Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCD2 "ALDL1, ALDR, ALDRP" ENSG00000173208 "ATP binding cassette subfamily D member 2" Q9UBJ2 12 39550033-39619803 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.7;brain: 8.9" "Cell type enhanced" "Detected in some" "Astrocytes: 71.5;Bipolar cells: 57.2;Excitatory neurons: 33.2;Inhibitory neurons: 34.2" "Cancer enriched" "Detected in single" 7 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in single" 4 "T-cells: 4.2" "Group enriched" "Detected in some" 6 "ASC diff: 11.6;HDLM-2: 16.9;Karpas-707: 29.0;SH-SY5Y: 17.3;U-266/70: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.26e-3)" "unprognostic (4.06e-4)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (2.06e-1)" "unprognostic (7.31e-5)" "unprognostic (3.42e-2)" "unprognostic (2.90e-2)" "unprognostic (8.06e-3)" "unprognostic (3.43e-2)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-4)" "unprognostic (5.04e-2)" "unprognostic (8.04e-2)" "unprognostic (1.13e-1)" "unprognostic (6.74e-2)" 15.7 1.7 1.5 1.7 2.2 0.2 2.8 8.9 5.2 5.3 0.0 0.7 0.5 2.7 0.2 0.4 2.7 0.5 4.2 2.1 2.1 0.5 0.1 0.5 2.8 2.2 3.3 0.1 0.1 0.0 0.5 0.0 2.4 0.4 0.7 5.9 2.6 0.6 0.1 0.1 0.7 2.6 1.3 1.6 0.7 0.2 3.6 1.4 0.2 0.3 1.6 0.9 0.6 1.4 0.0 0.0 0.1 0.0 11.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 16.9 0.0 0.1 0.0 0.0 0.6 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 9.8 1.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 1.2 0.5 2.8 3.7 0.1 0.3 3.2 4.2 0.1 0.9 0.0 0.6 3.6 1.2 1.5 2.2 8.9 5.2 2.1 2.1 2.2 3.3 2.4 1.3 3.6 1.4 0.4 0.0 0.0 71.5 2.6 0.0 0.0 0.0 0.0 57.2 0.3 0.3 10.9 0.0 0.0 0.0 6.2 0.0 3.8 0.1 0.0 0.0 0.3 0.2 0.5 0.2 0.0 0.0 33.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.1 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.5 1.1 2.2 0.0 13.0 1.3 0.0 0.0 0.7 5.9 0.0 0.0 0.9 2.4 2.3 0.0 0.4 2.5 0.2 0.1 0.0 0.0 0.0 7.8 0.6 0.1 0.0 ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6393767 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 128.7" "Cell type enhanced" "Detected in many" "granulocytes: 137.2;Late spermatids: 160.8;Proximal enterocytes: 179.4;Proximal tubular cells: 253.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "NK-cell: 40.2;plasmacytoid DC: 35.7" "Group enriched" "Detected in many" 5 "dendritic cells: 35.7;NK-cells: 40.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol No No 26000 "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" 11.3 20.4 72.8 18.7 72.8 14.7 9.9 56.2 108.2 17.8 16.7 32.7 55.1 18.2 5.5 35.0 11.0 8.2 17.3 75.1 107.2 47.8 22.0 17.9 22.4 96.1 88.5 11.2 9.0 3.8 65.1 10.4 128.7 12.9 21.4 24.5 11.9 6.9 5.2 27.1 56.1 23.5 46.9 20.7 19.2 38.1 83.9 28.3 6.1 4.7 19.4 18.0 23.5 68.4 117.6 100.0 96.6 104.6 21.7 35.6 36.4 98.6 50.6 142.7 85.1 347.7 37.0 142.4 70.6 80.4 110.3 113.0 156.9 263.2 53.2 126.0 136.7 75.2 74.4 124.9 88.7 88.8 59.9 32.1 49.6 118.2 139.2 38.1 81.2 174.8 62.3 29.8 76.8 136.6 187.0 94.0 48.5 116.9 228.2 219.9 110.6 95.6 80.9 44.2 52.6 149.1 88.9 134.5 317.9 47.3 47.9 41.2 133.0 129.1 75.4 129.6 158.9 24.9 110.6 202.1 81.8 153.7 80.3 0.0 0.3 0.2 7.3 1.2 1.8 2.1 5.8 6.2 5.4 0.7 2.0 3.9 0.7 40.2 0.9 35.7 8.2 5.3 72.8 72.8 56.2 108.2 75.1 107.2 96.1 88.5 128.7 46.9 83.9 68.4 3.4 6.4 16.4 9.4 4.9 31.7 16.5 24.2 12.5 46.8 4.1 7.5 9.8 8.6 14.9 9.2 10.4 20.9 14.4 45.4 15.6 22.7 95.5 4.0 6.1 19.1 4.8 26.5 38.6 7.2 29.7 11.5 19.9 7.6 137.2 13.2 8.6 16.8 30.1 47.1 38.9 110.2 36.7 4.8 85.9 160.8 3.7 13.4 39.2 5.6 15.7 12.8 8.2 22.6 21.0 23.2 41.8 7.2 9.3 9.5 179.4 253.7 7.1 24.4 0.0 6.7 17.6 37.8 28.0 26.2 29.5 17.2 21.7 13.7 51.3 19.6 ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904871-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.9;lymphoid tissue: 10.9" "Group enriched" "Detected in some" 6 "Excitatory neurons: 13.4;granulocytes: 43.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SCLC-21H: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065887 Supported Supported "Secreted in other tissues" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA065887: " "unprognostic (2.68e-1)" "unprognostic (1.83e-2)" "unprognostic (7.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.87e-4)" "unprognostic (9.58e-3)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (6.86e-2)" "unprognostic (4.16e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.91e-6)" "unprognostic (2.24e-3)" "unprognostic (9.22e-2)" "unprognostic (1.74e-1)" "unprognostic (5.74e-4)" 1.8 0.2 1.9 10.9 2.6 0.0 1.3 0.3 2.9 2.1 0.0 1.8 0.1 3.0 0.0 1.3 0.4 7.1 0.5 2.7 21.7 0.5 0.2 1.6 1.0 31.9 6.8 0.1 4.8 0.2 3.5 0.1 13.7 1.4 1.1 0.3 1.9 0.5 0.2 0.7 1.3 1.0 5.4 0.1 1.5 2.5 17.7 0.4 0.2 0.0 1.0 2.3 1.3 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.6 0.3 2.9 2.7 21.7 31.9 6.8 13.7 5.4 17.7 2.0 0.2 3.2 0.6 0.3 0.0 0.6 0.1 0.1 0.0 0.5 0.1 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.0 13.4 0.0 0.0 2.4 0.0 0.0 43.1 0.0 0.4 0.0 0.1 0.0 0.5 0.0 4.1 0.0 0.9 1.5 0.3 0.2 0.0 1.9 0.0 0.2 0.0 0.5 1.1 2.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 2.6 0.0 0.0 0.4 0.0 2.0 0.0 0.0 0.2 ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1227.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Endometrial stromal cells: 5.4;Fibroblasts: 5.3;Gastric mucus-secreting cells: 9.2;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.0;BEWO: 7.3;HeLa: 5.9;NTERA-2: 6.4;RPMI-8226: 4.5;SH-SY5Y: 6.6;U-2197: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" 3.9 0.3 0.1 0.9 0.1 0.0 2.0 0.0 1.1 1.0 0.0 0.5 0.5 1.0 1227.7 0.5 16.5 1.6 1.3 0.8 0.7 0.4 0.7 1.3 5.0 0.4 1.5 0.2 1.2 163.4 1.1 0.5 0.6 2.1 0.4 0.9 8.5 3.6 0.2 0.4 1.1 0.4 0.1 2.4 9.0 1.9 0.3 6.6 1.6 1.1 3.7 0.8 1.0 0.2 0.2 6.0 0.0 0.0 0.1 0.9 7.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.4 0.0 5.9 0.2 0.8 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 2.2 6.4 0.0 2.0 0.0 0.0 4.5 0.0 1.2 2.2 6.6 1.5 0.1 0.0 1.1 0.1 0.1 0.1 0.2 0.4 14.6 2.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.8 0.7 0.4 1.5 0.6 0.1 0.3 0.2 0.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.0 0.6 1.2 1.1 1.0 7.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.1 1.1 5.4 0.6 0.0 0.0 4.4 0.2 0.3 5.3 9.2 3.2 0.0 0.2 1.4 0.4 0.0 3.3 5.0 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.0 4.7 0.0 4.8 0.0 10.1 7.0 3.1 0.0 1.5 0.0 3.4 0.0 0.1 2.2 0.7 0.0 1.6 0.6 0.1 1.4 0.1 0.0 0.0 0.3 0.3 0.0 0.3 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.5;Horizontal cells: 274.2;Muller glia cells: 127.1;Proximal enterocytes: 120.0;Rod photoreceptor cells: 348.5" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 250.9;U-266/70: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 87.0 24.3 953.6 12.7 909.7 23.6 42.5 1238.3 1162.3 39.3 589.6 18.5 18.7 17.9 10.9 40.8 14.3 10.9 285.5 955.7 958.0 16.8 98.3 13.7 19.3 1297.5 962.6 39.1 4.9 12.1 30.6 4.1 1384.6 18.9 14.7 1183.1 19.9 15.8 4.8 74.5 43.9 12.4 926.9 24.4 23.3 14.2 1090.2 9.6 7.4 8.1 30.5 19.0 47.0 886.1 29.9 2.1 13.7 55.7 29.9 32.9 2.9 16.7 37.7 12.9 76.0 17.9 3.0 14.9 17.3 15.5 3.3 36.9 10.3 102.3 23.4 12.4 8.9 28.3 11.6 30.4 25.8 10.0 29.2 27.8 13.9 1.5 24.0 1.7 5.3 29.7 19.3 71.9 10.7 15.1 11.9 32.0 20.8 6.7 15.3 9.5 1.6 250.9 1.9 4.3 36.2 61.9 9.1 67.3 0.5 20.8 36.6 21.2 3.5 1.2 5.3 2.1 2.4 161.0 51.4 10.9 105.2 28.0 1.9 0.5 7.4 3.0 21.6 8.7 30.6 24.0 29.5 17.8 9.4 25.1 37.7 28.4 18.0 29.4 5.3 4.6 40.9 19.0 953.6 909.7 1238.3 1162.3 955.7 958.0 1297.5 962.6 1384.6 926.9 1090.2 886.1 4.2 0.0 15.8 97.6 9.8 7.5 20.3 80.5 8.6 112.5 9.0 11.0 22.1 11.5 29.3 7.3 106.3 1.1 9.5 31.7 3.9 21.9 0.9 1.0 3.0 11.3 21.6 3.2 19.2 10.2 6.5 5.8 6.6 1.2 13.3 4.9 14.3 93.1 5.4 274.2 41.3 12.9 28.5 4.4 5.3 1.3 9.3 3.1 24.9 21.5 34.1 127.1 12.3 26.7 16.8 12.4 12.4 10.1 2.6 6.1 120.0 2.1 11.8 348.5 13.1 6.4 10.1 0.3 3.2 7.9 10.9 1.5 17.0 11.7 5.1 7.8 APC2 APCL ENSG00000115266 "APC regulator of WNT signaling pathway 2" O95996 19 1446302-1473244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 64.5" "Cell type enhanced" "Detected in some" "Astrocytes: 142.4;Bipolar cells: 50.4;Excitatory neurons: 26.8;Horizontal cells: 45.4;Inhibitory neurons: 27.5;Muller glia cells: 29.4;Oligodendrocyte precursor cells: 28.1" "Cancer enriched" "Detected in some" 27 "glioma: 17.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.8;SCLC-21H: 9.3;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078002 Supported "Cytokinetic bridge,Midbody,Cytosol" Yes No "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Cytokinetic bridge, Midbody" Cytosol "HPA078002: AB_2686874" "unprognostic (1.78e-3)" "unprognostic (1.65e-1)" "unprognostic (2.88e-5)" "unprognostic (3.64e-2)" "unprognostic (3.59e-1)" "unprognostic (1.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (1.38e-2)" "unprognostic (1.30e-2)" "unprognostic (3.45e-2)" "unprognostic (9.49e-3)" "unprognostic (7.39e-2)" "unprognostic (3.70e-2)" "unprognostic (4.99e-2)" "unprognostic (1.98e-3)" 0.1 2.4 41.5 0.0 27.3 0.0 0.0 41.4 42.4 0.1 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.1 0.3 37.1 20.8 0.0 0.0 0.0 0.0 64.5 42.3 0.0 0.3 0.0 6.2 0.0 54.9 0.1 0.0 2.7 0.2 0.0 0.2 0.1 0.4 0.1 38.3 0.0 0.3 1.0 54.6 0.0 0.1 0.0 0.0 0.1 0.2 49.0 0.2 0.6 7.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.0 1.0 0.1 0.0 0.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.6 0.0 0.0 9.3 31.7 1.1 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.6 0.1 0.1 1.7 0.5 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 27.3 41.4 42.4 37.1 20.8 64.5 42.3 54.9 38.3 54.6 49.0 0.3 0.0 0.0 142.4 0.3 0.0 0.2 0.2 1.2 50.4 0.4 0.4 3.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.5 0.5 0.5 0.0 0.0 26.8 0.0 0.1 0.3 0.0 0.6 0.0 0.2 0.0 0.0 0.1 45.4 27.5 0.0 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.7 0.0 29.4 2.1 28.1 17.8 0.0 0.0 0.7 0.0 0.1 0.2 0.2 0.0 11.1 0.0 0.6 0.4 0.4 0.7 2.4 0.0 0.0 0.3 0.2 0.1 0.2 ASPHD1 ENSG00000174939 "Aspartate beta-hydroxylase domain containing 1" Q5U4P2 16 29900375-29919864 "Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 138.6;choroid plexus: 79.3;pituitary gland: 36.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 27.1;Enteroendocrine cells: 29.4;Excitatory neurons: 25.1;Gastric mucus-secreting cells: 32.1;Inhibitory neurons: 22.6;Oligodendrocytes: 29.3;Pancreatic endocrine cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 61.7;Hep G2: 79.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045175 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "HPA045175: AB_10959899" "unprognostic (1.58e-1)" "unprognostic (5.50e-2)" "unprognostic (4.74e-3)" "unprognostic (2.20e-3)" "unprognostic (1.34e-3)" "unprognostic (6.96e-2)" "unprognostic (5.75e-2)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (8.37e-2)" "prognostic favorable (7.38e-4)" "unprognostic (5.55e-2)" "unprognostic (6.17e-2)" "unprognostic (1.97e-2)" "unprognostic (1.90e-1)" "unprognostic (2.97e-1)" "unprognostic (9.03e-2)" 5.5 5.1 113.3 0.7 119.8 0.1 0.8 106.3 138.6 1.3 79.3 1.3 2.5 3.0 0.1 0.4 1.3 14.8 0.8 108.6 101.7 4.4 0.7 1.1 0.2 113.3 113.9 1.3 9.1 0.8 36.4 0.2 111.9 1.5 0.9 2.3 4.9 0.5 0.2 0.3 1.7 1.4 110.4 0.3 20.9 5.9 110.1 0.0 0.1 0.2 0.2 0.8 0.4 117.6 3.3 14.5 0.0 16.7 0.0 2.4 0.9 15.8 5.1 18.0 12.9 35.1 61.7 6.2 39.4 10.5 13.0 2.4 2.0 4.2 3.4 1.0 2.4 3.1 50.9 79.1 29.1 0.7 40.5 18.3 3.9 26.7 2.7 19.4 0.7 11.3 0.2 13.1 4.3 32.1 0.9 0.6 23.0 13.7 13.8 1.2 0.0 2.5 18.4 0.4 47.3 19.3 0.2 26.1 5.2 0.3 10.0 11.9 1.2 7.5 13.2 0.4 4.5 1.1 0.4 0.6 23.7 41.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.3 119.8 106.3 138.6 108.6 101.7 113.3 113.9 111.9 110.4 110.1 117.6 0.7 0.0 5.1 4.9 0.1 0.6 4.8 2.5 0.0 19.2 4.3 3.9 0.3 27.1 0.5 1.8 4.2 0.0 0.0 2.6 1.9 17.3 1.9 0.7 9.4 0.9 29.4 0.0 25.1 20.2 0.4 7.8 32.1 1.4 1.3 0.5 0.0 0.2 4.0 6.7 22.6 4.2 6.1 0.0 0.3 1.2 0.3 0.9 1.8 5.6 0.0 1.7 0.0 9.0 29.3 29.3 0.3 0.7 0.1 8.1 1.7 3.7 0.3 10.2 0.0 0.2 2.5 1.2 1.0 0.0 0.6 0.3 0.2 4.8 4.2 2.8 BEX1 ENSG00000133169 "Brain expressed X-linked 1" Q9HBH7 X 103062651-103064171 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 439.4;pituitary gland: 399.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 354.2;Granulosa cells: 260.7;Horizontal cells: 363.4;Muller glia cells: 716.1;Rod photoreceptor cells: 142.2" "Cancer enhanced" "Detected in many" "glioma: 111.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 607.0;HBF TERT88: 680.4;HL-60: 1562.2;hTERT-RPE1: 1044.5;SCLC-21H: 465.3;U-937: 484.1" "HPA045384, HPA078630" Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 32: U-937 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA045384: AB_2679305, HPA078630: " "prognostic favorable (6.43e-4)" "unprognostic (1.51e-1)" "unprognostic (8.92e-2)" "unprognostic (2.94e-2)" "unprognostic (1.66e-1)" "unprognostic (7.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-2)" "unprognostic (5.28e-3)" "unprognostic (2.09e-1)" "prognostic favorable (8.16e-8)" "unprognostic (1.14e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (6.88e-4)" "unprognostic (7.34e-2)" 1.5 83.8 253.7 3.8 260.1 42.7 2.5 201.9 317.4 5.5 142.9 10.5 5.0 15.6 55.5 0.8 21.4 1.3 16.7 274.9 439.4 10.7 4.2 2.8 1.2 222.6 248.2 20.2 71.6 112.0 399.2 0.4 261.1 6.7 4.3 173.0 2.3 3.6 0.6 1.0 6.3 4.8 203.1 2.5 8.6 92.9 265.5 3.5 26.0 0.8 0.4 0.8 2.9 223.9 0.7 0.0 37.6 0.1 0.0 0.1 1.1 21.6 0.0 412.1 607.0 0.0 0.1 0.1 0.8 158.1 130.0 0.4 0.0 0.5 680.4 0.2 1.2 129.2 0.0 85.2 6.9 1562.2 2.6 9.2 0.0 89.3 0.1 1044.5 0.1 120.8 0.2 0.2 84.6 0.0 294.7 0.2 337.9 97.8 62.0 0.2 0.7 7.6 0.0 0.3 465.3 266.6 0.5 0.6 1.9 5.9 0.3 432.4 0.0 0.1 140.2 1.1 16.7 71.9 2.9 0.7 54.4 484.1 27.2 0.4 0.2 3.4 0.3 0.0 0.3 0.5 0.9 0.5 0.0 1.0 1.4 0.6 0.5 0.9 0.2 0.1 0.4 0.7 253.7 260.1 201.9 317.4 274.9 439.4 222.6 248.2 261.1 203.1 265.5 223.9 1.1 0.0 0.5 16.3 1.2 8.7 11.1 0.0 1.2 354.2 7.2 32.5 9.6 31.5 0.7 5.5 39.6 0.2 0.2 0.4 72.4 6.1 12.1 1.4 0.6 5.3 79.6 0.8 64.6 13.8 0.2 3.9 8.2 2.8 0.0 260.7 30.4 1.2 1.4 363.4 56.1 6.9 10.2 4.0 1.2 31.8 8.1 2.2 7.2 12.2 1.5 716.1 0.0 32.6 20.9 6.3 3.3 2.6 0.0 7.5 0.8 19.5 0.0 142.2 0.0 15.9 14.4 38.5 13.8 0.0 6.5 0.5 2.0 0.2 3.5 1.7 BRINP2 "DBCCR1L2, FAM5B" ENSG00000198797 "BMP/retinoic acid inducible neural specific 2" Q9C0B6 1 177170958-177282422 "Predicted secreted proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.6;brain: 19.9" "Group enriched" "Detected in some" 4 "Astrocytes: 121.1;Excitatory neurons: 116.8;Inhibitory neurons: 148.3;Oligodendrocyte precursor cells: 96.5" "Cancer enriched" "Detected in some" 5 "glioma: 11.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.7;PC-3: 1.3;REH: 2.1;SCLC-21H: 5.6;SH-SY5Y: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050681 Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA050681: " "unprognostic (7.78e-2)" "unprognostic (4.49e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.43e-2)" "unprognostic (1.77e-1)" "unprognostic (5.77e-2)" "unprognostic (1.23e-2)" "unprognostic (1.95e-2)" "unprognostic (2.20e-4)" "unprognostic (8.95e-2)" "unprognostic (1.78e-2)" "unprognostic (2.60e-3)" "unprognostic (1.17e-1)" "unprognostic (2.60e-2)" "unprognostic (4.82e-3)" 0.6 9.6 17.2 0.0 16.5 0.0 0.9 1.3 19.9 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.2 17.9 10.7 0.0 0.1 0.0 0.0 4.5 9.6 0.0 0.0 0.0 4.2 0.5 4.9 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 2.1 16.2 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 2.1 0.0 0.0 0.0 0.0 5.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 16.5 1.3 19.9 17.9 10.7 4.5 9.6 4.9 4.9 16.2 13.4 0.0 0.0 0.0 121.1 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.4 0.2 0.3 0.0 0.0 0.0 116.8 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.0 0.1 15.2 148.3 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 25.3 0.0 0.5 0.0 96.5 15.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 1.3 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 CALCB "CALC2, CGRP-II, FLJ30166" ENSG00000175868 "Calcitonin related polypeptide beta" P10092 11 14904997-15082342 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 18.9;thyroid gland: 20.7" "Group enriched" "Detected in some" 4 "Melanocytes: 5.4;Spermatogonia: 5.1" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;endometrial cancer: 2.4;thyroid cancer: 0.9" "Group enriched" "Detected in many" 4 "hypothalamus: 6.8;medulla oblongata: 8.9;midbrain: 11.6;pons: 18.9;white matter: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 5.8;Karpas-707: 10.4;SH-SY5Y: 3.5;U-266/70: 16.0" "Region enriched" "Detected in some" 7 "pons and medulla: 9.6" "Group enriched" "Detected in many" 5 "amygdala: 30.4;basal ganglia: 74.3;hypothalamus: 50.1;midbrain: 33.9;pons: 41.7" HPA059886 Supported "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA059886: " "unprognostic (7.84e-2)" "unprognostic (4.07e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (3.42e-5)" "unprognostic (2.02e-1)" "unprognostic (8.40e-2)" "unprognostic (1.75e-1)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "unprognostic (3.32e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-1)" "unprognostic (1.02e-2)" "unprognostic (2.