Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24920237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 58.4;Sertoli cells: 111.7;Smooth muscle cells: 62.8;Theca cells: 92.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010223 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010223: AB_630839" "unprognostic (3.05e-1)" "unprognostic (1.10e-1)" "unprognostic (4.91e-2)" "unprognostic (1.39e-3)" "unprognostic (5.01e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-1)" "unprognostic (6.06e-2)" "unprognostic (8.43e-2)" "unprognostic (6.89e-2)" "unprognostic (8.22e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.32e-9)" "unprognostic (3.74e-2)" "unprognostic (5.56e-2)" "unprognostic (1.11e-1)" "unprognostic (8.55e-3)" 94.4 17.3 43.5 17.3 55.1 17.7 74.6 36.7 50.1 66.7 28.4 27.5 10.9 56.4 20.5 30.4 62.1 23.0 36.6 43.3 43.4 25.9 6.6 42.5 18.9 41.6 43.8 71.9 15.7 17.0 41.7 83.6 41.1 40.6 15.8 4.2 21.6 33.0 15.2 38.4 34.4 35.3 36.9 30.4 25.0 9.8 50.6 11.4 36.8 20.4 18.1 36.4 48.9 44.9 76.5 40.4 17.2 28.3 84.5 75.4 29.6 32.3 65.9 37.1 37.8 38.6 25.1 26.0 6.2 53.2 51.0 54.5 43.1 54.5 24.0 58.4 55.8 43.0 40.0 1.7 64.0 24.0 24.6 55.7 47.5 36.6 50.8 23.6 33.8 27.9 15.5 49.2 19.3 43.6 17.9 2.1 14.9 39.9 24.4 38.8 75.3 59.5 15.5 38.7 31.6 19.1 45.8 54.2 30.2 13.0 13.5 22.5 33.5 59.7 34.2 39.1 54.1 42.4 101.6 113.6 18.7 39.2 31.4 2.6 1.5 0.0 0.4 1.6 0.3 5.5 0.9 0.5 9.5 6.0 0.7 0.5 0.0 1.2 0.4 9.0 3.4 1.0 43.5 55.1 36.7 50.1 43.3 43.4 41.6 43.8 41.1 36.9 50.6 44.9 14.6 0.0 1.8 17.0 8.2 11.0 4.2 4.1 5.2 3.0 18.6 8.0 2.8 0.0 1.3 1.8 0.0 1.0 5.2 5.0 0.0 0.9 0.3 1.9 42.2 10.6 1.2 5.2 40.1 0.0 2.1 25.5 2.0 2.2 18.4 3.7 5.0 0.3 12.6 0.0 36.8 6.0 2.0 5.4 6.9 3.9 58.4 10.1 7.2 21.5 4.0 1.6 0.0 15.1 33.2 1.0 5.8 29.3 4.9 11.2 8.3 0.2 1.1 2.2 111.7 6.5 62.8 0.4 2.4 4.4 11.8 1.2 7.2 92.9 12.1 3.9 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 216.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.5;Exocrine glandular cells: 170.7;NK-cells: 208.1;Syncytiotrophoblasts: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.3" "Lineage enriched" "Detected in many" 5 "T-cells: 160.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 218.4;SK-BR-3: 277.7;SK-MEL-30: 297.8;TIME: 241.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" NA NA 32000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" 50.9 13.2 79.6 12.7 67.7 19.6 50.5 46.9 115.2 36.3 0.0 36.7 26.1 19.7 84.2 46.7 52.2 69.6 36.8 68.7 71.5 158.9 4.2 37.3 5.2 64.6 76.2 5.3 59.8 28.4 17.7 101.3 73.9 31.7 33.4 6.6 92.2 57.5 15.7 87.5 19.3 19.8 54.8 12.3 47.9 45.4 92.5 28.9 216.3 16.9 15.6 37.1 37.8 51.6 41.8 47.1 12.0 0.6 0.0 0.1 127.7 8.5 3.9 14.4 2.6 34.7 218.4 0.2 110.5 8.2 196.1 149.1 0.0 103.4 5.1 1.6 0.0 5.1 56.0 39.3 0.3 0.4 2.1 2.4 143.8 24.5 10.2 15.8 118.1 1.0 0.1 1.2 3.2 51.4 107.3 0.8 1.7 143.3 42.6 3.8 1.4 30.8 209.4 134.9 38.2 1.2 2.0 277.7 297.8 8.4 123.8 0.8 241.4 25.6 38.0 1.5 96.2 0.2 2.1 0.6 200.5 0.7 62.9 2.9 0.8 0.2 160.3 0.5 1.9 0.3 10.5 62.6 0.2 0.1 5.3 45.2 3.3 30.6 0.7 0.3 0.2 37.1 79.6 67.7 46.9 115.2 68.7 71.5 64.6 76.2 73.9 54.8 92.5 51.6 107.7 9.6 11.9 113.9 3.7 0.0 24.1 0.0 11.4 0.9 29.6 27.2 4.3 15.7 21.7 79.1 0.0 222.5 120.4 17.7 27.4 33.9 74.0 24.6 4.3 53.9 20.6 17.7 3.5 170.7 25.1 4.7 29.0 45.2 5.1 88.2 30.0 0.5 22.8 0.0 4.9 23.2 0.0 3.5 0.0 31.3 3.1 6.1 0.0 41.2 1.1 4.8 208.1 85.5 1.3 101.1 12.3 0.0 19.1 15.2 5.6 132.6 16.8 0.5 0.0 1.6 7.1 2.7 0.9 23.0 0.0 186.5 35.1 0.4 24.6 19.5 ADM5 "AM5, C19orf76" ENSG00000224420 "Adrenomedullin 5 (putative)" C9JUS6 19 49688664-49690575 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 29.3;Endothelial cells: 47.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 18.0" "Secreted to blood" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.34e-2)" "unprognostic (2.56e-1)" "unprognostic (3.08e-3)" "unprognostic (5.62e-2)" "unprognostic (2.18e-2)" "unprognostic (2.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.39e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (1.47e-2)" "unprognostic (8.94e-2)" "unprognostic (4.21e-11)" "unprognostic (2.39e-2)" "unprognostic (9.25e-2)" "unprognostic (9.92e-3)" "prognostic favorable (6.74e-4)" 7.8 0.8 1.9 0.7 1.9 1.3 6.0 4.5 2.9 3.7 1.5 2.4 0.8 4.3 0.3 3.3 5.0 0.6 1.8 2.0 1.9 3.5 1.8 4.3 1.0 1.9 1.9 2.0 1.8 0.1 2.7 0.7 2.2 3.9 0.2 1.5 2.6 0.4 3.9 5.0 2.9 0.8 1.8 6.7 2.3 3.0 2.2 0.7 2.6 0.4 0.7 3.6 3.6 1.9 3.4 5.7 3.3 2.3 0.1 0.0 3.9 0.3 0.3 1.1 0.6 6.6 3.1 5.1 1.2 0.2 0.3 1.0 5.9 1.9 0.4 6.0 11.3 5.8 1.6 4.3 0.1 1.7 3.8 0.6 4.2 0.7 0.5 0.8 1.1 5.4 4.2 3.7 0.2 5.4 2.6 18.0 4.4 0.6 1.6 7.4 2.5 5.3 0.5 5.9 2.0 0.9 0.8 1.6 1.6 0.8 3.6 2.5 0.9 1.8 6.6 0.9 1.4 12.6 10.7 5.9 1.2 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 4.5 2.9 2.0 1.9 1.9 1.9 2.2 1.8 2.2 1.9 29.3 0.0 1.5 1.3 1.4 6.1 1.4 1.4 6.2 4.3 5.4 6.1 0.1 1.5 1.5 0.0 0.0 0.5 1.0 1.8 0.0 0.5 8.1 3.0 1.9 47.3 1.2 0.0 0.3 1.1 0.5 2.2 1.5 6.0 0.0 0.7 5.0 0.3 0.3 0.0 0.4 1.5 0.0 1.0 4.9 4.3 0.6 1.3 5.4 0.0 0.2 0.9 0.0 0.0 0.9 0.6 0.4 0.7 0.2 1.9 0.3 0.0 1.6 2.4 0.0 2.9 1.5 1.1 1.2 6.2 6.3 0.1 1.3 0.3 1.6 1.1 ADRA2B "ADRA2L1, ADRA2RL1, ADRARL1" ENSG00000274286 "Adrenoceptor alpha 2B" P18089 2 96112876-96116571 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 9.0;Langerhans cells: 8.0;Sertoli cells: 32.9;Smooth muscle cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;EFO-21: 1.0" "Group enriched" "Detected in some" 6 "basal ganglia: 2.5;cerebellum: 1.0;thalamus: 3.2" "Low region specificity" "Detected in some" "HPA066029, HPA074948" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Cytosol "HPA066029: AB_2685599, HPA074948: " "unprognostic (6.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.76e-2)" "unprognostic (4.93e-4)" "unprognostic (1.84e-2)" "unprognostic (5.24e-2)" "unprognostic (6.80e-5)" "unprognostic (4.85e-2)" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (2.21e-1)" "unprognostic (4.43e-2)" "unprognostic (3.39e-1)" "unprognostic (1.36e-1)" "unprognostic (6.55e-2)" 6.4 2.1 1.5 0.3 1.7 0.8 3.0 1.4 2.7 1.5 4.9 2.3 0.3 1.9 3.8 0.7 3.0 0.6 10.1 1.2 1.4 5.1 7.0 0.5 0.2 1.8 1.6 1.7 0.8 0.5 0.5 0.8 1.7 1.4 0.3 0.0 2.2 1.5 6.4 1.9 2.6 0.7 1.3 8.6 2.2 1.6 2.6 0.2 1.3 5.0 0.1 2.5 1.8 2.4 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.4 2.7 1.2 1.4 1.8 1.6 1.7 1.3 2.6 2.4 2.9 0.0 0.0 0.0 0.9 1.1 0.7 0.7 0.6 0.0 0.9 0.9 2.5 0.0 1.5 1.8 0.0 0.8 2.9 0.1 0.0 0.2 0.0 2.2 1.0 2.4 2.4 0.0 0.0 0.6 0.2 1.0 1.1 9.0 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.2 0.0 0.3 8.0 0.0 1.8 5.1 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.4 0.7 0.0 0.1 1.4 0.0 32.9 0.7 13.3 0.0 0.3 0.6 1.4 0.4 2.8 0.1 0.1 0.3 ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 196.1;Basal keratinocytes: 387.5;Basal respiratory cells: 146.6;Squamous epithelial cells: 276.0;Suprabasal keratinocytes: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 72.4;hTERT-HME1: 74.1;PC-3: 31.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003431, HPA075322" Uncertain Uncertain Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA003431: AB_1845333, HPA075322: " "unprognostic (2.28e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-3)" "unprognostic (5.54e-2)" "unprognostic (2.34e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (3.15e-9)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" 19.5 1.6 4.5 3.2 4.7 12.5 18.7 5.1 4.4 13.5 1.8 2.3 1.9 2.3 1.7 15.1 4.1 3.8 6.7 5.3 4.2 1.1 14.2 19.5 4.1 6.0 5.6 0.9 1.2 2.2 0.3 9.9 6.2 9.0 2.8 0.6 4.2 1.5 11.7 21.8 2.1 3.7 6.2 7.9 7.5 0.5 7.1 2.7 1.0 8.6 6.0 6.8 7.2 7.6 23.3 0.1 0.1 0.0 0.8 0.2 0.0 4.3 13.2 6.0 6.7 0.0 9.7 0.1 6.1 1.3 21.5 20.0 0.0 27.9 6.9 0.0 0.6 0.0 5.1 0.0 0.6 0.1 11.0 0.1 72.4 2.0 74.1 5.0 2.8 0.0 0.1 8.3 16.0 0.0 0.0 12.9 0.4 0.2 31.2 6.7 4.1 13.0 3.2 5.8 0.1 0.1 5.4 0.4 2.0 2.5 0.0 7.0 12.3 0.0 5.0 7.2 3.5 1.9 0.0 0.2 0.0 15.1 2.6 16.5 21.8 67.8 151.4 37.1 112.3 21.5 34.3 93.0 24.7 15.6 5.8 53.3 35.4 37.2 53.3 28.4 2.3 53.4 4.5 4.7 5.1 4.4 5.3 4.2 6.0 5.6 6.2 6.2 7.1 7.6 196.1 112.2 31.6 1.6 16.5 387.5 36.6 146.6 127.5 0.5 23.3 15.2 18.6 0.0 67.4 0.0 0.0 0.4 59.2 3.7 0.0 2.4 0.5 3.2 0.5 40.3 3.0 1.3 0.0 0.2 0.3 6.2 35.7 3.0 118.6 0.1 6.8 14.1 17.7 0.0 0.0 3.1 16.2 20.8 54.9 0.7 0.0 21.1 30.2 15.9 4.0 4.1 90.6 0.0 0.1 8.6 0.1 0.0 23.2 23.5 0.1 0.1 27.8 5.0 0.0 19.8 9.6 0.7 0.1 276.0 245.4 0.5 40.1 0.1 3.5 61.5 AFAP1L1 FLJ36748 ENSG00000157510 "Actin filament associated protein 1 like 1" Q8TED9 5 149271859-149343637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.6" "Cell type enhanced" "Detected in many" "Adipocytes: 62.4;Cardiomyocytes: 39.3;Early spermatids: 105.4;Endothelial cells: 72.0;Extravillous trophoblasts: 47.1;Hepatic stellate cells: 47.2;Late spermatids: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.6;HUVEC TERT2: 20.8;TIME: 33.9;WM-115: 79.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.91e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.20e-1)" "unprognostic (3.44e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-3)" "unprognostic (5.25e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (4.00e-1)" "unprognostic (9.64e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-3)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (9.88e-2)" 23.9 2.8 1.7 2.1 0.9 0.1 15.2 1.1 1.3 4.2 1.0 3.5 0.8 7.1 0.6 4.3 10.1 4.0 26.1 0.9 1.0 4.1 2.1 13.3 2.3 1.4 1.1 3.3 1.0 6.1 2.4 14.4 1.4 3.3 0.7 1.3 3.4 1.9 31.6 6.0 3.4 3.5 1.1 2.9 2.4 2.3 1.8 3.4 7.4 16.6 0.8 4.6 3.7 0.9 7.0 2.4 0.1 0.3 9.9 2.1 42.6 1.5 5.5 5.4 8.9 0.1 4.1 0.0 3.3 2.5 13.7 1.4 0.8 6.2 2.2 0.0 1.0 1.6 0.9 0.0 5.2 0.0 0.1 7.3 1.0 3.0 11.6 4.3 20.8 0.0 0.0 0.2 2.1 0.0 0.0 0.0 1.0 0.0 5.4 0.0 0.0 0.0 3.5 1.1 0.7 1.1 4.4 0.1 14.8 1.5 0.2 0.4 33.9 2.5 7.7 0.1 1.2 0.0 0.0 0.0 0.5 0.1 79.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.9 1.1 1.3 0.9 1.0 1.4 1.1 1.4 1.1 1.8 0.9 62.4 0.0 1.3 0.3 0.2 1.5 1.4 4.6 0.0 0.3 0.4 0.5 39.3 1.5 4.1 0.0 0.0 14.2 0.2 0.0 0.0 0.3 105.4 0.3 0.4 72.0 0.0 0.0 2.9 0.0 47.1 4.5 0.0 0.2 1.3 0.0 47.2 0.6 2.7 0.0 1.2 0.0 0.0 4.2 1.3 50.4 9.6 0.7 7.2 10.3 0.0 0.5 0.0 2.0 0.3 0.0 0.0 15.8 0.0 4.0 0.0 0.8 6.4 5.3 13.1 4.6 4.0 0.5 4.8 0.3 1.4 6.4 0.5 1.8 0.0 5.4 AIF1L "C9orf58, FLJ12783, IBA2" ENSG00000126878 "Allograft inflammatory factor 1 like" Q9BQI0 9 131096476-131123152 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 284.4;kidney: 313.2;lymphoid tissue: 206.8" "Group enriched" "Detected in many" 4 "Adipocytes: 122.9;Collecting duct cells: 356.8;Distal tubular cells: 289.5;Extravillous trophoblasts: 383.2;Proximal tubular cells: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 140.3;MCF7: 96.7;NTERA-2: 106.7;RPTEC TERT1: 299.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020522, HPA056852" Enhanced NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" "HPA020522: AB_2670463, HPA056852: AB_2683256" "unprognostic (2.59e-2)" "unprognostic (1.83e-3)" "unprognostic (2.55e-2)" "unprognostic (2.81e-2)" "unprognostic (1.78e-2)" "unprognostic (2.01e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.77e-1)" "unprognostic (4.39e-1)" "unprognostic (2.81e-2)" "unprognostic (2.68e-1)" "prognostic favorable (5.54e-6)" "unprognostic (2.48e-2)" "unprognostic (2.37e-1)" "unprognostic (1.38e-2)" "unprognostic (6.20e-2)" 44.7 4.8 165.6 4.7 199.6 2.3 39.9 179.6 284.4 20.2 101.5 7.2 1.3 13.5 9.3 105.8 10.8 8.3 41.8 145.4 160.9 313.2 1.6 12.2 1.9 209.2 204.2 5.1 6.5 80.6 18.2 23.8 196.2 6.6 5.7 6.9 32.1 36.6 14.6 15.9 7.9 10.0 172.9 206.8 9.0 6.5 188.0 3.9 91.9 21.9 5.8 9.2 35.3 225.1 0.5 2.2 140.3 24.1 0.0 0.0 59.5 0.0 0.3 0.1 0.3 26.8 11.3 0.0 63.5 0.0 3.0 13.5 21.2 1.5 0.8 0.3 30.0 15.7 7.4 51.4 0.3 0.1 7.6 1.2 6.6 0.5 0.7 0.4 6.7 39.3 10.6 0.1 0.0 96.7 9.3 1.9 106.7 9.0 10.1 0.2 1.9 39.6 299.9 8.5 54.3 8.7 7.4 60.0 20.4 82.7 57.6 0.9 0.9 3.8 10.2 0.5 30.8 0.4 0.5 0.4 6.1 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 165.6 199.6 179.6 284.4 145.4 160.9 209.2 204.2 196.2 172.9 188.0 225.1 122.9 0.0 0.0 5.9 2.8 4.1 2.1 1.5 1.2 0.1 45.0 29.5 6.6 0.0 3.5 356.8 0.0 4.5 1.3 0.8 289.5 1.5 1.0 4.1 3.5 35.0 3.6 0.0 0.3 0.8 383.2 15.5 0.5 15.0 0.0 10.1 33.5 0.0 7.0 0.0 0.3 2.1 2.0 0.3 2.0 3.5 37.6 2.3 67.6 21.5 0.0 15.1 0.0 8.0 36.3 2.9 0.3 59.0 0.0 7.7 0.0 201.5 0.6 0.2 0.0 3.3 10.3 0.2 5.3 4.4 2.4 21.1 1.7 29.9 1.3 2.0 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ANXA2R "AXIIR, C5orf39" ENSG00000177721 "Annexin A2 receptor" Q3ZCQ2 5 43039233-43043170 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.8;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 32.2;B-cells: 23.8;dendritic cells: 36.4;Endothelial cells: 24.8;Hepatic stellate cells: 38.2;NK-cells: 47.4;T-cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "gdT-cell: 53.9;MAIT T-cell: 63.5;memory B-cell: 34.3;memory CD4 T-cell: 56.1;memory CD8 T-cell: 59.9;naive B-cell: 32.9;naive CD4 T-cell: 96.3;naive CD8 T-cell: 72.1;NK-cell: 24.8;T-reg: 66.5" "Group enriched" "Detected in all" 6 "B-cells: 34.3;NK-cells: 24.8;T-cells: 96.3" "Cell line enhanced" "Detected in many" "HSkMC: 27.7;JURKAT: 33.1;MOLT-4: 30.0;REH: 30.9;U-937: 117.7" HPA051482 Uncertain Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA051482: AB_2681500" "unprognostic (3.38e-2)" "unprognostic (2.00e-3)" "unprognostic (1.21e-2)" "unprognostic (1.92e-2)" "unprognostic (1.40e-2)" "unprognostic (3.92e-3)" "unprognostic (5.65e-3)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (8.14e-2)" "unprognostic (2.13e-2)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.36e-8)" "unprognostic (2.68e-1)" "unprognostic (2.77e-1)" "unprognostic (2.68e-1)" "unprognostic (1.68e-1)" 4.7 1.3 3.2 12.1 3.2 19.8 3.9 3.0 3.8 3.5 3.5 2.5 3.3 2.4 1.7 1.8 3.3 3.5 2.9 2.8 2.9 2.0 1.3 4.6 26.1 3.4 3.3 1.2 0.8 0.6 1.1 3.2 3.2 2.7 2.7 0.1 1.7 1.2 2.5 2.1 8.2 2.1 3.5 15.8 3.3 1.5 3.3 25.2 2.7 3.0 17.2 3.2 3.8 4.0 2.1 2.1 1.6 1.2 2.6 8.0 0.4 0.5 0.3 0.5 0.6 3.9 1.9 6.8 6.5 1.6 2.2 0.8 5.0 0.5 0.5 13.3 4.0 2.2 5.9 1.8 4.1 2.6 0.8 27.7 0.2 2.4 0.2 0.1 16.2 33.1 1.5 8.9 2.1 3.1 30.0 4.1 0.0 1.7 14.8 30.9 3.6 3.9 0.7 1.1 5.7 0.0 2.7 0.7 0.7 0.2 0.7 4.9 9.9 0.5 0.0 0.8 2.5 4.4 6.7 3.3 3.6 117.7 1.4 5.6 3.5 1.7 53.9 2.5 63.5 34.3 56.1 59.9 3.5 32.9 96.3 72.1 3.2 24.8 8.1 5.2 66.5 26.6 3.2 3.2 3.0 3.8 2.8 2.9 3.4 3.3 3.2 3.5 3.3 4.0 32.2 0.0 9.9 0.0 23.8 3.7 1.4 0.3 2.2 0.1 1.9 2.2 1.3 4.3 1.5 0.0 0.0 0.4 36.4 0.5 0.0 0.1 4.0 1.1 5.0 24.8 1.8 8.2 0.0 0.0 1.1 7.2 1.5 0.8 15.2 4.1 38.2 1.4 8.7 0.0 0.0 0.1 2.0 18.2 5.6 1.5 1.5 7.5 7.2 0.0 7.1 0.2 47.4 0.0 0.0 0.1 0.0 0.4 7.8 1.2 1.0 0.4 2.0 0.0 0.0 3.4 3.7 0.7 1.6 1.2 2.3 0.4 66.0 0.3 0.5 1.4 APOL3 "APOLIII, CG12-1" ENSG00000128284 "Apolipoprotein L3" O95236 22 36140330-36166177 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 59.1;Endothelial cells: 69.8;Hepatic stellate cells: 69.7;Kupffer cells: 38.7;NK-cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 34.1;ASC TERT1: 54.1;HDLM-2: 25.6;Karpas-707: 59.0" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "prognostic favorable (6.82e-4)" "unprognostic (5.93e-3)" "unprognostic (6.79e-2)" "unprognostic (2.70e-2)" "unprognostic (2.22e-1)" "unprognostic (7.05e-2)" "unprognostic (6.30e-2)" "unprognostic (2.67e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (7.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" 58.2 12.3 10.1 25.4 10.0 10.1 43.7 8.7 12.2 17.2 7.6 16.3 15.0 18.8 12.3 12.0 24.4 14.3 33.7 8.8 9.1 19.0 39.9 42.0 43.4 11.4 10.1 9.6 6.3 3.4 8.5 16.3 10.0 18.4 11.4 0.6 15.7 14.9 16.6 19.6 21.7 16.0 8.8 47.6 12.3 2.9 10.8 18.1 25.2 19.6 20.8 17.6 19.5 8.7 4.3 0.0 0.0 0.1 34.1 54.1 1.8 1.8 10.2 3.1 7.0 0.0 9.5 2.1 0.4 5.0 4.6 0.7 0.0 1.3 1.9 25.6 0.0 9.2 1.3 2.1 18.3 0.1 2.6 11.4 0.0 9.0 0.4 2.1 22.1 2.0 0.2 59.0 1.1 0.1 11.7 0.3 0.1 0.0 0.5 16.9 0.0 1.3 0.3 3.0 0.2 0.1 6.0 4.2 0.1 0.0 0.0 1.2 16.2 1.5 0.6 1.7 0.5 15.6 10.8 0.1 3.7 3.5 1.5 8.3 19.1 0.8 16.9 23.4 27.3 9.7 14.4 17.5 15.4 8.0 13.4 14.3 2.3 18.5 24.6 0.5 14.7 17.2 10.1 10.0 8.7 12.2 8.8 9.1 11.4 10.1 10.0 8.8 10.8 8.7 59.1 3.2 8.6 1.6 21.1 5.0 4.3 3.9 2.2 0.0 5.8 4.2 7.9 8.6 4.3 3.7 0.0 1.9 16.0 0.3 0.0 2.5 0.9 1.8 4.7 69.8 0.0 20.6 0.0 1.6 1.2 18.8 7.1 1.3 9.5 2.0 69.7 20.6 6.9 0.0 0.0 7.5 2.0 38.7 10.6 1.4 24.2 19.6 3.6 9.4 29.2 0.7 46.4 0.0 0.0 3.0 0.1 9.8 15.3 10.4 5.3 2.8 4.2 0.3 13.1 3.2 10.1 0.2 0.3 4.1 4.1 0.8 31.5 4.3 2.3 4.7 ARHGAP17 "FLJ10308, FLJ13219, NADRIN, RICH1, WBP15" ENSG00000140750 "Rho GTPase activating protein 17" Q68EM7 16 24919389-25015666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041703, HPA075891" Approved Supported "Plasma membrane,Cytosol" NA NA 21000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA041703: AB_10794304, HPA075891: " "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (8.11e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.42e-2)" "unprognostic (3.49e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (3.02e-2)" "unprognostic (6.62e-2)" "unprognostic (8.81e-3)" "unprognostic (4.99e-2)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (1.94e-1)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.76e-4)" 46.0 40.5 8.2 15.2 9.8 9.2 37.2 9.2 10.2 29.9 9.6 32.7 11.3 28.9 7.9 33.6 28.6 11.9 48.1 7.9 9.2 25.9 22.9 31.8 24.9 10.6 9.5 24.8 24.1 9.3 30.3 15.3 10.4 23.6 12.2 2.3 21.3 7.9 41.0 34.3 39.2 11.6 8.7 66.8 28.9 25.5 9.7 12.0 28.2 11.1 20.9 25.6 29.8 11.6 28.5 16.7 21.9 23.1 22.0 23.0 23.7 18.1 19.3 20.9 20.4 25.9 11.5 13.0 12.0 36.4 19.9 7.7 21.8 12.8 22.2 20.0 26.1 10.8 37.8 43.3 25.0 15.5 10.7 29.4 7.7 22.6 16.3 15.0 35.7 11.7 14.3 0.0 23.6 20.8 14.3 19.8 25.2 8.1 13.7 68.1 17.9 5.2 25.9 6.4 14.6 14.5 18.6 20.5 8.2 17.5 11.1 40.2 46.7 15.5 11.9 35.6 15.1 13.0 17.3 7.5 19.1 22.6 14.1 5.6 9.7 9.0 6.3 17.5 5.7 25.3 5.5 6.3 14.6 22.8 6.2 6.1 4.8 6.2 15.8 25.9 8.0 8.1 8.2 9.8 9.2 10.2 7.9 9.2 10.6 9.5 10.4 8.7 9.7 11.6 33.8 9.6 11.0 26.8 46.3 14.5 6.8 8.9 14.2 6.4 11.0 9.7 24.9 7.2 9.1 5.5 10.4 11.1 36.3 49.5 3.9 13.3 6.3 30.6 21.8 32.3 21.0 16.2 28.8 16.0 18.9 16.0 15.3 66.4 7.0 16.9 26.7 6.8 27.1 10.1 33.0 21.8 8.2 30.3 21.7 10.8 13.4 25.2 16.0 59.0 22.8 6.4 14.4 40.2 68.9 17.6 27.2 11.7 11.5 11.1 35.4 5.0 8.5 7.5 26.3 15.5 43.8 7.0 11.7 24.7 24.0 15.7 21.1 15.9 19.7 12.2 ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 440.8;Endothelial cells: 298.6;Prostatic glandular cells: 593.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A-431: 118.8;hTERT-HME1: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: AB_1844998" "unprognostic (2.49e-1)" "unprognostic (1.52e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (8.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (4.42e-1)" "unprognostic (2.36e-2)" "unprognostic (3.81e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (4.61e-3)" 32.9 3.7 7.0 2.8 5.5 0.1 30.3 22.5 8.0 8.8 7.3 9.4 2.1 7.4 5.3 4.5 10.2 6.5 19.2 4.6 5.5 23.7 16.8 27.1 4.9 6.8 6.1 10.2 7.4 6.5 6.2 17.4 7.1 11.2 3.2 14.9 12.1 7.0 11.6 14.7 6.4 5.6 6.4 21.7 10.4 5.8 8.6 3.0 22.8 12.7 2.8 8.0 9.3 5.1 118.8 4.8 7.0 0.1 26.7 57.5 24.5 38.6 62.9 31.0 45.1 13.7 5.4 0.0 85.2 76.5 36.3 24.8 0.2 27.4 63.9 0.1 4.1 0.4 6.6 7.6 2.7 0.0 0.0 11.7 5.4 23.7 100.9 36.4 88.0 0.1 0.0 0.0 32.1 4.7 2.2 0.1 9.0 0.6 82.1 1.4 5.6 0.0 82.7 10.8 0.1 1.5 24.1 20.5 2.0 26.5 5.6 0.4 84.2 20.0 26.2 29.7 32.3 0.1 0.1 0.2 3.7 0.0 0.9 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 7.0 5.5 22.5 8.0 4.6 5.5 6.8 6.1 7.1 6.4 8.6 5.1 440.8 51.3 18.4 26.4 2.9 23.5 239.2 31.7 4.6 16.0 87.3 46.1 26.0 31.5 39.6 130.6 18.8 29.5 2.0 0.9 54.8 83.5 94.1 36.9 11.4 298.6 0.0 3.2 11.3 17.2 102.6 63.6 20.9 106.2 3.8 13.8 177.1 56.1 3.0 92.5 24.1 1.0 6.1 13.6 17.9 24.4 24.5 6.2 26.6 208.9 2.5 94.2 0.0 2.0 3.5 55.7 0.1 21.8 0.1 593.9 0.1 78.1 12.5 81.2 190.7 58.2 127.8 80.3 116.5 1.7 17.2 14.1 4.1 11.1 1.6 146.9 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 ASB9 "DKFZP564L0862, FLJ20636, MGC4954" ENSG00000102048 "Ankyrin repeat and SOCS box containing 9" Q96DX5 X 15235288-15270467 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 16.8;liver: 17.4;lymphoid tissue: 11.7;pancreas: 9.5;testis: 25.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 41.1;Proximal tubular cells: 38.1;Spermatogonia: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 25.8;EFO-21: 20.1;PC-3: 53.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA003014, HPA003060, CAB004997" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "CAB004997: AB_426132, HPA003014: AB_1078226, HPA003060: AB_1078225" "unprognostic (8.26e-3)" "unprognostic (1.70e-1)" "unprognostic (8.82e-2)" "unprognostic (2.25e-3)" "unprognostic (1.31e-1)" "unprognostic (2.70e-2)" "unprognostic (6.44e-2)" "unprognostic (1.45e-2)" "unprognostic (2.39e-1)" "unprognostic (9.23e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (2.88e-1)" "unprognostic (2.27e-2)" "unprognostic (9.22e-2)" "unprognostic (1.27e-1)" "unprognostic (2.57e-1)" 2.3 0.8 0.7 0.4 0.6 2.4 1.5 0.9 1.0 2.3 0.6 1.7 1.6 1.3 0.8 1.5 2.2 1.9 2.5 0.6 0.5 16.8 17.4 3.5 0.9 1.0 0.6 0.6 9.5 0.6 0.5 3.1 0.8 1.0 2.3 0.1 3.8 0.8 0.5 1.8 1.0 2.3 0.6 11.7 4.0 25.8 0.7 4.1 2.2 1.4 1.2 1.4 0.8 0.7 1.5 25.8 0.2 2.4 0.0 1.1 0.7 0.6 2.7 2.9 1.1 5.8 0.1 0.3 20.1 0.9 14.1 7.5 0.0 1.2 1.9 5.4 0.6 6.2 12.6 12.5 0.0 0.0 0.0 6.6 0.2 0.2 0.1 0.3 9.4 1.9 0.1 5.9 1.7 1.8 5.4 0.1 12.2 3.6 53.5 0.1 11.1 5.8 8.0 4.2 2.6 2.6 0.7 1.4 9.0 1.3 0.1 0.7 8.1 0.1 1.8 1.3 3.9 0.4 5.1 0.2 0.8 0.0 14.2 0.5 0.6 0.0 0.0 0.0 0.7 0.0 0.1 0.0 1.6 0.1 1.2 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.7 0.6 0.9 1.0 0.6 0.5 1.0 0.6 0.8 0.6 0.7 0.7 10.7 0.0 0.0 0.0 1.1 1.9 1.1 0.7 2.2 0.0 0.8 0.9 0.5 12.8 1.0 0.0 0.0 0.1 0.1 0.9 41.1 1.1 2.4 1.2 0.3 11.1 10.7 7.2 0.1 2.0 0.1 1.2 2.6 0.3 1.3 3.4 20.0 12.6 4.7 0.0 0.3 0.3 2.0 4.6 4.4 8.0 1.8 3.3 16.0 1.0 0.3 0.0 0.0 0.0 0.1 0.9 0.5 0.7 0.0 0.6 0.0 38.1 4.8 0.0 0.0 0.0 0.6 1.6 126.5 2.4 3.1 0.1 0.3 5.7 1.6 0.6 ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase and isoaspartyl peptidase 1" Q7L266 11 62337448-62393412 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.7;cervix: 121.7;testis: 100.5" "Cell type enhanced" "Detected in many" "Early spermatids: 372.5;Endometrial ciliated cells: 414.6;Glandular and luminal cells: 437.1;Late spermatids: 597.6;Proximal tubular cells: 214.1;Spermatocytes: 534.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 277.9;eosinophil: 269.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 277.9" "Cell line enhanced" "Detected in many" "EFO-21: 85.2;HAP1: 83.9;SCLC-21H: 112.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029725, HPA055572, CAB070192" Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge" "CAB070192: AB_2665720, HPA029725: AB_10602328, HPA055572: AB_2682854" "unprognostic (1.14e-1)" "unprognostic (8.38e-3)" "prognostic favorable (6.14e-4)" "prognostic favorable (1.56e-5)" "unprognostic (5.35e-2)" "unprognostic (8.19e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.54e-2)" "unprognostic (2.71e-1)" "unprognostic (4.44e-1)" "prognostic favorable (4.32e-7)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.43e-3)" "unprognostic (1.40e-1)" 13.8 3.7 94.2 6.5 95.4 14.4 12.0 92.5 103.5 121.7 71.7 14.2 6.8 26.4 3.1 2.1 68.1 11.2 6.2 87.1 93.3 42.5 10.2 25.8 5.6 87.5 102.7 1.8 13.4 2.3 21.2 3.2 87.6 23.8 17.1 17.8 13.2 7.2 7.3 2.9 9.5 4.4 83.4 4.7 15.1 100.5 112.7 10.3 6.7 3.0 4.7 4.3 2.0 90.0 2.4 19.5 20.9 27.2 0.1 0.0 16.4 2.3 0.8 3.6 3.5 32.0 8.5 1.9 85.2 0.3 9.3 1.8 83.9 0.7 4.2 2.6 34.4 1.2 28.1 23.5 0.6 24.0 30.8 0.8 0.2 1.6 0.4 1.3 39.4 47.8 24.5 21.5 0.9 37.5 65.3 15.9 28.5 13.6 15.2 26.1 12.5 11.8 73.3 5.9 112.3 16.1 16.4 28.2 14.4 21.2 15.0 12.1 2.0 0.4 15.4 1.2 9.5 32.8 33.6 3.0 0.8 12.3 9.7 277.9 68.6 269.5 2.8 50.8 1.9 2.4 1.0 3.3 39.7 1.5 2.3 3.4 16.3 11.5 38.5 7.2 0.8 24.2 94.2 95.4 92.5 103.5 87.1 93.3 87.5 102.7 87.6 83.4 112.7 90.0 29.2 6.4 27.8 56.8 5.2 3.4 2.5 2.2 0.6 24.4 13.8 6.6 2.4 42.9 4.1 22.0 33.3 2.3 3.2 14.0 133.1 30.3 372.5 414.6 39.9 31.2 47.2 14.1 13.9 22.3 2.4 4.0 19.9 437.1 80.9 16.6 49.2 3.7 25.0 16.8 18.6 67.4 6.1 11.4 6.4 597.6 8.7 26.9 1.8 9.4 10.5 80.8 4.1 15.1 22.0 7.8 7.5 7.2 13.9 35.4 2.9 214.1 5.4 37.1 13.1 7.7 6.1 534.3 48.6 0.1 1.3 0.8 7.8 10.8 36.0 15.9 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 CARHSP1 "CRHSP-24, CSDC1" ENSG00000153048 "Calcium regulated heat stable protein 1" Q9Y2V2 16 8852942-8869012 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 422.7" "Group enriched" "Detected in all" 7 "Early spermatids: 2062.2;Late spermatids: 6999.