.5 28.0 53.0 35.9 16.1 11.8 10.2 66.0 10.7 6.1 13.2 46.1 56.7 21.0 13.1 11.0 55.2 14.6 21.5 18.9 38.9 34.8 9.5 52.6 56.7 78.2 40.9 30.2 22.9 58.5 59.1 44.2 323.1 36.6 35.4 64.6 40.4 86.4 52.4 45.5 192.7 3.3 50.7 112.3 46.6 8.8 10.1 36.8 71.4 46.5 195.6 10.9 11.9 74.5 61.9 55.5 137.7 134.1 73.7 13.8 28.2 17.0 87.1 23.8 11.5 19.6 12.6 14.3 75.5 20.9 53.7 2.1 31.3 23.0 2.8 29.7 25.0 8.0 21.8 49.0 19.3 22.9 94.2 96.8 65.4 25.5 53.8 19.3 18.7 79.0 78.6 28.3 22.9 5.4 2.2 0.4 0.7 3.2 1.1 5.1 1.4 0.8 2.5 3.7 1.1 0.5 2.3 1.0 1.4 0.9 0.2 0.8 53.9 53.8 44.8 56.5 49.8 50.0 53.5 50.2 53.0 56.7 55.2 52.6 74.9 16.0 1.1 45.7 38.0 3.7 9.4 22.9 7.4 18.8 16.5 11.2 4.5 17.2 33.7 11.0 4.2 1.0 6.3 0.3 17.6 39.3 2.8 4.0 11.1 43.6 1.2 10.9 46.1 21.0 57.9 12.6 3.1 5.3 2.5 9.5 22.9 35.6 13.3 70.7 186.3 0.4 12.2 25.4 25.8 6.6 8.1 28.6 17.8 190.2 27.5 12.1 7.2 69.9 79.0 24.3 0.1 13.9 43.0 31.5 2.0 21.8 32.7 3.4 0.0 14.2 17.3 9.8 5.6 3.3 3.4 5.7 10.7 32.4 0.7 14.1 KRT79 "K6L, KRT6L" ENSG00000185640 "Keratin 79" Q5XKE5 12 52821408-52834311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 68.3" "Cell type enhanced" "Detected in some" "granulocytes: 4.5;Late spermatids: 1.1;Melanocytes: 3.6" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;cervical cancer: 2.6;head and neck cancer: 2.7;melanoma: 1.6;urothelial cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HMC-1: 425.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059347 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA 1900000000 "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Nuclear membrane, Cytosol" "HPA059347: AB_2683986" "unprognostic (5.19e-3)" "unprognostic (1.56e-3)" "unprognostic (5.24e-2)" "unprognostic (2.38e-2)" "unprognostic (6.85e-2)" "unprognostic (6.36e-2)" "unprognostic (3.17e-1)" "unprognostic (7.92e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (3.99e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 425.5 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062236 Enhanced Supported "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" 28.6 9.1 8.8 53.2 9.7 95.7 17.1 9.3 11.9 27.3 9.2 61.4 40.7 47.0 44.4 29.7 31.8 21.7 10.0 8.5 10.1 19.4 47.3 19.2 81.6 12.0 9.8 19.4 16.9 5.6 6.5 27.6 11.2 23.8 46.2 5.3 11.1 36.7 9.8 13.8 39.9 41.4 10.2 41.5 28.2 20.5 9.5 105.5 11.8 12.8 70.7 32.3 23.0 13.1 122.2 42.0 154.9 69.3 64.8 39.7 77.3 31.2 39.2 65.0 69.0 87.2 207.2 248.4 66.6 32.8 38.6 88.8 114.2 32.9 98.5 142.2 107.1 61.4 40.4 81.5 39.9 274.7 105.5 34.3 21.3 58.9 52.0 33.1 82.9 117.4 189.6 164.6 44.4 16.3 254.9 156.6 140.6 121.8 14.2 164.9 141.4 234.0 75.6 52.7 40.6 53.4 52.7 39.6 26.6 68.2 53.3 181.0 50.5 17.6 91.7 49.3 115.9 56.6 83.0 274.5 24.3 120.5 61.2 83.6 44.3 67.3 43.6 31.6 50.9 39.0 43.5 48.8 38.4 39.5 42.4 52.9 211.4 41.3 25.2 21.5 61.9 69.8 8.8 9.7 9.3 11.9 8.5 10.1 12.0 9.8 11.2 10.2 9.5 13.1 98.1 28.9 36.4 13.4 86.4 27.0 33.4 17.3 21.6 4.5 11.9 11.0 8.5 48.6 34.4 31.3 6.2 40.5 98.3 33.4 5.9 23.6 1.2 31.5 31.0 53.1 27.0 248.9 10.5 19.8 23.9 29.0 29.0 53.9 10.1 24.0 48.5 73.6 44.4 11.8 14.3 43.0 12.2 88.5 18.1 3.4 33.8 71.7 26.6 19.7 56.0 11.6 82.4 37.2 34.1 20.6 24.6 32.4 74.0 32.9 19.3 26.0 26.0 10.4 39.5 13.9 46.6 21.0 26.7 68.4 35.5 11.1 81.3 13.2 73.8 36.7 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LDHB ENSG00000111716 "Lactate dehydrogenase B" P07195 12 21635342-21757857 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1947.7;kidney: 1726.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2502.3;Cytotrophoblasts: 1693.0;Distal tubular cells: 3306.5;Proximal tubular cells: 3483.9;Syncytiotrophoblasts: 1639.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 6021.8" "CAB004641, HPA019007" Enhanced Supported Cytosol No No 560000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB004641: AB_425525, HPA019007: AB_2670008" "unprognostic (2.93e-1)" "unprognostic (9.20e-3)" "unprognostic (6.10e-2)" "unprognostic (1.11e-1)" "unprognostic (5.39e-3)" "unprognostic (1.36e-3)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (5.34e-2)" "unprognostic (8.40e-2)" "unprognostic (2.91e-1)" "unprognostic (6.41e-2)" "prognostic favorable (2.51e-4)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (2.55e-1)" "unprognostic (9.32e-2)" 549.9 424.8 509.1 259.2 528.2 352.8 321.1 593.7 617.0 238.6 549.8 320.2 84.4 273.1 169.0 166.6 252.9 232.9 1947.7 484.1 581.9 1726.6 70.5 220.4 425.8 564.4 575.4 472.4 370.3 447.3 161.3 298.2 556.2 240.9 277.0 290.0 162.3 287.2 309.4 81.4 171.3 309.7 537.8 182.0 459.1 119.5 582.5 534.5 348.5 950.4 449.4 417.9 171.2 517.8 647.2 1697.3 1457.5 966.0 1021.7 1126.6 1689.4 879.8 873.0 1201.5 1179.4 2712.9 3.6 2268.6 561.5 597.3 1170.1 315.8 2031.4 1631.4 1518.4 586.5 1413.1 2339.5 1619.0 3.0 975.0 2212.8 967.9 1300.5 572.1 1056.8 1423.4 1416.9 1395.2 1610.8 1304.6 332.6 1342.7 3.2 1895.9 2665.6 4216.4 1051.1 727.7 1681.3 2032.0 1838.7 6021.8 2832.7 467.2 1077.8 403.6 618.1 1586.1 3842.2 5.3 1704.6 548.3 803.7 1048.1 578.5 1684.5 291.0 420.9 2953.4 891.8 1037.5 978.2 540.8 201.9 25.1 346.8 124.7 583.1 349.4 1341.5 723.8 367.2 250.9 1722.4 1124.1 31.7 459.0 95.2 427.7 1405.8 1431.2 509.1 528.2 593.7 617.0 484.1 581.9 564.4 575.4 556.2 537.8 582.5 517.8 89.8 141.1 316.4 68.2 242.2 73.0 439.5 1103.1 221.4 151.5 332.4 325.0 2502.3 298.8 433.9 474.5 68.8 1693.0 208.0 69.6 3306.5 18.4 10.5 224.3 325.0 227.3 92.4 361.2 39.4 314.9 870.1 299.4 222.8 309.4 268.6 412.6 155.7 11.2 612.9 141.3 55.6 152.2 956.2 189.8 104.3 34.3 274.6 174.8 179.7 33.7 197.3 277.6 159.6 47.7 40.3 99.7 84.3 415.2 303.1 310.6 0.2 3483.9 363.0 118.1 236.7 195.2 363.7 21.5 124.3 216.3 64.2 1639.5 398.1 1105.3 257.0 344.9 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;liver: 135.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1" "Cancer enhanced" "Detected in all" "liver cancer: 32.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.1" "Group enriched" "Detected in many" 45 "granulocytes: 11.1;monocytes: 4.8" "Cell line enhanced" "Detected in many" "Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol No NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626" "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favorable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 24.9 14.4 17.7 2.1 19.7 0.7 11.7 20.5 22.6 5.4 34.1 27.2 8.8 3.5 1.1 10.8 5.5 3.0 85.6 16.1 18.9 36.1 135.5 4.9 0.8 20.8 20.2 16.4 18.7 17.0 11.8 0.7 22.4 8.1 9.7 1.3 21.3 3.2 68.7 5.8 5.7 1.2 17.0 1.1 23.1 1.7 19.3 0.5 10.6 52.7 0.6 2.6 3.7 17.5 0.7 2.1 0.0 0.2 1.6 1.4 6.1 0.2 0.1 0.2 0.2 2.8 2.6 0.1 2.1 0.9 1.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.8 11.4 2.6 0.0 14.4 2.0 0.3 0.0 0.0 0.6 0.1 0.4 0.7 2.5 0.0 5.3 0.1 0.8 1.4 2.7 1.3 0.0 0.0 7.8 1.4 0.1 0.0 0.0 0.2 5.2 0.3 0.7 29.1 3.3 0.0 0.0 0.2 0.0 0.0 11.5 0.6 0.0 1.9 0.1 0.0 11.1 2.2 0.6 0.0 3.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 17.7 19.7 20.5 22.6 16.1 18.9 20.8 20.2 22.4 17.0 19.3 17.5 1.6 0.0 6.7 7.8 1.0 0.6 1.8 2.2 0.6 0.5 6.5 2.4 37.3 11.5 2.3 11.0 0.0 2.1 0.1 80.2 37.2 2.3 0.4 2.2 0.3 1.7 3.0 2.7 1.0 6.2 1.2 2.3 32.6 3.8 10.2 2.1 4.2 88.6 7.2 1.7 1.4 11.0 0.0 6.0 1.0 0.6 0.0 3.0 5.4 1.9 2.0 12.0 0.0 1.0 3.2 3.0 28.3 0.0 0.8 2.1 2.4 118.1 2.0 1.4 0.0 4.1 1.3 0.0 0.7 3.6 0.3 3.1 1.0 1.8 15.7 1.5 LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 307.5;breast: 90.1" "Group enriched" "Detected in some" 44 "Extravillous trophoblasts: 124.2;Syncytiotrophoblasts: 432.2" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB010490 Approved "Secreted to blood" NA NA 17000000 19000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010490: AB_2296951" "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" 307.5 0.8 0.1 5.0 0.1 0.1 90.1 0.5 0.3 0.1 0.1 2.0 0.1 0.0 0.0 0.2 0.1 1.2 1.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 2.4 0.0 0.0 4.6 0.1 0.0 0.4 0.0 1.1 0.0 0.7 3.9 1.2 0.1 0.0 0.2 0.5 0.2 0.1 0.3 0.2 1.2 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.8 0.1 0.6 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 124.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.1 432.2 0.1 0.1 0.0 0.1 LGALS12 GRIP1 ENSG00000133317 "Galectin 12" Q96DT0 11 63506052-63516774 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 78.3;breast: 41.3" "Cell type enhanced" "Detected in some" "granulocytes: 17.8;Macrophages: 13.3;monocytes: 2.5;Muller glia cells: 3.9" "Cancer enhanced" "Detected in some" "renal cancer: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 20 "eosinophil: 554.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 554.9" "Group enriched" "Detected in some" 14 "ASC diff: 28.9;HL-60: 53.0;NB-4: 109.4;U-937: 112.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA021124 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA021124: " "unprognostic (3.89e-2)" "unprognostic (4.40e-2)" "unprognostic (5.17e-2)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "unprognostic (4.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-3)" "unprognostic (4.69e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (4.60e-7)" "unprognostic (2.72e-3)" "unprognostic (1.19e-1)" "unprognostic (6.22e-2)" "unprognostic (8.60e-2)" 78.3 0.8 0.1 2.7 0.2 18.4 41.3 0.1 0.2 0.1 0.4 0.9 0.5 0.2 0.0 0.2 1.0 1.7 2.1 0.1 0.2 0.3 0.3 1.0 0.1 0.2 0.2 0.2 0.6 0.0 0.0 0.1 0.2 0.4 0.6 1.9 4.5 0.7 0.5 1.0 2.0 1.0 0.2 1.1 0.9 0.0 0.1 0.3 0.7 1.4 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.0 28.9 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.8 53.0 3.3 3.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 109.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 5.3 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 112.2 0.0 15.5 28.1 554.9 0.2 3.3 0.2 0.0 0.0 0.0 7.5 0.1 0.1 0.1 5.7 0.2 0.5 0.7 0.3 17.3 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 1.1 0.1 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 13.3 0.0 0.0 2.5 3.9 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 LHFPL6 "LHFP, MGC22429" ENSG00000183722 "LHFPL tetraspan subfamily member 6" Q9Y693 13 39209116-39603528 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 195.2;Endometrial stromal cells: 78.1;Extravillous trophoblasts: 156.9;Fibroblasts: 113.0;Smooth muscle cells: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "myeloid DC: 6.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.2" "Cell line enhanced" "Detected in many" "ASC diff: 255.1;HSkMC: 186.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058975 Approved Approved Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA058975: AB_2683866" "unprognostic (6.98e-2)" "unprognostic (2.71e-1)" "unprognostic (2.00e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (4.10e-2)" "unprognostic (5.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.76e-1)" "unprognostic (5.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (4.41e-3)" "unprognostic (5.25e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (2.30e-4)" 143.2 55.1 46.3 18.6 49.9 1.1 128.7 59.2 45.2 51.6 57.2 51.7 10.8 78.8 47.5 37.0 88.9 74.5 99.7 45.6 57.3 31.9 14.2 82.6 39.1 54.9 56.8 49.6 17.2 18.2 26.9 134.6 51.4 30.8 16.7 11.9 34.7 36.9 32.1 37.9 29.0 68.9 47.8 30.4 27.9 20.4 64.3 17.0 64.2 89.2 17.6 49.1 48.3 44.3 11.5 4.0 118.3 5.1 255.1 115.1 51.6 61.8 88.3 30.8 23.1 0.5 11.6 17.5 1.3 86.6 40.0 17.3 15.0 36.2 25.3 16.9 17.2 47.3 3.7 0.0 26.7 0.8 0.9 186.4 4.7 27.7 45.7 27.6 29.1 1.1 0.0 0.1 59.9 9.9 0.0 14.5 8.8 0.2 15.8 7.7 51.3 0.1 20.9 15.0 0.7 3.8 5.6 7.2 16.8 67.4 6.7 0.1 54.3 77.9 11.7 24.4 33.9 0.9 0.0 48.9 32.4 0.2 57.2 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.3 46.3 49.9 59.2 45.2 45.6 57.3 54.9 56.8 51.4 47.8 64.3 44.3 195.2 3.2 12.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.4 28.6 0.0 0.0 9.9 0.0 0.0 5.0 1.4 0.0 1.9 0.6 0.0 2.7 78.1 32.0 0.0 0.0 0.0 0.6 156.9 113.0 0.0 2.8 2.5 22.1 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 3.6 2.2 0.0 0.0 0.0 131.6 0.0 0.0 0.0 0.0 6.2 1.2 45.8 0.0 0.0 LILRB2 "CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10" ENSG00000131042 "Leukocyte immunoglobulin like receptor B2" Q8N423 19 54273812-54281184 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 35.0;lung: 15.0;lymphoid tissue: 51.2" "Cell type enhanced" "Detected in some" "Kupffer cells: 150.7;Langerhans cells: 61.8;Macrophages: 147.3;monocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "classical monocyte: 61.6;intermediate monocyte: 132.3;neutrophil: 62.9;non-classical monocyte: 153.4" "Group enriched" "Detected in many" 6 "granulocytes: 62.9;monocytes: 153.4" "Not detected" "Not detected" NA NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.23e-1)" "unprognostic (1.12e-2)" "unprognostic (3.21e-2)" "unprognostic (3.51e-2)" "unprognostic (6.21e-3)" "unprognostic (1.70e-2)" "unprognostic (1.44e-2)" "unprognostic (2.94e-1)" "unprognostic (1.08e-2)" "unprognostic (2.98e-2)" "unprognostic (2.64e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.45e-7)" "unprognostic (1.90e-2)" "unprognostic (4.68e-3)" "unprognostic (3.72e-1)" "unprognostic (9.73e-2)" 6.5 2.6 0.0 12.2 0.0 35.0 2.2 0.0 0.5 1.1 0.6 2.3 3.2 1.2 0.1 1.0 3.7 0.0 2.5 0.1 0.1 2.2 3.9 15.0 0.8 0.9 0.5 0.8 1.3 0.0 1.3 0.5 0.6 1.7 0.8 0.0 1.6 0.4 0.6 0.6 3.0 0.4 0.0 51.2 1.8 0.3 1.0 0.2 1.1 0.1 0.0 2.3 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.0 61.6 16.2 0.1 132.3 0.3 0.0 0.0 0.0 18.8 0.1 0.1 0.0 62.9 0.0 153.4 8.0 0.3 29.7 0.0 0.0 0.0 0.5 0.1 0.1 0.9 0.5 0.6 0.0 1.0 0.2 0.5 3.2 10.9 0.0 5.5 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 1.5 3.1 0.0 0.0 0.1 10.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.8 0.0 0.0 0.3 1.0 1.1 0.0 5.1 0.0 2.2 1.5 27.2 0.0 0.0 0.0 0.0 150.7 61.8 0.1 0.0 147.3 3.6 1.0 75.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.3 2.2 0.0 6.6 0.4 0.2 0.0 0.0 0.0 0.6 0.1 2.9 0.0 0.0 0.1 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 LIMD2 MGC10986 ENSG00000136490 "LIM domain containing 2" Q9BT23 17 63695888-63701172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 112.1;lymphoid tissue: 222.2" "Cell type enhanced" "Detected in many" "B-cells: 436.9;dendritic cells: 306.6;Kupffer cells: 216.1;monocytes: 188.2;NK-cells: 510.9;T-cells: 264.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 243.0;NB-4: 171.7;SH-SY5Y: 163.3;THP-1: 127.6;U-698: 260.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062432, HPA075172" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA062432: , HPA075172: " "unprognostic (2.90e-3)" "unprognostic (2.89e-3)" "unprognostic (6.34e-2)" "unprognostic (6.53e-2)" "unprognostic (8.72e-2)" "unprognostic (2.00e-3)" "unprognostic (1.81e-1)" "unprognostic (2.67e-2)" "unprognostic (6.68e-2)" "unprognostic (2.01e-2)" "unprognostic (1.20e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.36e-11)" "unprognostic (1.21e-1)" "unprognostic (2.21e-1)" "unprognostic (2.26e-2)" "unprognostic (6.08e-2)" 12.5 7.9 26.2 106.9 31.3 112.1 8.2 18.8 35.4 12.1 19.1 11.2 13.6 7.8 2.0 6.4 8.9 17.5 9.8 29.9 22.6 17.3 10.4 24.8 222.2 22.9 22.1 7.1 7.1 3.3 10.7 15.5 22.3 16.3 9.4 1.0 12.9 5.5 3.1 6.7 61.0 9.1 21.8 170.8 20.5 14.0 22.8 111.3 9.3 3.4 149.8 20.3 8.2 23.7 0.8 7.7 92.9 22.9 0.8 2.4 2.3 2.6 1.4 9.4 6.4 4.2 1.9 243.0 20.5 11.6 9.4 3.9 20.4 0.9 2.6 84.3 8.7 72.4 1.8 20.6 17.6 95.2 7.6 22.8 1.0 9.6 0.3 11.0 25.5 16.5 6.7 13.8 10.7 1.3 84.7 171.7 50.3 0.0 4.4 34.6 37.4 43.6 13.1 1.0 111.2 163.3 11.8 0.2 22.2 23.9 0.6 127.6 32.2 12.8 28.1 0.7 3.4 2.9 1.0 260.4 1.4 13.3 22.7 2144.2 601.8 1434.7 368.9 716.3 364.8 688.5 512.2 432.9 609.8 855.0 679.3 496.3 1248.9 553.2 783.9 230.5 664.2 991.4 26.2 31.3 18.8 35.4 29.9 22.6 22.9 22.1 22.3 21.8 22.8 23.7 11.0 0.0 4.6 0.7 436.9 7.5 7.7 20.5 2.2 1.9 5.0 7.2 1.0 4.3 8.6 11.0 4.2 1.6 306.6 1.1 5.9 20.5 18.8 2.3 14.2 23.6 22.2 99.2 18.7 8.9 3.6 10.1 5.6 4.2 53.3 15.7 30.4 2.0 137.6 3.3 2.2 2.1 26.4 216.1 93.9 57.5 3.4 148.0 37.4 12.2 188.2 8.4 510.9 3.5 2.9 19.8 4.7 4.9 154.3 17.7 0.4 3.7 2.4 1.1 6.6 2.9 30.5 7.8 7.5 1.1 6.0 1.5 264.3 4.7 2.5 4.3 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 78.0;Endothelial cells: 88.3;Extravillous trophoblasts: 164.2;Hepatic stellate cells: 95.3;Sertoli cells: 39.5;Smooth muscle cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in some" 6 "ASC diff: 115.0;ASC TERT1: 70.3;HSkMC: 44.0;HUVEC TERT2: 51.4;U-2197: 108.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" NA NA 98000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" 104.5 34.3 12.6 10.5 12.6 2.4 63.6 11.2 11.8 56.2 8.4 23.2 8.9 36.4 6.2 10.3 31.6 29.0 55.7 9.6 10.6 64.7 11.3 109.0 4.3 12.2 13.8 13.5 12.0 7.5 16.7 53.0 13.0 24.9 6.1 1.3 12.8 11.0 23.6 26.6 21.4 15.2 10.9 28.9 21.3 3.6 15.0 2.0 42.3 6.2 1.5 36.7 28.8 11.5 0.0 0.0 1.3 0.0 115.0 70.3 1.4 0.4 0.8 0.1 0.1 0.0 0.0 0.2 3.1 1.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 11.8 0.6 0.0 2.2 0.0 0.1 44.0 0.0 4.1 0.2 0.9 51.4 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 7.6 0.2 0.0 13.8 7.5 0.8 108.3 0.0 0.1 0.0 1.9 5.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 4.3 12.6 12.6 11.2 11.8 9.6 10.6 12.2 13.8 13.0 10.9 15.0 11.5 78.0 0.0 4.3 0.0 1.7 14.5 0.3 0.0 1.8 0.0 0.6 0.6 10.4 0.0 1.3 0.0 0.0 1.9 0.1 0.2 0.0 0.3 1.3 0.1 1.9 88.3 0.0 5.3 0.0 0.0 164.2 26.4 0.5 0.3 2.5 0.5 95.3 0.6 3.6 0.0 0.1 0.4 0.0 3.1 19.0 1.9 9.0 2.9 17.8 14.0 0.0 0.4 0.0 0.0 0.1 0.0 2.2 9.1 0.2 1.4 0.0 0.4 0.7 0.1 39.5 2.1 47.6 0.4 4.7 0.6 12.5 8.3 1.6 0.4 0.1 1.2 LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 73.5;Excitatory neurons: 73.6;Inhibitory neurons: 99.2;Microglial cells: 185.5;Oligodendrocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.9;monocytes: 6.6;T-cells: 11.3" "Cell line enhanced" "Detected in many" "THP-1: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Approved "Golgi apparatus" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 28: Placenta - Pregnancy" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA029347: AB_10601544" "unprognostic (2.61e-2)" "unprognostic (3.09e-2)" "unprognostic (3.83e-2)" "unprognostic (1.76e-2)" "unprognostic (3.32e-2)" "unprognostic (1.65e-2)" "unprognostic (5.02e-2)" "unprognostic (3.76e-3)" "unprognostic (4.28e-2)" "unprognostic (4.90e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.78e-2)" "unprognostic (4.42e-2)" "unprognostic (1.94e-2)" "unprognostic (3.38e-2)" 14.3 7.6 3.8 9.0 4.5 8.0 7.7 4.5 5.8 3.2 11.4 3.2 3.2 7.3 1.9 2.9 2.8 6.6 6.2 4.1 4.1 2.5 3.3 7.7 12.2 4.6 5.0 5.3 1.8 2.8 2.3 6.6 5.1 2.3 3.7 1.6 2.0 2.0 2.7 6.0 3.8 15.8 4.8 9.2 2.9 4.0 4.7 5.6 3.5 8.0 7.7 6.2 2.0 6.0 0.3 3.8 3.0 2.7 9.1 10.2 1.4 19.3 21.6 8.7 8.0 0.0 1.3 6.0 5.3 8.5 14.9 13.1 10.1 29.0 20.9 14.8 6.1 5.7 2.9 0.3 7.4 26.6 1.9 4.4 5.8 18.8 10.0 5.8 35.6 9.2 3.9 7.9 7.5 0.7 3.9 26.2 3.3 0.1 7.8 26.5 1.4 2.0 1.8 3.2 2.3 10.7 7.1 0.7 16.2 4.7 0.2 41.3 29.9 15.3 7.3 5.3 14.9 2.9 2.6 3.1 4.7 19.6 2.6 0.4 6.0 0.0 3.8 5.2 3.3 0.7 6.1 5.1 8.9 0.5 4.8 4.5 0.8 2.0 6.6 0.7 11.3 3.2 3.8 4.5 4.5 5.8 4.1 4.1 4.6 5.0 5.1 4.8 4.7 6.0 73.5 3.2 3.6 31.3 7.6 45.4 3.8 5.6 3.4 2.3 1.7 2.9 6.3 2.8 2.7 0.0 0.0 0.1 24.6 0.3 0.0 1.7 36.3 0.2 1.9 47.3 1.2 4.8 73.6 2.4 1.1 8.7 2.6 0.6 0.0 58.5 28.9 0.1 13.6 1.7 99.2 0.3 2.0 29.5 36.9 21.3 0.0 27.8 26.6 185.5 21.3 0.5 13.4 22.1 85.2 12.8 1.9 0.7 20.8 2.1 0.3 0.6 2.9 1.2 0.0 2.2 24.2 3.9 2.0 1.3 44.9 0.3 27.1 3.4 0.3 2.5 LRRIQ3 "LRRC44, MGC22773" ENSG00000162620 "Leucine rich repeats and IQ motif containing 3" A6PVS8 1 74026015-74198187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 20.4" "Group enriched" "Detected in many" 5 "Early spermatids: 258.5;Late spermatids: 103.6;Spermatocytes: 204.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 7.9;JURKAT: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA030799 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA030799: AB_10601337" "unprognostic (5.94e-3)" "unprognostic (6.00e-2)" "unprognostic (6.49e-3)" "unprognostic (1.63e-1)" "unprognostic (6.62e-2)" "unprognostic (2.78e-1)" "unprognostic (2.27e-2)" "unprognostic (2.27e-1)" "unprognostic (8.17e-2)" "unprognostic (2.44e-1)" "unprognostic (1.12e-3)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (1.88e-2)" "unprognostic (4.65e-2)" 1.6 0.7 0.5 0.7 0.5 0.1 0.7 0.6 0.7 0.2 1.2 0.3 0.2 0.2 0.3 0.1 2.1 0.4 0.3 0.4 0.6 2.0 0.9 0.3 0.7 0.7 0.8 0.3 0.2 1.2 0.5 0.2 0.7 0.4 0.2 0.5 0.7 0.4 0.1 0.1 0.2 0.0 0.6 0.4 0.3 20.4 0.7 1.0 1.5 0.5 0.6 0.2 0.1 0.7 0.2 1.0 0.1 0.4 1.0 0.4 0.6 0.6 0.4 0.8 0.9 0.1 1.4 1.4 1.2 0.1 7.9 0.1 2.1 2.0 1.0 3.5 0.0 1.3 0.3 0.7 0.1 2.3 0.7 0.7 1.0 1.4 0.5 0.3 0.4 4.8 1.1 1.9 1.4 0.0 0.9 0.3 1.1 2.5 0.6 1.1 0.8 1.4 1.2 0.1 1.0 0.7 0.1 0.1 3.1 0.2 0.9 1.3 0.1 0.1 0.7 0.5 1.2 2.0 0.7 1.1 1.5 0.2 1.1 0.0 0.0 0.8 0.9 0.5 1.1 1.6 1.0 1.1 0.1 0.7 0.9 1.3 0.0 0.4 0.1 0.4 1.6 0.3 0.5 0.5 0.6 0.7 0.4 0.6 0.7 0.8 0.7 0.6 0.7 0.7 1.0 0.0 1.5 2.0 2.8 1.1 1.2 4.0 0.0 1.0 2.0 2.8 1.2 2.8 2.6 0.0 4.2 1.7 0.5 0.3 13.7 1.5 258.5 21.6 0.8 0.8 3.0 0.4 4.1 1.7 1.5 0.3 0.0 1.5 0.0 3.2 0.7 1.8 1.3 0.0 3.9 0.6 0.0 0.6 0.2 103.6 1.8 0.5 0.0 1.9 0.8 1.2 2.1 2.0 4.0 0.9 0.1 1.5 0.6 0.9 0.1 6.3 36.0 0.7 0.0 0.2 1.5 204.8 31.3 0.0 0.1 0.3 1.5 3.6 0.7 1.2 LVRN "APQ, AQPEP, FLJ90650, TAQPEP" ENSG00000172901 Laeverin Q6Q4G3 5 115962454-116027619 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 11.1;placenta: 21.8" "Group enriched" "Detected in some" 4 "Early spermatids: 29.3;Extravillous trophoblasts: 33.1;Late spermatids: 68.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 2.5" HPA053254 Enhanced "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 50: Fibroblasts - ECM organization" "HPA053254: AB_2682092" "unprognostic (1.47e-1)" "unprognostic (3.38e-3)" "unprognostic (5.81e-2)" "unprognostic (2.97e-3)" "unprognostic (5.38e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-3)" "unprognostic (1.88e-2)" "unprognostic (2.23e-1)" "unprognostic (2.23e-2)" "unprognostic (3.83e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-7)" "unprognostic (1.05e-2)" "unprognostic (5.94e-2)" "unprognostic (6.53e-2)" "unprognostic (3.31e-2)" 11.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 21.8 0.0 0.0 0.4 0.0 0.2 0.1 0.3 0.4 0.8 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 1.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 29.3 0.0 0.1 0.1 0.0 0.0 2.1 0.0 33.1 7.9 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 68.1 4.7 0.3 0.0 1.9 0.0 0.0 0.0 3.0 1.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.3 0.3 0.1 0.0 10.7 0.0 1.0 0.0 0.1 MAOA ENSG00000189221 "Monoamine oxidase A" P21397 X 43654907-43746824 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" Oxidoreductase "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 230.3" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 819.8;Proximal tubular cells: 569.9;Undifferentiated cells: 285.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 162.1;HHSteC: 302.9;HSkMC: 76.1;hTCEpi: 87.2;RT4: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009437, HPA054807, HPA059299" Enhanced Supported Mitochondria,Cytosol No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Cytosol "CAB009437: AB_2137260, HPA054807: AB_2682607, HPA059299: AB_2683970" "unprognostic (9.54e-3)" "unprognostic (1.63e-1)" "unprognostic (7.99e-2)" "unprognostic (3.07e-1)" "unprognostic (6.75e-2)" "unprognostic (3.32e-1)" "unprognostic (9.51e-2)" "unprognostic (6.89e-3)" "unprognostic (2.21e-1)" "unprognostic (4.29e-2)" "unprognostic (3.94e-1)" "unprognostic (3.54e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (4.04e-2)" "unprognostic (2.98e-3)" 143.9 27.7 24.7 8.6 27.6 0.4 71.6 26.5 26.6 26.6 13.9 116.4 163.4 24.0 14.1 46.7 39.1 16.9 49.6 22.3 31.7 76.9 119.1 63.5 2.4 26.9 32.5 40.7 39.1 31.4 4.0 30.2 56.4 46.3 117.9 28.2 77.3 35.0 33.5 37.4 230.3 24.0 21.3 6.3 55.9 3.7 41.4 9.9 118.4 34.3 5.3 65.0 38.8 19.0 0.0 3.7 0.6 9.9 162.1 0.0 0.6 0.2 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 4.6 17.2 6.1 22.3 0.1 0.0 2.5 6.9 0.5 18.6 302.9 0.0 16.9 76.1 87.2 0.2 45.2 0.1 20.0 0.0 0.3 0.4 5.7 2.9 0.1 0.8 1.6 20.7 5.0 0.0 0.3 0.5 22.3 131.8 3.1 7.8 0.0 0.0 0.3 0.4 0.5 0.0 8.7 0.0 8.2 0.7 0.0 0.3 0.0 0.0 9.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.7 27.6 26.5 26.6 22.3 31.7 26.9 32.5 56.4 21.3 41.4 19.0 35.2 70.5 146.9 23.2 4.6 11.0 177.7 32.3 116.7 5.0 13.6 10.2 101.3 94.4 49.3 60.7 22.9 11.5 0.2 248.0 121.3 36.7 25.2 50.4 42.5 43.6 38.0 4.8 4.0 13.4 21.3 24.3 40.2 175.1 5.7 7.3 53.6 193.7 6.6 3.3 5.0 137.5 67.1 12.2 2.1 33.9 5.6 6.7 10.6 21.5 17.1 25.4 0.0 7.5 1.3 49.5 140.5 0.0 2.6 64.6 819.8 569.9 32.8 27.4 6.6 4.4 30.5 1.3 0.8 120.6 14.3 207.0 3.7 3.5 285.1 129.0 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 472.1" "Cell type enhanced" "Detected in many" "Microglial cells: 337.3;Oligodendrocytes: 1134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavorable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 54.1 9.1 272.6 42.9 316.1 72.5 32.2 208.8 252.5 23.9 95.0 21.1 10.6 27.4 12.1 35.2 19.7 34.5 44.8 219.4 256.3 15.0 32.8 29.2 54.1 317.5 286.1 23.1 16.1 15.0 10.0 49.4 273.1 13.9 17.8 22.7 19.3 10.2 37.4 21.1 17.7 28.7 246.7 24.2 22.0 40.1 348.5 44.3 15.8 30.6 60.1 33.1 25.6 472.1 112.7 83.8 175.2 84.3 162.4 288.6 219.5 139.8 114.3 122.2 100.1 139.5 145.6 163.1 118.3 210.3 36.0 45.5 56.0 123.2 121.1 219.8 38.0 122.4 62.5 367.7 136.7 59.1 5.5 261.3 55.3 301.9 133.5 122.1 322.5 90.3 80.9 0.4 325.4 61.3 137.8 36.5 89.2 42.5 131.5 164.1 120.0 0.6 81.2 38.8 68.5 113.6 96.5 0.4 104.0 160.8 22.4 105.1 409.1 240.5 102.9 70.6 168.6 0.3 0.4 96.7 155.2 73.2 180.1 8.8 3.2 0.0 2.3 3.2 1.6 3.4 2.9 1.5 1.1 5.0 2.2 2.5 13.5 1.1 3.1 6.0 3.7 1.5 272.6 316.1 208.8 252.5 219.4 256.3 317.5 286.1 273.1 246.7 348.5 472.1 104.3 19.2 23.9 283.0 64.5 30.0 41.9 17.4 12.5 109.1 14.3 17.4 71.0 28.6 29.6 18.4 50.1 13.1 38.4 12.0 0.0 57.4 31.5 67.2 77.1 84.2 17.4 48.0 197.5 53.2 23.4 49.7 26.5 101.0 24.0 151.8 67.1 39.2 38.8 35.3 122.4 13.6 14.2 26.9 245.9 46.0 55.0 54.7 19.6 337.3 88.0 49.2 10.3 228.7 1134.5 128.1 12.0 17.3 18.0 72.1 5.3 6.3 22.9 10.4 52.6 65.2 73.3 29.0 82.1 24.3 24.6 7.8 38.4 17.2 14.4 40.4 MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1349.1;tongue: 1843.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1926.9;Proximal tubular cells: 1428.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434" "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favorable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" 274.6 213.6 235.9 86.7 249.7 79.1 137.9 245.9 353.6 89.6 230.2 167.7 154.7 82.0 161.3 125.3 114.5 87.2 1349.1 253.2 261.5 371.6 266.3 89.8 131.9 248.5 218.3 80.4 69.9 411.8 107.2 92.5 253.3 125.5 190.9 240.7 122.0 142.0 792.5 87.7 133.1 171.5 215.7 71.6 192.6 70.5 259.1 170.4 125.5 1843.8 165.4 131.5 62.8 237.7 268.2 219.5 257.8 173.2 369.6 280.9 282.3 215.1 295.9 300.6 304.1 252.5 215.4 355.2 112.8 264.1 358.8 214.3 303.0 355.0 425.5 207.6 253.1 337.0 173.2 376.8 202.1 384.1 223.9 277.7 241.3 271.5 152.7 236.2 235.3 308.1 183.7 217.3 395.1 157.8 300.6 317.5 158.0 376.3 266.5 235.2 349.7 310.5 460.9 251.0 249.9 153.6 182.5 257.7 384.1 205.6 191.9 341.9 149.6 220.3 211.9 187.1 252.9 264.6 264.8 407.6 266.2 312.2 184.1 271.3 186.3 200.2 202.7 267.8 218.8 258.5 236.6 224.6 241.0 258.5 230.3 221.6 28.1 214.6 253.4 184.3 320.9 321.2 235.9 249.7 245.9 353.6 253.2 261.5 248.5 218.3 253.3 215.7 259.1 237.7 44.4 60.9 54.3 54.9 78.7 81.6 109.4 562.9 50.7 165.4 81.0 86.7 1926.9 95.8 227.2 134.3 70.9 248.7 78.4 128.4 630.0 186.2 12.4 116.1 72.6 61.0 62.8 62.9 120.2 108.1 257.0 134.7 112.7 68.8 80.5 95.0 36.0 153.2 397.0 122.8 130.0 115.9 380.5 85.2 65.8 15.1 100.0 98.4 177.9 43.1 155.0 136.3 73.2 51.3 58.8 91.3 99.8 109.1 82.1 48.8 177.4 1428.3 224.5 164.1 59.2 68.3 167.8 58.0 65.6 82.7 84.0 149.5 84.3 137.4 167.8 102.6 ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210402-83431051 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Excitatory neurons: 117.1;Inhibitory neurons: 70.6;Kupffer cells: 74.4;Muller glia cells: 100.6;Oligodendrocyte precursor cells: 123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "MAIT T-cell: 16.0" "Lineage enriched" "Detected in many" 10 "T-cells: 16.0" "Cell line enhanced" "Detected in many" "CACO-2: 139.4;OE19: 158.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: AB_1078272" "unprognostic (7.21e-2)" "unprognostic (3.99e-2)" "unprognostic (2.24e-1)" "unprognostic (3.12e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (7.98e-3)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.41e-3)" "unprognostic (7.10e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.81e-7)" "unprognostic (4.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-2)" "unprognostic (4.51e-2)" 41.4 44.4 13.4 5.2 15.4 0.4 29.9 14.5 18.1 8.0 8.5 7.7 21.7 4.2 6.5 28.6 4.2 15.5 18.6 13.1 17.4 3.6 9.8 8.8 4.2 15.0 19.1 10.8 3.4 19.9 12.5 2.9 18.3 8.4 11.0 30.0 10.3 17.2 34.7 14.4 10.4 7.8 13.4 7.3 23.8 16.1 16.8 5.6 6.7 30.5 4.5 15.3 12.0 13.5 29.0 59.1 1.4 0.0 48.0 44.4 0.1 18.4 47.0 19.2 37.1 139.4 24.9 0.0 46.8 43.4 38.2 29.8 43.4 16.4 20.9 0.0 24.4 0.0 33.8 0.0 61.4 14.3 50.3 49.0 32.3 38.7 26.3 32.1 30.4 0.0 20.4 0.1 26.4 32.7 0.0 16.2 0.0 158.3 23.0 0.0 48.5 27.9 56.8 13.7 5.8 14.9 31.2 45.7 1.0 25.0 0.0 34.5 32.4 11.9 14.1 3.9 0.1 10.9 13.3 0.1 0.0 0.0 35.9 0.0 1.6 0.0 0.8 0.3 16.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 13.4 15.4 14.5 18.1 13.1 17.4 15.0 19.1 18.3 13.4 16.8 13.5 0.9 19.2 12.1 71.8 0.6 1.9 5.1 12.5 6.8 17.1 2.5 0.9 41.0 7.2 12.7 5.5 2.1 0.6 0.5 12.7 1.9 12.3 5.5 0.7 6.8 2.3 0.0 0.0 117.1 9.5 0.9 8.5 62.7 0.2 0.0 11.2 4.2 12.1 7.1 13.5 70.6 4.1 8.2 74.4 25.6 6.5 25.7 16.7 0.0 23.4 5.5 100.6 0.0 123.6 38.6 15.0 4.5 37.2 0.5 5.2 15.2 3.1 7.2 7.5 0.0 4.5 8.3 7.5 2.3 22.3 3.4 0.8 1.8 33.6 8.9 3.3 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MEST PEG1 ENSG00000106484 "Mesoderm specific transcript" Q5EB52 7 130486171-130506465 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 771.8" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 833.5;Syncytiotrophoblasts: 999.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 24.2" "Group enriched" "Detected in all" 4 "dendritic cells: 9.1;granulocytes: 19.4;T-cells: 24.2" "Cell line enriched" "Detected in many" 6 "AN3-CA: 12338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005623 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "HPA005623: AB_1079364" "unprognostic (6.14e-2)" "unprognostic (5.06e-3)" "unprognostic (9.82e-2)" "unprognostic (1.64e-3)" "unprognostic (3.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.36e-3)" "unprognostic (1.12e-1)" "unprognostic (7.81e-2)" "unprognostic (6.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (6.20e-5)" "unprognostic (7.09e-2)" "unprognostic (1.05e-1)" "unprognostic (2.30e-1)" "unprognostic (1.67e-2)" 117.5 56.2 30.7 16.1 31.3 12.6 63.1 0.0 27.5 6.1 24.1 27.4 28.7 24.4 6.6 6.8 12.0 23.4 7.5 30.2 73.5 17.8 51.8 43.4 5.5 10.2 19.3 18.8 30.0 8.0 33.2 771.8 14.0 12.7 20.9 39.2 21.4 5.5 6.9 4.6 21.6 17.8 2.5 90.2 8.8 26.3 68.4 10.3 11.8 5.2 4.8 11.0 3.9 9.8 77.9 41.7 197.1 12338.6 3.9 1.2 1.1 84.7 38.5 85.1 40.3 237.2 114.4 37.7 27.1 2.6 74.7 11.0 2.9 1.1 33.3 0.4 0.5 66.8 57.0 39.9 322.2 3.2 0.5 5.9 3.1 64.3 0.1 427.5 32.3 0.1 76.5 0.3 164.9 107.6 7.8 85.0 124.1 113.3 20.0 0.8 2168.8 24.5 92.0 72.0 693.2 2.0 71.9 234.0 1.0 195.6 9.2 57.3 33.6 29.2 0.7 276.1 5.6 3.4 8.6 0.7 103.3 1.2 9.7 19.4 2.6 9.1 0.9 2.9 2.2 3.9 2.5 1.8 9.1 3.4 9.4 24.2 1.5 4.3 1.7 0.4 0.1 6.7 30.7 31.3 0.0 27.5 30.2 73.5 10.2 19.3 14.0 2.5 68.4 9.8 7.4 6.4 6.2 12.7 3.3 4.5 47.3 8.6 9.1 13.5 33.3 36.1 0.9 20.0 5.7 16.5 4.2 833.5 2.1 9.3 11.7 20.3 62.7 8.2 12.7 6.0 29.5 35.9 40.8 40.0 187.8 200.3 3.1 9.5 0.0 6.3 44.6 20.4 92.7 1.7 28.1 19.4 6.1 8.8 3.2 37.5 84.8 6.6 1.8 11.2 1.3 45.3 0.0 18.1 1.8 22.8 27.5 13.5 2.3 27.1 24.6 12.3 2.9 22.0 19.7 205.6 12.0 35.7 36.7 10.0 0.6 999.6 2.1 124.8 31.5 23.4 MGAT3 GNT-III ENSG00000128268 "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase" Q09327 22 39457012-39492194 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.0;intestine: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Bipolar cells: 30.7;Excitatory neurons: 25.1;Inhibitory neurons: 27.4;Oligodendrocytes: 45.7;Proximal enterocytes: 37.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4;eosinophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 65.1;HMC-1: 56.0;OE19: 58.8;U-266/70: 73.6;U-266/84: 32.6;U-698: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved "Intracellular and membrane" NA NA 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA017598: AB_1853853" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (5.71e-3)" "unprognostic (8.92e-2)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (6.77e-2)" "unprognostic (8.12e-3)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.04e-8)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (5.89e-2)" "unprognostic (4.92e-2)" 7.8 1.1 26.8 4.0 20.9 10.8 6.4 7.6 47.0 6.2 0.0 5.2 21.5 3.8 0.8 1.1 3.4 3.8 4.8 30.3 10.0 3.0 0.2 14.9 7.6 28.1 15.6 1.2 3.1 0.4 1.8 10.5 21.8 1.2 4.6 6.7 1.8 1.0 1.5 2.3 28.4 2.8 4.8 4.8 7.4 5.4 23.9 1.8 1.5 1.8 9.0 1.6 1.5 27.3 0.3 0.4 10.4 1.0 0.0 0.0 65.1 0.5 0.7 0.5 0.0 14.9 3.7 23.4 8.1 0.0 0.2 1.3 5.4 0.0 0.1 0.0 0.5 18.9 0.0 0.2 0.2 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 15.8 2.9 0.0 0.2 0.6 1.4 3.1 58.8 0.0 1.2 0.0 3.9 0.4 0.6 6.0 4.4 0.0 0.0 0.0 18.5 0.8 1.0 0.0 0.1 8.1 0.1 0.1 73.6 32.6 32.6 0.2 0.1 1.7 1.4 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.8 20.9 7.6 47.0 30.3 10.0 28.1 15.6 21.8 4.8 23.9 27.3 2.0 44.8 3.0 6.5 2.2 0.4 0.1 1.8 0.0 30.7 0.6 1.1 1.9 1.5 3.7 0.0 6.2 5.5 0.0 4.1 0.0 0.0 19.1 0.9 11.0 2.5 7.8 13.7 25.1 0.2 12.0 2.3 10.2 2.0 2.5 0.0 0.0 0.0 1.5 13.5 27.4 3.8 2.0 0.0 2.3 16.6 4.4 0.9 0.0 0.0 0.1 1.5 0.0 21.6 45.7 1.8 6.1 3.8 1.7 0.3 37.4 1.8 5.2 2.3 6.6 0.3 4.3 0.7 1.2 0.2 0.6 3.7 0.5 0.6 4.5 1.5 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1205.9;Club cells: 1308.7;Hepatocytes: 4345.6;Proximal tubular cells: 1265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Cell line enhanced" "Detected in many" "ASC diff: 5391.4;ASC TERT1: 2078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" 1096.9 1137.3 139.2 76.1 143.9 79.3 574.8 131.4 200.7 69.7 111.9 315.5 128.9 32.7 43.9 195.3 78.4 200.8 135.1 133.9 165.4 392.9 3104.7 177.2 3.5 156.5 155.7 11.4 131.3 0.8 52.6 14.2 166.6 161.2 212.8 7.0 155.3 55.8 25.5 88.8 119.5 44.7 146.4 7.3 131.4 20.2 147.5 14.0 272.3 43.3 7.7 267.9 114.7 132.9 1.4 495.2 115.6 139.4 5391.4 2078.4 1.5 408.5 418.5 220.6 339.1 186.0 838.6 0.4 48.5 535.8 694.2 2.4 317.0 663.5 202.9 1.1 41.4 175.7 256.6 664.8 1252.0 350.4 1.2 1375.9 714.7 671.2 710.5 540.4 393.1 0.1 126.7 0.6 486.3 101.2 0.3 137.0 987.6 0.7 391.2 0.4 69.3 229.3 503.3 982.1 21.8 17.1 645.8 411.8 17.5 630.1 442.5 190.8 248.0 226.1 30.5 447.3 541.1 0.6 1.7 1.5 748.1 538.5 7.1 11.3 170.2 1.8 0.1 26.3 0.5 1.0 0.2 0.1 123.5 0.0 0.1 0.1 5.9 0.2 5.9 34.1 1.1 55.9 139.2 143.9 131.4 200.7 133.9 165.4 156.5 155.7 166.6 146.4 147.5 132.9 39.6 266.0 651.3 130.2 14.0 25.6 130.2 1205.9 91.0 0.0 383.8 262.6 5.1 574.7 1308.7 71.7 0.0 2.9 9.8 288.1 181.9 26.9 25.4 299.9 198.2 19.6 45.6 92.8 4.4 434.1 218.1 404.5 153.9 947.9 34.1 26.3 67.5 4345.6 160.2 0.0 0.5 280.5 740.6 176.4 52.0 17.9 33.2 75.7 39.2 6.5 224.4 1.0 5.2 1.0 0.8 322.7 175.0 113.2 6.0 467.2 209.5 1265.6 526.1 1.3 0.0 11.3 124.3 0.7 2.3 510.3 17.6 7.9 22.1 152.4 534.1 883.3 MLEC KIAA0152 ENSG00000110917 Malectin Q14165 12 120687149-120701859 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Undifferentiated cells: 397.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 880000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.60e-6)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (5.41e-2)" "unprognostic (3.94e-1)" "unprognostic (3.39e-1)" "unprognostic (9.77e-2)" "unprognostic (5.90e-2)" "unprognostic (1.76e-1)" "unprognostic (1.15e-2)" "prognostic favorable (8.77e-4)" "unprognostic (1.98e-1)" "unprognostic (7.88e-2)" "unprognostic (1.05e-1)" 51.7 93.1 35.4 51.8 36.7 34.6 44.3 33.0 34.5 52.8 40.3 127.0 78.3 37.2 138.1 24.5 48.5 48.5 65.9 34.7 40.0 73.5 78.2 34.9 30.3 42.3 39.4 49.2 62.7 101.2 36.7 45.7 37.8 62.4 117.3 25.3 50.7 64.9 79.8 27.8 86.0 50.0 40.0 30.1 45.3 69.1 42.9 33.3 101.0 82.9 37.3 34.1 17.4 37.6 122.7 177.9 113.6 151.8 196.3 107.4 127.9 144.5 126.3 108.9 80.1 127.5 75.1 100.3 129.0 142.2 85.4 101.9 140.4 87.4 138.7 86.5 76.9 142.4 79.4 100.6 72.1 199.3 123.1 82.2 82.7 116.0 91.4 174.1 97.2 93.9 85.9 112.2 116.3 127.8 106.4 122.2 158.1 156.6 91.7 115.7 82.0 109.1 132.2 204.0 58.2 69.2 166.5 85.9 86.0 143.0 127.0 144.6 79.2 115.8 108.5 112.8 100.3 83.3 165.0 76.8 147.6 147.9 120.1 0.5 6.0 8.0 3.8 7.5 4.1 4.7 2.3 3.4 5.0 6.9 4.0 3.4 1.6 3.9 6.5 18.6 2.4 2.2 35.4 36.7 33.0 34.5 34.7 40.0 42.3 39.4 37.8 40.0 42.9 37.6 151.4 25.6 62.2 23.2 65.7 72.8 70.6 32.0 55.2 40.9 99.7 76.3 145.3 97.2 40.0 86.5 45.9 88.4 105.7 155.3 37.2 134.2 243.3 78.3 127.6 94.1 80.3 68.5 21.4 183.7 176.9 90.5 69.3 80.2 49.5 99.8 27.1 206.1 126.8 84.1 24.7 199.2 30.5 61.7 73.2 228.0 82.6 70.1 193.9 34.7 56.4 81.8 74.2 32.2 23.0 95.8 86.0 108.0 217.4 152.6 135.4 121.7 41.9 45.3 85.5 61.4 78.5 165.6 153.4 52.8 58.7 115.6 51.2 142.5 397.0 82.2 MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 609.7" "Group enriched" "Detected in many" 4 "Cholangiocytes: 84.4;Enteroendocrine cells: 90.1;Hepatocytes: 286.6;Proximal enterocytes: 108.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 46.5;K-562: 15.2;SCLC-21H: 25.5;T-47d: 11.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" 72.3 85.1 5.5 0.7 4.1 0.2 51.2 16.3 9.4 3.0 0.2 7.8 58.8 0.6 16.3 3.4 12.9 5.5 3.5 4.5 1.4 36.2 609.7 2.7 0.0 5.6 1.4 4.9 23.1 6.3 13.4 0.0 6.1 3.7 1.5 0.7 8.7 0.8 58.1 4.5 46.8 0.5 1.3 0.3 4.7 30.9 2.2 0.9 7.3 13.8 0.0 2.0 2.7 2.1 0.2 2.5 0.0 5.9 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 7.5 0.0 0.3 0.0 0.6 1.2 0.0 0.0 0.0 0.2 6.1 0.0 4.8 46.5 1.3 0.2 1.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.1 6.3 0.1 0.0 0.7 8.2 1.0 0.0 0.0 1.2 0.0 0.1 25.5 0.7 1.0 4.4 0.0 0.1 11.4 6.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 4.1 16.3 9.4 4.5 1.4 5.6 1.4 6.1 1.3 2.2 2.1 0.6 0.0 16.2 2.3 1.6 1.1 4.8 0.6 0.6 9.9 1.4 1.3 3.4 84.4 4.7 3.7 20.9 0.1 0.3 3.2 1.9 2.9 3.2 0.7 0.2 2.5 90.1 16.0 33.4 1.0 0.1 6.5 4.6 0.8 0.0 0.1 12.8 286.6 0.4 1.7 29.1 19.6 0.0 11.2 1.5 1.2 2.8 2.8 7.2 30.9 0.2 2.0 1.0 2.0 0.9 1.4 13.9 1.2 0.1 2.2 108.9 14.1 3.2 6.5 0.0 23.9 1.0 5.1 1.1 0.5 0.9 0.5 1.7 0.0 31.9 4.0 MMD "MMA, PAQR11" ENSG00000108960 "Monocyte to macrophage differentiation associated" Q15546 17 55392622-55421924 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 152.2;brain: 87.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 56.4;Macrophages: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 110.0;HSkMC: 199.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026978 Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA026978: AB_2672068" "unprognostic (1.33e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.52e-5)" "prognostic unfavorable (3.88e-4)" "unprognostic (2.48e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (6.39e-5)" "unprognostic (8.07e-3)" "unprognostic (6.67e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (3.71e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.12e-2)" 152.2 13.3 54.2 15.7 55.9 14.1 28.4 11.6 58.5 4.8 5.4 13.4 10.9 6.2 9.7 7.2 4.2 9.4 6.5 87.5 19.7 8.5 13.2 10.0 17.8 16.3 29.2 2.8 3.5 3.7 4.8 21.4 16.1 6.2 12.9 12.8 4.9 7.9 3.4 5.3 10.1 11.4 24.2 16.5 5.4 17.0 21.6 8.2 6.6 8.0 12.1 11.6 4.0 27.2 20.1 46.3 67.0 13.5 110.0 86.0 39.2 13.6 5.2 7.2 10.2 7.4 53.8 30.1 39.6 4.5 20.1 1.5 18.8 14.3 14.9 41.5 9.5 11.0 2.5 85.2 29.8 10.8 3.2 199.4 4.5 10.1 11.4 15.7 9.0 27.4 4.4 20.5 15.1 2.8 29.7 8.2 20.6 3.3 15.6 12.4 46.9 10.0 19.7 5.0 7.0 72.8 5.0 7.1 10.9 41.5 15.4 17.3 9.6 18.7 26.6 15.5 14.0 13.1 6.2 45.7 26.7 8.5 15.2 14.2 1.5 1.9 1.7 2.1 4.9 4.5 1.8 3.3 4.3 5.0 3.1 3.3 4.6 2.9 1.9 1.3 2.1 17.5 54.2 55.9 11.6 58.5 87.5 19.7 16.3 29.2 16.1 24.2 21.6 27.2 15.5 3.2 0.6 5.2 20.3 5.4 23.7 9.3 5.2 28.2 3.3 3.3 4.6 11.5 2.7 7.3 4.2 11.5 12.2 3.4 15.6 27.7 2.5 4.8 8.9 16.4 7.8 27.3 36.5 1.3 18.8 12.7 2.6 8.7 0.0 3.5 19.6 17.9 37.6 16.8 11.5 6.8 8.2 56.4 35.9 4.0 1.8 85.9 7.2 14.0 48.6 14.5 12.3 7.5 7.2 17.3 1.6 3.4 12.1 26.2 2.3 9.8 2.4 10.2 19.7 5.2 11.4 28.9 23.3 3.1 17.5 20.0 17.7 1.3 8.6 6.1 MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.8;Distal enterocytes: 109.3;Proximal enterocytes: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 93.6;Hep G2: 51.1;OE19: 44.6;SK-BR-3: 47.3;WM-115: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" 11.9 3.8 8.9 4.4 6.0 0.4 7.6 7.3 11.2 5.7 5.8 28.0 40.2 3.5 1.1 4.6 6.1 14.3 41.2 6.9 8.7 14.9 50.1 9.9 2.1 15.8 10.6 1.1 18.5 12.7 8.8 28.4 16.8 4.4 14.3 1.5 8.4 9.5 7.0 4.3 33.0 3.7 5.8 9.3 29.6 34.9 18.7 1.0 46.7 5.6 1.3 5.1 2.8 8.6 15.3 11.4 5.8 30.4 6.0 0.3 93.6 1.4 0.8 5.4 1.2 9.1 38.3 0.2 17.7 1.6 4.2 21.0 5.1 4.4 1.6 0.1 10.0 0.1 4.9 51.1 7.7 0.3 19.5 3.1 7.8 0.9 2.3 8.4 3.7 8.5 12.9 0.1 1.8 7.6 0.7 2.6 17.2 44.6 3.2 7.6 0.7 8.3 16.6 5.4 1.6 10.4 20.0 47.3 9.5 13.2 5.2 8.2 3.4 0.4 9.1 3.5 1.3 0.2 0.1 0.3 1.9 2.3 78.