Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AAMDC "C11orf67, CK067, FLJ21035, PTD015" ENSG00000087884 "Adipogenesis associated Mth938 domain containing" Q9H7C9 11 77821109-77918432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 656.7" "Cell type enhanced" "Detected in all" "Theca cells: 385.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 143.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 280.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA037918, HPA037919" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA037918: AB_2675737, HPA037919: AB_2675738" "unprognostic (3.10e-2)" "unprognostic (9.04e-3)" "unprognostic (6.02e-2)" "unprognostic (4.67e-1)" "unprognostic (1.27e-1)" "unprognostic (3.51e-2)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-1)" "unprognostic (7.08e-2)" "unprognostic (1.90e-1)" "unprognostic (2.08e-1)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "unprognostic (3.84e-2)" 75.8 180.9 30.1 13.0 35.8 21.0 62.5 35.2 42.6 51.0 31.4 66.6 37.4 41.4 27.9 24.6 47.5 23.4 178.9 30.5 31.7 56.0 57.9 46.9 13.8 37.2 34.4 56.7 34.4 27.4 28.6 21.7 35.9 46.0 29.2 20.1 36.6 34.6 656.7 55.4 47.5 40.2 31.9 31.7 62.4 42.2 34.3 23.7 42.2 173.0 13.6 48.1 42.7 42.7 30.3 24.3 37.2 26.5 106.0 73.3 10.0 49.2 33.4 43.8 54.1 280.1 44.6 20.3 46.5 83.0 43.2 16.9 56.4 32.9 51.9 47.1 45.3 19.5 43.5 52.4 52.2 11.2 17.1 98.3 22.2 46.0 24.2 40.2 131.3 27.0 23.1 32.0 93.2 35.6 23.8 44.3 17.3 84.5 41.4 22.3 63.6 19.6 58.2 18.1 13.1 49.2 62.4 26.7 36.0 55.1 41.2 21.1 138.2 45.5 24.7 87.5 16.5 34.2 58.4 37.8 17.7 18.0 26.2 143.1 28.9 33.3 14.6 17.7 18.8 18.3 28.4 24.2 32.6 25.2 24.8 18.4 16.9 35.9 17.5 33.8 47.3 16.3 30.1 35.8 35.2 42.6 30.5 31.7 37.2 34.4 35.9 31.9 34.3 42.7 68.4 83.3 25.4 19.6 10.0 64.2 82.7 51.0 24.5 10.0 58.7 67.2 114.1 62.9 42.5 79.1 4.2 29.1 11.8 70.2 144.8 60.0 100.1 37.7 27.8 55.7 22.7 19.1 6.9 73.1 43.1 64.5 39.3 35.8 41.2 53.4 93.9 122.2 46.9 11.8 8.9 48.7 44.7 29.9 35.9 36.3 68.3 22.5 83.6 8.4 56.2 101.3 16.5 18.1 24.8 70.2 132.2 64.3 10.2 46.6 160.3 200.8 50.1 13.9 46.0 53.5 65.8 154.0 85.4 29.2 100.7 15.7 14.8 385.5 61.0 71.2 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABCC8 "ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2" ENSG00000006071 "ATP binding cassette subfamily C member 8" Q09428 11 17392498-17476879 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pancreas: 20.1;pituitary gland: 34.4" "Group enriched" "Detected in some" 4 "Astrocytes: 19.6;Bipolar cells: 39.0;Endometrial stromal cells: 17.9;Enteroendocrine cells: 22.0;Excitatory neurons: 48.2;Inhibitory neurons: 39.3;Oligodendrocyte precursor cells: 39.2" "Cancer enriched" "Detected in some" 9 "pancreatic cancer: 16.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 1.8;AN3-CA: 1.4;SCLC-21H: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011451, HPA042318" Approved Approved "Nucleoli,Golgi apparatus,Cytosol" No NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoli "Golgi apparatus, Cytosol" "CAB011451: , HPA042318: AB_2677947" "unprognostic (4.30e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (4.73e-2)" "unprognostic (9.48e-3)" "unprognostic (2.23e-1)" "unprognostic (4.46e-3)" "unprognostic (2.53e-3)" "unprognostic (6.04e-2)" "unprognostic (2.34e-2)" "unprognostic (8.72e-3)" "unprognostic (1.13e-1)" "unprognostic (2.22e-2)" "unprognostic (1.96e-2)" "unprognostic (6.88e-5)" "unprognostic (2.72e-2)" "unprognostic (1.85e-1)" 0.4 2.8 2.6 0.0 3.7 0.0 1.8 3.9 5.2 3.5 0.0 0.7 0.5 2.6 1.4 0.1 0.6 0.0 1.6 3.1 1.4 0.5 0.1 5.0 0.0 3.3 2.7 0.4 20.1 0.2 34.4 0.4 3.3 2.1 0.3 2.2 0.0 1.5 1.5 0.2 1.0 0.2 0.6 0.1 6.1 0.4 1.2 0.0 3.4 0.6 0.0 0.4 1.3 3.5 0.0 1.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.7 3.9 5.2 3.1 1.4 3.3 2.7 3.3 0.6 1.2 3.5 0.3 0.0 0.0 19.6 0.3 0.0 0.1 0.0 0.0 39.0 5.3 3.7 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.5 17.9 0.3 22.0 0.0 48.2 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 39.3 0.7 0.0 0.3 0.5 0.0 0.0 0.1 0.0 3.7 0.0 1.9 0.0 39.2 7.6 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.0 0.7 2.0 0.1 0.8 0.0 0.1 0.0 0.1 2.6 0.1 0.2 ABCD2 "ALDL1, ALDR, ALDRP" ENSG00000173208 "ATP binding cassette subfamily D member 2" Q9UBJ2 12 39550033-39619803 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.7;brain: 8.9" "Cell type enhanced" "Detected in some" "Astrocytes: 71.5;Bipolar cells: 57.2;Excitatory neurons: 33.2;Inhibitory neurons: 34.2" "Cancer enriched" "Detected in single" 7 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in single" 4 "T-cells: 4.2" "Group enriched" "Detected in some" 6 "ASC diff: 11.6;HDLM-2: 16.9;Karpas-707: 29.0;SH-SY5Y: 17.3;U-266/70: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.26e-3)" "unprognostic (4.06e-4)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (2.06e-1)" "unprognostic (7.31e-5)" "unprognostic (3.42e-2)" "unprognostic (2.90e-2)" "unprognostic (8.06e-3)" "unprognostic (3.43e-2)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-4)" "unprognostic (5.04e-2)" "unprognostic (8.04e-2)" "unprognostic (1.13e-1)" "unprognostic (6.74e-2)" 15.7 1.7 1.5 1.7 2.2 0.2 2.8 8.9 5.2 5.3 0.0 0.7 0.5 2.7 0.2 0.4 2.7 0.5 4.2 2.1 2.1 0.5 0.1 0.5 2.8 2.2 3.3 0.1 0.1 0.0 0.5 0.0 2.4 0.4 0.7 5.9 2.6 0.6 0.1 0.1 0.7 2.6 1.3 1.6 0.7 0.2 3.6 1.4 0.2 0.3 1.6 0.9 0.6 1.4 0.0 0.0 0.1 0.0 11.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 16.9 0.0 0.1 0.0 0.0 0.6 0.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 9.8 1.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 1.2 0.5 2.8 3.7 0.1 0.3 3.2 4.2 0.1 0.9 0.0 0.6 3.6 1.2 1.5 2.2 8.9 5.2 2.1 2.1 2.2 3.3 2.4 1.3 3.6 1.4 0.4 0.0 0.0 71.5 2.6 0.0 0.0 0.0 0.0 57.2 0.3 0.3 10.9 0.0 0.0 0.0 6.2 0.0 3.8 0.1 0.0 0.0 0.3 0.2 0.5 0.2 0.0 0.0 33.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.1 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.5 1.1 2.2 0.0 13.0 1.3 0.0 0.0 0.7 5.9 0.0 0.0 0.9 2.4 2.3 0.0 0.4 2.5 0.2 0.1 0.0 0.0 0.0 7.8 0.6 0.1 0.0 ABHD1 "FLJ36128, LABH1" ENSG00000143994 "Abhydrolase domain containing 1" Q96SE0 2 27123789-27130812 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 21.6" "Group enriched" "Detected in many" 9 "Early spermatids: 295.1;Late spermatids: 1030.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.5;T-47d: 3.3;U-266/70: 3.0;U-266/84: 2.8" "Low region specificity" "Detected in all" HPA044390 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA044390: AB_10959380" "unprognostic (1.20e-3)" "unprognostic (6.07e-3)" "unprognostic (7.71e-4)" "unprognostic (1.63e-2)" "unprognostic (6.