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" 0.3 0.0 0.1 0.3 0.2 0.0 0.2 0.5 0.6 0.2 0.1 1.4 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.3 6.8 1.0 0.8 0.1 0.1 8.9 11.6 0.1 1.5 0.3 2.2 0.1 18.9 0.1 0.2 0.1 0.3 0.0 0.8 0.1 0.4 0.1 2.3 0.1 0.1 0.3 1.0 0.0 20.7 0.1 0.1 0.0 0.1 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.2 5.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 1.9 0.0 0.4 0.1 0.0 10.4 0.0 0.0 0.0 0.6 2.9 0.1 0.1 0.4 0.0 0.2 0.0 0.0 1.1 3.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 16.0 0.6 0.4 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.6 0.3 6.8 8.9 11.6 18.9 2.3 1.0 4.7 0.0 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.0 0.0 0.6 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.1 0.4 0.0 0.0 0.4 0.2 0.9 0.5 0.2 0.5 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.3 0.0 0.0 5.4 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.9 5.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 CCDC184 "C12orf68, LOC387856" ENSG00000177875 "Coiled-coil domain containing 184" Q52MB2 12 48183644-48185926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell type enhanced" "Detected in many" "Early spermatids: 62.5;Late spermatids: 15.1;Sertoli cells: 46.0" "Cancer enhanced" "Detected in many" "glioma: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;AF22: 6.3;hTERT-RPE1: 2.4;SH-SY5Y: 4.3;U-2 OS: 2.5;U-87 MG: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039947, HPA041715" Uncertain Approved Mitochondria,Cytosol No No "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Mitochondria, Cytosol" "HPA039947: AB_2676764, HPA041715: AB_2677634" "unprognostic (2.02e-1)" "unprognostic (1.16e-2)" "unprognostic (6.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.61e-2)" "unprognostic (4.59e-1)" "unprognostic (1.33e-2)" "unprognostic (6.65e-2)" "unprognostic (9.79e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-2)" "unprognostic (1.07e-1)" "unprognostic (5.87e-4)" "unprognostic (1.08e-2)" "unprognostic (2.39e-2)" "unprognostic (2.55e-1)" "unprognostic (2.36e-2)" 1.1 5.3 12.3 0.9 12.0 0.1 1.0 11.2 21.4 3.5 1.1 1.8 0.2 5.4 0.3 0.9 1.0 1.3 2.3 10.8 25.7 0.7 0.3 0.8 0.2 18.3 12.5 7.5 0.6 5.8 11.6 2.3 24.5 1.4 0.4 5.0 0.4 0.8 0.9 0.4 0.9 1.4 7.5 0.9 1.0 6.2 11.9 0.0 0.9 0.4 0.0 2.0 1.5 10.8 0.0 2.7 6.3 0.2 0.5 0.5 0.0 0.2 1.2 0.3 0.5 0.3 0.1 0.0 0.1 0.2 1.6 0.1 0.6 0.1 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 4.3 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.7 2.5 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 12.0 11.2 21.4 10.8 25.7 18.3 12.5 24.5 7.5 11.9 10.8 1.2 0.0 0.0 2.6 1.1 0.0 0.1 0.0 6.2 2.3 0.3 1.9 0.6 0.0 0.6 0.0 0.0 0.7 2.0 0.1 0.0 0.3 62.5 0.4 9.4 3.1 5.3 0.0 5.6 0.0 0.6 11.2 1.1 0.2 0.0 4.2 6.8 0.0 0.9 5.0 12.7 0.0 0.0 0.3 0.0 15.1 0.3 0.5 0.0 1.0 0.0 3.0 0.0 1.5 1.1 0.1 0.0 2.2 0.2 0.1 0.0 0.0 5.1 7.0 46.0 8.6 7.6 12.7 1.8 2.2 0.0 1.5 3.2 1.8 0.0 0.0 CDH10 ENSG00000040731 "Cadherin 10" Q9Y6N8 5 24487100-24644978 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 13.0;prostate: 4.4" "Group enriched" "Detected in some" 20 "Astrocytes: 169.4;Excitatory neurons: 423.4;Inhibitory neurons: 216.9;Oligodendrocyte precursor cells: 488.6" "Cancer enriched" "Detected in some" 4 "glioma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 7.1;HAP1: 4.6;hTERT-RPE1: 4.2;SuSa: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010651, HPA012085" Approved Approved "Nucleoplasm,Cell Junctions" NA NA 270000 "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" Nucleoplasm "HPA010651: AB_1078370, HPA012085: " "unprognostic (4.31e-3)" "unprognostic (2.77e-1)" "unprognostic (1.88e-1)" "unprognostic (3.66e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-3)" "unprognostic (6.27e-2)" "unprognostic (1.59e-7)" "unprognostic (1.65e-2)" "unprognostic (1.41e-1)" "unprognostic (8.74e-3)" 0.0 0.7 5.6 0.0 8.4 0.0 0.1 13.0 8.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 9.0 0.9 0.0 0.0 0.1 0.0 0.3 1.7 0.0 0.1 0.0 0.4 0.0 2.2 4.4 0.2 1.0 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.3 1.1 0.0 0.0 1.1 0.0 0.0 0.1 4.6 0.0 0.0 7.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 11.7 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.4 13.0 8.7 9.0 0.9 0.3 1.7 2.2 1.2 1.1 4.6 0.0 0.0 0.0 169.4 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.4 0.1 0.0 0.0 423.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 216.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.9 0.0 0.6 0.0 488.6 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 CDK5R1 "Nck5a, p35, p35nck5a" ENSG00000176749 "Cyclin dependent kinase 5 regulatory subunit 1" Q15078 17 32486993-32491253 "Predicted intracellular proteins" "Biological rhythms" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 63.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.9;Early spermatids: 21.2;Excitatory neurons: 36.6;Inhibitory neurons: 31.6;Late spermatids: 18.9" "Cancer enhanced" "Detected in many" "melanoma: 14.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "SCLC-21H: 58.1;SH-SY5Y: 15.6;SK-MEL-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000252 Approved Nucleoplasm,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA000252: AB_2665953" "unprognostic (1.08e-1)" "unprognostic (9.13e-2)" "unprognostic (1.79e-2)" "unprognostic (3.65e-1)" "unprognostic (1.97e-1)" "unprognostic (8.09e-2)" "unprognostic (2.74e-5)" "unprognostic (1.81e-2)" "unprognostic (3.32e-1)" "unprognostic (2.18e-1)" "unprognostic (5.90e-2)" "unprognostic (5.60e-1)" "unprognostic (6.98e-2)" "unprognostic (1.60e-1)" "unprognostic (7.92e-2)" "unprognostic (8.81e-2)" "unprognostic (1.03e-1)" 0.8 2.8 37.8 7.1 50.8 5.4 1.2 11.0 63.5 1.5 0.0 0.9 1.4 0.9 0.2 7.5 0.7 0.9 1.1 53.4 21.1 0.8 1.0 0.8 13.9 3.2 10.5 2.6 1.4 0.7 6.9 0.6 4.5 0.6 0.8 10.4 1.1 0.5 2.3 1.9 3.6 0.6 3.5 12.1 1.6 7.2 21.7 4.2 0.5 0.8 14.1 0.8 3.1 34.2 3.9 2.2 9.8 3.1 1.1 1.8 1.1 2.4 1.4 2.9 3.7 5.7 0.9 1.9 2.2 2.0 2.4 1.8 3.8 2.4 3.8 0.7 7.3 0.7 1.1 2.3 0.5 1.3 1.9 1.1 5.8 2.9 2.4 1.1 2.1 6.9 3.9 2.2 6.2 1.6 3.4 1.5 6.2 1.4 2.1 2.9 5.9 7.1 1.4 1.7 58.1 15.6 2.3 1.3 43.8 1.4 2.5 4.4 2.2 4.0 5.9 1.6 6.3 1.1 1.5 1.9 3.4 5.6 9.7 0.0 0.3 0.4 0.8 0.3 0.6 0.2 1.1 0.4 0.0 0.1 1.5 0.9 1.2 0.2 0.1 0.6 0.1 0.6 37.8 50.8 11.0 63.5 53.4 21.1 3.2 10.5 4.5 3.5 21.7 34.2 1.7 0.0 1.5 6.5 13.1 1.5 0.5 1.0 7.4 15.9 3.7 2.3 3.6 0.0 0.8 0.0 45.9 0.6 10.1 0.3 0.0 0.2 21.2 1.1 1.3 1.2 0.0 0.0 36.6 0.6 0.3 1.2 0.5 1.5 0.0 1.6 0.7 0.7 0.9 1.7 31.6 1.4 2.0 3.5 0.5 18.9 0.0 1.3 3.6 2.8 2.0 18.4 10.3 9.5 11.9 1.2 1.2 0.7 0.9 1.2 0.4 1.5 1.0 6.3 0.0 2.9 3.1 6.7 4.3 8.8 1.3 1.1 7.1 1.9 1.1 0.5 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 59.0;pituitary gland: 57.3;testis: 31.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 84.3;Early spermatids: 217.8;Excitatory neurons: 80.4;Horizontal cells: 225.4;Inhibitory neurons: 56.2;Late spermatids: 113.2;Rod photoreceptor cells: 49.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 12.9;U-2 OS: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 0.2 4.1 31.8 0.2 40.1 0.0 0.1 0.0 59.0 0.4 0.0 1.1 0.2 0.4 0.0 0.3 0.4 0.1 0.4 34.3 13.6 2.4 0.1 0.3 0.0 3.9 11.1 0.5 0.4 0.9 57.3 0.0 4.4 0.9 0.2 7.9 0.2 2.2 0.2 0.3 0.4 0.1 0.9 0.1 1.0 31.8 10.2 0.3 0.1 0.0 0.0 0.7 0.6 31.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.1 0.2 1.1 0.0 0.0 0.0 0.0 12.9 0.2 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.8 40.1 0.0 59.0 34.3 13.6 3.9 11.1 4.4 0.9 10.2 31.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 0.0 84.3 0.1 0.3 2.1 0.0 0.0 3.7 12.5 0.0 0.1 0.2 0.0 0.0 217.8 0.0 0.2 0.6 0.0 0.0 80.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 225.4 56.2 0.0 0.0 0.0 0.3 113.2 0.9 0.1 0.0 2.8 0.0 2.0 0.0 4.5 3.7 0.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 49.9 0.0 0.2 0.5 4.5 17.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 CHRNA7 ENSG00000175344 "Cholinergic receptor nicotinic alpha 7 subunit" P36544 15 31923438-32173018 "FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.8;intestine: 9.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 9.0;Gastric mucus-secreting cells: 26.0;Horizontal cells: 16.8;Inhibitory neurons: 30.7;Proximal enterocytes: 14.4" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.3;RT4: 12.9;SH-SY5Y: 8.3;SK-BR-3: 13.3;U-2 OS: 10.8" "HPA029422, CAB033624" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB033624: AB_784835, HPA029422: AB_10600863" "unprognostic (3.43e-2)" "unprognostic (8.44e-2)" "unprognostic (2.02e-1)" "unprognostic (4.61e-4)" "unprognostic (6.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.14e-2)" "unprognostic (5.08e-2)" "unprognostic (1.63e-1)" "unprognostic (4.31e-2)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (2.40e-2)" "unprognostic (4.36e-3)" "unprognostic (5.44e-2)" "unprognostic (7.41e-3)" "unprognostic (2.43e-1)" 0.3 7.8 1.2 0.4 1.1 0.9 1.0 1.8 1.8 0.4 2.1 1.5 4.4 0.5 0.3 0.3 0.4 0.9 0.5 1.0 4.5 0.4 0.1 0.5 0.7 4.5 3.9 1.6 2.4 6.4 1.0 0.0 7.0 1.2 2.3 2.5 0.5 0.7 0.5 0.3 9.7 0.4 1.5 1.2 6.6 2.5 3.3 0.4 2.2 0.8 0.7 1.5 0.7 1.1 0.0 1.3 2.7 6.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 3.1 0.0 0.0 0.0 1.7 0.6 0.0 2.2 0.0 0.4 1.0 0.0 0.0 0.2 0.0 0.1 0.4 2.5 0.0 0.2 0.3 0.2 0.0 0.2 1.5 3.7 0.0 0.0 4.2 0.3 0.5 12.9 0.5 8.3 0.2 13.3 0.0 0.7 0.0 0.5 1.2 0.0 10.8 0.3 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.2 1.1 1.8 1.8 1.0 4.5 4.5 3.9 7.0 1.5 3.3 1.1 0.5 0.0 0.0 1.0 0.0 0.3 3.0 0.0 7.4 1.8 1.1 1.3 1.1 2.8 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.3 0.1 0.2 0.3 1.5 3.0 0.0 9.0 2.5 0.0 0.4 26.0 0.6 1.3 4.6 0.7 0.0 0.1 16.8 30.7 8.9 0.0 0.0 0.9 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.5 1.1 1.6 2.9 0.0 0.2 0.7 14.4 0.2 0.0 0.0 0.0 0.4 0.3 0.2 5.9 3.2 0.0 0.0 0.1 0.2 2.0 1.2 CLVS1 "C6orf212L, CRALBPL, MGC34646, RLBP1L1" ENSG00000177182 "Clavesin 1" Q8IUQ0 8 61057158-61501645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.9;retina: 5.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 113.1;Inhibitory neurons: 158.1;Oligodendrocyte precursor cells: 90.0;Oligodendrocytes: 37.3" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "Daudi: 1.5;SCLC-21H: 3.7;SH-SY5Y: 1.6;U-266/70: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076650 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA076650: " "unprognostic (1.86e-2)" "unprognostic (3.09e-4)" "unprognostic (2.79e-1)" "unprognostic (2.96e-7)" "unprognostic (1.11e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-1)" "unprognostic (8.02e-4)" "unprognostic (2.23e-1)" "unprognostic (8.44e-3)" "unprognostic (7.25e-3)" "unprognostic (2.94e-1)" "unprognostic (5.79e-8)" "unprognostic (2.49e-1)" "unprognostic (3.19e-2)" "unprognostic (9.71e-2)" "unprognostic (1.14e-2)" 1.5 0.4 5.1 0.3 5.6 0.2 0.5 9.9 8.0 0.2 0.0 0.2 0.1 0.0 0.1 1.5 0.5 0.3 0.3 4.9 6.5 0.2 0.6 0.1 0.5 3.8 2.1 0.1 0.1 0.0 2.4 0.1 4.0 0.2 0.1 5.2 1.2 0.0 0.5 1.5 0.2 0.0 2.0 0.4 0.2 2.0 3.8 0.7 1.2 0.0 0.9 0.1 0.3 4.3 0.2 0.4 0.1 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.5 0.1 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.4 0.8 0.2 0.2 1.2 1.0 0.1 0.4 0.0 3.7 1.6 0.1 0.2 0.0 0.2 0.2 0.5 0.3 0.1 0.2 0.1 0.1 1.6 0.8 0.2 0.9 0.0 0.0 1.1 0.3 0.2 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.5 0.2 0.3 0.8 0.5 0.1 0.3 0.0 0.3 5.1 5.6 9.9 8.0 4.9 6.5 3.8 2.1 4.0 2.0 3.8 4.3 6.1 6.4 0.5 9.8 0.3 0.0 0.1 0.1 0.0 2.0 0.1 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.1 0.1 0.4 0.0 0.0 113.1 0.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 158.1 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.0 19.7 0.0 11.2 0.0 90.0 37.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.0 1.8 0.0 1.0 0.2 0.4 0.6 0.3 0.1 0.8 0.0 0.0 0.0 0.2 CNIH2 "CNIH-2, Cnil, MGC50896" ENSG00000174871 "Cornichon family AMPA receptor auxiliary protein 2" Q6PI25 11 66278175-66285301 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 270.1" "Cell type enhanced" "Detected in some" "Early spermatids: 75.7;Enteroendocrine cells: 49.6;Excitatory neurons: 17.7;Horizontal cells: 16.8;Late spermatids: 28.1" "Cancer enriched" "Detected in many" 5 "glioma: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.8;AN3-CA: 13.9;MCF7: 13.9;NTERA-2: 15.1;SCLC-21H: 61.5;SH-SY5Y: 28.5;T-47d: 13.3" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.84e-2)" "unprognostic (3.53e-3)" "unprognostic (3.40e-3)" "unprognostic (1.04e-2)" "prognostic unfavorable (9.18e-4)" "unprognostic (1.81e-1)" "unprognostic (1.74e-2)" "unprognostic (3.29e-1)" "unprognostic (3.25e-1)" "unprognostic (3.80e-2)" "unprognostic (7.66e-3)" "unprognostic (4.16e-2)" "unprognostic (6.95e-8)" "unprognostic (3.53e-1)" "unprognostic (3.19e-2)" "unprognostic (3.17e-2)" "unprognostic (3.55e-2)" 0.4 3.3 88.4 0.2 74.6 1.6 0.3 28.8 270.1 0.6 11.0 1.0 0.6 0.4 0.0 0.8 0.6 0.2 0.3 234.9 61.3 0.5 0.4 0.7 0.1 28.3 37.1 0.4 3.4 0.1 45.9 0.5 34.5 0.5 0.2 1.1 0.3 0.0 0.1 1.4 0.6 0.2 30.3 0.6 1.0 5.1 53.4 1.3 0.4 0.0 0.0 0.3 0.5 47.5 0.4 0.8 15.8 13.9 0.2 0.3 2.0 1.0 1.1 2.0 0.1 0.4 0.0 0.1 0.3 0.2 0.9 0.2 3.6 0.0 0.3 1.5 1.4 0.0 0.5 0.0 0.0 0.1 1.1 0.0 0.3 0.1 0.0 0.3 0.0 1.6 0.2 2.1 0.9 13.9 2.1 0.3 15.1 0.0 1.0 6.8 0.0 0.1 0.1 0.8 61.5 28.5 0.1 7.6 0.6 0.7 13.3 0.2 0.0 1.8 0.7 0.5 0.6 0.3 0.4 0.6 4.2 0.4 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 74.6 28.8 270.1 234.9 61.3 28.3 37.1 34.5 30.3 53.4 47.5 0.8 0.0 0.5 2.9 0.2 0.6 0.3 1.4 0.6 2.3 1.6 1.3 0.7 1.5 0.8 0.0 0.0 1.4 0.7 0.1 0.0 0.2 75.7 5.7 0.6 0.4 49.6 0.0 17.7 0.2 1.6 0.7 2.0 0.6 0.0 0.5 0.4 0.1 0.2 16.8 11.7 1.5 0.0 0.0 0.3 28.1 0.6 0.4 0.0 1.9 0.1 0.7 0.0 1.5 2.7 0.6 0.1 0.4 0.9 0.3 0.2 0.2 6.8 2.6 0.0 0.9 0.7 6.0 0.9 0.6 0.4 1.2 1.4 0.1 0.4 0.3 DLGAP1 "DAP-1, GKAP, SAPAP1" ENSG00000170579 "DLG associated protein 1" O14490 18 3496032-4455307 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Group enriched" "Detected in many" 7 "Excitatory neurons: 2145.5;Inhibitory neurons: 3599.2;Oligodendrocyte precursor cells: 1264.6" "Cancer enhanced" "Detected in many" "glioma: 2.4" "Region enhanced" "Detected in many" "cerebral cortex: 39.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 10.7;HAP1: 3.7;U-2197: 3.3;U-87 MG: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078234 Approved Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "HPA078234: " "unprognostic (2.50e-3)" "unprognostic (7.82e-2)" "unprognostic (2.40e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-2)" "unprognostic (3.63e-3)" "unprognostic (2.73e-2)" "unprognostic (1.97e-2)" "unprognostic (2.93e-3)" "unprognostic (5.49e-3)" "unprognostic (5.87e-4)" "unprognostic (2.18e-1)" "unprognostic (2.78e-3)" "unprognostic (3.10e-2)" "unprognostic (4.93e-3)" "unprognostic (8.93e-2)" "unprognostic (9.68e-2)" 0.4 4.3 8.3 0.2 18.3 0.0 1.5 4.4 39.4 0.6 0.0 0.3 0.1 0.7 8.2 0.2 6.5 4.1 0.4 24.0 0.0 1.2 0.1 0.7 0.2 0.0 0.0 1.9 0.2 0.0 2.4 0.6 0.0 2.9 0.2 3.2 1.9 10.1 0.1 0.2 0.2 0.3 0.0 0.5 0.1 3.7 0.0 0.1 0.5 0.4 0.1 0.5 0.6 7.4 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.7 0.0 0.2 1.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.5 0.2 0.0 0.9 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 1.4 0.8 1.2 0.0 0.1 0.0 0.8 0.2 0.0 0.0 0.0 0.0 1.0 3.3 0.0 0.2 0.0 0.1 2.3 0.0 0.9 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 18.3 4.4 39.4 24.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1.5 0.0 4.6 309.8 0.3 0.8 0.3 0.3 5.7 23.6 6.6 2.8 3.1 7.2 0.1 1.8 0.0 0.1 0.1 0.4 0.0 0.2 11.4 31.7 8.3 1.9 3.0 0.0 2145.5 0.2 0.1 1.8 0.5 94.6 0.0 0.0 2.2 0.0 0.2 0.0 3599.2 1.7 0.0 0.0 0.7 13.8 0.6 0.6 12.4 72.1 0.1 0.2 0.0 1264.6 31.0 0.2 0.1 0.4 0.0 3.5 0.0 5.4 4.4 1.4 0.0 0.7 2.2 12.9 4.8 1.6 0.1 0.3 0.8 0.1 0.1 0.1 EFNB3 "EPLG8, LERK-8" ENSG00000108947 "Ephrin B3" Q15768 17 7705202-7711372 "Cancer-related genes, Predicted membrane proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 11.6;Early spermatids: 9.2;Excitatory neurons: 9.1" "Cancer enhanced" "Detected in many" "glioma: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.9;AN3-CA: 32.3;hTERT-RPE1: 32.6;SH-SY5Y: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001623 Approved NA NA 11000 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA001623: AB_1848026" "unprognostic (5.17e-2)" "unprognostic (7.15e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.52e-4)" "unprognostic (3.27e-1)" "unprognostic (1.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.21e-4)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.00e-1)" "unprognostic (8.56e-2)" "unprognostic (2.20e-2)" 3.5 2.0 23.1 0.7 25.8 0.0 3.5 0.1 25.3 7.4 5.6 0.7 0.3 10.3 0.5 2.0 5.5 1.2 1.1 23.0 37.3 1.2 1.7 1.0 0.3 9.2 10.7 4.7 1.2 12.0 5.7 1.2 8.7 2.1 0.6 3.6 1.4 0.5 0.3 5.9 0.9 3.7 5.8 0.1 0.8 3.6 38.2 0.4 0.7 0.1 0.9 1.0 2.4 10.7 0.0 1.0 53.9 32.3 1.0 0.7 0.4 0.6 7.2 4.8 3.1 2.0 3.4 0.0 1.1 2.1 0.3 0.4 13.9 6.9 2.8 0.0 6.8 0.2 0.0 0.1 1.5 0.0 0.0 3.1 1.4 1.5 1.1 32.6 0.3 0.5 0.0 0.0 0.9 5.4 0.0 0.0 4.8 0.0 1.0 0.2 0.1 0.0 7.4 0.7 3.4 28.1 0.0 0.0 1.1 9.4 2.9 0.0 0.1 3.2 10.