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051911 Enhanced NA Yes 280000 "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA051911: AB_2681660" "unprognostic (4.08e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.15e-1)" "unprognostic (2.08e-3)" "unprognostic (8.57e-2)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (3.29e-1)" "unprognostic (2.61e-1)" "unprognostic (7.19e-3)" "unprognostic (1.76e-3)" "unprognostic (5.94e-2)" "unprognostic (1.10e-1)" "unprognostic (2.61e-1)" "prognostic favorable (7.24e-4)" 101.4 132.5 49.4 33.7 75.0 70.0 67.7 46.8 58.4 101.7 46.5 46.4 31.3 38.2 13.5 193.7 51.0 33.8 48.2 50.1 50.8 109.6 188.2 116.7 46.9 56.1 49.7 68.5 54.8 9.8 33.2 59.2 51.2 35.3 25.6 3.0 110.7 13.9 17.4 34.5 47.1 24.2 47.6 56.7 52.5 422.7 51.0 59.6 35.9 21.3 59.4 45.8 101.7 60.4 84.2 134.8 200.2 40.3 52.1 83.0 98.9 110.7 93.5 92.9 117.8 95.4 224.6 109.1 70.2 83.5 70.9 82.0 79.3 87.9 65.4 87.9 102.1 34.5 108.1 369.8 177.5 59.2 84.6 181.7 40.0 91.8 60.7 87.8 92.6 241.5 94.5 136.1 120.5 152.0 313.5 147.6 124.6 89.0 82.2 367.0 245.9 179.3 75.5 56.0 119.0 153.2 104.9 106.1 104.0 112.4 134.9 60.3 99.9 77.8 144.9 94.6 57.4 67.6 77.4 135.0 173.9 71.9 134.9 81.6 29.6 35.8 25.8 14.3 16.1 17.5 25.0 25.3 25.8 28.6 17.0 23.7 89.2 41.6 19.0 47.4 62.8 20.8 49.4 75.0 46.8 58.4 50.1 50.8 56.1 49.7 51.2 47.6 51.0 60.4 166.3 25.6 9.1 19.6 48.9 42.7 67.2 158.4 22.8 8.0 71.4 38.0 6.0 221.6 86.4 82.8 6.2 141.5 65.1 152.6 54.8 619.1 2062.2 101.9 82.0 145.3 144.9 147.5 4.4 241.8 312.6 86.4 42.8 114.4 39.3 118.0 128.8 323.5 70.5 11.8 5.9 107.7 91.6 62.4 55.3 6999.5 96.3 36.1 58.7 9.4 66.5 7.7 121.5 8.0 25.6 340.0 179.5 73.0 63.9 139.3 174.2 479.0 70.9 11.2 111.7 31.2 95.5 72.7 52.7 84.2 42.1 153.5 65.1 17.0 108.4 169.8 CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969366 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavorable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" 45.7 21.7 7.0 69.4 7.2 48.5 44.4 7.4 12.4 26.4 8.6 27.6 62.4 18.4 33.1 47.7 34.9 50.1 17.8 7.5 8.0 33.3 54.1 61.3 80.2 9.7 8.1 43.2 52.5 4.7 11.0 70.2 8.7 21.7 30.7 2.0 55.2 15.5 7.5 46.7 58.8 32.2 8.3 71.1 42.4 4.9 9.0 57.2 15.6 18.1 82.1 76.5 30.5 8.7 33.8 9.5 0.0 12.9 58.2 140.4 27.8 68.0 103.2 80.5 117.0 22.4 128.5 22.3 123.1 71.5 110.4 52.7 0.0 94.3 78.8 22.4 0.4 53.1 7.4 55.8 158.2 48.5 19.2 122.6 127.0 97.9 144.4 104.7 143.8 0.5 1.3 0.0 64.4 2.8 26.1 46.7 0.0 71.6 28.2 21.4 21.5 14.2 64.9 46.2 0.6 0.4 60.8 31.6 49.3 0.7 11.9 62.5 93.2 84.4 30.4 80.8 40.5 0.0 0.0 0.3 42.2 105.5 63.4 136.4 292.0 50.6 208.9 312.9 224.8 141.9 155.6 193.9 205.5 144.4 93.4 138.5 667.2 226.2 255.4 35.4 257.9 410.9 7.0 7.2 7.4 12.4 7.5 8.0 9.7 8.1 8.7 8.3 9.0 8.7 78.1 60.9 60.8 0.3 87.4 55.8 63.3 130.1 21.1 0.0 40.8 48.4 5.6 47.1 107.0 22.0 0.0 129.1 80.4 12.4 15.6 157.5 0.6 35.9 27.7 73.0 20.9 12.4 0.0 189.9 103.0 53.6 33.1 45.7 34.8 32.6 82.1 34.7 116.7 0.0 0.2 37.8 73.2 168.0 81.2 2.1 29.2 105.2 30.2 23.4 141.5 1.9 177.1 1.5 0.2 148.5 8.6 20.7 50.5 31.1 85.4 41.1 86.1 0.4 6.6 38.1 34.2 0.2 0.5 25.8 45.9 115.9 102.1 36.8 32.9 80.0 CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 113.7;Inhibitory neurons: 112.5;Oligodendrocyte precursor cells: 123.1;T-cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA018327: AB_1846097, HPA019880: AB_1846099" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.72e-2)" "unprognostic (2.38e-1)" "unprognostic (5.89e-3)" "unprognostic (2.80e-2)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.43e-2)" "unprognostic (8.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" 17.3 5.8 5.6 6.7 4.6 11.9 11.0 17.4 5.9 6.8 5.8 6.3 6.2 6.3 4.3 3.5 8.8 8.4 12.2 5.2 7.3 4.3 4.4 9.9 14.5 4.4 5.3 10.0 3.6 2.3 3.8 6.5 5.7 4.7 5.1 9.2 6.7 2.3 7.8 6.8 8.2 3.0 2.0 8.5 8.3 6.4 6.5 4.3 9.1 5.1 6.9 10.0 6.5 4.0 2.4 3.2 10.7 5.4 11.8 12.1 6.8 7.6 4.0 2.3 3.7 4.1 2.6 5.2 5.4 4.2 3.6 3.9 1.5 1.4 2.8 3.8 4.0 2.8 16.1 2.7 17.7 2.0 2.0 11.9 4.3 6.2 16.7 8.5 7.9 5.2 3.0 15.5 5.0 2.8 2.9 1.3 3.6 2.9 4.4 6.1 3.1 0.9 5.9 10.2 8.2 8.9 9.5 1.1 11.9 7.3 2.4 4.3 4.8 32.0 2.6 4.5 2.0 8.8 0.7 8.3 8.6 1.7 2.1 0.7 1.4 2.8 8.9 0.9 7.9 2.1 4.6 5.1 1.3 4.8 3.9 7.0 1.0 10.2 2.0 3.1 5.7 1.7 5.6 4.6 17.4 5.9 5.2 7.3 4.4 5.3 5.7 2.0 6.5 4.0 26.0 16.0 6.1 57.8 43.1 10.8 6.9 35.6 25.6 42.6 12.0 9.7 43.7 2.8 13.7 12.9 27.1 10.1 113.7 12.8 5.9 8.4 34.1 20.9 47.0 34.0 12.6 10.8 48.9 7.8 83.2 55.2 43.8 26.4 8.8 21.3 33.2 8.1 13.9 3.3 112.5 18.8 6.1 13.5 17.1 14.4 7.5 14.6 16.0 74.9 9.0 7.5 59.8 123.1 100.3 15.5 8.6 10.9 53.1 8.9 17.6 3.9 20.2 28.9 6.6 23.6 28.9 11.1 13.3 10.3 7.0 45.4 111.5 5.5 9.9 7.0 CBX2 "CDCA6, MGC10561" ENSG00000173894 "Chromobox 2" Q14781 17 79778148-79787983 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Sexual differentiation, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.3;testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 32.5;Granulosa cells: 10.4;Late spermatids: 39.1;Spermatogonia: 14.3" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 96.4;SK-BR-3: 134.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023083 Approved Supported Nucleoplasm NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA023083: AB_2671063" "unprognostic (1.37e-2)" "unprognostic (1.19e-1)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (1.49e-1)" "unprognostic (9.72e-2)" "unprognostic (2.25e-11)" "unprognostic (1.05e-1)" "unprognostic (7.77e-2)" "unprognostic (6.34e-3)" "unprognostic (1.86e-3)" "unprognostic (1.66e-1)" "unprognostic (1.25e-8)" "unprognostic (1.34e-1)" "unprognostic (3.33e-2)" "unprognostic (2.37e-3)" "unprognostic (2.07e-1)" 1.4 0.3 1.1 0.7 0.9 2.2 1.2 0.8 0.9 1.3 0.5 0.5 0.4 1.2 1.8 4.2 1.0 0.6 2.3 0.8 0.7 1.6 0.4 1.2 1.3 1.0 0.9 2.1 1.3 0.5 0.2 2.2 1.1 0.6 0.2 0.5 0.9 0.5 0.7 2.1 0.6 0.7 0.8 1.6 0.5 12.8 1.0 7.3 0.5 1.1 1.3 1.0 1.6 1.0 7.5 20.5 37.0 67.4 0.4 0.5 13.2 2.7 1.2 1.3 2.4 21.2 1.7 29.7 5.8 0.3 4.7 3.8 43.0 1.2 0.9 4.3 23.3 1.5 24.0 14.2 1.4 9.0 6.1 0.7 2.6 0.7 1.7 1.6 7.5 31.3 20.8 2.3 1.4 31.3 47.3 22.1 36.8 10.3 23.4 96.4 27.7 18.0 1.5 10.5 45.1 69.8 11.7 134.7 8.0 17.6 24.5 13.4 5.4 13.1 38.4 4.0 5.3 8.7 4.8 18.3 0.5 24.1 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.8 0.9 0.8 0.7 1.0 0.9 1.1 0.8 1.0 1.0 5.3 0.0 0.0 0.3 0.1 1.0 0.3 0.4 0.0 1.0 0.6 1.8 2.5 0.0 0.3 1.8 2.1 0.4 2.9 0.4 1.9 3.6 32.5 0.9 1.8 8.6 0.0 5.9 0.1 0.9 1.4 0.8 1.1 1.8 0.0 10.4 3.6 1.1 1.2 0.0 0.0 0.8 0.0 0.6 0.9 39.1 0.6 0.5 3.6 0.0 0.8 4.3 0.0 0.0 0.3 1.1 0.0 0.7 0.5 0.7 0.0 0.8 0.1 0.4 0.0 0.3 1.0 1.6 14.3 4.1 1.4 0.3 1.2 0.9 0.5 0.9 CCDC178 "C18orf34, FLJ44050" ENSG00000166960 "Coiled-coil domain containing 178" Q5BJE1 18 32937402-33441101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.9;testis: 15.2" "Cell type enhanced" "Detected in some" "Adipocytes: 29.2;Early spermatids: 89.0;Late spermatids: 76.8;Spermatocytes: 49.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "HUVEC TERT2: 5.1;U-87 MG: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (9.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (2.58e-3)" "unprognostic (2.92e-1)" "unprognostic (5.95e-4)" "unprognostic (4.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.94e-4)" "unprognostic (2.86e-1)" "unprognostic (1.42e-3)" "unprognostic (9.03e-3)" 10.9 0.3 0.2 0.2 0.3 0.0 7.8 0.0 0.4 2.7 0.1 0.8 0.5 1.3 2.2 0.6 1.5 2.5 0.5 0.2 0.3 2.8 0.1 0.7 0.2 0.4 0.6 4.0 0.1 0.0 0.6 0.0 0.2 3.5 0.5 0.1 0.5 2.0 0.3 0.7 0.6 1.5 0.4 7.6 0.6 15.2 0.1 0.1 0.8 0.0 0.6 2.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.3 0.4 0.6 0.2 0.4 0.1 0.2 29.2 0.0 0.0 0.3 0.0 0.4 0.4 0.0 2.2 0.0 0.1 0.4 0.3 0.0 0.0 1.8 0.0 0.0 0.1 0.0 9.8 0.0 89.0 0.6 0.3 12.8 0.0 0.0 7.9 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 76.8 1.8 0.2 0.0 2.8 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.7 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 49.4 16.3 0.1 0.3 0.0 0.0 6.1 0.0 0.0 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 141.6" "Cell type enriched" "Detected in some" 5 "Theca cells: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.2;HUVEC TERT2: 9.0;NTERA-2: 4.6;RH-30: 3.2;SCLC-21H: 7.7;TIME: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" 15.9 5.4 7.2 1.6 7.3 0.0 15.0 9.5 6.8 8.7 4.2 4.6 1.3 8.9 0.6 3.7 7.7 2.5 23.2 6.1 5.8 13.3 2.2 11.8 1.5 6.8 6.4 3.6 2.6 1.4 4.1 7.8 7.0 5.8 1.1 0.4 3.4 1.8 4.8 3.9 5.4 3.3 6.1 141.6 4.2 1.6 7.3 0.8 10.2 4.8 0.9 6.4 6.3 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 9.0 0.9 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.1 0.0 0.6 3.2 0.1 0.0 0.0 7.7 0.9 0.2 0.0 0.0 1.1 2.5 0.0 4.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 7.3 9.5 6.8 6.1 5.8 6.8 6.4 7.0 6.1 7.3 5.2 45.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.5 0.6 4.6 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.2 32.1 0.0 0.0 2.9 0.2 0.0 1.0 0.0 0.2 0.0 4.3 24.3 0.0 0.0 3.3 2.4 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.8 0.3 0.6 0.1 0.3 0.0 0.1 248.7 0.0 0.1 CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1533.6" "Cell type enhanced" "Detected in many" "Adipocytes: 3219.2;Cardiomyocytes: 623.1;Hofbauer cells: 1369.8;Sertoli cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 962.6;intermediate monocyte: 270.6;myeloid DC: 507.1" "Group enriched" "Detected in all" 46 "dendritic cells: 507.1;monocytes: 962.6" "Group enriched" "Detected in some" 4 "ASC diff: 322.6;HEL: 158.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 16.9" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" 1533.6 24.6 3.4 51.7 2.5 148.2 540.4 1.6 2.0 11.6 2.7 40.5 113.6 8.7 38.2 19.6 40.5 84.0 540.9 2.6 6.9 7.0 80.8 131.2 18.8 22.0 21.2 4.0 31.2 25.0 2.0 413.3 15.7 5.0 40.9 0.3 31.9 8.6 248.5 28.6 119.7 39.4 14.0 309.9 31.2 7.7 24.0 22.1 69.1 381.6 7.2 22.2 13.4 3.9 0.0 0.0 1.0 0.2 322.6 3.3 0.7 0.9 10.7 0.1 0.1 0.0 0.0 0.1 0.6 1.4 0.3 0.1 4.3 0.5 0.1 0.6 0.4 158.1 0.5 25.7 0.2 0.1 0.1 31.0 12.6 0.1 0.2 7.7 0.9 0.0 5.8 0.0 1.8 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.5 0.5 0.1 0.9 1.3 0.8 0.6 0.3 2.7 11.1 19.3 0.4 0.5 0.5 0.6 0.3 0.2 0.8 0.4 0.1 54.3 41.8 12.3 962.6 3.7 1.9 270.6 2.1 3.6 0.6 0.6 507.1 0.5 0.8 0.4 15.8 5.9 72.0 128.3 1.5 692.4 3.4 2.5 1.6 2.0 2.6 6.9 22.0 21.2 15.7 14.0 24.0 3.9 3219.2 6.4 63.1 0.0 7.9 7.4 0.2 3.0 0.6 0.2 189.9 24.8 623.1 4.3 9.8 7.3 0.0 10.1 55.0 0.0 0.0 0.2 11.7 5.0 5.9 303.3 0.0 419.5 6.3 0.0 11.1 69.6 1.1 38.4 15.2 0.6 406.2 9.0 1369.8 0.0 2.2 0.6 8.2 153.7 67.3 3.9 0.6 159.6 16.0 17.8 255.2 0.0 7.2 0.5 1.3 0.1 0.0 0.0 4.2 0.8 9.9 0.4 1.2 0.3 696.8 33.1 452.1 4.6 0.7 0.8 4.7 18.3 5.9 1.9 0.2 0.3 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 592.5;Muller glia cells: 147.8;Proximal tubular cells: 223.6" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 106.1;Hep G2: 179.8;HSkMC: 67.4;RPTEC TERT1: 190.6" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 45.1 50.2 8.1 12.6 8.2 0.1 17.4 7.7 13.2 36.8 10.4 7.4 38.0 39.2 80.3 9.3 74.0 73.0 25.0 8.3 9.6 224.9 1098.8 50.7 8.9 15.6 10.2 32.1 26.0 3.1 8.4 24.1 10.7 8.3 6.4 53.0 15.0 26.7 3.9 2.7 22.3 24.3 10.5 33.1 14.4 8.8 9.2 2.3 14.5 4.6 7.5 34.1 8.3 10.6 0.0 0.6 0.0 0.3 0.0 0.2 0.1 1.5 1.4 0.1 0.2 0.0 106.1 0.0 32.9 0.0 0.5 0.0 0.0 0.0 0.0 34.8 0.7 0.0 0.4 179.8 6.2 0.3 0.0 67.4 0.0 0.1 0.0 3.6 4.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 190.6 0.5 0.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.0 0.1 18.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 8.2 7.7 13.2 8.3 9.6 15.6 10.2 10.7 10.5 9.2 10.6 48.1 12.8 50.9 3.6 4.0 1.0 12.2 15.2 0.6 3.4 2.1 5.6 2.3 108.7 36.2 64.4 2.1 0.1 0.3 1.7 31.3 69.3 0.2 34.1 46.4 57.7 0.0 2.7 0.3 30.9 0.2 34.3 8.2 33.6 3.8 72.1 55.0 592.5 0.7 1.7 0.2 1.9 0.0 16.7 1.5 0.8 16.8 2.0 0.0 4.7 1.6 147.8 0.0 0.0 0.3 30.8 2.4 0.0 0.0 3.8 17.0 223.6 8.4 7.3 0.0 1.3 9.4 1.6 0.5 1.9 1.1 0.3 3.4 18.5 4.1 12.6 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 27.5 18.6 10.3 18.5 9.8 23.0 21.7 9.0 11.8 19.5 14.4 7.7 6.0 17.3 9.5 10.8 14.9 22.7 20.1 9.2 10.3 13.7 10.0 23.6 11.6 14.2 13.8 19.7 7.3 7.4 8.5 46.7 11.9 14.4 8.2 7.0 10.1 11.4 6.5 15.0 7.7 20.0 11.5 13.9 10.4 8.7 12.5 10.5 10.0 7.4 10.3 34.8 14.0 9.8 9.1 11.2 36.8 18.7 18.9 25.0 24.5 21.8 19.2 25.8 26.2 9.7 7.1 22.0 12.7 36.3 16.8 24.7 24.5 27.7 28.2 24.6 12.4 43.4 12.2 11.4 23.3 66.9 42.9 23.2 22.8 22.3 20.1 29.3 30.8 9.7 16.2 216.3 19.7 7.9 9.2 46.3 42.5 17.7 7.9 20.6 36.9 32.8 18.1 17.7 6.4 34.6 23.0 11.1 40.8 29.8 12.6 81.6 26.2 41.9 24.1 20.0 46.5 38.2 94.5 12.7 32.5 62.2 32.0 0.0 1.3 2.9 1.5 0.8 1.7 0.9 0.9 1.6 0.8 1.0 0.5 1.0 4.9 0.7 0.9 0.5 1.8 0.6 10.3 9.8 9.0 11.8 9.2 10.3 14.2 13.8 11.9 11.5 12.5 9.8 55.0 0.0 15.7 27.7 11.4 57.9 20.7 10.1 20.5 10.7 41.9 29.8 9.3 5.7 9.4 16.5 6.2 6.1 14.6 1.6 1.9 5.3 1.2 10.0 33.4 45.8 3.0 12.0 34.2 2.2 28.8 40.0 5.1 13.8 25.9 51.9 60.0 5.4 16.6 38.7 36.1 3.6 10.2 17.8 37.1 2.5 55.0 41.2 26.6 59.0 10.2 9.2 10.3 21.1 24.2 5.5 2.5 47.0 9.3 19.3 1.2 2.4 8.1 7.5 46.0 47.9 53.5 3.9 7.5 10.5 62.5 13.8 15.2 23.0 3.9 10.2 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 115.5;Microglial cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 66.8;THP-1: 38.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038600 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" 12.0 8.3 7.0 5.4 7.6 4.6 9.6 3.1 11.5 7.8 9.2 8.1 3.3 5.1 3.5 5.4 5.0 9.0 12.2 10.1 8.9 11.2 15.5 10.1 5.4 5.0 6.5 5.7 3.2 2.5 3.3 12.0 4.6 3.7 10.2 6.0 3.2 8.9 2.9 6.1 4.6 9.1 8.8 10.6 3.7 5.8 8.0 3.1 7.8 5.3 3.2 10.1 5.3 5.5 3.1 18.7 1.3 18.5 17.0 14.3 8.6 1.6 0.1 0.0 0.0 9.4 18.2 0.0 26.3 12.7 6.8 1.0 10.8 5.6 0.0 0.0 11.3 9.9 26.3 2.2 11.3 0.0 7.8 6.7 14.2 4.2 14.9 12.9 14.3 0.0 6.0 0.0 0.0 0.0 0.0 0.1 13.8 11.5 19.0 0.0 0.0 4.3 66.8 0.5 0.0 0.5 26.0 4.7 14.1 18.8 2.3 38.8 13.6 0.0 12.7 21.6 0.1 6.5 19.3 0.2 17.2 17.8 11.0 2.7 12.0 0.0 1.6 9.4 0.3 0.2 2.1 1.8 7.7 0.6 0.9 1.5 0.7 4.5 6.3 2.5 2.1 2.5 7.0 7.6 3.1 11.5 10.1 8.9 5.0 6.5 4.6 8.8 8.0 5.5 68.8 12.8 8.2 66.3 1.6 31.1 5.9 40.8 19.9 2.1 0.6 6.5 20.3 15.7 23.3 12.9 0.0 29.2 6.9 35.8 15.6 7.6 68.9 2.7 9.4 55.9 11.5 7.4 115.5 4.9 27.2 27.1 0.0 3.0 3.8 18.5 36.0 16.5 25.7 0.0 36.3 9.1 6.1 34.1 42.4 14.5 9.6 19.4 46.2 77.8 19.8 36.4 2.1 25.6 2.9 3.6 51.3 8.2 3.3 7.4 0.0 20.9 17.0 2.7 0.0 24.5 16.9 2.7 2.1 6.1 11.2 7.8 4.3 8.6 8.9 3.5 CSRP2 "CRP2, LMO5, SmLIM" ENSG00000175183 "Cysteine and glycine rich protein 2" Q16527 12 76858709-76879023 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.3;Muller glia cells: 625.9;Smooth muscle cells: 268.4;Squamous epithelial cells: 271.2" "Cancer enhanced" "Detected in all" "glioma: 24.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 336.2;BEWO: 177.9;fHDF/TERT166: 184.9;HEK 293: 186.4;NTERA-2: 181.4;WM-115: 188.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 63000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA045617: AB_2679391" "unprognostic (9.06e-2)" "unprognostic (4.32e-2)" "unprognostic (5.18e-3)" "unprognostic (1.58e-1)" "unprognostic (5.40e-1)" "unprognostic (2.79e-3)" "unprognostic (2.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.18e-1)" "unprognostic (3.54e-2)" "unprognostic (2.67e-1)" "prognostic favorable (8.52e-4)" "prognostic unfavorable (4.48e-5)" "unprognostic (3.55e-2)" "unprognostic (4.41e-1)" "unprognostic (3.08e-1)" "unprognostic (3.45e-1)" 68.9 8.2 52.7 32.6 55.5 0.3 52.2 56.9 70.0 77.4 54.4 34.2 17.2 54.3 27.1 98.0 55.8 61.6 37.4 51.6 62.6 88.3 45.2 57.7 27.8 55.5 56.6 30.1 16.6 11.6 28.7 84.0 57.7 48.5 16.3 64.9 29.9 15.9 15.3 24.1 39.0 37.2 55.5 19.4 45.8 23.7 61.4 26.9 50.0 34.4 37.5 47.4 62.6 61.4 26.0 23.0 336.2 67.7 15.0 3.3 177.9 43.7 52.5 39.3 108.2 15.3 1.1 0.3 17.5 184.9 30.9 31.4 75.3 44.5 63.0 3.2 186.4 0.3 46.4 14.9 3.7 0.0 0.7 18.0 29.5 31.8 5.6 67.8 8.1 12.9 1.2 1.0 68.8 8.3 3.8 0.3 181.4 1.6 39.1 39.5 90.9 0.3 130.3 61.7 17.4 111.8 74.3 2.7 17.9 92.5 0.1 0.8 1.9 34.3 44.4 8.5 32.6 2.2 1.9 3.7 10.5 0.6 188.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 52.7 55.5 56.9 70.0 51.6 62.6 55.5 56.6 57.7 55.5 61.4 61.4 93.8 0.0 1.7 6.2 1.8 78.5 105.5 24.3 133.7 16.7 12.7 57.0 14.4 20.0 8.5 14.7 10.4 275.3 2.7 0.8 215.2 28.5 35.3 107.1 16.1 119.1 0.0 0.0 4.7 4.4 156.7 116.6 7.7 82.4 0.0 61.7 13.2 25.7 28.8 0.0 2.1 2.5 2.0 1.0 43.7 21.0 3.7 5.3 49.8 13.1 76.1 625.9 0.0 2.5 0.6 5.5 1.4 9.1 8.1 72.7 0.4 140.8 2.7 19.4 210.4 138.0 268.4 81.2 44.8 271.2 61.9 117.9 5.9 25.1 3.8 55.0 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 DDX41 "ABS, MGC8828" ENSG00000183258 "DEAD-box helicase 41" Q9UJV9 5 177511577-177516961 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017911, HPA048803" Supported Supported Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA017911: AB_1847558, HPA048803: AB_2680527" "unprognostic (2.52e-1)" "unprognostic (1.51e-1)" "unprognostic (7.57e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-1)" "unprognostic (2.61e-2)" "unprognostic (4.21e-3)" "unprognostic (2.60e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (4.47e-2)" "prognostic unfavorable (2.21e-6)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (1.75e-1)" 26.5 29.0 15.1 28.7 16.1 22.3 25.4 13.1 21.9 26.1 13.7 26.5 24.8 25.2 16.8 33.7 30.6 18.3 18.9 17.8 14.2 26.8 27.1 24.5 24.7 15.8 13.7 28.6 23.5 31.2 18.0 22.8 16.0 22.3 19.3 14.6 28.7 19.1 43.4 35.0 28.7 20.1 12.8 26.7 26.7 17.9 16.2 24.3 29.0 20.3 25.0 24.8 27.6 16.4 62.1 71.4 42.4 44.9 43.4 45.2 125.1 58.4 35.1 47.1 36.1 107.7 61.3 67.2 83.3 57.6 67.6 47.8 57.2 128.5 33.2 175.4 68.0 90.5 70.8 66.5 52.5 89.3 82.3 48.7 47.0 45.3 59.0 43.5 53.4 68.1 72.3 50.0 55.6 135.5 80.6 45.9 62.0 59.0 61.3 72.7 48.1 86.2 50.5 78.8 45.0 41.9 64.6 83.2 56.5 27.1 54.6 110.2 51.3 74.4 42.8 43.6 87.6 49.6 75.9 120.1 81.3 100.1 47.0 14.3 31.4 22.3 18.3 28.5 23.5 17.0 18.3 16.8 27.2 14.4 14.6 18.8 9.2 25.8 31.4 11.2 18.8 25.6 15.1 16.1 13.1 21.9 17.8 14.2 15.8 13.7 16.0 12.8 16.2 16.4 17.0 25.6 17.8 7.8 20.6 21.0 22.9 37.9 18.2 16.9 17.5 16.5 9.0 25.8 24.3 9.2 2.1 46.6 22.9 22.9 41.1 42.1 11.2 16.1 16.5 22.3 11.4 25.2 6.0 39.6 63.2 17.6 17.3 19.2 29.8 21.3 16.1 18.0 48.8 8.4 6.4 27.0 18.3 23.5 15.4 22.9 14.9 22.2 12.4 4.7 34.6 23.9 20.6 5.0 3.9 33.5 23.9 21.1 23.2 19.0 29.5 40.1 20.5 10.3 13.1 14.5 29.0 24.5 26.7 26.2 20.3 37.5 19.0 25.6 31.0 22.7 DEPP1 "C10orf10, DEPP, FIG, Fseg" ENSG00000165507 "DEPP1 autophagy regulator" Q9NTK1 10 44970981-44978809 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 889.5;breast: 697.2" "Cell type enhanced" "Detected in many" "Adipocytes: 192.0;Ductal cells: 146.3;Exocrine glandular cells: 113.0;Glandular and luminal cells: 87.1;Syncytiotrophoblasts: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 143.2;HDLM-2: 106.7;HHSteC: 258.2;HSkMC: 201.6;HUVEC TERT2: 165.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013687, HPA037818, HPA037819" Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria Vesicles "CAB013687: , HPA037818: , HPA037819: AB_2675685" "unprognostic (3.99e-2)" "unprognostic (4.69e-2)" "unprognostic (5.57e-2)" "unprognostic (3.55e-1)" "unprognostic (1.88e-2)" "unprognostic (5.66e-3)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (4.25e-1)" "unprognostic (5.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.89e-2)" "prognostic unfavorable (2.29e-6)" "unprognostic (2.30e-3)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.74e-1)" 889.5 48.4 62.3 19.4 71.4 4.5 697.2 59.5 71.8 153.0 50.3 145.7 16.7 168.5 16.5 65.7 334.2 68.5 260.6 55.5 71.9 95.4 131.6 508.6 63.0 175.9 72.3 297.8 349.7 23.0 85.2 76.5 93.4 82.6 12.0 28.2 119.7 22.8 165.8 165.0 94.8 68.8 101.6 32.8 104.6 19.3 87.4 25.2 200.5 52.2 47.6 177.6 139.1 90.6 30.2 0.2 0.5 0.4 143.2 69.5 7.4 0.2 10.2 0.4 1.8 1.1 11.2 0.0 1.6 13.5 7.1 1.2 1.2 9.1 0.7 106.7 4.0 0.1 0.1 11.0 258.2 0.1 0.1 201.6 0.4 0.1 1.4 24.9 165.0 0.0 0.2 63.2 0.6 0.0 0.1 1.7 0.2 0.6 0.9 5.1 1.7 25.7 0.5 10.9 5.6 0.3 0.0 1.3 5.8 17.0 0.2 7.0 1.6 7.8 5.6 0.5 7.3 1.7 2.8 0.4 44.2 2.6 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.4 62.3 71.4 59.5 71.8 55.5 71.9 175.9 72.3 93.4 101.6 87.4 90.6 192.0 0.0 24.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 47.0 27.8 0.0 0.0 6.2 31.3 0.0 53.8 1.4 0.0 37.2 146.3 0.0 61.3 33.2 60.0 0.0 0.0 0.0 113.0 14.7 79.3 0.0 87.1 0.0 8.4 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 65.0 0.0 0.0 0.5 0.0 0.0 25.5 5.8 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 300.2 1.8 0.8 0.0 0.0 DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Distal enterocytes: 24.2;Endothelial cells: 48.6;Hepatic stellate cells: 30.4;Intestinal goblet cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BJ hTERT+: 59.4;HUVEC TERT2: 15.7;SCLC-21H: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" 25.2 2.6 6.9 2.9 6.1 0.3 21.2 6.5 7.0 8.0 4.9 7.6 4.0 8.8 1.0 3.7 7.6 3.7 23.8 5.8 6.0 10.0 3.5 22.5 5.0 7.1 6.5 4.1 2.9 2.9 5.6 19.8 7.5 7.9 3.0 0.9 4.3 2.7 10.0 5.5 6.8 4.2 6.6 4.6 4.8 1.5 8.4 5.0 15.4 10.6 1.7 8.7 7.6 6.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.9 59.4 0.2 0.3 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 0.4 1.1 0.1 0.1 0.0 0.6 0.0 0.9 0.0 1.4 0.5 1.6 0.0 0.1 32.5 0.0 0.3 0.7 0.0 0.0 0.0 3.5 0.9 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 6.1 6.5 7.0 5.8 6.0 7.1 6.5 7.5 6.6 8.4 6.2 70.7 0.0 2.7 0.0 1.7 1.3 0.2 0.2 4.0 4.9 1.6 2.8 3.2 1.5 0.9 0.0 0.0 1.5 0.2 24.2 0.0 0.2 0.2 1.9 0.7 48.6 17.4 0.0 0.9 0.2 0.6 3.1 13.3 2.6 2.5 0.0 30.4 0.1 0.2 0.0 0.6 36.3 6.1 1.6 0.8 0.3 0.0 0.8 1.8 11.2 0.0 0.2 0.0 0.5 0.5 0.2 16.7 0.0 3.5 2.3 9.2 0.0 0.2 1.4 0.0 0.9 3.8 0.8 2.0 1.0 1.6 1.9 0.4 0.4 12.0 0.6 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 ELFN1 PPP1R28 ENSG00000225968 "Extracellular leucine rich repeat and fibronectin type III domain containing 1" P0C7U0 7 1688119-1747954 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2;liver: 14.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Endothelial cells: 5.7;Hepatic stellate cells: 7.1;Hepatocytes: 13.5;Inhibitory neurons: 19.2;Rod photoreceptor cells: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 31.2;U-138 MG: 18.5;U-2 OS: 27.0;U-2197: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066382 Approved "Nucleoplasm,Cell Junctions" NA NA 43000 "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "HPA066382: AB_2732744" "unprognostic (8.45e-2)" "unprognostic (3.39e-3)" "unprognostic (6.54e-4)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "prognostic favorable (9.68e-4)" "unprognostic (4.60e-3)" "unprognostic (1.63e-3)" "unprognostic (6.60e-2)" "unprognostic (4.14e-3)" "unprognostic (1.11e-2)" "unprognostic (2.31e-2)" "unprognostic (7.47e-3)" "unprognostic (8.63e-2)" "unprognostic (2.78e-1)" "unprognostic (4.07e-1)" 3.1 0.4 1.5 0.3 2.5 0.0 1.5 1.0 3.4 4.2 0.0 0.6 0.1 2.9 0.1 0.5 1.5 0.4 4.6 1.0 4.4 3.9 14.5 0.6 0.1 3.2 4.6 0.4 0.6 0.1 0.8 0.4 3.2 1.0 0.0 3.0 0.4 0.1 0.7 1.0 0.8 0.2 7.2 1.1 0.6 0.8 2.6 0.7 0.8 0.4 0.0 0.6 1.7 0.8 0.3 0.0 4.6 9.7 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.1 0.5 0.0 4.6 2.1 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 5.7 0.0 4.7 1.9 0.0 1.1 31.2 0.0 3.1 0.0 0.0 4.3 2.0 0.3 0.2 0.0 0.5 0.1 0.3 0.1 18.5 27.0 32.1 0.0 0.0 0.4 8.3 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.5 1.0 3.4 1.0 4.4 3.2 4.6 3.2 7.2 2.6 0.8 4.8 0.0 0.6 0.0 0.0 0.1 0.3 0.3 2.8 1.3 0.1 0.3 1.8 0.0 0.0 0.0 6.2 0.0 0.0 0.0 3.9 0.1 0.1 0.3 2.0 5.7 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.1 0.0 0.0 7.1 13.5 0.1 0.0 19.2 0.0 0.0 0.6 0.7 0.1 0.9 0.1 1.8 1.0 0.0 0.9 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.8 0.0 0.0 0.9 0.0 2.