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-3)" "unprognostic (2.75e-1)" "unprognostic (1.76e-1)" "unprognostic (9.09e-4)" "unprognostic (9.76e-2)" "unprognostic (1.70e-2)" "unprognostic (6.88e-2)" "unprognostic (4.06e-2)" "unprognostic (3.09e-2)" "unprognostic (7.97e-2)" 1.2 0.6 0.8 0.1 0.7 0.0 0.5 1.5 1.1 0.1 0.3 0.1 0.0 0.3 0.4 0.1 0.2 0.2 0.5 0.7 0.8 0.3 3.3 0.1 0.2 0.9 0.7 0.4 0.1 0.4 0.2 0.0 0.9 0.7 0.0 0.4 1.5 0.2 1.9 0.0 0.1 0.3 0.9 0.1 0.2 21.6 0.9 0.0 0.4 1.7 0.1 0.0 0.0 0.9 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.2 3.0 2.8 0.0 0.1 0.1 0.1 0.0 0.2 0.8 0.6 0.0 0.2 0.5 0.3 0.3 0.0 0.3 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.8 0.7 1.5 1.1 0.7 0.8 0.9 0.7 0.9 0.9 0.9 0.9 0.8 0.0 0.0 4.9 1.0 0.0 3.3 0.0 2.8 5.1 1.9 2.8 3.1 1.5 0.0 0.0 8.4 0.2 0.9 0.2 0.0 0.3 295.1 0.4 0.6 1.9 0.0 3.2 0.6 0.2 0.0 1.3 0.0 0.5 1.3 1.6 2.5 3.9 0.1 0.0 0.8 0.2 0.0 0.3 0.3 1030.5 6.5 1.2 0.0 1.9 0.5 8.1 3.1 2.0 2.2 0.0 0.0 5.7 0.5 3.6 0.2 3.0 0.7 4.9 0.0 2.4 1.2 70.5 3.9 0.3 0.3 0.0 1.8 0.3 0.2 2.2 ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10, depalmitoylase" Q9NUJ1 3 111979010-111993368 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" No No 71000 "Cluster 46: Basophils - DNA binding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA036991: AB_2675420, HPA036992: AB_10672345, HPA066081: AB_2685610" "unprognostic (1.65e-1)" "prognostic favorable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favorable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" 11.0 21.9 23.0 10.6 25.3 10.9 15.0 24.5 29.3 11.3 22.9 14.1 11.7 11.1 50.8 8.2 14.9 10.1 25.0 23.9 24.6 49.4 34.4 10.1 17.9 23.5 23.2 19.8 13.7 16.7 27.9 10.8 23.7 20.4 14.7 27.0 25.5 13.7 14.1 10.0 10.3 10.0 24.4 14.6 14.9 16.4 26.3 21.8 31.1 19.6 16.2 9.5 8.3 25.3 40.2 34.1 36.4 12.0 20.5 27.5 19.8 41.4 21.5 33.0 31.7 35.3 22.4 36.0 22.6 17.2 22.7 21.6 16.3 23.0 44.9 12.1 20.6 29.7 15.4 30.7 16.3 60.3 30.4 16.9 16.7 17.0 42.4 22.7 35.9 42.1 13.9 14.9 36.7 13.7 56.9 27.9 23.7 43.8 53.2 50.9 23.4 16.7 34.6 17.1 24.6 17.9 33.2 23.7 39.8 14.3 26.8 21.8 20.6 19.7 25.3 14.4 21.7 23.6 9.0 61.4 20.1 32.4 21.5 29.4 16.5 25.2 9.8 21.6 16.8 26.2 12.2 11.3 28.1 21.6 15.4 13.9 2.5 11.4 17.3 17.8 13.2 16.1 23.0 25.3 24.5 29.3 23.9 24.6 23.5 23.2 23.7 24.4 26.3 25.3 9.1 0.0 7.2 11.1 19.7 7.0 10.2 12.1 14.2 21.8 12.7 10.9 26.1 7.2 12.4 11.0 8.4 19.2 16.1 7.0 35.2 5.2 1.0 11.1 10.3 8.8 12.1 24.2 16.0 7.8 14.9 12.3 12.8 6.8 9.5 9.5 10.0 26.2 14.1 42.1 16.2 13.4 6.1 19.5 7.0 3.0 10.5 11.0 10.6 15.0 10.7 20.4 12.3 14.6 15.6 5.4 4.0 7.5 25.0 5.1 7.0 42.5 19.5 16.2 0.0 7.9 8.9 29.7 37.0 13.6 8.2 5.5 14.6 19.2 12.1 4.5 ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981199 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 124.3;Rod photoreceptor cells: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 79.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038153, HPA056913" Approved Enhanced Vesicles NA NA 420000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038153: AB_2675868, HPA056913: AB_2683275" "unprognostic (4.15e-3)" "unprognostic (6.73e-2)" "unprognostic (1.98e-1)" "unprognostic (3.34e-2)" "unprognostic (2.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.92e-2)" "prognostic favorable (4.72e-4)" "unprognostic (3.96e-1)" "unprognostic (2.46e-2)" "unprognostic (5.52e-3)" "unprognostic (1.51e-2)" "unprognostic (1.97e-2)" "unprognostic (9.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.30e-2)" 23.5 48.6 65.2 8.3 64.5 13.5 18.4 72.3 78.0 25.1 67.6 18.1 10.6 15.0 28.3 8.4 24.2 12.1 36.1 64.8 69.3 35.3 26.1 14.3 11.4 59.6 60.0 27.1 26.6 27.1 49.6 8.9 59.7 19.0 6.9 43.5 23.2 14.5 34.8 7.6 12.9 7.5 59.2 14.6 17.7 13.2 69.4 11.5 32.8 39.1 8.4 19.4 16.7 59.8 6.9 12.9 8.2 24.7 79.8 39.9 4.5 9.0 14.8 10.6 14.3 14.8 27.0 7.8 6.0 22.4 12.1 6.2 9.0 10.0 3.4 25.1 10.0 22.7 37.4 50.0 22.4 31.4 29.0 37.9 6.6 9.0 4.6 23.7 13.8 14.6 9.3 25.4 16.8 7.8 14.5 31.8 4.7 32.4 30.4 10.3 4.2 73.9 20.7 10.6 16.8 26.1 22.5 4.7 13.5 1.7 7.1 33.7 8.2 9.6 10.4 23.4 10.7 37.0 37.4 6.6 18.1 49.6 14.1 6.9 20.3 15.2 94.0 12.7 96.5 49.0 80.9 83.5 36.2 41.5 73.7 79.0 2.1 45.5 8.6 46.0 88.4 54.9 65.2 64.5 72.3 78.0 64.8 69.3 59.6 60.0 59.7 59.2 69.4 59.8 15.9 6.4 21.7 0.0 20.2 9.7 25.1 29.0 4.0 90.8 21.0 22.9 24.3 20.0 20.8 33.1 25.0 10.3 29.6 7.1 33.2 15.5 4.7 23.5 18.0 14.1 40.2 2.5 0.0 12.4 15.3 36.9 4.6 14.9 15.2 12.8 17.2 16.2 29.3 58.9 0.0 14.0 24.4 14.2 18.5 24.9 88.0 14.6 12.4 0.0 7.4 59.9 41.2 0.0 0.0 17.1 5.6 33.1 16.3 17.0 13.8 124.3 29.5 115.2 19.7 24.7 16.8 18.2 57.8 1.8 5.5 4.9 28.9 20.6 15.3 19.5 ABLIM1 "ABLIM, LIMAB1, limatin" ENSG00000099204 "Actin binding LIM protein 1" O14639 10 114431113-114768061 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 875.6;Cardiomyocytes: 592.5;Peritubular cells: 413.0;Squamous epithelial cells: 481.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 139.1" "Group enriched" "Detected in many" 7 "B-cells: 52.2;NK-cells: 63.6;T-cells: 139.1" "Cell line enhanced" "Detected in many" "hTCEpi: 164.1;OE19: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038951, HPA038952" Approved Supported Cytosol NA NA 6000 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA038951: AB_10673017, HPA038952: AB_10670915" "unprognostic (2.25e-2)" "unprognostic (3.96e-2)" "unprognostic (2.91e-1)" "unprognostic (1.26e-1)" "unprognostic (5.89e-3)" "unprognostic (1.07e-2)" "unprognostic (3.19e-2)" "unprognostic (5.07e-2)" "unprognostic (4.39e-2)" "unprognostic (1.05e-1)" "unprognostic (3.20e-2)" "unprognostic (3.23e-1)" "prognostic favorable (2.72e-5)" "unprognostic (2.77e-2)" "unprognostic (1.92e-1)" "unprognostic (3.22e-1)" "unprognostic (5.87e-2)" 73.3 93.4 71.0 35.7 67.6 13.6 54.8 277.3 59.4 44.4 76.2 46.7 37.3 37.3 26.7 205.6 51.3 33.5 268.6 58.5 78.3 54.7 28.3 54.5 50.0 90.5 65.1 233.6 32.1 42.3 22.0 31.5 74.9 24.0 57.8 110.1 98.2 26.5 75.1 97.5 34.2 29.3 85.2 20.1 120.7 41.3 67.0 56.8 112.9 111.6 89.1 42.0 89.4 73.2 48.2 34.7 120.2 27.2 1.1 0.4 1.5 9.6 3.2 2.4 6.7 49.0 76.7 61.8 128.7 11.1 18.1 101.4 41.1 66.2 3.1 21.2 35.5 0.5 96.0 128.8 0.5 24.6 0.4 1.5 164.1 18.1 52.1 50.3 47.5 21.4 0.2 93.3 0.5 17.5 5.0 10.8 47.0 159.5 38.4 2.1 29.3 80.3 38.4 105.6 41.7 51.4 40.4 59.2 21.0 60.0 30.7 0.3 32.1 0.1 43.1 1.1 18.3 0.5 0.3 140.0 2.3 54.0 0.9 11.9 0.2 0.8 28.6 0.2 55.5 40.9 53.9 32.8 0.4 52.2 139.1 91.0 2.4 63.6 0.3 0.4 33.7 48.1 71.0 67.6 277.3 59.4 58.5 78.3 90.5 65.1 74.9 85.2 67.0 73.2 218.9 317.3 36.0 875.6 47.1 86.8 42.2 35.7 306.2 54.5 27.6 29.5 592.5 51.5 97.1 53.3 18.8 1.5 43.2 59.8 35.2 37.8 110.7 88.4 32.7 107.3 16.8 7.4 236.0 54.5 0.8 126.1 225.3 30.9 1.3 119.6 55.6 51.4 0.6 58.9 326.0 101.7 16.2 1.3 18.4 133.7 227.7 9.4 21.4 213.6 4.3 54.7 27.8 50.3 9.2 59.6 34.7 413.0 22.7 49.8 46.7 42.1 79.3 96.7 0.0 155.8 22.0 3.9 4.7 481.0 189.4 0.7 62.8 53.6 51.4 164.0 ACAA1 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 212.6;liver: 659.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.8;Hepatocytes: 686.0;Proximal enterocytes: 441.1;Proximal tubular cells: 721.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 224.0;SK-BR-3: 342.9" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" 42.8 54.1 47.5 24.0 54.4 44.7 41.2 54.3 49.5 28.3 42.3 56.9 101.0 20.8 44.6 56.7 19.4 29.8 84.8 44.6 48.7 212.6 659.3 34.9 26.1 54.2 50.4 20.9 59.3 47.9 24.8 17.2 53.0 55.1 51.2 4.9 38.9 25.3 48.2 30.7 89.5 18.7 50.9 41.3 42.1 15.5 53.6 28.0 32.1 53.8 30.0 43.7 33.5 54.9 35.5 39.8 13.0 40.7 55.6 32.2 44.6 32.2 47.0 36.3 34.5 52.8 38.8 21.1 22.6 52.0 17.4 24.5 34.9 54.0 20.0 31.0 37.2 27.0 35.4 155.5 35.3 63.3 59.8 59.0 39.3 31.2 22.5 23.9 49.9 49.7 26.2 24.2 41.3 49.2 60.3 45.3 13.3 224.0 47.0 13.9 25.0 34.3 103.4 110.4 10.9 16.5 31.7 342.9 23.7 18.0 35.1 48.9 36.8 21.9 21.1 43.2 44.2 31.9 21.7 16.1 34.8 54.4 34.7 79.9 114.4 130.4 48.8 159.1 41.2 33.9 45.7 47.4 178.1 36.0 45.2 42.5 76.3 71.9 187.7 104.5 77.2 82.1 47.5 54.4 54.3 49.5 44.6 48.7 54.2 50.4 53.0 50.9 53.6 54.9 30.7 41.7 38.7 50.6 45.6 33.3 56.5 57.6 40.9 36.9 48.7 37.1 3.2 98.7 44.3 66.2 14.6 91.6 61.7 356.8 166.3 98.0 4.5 40.7 38.6 25.4 55.1 40.4 25.6 78.4 64.5 34.4 76.5 39.1 19.0 32.5 37.1 686.0 81.7 8.4 24.7 73.1 48.8 93.5 86.8 9.6 35.8 83.2 58.7 14.0 89.5 43.1 53.5 12.5 30.9 100.9 270.6 33.1 44.5 60.6 441.1 721.8 26.3 16.7 32.9 28.5 27.4 19.8 11.7 48.1 35.5 99.3 44.4 186.7 84.3 87.0 ACACB "ACC2, ACCB, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116595-109268226 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 183.3;skeletal muscle: 173.2" "Cell type enhanced" "Detected in many" "Adipocytes: 128.7;Astrocytes: 136.8;Hepatocytes: 216.