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 25.8 0.1 25.3 23.0 37.3 9.2 10.7 8.7 5.8 38.2 10.7 2.1 0.0 0.0 1.0 0.2 4.1 3.8 4.6 6.8 2.2 5.9 11.6 1.7 1.5 0.9 0.0 0.0 0.3 0.0 0.1 0.0 1.1 9.2 2.5 5.9 1.3 6.7 2.7 9.1 0.2 1.0 4.6 0.0 0.7 1.3 3.3 2.2 0.0 0.4 5.0 6.8 0.3 4.1 0.0 0.4 5.6 4.7 0.2 0.0 1.0 0.0 1.4 0.0 0.5 1.3 0.2 0.0 3.4 0.0 1.6 0.0 0.0 6.0 0.7 0.0 0.0 2.2 0.7 0.7 1.8 2.8 0.3 0.1 1.2 0.0 1.6 ELAVL2 "HEL-N1, HuB" ENSG00000107105 "ELAV like RNA binding protein 2" Q12926 9 23690104-23826337 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 31.8;testis: 43.1" "Cell type enhanced" "Detected in many" "Early spermatids: 62.2;Excitatory neurons: 135.5;Inhibitory neurons: 390.6;Spermatogonia: 159.2" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 25.4;AF22: 37.2;SCLC-21H: 119.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022222, HPA063001" Enhanced Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB022222: , HPA063001: AB_2684918" "unprognostic (3.51e-1)" "unprognostic (4.18e-2)" "unprognostic (2.05e-1)" "unprognostic (1.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-1)" "unprognostic (4.26e-2)" "unprognostic (8.94e-2)" "unprognostic (3.23e-1)" "unprognostic (1.01e-1)" "unprognostic (9.74e-4)" "unprognostic (3.98e-1)" "unprognostic (9.08e-4)" "unprognostic (8.30e-2)" "unprognostic (1.91e-2)" "unprognostic (2.12e-1)" "unprognostic (2.65e-1)" 0.1 1.3 12.4 0.1 15.8 0.5 0.2 1.5 31.8 0.1 0.0 0.4 0.1 0.5 0.5 0.2 0.1 0.2 0.1 10.9 23.2 0.5 0.0 0.2 0.2 15.7 13.0 1.1 0.0 0.1 1.0 0.1 15.3 0.3 0.5 5.0 0.1 0.1 0.1 0.5 0.2 0.2 0.1 0.1 0.1 43.1 15.0 0.0 0.3 0.0 0.1 0.4 0.2 9.4 25.4 0.3 37.2 0.2 0.1 0.3 0.1 0.3 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 7.8 9.9 15.9 0.2 0.0 7.1 0.0 0.1 0.3 0.0 0.2 0.6 0.5 9.6 0.0 11.0 0.0 0.3 0.1 0.9 1.2 5.3 0.0 0.1 0.1 9.8 0.0 11.8 0.1 13.3 0.2 0.0 0.0 119.6 11.5 0.3 0.3 0.3 9.4 0.6 1.9 0.0 0.2 7.9 0.2 0.2 0.1 0.1 0.1 1.3 0.1 1.4 1.1 0.3 0.5 0.1 0.2 0.2 0.3 0.1 0.1 0.1 0.5 0.3 0.4 1.5 0.4 0.2 0.3 0.2 0.0 12.4 15.8 1.5 31.8 10.9 23.2 15.7 13.0 15.3 0.1 15.0 9.4 0.9 0.0 0.0 7.8 0.0 1.0 0.4 0.4 0.6 8.8 0.9 0.6 0.9 0.0 0.1 0.0 0.0 0.0 0.0 1.4 1.9 0.1 62.2 0.5 0.2 1.8 4.2 0.0 135.5 0.0 0.0 0.8 0.0 0.2 0.0 10.6 0.0 0.0 0.1 16.8 390.6 1.2 0.0 0.0 0.7 39.5 3.1 0.2 0.0 7.5 0.0 2.8 0.0 5.5 5.5 0.0 0.2 1.5 0.0 0.4 0.0 0.1 0.0 10.6 0.0 1.4 1.0 13.9 159.2 0.5 0.9 0.0 0.1 0.7 1.3 0.6 ELFN2 "dJ63G5.3, KIAA1904, LRRC62, PPP1R29" ENSG00000166897 "Extracellular leucine rich repeat and fibronectin type III domain containing 2" Q5R3F8 22 37367960-37427479 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 18.2;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 45.5;Excitatory neurons: 11.6;Inhibitory neurons: 16.2;Oligodendrocyte precursor cells: 36.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 18.2;basal ganglia: 13.8;cerebral cortex: 17.5;hippocampal formation: 16.6;white matter: 4.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 12.0;CAPAN-2: 11.2;GAMG: 12.3;RPMI-8226: 11.7;RPTEC TERT1: 21.5;U-2 OS: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000781 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Vesicles" "HPA000781: AB_1079280" "unprognostic (2.74e-1)" "unprognostic (6.81e-2)" "unprognostic (2.80e-2)" "unprognostic (1.31e-5)" "unprognostic (3.28e-1)" "unprognostic (2.51e-2)" "unprognostic (7.76e-2)" "unprognostic (4.25e-2)" "unprognostic (6.05e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (4.51e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" 0.0 0.6 18.2 0.0 13.8 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 16.6 0.9 0.2 0.2 0.6 0.0 2.7 2.7 0.0 0.2 0.0 0.0 0.0 1.9 0.6 0.0 6.1 0.0 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.1 1.7 2.2 2.2 0.0 0.0 0.0 0.0 0.0 4.8 12.0 4.9 0.0 0.0 0.0 0.9 0.0 5.3 2.8 1.2 0.1 1.9 11.2 0.2 6.8 3.8 12.3 8.2 0.6 1.1 0.1 0.2 0.1 0.0 5.7 0.0 0.2 0.0 0.1 0.9 0.1 0.4 1.6 4.5 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.0 0.3 7.1 10.6 0.1 0.1 11.7 21.5 0.1 1.0 0.0 4.9 6.2 0.0 0.1 0.0 0.1 0.5 0.0 24.1 0.2 3.5 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 13.8 0.0 17.5 16.6 0.9 2.7 2.7 1.9 2.8 2.2 4.8 0.1 0.0 5.1 1.3 0.5 0.1 0.0 0.9 0.0 45.5 0.0 0.0 0.0 1.5 0.2 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.2 0.0 0.0 11.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 3.3 16.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 1.9 0.0 0.9 0.0 36.7 0.9 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.6 2.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FABP6 "I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP" ENSG00000170231 "Fatty acid binding protein 6" P51161 5 160187367-160238735 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 84 "intestine: 4531.3" "Cell type enriched" "Detected in some" 23 "Proximal enterocytes: 52213.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 31.6;EFO-21: 30.5;HDLM-2: 13.6;NB-4: 17.0;RPMI-8226: 17.2;RT4: 15.2;U-2197: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA012601, CAB024713" Enhanced "Intracellular and membrane" NA NA 890000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "CAB024713: , HPA012601: AB_1848435" "unprognostic (3.03e-2)" "unprognostic (7.55e-2)" "unprognostic (1.27e-1)" "unprognostic (5.00e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (5.35e-7)" "unprognostic (3.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.41e-2)" "unprognostic (2.16e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.35e-9)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (2.48e-1)" "unprognostic (1.85e-3)" 0.0 14.4 7.9 2.5 8.1 0.1 0.2 8.3 11.7 3.1 8.7 3.3 4.9 1.9 0.0 1.2 53.9 0.2 2.2 7.4 11.2 0.2 0.1 5.3 4.2 8.9 8.5 0.1 0.1 0.0 0.7 0.1 10.4 0.2 0.0 0.9 0.2 0.2 0.0 0.4 4531.3 3.4 9.4 1.5 0.4 3.1 9.4 5.6 0.1 1.4 3.5 2.7 0.4 7.7 0.3 0.6 0.0 0.2 0.0 0.0 11.4 0.0 0.0 0.0 0.0 8.1 1.3 31.6 30.5 0.0 0.3 0.0 0.0 0.0 0.0 13.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.5 0.0 0.0 2.3 1.2 0.4 0.0 0.0 0.0 17.0 0.1 0.0 2.9 0.0 1.0 17.2 0.0 15.2 2.8 0.7 0.0 8.8 0.2 0.1 0.2 0.2 0.0 0.0 0.1 15.3 1.7 1.7 6.9 4.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 8.1 8.3 11.7 7.4 11.2 8.9 8.5 10.4 9.4 9.4 7.7 0.0 0.0 1.5 1.3 0.2 0.5 0.3 7.8 0.6 0.2 0.1 0.1 3.4 0.0 21.9 0.0 0.0 0.0 0.0 0.6 0.0 0.9 0.4 110.2 0.6 0.1 0.0 0.0 1.6 0.0 0.3 0.6 0.0 1.4 0.0 0.6 0.0 0.0 0.1 1.7 2.2 2244.4 2.0 0.0 4.2 0.2 0.3 0.4 0.0 0.0 0.6 0.2 0.0 0.0 0.9 0.3 2080.0 0.0 0.0 0.1 52213.9 0.1 134.9 0.7 0.0 0.0 1.2 0.1 2.1 2.0 0.1 0.0 0.1 1.7 1304.0 1.4 FBLL1 LOC345630 ENSG00000188573 "Fibrillarin like 1" A6NHQ2 5 168529305-168530634 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Ribonucleoprotein, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 35.4;pituitary gland: 15.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.5;Cone photoreceptor cells: 6.2;Enteroendocrine cells: 6.7;Horizontal cells: 6.7;Inhibitory neurons: 6.6;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 24.2;SH-SY5Y: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049546, HPA077724" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli fibrillar center" Nucleoplasm "HPA049546: AB_2680811, HPA077724: " "unprognostic (2.75e-3)" "unprognostic (2.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "unprognostic (1.26e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (2.45e-1)" "unprognostic (3.80e-3)" "unprognostic (9.69e-2)" "unprognostic (6.55e-3)" "unprognostic (3.15e-1)" "unprognostic (6.18e-2)" "unprognostic (8.32e-2)" "unprognostic (1.22e-1)" 0.2 3.0 22.0 0.1 21.0 0.0 0.6 12.8 35.4 0.5 4.6 0.9 0.4 0.2 0.0 0.2 0.4 0.2 0.3 20.4 32.2 0.6 0.7 0.1 0.0 22.7 21.0 0.7 0.9 0.4 15.5 0.2 26.1 1.0 0.1 1.4 0.9 0.3 0.1 0.5 0.5 0.2 11.4 0.2 0.5 5.9 23.1 0.0 0.2 0.0 0.0 0.3 0.3 20.1 0.0 0.5 1.8 0.3 0.1 0.0 0.9 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.1 0.1 0.5 0.0 1.3 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 20.2 2.1 0.0 1.2 0.0 0.0 1.5 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 21.0 12.8 35.4 20.4 32.2 22.7 21.0 26.1 11.4 23.1 20.1 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.6 8.5 1.4 1.8 1.2 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.4 1.7 0.9 1.4 0.2 6.7 0.0 4.3 0.2 0.1 0.8 0.0 2.4 0.0 1.6 0.0 0.0 0.1 6.7 6.6 0.4 0.0 0.0 0.0 2.3 0.0 0.1 3.6 1.0 0.0 0.7 0.0 3.0 1.1 0.2 0.0 0.0 0.0 0.3 1.0 0.4 0.0 2.8 6.6 0.2 0.4 3.1 0.4 0.2 0.1 0.0 0.1 1.2 0.3 0.0 FSD1 "MGC3213, MIR1" ENSG00000105255 "Fibronectin type III and SPRY domain containing 1" Q9BTV5 19 4304598-4323843 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 16.0;testis: 7.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.6;Distal tubular cells: 15.6;Excitatory neurons: 26.6;Horizontal cells: 16.8;Inhibitory neurons: 19.7;NK-cells: 16.5;Spermatogonia: 30.4" "Group enriched" "Detected in many" 6 "glioma: 9.2;testis cancer: 11.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "MAIT T-cell: 3.6;NK-cell: 5.4;plasmacytoid DC: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 1.4;NK-cells: 5.4;T-cells: 3.6" "Cell line enhanced" "Detected in many" "SCLC-21H: 55.3;SH-SY5Y: 57.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043141 Supported NA NA "Cluster 15: NK-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA043141: AB_10797137" "unprognostic (8.31e-3)" "unprognostic (2.38e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.29e-2)" "unprognostic (9.72e-4)" "unprognostic (1.33e-1)" "unprognostic (9.87e-2)" "unprognostic (1.00e-1)" "unprognostic (3.15e-1)" "unprognostic (8.16e-3)" "unprognostic (1.69e-2)" "unprognostic (3.96e-4)" "unprognostic (1.82e-1)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-1)" 0.3 0.7 11.9 0.7 12.7 0.7 0.0 9.3 15.6 0.6 2.5 0.6 1.0 0.5 0.1 0.2 0.1 0.3 0.1 13.9 12.1 0.3 0.4 0.2 1.1 14.7 10.4 0.2 0.1 0.0 2.0 0.8 16.0 0.3 0.1 1.8 0.1 0.1 0.0 0.2 0.9 0.4 7.7 0.9 0.3 7.6 15.5 0.9 0.1 0.0 0.4 0.1 0.3 11.7 0.1 6.7 18.6 9.7 0.1 1.8 7.9 7.9 3.2 25.0 19.3 15.6 0.5 24.3 6.7 5.5 13.1 1.6 17.0 12.8 8.0 15.6 24.9 6.8 5.6 0.5 9.9 0.0 1.6 4.2 0.1 14.6 0.9 10.1 13.5 21.5 1.1 0.0 1.2 18.4 11.2 0.0 23.9 0.1 12.7 0.0 8.8 0.0 0.1 0.6 55.3 57.6 2.1 0.9 1.7 3.0 0.2 0.2 15.3 3.9 17.6 7.3 7.3 13.7 18.4 6.1 9.4 0.0 9.7 0.0 0.0 0.0 0.5 0.0 3.6 0.0 0.1 0.0 0.0 0.0 0.7 0.2 0.0 5.4 0.0 1.4 0.4 0.7 11.9 12.7 9.3 15.6 13.9 12.1 14.7 10.4 16.0 7.7 15.5 11.7 0.2 0.0 1.1 2.0 0.4 0.1 0.7 0.0 0.0 12.6 0.1 0.0 0.5 0.0 0.6 3.7 2.1 3.2 6.1 0.3 15.6 0.1 4.0 0.1 1.1 0.5 2.4 2.7 26.6 0.0 1.3 1.4 0.5 0.2 2.5 3.5 0.7 0.4 0.8 16.8 19.7 0.4 0.0 0.0 0.0 5.3 0.9 0.3 0.0 3.7 0.1 1.7 16.5 8.5 9.5 0.0 0.1 0.4 0.5 0.3 0.0 0.3 0.0 7.1 0.0 0.9 1.6 3.7 30.4 0.0 0.0 2.7 5.6 0.1 0.3 0.4 GABRA4 ENSG00000109158 "Gamma-aminobutyric acid type A receptor subunit alpha4" P48169 4 46918900-46993581 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 7.5;heart muscle: 2.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 124.9;Inhibitory neurons: 160.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 149 "REH: 14.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.78e-2)" "unprognostic (6.57e-3)" "unprognostic (2.46e-1)" "unprognostic (2.23e-1)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "unprognostic (6.91e-2)" 0.0 0.0 1.8 0.0 7.5 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 2.5 4.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 7.5 0.0 6.8 4.0 2.6 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 21.5 0.0 0.5 0.0 0.0 0.6 0.3 0.0 0.6 15.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 124.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 160.1 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 8.4 0.0 6.1 0.0 3.5 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.4 3.8 0.1 0.4 0.1 0.0 0.0 0.0 0.9 0.0 GABRB3 ENSG00000166206 "Gamma-aminobutyric acid type A receptor subunit beta3" P28472 15 26543546-26939539 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.5;retina: 31.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 152.4;Excitatory neurons: 519.6;Inhibitory neurons: 258.7;Oligodendrocyte precursor cells: 139.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 68.5;HAP1: 27.9;NTERA-2: 48.3;OE19: 21.6;SCLC-21H: 44.2;U-2 OS: 18.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.72e-1)" "unprognostic (4.91e-2)" "unprognostic (3.20e-2)" "unprognostic (4.25e-2)" "unprognostic (1.66e-1)" "unprognostic (7.07e-2)" "unprognostic (1.00e-1)" "unprognostic (8.87e-2)" "unprognostic (1.02e-1)" "unprognostic (2.44e-1)" "unprognostic (1.44e-2)" "unprognostic (3.62e-1)" "unprognostic (3.56e-3)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (3.33e-2)" "unprognostic (4.05e-1)" 0.6 5.5 16.6 0.5 24.3 0.0 0.8 3.9 29.5 2.3 0.0 1.2 0.8 1.7 1.0 1.2 2.3 13.6 6.2 28.0 18.0 7.3 0.9 0.9 0.1 0.0 1.3 1.9 4.8 2.1 15.7 0.0 0.3 5.0 0.9 31.9 0.5 1.2 0.1 0.7 0.6 1.4 3.1 0.6 5.7 4.0 11.6 1.5 8.7 0.1 0.2 1.1 0.5 13.8 0.0 68.5 10.7 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 27.9 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.0 5.4 3.3 0.0 0.0 0.0 0.0 0.0 14.8 2.1 0.1 0.0 0.0 4.8 0.0 48.3 21.6 3.4 0.0 0.0 0.0 4.7 0.0 44.2 16.6 0.0 0.1 0.0 5.0 0.1 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 24.3 3.9 29.5 28.0 18.0 0.0 1.3 0.3 3.1 11.6 13.8 0.4 12.8 3.6 33.3 0.0 0.0 0.8 0.7 1.2 152.4 1.0 0.8 15.3 24.3 1.7 5.5 39.6 0.4 0.0 1.4 0.0 4.6 10.7 1.4 4.0 1.2 10.3 0.0 519.6 0.4 0.0 1.7 2.6 0.6 0.0 1.1 0.7 0.4 0.0 75.7 258.7 1.9 0.0 0.6 0.0 5.6 1.8 0.0 0.0 5.6 0.2 7.9 0.0 139.7 8.7 1.7 0.4 3.4 0.0 3.3 0.2 7.0 13.5 53.7 0.0 1.0 0.9 8.6 29.3 0.7 0.1 0.3 0.1 0.5 0.9 0.4 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "brain: 645.9;pituitary gland: 885.8" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 22.2;Ductal cells: 38.9;Endometrial ciliated cells: 64.2;Endometrial stromal cells: 50.8;Exocrine glandular cells: 52.1;Extravillous trophoblasts: 48.7;Glandular and luminal cells: 26.4;Pancreatic endocrine cells: 39.5;Prostatic glandular cells: 82.5;Urothelial cells: 24.3" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in many" 13 "hypothalamus: 645.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 267.2;HEK 293: 119.3;K-562: 139.5;NB-4: 493.5;SH-SY5Y: 189.6" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 60000 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 24: NB-4 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 3.2 0.9 2.8 14.9 2.1 0.7 4.4 1.1 5.2 1.0 0.8 17.6 1.8 0.2 0.0 0.8 1.0 0.2 1.0 2.2 645.9 1.5 0.3 0.5 0.1 48.5 5.1 0.2 2.1 0.1 885.8 0.3 13.8 4.4 4.0 0.0 0.9 0.2 0.4 33.3 4.1 9.9 0.6 0.3 9.7 1.0 19.5 0.7 0.4 0.0 0.0 0.7 2.9 2.6 0.0 11.0 1.1 0.3 0.0 0.0 24.0 36.7 0.0 0.7 0.0 267.2 9.9 0.0 12.7 1.3 0.4 0.1 0.0 0.2 0.0 0.0 119.3 6.4 74.6 0.0 1.3 3.7 0.0 1.7 4.0 0.0 0.1 0.0 6.3 0.0 139.5 0.0 0.2 77.2 0.0 493.5 60.3 2.9 23.7 0.0 0.1 51.1 0.6 0.0 49.8 189.6 25.8 1.5 0.0 26.8 1.5 57.6 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.1 1.1 5.2 2.2 645.9 48.5 5.1 13.8 0.6 19.5 2.6 0.6 0.0 0.0 0.0 0.2 2.0 22.2 0.1 0.0 0.0 3.2 5.8 1.4 0.0 0.0 0.0 0.0 0.6 0.1 0.7 0.0 38.9 0.1 64.2 50.8 3.4 1.8 4.2 2.1 52.1 48.7 6.6 2.0 26.4 4.5 0.4 0.0 0.0 2.0 0.0 0.2 1.1 4.1 0.0 1.2 0.2 0.0 0.7 1.8 0.0 0.6 0.0 0.0 0.0 0.3 39.5 0.1 0.0 1.0 82.5 0.0 0.4 0.0 0.0 0.0 1.6 6.7 2.2 10.9 1.1 3.4 1.9 0.8 0.0 1.3 24.3 GDAP1 "CMT2K, CMT4, CMT4A" ENSG00000104381 "Ganglioside induced differentiation associated protein 1" Q8TB36 8 74320613-74518007 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 46.9;Cone photoreceptor cells: 47.9;Excitatory neurons: 75.7;Horizontal cells: 47.1;Inhibitory neurons: 67.3;Oligodendrocyte precursor cells: 67.8;Rod photoreceptor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 38.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014266, HPA024334" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Mitochondria Cytosol "HPA014266: AB_1849581, HPA024334: AB_1849583" "unprognostic (3.19e-2)" "unprognostic (1.52e-3)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (3.31e-1)" "unprognostic (4.36e-2)" "unprognostic (1.72e-2)" "prognostic favorable (2.68e-4)" "unprognostic (3.88e-1)" "unprognostic (4.17e-1)" "unprognostic (9.44e-3)" "unprognostic (2.44e-1)" "unprognostic (5.40e-2)" "unprognostic (3.29e-1)" "unprognostic (6.99e-2)" "prognostic unfavorable (4.54e-4)" "unprognostic (2.73e-1)" 2.7 9.6 19.0 3.3 22.5 1.2 4.0 15.2 26.0 2.9 4.9 2.5 2.4 3.9 1.9 4.0 2.8 2.5 2.1 25.3 19.7 4.2 1.5 2.4 3.3 14.5 17.0 6.0 7.4 12.4 20.6 1.2 18.1 4.1 2.4 19.0 2.4 4.1 2.7 1.7 2.3 2.8 12.2 1.9 2.0 4.7 16.7 4.5 6.6 3.1 2.8 3.9 2.6 20.5 3.5 16.8 17.7 4.8 1.2 1.6 1.5 1.8 8.2 8.3 9.5 7.8 5.0 14.8 2.5 1.2 10.6 6.6 12.4 7.0 16.2 19.7 3.6 7.4 8.9 14.0 0.7 7.6 15.8 4.7 2.3 5.3 8.2 0.9 1.1 7.3 3.4 0.3 4.8 5.7 12.6 0.4 20.1 24.5 17.9 8.7 9.2 3.2 2.9 15.3 18.2 38.9 13.1 3.4 9.7 4.9 14.9 2.6 0.0 11.7 6.2 2.9 5.5 9.3 15.7 6.8 7.3 0.3 13.8 0.5 0.9 1.0 0.8 3.1 1.0 1.4 0.8 1.3 0.8 1.3 0.6 0.6 1.8 0.7 5.5 0.2 4.0 0.8 19.0 22.5 15.2 26.0 25.3 19.7 14.5 17.0 18.1 12.2 16.7 20.5 6.4 6.4 5.1 27.1 5.9 1.8 7.4 4.2 6.2 46.9 6.2 6.1 5.9 5.7 3.6 3.7 47.9 0.4 3.9 2.1 9.8 5.2 5.4 15.4 7.0 6.7 20.4 2.1 75.7 5.8 0.3 4.8 3.1 2.8 17.2 2.1 6.4 1.8 4.7 47.1 67.3 1.7 12.2 6.3 2.5 1.3 4.1 4.6 1.8 15.0 2.9 23.5 4.1 67.8 41.9 3.7 1.4 5.7 2.6 2.6 3.6 6.6 4.9 47.7 0.0 8.0 5.5 14.7 13.1 3.7 1.3 0.0 3.1 6.5 1.7 3.8 GPR158 KIAA1136 ENSG00000151025 "G protein-coupled receptor 158" Q5T848 10 25174802-25602229 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 24.