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 64.3;Oligodendrocyte precursor cells: 164.4;Oligodendrocytes: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 30.1;HeLa: 36.5;RT4: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Nucleoplasm "HPA036580: AB_10669908" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.92e-3)" "unprognostic (3.64e-2)" "unprognostic (4.73e-2)" "unprognostic (5.59e-3)" "unprognostic (4.40e-2)" "unprognostic (8.38e-2)" "unprognostic (1.90e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.65e-5)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" 8.7 4.5 4.8 3.2 5.7 3.6 5.3 4.1 4.8 4.1 9.0 4.0 2.6 4.3 12.7 10.1 7.4 13.8 9.2 6.0 5.1 11.7 3.3 7.7 3.3 5.7 4.6 5.7 4.9 8.0 0.5 9.3 4.8 5.8 4.8 16.0 7.2 5.4 4.2 8.8 3.4 2.7 4.9 4.7 5.6 6.1 4.8 3.6 13.5 4.2 3.6 5.1 2.3 4.8 0.8 5.5 14.3 1.5 0.0 0.0 2.9 2.1 0.0 0.0 0.0 3.0 12.3 6.2 30.1 0.0 0.8 7.4 1.1 6.9 0.0 1.0 5.0 9.8 36.5 2.0 0.1 2.6 3.1 0.0 3.0 0.0 0.0 1.6 9.2 1.7 1.9 5.6 0.0 1.8 4.6 3.5 2.7 1.2 1.1 2.3 10.7 1.3 8.4 21.6 11.8 6.1 10.7 5.2 4.5 9.8 15.9 1.4 15.7 0.7 2.4 1.9 4.4 5.6 1.3 4.6 1.4 5.2 0.8 0.5 0.2 0.1 2.0 0.3 1.1 1.4 0.6 0.6 0.2 1.6 0.9 1.8 0.2 0.1 0.5 0.1 0.6 0.5 4.8 5.7 4.1 4.8 6.0 5.1 5.7 4.6 4.8 4.9 4.8 4.8 55.9 28.9 7.7 17.3 4.7 6.0 16.8 11.2 13.6 5.0 11.2 4.7 8.3 64.3 24.2 14.7 4.2 7.4 4.5 8.5 11.7 15.0 20.8 19.7 3.1 35.2 1.2 2.1 28.6 7.5 0.7 8.4 7.1 17.1 8.8 11.9 34.6 1.7 2.7 1.7 31.8 6.3 16.2 4.6 2.1 23.0 1.8 1.8 3.6 56.2 3.2 8.2 14.4 164.4 65.4 14.1 10.9 1.9 6.5 13.7 1.9 30.4 39.5 32.1 0.0 8.7 6.0 1.8 9.1 16.0 8.1 2.5 3.7 2.2 7.5 19.1 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 ERICH1 ENSG00000104714 "Glutamate rich 1" Q86X53 8 614746-738106 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003725 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA003725: AB_1853023" "unprognostic (7.19e-2)" "unprognostic (1.38e-2)" "unprognostic (7.73e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-2)" "unprognostic (1.02e-1)" "unprognostic (7.51e-3)" "unprognostic (1.55e-1)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (8.45e-2)" "unprognostic (5.11e-2)" "unprognostic (1.27e-1)" "unprognostic (8.63e-2)" "unprognostic (3.07e-1)" "unprognostic (1.42e-1)" 15.9 8.7 7.3 17.2 6.5 23.0 13.7 6.4 8.2 10.7 8.3 11.0 8.4 10.1 6.6 10.4 10.5 9.1 10.7 6.9 7.1 22.5 11.6 14.6 21.1 9.0 7.1 11.6 9.0 7.9 11.5 10.1 8.4 9.1 7.2 5.1 9.8 5.8 10.8 13.0 12.4 7.9 6.0 15.3 10.5 8.0 8.4 11.8 13.2 5.5 10.7 12.7 11.6 7.1 15.8 22.2 11.7 14.0 12.4 15.0 24.3 14.9 7.9 13.3 14.6 14.4 9.9 36.0 6.9 12.5 25.3 26.0 21.7 22.9 9.4 15.7 28.1 25.1 15.1 20.8 13.9 15.5 22.6 17.4 14.5 10.1 13.0 13.7 14.7 31.2 26.3 20.2 13.5 13.2 30.0 27.5 18.6 17.6 9.9 27.0 7.6 25.0 14.9 28.7 5.4 15.0 10.9 13.8 20.2 19.2 5.8 18.4 23.7 9.7 4.6 0.6 16.2 13.1 36.7 38.9 19.9 24.6 10.5 24.7 33.0 12.5 8.4 32.3 7.5 17.9 9.7 8.4 17.1 20.1 8.1 7.1 30.0 12.3 29.8 12.7 7.5 10.4 7.3 6.5 6.4 8.2 6.9 7.1 9.0 7.1 8.4 6.0 8.4 7.1 71.0 44.8 36.1 17.9 75.3 36.6 47.0 47.9 32.5 23.3 32.6 32.5 23.0 27.1 31.2 33.1 12.5 62.0 55.4 49.2 109.5 38.4 16.1 35.9 52.2 65.8 19.7 43.9 24.4 36.6 60.4 40.7 66.8 57.4 41.1 48.3 62.4 31.9 41.9 48.8 21.0 50.4 32.6 70.9 68.0 9.2 60.3 69.9 35.6 23.4 126.9 18.2 78.2 11.1 22.5 55.4 54.3 40.6 34.6 51.5 33.3 58.9 26.9 22.1 39.5 33.6 35.6 48.5 58.4 23.2 40.9 54.0 68.3 27.0 39.8 37.0 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 F8 "DXS1253E, F8C, FVIII, HEMA" ENSG00000185010 "Coagulation factor VIII" P00451 X 154835788-155026940 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Hemophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.2" "Group enriched" "Detected in many" 10 "Adipocytes: 118.6;Endothelial cells: 120.4;Hepatic stellate cells: 371.2" "Cancer enhanced" "Detected in all" "renal cancer: 7.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB018777 Enhanced "Secreted to blood" NA NA 25000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB018777: AB_640320" "unprognostic (2.09e-1)" "unprognostic (5.66e-4)" "unprognostic (4.94e-2)" "unprognostic (8.32e-5)" "unprognostic (1.26e-1)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" "unprognostic (8.27e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (5.58e-2)" "unprognostic (1.24e-2)" "unprognostic (2.16e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (4.44e-2)" 29.4 15.2 7.8 2.5 8.6 2.1 19.3 7.4 11.2 7.5 9.9 9.6 2.9 10.9 9.1 4.0 7.9 5.0 53.2 8.2 8.5 14.1 20.1 16.7 4.7 8.6 8.4 14.5 11.6 5.6 6.4 3.3 8.6 9.0 3.8 6.2 4.7 7.5 20.6 3.6 5.0 6.3 7.8 17.9 5.7 6.1 8.9 3.2 10.9 28.1 3.7 8.1 3.7 7.8 6.1 4.5 0.9 2.1 6.5 10.1 0.7 2.9 1.8 2.0 3.4 0.3 6.8 12.0 9.5 3.0 4.7 0.8 1.0 1.0 1.8 5.1 1.9 2.4 2.8 0.2 3.0 2.1 5.6 7.2 0.6 1.8 2.4 3.5 1.2 5.7 1.1 9.0 10.0 2.7 1.7 1.9 1.6 1.8 4.5 1.4 1.5 1.8 1.8 1.3 3.7 2.8 7.0 0.8 3.9 1.0 2.1 4.9 1.5 10.3 5.5 16.6 3.7 5.3 5.1 6.0 9.4 12.3 5.5 4.6 2.8 0.9 5.2 2.4 10.3 2.1 3.1 5.5 2.7 1.9 1.6 4.1 4.4 3.3 2.4 0.4 4.6 2.7 7.8 8.6 7.4 11.2 8.2 8.5 8.6 8.4 8.6 7.8 8.9 7.8 118.6 0.0 6.3 13.1 2.3 1.8 2.5 1.6 4.0 8.1 3.7 4.2 17.7 7.2 1.9 3.7 2.1 0.9 2.0 0.6 7.9 3.1 1.4 1.5 1.5 120.4 0.0 8.4 7.2 0.7 0.7 6.8 0.0 1.5 1.3 8.2 371.2 11.8 3.2 6.7 5.0 0.6 0.0 19.9 1.1 3.3 11.5 3.0 0.0 8.4 2.4 6.8 2.1 7.5 6.0 4.5 0.1 5.3 2.0 1.4 0.9 11.4 2.4 3.5 6.6 11.1 13.0 2.3 3.4 1.5 1.1 0.1 4.0 4.3 0.4 2.1 FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adipose tissue: 3787.4;breast: 2195.7" "Cell type enriched" "Detected in many" 17 "Adipocytes: 24359.7" "Group enriched" "Detected in all" 7 "breast cancer: 42.1;cervical cancer: 141.7;head and neck cancer: 133.8;urothelial cancer: 65.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 171 "ASC diff: 4051.5;RT4: 2107.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002188, CAB024961" Enhanced NA NA 22000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB024961: , HPA002188: AB_1078822" "unprognostic (4.81e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-3)" "unprognostic (2.63e-2)" "unprognostic (2.58e-1)" "unprognostic (8.70e-3)" "unprognostic (1.78e-3)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" "unprognostic (8.76e-2)" "unprognostic (1.13e-3)" "unprognostic (4.48e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-1)" 3787.4 42.2 0.8 46.7 1.1 2.8 2195.7 0.9 1.6 9.9 34.8 52.9 2.8 4.6 0.6 15.1 10.9 68.1 121.8 1.2 0.8 7.0 5.1 113.5 13.6 0.8 0.8 4.2 16.6 59.1 1.4 186.9 0.8 4.3 33.5 2.6 58.8 5.0 66.7 65.2 44.7 14.2 0.7 6.7 26.5 1.1 3.8 29.8 83.0 166.7 2.0 242.7 18.9 0.9 0.0 0.0 0.0 0.0 4051.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 17.9 0.0 0.1 1.3 0.0 0.4 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.8 1.2 0.1 3.0 0.0 9.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 2107.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.2 5.7 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 1.6 1.2 0.8 0.8 0.8 0.8 0.7 3.8 0.9 24359.7 35.3 64.3 0.0 19.4 14.4 1.1 0.9 4.6 0.5 71.7 196.2 42.1 0.0 26.7 0.0 0.0 0.5 73.6 0.0 0.0 0.2 1.6 0.4 8.8 1132.7 0.0 0.0 0.0 5.6 0.7 53.1 1.1 0.2 27.8 0.1 23.2 0.4 114.2 0.0 0.0 0.0 0.0 50.4 15.7 10.9 1.5 192.7 16.0 0.0 0.6 0.9 0.0 0.0 0.0 0.2 2.2 1.2 2.7 0.5 0.0 0.3 21.9 2.4 716.6 62.2 1364.8 0.0 0.1 1.2 13.9 0.7 18.7 2.3 0.0 55.3 FAM124B FLJ22746 ENSG00000124019 "Family with sequence similarity 124 member B" Q9H5Z6 2 224378698-224402107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 8.5" "Group enriched" "Detected in some" 4 "Adipocytes: 13.8;Endothelial cells: 10.8;Erythroid cells: 9.4;granulocytes: 4.5" "Cancer enriched" "Detected in many" 10 "testis cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 29.5;eosinophil: 17.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "HUVEC TERT2: 103.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA070240 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA070240: AB_2686238" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "unprognostic (6.87e-3)" "unprognostic (2.49e-1)" "unprognostic (7.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.28e-2)" "unprognostic (5.78e-2)" "unprognostic (3.19e-1)" "unprognostic (1.85e-1)" "unprognostic (1.57e-1)" "unprognostic (3.36e-1)" "unprognostic (7.61e-3)" "unprognostic (1.36e-2)" "unprognostic (4.30e-1)" "unprognostic (2.25e-1)" "unprognostic (5.80e-3)" 5.2 0.5 1.4 1.1 1.2 4.7 4.3 1.4 1.7 1.5 0.9 0.9 1.0 1.6 0.3 1.4 1.2 1.2 1.8 1.3 1.6 0.6 1.9 2.3 0.7 1.8 1.7 0.4 0.4 2.4 0.2 8.5 1.5 0.5 1.0 0.2 0.8 0.5 1.2 1.8 1.0 2.3 1.6 0.5 0.6 0.3 1.7 1.1 1.0 4.6 0.7 1.5 1.4 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 15.0 0.0 0.1 0.0 0.0 0.0 103.4 0.0 4.8 0.2 0.0 0.1 0.0 0.1 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.7 7.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.5 3.0 17.2 0.2 2.3 0.0 0.0 0.7 0.0 7.9 0.0 0.0 0.0 0.1 5.4 0.8 0.0 2.5 1.1 1.4 1.2 1.4 1.7 1.3 1.6 1.8 1.7 1.5 1.6 1.7 1.1 13.8 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 1.2 0.3 0.2 10.8 0.0 9.4 0.2 0.0 0.1 0.4 0.0 0.8 4.5 0.0 2.2 0.4 0.4 0.0 0.2 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 1.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.1 1.1 0.1 0.0 0.0 FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 50.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 82.4;Early spermatids: 69.0;Hepatocytes: 66.8;Hofbauer cells: 94.0;Late spermatids: 189.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;BJ hTERT+: 27.3;HSkMC: 21.8;U-2197: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" NA NA 13000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "HPA048964: AB_2680575" "unprognostic (3.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-3)" "unprognostic (2.39e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (9.16e-10)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (2.39e-2)" 7.5 1.6 0.4 2.7 0.3 0.6 5.4 0.3 0.6 17.5 2.6 1.6 0.6 12.5 0.1 3.1 6.0 1.3 3.1 0.1 1.1 12.9 50.2 12.6 1.6 0.8 1.7 8.1 1.0 0.3 6.3 2.2 0.7 2.5 0.4 0.1 11.6 0.6 1.6 2.5 2.0 2.3 0.1 4.5 7.8 6.5 3.6 0.4 6.8 0.1 0.5 2.2 5.7 0.7 0.0 0.2 0.0 0.2 1.1 10.1 0.0 0.5 27.3 0.0 0.0 0.0 0.1 0.0 2.0 2.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.0 21.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.1 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.3 0.3 0.6 0.1 1.1 0.8 1.7 0.7 0.1 3.6 0.7 1.4 16.0 82.4 0.7 1.1 2.3 0.1 5.2 0.0 3.2 5.3 0.9 5.2 7.2 21.3 44.1 0.0 0.6 0.4 0.0 0.0 1.2 69.0 6.1 44.4 3.6 0.0 2.7 3.8 0.5 2.2 18.1 42.3 9.7 1.3 2.9 7.5 66.8 94.0 42.1 8.2 0.0 2.0 27.4 3.5 189.3 11.1 26.8 1.8 16.9 1.3 0.2 0.0 4.0 2.1 0.8 0.0 14.7 0.2 0.0 0.0 15.3 0.8 2.8 6.6 3.4 3.0 1.2 0.6 1.2 1.8 2.7 1.0 13.6 0.0 0.1 FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 272.0;Alveolar cells type 1: 60.9;Alveolar cells type 2: 69.9;Breast glandular cells: 87.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 41.3;HUVEC TERT2: 28.0" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" 16.7 4.1 7.7 5.3 8.6 7.2 11.2 16.6 15.5 2.8 0.5 2.8 2.9 3.8 3.8 4.3 2.3 5.1 7.2 6.7 1.7 4.5 4.6 5.1 5.2 1.6 2.3 2.8 2.2 3.9 1.5 10.8 2.9 3.8 2.8 10.5 8.8 2.9 6.0 6.3 3.4 5.1 0.4 5.0 7.3 6.0 3.9 3.2 4.2 5.0 4.1 5.1 2.5 13.7 6.3 2.4 2.5 2.1 12.5 7.1 3.7 5.3 1.2 1.0 1.6 1.9 7.9 41.3 4.9 2.9 3.5 3.1 3.9 5.5 1.8 19.7 6.6 4.4 6.4 3.4 7.4 10.3 2.7 7.8 8.7 1.5 9.1 2.0 28.0 5.8 8.4 19.6 3.1 6.5 3.8 7.4 3.2 10.3 5.9 8.6 4.2 8.5 4.2 6.1 4.6 3.8 5.0 9.0 2.7 3.6 6.5 4.4 17.9 3.2 9.7 2.1 1.9 8.2 11.3 19.1 7.3 5.1 4.1 2.8 0.6 0.6 0.5 0.5 0.4 0.6 0.5 0.4 0.3 0.9 0.5 0.6 1.5 0.6 0.6 1.0 0.6 0.3 7.7 8.6 16.6 15.5 6.7 1.7 1.6 2.3 2.9 0.4 3.9 13.7 272.0 60.9 69.9 0.0 4.9 0.0 0.0 0.0 0.0 0.0 87.0 42.2 0.0 0.0 36.5 33.1 0.0 1.6 9.2 0.0 7.9 12.0 0.0 4.6 3.9 44.0 0.0 0.0 0.0 17.3 2.8 13.8 0.0 12.0 32.8 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 28.2 0.0 0.0 4.0 0.0 0.0 3.5 42.3 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 2.5 9.8 1.3 0.0 0.0 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 83.4;lymphoid tissue: 110.9" "Cell type enhanced" "Detected in many" "Adipocytes: 46.8;Hofbauer cells: 48.7;Kupffer cells: 92.3;Macrophages: 51.9;monocytes: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 315.8" "Group enriched" "Detected in many" 4 "dendritic cells: 162.6;granulocytes: 315.8;monocytes: 151.7" "Cell line enhanced" "Detected in many" "HEL: 63.5;HL-60: 56.9;HMC-1: 116.6;NB-4: 76.1;THP-1: 110.8;U-937: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 30.8 8.0 9.4 20.2 8.8 83.4 21.3 9.6 10.8 18.1 9.6 12.5 5.8 15.7 2.4 5.9 19.0 14.0 19.6 8.3 8.7 18.9 25.2 30.9 13.8 11.1 9.2 13.5 7.8 2.3 5.6 16.3 10.1 17.9 4.6 1.5 58.3 8.0 6.1 8.0 12.5 10.7 10.4 110.9 9.6 4.5 10.9 4.2 16.0 7.0 5.7 15.1 13.5 9.8 0.4 0.8 0.8 10.3 3.1 8.8 17.9 2.9 0.1 5.1 2.9 2.6 0.1 6.8 0.5 6.0 0.2 1.5 1.7 0.3 1.6 3.3 1.1 63.5 0.0 11.9 6.8 56.9 116.6 8.8 0.1 7.6 0.0 0.0 31.2 9.4 1.8 0.2 0.0 21.3 1.8 76.1 3.2 2.5 0.0 8.6 0.1 0.1 0.0 0.2 0.4 0.1 0.0 2.8 2.3 2.9 0.1 110.8 24.9 0.2 10.4 0.2 0.2 0.1 8.0 2.5 0.3 48.0 2.4 64.4 151.7 315.8 0.5 88.6 0.4 5.2 0.3 0.4 162.6 4.1 0.2 0.3 100.5 51.4 39.8 65.0 0.2 81.5 9.4 8.8 9.6 10.8 8.3 8.7 11.1 9.2 10.1 10.4 10.9 9.8 46.8 3.2 5.8 3.6 5.0 3.8 5.4 0.5 0.6 0.2 4.1 3.8 3.4 8.6 0.5 1.8 0.0 5.3 25.6 0.6 3.9 7.3 1.7 2.0 4.2 29.1 3.0 8.0 2.8 4.3 4.2 9.0 2.0 4.2 29.2 10.7 20.0 15.0 48.7 0.0 0.2 2.0 2.0 92.3 27.9 8.4 9.0 51.9 7.2 5.6 57.8 2.5 26.8 2.0 0.3 2.1 2.0 10.1 4.0 3.1 0.7 1.5 0.2 1.9 13.1 4.6 12.9 4.4 15.9 1.0 2.8 4.5 6.7 3.3 3.7 5.2 FGF11 "FHF3, FLJ16061, MGC102953, MGC45269" ENSG00000161958 "Fibroblast growth factor 11" Q92914 17 7438273-7444937 "Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 31.2" "Cell type enhanced" "Detected in many" "Astrocytes: 10.4;Basal respiratory cells: 10.2;Horizontal cells: 18.5;Muller glia cells: 15.2;Suprabasal keratinocytes: 9.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 10.4;HaCaT: 18.4;LHCN-M2: 12.1" "Low region specificity" "Detected in all" "HPA066605, HPA075188" Enhanced Approved Centrosome NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" Centrosome "HPA066605: AB_2685693, HPA075188: AB_2732283" "unprognostic (7.35e-2)" "unprognostic (1.14e-2)" "unprognostic (7.67e-3)" "unprognostic (2.79e-4)" "unprognostic (9.15e-2)" "unprognostic (3.28e-2)" "unprognostic (7.31e-2)" "unprognostic (3.11e-2)" "unprognostic (1.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.69e-2)" "unprognostic (2.89e-3)" "unprognostic (2.00e-6)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (6.90e-3)" "unprognostic (4.97e-3)" 4.0 31.2 7.8 1.5 9.3 0.9 3.4 12.4 6.7 10.9 4.0 1.2 0.6 2.1 0.6 19.9 1.6 1.5 16.5 7.5 6.7 8.1 0.8 1.1 3.5 10.0 9.3 1.7 0.8 0.7 1.5 0.7 9.1 1.6 0.4 14.8 5.8 0.5 7.5 18.5 1.6 1.2 6.5 2.4 1.0 2.4 12.1 2.0 7.0 8.6 5.2 1.4 15.4 6.7 10.4 0.6 5.5 0.1 3.2 0.1 2.7 0.3 3.4 0.4 0.7 0.2 1.1 3.1 0.7 0.2 0.1 18.4 2.1 5.8 1.3 6.4 4.5 5.6 0.7 1.4 0.5 0.2 6.0 0.6 1.6 0.4 0.2 0.6 0.2 2.3 2.2 0.2 12.1 2.4 1.9 2.5 2.0 0.4 0.2 4.9 5.1 1.3 0.7 0.8 1.2 5.7 0.7 0.7 0.5 3.1 0.3 0.4 0.2 0.3 5.7 0.0 0.3 0.4 1.5 0.9 1.4 3.5 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 9.3 12.4 6.7 7.5 6.7 10.0 9.3 9.1 6.5 12.1 6.7 1.8 0.0 0.0 10.4 0.3 5.5 0.4 10.2 7.4 4.7 1.5 1.5 0.4 1.5 4.5 1.8 6.2 0.4 0.5 1.0 3.9 0.6 3.3 1.5 0.9 2.4 0.0 0.0 0.1 0.2 0.4 0.9 0.0 3.9 0.0 2.0 1.4 0.2 0.4 18.5 0.8 0.5 0.0 0.6 2.6 4.6 1.8 0.9 1.8 2.8 0.0 15.2 0.0 5.5 0.3 1.1 0.2 2.2 0.2 0.5 0.8 0.2 7.0 2.8 0.0 2.3 1.6 3.4 2.7 6.3 9.7 0.7 0.5 0.1 0.6 1.2 FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 20 "Early spermatids: 1160.3;Late spermatids: 1540.1" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "ASC diff: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" 35.7 10.3 5.4 4.4 8.5 0.0 16.0 5.8 7.5 27.8 6.2 5.8 2.5 15.0 17.6 9.6 21.5 12.9 5.6 4.9 5.3 6.4 0.4 14.0 1.8 6.3 5.8 11.4 4.6 3.3 1.2 0.6 7.1 4.9 5.0 0.4 2.1 11.1 8.9 5.5 5.1 9.6 5.4 3.5 4.0 65.5 7.2 1.2 8.9 14.6 0.8 6.8 10.3 5.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 8.5 5.8 7.5 4.9 5.3 6.3 5.8 7.1 5.4 7.2 5.5 5.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 0.0 0.1 3.8 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1540.1 52.5 1.1 5.4 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.2 0.0 0.0 0.0 0.0 52.6 1.9 67.4 13.2 4.4 0.0 0.3 0.0 0.6 0.1 0.0 0.2 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 977.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.2;granulocytes: 974.2;monocytes: 1013.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 1749.2;TIME: 1929.6" "CAB004639, HPA051798" Uncertain NA NA 12000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 272.7 185.0 138.4 178.8 177.5 167.0 188.2 88.5 163.2 123.0 112.6 158.6 108.9 165.4 150.1 169.8 131.7 104.5 171.4 166.7 115.8 186.7 98.1 235.2 162.7 92.4 98.9 135.1 114.6 123.0 79.5 218.7 95.6 125.4 188.5 11.8 111.0 119.8 110.3 127.3 117.0 225.1 97.8 185.7 118.3 56.9 120.5 188.1 190.9 150.6 202.2 206.8 126.2 118.9 718.1 299.5 172.9 240.3 654.1 771.3 202.9 423.9 337.1 382.7 354.2 278.4 295.2 272.5 149.3 555.7 656.3 337.7 255.1 1007.2 419.7 68.8 170.5 284.2 113.9 473.3 406.4 390.5 168.0 484.7 332.0 410.3 412.6 513.3 1749.2 401.0 271.0 145.8 443.3 125.8 401.9 453.7 307.1 335.3 276.4 307.0 254.1 351.9 540.0 243.4 248.7 173.8 208.0 479.3 728.8 231.8 177.2 293.0 1929.6 1363.6 201.8 278.1 329.5 76.4 168.1 292.9 248.1 332.3 307.5 316.3 870.8 974.2 112.9 1005.8 104.3 128.1 135.5 133.2 675.2 136.2 140.1 132.6 805.0 160.6 1013.4 312.7 195.0 1153.8 138.4 177.5 88.5 163.2 166.7 115.8 92.4 98.9 95.6 97.8 120.5 118.9 779.1 86.6 77.2 0.0 160.6 263.1 211.2 393.3 152.0 17.6 175.6 156.5 59.7 170.1 179.5 172.9 0.0 281.8 148.3 456.2 238.7 432.4 47.7 98.7 183.8 814.8 330.6 196.4 0.0 337.5 702.0 212.2 160.0 122.5 143.5 95.3 623.6 113.5 746.7 35.3 0.0 245.9 329.6 541.8 436.5 52.2 200.0 428.8 241.9 0.0 527.4 52.2 152.4 0.0 0.0 483.6 977.5 162.9 214.8 221.1 210.8 332.1 123.0 11.7 138.1 87.4 224.7 169.3 141.8 329.4 299.3 231.5 150.1 347.3 318.0 245.7 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FMO3 FMOII ENSG00000007933 "Flavin containing dimethylaniline monoxygenase 3" P31513 1 171090901-171117819 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1123.3" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 412.3" "Cancer enriched" "Detected in many" 13 "liver cancer: 94.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 34.6;ASC TERT1: 26.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA013750 Enhanced NA NA "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA013750: AB_1848968" "unprognostic (1.87e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.64e-1)" "unprognostic (1.31e-3)" "prognostic favorable (3.46e-4)" "prognostic favorable (5.60e-5)" "unprognostic (2.95e-1)" "unprognostic (9.34e-2)" "unprognostic (3.02e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" 27.2 12.4 2.5 0.9 2.7 0.4 6.8 2.5 3.6 1.2 2.3 1.4 1.8 1.3 3.0 5.1 13.3 1.8 4.2 2.3 2.6 14.0 1123.3 18.7 4.9 5.0 2.7 0.3 4.5 4.2 4.3 0.2 3.1 1.1 0.7 0.1 5.1 0.4 4.6 4.3 2.2 1.6 4.0 0.4 3.9 0.5 2.8 1.4 2.6 3.1 9.1 1.0 0.9 2.6 0.0 0.0 0.0 0.0 34.6 26.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.0 7.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.7 2.5 3.6 2.3 2.6 5.0 2.7 3.1 4.0 2.8 2.6 2.7 12.8 0.5 0.0 0.7 0.4 0.4 2.7 0.0 0.0 0.1 0.3 0.4 7.2 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 4.7 0.0 29.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 6.8 412.3 0.0 0.0 0.0 0.0 4.1 9.5 0.8 0.0 0.3 0.1 1.8 1.0 0.0 0.5 0.0 7.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 22.7 0.2 6.6 1.3 6.3 0.4 0.1 0.4 0.4 0.0 0.8 0.2 0.0 0.1 FOXC1 "ARA, FKHL7, FREAC3, IGDA, IHG1, IRID1" ENSG00000054598 "Forkhead box C1" Q12948 6 1609915-1613897 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Deafness, Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "salivary gland: 154.4" "Cell type enhanced" "Detected in many" "Adipocytes: 93.7;Breast myoepithelial cells: 59.4;Endothelial cells: 64.7;Hepatic stellate cells: 65.7;Urothelial cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 92.4;HEK 293: 91.8;RPTEC TERT1: 35.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 18.0" HPA040670 Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA040670: AB_10673412" "unprognostic (2.65e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.53e-4)" "unprognostic (3.22e-2)" "unprognostic (3.22e-2)" "unprognostic (1.24e-1)" "unprognostic (3.30e-2)" "unprognostic (1.54e-2)" "unprognostic (4.04e-3)" "unprognostic (1.58e-1)" "unprognostic (2.33e-3)" "unprognostic (9.55e-2)" "unprognostic (1.11e-2)" "unprognostic (6.48e-2)" "unprognostic (2.04e-1)" "unprognostic (3.83e-3)" "unprognostic (3.74e-1)" 12.3 6.0 7.7 1.2 8.3 0.6 9.0 7.1 9.3 6.3 11.0 1.7 0.9 3.7 1.7 4.8 5.0 7.5 14.0 6.0 6.5 19.9 1.2 3.3 1.7 9.0 7.4 4.7 3.6 1.6 9.5 4.1 8.7 8.6 0.9 0.3 154.4 6.4 2.4 11.1 1.6 2.3 7.1 0.4 1.7 2.0 9.2 8.3 5.6 2.9 2.2 9.4 5.6 7.1 18.0 2.0 0.6 92.4 4.2 4.6 2.9 8.9 10.3 5.4 4.3 6.7 3.7 0.0 10.0 5.2 3.9 19.9 8.8 6.5 4.5 5.7 91.8 3.7 5.3 3.3 2.8 1.4 6.0 15.6 8.7 7.3 8.3 2.8 7.9 0.6 2.7 0.1 2.3 3.8 0.0 2.0 0.3 8.9 7.6 0.0 3.7 0.5 35.9 13.3 3.4 8.0 10.9 0.1 6.4 4.5 2.6 1.5 2.0 11.5 7.1 5.9 9.6 0.4 0.8 0.0 3.2 4.5 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.7 8.3 7.1 9.3 6.0 6.5 9.0 7.4 8.7 7.1 9.2 7.1 93.7 0.0 0.6 0.0 0.4 17.7 31.9 26.3 13.6 0.0 42.2 59.4 7.1 0.0 23.6 11.0 0.0 5.3 1.9 0.9 1.9 3.9 0.6 8.6 1.1 64.7 0.0 0.0 0.0 17.1 0.6 21.2 1.5 3.8 0.0 0.7 65.7 0.4 1.3 0.0 0.0 1.5 8.2 1.3 5.5 1.4 16.1 2.7 1.8 23.4 0.0 0.3 0.0 0.5 0.1 16.2 0.1 28.2 0.1 9.5 0.0 7.4 34.9 0.0 0.0 19.2 40.4 0.7 3.1 11.2 6.5 0.8 1.1 4.4 0.6 64.9 FXYD5 OIT2 ENSG00000089327 "FXYD domain containing ion transport regulator 5" Q96DB9 19 35154730-35169881 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 462.9;Hofbauer cells: 430.3;Langerhans cells: 492.1;Pancreatic endocrine cells: 585.0;T-cells: 459.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010817 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "HPA010817: AB_1849214" "unprognostic (3.97e-3)" "unprognostic (5.49e-2)" "unprognostic (6.37e-3)" "unprognostic (3.01e-1)" "unprognostic (2.50e-3)" "unprognostic (4.39e-3)" "unprognostic (4.68e-2)" "unprognostic (1.56e-3)" "unprognostic (3.85e-1)" "unprognostic (5.66e-3)" "unprognostic (4.78e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.71e-9)" "unprognostic (6.07e-2)" "unprognostic (7.88e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" 203.1 39.2 30.8 130.8 31.0 275.2 171.1 31.9 47.2 226.2 36.9 59.0 28.6 75.5 20.1 116.1 103.6 68.8 82.3 29.9 36.6 42.0 40.2 148.5 187.4 43.4 34.7 28.6 28.0 17.2 39.8 91.7 37.9 68.8 43.3 3.5 70.3 46.5 28.6 85.8 106.6 59.8 35.4 238.3 67.9 9.2 40.0 85.0 59.2 32.6 187.8 104.8 183.8 39.9 932.2 216.7 0.2 0.9 310.5 390.2 213.6 521.7 686.4 362.8 269.3 61.9 263.6 212.9 139.3 632.2 130.3 212.3 132.5 321.3 231.4 265.7 87.9 397.7 111.8 0.5 244.3 228.6 378.0 233.6 141.6 265.3 452.2 213.2 348.5 58.0 380.0 989.0 229.5 1.5 27.4 95.1 66.4 853.4 126.0 127.6 45.0 272.7 134.0 5.2 38.8 0.3 287.1 148.6 316.6 115.0 78.0 180.4 494.8 443.6 170.0 487.7 40.2 1.5 16.2 54.4 675.9 524.8 694.4 644.0 596.4 111.1 451.5 628.4 422.0 602.8 756.5 467.4 718.7 545.6 489.2 405.6 140.1 840.8 636.9 325.0 894.6 934.1 30.8 31.0 31.9 47.2 29.9 36.6 43.4 34.7 37.9 35.4 40.0 39.9 291.0 3.2 13.4 0.0 330.7 107.1 73.4 106.3 54.1 0.6 80.2 51.2 5.2 32.9 27.8 99.3 0.0 18.9 349.7 2.9 0.0 156.1 1.7 3.4 63.5 276.5 10.7 111.2 2.2 197.3 462.9 93.1 71.9 2.2 361.5 0.3 323.8 6.1 430.3 0.0 0.4 8.2 4.1 385.9 492.1 4.6 6.5 403.9 209.9 10.3 243.7 0.4 260.6 1.0 0.1 585.0 7.8 0.7 302.5 72.2 0.2 4.4 5.5 0.4 65.7 5.7 107.6 1.6 8.1 24.0 69.2 50.9 459.5 0.7 10.0 100.3 GARRE1 KIAA0355 ENSG00000166398 "Granule associated Rac and RHOG effector 1" O15063 19 34254552-34355566 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 126.8;Cardiomyocytes: 15.7;Cytotrophoblasts: 23.8;Extravillous trophoblasts: 25.1;Syncytiotrophoblasts: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014570 Uncertain Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA014570: AB_1852307" "unprognostic (1.88e-2)" "unprognostic (8.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.75e-2)" "unprognostic (2.17e-2)" "unprognostic (1.48e-3)" "unprognostic (9.05e-2)" "unprognostic (8.27e-2)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.34e-1)" "unprognostic (7.73e-3)" "unprognostic (2.96e-2)" "unprognostic (1.86e-1)" "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" 18.8 5.6 5.0 7.2 6.7 3.4 16.8 7.3 4.5 10.8 6.7 7.8 5.4 11.0 3.0 8.0 10.1 9.5 12.0 3.6 5.6 8.2 7.3 12.4 9.1 7.0 7.0 9.4 10.4 10.8 7.7 23.3 6.6 8.3 5.6 8.1 7.4 6.4 15.4 10.3 8.2 8.6 5.2 16.1 6.6 7.1 7.1 8.5 10.9 17.0 7.5 8.0 9.9 10.3 3.4 10.2 8.9 4.6 6.0 5.7 11.6 7.6 6.2 5.7 8.4 8.1 3.9 7.7 16.4 7.1 7.1 2.4 6.6 3.6 6.2 11.0 5.8 4.7 3.9 6.2 7.6 2.1 3.7 6.7 6.2 7.5 11.0 22.6 23.7 4.3 14.4 3.8 6.2 1.8 1.4 1.9 6.8 4.6 3.7 3.4 6.2 4.1 4.8 3.8 10.3 8.5 8.7 33.9 10.9 12.9 2.7 3.8 19.7 19.5 7.2 5.0 8.1 6.4 9.5 2.4 3.7 0.8 9.7 0.0 0.7 0.0 0.8 1.4 1.3 2.3 1.8 0.8 0.8 2.8 1.6 1.0 2.2 1.5 2.1 1.1 3.0 0.8 5.0 6.7 7.3 4.5 3.6 5.6 7.0 7.0 6.6 5.2 7.1 10.3 126.8 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.0 23.8 10.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 25.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 34.1 2.3 0.0 0.0 0.0 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Cell type enhanced" "Detected in some" "Adipocytes: 26.7;Endothelial cells: 26.4;Hepatic stellate cells: 24.7;Sertoli cells: 6.6;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 18.7;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 40.6 6.9 7.0 3.3 6.2 0.5 22.1 6.0 8.8 4.9 6.2 4.2 0.9 7.4 0.7 2.6 6.0 3.3 23.8 5.6 5.9 24.6 3.6 28.6 0.9 8.0 7.5 3.5 3.7 1.4 5.9 4.0 8.6 5.8 0.7 0.9 2.9 0.9 5.7 2.9 5.1 2.5 6.5 4.1 5.6 1.7 10.7 0.5 18.2 2.5 0.6 7.0 4.9 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.7 1.1 0.0 0.1 0.0 2.0 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.8 0.0 0.0 0.3 0.3 0.0 18.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 31.3 0.1 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 6.2 6.0 8.8 5.6 5.9 8.0 7.5 8.6 6.5 10.7 6.3 26.7 0.0 0.5 0.7 0.1 2.4 0.2 0.0 1.2 0.1 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.3 26.4 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.2 0.0 0.0 24.7 0.1 0.3 0.0 0.2 0.0 0.0 1.2 1.