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 17.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.5" "Cell line enriched" "Detected in many" 18 "ASC diff: 222.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA006554 Enhanced "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA006554: AB_1844495" "unprognostic (2.24e-1)" "unprognostic (4.66e-1)" "unprognostic (3.97e-2)" "unprognostic (4.54e-6)" "unprognostic (2.82e-1)" "unprognostic (1.59e-2)" "unprognostic (8.62e-3)" "unprognostic (5.81e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.63e-2)" "prognostic favorable (1.15e-5)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-3)" "unprognostic (2.58e-2)" 183.3 19.8 19.6 3.3 21.7 3.6 100.5 7.6 11.4 12.9 26.9 37.2 8.4 12.0 3.5 10.6 12.1 10.9 35.4 10.1 11.2 12.6 54.3 6.7 3.8 12.7 19.4 14.3 19.2 17.9 11.2 2.5 11.6 11.8 8.2 1.7 12.5 11.7 173.2 9.5 15.5 9.4 6.7 7.8 18.6 4.9 19.1 4.5 18.1 61.5 3.0 23.0 11.5 13.2 0.9 5.7 3.6 6.9 222.6 1.7 2.6 0.9 1.5 1.0 0.6 4.1 1.1 2.9 1.6 1.2 2.4 4.8 3.0 1.5 0.6 3.8 5.3 6.6 6.2 4.3 1.0 5.7 1.6 2.6 1.5 2.3 0.6 1.7 0.5 4.9 0.7 0.3 0.7 1.7 4.1 5.3 3.9 0.4 12.4 2.2 4.8 1.5 1.8 2.0 2.3 5.4 5.9 2.8 3.4 1.5 2.6 5.9 0.4 2.2 1.3 2.5 1.9 8.8 5.3 4.0 5.3 4.5 1.7 4.6 0.4 17.5 1.1 0.1 0.6 2.2 1.0 0.3 0.2 3.0 1.8 0.9 0.7 0.1 0.2 0.3 0.6 0.1 19.6 21.7 7.6 11.4 10.1 11.2 12.7 19.4 11.6 6.7 19.1 13.2 128.7 6.4 1.1 136.8 3.7 2.3 2.6 1.0 3.4 3.1 32.5 5.0 35.3 25.8 1.7 23.9 0.0 0.6 2.4 13.9 1.9 2.1 34.3 3.3 3.4 26.0 10.2 25.7 5.1 4.0 0.5 16.0 18.3 1.3 1.3 20.0 41.4 216.5 1.7 23.5 6.4 9.6 0.0 12.6 2.4 36.4 29.2 3.7 5.4 28.1 1.2 5.2 2.1 29.7 25.8 2.7 7.3 50.4 2.5 0.9 17.9 6.5 2.3 4.1 6.6 29.3 12.0 2.3 3.0 2.5 1.6 0.1 3.5 21.8 11.8 1.1 ACAD10 MGC5601 ENSG00000111271 "Acyl-CoA dehydrogenase family member 10" Q6JQN1 12 111686053-111757107 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067222 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" "HPA067222: AB_2685805" "unprognostic (8.45e-2)" "unprognostic (1.36e-2)" "unprognostic (1.12e-1)" "unprognostic (2.15e-3)" "unprognostic (6.01e-2)" "unprognostic (5.74e-2)" "unprognostic (1.38e-1)" "unprognostic (1.38e-2)" "unprognostic (1.56e-2)" "unprognostic (1.68e-2)" "unprognostic (6.21e-3)" "unprognostic (6.21e-2)" "prognostic favorable (3.71e-6)" "unprognostic (2.37e-2)" "unprognostic (5.81e-2)" "unprognostic (6.45e-2)" "unprognostic (4.87e-2)" 7.5 14.7 4.1 6.6 5.6 9.1 8.2 6.7 5.5 8.2 11.4 13.4 16.0 7.6 10.8 9.0 9.8 7.9 15.1 5.0 4.5 19.3 22.7 6.3 8.7 5.2 4.7 10.3 13.4 18.7 12.1 7.5 5.7 9.7 11.1 9.1 10.6 8.0 13.0 11.9 14.8 7.8 3.7 9.3 12.5 7.7 5.3 10.0 12.9 9.0 8.6 8.5 8.3 8.6 6.8 18.7 7.9 10.3 12.2 15.9 14.2 6.0 9.5 6.5 5.0 6.9 11.2 5.0 6.3 7.0 6.1 15.8 7.4 6.4 3.4 11.8 10.4 8.0 13.7 9.1 12.4 6.7 10.0 18.3 11.5 9.4 9.3 13.7 7.3 11.6 5.6 10.1 5.9 9.5 8.1 10.6 12.4 9.7 12.7 8.7 4.0 14.3 12.6 15.1 7.5 12.0 7.0 12.5 19.1 10.6 28.7 13.0 4.5 5.9 4.5 9.3 5.8 12.8 6.4 8.6 8.8 9.4 9.2 6.9 6.2 3.6 3.6 6.9 3.9 4.0 3.6 3.6 6.1 3.3 3.5 3.5 6.7 4.8 8.6 3.5 5.0 3.6 4.1 5.6 6.7 5.5 5.0 4.5 5.2 4.7 5.7 3.7 5.3 8.6 3.7 6.4 11.6 19.6 7.2 1.9 3.4 5.6 5.7 11.7 5.5 5.5 17.1 7.2 5.7 3.7 25.0 9.4 5.2 9.3 0.0 5.0 12.2 5.7 5.6 5.1 11.4 1.3 11.8 4.7 5.2 4.1 14.3 5.1 2.5 15.0 5.0 14.8 5.7 10.1 14.7 10.6 4.1 6.7 2.3 8.7 5.9 5.8 1.8 9.4 8.0 7.0 3.1 14.1 22.9 3.7 7.8 3.0 5.4 3.4 17.1 12.1 6.1 23.7 0.0 5.5 5.5 11.3 11.7 4.5 2.8 5.6 4.8 10.2 12.9 2.1 ACAD8 ENSG00000151498 "Acyl-CoA dehydrogenase family member 8" Q9UKU7 11 134253548-134265855 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism, Transcription, Transcription regulation" "Activator, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040689, HPA043903" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA040689: AB_2677080, HPA043903: AB_2678724" "unprognostic (5.00e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.62e-4)" "unprognostic (7.57e-3)" "unprognostic (9.83e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.53e-1)" "prognostic favorable (2.38e-4)" "unprognostic (4.10e-2)" "unprognostic (2.84e-1)" "unprognostic (7.81e-3)" "unprognostic (2.16e-1)" "prognostic favorable (6.42e-10)" "unprognostic (1.08e-1)" "unprognostic (1.17e-2)" "unprognostic (4.02e-2)" "unprognostic (1.03e-2)" 11.0 18.1 13.9 3.5 14.2 6.8 11.3 14.3 15.4 7.5 18.7 11.6 11.3 6.3 12.6 9.6 9.4 5.2 27.2 14.7 14.3 31.6 24.8 7.8 5.0 14.3 14.1 6.9 16.7 12.4 6.5 4.8 13.8 20.5 10.9 5.0 12.6 7.5 32.5 14.3 8.4 8.3 14.5 8.6 12.6 6.3 14.8 8.5 27.7 39.2 8.9 8.4 6.9 14.8 5.9 5.9 11.8 17.6 20.2 11.5 13.5 11.3 14.0 14.7 10.3 16.2 10.8 14.2 21.1 11.7 15.5 6.0 14.6 14.3 10.2 13.0 4.7 29.4 5.8 11.3 17.0 16.5 18.3 13.8 4.4 14.8 4.5 13.3 16.3 20.8 13.8 7.0 12.4 7.5 12.2 18.1 17.0 49.8 9.7 9.8 11.9 8.5 20.1 17.5 3.7 11.7 19.5 14.8 7.3 11.9 31.0 15.0 11.3 7.1 7.5 6.2 11.2 7.8 3.8 12.7 7.2 15.4 11.2 36.2 13.4 23.1 11.8 13.5 11.5 11.6 11.1 11.7 12.7 9.2 13.0 11.7 12.1 31.5 12.9 10.8 15.1 12.3 13.9 14.2 14.3 15.4 14.7 14.3 14.3 14.1 13.8 14.5 14.8 14.8 11.7 3.2 12.2 15.3 8.8 6.0 4.7 23.5 7.4 11.2 17.5 11.9 24.6 4.3 19.7 18.4 14.6 19.7 14.0 20.0 52.8 12.1 5.3 8.2 11.8 9.7 3.6 12.0 21.5 11.9 10.6 9.8 10.2 8.5 3.8 15.7 10.8 36.7 12.9 15.2 16.0 14.3 48.8 14.2 6.9 6.1 11.5 10.0 28.4 13.1 12.7 11.8 9.2 12.1 15.8 12.6 15.8 10.1 14.6 5.9 17.4 59.8 20.1 17.1 6.6 8.7 9.6 22.4 17.3 10.9 7.7 8.3 10.5 36.0 14.9 5.3 ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 289.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" 81.9 82.2 25.2 24.3 25.0 17.3 69.9 26.6 42.2 29.3 30.4 46.8 103.9 20.0 25.3 51.3 30.6 27.8 217.8 24.3 25.9 295.9 367.3 22.6 42.6 26.9 26.8 35.7 35.9 66.3 19.2 16.9 25.8 26.8 49.5 21.2 31.4 26.2 380.0 14.4 75.6 25.5 26.2 27.4 52.8 35.7 25.8 29.7 38.4 475.9 44.3 32.7 21.3 25.2 25.8 20.5 61.0 26.8 53.1 42.1 17.5 48.1 40.4 46.1 38.5 38.3 39.5 289.1 40.7 34.4 39.0 22.8 54.9 41.8 57.8 113.0 25.5 94.4 58.5 58.3 36.4 80.0 23.9 50.7 23.5 39.8 22.8 35.0 36.2 56.6 102.3 60.4 50.5 9.6 96.3 40.6 50.2 80.4 49.5 118.8 83.8 30.6 77.9 70.7 33.8 43.0 38.0 111.6 102.0 43.1 32.7 107.6 20.2 29.9 29.6 26.6 78.1 38.6 62.0 128.1 25.8 67.0 35.3 15.3 14.2 19.3 17.1 20.9 27.3 40.7 17.8 21.5 21.4 24.6 20.3 23.6 0.5 25.0 20.4 23.2 19.5 19.5 25.2 25.0 26.6 42.2 24.3 25.9 26.9 26.8 25.8 26.2 25.8 25.2 42.9 57.7 58.3 29.7 56.5 27.3 41.8 69.0 44.3 39.0 49.0 40.9 373.1 52.9 63.0 58.8 25.0 35.8 39.4 42.6 344.4 37.9 55.4 27.1 32.2 36.2 40.7 67.6 51.6 26.5 19.5 47.6 26.0 25.4 44.9 61.5 43.9 261.2 75.7 30.3 46.7 38.7 63.1 45.6 22.2 24.4 46.9 38.2 51.6 19.7 32.8 53.7 29.9 36.2 36.0 21.2 49.7 45.5 74.9 24.2 88.0 564.8 106.7 30.0 0.0 38.6 43.7 76.3 86.1 46.6 27.0 15.3 39.4 72.5 46.7 35.9 ACADSB "ACAD7, SBCAD" ENSG00000196177 "Acyl-CoA dehydrogenase short/branched chain" P45954 10 123008979-123058290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 360.