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 367.4;Horizontal cells: 144.7;Inhibitory neurons: 301.9;Oligodendrocyte precursor cells: 419.7;Oligodendrocytes: 101.6" "Cancer enhanced" "Detected in many" "glioma: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEL: 21.3;T-47d: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013185 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013185: AB_2113957" "unprognostic (4.43e-2)" "unprognostic (3.14e-2)" "unprognostic (7.42e-2)" "unprognostic (2.66e-5)" "unprognostic (5.67e-2)" "unprognostic (9.37e-2)" "unprognostic (4.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (8.09e-3)" "unprognostic (1.72e-1)" "unprognostic (2.60e-6)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (3.90e-1)" 0.0 0.7 2.6 0.1 12.7 0.0 0.0 24.9 8.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 2.4 0.0 0.0 0.0 0.0 8.5 4.7 0.0 0.0 0.2 1.4 0.3 8.8 0.1 0.1 4.5 0.0 0.2 0.0 0.0 0.2 0.0 2.3 0.0 0.1 0.5 7.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.0 0.0 0.0 0.0 2.6 0.0 21.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.5 0.0 0.3 0.2 0.0 0.0 1.2 0.0 0.5 1.1 1.9 0.0 5.6 0.0 0.0 0.0 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 12.7 24.9 8.6 3.5 2.4 8.5 4.7 8.8 2.3 7.0 4.3 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 19.9 0.0 0.1 0.1 0.0 0.0 367.4 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 144.7 301.9 0.0 0.0 0.0 0.0 12.0 0.0 0.1 0.0 10.3 0.0 26.2 0.0 419.7 101.6 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 3.8 0.0 0.1 0.1 1.8 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 GPR19 ENSG00000183150 "G protein-coupled receptor 19" Q15760 12 12660890-12696207 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.3;pituitary gland: 7.8" "Cell type enhanced" "Detected in some" "Astrocytes: 7.8;Excitatory neurons: 15.2;Inhibitory neurons: 15.6;Oligodendrocyte precursor cells: 15.6;Oligodendrocytes: 5.9" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.5" "Group enriched" "Detected in many" 15 "granulocytes: 2.9;T-cells: 6.5" "Cell line enhanced" "Detected in many" "HDLM-2: 39.9;NTERA-2: 39.7;SuSa: 28.5;WM-115: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013955 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013955: AB_1849287" "unprognostic (1.92e-1)" "unprognostic (3.38e-2)" "unprognostic (1.72e-1)" "unprognostic (8.62e-5)" "unprognostic (1.60e-1)" "unprognostic (3.21e-1)" "unprognostic (8.25e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "unprognostic (6.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.70e-2)" "unprognostic (2.67e-12)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (1.60e-1)" 0.3 0.8 7.2 2.0 7.3 0.9 0.3 9.1 10.3 0.1 3.6 0.5 0.3 0.1 0.1 0.5 0.2 0.3 0.1 7.0 9.1 0.1 0.2 0.2 1.8 6.3 6.8 0.0 0.3 0.1 7.8 0.3 6.9 0.1 0.6 2.0 0.1 0.1 0.0 0.8 0.5 0.3 7.0 0.7 0.4 4.3 7.6 2.8 0.1 0.0 2.4 0.3 0.1 6.9 1.6 0.6 16.6 0.4 0.0 0.0 7.0 1.6 1.7 2.9 2.5 6.6 10.1 6.8 2.5 1.2 2.3 1.3 2.7 0.3 4.8 39.9 0.3 1.6 0.7 1.1 0.0 1.7 0.6 0.1 0.0 3.1 1.9 1.2 0.5 0.7 0.3 13.8 0.6 2.4 0.6 1.0 39.7 1.7 3.0 4.4 2.5 0.2 0.2 1.4 5.4 5.0 0.7 1.4 13.4 28.5 0.9 1.7 0.0 0.8 7.2 1.3 3.9 7.6 7.2 13.3 3.1 4.7 20.4 0.0 0.0 0.0 1.2 0.0 0.8 0.2 2.4 1.4 0.0 0.1 0.4 0.9 2.9 0.3 0.0 0.0 6.5 0.3 7.2 7.3 9.1 10.3 7.0 9.1 6.3 6.8 6.9 7.0 7.6 6.9 0.2 0.0 0.0 7.8 0.4 0.1 0.1 0.0 0.0 1.8 0.4 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 4.7 0.1 0.2 0.1 0.0 2.7 15.2 0.0 0.3 0.1 0.0 0.1 0.0 0.2 0.4 0.2 0.1 0.0 15.6 0.1 0.0 0.3 0.3 1.6 0.3 0.2 0.0 2.8 0.0 1.7 0.0 15.6 5.9 0.2 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.8 3.6 0.6 0.0 0.0 0.1 1.2 0.0 0.3 0.1 GPR22 ENSG00000172209 "G protein-coupled receptor 22" Q99680 7 107470018-107475684 "G-protein coupled receptors, Predicted membrane proteins" "Cilium biogenesis/degradation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;cervix: 2.1;heart muscle: 8.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Cardiomyocytes: 57.9;Excitatory neurons: 49.9;Inhibitory neurons: 51.2;Oligodendrocyte precursor cells: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 27 "SH-SY5Y: 2.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 60.4" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.23e-2)" "unprognostic (1.25e-2)" "unprognostic (1.19e-1)" "unprognostic (5.52e-2)" "unprognostic (7.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.27e-3)" "unprognostic (1.62e-1)" "unprognostic (8.76e-3)" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (5.85e-4)" "unprognostic (1.55e-1)" "unprognostic (7.53e-3)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" 0.0 0.9 1.0 0.0 1.9 0.0 0.0 2.5 2.7 2.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 8.2 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.9 2.5 2.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 3.9 0.1 0.3 0.0 0.0 0.0 15.3 0.0 0.0 57.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.5 1.8 0.4 0.0 0.0 49.9 0.0 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.0 0.1 5.0 51.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 6.5 0.0 0.7 0.0 12.5 7.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.6 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 HS3ST4 3OST4 ENSG00000182601 "Heparan sulfate-glucosamine 3-sulfotransferase 4" Q9Y661 16 25691959-26137685 "Enzymes, Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 38.1" "Group enriched" "Detected in some" 9 "Excitatory neurons: 431.4;Microglial cells: 536.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.09e-2)" "unprognostic (1.87e-1)" "unprognostic (2.95e-1)" "unprognostic (2.24e-1)" "unprognostic (1.43e-3)" "unprognostic (1.27e-1)" "unprognostic (3.84e-1)" "unprognostic (8.81e-3)" "unprognostic (6.71e-2)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.51e-2)" "unprognostic (3.67e-2)" 0.0 0.0 19.0 0.0 17.5 0.0 2.2 7.0 15.8 0.3 3.3 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 33.2 12.2 0.0 0.0 0.0 0.0 18.2 11.8 0.0 0.0 3.6 0.3 0.0 19.0 0.8 0.0 2.0 0.1 0.0 0.0 0.5 0.0 0.0 7.5 1.6 1.7 0.5 38.1 0.2 0.0 0.0 0.0 0.2 0.5 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 17.5 7.0 15.8 33.2 12.2 18.2 11.8 19.0 7.5 38.1 18.5 0.0 0.0 0.0 7.5 0.1 0.0 0.4 0.1 0.0 26.0 2.6 2.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 431.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 536.8 0.0 0.4 0.0 6.6 9.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 HTR5A 5-HT5A ENSG00000157219 "5-hydroxytryptamine receptor 5A" P47898 7 155070324-155087392 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.6" "Group enriched" "Detected in some" 4 "Early spermatids: 8.7;Excitatory neurons: 7.6;Inhibitory neurons: 10.0;Late spermatids: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB017467 Approved NA NA "Cluster 6: Brain - Smell perception" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB017467: AB_2122566" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" 0.0 0.0 1.7 0.0 1.6 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.6 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 3.6 2.8 1.3 1.6 0.6 2.7 1.8 0.2 1.2 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNA4 "HK1, HPCN2, KCNA4L, Kv1.4" ENSG00000182255 "Potassium voltage-gated channel subfamily A member 4" P22459 11 30009730-30017030 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cataract, Disease variant, Dystonia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 6.1;brain: 20.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.7;Excitatory neurons: 8.2;Horizontal cells: 13.5;Muller glia cells: 6.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 20.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB001977, HPA016422" Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 62: Horizontal cells - Visual perception" "CAB001977: , HPA016422: AB_1855574" "unprognostic (1.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" "unprognostic (6.71e-2)" "unprognostic (1.17e-1)" 1.5 6.1 4.7 0.0 20.0 0.0 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 4.7 4.4 0.2 0.0 0.7 0.0 1.6 1.7 0.0 0.0 0.0 1.3 0.2 1.3 0.0 0.0 1.9 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 20.0 0.0 6.5 4.7 4.4 1.6 1.7 1.3 0.1 6.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 8.2 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.5 2.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.4 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNH5 "eag2, H-EAG2, hEAG2, Kv10.2" ENSG00000140015 "Potassium voltage-gated channel subfamily H member 5" Q8NCM2 14 62699464-63102037 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 8.5;retina: 4.5" "Group enriched" "Detected in some" 16 "Bipolar cells: 62.2;Excitatory neurons: 185.0;Inhibitory neurons: 74.4;Oligodendrocyte precursor cells: 65.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 7.2;RT4: 10.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030487, HPA072351" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 58: Brain - Synaptic function" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "Nucleoplasm, Cytosol" "HPA030487: AB_10609995, HPA072351: " "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" "unprognostic (1.25e-1)" "unprognostic (4.23e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-2)" "unprognostic (8.45e-2)" "unprognostic (2.66e-1)" "unprognostic (1.70e-3)" "unprognostic (3.11e-1)" 0.2 1.0 2.4 0.0 2.1 0.0 0.0 0.0 5.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 1.8 0.0 0.0 0.0 0.0 2.9 3.3 0.0 0.0 0.0 0.3 0.2 3.0 0.1 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 8.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.8 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.1 0.0 5.9 4.5 1.8 2.9 3.3 3.0 0.8 8.5 1.2 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 62.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 5.8 0.1 0.2 0.2 0.0 0.0 185.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 74.4 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.8 0.0 0.5 0.0 65.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.6 0.0 0.0 0.1 1.6 1.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 KCNK10 "K2p10.1, PPP1R97, TREK-2, TREK2" ENSG00000100433 "Potassium two pore domain channel subfamily K member 10" P57789 14 88180103-88326907 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;intestine: 5.1;stomach 1: 2.6" "Group enriched" "Detected in some" 4 "dendritic cells: 12.5;Excitatory neurons: 43.8;Inhibitory neurons: 17.0;Oligodendrocyte precursor cells: 37.7;Oligodendrocytes: 11.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 62 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in single" 100 "dendritic cells: 10.0" "Cell line enhanced" "Detected in some" "OE19: 1.5;REH: 1.7;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030462 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA030462: AB_10601919" "unprognostic (9.52e-3)" "unprognostic (1.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.08e-1)" "unprognostic (8.20e-2)" "unprognostic (1.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-1)" "unprognostic (4.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.45e-1)" "unprognostic (6.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-1)" "unprognostic (4.26e-3)" 0.0 0.3 4.0 0.4 3.6 0.2 0.0 5.1 4.1 0.2 0.0 1.3 5.1 0.0 0.0 1.1 0.0 0.0 0.0 4.4 2.9 2.4 0.0 0.1 0.1 4.2 2.9 0.0 1.4 0.0 0.5 0.0 3.5 0.0 0.7 0.1 0.2 0.0 0.0 0.0 2.6 0.1 2.3 0.1 2.6 0.5 2.4 0.0 0.0 0.0 0.4 0.0 0.2 4.6 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.1 1.7 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.1 4.0 3.6 5.1 4.1 4.4 2.9 4.2 2.9 3.5 2.3 2.4 4.6 0.0 0.0 0.0 0.7 0.1 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 12.5 2.1 0.0 0.0 0.7 0.0 0.0 0.1 1.8 0.0 43.8 0.6 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.0 1.6 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 37.7 11.9 0.1 0.3 0.0 0.0 0.0 1.5 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.2 0.0 0.0 0.1 0.0 1.6 0.1 KCNK17 "K2p17.1, TALK-2, TALK2, TASK-4, TASK4" ENSG00000124780 "Potassium two pore domain channel subfamily K member 17" Q96T54 6 39299001-39314461 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 7.7;thyroid gland: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 11.0;Exocrine glandular cells: 7.9;granulocytes: 6.3;Microglial cells: 17.8;Smooth muscle cells: 5.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 63.8" "Lineage enriched" "Detected in many" 34 "dendritic cells: 63.8" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 83.8" "Not detected" "Not detected" HPA043892 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA043892: AB_10962838" "unprognostic (5.33e-3)" "unprognostic (6.42e-2)" "unprognostic (1.33e-1)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "unprognostic (4.09e-2)" "unprognostic (4.95e-1)" "unprognostic (2.35e-1)" "unprognostic (1.71e-2)" "unprognostic (2.54e-1)" "unprognostic (3.77e-11)" "unprognostic (5.89e-2)" "unprognostic (5.36e-1)" "unprognostic (2.82e-1)" "unprognostic (3.86e-3)" 0.5 0.3 0.3 0.4 0.4 1.2 0.8 0.3 0.6 0.7 0.2 0.6 1.9 1.2 0.0 0.3 0.8 2.5 5.8 0.2 0.3 0.1 4.0 7.7 0.7 0.4 0.5 0.2 3.9 0.1 1.8 4.0 0.3 0.6 0.5 0.0 0.7 0.2 0.1 0.1 1.1 1.0 0.2 0.7 2.9 0.2 0.5 1.3 6.5 0.5 1.1 0.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 63.8 0.0 0.3 0.3 0.4 0.3 0.6 0.2 0.3 0.4 0.5 0.3 0.2 0.5 0.3 0.0 0.0 2.6 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.9 0.3 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 7.9 0.0 1.8 1.1 0.1 6.3 0.0 0.7 0.2 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.9 0.0 17.8 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.0 KIF5A "D12S1889, MY050, NKHC, SPG10" ENSG00000155980 "Kinesin family member 5A" Q12840 12 57546026-57586633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Amyotrophic lateral sclerosis, Disease variant, Epilepsy, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "brain: 1628.2;choroid plexus: 951.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 40.7;Early spermatids: 12.2;Endometrial stromal cells: 12.9;Excitatory neurons: 28.4;Horizontal cells: 26.9;Inhibitory neurons: 21.7;Late spermatids: 15.2;Rod photoreceptor cells: 11.3" "Cancer enriched" "Detected in some" 5 "glioma: 26.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 33.2;K-562: 15.3;NTERA-2: 17.7;SCLC-21H: 34.4;U-87 MG: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004469, HPA073448" Enhanced Approved "Nucleoplasm,Mitotic spindle,Cytosol" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "Mitotic spindle" "HPA004469: AB_1079212, HPA073448: AB_2686601" "unprognostic (7.94e-2)" "unprognostic (4.95e-3)" "unprognostic (3.87e-1)" "unprognostic (3.34e-3)" "unprognostic (7.12e-2)" "unprognostic (4.22e-2)" "unprognostic (3.22e-5)" "unprognostic (2.82e-1)" "unprognostic (2.01e-1)" "unprognostic (1.52e-2)" "prognostic favorable (5.23e-4)" "unprognostic (7.61e-2)" "unprognostic (2.26e-4)" "unprognostic (4.75e-2)" "unprognostic (1.46e-1)" "unprognostic (4.12e-1)" "unprognostic (1.51e-1)" 0.4 10.6 1198.6 4.6 1243.7 4.2 0.5 1056.4 1628.2 2.5 951.3 4.5 3.6 3.8 1.4 1.4 0.6 0.7 0.6 1242.7 1056.4 0.8 0.2 0.8 0.7 1103.5 1046.7 0.6 2.6 9.0 21.3 0.1 1113.3 0.9 1.9 48.0 1.1 0.6 0.3 1.1 2.5 2.0 1002.7 0.8 1.3 4.8 1052.3 0.1 2.3 0.1 0.4 0.5 1.5 1313.2 0.5 0.1 7.2 5.7 0.0 0.0 0.6 1.4 1.3 2.2 3.5 1.2 0.2 3.2 0.4 1.9 1.3 0.8 3.8 0.1 2.5 33.2 4.1 0.5 1.8 7.0 1.9 1.5 1.3 1.0 0.4 1.6 0.1 0.5 0.5 2.8 15.3 9.4 0.0 0.6 0.8 0.0 17.7 0.0 0.0 0.5 0.2 0.3 1.1 0.5 34.4 9.1 0.0 1.6 0.0 2.0 0.9 0.2 0.9 0.6 5.3 1.1 2.1 5.3 7.7 1.9 14.5 0.1 0.6 0.2 0.4 0.1 1.0 0.5 1.6 0.7 0.7 1.2 0.3 0.5 0.9 2.2 1.1 0.3 1.1 0.3 1.0 0.4 1198.6 1243.7 1056.4 1628.2 1242.7 1056.4 1103.5 1046.7 1113.3 1002.7 1052.3 1313.2 0.1 0.0 0.0 2.9 0.1 0.0 0.1 0.0 0.0 40.7 0.1 0.9 2.