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.9 6.0 7.3 11.2 6.9 8.7 15.8 10.6 16.8 5.8 18.7 8.6 14.3 19.2 14.4 9.1 0.7 2.5 1.0 4.9 2.8 3.4 5.0 3.0 24.7 55.8 12.6 18.4 16.7 48.2 1.6 109.3 1.9 35.7 5.0 3.6 1.1 17.2 11.4 2.7 1.4 12.0 49.2 4.5 35.2 6.4 0.0 18.6 13.6 39.2 12.9 1.7 1.2 33.3 10.2 3.0 0.3 6.9 0.9 0.9 1.8 1.0 0.0 2.1 0.0 4.5 1.4 13.3 38.5 3.4 0.3 1.3 67.3 7.3 6.0 1.9 0.0 0.7 2.4 0.9 4.6 3.3 2.3 48.4 0.7 23.2 45.0 1.7 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671658-222709930 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "gallbladder: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Breast glandular cells: 7.2;Cholangiocytes: 7.2;Endometrial ciliated cells: 3.9;Exocrine glandular cells: 5.1;Glandular and luminal cells: 4.9;Hepatocytes: 3.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049944, HPA076308" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "Endoplasmic reticulum" "HPA049944: AB_2680964, HPA076308: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" 0.9 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.0 16.8 0.4 0.1 0.1 0.8 3.1 0.4 0.0 0.1 0.6 0.0 0.2 0.6 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.1 0.4 0.6 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.3 0.7 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.9 3.9 0.6 0.1 0.0 0.0 2.5 5.1 0.0 0.1 0.0 4.9 0.0 0.2 0.0 3.2 0.9 0.0 1.9 0.0 0.0 0.3 0.3 0.1 0.0 1.3 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.9 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 MRAP "B27, C21orf61, FALP" ENSG00000170262 "Melanocortin 2 receptor accessory protein" Q8TCY5 21 32291813-32314784 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "adipose tissue: 75.6;adrenal gland: 166.5;breast: 44.2" "Group enriched" "Detected in some" 5 "Early spermatids: 16.1;Granulosa cells: 43.7;Horizontal cells: 43.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 1.5;HSkMC: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011024, HPA011093" Uncertain Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA011024: AB_10599292, HPA011093: AB_10600889" "unprognostic (1.38e-1)" "unprognostic (1.55e-3)" "unprognostic (1.53e-1)" "unprognostic (1.11e-1)" "unprognostic (9.53e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.80e-2)" "unprognostic (4.12e-1)" "unprognostic (6.30e-6)" "unprognostic (3.32e-2)" "unprognostic (2.37e-1)" "unprognostic (1.18e-1)" "unprognostic (5.76e-2)" 75.6 166.5 0.1 1.8 0.1 0.0 44.2 0.0 0.5 0.1 0.8 1.2 0.2 0.0 0.0 0.1 0.0 0.6 2.0 0.1 0.0 0.3 2.4 1.0 0.1 0.2 0.0 2.0 0.7 0.0 0.1 1.7 0.1 0.0 0.2 1.0 2.0 0.0 0.2 1.3 3.5 0.1 0.0 0.0 0.6 0.5 0.0 0.1 0.7 0.2 0.0 1.4 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.7 0.2 0.4 0.2 0.8 0.2 0.5 0.0 1.9 0.1 0.5 0.7 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.4 0.0 0.1 0.0 0.0 0.7 0.0 0.1 1.3 0.0 0.0 0.0 43.7 0.0 1.7 0.1 43.7 0.6 0.0 0.0 0.0 0.0 6.6 0.6 0.1 0.0 0.0 0.0 0.3 0.0 2.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.6 1.6 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 MRAS "M-RAs, R-RAS3, RRAS3" ENSG00000158186 "Muscle RAS oncogene homolog" O14807 3 138347648-138405534 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 202.3;heart muscle: 132.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 121.7;Distal tubular cells: 58.7;Theca cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 9 "monocytes: 25.0" "Cell line enhanced" "Detected in many" "BJ: 92.9;EFO-21: 113.7;fHDF/TERT166: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042728 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Vesicles "HPA042728: AB_10796582" "unprognostic (1.96e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.69e-1)" "unprognostic (5.32e-2)" "unprognostic (8.96e-2)" "unprognostic (3.85e-3)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (3.18e-3)" "unprognostic (1.78e-2)" "unprognostic (6.25e-2)" "unprognostic (2.21e-1)" "unprognostic (4.23e-2)" 91.9 67.7 112.7 10.8 130.6 1.7 46.7 118.2 105.5 17.3 48.9 24.2 3.3 28.7 7.1 7.9 26.4 12.0 132.9 105.6 132.8 22.9 5.5 18.4 5.2 126.1 135.9 48.6 5.7 8.2 17.7 10.6 112.9 15.3 4.1 15.9 13.4 15.0 80.4 12.2 8.7 23.2 110.3 12.2 12.0 9.6 202.3 4.9 26.4 48.0 3.3 29.1 12.1 97.8 0.8 7.9 15.8 24.5 59.6 29.2 40.0 92.9 16.0 7.3 8.2 3.3 3.1 0.3 113.7 70.4 18.6 0.1 9.0 1.8 6.1 7.7 3.1 0.5 4.8 20.1 15.9 0.0 1.9 41.5 5.9 0.7 1.4 13.6 1.3 0.0 10.7 0.8 31.4 3.7 0.0 20.4 19.1 0.0 2.7 1.1 33.8 0.2 30.4 2.0 18.6 42.0 62.8 0.7 45.9 10.9 16.1 37.7 0.6 23.7 25.3 24.3 2.4 0.1 1.0 1.2 21.4 0.1 11.4 0.2 2.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.3 0.8 25.0 0.1 0.0 0.8 112.7 130.6 118.2 105.5 105.6 132.8 126.1 135.9 112.9 110.3 202.3 97.8 8.9 9.6 1.5 54.2 0.8 2.2 3.0 3.4 1.2 5.6 28.8 34.8 121.7 2.8 3.5 9.2 10.4 20.1 0.2 0.0 58.7 8.6 11.6 1.0 21.4 14.5 1.8 0.0 25.5 3.2 3.2 23.0 2.0 1.5 6.3 35.2 12.8 1.6 26.3 28.6 20.6 0.0 2.0 15.1 18.4 40.0 23.3 18.2 28.4 20.6 12.2 24.3 0.0 28.6 11.0 3.8 0.0 34.3 0.1 3.3 0.0 27.5 1.3 9.6 6.6 20.8 18.9 7.3 18.6 0.4 1.0 14.4 0.8 59.1 0.0 0.6 MS4A7 "CD20L4, CFFM4, MS4A8" ENSG00000166927 "Membrane spanning 4-domains A7" Q9GZW8 11 60378485-60395951 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 311.4;Kupffer cells: 1060.3;Macrophages: 567.5;monocytes: 184.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "intermediate monocyte: 747.4;non-classical monocyte: 1486.0" "Lineage enriched" "Detected in many" 12 "monocytes: 1486.0" "Cell line enriched" "Detected in some" 25 "THP-1: 114.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA017418, CAB026387" Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB026387: , HPA017418: AB_1854137" "unprognostic (1.43e-1)" "unprognostic (2.60e-3)" "unprognostic (3.24e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (3.02e-2)" "unprognostic (4.85e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" "unprognostic (4.59e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" 46.9 37.6 6.3 50.9 5.0 10.7 30.7 4.5 13.7 18.2 13.9 21.4 17.6 7.6 4.1 12.7 6.6 46.8 9.9 4.2 8.7 8.0 66.5 75.7 23.2 12.8 10.4 6.0 6.0 9.0 4.7 43.9 11.4 4.9 23.3 1.2 6.7 9.0 1.9 2.3 25.1 15.9 7.4 196.6 14.8 4.7 17.1 18.2 7.3 4.1 18.6 41.2 3.9 18.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.5 0.1 0.0 0.1 1.1 0.1 0.1 0.0 2.8 0.0 0.1 0.1 0.8 0.5 0.0 0.0 114.2 0.0 0.1 0.1 0.1 0.1 0.2 0.2 3.0 0.0 3.1 0.0 8.3 188.0 2.5 0.8 747.4 1.1 22.3 0.6 0.5 120.9 19.7 0.8 0.4 9.3 0.8 1486.0 3.2 0.9 137.8 6.3 5.0 4.5 13.7 4.2 8.7 12.8 10.4 11.4 7.4 17.1 18.3 5.0 12.8 31.4 0.0 30.6 2.7 0.8 0.0 0.6 3.6 14.7 9.9 2.1 0.0 3.7 9.2 0.0 1.0 1.4 0.3 0.0 0.0 2.4 0.1 0.0 12.2 0.0 10.1 0.1 0.2 1.7 3.9 1.5 0.1 13.9 0.1 11.0 4.7 311.4 0.0 0.2 0.0 0.0 1060.3 93.4 1.2 1.2 567.5 1.8 59.0 184.8 0.4 4.1 0.0 0.3 0.1 1.1 0.0 1.8 1.1 0.0 0.7 7.3 0.5 19.7 2.2 1.2 0.0 0.4 0.9 1.8 1.9 5.3 0.3 0.1 1.0 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 222644.8;heart muscle: 255389.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107039.5;Hepatocytes: 59794.3;Proximal enterocytes: 98329.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 54167.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB016241: AB_2229888, HPA069328: AB_2686122" "unprognostic (4.39e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "prognostic favorable (2.29e-4)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (1.20e-2)" "unprognostic (6.60e-2)" "unprognostic (2.83e-2)" "unprognostic (5.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-2)" 22006.8 46968.9 171347.0 8727.7 151652.8 11321.8 17952.5 132201.9 222644.8 10440.9 179120.2 42606.0 27505.7 11582.9 14226.0 20791.8 10700.5 11452.7 255389.3 151507.6 137459.2 63061.8 96575.5 12744.7 9111.4 176794.8 152802.2 8124.5 19467.4 41236.2 7420.2 10527.8 168465.9 12427.0 28389.7 12503.0 23260.1 17753.2 147209.5 26849.0 35366.3 13146.2 138626.1 16284.7 44852.9 10932.5 176888.2 7461.1 14056.3 184587.7 8381.2 17415.3 10559.7 131378.4 5837.6 8554.3 11384.1 12431.0 25510.2 11563.1 12037.2 12867.2 4284.9 3189.4 5257.4 10383.6 18320.5 15138.9 6040.7 9857.6 3118.2 21430.9 1326.6 11407.4 4515.1 7226.0 8040.6 9130.6 54167.9 19725.4 3521.2 5336.1 11055.5 13603.9 11589.8 3149.9 6917.5 14668.4 3902.1 8485.5 5916.3 10551.1 9525.6 14037.0 4378.4 23591.9 2905.0 7814.2 6900.5 5664.0 3401.6 9177.9 15910.6 15016.1 5414.7 7189.1 4466.7 17018.9 8305.7 13626.1 9809.7 17703.3 15637.8 12617.8 8438.9 12565.9 6642.1 4951.2 5072.9 3542.6 6235.7 13711.8 6294.4 5305.8 9759.2 3824.6 3085.1 4907.9 3420.5 5374.6 3047.3 3425.6 3444.6 5567.3 3080.8 3911.2 1900.4 3759.1 5775.1 4847.5 2947.7 3929.0 171347.0 151652.8 132201.9 222644.8 151507.6 137459.2 176794.8 152802.2 168465.9 138626.1 176888.2 131378.4 3924.0 2900.6 3897.1 0.0 13282.9 9769.7 9713.9 22625.0 20857.7 0.0 12033.2 11841.6 107039.5 30777.5 16135.4 19596.3 0.0 0.0 9288.4 40726.1 4255.4 7191.4 1555.3 13044.7 9033.9 7847.9 7514.7 45610.3 0.0 5089.4 0.0 6305.3 19235.7 25645.6 3832.6 20400.0 25951.4 59794.3 0.0 0.0 0.0 24302.1 19071.0 45533.4 7744.0 7398.4 11696.4 12124.7 6894.2 0.0 15180.0 0.0 8901.3 0.0 0.0 6410.5 23865.9 8490.1 13829.3 9441.3 98329.8 33652.6 10474.0 0.0 13614.6 11019.8 9403.5 12096.5 14338.7 27110.9 11475.1 0.0 11502.4 15179.6 27138.6 21770.7 MT-ND5 "MTND5, NAD5, ND5" ENSG00000198786 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5" P03915 MT 12337-14148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 25147.7;heart muscle: 26116.9;skeletal muscle: 25697.4" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 35040.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 10198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.87e-1)" "unprognostic (3.18e-2)" "unprognostic (3.00e-1)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-3)" "unprognostic (5.09e-3)" "unprognostic (1.06e-2)" "unprognostic (3.01e-1)" "unprognostic (3.29e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.31e-5)" "unprognostic (9.93e-3)" "unprognostic (8.75e-2)" "unprognostic (1.26e-2)" "unprognostic (3.68e-2)" 5288.6 4777.7 18907.8 1742.2 18307.4 1525.5 2456.7 14400.2 21432.3 1614.3 22368.1 4280.6 4135.2 1972.7 2508.1 2717.8 3030.2 2040.5 26116.9 16370.1 20521.2 8014.5 10041.3 2683.6 1180.6 25147.7 20794.2 1886.3 2631.6 4813.1 1528.8 1691.5 23065.0 2812.7 2879.0 3264.8 2819.2 2163.8 25697.4 6657.3 4780.7 2643.7 13881.7 2014.4 6673.9 1678.5 21024.6 794.7 2059.1 19444.2 1541.4 3557.5 1537.7 13870.1 1615.8 1671.5 1998.7 1937.9 5903.9 1530.3 1075.8 3208.3 492.5 355.1 583.1 2472.6 2051.0 3865.3 1590.5 1510.4 397.3 3350.6 191.2 1685.7 583.4 2182.3 1281.4 2840.4 10198.2 4239.2 678.8 2010.7 2824.3 2305.4 1315.5 401.6 951.8 1933.5 725.2 1233.3 1056.8 1794.8 1216.3 3046.1 757.3 2453.4 397.5 910.2 903.0 1432.9 938.2 1668.7 2083.2 3132.2 595.0 904.1 1496.1 2636.3 894.4 3001.9 1927.1 2979.2 5094.9 2013.2 1403.2 2409.7 1271.9 678.8 1246.0 1066.9 1077.4 1780.4 897.7 2851.8 1521.7 874.2 771.4 980.3 922.8 979.1 753.9 839.2 746.5 1096.6 729.2 869.0 446.2 785.1 1039.5 890.3 628.6 492.0 18907.8 18307.4 14400.2 21432.3 16370.1 20521.2 25147.7 20794.2 23065.0 13881.7 21024.6 13870.1 773.3 628.2 594.2 0.0 1707.9 895.1 1050.1 1005.5 3261.6 0.0 1003.4 1025.1 35040.8 2566.4 934.5 1156.8 0.0 0.0 977.0 3181.2 283.7 804.1 109.5 3130.4 2025.6 1614.3 782.9 3776.6 0.0 936.6 0.0 1437.2 3609.6 5212.8 862.1 2987.5 2623.3 6597.7 0.0 0.0 0.0 1776.8 583.9 3664.2 661.9 528.9 1057.5 1364.5 608.3 0.0 1303.9 0.0 756.0 0.0 0.0 1327.8 2211.7 848.6 2674.2 753.3 4484.5 2410.8 1282.0 0.0 696.8 1941.5 1558.6 652.2 521.9 3002.4 973.6 0.0 1527.8 1560.9 1650.5 1506.6 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" 14 64388031-64463457 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 142.9;Proximal tubular cells: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 56.4 18.0 8.6 20.0 17.4 27.0 29.8 8.3 12.3 16.9 15.0 23.3 19.7 16.1 9.9 25.1 16.0 13.1 28.1 12.9 8.1 55.3 356.9 15.4 23.6 7.5 7.8 24.9 23.8 27.5 9.2 13.3 7.0 12.9 27.5 3.6 15.6 13.8 64.1 17.1 18.9 20.0 7.2 14.5 17.9 4.7 8.9 30.2 20.5 61.9 27.7 18.6 16.6 8.3 294.1 164.9 58.5 143.6 70.5 53.4 95.7 106.4 83.3 148.1 147.4 161.2 144.2 103.3 49.6 67.1 68.3 146.0 177.6 111.2 160.4 107.3 117.9 122.2 143.5 131.8 50.6 104.5 81.2 43.0 37.3 124.3 66.4 57.5 93.1 98.1 108.5 98.7 114.7 270.1 179.9 62.3 118.0 186.5 160.4 138.3 201.2 114.4 110.5 160.9 128.7 49.0 183.7 111.4 58.3 54.0 164.4 58.6 51.5 115.1 184.1 102.2 134.2 58.8 65.6 177.9 107.4 125.2 134.8 0.4 11.7 0.1 9.7 19.5 13.0 27.0 10.1 12.3 17.7 15.3 7.8 10.7 0.9 17.8 16.7 4.0 19.5 12.2 8.6 17.4 8.3 12.3 12.9 8.1 7.5 7.8 7.0 7.2 8.9 8.3 8.1 19.2 23.5 15.0 16.2 13.8 14.2 14.7 13.6 0.0 9.8 8.1 43.9 15.7 19.5 16.5 0.0 30.6 10.8 7.9 41.1 16.9 1.4 6.8 11.7 12.3 3.0 42.3 19.5 10.3 30.9 14.9 15.3 8.7 50.7 27.2 12.8 142.9 25.3 0.0 15.6 14.3 2.0 13.0 11.0 1.5 13.1 12.3 14.2 8.4 13.3 0.0 8.2 14.1 10.9 11.7 6.3 13.2 24.1 10.2 8.2 75.3 11.5 0.0 19.7 13.1 19.3 0.9 8.9 19.5 10.7 9.9 16.6 21.4 24.6 12.7 MXD4 "bHLHc12, MAD4, MST149, MSTP149" ENSG00000123933 "MAX dimerization protein 4" Q14582 4 2247432-2262109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 169.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053363 Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA053363: AB_2682128" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (2.84e-2)" "unprognostic (3.54e-2)" "prognostic favorable (2.21e-5)" "unprognostic (1.64e-1)" "unprognostic (5.94e-2)" "unprognostic (8.37e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.39e-5)" "unprognostic (5.65e-2)" "unprognostic (1.09e-3)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.12e-2)" 38.6 42.0 43.9 11.3 39.8 29.8 35.9 62.1 58.4 31.1 38.2 35.2 18.3 37.1 11.6 21.0 27.9 15.1 36.2 40.9 37.7 38.8 20.6 38.5 20.2 40.6 40.5 23.2 25.3 12.4 63.5 14.3 39.7 33.0 7.2 5.9 35.0 25.0 24.1 25.9 28.6 14.0 37.5 57.6 31.2 22.1 41.2 23.2 33.4 14.4 9.1 25.1 19.4 39.6 2.3 8.3 12.9 15.5 44.2 32.6 3.0 16.4 16.6 12.0 12.2 2.0 7.1 7.1 36.1 25.0 6.4 11.2 3.7 13.0 3.1 6.3 39.5 1.3 29.0 23.6 32.4 5.5 14.5 51.1 22.9 3.9 6.1 26.5 28.9 10.3 9.8 11.6 11.3 16.2 12.6 31.6 5.1 9.6 36.4 8.5 4.4 15.1 14.2 13.0 20.8 38.7 15.4 7.5 12.3 15.7 35.2 34.4 68.7 13.3 5.3 9.9 3.7 17.6 13.2 2.8 18.2 4.9 4.0 7.2 2.7 3.4 3.3 3.0 2.7 2.2 3.0 3.3 2.5 2.0 1.5 1.5 1.1 2.0 3.0 7.2 4.0 1.4 43.9 39.8 62.1 58.4 40.9 37.7 40.6 40.5 39.7 37.5 41.2 39.6 169.7 19.2 19.9 48.0 37.9 19.1 15.3 13.6 7.4 81.6 67.8 67.1 18.4 17.2 16.1 60.7 87.6 44.3 129.6 47.9 15.6 16.5 10.1 39.6 81.9 54.7 33.6 20.6 11.6 18.3 48.4 53.6 23.0 42.8 24.1 37.9 103.5 35.5 50.3 65.6 20.5 55.9 10.2 72.9 27.5 28.8 33.2 58.8 23.2 27.2 21.6 67.9 68.0 19.1 19.7 17.5 31.8 56.4 54.0 28.7 44.0 22.1 13.4 97.1 26.3 39.6 48.5 7.0 37.0 17.3 26.3 32.7 54.7 100.5 38.2 13.1 MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adipose tissue: 7.7;breast: 6.9;pancreas: 5.6;stomach 1: 2.3" "Group enriched" "Detected in some" 4 "Adipocytes: 5.5;Distal tubular cells: 3.9;Exocrine glandular cells: 2.2;Extravillous trophoblasts: 1.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 106 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 106 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 31 "RH-30: 134.6" "Not detected" "Not detected" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (6.86e-2)" "unprognostic (6.51e-3)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-2)" "unprognostic (2.10e-3)" "unprognostic (4.32e-1)" "unprognostic (1.77e-1)" "unprognostic (8.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.01e-4)" "unprognostic (1.63e-2)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.67e-1)" 7.7 0.1 0.0 0.2 0.0 0.0 6.9 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.5 1.0 0.0 0.0 0.7 0.1 0.4 0.6 0.1 0.0 0.1 5.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.0 0.4 0.9 0.5 0.1 0.0 0.8 2.3 0.4 0.0 0.8 0.4 0.2 0.3 0.5 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 134.6 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.2 1.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MYO16 "KIAA0865, Myo16b, MYR8, NYAP3, PPP1R107" ENSG00000041515 "Myosin XVI" Q9Y6X6 13 108596152-109208005 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4" "Group enriched" "Detected in some" 8 "Inhibitory neurons: 460.0;Oligodendrocyte precursor cells: 299.6" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;SH-SY5Y: 4.5;U-2197: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 72.6" "Low region specificity" "Detected in all" "HPA040110, HPA058769, HPA071948" Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA040110: AB_10796339, HPA058769: AB_2683814, HPA071948: AB_2686475" "unprognostic (7.55e-3)" "unprognostic (7.74e-3)" "unprognostic (4.52e-4)" "unprognostic (5.12e-3)" "unprognostic (1.38e-1)" "unprognostic (5.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.53e-1)" "unprognostic (6.50e-2)" "unprognostic (9.01e-3)" "unprognostic (5.29e-2)" "unprognostic (4.68e-4)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "unprognostic (7.06e-2)" "unprognostic (2.34e-2)" 1.4 0.7 2.5 0.2 4.9 0.0 0.2 1.2 3.7 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.9 5.4 1.8 0.0 1.9 0.2 0.2 0.6 1.5 0.0 0.1 0.0 1.7 0.1 2.3 0.2 0.1 0.4 0.1 0.7 0.0 0.1 0.0 0.4 2.6 0.0 0.0 1.1 2.6 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.9 1.2 3.7 5.4 1.8 0.6 1.5 2.3 2.6 2.6 0.9 1.0 0.0 0.6 19.6 0.0 0.3 0.0 0.4 0.0 4.2 0.1 0.3 3.7 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.5 11.3 0.5 1.1 0.1 0.0 3.4 44.6 0.0 0.1 0.8 0.0 0.3 1.3 0.1 0.0 5.9 0.1 0.0 460.0 0.0 0.0 0.0 0.3 11.4 0.9 0.1 1.8 8.4 0.0 2.8 0.0 299.6 4.7 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.4 0.0 0.1 0.1 5.0 7.7 0.0 0.0 0.3 0.3 1.6 0.0 0.0 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 3800000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: AB_2667469" "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 169.3 27.0 12.4 34.4 11.8 4.9 115.9 13.3 12.7 77.4 17.1 104.9 47.4 97.1 21.5 64.7 66.4 46.1 97.5 10.2 14.7 56.8 39.5 87.2 24.1 14.8 11.2 43.6 69.3 34.3 22.9 56.9 14.6 69.9 41.7 2.1 91.7 58.2 49.5 57.7 65.6 65.7 11.9 30.8 76.3 17.1 13.7 21.3 60.6 35.8 25.1 86.3 67.8 10.8 169.8 182.1 19.3 79.5 88.8 87.6 74.2 168.6 138.9 108.7 91.0 122.3 90.7 16.9 118.7 261.1 72.7 139.9 29.2 117.2 56.3 75.2 74.5 16.2 96.4 46.2 131.7 1.6 81.5 68.7 57.3 100.2 57.3 99.5 141.7 10.5 13.1 13.7 93.5 129.5 1.9 1.4 12.4 105.8 34.0 6.9 26.4 30.7 100.5 86.9 7.8 43.0 105.9 152.6 67.4 47.5 125.3 8.7 187.9 156.6 119.1 77.7 147.8 10.7 9.1 7.2 124.7 4.1 138.8 0.1 0.9 0.0 0.9 2.0 0.4 4.8 2.1 0.9 1.1 3.8 0.7 0.4 0.5 0.0 1.7 1.0 1.9 1.5 12.4 11.8 13.3 12.7 10.2 14.7 14.8 11.2 14.6 11.9 13.7 10.8 133.7 125.0 35.9 5.5 20.8 39.8 38.2 27.8 31.9 4.1 44.0 33.0 75.4 48.6 36.3 86.5 0.0 57.8 2.5 159.0 21.5 62.3 17.4 26.3 44.4 78.0 39.5 13.5 2.5 52.0 28.4 51.8 66.3 75.5 12.0 25.4 83.6 38.5 20.0 5.0 3.8 111.8 14.2 14.5 43.4 11.4 42.3 16.7 64.0 15.0 20.3 5.6 0.0 2.5 1.0 92.8 88.7 48.5 12.8 64.7 92.8 15.4 12.9 2.1 118.3 37.7 90.6 9.4 7.5 39.5 42.6 47.6 10.0 10.6 88.1 39.2 MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.6;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "dendritic cells: 81.3;Langerhans cells: 65.1;Macrophages: 74.2;monocytes: 392.2;NK-cells: 252.4;T-cells: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 52.6;HEL: 64.1;HL-60: 39.9;JURKAT: 85.9;MOLT-4: 97.3;NB-4: 52.1;THP-1: 68.6;U-937: 57.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Nucleoplasm "HPA021252: AB_1854254" "unprognostic (2.74e-2)" "prognostic favorable (8.26e-4)" "unprognostic (5.20e-3)" "unprognostic (9.91e-3)" "unprognostic (1.27e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.54e-3)" "unprognostic (6.47e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (8.71e-8)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (7.92e-2)" 2.2 0.8 0.4 16.6 0.3 43.6 1.0 0.3 0.6 0.8 0.3 2.0 3.3 0.7 0.3 1.5 1.2 3.5 0.9 0.3 1.0 0.9 1.3 12.0 25.1 1.4 0.7 0.3 0.7 0.1 0.5 1.2 0.6 1.1 1.8 0.0 2.3 0.7 0.3 0.9 7.8 2.8 0.6 19.0 3.3 0.4 1.6 27.2 1.6 0.4 14.8 6.1 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 52.6 0.0 64.1 2.7 0.0 0.0 39.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 85.9 0.0 0.0 0.0 0.0 97.3 52.1 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 57.3 0.0 41.5 58.3 18.5 61.5 95.5 38.4 27.7 40.5 55.6 42.7 18.9 14.1 29.6 6.0 23.9 129.8 4.5 79.9 79.9 0.4 0.3 0.3 0.6 0.3 1.0 1.4 0.7 0.6 0.6 1.6 0.8 0.9 3.2 7.7 0.0 55.7 2.8 0.4 0.0 0.0 0.2 1.2 1.3 1.1 1.5 1.3 0.0 0.0 0.2 81.3 0.2 0.0 0.3 0.6 0.3 0.5 1.0 0.0 6.3 0.1 1.1 0.3 2.3 2.0 0.6 30.4 0.4 2.2 1.4 10.5 3.3 0.0 0.2 0.0 58.7 65.1 1.6 0.0 74.2 3.6 0.0 392.2 0.3 252.4 0.5 0.0 0.2 0.1 0.4 33.4 0.4 0.0 0.6 0.7 0.2 6.6 2.0 1.4 3.8 1.2 0.2 1.7 0.1 87.1 1.2 0.1 0.2 MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 55.5;Exocrine glandular cells: 11.8;Pancreatic endocrine cells: 10.3;Proximal tubular cells: 9.2;Syncytiotrophoblasts: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 35.4;SK-BR-3: 56.8;T-47d: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" 8.1 6.2 30.6 3.4 30.3 2.0 3.4 27.1 31.5 1.7 16.8 19.0 27.3 2.7 1.9 5.3 4.5 6.1 3.9 28.4 28.2 14.5 41.5 3.2 1.5 34.0 33.5 1.0 11.1 1.5 5.5 19.8 28.7 3.2 16.2 3.4 5.6 5.2 84.2 3.7 25.8 4.4 24.5 1.4 15.0 1.3 31.8 1.1 1.9 39.2 1.8 3.1 2.4 24.2 8.1 5.5 9.2 5.6 3.8 1.2 19.7 1.4 1.1 0.8 1.3 13.9 8.3 4.4 15.9 1.4 4.0 16.4 6.7 15.5 1.1 1.4 3.6 0.8 24.6 35.4 0.5 0.8 2.7 1.8 7.2 2.6 3.0 4.3 3.8 3.3 1.1 4.2 2.0 13.4 2.5 1.2 5.5 27.4 4.4 4.0 4.6 1.3 4.9 2.9 1.3 13.0 10.8 56.8 0.9 7.8 52.8 1.3 3.2 1.8 11.0 1.6 3.5 2.8 6.5 1.6 1.6 3.1 1.6 0.4 0.1 0.2 0.7 0.1 0.5 0.2 0.4 0.4 0.0 0.2 0.2 0.3 0.3 0.4 0.1 0.1 0.6 0.1 30.6 30.3 27.1 31.5 28.4 28.2 34.0 33.5 28.7 24.5 31.8 24.2 3.9 9.6 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 0.0 2.5 3.7 0.0 55.5 0.3 0.0 1.9 5.7 0.0 3.4 0.7 2.1 0.0 0.0 0.0 11.8 3.6 1.1 0.0 2.0 1.3 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 9.2 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 17.4 0.3 0.1 0.0 0.0 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 NADK FLJ13052 ENSG00000008130 "NAD kinase" O95544 1 1751232-1780457 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 506.2" "Group enriched" "Detected in all" 7 "granulocytes: 506.2;monocytes: 162.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048909, HPA053368" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "HPA048909: AB_2680553, HPA053368: AB_2682130" "unprognostic (1.29e-1)" "unprognostic (4.29e-1)" "unprognostic (7.07e-2)" "unprognostic (6.82e-2)" "unprognostic (1.98e-1)" "unprognostic (1.58e-2)" "unprognostic (3.32e-1)" "unprognostic (9.03e-2)" "unprognostic (7.81e-2)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (4.54e-3)" "unprognostic (1.40e-1)" "unprognostic (5.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" 53.6 81.8 24.8 37.5 26.6 100.7 44.7 22.1 29.0 28.6 27.8 45.1 38.0 30.9 13.3 29.9 36.1 23.3 28.7 24.1 24.3 30.2 134.0 40.3 41.2 25.4 24.6 37.2 38.9 17.2 26.4 26.0 25.0 32.9 25.4 10.9 40.2 17.4 19.6 28.3 43.3 19.8 24.5 93.1 43.2 27.5 26.5 16.4 31.7 19.2 26.6 32.3 27.1 23.8 41.6 39.3 34.4 50.7 47.8 34.5 44.2 40.9 35.5 45.6 40.3 42.1 74.2 54.5 30.4 30.5 14.7 34.6 37.3 32.5 20.3 53.5 59.1 44.7 65.0 73.6 46.2 63.4 72.1 40.6 28.9 28.4 40.3 24.8 44.9 42.6 55.9 75.8 34.4 47.4 48.1 54.8 23.5 69.4 43.8 60.4 29.4 113.1 39.7 33.9 46.2 35.2 45.8 99.2 43.7 20.3 34.2 43.6 43.8 33.1 23.7 34.6 37.5 67.1 32.7 121.8 32.7 69.3 17.6 84.2 141.3 329.7 7.4 158.6 8.8 10.8 4.3 5.9 45.9 12.1 2.8 4.1 506.2 3.8 162.6 37.9 7.0 82.9 24.8 26.6 22.1 29.0 24.1 24.3 25.4 24.6 25.0 24.5 26.5 23.8 29.0 12.8 30.7 14.4 27.2 9.8 15.7 11.2 13.6 7.9 21.4 17.9 6.8 25.8 21.6 14.7 16.7 24.5 46.8 57.8 15.6 19.1 14.9 18.7 22.2 20.8 22.8 15.8 10.2 29.4 26.3 18.7 52.0 22.8 2.5 21.2 22.5 94.3 36.6 6.7 10.4 38.7 16.2 58.4 13.7 26.7 37.6 45.0 8.8 9.4 67.3 5.7 27.8 10.6 11.1 28.7 34.6 34.6 26.0 34.7 28.6 24.3 13.5 17.7 13.1 12.6 18.2 12.4 22.4 19.5 12.8 42.8 15.4 44.2 31.0 27.5 NANOS1 "NOS1, ZC2HC12A" ENSG00000188613 "Nanos C2HC-type zinc finger 1" Q8WY41 10 119029714-119033730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" "Repressor, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 38.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 10.2;Cardiomyocytes: 11.3;Cone photoreceptor cells: 10.4;Muller glia cells: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 80.4;SK-BR-3: 46.7;SK-MEL-30: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB012219 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB012219: " "prognostic unfavorable (1.52e-4)" "unprognostic (1.17e-1)" "unprognostic (1.50e-3)" "unprognostic (1.59e-3)" "unprognostic (7.07e-3)" "unprognostic (2.01e-1)" "unprognostic (2.19e-2)" "unprognostic (4.76e-3)" "unprognostic (1.97e-1)" "unprognostic (2.70e-1)" "unprognostic (8.22e-3)" "unprognostic (8.79e-2)" "unprognostic (2.64e-4)" "unprognostic (7.89e-2)" "unprognostic (6.99e-2)" "unprognostic (2.78e-2)" "unprognostic (2.52e-3)" 9.5 11.3 7.4 0.3 7.3 0.2 8.3 7.4 7.7 1.9 5.0 2.9 0.3 2.1 1.7 1.0 1.0 0.2 10.3 5.9 11.8 4.6 0.3 1.1 0.4 8.8 8.9 0.3 2.2 0.3 2.8 6.3 8.5 1.0 0.4 4.1 1.3 0.9 38.6 1.6 0.9 1.8 7.1 0.3 3.4 1.9 9.2 0.3 7.1 1.7 0.3 3.3 1.0 10.9 16.4 1.3 2.2 0.4 7.4 1.1 9.7 0.4 0.5 0.4 0.2 2.0 5.6 8.7 2.2 0.1 0.0 5.8 2.7 2.9 0.7 2.6 6.6 0.2 3.8 1.8 3.5 1.0 0.0 1.5 11.7 0.1 1.6 2.4 0.4 3.0 1.7 1.0 0.5 2.3 2.2 2.8 7.1 3.4 1.3 0.0 2.7 5.9 3.1 1.3 6.3 80.4 4.7 46.7 37.4 12.2 7.4 4.7 0.5 0.0 3.4 0.1 0.8 2.4 8.6 3.2 0.7 2.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 7.4 7.3 7.4 7.7 5.9 11.8 8.8 8.9 8.5 7.1 9.2 10.9 5.7 6.4 1.1 2.0 1.3 0.8 5.0 1.3 0.6 4.1 10.2 6.1 11.3 1.5 1.2 1.8 10.4 6.5 6.3 4.4 0.0 0.6 0.2 3.9 2.8 1.7 3.0 0.0 0.5 0.2 0.4 4.0 1.1 3.7 0.0 2.6 0.7 0.1 0.7 1.7 2.3 3.8 0.0 0.0 2.1 0.1 1.8 0.9 0.0 0.0 0.0 14.7 1.0 2.0 0.2 0.3 0.1 0.7 1.6 2.9 0.2 0.5 1.2 2.1 0.0 7.7 3.9 0.4 1.0 0.8 1.3 1.0 2.9 0.7 2.1 1.3 NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 43.5;brain: 99.0" "Cell type enhanced" "Detected in some" "Astrocytes: 126.7;Excitatory neurons: 46.0;Horizontal cells: 80.8;Inhibitory neurons: 37.6;Muller glia cells: 25.0" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 20.8;SCLC-21H: 25.8;SK-MEL-30: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 43.5 0.7 56.1 0.1 46.4 0.0 1.6 42.9 99.0 0.0 0.6 0.2 0.1 0.3 1.3 0.1 0.9 0.1 0.8 45.8 29.0 5.3 0.0 0.0 0.2 52.3 46.4 0.2 2.3 0.9 1.8 0.1 57.5 1.0 0.1 3.7 2.3 1.6 5.7 1.0 0.2 0.2 33.0 0.3 0.4 9.0 88.8 0.2 0.3 2.5 0.0 0.0 0.0 38.9 0.1 9.2 4.9 10.0 0.9 0.0 5.7 0.2 0.0 0.2 0.0 4.1 0.3 0.0 1.9 0.0 1.5 0.1 11.1 0.0 0.1 0.0 13.2 0.1 2.1 6.6 1.5 14.5 6.9 0.0 0.2 0.0 0.0 1.8 0.0 3.4 11.5 0.0 0.4 6.2 0.2 20.8 14.1 0.0 4.1 0.7 2.3 0.4 0.2 0.5 25.8 8.6 6.6 0.0 21.4 0.8 0.7 8.3 0.0 0.0 3.3 0.1 5.6 0.0 0.0 0.2 0.0 6.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 56.1 46.4 42.9 99.0 45.8 29.0 52.3 46.4 57.5 33.0 88.8 38.9 0.5 0.0 0.0 126.7 0.0 0.3 0.0 0.0 0.0 14.5 1.4 2.2 2.6 0.0 0.0 1.8 6.2 0.0 5.4 0.0 0.0 4.6 1.1 1.7 0.1 0.4 1.8 0.0 46.0 0.6 0.1 0.2 0.0 1.0 0.0 21.9 0.0 0.0 0.8 80.8 37.6 0.0 0.0 0.0 0.3 3.8 0.0 0.7 10.6 17.8 0.0 25.0 0.0 23.1 15.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.8 0.5 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 NDUFA4L2 "COXFA4L2, FLJ26118, NUOMS" ENSG00000185633 "NDUFA4 mitochondrial complex associated like 2" Q9NRX3 12 57234903-57240715 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 304.9" "Group enriched" "Detected in many" 4 "Muller glia cells: 627.0;Sertoli cells: 1130.7;Smooth muscle cells: 525.6" "Cancer enriched" "Detected in all" 5 "renal cancer: 356.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "AN3-CA: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-3)" "unprognostic (3.23e-3)" "unprognostic (5.06e-2)" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (3.53e-1)" "unprognostic (6.67e-2)" "unprognostic (5.79e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.10e-3)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (2.74e-2)" 85.6 14.0 41.6 6.8 40.1 0.2 55.1 41.4 61.5 109.3 36.8 17.4 5.8 20.7 2.4 304.9 15.5 17.1 180.1 40.3 41.1 47.6 20.9 62.6 5.8 43.0 42.7 14.0 14.5 12.1 30.9 71.7 48.8 27.3 1.9 29.4 55.8 9.8 43.8 206.9 14.2 7.5 38.9 74.1 18.0 8.7 43.5 3.2 54.5 29.2 4.8 27.7 183.5 45.4 0.9 1.3 0.3 133.9 5.4 3.1 0.4 2.1 1.5 0.6 1.3 0.0 1.5 5.5 5.6 2.1 0.1 1.2 0.7 1.0 0.0 3.0 0.2 0.6 0.3 0.1 18.6 4.1 2.0 12.0 2.5 0.2 4.7 0.9 0.0 7.6 0.5 7.2 0.4 2.7 1.1 0.2 0.3 0.6 2.4 2.1 1.0 11.0 0.1 0.1 7.1 2.5 0.2 0.3 4.7 0.1 1.5 14.5 0.6 1.2 0.1 1.1 0.7 10.0 3.5 2.5 4.9 9.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 41.6 40.1 41.4 61.5 40.3 41.1 43.0 42.7 48.8 38.9 43.5 45.4 156.0 0.0 0.5 2.6 2.6 151.2 0.9 89.2 6.8 30.6 2.6 5.8 1.2 0.0 24.8 0.0 18.8 1.0 0.9 0.1 0.0 1.6 1.7 0.4 3.0 91.8 0.0 0.0 2.2 0.0 1.5 21.5 4.6 0.3 8.9 0.1 2.9 1.3 1.9 11.8 3.0 0.2 54.9 0.0 28.9 3.0 3.1 2.0 30.2 18.7 1.0 627.0 0.0 0.5 0.4 4.7 0.0 2.2 1.4 2.0 0.1 0.3 6.2 25.7 1130.7 13.0 525.6 12.3 5.5 20.3 161.4 1.1 1.9 2.5 0.2 1.4 NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "granulocytes: 11.4;Hofbauer cells: 17.0;Kupffer cells: 53.9;Macrophages: 27.2;monocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cell line enriched" "Detected in some" 4 "THP-1: 37.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" 6.3 1.9 1.5 12.4 1.9 30.9 1.1 1.5 2.2 1.8 2.0 1.5 1.3 0.6 0.6 1.3 2.0 2.3 1.3 1.8 2.4 1.2 2.3 7.5 5.5 3.1 2.2 0.3 0.8 0.3 0.6 2.9 2.9 0.9 1.2 0.1 0.8 1.4 0.4 1.4 2.3 2.9 2.3 19.9 1.1 0.7 2.9 2.1 0.7 1.5 2.1 3.1 0.7 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 5.8 0.0 0.0 0.1 0.0 0.4 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.3 48.2 2.8 0.1 32.5 0.2 0.0 0.1 0.0 16.5 0.1 0.0 0.0 90.4 0.0 31.1 0.3 0.0 25.4 1.5 1.9 1.5 2.2 1.8 2.4 3.1 2.2 2.9 2.3 2.9 3.0 0.4 0.0 3.7 0.0 0.5 0.9 0.7 0.9 0.6 0.2 0.4 0.0 0.6 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.8 0.4 0.2 0.5 1.2 0.0 0.7 0.2 0.1 0.5 0.0 0.3 11.4 0.0 0.7 0.6 17.0 0.0 0.6 0.0 0.0 53.9 8.2 5.6 0.3 27.2 0.0 8.4 44.6 0.0 0.0 2.0 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.5 0.5 0.8 0.7 0.0 1.0 0.3 1.3 0.4 0.0 0.5 NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 68.3;brain: 58.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 319.5;Club cells: 164.2;Ductal cells: 123.9" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 90.1" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.0" "Group enriched" "Detected in all" 5 "olfactory bulb: 43.3;pons: 14.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" 68.3 24.0 19.9 4.1 17.9 6.0 30.7 18.2 23.5 8.3 16.3 5.3 3.1 7.5 4.9 6.9 8.6 4.8 5.4 21.4 58.9 10.7 3.1 6.2 5.7 29.3 22.7 7.1 8.4 4.5 9.8 1.9 26.2 5.0 2.9 3.0 7.4 2.5 2.5 4.9 4.1 4.7 22.4 4.8 5.5 11.9 21.4 4.5 17.7 3.1 3.0 8.5 6.5 44.7 90.1 35.3 6.1 1.3 17.1 7.7 0.8 4.7 10.5 12.5 16.6 12.9 23.5 3.4 12.9 14.7 0.1 15.0 34.0 7.0 7.4 30.3 36.7 12.4 13.2 59.7 4.4 8.2 13.6 7.6 2.8 18.2 7.2 7.6 17.9 23.3 0.2 1.4 6.9 55.2 8.8 30.0 22.9 18.0 8.9 25.7 0.1 38.7 11.5 7.3 3.1 34.6 8.2 5.1 40.5 6.0 5.9 33.8 4.0 2.4 10.3 10.3 7.9 0.7 9.9 8.2 26.3 52.9 14.1 0.0 1.0 7.8 7.9 0.7 2.9 5.9 5.9 7.7 4.5 11.3 5.8 4.1 1.6 1.8 0.5 13.4 7.6 3.4 19.9 17.9 18.2 23.5 21.4 58.9 29.3 22.7 26.2 22.4 21.4 44.7 39.0 3.2 2.7 5.5 13.6 15.6 29.5 319.5 21.6 1.9 30.7 37.6 3.5 20.0 164.2 31.3 0.0 2.4 25.3 5.3 13.7 123.9 33.7 21.3 7.3 19.6 18.6 7.4 0.6 58.2 14.1 19.7 11.2 15.6 5.7 12.0 7.5 3.7 32.3 5.0 1.2 6.5 18.3 8.8 86.4 29.0 4.4 26.0 33.8 1.9 18.5 6.5 25.7 2.0 1.0 45.2 5.1 3.8 32.5 39.3 0.8 32.0 57.8 4.1 13.1 22.5 28.6 24.0 21.6 29.5 12.8 3.1 19.7 8.2 9.1 60.6 NNAT Peg5 ENSG00000053438 Neuronatin Q16517 20 37521206-37523690 "Predicted membrane proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 11 "pituitary gland: 1586.9" "Cell type enhanced" "Detected in many" "Early spermatids: 42.0;Excitatory neurons: 33.9;Late spermatids: 65.5;Muller glia cells: 177.1" "Group enriched" "Detected in many" 16 "glioma: 87.5;testis cancer: 55.0;urothelial cancer: 37.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 22 "SH-SY5Y: 720.8" "Low region specificity" "Detected in all" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (1.18e-2)" "unprognostic (7.41e-3)" "unprognostic (1.85e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (9.66e-4)" "unprognostic (7.08e-2)" "unprognostic (1.42e-1)" "unprognostic (2.36e-1)" "unprognostic (4.05e-2)" "unprognostic (7.52e-2)" "unprognostic (4.94e-2)" "unprognostic (1.64e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (1.96e-1)" "unprognostic (1.15e-3)" "unprognostic (5.90e-2)" 27.4 15.1 109.4 2.5 141.4 2.5 32.5 15.8 65.2 7.4 56.2 76.2 4.0 4.9 0.2 3.4 3.6 4.7 2.7 105.8 70.9 1.6 2.0 2.1 1.4 45.7 49.7 1.5 1.4 0.0 1586.9 106.5 49.3 4.4 4.0 31.4 6.6 0.6 13.5 5.1 14.6 5.1 22.3 1.4 16.8 5.0 93.5 11.1 2.0 0.3 0.1 14.5 5.6 29.6 2.2 1.7 12.6 1.7 0.0 0.0 4.5 0.5 0.0 0.1 0.0 4.2 2.2 1.0 0.7 0.0 0.2 10.2 0.0 0.0 0.0 0.1 0.3 0.3 12.9 2.4 3.2 1.3 1.1 2.9 0.0 0.0 0.0 0.2 32.5 0.3 0.2 2.4 0.1 1.0 5.7 1.3 0.9 0.3 1.6 0.5 4.0 0.5 0.0 20.6 1.9 720.8 1.1 5.0 0.0 0.6 1.3 0.2 0.8 5.7 0.8 1.6 1.1 0.9 0.2 0.1 1.7 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 109.4 141.4 15.8 65.2 105.8 70.9 45.7 49.7 49.3 22.3 93.5 29.6 0.3 0.0 0.0 1.6 0.2 4.0 0.8 0.1 19.9 4.5 0.3 5.8 0.1 0.0 0.7 0.0 0.0 0.6 0.3 0.1 0.0 0.2 42.0 0.1 3.0 21.6 0.0 0.0 33.9 0.0 1.1 3.1 0.0 0.1 1.3 2.2 0.0 0.0 1.6 0.0 9.6 0.2 0.0 0.3 1.1 65.5 0.6 0.1 1.8 4.7 0.0 177.1 0.0 2.0 1.8 0.0 0.0 1.2 0.0 2.5 0.0 0.0 1.1 6.5 0.0 1.4 1.9 1.5 5.6 3.6 1.0 0.3 0.1 0.1 0.0 4.8 NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.1;tongue: 384.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 344.3;Hepatocytes: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975" Enhanced Approved Mitochondria,Cytosol NA NA 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "CAB004975: AB_425908, HPA004829: AB_1079495" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favorable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" 26.0 16.5 12.8 11.8 16.0 15.0 13.7 11.2 21.7 16.4 34.9 25.9 17.2 11.0 16.7 16.8 10.7 15.0 137.7 16.1 11.5 57.0 116.4 13.2 16.5 10.3 12.0 10.1 17.8 55.6 9.6 12.7 9.5 18.3 27.8 12.9 26.6 18.2 239.1 10.4 16.1 20.6 9.3 11.5 31.2 6.2 15.8 26.8 31.1 384.0 17.2 17.3 9.3 15.1 15.4 12.6 30.5 59.6 44.0 50.3 9.9 17.5 39.8 24.8 20.8 19.0 30.4 18.5 21.5 43.9 22.3 16.6 120.5 5.4 27.4 31.1 33.6 24.0 70.7 23.8 27.5 50.2 43.1 37.9 17.5 16.3 18.6 42.6 56.3 22.7 21.4 81.3 60.0 15.1 55.8 35.8 6.4 0.1 15.2 54.7 73.8 70.8 58.0 15.5 44.2 37.7 62.9 1.4 46.7 6.9 47.7 58.3 23.2 29.5 28.3 12.0 8.3 36.1 45.1 26.5 7.1 68.8 22.1 12.5 18.2 16.0 16.7 23.0 17.1 12.0 17.1 15.5 32.0 12.0 15.5 14.7 2.9 23.2 24.7 9.1 22.2 19.3 12.8 16.0 11.2 21.7 16.1 11.5 10.3 12.0 9.5 9.3 15.8 15.1 12.0 54.5 37.8 60.7 19.6 11.5 9.5 19.0 13.1 17.9 9.6 6.3 344.3 38.6 27.0 27.6 35.5 8.7 20.4 34.4 27.4 14.4 16.7 18.5 16.6 19.2 19.9 34.9 124.8 10.7 2.3 27.2 23.9 25.1 25.2 26.8 21.0 314.3 25.0 6.7 110.6 22.6 20.3 40.6 11.9 4.6 14.9 19.8 14.2 45.9 25.9 12.5 35.0 77.9 63.4 9.5 16.7 19.2 20.0 11.7 23.6 21.7 18.1 12.8 0.0 14.0 20.1 4.0 1.4 17.6 8.1 2.1 20.9 18.8 28.9 9.9 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.1" "Group enriched" "Detected in many" 6 "Adipocytes: 99.6;Endothelial cells: 52.5;Hepatic stellate cells: 132.8" "Group enriched" "Detected in all" 4 "ovarian cancer: 39.2;renal cancer: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 158.5" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 67.1 8.7 1.7 3.4 1.5 0.0 44.3 1.4 1.4 8.8 1.5 10.1 1.5 31.0 5.5 4.3 36.4 5.9 15.8 1.3 1.4 28.8 4.3 24.2 2.3 1.5 1.5 27.7 3.9 8.4 3.8 17.7 1.5 4.4 2.0 0.1 3.7 12.1 7.2 6.6 9.3 9.7 1.8 2.2 8.8 1.3 2.4 1.9 14.0 11.1 1.3 12.8 9.7 1.4 0.0 1.3 0.1 0.0 158.5 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 28.0 0.0 19.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 15.9 0.0 0.0 2.1 0.0 0.1 0.0 1.9 0.0 5.7 1.0 0.1 0.0 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.5 1.4 1.4 1.3 1.4 1.5 1.5 1.5 1.8 2.4 1.4 99.6 0.0 6.9 0.0 0.2 1.5 0.5 0.0 0.6 0.0 0.5 0.5 4.5 2.8 0.0 14.7 0.0 0.2 0.1 0.0 0.0 0.7 9.1 6.2 8.8 52.5 0.0 0.0 0.0 0.0 1.3 15.2 0.0 15.4 0.0 0.0 132.8 2.4 0.3 0.0 0.0 0.0 0.0 4.7 4.0 11.5 10.2 0.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.0 0.0 4.1 0.0 0.5 0.0 4.0 0.0 0.0 0.0 1.4 2.2 0.5 0.1 0.2 1.0 0.7 0.3 1.4 0.2 0.0 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Excitatory neurons: 69.1;Inhibitory neurons: 68.9;Microglial cells: 34.7;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 30.9;ASC TERT1: 21.1;BJ hTERT+: 20.2;HHSteC: 20.1;HSkMC: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 12.4 8.2 9.3 1.7 9.4 0.3 10.3 14.4 9.9 25.7 7.7 15.6 1.8 20.5 8.7 3.2 15.1 3.2 12.8 9.1 11.4 6.7 8.6 9.1 2.3 11.8 9.4 9.4 3.2 1.3 13.8 4.7 11.5 10.9 2.8 4.1 5.3 6.5 10.8 8.3 7.5 9.9 8.2 4.9 7.8 4.8 10.7 2.2 6.0 8.6 1.7 12.1 14.7 7.9 0.0 2.9 2.2 0.0 30.9 21.1 1.9 9.3 20.2 7.0 6.4 4.5 4.3 1.8 3.0 17.9 12.8 1.2 3.6 0.2 6.1 2.2 1.0 1.8 4.3 3.4 20.1 0.4 0.0 23.8 1.8 8.9 0.6 7.6 12.7 2.5 0.7 0.2 13.4 1.0 0.5 0.8 3.5 1.0 3.7 2.4 0.2 0.5 1.8 1.4 1.1 0.7 0.4 0.1 0.6 3.8 0.2 0.0 8.2 8.5 7.8 3.2 1.2 0.5 0.6 4.8 10.4 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 9.3 9.4 14.4 9.9 9.1 11.4 11.8 9.4 11.5 8.2 10.7 7.9 2.7 3.2 3.4 35.6 0.0 1.1 0.6 0.6 1.2 5.1 0.7 1.4 0.7 1.5 0.3 0.0 2.1 0.4 0.5 0.7 0.0 0.6 0.3 1.4 9.2 4.4 0.0 0.0 69.1 0.8 0.2 7.2 0.5 2.0 1.3 9.6 6.1 4.5 0.4 3.3 68.9 0.7 0.0 0.3 2.1 0.3 9.3 0.3 0.0 34.7 0.0 6.8 0.0 51.8 16.3 0.6 3.6 7.9 0.2 2.7 0.2 0.6 1.1 2.2 0.0 5.1 3.4 4.5 3.1 0.1 1.6 0.3 0.7 0.8 1.1 0.4 NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.8;liver: 38.6;pancreas: 61.1" "Cell type enriched" "Detected in many" 5 "Granulosa cells: 276.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "A549: 25.0;CACO-2: 6.2;HAP1: 14.9;HMC-1: 6.4;HUVEC TERT2: 20.4" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Not detected" "Not detected" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" 5.4 0.4 0.5 2.6 0.2 0.9 3.7 0.5 0.3 3.4 0.2 11.9 17.4 3.3 1.4 0.9 2.2 8.0 1.0 0.3 2.8 0.7 38.6 2.7 2.1 0.7 0.6 1.0 61.1 0.4 0.1 0.4 0.8 1.6 13.1 0.2 0.5 0.8 1.1 1.1 17.8 4.3 0.4 0.2 1.3 0.8 0.8 0.5 0.9 0.7 1.4 1.8 1.2 0.7 0.0 25.0 0.0 0.1 0.0 0.2 0.6 0.0 0.4 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.7 0.7 14.9 0.0 0.0 3.3 1.1 0.0 0.3 2.7 0.5 0.1 6.4 0.1 0.0 0.0 0.1 0.0 20.4 0.1 0.0 0.3 0.0 0.6 0.0 0.4 0.9 0.0 0.3 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.7 4.7 0.3 0.1 1.0 0.2 0.1 0.2 3.4 2.3 2.6 0.3 0.2 0.1 3.2 0.4 0.4 0.2 0.2 0.2 0.3 0.3 0.3 0.1 0.4 0.4 0.3 1.5 0.5 0.2 0.5 0.4 0.1 0.5 0.2 0.5 0.3 0.3 2.8 0.7 0.6 0.8 0.4 0.8 0.7 23.7 0.0 1.7 0.3 0.2 1.9 0.1 0.0 0.0 0.2 0.2 0.0 9.9 32.9 0.0 0.0 0.0 0.0 0.3 37.5 0.0 38.2 0.4 0.3 0.3 32.4 4.9 2.7 0.4 54.5 0.0 0.8 0.0 0.2 13.3 276.2 38.6 38.5 0.1 0.0 0.6 13.8 0.0 4.9 1.5 0.3 0.6 0.6 0.0 0.0 3.1 0.0 0.0 1.0 0.3 22.0 21.8 0.0 1.2 0.3 49.9 0.0 0.8 0.3 0.0 0.5 6.1 0.1 0.1 0.0 1.4 0.0 0.3 0.1 32.3 0.2 NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 366.0;Endothelial cells: 174.4;Hepatic stellate cells: 184.6;Sertoli cells: 282.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 444.6;hTERT-RPE1: 371.6;TIME: 369.5;U-87 MG: 425.