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 6.6 0.6 16.8 0.0 0.2 0.1 1.3 0.0 0.1 0.3 0.0 0.3 GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 490.3" "Cell type enhanced" "Detected in many" "Early spermatids: 197.7;Late spermatids: 269.9;Oligodendrocytes: 171.0" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Cell line enhanced" "Detected in many" "EFO-21: 92.5;HHSteC: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" 25.3 7.0 249.1 4.4 428.3 0.1 19.6 365.2 263.4 12.8 13.1 8.1 5.7 13.1 14.8 8.1 20.1 15.3 40.7 245.8 278.4 22.4 3.2 5.8 7.8 379.4 327.1 22.6 21.7 45.9 14.1 15.7 333.0 9.6 2.4 17.4 40.1 17.7 72.7 7.5 11.1 7.5 262.7 2.5 41.3 34.0 315.0 3.2 13.8 73.8 3.4 12.8 8.6 490.3 1.2 29.9 29.0 5.2 29.3 2.0 5.3 0.3 7.4 2.9 1.8 28.0 1.0 0.0 92.5 1.0 18.9 1.6 21.6 0.2 1.7 0.2 8.6 0.0 0.1 0.0 60.3 0.0 0.0 2.5 0.0 4.9 0.0 7.9 14.3 0.7 6.6 0.6 6.7 1.5 0.1 0.1 31.8 0.0 15.6 8.9 0.0 0.2 1.1 13.8 22.9 1.9 3.6 1.9 27.2 9.1 0.1 0.6 2.9 0.0 3.5 14.4 0.8 0.4 0.1 0.3 1.4 0.3 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 249.1 428.3 365.2 263.4 245.8 278.4 379.4 327.1 333.0 262.7 315.0 490.3 71.4 0.0 3.0 75.4 1.2 1.3 5.3 2.6 9.1 30.7 22.5 16.3 15.7 40.0 7.2 31.3 0.0 5.0 0.3 0.2 1.9 65.3 197.7 4.1 20.7 44.8 0.0 0.0 2.4 64.5 1.4 14.8 31.6 13.7 0.0 0.4 9.3 0.2 4.1 0.0 13.5 0.0 38.7 1.6 2.6 269.9 23.9 2.2 16.0 7.5 1.0 24.8 0.0 51.8 171.0 72.8 0.0 26.7 1.3 12.3 0.0 0.3 3.3 6.0 13.1 3.3 13.0 4.9 1.6 2.4 1.7 2.5 0.8 7.0 0.2 1.6 HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777998 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "brain: 397.5" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 463.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 27.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.5" "Cell line enhanced" "Detected in many" "HDLM-2: 120.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA007611: AB_1850730" "unprognostic (1.35e-3)" "unprognostic (1.49e-2)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (5.50e-2)" "unprognostic (9.44e-2)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.42e-3)" "unprognostic (4.58e-2)" "prognostic favorable (9.99e-4)" "unprognostic (1.38e-1)" "unprognostic (7.82e-2)" "unprognostic (3.93e-3)" "unprognostic (1.03e-2)" 19.8 9.2 253.4 6.9 359.7 15.0 10.3 124.8 187.0 4.3 39.4 6.6 7.4 6.0 4.1 9.2 8.8 4.7 30.3 146.3 235.5 25.5 14.9 10.7 4.1 253.8 268.7 5.5 11.5 11.5 8.9 10.1 192.5 9.3 4.8 27.8 12.1 5.7 23.5 3.0 6.3 3.9 187.4 6.9 14.5 1.9 318.3 6.9 9.3 17.0 4.2 6.0 5.2 397.5 11.7 51.4 23.2 14.3 55.2 39.4 2.7 6.4 6.3 7.0 7.3 3.8 6.3 0.0 14.3 12.1 43.2 0.6 10.7 16.6 17.5 120.9 4.3 53.7 8.7 18.4 31.0 14.9 14.0 60.3 10.5 32.4 47.9 16.5 17.6 10.0 31.7 14.4 54.3 8.9 18.9 10.6 5.9 6.6 34.3 22.1 12.7 1.6 31.5 2.0 14.1 12.9 14.4 0.5 7.0 4.3 7.9 6.0 59.5 24.5 11.6 28.5 31.4 68.7 44.3 10.2 49.4 7.7 13.4 27.5 1.3 3.5 0.2 1.1 0.3 0.6 0.5 0.2 0.6 0.5 1.6 0.5 1.7 0.2 4.1 0.2 0.1 0.7 253.4 359.7 124.8 187.0 146.3 235.5 253.8 268.7 192.5 187.4 318.3 397.5 107.8 16.0 31.2 82.6 45.8 9.3 30.6 24.9 16.5 116.0 65.6 32.6 213.9 55.8 35.6 64.4 152.2 8.8 72.0 38.4 35.2 32.5 3.1 39.1 12.2 80.3 67.2 18.5 17.8 67.0 1.5 28.1 70.8 41.7 44.9 24.3 151.0 145.2 15.7 222.1 36.3 32.2 63.1 119.5 10.9 4.0 13.1 53.2 44.4 49.6 47.6 78.0 95.8 145.3 463.7 63.4 24.6 18.8 97.9 118.9 22.5 75.0 48.7 62.9 46.0 96.6 60.8 2.7 4.8 42.5 9.5 9.6 30.5 20.1 29.3 43.9 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HYAL2 "LuCa-2, LUCA2" ENSG00000068001 "Hyaluronidase 2" Q12891 3 50317790-50322782 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 282.8" "Group enriched" "Detected in many" 5 "Adipocytes: 497.6;Endothelial cells: 216.3;Hepatic stellate cells: 253.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "HUVEC TERT2: 363.3;TIME: 502.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036436 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA036436: AB_10670104" "unprognostic (9.97e-3)" "unprognostic (2.60e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-3)" "unprognostic (3.44e-1)" "unprognostic (7.41e-2)" "unprognostic (7.93e-2)" "unprognostic (4.70e-1)" "unprognostic (1.44e-1)" "unprognostic (6.76e-2)" "unprognostic (2.36e-1)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (7.36e-2)" "unprognostic (2.72e-1)" "unprognostic (7.02e-3)" "unprognostic (5.62e-2)" 97.4 62.6 24.7 29.1 23.0 3.1 93.9 24.9 28.3 51.6 24.3 34.0 17.9 66.1 10.3 39.7 55.6 47.5 92.2 22.3 24.8 85.1 32.2 186.8 40.0 26.0 24.9 29.1 27.9 25.7 41.6 87.4 27.5 37.2 11.5 3.3 37.5 22.0 30.9 37.1 38.7 37.4 27.1 282.8 38.6 22.0 28.1 9.5 80.9 35.7 14.6 47.0 45.8 24.9 26.8 38.5 63.0 64.1 38.2 32.9 39.6 29.8 41.2 42.0 32.6 44.6 77.3 7.0 102.4 43.6 82.5 27.4 24.6 58.7 12.0 14.2 19.6 9.7 34.9 69.2 33.0 8.1 24.4 51.9 48.8 42.1 13.8 38.1 363.3 18.2 17.6 8.0 35.4 37.0 17.7 16.6 72.0 23.2 55.7 15.5 12.4 26.1 52.4 24.2 16.6 53.3 30.4 31.2 31.8 21.2 34.4 20.3 502.9 50.0 49.7 33.5 47.5 13.9 24.1 21.6 29.4 25.5 73.0 0.0 9.5 10.7 1.4 14.1 3.0 1.1 1.3 3.8 5.3 1.5 0.4 0.7 9.2 2.8 13.6 4.0 1.9 3.3 24.7 23.0 24.9 28.3 22.3 24.8 26.0 24.9 27.5 27.1 28.1 24.9 497.6 19.2 9.9 5.2 3.6 13.0 28.6 45.2 11.4 7.8 17.6 16.6 7.3 32.9 30.9 33.1 6.2 33.6 4.1 13.5 11.7 53.0 4.7 8.5 19.8 216.3 7.3 10.1 1.6 38.7 38.4 26.6 16.8 13.8 0.0 31.5 253.1 9.1 46.2 8.4 1.9 13.0 42.7 12.6 9.3 5.0 24.5 9.4 17.8 15.9 7.6 19.7 5.2 4.0 3.4 45.6 13.5 22.2 4.2 45.3 16.1 11.8 11.0 6.1 39.5 11.2 26.0 11.2 56.0 24.9 12.6 32.7 4.1 50.0 16.6 33.3 ICAM5 "TLCN, TLN" ENSG00000105376 "Intercellular adhesion molecule 5" Q9UMF0 19 10289952-10296778 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 40.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Cardiomyocytes: 33.9;Erythroid cells: 8.2;Excitatory neurons: 17.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.8" "Group enriched" "Detected in many" 239 "amygdala: 13.6;basal ganglia: 15.4;cerebral cortex: 26.2;hippocampal formation: 40.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 16.3;K-562: 13.2;RPMI-8226: 14.7;U-266/70: 17.5;U-87 MG: 9.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 14 "amygdala: 40.8;basal ganglia: 45.1;cerebral cortex: 50.7;hippocampal formation: 76.2;olfactory bulb: 27.4" "HPA008943, HPA009083, CAB025178" Enhanced NA NA 3300000 "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "CAB025178: , HPA008943: AB_1079095, HPA009083: AB_1079094" "unprognostic (7.76e-2)" "unprognostic (1.91e-1)" "unprognostic (1.66e-2)" "unprognostic (4.24e-2)" "unprognostic (8.23e-3)" "unprognostic (2.58e-1)" "unprognostic (8.12e-2)" "unprognostic (9.99e-3)" "unprognostic (2.58e-1)" "unprognostic (2.44e-2)" "unprognostic (3.90e-3)" "unprognostic (9.89e-3)" "unprognostic (5.29e-5)" "unprognostic (6.47e-2)" "unprognostic (4.86e-2)" "unprognostic (5.44e-3)" "unprognostic (6.28e-3)" 0.3 0.0 13.6 0.0 15.4 0.6 0.2 0.0 26.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 1.2 40.2 0.0 1.0 0.0 6.2 0.2 0.0 0.0 2.1 0.0 0.1 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.6 0.0 0.0 0.2 0.5 0.0 3.5 0.0 0.0 7.4 0.0 0.0 0.3 5.0 0.8 0.2 0.5 0.0 0.1 5.6 2.3 0.0 0.0 6.5 0.2 0.0 0.0 0.2 1.0 16.3 6.1 0.5 0.1 0.0 3.1 0.0 0.6 0.1 0.0 0.0 0.0 2.0 13.2 0.1 0.0 0.8 0.0 2.3 0.0 0.3 4.9 0.1 0.0 14.7 0.2 0.0 0.9 0.1 2.3 0.2 0.5 0.0 2.7 0.0 0.0 1.5 0.0 0.9 0.0 17.5 3.1 3.5 9.9 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 15.4 0.0 26.2 40.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 6.4 2.8 1.6 0.4 0.3 0.2 0.3 1.8 0.7 1.6 5.2 33.9 0.0 1.3 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.5 0.6 0.5 2.8 0.0 8.2 17.7 0.0 0.1 1.1 1.1 1.3 2.5 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.3 1.7 0.0 0.0 2.1 0.0 2.8 0.3 0.0 0.0 1.5 0.9 0.1 0.0 0.0 0.1 0.3 0.1 0.4 0.5 0.0 0.0 0.7 1.7 1.7 1.3 0.4 0.1 0.1 0.7 0.1 0.2 0.2 IFI16 "IFNGIP1, PYHIN2" ENSG00000163565 "Interferon gamma inducible protein 16" Q16666 1 158999968-159055155 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002134, CAB016293, HPA073514" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nucleoli" Cytosol "CAB016293: AB_627775, HPA002134: AB_1079099, HPA073514: " "unprognostic (7.23e-3)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (7.70e-3)" "unprognostic (1.87e-1)" "unprognostic (6.08e-2)" "unprognostic (1.80e-1)" "unprognostic (5.83e-2)" "unprognostic (5.04e-2)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (5.07e-2)" "unprognostic (4.08e-1)" "unprognostic (7.97e-2)" "unprognostic (1.14e-1)" 95.7 37.9 13.5 114.5 17.5 35.5 72.8 14.3 14.1 56.8 9.1 38.3 23.8 76.5 22.7 63.6 54.2 100.6 35.0 13.7 20.3 30.1 27.7 68.2 140.6 29.9 22.7 76.8 16.7 9.7 9.3 66.7 27.0 26.5 45.0 7.7 63.7 32.0 16.8 58.8 47.9 87.3 23.6 107.8 30.7 18.8 23.8 116.8 37.4 32.6 133.1 113.6 52.8 26.2 43.5 3.2 14.4 0.6 97.4 319.5 0.4 89.9 238.0 245.7 324.2 0.0 54.1 251.7 75.4 55.3 79.2 122.2 2.2 91.1 97.7 78.4 1.1 64.9 17.2 0.1 181.8 22.8 4.2 302.4 159.5 126.5 177.8 117.8 262.8 218.1 1.4 179.4 138.6 0.0 302.2 21.1 38.4 0.0 32.5 140.6 91.4 295.0 34.4 16.1 6.6 0.1 117.7 1.0 259.5 56.9 0.4 26.3 150.2 63.1 29.7 179.9 38.2 165.8 82.8 235.5 181.2 72.7 155.7 9.1 67.7 0.4 57.5 66.4 51.9 88.4 54.3 59.4 68.3 94.6 33.9 43.3 164.4 91.6 65.3 51.1 82.1 63.8 13.5 17.5 14.3 14.1 13.7 20.3 29.9 22.7 27.0 23.6 23.8 26.2 378.4 38.5 54.6 4.2 217.8 95.0 110.7 197.6 174.8 0.4 47.8 43.8 10.7 37.1 130.7 42.3 0.0 3.4 278.3 7.9 1.9 38.0 4.9 41.9 219.1 286.8 12.1 38.7 1.3 47.8 2.9 207.8 9.7 68.0 138.3 27.7 137.4 3.0 214.2 0.0 2.2 19.9 79.3 163.8 135.0 9.8 117.4 187.2 83.6 116.2 202.4 30.8 329.6 37.2 20.7 47.1 23.5 53.0 143.3 32.6 7.9 4.9 76.6 1.4 85.5 185.3 132.7 2.4 13.2 92.6 68.2 3.3 219.2 70.6 26.4 107.5 IFITM1 "9-27, CD225, DSPA2a, IFI17" ENSG00000185885 "Interferon induced transmembrane protein 1" P13164 11 310041-315272 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, Osteogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 673.8;Endothelial cells: 364.4;Leydig cells: 300.8;Sertoli cells: 276.1;T-cells: 595.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1494.7;gdT-cell: 2906.3;MAIT T-cell: 2003.4;memory CD4 T-cell: 3120.6;memory CD8 T-cell: 3000.3;naive CD4 T-cell: 2939.3;naive CD8 T-cell: 2996.4;neutrophil: 2741.6;NK-cell: 4679.9;T-reg: 1944.8" "Group enriched" "Detected in all" 7 "granulocytes: 2741.6;NK-cells: 4679.9;T-cells: 3120.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1038.8;BJ hTERT+ SV40 Large T+: 2266.3;BJ hTERT+ SV40 Large T+ RasG12V: 4016.8;HMC-1: 1138.9" "HPA004810, CAB017615" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus" "Plasma membrane, Cytosol" "CAB017615: AB_2264496, HPA004810: AB_1851419" "unprognostic (1.03e-3)" "unprognostic (6.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-1)" "unprognostic (9.06e-2)" "unprognostic (7.58e-2)" "unprognostic (3.03e-1)" "unprognostic (6.21e-2)" "unprognostic (5.53e-2)" "unprognostic (6.64e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (5.77e-9)" "unprognostic (7.29e-2)" "unprognostic (6.29e-2)" "unprognostic (3.15e-2)" "unprognostic (3.82e-2)" 477.7 102.3 291.8 282.0 303.4 367.1 401.7 293.8 402.1 563.3 321.5 249.0 128.4 314.6 1152.4 147.4 537.4 247.9 368.4 292.6 305.4 317.5 191.4 246.5 417.2 324.8 295.6 607.5 78.8 154.0 145.1 278.5 322.5 190.6 172.0 14.9 199.8 324.3 134.2 164.6 252.4 367.4 308.6 679.7 141.6 56.3 317.5 296.5 263.4 259.3 295.9 307.4 364.7 304.3 125.7 5.5 1011.4 74.5 79.1 279.8 7.4 250.1 1038.8 2266.3 4016.8 3.7 782.2 3.0 157.9 257.1 23.5 269.0 36.5 26.2 52.0 255.3 51.8 125.9 77.5 11.8 668.2 182.8 1138.9 496.3 0.2 26.6 2.6 27.0 4.2 41.1 450.0 880.7 1.7 23.9 85.1 318.2 264.5 0.5 33.5 27.1 3.1 24.5 654.9 0.0 1.0 2.2 122.7 11.9 196.9 138.5 42.1 17.0 8.8 3.8 4.7 1.5 1.1 61.6 44.8 6.8 3.4 253.8 3.1 544.4 62.1 1494.7 2906.3 312.7 2003.4 364.9 3120.6 3000.3 114.2 323.6 2939.3 2996.4 2741.6 4679.9 539.0 33.7 1944.8 4673.8 291.8 303.4 293.8 402.1 292.6 305.4 324.8 295.6 322.5 308.6 317.5 304.3 240.7 35.3 119.4 2.6 88.2 27.9 17.1 70.2 673.8 0.0 13.0 12.6 8.4 2.8 115.3 33.1 0.0 3.3 258.6 13.7 5.9 1.7 1.4 14.6 96.5 364.4 1.2 27.8 0.0 1.4 30.7 236.0 33.6 20.8 18.9 5.6 164.6 24.6 11.8 0.0 0.0 17.3 10.2 10.1 26.8 3.8 300.8 45.4 78.2 42.2 2.1 0.0 126.7 0.0 0.2 0.7 15.0 124.5 141.2 2.3 15.0 1.0 26.0 0.0 276.1 16.4 213.4 0.6 1.5 50.4 14.3 4.0 595.8 2.1 29.2 5.7 IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 86.7;cervix: 89.0" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 1279.3;Leydig cells: 1103.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Cell line enhanced" "Detected in some" "ASC diff: 37.9;HDLM-2: 49.6;K-562: 22.4;Karpas-707: 11.3;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048946 Approved "Secreted to blood" NA NA 103000000 330000000 "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" 86.7 5.1 1.2 27.1 1.8 0.9 38.7 0.3 2.3 89.0 1.3 6.9 5.4 46.9 10.6 6.6 13.0 21.5 15.1 2.2 1.0 3.1 83.5 11.6 6.5 2.5 1.1 9.0 3.9 1.4 1.2 24.2 2.0 38.5 6.7 5.4 7.6 33.4 8.5 4.9 5.7 74.3 1.2 9.8 7.7 7.6 2.0 3.1 25.4 5.9 3.7 21.3 22.7 0.9 0.3 0.0 0.0 0.0 37.9 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 22.4 11.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.2 0.2 1.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.4 1.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.8 0.3 2.3 2.2 1.0 2.5 1.1 2.0 1.2 2.0 0.9 11.8 3.2 2.2 1.0 8.5 2.5 0.7 0.0 1.8 168.1 4.0 6.2 0.4 2.8 0.7 0.0 0.0 1.1 0.6 0.2 0.0 0.0 17.5 35.8 1279.3 38.9 0.0 5.3 1.2 0.6 1.5 259.7 2.6 34.5 0.0 0.3 6.4 243.0 122.0 0.0 123.9 0.0 16.2 25.8 12.5 58.0 1103.2 42.0 14.2 27.2 3.6 4.4 0.0 0.5 0.9 0.1 0.0 193.4 66.9 1.2 0.0 1.4 0.1 9.0 0.0 139.3 19.6 1.9 1.2 1.6 2.7 1.2 9.1 69.4 0.2 0.4 IKBIP "FLJ31051, IKIP" ENSG00000166130 "IKBKB interacting protein" Q70UQ0 12 98613405-98645113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.1" "Cell line enhanced" "Detected in all" "BJ: 206.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038677, HPA038678, HPA061541" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA038677: AB_2676146, HPA038678: AB_10672723, HPA061541: AB_2684555" "unprognostic (3.06e-1)" "unprognostic (1.06e-3)" "unprognostic (2.13e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (4.00e-5)" "unprognostic (6.28e-3)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (7.37e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.60e-9)" "unprognostic (7.37e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-1)" "unprognostic (3.16e-2)" 14.0 7.1 2.3 15.3 2.8 5.1 10.1 2.3 3.1 12.6 5.0 6.6 4.1 10.3 5.8 4.8 6.7 12.9 9.3 2.3 2.9 8.3 10.3 11.0 12.6 3.2 2.7 5.9 5.8 4.2 7.7 26.8 3.2 6.8 7.0 1.2 6.1 7.4 2.6 3.1 5.7 16.0 2.9 11.8 5.6 4.6 3.1 11.6 9.3 4.8 9.6 17.1 7.4 3.7 13.0 39.8 43.5 28.4 102.8 105.8 39.4 206.0 124.7 53.3 67.2 8.8 12.4 42.4 35.5 128.7 37.1 26.7 17.5 80.5 90.1 12.4 26.7 16.2 23.9 59.8 39.3 30.2 31.1 81.1 16.6 62.4 54.5 95.3 75.3 7.8 25.5 16.0 133.3 11.8 14.0 68.7 16.9 10.2 33.5 11.9 64.0 21.7 88.9 14.6 6.6 20.8 58.9 4.1 34.1 73.6 13.1 37.0 71.6 115.7 41.3 50.5 53.9 17.2 20.1 31.8 33.3 27.2 85.1 11.4 6.4 19.3 2.8 4.9 3.3 5.9 1.8 2.9 5.4 3.8 2.0 2.0 28.1 5.0 5.7 3.7 2.6 1.8 2.3 2.8 2.3 3.1 2.3 2.9 3.2 2.7 3.2 2.9 3.1 3.7 44.9 12.8 15.7 1.6 34.4 7.6 15.5 55.6 21.6 2.8 7.9 22.4 3.0 0.0 18.7 3.7 4.2 35.5 32.5 2.3 11.7 10.5 2.8 7.9 47.4 47.7 0.0 19.8 5.9 5.8 65.3 47.0 2.6 4.4 20.8 32.7 44.3 8.4 45.7 3.3 3.3 4.8 12.2 31.2 34.1 3.6 30.7 35.4 14.2 14.0 40.4 2.0 37.0 11.6 2.2 5.1 3.1 17.0 74.8 7.6 1.0 10.1 6.3 2.6 39.5 27.8 46.8 32.1 16.0 9.0 7.2 10.1 23.6 25.3 2.9 6.5 IL27RA "CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1" ENSG00000104998 "Interleukin 27 receptor subunit alpha" Q6UWB1 19 14031762-14053218 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.5" "Cell type enhanced" "Detected in many" "B-cells: 49.1;dendritic cells: 56.6;Kupffer cells: 41.1;Langerhans cells: 44.2;NK-cells: 69.0;T-cells: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073441 Approved Vesicles NA NA 4900000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA073441: " "prognostic favorable (1.74e-6)" "unprognostic (1.99e-1)" "unprognostic (1.55e-1)" "unprognostic (6.09e-2)" "unprognostic (2.03e-3)" "unprognostic (2.28e-1)" "unprognostic (2.05e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (1.40e-3)" "unprognostic (9.92e-2)" "unprognostic (3.35e-2)" "prognostic unfavorable (2.58e-10)" "unprognostic (5.45e-3)" "unprognostic (3.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.87e-3)" 7.8 1.7 2.4 8.7 2.3 2.7 6.5 2.2 2.7 2.7 2.2 3.1 2.3 2.4 0.7 2.6 3.3 2.3 7.7 2.8 2.9 6.1 1.5 8.0 12.6 2.5 2.5 1.0 2.8 5.6 0.8 1.3 2.7 3.6 2.1 0.2 3.0 1.2 2.0 2.2 8.1 1.9 2.5 14.7 2.8 2.0 3.1 11.1 4.0 2.4 16.5 3.9 2.8 2.4 7.7 3.3 3.2 4.4 0.2 1.6 1.3 3.5 7.3 6.3 9.0 1.6 6.1 0.1 3.6 3.1 2.9 1.4 5.1 2.1 4.8 14.8 3.5 18.6 0.7 2.7 0.5 9.0 0.2 1.6 0.8 3.0 0.6 5.1 2.5 4.6 13.1 13.5 0.3 10.7 6.8 19.5 4.2 4.5 2.2 5.8 1.9 7.1 3.9 1.8 2.8 1.5 4.5 0.3 5.2 1.7 5.6 5.4 4.0 0.6 7.7 6.4 3.8 13.9 7.2 6.7 0.6 18.2 4.2 7.9 22.5 0.6 24.3 18.4 21.4 15.6 24.0 20.2 20.7 12.8 26.1 20.6 1.6 22.9 9.5 7.6 23.1 21.4 2.4 2.3 2.2 2.7 2.8 2.9 2.5 2.5 2.7 2.5 3.1 2.4 30.4 0.0 10.0 0.0 49.1 1.9 13.3 8.5 3.4 0.3 14.0 11.9 5.4 5.7 5.7 3.7 0.0 0.6 56.6 0.7 0.0 10.7 0.4 1.9 1.2 22.8 2.4 7.2 2.4 2.7 1.4 4.0 3.6 1.5 17.7 1.4 22.9 0.7 21.4 1.7 2.1 0.9 4.1 41.1 44.2 0.5 3.4 32.8 5.4 1.0 22.8 0.3 69.0 1.0 0.6 3.8 0.8 3.4 26.0 12.4 0.0 0.9 2.0 0.0 0.0 1.9 2.2 0.1 11.5 2.6 1.3 0.1 63.5 0.4 2.4 3.5 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 INHBB ENSG00000163083 "Inhibin subunit beta B" P09529 2 120346136-120351803 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 52.5;breast: 43.3" "Group enriched" "Detected in many" 7 "Adipocytes: 200.5;Granulosa cells: 653.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 44.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 47.6;ASC diff: 63.1;BJ hTERT+ SV40 Large T+ RasG12V: 38.5;MCF7: 58.4;PC-3: 91.7;SK-BR-3: 163.4;T-47d: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 130000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.80e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.26e-2)" "unprognostic (4.26e-2)" "unprognostic (3.61e-3)" "unprognostic (2.13e-2)" "unprognostic (5.52e-2)" "unprognostic (6.99e-2)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.57e-3)" "unprognostic (4.14e-1)" "prognostic favorable (1.02e-4)" "unprognostic (1.76e-2)" 52.5 3.7 5.6 0.9 5.5 0.2 43.3 8.0 4.0 6.9 3.4 3.4 1.3 7.4 2.6 2.5 6.2 2.5 6.4 3.9 4.8 4.3 20.2 4.4 1.1 9.7 7.4 2.5 4.2 6.3 8.0 1.2 6.0 8.2 0.3 1.0 16.4 0.8 10.4 17.1 2.4 2.2 6.2 0.5 3.6 17.1 7.9 0.4 20.9 2.4 0.7 8.2 6.4 4.2 24.5 47.6 0.2 0.0 63.1 4.9 0.0 3.3 3.8 20.7 38.5 1.0 0.0 0.0 8.3 1.2 0.1 0.1 3.7 0.0 28.9 0.1 0.8 0.0 0.0 1.2 1.0 0.0 0.1 2.6 3.5 0.7 0.0 0.3 0.4 0.0 0.0 0.0 0.1 58.4 0.0 0.1 0.0 4.7 91.7 0.0 0.0 1.2 5.6 0.0 5.4 0.0 0.2 163.4 0.0 0.0 39.2 0.5 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.6 5.5 8.0 4.0 3.9 4.8 9.7 7.4 6.0 6.2 7.9 4.2 200.5 3.2 2.2 8.1 0.2 4.0 2.2 5.5 0.0 0.1 53.7 24.4 0.7 8.6 9.2 1.8 25.0 0.1 0.7 0.1 0.0 0.4 0.6 9.2 1.6 24.3 0.0 2.7 0.1 0.0 0.2 9.8 0.0 12.5 0.0 653.3 24.7 19.4 0.1 0.0 1.3 0.0 8.2 1.3 6.6 3.6 11.8 1.3 1.8 1.0 0.0 0.2 0.0 2.5 0.0 0.2 0.0 6.8 0.3 8.9 0.0 0.0 30.0 0.6 0.0 37.3 3.1 0.8 6.0 0.6 3.0 0.1 0.6 0.2 0.0 3.2 ITPRIPL1 KIAA1754L ENSG00000198885 "ITPRIP like 1" Q6GPH6 2 96325317-96330517 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Group enriched" "Detected in many" 10 "Early spermatids: 170.7;Late spermatids: 145.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 12.9" "Lineage enriched" "Detected in many" 5 "T-cells: 12.9" "Cell line enhanced" "Detected in many" "HEK 293: 30.9;HEL: 32.0;MOLT-4: 34.5;RPMI-8226: 33.0;U-698: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.26e-3)" "unprognostic (3.56e-3)" "unprognostic (4.78e-2)" "unprognostic (9.43e-2)" "unprognostic (2.22e-1)" "unprognostic (6.56e-4)" "unprognostic (3.04e-2)" "unprognostic (2.87e-1)" "unprognostic (6.50e-2)" "unprognostic (5.36e-2)" "unprognostic (8.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.41e-5)" "unprognostic (4.97e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (6.39e-2)" 3.4 0.4 0.5 2.9 1.0 1.1 3.8 3.2 0.7 0.9 0.3 0.9 1.2 0.5 0.5 1.5 0.8 1.6 1.3 0.5 0.5 0.5 0.5 1.4 3.9 0.9 0.5 0.4 1.4 0.5 0.4 1.2 0.8 2.0 0.9 0.9 7.5 1.5 1.5 0.8 1.7 1.0 0.6 2.6 1.2 27.8 0.6 5.1 0.7 2.0 4.2 1.5 1.2 0.8 0.0 0.0 7.3 0.1 0.8 1.9 8.3 1.6 8.7 7.2 14.1 3.3 0.3 0.0 0.1 3.1 0.1 0.7 25.4 0.0 8.1 15.7 30.9 32.0 0.2 14.4 3.9 0.1 0.0 5.4 0.0 8.3 0.0 0.0 4.7 20.4 0.0 10.6 0.2 0.0 34.5 5.0 10.5 0.0 0.0 22.7 23.1 33.0 0.3 0.0 21.2 14.2 0.0 0.0 0.1 4.4 0.0 5.3 2.4 0.0 0.8 0.1 0.1 15.4 21.4 35.3 4.1 0.0 6.8 0.4 0.2 0.0 10.2 0.2 12.9 1.6 3.3 9.7 1.2 0.4 0.7 4.1 0.1 2.7 0.0 0.5 6.3 2.3 0.5 1.0 3.2 0.7 0.5 0.5 0.9 0.5 0.8 0.6 0.6 0.8 9.4 3.2 0.0 0.0 2.3 0.3 4.8 1.8 2.2 0.7 3.6 2.9 0.7 2.8 3.5 0.0 4.2 0.9 6.9 1.0 0.0 0.1 170.7 0.2 0.6 2.7 0.0 1.7 0.2 0.2 2.3 0.9 0.5 0.1 0.0 0.8 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 2.4 145.2 1.2 1.8 1.8 0.0 0.3 4.3 11.3 0.0 0.0 0.3 0.1 0.7 7.6 3.3 0.0 0.3 0.8 1.7 6.6 0.6 2.9 3.6 2.8 1.7 1.0 0.4 14.8 0.3 0.4 1.3 JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.1;Basal respiratory cells: 30.9;Basal squamous epithelial cells: 27.3;Breast myoepithelial cells: 26.4;Endothelial cells: 34.2;Horizontal cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.6;HBEC3-KT: 21.0;SCLC-21H: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Supported Vesicles,Cytosol NA NA 370000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "CAB025481: , HPA030636: AB_10602607, HPA050567: AB_2681178" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (4.28e-2)" "unprognostic (6.97e-3)" "unprognostic (3.50e-1)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (9.19e-2)" "unprognostic (8.47e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.39e-1)" "unprognostic (2.17e-1)" 7.2 1.0 4.0 1.3 3.6 0.1 9.6 0.9 5.0 4.6 0.5 3.1 1.1 5.3 0.4 8.8 5.3 1.8 12.8 3.5 7.4 4.3 0.9 5.1 0.7 4.6 4.4 1.5 6.8 1.5 17.4 3.0 6.8 8.1 0.2 0.8 7.8 2.8 9.7 19.5 4.0 1.1 2.5 2.0 3.0 3.2 6.5 1.6 4.7 2.8 0.6 5.2 6.8 1.6 16.8 6.7 0.4 1.7 0.0 0.0 20.0 0.2 0.1 0.0 0.0 5.6 20.1 0.0 13.8 0.0 0.1 62.6 4.0 21.0 0.0 2.3 9.7 0.0 20.0 0.0 0.2 0.1 3.9 0.2 9.9 0.0 2.3 0.2 5.1 0.9 4.1 0.0 0.0 7.6 0.0 0.0 2.0 2.1 2.3 5.3 3.9 7.2 0.1 4.4 31.4 1.0 5.6 1.3 0.2 0.3 15.8 2.5 17.2 0.1 1.7 0.0 0.2 0.9 0.1 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.6 0.9 5.0 3.5 7.4 4.6 4.4 6.8 2.5 6.5 1.6 56.1 6.4 3.2 1.0 0.2 23.3 7.6 30.9 27.3 2.7 3.8 26.4 6.7 2.8 7.6 0.0 25.0 2.2 2.2 2.7 0.0 3.9 0.1 16.5 0.9 34.2 0.0 0.0 12.1 2.7 1.0 1.8 2.0 7.4 0.0 1.1 7.9 0.6 0.7 26.9 9.9 3.6 4.1 0.8 2.9 1.0 1.5 1.1 7.2 15.0 1.3 0.6 1.0 0.5 1.1 3.3 2.1 0.7 0.9 4.4 8.2 0.3 11.5 4.8 0.0 3.7 3.7 0.8 13.5 6.0 6.8 1.4 3.4 0.3 2.7 1.5 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LITAF "FLJ38636, PIG7, SIMPLE, TP53I7" ENSG00000189067 "Lipopolysaccharide induced TNF factor" Q99732 16 11547722-11636381 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 701.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 2578.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 2578.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006960 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Golgi apparatus, Vesicles" "HPA006960: AB_1079254" "unprognostic (2.26e-1)" "unprognostic (4.96e-2)" "unprognostic (2.32e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (4.07e-2)" "unprognostic (8.75e-3)" "unprognostic (3.60e-1)" "unprognostic (6.15e-3)" "unprognostic (1.04e-1)" "unprognostic (4.61e-2)" "unprognostic (5.01e-1)" "unprognostic (1.85e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.57e-2)" "unprognostic (1.60e-1)" 139.3 43.7 53.5 165.8 81.9 207.0 95.5 79.6 70.0 121.2 70.5 121.1 46.3 100.5 77.8 62.7 108.2 114.1 63.9 52.2 63.0 182.3 107.7 192.1 112.3 94.0 79.4 67.6 64.6 56.5 39.0 71.3 92.7 105.9 116.1 63.9 116.4 83.4 36.3 71.6 57.9 93.5 77.3 119.6 70.7 10.6 77.6 68.6 116.8 37.6 123.7 214.1 83.1 109.4 79.2 157.8 89.4 43.8 13.9 11.0 90.7 100.2 309.0 93.6 139.1 62.6 206.3 39.9 126.8 86.1 108.7 95.5 40.1 186.4 88.4 304.2 45.8 2.8 117.1 310.3 212.9 12.5 12.9 35.0 320.8 79.6 210.7 84.4 0.3 2.7 25.3 149.5 1.5 75.8 1.8 183.3 146.4 104.0 0.6 12.1 19.6 228.2 79.0 110.4 22.2 68.0 172.9 219.4 183.9 136.3 122.5 66.7 0.8 38.7 65.3 23.0 24.2 59.2 140.6 100.5 45.1 95.8 225.5 508.8 149.5 284.0 459.6 130.2 277.2 174.0 284.0 412.7 178.0 173.9 318.9 381.4 2578.1 274.5 81.9 220.1 350.3 584.9 53.5 81.9 79.6 70.0 52.2 63.0 94.0 79.4 92.7 77.3 77.6 109.4 297.5 44.8 70.0 7.5 176.7 157.4 336.2 365.4 68.3 2.2 180.5 157.6 48.8 148.7 222.2 163.7 0.0 56.4 505.5 305.4 485.2 245.8 2.3 112.2 151.9 76.3 17.5 18.3 1.1 72.9 471.9 156.7 39.8 108.1 214.9 1.1 94.2 52.9 227.8 0.0 1.6 153.1 175.0 156.9 701.0 11.3 56.2 422.0 156.5 7.5 391.8 232.7 433.5 11.6 59.5 123.3 236.1 68.4 186.3 239.8 23.3 104.3 150.3 5.4 52.6 89.6 176.1 0.2 5.4 37.1 132.1 37.1 278.7 16.6 88.9 368.6 LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.2;Endothelial cells: 144.6;Erythroid cells: 103.7;Hepatic stellate cells: 167.4;Kupffer cells: 65.0;Microglial cells: 64.6" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cell line enhanced" "Detected in some" "HEL: 71.8;HL-60: 72.7;K-562: 60.9;NB-4: 27.3;THP-1: 81.6;U-937: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" 15.0 5.9 14.9 11.4 13.0 27.7 12.5 14.2 16.6 8.4 13.4 5.0 4.6 6.5 0.7 6.8 8.3 5.4 4.4 14.7 16.0 13.1 2.3 18.2 19.4 19.9 16.3 3.5 2.6 2.3 8.6 6.5 18.5 5.7 1.5 0.6 5.3 2.4 23.4 4.9 6.6 4.8 18.7 19.0 3.9 1.7 19.0 1.8 12.3 4.6 8.4 5.8 7.3 13.