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.0 12.2 0.5 12.9 0.7 0.0 0.4 28.4 0.2 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 26.9 21.7 0.2 0.0 0.0 0.2 15.2 0.0 0.1 0.0 0.0 0.0 6.4 0.0 8.5 3.9 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.7 3.3 7.9 0.0 0.1 0.0 0.3 0.0 0.1 0.1 KNDC1 "bB439H18.3, C10orf23, FLJ25027, KIAA1768, RASGEF2, v-KIND, Very-KIND" ENSG00000171798 "Kinase non-catalytic C-lobe domain containing 1" Q76NI1 10 133160219-133226412 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.0;pituitary gland: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 93.4;Excitatory neurons: 41.9;Inhibitory neurons: 36.3;Respiratory ciliated cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;EFO-21: 1.2;MCF7: 1.1;NTERA-2: 1.4;RPMI-8226: 2.1;SuSa: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039624, HPA056143" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" Vesicles "HPA039624: AB_10671045, HPA056143: " "unprognostic (2.32e-1)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (1.59e-3)" "unprognostic (1.96e-2)" "unprognostic (2.76e-1)" "unprognostic (5.61e-2)" "unprognostic (2.75e-2)" "unprognostic (6.77e-2)" "unprognostic (1.15e-1)" "unprognostic (6.80e-3)" "unprognostic (2.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (1.94e-1)" "unprognostic (9.41e-2)" 1.5 13.7 31.1 0.1 17.9 0.0 0.2 8.4 44.0 2.3 0.0 0.3 0.0 2.8 0.7 0.2 9.0 0.2 0.3 19.8 9.1 0.8 6.5 2.8 0.0 17.3 13.3 8.5 0.5 0.4 27.5 0.4 10.3 1.1 0.0 0.9 0.6 0.9 0.0 0.2 0.2 0.4 3.0 0.5 0.3 1.8 22.7 0.0 2.5 0.0 0.0 0.2 0.9 13.1 0.2 0.3 0.2 1.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.2 0.0 1.2 0.1 0.5 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 31.1 17.9 8.4 44.0 19.8 9.1 17.3 13.3 10.3 3.0 22.7 13.1 0.0 0.0 9.0 93.4 0.2 0.0 0.1 0.4 0.0 1.6 0.2 0.0 2.4 1.5 4.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 14.2 1.5 0.2 3.0 0.0 41.9 0.0 0.1 1.4 0.0 0.3 0.0 1.5 0.4 4.6 0.2 1.7 36.3 0.0 0.0 1.0 0.4 1.0 3.7 1.2 0.0 5.6 0.3 4.5 0.0 6.6 2.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 25.9 1.0 0.0 0.1 0.5 0.0 1.7 0.0 0.3 0.1 0.4 1.2 0.0 0.0 KSR2 FLJ25965 ENSG00000171435 "Kinase suppressor of ras 2" Q6VAB6 12 117453012-117968990 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.0;pituitary gland: 7.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 161.8;Excitatory neurons: 284.7;Inhibitory neurons: 234.9;Oligodendrocyte precursor cells: 95.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 4.5;SCLC-21H: 3.2;TIME: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035536 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA035536: AB_10673485" "unprognostic (1.74e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (2.29e-2)" "unprognostic (9.11e-2)" "unprognostic (8.42e-2)" "unprognostic (6.91e-3)" "unprognostic (1.10e-2)" "unprognostic (5.78e-2)" "unprognostic (5.80e-2)" "unprognostic (2.05e-4)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (5.02e-2)" "unprognostic (5.68e-2)" "unprognostic (8.14e-3)" "unprognostic (5.74e-2)" 0.0 0.9 2.3 0.0 2.4 0.0 0.2 1.1 10.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.2 0.0 0.0 7.7 0.0 0.7 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.6 7.9 0.0 0.6 0.1 0.3 1.9 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.8 0.3 0.0 0.6 0.0 0.1 0.2 0.0 2.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.1 0.4 0.9 3.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 6.9 0.0 0.5 0.0 0.1 0.5 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.4 1.1 10.0 7.7 0.0 0.7 0.0 0.6 0.1 0.3 2.7 0.9 0.0 0.0 17.6 0.5 0.3 1.2 0.1 0.0 55.2 2.8 2.4 2.2 5.7 0.2 161.8 39.6 0.9 0.0 1.3 0.0 2.3 10.8 4.0 0.3 0.5 20.4 5.3 284.7 1.5 0.4 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.1 47.1 234.9 10.3 2.0 0.3 0.4 12.5 0.0 0.0 0.0 5.6 0.0 2.4 0.0 95.0 4.2 0.4 1.5 0.0 0.0 1.4 0.1 0.8 0.3 28.2 0.0 0.3 0.1 0.6 3.1 0.0 0.3 0.3 0.6 0.0 3.0 1.3 LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513935 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 44.0" "Cell type enhanced" "Detected in many" "Club cells: 41.4;Excitatory neurons: 37.0;Inhibitory neurons: 38.8;Urothelial cells: 49.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 9.4;SK-BR-3: 16.4;U-266/70: 9.8;U-266/84: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Supported Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: AB_2732330" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" 0.0 1.7 23.1 0.7 27.5 0.4 0.7 6.1 44.0 0.6 0.0 0.2 3.7 0.1 1.1 0.6 0.3 0.4 0.3 31.7 6.7 1.1 0.0 1.3 1.1 9.9 1.2 0.1 0.8 3.6 5.7 0.6 1.5 1.5 0.0 2.7 2.6 1.1 0.0 0.8 1.9 0.0 0.7 0.6 1.2 0.2 8.4 0.4 0.8 0.0 0.8 0.2 0.0 21.8 6.0 4.4 0.5 0.5 0.0 0.0 5.1 0.1 0.4 0.0 0.2 3.7 5.2 1.6 1.5 0.0 1.4 3.0 0.8 1.9 0.0 0.7 2.8 0.2 2.5 0.9 0.0 0.0 9.4 0.1 1.1 0.3 0.0 2.0 0.0 5.0 1.6 3.6 0.0 7.9 1.1 4.1 1.2 3.4 1.5 4.8 0.0 2.1 1.7 1.2 1.5 2.9 0.2 16.4 0.9 1.2 5.6 0.2 0.1 0.0 1.5 0.1 0.0 9.8 9.3 1.9 0.3 4.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.0 23.1 27.5 6.1 44.0 31.7 6.7 9.9 1.2 1.5 0.7 8.4 21.8 0.3 3.2 1.7 11.8 2.1 0.5 13.1 17.0 2.8 15.9 20.5 6.2 2.7 2.8 41.4 7.3 0.0 4.9 0.6 0.4 25.4 21.5 0.1 8.4 0.6 0.5 0.0 0.0 37.0 0.4 2.8 0.9 6.6 8.1 0.0 0.6 1.4 0.4 1.3 18.5 38.8 1.2 8.2 0.6 0.9 0.2 0.6 0.4 3.6 1.9 0.2 6.9 0.0 26.2 9.6 17.2 0.1 0.0 14.5 18.8 3.0 0.6 25.9 2.2 0.0 0.4 3.3 4.0 3.3 7.1 1.8 6.8 1.3 2.9 1.5 49.5 MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 166.8;pituitary gland: 118.2" "Cell type enhanced" "Detected in many" "Early spermatids: 43.8;Enteroendocrine cells: 40.2;Horizontal cells: 67.3;Late spermatids: 39.2;Muller glia cells: 41.3;Oligodendrocytes: 48.7" "Cancer enhanced" "Detected in all" "glioma: 51.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332, HPA079657" Approved Enhanced "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA058921: AB_2683854, HPA070332: AB_2686254, HPA079657: " "unprognostic (3.96e-2)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (6.88e-2)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (8.25e-3)" "unprognostic (3.42e-3)" "unprognostic (1.27e-2)" "unprognostic (9.54e-2)" "unprognostic (3.22e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.23e-11)" "unprognostic (7.19e-2)" "unprognostic (4.01e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-3)" 4.8 23.3 127.9 2.3 131.0 1.3 4.8 122.0 147.7 8.2 29.6 8.3 1.4 10.9 3.5 2.2 11.3 3.5 5.5 166.8 120.6 11.5 5.6 4.0 0.6 154.9 130.9 9.1 43.1 19.2 118.2 1.4 142.6 11.6 1.2 11.5 11.4 6.1 2.4 4.0 3.7 5.7 124.6 2.3 9.0 27.7 139.3 1.0 7.0 2.5 0.4 6.7 4.8 164.4 0.0 7.1 9.4 26.2 3.4 1.8 0.3 5.1 4.6 9.9 7.2 6.3 1.1 0.4 2.5 5.9 16.8 5.8 10.2 4.8 4.4 4.0 13.1 0.1 8.6 4.1 3.1 0.6 4.4 2.4 1.0 6.4 1.3 6.6 2.2 0.9 11.5 1.6 2.8 3.9 0.4 0.6 24.9 3.3 10.5 0.6 15.4 0.3 4.6 0.2 76.4 28.5 8.4 6.8 10.0 3.6 11.0 0.4 2.1 12.5 19.1 19.0 9.3 1.1 1.3 0.5 7.9 0.2 3.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 127.9 131.0 122.0 147.7 166.8 120.6 154.9 130.9 142.6 124.6 139.3 164.4 1.7 6.4 4.1 7.2 0.9 2.4 5.8 2.0 2.8 34.4 6.1 5.3 1.1 5.7 3.3 11.0 22.9 1.6 0.4 2.2 13.7 6.9 43.8 23.9 15.9 2.9 40.2 0.0 10.3 28.9 0.6 6.5 4.1 19.9 0.0 2.8 0.4 4.6 0.5 67.3 11.6 1.6 4.1 0.8 3.5 39.2 6.2 1.1 3.6 1.0 1.6 41.3 0.0 3.5 48.7 11.6 0.5 6.4 0.1 6.3 1.4 8.9 10.9 18.3 0.0 14.2 6.0 10.6 8.2 0.9 1.0 5.7 1.3 7.7 0.9 5.5 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 37.7;pituitary gland: 23.3;retina: 15.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.7;Cone photoreceptor cells: 43.8;Excitatory neurons: 64.7;Inhibitory neurons: 70.3;Oligodendrocyte precursor cells: 22.1;Rod photoreceptor cells: 20.4" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Region enhanced" "Detected in many" "cerebral cortex: 37.7" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "AN3-CA: 23.3;SCLC-21H: 40.5;SH-SY5Y: 20.2;U-266/70: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 0.0 2.2 6.5 0.3 12.1 0.3 0.1 7.3 37.7 0.2 0.0 1.2 0.3 0.0 0.0 0.2 0.1 0.2 0.2 8.3 2.4 0.1 0.6 0.1 0.1 11.2 1.1 0.3 0.6 0.5 23.3 0.0 9.5 0.2 0.1 15.4 0.2 0.0 0.0 3.7 0.4 0.0 0.0 0.1 0.6 5.0 1.2 0.8 0.1 0.0 0.0 0.2 0.3 3.0 3.6 1.6 1.5 23.3 0.0 0.0 1.9 0.2 0.1 0.3 0.9 0.8 1.5 5.8 2.6 0.0 3.9 0.1 6.8 0.1 0.1 4.1 4.5 0.5 5.8 2.6 0.0 1.3 1.2 0.5 0.1 0.8 0.7 1.3 0.0 15.2 5.2 3.0 0.0 0.8 2.4 0.6 6.9 0.6 7.2 15.9 4.6 8.3 0.3 0.2 40.5 20.2 0.8 1.4 4.3 1.2 3.8 2.1 0.0 2.8 4.2 3.1 0.8 16.7 14.5 3.7 5.1 3.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 6.5 12.1 7.3 37.7 8.3 2.4 11.2 1.1 9.5 0.0 1.2 3.0 0.5 0.0 2.4 7.8 0.2 0.9 1.6 0.6 0.6 24.7 0.8 2.5 1.0 0.0 0.3 0.0 43.8 0.6 0.4 0.6 0.0 0.4 14.0 0.2 0.2 1.3 0.0 0.0 64.7 0.5 0.6 1.3 0.0 0.3 1.3 0.5 1.1 0.5 0.2 15.2 70.3 0.1 0.0 1.0 1.2 8.2 0.6 0.7 5.4 6.5 0.1 3.7 0.0 22.1 3.0 0.3 2.5 1.2 0.0 1.0 0.9 0.2 1.0 20.4 0.0 2.0 0.5 8.0 5.2 0.7 1.4 0.3 1.0 0.4 0.7 1.2 MLLT11 AF1Q ENSG00000213190 "MLLT11 transcription factor 7 cofactor" Q13015 1 151060397-151069544 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 54.1;Early spermatids: 76.9;Excitatory neurons: 57.9;Late spermatids: 215.6" "Cancer enriched" "Detected in all" 4 "glioma: 29.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 216.7;EFO-21: 164.9;SH-SY5Y: 238.6;U-698: 207.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000540 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA000540: AB_2666024" "unprognostic (2.96e-2)" "unprognostic (1.98e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (1.69e-1)" "unprognostic (1.96e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.49e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.25e-12)" "unprognostic (5.66e-3)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (3.94e-3)" 5.3 19.0 59.4 4.7 61.8 2.0 2.5 41.1 109.3 4.5 8.8 7.2 1.6 10.7 1.3 4.0 6.2 6.0 38.1 66.2 80.6 3.8 2.0 3.8 2.1 63.1 50.5 8.2 3.1 16.2 10.4 1.0 66.1 4.3 3.6 35.6 3.8 1.5 11.3 2.6 4.9 13.8 29.9 4.6 5.1 2.8 49.7 20.6 3.8 10.8 2.1 4.0 3.9 57.1 6.3 31.0 216.7 34.4 3.5 5.8 1.4 11.6 15.2 13.2 24.0 3.0 12.6 10.0 164.9 10.6 35.9 4.5 54.3 13.0 7.6 65.8 14.5 28.9 17.7 0.9 6.9 0.8 1.0 9.9 1.6 73.5 2.9 42.2 100.1 43.3 30.8 2.3 43.6 1.4 106.4 19.0 95.7 0.6 4.4 99.8 28.1 0.6 25.5 1.7 132.8 238.6 0.8 1.3 6.9 142.5 5.3 2.7 65.9 27.0 29.0 9.2 24.7 2.4 3.2 207.1 70.0 0.6 51.7 1.1 0.3 1.4 5.9 0.6 2.7 2.5 3.9 6.2 0.7 1.9 5.3 9.1 1.6 4.0 0.9 1.4 4.1 3.2 59.4 61.8 41.1 109.3 66.2 80.6 63.1 50.5 66.1 29.9 49.7 57.1 1.4 0.0 1.1 11.8 4.2 3.6 5.0 14.6 4.6 54.1 2.5 4.8 10.2 1.5 2.2 3.7 8.4 2.9 15.3 0.1 17.6 3.9 76.9 0.8 11.3 5.2 10.7 6.3 57.9 1.2 2.5 17.5 2.0 0.9 4.5 4.3 4.2 0.4 6.0 37.0 40.6 0.1 16.2 6.6 14.5 215.6 2.1 12.3 5.4 10.3 33.3 20.6 19.6 16.1 14.4 3.0 0.2 3.8 4.8 1.3 0.2 2.4 0.6 26.3 0.0 3.4 30.0 8.6 12.3 2.8 3.4 7.4 9.9 3.0 0.2 4.3 NCDN "NCDN-1, NCDN-2" ENSG00000020129 Neurochondrin Q9UBB6 1 35557473-35567274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 424.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.7;Inhibitory neurons: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023676 Enhanced Supported Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA023676: AB_1854325" "unprognostic (1.15e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (4.66e-2)" "unprognostic (1.41e-1)" "unprognostic (4.36e-2)" "prognostic favorable (3.73e-4)" "unprognostic (5.91e-3)" "unprognostic (5.34e-3)" "unprognostic (5.88e-3)" "unprognostic (2.87e-1)" "unprognostic (3.24e-2)" "unprognostic (2.23e-2)" 10.7 23.9 197.0 9.4 424.1 4.9 9.8 51.0 360.4 20.5 0.0 16.9 5.3 17.1 6.5 12.1 16.1 9.7 23.1 364.2 118.3 13.4 10.3 11.8 9.6 114.1 115.9 18.9 10.0 10.6 38.7 6.7 112.0 17.2 3.4 21.3 11.0 11.3 14.6 10.1 10.6 9.6 168.3 11.4 14.9 15.3 215.9 7.4 16.6 9.0 6.6 16.2 15.9 191.3 17.3 20.5 16.8 26.6 23.8 29.4 11.6 22.3 22.9 23.0 18.3 20.6 24.8 19.6 21.1 20.7 16.5 26.0 16.6 27.1 8.4 19.2 34.3 24.4 32.2 10.7 33.0 22.3 26.9 28.2 22.2 40.7 16.3 18.9 12.3 11.6 26.9 30.4 18.9 31.0 20.5 14.2 75.7 19.1 35.6 16.6 9.4 25.4 15.6 19.0 20.9 30.0 25.4 23.2 32.1 13.3 22.2 14.4 17.0 29.1 20.9 21.5 30.9 42.4 32.6 14.7 36.3 35.1 27.1 0.0 2.6 0.4 1.6 1.5 2.0 3.7 2.5 2.5 1.5 1.4 3.3 2.9 0.3 1.8 2.6 0.9 1.5 3.8 197.0 424.1 51.0 360.4 364.2 118.3 114.1 115.9 112.0 168.3 215.9 191.3 3.8 3.2 12.0 15.7 1.9 3.4 0.5 4.0 1.8 4.7 5.8 7.1 13.8 2.8 12.6 7.3 0.0 5.6 2.0 2.9 1.9 3.7 2.5 3.9 8.1 4.4 3.6 2.1 39.7 4.4 2.6 6.1 8.6 5.1 3.8 6.5 3.3 4.3 3.5 6.7 35.0 3.5 6.1 6.7 1.0 1.4 6.5 2.6 5.4 12.2 1.7 2.1 2.1 9.5 16.4 3.8 2.1 4.1 6.5 0.6 0.8 4.7 14.7 2.9 0.0 1.7 5.4 5.1 2.2 2.7 3.0 5.6 4.9 8.0 1.7 0.6 NGB ENSG00000165553 Neuroglobin Q9NPG2 14 77265483-77271312 "Predicted intracellular proteins, Transporters" "Apoptosis, Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 57.9;pituitary gland: 16.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.0;Excitatory neurons: 1.6;Inhibitory neurons: 1.7;Oligodendrocyte precursor cells: 3.5;Spermatogonia: 1.8" "Cancer enhanced" "Detected in some" "cervical cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 29 "RPMI-8226: 6.1;SCLC-21H: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042615, HPA058596" Enhanced NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042615: AB_2678079, HPA058596: AB_2683769" "unprognostic (1.02e-1)" "unprognostic (3.55e-2)" "unprognostic (8.86e-2)" "unprognostic (1.03e-1)" "unprognostic (9.29e-2)" "unprognostic (3.14e-1)" "unprognostic (4.08e-2)" "unprognostic (6.65e-2)" "unprognostic (6.58e-2)" "unprognostic (3.37e-4)" "unprognostic (1.80e-1)" "unprognostic (3.12e-1)" 0.1 7.5 20.6 0.2 17.2 0.0 0.0 11.8 26.8 0.0 10.7 5.5 0.2 0.0 0.1 0.1 1.3 0.0 0.0 15.2 57.9 0.0 0.0 0.0 0.0 24.8 29.0 0.0 5.0 0.0 16.9 0.0 29.9 0.0 0.5 0.5 0.0 0.0 0.0 0.0 1.0 0.1 15.5 0.0 1.0 0.5 40.9 0.2 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.1 0.0 0.0 12.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 17.2 11.8 26.8 15.2 57.9 24.8 29.0 29.9 15.5 40.9 15.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 1.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;kidney: 4.1;ovary: 8.1" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 156.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.7;midbrain: 7.6;pons: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.4;SiHa: 3.0;SuSa: 2.1;U-2 OS: 4.7;U-251 MG: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" NA Yes "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" 0.2 0.0 1.8 0.1 1.7 0.0 0.1 1.0 1.8 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.0 0.4 4.1 0.0 0.0 0.0 11.7 7.6 8.1 0.0 0.0 0.1 0.1 13.1 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.6 3.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 4.7 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.0 1.8 1.0 0.4 11.7 7.6 13.1 1.9 1.1 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 156.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR2L13 OR2L14 ENSG00000196071 "Olfactory receptor family 2 subfamily L member 13" Q8N349 1 248095184-248101103 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 6.7;retina: 2.2" "Group enriched" "Detected in some" 19 "Excitatory neurons: 140.4;Inhibitory neurons: 106.7;Oligodendrocyte precursor cells: 68.3;Oligodendrocytes: 139.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.39e-2)" "unprognostic (1.53e-1)" "unprognostic (9.89e-2)" "unprognostic (3.66e-1)" "unprognostic (7.01e-2)" "unprognostic (2.44e-2)" "unprognostic (1.14e-1)" 0.0 0.6 2.1 0.0 2.9 0.0 0.2 2.7 6.7 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 2.0 2.8 0.0 0.0 0.0 0.1 3.9 2.7 0.0 0.0 0.0 0.6 0.0 4.1 0.5 0.0 2.2 0.0 0.2 0.0 0.0 0.0 0.0 2.8 0.4 0.0 0.7 2.7 0.0 0.3 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.9 2.7 6.7 2.0 2.8 3.9 2.7 4.1 2.8 2.7 5.2 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 140.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.8 0.0 68.3 139.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 P2RX3 P2X3 ENSG00000109991 "Purinergic receptor P2X 3" P56373 11 57338352-57372396 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2.9;liver: 1.7;testis: 5.2" "Group enriched" "Detected in some" 28 "Early spermatids: 34.5;Late spermatids: 16.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA057776 Uncertain NA NA "Cluster 43: Testis - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA057776: AB_2683526" "unprognostic (5.44e-2)" "unprognostic (9.43e-2)" "unprognostic (2.84e-1)" "unprognostic (1.33e-3)" "unprognostic (2.24e-2)" "unprognostic (3.19e-3)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (3.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.49e-7)" "unprognostic (1.58e-1)" "unprognostic (2.88e-1)" "unprognostic (3.00e-2)" "unprognostic (1.29e-1)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 2.9 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.0 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.5 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PABPC1L2A RBM32A ENSG00000186288 "Poly(A) binding protein cytoplasmic 1 like 2A" Q5JQF8 X 73077276-73079512 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;prostate: 2.5" "Group enriched" "Detected in some" 10 "Early spermatids: 14.3;Late spermatids: 48.5" "Cancer enriched" "Detected in single" 15 "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.5" HPA041573 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 31: Spermatids - Spermatogenesis" "HPA041573: AB_2677556" "unprognostic (4.30e-2)" "unprognostic (2.19e-1)" "unprognostic (3.22e-1)" 0.0 1.0 4.6 0.0 3.9 0.0 0.0 2.3 6.3 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 3.7 6.1 0.0 0.0 0.0 0.0 2.6 2.7 0.0 0.0 0.1 2.0 0.0 2.5 2.5 0.0 1.1 1.8 0.2 0.0 0.0 0.1 0.0 0.8 0.2 0.0 1.7 4.