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" 125.2 42.3 9.3 43.3 9.4 3.7 62.2 0.0 26.0 36.9 13.3 26.6 21.3 51.6 35.7 19.7 34.5 54.1 80.8 48.6 9.1 52.7 53.1 63.7 23.7 4.0 3.9 43.0 33.0 24.4 9.0 133.7 2.1 21.3 23.6 11.6 19.3 38.4 55.9 22.1 21.0 55.9 5.7 66.7 18.6 12.9 13.4 18.2 49.7 46.6 12.4 35.3 20.0 10.7 57.4 217.8 11.1 1.1 204.8 224.7 1.3 224.4 216.2 109.6 118.2 28.9 132.4 1.1 26.6 444.6 116.8 15.8 13.8 65.2 89.3 0.7 11.2 0.6 24.5 48.7 74.3 20.8 1.6 277.3 11.2 261.7 116.8 371.6 304.0 1.4 0.7 1.4 221.3 96.8 1.4 3.9 5.5 11.9 204.2 9.6 24.8 1.2 109.7 1.3 5.1 2.7 23.0 17.5 0.9 9.2 1.0 3.3 369.5 156.4 36.9 193.0 153.8 0.7 1.1 0.7 425.2 26.4 143.5 0.4 2.5 0.5 0.6 0.4 1.0 0.7 0.7 0.6 2.3 0.6 0.6 0.6 0.4 1.2 0.3 39.3 0.6 0.9 9.3 9.4 0.0 26.0 48.6 9.1 4.0 3.9 2.1 5.7 13.4 10.7 366.0 0.0 20.2 80.3 4.3 15.7 10.6 5.5 7.4 10.5 4.2 5.5 67.6 28.6 13.0 18.4 4.2 61.5 29.4 0.6 1.9 57.9 1.3 11.3 116.9 174.4 4.2 3.2 105.4 18.9 13.4 58.5 6.6 11.0 7.6 62.3 184.6 12.5 135.4 0.0 14.4 1.8 16.2 62.7 33.3 5.5 42.3 46.0 12.4 78.7 5.8 3.4 0.0 11.6 2.3 15.4 0.0 21.1 1.6 4.1 3.0 59.8 5.4 0.9 282.7 13.1 117.9 0.2 1.3 2.7 10.5 67.2 3.8 61.1 1.5 3.3 NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 53.0;Hepatocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Lipid droplets" "HPA000248: AB_1079507, HPA000571: AB_1079506" "unprognostic (1.84e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.03e-1)" "unprognostic (5.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.62e-2)" "unprognostic (2.63e-1)" "prognostic favorable (6.09e-5)" "unprognostic (3.53e-2)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (4.79e-2)" 24.0 38.8 13.2 10.2 12.6 8.9 20.2 14.2 13.3 20.3 13.7 13.9 17.6 13.6 44.5 51.7 14.9 7.9 22.4 13.7 14.3 14.9 50.4 12.9 9.1 16.8 15.4 10.3 10.6 12.9 8.8 10.3 18.5 14.8 13.5 10.4 16.7 21.3 10.1 22.6 24.2 12.5 13.4 9.5 13.8 8.9 15.2 9.9 13.3 10.9 18.1 12.1 24.1 15.1 135.6 48.9 65.5 33.8 54.9 41.5 36.2 26.3 35.2 46.9 59.3 68.5 71.7 67.0 86.0 35.9 174.2 67.6 85.5 122.1 41.3 22.0 49.5 27.9 44.7 70.3 39.8 27.6 21.1 51.1 46.3 92.2 23.0 20.2 44.2 28.7 46.4 29.1 36.1 60.1 27.3 35.8 26.0 67.4 58.1 19.9 47.4 54.6 98.9 55.7 23.4 26.5 23.4 34.6 28.4 44.9 23.1 35.0 38.7 21.6 35.4 52.3 51.0 40.9 29.4 114.9 40.0 42.4 20.8 21.0 19.6 18.7 16.3 18.7 16.4 19.1 16.1 14.1 19.4 15.1 11.6 12.7 2.2 19.7 14.2 17.4 20.4 15.2 13.2 12.6 14.2 13.3 13.7 14.3 16.8 15.4 18.5 13.4 15.2 15.1 7.1 12.8 16.7 5.9 6.3 10.8 12.8 53.0 10.8 4.3 11.7 6.1 25.0 15.7 29.0 12.9 0.0 21.5 6.1 9.6 9.8 20.1 13.3 15.5 6.6 9.2 6.0 13.0 2.2 20.3 22.0 9.0 8.2 15.5 8.2 14.0 7.5 55.0 18.6 1.7 2.2 10.2 26.4 8.7 9.6 8.0 8.4 7.9 5.4 1.0 11.0 10.6 7.2 2.5 5.7 21.4 11.9 9.1 11.3 10.4 25.2 16.5 25.4 6.2 0.0 5.9 12.5 3.7 7.8 19.4 12.1 18.6 5.3 25.1 11.2 16.4 NTSR2 NTR2 ENSG00000169006 "Neurotensin receptor 2" O95665 2 11658178-11670195 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 58 "brain: 85.4;choroid plexus: 43.7" "Cell type enriched" "Detected in some" 32 "Astrocytes: 32.7" "Cancer enriched" "Detected in single" 15 "glioma: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (5.40e-2)" "unprognostic (2.30e-2)" "unprognostic (2.36e-2)" "unprognostic (5.32e-2)" "unprognostic (2.23e-1)" "unprognostic (1.80e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-1)" "unprognostic (1.64e-1)" 0.5 0.9 74.8 0.0 84.2 0.0 0.2 67.7 78.2 0.0 43.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.7 75.8 0.0 0.0 0.0 0.0 65.8 85.4 1.1 0.2 0.0 0.2 0.0 68.9 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 60.5 0.0 0.0 0.2 82.9 0.0 0.0 0.0 0.0 0.0 0.0 60.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 84.2 67.7 78.2 65.7 75.8 65.8 85.4 68.9 60.5 82.9 60.8 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NWD2 KIAA1239 ENSG00000174145 "NACHT and WD repeat domain containing 2" Q9ULI1 4 37244743-37449463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.4;brain: 5.9" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 91.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046911 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046911: AB_2679861" "unprognostic (1.14e-2)" "unprognostic (3.12e-2)" "unprognostic (2.53e-1)" "unprognostic (5.47e-2)" "unprognostic (9.42e-2)" "unprognostic (2.55e-1)" "unprognostic (5.15e-2)" "unprognostic (1.63e-2)" "unprognostic (7.47e-2)" "unprognostic (1.00e-1)" "unprognostic (7.00e-2)" "unprognostic (1.98e-1)" "unprognostic (1.86e-2)" "unprognostic (7.65e-2)" "unprognostic (4.36e-2)" "unprognostic (1.26e-2)" 2.4 0.0 1.0 0.0 5.9 0.0 1.1 0.0 2.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.0 0.1 0.0 0.0 0.2 4.7 0.0 0.1 0.0 0.1 0.0 2.5 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.9 0.0 2.7 1.6 1.1 0.2 4.7 2.5 0.0 0.1 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.1 0.0 4.5 1.9 0.1 2.5 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 NXNL1 "RDCVF, TXNL6" ENSG00000171773 "Nucleoredoxin like 1" Q96CM4 19 17455425-17460926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "choroid plexus: 16.2;retina: 64.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Cone photoreceptor cells: 52.1;Muller glia cells: 21.0;Rod photoreceptor cells: 109.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (2.62e-1)" "unprognostic (5.49e-1)" "unprognostic (1.81e-1)" "unprognostic (3.63e-1)" "unprognostic (1.13e-1)" 2.0 1.4 1.1 0.1 1.2 0.2 0.8 1.9 1.3 0.1 16.2 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.4 2.5 0.8 0.1 0.0 0.1 0.2 1.7 1.2 0.3 0.0 0.1 0.0 0.1 1.4 0.2 0.1 64.4 0.4 0.0 0.6 0.6 0.1 0.1 1.1 0.1 0.1 0.3 1.6 0.1 0.3 0.5 0.1 0.1 0.0 1.3 0.2 0.5 0.3 0.4 0.5 0.3 0.2 0.1 0.0 0.5 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.2 0.2 0.3 0.0 0.2 0.3 0.2 0.1 0.4 0.4 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 0.4 0.2 0.5 0.0 0.6 0.1 0.2 0.1 0.1 0.2 0.2 0.5 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.4 0.3 0.1 0.1 0.0 0.0 0.2 0.3 0.1 0.3 0.4 0.4 0.0 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.0 1.1 1.2 1.9 1.3 2.5 0.8 1.7 1.2 1.4 1.1 1.6 1.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.4 0.0 0.0 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 21.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 109.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.5" "Cell type enhanced" "Detected in many" "Early spermatids: 251.6;Late spermatids: 328.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 427.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (6.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.96e-1)" "prognostic favorable (9.29e-4)" "unprognostic (1.26e-1)" "unprognostic (3.67e-1)" "unprognostic (5.68e-2)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.37e-1)" "unprognostic (4.55e-1)" "unprognostic (1.09e-3)" "prognostic favorable (5.18e-4)" 149.0 29.6 39.6 33.9 39.5 39.7 70.8 37.2 45.8 40.1 55.9 41.9 50.0 36.1 64.7 28.4 28.0 32.4 63.0 41.7 40.2 38.0 234.5 49.0 55.9 40.9 38.6 39.9 109.6 51.1 50.2 35.5 38.3 46.9 38.6 25.1 70.4 41.6 44.2 41.4 47.8 36.6 40.1 38.3 50.0 50.8 41.6 79.4 57.7 29.5 56.4 46.9 26.3 39.1 33.5 40.2 41.8 34.8 106.1 40.2 37.9 48.0 55.4 50.5 48.4 46.1 36.3 24.7 44.6 59.4 34.5 56.0 29.8 38.6 46.9 427.6 53.2 24.1 22.5 113.0 41.5 28.5 40.6 44.2 39.7 34.9 19.7 57.2 22.8 68.5 30.9 194.8 28.0 30.1 85.1 31.9 23.4 44.2 20.1 71.2 37.7 78.4 28.2 80.1 36.6 37.2 31.8 196.6 32.9 46.3 70.8 30.8 18.7 27.4 34.0 23.6 36.8 104.2 95.3 34.5 28.2 27.6 20.6 9.3 4.7 61.1 39.4 7.7 28.3 26.4 39.3 43.3 4.2 23.1 44.2 53.7 7.7 18.4 11.6 21.1 27.7 36.6 39.6 39.5 37.2 45.8 41.7 40.2 40.9 38.6 38.3 40.1 41.6 39.1 7.6 51.3 37.2 2.9 28.7 16.4 13.7 13.1 21.6 18.5 25.9 14.5 28.9 17.2 15.3 42.3 0.0 25.9 18.4 27.3 3.9 18.4 251.6 7.2 12.6 10.3 25.9 34.1 3.4 29.2 17.9 13.9 11.2 13.8 18.4 10.5 7.5 97.8 8.3 13.5 3.8 26.8 18.3 7.5 13.0 328.9 18.6 6.0 16.0 1.9 22.1 44.9 57.7 3.5 3.2 38.8 20.8 28.6 41.2 15.2 29.2 11.9 8.0 11.2 26.3 8.5 16.5 5.8 7.6 11.5 14.3 9.3 35.6 21.0 17.7 12.4 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 243.7;Distal tubular cells: 187.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 238.7;SiHa: 319.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 52.7 15.8 30.4 16.6 34.9 13.3 18.5 23.9 32.7 13.5 15.9 19.2 8.3 14.9 17.6 26.8 12.4 15.2 245.9 36.2 27.1 53.1 1.3 8.0 21.7 19.5 21.4 13.8 5.3 48.6 14.7 5.0 20.0 25.5 21.1 23.6 18.9 29.8 28.5 23.1 12.8 36.6 19.3 11.0 34.2 13.2 25.7 76.8 27.3 42.6 25.9 15.1 13.8 24.5 35.3 1.6 27.9 33.6 84.7 45.0 0.1 62.1 38.9 50.3 30.4 5.7 23.5 91.2 15.0 47.5 25.8 20.5 77.5 55.9 58.5 78.5 9.1 63.9 238.7 11.9 36.8 125.8 20.9 42.7 15.3 49.3 82.2 24.6 46.4 81.6 13.3 114.0 58.1 4.5 105.5 6.1 6.4 0.0 24.5 82.8 78.9 68.7 41.7 2.9 27.9 28.8 319.5 0.3 38.3 2.5 0.4 27.4 28.3 39.7 51.9 68.6 50.6 18.6 16.5 3.6 59.9 90.9 30.9 1.4 1.4 4.7 11.6 1.5 13.8 10.0 11.5 12.7 6.3 7.5 13.6 10.9 0.4 11.3 2.5 2.4 21.5 6.6 30.4 34.9 23.9 32.7 36.2 27.1 19.5 21.4 20.0 19.3 25.7 24.5 8.4 6.4 9.2 37.5 19.2 14.8 11.7 12.4 17.6 14.1 18.8 14.2 243.7 7.2 14.3 11.0 2.1 7.0 18.3 5.0 187.9 5.4 19.1 11.7 18.8 9.8 13.2 23.1 71.5 0.7 11.9 21.3 20.4 31.2 9.5 8.7 6.8 0.3 38.2 13.5 84.2 18.6 12.2 1.3 7.0 8.6 6.2 5.2 16.0 26.2 4.4 11.8 10.3 66.4 46.8 4.8 5.3 7.5 31.3 12.1 2.9 27.4 5.6 21.6 13.1 9.7 24.6 35.6 19.7 27.6 21.6 6.8 26.6 8.6 18.1 9.0 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568121 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 432.1;liver: 681.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 703.8;Distal tubular cells: 588.9;Hepatocytes: 1184.0;Proximal enterocytes: 2209.9;Proximal tubular cells: 3547.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "ASC diff: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 840000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 59.2 1.1 0.8 1.7 0.8 0.0 29.8 0.7 1.6 0.0 0.6 57.8 110.4 1.2 0.2 0.4 0.9 5.0 1.0 0.7 1.4 432.1 681.4 0.2 0.3 0.7 0.9 1.6 0.4 0.0 21.1 0.3 0.8 0.2 79.8 0.5 1.1 0.2 0.4 0.9 143.9 2.9 0.6 0.3 0.9 0.0 1.3 0.1 0.8 6.5 0.0 0.8 0.1 0.8 0.0 0.0 0.0 0.0 20.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.6 0.7 1.4 0.7 0.9 0.8 0.6 1.3 0.8 0.7 0.0 0.0 0.0 21.3 0.1 0.0 0.0 15.9 0.3 0.7 0.6 1.0 61.5 0.6 90.1 0.0 0.1 0.1 703.8 588.9 0.6 0.1 1.3 1.5 2.7 53.9 40.2 0.0 0.0 0.0 2.3 19.9 8.5 8.9 0.1 29.6 1184.0 0.0 3.3 0.0 293.6 0.0 22.6 0.0 0.0 0.0 12.8 0.0 1.9 0.0 9.9 0.0 0.0 0.0 0.1 285.5 0.0 0.0 0.0 2209.9 3547.9 0.0 0.4 0.0 0.3 6.0 0.0 0.1 10.3 0.3 0.3 10.2 1.5 348.5 0.1 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900958-81911432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.7;testis: 261.7" "Group enriched" "Detected in many" 7 "Early spermatids: 763.2;Late spermatids: 2829.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 218.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Approved Nucleoplasm,Cytosol NA NA 84000 "Cluster 26: Non-specific - Mitochondria" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA023033: AB_1855094, HPA023034: AB_1855095" "unprognostic (4.05e-3)" "unprognostic (4.39e-3)" "unprognostic (3.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (9.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-1)" "unprognostic (4.24e-1)" "unprognostic (8.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "prognostic favorable (4.29e-6)" "unprognostic (1.19e-1)" "unprognostic (8.59e-2)" "unprognostic (1.63e-1)" "unprognostic (4.47e-2)" 29.7 16.8 40.0 9.5 40.1 12.1 25.2 44.4 45.8 14.9 30.4 25.5 63.9 18.0 13.5 26.3 23.9 9.9 47.7 41.2 37.7 44.0 165.7 21.3 12.0 47.0 43.0 20.9 25.3 20.2 14.4 12.0 47.3 24.2 16.7 8.6 22.3 12.1 33.5 16.3 43.0 9.6 41.3 12.8 35.4 261.7 41.0 13.5 16.2 29.3 11.9 21.2 15.1 44.0 42.6 23.9 18.8 53.1 91.8 48.0 27.9 29.9 63.2 40.7 48.0 94.0 43.0 14.8 16.0 31.1 75.3 34.5 28.6 55.1 23.5 4.5 24.3 32.1 33.3 218.2 97.8 32.5 26.0 39.8 31.4 36.8 28.4 14.5 38.6 44.0 60.6 29.6 30.8 35.7 39.3 40.1 15.1 147.2 25.9 25.4 20.2 52.4 49.2 78.8 23.9 21.9 22.4 121.7 29.0 36.5 33.9 75.3 26.1 30.0 19.7 22.9 25.0 19.3 9.1 15.3 31.2 42.8 29.9 1.5 2.4 0.9 4.6 2.6 3.0 4.2 5.5 4.7 4.5 5.6 4.5 4.6 0.7 3.3 2.1 4.4 3.6 3.1 40.0 40.1 44.4 45.8 41.2 37.7 47.0 43.0 47.3 41.3 41.0 44.0 11.5 0.0 17.3 15.0 11.1 5.4 8.1 11.7 6.8 12.5 25.1 11.0 17.0 62.9 9.6 25.8 0.0 73.1 21.0 41.6 119.3 19.5 763.2 29.0 7.5 8.7 13.9 47.8 5.3 18.3 39.7 7.7 36.2 15.8 9.5 39.6 21.8 166.0 24.1 16.8 4.6 29.1 20.3 11.8 3.3 2829.0 27.7 8.1 33.8 0.0 14.7 26.7 22.6 3.5 12.2 17.8 18.8 25.9 13.4 11.4 144.4 130.3 29.4 10.6 26.3 6.2 11.5 253.1 18.1 16.5 5.7 50.8 13.6 34.4 48.7 7.7 PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643804-14872044 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 64.5" "Cell type enhanced" "Detected in many" "Astrocytes: 171.7;Excitatory neurons: 140.5;Inhibitory neurons: 158.0;Microglial cells: 192.0;Oligodendrocyte precursor cells: 118.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 13.5" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.3" "Cell line enhanced" "Detected in many" "HL-60: 23.5;Karpas-707: 25.7;THP-1: 28.4;U-266/70: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "HPA056111: AB_2683041" "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favorable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" 64.5 1.1 1.3 12.4 2.1 10.1 12.2 13.5 2.6 3.4 0.0 25.2 2.9 0.7 0.5 2.9 0.5 3.7 4.7 1.9 2.6 3.0 25.8 10.2 14.9 2.8 1.7 0.5 8.3 0.2 4.4 7.6 1.9 8.7 10.7 0.5 14.0 1.6 0.4 0.5 6.0 1.7 2.3 8.9 2.6 9.6 2.0 7.3 0.8 2.4 7.9 8.5 1.9 2.6 0.0 2.5 5.6 9.2 10.9 0.1 2.2 0.6 0.1 0.0 0.0 8.5 0.0 0.0 0.1 0.0 2.6 0.0 8.5 0.0 0.0 0.2 18.7 0.3 13.1 17.5 3.9 23.5 0.1 0.8 0.0 0.0 0.5 0.0 0.1 6.6 20.6 25.7 0.0 0.3 4.7 11.4 7.6 3.1 4.1 11.0 2.5 17.7 0.0 1.9 8.5 15.8 2.3 14.6 5.1 2.5 0.0 28.4 0.0 0.0 1.3 0.0 0.0 28.8 9.4 0.7 0.2 4.0 1.7 0.0 0.5 2.5 1.0 0.6 2.1 0.2 3.1 2.4 0.3 0.1 6.3 5.7 3.8 0.1 1.0 0.1 3.5 1.5 1.3 2.1 13.5 2.6 1.9 2.6 2.8 1.7 1.9 2.3 2.0 2.6 1.5 16.0 8.9 171.7 6.4 0.3 0.9 0.0 0.6 1.0 0.3 0.3 11.1 0.0 6.2 1.8 0.0 1.4 26.7 11.5 1.9 0.0 19.0 0.3 5.1 4.0 1.2 12.8 140.5 5.0 2.8 9.7 7.7 0.3 36.1 0.5 4.2 64.1 7.6 0.0 158.0 13.7 0.0 13.1 3.7 13.4 1.5 15.6 0.0 192.0 10.8 6.3 8.2 118.6 5.4 1.8 22.3 9.1 28.9 3.3 0.7 2.0 3.6 0.5 0.0 3.4 3.0 48.8 19.5 0.1 0.1 2.5 60.9 0.0 9.4 1.1 PDE8B ENSG00000113231 "Phosphodiesterase 8B" O95263 5 77210449-77428256 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 124.7" "Cell type enhanced" "Detected in many" "Astrocytes: 64.9;Excitatory neurons: 183.1;Horizontal cells: 69.0;Inhibitory neurons: 276.5;Muller glia cells: 86.5;Oligodendrocyte precursor cells: 190.5" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 13.6;HeLa: 34.8;SK-BR-3: 11.1" "HPA036911, HPA036912" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA036911: AB_2675378, HPA036912: AB_10670377" "unprognostic (1.30e-1)" "unprognostic (7.95e-2)" "unprognostic (3.35e-2)" "unprognostic (7.61e-4)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-2)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.26e-2)" "unprognostic (3.98e-2)" "unprognostic (2.44e-1)" "unprognostic (9.04e-3)" "unprognostic (3.40e-2)" "unprognostic (3.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.19e-2)" 20.9 4.8 24.2 1.0 28.6 0.4 14.0 4.8 24.6 17.4 0.0 5.6 2.0 26.4 6.3 2.0 28.7 4.3 23.7 25.5 32.5 15.6 2.3 5.2 1.2 20.5 15.9 4.2 7.9 0.8 12.5 23.8 18.8 19.0 1.2 22.5 10.5 11.9 0.7 2.0 3.3 17.7 9.9 0.8 5.5 3.0 36.7 0.3 124.7 0.8 1.0 4.0 4.9 17.2 0.1 4.9 0.8 0.3 1.5 0.0 0.5 1.5 13.6 0.2 0.1 1.4 0.1 0.3 0.1 0.1 0.2 0.6 0.2 0.0 0.2 0.2 0.7 0.4 34.8 0.3 0.0 0.4 0.5 0.8 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.2 0.0 0.2 0.5 0.8 0.8 0.2 0.1 0.6 0.9 0.4 0.0 0.2 5.4 1.0 2.3 11.1 0.7 0.7 1.8 0.9 0.5 0.3 0.3 0.2 0.5 0.7 0.5 0.4 1.2 0.5 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 24.2 28.6 4.8 24.6 25.5 32.5 20.5 15.9 18.8 9.9 36.7 17.2 0.8 3.2 2.8 64.9 0.3 0.4 2.0 0.1 0.0 10.8 5.8 3.0 28.0 2.8 1.6 1.8 54.2 0.0 0.2 0.1 0.0 2.3 6.8 15.3 2.1 4.5 4.9 0.0 183.1 0.0 0.1 3.8 0.0 7.9 1.3 1.8 2.9 0.1 0.4 69.0 276.5 1.0 0.0 1.0 1.6 5.1 5.9 0.9 1.8 10.3 0.1 86.5 0.0 190.5 45.5 0.2 0.4 0.0 0.3 29.1 0.2 0.7 0.7 5.8 6.6 1.8 7.7 1.1 2.6 0.5 1.1 0.0 0.1 8.8 1.2 4.2 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 508.8;tongue: 770.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 479.9;Distal tubular cells: 354.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favorable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 93.0 69.0 62.1 37.9 66.9 88.1 63.1 66.2 91.5 55.9 84.4 112.6 87.0 53.1 78.9 76.8 49.1 29.3 508.8 68.2 67.0 174.1 118.3 47.2 36.6 64.5 62.7 50.6 83.4 161.0 48.7 43.1 65.0 48.4 104.4 90.1 109.7 63.4 459.0 60.9 82.1 51.8 59.6 49.3 121.8 24.0 67.4 52.3 64.5 770.2 59.1 61.7 56.1 71.1 124.9 151.4 107.9 114.2 102.3 77.7 131.6 83.8 74.6 170.2 130.7 216.6 78.2 212.2 60.6 102.0 226.7 159.0 334.2 145.8 178.1 70.1 186.1 104.8 264.0 194.2 107.8 170.3 82.8 100.9 132.8 157.3 154.4 85.6 105.3 129.8 94.2 87.2 120.7 164.5 142.7 173.5 110.0 227.4 261.7 145.2 180.9 260.3 298.0 125.1 59.7 62.6 134.1 167.8 158.1 229.8 177.1 118.1 65.4 87.6 78.6 240.9 108.6 73.3 82.0 140.5 82.4 117.2 77.4 99.9 87.4 65.3 72.3 119.9 88.9 103.4 69.4 79.5 115.7 82.1 67.7 72.0 15.5 98.1 109.1 76.9 84.4 89.6 62.1 66.9 66.2 91.5 68.2 67.0 64.5 62.7 65.0 59.6 67.4 71.1 34.1 44.8 44.4 18.6 30.7 29.8 59.7 135.4 25.0 59.0 37.0 29.3 479.9 87.2 74.8 152.6 33.3 105.0 32.5 73.0 354.1 88.8 2.5 41.2 33.7 36.8 41.9 55.8 21.2 59.8 120.7 49.2 49.5 36.9 42.6 39.7 18.2 76.3 73.2 25.2 24.6 64.4 71.2 26.8 30.5 4.1 35.4 32.5 56.9 9.4 40.8 49.0 26.8 13.0 11.5 47.4 52.5 40.6 43.3 47.1 88.6 213.7 33.1 69.1 32.9 37.5 51.7 51.1 25.3 45.2 33.4 133.4 31.6 25.4 130.3 55.8 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA019950: AB_1855156, HPA062059: AB_2684671" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favorable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 6.0 2.6 3.6 1.8 4.6 1.5 3.6 6.9 5.2 2.0 7.7 3.8 5.4 2.6 3.4 3.7 3.4 2.0 1.8 3.6 4.3 9.2 8.6 3.4 2.6 6.2 4.6 7.4 4.5 6.1 3.0 4.0 6.8 3.8 4.1 5.0 3.6 2.6 2.5 2.1 3.2 2.1 3.5 2.0 3.0 3.8 5.7 2.5 9.3 4.1 3.0 2.1 2.2 4.3 9.8 11.7 7.1 14.1 18.7 9.6 8.9 5.0 19.2 11.3 17.0 23.9 6.7 13.5 6.9 6.9 10.8 12.1 20.8 11.3 10.9 3.2 10.5 6.8 5.9 15.9 10.1 8.8 11.5 7.4 8.3 16.1 16.6 12.3 4.9 14.9 13.3 9.5 10.3 6.3 17.1 6.2 8.4 6.5 14.7 16.7 9.9 21.4 6.0 10.3 14.3 8.0 15.9 6.5 6.0 5.5 8.7 4.3 4.6 7.0 9.2 4.2 7.5 16.6 16.9 13.4 9.5 6.9 7.0 1.1 0.2 1.2 3.8 0.1 3.1 1.0 1.8 3.2 0.8 2.1 2.6 3.0 0.7 4.2 0.1 0.5 0.6 1.3 3.6 4.6 6.9 5.2 3.6 4.3 6.2 4.6 6.8 3.5 5.7 4.3 2.5 9.6 22.9 8.1 3.1 5.2 6.4 1.3 6.2 9.6 5.8 4.2 5.1 8.6 3.1 9.2 14.6 12.8 3.3 13.3 7.9 3.4 0.2 3.5 3.2 3.3 3.6 0.8 8.8 2.9 2.2 4.1 3.1 4.3 6.3 14.4 7.1 20.5 2.4 5.0 7.6 4.2 2.0 1.3 0.4 2.4 3.1 1.2 3.6 3.7 0.4 8.1 7.2 4.5 4.3 3.4 6.6 4.5 4.5 8.9 7.4 9.9 1.2 6.7 0.0 5.9 2.7 12.6 5.7 8.0 2.4 3.6 3.4 4.0 5.5 6.5 PDXK "C21orf124, C21orf97, FLJ21324, FLJ31940, MGC15873, PKH, PNK, PRED79" ENSG00000160209 "Pyridoxal kinase" O00764 21 43719094-43762307 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 87.0" "Group enriched" "Detected in all" 4 "Early spermatids: 1717.4;Late spermatids: 4366.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030196, HPA030197, HPA030198, CAB033918" Enhanced Enhanced Nucleoplasm NA NA 830000 "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "CAB033918: AB_2162502, HPA030196: AB_10599735, HPA030197: AB_10601792, HPA030198: AB_10603570" "unprognostic (1.01e-1)" "unprognostic (1.99e-1)" "unprognostic (5.88e-2)" "unprognostic (1.87e-1)" "unprognostic (8.29e-2)" "unprognostic (4.31e-3)" "unprognostic (3.64e-3)" "unprognostic (1.32e-1)" "unprognostic (8.66e-2)" "unprognostic (9.34e-2)" "unprognostic (2.10e-1)" "unprognostic (3.54e-1)" "unprognostic (3.70e-2)" "unprognostic (1.31e-3)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.51e-3)" 25.6 21.8 79.4 7.6 62.2 12.9 18.4 23.9 87.0 14.3 17.5 17.1 14.1 12.3 10.2 19.7 14.0 7.0 15.5 62.5 51.7 50.4 21.5 20.9 7.0 48.8 59.7 19.1 21.3 17.8 37.3 7.8 54.7 17.2 9.4 10.0 22.7 10.6 6.7 13.9 19.7 6.9 34.4 12.5 16.6 23.9 70.5 10.2 19.1 5.4 9.3 10.9 12.6 57.6 43.4 51.9 8.1 15.5 19.4 27.3 9.9 15.2 23.8 14.5 12.1 42.5 65.7 14.4 15.7 21.9 20.0 31.9 15.8 43.4 9.5 16.2 13.4 14.7 60.9 31.7 38.1 14.0 20.6 38.9 40.7 15.3 16.9 23.6 6.9 6.3 26.2 31.9 13.8 29.1 2.0 24.9 22.3 41.9 19.7 16.7 4.8 40.4 62.9 51.9 7.8 9.3 63.3 57.7 23.2 3.3 19.0 19.4 12.5 10.5 20.3 14.2 14.4 19.3 9.8 8.4 43.2 39.9 10.3 0.6 2.4 0.1 0.8 2.2 1.5 0.6 0.8 0.9 1.3 1.7 0.8 0.6 0.6 0.9 4.3 0.6 0.7 1.4 79.4 62.2 23.9 87.0 62.5 51.7 48.8 59.7 54.7 34.4 70.5 57.6 15.8 80.1 66.6 44.1 37.7 28.4 142.4 72.2 27.3 46.3 74.8 53.5 48.0 34.3 73.2 101.2 22.9 42.9 23.6 97.6 180.0 146.4 1717.4 66.9 28.3 36.1 30.1 15.8 49.3 196.6 86.3 39.4 63.2 73.2 31.8 23.8 17.2 54.2 207.6 52.2 48.7 55.4 12.2 58.2 101.0 4366.5 50.1 118.7 42.7 61.8 38.4 14.9 20.6 16.6 13.5 223.4 36.4 54.2 146.4 184.7 108.4 95.7 71.1 43.3 6.6 17.0 35.0 678.1 30.4 60.7 28.4 124.1 27.3 22.1 57.5 239.8 PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Cell type enhanced" "Detected in many" "Early spermatids: 232.9;Excitatory neurons: 313.2;Oligodendrocyte precursor cells: 745.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 24.8;cerebral cortex: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.1;EFO-21: 4.5;SiHa: 11.6;SK-BR-3: 10.6;T-47d: 5.5" "Low region specificity" "Detected in all" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB020784: , HPA036503: AB_2675161, HPA036504: , HPA064387: AB_2685252, HPA076072: " "unprognostic (3.65e-2)" "unprognostic (4.06e-2)" "unprognostic (6.63e-2)" "unprognostic (5.42e-5)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (3.38e-2)" "unprognostic (2.45e-2)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-3)" "unprognostic (4.13e-2)" "unprognostic (6.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.79e-1)" 16.5 0.9 4.5 0.7 24.8 0.1 5.0 0.7 15.7 2.2 10.6 1.4 0.5 2.5 1.9 5.3 2.2 0.9 18.8 4.7 0.3 8.2 0.1 9.0 0.3 4.5 4.3 14.4 1.2 0.6 1.8 10.9 1.0 1.5 0.7 14.8 1.6 1.9 2.5 10.1 0.6 2.4 0.3 0.2 1.7 5.6 4.1 2.6 1.0 4.8 1.7 0.6 2.1 0.0 0.1 0.0 3.1 0.1 0.0 0.0 8.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 4.5 0.0 1.2 4.3 1.7 0.9 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 2.2 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 3.5 0.0 0.1 0.7 11.6 10.6 0.0 2.6 5.5 0.0 0.0 0.0 2.2 0.0 0.5 0.0 0.0 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 24.8 0.7 15.7 4.7 0.3 4.5 4.3 1.0 0.3 4.1 0.0 26.2 44.8 38.6 39.2 0.2 16.8 4.4 14.0 13.6 7.0 10.6 6.9 53.9 0.0 9.3 5.5 98.0 25.5 1.9 0.1 0.0 0.2 232.9 9.7 16.9 14.7 0.0 1.3 313.2 0.2 3.4 8.6 7.7 33.2 1.3 18.7 5.7 0.2 2.2 15.2 113.2 0.0 4.1 0.3 3.1 55.2 7.5 1.0 7.2 87.1 0.2 6.4 0.0 745.0 104.7 3.5 0.0 10.5 0.1 3.5 0.0 8.2 2.8 62.1 46.0 7.3 13.4 12.3 3.8 15.1 18.5 21.1 1.3 46.8 0.0 1.8 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 160.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 91.0;Proximal enterocytes: 49.5;Proximal tubular cells: 79.1" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 38.3;RPTEC TERT1: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" 25.4 5.4 2.7 2.9 3.1 7.1 10.2 3.8 2.9 4.5 6.0 8.7 26.0 3.3 4.1 3.1 8.1 9.7 2.4 2.7 2.8 33.9 160.2 6.4 3.9 3.2 3.1 4.1 4.8 7.2 3.2 1.0 3.3 5.0 7.5 2.2 5.6 3.4 6.8 4.2 20.1 3.2 2.6 3.0 3.9 0.5 3.0 3.4 16.1 5.2 3.8 2.3 2.3 3.7 6.0 6.6 2.6 0.1 15.7 5.7 3.1 1.4 3.3 3.7 6.3 7.6 17.1 0.1 11.9 3.5 9.2 1.4 7.5 8.7 6.5 9.5 7.7 7.8 3.6 38.3 15.7 2.0 5.1 5.0 6.1 3.9 5.5 5.6 3.8 4.6 3.3 8.6 8.2 4.4 2.4 2.2 4.8 0.1 4.9 5.3 5.0 0.9 35.9 1.0 3.6 5.2 3.6 7.4 15.6 6.2 8.6 6.5 0.0 2.4 2.5 6.0 4.3 9.8 8.9 3.1 5.3 2.8 5.6 1.2 4.2 1.5 6.5 1.6 7.7 4.3 8.8 7.5 1.5 5.7 9.2 6.1 4.5 9.9 2.3 0.2 16.6 4.1 2.7 3.1 3.8 2.9 2.7 2.8 3.2 3.1 3.3 2.6 3.0 3.7 4.3 6.4 13.6 6.5 7.0 3.7 4.7 4.0 3.4 10.8 2.4 2.9 3.7 35.8 3.4 29.5 14.6 3.9 5.9 11.5 13.7 13.2 0.1 10.1 2.7 3.9 7.2 9.4 15.4 3.8 7.3 5.0 7.7 6.3 1.3 2.0 6.8 91.0 9.6 3.3 18.4 8.0 6.1 4.7 3.7 0.3 5.6 5.5 10.6 8.4 27.4 10.1 9.2 8.5 10.6 5.0 17.7 8.2 5.9 2.0 49.5 79.1 13.1 6.4 0.0 6.6 4.4 0.1 1.6 4.9 2.8 1.6 11.4 1.9 14.6 2.7 PEX11A "MGC119947, MGC138534, PEX11-ALPHA" ENSG00000166821 "Peroxisomal biogenesis factor 11 alpha" O75192 15 89677764-89690783 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 38.7;Late spermatids: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (1.40e-1)" "unprognostic (6.17e-2)" "unprognostic (6.80e-3)" "unprognostic (2.82e-2)" "unprognostic (2.38e-1)" "unprognostic (3.24e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-2)" "unprognostic (5.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.32e-2)" 25.6 10.4 7.9 3.4 8.3 0.8 20.0 6.9 8.5 7.2 12.8 14.5 16.3 6.0 10.5 6.5 9.6 5.4 8.1 7.9 8.7 11.7 39.1 6.1 2.5 7.1 7.8 13.1 11.8 10.0 5.5 3.6 7.2 18.3 12.0 12.7 11.3 10.1 17.9 5.4 12.2 5.5 7.2 4.1 11.3 11.4 9.0 2.3 10.9 12.0 3.7 9.2 6.1 7.9 10.2 6.1 4.6 0.3 23.4 8.4 3.7 5.0 8.5 7.4 12.0 4.3 11.9 4.7 5.5 5.8 10.6 13.3 0.0 7.6 8.5 7.5 16.8 7.1 7.2 6.0 16.8 4.7 2.4 10.4 9.2 4.3 7.1 5.8 5.2 4.6 0.1 1.8 5.6 10.2 0.0 0.6 2.6 20.6 11.1 0.0 0.0 4.2 6.1 6.8 3.4 8.7 16.0 54.4 15.5 8.3 14.4 4.4 4.7 4.9 4.8 13.2 4.0 5.3 9.5 0.2 11.9 0.7 4.3 1.2 0.7 2.3 3.6 1.0 2.0 1.6 1.8 2.0 1.8 0.9 2.2 2.5 0.8 3.1 0.7 0.4 1.7 1.5 7.9 8.3 6.9 8.5 7.9 8.7 7.1 7.8 7.2 7.2 9.0 7.9 1.5 6.4 8.4 12.4 2.0 1.8 9.3 5.2 7.4 8.6 15.3 10.9 8.7 10.0 11.4 5.5 2.1 10.8 1.3 22.1 5.9 7.6 24.8 7.1 5.5 3.1 3.6 0.8 3.0 4.6 7.1 4.6 3.1 5.2 1.3 6.2 4.6 38.7 4.0 18.5 3.5 8.9 6.1 3.5 0.8 39.0 5.3 1.6 3.6 2.8 1.9 14.5 1.0 3.5 3.5 5.5 11.6 2.6 0.6 11.5 20.7 12.6 16.2 9.7 0.0 6.4 4.6 22.6 8.7 5.0 2.0 2.7 1.5 11.0 11.8 11.9 PEX19 "D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1" ENSG00000162735 "Peroxisomal biogenesis factor 19" P40855 1 160276807-160286348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044837, HPA051966" Supported Supported Peroxisomes NA NA 7900 "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Peroxisomes "HPA044837: AB_10962496, HPA051966: AB_2681677" "unprognostic (1.49e-2)" "unprognostic (2.26e-1)" "unprognostic (3.42e-1)" "unprognostic (4.80e-3)" "unprognostic (3.89e-2)" "unprognostic (3.88e-2)" "unprognostic (3.79e-1)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.53e-2)" "unprognostic (8.06e-2)" "unprognostic (1.00e-1)" "prognostic favorable (2.92e-5)" "unprognostic (3.46e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-2)" "unprognostic (1.24e-2)" 79.3 25.7 21.1 14.5 22.5 12.3 36.5 22.2 23.5 20.3 15.6 22.6 19.4 18.2 25.0 24.9 22.9 19.6 39.4 21.5 22.7 33.1 109.1 21.6 16.6 22.3 23.5 23.6 17.2 40.4 15.0 21.9 23.5 28.0 23.2 30.9 21.3 26.6 66.2 18.2 18.8 16.7 22.1 16.7 20.0 16.8 22.7 21.0 34.3 84.8 20.5 23.9 15.2 24.5 31.2 18.9 69.8 22.4 59.8 57.8 53.0 25.3 51.3 44.6 35.3 35.1 37.2 37.8 40.9 37.3 26.3 29.7 34.2 44.0 35.3 32.3 17.3 26.6 26.5 36.3 46.9 48.6 32.6 84.7 51.0 60.0 38.6 35.8 32.2 51.4 40.8 27.9 50.0 17.8 37.0 15.8 50.3 38.6 48.2 45.7 34.4 45.5 45.8 61.8 23.2 38.3 98.3 49.5 37.4 71.3 48.1 48.2 24.8 26.5 31.1 29.9 30.1 42.5 57.9 68.6 43.1 20.9 38.9 9.1 5.5 5.0 5.8 8.9 4.2 5.0 2.8 3.5 5.5 1.9 4.0 3.7 2.2 4.7 6.6 3.4 4.2 2.3 21.1 22.5 22.2 23.5 21.5 22.7 22.3 23.5 23.5 22.1 22.7 24.5 16.4 9.6 20.6 9.1 12.7 9.9 21.0 15.4 13.1 18.8 18.9 16.4 45.6 20.0 11.3 16.5 10.4 30.0 6.9 25.4 49.0 22.6 6.6 12.0 13.7 13.6 11.4 15.6 8.6 14.8 51.2 18.4 13.3 12.0 16.5 15.6 20.0 60.1 30.1 25.2 9.0 11.5 0.0 15.7 7.0 3.1 21.8 15.0 21.4 6.5 24.9 39.0 12.3 6.0 11.5 20.2 17.2 29.3 9.5 18.5 29.8 40.7 11.8 12.7 32.9 14.6 16.2 17.8 25.3 15.0 9.9 38.7 12.5 18.2 15.7 25.2 PFKFB1 PFRX ENSG00000158571 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1" P16118 X 54932961-54998534 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 28.3;liver: 50.2;skeletal muscle: 111.6;tongue: 40.8" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 15.9" "Cancer enriched" "Detected in some" 11 "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.5;Hep G2: 3.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.51e-1)" "unprognostic (2.39e-2)" "unprognostic (1.17e-2)" "unprognostic (4.38e-3)" "unprognostic (1.64e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (3.26e-3)" "unprognostic (2.88e-1)" "unprognostic (5.36e-3)" "unprognostic (5.06e-1)" "unprognostic (4.87e-2)" "unprognostic (1.16e-4)" "unprognostic (1.96e-3)" 28.3 0.5 0.4 0.1 0.5 0.4 9.2 0.3 0.5 0.1 0.1 0.4 0.1 0.1 0.6 1.1 0.1 0.3 0.3 0.4 0.4 1.1 50.2 0.2 0.5 0.5 0.4 0.0 1.2 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.7 0.2 111.6 0.8 0.5 0.1 0.4 0.3 0.4 0.4 0.4 0.4 1.0 40.8 0.6 0.2 0.2 0.5 0.2 0.1 0.2 0.4 8.5 0.1 0.6 0.0 0.1 0.1 0.0 0.5 0.1 0.4 0.1 0.0 0.4 0.3 0.1 0.2 0.3 0.3 0.7 0.2 0.1 3.2 0.0 0.0 0.3 0.1 0.4 0.0 0.2 0.0 0.0 0.8 0.1 1.4 0.1 0.5 0.4 0.2 0.2 0.2 0.2 0.3 0.1 0.1 0.0 0.2 0.2 0.1 0.3 1.0 0.1 0.7 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.7 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.5 0.4 0.4 0.5 0.4 0.4 0.4 0.4 0.5 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 15.9 0.1 0.0 1.5 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 334.6;skeletal muscle: 621.3" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Collecting duct cells: 195.0;Langerhans cells: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 296.2;RPTEC TERT1: 181.8;T-47d: 192.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: AB_2678717" "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 334.6 22.7 66.1 72.2 81.2 246.0 153.8 75.4 66.6 30.2 22.1 22.2 19.4 24.0 11.1 51.3 37.7 59.9 21.9 62.8 105.8 243.9 32.8 67.7 24.5 145.7 100.9 24.2 21.0 10.1 39.6 20.0 100.9 20.2 8.9 31.5 40.4 49.5 621.3 53.6 22.9 16.9 90.1 50.2 26.1 13.9 91.8 15.1 10.9 30.4 28.2 63.9 40.3 105.6 22.0 296.2 23.1 18.8 85.2 10.5 12.2 31.6 22.5 22.9 35.5 14.1 78.0 37.2 20.2 13.8 18.0 69.0 24.9 50.2 26.3 44.6 17.3 22.1 16.2 5.2 7.2 21.6 32.2 7.6 16.4 39.5 9.5 58.3 44.9 25.6 16.6 13.6 18.6 35.7 15.3 20.3 22.5 31.1 20.5 34.3 11.3 14.7 181.8 11.1 21.9 8.9 22.9 24.7 45.8 39.5 192.0 25.2 57.0 23.9 22.0 3.1 38.7 27.8 10.4 33.7 65.8 25.0 37.4 2.9 7.5 7.7 2.2 9.2 5.7 1.8 4.2 2.9 4.7 1.6 3.0 3.0 26.4 1.2 5.5 2.9 4.3 4.3 66.1 81.2 75.4 66.6 62.8 105.8 145.7 100.9 100.9 90.1 91.8 105.6 37.1 76.9 55.1 153.8 27.2 102.6 16.7 21.5 37.5 6.4 37.1 36.8 19.5 22.8 32.1 195.0 52.1 0.4 37.0 14.9 0.0 54.7 5.0 41.1 18.9 32.9 8.5 1.3 42.8 25.7 6.9 30.8 33.1 64.3 44.2 72.5 8.9 15.8 20.6 6.7 19.4 6.6 18.3 88.0 132.3 9.5 2.8 122.2 46.2 41.2 19.6 0.3 4.1 14.1 31.9 59.6 5.2 7.2 25.3 4.2 5.4 2.4 19.2 1.9 0.0 58.5 24.4 0.6 2.5 20.9 63.9 1.0 61.7 12.4 8.1 14.7 PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "monocytes: 214.9;Squamous epithelial cells: 496.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Cell line enhanced" "Detected in all" "A549: 1445.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" 115.8 51.0 49.5 59.8 49.2 400.2 89.0 52.9 49.3 75.9 52.5 52.9 91.6 23.1 41.9 572.4 30.0 94.2 34.3 47.4 54.3 53.2 81.3 88.5 38.1 57.0 54.6 35.7 32.0 52.7 43.8 47.4 55.4 30.4 46.3 49.1 133.7 22.9 34.7 50.0 70.7 35.0 49.7 110.4 61.4 68.3 59.2 53.6 71.8 28.2 73.8 61.8 126.9 52.0 191.5 1445.2 319.3 340.6 445.4 274.0 71.8 124.8 185.9 144.4 195.3 219.2 190.4 163.5 151.0 109.2 202.4 148.0 225.6 192.1 96.4 127.5 199.9 227.8 264.3 452.1 136.3 390.9 249.7 196.5 92.2 229.4 55.5 186.9 344.0 223.0 305.3 145.7 183.5 202.5 321.4 179.4 194.7 221.0 109.1 252.7 298.1 312.2 199.6 105.5 178.0 154.1 99.1 153.5 137.5 196.7 173.3 308.5 369.3 81.1 149.6 98.3 134.5 111.6 256.0 323.5 175.1 393.9 73.6 1060.2 321.0 1074.7 23.2 137.7 26.5 33.1 21.4 20.8 144.6 23.3 21.1 22.3 332.6 19.7 105.6 98.7 23.1 225.0 49.5 49.2 52.9 49.3 47.4 54.3 57.0 54.6 55.4 49.7 59.2 52.0 7.4 19.2 35.0 11.8 24.9 13.0 30.8 78.0 70.6 7.8 30.4 18.5 11.0 50.1 73.2 20.2 18.8 134.6 29.8 24.3 52.8 52.1 10.9 17.8 18.6 22.6 23.4 55.7 8.6 40.3 40.7 37.5 41.8 24.5 25.9 53.9 16.1 66.2 134.6 1.7 12.6 30.2 59.0 163.8 30.9 13.4 17.1 150.9 17.8 4.7 214.9 16.5 10.3 13.6 9.0 38.7 26.7 10.5 41.9 43.5 66.6 55.1 46.2 20.2 19.7 23.4 21.5 41.5 38.4 496.0 16.6 81.3 19.4 27.3 51.7 76.1 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1559.1;tongue: 788.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 238.4;Extravillous trophoblasts: 185.9;Hepatocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 21000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: AB_2679625" "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 113.7 70.8 31.6 20.7 34.7 21.5 57.4 34.3 38.4 33.9 53.1 58.9 60.8 22.9 19.2 49.3 17.0 30.3 178.9 31.4 34.0 52.2 279.8 42.6 14.7 44.7 34.1 51.0 112.2 65.3 31.8 26.9 32.7 46.6 49.9 22.6 41.8 49.7 1559.1 30.6 55.1 41.4 31.9 14.7 30.6 11.1 36.5 14.3 27.5 788.0 19.4 38.4 22.1 30.2 113.4 47.0 17.3 57.0 111.0 81.4 138.6 45.7 61.8 48.9 79.0 38.8 51.3 35.8 93.2 71.2 107.4 26.5 24.0 96.3 55.9 44.0 32.1 75.3 72.6 40.3 91.6 66.8 4.3 103.4 60.7 57.1 88.5 129.8 29.6 36.3 0.1 46.3 78.8 6.9 19.6 36.7 78.3 3.4 73.9 26.8 80.0 11.8 70.0 35.3 10.4 66.7 100.0 103.0 157.4 78.6 32.4 25.2 3.1 71.6 36.0 64.0 39.4 29.1 45.5 57.8 117.0 58.0 31.5 46.0 33.2 49.2 40.5 22.4 32.7 22.4 23.5 31.0 48.4 11.8 21.0 24.7 38.7 43.9 21.2 13.9 20.4 35.4 31.6 34.7 34.3 38.4 31.4 34.0 44.7 34.1 32.7 31.9 36.5 30.2 8.4 93.0 29.4 48.3 16.9 17.8 29.0 58.8 47.8 9.2 33.8 21.8 139.2 48.6 24.2 16.5 10.4 76.6 14.2 81.8 88.0 55.9 32.0 8.2 12.1 12.7 13.1 5.7 17.9 238.4 185.9 37.0 27.0 13.5 5.1 134.3 15.0 214.4 24.6 0.0 26.3 47.5 20.3 17.0 10.8 8.5 22.1 13.5 26.6 4.7 32.8 75.8 29.9 32.2 9.8 70.5 31.6 38.0 40.4 29.2 90.2 74.8 17.0 11.4 13.1 53.4 25.5 5.6 10.1 57.3 18.2 58.8 19.0 20.2 81.5 19.0 PHACTR2 "C6orf56, KIAA0680" ENSG00000112419 "Phosphatase and actin regulator 2" O75167 6 143536845-143831185 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 164.2;placenta: 83.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 82.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031719, HPA031720, HPA031725" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA031719: AB_10696055, HPA031720: AB_10670553, HPA031725: AB_10610279" "unprognostic (3.25e-3)" "unprognostic (1.07e-1)" "unprognostic (4.39e-2)" "unprognostic (5.25e-2)" "unprognostic (1.90e-2)" "unprognostic (8.38e-2)" "unprognostic (3.19e-2)" "unprognostic (9.92e-2)" "unprognostic (7.46e-2)" "unprognostic (3.61e-2)" "unprognostic (2.49e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.99e-4)" "unprognostic (3.60e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-2)" "unprognostic (1.17e-1)" 11.6 25.4 7.0 7.8 9.0 7.6 5.5 4.3 5.7 8.1 164.2 8.5 7.5 9.9 3.6 22.0 5.7 8.4 12.4 10.0 4.9 5.9 7.9 15.7 7.8 12.3 10.3 6.5 4.9 13.1 4.0 83.8 15.1 10.3 8.5 2.7 6.0 6.9 4.5 2.7 6.1 9.8 3.5 13.5 12.0 6.5 16.5 2.7 15.5 7.3 6.7 7.6 6.4 4.5 21.9 13.5 3.6 26.6 3.7 8.0 15.3 18.0 27.2 7.7 9.6 23.9 9.5 1.2 47.5 51.7 5.4 6.5 2.0 17.9 9.1 18.1 8.5 35.5 14.7 14.0 6.1 9.1 10.5 11.2 9.8 7.7 24.9 11.8 47.0 6.7 10.2 0.1 12.4 24.0 1.3 2.1 26.8 7.7 3.8 3.3 26.3 0.2 9.3 19.2 5.2 5.2 20.0 26.1 0.3 13.4 9.8 13.1 82.2 34.9 18.2 15.2 11.8 0.2 0.1 0.3 8.6 9.5 3.2 6.0 3.5 6.7 3.3 2.5 12.3 0.4 4.0 4.4 3.3 0.2 2.4 1.6 1.8 3.5 2.7 3.2 5.5 1.9 7.0 9.0 4.3 5.7 10.0 4.9 12.3 10.3 15.1 3.5 16.5 4.5 160.9 214.7 94.5 41.4 11.7 24.2 16.0 19.5 47.3 37.0 14.2 13.8 71.8 32.9 73.2 22.0 2.1 84.7 27.5 58.9 13.7 30.5 10.1 49.6 43.7 158.6 21.6 32.8 55.2 22.5 49.8 144.8 54.6 64.7 38.7 34.9 157.1 27.6 35.4 101.0 133.8 19.2 24.4 121.1 40.2 23.2 103.2 52.5 24.9 77.8 71.7 10.3 15.5 5.5 20.9 49.4 22.3 120.0 10.6 63.3 20.2 24.8 51.1 3.0 98.6 95.9 83.5 3.1 2.3 33.0 17.2 52.5 51.3 127.9 26.3 30.9 PHLDA3 TIH1 ENSG00000174307 "Pleckstrin homology like domain family A member 3" Q9Y5J5 1 201464278-201469237 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 269.3;Prostatic glandular cells: 188.7;Urothelial cells: 556.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 284.8;WM-115: 164.3" "Low region specificity" "Detected in all" HPA027601 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "HPA027601: AB_10601389" "unprognostic (1.51e-1)" "unprognostic (7.48e-2)" "unprognostic (5.65e-2)" "prognostic favorable (1.77e-4)" "unprognostic (8.55e-3)" "unprognostic (4.34e-3)" "unprognostic (5.55e-3)" "unprognostic (1.42e-1)" "unprognostic (2.16e-3)" "unprognostic (8.65e-2)" "unprognostic (8.78e-2)" "unprognostic (7.65e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (9.32e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (7.45e-2)" 155.6 30.0 34.9 8.4 50.6 0.3 119.3 51.2 41.9 56.8 21.3 139.4 4.1 52.9 11.6 89.4 40.8 15.3 40.9 31.7 39.4 18.2 8.1 41.6 2.5 73.4 50.3 23.5 23.4 10.7 28.4 8.9 51.3 64.8 5.5 3.0 39.3 26.8 75.9 68.3 29.0 17.8 45.2 10.4 35.1 8.9 52.1 10.1 31.5 11.6 4.9 75.5 68.4 69.2 52.4 60.8 11.1 33.5 50.6 47.7 284.8 75.6 57.3 18.2 21.0 4.0 39.5 0.1 3.1 37.6 15.7 90.0 1.0 61.0 3.6 0.0 22.4 0.0 26.2 47.6 57.4 0.0 1.0 66.7 90.6 29.4 25.8 53.5 26.3 4.5 0.0 0.1 36.7 37.5 8.0 0.8 19.1 0.0 3.8 2.5 51.9 0.0 16.9 115.1 0.7 11.7 26.5 0.8 62.7 42.5 25.0 3.6 39.4 42.2 69.6 36.1 16.2 1.4 0.2 0.1 102.4 0.1 164.3 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.2 0.0 0.1 0.6 0.0 34.9 50.6 51.2 41.9 31.7 39.4 73.4 50.3 51.3 45.2 52.1 69.2 83.3 9.6 9.1 8.8 0.9 78.1 269.3 48.8 93.9 5.2 29.8 42.4 6.2 2.8 30.7 49.7 0.0 84.9 1.8 2.2 11.7 42.0 36.8 42.7 15.2 22.2 5.3 2.7 5.7 18.9 24.4 43.3 7.1 31.8 0.0 11.2 10.4 1.4 18.1 0.0 8.3 2.1 10.2 0.6 28.5 136.5 26.8 7.9 32.0 1.0 18.2 105.4 1.0 4.5 37.1 71.4 2.9 41.8 2.1 188.7 1.2 8.5 22.3 5.2 0.0 38.0 55.8 0.8 4.0 92.1 102.0 37.5 5.7 46.5 3.6 556.5 PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 87.2;Late spermatids: 87.7;Oligodendrocytes: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.2;ASC TERT1: 105.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "Plasma membrane" "HPA037959: AB_10673651, HPA038448: AB_10697390" "unprognostic (7.81e-2)" "unprognostic (8.32e-3)" "unprognostic (1.13e-1)" "unprognostic (9.36e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.37e-3)" "unprognostic (1.22e-1)" "unprognostic (3.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.36e-6)" "unprognostic (7.09e-2)" "unprognostic (2.42e-2)" "unprognostic (3.69e-2)" "unprognostic (1.44e-1)" 52.6 8.1 39.2 11.5 79.7 0.5 38.9 42.5 66.0 39.1 3.8 23.8 9.2 38.4 2.6 9.1 30.2 21.6 33.0 42.3 49.2 15.8 3.2 26.8 4.6 64.3 64.6 31.9 22.2 4.5 8.8 24.6 56.0 16.7 6.4 1.6 11.1 15.8 13.3 15.1 15.3 18.6 33.4 12.5 14.3 12.0 75.3 3.1 20.3 13.6 2.3 21.9 22.9 133.7 4.8 7.5 28.9 14.2 105.2 105.9 10.1 21.9 26.6 12.7 7.4 11.2 31.8 0.0 40.2 44.3 17.2 18.6 6.6 44.8 2.0 0.7 4.2 8.6 5.7 5.5 27.2 0.0 15.8 55.8 9.6 17.8 12.5 28.3 36.6 0.7 7.5 0.3 16.7 3.4 0.1 0.5 10.2 0.4 3.8 1.1 7.5 0.7 12.5 6.8 6.5 14.5 55.8 4.7 15.6 11.3 20.1 2.7 45.4 25.9 22.9 13.2 18.3 0.2 0.0 0.1 7.5 1.5 29.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 39.2 79.7 42.5 66.0 42.3 49.2 64.3 64.6 56.0 33.4 75.3 133.7 34.4 6.4 13.7 53.2 1.6 18.4 9.2 13.7 14.2 4.0 7.2 19.6 5.6 1.5 6.3 31.3 0.0 1.0 2.5 34.2 0.0 9.4 78.3 11.6 87.2 32.1 8.4 0.0 4.1 4.4 1.5 54.9 11.7 8.6 1.3 25.6 26.4 0.9 5.9 3.3 8.3 20.4 0.0 2.5 34.4 87.7 67.1 8.2 12.4 23.4 2.2 7.6 0.0 67.3 244.5 24.3 29.8 44.4 0.7 4.2 10.7 7.8 0.5 2.3 39.5 42.9 53.8 21.9 10.1 1.9 9.1 1.5 5.4 11.0 16.8 2.4 PHYH "PAHX, PHYH1, RD" ENSG00000107537 "Phytanoyl-CoA 2-hydroxylase" O14832 10 13277796-13302412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 667.8;skeletal muscle: 483.6;tongue: 412.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 258.6;Proximal tubular cells: 414.6" "Cancer enhanced" "Detected in all" "liver cancer: 78.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007598, HPA011796" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA007598: AB_1855334, HPA011796: AB_1855335" "unprognostic (5.78e-2)" "unprognostic (3.83e-1)" "unprognostic (6.98e-2)" "unprognostic (3.62e-2)" "unprognostic (5.52e-2)" "unprognostic (1.61e-3)" "unprognostic (1.16e-1)" "unprognostic (1.95e-2)" "unprognostic (7.09e-2)" "unprognostic (6.