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 499.5;Proximal tubular cells: 137.9" "Cancer enhanced" "Detected in all" "liver cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041458, HPA063555" Enhanced Supported Mitochondria NA NA 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA041458: AB_2677491, HPA063555: " "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.91e-3)" "unprognostic (2.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-3)" "unprognostic (1.30e-1)" "unprognostic (3.67e-1)" "prognostic favorable (3.40e-4)" "unprognostic (9.37e-3)" "prognostic favorable (6.37e-12)" "unprognostic (2.69e-1)" "unprognostic (7.20e-2)" "unprognostic (1.60e-3)" "unprognostic (7.14e-2)" 14.8 27.4 8.0 7.1 8.5 3.8 23.9 13.9 10.3 7.8 13.1 15.9 52.4 9.9 7.7 12.6 9.7 7.6 38.5 8.6 6.7 90.2 360.1 12.7 8.2 6.3 7.6 12.8 15.8 33.4 8.8 5.1 6.8 22.7 16.8 12.4 15.7 11.2 42.4 9.8 11.0 8.5 5.9 6.4 14.0 8.4 8.0 7.4 12.3 69.1 10.3 10.8 8.1 8.4 15.4 10.9 7.9 14.5 10.6 13.1 7.0 9.3 18.8 9.2 9.1 9.6 4.9 16.0 6.3 7.9 5.6 6.3 12.5 6.5 15.1 10.6 12.9 8.3 3.3 54.8 7.5 12.0 7.6 9.7 6.5 5.8 5.3 13.5 9.0 13.2 8.1 11.5 11.5 7.1 11.4 9.8 4.8 8.5 6.7 13.4 16.6 5.1 13.1 16.9 1.4 9.1 14.3 4.2 14.4 7.5 12.9 5.8 9.5 4.9 4.4 11.4 11.4 12.9 15.5 8.5 7.6 11.1 3.8 17.4 4.5 11.8 8.8 4.7 10.2 5.5 8.1 7.6 6.4 5.7 7.4 8.3 2.9 8.5 2.9 3.8 7.1 5.7 8.0 8.5 13.9 10.3 8.6 6.7 6.3 7.6 6.8 5.9 8.0 8.4 7.7 28.9 53.1 29.4 11.6 9.3 9.2 8.2 14.2 17.4 58.6 27.8 80.7 37.1 21.1 11.0 10.4 20.1 8.7 11.2 46.9 7.3 7.0 6.8 9.1 8.2 12.1 21.4 39.8 4.8 3.5 10.6 10.7 18.8 3.8 29.1 15.4 499.5 7.3 21.9 49.6 13.7 26.4 17.4 5.9 8.1 13.4 7.1 7.2 12.2 7.9 12.0 7.2 15.6 38.3 4.6 13.1 10.9 9.1 19.8 9.2 137.9 15.2 7.7 19.7 12.3 11.0 8.5 3.7 14.7 13.8 30.1 13.3 18.9 18.3 12.0 ACADVL "ACAD6, LCACD, VLCAD" ENSG00000072778 "Acyl-CoA dehydrogenase very long chain" P49748 17 7217125-7225266 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 850.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019006, HPA020595" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria NA NA 98000 "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Nucleoplasm, Nucleoli" "HPA019006: AB_1844478, HPA020595: AB_1844479" "unprognostic (4.81e-2)" "unprognostic (2.86e-1)" "unprognostic (2.21e-2)" "unprognostic (1.09e-2)" "unprognostic (6.63e-3)" "unprognostic (1.51e-1)" "unprognostic (1.89e-2)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (6.87e-4)" "unprognostic (3.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-1)" "unprognostic (4.01e-1)" "unprognostic (2.84e-3)" 197.9 405.2 120.1 78.7 131.0 103.5 142.9 128.4 126.7 110.5 170.6 157.3 306.2 98.5 44.4 181.0 94.0 92.6 576.8 117.8 125.0 215.3 517.4 106.7 52.0 127.5 125.3 80.9 236.5 159.6 189.6 112.0 124.8 133.2 131.6 34.9 158.5 113.9 850.4 135.7 270.6 110.6 118.2 132.2 186.4 75.9 132.0 83.4 159.3 817.1 82.9 137.1 115.3 122.7 193.7 162.5 65.8 92.4 271.2 99.2 135.9 156.5 169.0 136.9 84.5 67.2 155.3 90.4 109.0 260.0 49.7 147.9 43.8 135.5 119.6 295.9 47.1 50.6 120.9 101.1 131.2 49.0 129.5 112.5 122.0 114.7 178.5 212.6 124.8 111.3 73.3 110.2 222.7 65.3 49.6 68.4 34.3 178.4 91.9 70.4 78.3 227.2 305.1 155.0 19.1 47.3 206.8 224.8 110.8 60.6 102.8 74.9 151.5 127.5 101.6 75.9 149.9 104.5 59.1 5.2 230.7 85.7 94.9 24.2 96.1 121.3 39.1 57.8 35.7 25.2 32.5 43.8 99.9 24.6 23.7 29.1 20.2 37.8 39.3 80.4 31.8 79.4 120.1 131.0 128.4 126.7 117.8 125.0 127.5 125.3 124.8 118.2 132.0 122.7 109.9 60.9 81.9 143.3 72.3 87.3 336.0 322.4 91.6 42.0 157.7 104.5 451.4 138.7 206.7 202.3 62.6 482.9 87.7 484.2 185.9 310.8 133.0 87.2 52.7 77.4 179.3 65.2 40.9 77.0 197.8 118.6 406.7 88.5 88.4 121.1 53.6 365.4 182.4 33.7 33.4 251.8 233.9 67.9 94.6 249.9 124.5 101.5 81.8 34.7 274.9 40.7 73.2 23.1 24.5 106.1 388.9 132.8 172.3 369.0 489.8 345.8 144.1 41.3 105.2 88.3 147.4 114.3 47.8 113.8 87.5 663.3 75.5 169.2 316.8 367.5 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 374.2;Proximal tubular cells: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 88.8 81.6 154.2 38.6 152.2 32.0 52.4 153.0 190.0 39.5 160.1 94.4 162.9 42.0 26.1 60.4 53.6 36.5 567.7 155.2 153.1 138.9 73.9 40.7 40.5 146.1 145.3 30.8 53.8 233.8 33.6 30.5 147.8 41.2 69.6 46.9 72.0 49.5 660.4 45.5 158.5 43.7 152.5 44.7 110.2 35.1 186.3 38.0 53.7 695.8 43.3 52.5 42.4 159.6 47.2 55.8 56.5 116.3 101.2 69.8 78.7 43.7 60.9 79.0 71.9 81.2 63.5 115.7 72.2 70.6 60.3 109.8 108.8 88.3 42.8 75.8 80.2 51.0 73.7 95.0 86.7 147.8 77.8 120.8 64.4 78.9 83.2 61.7 81.2 61.5 72.9 118.4 65.4 91.7 73.7 47.9 37.0 282.6 115.1 102.3 37.8 162.1 106.8 97.3 37.8 33.9 112.2 128.7 82.0 44.9 74.9 74.7 55.5 60.0 68.7 50.2 45.0 64.7 92.1 80.6 102.0 64.0 66.5 10.3 52.9 18.1 32.0 76.4 29.3 49.4 25.5 34.9 69.0 46.4 29.2 30.8 9.0 39.4 97.1 24.0 41.2 58.6 154.2 152.2 153.0 190.0 155.2 153.1 146.1 145.3 147.8 152.5 186.3 159.6 26.3 25.6 31.8 45.4 49.4 18.7 54.5 102.7 31.3 60.6 28.0 23.2 9.1 64.3 63.5 60.7 81.3 100.3 33.3 190.8 131.0 58.3 14.5 37.2 17.7 26.1 53.2 30.3 28.8 42.6 60.0 24.0 77.5 37.1 40.6 56.7 20.7 64.6 91.5 53.8 34.0 99.1 89.5 35.5 26.4 8.9 24.2 39.2 35.6 7.5 68.3 73.9 34.0 12.1 20.9 43.9 103.5 27.8 63.2 34.4 374.2 285.7 59.2 73.5 59.2 28.6 38.4 26.4 38.2 35.8 16.1 193.2 30.7 54.4 113.6 64.9 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT13 "HT012, THEM2" ENSG00000112304 "Acyl-CoA thioesterase 13" Q9NPJ3 6 24667035-24705065 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.6" "Cell type enhanced" "Detected in all" "Early spermatids: 847.1;Proximal tubular cells: 525.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019881, HPA057134" Enhanced Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" "Cell Junctions" "HPA019881: AB_1857978, HPA057134: " "unprognostic (3.61e-1)" "unprognostic (1.62e-1)" "unprognostic (6.02e-2)" "unprognostic (1.80e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "prognostic favorable (2.53e-6)" "unprognostic (3.67e-2)" "unprognostic (1.64e-2)" "unprognostic (7.16e-2)" "unprognostic (5.97e-2)" "unprognostic (4.86e-2)" "unprognostic (1.50e-1)" "unprognostic (2.13e-2)" 6.3 6.1 7.2 4.8 7.5 3.4 3.8 7.9 7.3 3.4 6.0 9.1 6.5 3.1 3.7 3.4 3.6 4.9 12.0 6.6 7.8 19.2 30.6 4.6 5.2 7.2 7.8 3.9 6.6 7.2 5.1 3.0 7.4 6.5 7.4 9.6 5.0 3.3 12.2 5.5 6.1 3.1 7.1 4.8 5.5 7.0 8.2 5.1 5.7 10.3 3.4 3.5 3.1 7.4 5.9 7.6 7.6 13.6 10.5 13.1 4.2 4.8 5.8 3.5 5.4 10.1 7.5 11.1 16.2 5.5 18.4 6.4 6.7 9.7 5.4 17.4 6.2 10.4 7.7 7.0 5.3 6.7 4.6 7.6 9.4 4.7 9.0 8.5 8.3 11.3 17.0 5.7 7.0 6.1 12.1 12.9 5.1 11.7 5.9 10.4 6.6 14.0 11.7 5.4 15.0 5.2 5.7 19.1 14.1 8.8 13.2 5.5 9.7 6.2 3.5 1.7 4.6 10.7 29.3 11.1 6.5 23.8 19.1 4.8 5.3 3.6 4.4 5.7 6.1 6.9 4.9 5.0 4.7 4.9 5.7 5.1 6.2 4.6 5.8 3.7 5.3 4.8 7.2 7.5 7.9 7.3 6.6 7.8 7.2 7.8 7.4 7.1 8.2 7.4 27.9 67.3 41.7 19.6 19.7 17.2 26.6 66.4 18.8 18.7 29.4 32.3 94.6 45.8 46.9 31.3 16.7 56.8 22.6 88.4 158.5 43.2 847.1 34.0 31.3 24.0 54.7 37.2 12.1 40.2 31.1 26.2 23.9 31.8 14.5 30.3 21.4 215.5 86.7 5.0 14.3 85.8 67.1 24.5 23.7 131.5 19.6 35.0 26.6 14.0 68.9 41.7 18.6 15.6 18.7 29.2 130.7 24.0 25.4 23.2 47.1 525.2 56.8 31.8 26.3 50.6 64.2 117.1 27.3 19.5 23.4 40.0 20.5 43.4 69.4 28.6 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 8.8 8.3 4.1 2.1 4.6 0.1 5.8 4.4 4.5 9.3 16.8 12.9 25.4 9.4 5.8 6.3 10.8 8.2 16.7 4.3 4.5 42.1 177.3 6.2 1.7 5.3 4.8 11.2 4.6 9.6 4.6 3.4 4.4 10.8 8.3 1.8 7.2 9.8 8.2 2.9 21.6 11.2 4.5 1.4 4.0 4.9 4.9 4.0 16.1 17.0 1.2 8.7 6.0 4.1 0.0 0.0 0.2 0.0 16.4 25.9 4.7 3.1 0.2 0.0 0.4 0.8 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.6 4.4 4.5 4.3 4.5 5.3 4.8 4.4 4.5 4.9 4.1 1.9 3.2 5.8 11.1 0.6 0.6 7.6 0.5 5.7 0.3 1.3 3.8 14.3 4.3 0.9 3.7 0.0 0.7 0.0 4.2 15.6 0.3 0.1 0.4 1.3 1.6 3.0 2.7 0.6 1.9 0.4 8.6 2.0 0.2 1.3 8.6 6.1 89.0 5.2 1.7 0.6 5.1 0.0 1.9 0.4 1.8 10.8 1.7 0.0 1.0 0.5 10.8 0.0 0.5 0.0 0.4 0.8 8.6 0.1 0.6 27.9 51.0 0.0 0.8 6.6 7.0 5.2 0.4 0.4 3.0 0.3 0.8 0.3 9.6 4.6 3.8 ACP6 "ACPL1, LPAP" ENSG00000162836 "Acid phosphatase 6, lysophosphatidic" Q9NPH0 1 147629652-147670524 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 108.9;RPTEC TERT1: 119.