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.9 2.3 6.3 3.7 6.1 2.6 2.7 2.5 0.8 4.3 3.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 48.5 0.3 0.0 0.0 0.0 0.0 0.5 0.0 3.0 1.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PABPC1L2B RBM32B ENSG00000184388 "Poly(A) binding protein cytoplasmic 1 like 2B" Q5JQF8 X 73002939-73006106 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.2;pituitary gland: 2.1;prostate: 2.7;salivary gland: 2.1;testis: 1.6" "Cell type enhanced" "Detected in some" "Early spermatids: 1.7;Excitatory neurons: 2.2;Inhibitory neurons: 2.7;Oligodendrocytes: 1.7" "Cancer enriched" "Detected in single" 23 "prostate cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" HPA041573 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA041573: AB_2677556" "unprognostic (1.73e-1)" "unprognostic (2.26e-1)" "unprognostic (3.31e-1)" 0.0 0.6 2.6 0.0 1.7 0.0 0.0 0.2 5.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.3 3.4 0.0 0.0 0.0 0.0 1.6 1.0 0.0 0.0 0.0 2.1 0.0 0.8 2.7 0.0 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 0.2 5.2 1.3 3.4 1.6 1.0 0.8 0.1 2.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537370-9839076 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 12.0;retina: 4.7" "Group enriched" "Detected in some" 4 "Breast myoepithelial cells: 6.5;Glandular and luminal cells: 2.0;Granulosa cells: 5.8" "Cancer enhanced" "Detected in single" "glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 4.6;SH-SY5Y: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020444 Approved Approved Nucleoplasm NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA020444: AB_1854947" "unprognostic (5.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (8.63e-2)" "unprognostic (3.21e-1)" "unprognostic (3.04e-1)" "unprognostic (2.25e-4)" "unprognostic (3.76e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (6.04e-2)" "unprognostic (4.58e-1)" 0.0 1.9 3.6 0.0 4.8 0.0 0.4 12.0 8.4 0.1 0.0 0.0 0.0 0.2 0.6 0.2 0.0 1.2 0.0 5.5 0.7 0.2 0.7 0.0 0.0 0.3 1.4 0.0 1.3 0.0 1.2 0.0 0.4 0.4 0.0 4.7 0.3 0.4 0.0 0.4 0.0 0.0 0.2 0.0 0.3 0.2 2.1 0.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.8 12.0 8.4 5.5 0.7 0.3 1.4 0.4 0.2 2.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845601 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 56.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 140.7;Extravillous trophoblasts: 71.9;Muller glia cells: 41.4;Oligodendrocytes: 37.6;Syncytiotrophoblasts: 74.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-87 MG: 19.8" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 5.6" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" NA NA 2000000 "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Endoplasmic reticulum, Vesicles" "HPA018412: AB_1854962, HPA018430: AB_1854961" "unprognostic (2.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.39e-2)" "unprognostic (2.85e-2)" "unprognostic (1.52e-4)" "unprognostic (1.85e-1)" "unprognostic (8.18e-4)" "unprognostic (4.35e-2)" 0.6 0.0 0.5 0.3 0.3 0.0 2.5 0.3 0.4 6.6 0.0 0.6 0.0 0.6 0.3 0.0 0.2 1.8 0.3 0.5 0.2 6.3 0.6 0.1 0.0 0.5 0.5 0.0 2.5 0.0 1.1 56.8 0.6 0.2 0.5 3.7 0.1 0.6 0.0 0.1 0.2 0.5 0.4 0.0 1.6 0.4 0.3 0.0 0.5 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 4.3 2.1 3.5 0.9 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.7 0.5 0.5 0.2 0.0 0.0 0.1 0.7 0.0 0.0 0.3 1.6 1.3 0.1 0.6 0.3 0.4 0.0 19.8 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.4 0.5 0.2 0.5 0.5 0.6 0.4 0.3 0.4 0.0 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.1 0.8 0.0 0.0 5.5 0.0 1.5 0.0 0.1 11.7 0.0 2.6 0.2 0.1 0.3 140.7 0.0 16.3 0.2 71.9 0.8 0.0 0.0 0.0 0.0 0.0 0.6 1.3 0.0 10.8 0.2 0.0 0.0 0.0 1.9 11.5 0.0 0.0 2.8 0.0 41.4 0.0 5.0 37.6 0.8 0.0 10.9 0.0 0.0 0.0 0.5 0.0 2.4 6.6 0.0 1.2 1.3 2.2 0.0 0.0 74.0 0.0 0.0 0.2 0.1 PCDHAC1 ENSG00000248383 "Protocadherin alpha subfamily C, 1" Q9H158 5 140926299-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "parathyroid gland: 29.8" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 1: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.7;EFO-21: 2.5;hTCEpi: 5.9;PC-3: 4.2;SCLC-21H: 2.9" "Low region specificity" "Detected in all" HPA052775 Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" Vesicles "HPA052775: AB_2681942" "unprognostic (2.52e-1)" "unprognostic (1.06e-1)" "unprognostic (3.32e-3)" "unprognostic (9.52e-3)" "unprognostic (1.36e-1)" "unprognostic (9.63e-2)" "unprognostic (4.27e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "unprognostic (6.24e-2)" "unprognostic (2.09e-1)" "unprognostic (3.64e-3)" "unprognostic (1.04e-3)" "unprognostic (3.25e-3)" "unprognostic (1.35e-1)" "unprognostic (2.96e-1)" "unprognostic (3.29e-2)" 0.4 0.4 0.6 0.5 0.7 0.0 0.1 4.5 1.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.0 0.0 0.5 0.5 0.2 0.1 0.7 1.2 2.0 3.1 0.0 1.2 29.8 0.7 0.0 2.3 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.7 0.7 0.0 0.9 0.0 0.6 0.0 0.0 0.6 0.0 5.7 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.7 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 4.2 0.0 0.0 0.0 0.1 0.3 2.9 1.7 0.0 0.4 0.0 0.5 0.3 0.0 0.0 0.3 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 4.5 1.0 0.5 0.5 2.0 3.1 2.3 0.0 0.7 0.6 0.1 6.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 1.2 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754012-83162930 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 25.6;pituitary gland: 11.1;retina: 21.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 655.4;Inhibitory neurons: 746.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 25.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 28 "REH: 263.3;U-2 OS: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" NA NA 6000000 "Cluster 58: Brain - Synaptic function" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles, Plasma membrane" "CAB079012: , HPA015858: AB_1855071, HPA029579: AB_10602044" "unprognostic (1.32e-2)" "unprognostic (1.99e-1)" "unprognostic (9.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.49e-3)" "unprognostic (6.14e-2)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-6)" "unprognostic (5.15e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-5)" "unprognostic (6.62e-5)" 1.8 4.2 4.0 0.2 5.5 0.0 2.4 25.6 22.4 1.5 0.0 2.1 1.5 0.3 3.8 2.3 1.0 0.9 1.4 7.8 1.7 4.4 0.1 0.8 0.1 0.0 0.0 0.8 3.9 4.4 11.1 0.3 0.0 2.5 1.7 21.7 2.5 2.5 0.1 2.0 1.7 0.1 0.0 0.5 1.5 3.7 1.3 1.2 4.6 0.1 0.2 0.6 2.6 4.2 1.2 1.6 1.9 0.0 0.8 0.1 0.0 0.7 0.7 0.5 1.0 0.3 0.7 0.0 0.0 0.8 7.7 0.6 5.7 2.4 2.4 0.3 0.8 0.0 1.2 0.1 0.0 0.8 0.2 0.4 1.8 0.0 9.6 0.5 0.0 0.1 0.0 0.0 0.8 0.8 0.2 0.0 2.0 1.0 4.7 263.3 4.2 0.0 1.9 0.9 4.9 3.4 0.2 2.7 0.6 1.2 3.4 0.6 0.0 0.0 284.5 1.2 0.6 0.2 0.0 0.5 1.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.5 25.6 22.4 7.8 1.7 0.0 0.0 0.0 0.0 1.3 4.2 0.6 9.6 17.9 40.5 0.0 2.5 9.0 3.2 13.6 121.9 11.0 9.7 31.2 22.8 12.6 1.8 131.3 1.9 0.0 22.9 7.9 6.4 13.0 7.4 6.7 2.5 60.1 0.0 655.4 4.9 0.4 2.4 20.4 13.5 0.0 24.2 0.0 0.2 1.7 85.8 746.4 15.0 2.0 0.0 0.0 7.9 2.8 0.4 0.0 50.6 0.0 16.2 0.0 73.9 73.7 2.5 21.9 6.4 0.0 3.9 13.5 23.0 7.7 86.9 0.0 0.3 3.2 5.0 19.5 19.3 3.4 0.7 0.3 37.5 9.3 6.0 PCSK1 "NEC1, PC1, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390333-96434143 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 68.3" "Cell type enriched" "Detected in some" 4 "Enteroendocrine cells: 224.6" "Cancer enhanced" "Detected in many" "breast cancer: 12.1" "Group enriched" "Detected in all" 5 "cerebral cortex: 19.1;hypothalamus: 68.3;pons: 30.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 22.6;U-138 MG: 19.0;U-87 MG: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048564, HPA079656" Approved "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA048564: AB_2680444, HPA079656: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavorable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" 1.7 6.3 5.5 4.7 3.7 0.1 1.4 1.0 19.1 0.9 0.0 2.4 5.2 0.1 0.0 0.1 0.2 0.2 0.8 3.0 68.3 0.4 0.0 0.3 0.1 6.6 7.7 0.4 7.6 0.0 12.1 0.0 30.0 0.4 2.3 8.7 2.7 0.1 0.3 1.1 3.6 0.6 4.0 0.1 5.7 0.1 6.6 0.2 1.9 0.0 0.0 2.0 0.5 5.3 0.0 0.0 0.3 0.0 2.3 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 1.0 3.8 0.0 0.0 0.1 0.0 0.1 0.1 0.8 2.4 0.0 0.0 0.0 0.0 2.0 1.0 0.4 0.1 0.2 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 3.3 0.0 0.0 0.4 0.0 0.0 1.2 19.0 0.6 0.3 0.2 0.0 0.0 0.1 15.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 3.7 1.0 19.1 3.0 68.3 6.6 7.7 30.0 4.0 6.6 5.3 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 1.8 13.2 0.0 0.0 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.2 0.2 224.6 0.0 54.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 4.0 10.7 2.0 0.0 0.4 1.6 0.0 0.0 0.0 4.7 0.0 0.5 0.0 3.5 4.9 1.5 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.9 0.0 1.7 1.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.7 0.0 PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 642.6;pituitary gland: 1243.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 3045.7;Horizontal cells: 437.4;Paneth cells: 628.8;Proximal tubular cells: 1601.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "HEK 293: 58.9;PC-3: 148.5;SCLC-21H: 58.2;SH-SY5Y: 53.8;SiHa: 52.1;U-266/84: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" NA NA 3300000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favorable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" 2.2 29.5 177.1 0.5 135.6 0.0 2.0 21.6 212.8 18.2 118.8 19.2 9.6 34.1 2.9 0.9 6.9 0.2 16.0 105.6 642.6 152.1 1.3 2.9 0.1 290.3 257.1 2.3 54.0 11.1 1243.7 0.2 193.0 14.4 0.5 2.5 6.7 0.8 0.8 8.8 13.7 0.6 95.5 1.1 21.9 19.7 264.9 0.0 3.3 0.0 0.0 1.2 6.5 51.8 0.1 5.4 0.2 14.9 0.6 0.0 0.4 0.0 0.0 0.0 0.0 5.3 0.1 0.0 10.4 0.0 4.2 0.8 0.0 1.1 0.0 0.0 58.9 0.0 0.0 9.3 0.0 0.0 3.7 0.0 0.8 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.0 7.6 0.0 0.5 7.9 0.0 148.5 0.0 0.0 0.4 1.4 0.2 58.2 53.8 52.1 0.2 4.9 0.7 0.2 0.1 0.1 0.1 22.7 0.2 5.0 13.3 73.6 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.8 0.0 2.4 0.0 5.0 4.9 0.0 0.0 2.0 6.4 0.0 0.0 0.0 0.0 1.8 0.7 177.1 135.6 21.6 212.8 105.6 642.6 290.3 257.1 193.0 95.5 264.9 51.8 0.8 0.0 0.0 29.0 12.5 15.8 1.3 4.3 0.6 139.6 11.4 14.9 1.4 2.8 4.3 389.9 52.1 1.0 1.0 18.2 277.8 8.6 12.8 44.3 8.7 3.6 3045.7 2.7 64.8 0.7 69.0 17.2 112.1 35.2 0.0 2.5 0.0 0.5 1.7 437.4 118.8 218.9 54.9 0.3 17.2 52.9 3.4 10.5 56.9 22.5 0.4 96.2 1.0 72.9 26.0 23.1 628.8 7.2 4.5 30.4 21.6 1601.1 24.8 148.2 0.0 0.3 12.6 32.5 82.2 0.2 11.5 1.9 20.1 0.2 15.6 3.7 PGRMC1 HPR6.6 ENSG00000101856 "Progesterone receptor membrane component 1" O00264 X 119236245-119244466 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 677.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 520.4;Theca cells: 907.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002877, HPA064724" Enhanced Supported "Nucleoli,Endoplasmic reticulum" NA NA 1200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" Nucleoli "HPA002877: AB_1079602, HPA064724: " "unprognostic (6.97e-2)" "unprognostic (1.99e-1)" "unprognostic (1.72e-1)" "unprognostic (4.35e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.58e-3)" "unprognostic (9.28e-2)" "unprognostic (4.66e-2)" "unprognostic (6.20e-2)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-3)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 108.0 171.3 97.9 37.5 102.5 25.1 106.0 83.8 115.5 135.4 96.3 98.2 109.3 154.5 273.3 57.0 149.0 56.9 38.6 102.3 127.0 235.4 677.4 62.1 27.6 97.2 109.3 93.3 40.2 113.9 59.1 44.9 126.1 127.6 87.3 80.5 71.4 200.4 15.7 53.2 131.9 85.2 106.1 41.4 77.1 46.5 112.8 33.4 89.0 27.0 29.3 77.3 65.0 116.9 165.6 102.4 196.3 227.7 414.2 196.9 127.1 243.0 281.0 126.1 155.7 124.5 196.6 47.3 259.5 253.8 147.3 128.3 216.5 102.1 168.8 50.8 248.7 53.7 88.5 141.0 69.0 88.4 27.5 204.7 56.5 153.8 79.2 93.5 82.6 55.7 57.2 28.8 150.3 176.5 66.9 64.7 515.8 179.4 170.3 78.5 123.1 68.5 168.7 123.9 182.9 81.7 178.1 291.7 98.9 188.2 67.4 56.2 64.2 87.6 127.7 312.6 233.6 29.9 59.2 51.0 238.8 138.6 170.6 21.0 20.1 20.4 8.7 19.9 11.8 5.8 12.0 12.9 17.0 5.5 12.0 10.1 9.1 8.8 18.4 12.0 13.4 50.2 97.9 102.5 83.8 115.5 102.3 127.0 97.2 109.3 126.1 106.1 112.8 116.9 109.1 125.0 91.4 16.0 19.0 94.1 131.3 67.4 81.4 199.1 110.8 95.1 17.1 120.1 76.7 73.5 68.8 88.2 25.8 170.5 68.4 93.0 4.2 119.7 264.2 81.9 57.7 37.6 36.5 73.0 138.6 153.1 50.4 122.4 40.5 197.0 66.4 520.4 51.8 65.6 58.5 85.0 81.4 35.0 51.2 9.0 172.1 111.1 103.2 15.0 26.5 109.8 18.6 108.6 91.3 68.9 144.7 181.7 22.6 118.8 375.5 295.1 105.4 92.4 105.2 99.2 111.1 68.2 77.2 69.3 87.7 62.1 32.1 907.9 137.6 127.9 PNMA2 "MA2, RGAG2" ENSG00000240694 "PNMA family member 2" Q9UL42 8 26504701-26514092 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;retina: 24.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 71.2;Horizontal cells: 30.3;Inhibitory neurons: 92.0;Muller glia cells: 26.9" "Cancer enhanced" "Detected in many" "glioma: 28.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 63.0;hTERT-RPE1: 78.4;JURKAT: 43.3;SH-SY5Y: 44.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001936 Enhanced NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA001936: AB_1079647" "unprognostic (1.25e-2)" "unprognostic (1.27e-2)" "unprognostic (6.39e-2)" "unprognostic (1.43e-6)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" "unprognostic (8.76e-2)" "prognostic favorable (1.81e-4)" "unprognostic (4.66e-2)" "unprognostic (1.34e-2)" "unprognostic (1.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.98e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.12e-2)" "unprognostic (4.58e-5)" "unprognostic (9.00e-3)" 2.6 10.8 52.2 1.2 55.1 0.4 1.9 1.3 73.4 3.5 0.0 1.4 0.8 0.8 1.0 0.5 2.5 3.9 4.9 55.1 88.4 3.2 0.9 6.8 0.4 29.0 25.7 0.8 3.9 2.7 15.4 0.5 28.7 0.8 0.9 24.5 0.3 0.9 0.5 0.6 1.1 1.9 16.5 0.5 2.8 1.7 67.0 0.2 2.7 0.2 0.3 2.2 0.8 29.2 0.0 11.7 63.0 0.6 12.2 2.6 0.1 3.2 17.2 7.8 2.6 0.5 8.4 0.0 2.3 1.2 19.3 0.2 39.5 0.0 6.0 0.0 7.0 0.0 8.7 0.1 0.9 0.0 0.4 4.2 0.0 33.4 0.2 78.4 37.7 43.3 0.0 0.1 4.9 0.3 19.3 0.1 34.7 0.7 0.1 0.1 12.8 0.0 18.7 4.3 30.7 44.9 0.0 0.1 2.1 4.5 0.2 1.2 18.6 0.8 12.7 16.1 2.6 5.9 4.6 0.1 36.1 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 52.2 55.1 1.3 73.4 55.1 88.4 29.0 25.7 28.7 16.5 67.0 29.2 0.4 3.2 13.0 20.5 0.6 0.0 0.1 0.2 0.0 6.5 0.9 1.1 0.5 0.0 3.7 0.0 2.1 0.0 0.0 0.1 0.0 0.3 5.4 1.0 4.5 1.0 10.8 0.0 71.2 0.0 0.1 3.6 0.0 1.5 1.3 0.0 0.4 0.1 0.1 30.3 92.0 0.5 0.0 1.6 0.8 1.5 11.1 0.1 1.8 12.2 0.0 26.9 0.0 19.1 11.5 2.7 0.0 12.0 0.0 0.0 0.0 5.4 2.9 6.2 0.0 0.2 4.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.2 0.2 PNMA8C ENSG00000277531 "PNMA family member 8C" A0A1B0GUJ8 19 46424697-46428951 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 15.9;pituitary gland: 8.6" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.3;Endometrial ciliated cells: 1.3" "Cancer enriched" "Detected in some" 11 "glioma: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 1.1;HMC-1: 2.4;SH-SY5Y: 3.7" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (3.25e-2)" "unprognostic (2.38e-1)" "unprognostic (3.89e-2)" "unprognostic (4.91e-3)" "unprognostic (2.58e-1)" "unprognostic (4.61e-3)" "unprognostic (1.16e-2)" "unprognostic (1.69e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-2)" "unprognostic (2.92e-2)" 0.0 1.1 12.3 0.1 13.0 0.1 0.2 1.6 11.4 0.0 1.5 0.2 0.0 0.1 2.0 0.0 1.2 0.2 0.1 11.0 15.1 0.0 0.0 0.1 0.0 5.9 10.2 0.1 0.0 0.1 8.6 0.0 7.1 0.3 0.0 2.0 0.0 0.4 0.7 0.1 0.1 0.1 5.9 0.0 0.0 0.6 15.9 0.0 0.0 0.0 0.0 0.1 0.0 8.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 12.3 13.0 1.6 11.4 11.0 15.1 5.9 10.2 7.1 5.9 15.9 8.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 PRMT8 "HRMT1L3, HRMT1L4" ENSG00000111218 "Protein arginine methyltransferase 8" Q9NR22 12 3381349-3593973 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.8;retina: 3.9;testis: 2.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 21.7;Cone photoreceptor cells: 16.7;Early spermatids: 22.8;Excitatory neurons: 60.5;Inhibitory neurons: 63.8;Late spermatids: 15.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "hTERT-HME1: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039747, HPA069769" Enhanced NA NA "Cluster 58: Brain - Synaptic function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA039747: AB_2732482, HPA069769: AB_2686193" "unprognostic (3.09e-1)" "unprognostic (9.47e-2)" "unprognostic (5.59e-1)" "unprognostic (3.34e-3)" "unprognostic (4.80e-3)" "unprognostic (9.41e-2)" "unprognostic (3.41e-5)" "unprognostic (5.99e-1)" "unprognostic (1.93e-1)" "unprognostic (1.50e-2)" "unprognostic (7.06e-2)" "unprognostic (2.