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.24e-1)" "prognostic favorable (7.28e-12)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.19e-1)" 57.9 66.5 22.9 9.5 23.7 8.2 32.2 23.5 28.3 28.8 31.7 46.5 58.7 22.1 16.7 22.9 16.7 28.2 126.5 21.7 24.1 191.4 667.8 17.3 7.5 21.6 24.4 36.8 48.2 56.7 20.9 19.3 22.8 22.5 37.2 28.2 33.7 25.4 483.6 17.5 55.8 23.2 22.7 12.8 44.2 15.1 26.0 5.6 56.0 412.7 5.4 27.0 14.8 23.6 17.2 35.2 15.6 22.5 110.7 69.9 12.4 17.2 23.9 19.4 19.1 9.1 30.3 0.9 12.9 29.0 47.0 7.8 20.5 20.2 11.8 41.4 10.7 14.9 9.3 36.6 54.8 2.5 26.8 50.3 28.9 21.0 8.4 22.7 18.7 16.8 8.4 32.2 45.5 16.3 9.2 12.1 14.4 49.4 12.6 15.7 24.1 5.8 40.6 21.9 5.3 16.8 64.8 1.4 32.9 12.5 64.8 44.2 6.4 29.5 10.6 36.4 11.8 36.6 26.3 3.3 38.3 18.9 11.6 16.3 18.7 8.2 8.0 14.2 17.6 11.0 9.9 10.4 15.8 5.6 12.5 12.7 0.8 4.4 11.2 14.4 10.5 12.3 22.9 23.7 23.5 28.3 21.7 24.1 21.6 24.4 22.8 22.7 26.0 23.6 53.6 12.8 19.2 8.5 14.5 11.9 27.6 19.1 6.2 47.0 22.6 24.5 258.6 77.2 19.7 35.0 22.9 137.8 20.5 72.9 144.8 40.6 33.1 18.5 29.0 29.7 31.8 15.2 7.1 19.6 34.3 41.3 41.8 26.8 30.4 28.3 25.0 145.5 55.4 21.9 5.6 57.4 46.8 21.0 22.0 45.4 25.4 25.3 17.8 4.7 10.3 69.3 7.2 2.5 2.4 16.7 46.0 37.6 15.1 11.9 141.9 414.6 19.6 41.8 19.7 30.2 37.5 12.5 1.6 7.3 13.4 83.9 25.2 103.3 46.9 18.1 PIK3R5 "p101, P101-PI3K" ENSG00000141506 "Phosphoinositide-3-kinase regulatory subunit 5" Q8WYR1 17 8878911-8965712 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 87.4" "Cell type enhanced" "Detected in some" "dendritic cells: 29.9;Kupffer cells: 35.7;Langerhans cells: 40.5;Macrophages: 36.8;Microglial cells: 79.6;NK-cells: 32.0;Plasma cells: 24.7;T-cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 39.2;HMC-1: 5.7;JURKAT: 13.7;U-937: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044505, HPA052247, HPA052412" Uncertain Supported "Centriolar satellite,Cytosol" No NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Centriolar satellite" "HPA044505: AB_2678964, HPA052247: AB_2681772, HPA052412: AB_2681823" "unprognostic (2.81e-1)" "unprognostic (1.31e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (9.89e-3)" "unprognostic (1.42e-1)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (7.95e-2)" "unprognostic (1.33e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" "unprognostic (6.89e-2)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.24e-1)" 6.5 3.6 1.4 19.7 1.3 87.4 2.7 1.3 7.5 2.1 1.6 3.3 3.3 1.4 0.8 2.5 3.0 6.6 1.8 1.3 1.7 1.4 2.9 14.1 13.7 4.0 2.7 0.8 1.3 0.8 0.8 3.1 3.6 1.5 2.6 0.0 2.1 1.0 0.7 1.5 9.5 3.9 2.8 22.4 3.6 2.2 6.8 12.3 1.7 0.9 8.9 6.5 1.4 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.4 1.5 0.0 0.0 0.0 0.5 5.7 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.3 1.5 2.5 0.6 0.0 0.0 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 9.5 16.1 5.7 18.1 14.3 11.8 4.3 10.1 15.6 11.5 5.7 7.5 12.0 34.4 8.6 19.0 9.0 13.2 16.2 1.4 1.3 1.3 7.5 1.3 1.7 4.0 2.7 3.6 2.8 6.8 5.4 0.2 0.0 6.1 0.7 11.7 1.0 0.0 0.0 0.0 0.0 0.2 0.3 2.1 1.5 0.0 0.0 0.0 0.1 29.9 0.0 0.0 0.1 4.5 0.1 0.1 0.7 0.0 4.0 0.3 0.0 0.3 0.5 1.5 0.1 5.1 0.0 1.4 0.4 18.3 0.0 0.5 0.0 0.0 35.7 40.5 12.2 0.3 36.8 1.8 79.6 19.8 0.0 32.0 1.0 0.3 0.0 0.0 0.0 24.7 0.1 0.0 0.2 0.0 0.0 0.0 0.4 1.4 0.6 0.4 0.1 0.9 0.4 25.7 0.0 0.0 0.0 PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697261 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1255.9;Inhibitory neurons: 330.9;Oligodendrocyte precursor cells: 281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" 25.7 8.9 27.2 5.6 30.1 3.8 18.6 23.5 26.9 8.7 13.2 7.6 1.5 7.8 3.8 9.8 10.9 3.8 13.3 22.7 31.2 21.8 9.8 15.1 8.8 38.4 41.0 15.2 23.1 1.8 13.7 6.0 28.2 11.9 2.2 15.0 14.1 4.4 5.4 4.9 8.7 3.5 28.7 9.4 12.6 2.5 42.7 8.4 9.0 5.0 7.4 12.0 9.2 20.1 4.2 1.0 4.5 6.8 2.8 5.1 3.9 6.0 2.9 0.8 0.4 0.0 6.4 4.6 1.4 3.6 1.7 2.0 6.7 6.0 1.1 9.3 3.0 0.7 7.6 3.4 0.7 1.4 9.8 3.6 2.2 0.9 2.5 0.5 3.2 6.5 0.3 16.9 2.3 7.0 10.9 2.8 6.6 1.8 7.7 15.2 0.9 4.2 9.7 5.4 4.7 13.0 1.7 3.3 4.1 4.8 3.0 4.7 3.7 1.8 1.0 2.4 2.9 13.2 6.2 3.7 14.4 4.6 1.6 0.7 1.4 10.3 11.1 2.6 5.7 0.5 6.9 9.2 0.9 1.3 8.2 8.3 1.7 5.2 4.1 0.1 2.8 4.1 27.2 30.1 23.5 26.9 22.7 31.2 38.4 41.0 28.2 28.7 42.7 20.1 102.6 9.6 1.1 1255.9 9.6 5.4 55.6 4.6 8.0 15.2 7.7 4.1 6.9 21.5 4.6 0.0 2.1 7.9 84.0 5.8 21.5 43.3 0.2 13.7 5.7 59.8 6.0 4.0 88.4 49.1 13.6 18.9 8.2 30.9 5.1 7.7 21.4 10.1 13.8 74.0 330.9 1.3 4.1 21.4 22.3 1.4 5.0 17.7 10.6 103.0 20.2 34.6 84.5 281.5 9.7 38.7 4.4 14.7 28.0 32.9 0.1 21.2 3.4 21.8 26.3 66.5 25.7 0.4 3.8 9.0 4.3 3.4 75.7 2.7 3.8 54.3 PITX3 ASMD ENSG00000107859 "Paired like homeodomain 3" O75364 10 102230186-102241512 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.5;skeletal muscle: 16.5;tongue: 6.0" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 22.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "midbrain: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "RH-30: 30.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 9.1" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.13e-2)" "unprognostic (4.07e-1)" "unprognostic (5.15e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (6.04e-5)" "unprognostic (6.30e-3)" "unprognostic (2.02e-1)" "unprognostic (6.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.73e-2)" "unprognostic (1.76e-2)" "unprognostic (6.76e-3)" "unprognostic (4.13e-2)" 1.2 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.1 0.2 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 16.5 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.0 5.5 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 22.1 0.3 1.4 1.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 PJA1 "FLJ11830, RNF70" ENSG00000181191 "Praja ring finger ubiquitin ligase 1" Q8NG27 X 69160851-69165521 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 160.0" "Cell type enhanced" "Detected in many" "Early spermatids: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 99.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000595 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA000595: AB_1079826" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (4.03e-2)" "unprognostic (2.58e-3)" "unprognostic (5.44e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-2)" "unprognostic (3.82e-3)" "unprognostic (1.84e-2)" "unprognostic (6.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.44e-5)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-1)" 22.9 14.5 46.8 8.7 50.5 3.6 19.4 37.2 78.0 19.9 33.0 15.4 6.4 16.4 160.0 12.3 16.0 11.1 15.0 47.1 48.9 19.2 9.4 13.8 10.0 38.9 41.7 25.8 14.5 38.7 28.1 17.3 40.6 15.3 7.6 17.6 10.6 32.4 7.9 14.6 11.1 16.0 40.1 13.3 14.0 26.4 49.0 10.0 22.7 8.8 12.1 17.4 15.1 43.5 27.3 19.6 62.9 43.7 21.3 22.5 18.7 17.8 22.0 16.7 22.3 17.1 25.8 4.4 26.7 28.1 39.2 24.0 99.0 34.9 21.2 20.2 33.0 8.1 16.0 10.9 25.7 4.9 14.4 23.1 23.6 28.6 17.0 15.8 19.0 13.2 7.8 3.0 16.9 14.1 2.1 8.4 43.4 23.1 32.0 20.0 28.2 6.9 23.4 22.6 46.4 30.7 28.6 4.9 22.2 50.1 7.7 7.0 17.8 13.9 22.6 41.7 8.3 0.0 0.2 9.1 15.3 13.1 19.4 6.6 6.8 2.1 29.6 9.2 34.3 16.4 26.1 27.5 7.3 22.8 26.5 31.3 2.3 30.0 6.5 8.9 17.5 19.4 46.8 50.5 37.2 78.0 47.1 48.9 38.9 41.7 40.6 40.1 49.0 43.5 4.7 16.0 4.8 2.9 9.7 41.0 19.4 30.8 23.9 16.8 5.0 6.2 7.1 4.3 14.8 3.7 8.4 35.6 5.9 1.0 15.6 24.9 74.7 3.9 10.4 6.6 5.4 10.8 8.1 11.7 15.3 18.2 7.1 5.8 4.5 27.9 6.8 1.7 7.0 5.0 8.3 3.6 6.1 2.9 9.9 32.7 27.1 5.7 5.4 2.8 2.9 30.6 14.4 5.0 3.7 18.0 1.7 19.5 7.7 17.0 0.5 6.5 4.4 6.1 6.6 9.4 16.3 1.4 1.5 11.2 29.5 20.8 11.2 27.0 2.6 22.5 PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 318.7;brain: 394.8" "Cell type enhanced" "Detected in some" "Adipocytes: 80.5;Cardiomyocytes: 151.9;Cytotrophoblasts: 137.4;Extravillous trophoblasts: 365.5;Hofbauer cells: 71.0;Syncytiotrophoblasts: 290.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 187.8" "Group enriched" "Detected in all" 6 "dendritic cells: 187.8;T-cells: 55.0" "Cell line enhanced" "Detected in many" "A549: 135.1;ASC diff: 148.2;CAPAN-2: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" 318.7 36.2 208.5 10.2 287.0 3.1 166.8 234.7 261.6 13.3 142.8 32.8 8.7 17.6 26.6 13.2 33.0 29.1 103.0 197.7 215.3 65.0 76.5 37.6 11.6 283.0 250.7 73.4 32.4 28.6 33.4 40.3 279.8 16.4 7.6 26.6 28.9 29.9 108.9 10.7 21.8 15.8 241.2 15.9 31.9 54.7 237.1 7.1 41.2 118.7 4.4 26.7 9.6 394.8 87.7 135.1 3.7 0.2 148.2 25.1 24.1 3.2 26.9 22.3 11.2 30.8 247.1 0.0 55.3 6.9 72.4 4.4 127.4 6.8 16.9 108.0 5.0 1.3 33.3 5.4 87.8 0.0 1.3 15.2 0.7 55.4 2.2 88.1 35.4 0.0 1.6 9.6 24.0 15.3 0.2 0.6 10.8 55.0 43.0 0.0 0.0 8.7 71.2 12.3 1.7 9.7 18.0 51.5 28.7 54.6 111.6 4.5 52.2 10.0 0.7 34.0 7.7 39.6 28.0 0.3 40.1 0.0 1.0 0.1 21.1 0.1 55.0 9.1 30.3 7.4 12.1 40.5 6.4 1.2 3.9 30.0 1.3 21.0 0.6 187.8 9.3 27.2 208.5 287.0 234.7 261.6 197.7 215.3 283.0 250.7 279.8 241.2 237.1 394.8 80.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.9 0.0 0.0 0.0 0.0 137.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 365.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 290.6 2.0 0.0 0.0 0.0 PLAAT5 "HRASLS5, HRLP5, iNAT, PLAAT-5" ENSG00000168004 "Phospholipase A and acyltransferase 5" Q96KN8 11 63461404-63491194 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 16.5;pancreas: 13.6;testis: 53.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Syncytiotrophoblasts: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 3.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 64 "basophil: 5.4;eosinophil: 16.4" "Lineage enriched" "Detected in single" 97 "granulocytes: 16.4" "Group enriched" "Detected in some" 5 "HAP1: 11.4;NB-4: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042493 Uncertain "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA042493: AB_10797499" "unprognostic (3.16e-1)" "unprognostic (3.45e-2)" "unprognostic (2.83e-3)" "unprognostic (4.24e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (7.11e-3)" "unprognostic (2.14e-1)" "unprognostic (6.66e-2)" "unprognostic (9.46e-2)" "unprognostic (8.89e-3)" "unprognostic (3.15e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-5)" "unprognostic (1.52e-1)" "unprognostic (1.21e-2)" "unprognostic (2.57e-3)" "unprognostic (4.50e-4)" 16.5 0.2 1.2 0.3 0.9 0.1 3.3 0.7 0.8 0.1 0.0 0.7 0.2 0.5 0.2 0.8 0.9 0.6 0.6 1.0 1.3 0.1 0.0 0.6 0.1 1.5 0.5 0.6 13.6 0.0 0.0 0.0 1.0 0.4 0.2 0.5 0.8 1.3 0.1 0.2 0.3 1.4 1.1 0.1 0.5 53.4 0.8 0.0 0.1 0.1 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.7 0.8 1.0 1.3 1.5 0.5 1.0 1.1 0.8 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 PLEK P47 ENSG00000115956 Pleckstrin P08567 2 68365282-68397453 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 604.8" "Cell type enhanced" "Detected in many" "dendritic cells: 310.7;Hofbauer cells: 220.3;Kupffer cells: 213.9;Langerhans cells: 456.5;Macrophages: 412.7;monocytes: 178.3;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 552.9;HL-60: 126.7;HMC-1: 202.5;NB-4: 187.5;THP-1: 215.6;U-266/84: 147.8;U-698: 147.1;U-937: 342.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031838, HPA057341" Enhanced Approved Nucleoli NA NA 380000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "HPA031838: AB_10602146, HPA057341: AB_2732609" "unprognostic (2.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.52e-3)" "unprognostic (3.52e-1)" "unprognostic (3.08e-2)" "unprognostic (4.67e-2)" "unprognostic (3.40e-2)" "unprognostic (4.00e-2)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (3.57e-1)" "unprognostic (4.42e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" 36.4 9.8 4.9 99.4 7.1 604.8 8.2 6.0 10.0 6.9 6.5 13.2 10.4 4.7 3.3 6.0 7.2 21.0 5.4 4.9 5.3 4.0 27.5 35.6 129.9 8.0 6.1 2.6 2.7 2.7 1.9 29.2 8.1 4.2 18.8 0.5 5.7 3.1 1.7 3.4 13.0 22.2 7.3 93.5 11.3 3.2 7.2 33.7 3.8 5.2 118.2 52.3 2.5 12.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 93.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 552.9 0.0 0.0 0.0 126.7 202.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 58.9 0.0 0.0 0.2 187.5 0.0 0.0 0.0 1.5 0.1 27.3 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.0 215.6 0.1 0.0 0.4 0.1 0.5 7.9 147.8 147.1 0.2 342.5 0.1 231.9 297.5 429.2 298.5 351.6 157.6 157.7 52.2 218.7 229.6 103.6 14.5 161.8 573.9 249.5 390.8 474.8 5.7 606.9 4.9 7.1 6.0 10.0 4.9 5.3 8.0 6.1 8.1 7.3 7.2 12.3 3.4 19.2 24.6 0.0 77.0 6.5 0.3 0.0 0.0 0.0 1.4 3.7 2.3 1.5 15.5 1.8 0.0 1.2 310.7 0.0 0.0 0.2 1.5 0.2 0.3 6.3 0.0 21.9 0.6 0.6 1.8 10.2 1.5 0.3 62.0 0.0 5.7 1.5 220.3 0.0 0.2 0.0 0.0 213.9 456.5 5.1 0.6 412.7 17.8 20.6 178.3 0.0 355.3 0.0 0.1 0.1 0.1 0.4 48.4 0.0 0.0 0.7 13.1 0.1 13.1 1.1 1.8 0.8 0.9 0.6 6.7 2.6 78.3 0.4 0.0 0.3 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PLEKHG6 "FLJ10665, MYOGEF" ENSG00000008323 "Pleckstrin homology and RhoGEF domain containing G6" Q3KR16 12 6310436-6328506 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.9;intestine: 43.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 117.9;Extravillous trophoblasts: 56.2;Paneth cells: 67.5;Proximal enterocytes: 62.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 153.2;CACO-2: 50.1;CAPAN-2: 27.3;OE19: 48.0;RT4: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041459, HPA058230" Uncertain Supported "Cell Junctions,Centrosome" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Centrosome "HPA041459: AB_10794518, HPA058230: AB_2683645" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" "unprognostic (1.44e-1)" "unprognostic (8.03e-3)" "unprognostic (5.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.20e-2)" "unprognostic (1.22e-1)" "unprognostic (3.13e-1)" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (6.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (4.18e-2)" "unprognostic (5.73e-2)" 15.1 0.3 1.3 4.3 1.2 2.7 12.8 1.5 2.0 7.5 2.1 31.0 36.5 0.5 0.5 33.9 1.0 5.0 0.3 1.0 0.9 2.7 4.5 1.3 0.6 1.4 1.4 0.2 5.6 7.9 5.2 8.5 1.0 3.0 17.9 0.2 13.3 1.3 0.4 12.1 43.4 1.1 0.7 0.5 11.0 0.8 1.3 0.7 3.9 0.2 2.5 15.7 15.0 1.5 0.7 6.0 0.8 0.1 2.9 0.2 153.2 0.3 0.0 0.4 0.3 50.1 27.3 0.3 0.4 0.0 0.2 13.0 0.0 0.4 0.2 0.1 0.1 0.2 1.5 10.2 0.5 0.5 0.4 0.0 0.7 0.2 0.0 0.5 0.1 0.2 0.4 0.3 0.0 7.9 0.0 0.7 12.7 48.0 1.0 0.2 0.2 0.3 0.1 53.2 0.3 0.2 1.2 23.1 0.3 10.9 7.5 0.0 1.2 0.2 0.5 0.6 0.2 0.0 0.1 0.1 0.8 0.7 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 1.3 1.2 1.5 2.0 1.0 0.9 1.4 1.4 1.0 0.7 1.3 1.5 0.6 0.0 0.0 0.0 0.2 5.0 7.0 2.8 20.5 0.0 4.6 2.9 0.4 8.6 2.5 1.8 0.0 17.6 0.4 117.9 0.0 12.1 1.4 2.9 1.1 0.8 8.4 0.0 0.2 1.8 56.2 1.5 16.3 4.2 0.0 0.5 0.4 2.3 2.7 0.0 0.2 19.3 0.0 0.0 0.7 2.0 2.5 0.3 0.0 0.0 0.2 0.8 2.1 0.0 0.1 2.2 67.5 0.7 0.2 8.4 62.6 0.8 3.0 0.1 0.0 4.7 3.1 0.2 0.5 14.2 7.0 23.9 0.3 0.0 27.9 21.6 PLIN1 PLIN ENSG00000166819 "Perilipin 1" O60240 15 89664367-89679427 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "adipose tissue: 956.3;breast: 463.0" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 59.0" "Group enriched" "Detected in many" 5 "breast cancer: 8.4;liver cancer: 2.3;pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 171 "ASC diff: 208.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024299, CAB033821, CAB037333" Enhanced Uncertain Peroxisomes NA NA 22000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Peroxisomes "CAB033821: AB_2252681, CAB037333: , HPA024299: AB_1855467" "unprognostic (4.62e-2)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-1)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (9.89e-3)" "unprognostic (3.54e-1)" "unprognostic (7.01e-2)" "unprognostic (2.13e-2)" "unprognostic (8.00e-3)" "unprognostic (2.28e-3)" "unprognostic (2.62e-6)" "unprognostic (5.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "unprognostic (4.85e-2)" 956.3 11.3 12.0 3.5 14.8 0.3 463.0 7.4 10.6 1.4 5.3 9.3 0.5 0.7 0.4 1.3 1.4 6.6 10.4 10.0 10.3 2.7 40.8 0.7 1.7 6.9 11.5 2.1 6.1 0.2 1.3 0.2 7.8 2.6 3.7 0.6 20.8 0.6 9.5 16.0 13.9 1.5 6.6 1.0 5.5 13.2 10.6 2.3 5.3 17.3 0.1 7.9 3.1 8.2 0.0 0.2 0.2 0.0 208.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.7 0.5 0.1 0.7 0.2 0.0 0.2 0.6 0.7 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.3 1.2 0.1 0.5 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.4 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 14.8 7.4 10.6 10.0 10.3 6.9 11.5 7.8 6.6 10.6 8.2 2.6 0.0 0.0 4.2 0.2 0.1 0.3 0.1 0.0 0.3 0.7 3.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 7.5 0.1 0.2 0.2 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.2 0.0 0.1 1.1 59.0 0.0 0.0 0.3 0.3 0.0 1.0 0.3 7.5 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.2 1.3 0.0 0.0 0.6 0.3 0.1 0.1 0.1 0.0 1.3 1.3 4.8 0.2 0.0 0.4 0.0 0.1 0.1 0.5 0.9 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 202.0;skeletal muscle: 149.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.1;Astrocytes: 53.8;Cardiomyocytes: 39.8;Hepatic stellate cells: 42.1;Hepatocytes: 140.5" "Cancer enhanced" "Detected in many" "liver cancer: 9.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.9" "Cell line enhanced" "Detected in some" "AN3-CA: 2.3;BEWO: 3.2;RT4: 3.1;SH-SY5Y: 2.8;T-47d: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Lipid droplets" "HPA077050: " "prognostic favorable (7.68e-4)" "unprognostic (1.01e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-2)" "unprognostic (6.06e-3)" "prognostic favorable (2.81e-4)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (1.97e-4)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "prognostic favorable (2.16e-4)" 41.9 6.4 10.8 3.5 11.2 5.2 29.3 6.9 9.6 7.5 12.8 5.4 1.5 2.7 3.9 3.4 12.6 2.0 62.7 8.5 8.1 30.1 202.0 9.3 0.5 8.4 9.2 90.8 112.2 1.5 18.9 0.2 6.9 17.6 0.6 0.9 61.0 3.9 149.2 8.0 5.3 0.5 6.8 8.2 58.9 3.3 9.4 0.4 9.8 24.7 1.0 11.2 2.7 6.4 0.2 0.1 0.5 2.3 1.7 0.1 3.2 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.8 1.1 0.4 0.3 0.4 0.4 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.1 0.6 0.1 0.4 0.4 0.3 0.3 0.1 0.1 2.1 0.2 3.1 0.3 2.8 0.2 0.4 0.0 0.2 6.3 0.4 0.3 0.3 0.3 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.1 1.9 0.4 0.8 0.3 0.3 0.2 0.3 0.2 0.2 0.1 0.4 0.3 0.3 13.9 0.6 0.3 0.3 0.1 0.1 10.8 11.2 6.9 9.6 8.5 8.1 8.4 9.2 6.9 6.8 9.4 6.4 6.0 9.6 47.1 53.8 1.6 0.5 18.4 2.3 4.0 1.2 9.2 1.9 39.8 35.8 11.5 1.8 0.0 0.4 0.1 11.9 9.8 8.7 1.5 20.8 1.4 7.4 0.0 2.7 1.1 12.3 0.5 1.3 16.3 5.1 3.8 18.7 42.1 140.5 0.5 0.0 1.8 6.9 4.1 6.9 0.5 0.3 0.3 2.5 0.0 5.6 0.1 8.1 0.0 11.1 2.0 4.8 1.3 2.6 0.5 6.6 0.5 11.1 10.4 1.2 13.1 25.8 1.8 6.2 6.6 0.5 1.0 1.4 1.1 20.5 8.8 11.5 PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821955 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 9.8;brain: 21.1;fallopian tube: 11.1" "Cell type enriched" "Detected in some" 7 "Endometrial ciliated cells: 37.2" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NB-4: 61.8;THP-1: 128.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: AB_2681787, HPA057034: AB_2683316" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" 0.0 0.0 16.8 0.2 14.1 9.8 2.2 0.0 21.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 11.1 0.1 0.1 14.2 11.5 0.0 0.0 2.3 0.1 4.1 8.2 0.3 0.0 0.2 0.4 0.0 1.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 2.3 0.2 0.1 3.2 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.5 12.2 0.0 0.0 0.0 6.9 0.2 0.1 0.0 0.0 0.7 0.1 0.1 8.4 0.1 0.1 0.3 2.3 0.0 0.0 0.0 5.2 0.0 1.6 0.0 0.5 4.4 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 12.0 0.3 0.0 1.1 0.0 61.8 9.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 15.5 0.3 0.0 0.0 6.3 5.4 128.9 0.1 0.2 0.2 0.3 0.1 0.2 0.5 0.2 0.0 10.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 14.1 0.0 21.1 14.2 11.5 4.1 8.2 1.5 2.3 13.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 3.7 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 37.2 0.6 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.4 0.0 1.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 0.1 5.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123332-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.8;brain: 29.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 235.3;Inhibitory neurons: 261.3" "Cancer enhanced" "Detected in many" "glioma: 3.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 29.1;hippocampal formation: 26.0" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cell line enhanced" "Detected in some" "ASC diff: 25.2;HMC-1: 17.1;hTERT-RPE1: 22.1;RH-30: 18.5;TIME: 57.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029919: AB_10671093, HPA052141: AB_2681745, HPA075592: AB_2732297" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.61e-6)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.19e-1)" "unprognostic (7.99e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-5)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (5.90e-2)" "unprognostic (1.42e-3)" 13.8 2.4 4.2 1.6 5.6 0.3 7.6 0.1 29.1 8.4 0.0 1.5 0.4 1.5 0.2 3.8 2.0 1.9 3.9 26.0 1.3 0.7 0.3 1.2 1.0 2.3 0.1 3.6 0.4 0.1 1.0 3.5 1.8 0.5 0.7 4.8 0.4 0.9 0.7 2.2 0.8 2.6 0.9 1.5 1.6 1.1 1.6 0.2 1.5 3.1 0.3 1.0 0.7 4.4 0.0 0.1 0.2 0.0 25.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 17.1 0.2 0.0 0.1 0.0 22.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 18.5 2.0 0.0 0.0 0.4 9.6 0.0 0.0 0.0 0.2 0.0 0.0 57.6 5.7 0.2 1.3 0.5 0.0 0.0 0.0 5.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.6 0.0 0.0 4.2 5.6 0.1 29.1 26.0 1.3 2.3 0.1 1.8 0.9 1.6 4.4 2.5 0.0 0.0 5.2 0.6 0.6 0.2 0.0 0.0 22.4 2.2 0.1 10.9 0.0 0.0 12.9 16.7 0.1 17.4 0.0 0.0 0.0 14.0 2.1 3.0 2.7 1.2 0.0 235.3 0.0 0.1 7.4 1.1 5.0 1.3 1.6 5.0 0.2 0.1 0.0 261.3 0.1 0.0 0.0 1.1 9.8 14.0 0.7 7.2 10.3 0.0 11.3 2.1 51.8 3.7 0.8 0.0 7.2 0.7 0.1 0.0 0.5 0.0 1.5 0.0 0.7 1.1 0.2 0.3 0.1 1.3 0.0 1.7 0.4 0.1 0.4 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 47.0 51.7 49.0 12.0 50.4 26.2 39.0 47.0 65.0 34.4 41.2 33.6 37.7 26.9 19.2 73.7 34.7 18.8 26.5 49.5 52.1 59.4 64.2 33.8 17.5 46.9 47.2 48.1 45.0 15.4 19.5 14.2 51.2 26.5 20.3 13.6 23.3 20.2 16.2 33.2 33.8 19.9 47.8 13.7 65.7 32.6 49.8 14.3 13.8 11.4 16.8 31.7 28.0 49.7 16.0 29.0 19.6 42.5 54.3 84.0 23.0 61.7 69.8 56.0 61.0 23.0 15.3 14.9 20.3 74.4 40.0 23.4 25.8 40.0 31.1 31.2 38.6 3.8 34.8 49.2 85.8 22.6 23.8 70.4 38.2 58.3 24.2 61.9 9.3 23.8 16.9 51.9 76.5 42.0 17.1 32.5 6.2 75.1 38.2 13.1 20.7 30.7 24.0 17.1 5.8 11.2 50.5 18.1 75.2 15.2 20.3 24.4 7.5 63.2 34.3 59.4 32.8 33.2 34.0 24.3 70.3 18.8 38.7 21.0 22.0 44.8 27.7 18.5 22.3 17.8 27.6 22.8 23.2 20.5 29.4 21.1 28.8 13.4 22.9 9.2 49.4 18.8 49.0 50.4 47.0 65.0 49.5 52.1 46.9 47.2 51.2 47.8 49.8 49.7 7.8 35.3 106.4 16.3 15.0 14.8 10.2 22.5 20.5 16.7 22.8 29.3 12.4 82.9 25.8 35.0 6.2 57.1 10.0 104.8 107.6 31.8 17.1 77.7 34.2 6.9 48.7 19.3 14.9 11.0 91.1 33.3 36.2 51.4 3.8 60.9 8.9 83.5 34.5 28.6 10.9 58.1 14.2 14.4 13.5 15.3 28.0 16.3 44.4 3.7 21.9 67.1 16.5 4.0 7.1 10.8 117.0 30.5 17.7 8.5 176.1 138.5 34.8 22.6 39.5 18.9 36.9 72.6 10.9 23.1 14.1 65.3 21.0 37.9 55.3 8.2 PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;fallopian tube: 18.2;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 61.5;dendritic cells: 12.6;Inhibitory neurons: 23.3;Melanocytes: 14.2;Plasma cells: 80.4" "Cancer enriched" "Detected in many" 8 "ovarian cancer: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 231.2;naive B-cell: 260.3;plasmacytoid DC: 194.0" "Group enriched" "Detected in many" 20 "B-cells: 260.3;dendritic cells: 194.0" "Group enriched" "Detected in some" 6 "Daudi: 38.3;Karpas-707: 29.2;RPMI-8226: 11.2;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced "Secreted to blood" NA NA 12300 "Cluster 19: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA044507: AB_10795043, HPA056724: AB_2683216" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.94e-6)" "unprognostic (3.71e-2)" "unprognostic (5.16e-5)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (7.81e-4)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" "unprognostic (7.57e-9)" "unprognostic (2.19e-2)" "unprognostic (5.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-1)" 0.2 0.8 5.4 9.9 5.1 2.7 0.6 1.3 10.8 0.2 1.3 2.9 4.3 0.1 0.0 0.6 18.2 1.1 0.1 2.9 9.9 0.7 0.2 1.0 25.1 10.4 6.3 0.4 0.0 0.0 0.0 0.0 9.9 0.2 1.5 0.0 1.6 0.1 0.0 0.1 5.8 0.5 14.3 14.4 3.2 0.6 4.3 2.7 0.4 0.0 23.6 3.7 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 4.0 4.4 23.0 0.1 0.1 0.0 0.2 11.5 2.3 0.2 7.7 0.1 231.2 0.2 0.1 1.1 260.3 0.1 0.1 1.3 1.2 3.2 194.0 0.5 11.1 5.4 5.1 1.3 10.8 2.9 9.9 10.4 6.3 9.9 14.3 4.3 3.0 0.1 0.0 1.9 1.3 61.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.4 0.4 0.2 0.0 23.3 0.1 0.0 0.0 0.3 2.8 0.3 1.7 14.2 1.0 3.0 0.0 1.0 0.0 0.9 0.1 0.0 0.0 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 1.1 0.0 0.3 0.5 PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818914-825573 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 508.1;breast: 361.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "HPA055173: AB_2682725, HPA062602: AB_2684804, HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" 508.1 75.3 11.9 9.2 14.0 43.1 361.4 13.6 18.8 42.2 13.4 58.1 19.3 49.2 2.8 39.9 50.8 9.5 171.3 11.9 14.0 61.9 58.4 57.3 8.1 17.5 11.8 50.5 75.4 9.6 46.3 8.4 16.8 46.6 4.8 1.3 81.1 16.7 194.6 71.8 74.7 6.4 12.6 51.2 71.3 32.1 12.8 10.9 55.3 64.3 4.1 64.8 44.5 15.3 33.9 26.0 5.3 14.0 194.4 17.2 34.1 35.3 28.1 21.6 19.1 22.3 33.3 19.9 20.4 26.7 13.6 30.0 8.1 14.6 6.6 25.9 71.5 27.6 11.2 36.3 63.3 19.2 33.4 33.9 18.7 14.5 16.7 22.3 17.7 14.5 23.8 19.9 19.5 20.0 25.8 42.3 15.2 34.3 55.1 24.6 11.5 45.7 21.4 7.7 19.6 26.0 65.3 55.0 21.9 3.4 23.7 22.0 32.5 19.3 15.0 12.7 16.3 75.2 49.8 16.7 48.4 27.0 13.8 11.5 9.5 22.1 3.7 6.1 3.6 4.7 4.8 5.4 6.1 4.1 5.4 4.4 8.2 4.0 7.1 7.0 4.2 4.7 11.9 14.0 13.6 18.8 11.9 14.0 17.5 11.8 16.8 12.6 12.8 15.3 78.1 6.4 11.8 12.7 63.5 44.2 69.2 34.2 42.1 14.0 79.5 67.1 45.5 61.5 65.2 51.5 8.4 70.2 50.8 151.8 33.2 65.1 22.1 58.0 31.8 51.8 51.5 52.6 8.9 65.3 32.0 37.4 204.4 114.3 11.4 42.2 100.6 50.6 29.2 11.8 7.5 96.1 20.3 27.6 29.0 6.2 48.4 46.6 42.7 16.9 29.6 32.2 21.6 5.5 13.8 142.2 170.7 39.1 92.0 78.5 166.8 45.0 31.3 9.0 65.7 64.4 50.7 33.5 23.9 53.7 41.2 169.4 53.3 182.2 43.6 195.5 POLN ENSG00000130997 "DNA polymerase nu" Q7Z5Q5 4 2071918-2242121 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.4;testis: 2.6" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Excitatory neurons: 77.7;Inhibitory neurons: 42.7;Oligodendrocyte precursor cells: 22.1;Oligodendrocytes: 26.8;Spermatocytes: 23.4" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035939, HPA035940" Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA035939: AB_2674875, HPA035940: AB_2674876" "unprognostic (8.52e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.45e-2)" "unprognostic (3.46e-1)" "unprognostic (2.70e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-1)" "unprognostic (2.02e-3)" "unprognostic (1.25e-1)" "unprognostic (1.49e-3)" "unprognostic (9.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" 2.4 0.6 0.3 0.0 0.4 0.0 1.0 0.2 0.5 0.3 0.0 0.3 0.1 0.3 0.7 0.1 0.4 0.3 0.3 0.3 0.0 0.4 0.4 0.2 0.2 0.0 0.0 0.2 0.4 0.1 0.4 0.1 0.0 0.6 0.0 0.2 0.5 0.2 0.4 0.3 0.3 0.1 0.0 0.3 0.3 2.6 0.1 0.1 0.3 0.1 0.1 0.2 0.2 0.4 0.0 0.6 0.0 0.3 1.7 0.5 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.2 0.7 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 2.4 0.0 0.0 32.3 1.0 0.9 1.0 0.6 0.6 4.2 3.0 1.5 3.6 1.5 1.7 0.0 0.0 0.2 0.6 0.2 3.9 0.4 8.3 4.2 2.0 1.9 4.8 0.8 77.7 1.0 0.3 2.0 1.5 2.1 0.0 5.5 3.3 1.1 0.7 3.3 42.7 0.0 2.0 1.3 1.0 14.1 4.4 1.3 0.0 15.0 0.7 2.5 1.0 22.1 26.8 0.5 1.1 3.8 1.5 1.0 0.3 0.8 1.9 3.8 0.0 2.9 1.1 23.4 10.4 0.5 1.6 0.0 1.8 4.1 0.3 1.3 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 44.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 99.4;Hepatocytes: 144.5;Proximal enterocytes: 93.2;Rod photoreceptor cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 10.3;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;granulocytes: 10.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB075701: , HPA058901: AB_2683849, HPA067049: AB_2685770" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favorable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 7.9 6.3 9.6 4.5 12.7 6.6 3.8 9.5 6.9 4.1 23.5 11.8 18.4 3.8 3.6 7.7 4.1 4.4 26.3 7.7 8.8 22.4 33.2 4.0 3.4 11.0 11.2 11.2 8.2 7.4 2.6 4.3 10.0 6.2 9.1 18.2 7.8 5.7 26.2 7.7 18.4 4.3 8.6 4.4 6.1 1.3 11.7 3.7 7.0 44.6 3.9 5.1 4.0 10.5 7.8 1.9 2.4 8.4 13.0 8.3 5.3 6.7 13.2 7.0 7.2 3.8 3.7 2.8 3.3 15.6 6.5 3.5 7.1 8.7 6.3 8.1 8.9 8.7 4.8 8.0 8.1 6.0 14.3 6.6 6.9 5.2 11.8 6.0 1.5 6.3 3.2 6.4 6.6 2.0 6.8 2.2 0.3 6.5 1.9 8.0 8.6 3.6 4.7 4.6 2.4 7.0 2.6 2.4 8.0 3.2 2.7 4.6 2.6 7.3 7.7 6.7 2.9 6.3 4.0 1.2 11.4 6.6 2.3 1.4 0.8 10.3 1.0 1.0 0.8 0.8 0.5 0.5 0.6 1.0 0.6 0.4 0.7 0.7 0.7 3.1 1.4 0.2 9.6 12.7 9.5 6.9 7.7 8.8 11.0 11.2 10.0 8.6 11.7 10.5 15.0 3.2 13.6 49.6 8.0 23.3 15.0 7.8 9.1 15.0 14.3 11.4 99.4 22.8 8.9 7.3 62.6 8.0 18.4 58.8 9.8 10.3 0.6 9.4 26.4 15.5 19.9 32.0 1.4 16.6 6.7 16.0 14.8 18.4 5.1 19.1 22.5 144.5 8.8 5.0 13.8 31.4 0.0 24.8 10.2 1.1 19.6 10.4 3.6 10.3 12.2 16.0 8.2 19.6 27.2 13.0 24.5 30.1 10.6 19.1 93.2 40.8 5.0 148.0 6.6 31.0 15.8 0.7 1.7 19.3 34.2 3.0 9.6 14.6 37.9 19.9 PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 259.7;skeletal muscle: 831.6;tongue: 271.1" "Cell type enriched" "Detected in many" 4 "Distal tubular cells: 1348.0" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.8;NTERA-2: 29.4;RPTEC TERT1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007811, HPA041542" Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "CAB007811: AB_598171, HPA041542: AB_2677542" "unprognostic (6.39e-3)" "unprognostic (2.61e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (2.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.71e-3)" "unprognostic (1.76e-3)" "unprognostic (2.88e-3)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (8.49e-3)" "unprognostic (7.49e-2)" 241.3 2.6 37.1 1.1 73.6 0.3 169.8 26.1 45.7 1.6 20.4 29.6 3.0 2.2 0.7 10.3 3.8 1.5 110.9 38.9 36.9 259.7 138.1 1.0 0.5 29.0 32.0 7.7 14.2 20.8 1.8 0.0 26.0 7.9 1.8 14.6 9.7 3.2 831.6 7.6 13.2 3.3 25.5 0.5 27.8 2.2 31.6 0.2 2.6 271.1 0.5 5.4 1.5 34.1 0.0 0.0 3.9 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 5.4 0.0 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 0.0 0.2 32.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 73.6 26.1 45.7 38.9 36.9 29.0 32.0 26.0 25.5 31.6 34.1 7.9 0.0 0.0 3.3 3.4 0.1 0.0 0.0 0.0 2.2 23.7 40.6 300.7 5.7 0.0 18.4 0.0 0.0 0.5 0.0 1348.0 3.5 1.6 10.4 0.5 4.6 2.4 2.7 3.1 0.4 0.1 24.5 0.0 13.8 0.0 21.0 6.4 218.4 0.6 112.7 1.8 2.1 0.0 3.8 0.0 1.9 1.2 1.6 0.0 0.0 0.0 3.7 0.0 0.0 0.5 2.5 0.1 1.2 0.0 0.3 0.5 156.8 0.0 2.8 0.0 19.2 21.6 0.2 5.9 0.0 0.3 0.0 0.9 4.2 2.0 0.2 PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.6" "Cell type enhanced" "Detected in all" "Late spermatids: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA051066: AB_2681333" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (3.93e-2)" "unprognostic (8.54e-2)" "unprognostic (9.08e-3)" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-3)" "unprognostic (9.99e-3)" "unprognostic (3.56e-2)" "unprognostic (2.96e-1)" "unprognostic (4.89e-1)" "unprognostic (1.93e-1)" "unprognostic (9.23e-2)" 22.8 35.9 46.0 9.8 48.1 8.7 19.3 48.6 50.6 15.1 54.1 29.0 25.2 12.6 16.3 25.8 11.3 9.8 101.4 45.8 46.9 27.0 71.5 12.7 9.2 47.6 47.3 11.0 41.6 21.2 23.1 8.2 47.4 19.3 21.4 15.5 29.1 14.7 126.6 20.6 22.1 14.8 46.7 23.6 27.1 31.3 49.0 11.0 17.9 107.1 9.9 23.1 16.3 46.4 21.7 16.6 16.2 31.3 49.3 19.2 22.6 37.8 15.1 32.5 18.7 46.6 20.6 23.3 20.2 38.0 29.3 19.5 25.8 22.7 23.0 36.2 28.2 36.7 21.4 35.2 15.3 20.3 33.7 25.0 13.5 29.2 15.4 9.4 30.5 39.0 32.4 46.1 37.8 41.9 51.7 34.0 5.2 93.7 74.2 31.0 68.6 71.8 18.6 19.0 34.5 12.3 18.1 42.5 15.7 17.3 22.5 15.7 18.9 37.6 16.6 32.9 31.8 52.2 43.9 22.3 24.0 39.6 15.7 15.6 35.0 35.4 24.8 84.3 20.1 17.5 23.8 23.6 36.3 21.8 22.3 19.5 5.0 39.2 105.3 73.3 31.1 48.2 46.0 48.1 48.6 50.6 45.8 46.9 47.6 47.3 47.4 46.7 49.0 46.4 21.7 9.6 4.6 10.1 11.0 15.6 11.3 34.5 4.6 15.2 23.3 23.9 62.6 15.7 20.0 14.7 8.4 25.7 25.4 44.7 72.4 23.3 57.3 12.1 9.3 17.7 32.3 4.2 6.9 46.9 47.2 20.4 13.7 6.0 28.6 4.8 30.7 63.0 49.1 11.8 6.9 47.7 44.7 25.5 14.0 144.3 16.8 19.3 16.0 1.9 7.2 31.4 21.6 6.0 7.0 23.2 31.2 16.1 29.2 10.7 101.4 65.2 15.8 28.3 32.9 19.1 19.1 61.5 21.1 30.1 24.0 13.5 9.7 27.2 50.2 15.4 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477330-173488815 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1315.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 340.7 157.5 169.5 68.3 181.3 100.1 211.2 197.6 210.1 112.3 164.8 189.1 46.4 108.8 206.3 127.9 149.8 71.9 261.8 184.1 196.6 184.4 482.5 116.7 72.2 181.0 198.3 115.5 114.4 217.5 67.4 70.7 187.5 152.1 221.6 53.9 85.6 99.0 563.5 106.6 59.8 160.2 175.8 70.7 135.2 119.1 176.7 70.7 106.0 382.4 79.0 99.5 109.8 185.5 420.3 127.7 204.7 230.9 778.5 372.7 169.5 843.9 284.3 342.7 241.8 243.9 276.4 272.4 256.4 694.2 120.4 239.8 272.0 259.9 279.0 234.0 243.6 179.5 200.0 277.7 425.7 191.3 56.1 301.0 262.6 181.3 256.6 210.8 339.5 106.7 405.4 52.8 392.9 86.3 131.7 249.1 456.2 219.8 760.5 154.5 236.6 277.0 518.1 95.4 94.9 173.4 285.0 334.0 199.2 296.3 283.8 262.9 228.2 132.5 149.9 201.8 229.5 76.4 123.2 220.7 159.4 162.3 124.3 36.2 42.5 24.8 29.8 39.8 32.8 32.6 29.8 38.4 53.5 24.4 39.8 47.9 25.2 25.7 36.5 79.7 36.1 58.1 169.5 181.3 197.6 210.1 184.1 196.6 181.0 198.3 187.5 175.8 176.7 185.5 278.1 176.3 170.8 127.3 127.4 235.4 404.1 382.8 209.5 31.9 186.1 250.7 528.6 301.7 228.6 277.7 29.2 714.3 158.6 1315.9 860.8 178.6 237.5 206.9 226.8 191.8 142.1 449.5 13.8 202.3 939.1 307.0 111.6 200.0 348.6 216.6 214.2 1120.2 345.0 45.4 13.2 257.4 205.4 164.3 161.0 667.5 340.5 227.1 183.2 17.8 212.9 462.5 83.4 12.5 15.4 147.2 663.4 416.8 176.4 427.1 264.4 827.3 209.1 52.0 184.1 185.7 253.8 123.5 76.8 305.9 264.1 963.5 157.7 512.5 303.6 308.9 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044705-107161811 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 135.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 110.2;Excitatory neurons: 146.3;Granulosa cells: 712.1;Theca cells: 271.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 70.7;Daudi: 99.8;K-562: 61.4;U-698: 254.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008421, HPA063879" Enhanced Uncertain Mitochondria NA NA 570000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008421: AB_1855421, HPA063879: " "unprognostic (3.18e-1)" "unprognostic (2.48e-2)" "prognostic favorable (6.38e-4)" "unprognostic (1.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.43e-3)" "unprognostic (2.76e-1)" "unprognostic (8.14e-3)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.50e-1)" "unprognostic (5.12e-3)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.74e-4)" "unprognostic (7.15e-2)" 135.8 44.9 10.7 4.8 12.1 14.2 51.3 5.7 17.5 8.0 5.3 11.1 3.6 6.9 4.4 11.2 7.0 4.9 15.5 13.2 9.5 8.8 2.5 7.6 3.8 6.2 10.2 26.4 8.7 6.5 11.4 15.1 8.3 9.2 6.9 7.5 9.9 4.4 1.5 3.7 11.5 5.1 6.9 16.7 9.1 13.6 7.8 2.6 3.5 6.1 4.0 20.3 6.2 10.1 0.1 1.5 9.1 70.7 36.8 0.0 0.1 3.6 11.5 3.0 2.7 0.0 0.2 99.8 0.8 2.3 8.6 0.1 7.1 0.0 5.5 2.8 7.9 33.3 0.1 0.0 10.3 0.6 4.5 0.5 0.0 0.3 0.0 3.1 42.9 5.4 61.4 2.9 0.1 7.5 14.0 0.4 17.3 0.0 2.8 4.0 0.2 0.0 0.1 0.1 11.6 16.7 5.4 1.2 3.9 22.9 2.1 7.0 24.4 3.5 9.2 0.0 7.1 2.1 0.1 254.8 2.5 17.5 33.9 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.6 10.7 12.1 5.7 17.5 13.2 9.5 6.2 10.2 8.3 6.9 7.8 10.1 39.6 3.2 1.5 9.8 1.9 2.4 1.6 2.1 0.6 33.5 27.9 10.5 35.9 12.8 5.1 7.3 10.4 0.1 3.7 1.7 0.0 2.5 7.9 1.8 16.2 17.4 0.0 110.2 146.3 0.0 0.6 17.5 3.6 0.9 4.5 712.1 19.2 0.0 1.6 5.0 71.9 1.9 4.1 19.6 26.4 8.5 29.8 64.1 17.8 15.9 17.0 6.4 3.1 60.8 10.9 0.1 2.1 53.0 2.0 3.5 0.0 0.8 5.4 11.9 19.7 5.4 57.7 2.5 6.5 0.7 2.4 0.0 3.7 271.7 2.7 4.6 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 57.0;granulocytes: 52.9;monocytes: 73.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 267.7;THP-1: 194.0" "Group enriched" "Detected in all" 5 "basal ganglia: 121.4;thalamus: 334.6" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 30000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 46.1 59.7 10.4 45.4 11.1 90.3 28.9 4.4 11.7 25.9 7.3 43.5 54.8 9.1 39.1 32.7 42.3 32.8 19.6 12.8 11.0 25.6 8.8 44.3 46.8 9.9 8.5 13.6 33.2 20.7 8.2 20.5 7.5 39.3 41.5 2.2 25.9 31.9 6.8 34.0 55.7 16.2 9.5 54.2 65.1 20.8 9.0 16.3 41.8 9.2 62.1 44.2 23.2 12.3 33.5 14.4 5.2 8.7 35.9 21.6 46.2 20.4 25.7 24.5 23.7 34.4 31.9 86.5 8.3 45.6 42.9 14.5 34.1 49.8 20.6 75.2 23.6 50.1 18.3 32.0 23.6 64.8 103.4 17.1 35.8 25.6 23.2 21.8 22.4 9.3 9.7 11.8 36.1 85.0 7.0 81.0 13.0 51.5 23.0 7.6 13.6 20.6 25.5 72.8 8.3 6.5 15.4 267.7 39.6 24.0 22.6 194.0 31.5 11.7 14.4 15.4 19.2 18.1 33.6 45.9 27.6 116.4 22.6 51.8 73.7 50.1 3.6 71.3 2.2 6.2 2.1 2.5 57.0 8.2 2.2 2.0 52.9 6.9 47.7 16.3 2.6 24.1 10.4 11.1 4.4 11.7 12.8 11.0 9.9 8.5 7.5 9.5 9.0 12.3 4.3 3.2 23.5 2.0 25.7 29.2 26.3 8.0 23.9 0.3 11.8 4.3 6.4 14.3 16.1 14.7 0.0 3.1 24.7 61.8 3.9 8.9 34.5 18.5 4.4 2.7 26.5 5.2 3.4 10.7 16.0 6.7 54.0 17.8 5.7 8.9 3.3 2.3 44.8 1.7 4.2 37.1 4.1 47.4 43.0 75.6 9.0 41.5 10.6 20.6 44.9 2.0 8.2 1.0 0.5 13.2 55.4 6.8 25.8 19.7 64.5 13.1 16.5 0.2 6.6 6.5 12.1 23.1 3.7 23.9 27.8 8.8 10.0 10.4 23.0 34.6 PRR18 MGC35308 ENSG00000176381 "Proline rich 18" Q8N4B5 6 166305300-166308448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 127.0" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 27.3" "Group enriched" "Detected in some" 5 "glioma: 3.1;liver cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 4.3;SH-SY5Y: 2.5" "Low region specificity" "Detected in all" HPA077250 Enhanced NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA077250: AB_2732336" "unprognostic (2.91e-1)" "unprognostic (7.18e-2)" "unprognostic (1.76e-1)" "unprognostic (2.39e-2)" "unprognostic (1.44e-1)" "unprognostic (9.65e-2)" "unprognostic (5.60e-3)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.44e-3)" "unprognostic (4.79e-3)" "unprognostic (2.43e-1)" "unprognostic (3.35e-3)" "unprognostic (9.49e-2)" "unprognostic (9.58e-2)" "unprognostic (1.07e-1)" 0.3 0.0 36.1 0.0 90.6 0.0 0.1 38.8 63.8 0.1 10.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 34.3 37.2 0.2 3.3 0.2 0.0 54.5 61.1 0.0 0.2 1.2 0.9 0.0 42.6 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 32.8 0.0 0.1 0.0 60.2 0.0 0.1 0.0 0.0 0.0 0.0 127.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 2.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.1 90.6 38.8 63.8 34.3 37.2 54.5 61.1 42.6 32.8 60.2 127.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.6 2.8 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 27.3 0.1 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" 8.6 3.7 12.3 2.1 24.9 0.2 5.2 21.6 19.7 4.4 4.7 4.0 2.9 4.3 1.5 4.1 2.6 8.8 6.4 12.9 15.9 10.5 7.9 5.5 1.7 26.7 21.3 4.2 1.6 1.2 1.4 8.1 25.3 3.4 4.1 1.5 2.9 7.8 15.9 2.2 3.0 5.4 18.4 2.9 2.4 1.5 18.4 1.5 8.3 7.8 1.0 5.6 3.8 39.4 32.3 7.2 5.6 5.6 18.7 15.4 2.4 14.1 17.6 4.7 8.2 17.1 20.2 0.0 21.8 10.4 8.9 10.7 15.6 10.0 8.3 0.1 5.2 5.2 7.7 5.7 22.6 0.0 7.2 23.2 8.1 9.1 7.7 9.4 24.8 0.0 2.6 0.1 16.5 2.4 0.1 0.1 6.8 5.1 13.4 0.0 13.1 0.0 79.2 1.7 0.0 0.1 9.7 15.6 6.1 15.3 0.1 3.5 17.6 7.5 4.2 14.2 4.1 0.0 0.1 0.0 7.3 0.0 7.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.3 24.9 21.6 19.7 12.9 15.9 26.7 21.3 25.3 18.4 18.4 39.4 29.7 6.4 4.2 15.7 0.0 11.3 4.8 7.6 5.2 2.2 5.3 5.3 8.1 15.7 2.7 33.1 0.0 7.0 0.2 7.6 7.9 6.8 0.7 3.3 12.9 18.4 3.0 0.0 23.3 3.1 14.9 9.6 4.6 9.2 1.3 3.9 17.9 16.3 4.8 18.5 10.8 5.7 14.2 4.1 5.3 0.4 4.7 1.4 3.6 31.9 0.8 2.2 0.0 12.5 229.8 18.7 7.5 2.6 0.0 9.1 4.3 9.4 2.9 0.5 6.6 8.3 8.4 2.5 4.2 5.2 6.3 10.4 0.4 3.5 4.8 8.1 PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361685 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 16.3;bone marrow: 57.7" "Group enriched" "Detected in some" 7 "Bipolar cells: 4.8;Horizontal cells: 10.1;Inhibitory neurons: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 225.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" 16.3 1.3 3.2 0.4 2.7 57.7 8.5 3.2 2.9 2.5 0.7 1.3 0.1 0.5 0.0 2.7 1.1 0.7 1.5 2.0 6.3 0.1 0.4 0.9 0.1 4.7 4.8 1.1 0.3 0.3 0.2 0.0 4.0 0.4 0.2 1.0 1.1 0.8 4.5 2.3 1.2 0.4 3.6 2.1 2.1 0.4 5.1 0.6 0.5 4.5 0.0 0.5 3.0 2.1 0.0 0.1 0.3 0.5 1.3 0.1 3.8 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.2 8.8 0.1 1.3 0.0 0.0 0.1 0.0 0.0 12.8 0.0 0.0 0.0 1.0 2.6 46.6 1.2 0.0 0.1 12.9 0.6 1.0 0.0 0.1 0.5 225.3 0.4 0.2 0.3 1.5 0.1 6.1 0.0 0.0 1.0 0.5 0.1 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.7 3.2 2.9 2.0 6.3 4.7 4.8 4.0 3.6 5.1 2.1 0.4 0.0 0.0 1.0 0.0 0.6 0.1 0.2 0.6 4.