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028560 Uncertain "Intracellular and membrane" NA NA 64000 "Cluster 35: T-regs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA028560: AB_10602427" "unprognostic (3.17e-2)" "unprognostic (3.01e-2)" "unprognostic (3.50e-1)" "unprognostic (1.87e-2)" "unprognostic (3.85e-1)" "unprognostic (8.50e-3)" "unprognostic (3.36e-3)" "unprognostic (1.00e-1)" "unprognostic (6.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (3.94e-1)" "unprognostic (8.07e-2)" "unprognostic (1.26e-1)" "prognostic favorable (6.44e-4)" 6.3 13.6 6.2 4.2 6.3 5.0 17.8 5.6 6.6 11.8 7.9 11.4 7.4 8.3 16.2 7.8 12.7 6.8 8.4 5.9 6.3 17.5 13.2 7.3 3.9 6.3 6.9 9.3 11.0 21.9 15.2 4.2 6.2 12.6 9.7 3.6 10.4 11.2 6.7 9.3 8.8 6.0 6.0 6.0 12.4 5.7 6.1 7.9 15.2 6.0 6.9 11.2 6.7 5.7 21.1 8.5 7.1 12.7 4.5 4.3 20.2 4.8 14.8 14.8 17.5 10.2 31.9 6.1 17.4 10.4 11.4 35.6 9.6 32.0 15.4 8.2 16.1 21.9 11.8 19.4 13.2 3.9 0.8 6.3 23.3 7.7 15.4 17.6 15.2 30.2 10.5 3.4 17.0 15.8 16.5 10.0 17.0 108.9 62.9 11.7 6.1 70.9 119.7 41.3 5.8 7.1 17.5 12.5 36.5 15.9 20.3 6.0 10.7 4.6 8.6 0.9 15.1 13.4 21.3 2.8 8.7 0.3 25.8 0.1 2.3 13.4 4.6 0.8 7.9 2.6 7.5 6.1 5.4 2.8 8.2 7.0 3.5 0.3 0.3 3.4 14.8 2.7 6.2 6.3 5.6 6.6 5.9 6.3 6.3 6.9 6.2 6.0 6.1 5.7 2.1 19.2 13.9 74.4 2.9 1.1 6.1 7.4 7.4 3.1 6.3 6.3 7.0 10.0 6.7 16.5 0.0 19.7 7.0 3.7 17.6 7.5 6.0 9.1 2.3 2.4 9.1 4.2 14.2 15.3 7.2 2.4 10.7 9.4 1.3 15.2 5.3 10.9 4.6 0.0 20.6 8.5 8.2 4.8 6.7 1.5 5.9 2.9 3.6 15.0 3.4 8.8 4.1 18.1 10.4 18.7 5.4 4.1 3.8 4.9 6.3 14.4 11.9 1.1 13.1 5.7 7.7 7.5 4.7 9.1 1.3 8.1 9.6 7.3 8.5 5.8 ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.6;brain: 32.0;retina: 45.8;testis: 20.7" "Cell type enhanced" "Detected in many" "Astrocytes: 229.2;Cone photoreceptor cells: 229.4;Erythroid cells: 110.5;Inhibitory neurons: 110.6;Rod photoreceptor cells: 130.0" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Group enriched" "Detected in some" 5 "SCLC-21H: 7.6;U-937: 6.2" HPA040470 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" 0.2 4.2 14.8 1.4 18.3 22.6 0.2 26.3 32.0 0.1 1.2 0.5 4.7 0.1 0.5 0.3 0.2 0.3 1.4 18.6 12.8 1.9 2.0 0.3 2.4 22.2 18.2 0.0 1.1 11.3 4.2 0.6 18.9 0.3 0.3 45.8 0.3 18.0 2.3 0.1 2.4 0.1 13.8 1.1 0.6 20.7 25.0 0.6 0.4 1.4 1.0 0.2 0.1 14.3 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.1 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.2 6.2 0.3 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.7 1.6 0.0 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 0.3 14.8 18.3 26.3 32.0 18.6 12.8 22.2 18.2 18.9 13.8 25.0 14.3 0.6 25.6 29.2 229.2 1.4 1.9 1.5 0.0 2.2 65.2 2.1 0.4 0.0 1.5 16.1 1.8 229.4 0.3 3.3 0.6 7.9 0.6 43.7 0.3 0.1 3.9 2.4 110.5 70.6 0.2 0.1 4.2 0.0 0.2 10.1 0.2 1.8 8.4 0.1 21.9 110.6 1.8 0.0 1.0 15.9 7.9 0.3 6.4 0.0 15.9 0.9 24.5 0.0 41.7 9.8 0.3 1.6 1.9 0.8 1.1 1.8 0.4 8.1 130.0 0.0 2.3 1.1 45.3 1.7 0.1 1.3 0.3 15.3 0.1 0.4 1.3 ACTN2 ENSG00000077522 "Actinin alpha 2" P35609 1 236664141-236764631 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 53 "heart muscle: 772.7;skeletal muscle: 2134.7;tongue: 1262.2" "Cell type enriched" "Detected in some" 11 "Cardiomyocytes: 1762.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 2.0;HEK 293: 1.3;HSkMC: 5.9;hTEC/SVTERT24-B: 2.7" "Region enhanced" "Detected in many" "basal ganglia: 66.6" "Region enhanced" "Detected in all" "basal ganglia: 44.5" "HPA006035, HPA008315" Enhanced Uncertain "Actin filaments" NA NA 25000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Actin filaments" "HPA006035: AB_1078095, HPA008315: AB_1844543" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (2.41e-2)" "unprognostic (1.69e-3)" "unprognostic (2.91e-1)" "unprognostic (4.32e-3)" "unprognostic (7.85e-2)" "unprognostic (2.97e-3)" "unprognostic (2.17e-2)" "unprognostic (2.80e-1)" "unprognostic (2.97e-1)" "unprognostic (2.66e-1)" "unprognostic (2.71e-11)" "unprognostic (1.30e-2)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" 0.7 0.2 12.0 0.0 26.3 0.1 0.9 8.0 20.1 0.3 11.0 0.4 0.0 0.5 0.0 21.8 0.5 0.7 772.7 13.2 12.1 0.5 0.3 3.9 0.2 9.7 8.1 1.1 1.6 0.1 0.5 0.1 10.7 16.1 0.0 1.3 18.4 0.1 2134.7 1.3 0.5 1.8 8.0 0.2 3.8 4.2 8.7 0.5 0.7 1262.2 0.1 3.5 0.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 1.0 2.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.0 0.0 0.2 5.9 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 26.3 8.0 20.1 13.2 12.1 9.7 8.1 10.7 8.0 8.7 14.2 0.3 0.0 0.6 18.6 0.0 0.3 0.4 0.0 1.2 2.6 0.4 0.5 1762.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 8.6 0.5 1.2 10.4 0.0 0.0 40.9 0.7 0.0 43.7 3.6 1.4 0.0 0.1 1.8 0.2 0.1 0.0 11.3 0.0 0.0 0.0 0.3 24.6 0.6 1.2 0.0 11.2 0.0 0.0 0.0 24.6 156.9 0.2 0.0 0.4 0.0 0.2 0.0 1.4 0.0 1.2 0.0 66.3 12.4 3.1 2.0 1.2 0.1 0.0 0.4 0.4 0.0 0.2 ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.4;tongue: 163.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 162.6;Excitatory neurons: 158.8;Oligodendrocytes: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA035301: AB_10670291" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (6.90e-3)" "unprognostic (6.21e-2)" "unprognostic (2.03e-3)" "unprognostic (3.17e-1)" "unprognostic (5.22e-2)" "unprognostic (7.83e-3)" "unprognostic (3.64e-3)" "unprognostic (1.16e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (2.24e-2)" 19.5 42.8 64.9 5.4 72.9 7.1 15.7 74.8 85.4 10.6 61.5 14.3 7.4 11.5 12.8 10.4 11.6 8.5 63.4 63.9 72.8 14.5 28.0 10.6 10.9 69.5 68.8 9.3 12.7 13.6 26.2 6.5 70.3 14.4 5.3 24.1 15.2 9.2 207.4 9.9 9.0 7.9 70.4 12.7 12.9 10.2 70.4 10.7 12.6 163.2 8.4 14.0 10.7 76.9 11.7 5.9 6.0 4.4 23.7 17.3 3.7 11.5 9.7 8.3 7.3 1.5 7.1 21.5 33.0 12.6 7.8 8.5 3.3 10.8 7.4 14.4 13.1 13.4 6.3 16.3 8.5 12.7 6.3 13.6 19.3 5.6 9.5 15.2 3.9 9.8 5.5 11.5 17.9 7.6 7.5 17.0 5.9 8.4 6.7 5.4 4.7 12.2 18.8 10.6 17.6 10.0 17.4 10.0 5.7 1.9 3.4 13.2 10.9 11.5 10.6 3.5 11.1 21.4 12.5 10.2 16.3 24.3 12.4 41.2 14.0 26.1 16.9 13.0 15.4 29.0 16.6 16.1 20.3 26.9 20.1 16.4 11.5 18.6 13.5 33.4 16.3 11.3 64.9 72.9 74.8 85.4 63.9 72.8 69.5 68.8 70.3 70.4 70.4 76.9 21.7 16.0 17.9 84.9 30.6 20.5 41.9 52.8 18.8 15.5 49.7 65.7 162.6 34.3 32.0 18.4 10.4 13.6 27.9 24.5 62.6 24.3 86.8 29.5 23.6 23.1 30.6 14.5 158.8 38.1 6.1 21.0 26.0 19.5 19.7 17.6 30.7 74.2 31.9 28.6 134.1 21.9 36.7 40.0 28.5 64.7 13.4 25.4 23.2 59.0 26.1 90.1 24.7 67.8 180.1 29.9 18.8 30.9 36.4 27.4 29.1 55.6 32.2 31.6 52.6 30.8 30.0 22.9 9.8 28.9 21.3 10.3 22.7 29.7 18.6 45.0 ADAL ENSG00000168803 "Adenosine deaminase like" Q6DHV7 15 43330672-43354569 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 