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 2.2 1.3 12.8 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 71.8 0.0 0.0 0.3 72.7 18.5 0.0 0.0 0.0 0.0 0.0 10.2 0.0 60.9 0.0 0.0 0.3 5.1 27.3 0.9 0.0 0.0 15.3 0.8 0.2 0.0 0.8 4.3 0.0 0.3 0.5 0.1 0.2 0.0 81.6 0.9 0.0 0.2 1.7 0.0 0.0 0.2 0.6 4.7 29.2 0.3 0.6 0.5 1.5 0.0 1.4 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 1.7 0.1 0.0 0.2 14.9 13.0 14.2 16.6 14.7 16.0 19.9 16.3 18.5 18.7 19.0 13.3 109.2 3.2 7.1 8.5 6.6 8.4 7.9 8.0 0.6 1.6 2.8 9.5 2.8 8.6 1.7 5.5 2.1 0.4 1.0 0.8 0.0 3.0 0.5 40.5 11.0 144.6 0.0 103.7 1.3 2.0 3.2 9.8 0.0 39.6 7.6 0.9 167.4 1.7 39.1 0.0 3.8 0.2 2.0 65.0 56.8 1.2 4.1 54.1 10.6 64.6 47.5 1.1 4.1 5.0 1.0 1.0 1.9 0.0 3.0 5.4 0.0 8.8 5.0 2.6 0.0 17.3 3.6 0.3 7.9 0.8 6.0 21.5 1.9 12.4 0.5 25.1 LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 73.5;Excitatory neurons: 73.6;Inhibitory neurons: 99.2;Microglial cells: 185.5;Oligodendrocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.9;monocytes: 6.6;T-cells: 11.3" "Cell line enhanced" "Detected in many" "THP-1: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Approved "Golgi apparatus" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 28: Placenta - Pregnancy" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA029347: AB_10601544" "unprognostic (2.61e-2)" "unprognostic (3.09e-2)" "unprognostic (3.83e-2)" "unprognostic (1.76e-2)" "unprognostic (3.32e-2)" "unprognostic (1.65e-2)" "unprognostic (5.02e-2)" "unprognostic (3.76e-3)" "unprognostic (4.28e-2)" "unprognostic (4.90e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.78e-2)" "unprognostic (4.42e-2)" "unprognostic (1.94e-2)" "unprognostic (3.38e-2)" 14.3 7.6 3.8 9.0 4.5 8.0 7.7 4.5 5.8 3.2 11.4 3.2 3.2 7.3 1.9 2.9 2.8 6.6 6.2 4.1 4.1 2.5 3.3 7.7 12.2 4.6 5.0 5.3 1.8 2.8 2.3 6.6 5.1 2.3 3.7 1.6 2.0 2.0 2.7 6.0 3.8 15.8 4.8 9.2 2.9 4.0 4.7 5.6 3.5 8.0 7.7 6.2 2.0 6.0 0.3 3.8 3.0 2.7 9.1 10.2 1.4 19.3 21.6 8.7 8.0 0.0 1.3 6.0 5.3 8.5 14.9 13.1 10.1 29.0 20.9 14.8 6.1 5.7 2.9 0.3 7.4 26.6 1.9 4.4 5.8 18.8 10.0 5.8 35.6 9.2 3.9 7.9 7.5 0.7 3.9 26.2 3.3 0.1 7.8 26.5 1.4 2.0 1.8 3.2 2.3 10.7 7.1 0.7 16.2 4.7 0.2 41.3 29.9 15.3 7.3 5.3 14.9 2.9 2.6 3.1 4.7 19.6 2.6 0.4 6.0 0.0 3.8 5.2 3.3 0.7 6.1 5.1 8.9 0.5 4.8 4.5 0.8 2.0 6.6 0.7 11.3 3.2 3.8 4.5 4.5 5.8 4.1 4.1 4.6 5.0 5.1 4.8 4.7 6.0 73.5 3.2 3.6 31.3 7.6 45.4 3.8 5.6 3.4 2.3 1.7 2.9 6.3 2.8 2.7 0.0 0.0 0.1 24.6 0.3 0.0 1.7 36.3 0.2 1.9 47.3 1.2 4.8 73.6 2.4 1.1 8.7 2.6 0.6 0.0 58.5 28.9 0.1 13.6 1.7 99.2 0.3 2.0 29.5 36.9 21.3 0.0 27.8 26.6 185.5 21.3 0.5 13.4 22.1 85.2 12.8 1.9 0.7 20.8 2.1 0.3 0.6 2.9 1.2 0.0 2.2 24.2 3.9 2.0 1.3 44.9 0.3 27.1 3.4 0.3 2.5 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261716 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 279.7;tongue: 120.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.1;Astrocytes: 22.9;Endothelial cells: 15.8;Hepatic stellate cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 31.6" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: AB_2682524" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 11.0 2.3 15.6 3.8 16.5 1.3 7.9 15.5 21.2 11.4 9.2 4.7 3.5 19.0 9.8 6.3 11.2 4.4 15.7 15.1 16.5 10.7 1.4 6.8 4.1 17.1 14.9 10.6 1.8 4.3 25.1 4.1 14.6 10.0 1.1 1.4 4.3 6.9 279.7 1.5 4.4 8.6 14.6 4.3 5.0 4.6 15.2 0.9 3.2 120.9 1.4 6.0 5.9 13.9 23.2 13.9 5.3 16.3 12.4 13.5 7.5 17.5 15.1 28.2 18.3 19.6 7.2 45.1 23.4 19.6 16.8 15.4 24.3 3.4 5.5 12.8 34.0 29.2 46.7 24.9 37.7 28.4 54.5 29.8 6.0 7.2 0.0 16.8 33.2 4.0 26.3 38.5 13.4 12.8 0.0 35.4 15.9 7.6 22.5 41.4 14.2 43.9 17.5 3.0 18.0 6.5 13.3 0.5 22.1 4.2 7.1 29.6 18.7 28.5 26.1 6.6 11.2 9.3 7.3 24.5 7.2 24.7 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.6 16.5 15.5 21.2 15.1 16.5 17.1 14.9 14.6 14.6 15.2 13.9 23.1 0.0 3.2 22.9 1.6 0.8 0.7 3.3 1.2 5.5 1.2 1.3 8.8 4.3 0.8 0.0 0.0 0.3 0.9 0.3 1.9 0.5 0.3 0.6 10.0 15.8 1.8 1.7 9.8 0.0 2.8 5.3 2.6 0.7 10.8 0.6 20.7 0.9 6.3 1.7 6.5 0.2 8.2 2.2 0.8 1.9 6.5 2.2 0.0 6.5 0.6 8.1 0.0 5.0 0.9 0.5 0.0 3.8 2.8 3.6 0.4 8.0 0.9 2.2 6.6 3.3 3.0 0.7 12.1 0.8 0.6 0.4 2.2 3.2 0.3 0.2 MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 134.5" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Bipolar cells: 70.4;Cone photoreceptor cells: 127.2;Endothelial cells: 69.7;Microglial cells: 92.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 35.9;SCLC-21H: 65.3;SH-SY5Y: 29.0;SK-BR-3: 43.9;WM-115: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" 44.1 7.6 39.0 6.3 35.1 0.9 39.5 134.5 76.1 16.5 0.4 17.5 11.3 19.4 5.1 14.1 17.8 13.4 52.8 32.3 27.7 17.5 7.7 19.0 6.8 51.3 40.6 4.8 18.8 10.3 44.4 8.4 57.6 17.0 13.7 20.0 32.7 8.5 16.5 24.8 18.7 7.1 29.1 3.6 18.1 2.0 49.3 7.1 27.6 16.3 6.0 15.0 16.9 47.7 0.0 1.6 14.9 4.8 0.5 0.9 2.1 0.0 0.0 0.0 0.0 3.8 2.2 0.1 3.7 1.5 2.5 0.3 3.8 0.0 0.0 0.0 7.4 4.3 0.2 9.1 0.5 0.2 3.1 1.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.2 14.4 5.6 0.5 2.6 4.0 35.9 0.0 0.2 15.0 7.9 5.9 23.6 65.3 29.0 0.0 43.9 0.1 2.4 26.0 0.1 0.6 0.1 12.5 5.4 0.0 7.5 0.4 2.3 23.9 1.0 60.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.4 39.0 35.1 134.5 76.1 32.3 27.7 51.3 40.6 57.6 29.1 49.3 47.7 138.3 0.0 8.4 4.6 2.6 5.5 3.4 1.5 8.0 70.4 12.9 10.0 44.3 12.8 4.6 9.2 127.2 0.0 1.2 10.8 7.9 5.6 0.4 9.9 1.6 69.7 26.5 0.0 58.5 2.6 0.2 7.1 23.0 18.7 1.3 11.2 13.6 3.4 1.4 38.7 60.9 54.6 8.2 2.2 4.6 1.5 0.6 2.5 8.8 92.8 0.1 5.4 0.0 40.7 75.0 1.7 9.8 1.2 3.0 4.2 4.0 10.4 7.2 23.9 0.0 5.2 11.9 0.7 2.7 4.2 9.1 0.1 2.1 0.5 7.4 4.1 MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.0;breast: 26.1;heart muscle: 24.9" "Group enriched" "Detected in some" 9 "Adipocytes: 63.5;Endothelial cells: 41.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Cell line enriched" "Detected in some" 14 "HeLa: 25.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: AB_10959299, HPA063788: " "unprognostic (1.36e-3)" "unprognostic (2.15e-4)" "unprognostic (1.25e-1)" "unprognostic (2.58e-3)" "unprognostic (2.01e-2)" "unprognostic (5.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-3)" "unprognostic (6.71e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (9.36e-2)" "unprognostic (3.44e-6)" "unprognostic (2.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.82e-1)" "unprognostic (7.47e-3)" 36.0 0.5 0.0 4.7 0.0 0.0 26.1 0.0 0.1 8.0 0.0 4.7 1.6 5.5 1.1 3.7 9.0 5.7 24.9 0.0 0.0 0.2 0.1 1.4 6.6 0.0 0.0 1.0 1.5 1.2 0.5 0.1 0.0 2.6 2.4 0.0 4.9 1.9 8.3 6.6 5.1 10.6 0.0 10.8 3.0 1.1 0.0 3.0 1.9 17.1 5.3 7.7 7.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 1.8 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.1 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.3 2.7 0.0 0.0 1.7 0.5 0.0 0.3 0.0 0.0 17.5 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.5 0.0 0.0 1.0 0.3 4.1 0.0 0.0 1.2 0.0 0.4 0.6 2.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 41.3 0.0 0.0 0.7 0.0 0.3 4.8 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 1.0 0.0 0.1 0.3 1.8 0.1 1.5 0.3 0.0 0.0 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Endothelial cells: 25.9;granulocytes: 29.1;Macrophages: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 20.0 7.1 8.4 20.3 8.7 30.7 12.1 8.6 12.7 9.0 9.6 11.0 11.0 6.0 2.0 15.6 8.0 11.5 10.6 7.8 8.2 15.4 9.3 25.6 15.4 10.1 9.8 3.0 9.9 1.6 3.7 9.2 9.3 8.4 11.4 0.3 13.3 4.3 3.1 4.9 14.4 7.6 9.1 36.1 10.8 1.2 10.3 6.7 8.7 3.1 13.8 12.3 11.5 9.6 13.5 24.4 0.1 0.1 6.0 12.4 0.2 17.0 14.8 15.4 22.4 13.9 26.6 0.3 19.1 14.2 13.7 21.7 4.3 24.9 5.8 8.3 0.6 18.8 17.6 16.2 4.2 12.3 18.6 8.5 2.4 16.8 5.7 9.0 37.3 21.3 2.7 2.5 11.9 22.0 7.0 24.3 2.2 29.3 30.0 13.5 1.8 23.8 22.0 10.2 1.0 0.8 13.4 8.7 7.2 0.1 6.2 12.5 41.4 7.8 4.8 7.0 11.7 11.2 40.2 3.2 13.7 42.3 3.9 21.9 36.2 45.8 11.2 22.2 15.4 8.1 12.6 12.0 18.9 6.7 6.8 10.4 48.6 3.6 23.3 1.2 17.4 16.0 8.4 8.7 8.6 12.7 7.8 8.2 10.1 9.8 9.3 9.1 10.3 9.6 32.1 3.2 10.7 1.0 9.8 3.4 6.8 3.1 7.4 0.2 3.3 3.4 3.1 2.8 5.5 1.8 0.0 0.2 9.6 8.9 1.9 4.6 3.5 1.2 1.9 25.9 1.2 3.4 0.5 5.2 0.8 7.1 15.3 1.6 29.1 0.3 16.8 1.3 16.6 1.7 0.5 10.9 0.0 18.2 7.8 5.2 0.9 28.9 7.2 11.2 16.7 0.1 11.3 1.5 5.2 4.9 9.4 0.4 18.5 2.8 5.5 0.6 2.0 0.6 0.0 3.0 3.1 0.1 0.2 13.4 2.8 0.3 16.5 0.2 9.5 7.5 MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 332.5;Basal prostatic cells: 504.4;Basal respiratory cells: 289.1;Squamous epithelial cells: 336.4;Suprabasal keratinocytes: 467.4;Urothelial cells: 489.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 120.9;EFO-21: 130.4;HaCaT: 166.9;RT4: 321.7;TIME: 351.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" 28.6 4.7 2.5 11.9 2.1 0.7 19.6 2.3 4.8 56.7 5.2 31.1 17.0 16.9 38.5 222.5 46.4 33.5 7.2 2.3 2.6 26.4 23.2 47.0 2.3 3.2 3.0 3.8 13.5 27.1 10.7 1.7 3.2 48.6 30.8 0.9 58.0 69.5 4.7 38.8 11.3 14.7 3.6 4.6 37.0 0.9 3.4 18.1 30.3 1.0 52.6 155.9 120.5 2.8 65.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 27.0 120.9 0.3 130.4 0.0 0.6 166.9 0.0 38.9 0.0 0.2 9.5 0.1 1.7 35.8 0.0 0.0 0.4 0.0 90.2 0.0 3.0 0.0 86.8 0.8 0.0 0.2 0.0 51.3 0.2 0.2 1.6 34.2 0.1 0.0 0.0 6.4 14.9 321.7 0.1 0.0 5.8 61.4 0.0 0.5 26.1 0.7 351.9 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 2.3 11.6 3.0 0.1 9.2 1.3 0.0 0.6 0.4 17.0 0.0 0.8 0.9 13.2 0.4 1.4 0.3 0.2 3.8 2.5 2.1 2.3 4.8 2.3 2.6 3.2 3.0 3.2 3.6 3.4 2.8 5.9 83.3 123.3 0.0 0.2 332.5 504.4 289.1 127.5 0.0 29.0 17.4 3.4 30.0 221.1 128.8 0.0 1.7 0.5 52.0 0.0 39.4 0.0 91.6 18.8 33.6 5.3 3.6 0.0 51.1 0.2 8.2 29.6 194.0 7.0 0.0 45.3 16.5 0.8 0.0 0.0 6.3 81.4 6.4 27.0 0.3 0.0 7.8 21.4 1.9 4.9 0.0 1.0 0.0 0.0 68.2 20.8 0.0 1.2 186.3 3.3 6.9 65.2 0.0 0.0 0.3 9.2 0.2 0.7 336.4 467.4 17.8 5.4 0.0 33.4 489.7 MRTFB "FLJ31823, MKL2, MRTF-B" ENSG00000186260 "Myocardin related transcription factor B" Q9ULH7 16 14071319-14266773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 43.9;Cardiomyocytes: 26.9;Cytotrophoblasts: 9.9;Endothelial cells: 9.6;Extravillous trophoblasts: 10.0;Smooth muscle cells: 14.9;Syncytiotrophoblasts: 10.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 170 "amygdala: 9.4;basal ganglia: 15.1;cerebral cortex: 21.4;hippocampal formation: 21.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011286 Enhanced Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA011286: AB_1853973" "unprognostic (2.00e-1)" "unprognostic (5.28e-1)" "unprognostic (1.30e-2)" "unprognostic (3.62e-1)" "unprognostic (7.16e-2)" "unprognostic (7.14e-3)" "unprognostic (1.21e-1)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-1)" "unprognostic (3.19e-1)" "unprognostic (2.32e-1)" "prognostic favorable (6.20e-4)" "unprognostic (5.22e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (5.96e-2)" 21.4 7.3 9.4 8.6 15.1 3.8 18.3 0.0 21.4 19.0 0.0 9.9 9.7 14.9 9.1 14.5 14.0 13.3 11.8 21.7 0.0 8.4 5.9 13.2 7.6 0.0 0.0 7.1 12.1 22.2 4.9 21.7 0.0 15.5 10.8 8.6 11.6 15.2 11.9 16.6 7.9 15.6 0.0 5.1 10.1 17.5 0.0 10.3 16.9 14.5 8.1 11.3 12.2 0.0 17.6 17.8 17.8 13.2 5.9 11.0 8.0 4.9 13.3 7.4 10.6 7.7 16.4 9.4 12.4 8.4 9.3 13.8 12.9 14.4 13.5 23.1 7.0 6.0 13.6 13.3 8.2 4.2 5.4 8.4 14.6 12.8 8.3 7.8 14.7 12.2 7.9 9.7 5.6 15.1 13.4 2.8 6.0 4.7 4.8 20.5 13.7 8.1 7.3 17.3 6.2 10.8 23.9 10.2 4.9 8.2 18.0 3.5 9.4 15.3 14.9 4.4 6.4 6.6 8.8 8.4 16.6 7.1 11.7 0.2 0.5 0.0 1.1 0.7 1.7 3.7 1.9 0.9 0.7 1.5 2.4 1.3 0.3 1.1 0.8 1.7 0.9 0.6 9.4 15.1 0.0 21.4 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 9.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 10.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 10.4 0.4 0.0 0.0 0.0 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 613.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 571.9;Distal enterocytes: 405.4;Horizontal cells: 588.9;Suprabasal keratinocytes: 667.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 606.9;hTERT-HME1: 1226.9;U-87 MG: 772.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" 161.2 72.9 299.1 55.9 523.6 130.0 107.6 413.5 300.2 169.4 132.8 130.0 242.2 92.9 34.3 343.1 106.4 87.8 99.8 254.5 316.6 192.4 49.6 116.6 38.7 523.2 500.0 126.1 52.8 69.1 82.2 110.8 476.8 354.3 77.8 86.0 130.8 60.0 28.2 262.6 258.1 61.9 333.7 39.4 154.0 28.1 423.1 55.1 80.5 44.6 88.1 105.5 273.8 613.9 191.6 24.0 1.7 0.8 116.3 86.8 26.0 13.7 103.0 9.8 52.5 12.5 27.6 1.5 133.0 58.0 21.9 62.4 1.7 316.8 18.0 13.3 226.8 1.9 55.6 14.7 46.3 7.0 4.6 79.2 606.9 51.2 1226.9 124.2 45.2 27.9 2.0 138.3 17.2 11.0 19.1 20.8 3.0 69.8 155.8 1.7 19.4 86.2 29.7 28.0 13.8 13.0 31.0 312.1 73.3 48.6 1.3 20.0 58.5 84.4 43.6 40.7 10.4 96.3 280.3 0.8 772.5 69.5 161.5 10.9 4.3 0.0 5.8 3.4 9.1 1.6 5.3 6.9 6.0 1.4 3.9 3.1 4.0 1.5 4.2 13.0 8.1 3.7 299.1 523.6 413.5 300.2 254.5 316.6 523.2 500.0 476.8 333.7 423.1 613.9 123.0 144.2 47.4 14.4 23.6 571.9 141.3 207.3 42.1 68.8 28.6 31.2 20.6 80.1 102.9 187.6 2.1 12.8 68.1 405.4 33.2 33.2 5.3 57.4 59.0 217.7 22.1 17.4 7.7 13.7 138.2 90.5 151.4 167.7 22.2 41.0 112.8 64.0 16.5 588.9 5.7 140.9 83.4 31.1 109.5 5.9 49.0 42.7 101.4 28.1 25.7 81.2 14.4 20.6 136.2 62.9 155.9 44.0 23.5 264.3 402.5 87.5 38.7 40.3 46.0 65.2 44.3 1.2 7.1 113.0 667.4 43.4 45.7 32.6 124.7 280.8 NECTIN2 "CD112, HVEB, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 136.6;Ductal cells: 215.6;Exocrine glandular cells: 154.2;Glandular and luminal cells: 126.1;Pancreatic endocrine cells: 241.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012759, CAB026138, HPA073459" Enhanced Approved "Nucleoli fibrillar center,Cell Junctions" NA Yes 5900000 "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoli fibrillar center, Cell Junctions" "CAB026138: , HPA012759: AB_1846227, HPA073459: " "unprognostic (3.30e-2)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" "unprognostic (6.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.97e-1)" "unprognostic (6.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-2)" "unprognostic (2.05e-1)" 71.4 79.1 30.8 32.1 28.4 15.8 66.0 29.8 34.3 41.7 44.3 42.3 55.3 45.0 58.2 76.3 43.9 52.5 71.3 29.2 33.1 79.6 118.5 72.9 15.8 35.8 33.0 41.7 55.0 61.5 39.1 77.2 32.9 69.2 32.8 16.7 62.6 30.4 20.1 52.5 47.5 31.3 31.8 58.1 75.4 65.8 34.7 6.9 57.4 17.7 25.3 55.8 49.3 28.9 73.8 89.3 118.3 140.6 59.3 35.8 123.7 62.6 83.9 120.4 136.6 194.8 171.0 0.6 79.2 79.0 61.1 98.5 106.6 55.6 91.7 3.2 53.2 43.0 30.8 128.6 145.0 0.7 117.9 64.9 22.5 56.2 44.8 123.2 149.3 3.0 71.1 0.7 59.2 146.4 0.6 5.6 92.8 249.8 27.7 4.3 37.7 3.2 139.5 100.1 5.4 15.2 74.9 127.0 28.7 210.4 97.2 47.1 140.1 31.3 105.5 23.7 48.6 9.0 25.8 0.6 57.3 10.0 83.0 1.8 2.0 10.4 0.0 0.7 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 0.0 0.4 0.3 0.0 0.7 30.8 28.4 29.8 34.3 29.2 33.1 35.8 33.0 32.9 31.8 34.7 28.9 136.6 35.3 31.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 108.4 54.9 0.0 0.0 6.8 58.8 0.0 109.3 2.6 0.0 3.9 215.6 0.0 73.8 66.3 58.8 0.0 0.0 0.0 154.2 97.8 30.4 0.0 126.1 3.8 75.0 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 80.1 0.0 0.0 0.0 0.0 241.8 0.0 0.0 0.1 0.0 0.0 27.1 3.6 0.0 0.0 0.0 42.9 0.0 0.0 0.0 0.0 101.8 2.2 58.3 0.0 0.0 NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Microglial cells: 26.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA074367: AB_2686683" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (9.73e-2)" "unprognostic (8.09e-3)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-3)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.68e-4)" "unprognostic (6.62e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.95e-4)" "unprognostic (2.64e-1)" 10.6 2.9 3.0 8.8 3.2 6.8 9.5 2.5 2.6 5.3 4.6 5.3 2.2 6.1 2.6 4.7 6.5 5.4 7.3 2.4 3.2 3.9 2.2 11.9 6.1 7.6 4.9 10.3 1.8 2.7 2.9 12.2 4.7 4.0 4.3 0.6 6.2 3.2 4.0 5.9 5.4 7.3 3.6 11.1 4.8 1.9 5.6 3.5 10.8 4.0 5.0 7.3 5.0 2.8 4.8 2.5 3.5 10.5 2.2 10.3 5.3 3.3 2.3 5.5 7.0 2.2 5.7 6.9 3.8 4.2 6.1 11.2 3.5 5.8 3.7 3.6 3.0 9.7 7.7 2.2 2.8 4.3 7.0 9.6 2.5 3.5 3.0 4.9 18.3 10.1 5.2 2.4 5.0 2.8 6.2 7.7 4.1 5.3 4.5 7.4 4.0 6.3 1.8 3.8 0.6 12.4 4.2 10.7 3.7 4.8 3.6 9.6 7.7 4.8 7.6 6.0 4.5 2.2 8.0 0.3 3.5 15.1 5.1 13.7 3.7 13.5 8.1 5.0 8.9 7.5 5.5 5.3 3.3 10.9 4.9 4.0 2.8 8.5 6.6 8.0 4.8 2.6 3.0 3.2 2.5 2.6 2.4 3.2 7.6 4.9 4.7 3.6 5.6 2.8 19.3 3.2 15.1 7.2 6.6 0.8 0.5 1.0 5.2 2.4 2.9 2.9 4.9 1.5 5.0 5.5 0.0 5.0 6.7 4.5 0.0 1.3 0.2 4.4 1.7 12.0 0.0 3.4 5.3 2.1 2.3 8.2 1.1 4.6 2.5 7.8 13.6 1.3 4.6 0.0 1.4 5.5 2.0 3.1 3.7 0.0 0.6 4.3 5.4 26.2 4.0 0.6 6.2 2.5 1.1 1.7 1.7 1.9 3.1 0.2 1.6 0.5 2.9 0.2 0.0 2.5 5.6 0.0 0.6 5.4 1.8 1.5 5.3 1.0 5.6 0.8 NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 167.0;Endothelial cells: 129.6;Hepatic stellate cells: 172.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 10.1;HEL: 41.9;K-562: 31.8;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA044384: AB_2678922, HPA076885: " "unprognostic (4.74e-2)" "unprognostic (2.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.27e-1)" "unprognostic (3.15e-3)" "unprognostic (3.02e-6)" "unprognostic (4.89e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-4)" "unprognostic (5.47e-3)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (6.47e-2)" "unprognostic (4.98e-2)" 32.6 20.4 6.1 4.6 5.8 0.3 31.4 5.0 7.6 17.5 4.2 15.3 14.0 14.9 4.3 5.1 16.4 14.0 16.1 4.9 5.6 32.6 7.3 30.8 4.6 6.6 6.0 10.6 22.6 3.8 3.8 25.4 6.5 13.3 16.4 0.8 48.9 6.8 5.1 7.3 14.3 12.8 5.5 5.5 23.0 14.4 6.6 1.9 13.5 3.6 3.0 8.1 11.3 5.0 0.0 3.6 1.1 0.0 0.0 0.0 10.1 0.4 0.0 0.0 0.0 6.3 6.5 0.1 4.3 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 41.9 1.8 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 31.8 0.0 0.0 0.1 0.1 0.1 0.1 20.5 0.3 0.4 1.9 0.0 3.4 1.6 0.0 0.1 0.2 1.9 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.2 0.6 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 5.0 7.6 4.9 5.6 6.6 6.0 6.5 5.5 6.6 5.0 167.0 9.6 10.3 2.0 1.6 1.0 0.6 0.3 0.6 0.1 20.0 11.0 7.1 15.7 3.3 3.7 0.0 18.9 0.4 57.3 13.7 8.0 26.6 16.3 3.3 129.6 11.4 2.7 0.4 21.8 7.0 6.1 41.3 23.2 0.0 72.4 172.5 1.0 1.6 0.0 0.5 35.9 0.0 6.3 0.9 60.9 8.7 1.2 24.9 55.3 0.7 1.6 0.0 2.0 0.0 17.7 53.4 5.7 0.2 3.3 43.1 59.0 1.5 0.3 72.3 1.3 11.3 13.7 1.8 0.4 0.4 26.3 0.9 71.9 20.7 1.2 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 NUAK1 "ARK5, KIAA0537" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063345-106138954 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.7;Excitatory neurons: 150.5;Hepatic stellate cells: 136.3;Microglial cells: 93.7;Oligodendrocytes: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 58.0;EFO-21: 55.1;RH-30: 77.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: AB_2683349" "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavorable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 17.5 3.6 12.6 2.3 17.5 0.6 12.1 9.4 25.4 9.8 0.0 4.1 2.2 9.5 3.1 3.5 9.0 4.9 18.8 17.4 5.6 4.2 4.0 9.3 3.2 6.1 5.9 6.1 3.2 17.5 2.7 4.5 8.3 6.0 3.9 5.4 3.4 6.0 20.6 20.8 4.3 10.2 5.5 0.8 3.8 2.6 5.5 3.3 4.3 17.2 2.3 4.8 8.1 31.8 13.0 8.3 58.0 0.6 23.7 2.5 27.0 14.2 9.5 9.9 8.0 4.3 2.1 0.0 55.1 27.4 5.0 11.9 12.6 11.2 4.8 0.2 3.4 0.0 9.7 4.7 5.0 0.1 0.1 11.0 8.1 6.0 1.7 19.2 21.2 0.1 0.0 40.3 7.8 1.3 0.2 0.6 11.1 0.2 3.3 0.1 77.7 10.5 6.6 13.3 6.8 0.4 6.9 1.9 0.5 37.2 2.9 0.4 16.6 9.4 29.7 3.3 17.0 0.0 0.0 0.7 2.8 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.6 17.5 9.4 25.4 17.4 5.6 6.1 5.9 8.3 5.5 5.5 31.8 56.4 0.0 2.4 15.7 0.6 13.5 32.9 29.8 10.2 32.3 2.1 4.2 48.9 10.0 7.2 7.3 0.0 0.8 13.5 0.9 3.9 6.2 0.4 5.1 6.6 111.7 0.0 5.3 150.5 9.6 5.2 17.9 2.0 3.8 0.0 2.9 136.3 12.1 8.0 40.4 55.4 2.3 12.2 8.4 8.8 2.6 4.1 1.3 10.6 93.7 0.6 1.9 1.0 15.6 73.5 18.4 0.5 3.0 3.2 10.6 0.2 1.8 2.2 2.9 0.0 7.1 26.4 1.0 5.5 2.5 15.9 0.3 2.7 0.4 0.8 5.2 NUDCD1 "CML66, FLJ14991" ENSG00000120526 "NudC domain containing 1" Q96RS6 8 109240919-109334121 "Predicted intracellular proteins" Immunity "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023183 Uncertain Supported Nucleoplasm,Cytosol NA NA 7300 "Cluster 39: Non-specific - mRNA processing" "Cluster 28: Placenta - Pregnancy" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA023183: AB_1854695" "unprognostic (5.08e-3)" "unprognostic (3.73e-2)" "unprognostic (2.52e-2)" "unprognostic (9.03e-3)" "unprognostic (7.52e-2)" "unprognostic (3.62e-3)" "prognostic unfavorable (1.39e-5)" "prognostic unfavorable (4.37e-5)" "unprognostic (2.13e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (8.22e-2)" "prognostic unfavorable (8.71e-6)" "unprognostic (1.95e-1)" "unprognostic (1.63e-1)" "unprognostic (3.35e-1)" "unprognostic (1.65e-1)" 11.1 5.0 3.3 6.0 3.5 1.3 9.5 3.7 4.2 7.7 3.1 5.5 2.8 7.2 5.2 5.7 6.9 4.8 6.6 3.3 3.5 7.8 6.4 7.0 9.3 3.7 3.6 6.3 6.9 5.8 4.2 15.1 3.4 5.9 6.7 4.7 6.1 6.8 6.1 4.3 5.1 7.9 4.1 7.3 5.8 13.0 3.4 10.1 9.0 9.3 8.5 11.4 6.8 3.8 28.9 16.7 24.7 13.7 13.1 18.0 13.1 20.6 24.8 57.8 54.4 17.6 21.8 18.5 13.1 22.5 16.3 17.1 36.3 34.3 79.8 23.6 12.6 28.8 9.9 19.6 27.2 13.7 10.6 12.7 18.4 28.1 40.3 18.3 53.0 22.7 32.2 9.5 49.5 23.3 33.3 15.1 17.3 59.7 22.7 21.4 20.4 18.3 35.6 14.8 20.5 18.1 9.4 26.1 21.6 25.6 19.2 9.9 14.2 28.2 17.2 12.1 17.6 6.9 9.4 22.3 10.4 22.2 24.1 0.0 0.4 0.5 0.8 1.3 1.4 1.2 1.0 1.6 1.4 1.1 1.1 1.6 0.0 1.7 1.7 0.9 1.5 0.7 3.3 3.5 3.7 4.2 3.3 3.5 3.7 3.6 3.4 4.1 3.4 3.8 25.4 3.2 10.0 6.2 11.3 17.7 24.4 19.4 10.2 5.0 7.4 6.3 11.3 2.8 23.2 3.7 6.2 23.4 9.7 2.5 7.9 17.1 122.3 11.2 19.2 26.5 9.0 14.5 22.9 11.0 21.2 16.2 5.6 10.2 17.7 11.8 8.9 6.2 9.8 5.0 23.5 5.7 14.2 4.7 11.5 22.5 13.1 8.7 7.2 13.1 16.9 4.4 5.2 15.1 15.3 14.1 4.7 6.8 12.1 29.6 3.4 13.0 15.4 9.0 0.0 13.7 15.8 53.3 36.4 8.9 16.8 8.2 9.5 12.5 9.9 22.7 OSTF1 "bA235O14.1, OSF, SH3P2" ENSG00000134996 "Osteoclast stimulating factor 1" Q92882 9 75088514-75147265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 329.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 302.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020514 Approved Supported Cytosol NA NA 580000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA020514: AB_2670461" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (7.54e-2)" "prognostic favorable (3.67e-5)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-3)" "unprognostic (3.76e-1)" "unprognostic (7.89e-2)" "unprognostic (6.36e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" 44.3 36.9 27.8 65.7 35.0 56.3 34.9 32.0 37.2 34.1 25.4 42.5 38.2 22.7 38.2 104.8 20.0 42.8 32.0 28.3 33.2 34.6 57.7 56.4 74.9 31.0 32.5 16.0 19.4 72.1 19.1 69.9 33.1 22.7 45.8 12.3 38.5 19.6 9.5 63.1 47.8 28.8 30.8 87.0 40.6 18.0 31.0 47.8 29.0 16.0 85.0 55.3 53.9 35.1 69.1 16.0 7.7 11.2 45.4 41.7 81.3 71.9 46.9 26.9 24.4 8.2 50.8 70.9 35.3 59.2 34.6 111.8 12.9 51.9 77.0 302.0 16.0 39.3 24.8 42.5 36.7 71.5 141.6 29.1 49.2 31.6 21.8 23.7 91.2 59.4 13.4 158.4 65.4 35.9 107.5 44.8 14.5 161.5 30.8 20.1 52.3 63.0 57.0 97.1 6.5 0.6 53.1 74.1 36.2 58.2 97.4 79.9 86.4 55.8 19.4 108.3 30.8 30.1 52.5 26.7 67.1 81.9 46.4 359.5 177.7 464.8 158.6 199.3 169.6 101.2 110.5 131.5 148.7 87.4 62.1 109.8 495.2 168.4 256.8 110.6 163.0 283.0 27.8 35.0 32.0 37.2 28.3 33.2 31.0 32.5 33.1 30.8 31.0 35.1 113.4 22.4 24.4 8.1 90.8 82.2 61.2 78.2 61.5 2.9 38.6 23.2 7.8 28.6 51.2 33.1 6.2 125.5 162.1 64.8 76.3 49.7 11.9 42.8 59.4 60.5 27.2 23.3 32.0 52.3 252.9 42.1 31.1 51.1 137.6 4.2 71.7 32.2 233.1 10.1 12.6 31.9 69.2 167.4 181.5 6.0 23.9 155.7 76.5 43.1 329.9 6.0 268.8 30.2 67.3 60.5 97.7 15.4 83.2 34.1 64.1 63.0 27.3 8.6 19.7 15.9 45.0 6.7 17.8 141.4 114.5 133.9 163.8 37.6 38.2 91.6 PDE4B DPDE4 ENSG00000184588 "Phosphodiesterase 4B" Q07343 1 65792514-66374579 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 75.5;brain: 109.1" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 1722.6;Oligodendrocytes: 4039.6" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 88.9" "Group enriched" "Detected in all" 5 "B-cells: 37.4;granulocytes: 88.9;T-cells: 34.7" "Cell line enhanced" "Detected in many" "AN3-CA: 61.8;HUVEC TERT2: 93.2;NTERA-2: 56.1;SK-MEL-30: 58.6;TIME: 52.6;U-266/84: 51.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003005 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" Cytosol "HPA003005: AB_1079587" "unprognostic (7.86e-2)" "unprognostic (3.