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.2 10.1 12.6 0.0 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.8 1.2 0.3 0.3 0.1 0.0 0.0 0.1 PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 405.6" "Group enriched" "Detected in some" 7 "Adipocytes: 161.4;Cardiomyocytes: 161.5;Hofbauer cells: 75.1;Smooth muscle cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 166.0" "Lineage enriched" "Detected in all" 11 "dendritic cells: 166.0" "Cell line enhanced" "Detected in many" "ASC diff: 947.9;HaCaT: 276.4;HUVEC TERT2: 436.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" 405.6 25.1 112.4 15.9 110.4 3.6 210.2 97.4 119.8 92.0 122.6 51.8 84.0 52.5 212.8 83.9 30.9 30.8 76.3 121.8 104.3 110.9 197.3 20.9 18.0 108.2 111.3 30.7 66.0 69.0 59.1 45.2 108.5 70.4 43.2 42.9 50.6 44.3 49.7 81.1 59.8 19.9 103.1 12.3 24.8 51.5 131.1 34.7 55.1 75.8 26.9 71.4 51.9 101.5 26.0 62.9 105.3 0.4 947.9 0.1 7.2 4.0 22.0 2.0 0.5 60.1 76.3 16.6 82.1 0.3 47.1 276.4 9.5 10.9 0.5 1.1 17.6 32.5 23.8 89.0 91.9 0.3 9.0 71.1 20.2 6.7 0.3 250.1 436.7 95.1 26.9 0.6 0.0 89.6 41.9 4.7 51.2 39.1 0.3 117.5 48.5 0.8 223.1 106.2 107.6 76.6 11.0 147.7 168.4 78.9 66.2 46.2 119.1 0.6 1.0 0.5 0.6 9.3 22.0 0.4 66.0 0.6 7.6 1.3 3.5 11.6 6.6 0.8 5.1 15.8 3.7 5.5 3.3 11.1 13.4 13.9 2.2 6.2 0.2 166.0 0.2 4.8 112.4 110.4 97.4 119.8 121.8 104.3 108.2 111.3 108.5 103.1 131.1 101.5 161.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.5 0.0 0.0 0.0 0.0 13.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 7.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.0 PSMD8 "HIP6, HYPF, Nin1p, p31, Rpn12, S14" ENSG00000099341 "Proteasome 26S subunit, non-ATPase 8" P48556 19 38374550-38383824 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 708.9" "Cell type enhanced" "Detected in all" "Late spermatids: 1164.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006702, CAB021101" Supported Approved "Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nuclear speckles" "CAB021101: AB_10061018, HPA006702: AB_1079710" "unprognostic (9.50e-2)" "unprognostic (7.02e-2)" "unprognostic (1.70e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.59e-1)" "unprognostic (5.54e-3)" "unprognostic (1.94e-3)" "unprognostic (5.03e-2)" "unprognostic (2.85e-2)" "unprognostic (1.73e-2)" "unprognostic (4.61e-1)" "unprognostic (8.79e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.28e-1)" "unprognostic (2.08e-2)" "unprognostic (2.58e-3)" "unprognostic (4.84e-2)" 224.8 130.8 102.3 78.0 109.6 118.8 184.9 104.1 114.8 109.6 97.6 111.8 98.1 115.8 119.4 156.6 104.0 69.2 361.8 114.4 117.5 122.4 143.0 114.9 90.8 109.2 104.3 82.1 117.3 150.2 111.1 101.1 121.9 107.1 98.9 60.6 118.8 84.5 708.9 178.4 106.4 105.2 105.4 99.4 117.6 145.8 112.6 120.3 91.2 361.1 109.9 106.3 111.0 112.6 337.3 522.7 202.2 231.9 322.0 256.9 105.9 238.7 322.9 358.9 372.3 362.0 196.3 234.7 242.8 320.0 220.1 114.1 341.7 296.8 321.6 389.8 225.6 256.1 159.6 226.4 415.1 260.8 217.9 261.2 290.8 309.7 408.8 197.3 286.5 279.9 324.9 255.7 400.6 332.8 247.6 146.1 157.8 492.8 282.7 254.7 324.6 187.4 255.7 275.1 210.8 214.3 247.3 315.7 233.8 187.1 165.3 242.0 212.7 272.1 251.5 289.0 355.8 257.2 322.4 318.0 410.1 264.8 310.1 169.0 239.5 132.6 188.2 265.1 160.0 172.8 162.0 181.0 263.1 173.6 133.0 129.5 89.0 182.7 319.8 183.2 295.2 352.3 102.3 109.6 104.1 114.8 114.4 117.5 109.2 104.3 121.9 105.4 112.6 112.6 137.4 67.3 67.9 8.1 122.9 206.0 224.5 293.5 80.2 102.6 116.3 141.0 263.8 81.5 158.8 80.9 54.2 367.2 128.2 194.6 348.3 276.0 422.3 137.2 158.2 127.0 146.0 129.2 14.7 267.4 327.5 146.8 71.4 122.5 93.8 146.9 81.4 123.1 296.9 77.4 15.4 183.9 219.7 93.1 169.5 1164.7 118.4 126.9 199.3 10.3 224.0 179.8 143.2 8.0 19.8 296.8 181.2 117.8 178.9 255.0 305.7 332.4 128.5 120.4 151.2 106.6 221.1 305.1 135.4 120.3 212.3 570.3 133.0 201.0 182.5 218.7 PTGER3 "EP3, lnc003875" ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047808 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 95.2;kidney: 81.2;smooth muscle: 68.0" "Group enriched" "Detected in many" 7 "Distal tubular cells: 225.0;Langerhans cells: 79.8" "Group enriched" "Detected in some" 7 "breast cancer: 4.1;renal cancer: 9.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 59 "basophil: 43.3" "Lineage enriched" "Detected in single" 59 "granulocytes: 43.3" "Cell line enhanced" "Detected in some" "ASC diff: 28.6;HAP1: 20.9;HDLM-2: 32.8;HEL: 15.6;T-47d: 72.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "HPA010689: AB_1855883" "unprognostic (1.53e-3)" "unprognostic (3.48e-1)" "unprognostic (1.11e-1)" "unprognostic (3.86e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (4.80e-2)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (8.83e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-4)" 54.5 6.7 7.1 5.0 4.3 0.2 28.6 0.0 8.5 4.7 10.4 13.9 1.2 95.2 3.7 3.9 10.1 8.9 1.6 4.7 10.9 81.2 0.3 1.0 1.3 5.6 0.6 1.7 6.6 0.9 0.6 0.6 3.2 3.0 2.3 0.7 11.9 7.9 0.4 13.8 3.7 68.0 2.4 0.3 22.4 1.0 4.7 0.9 1.0 1.4 1.4 6.6 6.1 1.1 0.0 0.0 0.0 0.0 28.6 0.7 0.1 0.7 0.0 0.1 0.7 0.0 0.0 0.0 0.0 3.5 0.0 0.0 20.9 0.0 0.1 32.8 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.1 0.0 0.3 0.0 0.2 72.5 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.1 7.2 0.0 43.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 7.1 4.3 0.0 8.5 4.7 10.9 5.6 0.6 3.2 2.4 4.7 1.1 6.9 0.0 0.5 0.0 0.0 5.0 0.2 0.0 0.0 1.6 13.7 6.1 1.8 1.5 0.0 20.2 0.0 0.0 0.2 0.4 225.0 3.0 1.6 0.6 4.6 1.7 2.4 0.0 2.2 0.0 2.4 12.2 1.5 1.2 9.5 0.0 0.7 0.0 0.1 3.3 3.4 1.0 12.2 0.0 79.8 1.0 1.2 3.2 8.8 0.0 0.6 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.1 1.3 0.1 7.2 0.0 0.2 6.6 0.5 11.7 0.1 0.1 0.1 7.5 0.1 1.2 6.2 0.0 0.2 PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 312.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.3;Hepatocytes: 577.4;Proximal enterocytes: 333.3;Proximal tubular cells: 303.7" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 85: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" 24.8 14.7 23.7 7.5 24.3 23.4 18.7 24.5 29.8 14.3 37.7 49.5 52.1 14.9 22.3 16.2 18.7 15.4 62.9 28.5 24.1 58.2 312.0 12.9 11.5 24.1 24.2 23.0 42.5 14.5 9.3 8.1 22.9 19.8 39.2 7.5 18.6 9.7 42.3 16.8 55.1 9.5 23.0 13.1 98.2 9.1 24.9 25.9 14.7 30.5 10.7 15.9 12.8 23.5 60.5 24.8 36.6 34.1 21.5 16.6 21.4 21.0 19.4 44.7 39.6 30.3 22.4 37.2 24.9 30.0 15.7 42.0 49.1 26.6 24.3 21.3 77.8 33.2 43.9 33.8 41.7 24.8 14.4 21.7 21.8 18.6 14.7 31.2 12.1 56.2 58.2 28.4 23.8 54.2 78.9 39.2 35.7 70.0 33.9 80.1 39.2 30.6 32.9 25.2 69.0 22.5 45.6 23.6 29.6 28.1 63.2 56.0 14.3 21.9 51.1 19.1 35.6 25.7 26.7 60.6 24.6 34.9 17.7 0.0 1.2 2.9 2.3 0.6 2.1 2.5 1.8 2.4 2.1 2.7 1.8 1.5 0.7 1.5 0.6 6.3 3.1 1.2 23.7 24.3 24.5 29.8 28.5 24.1 24.1 24.2 22.9 23.0 24.9 23.5 10.9 3.2 7.2 8.1 8.2 8.4 20.0 10.6 15.4 6.1 50.3 51.1 35.8 138.7 6.0 25.8 4.2 60.1 7.3 187.3 166.3 16.5 18.7 11.8 16.9 14.1 18.7 55.9 5.9 10.3 36.6 17.0 65.7 17.4 4.5 32.4 46.8 577.4 34.9 0.0 7.1 85.1 2.0 19.2 9.4 38.8 31.1 8.1 12.4 5.6 2.7 45.5 13.4 4.5 1.0 10.2 143.4 35.0 20.9 28.1 333.3 303.7 2.1 7.3 19.7 7.5 14.8 44.9 30.2 31.2 10.7 28.5 8.1 12.4 158.6 23.2 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 RAB3C ENSG00000152932 "RAB3C, member RAS oncogene family" Q96E17 5 58582221-58859394 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 62.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 140.6;Inhibitory neurons: 509.9;Oligodendrocyte precursor cells: 131.2" "Cancer enhanced" "Detected in some" "glioma: 1.0;pancreatic cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.7;HEL: 2.5;NB-4: 1.6;SCLC-21H: 10.2;SH-SY5Y: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, HPA048156" Enhanced Approved Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA003160: AB_1079731, HPA048156: AB_2680291" "unprognostic (1.30e-1)" "unprognostic (3.35e-2)" "unprognostic (9.94e-2)" "unprognostic (2.23e-2)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (8.73e-3)" "unprognostic (3.40e-2)" "unprognostic (6.90e-2)" "unprognostic (7.58e-2)" "unprognostic (9.52e-4)" "unprognostic (1.51e-3)" "unprognostic (3.70e-5)" "unprognostic (4.70e-2)" "unprognostic (1.05e-1)" "unprognostic (9.65e-2)" "unprognostic (3.61e-3)" 1.1 9.0 19.1 1.2 20.6 0.0 0.7 0.9 32.7 0.1 0.0 0.6 1.6 0.7 0.0 0.2 0.2 0.7 0.1 10.2 62.5 0.0 0.1 0.1 0.2 7.4 12.3 0.3 1.7 0.1 6.8 0.1 31.6 0.0 0.8 6.0 0.1 0.0 0.1 0.0 1.8 0.7 3.9 0.0 0.9 0.1 19.2 0.1 0.1 0.0 0.2 0.6 0.2 3.8 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.2 3.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 20.6 0.9 32.7 10.2 62.5 7.4 12.3 31.6 3.9 19.2 3.8 8.6 0.0 0.6 10.1 0.4 0.1 0.0 0.0 0.0 28.3 0.3 0.3 0.7 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.9 0.1 20.0 0.0 0.1 12.1 57.6 1.3 140.6 9.6 0.8 0.2 0.0 0.0 2.5 0.0 5.7 1.2 0.1 3.3 509.9 5.5 0.0 0.9 1.1 11.8 0.9 0.1 1.8 6.5 0.0 1.6 0.0 131.2 8.4 3.9 1.2 0.7 0.0 0.0 0.3 0.1 0.0 6.7 13.1 0.5 0.2 2.4 4.1 0.0 0.1 0.0 1.3 0.1 0.3 0.0 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 20.8;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 18.1;granulocytes: 26.6;Hofbauer cells: 15.1;Kupffer cells: 32.9;Langerhans cells: 11.6;Macrophages: 19.1;monocytes: 25.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 39.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 25.7;HMC-1: 24.0;U-937: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: AB_10961405" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.23e-4)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (4.56e-1)" "unprognostic (2.66e-2)" 3.2 0.8 0.3 6.7 0.3 20.8 0.7 0.3 0.9 1.1 0.4 1.2 1.2 0.5 0.1 1.0 1.0 1.9 0.6 0.2 0.3 0.3 0.7 3.3 1.1 0.9 0.4 0.4 1.1 0.3 0.2 2.3 0.6 0.5 0.8 0.0 0.4 0.5 0.8 0.5 1.8 2.0 0.7 8.9 0.9 0.2 1.1 1.1 0.2 1.4 0.7 2.5 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.7 0.0 0.0 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 12.5 13.5 20.1 0.0 15.4 0.0 0.1 0.3 0.0 9.4 0.1 0.0 0.0 39.4 0.0 17.9 0.7 1.4 4.4 0.3 0.3 0.3 0.9 0.2 0.3 0.9 0.4 0.6 0.7 1.1 1.0 0.2 0.0 0.6 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.3 18.1 0.0 1.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.7 0.0 0.2 0.4 0.0 0.0 26.6 0.0 1.4 0.0 15.1 0.0 0.4 0.0 0.0 32.9 11.6 0.0 0.0 19.1 1.8 0.0 25.7 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.3 1.5 0.0 0.0 0.1 RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 121.8;Endothelial cells: 83.9;Hepatic stellate cells: 94.2;Theca cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 14.7;HeLa: 13.9;HUVEC TERT2: 38.5;SiHa: 21.1;TIME: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA077251: AB_2732337" "unprognostic (9.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-2)" "prognostic favorable (7.17e-5)" "unprognostic (8.44e-2)" "unprognostic (2.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.46e-4)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" 24.4 7.0 5.9 2.6 4.3 0.7 21.0 4.4 4.6 9.2 1.4 5.6 2.5 11.2 1.1 5.1 9.9 3.8 18.8 3.6 4.0 12.6 2.6 27.9 2.2 4.9 5.3 4.9 13.2 1.6 4.1 7.9 5.9 5.5 0.7 0.1 4.8 2.7 7.7 6.0 5.7 4.2 4.5 16.8 10.3 6.8 7.3 1.5 10.5 4.0 1.4 7.6 7.7 3.6 10.2 0.1 0.2 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.6 1.1 0.8 2.2 0.0 0.0 2.5 0.2 2.2 0.0 0.0 14.7 0.2 13.9 0.4 2.2 0.0 0.7 2.2 1.2 0.0 0.0 0.0 38.5 1.3 1.3 0.1 0.0 0.9 0.0 1.3 0.3 0.4 0.0 0.2 0.0 0.4 0.0 0.8 6.7 0.5 21.1 0.0 0.0 0.1 0.1 0.0 52.4 0.0 0.4 0.2 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 4.3 4.4 4.6 3.6 4.0 4.9 5.3 5.9 4.5 7.3 3.6 121.8 0.0 1.3 0.0 1.2 6.5 5.7 2.0 0.6 1.1 5.9 10.8 7.3 1.5 1.2 1.8 0.0 0.4 0.7 0.1 0.0 0.7 5.9 3.2 4.8 83.9 0.0 2.7 3.4 0.7 1.9 9.5 2.0 3.8 0.0 6.0 94.2 1.9 0.7 6.7 1.1 0.1 4.1 6.3 3.0 5.2 10.2 1.0 19.6 16.9 0.0 2.1 0.0 1.5 1.5 0.8 0.0 11.3 1.4 10.1 0.2 0.3 2.1 0.7 19.7 1.9 6.2 1.0 11.0 3.7 6.0 0.3 1.0 40.2 0.2 6.4 RASL10B "RRP17, VTS58635" ENSG00000270885 "RAS like family 10 member B" Q96S79 17 35731639-35743521 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3;skeletal muscle: 31.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 13.8;Early spermatids: 10.4;Late spermatids: 34.6;Muller glia cells: 29.0" "Cancer enhanced" "Detected in many" "testis cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 24.3;HHSteC: 26.7;NTERA-2: 41.3;REH: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046842, HPA057092" Enhanced Approved Vesicles NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA046842: AB_2679835, HPA057092: AB_2683332" "unprognostic (5.78e-2)" "unprognostic (2.15e-2)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (8.60e-2)" "unprognostic (1.24e-1)" "unprognostic (2.69e-2)" "unprognostic (4.98e-2)" "unprognostic (1.97e-2)" "unprognostic (7.13e-2)" "unprognostic (2.61e-2)" "unprognostic (3.18e-2)" "unprognostic (1.71e-6)" "unprognostic (2.41e-3)" "unprognostic (1.00e-1)" "unprognostic (1.32e-2)" "unprognostic (9.60e-3)" 15.4 1.7 25.9 0.1 32.3 0.0 11.3 8.7 25.6 3.9 7.6 1.9 0.7 2.8 0.6 0.4 3.9 0.7 19.3 26.5 18.1 3.0 2.1 1.2 0.1 16.5 19.2 3.7 4.9 5.2 6.7 2.8 18.0 2.9 0.1 9.0 9.1 14.7 31.5 0.8 1.2 0.7 13.2 0.3 1.8 3.0 17.5 0.4 1.7 0.9 0.1 1.4 2.3 12.9 0.0 0.3 6.3 0.0 1.1 0.6 1.8 1.2 0.8 4.3 3.6 8.1 0.0 0.0 0.7 0.2 0.0 0.0 24.3 0.0 1.5 0.0 8.0 0.0 4.1 9.3 26.7 0.0 0.0 19.5 1.5 1.5 0.0 3.4 0.0 13.2 5.5 0.0 0.3 0.5 11.6 0.0 41.3 0.0 0.0 20.8 11.1 18.5 0.0 0.0 18.3 17.8 1.2 0.4 1.7 17.8 2.3 1.2 0.0 2.0 14.5 0.1 0.5 0.0 0.0 5.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 32.3 8.7 25.6 26.5 18.1 16.5 19.2 18.0 13.2 17.5 12.9 0.3 0.0 0.5 0.3 0.0 0.1 0.5 0.0 0.0 3.9 2.7 1.4 13.8 4.3 0.0 1.8 2.1 0.0 0.0 0.0 0.0 1.3 10.4 1.0 0.7 0.7 0.0 0.0 2.6 0.0 0.0 1.9 0.0 1.4 0.0 2.8 0.0 6.7 0.2 6.7 4.9 0.2 0.0 0.6 0.0 34.6 2.1 0.1 0.0 1.0 0.0 29.0 0.0 0.5 0.5 0.3 0.0 3.0 0.0 0.6 0.4 0.1 0.0 1.2 0.0 1.5 2.3 4.8 0.9 0.0 0.0 0.3 0.1 7.0 0.4 0.2 RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 77.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.0;monocytes: 258.7;Muller glia cells: 260.3;Proximal tubular cells: 128.0;Skeletal myocytes: 186.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 84.8;intermediate monocyte: 63.9;myeloid DC: 84.2;non-classical monocyte: 37.9" "Group enriched" "Detected in many" 10 "dendritic cells: 84.2;monocytes: 84.8" "Cell line enhanced" "Detected in many" "Karpas-707: 64.3;RH-30: 162.7;RPMI-8226: 54.9;U-937: 85.4;WM-115: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: AB_10795576, HPA077069: " "unprognostic (1.83e-1)" "unprognostic (8.21e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (5.14e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (4.83e-2)" "unprognostic (8.75e-3)" "unprognostic (4.20e-1)" "unprognostic (4.11e-3)" "unprognostic (4.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.42e-1)" "unprognostic (6.20e-2)" 35.3 7.1 57.4 21.7 67.9 8.3 22.7 64.3 58.6 6.5 43.8 18.5 13.6 3.0 8.6 4.7 6.0 10.8 44.8 53.9 58.9 77.3 17.1 11.9 19.7 63.4 64.0 3.6 39.5 5.0 13.0 12.7 65.9 7.9 6.0 26.9 16.7 10.9 14.8 4.8 13.8 8.7 55.8 20.1 9.4 9.0 65.3 10.4 40.7 17.6 9.1 11.4 7.0 69.7 1.4 0.3 6.0 11.4 17.9 1.0 4.1 0.7 1.1 2.0 3.5 5.0 0.6 0.1 2.3 0.8 3.9 0.0 2.6 2.8 2.8 37.8 0.0 0.1 0.2 39.7 19.0 2.6 0.0 13.1 0.0 1.9 0.2 10.9 3.0 1.6 0.0 64.3 2.9 0.0 3.0 43.1 1.2 0.2 1.2 8.1 162.7 54.9 0.4 1.2 1.0 0.8 0.0 0.5 2.0 10.7 1.1 32.4 0.0 0.4 3.6 3.0 6.5 0.7 0.7 0.1 18.9 85.4 54.8 0.0 84.8 0.1 8.7 63.9 0.2 0.0 0.6 3.7 84.2 0.0 0.6 2.6 3.0 6.9 37.9 2.2 0.3 48.9 57.4 67.9 64.3 58.6 53.9 58.9 63.4 64.0 65.9 55.8 65.3 69.7 8.9 19.2 17.2 77.4 3.7 3.7 1.4 3.2 1.2 22.5 9.7 7.0 47.9 37.1 13.1 16.5 4.2 1.2 20.3 10.1 17.6 45.3 1.4 6.4 13.7 9.2 11.5 0.0 17.0 3.8 1.2 28.6 1.5 14.8 1.3 4.2 6.1 20.1 157.0 37.0 33.6 7.4 12.2 84.7 94.3 4.4 10.5 91.0 8.8 35.6 258.7 260.3 54.6 37.7 38.2 4.0 11.3 2.2 4.1 1.0 45.0 128.0 5.9 13.3 26.3 186.4 25.9 0.6 1.9 0.8 1.7 2.6 8.0 4.9 15.0 0.7 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 RCL1 "RNAC, RPCL1" ENSG00000120158 "RNA terminal phosphate cyclase like 1" Q9Y2P8 9 4792944-4885917 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.8" "Cell type enhanced" "Detected in many" "Early spermatids: 74.1;Hepatocytes: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "HDLM-2: 145.5;HEL: 375.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071308 Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA071308: AB_2686384" "prognostic favorable (5.48e-4)" "unprognostic (7.60e-3)" "unprognostic (7.55e-2)" "unprognostic (4.19e-2)" "unprognostic (1.07e-2)" "unprognostic (3.29e-1)" "prognostic favorable (8.02e-4)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.59e-2)" "prognostic favorable (2.40e-7)" "unprognostic (1.01e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-1)" "unprognostic (3.66e-2)" 37.2 13.4 5.8 9.0 7.8 44.3 21.7 6.5 7.3 9.4 8.2 7.5 4.1 8.3 9.9 10.4 10.6 6.3 6.6 5.9 8.0 12.3 245.8 13.1 15.0 8.4 7.9 17.6 64.6 8.7 7.0 13.8 8.8 7.0 7.5 3.8 6.8 7.1 14.4 21.1 8.0 7.7 8.3 9.2 10.4 13.8 8.1 9.7 8.2 8.6 12.5 12.5 10.6 10.2 23.3 27.6 10.3 16.5 15.0 10.1 27.3 10.8 12.0 19.9 16.8 13.9 13.4 45.2 7.4 9.7 22.1 14.4 48.0 32.5 22.8 145.5 24.2 375.0 33.5 28.1 21.5 34.1 28.9 22.4 18.2 19.0 28.7 11.2 19.7 32.4 38.9 28.0 12.0 30.4 27.8 57.8 35.7 27.7 11.0 34.2 13.8 24.2 24.3 25.9 29.6 24.3 13.6 20.0 15.8 20.4 18.9 39.8 13.9 11.6 13.3 16.6 34.0 11.5 35.3 48.1 21.3 20.8 8.1 16.2 1.6 4.3 5.7 2.5 7.0 8.7 6.5 7.7 4.3 11.5 8.7 9.0 0.6 12.1 1.3 7.4 5.9 3.7 5.8 7.8 6.5 7.3 5.9 8.0 8.4 7.9 8.8 8.3 8.1 10.2 10.9 6.4 6.8 18.9 14.7 25.5 21.8 11.9 25.0 5.4 9.3 8.0 10.6 11.5 7.8 3.7 0.0 39.8 8.5 3.0 25.4 12.4 74.1 8.3 8.8 12.1 3.0 68.4 14.1 11.5 16.6 11.9 8.6 5.7 14.5 16.7 16.1 183.4 17.7 5.0 15.9 6.4 6.1 11.3 6.2 39.7 23.0 7.6 3.6 36.5 9.7 9.2 5.2 18.1 34.3 10.6 3.7 37.6 14.3 18.1 3.2 13.7 14.0 7.0 13.1 19.1 10.2 18.2 18.4 18.6 21.2 35.4 8.9 12.1 8.9 16.6 RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 94.5;liver: 58.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Proximal enterocytes: 49.9;Rod photoreceptor cells: 62.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.5;ASC TERT1: 24.3;hTEC/SVTERT24-B: 15.3;hTERT-RPE1: 24.5;LHCN-M2: 15.4;U-87 MG: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" 94.5 1.8 2.2 4.1 2.5 1.0 34.2 2.2 2.6 2.5 3.5 13.6 18.5 4.2 7.8 3.1 4.6 4.2 9.2 2.0 2.2 9.0 58.9 1.9 1.8 2.7 2.5 2.1 3.5 0.3 1.7 0.6 2.4 4.4 4.4 3.2 3.3 2.2 6.1 2.7 15.5 19.5 2.5 2.2 5.9 2.4 2.8 0.9 2.7 7.6 0.7 5.5 2.2 3.4 0.7 1.4 0.8 0.5 28.5 24.3 0.6 3.8 4.2 0.7 1.4 0.5 7.9 1.0 0.7 2.1 0.2 0.3 0.3 0.1 0.6 1.0 1.3 0.1 2.0 2.1 0.8 0.1 0.3 10.5 1.0 15.3 0.1 24.5 0.3 0.5 0.2 1.3 15.4 0.7 0.4 0.2 0.3 3.7 2.3 0.6 0.4 0.5 0.2 0.8 0.2 1.1 0.2 0.5 3.4 0.2 0.7 0.6 0.5 1.5 1.5 1.1 0.9 1.1 0.5 0.2 26.7 0.4 0.3 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.2 0.3 0.2 0.5 0.0 0.0 2.2 2.5 2.2 2.6 2.0 2.2 2.7 2.5 2.4 2.5 2.8 3.4 2.5 9.6 2.2 0.0 4.6 1.9 4.5 3.9 0.6 24.3 2.7 5.0 3.9 10.0 2.4 1.8 62.6 2.2 5.3 23.5 1.9 2.1 0.8 1.8 2.9 3.7 11.5 0.0 0.0 2.6 1.2 3.9 11.2 1.5 0.0 4.9 3.6 18.4 0.6 16.8 0.0 10.3 0.0 4.5 7.9 2.3 13.4 2.3 5.4 0.0 4.7 8.2 12.3 0.0 0.0 3.6 18.6 6.8 0.7 3.2 49.9 13.0 4.7 62.9 13.1 14.0 9.3 3.9 6.4 0.8 1.7 1.5 4.8 5.3 15.9 3.1 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85341955-85354531 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 247.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Proximal enterocytes: 249.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007961, HPA046513" Uncertain Uncertain Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA007961: AB_1079802, HPA046513: AB_2679680" "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (5.84e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "prognostic favorable (4.23e-4)" "unprognostic (1.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.95e-10)" "unprognostic (2.73e-2)" "unprognostic (5.34e-1)" "unprognostic (8.24e-3)" "unprognostic (9.90e-2)" 247.0 52.3 16.5 17.6 20.9 3.8 63.9 19.8 15.8 18.9 27.3 89.6 167.0 16.0 38.4 36.9 15.7 32.0 20.3 14.9 20.0 54.9 115.9 24.6 11.7 21.0 20.0 17.0 37.5 36.9 7.2 11.6 20.0 32.5 73.5 9.5 27.8 23.6 68.3 48.8 142.4 22.0 19.2 11.7 60.9 14.6 19.9 12.2 47.4 55.1 19.9 19.0 23.7 23.7 52.7 30.1 16.8 40.0 197.8 37.0 22.1 37.8 46.5 22.5 31.5 20.9 36.2 18.5 30.3 29.6 17.9 42.6 22.9 65.6 21.6 22.8 15.9 9.0 23.5 50.6 47.6 17.9 19.3 48.6 87.2 28.7 38.1 51.4 37.6 15.4 9.7 43.1 42.0 11.0 12.5 9.0 5.6 52.6 36.2 8.1 33.7 23.9 39.1 30.1 8.3 13.8 31.4 59.9 101.8 11.2 28.2 2.9 30.0 25.3 13.8 23.5 19.9 23.0 22.9 7.2 30.9 20.5 17.6 0.0 3.8 1.8 4.8 4.0 6.2 2.6 3.5 6.0 4.0 1.5 2.5 2.5 3.7 5.1 8.7 2.7 4.2 3.4 16.5 20.9 19.8 15.8 14.9 20.0 21.0 20.0 20.0 19.2 19.9 23.7 7.3 28.9 29.6 5.9 4.5 11.3 10.8 18.6 12.5 3.7 13.0 7.9 21.7 21.5 15.5 12.9 18.8 10.9 4.3 264.9 0.0 23.7 27.6 9.7 6.8 9.7 10.8 2.5 5.7 36.1 6.5 9.0 56.1 16.6 10.8 5.5 7.5 54.7 9.9 11.8 4.5 45.0 8.2 10.4 8.6 60.0 14.6 7.4 30.2 7.5 8.3 8.3 10.3 6.6 12.1 32.7 79.2 12.4 10.3 11.8 249.9 17.8 11.9 4.9 0.0 7.7 8.8 2.9 3.1 24.9 14.9 8.5 7.7 9.9 56.6 9.8 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117171 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 496.2;liver: 1536.9" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1579.1" "Group enriched" "Detected in all" 5 "liver cancer: 162.2;renal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 191.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favorable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 50.1 48.4 93.1 11.4 96.4 7.5 19.1 95.5 131.7 11.2 83.8 24.5 30.5 8.4 22.7 14.3 9.4 22.7 32.3 89.2 95.0 496.2 1536.9 9.5 10.1 91.6 97.8 23.4 27.0 24.6 10.0 10.8 95.5 19.3 24.6 26.6 16.4 11.6 40.0 10.6 21.8 10.8 92.6 7.4 24.8 17.2 100.0 11.2 15.9 41.0 12.3 15.5 7.9 91.0 44.0 37.5 29.3 36.6 65.5 50.4 33.0 39.7 28.0 26.4 31.0 51.4 28.4 62.5 49.6 29.4 34.5 30.8 65.4 56.9 52.5 22.3 28.6 45.0 25.6 55.6 29.9 17.6 7.0 44.4 19.5 36.6 39.9 32.4 34.2 65.3 82.7 12.9 35.5 57.8 35.6 50.1 47.0 191.4 67.8 41.0 21.7 18.4 64.6 31.6 32.2 15.7 25.5 17.4 29.2 37.4 44.5 23.5 20.9 20.6 12.5 33.7 16.3 31.2 46.1 30.9 35.0 39.0 13.2 0.2 9.0 5.6 6.6 7.8 8.7 13.8 9.4 10.1 11.1 11.5 12.0 13.0 1.9 10.3 8.3 8.5 13.9 8.1 93.1 96.4 95.5 131.7 89.2 95.0 91.6 97.8 95.5 92.6 100.0 91.0 7.8 25.6 22.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 13.8 15.1 0.0 0.0 1.8 47.8 0.0 31.1 3.2 0.0 285.7 19.7 0.0 25.1 12.3 5.0 0.0 0.0 0.0 8.5 29.9 7.9 0.0 9.4 2.5 17.7 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.8 0.0 0.0 1579.1 5.8 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 14.4 6.3 22.3 0.0 0.0 RNF157 KIAA1917 ENSG00000141576 "Ring finger protein 157" Q96PX1 17 76142465-76240493 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 86.9;retina: 59.0;skeletal muscle: 73.9;testis: 31.4;tongue: 43.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 114.1;Cone photoreceptor cells: 189.7;Excitatory neurons: 64.6;Horizontal cells: 180.0;Inhibitory neurons: 92.7;Rod photoreceptor cells: 70.9" "Cancer enhanced" "Detected in many" "glioma: 11.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.2;T-cells: 5.8" "Cell line enhanced" "Detected in many" "HDLM-2: 100.9;U-266/70: 50.6;U-266/84: 45.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021854, HPA021991, HPA023922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" Vesicles "HPA021854: AB_10600307, HPA021991: AB_10601112, HPA023922: AB_10602202" "unprognostic (4.21e-1)" "unprognostic (4.62e-2)" "unprognostic (1.55e-2)" "unprognostic (2.63e-3)" "unprognostic (4.93e-2)" "unprognostic (5.06e-2)" "unprognostic (2.07e-3)" "unprognostic (4.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (1.04e-3)" "unprognostic (4.02e-1)" "unprognostic (8.26e-2)" "unprognostic (8.69e-3)" "unprognostic (2.28e-1)" "unprognostic (2.75e-2)" "unprognostic (1.38e-1)" 13.6 3.3 36.4 3.7 39.1 2.2 4.9 34.1 86.9 1.4 9.8 9.8 9.6 1.4 3.4 1.0 1.8 1.3 6.4 56.9 34.5 5.8 2.5 1.4 5.2 59.7 41.9 1.2 3.4 14.6 6.3 1.6 61.1 1.9 7.0 59.0 1.9 1.5 73.9 1.0 10.3 1.8 34.1 3.5 3.9 31.4 51.5 2.8 3.4 43.7 2.7 3.0 1.0 58.1 0.2 7.1 29.3 10.7 8.8 4.4 13.4 0.3 8.9 1.9 1.3 3.3 3.1 0.0 4.2 0.5 6.9 0.2 26.0 0.1 1.6 100.9 8.9 0.0 2.9 4.7 1.7 1.4 10.9 2.4 0.1 3.7 0.1 1.5 0.2 4.7 16.0 0.3 3.6 8.0 4.4 0.8 4.8 5.5 21.1 0.0 0.3 0.1 3.4 3.2 5.1 24.0 5.3 0.1 11.5 6.5 0.7 5.1 0.2 1.9 2.3 14.4 9.6 50.6 45.5 0.1 0.8 0.1 15.1 2.2 0.2 0.3 1.6 0.1 3.4 0.2 3.4 2.7 0.1 0.4 5.8 3.9 1.2 0.7 0.2 0.3 1.3 1.0 36.4 39.1 34.1 86.9 56.9 34.5 59.7 41.9 61.1 34.1 51.5 58.1 2.8 3.2 3.3 33.3 1.5 2.0 0.8 0.2 0.6 114.1 0.8 0.9 9.0 11.5 1.3 1.8 189.7 0.6 5.0 5.3 0.0 1.9 27.8 0.6 3.7 4.4 2.4 5.5 64.6 1.1 0.4 3.1 0.0 1.5 0.0 0.9 0.7 4.3 0.4 180.0 92.7 7.4 0.0 0.8 6.0 29.1 11.5 1.1 1.8 3.7 1.4 35.9 8.2 62.8 35.0 0.1 3.4 13.9 2.1 0.9 19.3 9.1 0.7 70.9 0.0 2.9 1.3 22.7 25.0 0.0 2.3 0.3 15.5 1.3 18.2 1.5 RNPEPL1 ENSG00000142327 "Arginyl aminopeptidase like 1" Q9HAU8 2 240565804-240581372 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036772, HPA036773" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA036772: AB_10670848, HPA036773: " "unprognostic (3.92e-2)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.39e-1)" "unprognostic (5.24e-3)" "prognostic favorable (7.43e-4)" "prognostic unfavorable (5.06e-4)" "unprognostic (3.72e-3)" "unprognostic (9.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (5.31e-2)" "unprognostic (9.86e-2)" 40.3 31.4 29.1 14.1 29.6 21.7 32.0 29.0 38.7 15.6 27.0 39.6 20.2 16.8 5.6 52.4 17.0 12.1 79.4 27.9 27.8 42.7 50.6 35.9 23.8 31.5 30.0 12.0 64.2 10.9 9.1 10.6 30.3 34.7 9.5 0.8 28.9 13.1 63.7 35.3 39.8 9.4 31.0 56.4 48.4 9.9 31.4 15.9 19.2 17.1 12.1 34.1 23.2 31.1 13.7 22.4 4.9 13.2 17.6 18.1 16.6 8.6 21.1 9.5 11.6 6.3 39.3 3.9 4.3 21.8 13.3 14.6 5.5 16.1 0.9 23.9 7.7 9.0 7.3 37.2 44.1 5.9 15.5 21.6 25.5 4.9 9.6 15.1 32.8 15.2 6.8 25.7 6.5 19.3 7.5 22.4 6.5 26.5 9.0 15.5 7.4 33.3 39.3 18.5 4.6 9.8 5.8 19.7 39.9 5.6 13.9 26.8 22.7 10.2 10.4 14.4 10.0 24.1 3.9 4.8 20.9 16.6 15.7 9.2 11.2 30.5 14.8 9.9 12.7 8.2 11.3 13.4 8.2 8.7 6.4 9.5 20.0 10.7 10.1 9.5 14.7 7.9 29.1 29.6 29.0 38.7 27.9 27.8 31.5 30.0 30.3 31.0 31.4 31.1 27.9 22.4 25.7 10.4 27.8 7.8 15.0 8.4 2.8 6.4 18.8 9.1 35.6 24.3 12.9 12.9 0.0 7.1 80.4 138.9 17.6 24.6 3.1 12.1 11.0 22.7 26.4 22.3 9.5 49.6 6.8 12.3 104.5 27.4 34.2 31.8 30.0 42.2 43.8 3.3 8.6 58.7 8.2 74.3 21.0 5.9 8.7 47.1 23.2 9.4 52.0 15.9 79.3 5.5 10.3 65.0 70.0 13.5 20.5 20.2 77.1 35.6 7.2 6.9 13.1 14.8 16.4 1.3 8.2 13.0 9.2 5.1 47.9 17.4 60.5 23.0 RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 514.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1074.7" "Group enriched" "Detected in all" 6 "granulocytes: 1074.7;monocytes: 400.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA015649: AB_1856498, HPA015650: AB_1856499" "unprognostic (8.11e-3)" "unprognostic (8.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.88e-3)" "unprognostic (1.41e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (5.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.87e-4)" "unprognostic (1.60e-2)" "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-2)" 207.5 81.8 361.4 54.1 412.2 108.5 93.3 338.4 514.5 87.6 190.7 88.1 54.0 62.5 81.2 55.7 88.5 56.3 57.4 428.4 378.9 92.8 87.5 77.8 36.0 404.5 309.1 48.1 91.1 109.9 81.0 62.2 417.2 53.3 79.9 194.4 138.8 76.1 70.2 103.7 65.2 80.1 329.2 51.7 57.0 46.6 334.0 53.7 175.5 43.7 48.5 55.7 54.2 384.0 157.5 113.8 134.0 128.4 242.3 170.9 53.4 139.3 147.5 120.5 128.4 99.6 338.1 184.2 231.7 210.0 115.7 157.2 194.0 68.7 157.5 149.5 103.5 236.5 151.3 70.4 201.1 212.8 182.4 113.5 199.2 146.7 162.3 200.7 165.2 158.9 136.2 290.1 107.4 129.2 113.4 235.2 156.7 127.3 127.3 148.4 93.8 342.9 239.7 87.5 282.7 164.0 226.2 245.3 271.5 95.4 271.1 172.7 155.2 71.3 95.6 251.1 108.4 183.4 169.9 145.6 274.7 173.8 77.2 441.0 400.1 487.7 41.4 187.6 44.8 28.6 41.6 41.3 130.8 19.4 30.1 32.7 1074.7 41.7 240.4 79.0 68.6 323.0 361.4 412.2 338.4 514.5 428.4 378.9 404.5 309.1 417.2 329.2 334.0 384.0 62.8 134.6 67.5 110.7 35.9 144.5 103.5 63.0 101.3 157.7 125.2 59.9 36.1 81.5 91.9 244.6 70.9 68.6 55.6 118.2 29.4 154.4 35.8 96.4 74.3 68.1 99.8 85.8 398.8 117.1 105.6 96.7 60.1 129.2 77.3 71.4 85.6 81.3 143.7 82.4 372.7 83.5 122.1 178.3 110.8 71.2 79.2 151.4 113.8 100.2 178.0 150.3 42.2 200.6 294.8 103.3 82.0 89.9 94.8 79.4 94.5 55.9 156.0 97.6 78.9 53.1 78.6 194.7 133.5 85.9 146.2 86.5 48.8 51.7 96.5 99.8 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 218.9;Kupffer cells: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.5" "Group enriched" "Detected in many" 5 "granulocytes: 19.5;monocytes: 12.9" "Cell line enhanced" "Detected in many" "HaCaT: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 40.5 22.7 33.5 14.5 36.4 18.9 11.2 25.5 29.4 12.2 16.9 16.6 25.8 13.5 8.7 28.5 16.5 13.6 19.4 27.1 30.2 16.0 32.9 18.8 8.2 32.9 31.3 21.7 25.4 45.1 3.5 14.5 30.8 15.6 10.0 5.4 21.7 17.1 106.5 88.1 28.0 11.1 30.4 25.1 14.7 7.9 42.7 6.0 17.6 51.9 7.6 16.2 8.2 22.6 19.6 36.4 14.7 21.9 42.8 19.1 66.7 14.1 16.1 9.6 6.5 20.7 28.0 0.0 25.8 22.5 15.1 105.5 7.7 32.8 2.9 26.3 7.2 0.1 47.5 30.0 20.4 18.8 4.8 29.0 52.1 11.5 10.6 12.9 12.8 1.6 26.0 1.1 8.7 61.8 1.1 59.5 17.5 63.4 16.9 7.4 30.3 36.7 12.2 64.3 17.2 10.5 37.3 46.9 10.6 7.1 44.9 78.8 16.5 16.2 23.4 17.4 9.7 1.7 0.2 0.4 11.6 33.9 12.7 1.3 8.1 6.6 1.4 12.9 0.2 0.3 0.9 1.0 3.2 0.1 0.2 1.2 19.5 2.2 11.2 0.7 1.2 3.2 33.5 36.4 25.5 29.4 27.1 30.2 32.9 31.3 30.8 30.4 42.7 22.6 32.1 32.1 22.9 36.2 4.6 34.5 16.5 21.1 12.5 6.0 16.7 14.4 38.8 72.9 26.2 9.2 25.0 30.1 11.0 72.3 1.9 13.9 4.3 19.8 16.6 28.9 9.6 30.9 9.1 14.1 29.5 23.7 17.9 17.4 1.3 21.3 71.0 218.9 31.9 33.7 17.6 21.2 10.2 134.2 30.0 18.8 32.3 50.4 12.4 10.3 80.4 36.5 14.4 29.1 6.0 15.9 32.4 21.1 7.4 17.7 55.6 19.9 34.4 19.9 19.7 34.6 30.6 0.9 9.4 34.4 46.9 23.9 12.6 15.5 27.5 32.8 S100B S100beta ENSG00000160307 "S100 calcium binding protein B" P04271 21 46598604-46605208 "Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 1499.3;choroid plexus: 781.0" "Cell type enhanced" "Detected in many" "Astrocytes: 126.3;Breast myoepithelial cells: 124.8;Granulosa cells: 261.7;Langerhans cells: 206.8;Melanocytes: 99.6;Oligodendrocytes: 332.1" "Group enriched" "Detected in all" 58 "glioma: 463.5;melanoma: 495.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 360.9" "Lineage enriched" "Detected in all" 6 "T-cells: 360.9" "Group enriched" "Detected in some" 7 "SK-MEL-30: 547.1;WM-115: 992.8" "CAB000073, HPA015768, CAB078196" Enhanced Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 300000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "CAB000073: AB_10013383, CAB078196: AB_2665776, HPA015768: AB_1856538" "unprognostic (5.67e-3)" "unprognostic (6.39e-3)" "unprognostic (2.08e-3)" "unprognostic (2.08e-2)" "unprognostic (4.54e-3)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.68e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.57e-3)" "unprognostic (6.70e-2)" "unprognostic (4.41e-7)" "unprognostic (3.55e-2)" "unprognostic (7.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" 151.1 25.7 877.1 10.5 1072.5 2.3 87.0 1254.5 1191.2 28.6 781.0 121.0 7.4 2.4 12.1 14.6 6.9 14.3 28.1 858.4 989.0 3.6 3.2 6.4 21.4 1491.0 1054.2 5.6 5.0 0.3 44.7 0.8 1359.0 29.3 14.2 14.1 19.3 26.2 3.6 15.8 36.3 6.8 1162.2 26.2 23.6 2.4 998.8 18.4 5.2 6.4 20.3 15.9 26.9 1499.3 0.5 0.0 110.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.9 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 15.9 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 2.5 0.0 0.0 547.1 0.0 0.1 0.5 0.0 0.3 0.3 0.0 3.2 0.0 0.3 0.0 1.4 6.7 992.8 0.1 0.5 0.2 360.9 9.5 103.3 0.2 1.0 67.6 16.3 1.4 3.2 153.1 3.2 58.7 10.1 3.9 0.0 63.6 877.1 1072.5 1254.5 1191.2 858.4 989.0 1491.0 1054.2 1359.0 1162.2 998.8 1499.3 4.5 3.2 4.8 126.3 4.6 16.8 0.7 0.0 17.6 1.3 41.2 124.8 6.0 0.0 0.0 0.0 0.0 0.0 14.7 0.1 0.0 0.1 0.4 0.1 0.1 2.7 0.0 2.7 0.9 0.0 0.1 4.4 0.5 0.2 0.0 261.7 4.6 0.4 9.3 0.0 1.4 0.0 0.0 38.6 206.8 1.7 5.6 37.0 99.6 9.4 33.3 25.7 63.8 83.4 332.1 0.1 0.0 0.0 2.2 0.1 0.0 0.1 0.0 4.7 0.0 5.6 7.8 0.1 0.1 0.7 12.6 0.1 37.9 0.0 0.2 0.4 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 SAA1 "PIG4, SAA, TP53I4" ENSG00000173432 "Serum amyloid A1" P0DJI8 11 18266260-18269977 "Disease related genes, Predicted secreted proteins" "Acute phase" Heparin-binding Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 48144.3" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 99298.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 1249.6" "Group enriched" "Detected in some" 5 "midbrain: 3.8;pons: 2.6;thalamus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 716.4" "Secreted to blood" NA NA 300000000 11000000000 "Cluster 7: Monocytes - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (1.50e-1)" "unprognostic (4.54e-3)" "unprognostic (1.79e-2)" "unprognostic (1.63e-2)" "unprognostic (7.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-2)" "unprognostic (8.95e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.57e-12)" "unprognostic (5.15e-2)" "unprognostic (9.78e-2)" "unprognostic (9.23e-3)" "unprognostic (1.64e-1)" 2040.4 54.4 0.1 161.7 0.2 0.0 1382.7 0.1 0.6 258.0 1.8 40.3 1.4 2.2 0.2 51.1 56.6 33.6 23.2 0.3 0.3 29.5 48144.3 98.5 1.1 0.8 3.8 3.3 46.7 0.5 66.6 7.2 2.6 66.5 6.4 0.0 2368.1 4.4 511.6 88.6 75.0 18.8 0.1 38.8 42.0 1.7 6.0 52.1 18.1 0.2 15.7 63.9 29.0 0.1 49.2 0.3 0.0 0.3 34.4 0.2 18.9 1.3 1.1 0.2 0.3 0.1 17.2 0.0 38.3 0.0 11.7 45.5 0.0 716.4 0.3 0.6 0.0 0.8 0.0 0.1 148.4 1.1 0.0 60.9 66.7 0.2 76.7 0.1 0.0 0.0 0.1 0.0 9.3 0.1 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 28.5 0.9 0.0 0.1 4.2 5.5 0.2 0.0 0.5 0.0 0.0 0.2 5.5 0.0 1.3 0.0 1.3 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.3 0.3 0.8 3.8 2.6 0.1 6.0 0.1 107.2 6.4 2.8 0.0 259.8 9.3 64.9 10039.5 10.2 0.0 210.6 1010.4 0.1 1701.5 7604.7 55.2 0.0 1.3 3.0 44.5 0.0 250.4 0.0 12.6 1.6 114.9 1.8 3543.7 0.1 81.1 34.4 8.3 0.0 14.3 2.5 0.0 2568.6 99298.7 1.0 0.0 0.1 5.2 2012.1 2454.9 0.3 0.0 0.0 2.6 51.6 0.0 2.6 0.0 1.0 0.0 0.1 68.8 5.5 0.0 0.1 185.5 3.1 0.2 15716.2 0.0 0.0 31.5 736.1 0.0 0.0 34.1 0.1 2.1 214.7 0.0 36.7 178.8 SASH3 "753P9, CXorf9, HACS2, SH3D6C, SLY" ENSG00000122122 "SAM and SH3 domain containing 3" O75995 X 129779949-129795201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 108.1;intestine: 36.5;lymphoid tissue: 120.7" "Cell type enhanced" "Detected in some" "B-cells: 69.5;dendritic cells: 66.3;Hofbauer cells: 51.3;Kupffer cells: 58.9;Macrophages: 40.0;monocytes: 45.3;NK-cells: 101.0;Plasma cells: 39.8;T-cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 164.1;JURKAT: 119.4;MOLT-4: 120.6;NB-4: 89.1;REH: 88.5;U-698: 150.2;U-937: 117.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001085 Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 14000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA001085: AB_2184289" "unprognostic (1.88e-2)" "unprognostic (5.82e-3)" "unprognostic (1.49e-3)" "prognostic favorable (3.15e-4)" "unprognostic (1.12e-1)" "unprognostic (1.19e-3)" "unprognostic (1.67e-1)" "unprognostic (3.23e-3)" "unprognostic (7.92e-3)" "unprognostic (3.45e-1)" "unprognostic (8.75e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.51e-5)" "unprognostic (3.30e-1)" "unprognostic (3.56e-2)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" 8.6 5.6 5.2 61.8 5.6 108.1 4.3 5.4 7.4 3.2 5.1 9.4 11.6 3.1 1.8 3.6 4.9 10.2 2.7 4.8 6.4 3.7 5.9 21.3 120.6 9.6 7.0 1.8 2.5 1.5 2.2 7.5 8.4 4.2 9.9 0.2 7.9 2.2 1.3 2.1 36.5 7.5 7.5 100.3 13.6 1.3 8.4 120.7 3.9 1.7 108.2 15.4 3.0 10.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.7 0.0 0.0 0.0 58.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 119.4 0.2 13.6 0.0 0.0 120.6 89.1 0.0 0.0 0.0 88.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 24.0 0.3 0.0 0.3 0.1 0.1 0.1 35.0 150.2 0.0 117.2 0.0 41.6 135.4 245.5 192.2 195.3 159.1 79.1 108.2 178.9 121.5 90.8 76.9 120.9 128.0 153.3 209.9 55.1 145.6 343.7 5.2 5.6 5.4 7.4 4.8 6.4 9.6 7.0 8.4 7.5 8.4 10.2 0.8 0.0 3.6 0.0 69.5 0.5 0.1 0.0 0.0 0.0 0.5 1.1 1.0 1.5 0.0 0.0 0.0 0.5 66.3 0.1 0.0 0.1 0.1 0.2 0.2 1.2 0.0 13.5 0.2 0.0 0.6 0.9 2.6 0.3 22.2 0.0 3.3 0.9 51.3 0.0 0.2 0.1 0.0 58.9 19.1 0.0 0.3 40.0 0.0 7.5 45.3 0.0 101.0 0.0 0.1 0.0 0.0 0.0 39.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.1 1.3 0.5 60.6 0.0 0.1 0.0 SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Endothelial cells: 51.3;Hepatic stellate cells: 62.4;Langerhans cells: 37.7;Microglial cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 12.1;REH: 11.5;TIME: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" 15.2 5.0 1.5 3.1 1.8 0.4 12.7 1.4 3.4 5.6 1.4 5.2 0.0 6.0 0.9 2.7 6.5 2.2 11.8 1.6 1.8 7.5 7.5 16.3 2.1 2.7 1.7 2.6 3.1 0.1 3.8 4.3 2.2 4.6 1.2 0.2 4.2 0.0 5.3 3.1 5.4 1.2 1.7 25.6 4.2 1.6 1.7 0.5 18.8 1.9 1.0 5.6 4.6 2.8 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.3 12.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 1.8 1.4 3.4 1.6 1.8 2.7 1.7 2.2 1.7 1.7 2.8 65.9 22.4 17.6 6.5 0.6 3.4 0.4 0.7 1.2 1.2 0.8 0.9 3.5 0.0 2.9 3.7 4.2 0.4 2.0 4.9 1.9 0.4 0.3 0.5 0.9 51.3 0.0 3.4 5.4 0.2 0.2 2.5 4.1 1.1 3.8 0.3 62.4 2.3 9.0 0.0 3.5 4.4 0.0 15.7 37.7 0.4 1.2 10.1 3.6 26.2 4.8 0.7 0.0 0.5 1.1 0.3 1.2 1.2 0.0 0.7 3.0 0.2 3.0 2.0 0.0 2.1 3.0 0.5 0.6 0.3 2.7 1.2 1.0 1.3 2.2 0.8 SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 430.3;Hepatic stellate cells: 286.3;Late spermatids: 740.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 355.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 355.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 398.1;TIME: 251.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" 66.7 54.2 42.6 44.6 63.3 65.5 57.6 75.4 60.7 39.5 36.3 19.5 21.8 24.6 28.2 31.5 27.3 34.3 50.2 49.5 57.5 42.0 25.3 66.9 49.7 64.0 63.0 20.7 30.8 25.1 27.9 76.7 54.6 18.3 19.8 19.0 35.0 16.8 94.1 20.5 21.7 27.1 46.2 49.9 31.7 51.9 63.6 24.1 41.6 54.7 46.2 26.0 20.6 50.9 55.0 45.4 65.6 105.0 27.4 36.3 24.1 47.4 42.0 57.8 49.5 55.7 39.6 143.1 93.3 65.0 71.1 26.3 36.0 47.8 72.6 27.3 50.1 81.1 42.4 75.9 44.4 26.8 39.8 46.6 20.7 47.8 47.8 69.1 398.1 24.3 55.8 136.0 79.2 36.2 28.5 22.4 25.0 25.7 43.7 20.3 104.2 112.2 91.2 26.2 59.5 44.8 51.1 31.3 32.1 58.3 27.9 20.7 251.1 65.4 60.6 35.0 37.7 71.1 64.8 79.9 27.9 22.1 21.6 33.8 19.4 48.9 7.1 28.3 8.9 14.6 6.9 5.3 12.7 10.8 10.9 5.9 355.0 10.0 33.3 18.9 12.5 11.5 42.6 63.3 75.4 60.7 49.5 57.5 64.0 63.0 54.6 46.2 63.6 50.9 430.3 41.7 18.6 55.8 69.4 29.3 23.5 22.5 37.0 31.5 86.5 37.8 17.6 15.7 28.9 27.6 18.8 10.8 77.5 20.3 99.7 18.0 242.6 114.8 46.7 205.9 19.7 86.5 33.0 20.7 10.8 34.0 35.2 240.5 34.7 104.3 286.3 11.1 51.6 37.0 54.6 14.0 61.1 127.2 48.1 740.3 26.4 115.1 35.6 62.8 76.1 31.4 34.0 23.1 44.4 41.8 15.2 17.3 269.1 39.5 9.6 24.8 69.5 17.2 39.5 36.4 36.3 45.1 42.5 25.1 30.4 13.3 51.6 64.3 11.5 39.1 SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 14.7;Endothelial cells: 51.8;Hepatic stellate cells: 33.9;Macrophages: 10.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 8.3;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.3;T-cells: 8.8" "Group enriched" "Detected in some" 38 "EFO-21: 36.0;HEL: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" 11.3 2.3 0.2 11.9 0.6 2.2 10.6 0.0 0.6 8.9 3.7 3.3 5.1 6.4 4.1 5.1 6.7 9.5 6.7 0.3 0.0 5.6 2.5 12.6 7.0 0.2 0.2 1.8 1.2 3.1 2.2 6.3 0.2 6.1 4.1 0.0 2.7 5.7 1.0 3.6 4.8 14.2 0.1 1.0 2.8 0.7 0.7 2.6 4.0 1.8 12.6 14.4 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.4 0.6 0.0 0.2 0.0 1.1 0.5 0.2 0.0 0.1 0.2 0.1 2.1 0.3 0.0 0.1 8.8 7.8 0.2 0.6 0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.1 0.7 0.2 14.7 0.0 3.6 0.3 0.4 3.7 0.1 0.0 0.6 0.0 0.2 0.1 1.9 1.5 0.0 1.8 0.0 2.6 0.1 0.0 0.0 0.0 2.0 0.1 0.1 51.8 0.0 5.2 0.5 0.2 0.0 1.5 0.0 0.0 0.0 0.0 33.9 0.4 0.2 0.0 0.2 0.0 0.0 1.5 3.6 0.1 0.3 10.1 3.6 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.1 3.4 4.1 0.5 0.0 0.0 0.3 SEMA6B "SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ" ENSG00000167680 "Semaphorin 6B" Q9H3T3 19 4542593-4581776 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Adipocytes: 43.6;Alveolar cells type 1: 28.9;Alveolar cells type 2: 44.6;Endothelial cells: 40.1;Excitatory neurons: 30.6;granulocytes: 29.7;Hepatic stellate cells: 37.5;Inhibitory neurons: 30.3;Macrophages: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 124.5;HMC-1: 198.1;HUVEC TERT2: 83.8;TIME: 107.