81.3;Rod photoreceptor cells: 84.8;Spermatocytes: 99.5;Spermatogonia: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039879, HPA048175, HPA058795" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear speckles, Vesicles" "HPA039879: , HPA048175: AB_2680298, HPA058795: " "unprognostic (1.65e-2)" "unprognostic (1.53e-3)" "unprognostic (9.80e-2)" "unprognostic (3.15e-3)" "unprognostic (2.46e-3)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "unprognostic (5.83e-2)" "unprognostic (5.90e-2)" "unprognostic (2.68e-1)" "unprognostic (6.85e-3)" "unprognostic (1.69e-1)" "prognostic favorable (7.64e-9)" "unprognostic (2.37e-3)" "unprognostic (8.77e-2)" "unprognostic (5.31e-2)" "unprognostic (2.44e-2)" 6.2 6.6 6.7 4.2 7.1 4.4 5.9 7.6 9.6 3.6 10.2 5.7 5.8 4.3 8.4 4.1 3.3 3.8 20.9 6.3 7.4 11.9 8.2 3.5 4.8 6.7 7.2 3.6 3.6 10.4 6.1 2.7 7.0 6.2 4.8 21.2 4.2 6.4 20.4 2.6 4.6 4.7 6.9 3.8 4.0 11.1 7.1 5.4 10.9 23.4 4.8 4.6 3.0 7.4 6.8 3.4 13.3 15.1 5.5 7.1 6.3 8.1 8.2 12.6 19.3 14.2 3.5 8.0 13.0 8.9 16.7 7.5 0.0 5.7 10.8 8.5 8.0 19.0 23.1 12.0 6.9 0.0 14.8 9.1 10.3 8.5 8.7 8.1 2.7 19.4 21.1 16.2 13.2 4.6 12.3 9.7 5.5 7.8 4.6 15.9 19.9 12.7 11.0 4.1 16.3 11.6 13.1 11.7 12.4 7.2 12.5 12.5 3.7 21.9 10.6 16.6 16.5 16.6 29.9 3.4 12.2 21.2 18.1 5.9 1.4 3.8 2.4 2.0 1.8 2.0 2.2 1.9 2.0 1.6 2.3 2.9 1.1 2.3 1.9 2.9 4.5 1.3 6.7 7.1 7.6 9.6 6.3 7.4 6.7 7.2 7.0 6.9 7.1 7.4 5.9 9.6 10.3 32.7 10.0 7.0 7.4 9.3 7.4 40.7 9.2 9.9 51.2 10.0 6.9 18.4 81.3 7.1 13.3 7.0 58.7 8.9 17.6 10.6 10.3 8.2 7.7 19.1 24.4 8.5 7.0 10.4 5.1 6.8 7.6 15.7 11.0 30.8 8.9 42.1 26.7 7.2 10.2 8.8 7.0 12.7 9.6 8.9 8.8 10.3 5.4 35.5 24.7 19.1 18.3 5.7 1.3 8.6 6.9 7.1 13.0 29.0 10.9 84.8 6.6 11.6 7.3 99.5 82.5 8.8 4.4 2.6 7.0 12.6 11.6 4.4 ADAM23 MDC3 ENSG00000114948 "ADAM metallopeptidase domain 23" O75077 2 206443532-206621127 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.7;parathyroid gland: 82.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 410.0;Inhibitory neurons: 236.6;Oligodendrocyte precursor cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "memory CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 16 "T-cells: 2.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 54.4;RH-30: 63.8;RPMI-8226: 172.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033276 Approved "Secreted in brain" NA NA 890000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB033276: AB_2305247" "unprognostic (7.33e-2)" "unprognostic (7.80e-2)" "unprognostic (4.60e-1)" "unprognostic (5.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.59e-2)" "unprognostic (4.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (6.84e-2)" "unprognostic (1.09e-2)" "unprognostic (2.64e-2)" "unprognostic (9.75e-6)" "unprognostic (3.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-3)" "unprognostic (1.03e-3)" 1.7 7.5 14.3 2.4 20.6 2.0 1.1 3.5 45.7 3.2 0.0 3.0 1.5 2.2 3.8 4.0 0.8 4.2 30.7 20.6 9.6 0.9 0.3 1.5 2.1 13.9 10.2 2.0 1.2 82.9 6.4 0.2 12.9 1.7 2.2 17.4 1.5 2.4 11.1 1.1 3.2 4.5 1.6 0.8 1.6 8.0 17.4 4.9 1.0 8.7 2.7 3.0 4.1 24.0 0.1 0.9 22.3 0.0 11.9 17.2 0.9 2.4 2.9 3.2 0.6 26.8 0.5 3.3 0.0 3.8 39.5 33.9 14.5 0.7 0.3 13.2 12.4 0.0 2.1 0.3 11.4 0.3 1.4 6.5 0.1 0.1 0.0 54.4 39.4 1.2 0.0 0.1 8.2 0.4 0.3 0.0 43.9 0.4 4.6 0.1 63.8 172.6 0.0 16.6 17.4 7.0 0.0 0.0 12.9 10.9 0.1 0.0 34.3 11.1 10.2 6.0 5.3 45.2 0.1 0.0 21.1 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.3 20.6 3.5 45.7 20.6 9.6 13.9 10.2 12.9 1.6 17.4 24.0 1.6 0.0 0.0 41.8 0.4 0.4 0.9 0.1 0.6 39.3 0.0 0.1 62.8 0.0 0.0 1.8 2.1 0.0 0.1 0.0 0.0 0.0 17.6 0.3 7.7 2.7 1.8 0.0 410.0 0.0 0.0 4.3 0.0 0.2 0.0 15.0 0.0 0.1 0.0 3.3 236.6 0.0 0.0 0.0 0.3 57.7 0.6 0.1 3.6 10.3 0.0 4.1 0.0 127.2 22.3 0.1 1.1 3.0 0.0 0.5 0.0 0.0 0.7 6.8 0.0 14.2 2.2 5.1 4.7 1.5 0.4 0.1 2.0 45.2 0.0 0.1 ADCK1 FLJ39600 ENSG00000063761 "AarF domain containing kinase 1" Q86TW2 14 77800109-77935014 "Enzymes, Predicted secreted proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9;Oligodendrocytes: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051012, HPA055014" Uncertain Uncertain Nucleoplasm "Secreted - unknown location" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA051012: AB_2681310, HPA055014: AB_2682672" "unprognostic (6.36e-2)" "unprognostic (7.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.70e-4)" "prognostic favorable (4.11e-5)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (4.57e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.82e-6)" "unprognostic (6.30e-3)" "unprognostic (2.06e-1)" "unprognostic (9.57e-2)" "unprognostic (4.06e-1)" 4.4 8.1 7.3 3.7 7.8 5.3 4.2 7.3 10.3 4.3 8.2 6.7 7.4 4.8 5.1 6.1 4.4 3.8 9.0 7.8 7.2 7.0 8.6 4.0 4.1 7.8 7.4 4.7 6.7 6.5 8.3 5.1 8.2 6.5 5.8 3.8 6.7 5.4 8.9 6.3 5.6 6.4 7.1 7.3 6.1 4.6 7.9 5.2 5.9 5.2 4.8 5.1 4.0 10.2 5.5 9.1 4.4 17.4 13.0 6.5 6.2 5.7 7.9 4.5 5.6 4.7 12.4 12.0 8.5 9.5 7.5 10.2 27.0 9.3 2.9 6.3 9.1 2.8 4.9 7.5 12.2 4.5 6.6 7.7 16.2 1.9 5.7 4.4 7.1 10.1 11.4 7.4 5.9 24.5 5.8 7.6 9.6 17.5 10.2 9.1 0.7 9.0 6.6 13.9 10.4 6.0 10.6 14.7 5.9 6.8 20.9 9.4 6.8 4.6 3.4 8.9 4.6 6.4 7.7 6.3 6.6 7.7 5.8 1.3 4.0 1.4 4.2 6.0 2.9 1.4 1.6 2.4 7.4 3.0 1.9 3.4 0.3 3.2 2.5 5.5 3.1 2.5 7.3 7.8 7.3 10.3 7.8 7.2 7.8 7.4 8.2 7.1 7.9 10.2 1.9 0.0 3.7 10.1 1.8 0.9 1.8 3.9 2.8 5.9 2.9 3.0 5.7 4.3 2.8 0.0 20.9 8.2 4.2 4.0 3.9 4.4 1.5 2.0 2.4 1.4 1.8 2.1 10.3 5.1 4.2 2.4 6.6 2.4 1.3 5.0 1.8 6.6 9.6 8.4 11.7 4.0 4.1 4.4 1.5 0.8 1.5 5.1 0.0 5.6 2.5 4.0 3.1 11.6 29.0 2.8 1.3 1.9 3.2 1.5 3.0 3.8 2.4 9.3 0.0 2.1 1.6 1.8 9.9 4.3 1.4 5.3 2.2 4.6 5.4 1.2 ADI1 "APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL" ENSG00000182551 "Acireductone dioxygenase 1" Q9BV57 2 3497366-3519531 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 590.7" "Cell type enhanced" "Detected in all" "Distal tubular cells: 888.3;Hepatocytes: 1234.6;Proximal tubular cells: 1546.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035403, HPA035404" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus" "HPA035403: AB_10603576, HPA035404: AB_2674611" "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (4.23e-3)" "unprognostic (2.36e-3)" "unprognostic (4.00e-3)" "unprognostic (2.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (9.94e-2)" "unprognostic (6.76e-2)" "unprognostic (8.74e-2)" 55.1 76.9 31.1 28.0 32.6 31.7 50.4 31.7 42.1 54.2 43.3 58.3 105.2 45.6 43.3 48.2 45.2 66.7 146.4 32.0 31.0 200.2 590.7 44.6 30.1 33.0 32.2 50.0 34.9 49.6 33.5 41.3 33.6 101.1 52.3 17.1 53.6 55.9 121.1 35.7 68.9 37.9 31.6 57.2 82.4 16.7 31.6 26.9 36.5 56.0 34.5 57.9 36.5 34.7 46.5 64.5 55.9 50.2 187.5 85.0 91.9 95.6 124.1 102.7 74.5 86.9 59.2 22.1 143.4 109.5 21.4 45.1 62.9 49.0 59.2 39.5 131.4 67.6 42.2 184.1 165.4 71.2 151.3 91.4 72.3 55.0 63.7 45.3 75.8 36.1 51.8 45.3 87.4 137.8 25.6 147.1 44.4 131.9 86.4 27.1 31.3 128.2 90.2 83.3 57.0 54.0 53.0 75.0 37.2 36.8 55.6 95.5 54.1 75.9 29.0 35.9 56.6 35.4 91.6 88.7 58.6 115.5 41.0 87.6 134.3 336.9 28.5 126.5 31.8 66.8 67.4 26.7 127.7 53.4 79.3 25.6 59.4 54.5 117.4 186.3 67.4 189.0 31.1 32.6 31.7 42.1 32.0 31.0 33.0 32.2 33.6 31.6 31.6 34.7 44.8 67.3 111.1 25.1 73.1 76.0 154.5 107.8 92.2 9.2 103.0 88.9 275.8 338.8 109.5 152.6 14.6 395.0 80.6 140.1 888.3 157.2 8.8 65.9 116.3 61.6 57.2 123.1 9.4 87.2 247.1 129.1 66.3 116.3 41.8 75.1 207.8 1234.6 263.2 8.4 15.0 146.1 236.0 168.8 67.6 23.8 137.0 90.0 204.5 7.5 108.2 197.2 40.2 5.5 19.0 79.7 272.5 210.3 97.4 143.6 409.8 1546.8 38.0 15.3 164.3 45.5 109.3 5.3 11.3 113.6 76.9 381.4 53.0 120.8 147.2 156.9 ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8;testis: 21.