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.90e-1)" "unprognostic (3.21e-1)" "unprognostic (3.33e-3)" "unprognostic (1.35e-1)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (6.10e-2)" "unprognostic (8.78e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (5.04e-4)" "unprognostic (2.89e-2)" "unprognostic (3.54e-1)" "unprognostic (9.04e-3)" "unprognostic (8.33e-3)" 18.3 3.1 40.1 39.5 82.5 75.5 20.0 63.3 53.5 7.2 1.6 8.3 4.6 8.3 1.1 4.5 4.2 10.1 21.4 45.7 68.4 5.4 10.9 14.7 23.2 85.9 74.4 2.1 1.6 1.4 3.8 17.2 78.5 23.0 10.5 14.1 21.1 12.1 44.3 8.9 12.2 12.4 66.4 22.6 5.1 3.8 62.9 14.0 7.2 15.0 19.9 32.1 4.6 109.1 0.2 18.5 34.7 61.8 1.6 1.7 0.1 11.5 13.3 10.1 13.4 0.0 0.0 5.3 0.2 20.7 0.4 0.1 0.3 0.0 9.7 15.5 0.1 0.3 5.2 0.0 1.2 13.1 0.0 3.4 0.5 4.5 0.2 1.6 93.2 0.0 0.0 3.3 4.7 0.3 0.0 7.5 56.1 0.0 0.7 2.6 6.2 3.6 8.7 0.0 0.2 26.6 0.0 3.0 58.6 2.9 0.2 4.5 52.6 7.2 1.9 4.6 1.9 1.5 51.6 19.3 8.6 13.4 3.7 10.8 6.8 22.0 10.1 5.8 19.5 36.8 19.4 14.8 6.2 37.4 21.3 15.0 88.9 11.3 5.7 6.4 34.7 9.6 40.1 82.5 63.3 53.5 45.7 68.4 85.9 74.4 78.5 66.4 62.9 109.1 24.7 9.6 12.2 531.8 233.3 20.3 28.4 0.5 27.9 40.9 51.6 34.3 25.4 0.0 6.9 5.5 0.0 7.3 79.8 0.4 0.0 0.8 14.4 1.7 14.9 36.8 4.2 0.0 315.6 0.9 2.0 20.2 9.7 4.2 15.2 0.2 11.7 2.4 13.0 114.4 559.7 1.9 8.2 40.6 187.4 9.4 0.3 176.9 51.6 173.3 67.0 19.3 1.0 1722.6 4039.6 0.1 0.4 2.6 351.9 93.6 0.0 2.1 1.5 4.0 0.0 54.0 10.3 0.7 0.8 4.8 8.1 5.6 143.1 0.4 1.3 9.4 PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 80.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA 4700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" 17.9 23.6 0.3 15.2 0.3 17.9 13.8 0.2 1.4 14.5 2.7 20.1 13.9 12.4 30.2 6.1 14.0 19.6 9.9 0.6 0.8 14.5 80.2 17.7 11.1 0.5 0.6 11.5 26.6 10.7 12.7 47.4 0.4 32.3 25.0 4.2 13.7 7.9 4.2 8.8 12.8 17.0 0.3 10.1 33.4 15.3 0.9 4.5 30.8 4.3 12.0 17.9 9.5 0.7 24.0 14.6 17.7 21.5 80.3 71.9 95.0 44.9 74.5 24.5 66.9 47.8 21.6 0.0 57.6 69.9 15.7 12.5 7.8 27.4 25.7 1.1 8.8 10.4 3.9 56.7 33.2 26.5 1.4 62.3 40.2 16.6 34.5 26.1 84.0 10.1 13.6 60.4 16.9 29.6 7.2 31.3 13.1 54.5 15.6 6.7 13.0 67.5 20.7 13.9 19.3 11.4 22.0 24.0 40.4 28.7 21.4 32.3 47.2 6.2 19.5 29.4 12.3 18.1 5.0 10.8 20.2 21.0 21.5 0.0 9.3 0.3 1.4 2.4 2.3 3.5 1.0 0.8 5.5 1.1 0.6 0.6 0.2 0.5 0.5 12.8 0.0 2.3 0.3 0.3 0.2 1.4 0.6 0.8 0.5 0.6 0.4 0.3 0.9 0.7 17.2 19.2 30.7 2.6 5.6 5.0 6.0 6.4 3.4 13.1 6.9 4.7 2.7 35.8 11.3 5.5 39.6 41.8 3.1 5.4 0.0 32.2 1.6 5.4 13.1 24.3 8.4 5.5 9.6 28.6 133.6 20.7 30.5 21.1 3.8 7.3 37.5 50.1 12.1 0.0 7.1 36.9 0.0 7.8 5.5 2.0 24.2 4.4 8.8 5.6 5.0 2.3 0.0 1.0 2.5 11.9 7.6 22.2 40.1 18.1 3.5 5.3 6.4 28.4 13.1 3.6 17.6 1.3 1.5 3.4 4.1 50.2 3.1 23.3 15.1 4.5 PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916434 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.6;Endothelial cells: 30.6;Hepatic stellate cells: 40.0;Leydig cells: 44.4;Peritubular cells: 35.7;Sertoli cells: 26.3;Smooth muscle cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.5;HBEC3-KT: 29.9;HHSteC: 21.6;HUVEC TERT2: 52.2;TIME: 85.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA 62000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cell Junctions" Centrosome "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" 19.0 5.0 2.5 2.3 3.0 2.3 12.9 1.2 4.1 12.3 2.0 4.5 1.6 10.0 1.1 2.6 9.1 7.4 8.7 1.2 1.7 4.8 2.1 11.8 3.8 2.0 2.3 9.1 2.3 1.7 3.4 11.7 2.3 4.7 0.9 0.4 2.9 3.7 5.7 4.2 4.1 4.6 1.1 7.0 3.7 3.0 2.9 1.4 9.7 7.6 1.1 6.0 7.3 1.4 0.5 2.9 0.8 0.0 0.0 3.7 0.1 11.7 19.5 4.8 2.8 0.3 0.5 0.0 0.6 8.7 0.4 0.2 0.0 29.9 1.3 0.2 0.0 14.8 0.7 0.8 21.6 0.1 0.0 11.3 0.1 6.5 1.5 1.0 52.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 6.9 0.0 0.0 85.2 0.1 6.4 2.6 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 3.0 1.2 4.1 1.2 1.7 2.0 2.3 2.3 1.1 2.9 1.4 44.6 0.0 3.2 0.0 0.4 0.9 0.1 0.7 1.2 2.4 0.6 1.3 7.5 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.2 0.2 2.5 30.6 1.8 5.7 0.0 0.4 0.1 10.1 1.5 0.4 1.3 0.1 40.0 0.4 0.5 0.0 0.0 2.3 0.0 1.6 1.5 3.5 44.4 3.0 5.4 12.2 0.4 0.2 0.0 0.0 0.0 1.2 0.0 35.7 0.0 0.2 0.0 0.1 0.2 0.2 26.3 1.7 34.2 1.5 1.5 0.2 1.1 0.3 0.3 1.1 0.3 0.2 PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 199.0;Endothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.8" "Group enriched" "Detected in many" 9 "granulocytes: 5.8;monocytes: 2.4;T-cells: 2.3" "Cell line enhanced" "Detected in all" "RT4: 76.1" "Low region specificity" "Detected in all" "HPA005751, HPA071988" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Nucleoplasm "HPA005751: AB_1855350, HPA071988: AB_2686479" "unprognostic (1.98e-1)" "unprognostic (3.75e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.32e-2)" "prognostic favorable (3.62e-4)" "unprognostic (4.88e-2)" "unprognostic (3.33e-3)" "unprognostic (4.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.99e-3)" "unprognostic (2.87e-2)" "unprognostic (9.74e-2)" "unprognostic (6.71e-2)" "unprognostic (8.22e-3)" 31.2 12.2 13.0 7.2 11.2 0.7 28.0 35.9 14.8 15.3 14.0 7.5 3.2 15.9 10.3 7.1 10.1 10.7 35.2 11.4 14.9 16.2 4.0 18.5 6.2 16.7 17.3 4.1 4.7 12.1 8.5 13.3 16.8 12.0 4.9 17.9 12.5 6.1 12.0 6.4 8.6 11.5 15.5 11.2 9.9 25.4 15.9 10.8 14.2 18.5 5.3 14.8 7.4 11.4 10.9 3.6 47.4 24.4 4.6 2.0 15.2 6.3 4.6 8.2 10.1 2.1 3.2 14.3 18.9 2.5 9.9 6.4 16.9 5.8 5.3 11.1 15.0 9.3 41.8 1.6 1.5 8.3 11.8 5.8 3.3 8.7 3.2 7.8 17.3 32.8 3.5 10.0 11.8 16.7 33.4 5.1 16.9 3.1 9.6 42.0 12.7 17.0 20.4 76.1 34.4 24.9 20.5 53.5 5.7 28.5 14.9 7.3 32.4 8.7 8.0 1.5 6.2 14.1 15.8 8.5 6.9 10.9 4.5 0.0 0.2 5.8 2.0 0.3 1.9 0.3 0.4 1.8 0.0 0.0 0.1 1.1 0.0 0.0 2.4 0.3 2.3 0.6 13.0 11.2 35.9 14.8 11.4 14.9 16.7 17.3 16.8 15.5 15.9 11.4 199.0 0.0 8.4 15.7 3.1 2.5 5.4 42.1 14.8 48.3 32.0 30.1 21.1 0.0 28.8 18.4 45.9 4.4 13.9 21.7 0.0 0.6 11.8 13.9 21.0 83.3 7.8 5.9 26.2 1.2 1.1 16.2 55.5 26.2 9.5 6.1 0.0 0.0 1.7 3.3 55.9 8.6 38.7 0.0 4.4 19.9 1.2 8.4 5.4 60.9 0.9 33.5 3.1 22.1 7.1 1.4 1.5 7.9 10.1 7.2 4.5 4.2 26.7 42.8 0.0 13.3 18.0 35.9 31.7 8.0 1.8 1.4 15.7 19.2 6.6 5.0 PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697261 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1255.9;Inhibitory neurons: 330.9;Oligodendrocyte precursor cells: 281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" 25.7 8.9 27.2 5.6 30.1 3.8 18.6 23.5 26.9 8.7 13.2 7.6 1.5 7.8 3.8 9.8 10.9 3.8 13.3 22.7 31.2 21.8 9.8 15.1 8.8 38.4 41.0 15.2 23.1 1.8 13.7 6.0 28.2 11.9 2.2 15.0 14.1 4.4 5.4 4.9 8.7 3.5 28.7 9.4 12.6 2.5 42.7 8.4 9.0 5.0 7.4 12.0 9.2 20.1 4.2 1.0 4.5 6.8 2.8 5.1 3.9 6.0 2.9 0.8 0.4 0.0 6.4 4.6 1.4 3.6 1.7 2.0 6.7 6.0 1.1 9.3 3.0 0.7 7.6 3.4 0.7 1.4 9.8 3.6 2.2 0.9 2.5 0.5 3.2 6.5 0.3 16.9 2.3 7.0 10.9 2.8 6.6 1.8 7.7 15.2 0.9 4.2 9.7 5.4 4.7 13.0 1.7 3.3 4.1 4.8 3.0 4.7 3.7 1.8 1.0 2.4 2.9 13.2 6.2 3.7 14.4 4.6 1.6 0.7 1.4 10.3 11.1 2.6 5.7 0.5 6.9 9.2 0.9 1.3 8.2 8.3 1.7 5.2 4.1 0.1 2.8 4.1 27.2 30.1 23.5 26.9 22.7 31.2 38.4 41.0 28.2 28.7 42.7 20.1 102.6 9.6 1.1 1255.9 9.6 5.4 55.6 4.6 8.0 15.2 7.7 4.1 6.9 21.5 4.6 0.0 2.1 7.9 84.0 5.8 21.5 43.3 0.2 13.7 5.7 59.8 6.0 4.0 88.4 49.1 13.6 18.9 8.2 30.9 5.1 7.7 21.4 10.1 13.8 74.0 330.9 1.3 4.1 21.4 22.3 1.4 5.0 17.7 10.6 103.0 20.2 34.6 84.5 281.5 9.7 38.7 4.4 14.7 28.0 32.9 0.1 21.2 3.4 21.8 26.3 66.5 25.7 0.4 3.8 9.0 4.3 3.4 75.7 2.7 3.8 54.3 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PPP1R9B "PPP1R6, PPP1R9, SPINO, Spn" ENSG00000108819 "Protein phosphatase 1 regulatory subunit 9B" Q96SB3 17 50133737-50150677 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 96.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022461 Approved NA NA 420000000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "CAB022461: " "unprognostic (4.71e-1)" "unprognostic (3.77e-2)" "unprognostic (3.82e-2)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.74e-3)" "unprognostic (1.99e-1)" "unprognostic (4.09e-2)" "unprognostic (2.80e-1)" "prognostic favorable (3.11e-4)" "unprognostic (8.50e-2)" "unprognostic (1.57e-2)" "unprognostic (1.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "unprognostic (4.29e-1)" 23.5 30.0 61.4 28.6 58.6 33.7 20.2 39.3 96.7 25.4 4.6 17.6 14.9 22.0 8.4 28.9 19.6 15.5 24.3 90.2 30.3 23.3 11.9 39.9 36.8 25.7 40.1 27.8 18.3 15.2 20.6 14.6 24.0 21.5 8.9 7.9 17.6 10.6 11.8 24.2 30.2 11.8 22.2 52.4 17.8 24.0 47.7 22.5 22.0 14.8 28.0 20.4 22.6 48.9 25.9 45.2 24.0 60.5 31.2 19.8 56.9 36.4 33.1 31.5 22.9 38.3 19.9 48.6 57.8 42.2 30.7 25.2 24.9 25.8 19.6 125.7 37.2 79.9 35.4 26.2 30.3 35.1 121.2 22.2 44.4 34.6 21.7 60.5 31.2 15.4 43.0 35.7 21.0 47.7 13.0 50.2 9.4 33.0 40.9 26.5 32.5 34.6 21.6 15.0 15.1 44.5 23.0 35.6 29.5 19.3 47.7 68.8 25.5 66.4 48.7 46.0 48.8 65.4 16.2 35.2 30.5 34.8 32.4 4.2 1.8 2.9 1.3 1.6 1.1 1.6 1.0 0.9 1.4 2.0 0.4 0.9 4.1 2.2 2.0 2.0 0.5 0.8 61.4 58.6 39.3 96.7 90.2 30.3 25.7 40.1 24.0 22.2 47.7 48.9 18.1 0.0 2.2 6.2 23.6 23.6 3.6 5.8 13.6 18.8 7.8 5.3 7.7 4.3 3.2 16.5 2.1 2.3 29.0 10.9 5.9 9.7 2.6 4.0 9.5 20.9 12.0 20.2 6.6 9.1 3.5 10.5 5.6 6.3 2.5 9.6 18.2 8.7 27.7 16.8 6.5 10.8 10.2 48.6 34.6 5.1 20.2 30.2 12.4 2.8 42.1 3.2 34.0 2.5 2.7 9.1 10.2 15.4 15.4 7.8 18.1 9.8 3.4 2.6 13.1 7.0 9.1 5.5 5.7 16.9 22.4 1.0 14.9 10.0 10.7 5.4 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 29.0 11.5 7.2 23.6 7.3 29.4 29.3 5.4 7.7 26.6 12.5 20.3 17.1 21.8 4.7 27.5 24.1 11.2 13.8 6.1 6.0 19.2 13.8 34.3 31.1 10.0 6.3 21.8 19.1 8.3 24.0 11.1 6.8 23.9 7.1 4.4 24.7 10.0 8.0 46.8 29.9 6.0 6.0 54.3 20.3 6.6 7.7 25.6 28.9 4.8 21.2 19.5 26.9 6.6 19.6 34.5 12.8 16.6 7.3 6.4 15.1 11.5 13.2 19.6 19.7 19.7 21.0 22.3 16.3 13.2 13.2 27.5 9.5 26.0 5.9 19.8 17.5 25.9 11.5 10.2 12.8 21.2 34.7 11.0 15.8 12.7 9.8 12.8 30.1 21.5 14.6 35.4 7.0 23.8 32.7 53.1 9.7 27.4 17.4 25.8 5.8 37.5 11.4 32.7 7.7 22.4 18.8 18.8 4.6 10.6 11.6 7.5 17.6 8.7 18.8 7.1 10.0 31.8 149.1 13.5 8.5 17.7 11.0 0.6 0.7 2.6 3.9 0.7 3.3 4.3 3.9 4.3 0.3 4.1 3.3 3.3 5.3 2.2 0.5 0.0 2.9 1.5 7.2 7.3 5.4 7.7 6.1 6.0 10.0 6.3 6.8 6.0 7.7 6.6 37.8 9.6 9.9 5.9 46.5 22.0 32.0 13.2 22.8 6.4 13.9 11.3 17.2 12.8 13.0 9.2 0.0 13.8 17.5 43.6 7.9 18.6 1.2 15.3 6.7 37.2 21.6 4.0 6.5 28.2 13.8 9.6 23.4 15.0 14.5 14.1 37.1 8.5 9.0 1.7 2.8 21.7 4.1 12.3 11.4 3.1 11.8 8.3 12.4 11.2 9.3 6.5 42.2 4.0 3.1 29.5 35.1 6.8 47.0 22.9 34.1 9.3 15.6 4.4 13.1 6.1 7.6 2.9 17.9 21.2 26.7 29.7 31.9 6.6 15.3 30.2 PRKX PKX1 ENSG00000183943 "Protein kinase X-linked" P51817 X 3604340-3713649 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 33.8" "Cell type enhanced" "Detected in many" "dendritic cells: 108.3;Endometrial ciliated cells: 164.0;Glandular and luminal cells: 179.5;NK-cells: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015324 Supported Supported Nucleoplasm No No "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA015324: AB_1855715" "unprognostic (1.07e-1)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.63e-1)" "unprognostic (2.45e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (4.14e-1)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (2.92e-1)" "unprognostic (1.07e-3)" "unprognostic (2.15e-2)" "unprognostic (9.91e-2)" "unprognostic (2.52e-1)" "unprognostic (1.70e-2)" 5.5 1.6 10.0 9.8 12.9 7.7 7.9 12.6 8.8 7.8 12.7 6.5 5.1 4.6 9.6 13.9 19.4 4.4 3.7 8.3 14.3 15.6 1.8 9.0 12.8 18.1 13.8 4.0 4.4 3.1 2.0 5.3 15.8 3.8 6.1 1.7 6.1 5.9 2.2 12.0 6.3 3.7 14.5 12.4 4.0 6.8 15.3 15.4 33.8 3.2 9.9 4.5 12.4 17.1 9.1 8.3 22.4 16.7 4.2 5.6 20.5 5.3 2.1 2.6 3.5 12.4 6.1 0.7 5.3 4.3 5.4 6.2 21.1 16.1 4.5 10.2 14.7 10.0 6.7 0.2 4.4 13.0 74.7 3.8 16.8 2.8 10.3 7.1 25.7 12.3 11.8 12.7 8.6 8.0 15.0 11.7 15.0 7.0 9.4 27.7 21.5 17.2 20.6 7.6 14.9 9.6 5.6 3.6 5.5 35.1 2.8 10.3 14.2 2.2 3.8 3.7 3.6 0.3 0.7 11.6 1.3 11.6 5.8 11.0 2.0 1.2 2.3 2.4 2.4 1.6 2.4 2.2 1.6 1.5 1.9 2.1 0.5 2.4 3.2 1.9 1.8 1.2 10.0 12.9 12.6 8.8 8.3 14.3 18.1 13.8 15.8 14.5 15.3 17.1 32.0 3.2 9.4 7.8 35.5 21.4 22.3 9.7 21.6 1.8 14.4 9.1 1.6 30.0 10.1 5.5 0.0 30.8 108.3 8.8 13.7 10.8 11.9 164.0 23.8 19.7 4.8 7.2 1.3 3.1 5.8 10.4 6.1 179.5 85.1 11.8 13.2 2.3 16.9 1.7 20.2 13.5 24.4 19.4 24.1 49.2 19.9 29.0 5.4 39.4 53.4 2.2 139.0 11.1 7.0 5.6 13.1 21.8 38.2 29.0 10.7 6.1 18.0 0.6 32.9 46.4 12.4 1.3 21.6 34.1 26.9 7.8 63.5 10.6 23.6 20.4 PRR29 "C17orf72, DKFZp761M2312, FLJ11724" ENSG00000224383 "Proline rich 29" P0C7W0 17 63998351-64004305 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 58.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 57.4;Respiratory ciliated cells: 89.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5;REH: 3.7;TIME: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051264 Uncertain Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA051264: " "unprognostic (2.05e-2)" "unprognostic (6.46e-2)" "unprognostic (2.87e-2)" "unprognostic (2.92e-3)" "unprognostic (4.71e-3)" "unprognostic (3.22e-2)" "unprognostic (3.84e-1)" "unprognostic (3.95e-2)" "unprognostic (1.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.63e-3)" "unprognostic (5.76e-2)" "unprognostic (1.30e-3)" "unprognostic (6.48e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (9.98e-3)" 2.0 0.3 3.2 0.5 2.5 0.3 2.2 1.8 1.2 6.1 12.7 0.4 0.2 0.6 0.3 0.2 58.2 0.7 1.5 4.1 4.2 1.9 0.2 10.4 0.4 12.7 16.0 0.6 0.3 0.9 10.7 0.3 7.3 0.7 0.0 0.0 0.5 0.6 0.6 0.4 0.7 0.2 9.0 5.7 0.3 13.9 4.0 0.2 4.7 0.0 0.3 0.8 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.2 0.0 3.5 0.0 0.3 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.0 0.5 0.0 0.0 0.0 1.3 0.0 0.1 0.7 0.1 3.7 0.0 1.5 0.3 0.0 0.2 1.0 0.0 0.1 0.2 0.5 0.5 0.0 2.8 0.1 1.1 0.4 0.1 0.4 0.1 0.2 0.4 0.1 0.0 0.9 0.2 0.0 0.4 0.5 0.1 0.1 0.4 0.2 0.1 0.2 0.7 0.4 0.2 0.2 0.4 0.0 0.2 0.3 3.2 2.5 1.8 1.2 4.1 4.2 12.7 16.0 7.3 9.0 4.0 3.9 3.3 0.0 2.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.2 1.5 9.9 3.7 0.0 0.0 0.7 0.0 0.0 0.1 12.4 57.4 0.5 2.1 0.0 0.0 0.5 0.0 0.1 0.6 0.0 1.1 0.0 1.6 1.8 0.5 0.3 0.0 0.4 0.0 0.0 0.0 0.0 10.5 0.0 0.9 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 2.0 0.0 0.0 0.1 89.6 0.0 0.0 0.3 0.3 18.1 1.4 0.0 0.0 0.3 0.7 3.5 0.0 0.1 PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" 8.6 3.7 12.3 2.1 24.9 0.2 5.2 21.6 19.7 4.4 4.7 4.0 2.9 4.3 1.5 4.1 2.6 8.8 6.4 12.9 15.9 10.5 7.9 5.5 1.7 26.7 21.3 4.2 1.6 1.2 1.4 8.1 25.3 3.4 4.1 1.5 2.9 7.8 15.9 2.2 3.0 5.4 18.4 2.9 2.4 1.5 18.4 1.5 8.3 7.8 1.0 5.6 3.8 39.4 32.3 7.2 5.6 5.6 18.7 15.4 2.4 14.1 17.6 4.7 8.2 17.1 20.2 0.0 21.8 10.4 8.9 10.7 15.6 10.0 8.3 0.1 5.2 5.2 7.7 5.7 22.6 0.0 7.2 23.2 8.1 9.1 7.7 9.4 24.8 0.0 2.6 0.1 16.5 2.4 0.1 0.1 6.8 5.1 13.4 0.0 13.1 0.0 79.2 1.7 0.0 0.1 9.7 15.6 6.1 15.3 0.1 3.5 17.6 7.5 4.2 14.2 4.1 0.0 0.1 0.0 7.3 0.0 7.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.3 24.9 21.6 19.7 12.9 15.9 26.7 21.3 25.3 18.4 18.4 39.4 29.7 6.4 4.2 15.7 0.0 11.3 4.8 7.6 5.2 2.2 5.3 5.3 8.1 15.7 2.7 33.1 0.0 7.0 0.2 7.6 7.9 6.8 0.7 3.3 12.9 18.4 3.0 0.0 23.3 3.1 14.9 9.6 4.6 9.2 1.3 3.9 17.9 16.3 4.8 18.5 10.8 5.7 14.2 4.1 5.3 0.4 4.7 1.4 3.6 31.9 0.8 2.2 0.0 12.5 229.8 18.7 7.5 2.6 0.0 9.1 4.3 9.4 2.9 0.5 6.6 8.3 8.4 2.5 4.2 5.2 6.3 10.4 0.4 3.5 4.8 8.1 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.6;Astrocytes: 143.0;Collecting duct cells: 69.9;Endothelial cells: 53.0;Oligodendrocytes: 45.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 26.9;HUVEC TERT2: 12.1;NB-4: 14.3;RPTEC TERT1: 13.3;TIME: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 44.6 2.8 29.2 2.6 35.0 1.4 44.0 30.3 29.2 26.0 12.5 9.9 4.0 16.4 6.9 13.2 24.1 13.2 21.1 31.4 21.3 40.0 1.9 11.9 4.4 33.6 29.6 38.2 4.7 5.8 6.4 8.9 28.0 13.5 2.4 0.9 21.2 11.0 11.4 9.8 8.8 5.1 22.4 16.2 11.5 3.5 28.9 1.6 32.4 9.0 2.1 14.9 21.3 39.7 2.3 0.6 0.7 2.4 0.3 2.3 0.9 1.7 1.5 0.7 0.4 0.3 6.1 0.1 26.9 3.0 1.1 2.4 0.8 4.5 0.3 3.0 0.4 0.2 2.6 0.2 0.2 0.4 0.3 0.9 0.3 1.3 0.8 3.4 12.1 0.6 0.1 2.9 0.5 1.5 0.0 14.3 0.6 1.0 3.7 0.4 0.1 1.0 13.3 2.5 0.2 0.3 0.2 1.7 0.4 0.8 6.7 0.6 12.0 6.6 1.1 1.5 0.6 1.0 0.4 0.2 4.1 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 35.0 30.3 29.2 31.4 21.3 33.6 29.6 28.0 22.4 28.9 39.7 130.6 0.0 11.7 143.0 0.7 2.7 5.8 2.6 13.1 0.5 4.5 4.8 15.7 2.8 3.6 69.9 0.0 0.2 1.4 1.7 7.9 1.1 1.6 11.8 2.4 53.0 0.0 0.0 1.5 0.7 0.4 6.3 18.3 21.2 3.8 1.5 20.7 0.2 0.9 0.0 2.9 6.6 4.1 0.6 2.6 3.7 24.2 1.5 5.4 12.2 0.0 1.5 2.1 10.6 45.7 5.8 6.3 8.6 4.4 11.6 0.8 41.3 1.9 0.5 6.6 2.7 5.1 1.2 1.6 1.4 3.3 0.3 1.3 6.6 0.8 17.2 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RBP5 CRBPIII ENSG00000139194 "Retinol binding protein 5" P82980 12 7115736-7128889 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 443.5;liver: 324.2" "Cell type enriched" "Detected in many" 8 "Proximal tubular cells: 3197.2" "Group enriched" "Detected in all" 8 "liver cancer: 70.1;renal cancer: 126.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.0;Hep G2: 13.4;K-562: 26.3" HPA038723 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Vesicles "HPA038723: AB_2676175" "unprognostic (5.70e-3)" "unprognostic (7.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.87e-2)" "unprognostic (1.39e-3)" "unprognostic (2.49e-2)" "prognostic favorable (8.37e-4)" "unprognostic (1.04e-1)" "unprognostic (2.65e-1)" "unprognostic (1.13e-2)" "unprognostic (1.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-2)" "unprognostic (3.33e-2)" "unprognostic (4.22e-1)" "prognostic favorable (3.68e-4)" 6.4 11.7 0.0 15.0 0.1 1.6 5.1 0.3 0.3 11.2 0.2 8.5 4.6 8.6 3.2 3.8 8.1 5.9 1.4 0.0 0.0 443.5 324.2 3.8 31.2 0.5 0.3 4.9 5.2 1.3 6.2 0.3 0.3 10.0 4.9 0.8 3.7 5.0 0.7 2.4 20.6 5.4 0.0 97.1 5.2 2.2 0.2 14.2 7.9 0.0 21.4 7.4 4.6 0.0 0.9 1.3 0.0 0.3 0.0 0.0 0.2 1.1 0.0 0.0 0.2 1.1 1.2 1.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 1.6 0.0 6.0 3.9 13.4 0.0 0.2 0.9 0.2 0.0 0.0 0.0 2.4 0.0 0.6 26.3 0.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.2 1.4 0.9 0.0 0.6 0.5 0.7 0.7 0.6 0.5 2.8 0.4 0.3 0.1 0.0 0.3 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.5 0.3 0.3 0.0 0.2 0.0 4.9 0.0 0.6 0.7 15.2 1.5 0.5 0.1 0.0 1.2 1.3 1.3 0.1 5.7 0.1 80.9 0.0 0.1 0.3 0.1 352.1 0.2 4.1 0.3 1.7 28.8 0.0 0.0 2.1 0.4 0.0 8.2 0.0 0.5 0.0 0.2 8.9 361.1 0.1 5.0 1.1 0.0 0.0 8.1 2.6 6.7 2.5 16.6 0.0 1.9 0.0 1.4 0.0 0.5 0.1 0.2 0.0 0.4 0.1 0.5 0.0 3197.2 0.9 1.7 0.0 0.1 4.3 0.7 0.4 0.2 2.3 0.0 7.3 2.4 0.1 0.3 RBP7 CRBPIV ENSG00000162444 "Retinol binding protein 7" Q96R05 1 9997206-10016021 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 401.0;breast: 394.6" "Cell type enriched" "Detected in many" 7 "Adipocytes: 3631.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 311.5;neutrophil: 344.7" "Group enriched" "Detected in many" 31 "granulocytes: 344.7;monocytes: 311.5" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;SK-MEL-30: 9.8;T-47d: 34.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA034749 Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Cytosol" "HPA034749: AB_10602084" "unprognostic (1.93e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (9.59e-2)" "unprognostic (2.31e-1)" "unprognostic (6.28e-2)" "unprognostic (1.39e-2)" "unprognostic (1.85e-1)" "unprognostic (1.05e-3)" "unprognostic (2.24e-1)" "unprognostic (1.46e-2)" "unprognostic (7.90e-2)" "unprognostic (5.07e-2)" "unprognostic (2.38e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.61e-2)" 401.0 15.0 20.7 8.9 27.0 28.6 394.6 23.8 38.3 22.6 23.4 15.0 2.6 20.4 4.2 34.4 14.7 51.6 86.6 20.4 22.4 72.9 9.6 8.8 8.3 23.7 24.0 12.7 11.9 68.9 16.7 15.9 23.7 18.6 4.4 5.0 22.3 8.1 16.0 35.4 11.5 14.9 23.5 112.1 17.2 9.2 22.4 12.6 36.2 24.9 5.6 23.6 27.9 36.4 0.0 0.6 0.3 0.0 0.0 0.5 0.0 0.0 0.0 2.5 0.9 2.5 3.2 0.0 13.0 1.3 0.0 0.0 0.1 1.0 4.4 0.0 2.8 0.0 0.1 1.3 1.6 0.0 0.0 0.0 2.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 3.4 0.0 0.0 0.0 0.7 0.0 0.2 0.5 2.6 0.2 9.8 3.5 34.8 2.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 311.5 2.8 0.4 138.4 0.2 0.1 0.0 0.1 10.6 0.2 0.2 0.1 344.7 0.0 68.3 2.0 0.7 96.8 20.7 27.0 23.8 38.3 20.4 22.4 23.7 24.0 23.7 23.5 22.4 36.4 3631.8 0.0 1.3 0.7 9.5 20.6 9.5 2.6 9.1 0.2 43.0 73.9 22.9 10.0 1.2 1.8 0.0 5.0 16.2 0.1 23.5 2.0 3.2 2.5 15.8 349.2 0.0 5.7 0.4 2.8 1.9 36.1 0.0 4.8 3.8 7.1 69.7 3.7 63.7 0.0 0.4 0.4 2.0 502.5 14.1 6.1 6.2 42.5 21.4 1.0 149.7 2.1 3.1 0.0 13.4 2.7 0.1 0.7 2.7 20.7 0.0 1.4 0.9 1.5 0.0 3.9 20.5 1.8 2.8 26.2 17.6 6.2 3.8 3.6 0.6 6.3 RFTN1 "FLJ23866, KIAA0084, MIG2, Raftlin" ENSG00000131378 "Raftlin, lipid raft linker 1" Q14699 3 16313574-16514026 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 87.6;monocytes: 143.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 151.7;Daudi: 122.9;HDLM-2: 177.5;SH-SY5Y: 132.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048725 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "HPA048725: AB_2680502" "unprognostic (1.98e-1)" "unprognostic (5.82e-2)" "unprognostic (1.44e-1)" "unprognostic (1.61e-1)" "unprognostic (5.92e-2)" "unprognostic (1.19e-2)" "unprognostic (1.87e-1)" "unprognostic (7.55e-3)" "unprognostic (9.99e-3)" "unprognostic (7.24e-2)" "unprognostic (2.75e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.29e-7)" "unprognostic (6.19e-2)" "unprognostic (1.49e-2)" "unprognostic (2.88e-2)" "unprognostic (2.81e-1)" 57.2 11.2 15.1 44.7 18.3 13.3 33.2 13.6 22.7 28.2 15.8 15.2 9.3 36.6 4.9 14.5 26.0 15.4 44.7 18.3 20.2 18.4 24.8 46.9 117.0 21.7 14.9 30.4 4.7 9.0 7.4 51.0 16.1 16.4 14.1 11.4 11.3 10.3 25.5 17.1 22.8 31.3 13.9 45.5 11.8 7.0 15.2 73.2 53.4 26.6 117.4 26.2 14.5 17.5 0.1 2.9 5.3 0.0 151.7 75.7 7.7 38.8 65.9 19.3 15.6 21.5 1.0 122.9 18.6 71.2 4.3 0.6 0.1 51.4 25.5 177.5 9.0 19.8 4.9 0.3 78.6 14.7 10.8 111.3 3.4 60.7 19.0 67.5 40.5 19.8 0.5 0.4 47.0 6.6 31.3 5.0 3.5 0.0 1.4 29.6 60.8 15.0 8.0 0.1 0.1 132.6 1.3 1.3 7.2 7.4 0.2 12.2 59.9 47.3 23.0 47.8 16.8 0.4 0.5 82.5 22.0 38.6 19.2 56.0 19.6 13.2 35.3 46.4 18.1 16.3 27.2 37.6 33.6 32.0 18.4 27.8 1.2 80.1 81.7 25.8 60.4 38.3 15.1 18.3 13.6 22.7 18.3 20.2 21.7 14.9 16.1 13.9 15.2 17.5 37.9 22.4 40.0 8.1 51.2 6.5 0.3 2.3 0.0 3.2 0.7 1.5 14.3 5.7 6.9 0.0 0.0 6.2 61.1 0.1 0.0 7.2 38.0 2.6 51.8 34.4 1.2 10.3 87.6 0.9 1.1 32.4 3.1 2.0 24.7 2.1 36.0 7.2 10.5 0.0 16.5 0.0 0.0 17.6 63.6 12.2 18.6 27.0 10.6 19.7 143.8 37.2 64.9 3.0 2.4 0.9 0.1 8.6 43.2 0.6 0.0 0.4 3.3 3.2 0.0 28.2 35.2 2.8 2.4 0.8 5.1 2.5 39.5 12.6 0.3 0.4 RIPOR3 "C20orf175, C20orf176, dJ530I15.2, dJ530I15.3, FAM65C" ENSG00000042062 "RIPOR family member 3" Q96MK2 20 50586108-50691542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Collecting duct cells: 3.7;Endometrial stromal cells: 6.5;Fibroblasts: 3.8;monocytes: 2.0;Proximal tubular cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 16.7;HEL: 55.9;HSkMC: 33.0;K-562: 33.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA051823, HPA054759" Uncertain Approved Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051823: AB_2681626, HPA054759: AB_2682596" "unprognostic (7.23e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.38e-2)" "prognostic favorable (1.66e-5)" "unprognostic (4.96e-4)" "unprognostic (1.32e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-1)" "unprognostic (2.88e-2)" "unprognostic (1.13e-1)" "unprognostic (1.10e-3)" "unprognostic (1.98e-1)" "unprognostic (9.21e-3)" "unprognostic (1.67e-2)" "unprognostic (4.58e-2)" 19.4 13.3 2.7 3.4 3.0 22.4 11.7 2.7 3.5 38.5 5.1 8.5 2.5 18.2 1.0 5.3 27.7 3.2 16.6 2.7 2.6 28.9 14.1 5.3 4.7 3.0 2.9 8.3 3.0 0.8 9.1 1.9 2.9 6.0 1.5 0.1 6.9 0.6 7.8 5.5 11.3 4.4 2.6 7.5 5.8 6.1 2.8 4.7 7.5 3.8 1.3 8.2 16.6 2.6 0.0 0.0 0.9 0.0 36.0 16.7 0.1 0.0 11.6 0.0 0.2 0.3 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 55.9 0.0 0.2 4.3 0.0 0.0 33.0 0.0 1.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.9 0.0 3.2 0.0 0.0 5.3 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 2.7 3.0 2.7 3.5 2.7 2.6 3.0 2.9 2.9 2.6 2.8 2.6 1.1 3.2 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.6 3.7 0.0 0.6 0.4 0.0 0.0 0.5 0.0 0.8 6.5 0.2 0.0 0.0 0.0 0.4 0.4 3.8 0.0 1.6 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.9 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.0 SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane" "Golgi apparatus" "HPA047533: AB_2680078" "unprognostic (8.81e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "prognostic favorable (1.94e-5)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.99e-5)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-2)" "unprognostic (6.17e-2)" "unprognostic (6.24e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.95e-4)" "unprognostic (7.89e-2)" 142.9 138.1 66.2 83.4 69.4 172.2 136.2 69.0 80.4 147.1 76.6 110.8 82.9 111.0 202.5 81.6 103.6 97.5 98.4 63.7 72.6 137.2 152.3 107.9 112.6 74.1 67.2 168.6 139.4 114.6 84.5 115.1 73.9 82.0 124.9 37.0 95.9 87.5 154.3 70.5 86.4 96.3 72.4 86.2 95.3 61.5 69.4 93.2 177.5 147.4 98.2 137.3 94.0 75.3 201.7 320.7 286.7 425.4 368.5 462.8 225.4 310.1 356.5 241.9 291.2 347.1 443.0 99.0 198.8 370.3 277.2 408.3 409.1 243.4 255.5 267.1 239.4 279.4 358.8 324.9 311.7 213.4 281.2 315.8 305.0 169.1 285.1 366.0 337.9 116.7 295.8 244.3 315.1 363.1 89.2 345.8 282.1 266.2 135.4 101.6 368.4 302.9 472.6 424.4 131.2 300.8 257.3 239.5 598.5 407.0 248.5 416.6 254.3 240.0 181.0 209.8 361.9 224.4 509.6 150.0 226.4 331.7 180.6 83.5 161.1 89.7 95.1 173.7 95.0 101.0 114.8 104.7 165.8 90.0 95.1 98.0 111.6 134.3 184.8 160.9 168.8 200.8 66.2 69.4 69.0 80.4 63.7 72.6 74.1 67.2 73.9 72.4 69.4 75.3 261.1 89.8 99.1 25.8 131.8 107.1 179.4 356.6 90.5 30.0 163.7 202.6 68.2 228.8 188.0 128.8 22.9 309.1 171.9 111.1 238.7 258.8 46.3 118.5 268.0 217.2 157.4 101.7 21.2 247.3 655.3 206.0 120.8 184.1 218.4 191.0 197.7 165.5 363.3 20.2 22.8 218.7 168.9 386.7 337.2 100.6 299.5 337.3 158.3 24.4 396.7 110.5 204.9 26.7 38.3 183.4 136.3 166.3 197.9 185.7 142.7 350.9 99.3 38.2 170.9 173.5 225.5 233.5 169.6 135.2 119.9 305.8 153.4 237.6 210.7 242.2 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 80.1;breast: 64.2" "Cell type enriched" "Detected in many" 6 "Adipocytes: 151.