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025157, HPA055778, HPA058523" Enhanced NA NA 1100000 "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB025157: , HPA055778: AB_2682916, HPA058523: AB_2683741" "unprognostic (4.03e-1)" "unprognostic (9.69e-3)" "unprognostic (6.38e-3)" "unprognostic (2.15e-1)" "unprognostic (1.15e-1)" "unprognostic (7.94e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (6.61e-2)" "unprognostic (1.90e-1)" "unprognostic (4.21e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.26e-1)" "unprognostic (1.81e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (9.55e-2)" 25.6 19.7 44.0 11.0 30.7 7.8 17.1 0.6 72.3 8.7 0.0 6.6 4.0 10.6 0.4 3.6 8.8 5.8 20.2 65.2 12.4 13.3 2.9 10.7 1.2 13.5 11.0 3.3 4.1 9.2 7.2 8.9 1.8 7.0 1.0 1.4 3.9 1.3 6.0 4.6 7.3 6.9 0.5 31.9 6.1 1.9 30.2 0.7 9.1 4.3 0.7 10.0 6.7 17.4 7.2 25.0 2.3 21.4 0.1 1.2 0.2 0.0 0.7 2.4 0.6 0.2 2.0 0.0 23.7 0.0 3.8 4.4 6.5 0.0 0.9 0.1 1.0 0.0 0.4 124.5 0.4 0.0 198.1 7.5 0.1 0.2 0.2 24.9 83.8 0.1 1.6 0.3 0.7 6.5 0.0 0.0 26.8 1.7 0.3 0.4 46.8 0.6 1.7 0.1 17.7 1.7 0.1 1.7 11.5 1.8 2.7 1.1 107.8 3.1 34.7 0.5 18.6 1.3 0.0 0.4 0.8 1.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 30.7 0.6 72.3 65.2 12.4 13.5 11.0 1.8 0.5 30.2 17.4 43.6 28.9 44.6 2.6 2.3 4.7 1.5 0.5 0.0 9.0 2.1 1.9 1.9 1.5 19.3 1.8 4.2 0.6 2.3 0.2 0.0 1.1 1.1 1.1 2.5 40.1 0.0 8.4 30.6 0.2 0.6 8.2 0.0 2.0 29.7 0.5 37.5 6.0 3.3 18.5 30.3 0.1 0.0 6.1 18.1 0.4 0.6 35.2 7.2 7.5 1.4 2.0 1.0 19.1 1.4 0.2 0.1 0.7 1.1 1.2 0.0 0.4 17.7 4.1 0.0 8.8 1.8 2.0 2.2 0.0 5.1 0.3 5.4 1.6 0.1 0.9 SGCG "A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE" ENSG00000102683 "Sarcoglycan gamma" Q13326 13 23180979-23325162 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 118.8;skeletal muscle: 158.0;tongue: 144.1" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 134.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 66.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA007476 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA007476: AB_1079946" "unprognostic (5.19e-2)" "unprognostic (8.28e-2)" "unprognostic (5.15e-3)" "unprognostic (1.64e-4)" "unprognostic (3.00e-3)" "unprognostic (3.61e-2)" "unprognostic (8.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.29e-1)" "unprognostic (4.49e-1)" "unprognostic (6.05e-2)" "unprognostic (2.23e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (2.98e-3)" "unprognostic (1.07e-1)" 14.3 0.6 0.0 0.1 0.1 0.0 2.2 0.0 1.9 0.4 0.0 1.1 0.1 0.1 8.0 3.3 1.1 0.8 118.8 0.1 0.0 0.3 0.0 4.8 0.0 0.3 0.0 0.2 0.1 2.1 0.3 0.0 0.2 3.2 0.6 0.3 4.3 0.4 158.0 3.4 0.6 0.1 0.0 0.1 0.9 1.5 0.2 0.1 0.1 144.1 0.1 3.0 1.4 0.4 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 66.6 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.2 0.0 0.2 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.3 0.0 0.2 0.0 0.2 0.4 0.2 0.0 0.0 0.3 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 1.3 0.0 0.0 12.5 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 1.6 0.0 0.0 0.0 3.4 3.0 7.5 0.2 5.4 1.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 1.2 3.8 13.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 SGK2 ENSG00000101049 "Serum/glucocorticoid regulated kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.5;kidney: 53.6;liver: 63.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.5;Distal tubular cells: 76.3;Hepatocytes: 32.8;Paneth cells: 21.7;Proximal enterocytes: 23.8;Proximal tubular cells: 25.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 20.5;CAPAN-2: 14.2;Hep G2: 18.7;OE19: 61.7;RPTEC TERT1: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA008859: AB_2668159, HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favorable (5.65e-4)" 23.5 1.4 4.9 1.5 14.8 0.5 6.1 12.6 10.5 3.5 0.7 37.7 31.6 1.8 33.8 1.0 3.7 10.0 1.2 6.0 7.7 53.6 63.2 1.0 0.2 18.1 13.3 6.6 16.2 0.5 3.0 0.8 14.3 2.6 40.5 5.6 1.8 2.9 0.4 6.2 20.1 1.6 11.8 1.1 22.8 1.8 13.3 0.3 1.7 0.4 0.3 4.2 3.0 24.5 0.0 20.5 0.3 0.1 0.3 0.0 0.1 0.2 0.0 0.2 0.0 0.6 14.2 0.1 8.7 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.4 0.0 18.7 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.1 0.1 0.5 0.1 61.7 0.0 0.1 0.1 0.0 25.4 4.2 0.2 1.0 0.0 1.2 0.1 0.4 0.0 0.1 0.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 14.8 12.6 10.5 6.0 7.7 18.1 13.3 14.3 11.8 13.3 24.5 0.3 0.0 0.0 4.9 0.2 0.1 0.1 0.2 0.0 0.8 0.3 0.8 4.9 8.6 0.0 11.0 0.0 5.1 0.0 76.5 76.3 6.8 0.3 0.9 0.5 0.6 1.8 0.0 0.7 6.3 1.3 0.4 11.2 2.4 0.0 0.7 0.7 32.8 0.7 6.7 1.3 4.1 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 3.5 20.7 2.5 21.7 0.4 0.0 0.1 23.8 25.5 0.2 0.8 0.0 0.2 0.4 0.1 0.1 0.0 0.1 17.1 0.2 0.0 7.7 0.3 SHISA3 hShisa3 ENSG00000178343 "Shisa family member 3" A0PJX4 4 42397488-42402487 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.3;heart muscle: 15.5;kidney: 21.4" "Group enriched" "Detected in some" 7 "Distal tubular cells: 43.0;Fibroblasts: 19.4;Hepatic stellate cells: 55.0" "Cancer enhanced" "Detected in many" "lung cancer: 7.6;renal cancer: 7.8" "Group enriched" "Detected in all" 4 "midbrain: 13.3;thalamus: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AN3-CA: 219.6;PC-3: 130.4" "Region enriched" "Detected in many" 23 "olfactory bulb: 51.7" "Region enriched" "Detected in many" 8 "spinal cord: 21.4" HPA054754 Approved "Lipid droplets,Cytosol" NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Lipid droplets" "HPA054754: AB_2682593" "unprognostic (9.04e-3)" "unprognostic (3.47e-3)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" "unprognostic (1.26e-1)" "unprognostic (6.78e-3)" "unprognostic (1.26e-2)" "unprognostic (2.86e-1)" "unprognostic (3.04e-1)" "unprognostic (1.37e-3)" "unprognostic (3.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "unprognostic (5.32e-2)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.99e-3)" 4.1 1.8 1.8 1.8 1.6 0.0 2.3 1.1 1.6 0.7 1.2 6.2 2.2 0.2 0.3 1.7 0.5 1.0 15.5 1.0 2.2 21.4 0.6 5.7 7.0 1.7 13.3 0.3 0.2 0.2 0.6 0.0 2.6 0.8 3.0 0.1 0.6 1.0 1.6 0.5 10.4 4.3 1.4 0.4 2.9 0.6 10.1 0.1 5.0 1.4 0.8 3.5 1.3 1.2 0.0 0.0 0.0 219.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 23.7 0.1 0.0 0.0 23.3 0.0 0.0 0.0 2.6 0.0 0.1 0.0 6.6 0.0 0.8 0.4 0.0 0.0 0.0 0.0 5.2 0.3 0.0 0.0 0.0 0.0 1.2 0.0 10.1 0.0 130.4 0.2 0.0 0.0 9.0 0.0 0.1 0.3 0.0 0.0 0.0 8.1 0.1 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.6 1.1 1.6 1.0 2.2 1.7 13.3 2.6 1.4 10.1 1.2 4.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 3.7 0.0 0.0 0.1 0.1 43.0 0.0 0.0 0.1 2.5 3.7 0.0 5.3 0.0 0.0 0.0 19.4 0.5 0.1 0.0 1.1 55.0 0.2 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.0 3.4 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 2.4 0.0 0.1 0.0 0.2 1.4 0.5 0.4 0.1 0.0 0.0 0.0 2.4 0.1 0.0 SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 398.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 307.7;Proximal tubular cells: 435.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023314, HPA078682" Enhanced Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA023314: AB_1856830, HPA078682: " "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favorable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favorable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" 37.5 9.4 8.1 4.0 9.4 9.5 36.3 12.6 9.5 13.6 7.1 17.5 13.8 7.6 4.9 59.2 13.1 7.7 5.7 8.8 8.5 168.5 398.7 10.3 9.0 10.8 9.3 11.7 8.8 85.7 4.1 7.7 10.7 10.1 6.1 3.1 30.0 10.0 18.8 22.6 24.4 3.7 8.0 21.7 13.3 12.8 9.4 21.1 23.5 18.6 17.6 11.5 19.3 16.0 39.6 28.9 5.5 34.5 29.9 15.8 63.0 11.3 10.3 30.8 31.2 22.1 22.5 26.8 27.8 3.6 16.4 18.8 32.4 39.7 24.3 17.3 30.6 13.0 39.9 21.6 7.2 4.4 11.0 21.1 13.6 23.1 7.2 10.9 9.7 32.3 10.0 10.9 11.3 12.4 46.0 13.9 17.4 43.6 5.1 29.7 48.5 34.7 69.3 17.0 24.0 5.3 82.7 14.9 21.4 50.2 64.5 19.4 2.6 5.7 14.0 71.4 17.6 10.7 20.5 7.1 10.3 12.7 16.5 10.2 4.7 5.2 5.3 5.9 8.1 4.4 6.6 5.5 3.5 3.7 6.8 6.4 0.2 8.5 5.2 1.1 11.2 4.3 8.1 9.4 12.6 9.5 8.8 8.5 10.8 9.3 10.7 8.0 9.4 16.0 11.2 12.8 31.0 3.3 10.4 10.3 21.7 16.5 18.8 3.1 22.7 13.8 2.7 42.9 11.2 36.8 4.2 23.7 5.2 8.9 82.2 13.7 10.9 6.2 1.9 7.4 1.2 28.0 5.2 7.7 76.1 8.0 9.2 10.1 8.2 9.9 13.6 307.7 39.6 0.0 4.8 12.9 4.1 36.8 3.5 5.5 5.9 17.2 12.4 9.4 4.4 33.8 5.2 2.0 11.4 5.3 9.7 3.0 20.3 5.9 53.7 435.7 3.5 4.2 19.7 8.1 4.4 30.0 21.4 35.4 10.5 8.5 10.1 4.9 32.2 10.9 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 47.8;salivary gland: 51.1;skeletal muscle: 119.4;tongue: 46.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.7;Basal respiratory cells: 30.8;Club cells: 33.9;Ionocytes: 30.5;Prostatic glandular cells: 27.4;Respiratory ciliated cells: 67.1;Skeletal myocytes: 77.3;Spermatogonia: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 36.3;LHCN-M2: 142.2;RH-30: 71.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "CAB058690: AB_2665581, HPA001893: AB_1079991" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (5.09e-2)" "prognostic unfavorable (8.92e-6)" "unprognostic (1.33e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-3)" "prognostic favorable (3.94e-4)" "unprognostic (1.40e-1)" "unprognostic (9.15e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (3.06e-8)" "unprognostic (8.61e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" 5.5 0.4 0.3 0.0 0.5 0.0 1.9 0.5 1.2 15.2 1.0 0.0 0.0 0.0 0.4 1.1 0.8 0.5 0.0 0.3 0.3 0.0 0.0 1.5 0.5 0.3 0.4 0.2 0.3 47.8 19.8 0.0 0.4 13.2 0.0 0.0 51.1 0.2 119.4 0.3 0.0 0.0 0.3 0.0 0.4 1.7 0.5 9.7 1.9 46.3 0.2 1.6 0.8 0.4 15.2 3.5 0.6 28.1 17.0 20.6 0.4 4.1 10.6 4.9 4.0 0.0 8.2 0.0 2.2 0.6 2.1 4.4 10.3 6.4 2.1 0.0 17.1 2.0 1.9 6.8 0.0 0.0 0.2 15.6 4.9 2.3 0.7 36.3 0.3 1.6 5.8 0.0 142.2 2.8 0.0 0.5 0.0 0.0 8.9 0.0 71.9 0.0 5.9 16.3 2.5 0.3 5.0 0.3 6.1 0.5 3.3 0.4 13.9 6.7 5.4 7.9 6.5 0.5 0.1 0.0 1.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.2 0.3 0.3 0.3 0.4 0.4 0.3 0.5 0.4 0.8 3.2 1.5 0.0 0.0 0.1 30.7 30.8 0.6 0.0 1.0 0.8 0.9 0.0 33.9 1.8 0.0 0.2 0.0 0.1 1.9 0.0 0.2 1.1 0.1 1.6 0.0 0.0 0.0 0.8 0.4 5.7 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.5 0.0 0.0 0.6 0.0 0.3 0.0 1.9 0.0 0.8 0.0 1.0 0.1 0.2 0.0 1.2 0.0 27.4 0.0 0.1 67.1 0.2 0.0 77.3 5.1 0.0 25.0 0.1 0.1 0.3 0.1 0.1 0.0 18.3 SLC15A5 ENSG00000188991 "Solute carrier family 15 member 5" A6NIM6 12 16188485-16277685 "Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Astrocytes: 2.0;Early spermatids: 4.2;Excitatory neurons: 1.1;Late spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041638 Uncertain NA NA "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA041638: AB_2677590" "unprognostic (3.68e-3)" "unprognostic (1.64e-1)" "unprognostic (4.89e-6)" "unprognostic (1.34e-1)" "unprognostic (1.72e-3)" 0.2 0.0 0.4 0.0 0.4 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.7;breast: 28.4;placenta: 24.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 65.4;Syncytiotrophoblasts: 160.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.9;BEWO: 6.2;CACO-2: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" 46.7 0.6 5.0 1.9 3.3 1.2 28.4 4.7 4.3 0.5 1.0 2.6 9.1 0.5 0.1 0.7 0.5 5.7 0.7 3.4 4.4 2.2 13.8 4.1 0.8 5.2 4.2 0.9 1.7 0.1 0.1 24.1 5.4 0.3 1.8 2.2 1.1 0.1 0.9 1.6 5.6 0.4 4.4 0.5 0.5 0.5 5.7 0.2 0.4 0.8 0.4 1.0 0.4 4.0 0.3 0.9 0.2 0.8 13.9 0.3 6.2 0.1 0.2 0.2 0.6 20.2 0.4 0.2 0.1 0.1 4.6 0.4 0.6 0.5 0.8 0.0 1.0 0.1 1.1 0.8 1.8 0.2 0.1 3.4 0.4 0.1 0.8 0.3 0.0 0.3 0.1 0.6 0.0 1.6 0.1 0.5 3.0 0.7 0.1 0.3 0.1 0.2 0.2 0.2 0.9 0.1 0.3 1.9 0.5 2.6 0.2 0.2 0.6 0.4 0.4 4.1 0.4 0.1 0.1 0.6 1.4 0.2 0.5 6.8 0.8 1.0 0.4 0.6 0.3 0.8 0.4 0.4 0.2 1.3 0.5 0.5 3.3 2.2 0.7 1.0 0.2 0.3 5.0 3.3 4.7 4.3 3.4 4.4 5.2 4.2 5.4 4.4 5.7 4.0 0.2 9.6 5.1 2.3 0.0 0.0 0.5 0.0 0.6 5.3 0.2 0.1 0.4 5.7 0.0 1.8 0.0 65.4 0.1 5.7 1.9 4.4 0.3 0.1 0.0 2.6 1.2 0.0 0.4 0.0 7.4 3.2 0.0 0.1 0.0 0.3 0.0 13.1 5.1 0.0 0.9 1.6 0.0 0.6 0.0 0.7 0.3 0.9 0.0 25.3 0.0 0.8 0.0 4.5 0.3 0.4 1.0 0.0 0.1 0.4 9.3 3.0 0.0 0.2 0.0 1.7 1.6 0.0 0.3 0.0 0.0 160.6 0.2 0.1 6.5 0.4 SLC22A3 "EMT, OCT3" ENSG00000146477 "Solute carrier family 22 member 3" O75751 6 160348378-160452577 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 67.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 78.9;Hepatocytes: 68.8;Leydig cells: 33.8;Pancreatic endocrine cells: 57.3;Skeletal myocytes: 29.8" "Cancer enhanced" "Detected in many" "prostate cancer: 19.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 27.6;HeLa: 38.1;Hep G2: 23.7;OE19: 12.0;RPTEC TERT1: 13.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029750 Approved Approved Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Vesicles Cytosol "HPA029750: AB_10603888" "unprognostic (8.61e-2)" "prognostic unfavorable (7.19e-5)" "unprognostic (4.14e-1)" "unprognostic (1.49e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (3.36e-2)" "unprognostic (9.74e-2)" "unprognostic (9.36e-4)" "unprognostic (1.33e-2)" "unprognostic (2.58e-2)" "unprognostic (7.28e-2)" "unprognostic (7.96e-2)" "unprognostic (5.21e-2)" "unprognostic (8.13e-4)" "prognostic unfavorable (7.26e-4)" 11.7 15.2 2.1 3.8 2.7 0.0 6.6 3.3 2.1 15.9 1.8 8.8 1.7 18.4 27.6 7.7 18.7 11.0 1.5 2.0 3.5 6.3 34.9 16.4 16.2 6.2 3.8 21.1 0.7 0.2 1.3 44.3 4.5 43.4 2.4 0.2 51.8 52.6 67.4 10.7 5.7 26.3 3.3 0.6 6.0 2.6 4.2 0.5 2.0 8.5 4.9 6.2 15.7 3.2 0.0 27.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.5 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.4 0.0 0.0 0.0 38.1 23.7 1.2 0.0 0.0 0.8 6.9 3.4 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.0 12.0 7.7 0.0 0.0 0.0 13.8 0.0 0.0 0.0 3.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.3 2.1 2.0 3.5 6.2 3.8 4.5 3.3 4.2 3.2 0.6 16.0 78.9 6.2 0.1 4.7 0.3 2.1 2.8 0.2 0.2 0.3 2.9 5.7 6.4 0.0 0.0 0.3 0.1 0.2 5.9 8.2 0.6 0.2 10.2 1.0 0.0 0.0 0.5 3.0 0.3 10.0 12.8 0.3 2.5 0.8 0.0 68.8 0.7 0.0 25.1 1.6 2.0 1.0 2.4 1.6 33.8 0.3 3.6 7.5 0.0 0.0 0.0 19.6 0.2 57.3 0.1 24.5 0.1 6.1 2.1 2.9 0.8 0.1 0.0 29.8 12.3 0.3 0.2 3.7 6.7 0.4 1.2 0.0 2.8 0.8 SLC25A1 "CTP, SLC20A3" ENSG00000100075 "Solute carrier family 25 member 1" P53007 22 19175581-19178739 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 197.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 221.1;Proximal enterocytes: 304.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 101.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.12e-1)" "unprognostic (3.98e-1)" "unprognostic (8.17e-2)" "unprognostic (1.13e-1)" "unprognostic (9.39e-2)" "unprognostic (2.61e-2)" "unprognostic (3.11e-2)" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (5.74e-2)" "unprognostic (3.90e-2)" "unprognostic (5.72e-2)" "unprognostic (4.52e-2)" "unprognostic (1.84e-1)" "unprognostic (3.46e-2)" "unprognostic (6.14e-2)" "unprognostic (9.03e-2)" 113.3 76.3 45.8 22.3 46.9 14.2 90.3 49.5 58.6 43.5 47.6 63.9 114.1 40.0 16.2 59.2 34.7 21.5 27.3 41.5 65.8 86.8 197.7 33.6 21.4 61.0 58.3 43.6 54.8 33.1 39.3 27.4 73.0 53.9 33.9 5.6 39.5 30.0 17.3 49.1 92.4 21.0 49.4 31.4 52.9 36.3 51.8 16.3 46.1 7.7 25.5 43.9 40.8 55.2 111.9 114.3 85.9 73.6 209.1 102.5 91.2 77.5 96.9 65.7 90.4 136.4 77.2 66.9 38.8 110.5 70.5 95.4 82.9 138.1 37.2 59.6 164.1 35.5 97.7 278.4 148.2 67.3 107.5 145.1 81.7 75.7 58.4 73.3 62.8 53.4 184.6 61.9 74.7 288.1 37.0 80.8 57.5 173.5 70.0 70.4 44.6 29.9 196.2 135.8 55.5 71.2 83.1 163.0 48.6 52.6 122.6 171.7 63.6 80.3 69.3 62.0 53.2 78.2 39.9 35.4 82.5 31.5 41.4 11.6 15.7 101.9 16.6 17.9 10.6 33.3 18.7 18.2 13.7 43.5 16.7 14.3 8.1 13.7 23.8 10.5 19.6 10.6 45.8 46.9 49.5 58.6 41.5 65.8 61.0 58.3 73.0 49.4 51.8 55.2 18.5 9.6 18.9 10.7 35.0 22.0 27.2 21.6 31.9 7.8 44.2 41.9 7.2 38.6 17.0 33.1 2.1 135.6 18.4 178.6 50.9 33.5 30.5 41.4 37.0 16.8 41.0 21.7 5.2 45.6 139.5 27.1 50.4 83.7 2.5 67.5 21.4 221.1 47.5 13.5 6.1 107.3 28.5 30.5 18.2 98.8 28.9 32.6 28.4 2.8 29.6 27.7 16.5 3.0 10.1 39.7 128.1 29.3 38.7 28.7 304.3 127.3 11.1 4.2 13.1 14.5 37.8 15.3 29.5 60.5 30.4 127.7 24.6 55.7 108.3 30.4 SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA036243: AB_2675019, HPA044580: AB_10962723" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.23e-2)" "unprognostic (9.13e-3)" "unprognostic (1.92e-1)" "unprognostic (4.13e-2)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (8.37e-3)" "unprognostic (2.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.06e-2)" "unprognostic (1.44e-3)" 10.3 3.6 5.1 2.1 5.3 3.7 4.1 7.1 7.9 2.1 0.0 3.2 3.8 3.5 3.2 2.6 2.1 2.3 2.8 5.0 5.6 5.8 11.4 3.1 2.7 2.7 3.5 2.3 5.1 3.5 2.6 2.8 3.4 8.2 2.8 4.7 4.5 2.8 4.9 3.0 3.8 2.6 2.2 2.4 4.5 1.5 7.0 2.0 3.5 2.3 2.0 2.7 2.1 6.1 2.8 1.1 3.2 4.4 4.2 5.0 3.4 3.8 4.2 2.4 2.6 6.6 1.9 3.0 2.7 7.6 1.3 1.6 10.2 1.9 6.1 2.2 6.3 1.6 3.5 2.9 5.1 5.2 3.4 4.3 4.9 4.6 6.4 3.6 2.0 2.6 1.8 4.8 5.2 2.6 2.9 3.7 0.7 0.8 14.8 1.6 2.3 1.0 6.8 9.2 2.2 1.8 5.4 5.2 4.4 2.2 2.9 2.1 8.9 3.6 4.8 6.1 4.5 4.9 2.8 4.9 3.5 4.2 1.6 1.4 0.7 0.7 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.8 0.4 0.6 1.3 0.6 0.4 0.8 0.4 0.3 5.1 5.3 7.1 7.9 5.0 5.6 2.7 3.5 3.4 2.2 7.0 6.1 9.6 44.8 20.7 23.5 9.9 6.4 6.3 4.9 4.6 19.2 11.0 6.7 10.4 12.8 7.4 12.9 39.6 19.0 12.4 12.9 11.7 8.1 9.9 9.6 9.3 7.8 15.0 9.9 44.0 19.2 32.3 8.8 20.9 14.1 8.2 6.1 13.9 37.7 10.6 20.2 53.7 9.4 8.2 10.3 6.5 13.0 3.1 7.9 1.8 13.1 8.2 9.5 15.5 29.7 48.0 14.4 7.8 7.9 16.4 13.5 17.7 21.4 9.9 31.2 0.0 13.4 11.3 4.5 2.5 10.5 6.8 59.8 9.4 9.4 9.0 10.6 SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 143.8;choroid plexus: 90.7;liver: 111.5" "Group enriched" "Detected in many" 4 "Astrocytes: 195.2;Hepatocytes: 72.8" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;BEWO: 8.5" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" 14.4 1.0 130.1 0.3 132.1 0.1 7.2 116.5 141.1 2.5 90.7 2.9 0.3 2.9 0.2 0.3 3.8 0.9 2.8 119.4 123.3 1.9 111.5 1.2 0.3 121.7 129.2 1.2 1.1 0.2 1.5 0.1 112.5 7.8 0.1 1.9 0.5 0.4 6.2 1.2 1.9 0.5 106.5 4.8 1.5 4.2 143.8 0.3 0.6 4.0 0.1 0.8 1.4 110.7 0.3 0.6 2.2 0.4 3.8 0.0 8.5 0.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.5 0.7 0.0 0.0 0.0 0.3 1.0 0.3 0.3 0.5 1.5 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.3 0.0 0.4 0.1 0.5 2.0 0.9 1.4 2.9 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.4 0.7 1.6 2.5 1.0 0.1 0.1 0.3 0.2 0.3 0.9 1.2 0.0 1.8 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.1 132.1 116.5 141.1 119.4 123.3 121.7 129.2 112.5 106.5 143.8 110.7 1.0 28.9 10.3 195.2 0.3 0.0 0.3 0.1 0.6 0.6 0.3 0.0 1.5 5.7 7.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.6 0.4 0.9 1.7 0.0 10.7 2.0 0.0 0.3 4.7 0.0 0.7 6.3 8.5 3.6 72.8 0.3 0.0 3.0 0.3 0.0 4.1 0.3 0.6 0.9 3.9 0.0 10.3 0.1 2.2 1.0 13.0 11.5 0.0 0.0 2.6 0.1 4.3 0.1 0.8 15.8 3.4 0.0 2.7 2.5 4.8 5.9 0.0 0.1 1.8 2.6 2.6 0.0 0.2 SLC25A20 "CAC, CACT" ENSG00000178537 "Solute carrier family 25 member 20" O43772 3 48856926-48898904 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.2;Hepatocytes: 64.2;Proximal enterocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 96.1;RPMI-8226: 138.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016862, HPA029863" Approved Approved Mitochondria,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Mitochondria, Cytosol" "HPA016862: AB_1857028, HPA029863: AB_10602893" "unprognostic (1.02e-1)" "unprognostic (1.84e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-2)" "unprognostic (5.18e-2)" "unprognostic (3.97e-2)" "unprognostic (1.03e-1)" "unprognostic (5.96e-3)" "unprognostic (4.06e-1)" "unprognostic (1.73e-1)" "unprognostic (1.36e-2)" "unprognostic (2.51e-1)" "unprognostic (3.71e-3)" "unprognostic (3.34e-1)" "unprognostic (5.12e-1)" "unprognostic (4.22e-2)" "unprognostic (3.49e-2)" 20.7 29.9 16.3 11.9 18.2 10.7 17.9 18.6 16.4 8.3 15.3 26.5 65.6 10.4 4.6 9.1 12.8 15.7 62.8 15.5 17.9 25.6 148.3 15.6 14.6 17.7 17.4 5.9 30.4 17.3 11.6 7.3 17.8 11.7 23.5 4.5 19.9 9.0 66.5 10.4 52.7 15.1 17.4 20.6 21.0 9.1 17.5 17.3 11.4 61.1 16.1 11.3 8.4 18.4 4.1 12.8 9.7 13.8 30.1 11.8 1.9 22.3 11.8 15.2 15.8 16.3 19.1 19.0 15.6 35.1 18.7 4.1 24.5 9.8 11.6 47.9 11.8 26.4 19.2 20.4 14.0 27.8 48.1 14.9 11.2 20.6 3.8 6.1 20.2 28.1 24.1 96.1 20.2 10.9 30.4 13.7 5.1 22.9 27.6 10.6 5.9 138.4 16.4 10.1 3.9 13.6 20.7 0.2 11.4 13.6 30.5 12.9 16.6 17.2 3.2 25.5 16.4 35.6 27.0 21.8 24.5 19.5 23.3 60.8 101.1 215.2 97.4 79.7 62.2 36.8 53.1 71.2 97.5 33.0 41.2 69.1 48.6 64.6 83.7 120.5 60.7 112.3 16.3 18.2 18.6 16.4 15.5 17.9 17.7 17.4 17.8 17.4 17.5 18.4 7.5 6.4 2.7 13.1 7.0 1.8 2.5 4.6 3.4 1.1 4.0 3.6 42.2 4.3 4.4 0.0 6.2 2.3 13.6 28.4 3.9 3.5 1.3 2.3 4.6 5.5 7.3 16.4 2.2 4.3 2.3 6.1 9.2 2.1 1.3 3.8 7.5 64.2 16.9 0.0 3.8 12.7 2.0 13.4 4.5 1.8 10.5 10.0 1.8 1.0 31.3 2.9 32.0 1.0 6.0 3.7 16.4 12.4 12.6 3.9 51.8 16.7 5.9 1.3 0.0 5.4 5.3 8.3 7.1 4.1 1.3 1.2 14.4 27.7 16.6 2.9 SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 93.6;Late spermatids: 169.6;Spermatocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (5.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (6.87e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-3)" "unprognostic (1.26e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.52e-4)" "unprognostic (8.27e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (2.08e-2)" 9.0 3.1 3.1 5.0 3.5 12.0 4.1 3.4 4.4 5.4 2.3 4.5 7.5 4.1 4.7 5.6 3.4 5.0 4.5 3.7 4.1 6.3 3.1 5.2 5.7 3.4 3.3 3.8 5.9 8.3 4.1 4.7 4.0 3.5 4.1 4.8 4.7 3.7 6.1 5.7 6.0 5.8 2.6 5.7 4.3 8.0 3.1 5.6 4.6 7.4 6.5 4.3 3.5 4.4 12.4 10.1 7.3 11.6 34.4 15.2 7.4 10.6 10.7 8.8 12.6 13.0 5.2 26.2 5.9 24.2 12.5 6.1 19.6 14.5 16.5 18.0 6.1 8.0 27.5 18.0 19.1 12.5 11.1 15.3 16.7 13.4 16.6 13.6 16.1 24.4 17.9 20.2 19.1 7.3 15.2 3.2 9.2 12.7 7.1 10.6 9.9 16.1 8.7 8.9 15.2 10.0 8.3 10.1 6.0 12.2 5.4 13.7 17.3 14.7 17.4 7.2 12.8 7.7 17.5 17.5 19.4 9.3 12.3 16.7 1.5 2.8 1.6 3.1 2.7 2.6 1.7 2.3 1.1 1.5 1.6 1.8 1.3 1.9 1.3 0.5 2.7 0.9 3.1 3.5 3.4 4.4 3.7 4.1 3.4 3.3 4.0 2.6 3.1 4.4 4.3 9.6 1.1 13.4 9.3 4.7 5.8 7.6 8.6 4.0 5.1 3.8 6.3 5.7 4.6 1.8 4.2 3.7 7.6 3.8 17.6 9.5 93.6 2.5 5.3 4.3 3.6 6.9 22.0 7.2 14.1 5.2 8.2 5.1 3.8 3.4 3.9 3.6 11.7 1.7 21.3 5.8 0.0 5.7 4.7 169.6 3.7 8.8 1.8 19.7 8.4 5.3 3.1 16.1 22.1 7.3 7.2 4.1 14.3 3.8 17.4 16.8 2.2 3.7 0.0 4.3 4.5 44.0 10.2 11.7 5.8 4.0 6.5 4.8 3.6 3.8 SLC29A4 "ENT4, FLJ34923" ENSG00000164638 "Solute carrier family 29 member 4" Q7RTT9 7 5274369-5306912 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 43.3;choroid plexus: 55.5" "Group enriched" "Detected in many" 5 "Enteroendocrine cells: 103.2;Horizontal cells: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 49.2;SH-SY5Y: 70.7;U-2 OS: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052829 Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Microtubules, Cytokinetic bridge" "HPA052829: AB_2681967" "unprognostic (6.04e-2)" "unprognostic (1.22e-2)" "unprognostic (8.49e-5)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" "unprognostic (4.24e-2)" "unprognostic (9.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.55e-2)" "unprognostic (5.73e-2)" "prognostic favorable (4.52e-4)" "unprognostic (2.06e-1)" "unprognostic (3.02e-2)" "unprognostic (3.24e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-3)" "unprognostic (6.60e-2)" 43.3 8.2 13.2 0.7 16.2 0.6 13.3 16.0 20.0 4.9 55.5 3.1 4.6 5.4 5.0 1.1 4.0 1.6 3.7 26.3 28.5 7.9 9.2 0.9 0.2 23.2 26.1 2.2 15.4 1.7 3.6 0.6 23.6 5.8 1.8 4.1 1.3 0.7 2.6 3.0 5.5 1.8 17.2 1.6 6.5 2.6 30.0 0.3 9.7 0.4 0.1 2.4 2.0 7.4 0.0 21.7 12.6 49.2 0.6 0.2 2.4 1.8 0.1 1.6 0.9 12.3 0.4 0.0 2.4 1.9 8.1 0.3 4.8 0.4 0.5 0.1 2.8 0.2 0.7 18.3 3.8 0.2 3.0 1.5 16.2 0.3 0.9 2.9 1.5 4.5 3.6 0.1 1.2 10.8 2.0 0.9 16.0 1.5 1.3 8.3 2.1 1.9 3.2 0.5 8.4 70.7 1.3 4.4 0.9 10.7 5.5 5.9 0.7 17.3 23.4 1.6 0.5 1.1 0.0 0.1 2.2 0.7 8.0 0.8 0.3 0.2 0.2 0.1 0.4 0.2 0.1 0.2 0.1 0.4 0.2 0.2 1.3 1.6 0.1 0.3 0.1 0.1 13.2 16.2 16.0 20.0 26.3 28.5 23.2 26.1 23.6 17.2 30.0 7.4 0.5 3.2 0.5 8.8 0.0 0.1 0.2 0.1 0.0 6.9 0.7 0.6 2.5 0.0 0.2 0.0 16.7 0.3 0.2 6.3 0.0 5.3 0.1 3.3 3.0 0.6 103.2 0.0 2.4 0.2 0.4 2.2 2.0 0.7 0.0 25.7 0.0 1.0 0.4 168.2 14.3 4.4 0.0 0.3 0.7 0.7 0.3 0.3 0.0 0.0 0.1 4.8 0.0 4.0 0.6 1.4 0.5 0.4 0.1 2.3 0.8 0.2 1.4 1.6 0.0 0.5 2.2 0.4 4.2 0.1 0.3 0.3 0.3 1.7 1.0 0.2 SLC2A4 GLUT4 ENSG00000181856 "Solute carrier family 2 member 4" P14672 17 7281718-7288257 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 98.8;skeletal muscle: 223.6" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 135.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "Hep G2: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016544 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016544: AB_629533" "unprognostic (2.53e-1)" "unprognostic (7.40e-3)" "unprognostic (2.27e-1)" "unprognostic (8.12e-4)" "unprognostic (2.40e-1)" "unprognostic (6.28e-2)" "unprognostic (1.70e-2)" "unprognostic (1.66e-2)" "unprognostic (1.35e-1)" "unprognostic (3.83e-2)" "unprognostic (9.66e-2)" "unprognostic (2.24e-2)" "unprognostic (1.34e-3)" "unprognostic (4.23e-2)" "unprognostic (3.10e-1)" "unprognostic (2.30e-2)" "unprognostic (2.07e-2)" 16.9 5.2 1.4 0.2 1.7 1.1 11.2 0.9 1.5 9.2 0.9 53.1 0.8 9.3 1.2 5.9 11.3 0.7 98.8 1.3 1.1 2.6 3.7 2.1 0.2 1.0 1.5 3.2 0.8 3.4 4.4 0.6 1.2 9.9 1.1 0.4 6.3 3.3 223.6 4.1 9.7 4.3 1.0 0.3 11.7 3.3 1.3 0.1 4.5 63.2 0.0 27.0 5.6 1.1 0.0 0.0 0.4 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 1.7 0.9 1.5 1.3 1.1 1.0 1.5 1.2 1.0 1.3 1.1 1.7 0.0 0.0 1.0 0.0 1.8 0.9 0.3 2.2 0.1 1.5 1.3 135.2 0.0 0.2 0.0 0.0 0.3 0.0 1.0 7.9 0.1 16.6 0.2 0.1 3.7 0.0 10.7 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.3 1.8 2.8 0.1 0.0 0.0 0.8 0.0 0.3 0.3 4.8 0.0 0.1 7.2 1.0 0.0 6.0 0.0 0.0 0.0 0.1 1.2 8.6 0.0 0.8 0.8 0.3 0.4 0.4 32.9 7.0 19.8 1.7 2.2 0.5 1.1 1.0 0.1 0.5 1.0 0.7 SLC35C1 "FLJ11320, FUCT1" ENSG00000181830 "Solute carrier family 35 member C1" Q96A29 11 45804072-45813016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 84.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.6;Distal enterocytes: 54.6;Pancreatic endocrine cells: 50.6;Paneth cells: 54.0;Proximal enterocytes: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064001 Enhanced Supported "Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA064001: AB_2685171" "unprognostic (2.62e-2)" "unprognostic (5.16e-2)" "unprognostic (7.82e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (8.22e-2)" "unprognostic (9.40e-2)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "unprognostic (4.09e-2)" "unprognostic (2.73e-1)" "unprognostic (7.68e-2)" "unprognostic (1.83e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.64e-4)" "unprognostic (2.30e-2)" 28.2 7.3 6.6 10.7 6.3 2.4 19.8 7.0 7.0 9.6 6.1 19.8 24.4 8.8 2.3 41.5 7.3 12.2 9.0 6.2 7.2 7.0 84.5 10.2 6.6 8.2 7.9 6.3 13.4 5.6 10.4 15.0 7.7 9.9 14.3 1.6 26.1 5.9 6.8 5.1 24.1 9.9 6.5 8.4 18.5 5.2 8.8 4.5 6.6 6.9 10.0 13.8 14.9 6.3 10.3 25.8 6.3 16.3 19.9 19.8 19.5 22.1 20.1 13.3 14.4 10.7 15.2 10.4 9.9 27.3 19.4 26.0 13.4 13.6 6.5 24.8 14.5 5.9 20.4 20.6 42.6 11.4 16.2 23.8 16.3 9.2 11.1 16.2 17.6 10.3 13.3 13.8 14.4 21.8 5.9 9.0 27.5 39.9 34.6 7.2 10.5 21.5 15.1 25.4 6.0 8.6 16.6 16.3 9.5 6.6 13.7 6.0 25.7 25.0 14.7 46.1 15.6 9.8 26.9 4.9 18.5 14.4 14.2 9.7 11.6 12.5 11.0 11.9 12.3 5.0 18.0 14.7 9.6 3.7 9.3 8.0 1.8 5.6 8.7 8.2 13.0 10.1 6.6 6.3 7.0 7.0 6.2 7.2 8.2 7.9 7.7 6.5 8.8 6.3 5.5 0.0 11.2 2.6 6.2 3.6 8.9 12.7 3.4 1.9 11.1 3.0 50.6 22.8 26.7 5.5 2.1 13.8 6.4 54.6 0.0 18.4 4.9 7.3 6.7 10.6 9.6 3.6 2.0 41.9 14.0 10.5 23.4 11.4 2.5 5.2 6.8 42.2 14.7 3.3 2.1 40.6 4.1 9.3 4.8 6.0 6.5 6.3 1.8 2.8 9.5 2.8 7.2 1.0 2.1 50.6 54.0 5.7 13.6 11.8 58.0 4.7 11.4 1.1 0.0 3.6 9.7 4.0 4.3 12.7 2.4 15.3 6.5 5.7 26.4 20.1 SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 185.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.3;Cardiomyocytes: 10.8;Cytotrophoblasts: 14.3;dendritic cells: 9.6;Extravillous trophoblasts: 14.6;Hofbauer cells: 36.1;Syncytiotrophoblasts: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA051666: AB_2681567" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (6.45e-2)" "unprognostic (3.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.34e-1)" "unprognostic (1.40e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-2)" 57.1 24.4 32.1 14.4 30.4 38.3 53.4 25.3 40.0 30.3 33.5 38.0 9.7 27.4 5.6 46.5 27.0 14.5 32.4 37.0 26.9 49.0 185.4 37.4 18.1 34.5 31.2 21.6 33.8 11.5 23.8 10.3 31.9 32.2 7.5 7.2 38.9 9.9 83.9 55.5 24.5 8.5 29.1 34.4 25.6 77.0 34.3 12.3 68.4 25.9 8.9 26.3 34.2 29.2 34.8 11.7 11.9 23.0 26.0 16.6 16.0 22.4 15.1 17.6 16.6 15.6 18.5 14.6 8.5 20.4 10.3 34.8 16.2 23.8 4.7 44.3 23.8 18.2 16.7 42.6 30.9 44.2 44.5 18.6 23.2 16.2 6.2 9.0 15.3 15.8 6.9 11.6 9.2 26.6 22.1 47.6 3.9 4.7 31.5 38.7 12.4 24.6 12.0 24.4 34.8 15.7 16.9 21.3 25.6 3.1 12.7 48.0 19.4 26.8 27.2 14.3 17.2 5.8 10.0 18.8 20.5 53.2 12.1 0.3 1.7 2.0 0.6 1.7 0.4 0.8 0.7 0.3 1.9 0.6 0.9 1.1 1.2 1.0 1.6 3.5 0.8 0.8 32.1 30.4 25.3 40.0 37.0 26.9 34.5 31.2 31.9 29.1 34.3 29.2 20.3 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 14.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 14.6 4.6 0.0 0.0 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 20.8 2.0 0.0 0.0 0.0 SLC6A8 "CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.0;Distal enterocytes: 382.0;Proximal enterocytes: 235.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 155.8;AN3-CA: 151.3;SK-BR-3: 156.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" 31.6 66.6 77.2 9.0 99.4 34.5 23.9 77.8 80.0 17.5 39.9 73.5 51.3 32.4 13.0 54.6 17.3 31.3 130.4 76.8 82.1 81.4 4.5 9.2 1.9 89.0 90.5 12.4 20.0 45.6 21.4 36.2 76.9 31.3 30.5 34.7 52.3 35.9 166.6 45.9 75.9 20.7 71.3 13.1 30.8 38.5 87.6 11.9 8.2 75.5 3.0 41.2 36.5 116.6 155.8 6.7 39.5 151.3 14.7 9.9 10.2 22.2 37.7 28.7 35.5 20.1 2.1 0.2 17.0 27.9 33.6 54.3 85.3 78.0 17.0 2.7 83.3 0.6 50.6 59.7 50.0 1.2 10.1 20.9 16.5 27.3 103.3 50.7 14.9 0.9 37.3 2.4 15.7 9.3 0.8 3.6 47.0 30.9 67.0 7.6 5.2 2.1 30.8 29.5 56.0 64.2 33.8 156.8 107.9 9.8 30.9 23.9 14.1 45.2 73.1 58.2 66.5 5.2 3.0 1.8 105.5 4.5 47.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 77.2 99.4 77.8 80.0 76.8 82.1 89.0 90.5 76.9 71.3 87.6 116.6 5.9 0.0 1.9 14.0 2.7 23.2 14.3 91.1 13.1 142.0 19.6 18.4 106.9 21.5 55.6 5.5 110.5 15.3 2.8 382.0 3.9 4.6 1.5 21.4 38.9 6.5 25.9 23.4 8.2 22.2 37.7 8.8 6.1 16.1 4.5 14.4 3.9 0.9 4.9 119.5 9.9 44.2 38.7 1.9 5.7 3.7 9.0 4.1 24.9 2.8 3.2 19.0 0.0 9.0 23.7 47.5 101.1 8.2 0.8 28.3 235.8 53.3 31.3 49.3 32.9 15.6 19.0 2.9 3.9 16.9 15.6 90.8 2.9 1.5 20.7 18.6 SLC7A10 asc-1 ENSG00000130876 "Solute carrier family 7 member 10" Q9NS82 19 33208664-33225850 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 31.8;brain: 12.7;breast: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 40.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.9;HHSteC: 1.1;HSkMC: 1.6;THP-1: 3.9;U-2 OS: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041884, HPA057036" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli" "HPA041884: AB_10794494, HPA057036: AB_2683317" "unprognostic (1.85e-2)" "unprognostic (1.69e-3)" "unprognostic (2.79e-2)" "unprognostic (1.79e-6)" "unprognostic (1.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (4.98e-3)" "unprognostic (4.64e-2)" "unprognostic (1.96e-1)" "unprognostic (3.28e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-2)" "unprognostic (1.34e-3)" "unprognostic (8.91e-2)" "unprognostic (3.47e-1)" "unprognostic (2.18e-2)" 31.8 0.3 7.9 0.1 9.7 0.0 12.7 10.1 11.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.3 9.2 0.5 0.0 0.0 0.2 8.5 12.4 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.5 0.8 0.0 0.1 0.2 0.5 0.0 6.0 0.0 0.1 0.5 12.7 0.0 0.5 0.4 0.3 0.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 9.7 10.1 11.1 7.3 9.2 8.5 12.4 8.4 6.0 12.7 5.1 0.1 0.0 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 2.4 0.0 9.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.0" "Cell type enhanced" "Detected in many" "Microglial cells: 55.3;Syncytiotrophoblasts: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Plasma membrane" "HPA050713: AB_2681218" "unprognostic (6.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-2)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (1.89e-3)" "unprognostic (7.82e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.84e-4)" 35.3 8.8 1.7 15.5 1.9 8.4 26.9 6.5 3.3 5.5 17.3 8.3 3.9 5.8 11.5 4.5 8.6 4.4 18.5 3.3 2.2 5.9 2.0 10.9 18.6 1.0 1.3 2.7 3.8 2.5 9.6 18.6 1.5 6.2 11.1 5.0 7.3 5.2 75.0 10.2 12.0 7.7 1.0 10.7 6.6 5.1 2.2 37.6 16.7 26.9 21.5 6.8 4.8 1.1 22.6 22.1 16.3 16.8 46.9 27.6 42.9 24.9 18.7 36.9 30.6 97.9 16.2 43.7 19.8 33.4 10.9 33.1 32.0 32.2 39.7 9.5 22.9 23.8 47.3 31.0 7.7 28.2 20.3 19.3 26.1 27.5 13.5 11.4 25.3 21.0 35.1 7.3 20.5 11.7 36.4 19.3 12.4 14.6 8.1 45.0 10.2 36.0 12.0 19.6 23.7 13.5 75.7 20.8 6.8 13.4 30.9 13.3 38.4 24.6 19.0 20.5 32.8 16.7 33.5 50.3 15.6 20.1 17.2 3.4 3.2 2.8 4.3 1.7 5.4 6.8 6.6 4.3 3.6 6.3 11.7 6.7 6.1 7.1 1.4 16.8 3.1 1.5 1.7 1.9 6.5 3.3 3.3 2.2 1.0 1.3 1.5 1.0 2.2 1.1 8.5 41.7 18.8 12.4 18.4 19.6 9.3 8.5 13.6 6.1 5.9 4.8 19.9 2.8 4.9 18.4 37.5 25.1 23.3 7.3 0.0 3.3 5.5 10.7 16.8 12.0 2.4 2.1 39.3 4.0 2.5 12.8 4.1 3.3 4.5 1.8 6.8 1.4 14.6 10.1 40.3 10.5 4.1 8.5 12.1 18.3 5.9 9.9 10.6 55.3 10.0 1.8 14.4 13.0 10.7 5.6 5.9 3.8 16.0 8.0 2.5 0.6 10.4 2.7 0.0 10.8 7.2 17.3 10.9 6.7 21.9 47.9 23.5 4.3 7.8 2.6 SMIM3 "C5orf62, MSTP150, NID67" ENSG00000256235 "Small integral membrane protein 3" Q9BZL3 5 150778757-150796734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 161.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.5;Basal squamous epithelial cells: 80.8;granulocytes: 90.0;Macrophages: 79.3;Sertoli cells: 138.1;Smooth muscle cells: 77.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 409.9;ASC TERT1: 200.1;LHCN-M2: 193.8;U-87 MG: 291.5" "Low region specificity" "Detected in all" HPA075345 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA075345: AB_2686744" "unprognostic (2.33e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "unprognostic (9.45e-2)" "unprognostic (5.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.47e-1)" "unprognostic (3.90e-1)" "unprognostic (2.05e-2)" "unprognostic (9.71e-3)" "unprognostic (3.46e-3)" "prognostic unfavorable (1.15e-8)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.46e-3)" 161.0 36.2 20.5 25.5 20.3 89.5 71.5 20.9 26.4 21.9 42.1 26.8 13.4 16.2 22.6 16.8 30.2 25.7 36.8 20.5 22.1 34.9 12.2 30.9 11.7 23.3 21.5 25.9 33.7 26.9 15.1 46.0 23.6 27.6 19.1 20.4 14.0 24.1 15.0 12.5 23.0 28.3 20.7 25.2 21.6 4.1 23.5 17.7 21.0 15.5 8.8 29.0 18.7 19.6 13.8 4.5 7.3 60.8 409.9 200.1 15.9 52.3 114.6 19.2 77.2 21.5 35.3 0.0 3.1 55.1 12.7 10.7 12.5 11.8 28.6 0.2 3.8 20.0 2.8 9.9 72.4 19.7 130.0 167.9 23.6 54.2 25.1 122.3 6.4 46.6 5.5 0.4 193.8 10.5 28.5 27.0 3.8 10.7 12.5 15.2 1.2 0.0 20.6 10.2 1.8 4.7 7.8 1.1 16.1 8.1 25.4 120.6 10.1 84.2 15.2 65.9 27.5 0.0 0.4 0.2 291.5 75.0 10.8 68.7 41.0 72.4 20.8 17.2 12.7 1.3 14.5 14.4 19.4 0.2 14.1 12.1 42.7 13.0 16.2 57.3 2.3 38.0 20.5 20.3 20.9 26.4 20.5 22.1 23.3 21.5 23.6 20.7 23.5 19.6 53.7 6.4 8.6 2.6 3.2 0.0 85.5 0.0 80.8 0.8 12.0 16.6 9.9 7.2 2.5 7.3 0.0 8.5 22.8 4.0 13.7 6.4 0.8 1.3 11.1 25.4 4.8 8.4 1.0 31.3 5.0 53.5 2.6 1.1 90.0 1.7 13.2 1.0 45.2 0.0 2.0 36.8 0.0 34.2 0.0 0.6 14.0 79.3 0.0 16.9 30.2 62.1 11.3 5.5 0.1 18.2 1.1 36.9 3.5 15.9 3.9 8.8 0.0 1.9 138.1 72.3 77.2 0.1 0.5 20.1 0.0 8.1 28.8 3.0 7.4 40.1 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SNTA1 "LQT12, SNT1, TACIP1" ENSG00000101400 "Syntrophin alpha 1" Q13424 20 33407957-33443763 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 198.3;skeletal muscle: 307.9;tongue: 327.9" "Cell type enhanced" "Detected in many" "Astrocytes: 117.2;Cardiomyocytes: 175.1;Muller glia cells: 83.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 10.4" "Group enriched" "Detected in many" 4 "B-cells: 5.7;dendritic cells: 10.4" "Cell line enhanced" "Detected in many" "ASC diff: 66.5" "Low region specificity" "Detected in all" "CAB037059, HPA067154" Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB037059: AB_261497, HPA067154: " "unprognostic (2.25e-2)" "unprognostic (1.29e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (9.60e-6)" "unprognostic (5.68e-2)" "unprognostic (6.48e-2)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "prognostic favorable (7.08e-4)" "unprognostic (2.16e-1)" "prognostic favorable (3.72e-4)" "unprognostic (1.99e-1)" "unprognostic (8.09e-2)" "unprognostic (5.16e-2)" "unprognostic (1.48e-2)" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" 39.2 18.7 162.7 4.5 179.8 2.0 25.5 158.2 198.3 24.9 127.9 23.7 6.6 16.9 8.0 22.6 20.4 7.6 195.9 158.1 149.3 23.0 16.6 8.0 5.9 167.9 166.0 20.6 13.5 20.9 12.4 3.1 144.5 19.6 3.0 15.0 31.3 18.1 307.9 15.0 13.7 9.3 147.4 5.0 23.8 19.3 178.7 3.4 77.8 327.9 5.2 38.6 17.0 144.5 13.0 6.5 2.9 28.2 66.5 13.0 2.8 9.8 13.6 18.3 15.2 16.9 4.3 9.3 11.6 16.8 33.4 16.9 8.4 5.4 3.2 1.9 10.8 0.5 15.7 23.9 18.8 0.9 1.6 12.0 6.7 8.0 3.0 10.1 2.8 8.8 22.8 3.5 9.3 1.6 17.7 2.2 1.6 1.9 37.2 11.1 20.8 10.3 3.8 11.6 12.3 10.6 38.5 11.5 19.4 2.2 17.8 1.6 4.6 9.0 17.5 36.1 9.2 21.2 11.7 5.6 19.5 1.7 1.4 0.0 0.0 0.0 0.9 0.0 1.9 5.7 0.9 0.9 0.0 2.8 0.3 0.7 0.0 0.0 0.0 10.4 1.1 0.3 162.7 179.8 158.2 198.3 158.1 149.3 167.9 166.0 144.5 147.4 178.7 144.5 4.6 3.2 2.0 117.2 5.1 3.2 4.7 1.3 1.2 5.7 6.2 8.0 175.1 8.6 1.9 1.8 4.2 1.2 4.9 1.3 39.2 2.0 1.0 1.2 3.7 4.4 4.2 5.7 12.7 2.6 1.9 13.4 5.1 4.1 0.0 10.1 3.9 9.1 1.9 0.0 8.3 1.6 8.2 1.9 2.3 2.3 25.1 1.6 5.4 10.3 0.0 83.7 3.1 5.0 6.3 3.3 1.6 28.2 2.3 5.7 5.4 33.5 0.8 36.5 26.3 12.7 36.7 1.8 4.9 3.5 2.8 0.8 9.3 3.2 1.6 5.6 SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" 48.2 11.3 71.0 12.0 168.3 21.4 25.1 124.3 114.2 17.7 21.5 29.5 22.1 24.7 139.8 41.5 27.5 17.8 64.7 131.8 90.0 38.7 6.5 37.4 2.8 151.9 133.8 6.1 17.5 46.5 11.3 44.8 153.1 18.3 26.9 40.0 25.2 44.0 85.0 19.0 21.9 27.8 102.8 10.2 18.2 43.5 118.0 6.4 42.7 71.8 10.3 16.9 18.0 285.6 38.8 15.3 37.5 45.8 107.0 21.2 107.3 28.2 44.9 27.2 29.0 39.8 14.0 0.3 35.2 11.9 19.9 9.4 44.7 22.3 38.9 1.1 21.2 10.7 23.5 43.1 41.8 0.2 33.5 53.2 3.6 33.3 7.3 72.6 4.2 31.7 81.3 4.0 38.7 41.1 27.9 0.8 14.1 17.5 6.3 30.7 87.9 18.9 52.0 27.8 38.3 21.8 16.6 109.3 120.6 53.1 46.1 6.7 1.1 5.8 21.7 1.0 47.6 37.0 32.2 0.3 9.8 0.3 24.3 0.0 7.1 2.5 0.0 9.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.8 0.4 10.8 1.6 0.0 2.0 71.0 168.3 124.3 114.2 131.8 90.0 151.9 133.8 153.1 102.8 118.0 285.6 10.6 38.5 47.9 54.5 1.9 1.3 4.7 6.7 1.2 14.9 27.5 14.2 98.9 27.1 20.3 75.4 35.5 30.6 3.2 70.2 5.9 23.9 65.1 33.2 5.2 15.9 16.8 4.0 87.9 23.7 30.2 9.8 16.8 34.9 7.6 10.4 7.9 22.1 30.1 13.5 56.7 27.7 6.1 38.7 9.9 79.7 8.7 34.6 21.4 78.7 37.7 21.7 0.0 48.7 447.8 25.6 23.2 49.7 1.5 7.1 64.0 13.1 29.6 50.7 32.9 25.1 53.6 46.3 21.6 9.3 1.8 36.8 2.1 1.8 28.3 10.8 SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.1" "Group enriched" "Detected in many" 8 "Adipocytes: 464.9;Endometrial ciliated cells: 377.3;Endothelial cells: 171.5;Glandular and luminal cells: 520.0" "Group enriched" "Detected in many" 4 "endometrial cancer: 122.8;ovarian cancer: 96.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "EFO-21: 108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB025594: , HPA068399: AB_2685981" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favorable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" 49.1 1.6 2.9 1.4 2.3 0.0 32.6 2.6 3.3 20.4 1.4 8.3 0.7 18.8 1.2 3.6 23.0 7.7 19.1 2.1 2.2 5.6 1.3 9.9 0.7 2.9 2.5 4.2 1.9 0.8 2.3 5.7 2.7 6.0 0.8 0.1 3.9 1.1 10.3 5.1 5.0 4.3 2.5 13.2 5.7 3.4 2.8 0.4 5.8 5.8 0.4 8.4 9.4 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 2.6 3.3 2.1 2.2 2.9 2.5 2.7 2.5 2.8 2.6 464.9 0.0 0.0 0.0 0.2 13.9 0.3 0.0 0.0 0.1 0.7 1.3 2.1 1.5 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 2.6 377.3 44.5 171.5 0.0 2.7 0.0 0.2 0.1 7.7 0.0 520.0 0.0 0.0 46.8 0.1 0.1 0.0 0.0 0.0 0.0 0.9 16.6 1.8 2.5 3.5 19.6 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 7.3 5.1 3.2 6.4 0.3 13.5 0.0 4.5 0.2 0.0 3.7 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 111.4" "Group enriched" "Detected in some" 4 "Distal tubular cells: 86.1;Proximal tubular cells: 202.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 17.5;HBEC3-KT: 8.9;hTERT-HME1: 12.4;SuSa: 14.