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.64e-1)" "unprognostic (6.02e-2)" "unprognostic (5.49e-2)" 0.0 0.0 3.2 0.0 7.8 0.0 0.0 3.8 7.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.0 5.4 1.5 0.6 0.0 0.8 0.0 2.1 3.0 0.0 0.6 0.0 0.1 0.0 0.7 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.5 4.0 1.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 48.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 7.8 3.8 7.2 5.4 1.5 2.1 3.0 0.7 0.3 4.0 3.6 0.0 6.4 1.7 1.6 0.1 0.0 0.0 0.0 0.0 21.7 0.1 0.0 1.3 0.0 5.0 0.0 16.7 0.0 0.0 0.1 0.0 0.0 22.8 2.2 0.1 0.3 0.0 0.0 60.5 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 5.0 63.8 0.0 4.1 0.0 4.2 15.4 0.6 0.4 0.0 1.0 0.0 0.7 0.0 3.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 7.5 1.6 0.0 0.0 0.2 3.5 1.5 0.0 0.0 0.0 0.2 0.0 0.1 0.2 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase receptor type N2" Q92932 7 157539056-158587823 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;pancreas: 98.1" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 131.1;Excitatory neurons: 439.6;Inhibitory neurons: 433.4;Oligodendrocyte precursor cells: 138.2" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 23.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 23.6" "Cell line enhanced" "Detected in many" "AF22: 45.5;HDLM-2: 42.0;MOLT-4: 22.1;NB-4: 43.0;SCLC-21H: 23.8;SH-SY5Y: 25.4;U-87 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 3.8 16.5 29.4 2.7 34.3 1.3 2.9 0.0 49.9 2.1 0.0 7.7 8.3 3.0 4.2 1.9 10.8 7.6 3.1 35.2 22.7 3.9 1.6 4.8 3.4 7.9 3.1 8.7 98.1 1.0 41.0 2.1 3.4 17.3 6.1 9.2 12.9 3.6 1.2 0.8 6.7 2.1 0.1 13.4 40.2 6.2 14.1 1.6 8.7 1.9 2.5 4.2 2.1 20.5 0.1 0.4 45.5 3.6 0.1 0.2 0.1 0.4 0.3 0.0 0.1 0.0 4.0 0.0 1.2 0.5 9.4 0.3 1.0 0.0 0.0 42.0 0.8 0.0 0.0 7.3 1.1 0.0 0.1 2.0 0.8 0.1 0.5 0.3 0.0 3.4 0.1 0.3 0.0 0.7 22.1 43.0 5.7 13.7 3.2 0.0 2.7 0.2 0.2 0.0 23.8 25.4 0.0 0.1 0.0 0.0 0.0 20.9 6.2 9.2 4.3 0.1 1.5 0.3 0.1 0.0 27.7 17.4 6.8 14.1 1.5 2.8 1.3 0.2 0.5 3.5 2.1 1.4 2.1 4.2 2.4 1.4 23.6 2.4 0.0 0.6 5.3 1.3 29.4 34.3 0.0 49.9 35.2 22.7 7.9 3.1 3.4 0.1 14.1 20.5 40.7 3.2 12.9 16.3 18.4 2.3 12.7 1.3 4.0 30.2 1.9 2.2 3.1 10.0 9.1 40.5 10.4 0.4 8.7 5.9 35.2 22.9 51.9 8.7 2.5 26.3 131.1 6.6 439.6 13.1 0.4 13.0 41.8 0.8 19.0 14.1 44.3 0.8 44.5 11.8 433.4 43.3 6.1 7.0 11.3 19.3 12.5 7.9 12.4 27.2 5.7 67.3 15.5 138.2 11.0 7.3 7.0 19.5 5.4 15.0 6.5 3.8 52.6 8.0 26.3 1.4 7.0 62.8 16.3 4.8 1.4 0.7 14.8 32.7 9.7 24.8 RAB39B "MRX72, WSN" ENSG00000155961 "RAB39B, member RAS oncogene family" Q96DA2 X 155258235-155264491 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Autism spectrum disorder, Disease variant, Mental retardation, Parkinson disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.7;retina: 9.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.8;Horizontal cells: 10.1;Inhibitory neurons: 9.8;Muller glia cells: 11.6;Oligodendrocytes: 10.3" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 27.8;Karpas-707: 35.6;U-266/70: 35.5;U-266/84: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001114, HPA042505" Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA001114: AB_1079732, HPA042505: AB_2678030" "prognostic favorable (8.95e-4)" "unprognostic (1.20e-3)" "unprognostic (3.52e-2)" "unprognostic (7.10e-5)" "unprognostic (1.77e-1)" "unprognostic (7.47e-4)" "unprognostic (2.19e-1)" "unprognostic (6.00e-4)" "unprognostic (1.78e-1)" "unprognostic (5.64e-2)" "unprognostic (3.87e-4)" "unprognostic (5.41e-2)" "unprognostic (1.72e-1)" "unprognostic (7.21e-2)" "unprognostic (4.94e-2)" "unprognostic (6.35e-2)" "unprognostic (3.24e-1)" 0.2 1.9 6.5 2.8 6.7 0.9 0.7 6.8 10.7 0.4 3.0 0.7 0.6 0.3 6.4 0.3 0.5 0.6 0.3 7.0 7.0 0.7 0.3 0.6 5.3 6.4 6.1 0.4 2.5 3.8 6.5 0.2 6.9 1.9 0.6 9.9 0.4 1.3 0.0 0.0 1.2 0.2 6.1 3.1 1.3 0.9 7.0 5.3 2.4 0.0 5.9 0.8 0.1 8.2 0.0 0.4 5.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 27.8 1.2 0.1 14.9 0.0 0.0 0.2 0.1 11.8 0.5 2.3 0.0 0.0 1.7 0.0 4.8 0.1 0.0 0.4 7.8 0.9 0.0 10.3 0.0 35.6 0.1 2.1 10.3 0.0 6.9 0.0 0.6 0.0 0.0 2.3 0.0 0.0 13.4 10.3 0.0 0.0 6.4 1.8 0.4 0.2 0.0 0.7 2.2 0.0 1.1 35.5 26.7 6.2 6.2 0.0 0.0 0.8 0.3 2.2 4.6 0.2 4.7 4.2 6.0 6.0 4.6 2.8 6.1 6.9 2.7 3.3 0.4 1.1 4.8 3.2 6.5 6.7 6.8 10.7 7.0 7.0 6.4 6.1 6.9 6.1 7.0 8.2 0.9 0.0 0.0 2.6 7.9 0.5 0.5 0.0 0.0 11.8 0.6 0.9 2.4 0.0 0.0 1.8 8.4 0.0 7.6 0.0 0.0 0.2 0.2 0.0 0.7 0.8 1.8 3.0 7.7 0.9 0.0 0.7 1.1 0.1 0.0 2.6 1.8 0.0 0.1 10.1 9.8 0.0 0.0 0.3 3.1 0.0 0.0 1.5 3.6 1.0 2.2 11.6 6.2 8.0 10.3 0.4 0.0 1.9 9.2 0.6 0.0 0.9 0.0 8.0 0.0 0.1 2.4 0.4 0.8 0.0 0.1 0.0 9.1 8.2 0.0 0.0 RGS4 SCZD9 ENSG00000117152 "Regulator of G protein signaling 4" P49798 1 163068775-163076802 "Disease related genes, Predicted intracellular proteins" "Signal transduction inhibitor" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 34.6;brain: 120.6" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 51.6;Excitatory neurons: 115.4;Inhibitory neurons: 59.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 120.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "hTERT-RPE1: 527.4;LHCN-M2: 244.2;SH-SY5Y: 429.5;TIME: 959.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030802 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA030802: AB_10602295" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (3.02e-2)" "unprognostic (6.84e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.26e-2)" "unprognostic (1.27e-1)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (6.45e-2)" "unprognostic (2.12e-2)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.97e-4)" "prognostic unfavorable (1.92e-4)" "unprognostic (1.00e-1)" "unprognostic (8.33e-2)" "unprognostic (2.30e-2)" 8.2 34.6 35.6 3.0 46.7 0.0 1.7 0.0 120.6 5.9 0.0 4.3 4.2 7.8 1.2 9.7 7.3 18.3 8.7 49.3 42.2 1.9 4.0 3.0 3.7 0.0 5.2 2.2 4.7 2.3 14.3 1.6 2.0 4.7 2.5 6.7 0.8 6.5 0.4 0.3 2.8 4.7 0.0 1.7 8.4 3.0 0.0 1.8 3.1 1.4 0.4 5.9 1.4 39.7 0.3 0.0 1.2 7.2 25.1 115.9 0.2 77.8 92.1 12.6 31.9 0.0 0.3 0.3 35.6 50.2 0.5 0.2 0.0 0.1 42.2 0.4 0.1 0.3 0.0 0.0 11.0 0.2 0.2 19.0 0.0 123.0 14.3 527.4 127.5 0.0 0.1 0.6 244.2 0.0 0.0 0.5 6.5 0.0 9.6 0.1 0.0 0.4 0.0 0.0 2.9 429.5 0.0 0.1 0.2 4.0 0.1 0.1 959.6 91.5 5.2 19.1 129.5 0.1 0.1 0.3 11.4 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 46.7 0.0 120.6 49.3 42.2 0.0 5.2 2.0 0.0 0.0 39.7 0.8 0.0 0.0 15.7 0.0 0.3 1.7 0.1 0.0 4.3 0.7 0.0 0.7 0.0 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.3 12.6 0.5 16.9 2.6 51.6 0.0 115.4 0.2 0.1 20.2 0.0 0.4 0.0 1.1 1.1 0.0 0.4 0.0 59.9 0.0 0.0 0.0 0.5 3.8 0.0 0.1 0.0 13.1 0.0 15.7 0.0 13.0 13.0 2.7 0.1 0.0 0.0 0.5 0.0 0.0 0.7 1.6 0.0 0.2 17.0 0.1 0.6 0.5 0.3 0.1 0.6 0.1 0.1 0.3 RIMBP2 "KIAA0318, MGC15831, PPP1R133, RBP2, RIM-BP2" ENSG00000060709 "RIMS binding protein 2" O15034 12 130396137-130716281 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.9;parathyroid gland: 24.6;pituitary gland: 32.2" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 75.5;Excitatory neurons: 128.2;Inhibitory neurons: 191.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 28.9;SH-SY5Y: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041494, HPA044114" Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA041494: , HPA044114: AB_2678815" "unprognostic (4.15e-4)" "unprognostic (9.77e-3)" "unprognostic (1.20e-1)" "unprognostic (6.45e-2)" "unprognostic (1.91e-3)" "unprognostic (3.63e-1)" "unprognostic (1.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (6.82e-3)" "prognostic favorable (4.16e-4)" "unprognostic (2.86e-1)" "unprognostic (6.41e-3)" "unprognostic (5.27e-2)" "unprognostic (2.07e-1)" "unprognostic (1.03e-1)" "unprognostic (4.73e-2)" 0.6 14.5 6.3 0.9 11.3 0.2 0.2 0.0 17.5 7.2 17.3 1.5 2.9 2.7 2.5 0.5 7.8 0.9 0.0 25.9 19.2 5.9 0.2 0.4 0.1 1.7 19.6 2.1 2.5 24.6 32.2 0.0 20.6 1.1 1.8 11.2 0.3 1.3 0.2 2.7 2.5 2.4 0.1 1.0 5.9 2.6 0.9 0.3 0.6 3.9 0.1 0.3 0.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.0 0.4 7.3 0.0 0.0 28.9 55.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 11.3 0.0 17.5 25.9 19.2 1.7 19.6 20.6 0.1 0.9 2.7 0.4 0.0 0.0 5.9 0.0 2.0 0.1 0.0 0.6 19.4 0.0 0.1 1.4 0.0 0.0 0.0 31.3 0.0 0.0 0.4 0.0 0.0 3.8 3.0 1.4 0.4 75.5 0.0 128.2 0.0 0.0 0.7 4.1 6.4 0.0 0.0 0.0 0.0 0.0 10.1 191.4 2.6 6.1 0.0 0.5 2.1 0.9 0.0 0.0 1.0 0.0 3.2 0.0 19.6 5.3 0.1 0.1 0.7 0.0 0.1 0.0 0.1 0.7 14.0 0.0 0.0 0.2 1.7 1.5 0.1 0.6 0.0 0.1 0.0 0.8 0.0 RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500696-104256094 "Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 50.6;brain: 48.2;retina: 102.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 383.6;Cone photoreceptor cells: 706.8;Excitatory neurons: 1589.3;Inhibitory neurons: 1234.9;Oligodendrocyte precursor cells: 577.0;Rod photoreceptor cells: 1088.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 9.2;RT4: 7.3;SCLC-21H: 16.5;SuSa: 8.8;U-2 OS: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: AB_2685678" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" 0.2 50.6 22.4 0.2 27.1 0.4 0.7 35.5 48.2 7.5 0.0 0.1 0.4 0.6 0.9 0.3 5.9 0.9 0.1 18.4 16.4 0.3 0.1 0.1 0.3 5.5 9.7 2.0 0.7 0.0 15.0 0.4 6.4 1.7 0.1 102.3 0.8 1.0 0.2 0.3 0.5 1.3 3.5 0.1 0.6 2.8 16.7 0.8 1.3 0.1 0.2 1.7 2.4 29.4 4.6 0.0 4.8 0.0 0.0 0.1 0.0 0.4 0.3 1.0 1.3 0.1 0.3 9.2 0.1 0.1 1.4 0.3 1.9 0.8 2.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 1.0 1.5 0.0 1.2 0.0 0.5 0.0 0.4 0.9 0.0 4.0 0.0 0.5 0.0 0.0 0.0 0.0 7.3 16.5 3.3 0.0 0.1 0.7 8.8 0.4 0.2 0.0 0.0 6.5 0.1 0.1 1.2 0.0 0.1 0.4 0.3 0.3 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 22.4 27.1 35.5 48.2 18.4 16.4 5.5 9.7 6.4 3.5 16.7 29.4 0.4 28.9 22.5 38.5 0.2 0.3 1.8 2.8 1.8 383.6 0.7 0.6 0.9 1.5 16.9 0.0 706.8 0.5 0.1 0.2 1.9 0.1 34.2 2.1 0.4 4.9 8.4 0.0 1589.3 0.0 0.3 3.7 0.0 3.7 16.4 18.0 0.7 0.3 0.3 67.3 1234.9 0.9 0.0 0.6 0.8 20.1 72.1 2.5 1.8 63.7 0.6 86.6 1.0 577.0 27.0 0.3 1.2 29.3 0.3 4.1 2.0 0.2 10.6 1088.7 0.0 0.8 1.0 34.8 15.7 0.8 0.4 0.1 2.1 0.1 1.5 1.1 RNF175 FLJ34190 ENSG00000145428 "Ring finger protein 175" Q8N4F7 4 153710160-153760024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;choroid plexus: 10.8" "Group enriched" "Detected in some" 5 "Early spermatids: 72.8;Excitatory neurons: 91.4;Inhibitory neurons: 95.7;Oligodendrocyte precursor cells: 38.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 8.8;HSkMC: 5.8;REH: 6.7;SH-SY5Y: 7.6;THP-1: 17.5;U-87 MG: 4.5" HPA035837 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA035837: AB_10601609" "unprognostic (3.23e-2)" "unprognostic (4.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-4)" "unprognostic (1.17e-1)" "unprognostic (2.96e-3)" "unprognostic (6.30e-3)" "unprognostic (1.42e-1)" "unprognostic (3.63e-4)" "unprognostic (7.25e-3)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" 1.5 2.5 18.8 2.9 19.2 6.1 0.8 15.0 27.6 3.0 10.8 0.6 0.1 0.2 0.9 0.6 0.5 1.0 4.0 18.3 21.8 0.2 0.4 1.4 1.2 17.7 15.3 0.1 0.3 0.0 4.0 0.1 17.6 2.4 0.1 3.5 1.4 3.4 0.1 0.7 0.5 0.1 14.1 2.5 0.3 1.6 18.0 0.1 0.2 0.5 0.6 0.5 1.5 17.5 0.2 0.0 8.8 0.0 0.0 0.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 6.7 0.0 0.3 0.0 0.1 0.0 7.6 0.0 0.0 0.2 0.1 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.9 0.0 0.0 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.9 0.0 2.2 0.0 2.4 0.0 2.1 0.0 0.6 0.6 18.8 19.2 15.0 27.6 18.3 21.8 17.7 15.3 17.6 14.1 18.0 17.5 0.1 0.0 0.5 6.8 0.0 0.4 0.1 0.6 0.6 0.7 0.1 0.6 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.8 0.0 0.1 0.2 0.0 0.4 91.4 0.0 0.0 2.9 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 95.7 0.0 0.0 5.9 2.9 14.6 0.0 1.5 1.8 2.8 0.7 0.8 0.0 38.7 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 1.6 0.0 0.0 0.3 1.5 1.3 0.0 0.3 0.0 0.6 0.0 0.0 0.2 SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 24.7" "Group enriched" "Detected in some" 11 "Excitatory neurons: 409.9;Inhibitory neurons: 494.6;Oligodendrocyte precursor cells: 692.1" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 6.1;Hep G2: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: AB_2686888" "unprognostic (9.25e-2)" "unprognostic (3.97e-2)" "unprognostic (6.88e-2)" "unprognostic (7.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "unprognostic (4.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-1)" "unprognostic (9.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.03e-9)" "unprognostic (6.92e-2)" "unprognostic (3.69e-2)" "unprognostic (5.06e-3)" "unprognostic (6.93e-1)" 0.0 0.0 4.2 0.0 4.2 0.0 0.0 2.1 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.1 6.9 0.0 0.0 1.4 0.0 14.2 6.2 0.0 0.0 0.0 2.0 0.0 18.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.9 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.2 2.1 24.7 2.1 6.9 14.2 6.2 18.5 2.2 10.9 10.9 0.0 6.4 33.9 27.4 0.0 0.0 0.0 0.0 0.0 47.4 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.5 0.0 0.3 1.8 0.0 409.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 494.6 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 18.7 0.0 2.8 0.0 692.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SCN2A "HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2" ENSG00000136531 "Sodium voltage-gated channel alpha subunit 2" Q99250 2 165194993-165392310 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 26.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 440.4;Inhibitory neurons: 364.7;Oligodendrocyte precursor cells: 246.3" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 2.1;U-138 MG: 3.4;U-266/84: 8.1;U-87 MG: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022567 Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB022567: " "unprognostic (1.16e-1)" "unprognostic (3.56e-4)" "unprognostic (5.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.97e-1)" "unprognostic (8.62e-3)" "unprognostic (1.18e-1)" "unprognostic (7.25e-3)" "unprognostic (1.40e-1)" "unprognostic (2.78e-1)" "unprognostic (1.32e-2)" "unprognostic (5.21e-2)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-1)" "unprognostic (4.88e-2)" "unprognostic (2.14e-1)" 0.2 1.3 15.8 0.1 17.5 0.0 0.7 26.1 20.1 0.2 0.0 0.1 0.2 0.5 0.9 0.0 0.1 0.8 0.1 22.2 8.0 3.5 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 3.7 0.1 0.0 0.1 0.1 4.6 0.2 0.4 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.3 2.5 0.3 0.0 0.0 0.0 0.1 0.3 5.8 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.4 0.0 0.2 0.0 0.3 0.0 0.1 2.1 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.2 0.9 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.2 0.2 0.0 0.3 8.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 17.5 26.1 20.1 22.2 8.0 0.0 0.0 0.0 0.0 2.5 5.8 0.1 0.0 1.7 18.3 0.5 0.3 0.1 0.2 0.0 49.8 0.3 4.7 0.8 0.0 0.0 11.0 47.9 0.1 0.2 0.0 5.9 0.2 1.6 0.1 2.3 0.3 0.0 0.0 440.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.2 364.7 0.0 0.0 0.0 0.0 1.4 1.2 0.0 0.0 60.9 0.0 3.4 0.0 246.3 17.0 0.3 0.0 6.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.0 0.6 0.0 0.9 0.1 0.1 0.0 0.4 1.0 0.0 0.0 SEZ6L2 "FLJ90517, PSK-1" ENSG00000174938 "Seizure related 6 homolog like 2" Q6UXD5 16 29871159-29899547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.6;pituitary gland: 91.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 236.6;Cone photoreceptor cells: 185.6;Enteroendocrine cells: 132.5;Horizontal cells: 188.4;Rod photoreceptor cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064471 Enhanced NA NA 5600000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA064471: AB_2685271" "unprognostic (2.56e-2)" "prognostic unfavorable (7.46e-4)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.27e-1)" "unprognostic (1.67e-2)" "unprognostic (2.71e-2)" "unprognostic (8.22e-2)" "unprognostic (1.85e-1)" "unprognostic (1.43e-3)" "unprognostic (8.31e-2)" "unprognostic (1.04e-1)" "unprognostic (8.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.12e-1)" "unprognostic (1.08e-1)" 4.6 23.2 47.3 1.4 43.6 0.1 4.5 37.0 101.6 11.8 0.0 4.5 10.3 9.0 0.7 1.1 4.0 9.6 2.3 43.7 93.1 7.8 0.6 4.5 0.9 69.2 29.2 5.4 41.2 21.3 91.9 3.0 62.5 14.4 3.4 25.8 22.1 4.3 1.0 2.4 5.8 4.1 21.1 1.9 16.6 11.2 46.4 0.4 1.0 0.0 1.4 3.1 1.8 57.3 1.4 11.6 0.9 11.0 0.1 0.5 7.7 14.4 6.7 13.3 7.3 17.2 53.8 5.8 76.7 17.5 11.1 4.9 4.4 3.4 4.0 0.1 9.6 0.9 9.2 35.7 28.7 0.0 33.9 32.3 6.5 15.8 4.3 48.1 1.0 5.1 1.8 34.5 6.7 59.4 0.2 0.1 17.2 19.6 19.8 0.0 0.0 1.6 12.1 5.1 51.3 41.2 4.9 36.5 2.3 9.1 34.3 51.3 0.6 44.3 21.6 0.3 0.9 3.9 3.6 0.3 53.8 9.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 43.6 37.0 101.6 43.7 93.1 69.2 29.2 62.5 21.1 46.4 57.3 3.2 3.2 16.4 4.2 0.8 2.9 9.4 6.2 2.8 236.6 49.6 30.6 8.6 77.2 5.5 3.7 185.6 0.3 0.5 19.9 0.0 61.7 2.8 25.1 48.2 4.9 132.5 0.0 28.6 39.4 2.7 12.2 34.7 33.4 1.3 3.5 2.5 0.2 1.3 188.4 46.3 32.9 10.2 0.3 0.0 5.4 1.2 1.0 12.4 3.7 0.6 20.8 0.0 5.5 13.1 45.2 22.1 1.9 1.4 23.5 15.3 5.0 3.4 230.3 13.1 0.9 15.2 8.2 4.7 1.0 1.4 1.4 0.7 26.8 29.0 9.1 SLC24A2 NCKX2 ENSG00000155886 "Solute carrier family 24 member 2" Q9UI40 9 19507452-19786928 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 117.