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "ASC diff: 26.1;Hep G2: 7.1;HUVEC TERT2: 7.4;THP-1: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" NA NA 5600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA001761: AB_1079902" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "unprognostic (7.08e-2)" "unprognostic (1.47e-2)" "unprognostic (2.85e-1)" "unprognostic (5.79e-4)" "unprognostic (5.20e-3)" "unprognostic (9.14e-2)" "unprognostic (5.54e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-3)" "unprognostic (4.14e-1)" "prognostic favorable (8.86e-5)" "unprognostic (5.63e-2)" "unprognostic (2.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" 80.1 1.9 9.9 3.4 9.4 0.1 64.2 18.9 11.4 5.1 6.2 6.8 3.0 5.9 1.3 4.5 5.2 5.9 18.6 8.4 9.0 19.8 1.3 23.9 1.6 10.8 10.0 3.2 3.1 1.8 2.4 26.7 11.3 4.6 3.7 0.4 10.6 2.5 12.8 12.7 9.6 3.9 9.9 8.0 5.7 1.3 12.1 1.7 7.7 18.6 1.8 8.3 7.8 9.1 0.0 0.1 0.1 0.2 26.1 0.2 2.5 0.0 0.0 0.0 0.0 0.7 0.3 3.3 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 3.9 0.2 7.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 7.4 2.6 0.0 0.4 0.0 0.3 0.2 4.3 1.2 0.7 0.1 0.0 0.0 4.1 0.0 0.3 0.5 0.5 0.0 0.4 0.5 0.1 1.9 6.5 2.9 0.1 2.4 0.0 0.0 0.5 2.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 9.9 9.4 18.9 11.4 8.4 9.0 10.8 10.0 11.3 9.9 12.1 9.1 151.5 3.2 1.3 0.0 0.3 0.4 0.1 0.1 0.0 1.7 5.1 5.5 10.7 0.0 0.0 3.7 0.0 1.7 0.9 0.3 0.0 0.0 3.0 2.8 1.6 20.4 9.6 0.0 0.0 0.0 0.2 3.6 1.1 5.8 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.3 5.0 0.3 0.5 0.0 24.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.2 0.2 0.0 9.4 0.0 0.1 0.2 0.0 4.1 3.0 0.1 0.1 0.5 0.1 7.5 0.4 0.1 0.2 0.0 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 22.2 10.9 10.2 21.9 6.8 60.7 13.3 3.5 9.3 8.6 8.5 11.4 8.1 8.5 3.3 7.7 8.1 18.6 23.4 5.8 6.5 14.3 17.4 20.5 21.0 12.0 7.3 5.5 10.2 5.8 8.0 24.4 10.0 7.3 13.5 3.7 5.3 5.9 9.6 4.1 12.5 13.6 10.1 37.1 7.1 9.5 12.1 10.5 11.1 9.5 15.8 15.7 6.0 14.7 9.2 5.5 7.0 7.3 23.9 35.5 4.8 29.2 79.5 21.9 23.3 8.4 5.2 15.6 20.3 44.6 73.6 1.7 5.5 16.9 35.2 13.3 2.7 53.2 2.6 6.2 23.3 23.5 122.2 21.2 3.8 140.7 12.7 48.4 119.1 12.8 38.9 6.1 80.2 3.2 9.7 46.7 11.0 2.4 21.0 9.5 15.9 10.2 10.5 3.7 4.6 4.9 5.4 0.6 42.2 6.2 3.5 33.4 93.0 20.0 11.3 17.4 48.1 13.9 15.8 17.6 211.6 16.6 165.3 0.9 3.5 1.2 1.2 8.4 1.0 1.5 1.1 1.3 4.8 0.5 0.7 1.0 3.0 1.8 6.6 4.9 0.4 1.8 10.2 6.8 3.5 9.3 5.8 6.5 12.0 7.3 10.0 10.1 12.1 14.7 26.8 3.2 22.0 2.6 26.2 6.8 1.5 4.2 1.2 4.6 4.3 3.8 17.5 4.3 4.3 1.8 2.1 0.4 40.6 15.0 1.9 3.6 13.1 1.0 2.2 39.2 3.5 11.2 11.0 9.0 1.4 8.1 0.5 1.2 38.6 0.8 46.1 11.1 40.4 3.3 7.3 3.0 6.1 113.6 130.9 5.3 2.8 84.1 16.0 38.4 67.1 1.1 18.6 11.1 9.0 7.2 5.9 4.1 4.9 3.0 0.8 1.5 3.5 3.4 0.0 4.0 12.7 12.5 4.5 0.7 4.1 1.0 12.1 4.4 3.2 1.2 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SLC12A7 "DKFZP434F076, KCC4" ENSG00000113504 "Solute carrier family 12 member 7" Q9Y666 5 1050384-1112063 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 77.3" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041652 Approved Uncertain Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA041652: AB_10793971" "unprognostic (2.22e-2)" "unprognostic (1.56e-1)" "unprognostic (8.92e-2)" "unprognostic (2.86e-1)" "unprognostic (1.69e-2)" "unprognostic (8.72e-2)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.67e-1)" "unprognostic (1.71e-3)" "unprognostic (4.40e-2)" "unprognostic (4.50e-2)" "unprognostic (3.44e-2)" "unprognostic (1.65e-3)" "unprognostic (1.17e-3)" "unprognostic (1.26e-1)" "unprognostic (3.93e-2)" "prognostic favorable (3.16e-5)" 21.1 14.6 8.9 7.2 8.0 4.0 18.8 7.2 10.4 15.8 12.3 24.1 24.0 13.8 1.0 8.0 16.6 12.0 77.3 7.9 12.0 45.1 72.4 23.1 5.7 8.0 10.7 12.3 27.6 4.4 20.5 2.9 8.0 20.7 5.4 5.5 18.9 3.0 6.3 15.8 31.9 3.3 6.8 34.9 28.1 29.9 9.4 7.8 24.7 3.1 2.2 14.5 10.8 7.1 3.8 10.0 5.5 17.3 0.8 0.9 8.7 0.2 1.1 0.8 0.0 24.5 6.4 0.0 20.0 0.3 6.8 7.6 4.6 6.1 0.0 23.0 6.1 4.8 13.4 8.6 12.2 0.0 10.4 1.8 0.8 0.0 1.8 0.3 5.5 2.2 7.6 0.2 0.0 12.0 14.8 0.1 11.9 14.4 16.3 43.9 24.0 20.5 6.5 14.8 3.1 3.8 5.6 0.1 6.0 3.3 9.7 2.7 4.8 0.0 5.7 0.0 0.0 0.3 0.0 2.5 0.0 0.6 2.8 0.2 1.8 0.0 1.1 2.7 1.2 0.6 1.1 1.3 2.1 0.6 1.2 1.2 0.0 1.4 3.8 0.9 1.1 1.3 8.9 8.0 7.2 10.4 7.9 12.0 8.0 10.7 8.0 6.8 9.4 7.1 21.3 9.6 15.2 8.5 7.3 7.0 6.3 8.9 6.8 25.3 18.4 13.8 35.8 31.5 13.6 29.5 2.1 0.2 14.2 42.0 1.9 23.5 0.4 40.9 11.0 27.9 13.2 19.1 0.3 18.1 0.4 11.6 39.8 63.4 8.2 16.6 11.7 34.5 19.8 281.0 0.5 19.4 18.3 28.0 19.8 1.9 3.7 29.0 16.0 14.0 9.1 5.2 5.2 1.5 0.0 28.8 35.8 5.7 5.3 15.7 27.3 23.2 23.1 3.6 19.7 5.2 8.4 1.0 3.4 3.5 6.8 0.3 9.8 5.4 19.3 15.2 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC7A2 "ATRC2, CAT-2, HCAT2" ENSG00000003989 "Solute carrier family 7 member 2" P52569 8 17497088-17570573 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 176.7;parathyroid gland: 224.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 93.1;Glandular and luminal cells: 139.8;Hepatocytes: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 204.3;RT4: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009277 Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA009277: AB_2668229" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-2)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (7.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.76e-1)" "unprognostic (4.49e-1)" "unprognostic (1.34e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.65e-7)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.46e-2)" "unprognostic (8.98e-2)" "unprognostic (1.79e-1)" 28.6 11.6 7.9 3.4 7.0 0.2 17.2 9.5 9.6 32.5 16.6 6.2 2.4 15.2 17.8 11.3 42.5 11.2 12.2 10.0 8.0 8.0 176.7 7.5 2.7 14.1 6.2 84.4 83.1 224.1 7.1 9.8 12.6 14.2 4.3 17.6 5.1 7.2 114.5 8.1 4.5 13.4 12.7 3.8 8.3 15.4 7.1 3.1 45.1 45.8 3.5 10.5 14.9 15.9 0.0 3.1 1.0 32.4 0.2 0.3 35.1 0.3 22.1 1.7 2.0 10.7 0.1 0.0 7.4 0.0 4.7 0.0 23.5 5.4 7.4 0.0 12.3 0.0 24.8 23.2 204.3 10.3 0.0 27.7 4.5 27.2 25.7 0.0 10.2 0.0 0.2 0.0 24.9 35.5 1.3 11.7 11.8 7.4 2.9 0.0 16.2 17.6 2.7 55.3 0.4 4.3 1.7 0.8 9.9 23.5 0.0 1.2 22.9 0.0 11.8 0.1 0.1 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.0 9.5 9.6 10.0 8.0 14.1 6.2 12.6 12.7 7.1 15.9 9.4 12.8 78.1 58.8 0.4 8.3 6.6 5.8 20.5 2.9 52.0 25.8 15.5 38.6 16.3 7.3 35.5 22.6 0.1 0.4 0.0 8.3 12.8 67.0 40.4 5.6 87.9 10.7 0.5 93.1 15.1 20.6 0.5 139.8 2.5 0.4 7.1 249.0 5.8 0.0 19.9 3.6 0.0 6.7 2.3 22.9 37.9 1.4 3.6 1.9 0.6 23.5 0.0 11.6 2.6 20.5 0.6 27.8 0.1 50.2 0.3 3.7 53.9 38.0 59.2 8.8 75.7 0.3 1.1 7.8 3.8 26.0 1.6 9.5 3.2 8.4 SLCO2A1 "MATR1, OATP2A1, PGT, SLC21A2" ENSG00000174640 "Solute carrier organic anion transporter family member 2A1" Q92959 3 133932701-134052184 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 123.7" "Group enriched" "Detected in many" 4 "Distal enterocytes: 47.1;Endothelial cells: 65.2;Hepatic stellate cells: 146.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 90.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA013742 Enhanced NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013742: AB_2668877" "unprognostic (4.39e-3)" "unprognostic (2.84e-1)" "unprognostic (1.33e-1)" "prognostic favorable (9.69e-4)" "unprognostic (8.53e-2)" "unprognostic (2.32e-3)" "prognostic favorable (9.24e-5)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (7.60e-2)" "unprognostic (2.04e-2)" "unprognostic (6.87e-2)" "unprognostic (5.63e-3)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.78e-1)" "unprognostic (1.45e-1)" "unprognostic (3.07e-2)" 30.4 42.5 1.6 16.8 1.6 0.0 18.1 1.3 2.7 30.9 9.1 24.7 10.2 46.3 6.1 18.8 28.3 18.8 26.4 1.5 1.6 52.8 2.4 123.7 9.2 2.0 1.6 5.2 20.8 28.7 15.8 23.4 2.2 36.5 18.0 0.0 20.8 84.7 2.1 13.5 29.3 33.5 1.9 24.2 23.6 1.3 2.3 8.4 89.3 3.4 9.6 21.3 20.3 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 4.3 0.5 0.0 0.1 0.1 0.0 90.6 0.9 0.0 11.2 0.1 0.0 0.1 0.1 0.1 0.0 5.8 0.0 2.4 0.0 0.0 3.4 0.2 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.6 6.0 0.0 0.0 0.0 0.0 8.7 0.0 0.1 0.0 4.6 1.5 0.0 3.7 0.1 0.0 22.1 0.0 4.5 0.1 0.4 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 1.6 1.3 2.7 1.5 1.6 2.0 1.6 2.2 1.9 2.3 1.7 19.8 0.0 2.5 0.0 2.1 5.1 9.1 0.5 8.6 0.0 0.8 3.9 4.6 1.5 1.6 3.7 0.0 1.5 0.0 47.1 0.0 2.8 1.0 0.9 0.2 65.2 1.2 0.0 8.1 3.3 4.0 8.7 18.8 1.6 1.3 0.1 146.7 0.6 0.2 0.0 1.7 4.1 0.0 2.2 0.4 0.8 0.3 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.1 14.0 15.8 0.0 0.0 1.5 3.2 2.1 0.8 0.0 0.0 0.4 1.1 0.4 0.2 2.0 1.7 0.8 1.1 0.1 0.6 2.2 SLFN11 FLJ34922 ENSG00000172716 "Schlafen family member 11" Q7Z7L1 17 35350305-35373701 "Predicted intracellular proteins" "Antiviral defense, DNA damage, Immunity" "Helicase, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 70.6;dendritic cells: 39.9;Endothelial cells: 38.8;Langerhans cells: 53.0;Macrophages: 47.0;Smooth muscle cells: 38.8;T-cells: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 118.2" "Low region specificity" "Detected in many" "HPA023030, HPA062062" Uncertain Supported Nucleoplasm,Cytosol No NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA023030: AB_1856613, HPA062062: AB_2684673" "unprognostic (1.93e-2)" "unprognostic (2.56e-1)" "unprognostic (3.04e-2)" "unprognostic (1.03e-2)" "unprognostic (3.48e-3)" "unprognostic (1.01e-1)" "unprognostic (5.19e-2)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (9.93e-10)" "unprognostic (1.65e-1)" "unprognostic (5.71e-3)" "unprognostic (6.33e-2)" "unprognostic (8.81e-3)" 31.7 8.2 5.6 20.0 6.1 12.8 17.1 6.4 5.2 21.1 8.2 10.2 6.2 12.1 42.2 8.4 20.6 18.3 20.0 6.0 8.0 6.4 6.8 37.7 21.2 9.5 6.3 23.1 5.4 6.1 6.5 10.5 9.7 9.1 11.1 1.4 11.8 12.3 7.3 5.2 13.9 19.1 7.6 23.3 9.0 2.7 11.0 22.9 24.1 19.0 20.9 17.9 12.6 9.4 29.3 25.6 0.1 0.0 25.4 72.0 0.4 35.3 25.2 59.9 103.9 0.0 0.0 0.2 0.6 46.4 18.8 13.9 78.8 0.0 72.1 16.6 94.2 63.0 0.3 0.0 33.0 82.4 0.1 29.5 0.9 66.5 0.2 0.0 99.4 46.8 0.1 0.3 10.1 0.0 118.2 66.4 0.6 0.0 0.1 98.9 73.3 0.2 0.7 13.8 0.2 0.1 0.0 13.0 0.1 0.0 20.7 58.6 52.1 16.3 0.4 61.9 53.7 2.3 1.0 0.2 12.2 70.3 36.0 0.5 18.2 2.1 6.1 27.6 8.4 4.6 3.8 5.5 14.0 1.5 2.8 4.1 1.4 3.1 18.2 19.4 6.3 8.7 5.6 6.1 6.4 5.2 6.0 8.0 9.5 6.3 9.7 7.6 11.0 9.4 70.6 0.0 5.2 0.3 19.5 7.5 1.1 1.1 5.7 0.4 6.7 2.8 9.2 1.5 2.7 1.8 0.0 1.4 39.9 0.1 0.0 0.0 1.4 5.9 16.0 38.8 0.0 9.9 0.3 0.6 0.5 29.2 6.6 2.2 3.8 0.3 15.0 0.4 32.8 0.0 2.6 0.1 0.0 36.5 53.0 1.7 10.2 47.0 12.4 17.8 17.2 0.3 3.1 0.0 0.1 0.1 1.2 3.0 24.7 1.3 0.1 0.2 13.3 0.1 6.6 7.9 38.8 0.0 0.2 1.9 8.5 0.8 37.3 7.7 0.1 0.7 SNTG2 "G2SYN, SYN5" ENSG00000172554 "Syntrophin gamma 2" Q9NY99 2 950849-1367613 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 68.2;Excitatory neurons: 24.4;Horizontal cells: 90.9;Late spermatids: 44.7;Spermatocytes: 22.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HAP1: 1.7;JURKAT: 1.6;MOLT-4: 1.1;NTERA-2: 2.0;SCLC-21H: 2.0" "Low region specificity" "Detected in many" "HPA065258, HPA077904" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA065258: , HPA077904: " "unprognostic (7.52e-3)" "unprognostic (7.52e-4)" "unprognostic (4.15e-1)" "unprognostic (3.50e-2)" "unprognostic (2.52e-2)" "unprognostic (1.39e-3)" "unprognostic (2.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (7.87e-3)" "unprognostic (3.58e-3)" "unprognostic (3.64e-1)" "unprognostic (2.52e-1)" "unprognostic (1.77e-2)" "unprognostic (5.05e-2)" 2.0 0.3 0.6 0.0 0.7 0.0 1.8 1.0 0.6 1.0 1.1 0.5 0.1 1.2 0.2 0.5 1.2 0.2 0.4 1.7 0.7 0.1 0.0 0.3 0.0 1.7 0.9 0.2 0.9 0.0 2.9 0.0 1.3 0.6 0.2 2.1 0.5 0.0 0.4 1.1 0.6 0.7 0.4 3.2 0.3 1.8 0.7 0.2 0.7 0.9 0.1 0.8 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.0 0.6 1.7 0.7 1.7 0.9 1.3 0.4 0.7 0.6 6.8 0.0 0.0 0.7 0.4 0.9 0.1 0.0 0.6 0.8 0.2 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.2 0.1 0.9 7.3 0.0 0.0 24.4 0.2 0.5 0.8 0.0 0.0 0.0 3.0 0.0 0.0 0.1 90.9 10.7 0.0 0.0 0.0 1.2 44.7 0.3 0.0 1.8 9.4 0.0 0.6 0.0 1.5 1.3 0.0 0.0 4.1 0.0 0.3 0.0 0.5 0.0 4.6 0.0 0.3 0.4 22.0 5.4 0.1 0.1 0.0 0.2 0.2 0.0 0.2 SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.1" "Group enriched" "Detected in many" 8 "Adipocytes: 464.9;Endometrial ciliated cells: 377.3;Endothelial cells: 171.5;Glandular and luminal cells: 520.0" "Group enriched" "Detected in many" 4 "endometrial cancer: 122.8;ovarian cancer: 96.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "EFO-21: 108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB025594: , HPA068399: AB_2685981" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favorable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" 49.1 1.6 2.9 1.4 2.3 0.0 32.6 2.6 3.3 20.4 1.4 8.3 0.7 18.8 1.2 3.6 23.0 7.7 19.1 2.1 2.2 5.6 1.3 9.9 0.7 2.9 2.5 4.2 1.9 0.8 2.3 5.7 2.7 6.0 0.8 0.1 3.9 1.1 10.3 5.1 5.0 4.3 2.5 13.2 5.7 3.4 2.8 0.4 5.8 5.8 0.4 8.4 9.4 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 2.6 3.3 2.1 2.2 2.9 2.5 2.7 2.5 2.8 2.6 464.9 0.0 0.0 0.0 0.2 13.9 0.3 0.0 0.0 0.1 0.7 1.3 2.1 1.5 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 2.6 377.3 44.5 171.5 0.0 2.7 0.0 0.2 0.1 7.7 0.0 520.0 0.0 0.0 46.8 0.1 0.1 0.0 0.0 0.0 0.0 0.9 16.6 1.8 2.5 3.5 19.6 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 7.3 5.1 3.2 6.4 0.3 13.5 0.0 4.5 0.2 0.0 3.7 SP110 "IFI41, IFI75" ENSG00000135899 "SP110 nuclear body protein" Q9HB58 2 230165186-230225729 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.7" "Cell type enhanced" "Detected in many" "B-cells: 141.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 99.3" "Low region specificity" "Detected in all" HPA058554 Supported Nucleoplasm No No "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA058554: AB_2683754" "unprognostic (9.72e-2)" "unprognostic (1.15e-2)" "unprognostic (5.02e-2)" "unprognostic (8.33e-4)" "unprognostic (2.93e-1)" "unprognostic (1.80e-1)" "unprognostic (6.65e-2)" "unprognostic (9.44e-2)" "unprognostic (9.68e-2)" "unprognostic (1.46e-2)" "unprognostic (4.11e-3)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.38e-1)" "unprognostic (2.66e-2)" "unprognostic (2.99e-3)" "unprognostic (9.50e-3)" 14.0 7.3 8.4 38.5 10.3 29.8 11.8 9.4 10.8 11.6 11.5 12.6 11.9 10.5 7.9 9.2 9.6 18.0 8.1 8.1 10.3 11.9 14.8 21.0 53.7 15.3 10.9 16.5 7.9 9.7 5.3 17.5 11.6 9.6 14.0 2.0 17.0 7.6 5.7 7.8 17.6 13.4 12.1 49.8 12.9 3.1 10.9 35.7 7.4 8.4 50.1 18.9 9.3 12.3 8.3 4.4 2.7 4.7 14.2 23.6 8.3 14.8 30.8 70.3 99.3 0.2 12.7 34.5 13.8 15.8 67.0 5.1 9.0 23.0 25.7 30.5 6.0 14.9 6.2 8.9 14.5 22.1 17.1 32.7 11.8 20.8 27.4 13.2 25.3 23.6 5.3 12.1 20.6 4.9 33.0 43.5 8.6 4.2 5.1 20.1 25.4 12.8 56.2 11.1 0.5 5.7 5.7 12.7 32.7 0.9 9.6 18.5 18.8 12.9 7.9 3.2 7.5 12.9 4.6 16.2 14.4 20.6 10.7 92.2 49.7 124.4 55.2 85.8 47.8 142.8 53.5 50.5 44.1 135.8 54.1 58.7 268.6 56.9 143.4 84.4 70.7 48.5 8.4 10.3 9.4 10.8 8.1 10.3 15.3 10.9 11.6 12.1 10.9 12.3 77.8 44.8 23.8 17.3 141.7 9.9 5.2 25.7 16.5 0.4 21.6 19.3 3.7 7.2 19.6 11.0 0.0 3.8 84.0 17.0 13.7 19.9 5.2 17.2 21.3 28.6 6.7 9.7 1.1 28.5 12.7 22.8 9.2 20.1 38.0 21.2 26.4 6.2 26.9 0.0 2.1 11.4 73.2 47.4 25.8 4.2 11.8 62.3 19.6 42.2 56.7 9.7 59.8 19.6 18.2 26.0 11.6 10.1 35.7 3.5 10.7 14.4 21.0 4.9 6.6 8.6 16.2 4.8 2.3 9.8 10.1 4.7 68.8 23.5 6.1 3.0 SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;breast: 10.8" "Cell type enriched" "Detected in some" 7 "Adipocytes: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HUVEC TERT2: 34.0;TIME: 40.1" "Not detected" "Not detected" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" 12.4 1.2 2.9 0.6 2.5 0.0 10.8 2.2 3.3 0.7 1.1 1.2 0.3 1.2 0.1 0.5 1.2 0.6 8.9 2.3 2.2 4.2 0.8 3.2 0.4 3.0 2.6 0.7 0.5 0.5 0.6 4.7 3.1 1.0 0.4 1.4 0.7 0.5 3.1 0.9 0.9 0.6 2.3 0.7 0.9 7.5 3.3 0.2 1.9 1.8 0.0 1.5 0.8 2.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.1 0.2 0.0 0.0 34.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 40.1 0.0 0.8 2.7 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.5 2.2 3.3 2.3 2.2 3.0 2.6 3.1 2.3 3.3 2.4 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 105.4;Muller glia cells: 165.1;Pancreatic endocrine cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 127.6;TIME: 108.9;U-251 MG: 142.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "olfactory bulb: 5.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 18.9 4.1 4.0 10.5 3.0 17.3 18.0 2.1 3.9 11.0 2.3 7.0 1.9 6.7 3.9 23.8 9.4 11.9 17.5 2.9 3.9 21.4 3.8 24.3 8.1 4.0 4.1 4.3 14.4 4.8 4.9 2.5 4.5 7.3 1.1 8.4 19.9 1.5 3.2 15.6 7.0 3.2 2.3 5.0 6.7 5.8 8.5 3.5 10.6 0.8 4.1 11.3 13.1 3.9 36.9 3.7 15.2 0.8 7.6 7.0 15.8 82.6 54.0 67.8 40.8 19.4 3.9 1.8 7.4 61.0 28.9 7.7 11.7 105.4 16.4 1.6 6.2 0.5 28.3 127.6 16.6 1.3 2.9 13.6 2.1 105.9 41.3 28.8 66.0 3.7 17.3 0.2 13.5 46.6 3.5 0.6 0.9 8.2 29.7 2.5 4.1 2.8 3.7 0.5 2.0 3.6 8.3 0.9 74.4 9.1 3.0 5.1 108.9 105.8 20.8 82.3 142.1 1.7 0.4 1.6 80.5 6.5 16.1 1.5 1.9 0.0 0.7 0.9 0.2 0.0 0.1 0.2 0.5 0.1 0.0 0.1 0.2 0.0 0.2 4.8 0.0 0.8 4.0 3.0 2.1 3.9 2.9 3.9 4.0 4.1 4.5 2.3 8.5 3.9 22.0 0.0 0.0 1.0 2.8 12.6 57.0 18.6 2.8 1.5 31.1 29.1 5.3 47.1 6.6 1.8 0.0 1.2 9.1 1.0 0.0 105.4 0.2 15.3 13.5 51.2 0.0 22.3 0.5 12.7 16.9 27.5 3.1 60.7 7.0 0.4 4.2 0.2 30.1 33.7 1.6 2.4 6.1 8.9 45.4 1.4 3.7 39.9 12.4 1.0 61.5 165.1 3.1 0.0 0.1 101.8 1.2 19.9 3.5 68.9 0.8 2.5 2.0 3.9 0.0 17.3 54.3 0.0 9.5 6.7 10.7 1.4 4.2 0.8 0.4 27.0 STING1 "ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173" ENSG00000184584 "Stimulator of interferon response cGAMP interactor 1" Q86WV6 5 139475533-139482935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Host-virus interaction, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 25.3;Cardiomyocytes: 27.7;dendritic cells: 17.0;Hofbauer cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 64.4;EFO-21: 83.8;HDLM-2: 200.5;THP-1: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038116, HPA038534" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA038116: AB_2675841, HPA038534: AB_2676067" "unprognostic (1.45e-1)" "unprognostic (4.10e-3)" "unprognostic (1.29e-1)" "unprognostic (2.23e-2)" "unprognostic (2.70e-2)" "unprognostic (1.71e-2)" "unprognostic (7.66e-2)" "unprognostic (2.77e-2)" "unprognostic (6.30e-2)" "unprognostic (1.01e-1)" "unprognostic (5.69e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.59e-8)" "unprognostic (9.18e-3)" "unprognostic (4.14e-2)" "unprognostic (4.45e-2)" "unprognostic (1.34e-1)" 38.9 9.3 4.6 18.4 5.0 16.9 26.2 4.4 5.4 32.6 12.8 16.6 6.7 25.0 6.8 21.5 36.2 11.9 35.7 4.3 4.9 17.3 5.5 48.1 15.0 5.5 4.9 21.9 5.4 3.3 11.8 12.9 5.1 20.7 11.6 0.3 24.5 15.5 7.5 15.5 19.0 18.7 5.3 37.8 11.6 3.1 6.0 12.4 20.2 8.5 27.1 21.7 28.4 4.8 2.9 0.7 0.2 0.0 4.0 12.0 0.2 15.3 64.4 7.6 24.4 0.0 18.8 0.0 83.8 49.0 1.9 10.8 0.4 22.9 4.8 200.5 3.3 13.5 6.6 0.8 7.5 4.1 0.8 16.2 1.2 4.6 5.7 12.8 27.8 1.4 3.9 58.3 33.6 0.0 2.2 24.1 0.1 0.8 4.7 0.7 6.1 18.0 9.4 7.0 5.8 0.0 6.5 5.3 16.0 0.6 0.7 73.3 17.2 1.9 1.3 6.8 5.6 0.0 20.0 0.1 0.3 56.2 11.3 16.6 60.9 0.1 56.9 40.0 29.3 0.6 57.4 47.8 55.6 0.3 40.3 35.0 5.0 90.6 17.5 19.2 65.3 60.6 4.6 5.0 4.4 5.4 4.3 4.9 5.5 4.9 5.1 5.3 6.0 4.8 25.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.0 0.0 0.0 0.0 0.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.6 8.4 0.0 0.0 0.0 0.0 0.0 0.0 67.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.8 5.8 0.0 0.0 0.0 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042079-172188224 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5;lymphoid tissue: 45.2" "Cell type enhanced" "Detected in all" "dendritic cells: 107.7;Kupffer cells: 91.4;NK-cells: 171.0;T-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 143.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 16000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 14.9 5.7 3.1 37.1 3.6 76.5 11.4 18.4 5.6 4.5 3.5 8.5 8.4 4.9 1.7 5.6 4.7 13.2 7.6 3.1 4.0 5.9 6.2 18.4 44.1 6.2 4.4 2.5 7.2 3.1 4.1 17.2 5.8 4.4 6.9 1.2 4.7 3.5 5.0 14.2 16.0 7.8 5.4 45.2 11.1 14.0 6.4 20.6 5.3 5.5 25.0 14.9 5.2 7.0 22.2 20.2 12.7 18.8 14.7 18.1 31.5 28.4 24.0 20.2 18.9 10.6 28.6 26.8 14.6 35.6 42.3 25.4 5.7 35.1 13.5 35.0 9.3 32.1 8.2 6.1 20.2 32.7 36.4 17.4 7.5 27.4 23.1 7.5 18.3 10.4 3.0 36.2 14.7 35.7 23.5 73.4 5.0 11.3 16.1 38.2 9.9 17.7 8.2 27.6 8.3 10.2 16.4 22.5 77.9 15.6 8.2 68.7 24.8 22.3 11.3 15.8 15.5 30.2 48.4 17.1 29.4 49.8 143.3 16.7 26.5 23.4 36.5 46.3 26.9 10.0 19.3 26.3 22.5 8.1 11.0 20.0 48.9 16.9 71.8 7.1 26.7 44.0 3.1 3.6 18.4 5.6 3.1 4.0 6.2 4.4 5.8 5.4 6.4 7.0 35.8 3.2 11.2 1.6 40.5 6.6 8.4 7.2 5.7 4.3 3.3 3.7 3.8 5.7 6.1 1.8 6.2 4.1 107.7 11.8 1.9 4.5 2.5 3.5 4.6 23.9 12.0 11.8 8.5 6.2 27.2 9.3 20.9 7.1 28.4 3.6 18.2 2.3 36.3 47.1 7.9 19.9 2.0 91.4 43.8 3.2 2.8 61.3 8.8 32.8 49.8 2.1 171.0 10.1 14.4 10.7 11.8 1.5 42.8 11.7 6.5 2.0 6.1 2.2 13.1 5.1 10.2 5.3 7.8 2.6 4.1 5.1 81.4 11.4 5.3 10.7 STX11 ENSG00000135604 "Syntaxin 11" O75558 6 144150517-144191939 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 25.1;bone marrow: 56.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 85.0;granulocytes: 90.3;Langerhans cells: 271.6;Macrophages: 158.0;monocytes: 85.5;Suprabasal keratinocytes: 154.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 7 "basophil: 22.6;classical monocyte: 68.4;eosinophil: 43.5;intermediate monocyte: 81.1;myeloid DC: 25.4;neutrophil: 81.7;non-classical monocyte: 87.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.4;granulocytes: 81.7;monocytes: 87.0" "Cell line enhanced" "Detected in some" "HDLM-2: 17.2;Karpas-707: 10.1;RH-30: 6.9;TIME: 8.3;U-266/70: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007992 Approved NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007992: AB_1857620" "unprognostic (1.30e-3)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.62e-2)" "unprognostic (3.73e-2)" "unprognostic (8.96e-2)" "unprognostic (3.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-2)" "unprognostic (8.65e-2)" "unprognostic (1.36e-1)" "unprognostic (4.47e-3)" "unprognostic (7.07e-2)" "unprognostic (3.91e-2)" "unprognostic (8.50e-3)" "unprognostic (1.07e-1)" 25.1 4.4 0.6 5.8 0.6 56.5 14.5 0.6 1.1 1.9 0.7 2.8 1.0 1.4 0.3 5.1 2.6 2.1 7.3 0.7 0.8 3.6 3.1 21.3 5.5 1.0 0.7 0.9 1.1 0.6 2.1 2.4 0.9 1.3 0.9 0.2 2.1 0.3 2.5 8.2 3.3 1.9 0.8 14.1 2.0 1.1 0.9 1.8 7.5 0.9 3.5 4.0 3.2 1.1 0.4 0.1 0.1 3.9 0.2 0.3 0.6 0.4 0.3 0.4 0.7 0.1 0.4 0.1 0.4 0.6 0.7 0.6 0.0 0.1 0.2 17.2 0.6 3.0 0.6 0.1 1.0 0.9 0.5 0.0 0.0 0.2 0.1 0.2 4.3 0.8 0.1 10.1 0.5 0.2 0.4 0.9 0.0 0.0 0.3 0.1 6.9 0.6 0.0 1.9 0.2 0.1 1.2 0.1 1.7 0.3 0.1 3.8 8.3 0.2 1.0 0.4 0.3 11.6 4.6 0.1 0.2 2.1 0.4 22.6 68.4 43.5 6.0 81.1 3.8 1.4 2.7 5.1 25.4 2.4 1.0 3.0 81.7 3.2 87.0 2.7 8.3 43.9 0.6 0.6 0.6 1.1 0.7 0.8 1.0 0.7 0.9 0.8 0.9 1.1 41.9 54.5 10.7 0.0 16.6 85.0 11.3 6.3 3.4 0.0 11.1 4.6 4.5 4.3 6.6 1.8 0.0 0.9 38.1 0.1 0.0 6.4 0.4 3.7 0.7 23.7 3.5 6.1 0.1 2.6 5.7 11.2 0.5 5.0 90.3 0.2 8.2 1.4 30.1 0.0 0.1 0.4 2.0 73.7 271.6 1.2 0.6 158.0 44.4 2.8 85.5 0.0 21.6 0.0 0.1 6.1 3.3 0.0 63.1 14.4 0.0 0.1 10.7 0.1 0.0 46.6 9.7 3.0 3.8 11.2 154.6 28.0 36.6 3.2 0.6 33.3 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 TAF1C "MGC:39976, SL1, TAFI110, TAFI95" ENSG00000103168 "TATA-box binding protein associated factor, RNA polymerase I subunit C" Q15572 16 84177847-84187070 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072229 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli fibrillar center" "HPA072229: AB_2686499" "unprognostic (9.39e-2)" "unprognostic (1.13e-1)" "unprognostic (6.86e-3)" "unprognostic (8.20e-3)" "unprognostic (4.45e-2)" "unprognostic (3.47e-2)" "unprognostic (6.21e-2)" "unprognostic (1.26e-1)" "unprognostic (2.52e-1)" "unprognostic (3.53e-1)" "prognostic favorable (1.76e-4)" "unprognostic (1.06e-2)" "prognostic unfavorable (8.08e-6)" "unprognostic (5.60e-2)" "unprognostic (2.22e-1)" "unprognostic (1.82e-1)" "prognostic favorable (3.22e-4)" 19.4 15.8 9.8 7.2 9.9 13.5 20.6 8.1 12.9 25.9 5.4 16.0 7.9 23.5 2.2 15.9 21.4 10.1 18.3 10.9 7.7 20.6 14.8 17.0 11.1 10.5 8.7 31.7 17.9 4.2 20.6 6.2 8.6 21.7 2.9 1.8 15.3 8.3 12.3 17.8 19.3 5.3 7.3 32.2 18.7 13.8 8.9 7.4 23.7 6.7 3.6 18.5 19.1 8.9 11.8 12.7 7.5 23.6 5.7 5.9 34.3 13.8 5.3 11.5 3.7 15.0 8.3 12.7 17.3 5.0 6.1 21.2 4.3 5.4 2.6 11.4 18.2 6.8 21.0 9.7 4.8 7.6 21.8 8.9 6.9 9.1 3.7 5.0 20.4 20.7 17.9 4.1 5.6 25.4 11.3 24.9 27.8 5.1 12.2 29.2 6.1 10.5 4.7 9.5 34.0 16.8 26.3 7.8 43.0 4.6 28.9 8.1 8.9 19.2 16.5 19.2 12.0 19.6 16.9 26.7 9.8 9.2 12.4 0.0 1.3 0.4 1.5 1.3 1.8 0.9 0.6 0.9 1.5 1.1 0.7 1.3 0.0 1.5 0.5 0.6 0.9 1.2 9.8 9.9 8.1 12.9 10.9 7.7 10.5 8.7 8.6 7.3 8.9 8.9 24.9 19.2 15.8 22.5 9.2 6.5 5.1 5.2 5.2 9.3 10.2 10.2 3.0 2.8 8.2 3.7 20.9 9.4 6.5 9.9 5.9 5.1 0.5 6.9 7.4 18.7 7.2 7.4 16.5 7.1 6.7 8.4 20.9 8.8 6.3 24.6 22.9 12.9 6.6 1.7 13.0 8.2 0.0 9.8 6.3 2.5 11.8 7.3 7.2 15.9 6.3 7.8 5.2 13.6 12.5 5.2 5.1 9.1 12.1 3.9 7.6 4.0 6.1 10.4 6.6 8.3 7.8 9.9 10.6 8.7 5.3 7.4 8.0 16.8 10.2 4.4 TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 153.7;HMC-1: 70.6;HUVEC TERT2: 31.2;JURKAT: 60.0;K-562: 48.9;MOLT-4: 26.3;TIME: 34.4" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" 7.5 2.5 4.9 1.0 4.5 29.4 6.3 4.7 4.4 2.9 3.0 2.1 0.8 2.9 0.6 1.8 3.5 2.3 5.9 4.6 4.6 4.4 1.5 13.0 1.4 6.5 7.1 1.2 0.9 0.9 1.7 6.9 6.8 2.1 1.3 0.2 1.1 0.8 2.1 1.7 3.1 2.7 6.9 7.1 1.8 0.9 6.4 0.4 5.4 2.5 0.7 2.4 2.5 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.2 0.1 153.7 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 0.0 0.0 31.2 60.0 48.9 0.1 0.0 0.0 26.