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 17.1;hippocampal formation: 17.9;olfactory bulb: 7.5;pons: 8.0" "Secreted to blood" NA NA 2650000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.78e-2)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.81e-2)" "unprognostic (2.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (5.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.37e-3)" "unprognostic (9.78e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" 111.4 0.1 8.7 0.1 9.2 0.4 4.1 8.6 24.2 0.0 7.2 0.1 0.0 1.3 0.6 0.2 0.2 0.1 2.8 8.1 11.5 26.4 2.3 0.6 0.2 8.6 13.9 0.0 20.7 0.4 0.0 17.7 26.6 0.0 0.0 1.7 6.9 0.5 2.0 0.0 0.3 0.1 8.0 0.4 0.5 0.2 9.6 3.0 20.2 8.8 0.1 0.0 0.0 9.9 0.0 0.5 0.8 0.0 3.0 1.2 0.0 0.0 0.1 0.1 1.2 17.5 0.0 0.7 0.3 0.0 0.3 0.0 0.0 8.9 1.6 0.0 0.0 4.7 0.0 0.1 1.8 0.0 0.0 5.7 0.9 0.3 12.4 0.2 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 2.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 1.7 14.6 0.0 0.2 0.3 0.0 5.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.7 9.2 8.6 24.2 8.1 11.5 8.6 13.9 26.6 8.0 9.6 9.9 1.4 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 3.0 0.7 0.9 28.9 0.0 0.0 25.8 0.0 0.0 0.1 0.0 86.1 0.4 0.0 0.5 0.3 0.6 0.0 0.0 0.0 19.1 0.0 1.7 0.0 2.5 0.0 0.0 0.7 0.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 13.7 0.0 0.0 1.2 4.9 4.1 0.0 0.1 2.5 0.0 0.0 0.0 0.1 0.0 202.2 0.0 0.5 0.0 2.4 0.9 0.0 1.8 0.0 0.0 0.4 1.0 0.1 0.0 0.1 SSC4D "S4D-SRCRB, SRCRB-S4D, SRCRB4D" ENSG00000146700 "Scavenger receptor cysteine rich family member with 4 domains" Q8WTU2 7 76389334-76409697 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.6;parathyroid gland: 7.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.0;Distal tubular cells: 3.9;Hepatocytes: 3.7;Spermatogonia: 3.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "EFO-21: 6.7;Hep G2: 9.6;SuSa: 10.7;U-2 OS: 25.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062611 Uncertain "Secreted - unknown location" NA NA 980000 "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 7: Non-specific - Mitochondria" "HPA062611: AB_2684807" "unprognostic (3.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (2.83e-6)" "prognostic unfavorable (7.08e-4)" "unprognostic (3.52e-2)" "unprognostic (3.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.49e-2)" "unprognostic (8.49e-3)" "unprognostic (3.18e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (2.59e-1)" "unprognostic (3.90e-1)" "unprognostic (2.56e-2)" "unprognostic (1.73e-2)" 0.7 0.3 0.2 0.0 0.4 0.0 0.3 0.0 0.2 0.3 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 2.6 0.4 0.1 0.0 0.2 0.2 0.7 2.2 7.0 2.6 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.1 0.0 0.5 0.0 0.0 1.0 0.0 0.3 0.0 0.8 0.2 0.0 0.0 0.1 1.0 0.5 0.0 0.0 10.7 0.2 0.0 0.0 0.0 25.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.2 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.5 1.6 0.1 0.0 0.5 0.0 0.6 0.4 1.4 1.4 2.1 0.0 0.0 11.0 0.0 0.3 0.0 0.2 3.9 1.9 0.1 0.5 0.1 0.3 0.0 0.0 1.6 1.7 1.4 0.4 0.0 0.4 0.0 0.7 1.1 3.7 2.8 1.7 1.4 0.1 0.0 0.6 0.0 0.4 0.9 0.9 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.4 0.1 0.4 0.0 0.4 0.4 1.3 0.0 0.2 0.0 0.8 0.6 0.6 3.5 1.0 0.0 0.3 0.1 0.6 0.2 0.4 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STAT5A "MGF, STAT5" ENSG00000126561 "Signal transducer and activator of transcription 5A" P42229 17 42287547-42311943 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Lactation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 78.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 101.0;HEL: 153.5;HMC-1: 85.2;K-562: 262.4;MOLT-4: 163.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003860, HPA027873, HPA042128, HPA049883, HPA051156" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Cytosol" "CAB003860: AB_562347, HPA027873: AB_10603893, HPA042128: AB_2677864, HPA049883: AB_2680931, HPA051156: AB_2681366" "prognostic favorable (5.87e-4)" "unprognostic (3.09e-3)" "unprognostic (2.31e-2)" "unprognostic (1.76e-1)" "unprognostic (1.43e-1)" "unprognostic (3.41e-3)" "unprognostic (2.15e-1)" "unprognostic (6.22e-2)" "unprognostic (3.33e-1)" "unprognostic (6.82e-3)" "unprognostic (2.76e-1)" "unprognostic (2.11e-1)" "unprognostic (3.85e-2)" "unprognostic (5.74e-2)" "unprognostic (1.90e-2)" "unprognostic (1.98e-1)" "unprognostic (5.49e-3)" 78.9 40.6 4.3 28.9 5.7 52.1 48.8 5.3 4.8 19.1 5.4 24.0 8.6 17.8 5.7 9.9 19.0 13.9 13.9 3.6 7.5 13.9 8.1 23.3 37.5 8.0 7.6 22.5 12.2 2.4 10.5 7.3 7.4 15.4 9.1 1.2 15.7 13.7 23.8 18.4 22.4 14.3 6.7 29.8 14.0 4.9 7.7 24.4 13.3 13.8 27.1 24.1 15.4 8.6 3.9 4.9 0.5 0.0 35.7 17.5 0.4 2.1 8.6 4.0 2.3 0.0 3.7 0.3 9.0 8.5 0.2 0.3 0.8 0.3 1.1 101.0 0.0 153.5 9.3 1.3 15.5 13.5 85.2 36.8 2.1 1.7 2.0 0.0 12.3 2.0 262.4 0.1 2.3 0.1 163.5 64.7 1.4 2.5 0.0 4.5 1.1 13.8 1.1 2.6 0.3 0.0 10.0 3.9 17.8 0.9 2.5 13.9 7.2 8.0 2.6 3.9 0.1 0.2 0.1 0.0 1.0 25.4 2.5 9.8 15.1 7.9 10.3 18.6 14.4 8.2 18.3 15.2 18.7 6.6 18.0 15.0 18.3 17.4 24.9 6.6 14.5 12.9 4.3 5.7 5.3 4.8 3.6 7.5 8.0 7.6 7.4 6.7 7.7 8.6 14.0 0.0 10.6 2.6 18.7 7.4 3.8 4.5 5.7 2.9 35.8 24.5 29.6 5.7 3.4 5.5 0.0 1.2 17.7 5.5 5.9 5.0 0.4 7.2 5.2 21.2 0.0 33.2 0.2 13.6 2.9 15.3 5.1 11.9 22.8 6.8 6.1 3.3 21.4 0.0 1.3 4.2 0.0 24.5 41.3 3.5 32.6 31.8 8.8 5.6 41.0 3.9 8.2 2.5 5.0 9.6 8.1 41.0 12.5 12.2 1.8 14.4 8.4 0.7 6.6 13.7 10.2 0.0 0.9 4.4 7.7 1.4 29.2 7.7 6.5 7.0 STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 130.3;skeletal muscle: 248.5;tongue: 154.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.1;Ductal cells: 7.9;Glandular and luminal cells: 5.1;Plasma cells: 7.0;Proximal enterocytes: 19.5;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 140.7;U-266/70: 62.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" 109.7 5.3 4.3 7.3 4.0 19.9 11.8 3.5 6.3 7.0 2.9 29.0 9.6 9.3 3.2 15.1 13.7 12.8 52.7 4.0 7.0 10.0 130.3 14.1 1.3 6.7 5.4 10.0 12.0 7.9 1.7 16.8 6.2 20.7 26.4 4.0 4.7 13.9 248.5 1.5 26.1 28.0 5.6 2.2 15.5 9.7 5.6 1.3 2.6 154.7 2.1 22.1 4.5 5.6 15.9 9.9 2.0 10.0 46.3 13.9 12.7 21.9 21.6 12.0 12.6 12.6 17.9 0.0 13.1 25.8 26.2 9.2 9.6 6.1 7.4 52.4 3.6 1.7 18.2 16.5 4.8 9.5 10.5 7.1 24.0 10.2 8.2 32.4 0.9 0.0 0.6 140.7 23.7 13.0 0.6 7.4 2.5 24.1 7.2 0.0 3.8 9.9 8.0 17.2 2.6 17.7 12.9 20.2 0.3 5.0 4.9 3.7 3.9 11.6 5.9 29.4 12.5 62.8 17.1 0.0 19.6 7.5 5.4 0.1 2.6 5.7 2.0 3.1 1.1 0.1 2.4 2.4 2.5 0.0 0.5 0.9 0.3 4.4 1.2 0.3 0.8 1.3 4.3 4.0 3.5 6.3 4.0 7.0 6.7 5.4 6.2 5.6 5.6 5.6 0.0 0.0 0.5 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.2 9.1 0.0 7.9 0.0 2.8 1.5 0.1 0.0 0.4 0.0 3.9 1.4 1.0 2.6 5.1 0.0 0.3 0.0 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 3.3 2.9 0.0 7.0 0.5 19.5 0.3 6.6 0.0 0.0 1.1 3.0 0.2 0.0 1.1 0.0 0.8 0.3 0.3 1.4 0.9 STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 454.6;Erythroid cells: 535.1;Hepatocytes: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 591.3;hTCEpi: 497.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" 339.0 117.3 100.4 101.0 108.1 358.2 243.8 94.7 103.9 129.3 74.8 226.0 46.1 139.9 72.2 87.8 141.7 153.3 219.7 90.5 113.1 123.9 355.4 290.7 67.7 120.7 115.1 81.3 38.9 45.3 49.8 272.7 108.9 111.6 58.4 15.0 95.5 93.4 102.6 118.3 114.1 155.9 105.2 121.6 139.3 24.7 111.0 33.8 112.9 106.2 46.4 182.4 129.6 108.7 8.4 55.0 4.8 26.0 591.3 170.3 0.4 138.6 149.3 40.7 64.5 7.6 10.8 66.5 34.3 186.6 23.9 14.7 31.7 133.0 79.3 41.7 12.0 144.7 108.8 23.1 299.0 61.4 32.4 272.2 497.3 60.9 88.0 11.7 152.5 21.0 33.3 88.2 96.8 45.2 2.2 47.0 64.4 3.5 16.6 8.7 0.2 147.7 34.7 1.7 5.9 0.5 114.5 107.8 62.1 44.9 36.6 47.4 172.8 92.0 28.1 91.3 13.6 36.5 44.9 4.4 35.1 58.1 51.0 21.4 35.5 4.1 168.9 55.8 165.7 5.9 84.2 153.3 35.8 4.2 15.0 81.1 20.8 147.1 41.0 6.1 8.7 128.8 100.4 108.1 94.7 103.9 90.5 113.1 120.7 115.1 108.9 105.2 111.0 108.7 454.6 160.3 96.6 30.0 13.2 105.5 251.8 107.0 62.0 5.0 135.8 72.3 36.7 121.5 159.0 35.0 6.2 121.9 72.1 26.3 3.9 56.6 3.6 97.0 75.4 313.6 0.0 535.1 3.2 22.0 54.7 140.3 17.9 11.7 36.1 76.0 282.7 371.2 92.1 3.3 4.8 1.1 54.9 226.3 92.3 9.0 66.5 105.9 88.9 70.3 37.9 8.6 127.7 6.6 4.5 39.1 18.3 103.0 16.9 90.2 33.8 92.8 216.0 5.0 138.1 73.2 188.1 40.8 13.7 48.4 119.1 172.8 98.8 81.8 2.2 200.0 STOX1 "C10orf24, FLJ25162" ENSG00000165730 "Storkhead box 1" Q6ZVD7 10 68827531-68895432 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.2;choroid plexus: 30.8" "Group enriched" "Detected in many" 5 "Astrocytes: 85.2;Endometrial ciliated cells: 67.4;Respiratory ciliated cells: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 8.6;HAP1: 8.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037844, HPA037845" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Intracellular and membrane" No NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA037844: AB_2675700, HPA037845: AB_10671369" "prognostic favorable (3.37e-5)" "unprognostic (5.53e-3)" "unprognostic (6.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.63e-3)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "prognostic favorable (2.08e-4)" "unprognostic (1.52e-1)" "unprognostic (2.45e-3)" "unprognostic (5.33e-3)" "unprognostic (5.29e-2)" "unprognostic (3.87e-2)" "unprognostic (8.77e-2)" "unprognostic (3.06e-2)" "unprognostic (2.33e-1)" "unprognostic (3.46e-2)" 6.3 5.1 26.4 0.5 23.6 0.2 4.2 14.9 33.2 1.9 30.8 1.6 1.1 1.6 7.4 1.4 12.5 0.9 0.4 23.9 22.4 2.8 0.3 1.3 1.2 16.5 24.9 1.1 1.4 6.5 7.2 0.8 17.4 1.2 1.6 0.7 1.6 1.1 1.3 0.9 2.1 0.8 16.3 0.4 3.4 2.5 26.2 6.7 3.1 0.8 1.0 2.5 0.7 20.5 1.8 2.0 4.2 8.6 1.8 0.0 2.5 0.2 0.1 1.2 1.3 1.8 2.6 1.7 2.4 0.0 3.3 0.5 8.1 0.0 0.6 2.0 3.4 0.1 0.4 2.6 0.2 2.3 3.1 0.2 0.1 0.2 0.0 0.2 0.1 4.5 0.4 0.2 0.1 1.8 3.9 2.8 1.4 0.4 1.2 2.8 0.1 0.0 2.6 4.6 1.3 3.9 3.1 0.8 0.6 2.7 1.9 1.8 0.0 0.0 0.2 0.0 1.3 0.7 1.6 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.0 1.0 0.0 0.0 26.4 23.6 14.9 33.2 23.9 22.4 16.5 24.9 17.4 16.3 26.2 20.5 0.3 0.0 0.5 85.2 0.3 1.5 4.5 0.9 1.2 0.7 5.1 4.1 0.5 0.0 5.6 1.8 0.0 1.6 3.1 0.4 3.9 0.1 0.3 67.4 1.7 0.4 0.0 1.7 11.4 0.4 0.5 0.6 0.5 4.2 2.5 0.8 0.0 0.2 0.1 0.0 9.9 2.5 2.0 0.3 0.7 0.7 1.2 0.2 0.0 1.9 0.1 1.9 2.1 6.0 2.1 0.1 0.3 0.0 0.6 1.7 0.8 1.8 42.8 0.4 6.6 1.5 5.0 1.4 8.8 0.4 0.4 1.2 0.7 6.9 5.3 1.8 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SV2B "HsT19680, KIAA0735" ENSG00000185518 "Synaptic vesicle glycoprotein 2B" Q7L1I2 15 91099950-91302565 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 34.5;retina: 56.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 137.1;Cone photoreceptor cells: 150.1;Excitatory neurons: 455.0;Rod photoreceptor cells: 139.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 2.1;SCLC-21H: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046247 Approved NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046247: AB_10963538" "unprognostic (2.92e-1)" "unprognostic (7.92e-2)" "unprognostic (1.32e-3)" "unprognostic (4.01e-5)" "unprognostic (2.66e-3)" "unprognostic (7.77e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (9.89e-2)" "unprognostic (1.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.39e-1)" "unprognostic (3.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-2)" "unprognostic (3.10e-4)" 1.8 1.1 17.2 0.2 17.5 0.1 0.8 7.3 34.5 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.2 0.8 22.4 0.0 0.3 0.1 0.2 0.4 8.5 0.0 0.0 1.4 0.1 1.0 0.2 10.7 0.8 0.3 56.3 1.0 0.1 0.6 0.2 0.4 0.2 0.0 0.2 0.3 0.8 1.4 0.6 0.2 1.0 1.2 0.1 0.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.2 17.5 7.3 34.5 22.4 0.0 8.5 0.0 10.7 0.0 1.4 14.8 10.9 0.0 0.0 7.2 0.1 0.4 0.1 0.1 0.0 137.1 0.2 0.5 3.0 1.5 0.0 0.0 150.1 0.0 0.0 0.0 0.0 4.2 6.4 0.0 0.0 3.3 0.0 0.0 455.0 5.0 0.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.1 3.3 11.4 0.0 0.0 0.0 0.4 2.0 0.0 0.2 0.0 27.2 0.0 43.4 0.0 5.5 39.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 139.0 0.0 0.5 0.2 8.0 0.4 0.1 0.1 0.0 0.1 0.1 0.0 0.2 SYNE3 "C14orf139, C14orf49, FLJ25605, LINC00341, NCRNA00341, Nesp3, Nesprin-3, NET53" ENSG00000176438 "Spectrin repeat containing nuclear envelope family member 3" Q6ZMZ3 14 95407266-95475836 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 70.2;Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 103.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 46.5;ASC TERT1: 36.2;Karpas-707: 42.3;REH: 34.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055227, HPA077140" Approved Supported "Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear membrane" "HPA055227: AB_2682747, HPA077140: AB_2686826" "unprognostic (4.63e-2)" "unprognostic (6.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.48e-3)" "unprognostic (7.15e-2)" "unprognostic (2.12e-3)" "unprognostic (2.45e-1)" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.87e-1)" "unprognostic (8.50e-2)" "unprognostic (3.32e-1)" "unprognostic (7.41e-6)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.19e-2)" 19.1 3.4 5.1 4.3 9.5 13.7 12.6 5.8 6.7 4.0 8.7 2.8 1.5 2.3 1.4 2.0 4.5 2.1 4.3 4.5 5.5 1.1 3.0 4.4 6.0 10.0 8.0 4.0 0.9 0.4 1.7 3.4 7.4 1.6 2.6 11.9 3.2 1.1 2.2 4.3 3.8 2.2 5.6 5.0 2.1 2.7 8.3 2.4 2.9 3.3 6.0 3.2 4.1 12.3 1.2 0.1 0.7 1.1 46.5 36.2 14.3 5.4 9.4 5.1 4.0 7.8 1.3 6.3 0.9 2.6 1.6 0.3 1.1 4.0 2.3 20.9 0.9 4.3 0.9 2.1 6.0 6.6 10.4 10.2 1.4 6.4 3.7 0.4 9.0 1.9 0.3 42.3 3.9 1.5 3.9 7.3 0.1 0.2 2.6 34.8 23.2 13.5 0.6 0.7 1.0 5.1 0.2 0.1 2.5 0.6 2.0 9.6 8.2 3.7 2.2 5.0 0.7 5.0 11.1 5.9 7.4 14.6 28.2 2.2 1.9 0.1 0.7 1.5 0.9 1.2 1.0 0.8 0.8 1.0 1.2 1.0 0.9 0.3 1.6 1.0 0.9 1.0 5.1 9.5 5.8 6.7 4.5 5.5 10.0 8.0 7.4 5.6 8.3 12.3 12.4 9.6 18.3 3.3 19.7 2.3 0.4 0.1 0.6 5.1 1.0 1.3 70.2 0.0 0.7 0.0 62.6 2.2 16.1 4.9 0.0 0.0 3.9 6.5 5.1 14.7 1.2 4.0 2.5 0.4 15.0 22.3 1.1 1.4 12.0 0.2 5.0 6.8 4.3 6.7 3.3 5.0 0.0 17.6 14.8 2.4 13.1 20.3 5.4 3.7 27.8 5.3 9.2 14.1 20.8 0.5 6.2 0.4 20.6 1.9 2.9 0.4 6.6 103.7 6.6 19.1 12.1 0.6 1.1 0.3 1.0 1.9 14.0 0.0 1.9 0.5 TAMALIN GRASP ENSG00000161835 "Trafficking regulator and scaffold protein tamalin" Q7Z6J2 12 52006946-52015889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 243.8;B-cells: 60.6;dendritic cells: 114.1;Macrophages: 60.6;Plasma cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 37.4;TIME: 27.4;WM-115: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040664, HPA062028" Approved Approved "Nuclear bodies,Vesicles" No NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "Nuclear bodies" "HPA040664: AB_10794066, HPA062028: AB_2684664" "unprognostic (1.90e-1)" "unprognostic (1.29e-2)" "unprognostic (2.48e-2)" "unprognostic (2.39e-2)" "unprognostic (2.00e-2)" "unprognostic (2.38e-2)" "unprognostic (2.23e-2)" "unprognostic (1.93e-1)" "unprognostic (2.86e-1)" "unprognostic (8.71e-2)" "unprognostic (3.16e-3)" "unprognostic (7.20e-2)" "unprognostic (3.90e-3)" "unprognostic (1.99e-3)" "unprognostic (1.44e-1)" "unprognostic (3.53e-2)" "unprognostic (2.77e-2)" 31.9 6.3 9.8 4.1 14.9 23.8 26.9 3.2 21.5 17.6 0.4 9.4 2.2 22.0 1.6 7.1 22.2 9.6 24.2 10.5 3.7 12.2 4.2 46.8 3.8 5.0 4.9 14.9 5.7 2.8 6.2 8.9 4.8 13.0 1.9 0.1 6.5 3.1 10.6 10.7 9.8 6.0 4.1 18.2 8.6 2.6 7.6 3.7 16.3 8.4 2.3 12.5 17.1 7.1 0.0 0.0 4.4 0.2 1.9 3.6 1.0 0.2 1.1 0.0 1.1 0.0 0.0 0.0 10.0 0.0 0.4 0.1 1.3 0.0 0.4 0.2 1.3 0.3 0.0 6.2 7.4 0.3 3.3 7.2 0.0 0.3 0.0 0.0 37.4 1.0 1.6 0.0 0.9 0.2 3.1 10.5 4.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 1.1 1.6 0.0 0.2 7.5 2.7 0.0 0.3 27.4 0.0 2.5 0.2 0.0 0.2 0.0 0.1 0.6 0.0 50.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 9.8 14.9 3.2 21.5 10.5 3.7 5.0 4.9 4.8 4.1 7.6 7.1 243.8 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.2 114.1 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 TBC1D16 "FLJ20748, MGC25062" ENSG00000167291 "TBC1 domain family member 16" Q8TBP0 17 79932343-80035872 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 307.9" "Cancer enhanced" "Detected in all" "melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.3" "Lineage enhanced" "Detected in single" "monocytes: 2.3" "Cell line enhanced" "Detected in many" "ASC diff: 179.1;SK-MEL-30: 192.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024482, HPA065839" Approved Approved "Intermediate filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Intermediate filaments" "HPA024482: AB_1857790, HPA065839: AB_2685566" "unprognostic (4.53e-3)" "unprognostic (1.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.06e-2)" "unprognostic (4.92e-2)" "unprognostic (7.21e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (5.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-3)" "unprognostic (3.99e-3)" 37.3 8.1 17.6 8.7 24.8 0.9 18.4 24.4 14.6 10.4 5.3 8.0 7.9 12.4 11.5 10.1 12.9 9.5 10.7 10.6 15.2 27.7 7.4 9.0 7.8 18.0 22.7 11.7 15.7 12.9 7.0 7.5 16.0 17.7 5.9 7.6 29.4 10.8 5.1 17.3 9.0 10.5 13.0 7.3 8.4 4.1 38.9 4.0 10.1 6.7 3.5 8.6 6.2 17.4 30.3 28.2 43.1 50.8 179.1 93.7 8.2 17.3 17.1 10.7 12.0 53.6 10.3 0.1 11.9 29.2 20.3 9.4 45.8 16.2 8.2 1.5 21.5 0.0 13.3 25.1 30.5 0.6 4.1 106.1 28.1 23.2 16.7 17.1 45.9 19.8 7.2 19.6 20.2 18.4 8.1 2.7 51.8 39.3 15.4 25.4 27.2 17.5 12.6 36.5 43.8 56.8 15.4 42.5 192.4 26.7 27.9 13.6 31.3 37.1 26.1 29.5 15.3 59.9 11.4 3.3 15.9 11.2 47.8 0.0 0.1 0.0 0.0 1.9 0.2 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.0 2.3 0.0 0.0 0.2 17.6 24.8 24.4 14.6 10.6 15.2 18.0 22.7 16.0 13.0 38.9 17.4 5.7 0.0 7.9 15.7 1.7 5.5 5.2 4.3 2.8 8.5 12.3 7.5 8.1 17.2 5.5 7.3 10.4 6.1 0.3 3.1 9.8 15.1 0.9 15.3 22.7 10.4 31.8 3.6 7.3 22.1 1.5 17.5 9.7 26.0 7.6 23.8 14.6 17.9 3.2 307.9 8.9 6.3 14.2 58.4 3.1 2.2 5.9 6.4 76.5 37.5 0.9 23.1 2.1 14.6 4.9 17.4 4.8 7.9 0.4 12.5 3.5 13.5 8.2 7.0 6.6 19.3 10.3 0.3 4.3 5.8 4.5 1.9 2.7 7.6 7.0 5.9 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8;placenta: 13.1" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 635.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;BEWO: 63.3;HDLM-2: 90.0;T-47d: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047043 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA047043: AB_2679914" "unprognostic (5.79e-2)" "unprognostic (3.01e-2)" "unprognostic (6.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (8.28e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (4.85e-2)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (5.25e-4)" 5.0 5.1 12.0 1.6 18.4 0.0 2.0 0.0 12.3 1.5 0.0 4.3 0.8 2.9 0.6 0.8 1.0 2.4 1.4 21.8 8.1 0.9 0.3 0.8 0.8 2.8 7.3 3.8 1.2 5.1 4.5 13.1 0.0 3.7 0.8 3.9 0.6 3.6 2.1 0.4 0.9 2.3 0.8 2.2 0.7 2.1 7.4 2.8 6.1 4.3 1.2 1.6 1.4 2.0 0.3 2.6 66.3 0.4 13.2 23.5 63.3 7.8 2.7 6.9 6.1 33.9 17.6 0.0 0.9 52.6 28.6 3.3 16.0 3.4 6.8 90.0 26.7 0.0 0.0 0.0 1.3 0.0 0.0 31.2 1.2 21.5 15.0 15.4 9.6 0.0 0.0 0.4 10.6 2.3 0.1 0.1 21.4 0.0 2.8 0.0 17.1 0.2 0.1 0.1 27.2 25.2 4.0 0.5 0.1 35.8 86.0 3.4 21.2 53.7 38.2 0.2 39.6 0.0 0.0 0.0 28.2 0.0 40.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 18.4 0.0 12.3 21.8 8.1 2.8 7.3 0.0 0.8 7.4 2.0 0.1 0.0 0.0 23.8 0.0 0.4 0.2 0.7 1.8 50.8 1.6 2.2 3.9 0.0 0.1 3.7 4.2 112.7 0.0 0.0 1.9 0.1 12.4 0.1 4.5 0.7 5.3 0.0 115.6 1.8 54.6 4.1 0.0 0.6 0.0 7.7 1.1 0.7 10.4 5.0 635.6 0.0 0.0 0.0 0.7 3.2 8.4 0.0 1.8 8.4 0.0 10.6 0.0 12.1 24.4 0.4 0.0 2.6 0.0 0.4 0.0 0.3 0.0 3.1 0.0 4.8 3.2 3.8 7.2 1.8 0.0 133.4 0.1 4.1 0.1 0.1 TENT5A "C6orf37, FAM46A, FLJ20037" ENSG00000112773 "Terminal nucleotidyltransferase 5A" Q96IP4 6 81491439-81752774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 225.9;salivary gland: 104.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 73.1;Endometrial stromal cells: 70.6;Extravillous trophoblasts: 115.4;Glandular and luminal cells: 176.7;Syncytiotrophoblasts: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 81.9;HeLa: 86.1;HL-60: 95.6;THP-1: 162.0;U-937: 72.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051067, HPA067140" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA051067: , HPA067140: AB_2685788" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (5.39e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (2.62e-3)" "unprognostic (5.93e-2)" "unprognostic (2.48e-2)" "unprognostic (2.53e-1)" "unprognostic (1.03e-1)" "unprognostic (1.40e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (7.18e-2)" "unprognostic (6.38e-2)" "unprognostic (9.25e-2)" "unprognostic (9.66e-2)" 13.5 21.3 4.3 7.9 4.6 225.9 12.2 9.0 5.8 21.3 9.9 17.2 16.4 10.2 19.7 4.4 12.0 32.3 21.7 4.0 14.0 6.4 35.9 9.1 5.2 7.8 7.1 23.6 8.3 9.4 17.4 18.7 6.1 9.9 16.9 8.7 104.4 24.8 2.1 18.7 22.2 11.1 5.0 9.9 37.8 3.7 6.7 2.9 8.8 5.1 4.3 16.6 8.8 5.3 3.5 5.0 3.3 0.2 67.9 29.8 6.2 27.0 19.2 15.7 23.5 51.0 2.6 0.3 1.0 81.9 10.0 2.9 2.4 4.2 11.5 0.0 6.2 0.1 86.1 8.0 21.2 95.6 7.1 13.2 2.4 12.3 2.1 51.2 2.0 0.8 1.4 0.0 10.6 14.7 0.0 67.2 0.9 29.2 3.8 0.0 28.8 0.1 2.1 6.2 3.3 4.4 12.1 5.2 8.3 9.9 1.2 162.0 4.5 17.9 3.8 7.6 7.6 0.4 0.3 0.3 25.3 72.7 7.8 37.3 29.9 46.3 11.5 29.6 6.8 18.2 4.3 5.7 24.2 21.0 8.1 8.0 13.8 16.9 47.3 8.5 5.6 14.0 4.3 4.6 9.0 5.8 4.0 14.0 7.8 7.1 6.1 5.0 6.7 5.3 22.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 40.8 44.2 0.0 0.0 0.0 5.5 0.0 39.9 43.1 0.0 3.9 30.5 0.0 73.1 70.6 2.9 0.0 0.0 0.0 23.4 115.4 32.7 0.0 176.7 0.0 40.9 0.0 0.0 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 26.7 0.0 0.0 5.9 0.0 0.0 3.6 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 162.0 9.4 12.6 0.0 0.0 TESK1 ENSG00000107140 "Testis associated actin remodelling kinase 1" Q15569 9 35605262-35610041 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "unprognostic (5.17e-2)" "unprognostic (2.82e-1)" "unprognostic (4.96e-3)" "unprognostic (5.18e-2)" "unprognostic (2.04e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (1.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.66e-3)" "unprognostic (1.22e-2)" "unprognostic (2.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-3)" 40.2 44.7 24.4 11.2 22.0 6.1 33.5 17.9 25.9 22.6 14.8 29.9 13.3 25.7 11.1 12.8 18.7 13.0 19.2 22.0 21.3 18.0 13.8 19.9 11.9 20.6 24.2 15.9 16.0 16.8 26.6 9.1 21.8 22.4 8.5 6.7 17.4 19.8 69.2 19.1 18.9 17.1 18.2 16.2 22.2 57.0 28.1 10.4 19.0 27.6 8.5 27.9 16.0 20.4 17.0 16.0 10.7 16.9 42.5 17.5 12.1 19.7 17.3 17.8 11.3 9.3 4.8 30.9 10.3 19.7 47.1 5.8 6.8 14.1 3.4 20.0 9.2 4.6 14.1 8.4 24.4 4.0 14.6 17.2 21.8 13.9 19.0 18.9 12.6 15.3 5.3 11.3 18.0 19.1 7.9 18.4 6.2 16.1 18.6 12.9 6.6 7.3 13.1 8.0 8.8 10.3 11.2 13.0 8.1 7.3 15.9 5.7 11.1 39.2 16.2 27.9 12.0 6.0 10.2 11.2 28.2 4.6 9.1 0.0 0.6 0.1 1.1 0.1 1.0 0.3 0.4 1.8 0.8 0.2 0.5 0.5 0.0 0.9 0.3 0.8 0.1 0.7 24.4 22.0 17.9 25.9 22.0 21.3 20.6 24.2 21.8 18.2 28.1 20.4 13.4 6.4 7.7 9.1 8.9 14.4 6.3 5.9 4.6 10.9 13.9 11.0 1.9 7.2 4.2 7.3 8.4 3.8 20.0 19.9 1.9 6.6 35.1 5.6 9.2 9.7 9.5 1.7 6.5 10.4 8.6 9.0 18.8 11.2 1.3 10.1 10.8 8.4 13.9 13.5 8.5 14.8 0.0 7.8 22.4 34.9 12.2 19.3 14.2 2.8 6.3 12.6 20.6 4.5 6.8 10.2 11.0 14.3 10.7 19.2 13.4 7.8 4.2 15.3 6.6 10.1 10.9 14.8 10.0 4.7 13.9 3.3 11.8 5.4 7.3 9.7 THRSP "Lpgp, LPGP1, S14, SPOT14, THRP" ENSG00000151365 "Thyroid hormone responsive" Q92748 11 78063861-78068351 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 210.0;liver: 408.9" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 128.4" "Cancer enhanced" "Detected in many" "liver cancer: 44.1" "Region enriched" "Detected in single" 6 "cerebellum: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "ASC diff: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040642 Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA040642: AB_10794878" "unprognostic (1.19e-1)" "unprognostic (2.88e-1)" "unprognostic (2.84e-1)" "unprognostic (2.73e-2)" "unprognostic (3.07e-1)" "unprognostic (9.91e-3)" "unprognostic (1.59e-2)" "unprognostic (9.60e-2)" "unprognostic (1.07e-2)" "unprognostic (8.23e-2)" "unprognostic (1.68e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (9.64e-2)" "unprognostic (1.57e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.69e-3)" 210.0 5.9 0.1 0.4 0.1 0.0 95.3 2.7 0.3 0.1 0.0 2.6 0.0 0.1 0.4 0.3 1.0 3.4 18.6 0.2 0.0 4.6 408.9 0.1 0.7 0.0 0.2 0.1 3.6 15.5 0.1 0.0 0.4 0.1 0.2 1.5 48.9 2.3 8.2 33.7 4.6 0.5 0.0 0.1 0.7 0.1 0.0 0.2 5.7 3.3 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.3 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 2.3 21.1 11.2 0.1 4.3 0.0 0.0 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.6 0.1 0.4 0.0 2.7 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.1 2.9 128.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.1 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 38.7" "Group enriched" "Detected in some" 10 "dendritic cells: 64.2;NK-cells: 69.0;T-cells: 78.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 195.5" "Lineage enriched" "Detected in many" 11 "T-cells: 195.5" "Cell line enhanced" "Detected in single" "HDLM-2: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.24e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.22e-3)" "unprognostic (2.22e-6)" "unprognostic (9.84e-2)" "prognostic favorable (3.96e-4)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.50e-4)" "unprognostic (3.51e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.30e-8)" "unprognostic (3.54e-2)" "unprognostic (1.33e-1)" "unprognostic (7.62e-2)" "unprognostic (6.18e-3)" 0.7 0.3 0.3 12.1 0.5 2.1 0.7 0.6 0.5 0.8 0.2 2.1 1.7 0.9 0.7 2.1 0.5 3.6 0.7 0.4 0.4 0.4 2.9 2.9 38.7 0.8 0.5 0.5 0.2 0.1 0.2 0.3 0.7 1.4 2.4 0.3 1.8 0.2 0.1 1.0 5.2 0.9 0.4 15.0 3.7 0.8 0.7 9.0 0.9 0.0 20.4 5.1 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.5 0.0 0.2 0.1 0.0 0.4 0.2 0.1 29.8 0.2 3.5 1.4 48.5 90.3 0.2 0.9 5.2 39.8 0.7 17.3 0.2 1.0 195.5 22.0 0.3 0.5 0.6 0.5 0.4 0.4 0.8 0.5 0.7 0.4 0.7 0.9 0.9 0.0 3.3 0.0 3.7 3.1 0.1 0.0 0.6 0.4 0.4 0.6 0.6 0.0 1.3 0.0 2.1 0.1 64.2 0.0 0.0 0.0 0.0 0.2 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.9 2.6 0.4 1.3 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 1.8 4.2 0.3 0.0 2.3 3.6 0.0 0.9 0.1 69.0 0.0 0.1 0.0 0.0 0.0 6.9 0.2 0.0 0.1 0.0 0.6 0.0 1.0 0.5 0.7 3.0 0.2 3.3 0.0 78.4 0.0 0.2 0.0 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TIMP4 ENSG00000157150 "TIMP metallopeptidase inhibitor 4" Q99727 3 12153068-12158912 "Plasma proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 177.7;breast: 119.6" "Cell type enriched" "Detected in many" 10 "Adipocytes: 363.9" "Cancer enriched" "Detected in many" 13 "glioma: 66.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 212.9;ASC TERT1: 53.0;HSkMC: 91.9;NTERA-2: 50.7;U-87 MG: 53.6" "Region enhanced" "Detected in all" "cerebellum: 106.1" "Region enriched" "Detected in all" 9 "cerebellum: 47.7" "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.99e-2)" "unprognostic (5.14e-3)" "unprognostic (1.02e-2)" "unprognostic (2.10e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-4)" "unprognostic (9.33e-3)" "unprognostic (4.26e-3)" "unprognostic (1.36e-1)" "unprognostic (1.74e-2)" "unprognostic (3.78e-1)" "unprognostic (6.81e-2)" "unprognostic (4.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (6.66e-5)" "unprognostic (2.86e-1)" 177.7 8.3 7.7 3.9 8.4 0.6 119.6 49.6 7.2 9.3 3.9 12.1 1.4 8.1 1.0 2.9 6.8 4.4 31.0 6.8 8.8 2.8 1.1 6.6 0.6 13.7 8.6 3.8 4.0 1.4 12.3 9.9 11.7 5.5 4.3 1.0 8.9 2.3 16.7 7.7 11.0 4.4 11.3 3.4 9.2 0.7 7.1 2.0 23.1 30.1 0.1 9.8 8.7 11.6 0.7 24.2 0.7 0.0 212.9 53.0 26.4 0.8 8.9 1.0 1.3 0.5 0.1 0.0 2.2 0.9 0.8 0.9 0.0 0.8 0.4 1.0 0.0 0.0 12.7 0.9 33.2 0.0 0.1 91.9 2.2 5.8 0.2 1.6 0.0 0.0 0.5 17.3 0.2 0.6 0.0 0.0 50.7 0.0 6.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 5.0 0.0 0.0 6.1 0.0 0.0 1.0 0.1 0.0 0.6 0.9 0.0 0.1 0.0 53.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 8.4 49.6 7.2 6.8 8.8 13.7 8.6 11.7 11.3 7.1 11.6 363.9 0.0 0.0 0.0 0.4 0.1 1.3 0.3 0.6 0.4 12.4 2.8 7.0 0.0 0.2 0.0 0.0 0.4 1.4 1.3 0.0 0.6 1.6 0.2 2.1 33.6 6.6 5.3 0.1 2.6 2.7 15.7 0.0 0.0 0.0 0.2 22.5 0.0 3.4 0.0 0.2 2.8 0.0 1.2 0.3 7.5 12.2 0.8 3.6 0.0 0.0 0.7 0.0 9.0 0.1 4.6 4.8 2.6 0.0 4.2 2.7 0.5 5.5 0.0 32.9 3.1 29.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 2.0 2.2 TKT ENSG00000163931 Transketolase P29401 3 53224712-53256052 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 667.0" "Cell type enhanced" "Detected in all" "Kupffer cells: 696.7;monocytes: 624.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 447.9;eosinophil: 274.4;intermediate monocyte: 199.0;myeloid DC: 203.8;neutrophil: 375.3;non-classical monocyte: 242.6" "Group enriched" "Detected in all" 9 "dendritic cells: 203.8;granulocytes: 375.3;monocytes: 447.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced Nucleoplasm NA NA 150000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA029480: AB_10599307, HPA029481: AB_10601895" "unprognostic (5.05e-2)" "unprognostic (3.34e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (7.21e-6)" "unprognostic (6.78e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-2)" "unprognostic (3.06e-3)" "unprognostic (1.36e-2)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.07e-1)" "unprognostic (3.29e-1)" "unprognostic (9.90e-3)" 152.2 93.2 78.0 66.2 80.0 667.0 71.9 93.2 82.3 59.7 60.5 73.2 84.2 44.7 19.2 168.5 53.7 97.2 27.4 72.3 96.9 68.2 58.1 93.4 69.2 89.2 89.9 87.7 154.0 41.4 45.6 61.2 93.8 48.8 48.8 21.7 54.9 50.9 12.8 47.0 58.1 51.6 77.4 99.8 66.1 20.2 87.9 82.9 116.1 15.2 67.4 130.9 85.5 97.2 313.0 1542.9 216.0 241.5 470.8 570.8 439.5 206.2 353.8 348.8 330.8 430.1 779.3 388.5 96.8 302.9 673.3 438.3 377.9 775.8 102.4 131.0 210.3 259.6 1022.2 655.2 573.9 321.4 168.1 416.0 437.5 418.5 213.7 949.2 444.9 323.8 188.3 164.7 144.5 381.6 338.6 358.1 737.1 603.0 367.9 201.1 98.5 726.2 550.3 520.2 139.6 103.7 383.4 605.3 365.1 656.7 188.8 437.4 335.9 107.2 164.2 320.0 401.9 94.5 190.3 235.7 234.4 321.0 203.8 51.5 447.9 274.4 17.8 199.0 22.8 39.7 25.8 20.6 203.8 21.1 26.6 20.7 375.3 30.8 242.6 34.4 36.7 312.4 78.0 80.0 93.2 82.3 72.3 96.9 89.2 89.9 93.8 77.4 87.9 97.2 79.5 134.6 125.6 46.7 92.1 79.4 384.6 325.3 287.4 41.0 99.3 80.5 14.9 75.8 149.5 62.5 29.2 349.0 69.7 139.1 80.3 197.7 6.5 87.4 79.6 81.8 52.6 150.3 16.9 269.8 249.8 80.2 168.7 95.5 62.7 123.6 75.0 83.4 256.0 37.0 23.9 149.6 142.4 696.7 110.5 8.9 157.2 333.3 76.5 17.8 624.4 88.8 46.4 17.1 39.3 193.6 81.4 106.8 109.4 337.7 141.5 219.1 99.2 46.3 52.6 35.9 102.1 16.8 30.6 409.3 67.1 413.6 78.8 427.2 276.7 413.6 TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 112.4;Proximal enterocytes: 68.9;Skeletal myocytes: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 3.4;neutrophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.0;HaCaT: 8.4;SiHa: 11.2;T-47d: 9.4" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 14.2" HPA046063 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" 10.3 9.4 0.6 1.8 0.7 2.1 4.7 1.6 0.9 3.0 2.3 7.3 6.0 1.8 1.2 4.7 2.7 1.8 2.1 0.6 0.5 1.8 7.0 3.9 0.7 1.0 0.7 2.5 1.2 1.0 1.1 1.5 1.0 1.9 5.3 10.5 2.9 0.9 1.7 2.4 6.9 1.2 0.7 1.3 4.7 0.6 1.0 0.1 1.6 0.8 0.8 3.1 3.5 1.6 1.0 1.1 1.1 3.5 8.1 9.0 0.3 1.9 1.8 1.0 0.7 6.9 3.1 0.1 1.9 3.1 1.0 8.4 1.5 0.9 0.7 0.2 0.7 0.9 2.4 0.3 2.3 0.1 2.4 7.6 3.2 1.2 2.2 2.9 0.7 0.1 0.8 0.4 0.9 1.9 0.1 0.4 0.1 3.4 0.6 0.1 5.3 0.2 0.7 2.7 0.2 0.4 11.2 1.0 1.6 1.5 9.4 0.8 2.6 0.5 2.3 2.1 0.5 0.1 0.1 0.1 0.6 0.3 1.0 3.4 0.2 0.4 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.4 0.2 0.2 1.6 0.3 0.1 0.2 0.1 0.1 0.6 0.7 1.6 0.9 0.6 0.5 1.0 0.7 1.0 0.7 1.0 1.6 19.0 51.3 55.5 0.3 1.6 0.0 8.2 0.0 4.0 7.9 5.8 9.5 2.7 17.2 18.0 11.0 129.3 4.9 2.0 112.4 0.0 7.3 1.1 12.9 10.4 14.1 9.0 11.2 0.5 9.6 2.6 14.9 20.9 13.3 15.8 3.9 18.9 24.2 5.5 0.0 0.4 24.6 0.0 6.5 0.0 1.8 13.4 10.7 0.0 3.7 1.4 11.7 0.0 0.0 0.1 13.5 40.1 5.7 3.3 6.3 68.9 1.1 19.9 57.8 6.6 124.2 17.8 0.6 0.8 9.1 0.3 4.0 5.1 5.4 35.7 13.0 TLN2 "ILWEQ, KIAA0320" ENSG00000171914 "Talin 2" Q9Y4G6 15 62390526-62844631 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 38.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.7;Inhibitory neurons: 127.2;Microglial cells: 139.6;Oligodendrocyte precursor cells: 108.6;Oligodendrocytes: 93.6;Skeletal myocytes: 135.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 59.3;hTERT-HME1: 48.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017194, HPA051828, HPA054787" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 46000000 "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites, Cytosol" "CAB017194: , HPA051828: AB_2732570, HPA054787: AB_2732587" "prognostic favorable (6.53e-4)" "unprognostic (2.61e-1)" "unprognostic (9.47e-2)" "unprognostic (8.95e-2)" "unprognostic (3.74e-1)" "unprognostic (1.43e-1)" "unprognostic (8.24e-2)" "unprognostic (9.94e-2)" "unprognostic (1.68e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (1.91e-1)" "prognostic favorable (1.81e-6)" "prognostic favorable (7.74e-4)" "unprognostic (1.34e-1)" "unprognostic (5.79e-2)" "unprognostic (2.30e-1)" 19.0 4.1 14.2 2.2 15.6 3.8 10.4 3.2 16.9 8.0 20.2 9.3 4.7 3.7 2.1 2.1 4.3 1.9 12.1 18.3 8.2 38.4 4.8 2.4 0.5 7.6 8.2 4.6 4.7 2.4 5.5 1.2 6.2 2.3 7.3 7.7 7.8 2.1 26.1 3.6 5.1 2.9 11.2 1.3 5.5 5.4 7.0 3.1 13.0 12.2 0.5 4.1 4.2 13.8 1.8 5.6 8.0 9.4 59.3 5.6 9.0 13.7 10.8 12.4 12.2 15.1 1.9 4.8 6.2 24.0 20.5 2.4 10.3 2.2 10.8 15.2 1.0 0.6 22.8 10.1 2.0 1.6 0.4 10.3 5.6 16.6 48.9 7.1 0.5 5.7 0.6 0.2 21.0 7.5 0.7 0.6 14.2 26.3 4.1 5.8 20.3 5.8 6.5 11.6 1.9 9.3 10.6 1.1 3.5 17.1 2.9 3.6 3.9 22.2 30.0 36.3 35.6 0.3 0.9 3.1 10.1 3.4 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 15.6 3.2 16.9 18.3 8.2 7.6 8.2 6.2 11.2 7.0 13.8 11.5 0.0 3.2 50.6 1.1 2.4 1.8 0.7 1.2 18.6 16.5 10.2 41.1 5.7 0.9 27.6 37.5 1.2 0.7 39.0 11.7 3.5 4.3 10.9 14.3 9.0 2.4 37.7 153.7 3.9 29.7 21.5 40.8 17.4 0.0 9.3 3.3 12.6 4.9 48.8 127.2 20.0 6.1 6.2 3.1 5.2 11.8 5.5 0.0 139.6 0.8 11.1 1.0 108.6 93.6 3.7 21.0 15.8 0.7 1.5 14.6 35.1 0.1 48.3 0.0 135.6 12.3 6.7 24.5 3.1 1.6 1.4 1.3 25.8 37.7 1.7 TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 246.0" "Cell type enhanced" "Detected in all" "Granulosa cells: 482.7;Hepatocytes: 220.6;Muller glia cells: 204.7;Theca cells: 204.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 69.2;RPTEC TERT1: 86.2;T-47d: 143.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" 63.4 246.0 27.8 2.6 28.5 4.1 29.1 32.8 33.9 17.4 64.1 7.8 9.4 3.4 17.0 39.6 12.8 7.0 47.3 30.0 29.7 18.9 86.4 10.1 3.4 34.0 32.0 36.5 69.9 36.3 19.5 3.9 32.5 41.1 3.9 6.0 46.9 6.0 7.1 68.2 8.3 1.9 30.1 5.1 35.6 11.5 32.6 5.6 15.5 3.7 8.4 5.5 22.1 35.1 7.7 10.9 27.3 35.1 8.1 1.3 15.4 1.8 4.5 2.7 3.0 26.0 35.8 16.3 26.9 2.2 1.0 13.3 11.6 21.2 1.9 16.7 5.0 10.2 2.7 54.5 18.8 4.2 10.6 3.7 5.0 14.6 3.9 12.6 3.9 28.7 5.8 13.9 0.8 69.2 8.3 18.6 12.6 18.4 11.2 22.4 1.2 39.9 86.2 12.6 27.2 30.5 1.2 28.2 6.1 19.5 143.9 11.4 3.1 0.4 3.4 3.8 2.3 27.1 18.1 8.4 2.5 5.9 1.0 1.1 1.6 3.4 9.1 1.5 7.0 12.4 5.6 7.8 1.5 11.9 11.8 9.0 1.1 12.5 0.9 38.1 5.6 4.9 27.8 28.5 32.8 33.9 30.0 29.7 34.0 32.0 32.5 30.1 32.6 35.1 4.0 9.6 43.7 23.5 12.7 1.9 6.2 33.6 5.7 19.2 52.2 38.5 99.4 52.9 36.6 44.1 10.4 72.9 16.3 23.3 17.6 27.1 28.8 17.9 2.6 5.7 59.4 13.7 11.6 27.7 4.6 4.3 31.1 16.5 7.0 482.7 5.0 220.6 15.6 25.2 15.3 21.8 52.9 6.3 2.7 59.3 9.9 5.8 12.4 2.8 9.4 204.7 7.2 17.1 36.5 21.7 23.7 2.2 12.9 31.3 29.0 77.5 37.9 23.6 13.1 1.6 21.8 13.3 17.9 18.0 7.0 82.1 8.3 204.8 19.0 10.4 TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 9.6" "Group enriched" "Detected in many" 6 "Early spermatids: 172.0;Late spermatids: 44.6;Oligodendrocytes: 96.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA029465: AB_10600914" "unprognostic (1.80e-4)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.25e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-5)" "prognostic unfavorable (3.20e-4)" "unprognostic (7.60e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.39e-1)" "unprognostic (1.00e-1)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "prognostic favorable (9.20e-4)" 2.1 0.2 6.0 1.0 15.8 0.3 1.7 12.4 10.6 0.5 0.4 3.8 2.5 0.7 0.6 0.4 0.4 1.4 1.4 7.0 9.0 0.6 0.3 2.9 0.3 13.8 13.2 0.2 0.4 0.4 0.3 4.3 12.6 1.5 4.5 1.1 0.4 0.9 0.9 1.1 2.7 1.1 7.5 0.6 3.1 9.6 15.0 0.2 0.8 0.9 0.2 8.1 0.8 23.9 1.9 3.5 1.0 1.9 0.2 1.6 4.8 0.6 1.0 0.7 1.5 1.2 8.5 0.2 7.9 0.7 1.8 6.8 2.9 2.8 0.9 0.1 2.0 0.1 3.6 5.5 0.2 0.2 0.1 0.3 4.1 6.5 7.2 2.2 2.6 3.8 2.2 0.2 2.8 3.9 0.3 0.3 3.1 11.1 5.1 0.2 3.1 0.2 1.3 8.7 0.6 1.9 2.1 5.4 0.6 4.9 1.7 0.6 2.3 1.1 1.8 1.3 3.3 0.4 0.9 0.2 5.4 0.3 1.0 0.7 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.0 6.0 15.8 12.4 10.6 7.0 9.0 13.8 13.2 12.6 7.5 15.0 23.9 12.6 3.2 6.2 3.9 0.1 0.4 4.4 3.2 0.0 0.6 1.3 0.4 0.7 1.5 2.0 0.0 0.0 0.2 0.0 13.4 0.0 4.1 172.0 1.4 0.4 4.9 1.2 2.7 7.5 11.0 2.3 0.6 9.2 2.4 0.0 1.2 4.6 0.2 0.2 0.0 12.1 6.0 4.1 0.0 1.2 44.6 1.2 0.6 0.0 6.5 0.2 0.3 2.1 6.6 96.5 14.0 8.0 0.4 0.1 2.3 3.6 0.3 0.9 2.7 0.0 1.6 2.2 6.9 12.1 1.9 1.0 0.3 0.4 0.1 7.6 17.3 TMEM120A "NET29, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 289.1;Late spermatids: 1002.1;Proximal enterocytes: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.78e-2)" "unprognostic (3.35e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.26e-1)" "unprognostic (2.75e-3)" "unprognostic (6.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.15e-2)" 54.4 95.0 33.9 11.0 32.7 13.9 44.4 36.9 40.6 33.1 33.2 33.7 50.6 22.6 21.6 31.8 32.0 16.6 111.9 32.3 34.4 38.9 84.7 25.0 10.1 57.6 36.1 56.1 43.2 17.4 20.0 15.6 61.5 26.5 14.8 6.1 24.7 23.3 79.3 18.5 63.4 11.0 31.2 28.2 44.3 77.1 34.7 8.0 19.4 94.4 12.0 32.9 27.3 31.8 10.3 15.3 7.7 61.7 52.1 35.1 16.9 10.0 27.8 13.7 17.2 26.8 14.3 4.8 7.6 30.4 39.1 11.8 7.6 10.3 4.7 9.0 8.5 5.2 10.6 38.2 50.6 2.1 32.6 37.5 9.2 10.1 12.2 14.3 22.4 8.7 9.8 7.9 24.5 18.5 3.3 32.6 3.5 23.7 16.3 3.5 7.8 23.6 28.2 9.3 3.8 18.0 11.4 32.5 16.7 19.1 22.7 15.4 12.8 38.1 12.0 22.1 8.6 8.5 7.0 2.2 20.7 5.3 8.9 106.6 58.0 109.5 26.4 53.7 20.0 15.8 21.7 20.5 27.2 17.9 15.1 14.8 223.0 31.2 55.2 10.7 50.9 46.5 33.9 32.7 36.9 40.6 32.3 34.4 57.6 36.1 61.5 31.2 34.7 31.8 22.4 22.4 12.3 12.7 14.1 0.0 18.1 0.0 18.8 5.6 36.2 22.2 112.7 51.5 8.6 27.6 6.2 20.9 17.6 133.9 25.4 50.3 289.1 9.8 29.3 21.4 8.4 11.4 4.1 38.9 16.2 36.0 31.1 18.1 24.6 172.6 29.3 115.6 36.1 11.8 7.2 40.5 0.0 34.2 0.0 1002.1 40.4 36.0 0.0 3.7 23.7 12.8 18.6 4.0 7.3 40.0 108.9 30.9 24.6 17.4 414.8 118.0 4.4 7.0 39.5 46.0 31.2 113.4 15.4 33.1 0.0 10.9 20.0 31.0 43.6 28.1 TMEM132C "DKFZp761O2018, PPP1R152" ENSG00000181234 "Transmembrane protein 132C" Q8N3T6 12 128267403-128707915 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.6" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 217.3;Microglial cells: 160.2;Oligodendrocyte precursor cells: 580.6" "Group enriched" "Detected in some" 4 "glioma: 1.6;ovarian cancer: 4.6;testis cancer: 4.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "gdT-cell: 1.9" "Lineage enriched" "Detected in single" 19 "T-cells: 1.9" "Group enriched" "Detected in some" 7 "AF22: 3.7;ASC diff: 5.2;Daudi: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015633, HPA015984" Approved Centrosome,Cytosol NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Centrosome, Cytosol" "HPA015633: AB_1858089, HPA015984: AB_1858088" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (7.34e-2)" "unprognostic (8.60e-2)" "unprognostic (2.37e-1)" "unprognostic (1.99e-3)" "unprognostic (5.48e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.85e-2)" "unprognostic (6.29e-2)" "unprognostic (7.97e-3)" "unprognostic (2.54e-1)" "unprognostic (5.71e-2)" "unprognostic (6.33e-3)" 31.6 2.7 8.3 0.3 7.6 0.0 14.0 6.8 7.3 16.8 15.5 1.4 0.3 5.4 3.8 3.1 11.8 1.1 4.3 6.7 7.4 0.4 0.1 1.5 1.1 9.3 14.4 8.6 2.7 0.1 0.7 2.5 8.7 2.4 0.4 3.6 1.7 4.1 0.5 2.0 1.8 1.0 6.7 0.3 1.2 1.3 9.6 1.0 0.9 3.4 0.4 4.7 9.2 6.0 0.0 0.0 3.7 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.6 6.8 7.3 6.7 7.4 9.3 14.4 8.7 6.7 9.6 6.0 1.9 0.0 0.0 70.2 0.0 0.4 0.0 0.0 0.0 18.6 0.0 0.0 1.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 1.1 0.2 7.6 26.1 1.0 0.0 0.0 32.2 0.0 0.0 6.3 0.0 9.8 0.0 3.7 0.0 0.0 0.1 0.0 217.3 0.1 0.0 0.0 1.1 0.2 9.0 0.1 1.8 160.2 0.0 0.4 0.0 580.6 42.3 0.1 0.0 15.1 0.0 0.0 0.1 0.1 0.0 2.3 0.0 0.8 2.5 0.1 0.4 0.1 0.0 0.0 0.3 0.0 0.1 0.0 TMEM213 ENSG00000214128 "Transmembrane protein 213" A2RRL7 7 138797952-138838101 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 76.0;salivary gland: 52.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 53.3;Distal tubular cells: 144.8;Melanocytes: 26.6" "Cancer enriched" "Detected in some" 22 "renal cancer: 21.