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 2710.1" "Group enriched" "Detected in some" 4 "breast cancer: 0.5;glioma: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 2.6;SCLC-21H: 2.2;U-87 MG: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079359 Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA079359: " "unprognostic (1.30e-1)" "unprognostic (8.57e-2)" "unprognostic (4.20e-1)" "unprognostic (1.05e-2)" "unprognostic (3.33e-2)" "unprognostic (1.48e-2)" "unprognostic (8.46e-2)" "unprognostic (8.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-2)" "unprognostic (6.51e-2)" "unprognostic (1.57e-2)" "unprognostic (2.08e-4)" "unprognostic (1.58e-1)" "unprognostic (2.11e-3)" "unprognostic (1.51e-2)" 0.1 5.9 28.4 0.0 64.7 0.1 0.0 42.3 64.6 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.5 0.1 0.0 19.2 19.1 0.1 0.0 0.0 0.0 81.3 36.3 0.0 0.0 0.0 0.8 0.1 87.7 0.1 0.0 18.7 0.0 0.0 0.1 0.1 0.0 0.0 19.4 0.1 0.1 0.2 81.9 0.0 0.0 0.3 0.0 0.0 0.0 117.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.0 28.4 64.7 42.3 64.6 19.2 19.1 81.3 36.3 87.7 19.4 81.9 117.1 0.0 0.0 0.0 18.9 0.1 0.0 0.0 0.0 0.0 58.7 0.0 0.0 2.3 0.0 0.0 0.0 273.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 668.6 0.0 0.1 0.9 0.0 0.1 0.0 0.0 1.4 0.0 0.1 97.6 637.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 25.3 0.0 4.1 0.0 217.6 2710.1 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 10.4 0.0 3.2 0.2 0.2 0.7 0.0 0.1 0.3 0.0 0.0 0.1 0.0 SLC27A6 "ACSVL2, FACVL2, FATP6, VLCS-H1" ENSG00000113396 "Solute carrier family 27 member 6" Q9Y2P4 5 128538013-129033642 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 24.4;fallopian tube: 21.3;heart muscle: 23.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 25.0;Cardiomyocytes: 29.6;Cytotrophoblasts: 54.8;Extravillous trophoblasts: 37.3;Muller glia cells: 33.0;Skeletal myocytes: 18.0;Syncytiotrophoblasts: 27.5" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 19.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BEWO: 43.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA008987 Approved Approved "Nuclear bodies" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies" "HPA008987: AB_1857065" "unprognostic (5.39e-5)" "unprognostic (4.79e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-1)" "unprognostic (3.55e-1)" "unprognostic (1.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.53e-1)" "unprognostic (2.64e-1)" "unprognostic (2.14e-1)" "unprognostic (2.54e-2)" "unprognostic (9.66e-4)" 0.4 24.4 1.8 0.3 2.4 0.1 3.0 3.0 1.4 3.9 0.7 0.9 0.4 4.3 0.2 4.2 21.3 2.7 23.5 1.2 3.6 0.0 0.1 0.8 0.2 9.7 5.2 9.7 0.1 0.0 6.0 6.7 7.5 3.6 1.7 7.4 3.5 0.3 0.4 2.0 1.1 0.8 5.8 0.1 0.5 13.0 5.5 9.6 1.8 0.9 5.7 1.1 2.9 8.4 0.0 0.0 0.1 0.0 0.0 0.0 43.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.9 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 3.5 0.0 3.3 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.3 0.3 4.4 0.0 5.1 0.0 3.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 3.0 1.4 1.2 3.6 9.7 5.2 7.5 5.8 5.5 8.4 0.0 0.0 0.0 0.0 0.0 3.2 0.9 0.0 25.0 0.6 0.2 5.5 29.6 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.0 13.2 3.8 1.0 0.3 0.0 0.0 0.4 0.0 37.3 2.7 0.0 1.9 0.0 1.7 0.0 0.0 3.8 3.3 4.6 0.0 0.0 0.0 0.4 2.8 0.3 0.2 0.0 0.0 0.0 33.0 0.0 1.0 1.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.9 0.0 18.0 0.3 1.1 1.0 1.8 0.9 27.5 0.0 2.3 0.1 0.1 SLC4A10 "NBCn2, NCBE" ENSG00000144290 "Solute carrier family 4 member 10" Q6U841 2 161424332-161985282 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.3;choroid plexus: 121.4;retina: 34.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 604.4;Inhibitory neurons: 560.9" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Region enhanced" "Detected in many" "cerebral cortex: 21.3" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 63.3" "Lineage enriched" "Detected in single" 65 "T-cells: 63.3" "Cell line enriched" "Detected in single" 11 "Karpas-707: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034755, HPA076725" Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA034755: AB_10670296, HPA076725: " "unprognostic (4.64e-4)" "unprognostic (3.88e-1)" "unprognostic (2.88e-2)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "unprognostic (7.89e-3)" "unprognostic (5.99e-4)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "unprognostic (1.64e-1)" "unprognostic (2.50e-2)" "unprognostic (9.27e-2)" "unprognostic (5.65e-2)" "unprognostic (9.23e-3)" "unprognostic (1.87e-1)" "unprognostic (2.10e-3)" "unprognostic (2.26e-1)" 0.0 2.0 6.3 0.7 10.3 0.2 0.2 0.2 21.3 0.1 121.4 1.8 0.3 0.0 1.3 0.0 0.6 0.4 0.0 11.8 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.5 0.0 1.3 0.0 0.0 0.2 1.3 34.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 2.5 0.0 63.3 0.0 1.2 7.8 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.5 6.3 10.3 0.2 21.3 11.8 1.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 21.2 0.1 0.0 0.0 0.0 0.0 116.3 0.0 0.0 0.6 0.0 0.0 0.0 8.4 0.0 2.6 1.1 0.0 0.0 18.3 0.0 0.0 0.3 0.0 0.0 604.4 0.0 0.0 0.0 0.5 0.0 2.5 0.0 1.8 0.6 0.0 0.0 560.9 2.8 0.0 0.6 0.0 10.5 0.0 0.1 0.0 16.9 0.5 2.8 1.0 129.2 16.5 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 9.4 0.0 0.3 0.0 SLC9A6 "KIAA0267, NHE6" ENSG00000198689 "Solute carrier family 9 member A6" Q92581 X 135973841-136047269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.3;Horizontal cells: 48.8;Inhibitory neurons: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059445, HPA059590" Enhanced Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA059445: AB_2684021, HPA059590: AB_2684075" "unprognostic (1.35e-1)" "unprognostic (8.28e-3)" "unprognostic (4.36e-1)" "unprognostic (4.93e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (2.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (7.07e-2)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (4.49e-2)" "unprognostic (5.06e-2)" 5.1 6.3 11.6 5.6 11.9 4.6 3.3 1.2 15.7 5.6 0.0 6.0 8.5 6.4 3.3 6.3 5.7 5.5 8.6 12.7 19.0 6.9 4.5 6.7 5.7 7.8 4.4 8.0 3.8 10.4 2.2 4.7 8.9 4.0 6.1 14.4 4.1 4.9 7.5 4.7 7.8 7.4 3.4 5.7 5.8 5.8 15.3 5.6 6.7 7.1 6.6 5.6 1.6 4.2 20.0 10.5 9.1 3.8 14.8 14.2 17.3 15.9 16.9 13.3 27.9 9.2 15.5 14.8 35.2 18.4 19.8 11.6 14.3 14.0 19.1 11.7 12.9 4.0 15.3 5.3 7.9 11.6 13.3 7.7 11.6 22.0 10.8 9.4 11.2 12.5 7.5 20.5 14.9 8.7 15.5 3.4 6.0 7.1 14.0 10.4 16.0 15.2 9.4 9.8 9.5 7.2 11.4 1.2 8.9 8.8 4.5 8.7 16.4 16.5 10.9 24.5 20.7 9.6 23.8 12.7 10.0 19.4 9.4 2.0 5.0 3.0 6.4 7.0 11.1 4.1 7.1 5.9 5.8 2.6 7.6 5.7 2.0 5.1 6.0 3.5 6.9 5.4 11.6 11.9 1.2 15.7 12.7 19.0 7.8 4.4 8.9 3.4 15.3 4.2 4.3 3.2 5.4 22.9 5.9 7.5 1.4 6.2 7.4 14.2 2.7 3.4 11.2 12.8 4.0 12.9 8.4 2.5 6.1 8.9 0.0 4.3 0.8 4.2 4.1 4.9 10.7 5.0 40.3 6.0 2.4 5.1 8.6 6.8 1.3 4.6 8.2 9.6 9.9 48.8 42.0 4.0 8.2 13.0 7.0 1.4 5.6 9.8 8.8 15.9 8.2 12.9 4.1 19.6 22.7 6.1 6.0 4.5 3.8 2.0 10.3 6.0 3.1 7.8 0.0 5.1 8.4 9.0 11.9 7.0 6.8 2.9 8.9 3.1 6.0 3.1 SNCB ENSG00000074317 "Synuclein beta" Q16143 5 176620082-176630556 "Human disease related genes, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 439.2;retina: 182.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 105.1;Excitatory neurons: 36.8;Horizontal cells: 50.5;Inhibitory neurons: 32.6;Rod photoreceptor cells: 49.7" "Cancer enriched" "Detected in some" 8 "glioma: 11.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "SCLC-21H: 54.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002681, HPA035876" Enhanced Supported NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "CAB002681: , HPA035876: AB_10670592" "unprognostic (3.55e-2)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" "unprognostic (1.46e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (3.41e-1)" "unprognostic (2.39e-1)" "unprognostic (2.29e-3)" "unprognostic (3.31e-1)" "unprognostic (5.41e-5)" "unprognostic (1.31e-3)" "unprognostic (8.57e-2)" "unprognostic (2.81e-1)" "unprognostic (8.42e-3)" 0.1 3.2 81.7 0.0 154.5 0.0 0.1 74.3 439.2 0.1 0.0 1.0 0.1 0.1 0.0 0.1 0.0 0.0 1.5 136.3 41.9 0.1 0.2 0.2 0.2 104.2 23.8 0.3 0.8 0.0 17.1 0.0 77.7 0.1 0.0 182.2 0.1 0.0 1.9 0.3 0.4 0.0 1.3 0.2 0.3 0.6 63.1 0.0 0.2 2.8 0.0 0.1 0.1 237.7 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.7 0.0 6.0 0.3 2.7 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.3 1.8 1.0 0.0 0.0 3.9 0.0 2.3 0.0 0.0 0.3 0.0 0.0 54.6 2.0 0.0 0.2 5.4 0.1 2.5 0.3 0.0 0.0 2.2 0.0 0.0 0.7 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.7 154.5 74.3 439.2 136.3 41.9 104.2 23.8 77.7 1.3 63.1 237.7 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 105.1 0.0 0.0 1.5 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 50.5 32.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.5 0.0 10.3 0.0 3.5 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.7 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SV2A "KIAA0736, SV2" ENSG00000159164 "Synaptic vesicle glycoprotein 2A" Q7L0J3 1 149903318-149917844 "FDA approved drug targets, Predicted membrane proteins" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 128.2;parathyroid gland: 48.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.9;Excitatory neurons: 63.4;Horizontal cells: 95.9;Inhibitory neurons: 107.2" "Cancer enriched" "Detected in many" 6 "glioma: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002226, HPA007863" Enhanced Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "CAB002226: AB_564144, HPA007863: AB_1080135" "unprognostic (8.05e-3)" "unprognostic (3.86e-3)" "unprognostic (2.24e-1)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (2.02e-1)" "unprognostic (6.24e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (9.00e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.44e-2)" "unprognostic (9.86e-2)" "unprognostic (1.95e-2)" "unprognostic (4.81e-3)" 1.5 8.9 59.2 2.9 64.7 6.0 1.6 30.2 128.2 6.9 0.0 4.5 1.5 8.4 23.4 1.6 4.8 3.3 1.5 65.1 61.6 1.7 0.5 2.0 2.1 68.2 40.2 3.5 1.4 48.4 22.9 1.4 61.2 4.2 1.8 38.6 1.3 3.7 0.5 0.9 3.0 8.0 14.1 1.6 2.5 1.1 48.9 3.8 4.4 0.5 1.7 3.1 3.9 67.5 0.3 0.0 26.0 0.1 2.6 7.4 2.8 11.2 38.8 32.6 46.7 0.8 1.2 0.3 9.9 16.9 34.3 0.6 0.3 2.4 27.9 0.1 6.2 35.2 2.0 2.0 24.5 0.3 0.5 16.7 0.2 52.3 3.9 36.2 2.9 31.7 0.4 35.8 21.8 0.3 34.8 1.7 66.3 0.0 0.2 12.0 16.4 0.7 0.2 0.9 54.2 43.8 0.1 0.4 25.6 24.6 0.4 21.4 0.2 30.1 29.9 1.2 41.3 0.2 0.5 0.2 53.0 0.3 12.3 0.4 0.1 0.0 0.3 0.0 0.3 0.1 0.3 0.2 0.0 0.2 0.1 0.4 0.3 0.3 0.0 0.1 0.6 0.1 59.2 64.7 30.2 128.2 65.1 61.6 68.2 40.2 61.2 14.1 48.9 67.5 0.8 0.0 1.1 12.4 0.3 0.1 1.9 0.7 4.6 111.9 0.7 4.2 0.8 1.5 0.1 0.0 4.2 0.3 0.7 0.3 0.0 0.1 0.6 0.4 4.6 2.4 4.2 2.1 63.4 0.4 0.6 3.3 1.5 1.3 0.0 10.9 7.5 0.1 0.3 95.9 107.2 0.4 0.0 0.0 0.9 0.2 0.0 0.3 0.0 7.5 0.0 22.9 0.0 28.1 15.7 0.2 0.1 5.7 0.5 0.9 0.1 0.1 0.9 16.1 0.0 2.7 4.9 1.3 0.9 0.4 0.4 0.4 2.7 3.0 0.5 0.7 TMEM114 ENSG00000232258 "Transmembrane protein 114" B3SHH9 16 8537605-8590193 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "seminal vesicle: 19.6" "Cell type enhanced" "Detected in single" "Microglial cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hypothalamus: 6.6" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.72e-5)" "unprognostic (2.26e-1)" "unprognostic (3.98e-3)" "unprognostic (7.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.62e-1)" "unprognostic (2.21e-1)" 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 0.6 0.0 2.9 0.1 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 3.1 1.1 1.7 2.9 0.3 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM63C "C14orf171, CSC1, DKFZp434P0111, hsCSC1" ENSG00000165548 "Transmembrane protein 63C" Q9P1W3 14 77116568-77259495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7;pituitary gland: 41.9" "Cell type enhanced" "Detected in some" "Early spermatids: 9.5;Enteroendocrine cells: 19.2;Excitatory neurons: 25.8;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 16.1" "Cancer enhanced" "Detected in many" "breast cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.5;Karpas-707: 24.1;RPMI-8226: 12.7;SCLC-21H: 32.5;SK-BR-3: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030657 Uncertain Approved Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "HPA030657: AB_10601699" "unprognostic (2.74e-1)" "unprognostic (1.79e-2)" "unprognostic (2.30e-1)" "unprognostic (4.30e-8)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (2.68e-3)" "unprognostic (1.61e-3)" "unprognostic (2.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.90e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.34e-7)" "unprognostic (5.90e-3)" 0.2 9.6 9.2 0.6 5.9 0.8 3.3 28.7 10.5 2.6 0.0 4.5 1.2 0.1 4.5 6.4 0.2 0.2 0.9 5.6 24.6 0.5 0.1 0.5 0.3 4.5 8.3 0.1 4.8 1.5 41.9 0.7 16.9 0.2 3.0 2.4 2.7 0.0 0.5 9.7 2.7 0.6 4.2 3.3 1.9 11.3 18.2 0.1 2.2 0.4 0.3 0.0 7.1 4.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 18.5 3.4 0.0 3.0 2.5 3.8 1.5 0.0 1.2 1.4 0.3 1.8 0.0 0.0 3.2 0.1 0.0 7.5 0.0 0.2 0.0 0.0 8.7 0.0 24.1 0.0 9.3 2.6 0.1 0.8 0.0 0.0 0.0 1.2 12.7 0.3 0.0 32.5 4.9 0.4 29.1 0.0 0.6 2.8 1.6 0.0 0.0 5.9 0.0 0.0 1.9 0.1 0.7 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 0.1 9.2 5.9 28.7 10.5 5.6 24.6 4.5 8.3 16.9 4.2 18.2 4.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 3.3 2.2 0.8 0.7 0.0 1.7 0.0 2.1 0.0 1.5 3.8 1.9 0.0 9.5 0.3 0.4 0.1 19.2 0.0 25.8 0.2 0.1 0.3 0.0 2.4 0.0 0.2 0.0 0.0 2.7 3.3 22.2 3.0 4.1 0.0 0.0 6.2 0.0 0.2 0.0 3.7 0.6 0.3 0.0 16.1 1.1 0.2 7.0 0.4 0.1 0.0 0.5 0.2 0.1 0.6 0.0 0.0 0.3 0.6 0.1 2.4 0.0 0.0 0.2 0.7 0.7 0.1 UNC79 KIAA1409 ENSG00000133958 "Unc-79 homolog, NALCN channel complex subunit" Q9P2D8 14 93333219-93707876 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;pituitary gland: 11.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 524.0;Inhibitory neurons: 463.6;Oligodendrocyte precursor cells: 270.4;Oligodendrocytes: 202.6" "Cancer enhanced" "Detected in some" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "REH: 4.3;SCLC-21H: 3.0;SH-SY5Y: 1.9;U-937: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071881 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA071881: AB_2732189" "unprognostic (8.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.70e-2)" "unprognostic (6.91e-2)" "unprognostic (1.06e-1)" "unprognostic (7.73e-2)" "unprognostic (2.99e-2)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (5.73e-3)" "unprognostic (8.03e-3)" "unprognostic (2.87e-1)" "unprognostic (3.39e-2)" "unprognostic (2.66e-2)" "unprognostic (5.57e-2)" "unprognostic (3.03e-2)" "unprognostic (7.47e-2)" 0.0 0.7 2.2 0.0 2.8 0.0 0.0 5.1 4.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 2.1 1.9 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.2 11.7 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 2.5 0.4 0.0 0.1 0.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.3 0.0 0.0 0.1 0.1 3.0 1.9 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.8 5.1 4.7 2.1 1.9 0.0 0.1 0.0 0.0 0.4 2.3 0.3 0.0 0.0 89.8 0.4 0.3 0.3 0.5 0.0 41.9 0.3 0.3 2.8 0.0 0.1 0.0 10.4 0.1 0.3 0.7 0.0 0.3 36.9 4.8 0.9 0.6 0.0 0.4 524.0 0.2 0.1 0.6 1.1 0.8 0.0 0.3 0.4 0.2 0.3 40.4 463.6 0.3 0.0 0.6 0.4 16.4 0.6 0.4 0.0 23.4 0.1 2.1 0.0 270.4 202.6 0.4 0.1 0.4 0.0 0.3 0.6 1.9 0.9 5.7 0.0 0.5 0.8 3.4 2.5 0.2 0.3 0.7 0.2 0.5 0.2 0.3 VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 1407.4" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 128.3;Horizontal cells: 225.4" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Region enriched" "Detected in all" 6 "hypothalamus: 1407.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 172.0;SK-MEL-30: 511.5;U-2 OS: 85.9;WM-115: 141.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1270000 3100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavorable (4.25e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" 2.1 3.1 23.7 0.8 24.8 0.1 0.1 5.5 174.6 0.0 0.0 0.5 0.1 0.7 0.0 0.0 0.0 0.0 0.1 22.7 1407.4 3.6 0.0 0.1 0.0 235.4 69.9 0.1 16.1 0.0 117.0 0.0 158.8 0.1 0.0 2.2 0.0 0.0 0.0 0.8 0.3 0.2 16.6 0.1 1.9 0.9 48.7 0.0 0.6 0.0 0.0 0.0 0.1 27.3 2.2 1.1 1.1 9.5 0.0 0.0 10.3 0.9 0.0 0.0 0.0 2.4 0.9 0.1 3.1 0.0 1.4 1.4 0.5 0.1 0.0 1.0 0.7 0.3 0.0 0.9 0.1 0.6 4.4 0.1 0.2 0.2 0.7 0.0 0.0 0.1 3.7 2.3 0.0 23.4 0.1 2.4 17.6 1.0 2.3 0.8 0.0 0.1 0.3 0.1 14.1 172.0 0.3 0.9 511.5 1.1 0.4 0.3 0.0 0.4 85.9 0.0 2.0 0.1 0.8 4.7 13.5 0.4 141.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 24.8 5.5 174.6 22.7 1407.4 235.4 69.9 158.8 16.6 48.7 27.3 1.7 0.0 0.0 3.6 0.9 1.5 1.0 0.0 1.2 22.0 0.9 0.6 2.9 0.0 0.0 0.0 0.0 1.5 1.0 1.3 29.4 0.3 0.1 0.4 0.4 0.9 128.3 0.0 22.7 0.0 8.4 0.3 3.1 0.5 0.0 1.4 0.0 0.0 0.6 225.4 37.7 4.5 0.0 0.0 0.4 0.6 0.6 0.7 0.0 11.2 0.0 2.1 0.0 4.0 4.8 5.9 2.8 0.0 0.9 4.3 2.7 1.2 0.0 5.0 0.0 0.1 0.8 0.2 4.3 0.6 2.3 1.4 0.5 5.4 2.3 0.6