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.1 34.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.5 4.9 4.5 4.7 4.4 4.6 4.6 6.5 7.1 6.8 6.9 6.4 6.8 23.9 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.5 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.1 18.1 0.0 151.5 0.0 0.0 0.3 0.6 0.0 0.0 36.8 0.0 26.7 0.1 10.6 0.0 0.1 0.0 0.0 1.6 1.5 18.2 0.0 4.8 1.8 29.0 0.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 1.3 0.4 0.1 1.0 0.0 2.0 0.0 0.0 0.0 TCAF2 "FAM115C, FAM139A, FLJ40722, GATD9" ENSG00000170379 "TRPM8 channel associated factor 2" A6NFQ2 7 143620952-143730409 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.2;Hepatocytes: 12.3;Syncytiotrophoblasts: 15.7;T-cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 10.6;HUVEC TERT2: 11.6;TIME: 18.5;U-87 MG: 13.8" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" "unprognostic (6.59e-2)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (8.86e-3)" "prognostic unfavorable (9.53e-5)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.36e-1)" "unprognostic (2.04e-2)" "unprognostic (3.98e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.17e-6)" "unprognostic (7.19e-2)" "unprognostic (4.02e-2)" "unprognostic (5.41e-3)" "unprognostic (2.85e-2)" 2.1 1.9 1.5 4.0 1.5 4.1 5.8 4.6 3.4 4.0 0.0 1.2 1.0 1.7 0.8 9.2 1.9 2.2 1.2 1.5 1.9 2.6 4.5 3.7 4.2 2.2 2.5 2.6 2.0 2.1 2.6 5.2 2.5 2.8 1.1 3.2 3.7 1.2 0.7 4.3 2.4 1.5 0.7 2.8 2.0 1.6 1.7 3.3 1.3 0.7 3.4 2.8 5.9 3.2 5.5 0.3 0.1 0.2 1.0 1.0 2.0 1.5 3.1 0.7 2.2 0.1 0.3 0.2 2.1 1.3 0.5 0.8 0.1 3.0 2.3 10.6 0.5 0.8 0.6 0.1 1.2 0.3 0.4 2.9 1.3 0.3 0.9 2.1 11.6 0.7 3.0 5.1 4.3 0.8 0.6 0.8 0.2 5.0 2.7 0.4 2.1 2.4 0.0 1.9 0.1 0.1 0.5 4.3 0.2 0.8 1.9 0.2 18.5 1.3 0.9 5.5 0.4 7.7 2.6 0.1 13.8 0.4 3.2 5.7 0.2 0.2 2.9 0.2 3.1 1.9 4.8 3.1 0.2 1.8 4.2 3.3 0.9 2.2 0.2 0.7 5.6 1.2 1.5 1.5 4.6 3.4 1.5 1.9 2.2 2.5 2.5 0.7 1.7 3.2 0.5 0.0 1.8 0.0 4.5 0.0 1.3 0.0 3.4 0.7 5.6 3.4 0.4 0.0 1.8 0.0 0.0 16.2 5.6 0.2 0.0 0.9 1.0 0.8 1.4 3.5 0.0 0.4 3.7 0.4 4.9 2.4 2.6 1.3 2.5 0.3 0.7 12.3 2.0 0.0 3.6 0.2 0.0 1.6 0.0 1.1 1.8 1.8 0.0 0.0 0.4 2.1 7.2 1.5 0.1 1.3 0.1 0.7 5.0 2.1 2.1 0.4 0.0 0.1 0.0 2.3 1.1 3.5 2.0 4.9 0.0 15.7 9.1 0.8 0.4 1.1 TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late spermatids: 89.0;Spermatocytes: 103.7" "Cancer enhanced" "Detected in many" "testis cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.0;TIME: 1.4" "Not detected" "Not detected" HPA054327 Approved Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA054327: AB_2682452" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.33e-3)" "unprognostic (9.69e-3)" "unprognostic (5.80e-3)" "unprognostic (2.99e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (8.04e-5)" "unprognostic (1.62e-1)" 11.1 4.5 3.7 0.5 3.7 0.1 6.8 3.1 3.7 5.1 3.3 2.8 0.7 4.2 2.3 2.4 6.5 1.6 7.6 3.3 3.2 3.5 4.5 8.1 0.8 3.2 3.5 10.1 0.9 0.9 2.6 1.7 3.3 3.9 1.3 0.1 1.8 1.2 1.9 2.3 3.5 1.8 3.2 8.9 1.9 55.6 3.7 0.5 11.0 1.4 0.4 3.9 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.7 3.1 3.7 3.3 3.2 3.2 3.5 3.3 3.2 3.7 3.1 10.0 3.2 6.7 4.9 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.5 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.8 0.0 0.1 8.2 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 1.3 0.7 6.1 0.4 0.4 0.0 0.5 0.0 0.0 4.0 2.1 89.0 2.5 1.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 103.7 16.5 0.1 0.3 0.0 0.0 0.1 0.0 0.0 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 22.0;Astrocytes: 25.5;Basal respiratory cells: 16.5;Endothelial cells: 29.9;Hepatic stellate cells: 17.2;Microglial cells: 17.8;Spermatocytes: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.9;HBEC3-KT: 19.9;hTCEpi: 19.0;hTERT-HME1: 19.5;HUVEC TERT2: 40.6;LHCN-M2: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012611, CAB020796" Uncertain Supported Cytosol "Intracellular and membrane" No No 1400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB020796: , HPA012611: AB_1857990" "unprognostic (1.21e-1)" "unprognostic (7.54e-3)" "unprognostic (3.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-1)" "unprognostic (6.10e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-3)" "unprognostic (8.44e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-2)" "unprognostic (4.90e-2)" 10.0 2.0 7.9 1.0 7.4 0.2 8.7 5.5 8.5 5.3 4.5 2.8 0.7 5.2 2.8 3.1 5.1 3.3 9.0 8.2 5.5 3.0 2.2 11.5 2.1 6.0 5.4 2.1 1.4 1.4 3.4 11.3 5.8 4.1 1.4 6.8 3.9 1.9 4.5 6.3 2.7 4.7 5.6 5.9 2.1 2.1 6.4 1.4 5.0 10.4 1.6 3.8 4.5 5.9 0.9 3.9 0.5 3.5 3.1 10.3 0.8 8.4 4.1 3.2 5.1 0.1 0.7 0.3 1.0 19.9 3.1 4.4 0.0 19.9 4.9 9.3 2.9 0.5 0.0 0.0 1.9 2.1 0.6 4.1 19.0 15.4 19.5 1.8 40.6 1.2 0.0 0.3 18.6 0.0 0.7 0.4 0.3 0.2 0.9 0.6 4.3 0.0 4.5 0.2 0.1 0.7 0.2 0.1 0.8 0.2 0.4 0.3 9.6 1.0 1.7 0.0 6.3 0.6 0.1 0.1 1.8 0.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.4 5.5 8.5 8.2 5.5 6.0 5.4 5.8 5.6 6.4 5.9 22.0 0.0 1.1 25.5 0.9 1.5 1.1 16.5 0.6 8.0 1.5 3.0 3.1 0.0 1.8 1.8 2.1 5.4 3.6 0.3 3.9 0.3 1.4 0.8 1.0 29.9 0.0 0.0 3.5 0.6 1.8 6.4 1.1 0.7 0.0 1.5 17.2 2.0 3.1 0.0 3.1 0.3 0.0 1.6 1.6 0.6 3.4 0.6 5.4 17.8 0.4 1.2 1.0 3.0 0.9 0.4 0.2 3.8 0.6 1.8 0.4 0.8 1.3 3.2 6.6 4.4 2.3 18.5 10.1 1.0 1.6 3.4 0.9 0.6 0.3 0.4 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TM4SF1 "L6, M3S1" ENSG00000169908 "Transmembrane 4 L six family member 1" P30408 3 149369022-149377692 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 5463.1;Endothelial cells: 1843.0;Pancreatic endocrine cells: 2557.3;Prostatic glandular cells: 2717.0;Urothelial cells: 4902.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 703.8;hTERT-RPE1: 925.5;HUVEC TERT2: 633.3;LHCN-M2: 687.7;OE19: 672.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002760, HPA002823" Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB002760: , HPA002823: AB_1079221" "unprognostic (1.94e-1)" "unprognostic (2.25e-2)" "unprognostic (5.20e-2)" "unprognostic (4.79e-2)" "unprognostic (2.89e-2)" "unprognostic (2.47e-3)" "unprognostic (3.85e-3)" "unprognostic (2.74e-2)" "unprognostic (5.09e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (4.67e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.43e-6)" 365.9 71.3 41.9 50.5 43.1 2.6 192.8 44.1 68.2 82.6 65.6 61.6 38.3 74.9 58.2 210.9 74.7 237.6 181.7 42.2 45.2 155.1 92.6 229.8 25.2 45.1 43.9 49.7 211.7 19.9 20.2 194.6 47.7 79.9 59.9 6.0 180.9 32.0 50.2 63.5 62.2 94.6 45.4 120.5 129.7 19.5 53.5 17.0 72.5 64.2 60.2 150.9 115.5 45.9 367.9 401.9 0.0 1.0 108.4 422.2 0.6 115.2 455.5 23.9 8.8 159.7 703.8 0.1 351.3 23.5 545.5 434.0 1.9 80.0 22.9 0.9 0.0 3.9 391.8 521.8 39.4 0.0 0.5 40.0 19.1 169.7 81.5 925.5 633.3 0.0 0.3 0.8 687.7 0.5 0.0 0.7 1.5 672.9 170.7 0.2 0.9 0.8 449.3 54.8 0.2 0.5 46.8 25.1 4.4 6.0 0.8 1.7 404.7 233.6 38.9 4.8 244.3 0.5 0.7 1.1 337.4 0.4 62.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.9 43.1 44.1 68.2 42.2 45.2 45.1 43.9 47.7 45.4 53.5 45.9 1131.0 576.9 342.3 0.3 7.5 278.0 5463.1 668.3 272.6 0.1 956.5 363.1 24.0 274.5 984.3 57.0 0.0 0.8 17.0 176.6 0.0 1383.5 5.2 514.1 168.0 1843.0 39.2 15.6 0.0 1600.9 0.9 297.2 147.8 1807.5 31.5 0.2 1263.6 21.8 1.9 0.0 0.0 15.9 382.5 27.8 222.1 11.3 255.7 35.6 300.6 30.9 26.4 0.0 0.0 0.0 0.3 2557.3 251.8 176.0 11.1 2717.0 0.3 1.2 238.5 0.0 322.1 37.7 311.0 6.6 1.4 925.8 253.7 1.4 44.1 44.2 46.6 4902.9 TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 47.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;granulocytes: 44.4;Hofbauer cells: 50.9;Kupffer cells: 37.8;Langerhans cells: 46.4;Macrophages: 45.9;Microglial cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 76.6;eosinophil: 195.8;neutrophil: 118.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 195.8" "Cell line enhanced" "Detected in some" "HEL: 23.2;HHSteC: 49.6;HUVEC TERT2: 27.7;JURKAT: 36.4;TIME: 68.3;U-698: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "HPA016051: AB_2203924, HPA056857: AB_2683259" "unprognostic (8.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-2)" "unprognostic (4.67e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.15e-2)" "unprognostic (4.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" 6.5 3.9 5.4 5.2 6.0 5.3 4.6 7.7 8.8 3.3 6.3 2.6 2.0 2.8 2.1 3.1 2.8 3.7 9.6 5.2 5.6 1.9 2.3 10.7 5.7 6.8 6.0 1.7 1.2 1.8 0.9 7.8 6.6 2.1 2.6 2.8 2.9 1.3 47.3 1.8 2.6 3.9 6.9 6.2 2.1 3.6 5.4 2.2 10.4 21.8 3.0 3.8 1.5 7.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.3 5.6 0.0 0.2 0.0 0.3 0.1 1.0 0.0 0.3 0.0 3.7 0.0 0.0 0.0 0.3 23.2 0.0 0.0 49.6 1.6 0.1 0.2 0.0 0.0 0.1 0.3 27.7 36.4 0.9 0.0 0.4 0.0 0.0 3.0 0.6 0.0 0.0 0.0 4.2 0.0 0.1 0.4 1.2 0.3 0.2 0.0 1.9 0.5 0.0 14.9 68.3 0.6 0.9 0.1 0.3 2.1 0.0 17.0 0.1 3.4 0.1 76.6 31.7 195.8 5.0 13.4 0.0 0.3 0.5 0.8 18.9 0.9 0.1 0.8 118.1 5.0 6.4 2.6 0.0 11.8 5.4 6.0 7.7 8.8 5.2 5.6 6.8 6.0 6.6 6.9 5.4 7.6 30.5 0.0 6.0 2.9 0.9 2.4 0.1 0.4 0.6 1.6 0.5 1.8 1.2 1.5 0.8 0.0 0.0 0.3 7.5 0.0 0.0 0.2 13.1 0.6 0.2 16.7 0.0 4.4 18.7 2.0 0.4 1.5 0.0 0.3 44.4 0.0 7.9 0.1 50.9 0.0 22.4 0.0 0.0 37.8 46.4 7.4 0.9 45.9 3.6 46.9 19.4 0.5 16.5 2.0 1.9 0.4 0.0 0.0 0.7 0.1 0.0 0.0 1.4 1.3 0.0 1.4 0.6 13.1 7.5 0.1 1.7 0.3 4.2 0.1 0.0 0.1 TMOD3 UTMOD ENSG00000138594 "Tropomodulin 3" Q9NYL9 15 51829628-51947295 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 397.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001849 Approved Approved "Actin filaments,Cytosol" NA NA 1200000 "Cluster 42: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Actin filaments" "HPA001849: AB_1080313" "unprognostic (6.31e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.39e-1)" "unprognostic (7.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (7.06e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (5.58e-3)" 12.2 7.4 4.8 13.6 4.9 9.7 9.4 4.2 5.3 11.4 6.7 15.4 15.5 9.9 10.3 43.4 13.2 11.8 6.9 4.2 3.7 13.5 13.7 21.7 12.8 5.0 5.2 6.9 8.0 7.3 3.4 21.9 4.9 7.5 15.4 3.6 12.8 9.8 3.4 15.0 16.0 9.6 4.9 13.7 16.9 3.4 5.8 12.6 9.6 6.4 19.5 16.4 18.7 5.0 59.4 56.0 22.3 5.8 21.6 35.9 25.8 26.1 35.5 26.7 23.8 21.8 42.4 13.9 21.7 28.0 18.9 82.3 20.7 58.5 33.9 23.8 9.1 20.6 62.6 17.9 24.0 26.6 22.1 24.2 55.7 21.5 66.2 32.9 47.7 20.0 22.3 20.6 32.6 43.9 17.8 17.7 12.4 36.3 10.3 21.0 26.7 37.8 43.5 41.5 5.4 14.6 43.5 28.9 15.6 29.7 19.7 21.0 53.8 33.9 22.6 27.8 31.3 12.5 39.5 15.6 21.7 48.0 20.4 47.6 27.9 41.4 22.7 34.7 20.2 20.4 19.8 20.3 20.6 23.8 16.7 15.7 45.5 18.8 39.3 29.0 26.0 16.7 4.8 4.9 4.2 5.3 4.2 3.7 5.0 5.2 4.9 4.9 5.8 5.0 147.9 397.4 68.2 23.8 43.5 106.9 91.4 66.3 70.6 8.3 38.8 27.3 45.8 30.0 112.7 42.3 14.6 56.1 63.3 117.4 41.1 85.8 38.9 67.5 87.6 131.6 18.6 50.9 29.4 71.6 66.3 84.1 71.9 91.3 143.0 28.8 101.4 52.9 53.9 15.2 25.5 52.0 36.7 51.7 74.1 99.3 45.1 88.4 32.0 33.7 67.5 19.2 60.8 17.1 17.1 152.6 79.0 44.4 44.1 160.3 65.5 56.5 82.2 12.6 13.1 35.2 58.0 14.5 13.9 137.0 132.1 51.3 74.3 57.4 59.9 215.9 TNFAIP1 "B12, B61, BTBD34, EDP1, MGC2317" ENSG00000109079 "TNF alpha induced protein 1" Q13829 17 28335602-28347009 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 166.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013333, HPA014641" Uncertain Approved Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Nucleoli "HPA013333: AB_1858160, HPA014641: AB_1858159" "unprognostic (4.42e-1)" "unprognostic (1.54e-2)" "unprognostic (4.32e-2)" "prognostic unfavorable (7.48e-5)" "unprognostic (2.29e-1)" "unprognostic (4.97e-3)" "unprognostic (3.21e-1)" "unprognostic (1.94e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-2)" "unprognostic (8.27e-3)" "unprognostic (1.43e-2)" "unprognostic (4.21e-3)" "unprognostic (2.49e-2)" "unprognostic (2.04e-1)" "unprognostic (4.09e-1)" "unprognostic (7.02e-2)" 36.1 30.4 32.4 19.3 31.1 8.1 30.3 28.5 32.0 22.0 38.6 19.9 17.7 21.7 14.9 39.6 19.2 28.9 46.7 30.9 29.1 35.9 54.8 40.9 17.0 30.3 30.1 17.4 37.6 23.0 17.5 44.7 29.4 20.5 16.9 26.3 23.9 20.5 23.3 29.0 17.7 30.9 28.9 50.2 25.4 17.2 35.7 22.0 24.0 23.8 19.5 35.1 23.4 28.9 43.3 61.3 40.2 28.4 34.3 30.1 39.0 50.4 62.4 60.6 47.6 166.1 25.8 8.7 34.4 67.0 29.4 49.1 22.3 86.9 46.5 24.0 28.0 7.7 66.0 24.2 45.9 13.5 12.5 38.9 99.7 47.7 37.0 56.9 71.7 17.4 20.0 12.8 28.8 25.8 25.6 7.4 9.3 36.4 22.3 11.3 50.8 15.5 89.5 45.9 29.3 31.7 62.3 102.5 25.8 55.8 42.9 11.4 76.4 44.2 43.7 34.4 39.3 20.8 18.7 9.3 34.3 9.0 28.5 1.7 7.2 9.5 6.5 7.0 7.7 5.3 4.7 5.9 9.3 3.9 4.5 5.5 2.5 9.1 8.7 4.5 4.3 5.0 32.4 31.1 28.5 32.0 30.9 29.1 30.3 30.1 29.4 28.9 35.7 28.9 66.6 38.5 12.9 5.5 4.6 24.6 47.5 32.0 12.5 25.6 18.2 11.9 21.8 20.0 17.5 22.0 16.7 31.5 6.2 14.3 23.5 60.5 40.1 23.0 13.9 62.4 17.4 7.4 11.7 82.5 34.9 13.5 12.8 30.2 7.0 14.0 60.3 29.5 11.0 11.8 7.5 11.0 10.2 12.5 12.1 6.9 7.8 7.0 0.0 9.4 30.1 10.0 4.1 7.1 7.2 112.9 15.1 7.9 7.1 46.9 13.6 16.9 20.2 9.8 13.1 10.9 22.3 5.4 5.6 15.9 28.4 69.2 5.0 18.1 9.7 43.0 TNFRSF10A "Apo2, CD261, DR4, TRAILR-1, TRAILR1" ENSG00000104689 "TNF receptor superfamily member 10a" O00220 8 23190452-23225102 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050958, HPA054475" Approved Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA050958: AB_2681290, HPA054475: AB_2682500" "unprognostic (3.66e-1)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (4.89e-2)" "unprognostic (9.44e-2)" "unprognostic (8.39e-2)" "unprognostic (5.32e-2)" "unprognostic (2.18e-2)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (1.49e-1)" "unprognostic (1.99e-3)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-1)" "unprognostic (2.87e-1)" 5.7 2.3 2.6 9.9 2.5 9.3 5.7 2.2 2.7 4.3 2.2 7.0 6.2 2.9 1.1 8.4 4.1 8.2 3.0 2.0 2.4 3.8 5.3 6.6 13.4 3.4 2.8 0.8 2.4 2.7 0.8 7.1 3.1 2.9 7.1 0.2 4.8 2.5 1.5 4.9 6.5 3.9 2.8 6.8 6.5 0.5 3.4 6.4 3.0 2.8 14.0 10.8 5.8 2.8 18.7 33.0 1.7 0.1 1.2 6.4 0.1 3.8 2.3 1.9 5.2 25.4 31.8 42.9 41.9 2.4 9.1 34.6 29.5 47.2 3.1 10.7 0.2 22.7 20.4 14.7 16.2 12.3 20.7 11.0 38.2 41.1 35.0 5.5 21.9 1.4 35.7 14.9 8.9 14.5 0.4 7.8 22.6 33.0 20.0 0.3 0.0 31.2 24.4 39.5 0.9 1.1 9.3 23.0 0.0 6.9 12.3 9.3 31.3 0.1 0.2 1.8 0.1 17.4 26.7 32.7 0.2 3.9 0.5 2.8 6.1 5.7 5.0 2.6 13.8 15.3 16.1 10.2 6.3 19.1 15.7 9.2 0.6 6.1 2.6 0.0 20.8 6.5 2.6 2.5 2.2 2.7 2.0 2.4 3.4 2.8 3.1 2.8 3.4 2.8 21.5 3.2 8.7 0.7 22.3 23.6 20.7 9.1 21.6 0.2 8.2 7.1 1.1 7.2 15.5 11.0 0.0 0.1 3.1 10.1 0.0 10.1 0.1 8.6 1.9 16.6 2.4 1.3 0.4 4.0 0.4 2.2 10.2 23.9 7.6 0.7 2.9 5.1 3.1 0.0 0.4 7.0 8.2 2.2 12.7 0.0 0.0 8.5 3.6 9.4 4.2 0.0 2.1 1.0 0.5 20.3 7.3 0.0 14.0 11.7 4.5 2.9 5.7 0.0 0.0 0.9 1.1 0.0 0.5 25.6 27.4 0.0 12.8 0.1 9.1 27.4 TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.3" "Cell type enhanced" "Detected in some" "Adipocytes: 7.1;Early spermatids: 3.5;Kupffer cells: 5.3;Langerhans cells: 3.3;Late spermatids: 9.8;Macrophages: 5.8;monocytes: 5.1" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 96.6" "Lineage enriched" "Detected in many" 5 "monocytes: 96.6" "Cell line enriched" "Detected in some" 21 "HDLM-2: 552.9" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" 5.3 0.0 0.1 3.1 2.3 0.6 3.5 0.0 0.6 0.2 0.1 0.4 0.0 0.8 0.0 0.2 0.9 0.6 1.9 0.0 0.2 0.3 0.0 0.9 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.7 0.2 0.2 0.1 0.0 0.3 0.1 0.9 0.9 0.7 0.5 0.1 1.4 2.5 1.4 0.7 1.0 0.1 1.2 1.1 0.9 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.4 0.0 0.1 0.8 11.7 0.0 0.0 0.0 0.0 0.0 0.1 552.9 0.1 0.0 0.1 0.0 0.0 10.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.7 26.3 1.5 0.0 0.0 1.5 0.2 21.7 0.0 0.4 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 1.4 1.4 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 17.6 1.0 0.1 59.4 0.3 0.1 0.1 0.0 8.7 0.0 0.0 0.0 18.3 0.0 96.6 2.3 0.8 8.5 0.1 2.3 0.0 0.6 0.0 0.2 0.2 0.1 0.2 0.1 0.7 0.2 7.1 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.1 0.5 2.2 0.0 0.0 0.6 0.0 0.2 1.1 2.6 0.1 0.0 0.1 2.2 0.1 1.5 0.0 0.5 0.0 0.0 5.3 3.3 9.8 0.3 5.8 0.0 1.0 5.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 1.0 0.0 0.1 0.3 0.4 0.2 0.0 0.1 TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.3;Hepatic stellate cells: 93.1;Leydig cells: 141.7;Peritubular cells: 114.0;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 114.2;ASC TERT1: 78.1;HHSteC: 59.9;HSkMC: 86.2;hTERT-RPE1: 61.9;TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034659: AB_10603349" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.21e-3)" "unprognostic (1.86e-1)" "unprognostic (3.59e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-2)" "unprognostic (8.97e-3)" "prognostic favorable (1.72e-4)" "prognostic favorable (9.32e-4)" "unprognostic (4.46e-2)" "unprognostic (1.09e-2)" "unprognostic (8.46e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" 156.3 66.9 59.3 14.8 66.2 0.3 121.6 46.4 57.8 121.2 33.3 79.0 14.4 98.8 14.0 28.3 121.0 32.5 99.6 43.7 49.2 67.3 66.5 83.4 15.8 58.0 63.5 104.1 34.6 17.0 43.3 33.1 54.0 66.3 11.5 6.0 35.7 41.1 69.0 42.1 56.7 28.5 50.8 79.5 58.2 15.9 58.3 7.2 80.6 58.8 6.4 82.6 81.1 57.9 2.0 21.2 2.7 2.2 114.2 78.1 0.7 11.8 27.1 6.2 3.2 1.4 5.7 0.1 25.3 32.1 2.6 1.5 0.1 7.8 2.4 0.5 0.8 0.4 25.5 11.3 59.9 0.3 0.5 86.2 0.3 7.9 4.7 61.9 36.3 0.4 0.6 0.3 24.9 5.1 0.2 0.4 1.9 1.4 5.8 0.7 6.6 0.3 8.2 0.4 1.2 2.7 4.4 2.4 8.8 1.6 26.1 0.7 52.1 12.9 14.8 4.7 2.0 0.6 0.3 0.1 20.4 0.3 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.3 66.2 46.4 57.8 43.7 49.2 58.0 63.5 54.0 50.8 58.3 57.9 109.3 3.2 25.7 33.3 0.5 0.0 6.8 0.0 5.2 21.1 15.1 13.0 7.9 10.0 2.5 5.5 0.0 0.5 0.9 0.4 3.9 5.8 2.8 4.4 41.1 69.6 1.2 2.7 3.1 4.4 0.4 40.5 2.0 14.5 0.0 7.7 93.1 37.5 2.4 30.3 7.8 3.9 0.0 4.4 0.0 7.2 141.7 2.9 0.0 31.9 0.1 29.6 0.0 46.3 35.6 2.4 9.0 114.0 1.8 4.5 2.1 2.6 1.5 11.3 151.2 51.3 64.7 4.2 4.4 1.3 0.0 0.8 1.4 2.6 1.8 2.1 TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 542.1" "Cell type enhanced" "Detected in many" "Astrocytes: 274.9;Excitatory neurons: 215.6;Hepatic stellate cells: 407.3;Inhibitory neurons: 249.8;Oligodendrocyte precursor cells: 353.4" "Cancer enhanced" "Detected in all" "glioma: 71.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 109.5;JURKAT: 380.9;MOLT-4: 239.7;SCLC-21H: 129.0;U-266/70: 163.2" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB062566: AB_2665608, CAB068245: AB_2665609, HPA003140: AB_1078454" "unprognostic (1.12e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.06e-2)" "unprognostic (3.90e-3)" "unprognostic (3.88e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.54e-1)" "prognostic favorable (5.48e-7)" "unprognostic (5.65e-3)" "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" 56.1 125.6 355.5 17.2 433.8 1.3 33.5 369.5 542.1 42.6 271.3 68.1 36.3 43.8 37.6 33.6 36.5 25.8 70.3 413.7 334.3 56.2 45.0 67.4 41.1 290.3 298.8 19.6 19.8 13.9 28.0 25.1 283.6 18.8 64.6 286.9 12.5 26.8 153.9 19.4 34.0 51.1 291.7 96.3 14.5 4.8 331.7 15.7 51.3 232.3 28.9 29.7 16.9 384.6 0.1 0.0 2.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 3.8 1.6 0.0 109.5 14.9 0.5 0.0 67.2 0.0 0.1 1.2 1.5 0.0 0.0 0.0 0.0 0.0 380.9 0.0 0.4 1.7 0.4 239.7 0.0 11.2 0.1 0.0 14.6 4.6 0.0 11.0 1.4 129.0 14.4 0.0 0.0 4.3 6.5 0.0 0.3 0.0 0.1 3.1 0.1 1.0 163.2 54.8 0.0 5.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 355.5 433.8 369.5 542.1 413.7 334.3 290.3 298.8 283.6 291.7 331.7 384.6 116.1 12.8 23.8 274.9 1.1 10.6 2.7 6.3 6.2 92.0 1.0 3.8 34.1 1.5 4.6 11.0 43.8 0.4 0.2 69.1 23.5 0.4 0.0 2.1 1.6 153.3 18.7 5.3 215.6 0.6 0.4 14.0 4.6 5.6 10.1 108.1 407.3 4.8 45.1 97.6 249.8 23.5 0.0 15.0 10.0 1.9 0.6 1.5 14.2 46.9 0.0 102.3 0.0 353.4 50.6 0.9 21.9 3.0 1.5 2.4 40.3 9.8 1.2 107.4 59.2 26.5 11.7 0.6 3.3 9.9 6.5 0.8 2.6 27.0 35.7 0.9 USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 41.5;Endothelial cells: 28.3;Hepatic stellate cells: 21.4;Ionocytes: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 10.9;HeLa: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" 8.8 1.9 5.0 1.6 4.9 2.9 8.2 7.2 5.2 2.9 4.1 1.9 1.9 3.6 1.1 1.3 3.1 1.7 12.6 5.0 4.1 4.5 1.2 6.9 2.6 4.6 4.5 1.4 4.8 0.8 1.2 5.6 5.1 2.3 0.5 1.1 2.0 0.9 6.2 2.1 2.2 1.3 3.3 3.5 1.7 1.0 5.1 0.5 4.5 4.8 0.5 2.8 2.3 4.6 0.6 0.9 1.7 0.4 0.0 0.0 10.9 0.3 0.0 0.0 0.0 1.9 0.9 2.9 3.4 0.0 0.1 1.2 0.1 0.2 0.0 0.7 1.3 0.7 5.0 1.1 0.0 2.4 2.4 0.3 0.0 0.2 0.2 0.6 3.2 1.1 1.4 1.5 0.0 0.1 0.4 2.4 1.3 0.3 2.7 1.4 0.2 0.7 0.0 1.3 1.1 0.7 0.7 0.7 0.2 0.9 1.3 0.9 1.9 1.8 0.5 1.5 1.0 2.6 0.9 2.8 0.6 1.5 0.6 2.0 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.7 0.1 1.0 0.9 0.8 1.6 0.7 0.2 0.8 0.8 0.5 5.0 4.9 7.2 5.2 5.0 4.1 4.6 4.5 5.1 3.3 5.1 4.6 41.5 3.2 0.5 0.7 0.0 0.5 0.9 0.1 0.6 0.3 0.5 0.1 6.7 0.0 0.7 0.0 0.0 1.1 3.1 0.2 0.0 0.1 0.7 0.7 0.8 28.3 0.0 0.0 0.4 0.6 0.9 0.9 0.0 1.5 1.3 0.1 21.4 0.3 0.1 0.0 0.5 0.2 20.3 0.6 1.2 0.2 0.6 0.3 5.4 6.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 1.3 0.1 1.7 0.0 2.2 1.5 0.2 0.4 0.2 1.0 4.5 0.7 0.3 0.0 0.8 VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.3;ovary: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Cone photoreceptor cells: 29.2;Hepatocytes: 16.4;Rod photoreceptor cells: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.2;Hep G2: 26.3;HSkMC: 13.4;REH: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Vesicles, Cytosol" "HPA040401: AB_2676963, HPA043921: AB_2678731" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-3)" "unprognostic (9.27e-4)" "unprognostic (1.21e-2)" "unprognostic (4.01e-4)" "unprognostic (3.04e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-4)" "unprognostic (7.20e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-1)" 2.8 1.1 0.6 0.1 0.9 1.6 1.5 0.3 1.6 2.9 0.0 0.6 0.3 1.3 0.6 0.9 3.5 0.6 0.8 0.7 0.7 0.5 14.3 0.3 0.2 0.5 1.2 7.9 0.3 0.1 0.6 2.4 0.4 1.0 0.4 0.8 0.9 0.5 0.7 0.7 0.4 0.4 0.0 0.4 0.4 1.8 0.5 2.5 0.8 0.4 0.1 0.6 1.2 0.2 0.0 0.1 1.5 0.2 0.2 1.8 0.6 0.2 2.0 0.0 0.3 7.2 0.0 0.5 0.0 0.4 0.1 0.0 2.3 0.0 0.1 0.4 0.0 0.8 0.0 26.3 1.2 0.0 0.3 13.4 0.6 0.7 0.0 0.1 2.3 3.3 0.2 0.3 0.3 0.1 5.5 0.0 2.2 0.0 0.0 14.0 0.2 0.0 0.1 0.1 0.6 1.0 0.0 0.1 0.7 2.4 0.9 0.0 0.8 0.3 0.3 0.5 0.2 0.2 0.6 1.2 0.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.3 1.6 0.7 0.7 0.5 1.2 0.4 0.0 0.5 0.2 2.1 3.2 1.7 19.2 0.3 1.8 1.8 3.8 3.4 3.6 1.7 0.5 1.0 1.5 2.3 0.0 29.2 1.0 0.5 0.2 0.0 0.1 0.5 2.9 1.0 5.5 1.8 6.1 7.5 0.5 5.0 2.6 0.0 1.8 3.8 6.5 2.5 16.4 1.2 0.0 5.8 0.1 2.0 3.5 2.4 0.8 6.8 2.6 1.8 2.8 2.3 2.3 1.0 2.5 1.4 0.0 0.0 1.9 0.4 1.1 0.1 0.3 5.4 21.1 0.0 0.9 1.1 1.1 3.4 1.3 2.3 4.4 0.9 7.7 0.3 0.7 WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 324.4" "Cell type enhanced" "Detected in some" "Adipocytes: 66.4;Cytotrophoblasts: 16.5;Endothelial cells: 38.5;Hofbauer cells: 43.1;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1345.3;non-classical monocyte: 1608.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 908.5;SK-MEL-30: 1012.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 49000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 100.7 67.9 40.3 185.6 44.4 70.5 65.4 40.1 45.5 35.9 45.2 67.8 44.8 39.6 70.3 54.4 50.8 48.7 157.6 44.2 56.0 83.6 47.9 207.5 139.0 72.0 52.6 21.2 47.5 39.2 63.4 324.4 65.3 49.1 72.0 37.8 49.5 38.3 74.7 28.4 67.7 76.2 47.6 110.6 70.1 67.7 55.0 61.7 159.9 67.0 86.2 107.7 30.7 44.9 91.2 85.7 54.6 319.1 78.7 110.7 87.3 117.4 220.7 232.1 301.4 57.4 80.2 101.7 105.5 277.4 59.7 151.1 158.8 130.3 153.1 154.4 48.3 64.1 60.9 72.3 908.5 184.9 101.6 126.9 186.9 141.3 290.1 74.5 225.0 66.1 202.8 255.0 107.5 178.0 64.3 87.1 55.4 94.1 152.2 51.4 86.5 64.9 119.3 80.8 145.7 84.9 69.4 58.7 1012.4 70.5 153.6 234.7 153.1 25.7 58.9 269.2 61.3 446.4 277.1 191.9 295.0 144.2 205.5 96.5 471.7 610.4 41.5 1345.3 38.4 71.4 34.5 38.4 337.9 68.0 24.8 28.6 170.9 44.5 1608.2 54.7 44.8 672.7 40.3 44.4 40.1 45.5 44.2 56.0 72.0 52.6 65.3 47.6 55.0 44.9 66.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 16.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 11.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 0.0