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;granulocytes: 22.3;Muller glia cells: 44.4;Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 31.5" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.3;MCF7: 24.4;RH-30: 65.4;RPTEC TERT1: 31.7;SK-BR-3: 35.2;U-138 MG: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" 3.7 0.2 31.9 1.6 34.6 0.0 4.6 28.6 33.8 1.0 0.0 1.0 1.0 1.2 0.6 1.1 1.2 0.9 11.4 29.6 23.0 9.3 0.4 1.7 0.6 35.7 35.0 0.3 13.2 8.0 1.9 6.8 41.8 1.0 0.6 4.8 6.4 0.4 1.7 4.6 1.2 0.4 23.6 6.3 1.0 21.4 54.8 0.4 2.2 2.5 0.5 1.6 0.7 41.5 0.3 3.0 0.6 0.2 0.2 1.6 0.2 2.0 3.0 0.7 0.4 40.3 0.7 0.0 8.9 7.3 4.8 0.1 0.7 0.0 0.2 0.0 1.1 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.9 0.0 6.4 0.0 6.4 0.0 0.1 6.2 24.4 0.1 0.0 10.2 0.0 0.0 0.0 65.4 2.3 31.7 0.0 0.8 0.7 4.4 35.2 0.5 3.6 2.0 1.0 0.0 20.9 10.6 0.0 11.7 0.0 0.2 0.0 10.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 34.6 28.6 33.8 29.6 23.0 35.7 35.0 41.8 23.6 54.8 41.5 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.1 9.4 6.9 3.1 7.2 0.0 3.7 0.0 0.1 0.1 0.1 0.0 11.7 0.1 0.0 0.4 0.3 0.0 0.0 18.1 3.3 1.3 1.1 0.0 0.1 22.3 0.8 0.0 0.0 0.9 0.0 2.9 0.0 0.0 1.0 1.0 0.5 0.0 0.6 1.8 1.9 0.2 44.4 0.0 35.2 31.5 0.5 0.0 0.7 0.0 0.0 0.0 3.0 0.0 1.6 0.0 0.0 0.6 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 235.8" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 245.4;Proximal tubular cells: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060766 Approved Approved "Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA060766: AB_2684356" "unprognostic (2.70e-2)" "prognostic unfavorable (3.26e-6)" "unprognostic (4.27e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.34e-2)" "prognostic unfavorable (3.25e-7)" "unprognostic (1.91e-2)" "unprognostic (8.75e-3)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.74e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (9.11e-2)" "unprognostic (2.75e-1)" 42.0 29.8 43.7 10.4 44.6 31.6 30.0 43.3 46.1 17.6 48.2 23.0 46.6 14.4 33.0 34.1 34.4 24.5 54.1 44.1 49.1 102.0 235.8 19.9 10.7 45.0 43.4 34.7 31.0 31.0 36.6 11.9 46.4 22.7 18.8 33.9 19.8 24.1 23.7 16.8 45.9 15.2 47.1 20.1 20.8 15.7 51.0 6.8 42.9 32.5 14.8 29.4 26.1 52.5 32.6 25.2 20.6 56.9 29.7 22.3 7.6 28.3 57.1 26.8 61.9 37.5 81.5 20.0 40.5 66.1 41.7 42.0 26.5 79.2 64.2 67.2 63.0 5.6 35.6 157.3 40.8 46.0 2.7 32.9 76.7 35.7 129.6 88.2 10.9 30.8 4.0 67.6 59.3 45.6 14.2 9.8 40.8 37.4 27.6 20.2 61.6 36.6 100.6 77.6 75.5 42.4 35.5 33.2 17.2 36.0 31.7 96.0 3.0 25.2 27.8 22.7 33.4 99.6 95.1 2.1 59.7 9.5 26.9 12.0 6.2 9.6 6.6 29.3 15.1 9.6 12.4 10.6 33.0 5.6 13.1 10.0 11.3 11.8 35.4 2.9 9.7 9.2 43.7 44.6 43.3 46.1 44.1 49.1 45.0 43.4 46.4 47.1 51.0 52.5 40.8 16.0 27.7 114.9 22.0 25.0 51.8 82.5 27.9 68.3 69.9 65.4 73.7 72.9 66.9 51.5 25.0 79.6 8.6 12.6 52.8 60.3 22.4 99.8 25.9 32.8 39.5 29.3 204.3 31.5 10.5 42.2 26.0 83.1 36.8 90.9 36.8 229.6 32.7 53.8 245.4 33.3 59.0 40.1 42.3 7.0 32.0 37.2 55.2 100.2 18.2 74.3 8.2 105.1 172.9 25.8 65.2 38.4 47.7 35.3 232.9 261.5 69.1 36.9 32.9 41.7 50.8 5.6 17.3 53.1 45.7 108.1 18.5 61.5 42.4 53.2 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AKAP1 "AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, S-AKAP84, SAKAP84, TDRD17" ENSG00000121057 "A-kinase anchoring protein 1" Q92667 17 57085092-57121346 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.8" "Group enriched" "Detected in all" 9 "Early spermatids: 584.7;Late spermatids: 2219.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008620, HPA008691, CAB019286" Supported Supported Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB019286: , HPA008620: AB_2668104, HPA008691: AB_1078119" "unprognostic (5.52e-2)" "unprognostic (1.83e-1)" "unprognostic (6.96e-3)" "unprognostic (1.78e-1)" "unprognostic (1.79e-2)" "unprognostic (6.38e-2)" "unprognostic (7.19e-2)" "unprognostic (1.48e-2)" "unprognostic (8.14e-2)" "unprognostic (2.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.00e-1)" "prognostic favorable (7.86e-9)" "unprognostic (6.82e-2)" "unprognostic (2.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.38e-1)" 40.6 15.5 31.6 17.8 35.2 6.9 35.2 29.1 35.2 23.7 17.2 76.1 54.8 24.5 19.7 36.4 31.5 18.0 82.6 28.5 26.5 26.2 49.9 19.6 10.8 26.7 27.1 20.0 22.2 48.1 17.1 7.1 26.9 34.7 48.9 34.7 33.6 24.8 207.8 27.3 55.8 26.3 21.9 11.3 55.4 112.9 29.8 11.4 36.3 137.9 9.5 46.8 25.5 28.0 46.1 54.3 80.7 27.5 18.2 12.8 46.8 19.0 18.3 24.2 16.8 61.2 42.2 74.1 52.3 14.5 26.5 74.6 50.1 44.4 24.7 40.6 63.5 63.1 51.4 118.1 19.4 59.9 23.8 11.7 41.8 26.2 39.2 14.4 25.7 22.9 42.3 28.6 14.8 39.8 76.1 24.1 28.7 97.9 61.7 58.2 32.8 61.0 17.1 61.9 58.9 40.3 15.8 45.1 23.9 16.6 31.4 61.4 18.8 24.3 24.2 28.3 45.0 28.9 36.9 55.8 14.0 47.5 19.7 1.6 1.0 0.4 2.6 2.0 2.3 1.8 2.0 2.1 2.3 1.2 4.0 2.1 0.1 3.3 0.5 4.0 1.7 1.3 31.6 35.2 29.1 35.2 28.5 26.5 26.7 27.1 26.9 21.9 29.8 28.0 34.5 35.3 49.9 26.4 16.6 22.6 23.5 11.9 32.5 33.0 29.4 42.3 154.9 28.6 32.1 5.5 47.9 21.5 10.6 89.1 1.9 16.3 584.7 16.8 12.6 16.4 45.9 12.6 14.9 16.3 13.8 12.2 54.0 37.8 3.8 21.0 11.4 60.2 9.5 37.0 26.3 86.6 8.2 9.0 9.5 2219.5 19.6 10.9 7.2 4.7 8.7 8.2 3.1 10.6 9.6 12.7 68.5 13.9 13.2 32.3 65.6 7.4 6.5 77.1 46.0 17.9 54.4 18.3 14.9 44.9 19.7 6.8 11.5 13.3 117.6 17.0 ALAS1 "ALAS, ALAS3" ENSG00000023330 "5'-aminolevulinate synthase 1" P13196 3 52198086-52214327 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 720.5;liver: 548.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 243.1;Syncytiotrophoblasts: 309.2;Theca cells: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 233.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 233.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017498, HPA035860" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria Nucleoplasm "CAB017498: AB_2225629, HPA035860: AB_10672992" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (7.09e-2)" "unprognostic (2.33e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.82e-5)" "unprognostic (3.98e-2)" "unprognostic (1.26e-1)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (5.64e-2)" "prognostic favorable (6.06e-7)" "unprognostic (8.45e-2)" "unprognostic (3.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" 34.5 720.5 24.8 23.9 25.1 176.7 28.7 37.9 82.5 20.5 35.7 43.6 44.9 19.0 28.1 36.4 15.3 32.7 116.2 26.6 28.1 45.7 548.8 47.8 22.9 27.2 25.4 17.1 19.6 60.3 15.7 36.8 33.2 23.1 41.6 20.6 42.8 27.2 110.9 24.3 39.3 23.9 24.9 19.5 45.9 18.6 31.8 23.5 22.1 106.6 28.2 73.8 23.5 28.3 36.2 55.0 38.0 35.4 57.9 43.1 103.1 51.8 47.7 67.6 65.3 73.6 66.2 33.6 12.7 36.4 137.0 20.9 55.1 42.6 54.7 65.9 21.6 43.2 41.2 56.4 81.8 70.8 83.0 54.0 39.1 107.7 35.7 25.0 62.8 57.7 25.8 27.0 62.4 29.5 33.9 107.3 33.0 41.1 93.4 20.0 23.9 53.3 59.8 213.9 20.2 13.3 83.9 40.9 47.2 30.5 23.5 99.9 45.7 37.6 37.1 78.5 76.2 39.5 73.8 50.5 42.1 75.5 61.1 233.9 33.4 103.2 22.9 42.9 37.4 23.1 23.9 26.0 29.8 21.5 21.1 23.3 49.6 30.9 39.0 17.1 35.7 25.1 24.8 25.1 37.9 82.5 26.6 28.1 27.2 25.4 33.2 24.9 31.8 28.3 28.4 35.3 60.3 5.2 14.9 17.3 17.2 36.1 15.9 16.6 28.6 19.6 107.5 25.8 37.7 23.9 4.2 81.9 25.1 68.5 56.7 35.5 10.2 20.2 9.3 27.6 34.6 11.2 6.2 31.3 28.2 19.6 42.3 25.3 95.4 13.1 18.5 243.1 69.1 11.8 6.2 24.3 34.6 13.0 20.8 4.1 13.4 36.4 5.4 8.4 49.1 9.7 11.3 4.0 8.4 42.3 28.1 16.6 14.0 16.0 35.6 36.1 40.6 9.2 13.1 9.1 27.5 25.5 22.3 21.4 16.2 309.2 25.1 187.2 24.3 26.4 ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 369.