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 2.1;neutrophil: 1.1;NK-cell: 2.0" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.0" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054059 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA054059: AB_2682361" "unprognostic (2.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (6.84e-2)" "unprognostic (1.17e-2)" "unprognostic (2.10e-1)" "unprognostic (6.14e-2)" "unprognostic (6.08e-2)" "unprognostic (1.91e-2)" "prognostic favorable (5.54e-7)" "unprognostic (4.33e-1)" "unprognostic (9.99e-2)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" 0.1 0.1 0.5 0.2 0.5 1.1 4.7 0.6 0.7 2.8 0.4 0.1 1.3 0.2 0.6 0.3 0.1 0.2 0.0 0.6 0.1 76.0 0.1 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.1 0.3 52.3 1.2 0.1 5.3 0.3 0.1 0.0 0.2 0.4 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 2.1 0.2 0.2 0.3 0.2 0.4 0.2 0.1 0.2 0.1 0.3 0.2 0.1 1.1 2.0 0.2 0.2 0.1 0.1 0.5 0.5 0.6 0.7 0.6 0.1 0.2 0.1 0.4 0.0 0.5 1.0 0.1 3.2 9.9 0.0 0.1 0.0 0.9 3.0 0.0 0.4 14.1 7.9 0.4 0.0 4.4 53.3 0.0 0.0 0.2 0.0 144.8 0.0 0.0 0.9 0.4 0.5 0.0 0.0 0.6 0.2 0.1 0.2 0.0 1.3 1.3 0.1 0.0 0.0 0.1 1.7 0.4 0.0 2.0 0.0 0.8 0.0 0.0 0.1 26.6 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 3.5 1.3 0.0 0.5 0.2 0.0 0.2 0.0 0.4 0.0 0.6 0.0 0.2 0.6 TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 101.1;liver: 100.0;parathyroid gland: 124.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.9;Hepatocytes: 184.5;Muller glia cells: 146.8;Proximal enterocytes: 575.7;Proximal tubular cells: 188.1" "Cancer enhanced" "Detected in all" "renal cancer: 57.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "EFO-21: 26.9;Hep G2: 74.7;RPTEC TERT1: 60.0" "Low region specificity" "Detected in all" HPA053794 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA053794: AB_2682265" "unprognostic (2.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.01e-1)" "unprognostic (4.59e-3)" "unprognostic (2.56e-1)" "unprognostic (9.60e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-1)" "unprognostic (2.83e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-2)" "unprognostic (2.99e-1)" "unprognostic (2.61e-2)" 53.1 11.1 2.1 6.6 2.0 0.7 25.6 1.8 3.6 21.9 2.5 37.3 53.5 6.4 4.8 6.8 3.4 23.2 4.8 1.5 1.8 101.1 100.0 15.4 10.2 2.5 2.1 12.7 13.3 124.7 1.0 14.9 2.3 3.9 19.0 23.6 7.0 7.6 2.4 10.5 76.1 4.8 2.5 25.7 18.1 5.1 3.7 3.0 31.1 4.2 4.9 7.0 5.6 3.2 0.0 7.3 0.7 0.3 4.3 0.4 1.0 0.2 0.1 0.0 0.1 11.4 6.4 0.0 26.9 3.4 0.6 1.7 3.0 0.0 0.0 0.0 2.9 1.0 4.0 74.7 5.9 0.0 0.1 9.7 0.0 0.0 0.0 0.2 5.9 0.0 0.2 10.9 0.0 0.7 0.0 0.8 5.4 0.1 0.2 0.0 0.1 9.9 60.0 4.9 0.9 0.4 0.3 2.9 0.0 5.0 1.2 1.7 3.8 0.0 10.4 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.1 2.0 1.8 3.6 1.5 1.8 2.5 2.1 2.3 2.5 3.7 3.2 12.2 25.6 9.6 0.0 3.2 2.0 0.3 11.1 0.0 2.4 1.8 1.5 2.1 82.9 13.6 18.4 0.0 64.9 0.1 179.9 50.9 36.1 0.3 7.7 98.8 15.1 9.1 5.3 0.0 52.3 3.8 17.9 11.7 10.3 1.3 16.4 61.8 184.5 64.6 6.7 0.0 22.0 14.2 65.5 5.0 1.9 49.7 19.5 1.8 0.0 0.6 146.8 0.0 0.0 0.6 15.3 68.1 3.8 0.0 0.1 575.7 188.1 7.6 17.4 0.0 0.9 14.8 0.0 0.8 1.0 2.8 104.1 2.4 45.3 23.3 2.3 TNFAIP8 "GG2-1, MDC-3.13, SCC-S2" ENSG00000145779 "TNF alpha induced protein 8" O95379 5 119268692-119399688 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.8" "Cell type enhanced" "Detected in many" "granulocytes: 211.8;Langerhans cells: 323.4;Syncytiotrophoblasts: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 155.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054434, HPA057089" Uncertain Enhanced Nucleoplasm No Yes 470000 "Cluster 2: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA054434: AB_2682487, HPA057089: AB_2683331" "prognostic favorable (2.45e-4)" "unprognostic (6.06e-2)" "unprognostic (9.81e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" "unprognostic (1.08e-1)" "unprognostic (2.86e-3)" "unprognostic (4.92e-1)" "unprognostic (1.55e-1)" "unprognostic (4.45e-2)" "unprognostic (5.81e-3)" "unprognostic (4.47e-1)" "unprognostic (1.16e-1)" "unprognostic (1.18e-2)" "unprognostic (1.88e-3)" "unprognostic (1.64e-1)" "unprognostic (1.73e-2)" 72.4 5.1 4.2 62.3 4.1 65.5 19.3 8.9 7.0 15.9 31.2 17.8 16.1 13.3 17.1 25.3 10.5 16.6 8.5 3.9 4.0 16.4 10.1 19.1 117.8 4.9 4.1 3.5 16.8 14.8 1.6 52.5 4.8 18.9 19.0 2.4 11.2 14.4 3.3 31.6 31.3 15.5 1.7 61.1 28.6 17.5 5.1 100.0 25.3 5.6 115.9 43.6 17.8 6.6 27.7 19.0 10.0 16.1 20.5 17.2 91.2 15.0 40.4 11.1 23.0 10.2 31.6 51.0 4.7 16.7 17.6 38.4 8.3 45.4 15.7 56.6 17.9 81.4 41.1 17.6 9.9 99.6 86.4 19.1 42.0 33.7 15.9 21.2 15.4 99.9 32.0 155.2 15.5 10.7 84.5 128.9 15.0 16.0 8.9 25.6 44.1 75.8 44.5 54.8 5.1 7.8 56.6 10.9 5.5 32.1 9.4 111.4 8.1 20.2 7.8 14.1 17.9 76.0 90.0 103.3 23.3 104.8 11.9 491.9 96.1 305.0 111.0 105.1 217.3 267.2 221.9 164.7 133.6 243.5 260.8 169.7 54.6 111.4 86.7 63.8 188.4 213.0 4.2 4.1 8.9 7.0 3.9 4.0 4.9 4.1 4.8 1.7 5.1 6.6 8.9 9.6 18.7 1.6 174.9 160.5 80.9 81.9 123.5 0.2 14.4 10.8 10.3 12.8 38.3 18.4 0.0 142.6 83.6 2.7 17.6 55.4 4.4 11.8 7.8 23.2 1.2 34.5 0.8 101.0 158.8 30.1 17.9 9.5 211.8 0.7 6.4 1.9 48.9 0.0 2.3 9.9 20.3 59.4 323.4 1.4 2.1 126.0 37.4 24.4 196.6 4.3 111.2 1.0 6.8 125.7 2.7 1.9 45.6 63.9 0.9 19.8 47.2 0.4 46.0 4.0 32.9 1.1 18.0 93.1 119.2 292.7 139.0 35.2 4.3 103.6 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 4 "Plasma cells: 449.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cell line enhanced" "Detected in some" "Karpas-707: 179.6;RPMI-8226: 296.0;U-266/70: 829.4;U-266/84: 453.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" 0.4 1.1 0.0 14.9 0.3 1.9 14.1 0.4 0.4 1.4 0.0 28.9 29.0 0.5 0.2 1.9 0.6 3.1 0.4 0.2 0.3 0.3 1.0 2.0 31.9 0.3 0.0 0.8 0.5 0.1 0.1 0.1 0.3 0.4 22.1 0.1 15.4 0.9 0.0 0.3 15.2 0.6 0.0 20.3 24.4 2.2 0.3 14.8 0.7 0.1 47.9 9.9 0.3 0.6 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.8 0.3 0.1 0.0 0.0 49.2 0.1 0.3 0.1 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 179.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.6 0.0 296.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 0.6 0.0 0.5 0.5 0.0 0.5 829.4 453.4 68.1 0.7 0.2 0.0 1.2 0.4 0.2 0.3 0.1 0.4 124.9 0.2 0.2 0.2 108.5 0.1 0.2 1.8 0.7 0.1 103.3 0.1 12.6 0.0 0.3 0.4 0.4 0.2 0.3 0.3 0.0 0.3 0.0 0.3 0.6 0.0 0.0 0.0 0.0 91.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 10.9 0.0 0.0 0.7 0.0 5.3 0.1 0.0 0.0 0.4 2.0 0.0 0.0 0.4 1.8 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 106.7 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 449.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.7 0.6 0.0 0.6 0.0 6.0 0.0 1.0 0.0 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.3" "Cell type enhanced" "Detected in some" "Adipocytes: 7.1;Early spermatids: 3.5;Kupffer cells: 5.3;Langerhans cells: 3.3;Late spermatids: 9.8;Macrophages: 5.8;monocytes: 5.1" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 96.6" "Lineage enriched" "Detected in many" 5 "monocytes: 96.6" "Cell line enriched" "Detected in some" 21 "HDLM-2: 552.9" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" 5.3 0.0 0.1 3.1 2.3 0.6 3.5 0.0 0.6 0.2 0.1 0.4 0.0 0.8 0.0 0.2 0.9 0.6 1.9 0.0 0.2 0.3 0.0 0.9 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.7 0.2 0.2 0.1 0.0 0.3 0.1 0.9 0.9 0.7 0.5 0.1 1.4 2.5 1.4 0.7 1.0 0.1 1.2 1.1 0.9 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.4 0.0 0.1 0.8 11.7 0.0 0.0 0.0 0.0 0.0 0.1 552.9 0.1 0.0 0.1 0.0 0.0 10.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.7 26.3 1.5 0.0 0.0 1.5 0.2 21.7 0.0 0.4 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 1.4 1.4 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 17.6 1.0 0.1 59.4 0.3 0.1 0.1 0.0 8.7 0.0 0.0 0.0 18.3 0.0 96.6 2.3 0.8 8.5 0.1 2.3 0.0 0.6 0.0 0.2 0.2 0.1 0.2 0.1 0.7 0.2 7.1 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.1 0.5 2.2 0.0 0.0 0.6 0.0 0.2 1.1 2.6 0.1 0.0 0.1 2.2 0.1 1.5 0.0 0.5 0.0 0.0 5.3 3.3 9.8 0.3 5.8 0.0 1.0 5.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 1.0 0.0 0.1 0.3 0.4 0.2 0.0 0.1 TP53I13 DSCP1 ENSG00000167543 "Tumor protein p53 inducible protein 13" Q8NBR0 17 29566052-29573157 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 110.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.93e-1)" "unprognostic (4.90e-2)" "unprognostic (2.50e-3)" "unprognostic (9.31e-3)" "unprognostic (4.94e-3)" "unprognostic (1.05e-2)" "unprognostic (2.17e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (5.47e-2)" "prognostic favorable (3.13e-5)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (2.92e-2)" 71.2 34.7 19.5 30.3 20.4 37.4 58.5 18.6 28.3 41.8 26.2 50.0 45.1 36.8 5.6 31.1 35.5 19.5 53.1 17.7 18.7 68.2 111.3 50.2 42.4 23.6 21.3 33.1 47.2 15.7 91.8 13.5 21.8 43.1 8.9 1.5 35.6 14.4 30.1 29.0 79.1 10.3 19.6 78.1 48.1 60.5 21.0 11.7 58.0 11.0 16.2 41.9 38.6 22.4 27.9 73.9 22.2 64.0 37.0 25.4 41.0 45.6 20.5 27.2 29.2 31.3 11.1 19.3 49.1 27.9 38.5 66.8 10.4 13.4 3.9 84.2 41.3 11.8 85.0 29.0 33.0 19.7 34.5 21.9 19.0 23.9 8.4 18.5 16.6 39.6 17.3 34.8 12.1 45.4 48.7 79.1 9.8 32.4 28.1 91.0 53.4 69.0 24.9 17.8 10.0 32.5 56.9 21.0 22.4 8.1 60.7 81.5 19.1 26.9 40.6 28.9 36.2 71.7 33.9 15.8 47.5 11.9 32.4 52.6 11.2 20.8 26.5 14.5 26.4 24.1 25.4 20.1 26.0 23.4 19.8 17.9 0.9 28.8 9.7 110.9 25.0 13.6 19.5 20.4 18.6 28.3 17.7 18.7 23.6 21.3 21.8 19.6 21.0 22.4 19.5 0.0 3.0 16.3 31.2 13.8 42.4 48.1 25.6 0.8 28.2 38.9 28.1 12.8 23.2 40.5 6.2 50.8 47.7 30.2 7.9 33.9 17.9 19.7 32.4 14.1 19.9 9.0 5.6 28.7 40.0 47.5 30.1 28.1 15.9 33.9 13.2 22.1 27.4 6.7 4.0 28.6 24.4 10.7 31.2 8.4 34.5 28.9 30.2 18.7 23.1 20.0 12.3 3.5 5.6 27.4 31.7 18.8 31.8 30.6 51.9 17.7 16.2 9.0 19.7 31.9 26.0 87.8 33.4 13.9 7.4 22.6 30.4 23.9 27.1 37.6 TRARG1 "BEC-1, DSPB1, IFITMD3, LOST1, TUSC5" ENSG00000184811 "Trafficking regulator of GLUT4 (SLC2A4) 1" Q8IXB3 17 1279662-1300978 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "adipose tissue: 101.4;breast: 68.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 294 "ASC diff: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050825 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050825: AB_2681252" "unprognostic (5.84e-2)" "unprognostic (7.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (2.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (1.90e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (5.10e-1)" 101.4 1.1 0.0 1.2 0.0 0.0 68.7 0.0 0.4 0.4 0.0 1.2 0.0 0.2 0.0 0.1 0.1 0.6 1.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 1.2 2.1 2.3 0.0 0.0 0.0 0.6 0.6 0.0 0.1 1.0 0.6 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 10 "dendritic cells: 338.0;NK-cells: 580.9;T-cells: 399.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cell line enriched" "Detected in some" 5 "JURKAT: 1467.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" 9.2 5.1 1.3 140.0 1.5 53.5 9.5 1.1 2.1 7.7 1.5 18.5 26.8 6.4 5.7 12.0 7.0 26.7 5.0 1.0 1.1 5.4 11.4 31.5 322.2 2.0 1.2 6.4 2.7 0.9 2.0 2.3 1.7 9.0 19.4 0.0 19.0 4.6 1.0 9.9 49.7 4.2 1.7 92.5 27.1 2.7 1.6 1520.1 8.4 2.1 227.0 33.2 6.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 1467.5 2.0 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 296.5 2.0 0.0 1.9 0.0 45.6 7.2 4.7 869.6 3.5 693.8 17.1 1893.1 1259.3 5.8 15.7 1989.8 1450.7 37.3 359.8 8.3 9.7 3232.4 1917.5 1.3 1.5 1.1 2.1 1.0 1.1 2.0 1.2 1.7 1.7 1.6 1.9 7.3 19.2 40.8 0.0 11.7 0.0 0.3 0.0 0.0 0.0 5.9 5.5 0.0 0.0 3.1 1.8 0.0 0.2 338.0 0.0 0.0 0.5 0.6 1.1 0.7 1.5 0.0 10.7 0.0 0.0 0.1 3.2 4.6 0.8 20.2 0.0 5.3 1.5 0.3 0.0 0.0 0.1 0.0 8.4 0.0 1.9 17.4 13.9 0.0 0.0 17.3 0.0 580.9 0.0 0.0 0.0 0.1 8.2 23.6 0.3 0.0 2.4 0.7 0.0 0.0 1.1 3.5 0.0 0.1 0.5 0.0 0.1 399.0 0.1 0.1 0.4 TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 164.7;dendritic cells: 358.8;NK-cells: 264.7;T-cells: 498.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cell line enriched" "Detected in some" 45 "MOLT-4: 277.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" 18.9 3.1 0.4 3.9 0.3 1.5 8.6 0.1 1.2 11.9 0.1 21.2 1.7 8.7 0.0 14.6 15.7 2.2 4.9 0.3 0.0 9.6 12.7 32.3 8.6 0.2 0.3 18.3 3.5 0.1 4.0 0.0 0.2 14.2 2.7 0.0 7.9 0.1 3.3 6.5 115.8 0.5 0.1 190.2 16.9 8.7 0.3 109.2 16.4 1.2 10.9 14.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 3.5 0.0 0.0 0.0 0.0 277.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 35.0 8.1 47.6 47.3 0.3 7.7 46.6 40.3 2.0 10.5 0.1 0.0 76.0 42.4 0.4 0.3 0.1 1.2 0.3 0.0 0.2 0.3 0.2 0.1 0.3 0.1 8.3 9.6 52.4 0.0 164.7 0.0 0.3 0.0 1.8 0.1 6.2 9.7 4.8 5.7 3.7 1.8 0.0 0.4 358.8 1.4 0.0 2.9 1.0 1.1 0.8 4.0 0.0 16.6 0.0 1.3 0.1 10.8 8.6 0.9 20.2 0.0 15.0 1.6 0.4 0.0 0.0 0.8 0.0 9.0 0.0 4.2 63.6 18.9 0.0 0.0 19.0 15.6 264.7 0.0 0.0 20.1 0.1 70.3 30.6 0.4 0.1 2.2 2.9 0.4 65.7 4.2 12.4 0.1 0.8 1.3 0.0 0.3 498.0 1.4 0.9 0.2 TRHDE "PAP-II, PGPEP2, TRH-DE" ENSG00000072657 "Thyrotropin releasing hormone degrading enzyme" Q9UKU6 12 72087266-72670758 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;pancreas: 10.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 216.9;Inhibitory neurons: 292.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.9" "Group enriched" "Detected in many" 5 "basal ganglia: 4.9;cerebellum: 4.4;cerebral cortex: 2.5;hippocampal formation: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 30.3;BJ hTERT+: 29.1;EFO-21: 15.3;HBF TERT88: 10.3;hTERT-RPE1: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 7300000 "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.56e-2)" "unprognostic (4.06e-3)" "unprognostic (6.01e-2)" "unprognostic (1.44e-6)" "unprognostic (1.77e-1)" "unprognostic (6.37e-2)" "unprognostic (7.79e-2)" "unprognostic (6.96e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (5.14e-4)" "unprognostic (2.40e-1)" "prognostic favorable (1.53e-7)" "unprognostic (2.55e-2)" "unprognostic (2.48e-1)" "unprognostic (8.91e-3)" "unprognostic (2.94e-2)" 3.6 0.9 0.1 0.3 4.9 0.4 0.8 4.4 2.5 3.7 0.0 1.1 2.4 1.2 0.6 0.2 1.1 0.8 0.8 7.6 0.0 5.1 0.5 1.4 0.1 0.0 0.9 3.2 10.3 0.0 0.1 0.1 0.0 1.3 0.5 0.8 0.8 2.8 0.2 0.2 2.1 0.4 0.0 2.5 0.3 0.7 0.0 0.1 0.0 0.4 0.3 1.2 2.3 0.0 3.6 0.0 0.6 0.0 1.6 0.0 9.5 30.3 29.1 2.9 1.9 0.0 0.0 0.0 15.3 4.3 3.0 0.4 5.4 0.0 10.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 2.3 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.7 0.0 0.0 0.0 9.5 6.7 2.9 0.1 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.9 4.4 2.5 7.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.5 2.9 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 1.5 0.0 1.8 0.0 0.1 0.0 7.1 3.9 0.0 35.9 0.1 0.4 0.2 0.0 0.0 216.9 2.6 0.4 4.7 0.0 0.3 0.0 0.1 0.4 1.4 0.2 0.0 292.7 3.5 0.0 0.0 0.0 62.8 29.5 0.7 0.0 2.8 0.0 0.4 0.0 38.2 4.0 2.2 3.9 13.5 0.0 0.2 15.8 9.1 0.7 0.6 0.0 37.4 0.6 0.2 0.7 0.0 0.0 0.1 0.1 0.2 1.6 0.1 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 104.3;Muller glia cells: 100.3" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.8" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.8" "Cell line enhanced" "Detected in many" "AN3-CA: 183.5;HEL: 185.7;K-562: 258.0;SK-MEL-30: 189.3;WM-115: 246.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 43.3 63.1 29.1 38.9 29.9 16.8 38.3 36.1 35.2 21.7 30.5 27.0 17.8 44.4 43.4 15.5 23.4 28.8 51.0 31.6 37.7 92.3 21.0 39.8 72.7 31.4 30.8 97.8 26.2 18.0 20.0 46.6 29.7 33.0 13.4 137.8 20.4 25.6 14.3 16.9 25.2 34.2 29.7 79.7 41.8 28.5 32.4 39.3 23.9 19.5 69.6 48.4 19.5 28.0 0.2 0.4 138.8 183.5 48.9 44.7 0.2 7.9 7.5 4.9 7.9 0.9 15.3 16.3 5.5 16.9 0.8 2.3 10.3 16.1 4.2 18.3 28.9 185.7 0.4 2.7 60.7 10.7 68.0 41.7 16.0 20.3 5.6 48.9 22.1 23.8 258.0 0.3 7.9 1.7 24.4 44.8 66.1 7.0 18.0 0.0 46.2 6.7 31.9 23.4 118.9 56.6 1.1 7.4 189.3 41.4 0.2 1.1 13.9 65.3 32.0 0.6 17.8 0.1 0.2 22.9 35.2 36.3 246.7 1.7 0.2 3.2 12.7 0.0 15.8 9.6 26.1 13.8 1.2 12.2 15.0 9.2 0.5 19.3 0.2 0.1 48.8 8.9 29.1 29.9 36.1 35.2 31.6 37.7 31.4 30.8 29.7 29.7 32.4 28.0 52.2 3.2 8.3 25.5 12.5 6.1 9.1 26.9 19.4 55.0 7.9 8.6 17.1 12.8 15.6 16.5 31.3 2.6 17.5 0.7 7.9 17.2 4.3 9.7 11.6 43.9 0.0 22.1 13.5 104.3 0.2 11.3 20.9 15.9 34.2 77.3 59.6 6.7 5.8 20.2 6.9 0.4 28.5 5.1 8.2 14.3 77.3 3.8 30.2 13.1 3.0 100.3 26.8 59.8 2.7 45.3 0.2 74.4 21.0 11.6 0.3 1.0 17.9 66.7 52.6 9.9 41.2 1.0 6.0 5.7 5.4 0.8 27.1 30.5 0.8 32.5 TRIM61 RNF35 ENSG00000183439 "Tripartite motif containing 61" Q5EBN2 4 164954446-164977668 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 34.5;Late spermatids: 14.0;Spermatocytes: 50.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 15.1;SuSa: 10.2;U-266/70: 17.2" "Not detected" "Not detected" HPA049109 Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA049109: AB_2680636" "unprognostic (2.05e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (1.02e-2)" "unprognostic (8.24e-2)" "unprognostic (1.51e-2)" "unprognostic (1.38e-1)" "unprognostic (2.98e-2)" "unprognostic (7.81e-2)" "unprognostic (1.51e-1)" "unprognostic (3.67e-1)" "unprognostic (2.92e-1)" "unprognostic (9.77e-5)" "unprognostic (4.61e-2)" "unprognostic (2.51e-1)" "unprognostic (1.36e-1)" "unprognostic (4.32e-2)" 2.1 3.6 1.9 2.2 2.2 3.7 1.3 2.2 2.3 2.9 0.3 1.3 1.9 1.5 2.1 1.0 3.5 2.9 3.0 1.8 3.1 1.0 1.1 2.2 3.2 2.4 2.6 5.0 1.4 1.1 1.0 1.7 2.3 1.8 1.4 2.7 0.9 2.0 0.9 1.1 1.4 2.2 1.7 2.1 1.3 8.9 2.5 2.6 5.6 1.4 2.9 2.3 0.2 2.7 0.9 0.8 2.0 2.1 1.1 1.1 1.2 4.2 1.3 0.9 0.8 0.7 1.4 0.9 1.1 5.3 1.0 1.0 1.4 1.5 0.9 1.6 0.8 1.6 1.5 0.9 15.1 1.6 1.4 9.0 1.3 3.7 1.4 8.5 0.8 1.3 1.8 3.6 0.8 1.0 1.4 1.0 6.5 1.0 0.7 1.4 1.1 1.2 0.6 2.6 1.7 1.1 1.0 1.5 1.2 10.2 0.5 1.6 0.9 2.7 1.8 0.9 1.7 17.2 8.2 2.3 1.0 0.9 1.9 5.4 1.4 0.1 2.9 1.2 3.3 3.5 1.8 3.3 1.5 5.8 4.4 3.6 0.3 8.0 1.1 4.1 0.8 1.4 1.9 2.2 2.2 2.3 1.8 3.1 2.4 2.6 2.3 1.7 2.5 2.7 0.2 0.0 3.3 1.0 3.8 0.3 1.2 0.4 0.0 1.1 0.1 0.1 2.3 0.0 0.2 3.7 4.2 0.3 2.3 0.0 0.0 0.3 34.5 0.4 2.1 0.9 0.0 1.3 1.9 0.7 0.0 1.6 0.5 0.1 0.0 4.8 0.0 0.4 1.1 1.7 1.4 0.0 0.0 0.6 0.7 14.0 1.2 0.9 0.0 0.0 1.7 2.7 1.0 3.5 4.3 0.1 0.1 1.5 6.4 0.6 0.0 3.7 0.1 0.4 0.0 1.5 1.3 50.1 3.7 0.2 0.0 0.3 2.2 2.8 0.0 0.6 TRIM67 TNL ENSG00000119283 "Tripartite motif containing 67" Q6ZTA4 1 231162112-231221556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 8.5;retina: 3.5" "Group enriched" "Detected in some" 4 "Horizontal cells: 69.0;Inhibitory neurons: 24.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034776 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA034776: AB_10603997" "unprognostic (1.56e-3)" "unprognostic (1.54e-1)" "unprognostic (5.20e-2)" "unprognostic (5.39e-3)" "unprognostic (2.95e-1)" "unprognostic (3.82e-2)" "unprognostic (6.02e-2)" "unprognostic (4.63e-3)" "unprognostic (1.84e-2)" "unprognostic (1.74e-1)" "unprognostic (4.93e-10)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (4.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.30e-2)" "unprognostic (5.10e-3)" 0.0 0.2 1.0 0.0 0.8 0.0 0.0 8.5 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.4 1.5 0.0 0.0 0.0 0.0 3.5 1.5 0.0 0.0 0.0 0.5 0.1 2.7 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 8.5 2.2 1.4 1.5 3.5 1.5 2.7 1.7 1.5 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.0 24.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.5 0.0 6.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 237.3" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 506.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 168.0;ASC diff: 282.5;OE19: 188.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" NA NA 6200000 "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nuclear bodies" "HPA008164: AB_1853327" "unprognostic (1.07e-2)" "unprognostic (2.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (3.66e-4)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (4.81e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (2.87e-4)" "prognostic favorable (1.66e-4)" "prognostic unfavorable (2.80e-8)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (6.71e-2)" "unprognostic (3.88e-2)" 96.5 12.1 4.2 8.3 4.5 2.1 80.4 6.5 5.8 147.1 27.8 23.5 37.1 46.4 20.6 62.8 67.7 14.9 34.8 6.5 2.7 41.5 237.3 15.0 2.4 4.4 3.1 47.0 16.8 6.4 14.8 30.3 5.0 44.0 14.4 4.1 33.9 24.6 9.5 60.0 32.3 41.1 1.9 6.9 28.2 9.1 3.9 4.7 37.6 5.7 5.6 41.6 99.6 4.4 3.7 168.0 19.1 18.4 282.5 36.1 34.6 5.9 32.2 12.6 12.0 22.2 48.0 0.3 32.7 21.1 53.7 68.6 10.9 42.7 3.9 35.7 5.9 8.3 43.5 63.1 53.6 3.0 11.9 37.3 46.0 22.5 18.2 24.0 15.7 6.4 19.9 1.4 11.7 81.9 0.5 6.5 24.5 188.9 7.4 5.9 18.3 28.7 29.7 29.7 16.8 28.5 32.7 25.7 15.4 15.8 34.5 2.7 4.9 35.4 28.2 86.8 14.2 1.1 0.6 1.4 16.6 8.9 6.4 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 4.2 4.5 6.5 5.8 6.5 2.7 4.4 3.1 5.0 1.9 3.9 4.4 6.2 0.0 0.5 1.0 0.5 17.3 12.1 25.8 27.9 3.5 13.6 13.2 3.2 11.5 12.1 1.8 0.0 50.0 0.1 33.2 0.0 6.7 0.2 8.1 35.6 5.8 7.8 13.5 0.5 21.7 71.8 33.0 14.8 10.6 1.3 38.7 9.7 506.3 9.9 0.0 0.1 12.4 26.4 9.1 6.4 2.0 37.3 0.8 5.4 1.9 1.6 9.2 0.0 0.0 0.0 21.3 21.2 45.1 0.1 14.6 28.6 21.9 3.0 0.6 0.0 1.0 11.3 0.4 2.0 22.3 22.6 43.8 1.6 8.6 13.8 20.1 TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 705.9;Muller glia cells: 508.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 481.0;naive B-cell: 488.1;plasmacytoid DC: 313.2" "Group enriched" "Detected in all" 5 "B-cells: 488.1;dendritic cells: 313.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" 333.8 143.9 257.2 87.3 248.9 33.3 143.3 253.4 292.4 138.2 288.7 364.2 342.1 130.9 432.8 78.4 249.8 186.2 108.8 247.8 296.3 211.3 87.4 202.1 88.0 250.0 267.7 148.1 140.2 283.4 189.7 111.6 260.2 96.2 386.3 418.6 152.2 187.3 429.1 78.3 349.2 128.3 266.7 84.8 221.2 84.8 282.5 71.6 200.3 374.4 106.9 170.1 67.4 281.3 130.6 347.6 282.8 179.3 484.7 295.8 93.3 203.7 220.2 245.1 265.7 213.5 264.7 126.9 294.8 211.6 234.0 289.0 271.2 139.5 182.9 143.4 410.4 91.0 252.5 204.4 234.5 118.4 64.3 280.9 165.5 135.8 120.1 372.6 304.8 83.1 98.0 109.2 243.3 49.5 105.7 112.1 200.5 414.7 152.4 130.8 351.0 135.3 408.0 73.0 255.0 282.1 139.8 116.9 393.7 269.3 125.0 220.8 292.1 225.7 88.4 138.0 290.7 237.4 346.6 67.1 200.1 173.5 131.9 8.8 51.3 10.4 32.6 69.6 34.1 481.0 16.5 23.9 99.2 488.1 42.6 39.3 4.8 60.3 77.1 313.2 4.6 95.2 257.2 248.9 253.4 292.4 247.8 296.3 250.0 267.7 260.2 266.7 282.5 281.3 76.1 112.2 213.4 69.5 83.8 34.7 77.5 114.6 36.5 247.7 43.6 32.3 98.2 108.7 169.0 68.0 183.5 89.9 41.3 705.9 25.4 250.2 28.5 86.1 63.4 57.6 91.3 19.4 47.8 354.0 35.6 90.8 85.1 41.7 23.4 88.6 53.6 29.5 65.4 127.9 54.3 290.4 97.6 58.0 27.5 57.9 64.3 38.2 72.9 29.0 35.1 508.9 36.0 116.6 32.7 245.1 410.7 51.6 81.2 220.1 364.3 65.5 201.7 185.1 26.3 44.8 189.0 108.0 64.6 34.2 34.2 75.9 19.4 149.5 205.2 381.4 TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 542.1" "Cell type enhanced" "Detected in many" "Astrocytes: 274.9;Excitatory neurons: 215.6;Hepatic stellate cells: 407.3;Inhibitory neurons: 249.8;Oligodendrocyte precursor cells: 353.4" "Cancer enhanced" "Detected in all" "glioma: 71.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 109.5;JURKAT: 380.9;MOLT-4: 239.7;SCLC-21H: 129.0;U-266/70: 163.2" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB062566: AB_2665608, CAB068245: AB_2665609, HPA003140: AB_1078454" "unprognostic (1.12e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.06e-2)" "unprognostic (3.90e-3)" "unprognostic (3.88e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.54e-1)" "prognostic favorable (5.48e-7)" "unprognostic (5.65e-3)" "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" 56.1 125.6 355.5 17.2 433.8 1.3 33.5 369.5 542.1 42.6 271.3 68.1 36.3 43.8 37.6 33.6 36.5 25.8 70.3 413.7 334.3 56.2 45.0 67.4 41.1 290.3 298.8 19.6 19.8 13.9 28.0 25.1 283.6 18.8 64.6 286.9 12.5 26.8 153.9 19.4 34.0 51.1 291.7 96.3 14.5 4.8 331.7 15.7 51.3 232.3 28.9 29.7 16.9 384.6 0.1 0.0 2.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 3.8 1.6 0.0 109.5 14.9 0.5 0.0 67.2 0.0 0.1 1.2 1.5 0.0 0.0 0.0 0.0 0.0 380.9 0.0 0.4 1.7 0.4 239.7 0.0 11.2 0.1 0.0 14.6 4.6 0.0 11.0 1.4 129.0 14.4 0.0 0.0 4.3 6.5 0.0 0.3 0.0 0.1 3.1 0.1 1.0 163.2 54.8 0.0 5.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 355.5 433.8 369.5 542.1 413.7 334.3 290.3 298.8 283.6 291.7 331.7 384.6 116.1 12.8 23.8 274.9 1.1 10.6 2.7 6.3 6.2 92.0 1.0 3.8 34.1 1.5 4.6 11.0 43.8 0.4 0.2 69.1 23.5 0.4 0.0 2.1 1.6 153.3 18.7 5.3 215.6 0.6 0.4 14.0 4.6 5.6 10.1 108.1 407.3 4.8 45.1 97.6 249.8 23.5 0.0 15.0 10.0 1.9 0.6 1.5 14.2 46.9 0.0 102.3 0.0 353.4 50.6 0.9 21.9 3.0 1.5 2.4 40.3 9.8 1.2 107.4 59.2 26.5 11.7 0.6 3.3 9.9 6.5 0.8 2.6 27.0 35.7 0.9 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;ovary: 49.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.4;Leydig cells: 44.4;Oligodendrocyte precursor cells: 29.1;Oligodendrocytes: 46.8;Peritubular cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 17000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 21.5 3.5 18.2 1.4 30.3 0.8 5.2 17.7 27.1 2.1 0.0 2.3 1.6 4.6 3.5 13.1 11.5 2.5 2.2 27.7 10.7 11.3 0.8 3.3 1.3 20.9 22.6 49.7 9.8 0.9 0.9 5.7 18.6 2.6 0.9 2.6 1.9 6.1 0.9 13.8 2.4 4.4 14.4 5.5 3.2 18.8 15.7 0.4 1.1 1.8 3.7 2.1 4.1 32.0 10.3 6.7 20.7 22.7 18.9 12.8 69.2 14.6 9.3 14.2 13.1 37.7 3.4 0.4 18.3 11.9 19.9 23.7 23.3 3.6 6.5 5.8 15.5 3.2 20.2 18.1 13.3 5.2 0.4 4.1 7.3 10.9 3.6 5.8 10.6 9.8 19.1 4.3 7.9 9.8 2.4 1.0 47.7 16.0 6.7 31.9 18.6 3.8 1.2 19.7 24.6 7.0 13.7 21.6 16.3 29.8 17.8 6.0 8.4 28.0 12.2 21.0 22.5 1.7 3.5 3.1 17.2 33.8 17.2 1.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.2 0.2 1.5 0.3 0.1 0.3 0.1 0.1 18.2 30.3 17.7 27.1 27.7 10.7 20.9 22.6 18.6 14.4 15.7 32.0 3.4 3.2 1.1 17.6 0.9 6.8 8.5 0.4 0.6 2.7 2.2 2.2 2.9 2.8 0.7 3.7 6.2 2.9 1.1 1.3 0.0 3.9 3.6 1.1 13.0 5.4 1.8 0.0 42.4 3.6 10.2 10.5 8.6 1.9 0.0 7.6 9.7 0.4 1.2 0.0 4.6 0.9 0.0 1.9 1.3 5.1 44.4 0.9 8.8 1.0 0.1 8.3 1.0 29.1 46.8 4.6 0.1 47.0 0.3 6.4 1.2 1.2 0.5 4.0 0.0 3.9 4.3 4.0 6.5 4.2 10.9 18.9 0.7 5.8 2.3 5.7 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.9;Muller glia cells: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 209.8 82.0 45.7 12.0 51.3 3.9 151.3 41.8 53.1 103.6 48.2 151.5 12.1 99.9 7.2 50.8 72.5 19.2 253.3 38.7 45.1 84.6 44.0 82.5 14.4 54.8 47.4 82.6 84.9 18.3 104.2 9.8 45.0 92.7 4.7 12.7 57.7 28.5 143.8 77.3 59.5 10.2 44.2 55.9 89.2 17.5 50.6 6.6 83.7 51.5 9.1 118.0 77.5 37.3 15.4 25.9 9.9 28.1 49.7 36.8 12.7 14.7 27.8 13.1 16.0 13.8 31.7 19.8 28.6 14.0 28.8 20.8 15.8 11.5 2.3 20.6 15.1 16.7 33.9 13.3 45.4 4.8 20.1 39.6 12.0 19.6 12.2 33.9 18.4 20.6 20.2 32.5 22.2 31.8 27.4 12.6 7.0 10.9 22.3 32.1 20.5 46.5 11.0 19.5 14.0 46.4 12.4 38.1 57.4 7.6 25.1 5.6 13.0 50.8 30.2 23.1 8.7 90.5 45.5 15.4 41.6 5.3 25.1 0.3 0.2 0.6 0.9 0.0 0.8 3.0 0.8 0.9 0.4 2.4 0.9 1.6 0.0 0.4 0.0 30.5 0.5 0.4 45.7 51.3 41.8 53.1 38.7 45.1 54.8 47.4 45.0 44.2 50.6 37.3 54.1 19.2 32.6 43.8 27.6 12.7 6.7 10.1 2.2 47.9 32.8 65.7 204.9 10.0 7.6 14.7 33.3 9.6 68.3 11.9 39.2 14.8 1.1 24.2 47.7 21.9 53.3 4.4 7.3 12.9 16.8 68.6 5.1 31.6 18.4 62.7 19.6 9.8 51.4 65.6 26.6 12.2 20.3 31.5 21.5 3.5 60.9 50.0 35.6 19.7 17.7 130.6 12.3 29.1 11.8 14.5 7.3 109.1 12.3 11.5 20.3 31.6 8.9 39.6 6.6 47.4 53.7 0.5 1.2 6.4 13.9 8.9 19.0 34.3 12.8 7.5 VKORC1L1 ENSG00000196715 "Vitamin K epoxide reductase complex subunit 1 like 1" Q8N0U8 7 65873074-65959563 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053954 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA053954: AB_2682319" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (4.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-3)" "unprognostic (7.15e-3)" "unprognostic (1.30e-3)" "unprognostic (8.84e-3)" "unprognostic (5.12e-2)" "unprognostic (5.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.07e-1)" "unprognostic (1.59e-2)" "unprognostic (1.17e-1)" "unprognostic (7.03e-3)" "unprognostic (4.30e-1)" "unprognostic (5.06e-2)" 54.0 11.1 8.1 11.2 9.0 4.3 23.7 8.3 12.1 12.0 3.7 12.4 11.1 12.3 10.6 12.5 10.0 10.0 12.1 10.1 9.2 10.0 22.9 18.4 8.7 18.1 10.5 17.3 9.7 33.6 6.7 12.0 10.5 12.0 12.5 11.5 10.9 12.4 21.6 12.8 11.6 11.6 8.9 7.4 12.8 9.1 8.5 9.7 13.9 15.3 8.7 11.9 9.6 9.6 46.8 29.5 23.4 29.5 72.6 28.6 42.3 49.5 31.8 29.0 29.1 28.7 44.9 40.4 39.0 35.7 43.9 31.2 33.6 20.1 47.9 25.5 33.1 27.6 25.4 24.7 35.4 38.7 20.3 23.2 25.3 29.5 40.7 22.5 29.2 22.6 59.0 30.0 34.9 18.3 31.8 44.8 56.1 43.8 22.0 34.5 34.0 50.5 28.0 18.5 28.0 39.8 38.3 68.5 21.8 32.8 34.5 29.5 33.3 46.6 32.0 29.5 51.0 26.9 47.1 46.1 28.6 43.0 41.6 2.0 1.1 2.7 1.2 1.1 1.0 1.3 1.5 1.4 1.3 1.1 0.9 0.9 1.3 2.9 2.2 3.5 1.5 0.7 8.1 9.0 8.3 12.1 10.1 9.2 18.1 10.5 10.5 8.9 8.5 9.6 19.5 73.7 41.7 16.6 5.5 24.9 18.6 16.2 9.6 21.8 18.6 15.9 21.5 27.1 24.2 16.5 12.5 12.5 10.0 27.1 5.9 18.1 39.0 13.7 23.8 17.1 13.8 26.1 42.7 24.8 21.2 22.6 19.4 25.3 5.1 24.1 10.8 46.9 16.0 30.3 36.6 26.4 20.3 6.6 10.2 9.1 17.7 12.9 7.2 28.1 10.0 11.6 7.2 26.7 34.6 31.6 8.2 18.4 15.6 36.3 14.4 11.4 11.7 20.2 6.6 24.9 26.4 18.5 7.2 17.9 32.0 8.8 6.6 10.8 20.3 22.6 VTI1B VTI2 ENSG00000100568 "Vesicle transport through interaction with t-SNAREs 1B" Q9UEU0 14 67647085-67674820 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 493.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044121, HPA048150, HPA060118" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA044121: AB_2678819, HPA048150: AB_2680288, HPA060118: AB_2684206" "unprognostic (2.26e-1)" "unprognostic (4.83e-2)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (3.00e-2)" "unprognostic (2.36e-3)" "unprognostic (3.25e-3)" "unprognostic (9.12e-2)" "unprognostic (1.90e-2)" "unprognostic (3.86e-1)" "unprognostic (2.60e-1)" "unprognostic (2.11e-2)" "prognostic favorable (3.53e-12)" "unprognostic (8.35e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (8.02e-3)" 53.8 26.9 55.5 20.4 56.8 22.3 39.8 54.4 102.1 22.7 49.8 42.9 28.3 18.4 53.5 44.3 18.5 28.7 60.1 56.6 58.1 53.0 41.6 26.8 23.8 55.1 56.6 21.0 44.0 23.9 17.1 21.3 56.8 22.3 35.2 23.0 30.1 13.6 46.5 31.0 24.1 22.4 56.0 26.5 40.0 30.8 56.3 12.1 34.0 28.2 27.0 33.3 23.4 56.9 111.7 54.8 31.4 18.1 61.9 37.2 45.4 48.1 30.5 23.8 23.7 27.3 38.5 32.9 40.2 54.5 27.5 30.6 36.8 36.6 37.7 34.3 22.6 33.4 32.5 34.8 26.6 20.9 22.9 36.3 39.6 25.6 26.1 60.5 27.2 23.1 22.2 25.4 34.5 131.1 26.6 77.7 20.3 76.6 88.0 31.8 35.6 12.2 35.1 65.0 17.4 35.5 33.8 45.5 71.4 23.7 41.9 58.0 38.5 62.6 93.8 51.4 45.6 23.8 27.8 53.2 52.9 38.9 29.0 88.8 61.5 143.8 49.4 80.4 42.4 49.0 43.1 51.1 59.6 43.0 40.5 50.3 27.2 56.4 70.2 38.6 60.2 58.3 55.5 56.8 54.4 102.1 56.6 58.1 55.1 56.6 56.8 56.0 56.3 56.9 47.6 25.6 35.0 13.1 48.7 42.3 61.4 91.7 33.0 23.2 82.2 65.4 30.5 67.2 64.4 66.2 22.9 107.4 47.5 138.2 217.2 109.1 141.7 58.5 43.2 51.5 46.6 102.7 15.8 131.4 167.9 51.6 40.8 49.5 64.0 43.6 73.9 95.3 131.4 15.2 18.2 96.0 50.8 99.8 49.2 493.5 41.7 80.9 71.2 11.2 121.6 65.4 78.2 13.6 17.1 130.7 119.4 39.9 51.0 120.5 165.4 268.6 55.3 44.8 19.7 36.5 58.2 104.5 57.2 58.2 52.8 125.9 46.8 35.5 91.9 124.6 WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 324.4" "Cell type enhanced" "Detected in some" "Adipocytes: 66.4;Cytotrophoblasts: 16.5;Endothelial cells: 38.5;Hofbauer cells: 43.1;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1345.3;non-classical monocyte: 1608.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 908.5;SK-MEL-30: 1012.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 49000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 100.7 67.9 40.3 185.6 44.4 70.5 65.4 40.1 45.5 35.9 45.2 67.8 44.8 39.6 70.3 54.4 50.8 48.7 157.6 44.2 56.0 83.6 47.9 207.5 139.0 72.0 52.6 21.2 47.5 39.2 63.4 324.4 65.3 49.1 72.0 37.8 49.5 38.3 74.7 28.4 67.7 76.2 47.6 110.6 70.1 67.7 55.0 61.7 159.9 67.0 86.2 107.7 30.7 44.9 91.2 85.7 54.6 319.1 78.7 110.7 87.3 117.4 220.7 232.1 301.4 57.4 80.2 101.7 105.5 277.4 59.7 151.1 158.8 130.3 153.1 154.4 48.3 64.1 60.9 72.3 908.5 184.9 101.6 126.9 186.9 141.3 290.1 74.5 225.0 66.1 202.8 255.0 107.5 178.0 64.3 87.1 55.4 94.1 152.2 51.4 86.5 64.9 119.3 80.8 145.7 84.9 69.4 58.7 1012.4 70.5 153.6 234.7 153.1 25.7 58.9 269.2 61.3 446.4 277.1 191.9 295.0 144.2 205.5 96.5 471.7 610.4 41.5 1345.3 38.4 71.4 34.5 38.4 337.9 68.0 24.8 28.6 170.9 44.5 1608.2 54.7 44.8 672.7 40.3 44.4 40.1 45.5 44.2 56.0 72.0 52.6 65.3 47.6 55.0 44.9 66.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 16.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 11.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 0.0 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 79.9" "Group enriched" "Detected in many" 4 "dendritic cells: 101.0;NK-cells: 155.5;T-cells: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 41 "gdT-cell: 137.4;MAIT T-cell: 93.2;memory CD4 T-cell: 71.7;memory CD8 T-cell: 108.3;naive CD4 T-cell: 50.8;naive CD8 T-cell: 79.8;NK-cell: 112.2;T-reg: 80.1" "Group enriched" "Detected in many" 56 "NK-cells: 112.2;T-cells: 137.4" "Group enriched" "Detected in some" 11 "JURKAT: 121.0;MOLT-4: 183.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 14000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 3.3 1.3 0.5 28.0 0.6 24.8 1.9 0.5 0.9 1.7 0.7 4.0 5.8 1.4 0.5 2.3 2.2 5.4 1.4 0.5 0.7 2.8 3.9 8.7 57.0 0.8 1.3 0.8 1.0 0.4 1.1 0.9 0.7 2.5 1.5 0.0 2.3 0.8 2.0 2.4 18.5 0.5 0.6 35.5 6.7 2.7 1.2 79.9 3.5 2.8 17.7 4.9 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 121.0 0.0 0.7 0.0 0.0 183.4 0.5 0.1 0.0 0.0 7.2 0.1 9.1 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 14.1 0.1 0.0 0.0 0.3 0.3 0.5 137.4 0.4 93.2 0.2 71.7 108.3 0.3 1.6 50.8 79.8 2.2 112.2 1.0 0.9 80.1 64.2 0.5 0.6 0.5 0.9 0.5 0.7 0.8 1.3 0.7 0.6 1.2 0.6 0.8 9.6 13.6 0.3 3.9 1.5 0.0 0.0 0.0 0.0 0.8 0.5 3.0 0.0 0.0 0.0 0.0 0.1 101.0 0.2 1.9 0.2 1.0 1.6 0.5 0.8 0.0 8.8 0.2 0.0 0.0 1.8 4.6 0.4 2.5 0.1 2.5 0.7 2.2 0.0 0.2 0.0 0.0 2.8 2.2 0.7 0.0 3.4 1.8 2.8 5.0 0.0 155.5 0.0 0.1 0.0 0.0 0.0 28.0 0.1 0.0 0.5 0.0 0.0 0.0 14.3 0.6 1.3 2.1 0.2 1.4 0.0 105.6 0.1 0.1 0.2 ZBED3 MGC15435 ENSG00000132846 "Zinc finger BED-type containing 3" Q96IU2 5 77072072-77087285 "Predicted intracellular proteins, Predicted secreted proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.7;JURKAT: 31.0;MOLT-4: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055995 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA055995: AB_2683000" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.45e-2)" "unprognostic (6.96e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "unprognostic (3.63e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.08e-1)" "unprognostic (1.92e-1)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" 10.3 3.3 9.3 1.9 14.2 2.6 8.8 9.4 10.8 6.7 7.5 4.2 3.9 10.2 7.4 2.4 7.0 3.5 4.6 7.8 9.2 10.0 10.7 5.0 1.9 16.0 12.2 7.9 7.6 8.4 3.9 2.4 10.9 5.1 4.3 3.8 6.0 6.6 2.7 2.6 3.3 8.7 9.9 3.6 6.4 1.9 13.5 4.8 11.2 3.8 1.9 3.0 3.7 17.1 5.2 4.2 5.4 29.7 22.1 1.5 0.3 1.7 5.0 2.6 6.9 9.1 2.4 0.0 10.9 3.4 1.1 0.6 2.9 1.8 2.3 1.7 5.8 4.0 9.1 10.4 13.1 5.5 1.5 24.6 6.8 1.3 5.1 4.2 8.3 31.0 0.0 11.0 1.6 5.2 29.4 0.8 3.5 1.4 2.5 12.1 10.3 1.7 12.3 2.0 5.9 12.4 6.1 5.0 8.7 2.1 7.5 3.8 3.3 2.3 4.5 5.1 7.0 8.0 8.2 11.5 3.6 10.4 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 9.3 14.2 9.4 10.8 7.8 9.2 16.0 12.2 10.9 9.9 13.5 17.1 10.5 0.0 2.8 8.1 1.7 1.3 3.8 0.3 4.0 8.4 13.5 13.6 10.7 12.8 2.0 12.9 12.5 1.5 2.0 3.1 17.6 4.1 3.3 16.5 13.5 11.7 16.2 5.0 3.3 6.0 0.3 9.3 11.7 12.5 1.3 20.2 12.1 31.8 9.6 3.3 8.5 5.3 0.0 13.6 4.9 2.2 17.7 9.0 7.2 5.6 5.1 13.8 3.1 16.1 18.3 2.7 3.4 11.3 1.4 5.6 1.9 17.2 0.1 17.0 0.0 21.4 7.7 1.5 3.4 2.2 1.4 0.3 1.2 25.6 7.1 1.8 ZDHHC18 DKFZp667O2416 ENSG00000204160 "Zinc finger DHHC-type palmitoyltransferase 18" Q9NUE0 1 26826688-26857604 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 113.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.8" "Lineage enriched" "Detected in many" 18 "granulocytes: 48.8" "Cell line enhanced" "Detected in all" "HDLM-2: 132.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040234 Approved Approved Microtubules NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "HPA040234: AB_10805709" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.42e-7)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" "unprognostic (2.38e-2)" "unprognostic (2.13e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (1.36e-10)" "unprognostic (3.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 23.4 8.1 26.0 27.4 24.6 113.9 17.0 25.7 29.0 12.9 16.9 14.6 12.9 13.6 4.6 24.3 11.3 14.8 15.0 25.4 30.0 8.8 18.6 16.2 22.1 29.1 28.7 9.6 10.5 8.6 11.7 23.3 33.5 11.4 15.0 19.3 16.9 9.1 10.8 18.5 13.9 18.4 22.2 31.3 12.4 7.4 28.5 14.7 15.3 16.1 20.9 22.7 14.4 25.1 45.3 19.8 31.5 21.8 25.6 17.8 30.9 26.7 31.5 45.9 33.9 18.3 28.4 20.9 16.7 35.5 24.0 31.3 33.8 15.9 39.2 132.6 28.7 20.3 15.3 25.7 22.0 18.1 16.9 15.5 21.3 42.3 27.9 16.5 25.9 31.6 21.4 41.8 18.4 22.1 34.5 14.6 30.4 28.1 18.8 28.3 27.2 22.2 19.2 11.3 14.6 17.7 17.9 13.4 19.3 23.9 12.1 17.6 22.2 31.5 24.2 52.3 31.0 49.7 38.8 18.1 17.9 32.5 21.9 0.0 0.5 10.0 1.6 1.1 1.1 0.4 1.2 1.2 0.8 0.3 0.7 0.8 48.8 1.0 0.8 0.4 2.7 0.5 26.0 24.6 25.7 29.0 25.4 30.0 29.1 28.7 33.5 22.2 28.5 25.1 12.9 9.6 7.9 6.5 7.5 25.6 8.6 4.4 6.8 39.8 8.4 6.6 6.0 10.0 6.8 1.8 27.1 10.6 21.2 27.0 0.0 4.1 3.8 6.1 7.0 9.1 3.0 9.3 10.2 2.8 7.1 7.1 4.6 12.7 1.3 5.9 7.9 12.0 7.3 18.5 10.2 3.9 2.0 8.5 17.0 2.1 6.2 11.0 10.6 5.6 26.6 5.7 12.3 4.0 6.3 8.0 25.6 3.8 8.3 19.3 10.4 2.2 4.6 35.3 0.0 7.1 6.2 3.5 11.4 14.6 36.2 6.2 17.4 8.0 7.0 34.7 ZFHX4 "FLJ20980, ZFH4" ENSG00000091656 "Zinc finger homeobox 4" Q86UP3 8 76681239-76867281 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3" "Cell type enhanced" "Detected in many" "Astrocytes: 358.5;Bipolar cells: 87.2;Oligodendrocyte precursor cells: 234.2;Oligodendrocytes: 222.6;Skeletal myocytes: 120.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 16.8;TIME: 33.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023837 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli fibrillar center" "HPA023837: AB_1859013" "unprognostic (2.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.63e-3)" "unprognostic (6.14e-8)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.61e-2)" "unprognostic (2.61e-2)" "unprognostic (3.79e-2)" "unprognostic (9.15e-4)" "unprognostic (3.18e-2)" "unprognostic (1.17e-3)" "unprognostic (6.20e-7)" "unprognostic (3.50e-3)" "unprognostic (2.51e-1)" "unprognostic (4.50e-4)" "unprognostic (5.89e-4)" 3.0 3.6 7.5 0.5 12.0 0.0 2.1 0.9 9.3 3.2 0.0 3.2 0.0 0.8 3.2 0.3 0.6 0.9 0.4 6.0 18.9 0.3 2.8 0.1 0.3 11.3 23.3 1.9 0.2 0.2 2.8 0.1 17.7 1.0 0.5 2.2 0.6 5.5 2.8 0.4 0.3 1.1 7.0 0.1 0.8 6.7 15.3 0.6 0.3 3.1 0.0 2.7 2.6 15.0 0.0 2.2 3.8 0.0 7.2 8.7 0.0 3.3 4.6 3.8 3.9 0.0 0.0 0.0 5.8 5.7 1.7 0.4 7.8 1.0 7.6 0.0 10.3 0.1 0.0 0.0 1.9 0.0 0.5 16.8 0.4 9.5 3.0 6.5 0.7 0.0 0.1 0.3 7.0 0.0 0.0 0.0 0.6 0.4 7.1 0.0 6.8 0.0 5.8 0.0 0.0 6.5 0.0 0.8 0.0 0.0 0.9 0.0 33.4 3.7 5.6 10.6 7.4 10.9 1.2 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 12.0 0.9 9.3 6.0 18.9 11.3 23.3 17.7 7.0 15.3 15.0 5.4 0.0 1.5 358.5 0.3 0.5 0.1 1.0 2.2 87.2 2.4 2.2 4.0 42.9 0.3 5.5 2.1 0.1 0.2 0.0 0.0 0.1 70.0 0.0 1.1 2.0 0.0 0.0 13.7 0.0 0.0 37.5 0.0 0.0 0.0 0.1 1.1 30.5 0.4 5.0 12.6 0.2 0.0 0.6 1.8 24.3 13.7 0.7 0.0 29.0 0.0 15.0 0.0 234.2 222.6 0.0 0.0 21.4 0.1 0.3 0.0 0.3 0.3 5.8 0.0 120.6 8.1 12.4 2.3 1.2 1.1 0.0 0.6 10.0 0.0 0.9 ZP1 ENSG00000149506 "Zona pellucida glycoprotein 1" P60852 11 60867562-60875693 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Early spermatids: 32.3;Late spermatids: 87.6" "Cancer enhanced" "Detected in single" "prostate cancer: 0.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 32 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 32 "dendritic cells: 3.1" "Group enriched" "Detected in some" 40 "RPMI-8226: 12.4;SK-BR-3: 3.3" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (6.40e-3)" "unprognostic (2.18e-4)" "unprognostic (1.63e-1)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (7.02e-2)" "unprognostic (8.27e-2)" "unprognostic (9.95e-2)" "unprognostic (1.94e-2)" "unprognostic (8.15e-3)" "unprognostic (2.52e-1)" "unprognostic (9.25e-4)" "unprognostic (5.31e-13)" "unprognostic (4.13e-2)" "unprognostic (2.38e-1)" "unprognostic (6.27e-2)" "unprognostic (5.61e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 1.3 0.3 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.1 0.7 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 32.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 87.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.1 5.0 1.9 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.1