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 633.3;Proximal tubular cells: 197.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.5;Hep G2: 78.1;Karpas-707: 82.0;RPMI-8226: 45.0;RT4: 219.1;U-266/70: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 3000000 "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favorable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" 76.4 37.2 53.4 2.0 63.2 0.4 28.8 55.9 63.6 15.6 37.7 10.1 0.2 7.2 2.5 6.6 16.0 2.3 26.5 47.5 56.2 116.6 369.7 3.1 0.3 56.7 52.9 45.3 44.3 15.1 4.5 0.0 53.0 14.6 5.4 8.7 88.6 6.9 90.7 3.5 5.6 2.0 48.4 0.4 9.5 15.0 53.9 3.7 2.6 59.9 4.6 28.3 6.4 46.0 1.3 0.0 0.0 0.0 36.5 0.0 0.4 0.3 1.5 0.4 0.6 0.0 3.2 2.6 10.2 0.0 2.1 0.4 0.6 1.5 0.7 0.0 0.2 0.1 0.3 78.1 10.6 10.6 0.2 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 82.0 1.6 0.0 0.0 0.2 0.3 1.1 0.0 0.1 0.2 45.0 0.7 219.1 0.4 0.3 1.3 10.6 0.0 0.6 0.1 0.0 0.3 1.4 6.2 0.0 0.1 44.8 14.8 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 63.2 55.9 63.6 47.5 56.2 56.7 52.9 53.0 48.4 53.9 46.0 0.8 0.0 6.0 92.7 4.6 0.1 53.5 9.1 1.8 0.2 14.4 2.2 16.1 38.6 44.0 12.9 0.0 0.0 0.1 7.2 72.4 2.9 22.3 57.2 5.2 4.6 1.2 34.7 0.6 5.6 0.2 9.1 0.0 3.6 27.8 12.4 17.2 633.3 0.1 0.0 3.0 17.6 2.0 24.5 1.9 35.0 26.4 9.3 3.6 3.7 0.0 40.0 0.0 11.1 0.2 2.2 0.4 22.6 0.0 12.2 0.8 197.4 32.2 1.4 6.6 10.5 5.3 1.6 4.3 1.7 0.0 0.1 2.8 0.9 5.6 61.7 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Cell line enhanced" "Detected in many" "ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 303.8 102.4 139.7 39.8 146.1 29.2 77.2 136.5 163.5 25.0 123.3 73.3 73.7 30.1 21.3 73.6 32.3 37.4 111.3 132.2 139.7 177.7 857.7 111.6 18.7 140.7 144.9 42.0 23.3 2.6 23.3 7.0 141.1 34.6 72.3 29.2 32.4 29.5 130.8 127.9 74.8 30.2 143.0 20.6 101.5 13.0 151.8 27.1 30.8 165.7 52.9 50.0 29.0 144.5 8.8 13.1 18.7 31.9 86.8 13.0 60.9 9.3 16.8 4.3 3.1 23.5 12.1 0.5 45.3 20.8 11.9 16.2 0.1 4.6 2.7 0.6 6.1 0.7 8.4 64.7 97.0 0.9 0.9 23.9 22.6 14.8 0.3 17.7 26.9 0.9 17.9 3.0 4.1 0.5 1.0 23.4 24.8 152.2 2.1 0.6 0.4 1.9 31.4 0.6 7.5 23.1 22.8 201.0 0.2 33.7 20.3 92.1 1.1 0.4 16.5 0.6 0.4 5.5 3.0 25.7 22.0 0.8 0.4 6.5 212.0 51.1 0.7 93.0 0.9 6.2 0.3 0.7 213.2 5.2 0.7 0.5 10.7 3.4 25.4 70.6 0.5 123.5 139.7 146.1 136.5 163.5 132.2 139.7 140.7 144.9 141.1 143.0 151.8 144.5 27.7 147.4 242.7 51.2 22.6 60.0 205.2 311.1 80.8 78.7 35.0 23.7 378.9 165.8 243.1 66.2 18.8 62.4 48.6 260.3 399.2 127.5 4.3 27.8 24.5 66.2 55.2 42.1 11.7 218.0 127.5 103.1 200.3 47.7 30.9 29.0 139.6 857.0 129.2 35.3 18.2 231.0 101.7 278.5 124.1 10.6 79.9 189.3 35.6 26.2 940.8 130.2 8.2 14.1 6.8 130.2 366.5 149.0 12.5 84.4 384.3 882.0 89.4 42.6 46.0 46.0 67.6 3.0 3.9 105.1 124.7 42.1 13.1 81.0 272.6 150.4 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 200.4;liver: 436.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 83.7;SK-BR-3: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 58000 "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: " "unprognostic (1.17e-1)" "prognostic favorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 70.8 16.1 73.9 3.9 88.9 11.7 21.6 73.8 95.9 12.6 106.5 6.8 1.6 9.8 4.7 36.3 8.3 5.5 33.0 68.2 73.8 200.4 436.6 6.2 3.4 72.9 82.8 7.3 4.6 23.0 9.7 13.2 70.0 29.5 2.7 6.5 9.1 27.1 74.2 19.2 4.7 7.1 65.6 7.5 12.5 3.2 92.4 11.7 7.1 74.8 4.2 19.3 16.8 66.1 12.7 17.8 9.5 29.2 40.0 5.7 25.2 13.1 7.1 11.8 9.5 13.7 8.9 8.8 16.6 15.6 5.7 34.0 16.7 35.4 4.5 4.8 15.9 5.9 5.0 83.7 12.6 4.4 15.1 15.6 19.2 6.5 6.6 9.0 13.5 14.0 21.0 5.7 8.1 32.3 4.3 20.2 4.7 26.0 10.1 27.9 8.4 10.0 12.1 32.0 19.6 7.6 21.9 85.0 16.1 14.7 38.7 6.3 11.3 10.2 14.0 12.2 4.5 7.1 17.9 2.5 3.4 33.7 13.5 0.0 2.7 1.5 0.6 3.6 0.5 0.8 0.3 0.8 4.4 0.7 0.2 0.5 0.3 0.1 2.0 1.5 0.6 1.5 73.9 88.9 73.8 95.9 68.2 73.8 72.9 82.8 70.0 65.6 92.4 66.1 2.6 0.0 2.8 27.1 4.3 7.5 17.9 12.5 17.6 3.7 9.8 8.5 20.9 34.3 2.9 46.0 10.4 78.0 2.0 2.0 46.9 6.5 0.5 1.1 1.7 3.1 2.4 32.2 1.2 0.9 12.6 3.2 7.7 3.9 4.5 2.1 15.4 385.1 13.8 20.2 1.6 3.6 6.1 17.2 1.4 0.6 1.2 4.7 3.6 1.9 10.9 14.0 1.0 5.5 1.3 2.5 1.8 2.6 4.4 12.0 0.3 279.4 1.7 4.8 6.6 2.6 4.7 2.2 3.9 21.7 5.4 86.6 2.6 4.5 4.0 9.5 ALDH5A1 "SSADH, SSDH" ENSG00000112294 "Aldehyde dehydrogenase 5 family member A1" P51649 6 24494867-24537207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 98.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 136.6;U-698: 173.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029715, HPA029716" Enhanced Supported Mitochondria NA NA 50000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA029715: AB_10599994, HPA029716: AB_10601876" "unprognostic (7.43e-2)" "unprognostic (1.12e-3)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "prognostic favorable (7.61e-6)" "unprognostic (2.38e-2)" "unprognostic (2.17e-2)" "prognostic favorable (6.20e-4)" "unprognostic (1.43e-2)" "unprognostic (1.21e-1)" "prognostic favorable (3.68e-4)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-2)" "unprognostic (1.08e-2)" 9.4 6.1 27.8 5.9 28.9 4.4 5.2 25.0 32.7 5.4 18.8 8.5 11.8 4.8 3.7 7.3 19.0 5.1 14.5 26.5 32.8 27.8 98.8 6.4 13.6 26.7 35.0 7.3 8.2 19.4 5.8 2.4 27.3 8.2 7.1 11.0 5.2 5.2 57.9 9.5 8.0 3.1 29.4 6.8 7.7 4.5 34.0 26.8 17.0 33.8 12.9 6.7 8.4 24.9 11.5 9.3 6.5 10.1 0.1 0.0 11.7 0.8 2.0 2.4 1.6 35.1 2.5 136.6 21.1 1.0 2.2 0.1 10.5 1.3 1.5 14.7 20.2 20.7 5.9 42.4 1.6 32.2 2.7 1.0 4.4 0.2 0.0 7.1 0.1 34.7 10.4 0.0 1.8 23.3 40.4 19.0 2.7 18.4 5.5 46.1 1.4 1.3 7.7 19.6 11.7 10.5 12.1 1.2 13.2 2.8 19.4 17.5 0.2 1.1 6.7 0.3 7.1 19.4 32.2 173.7 0.2 9.8 1.4 0.3 0.0 0.1 1.0 0.0 1.9 2.2 1.4 1.5 0.1 2.0 3.8 3.4 0.2 0.8 0.1 2.4 0.9 0.7 27.8 28.9 25.0 32.7 26.5 32.8 26.7 35.0 27.3 29.4 34.0 24.9 2.9 16.0 25.3 14.0 9.7 1.7 5.6 8.2 2.2 12.9 7.5 3.4 34.8 11.5 9.4 7.3 16.7 6.1 7.4 6.1 1.9 1.6 0.8 15.2 5.0 3.7 8.4 16.0 18.1 1.0 5.2 3.5 5.6 5.4 7.0 13.5 6.8 90.7 3.9 16.8 32.4 11.7 2.0 3.8 1.8 0.3 3.4 1.7 1.8 8.4 0.2 11.8 3.1 11.6 2.4 1.3 7.7 4.5 12.2 4.1 13.4 26.8 12.8 6.9 0.0 6.9 2.3 1.7 6.6 8.7 3.0 1.9 5.4 8.0 17.0 13.1 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Cell line enhanced" "Detected in all" "T-47d: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 38.7 14.7 58.6 4.8 66.0 3.3 14.4 58.8 59.3 17.3 61.4 15.2 26.6 11.4 9.8 9.8 12.8 9.4 40.3 51.0 54.0 379.1 367.1 9.4 5.1 63.3 54.0 28.3 23.4 37.0 6.6 7.6 55.6 25.4 15.8 15.2 19.8 16.1 27.5 6.2 23.4 9.0 56.4 5.4 24.0 17.1 69.8 5.7 28.3 34.8 5.3 11.4 7.0 62.6 8.9 7.8 11.0 23.5 39.3 19.2 17.5 6.3 11.8 6.8 11.5 17.3 10.2 10.5 13.6 13.5 5.3 4.8 24.9 7.0 14.5 9.5 3.5 5.1 8.0 19.2 45.0 2.7 2.4 28.2 12.0 8.7 20.7 17.0 12.0 23.7 8.1 14.7 4.6 36.2 7.6 4.0 8.7 32.6 5.2 15.1 11.2 14.6 9.2 5.8 4.4 7.0 21.0 21.9 5.7 18.0 57.5 9.6 3.8 7.4 9.0 11.7 2.4 9.3 18.9 10.2 9.9 3.2 7.3 29.1 6.2 43.2 6.9 4.8 10.6 7.2 7.8 8.4 9.2 6.1 9.9 7.0 2.4 9.7 4.2 5.3 6.1 4.9 58.6 66.0 58.8 59.3 51.0 54.0 63.3 54.0 55.6 56.4 69.8 62.6 15.4 38.5 60.4 24.5 11.8 9.2 26.8 10.0 20.5 20.6 28.4 18.9 81.4 67.2 22.9 66.2 4.2 31.0 7.1 18.9 201.5 11.6 23.4 26.2 27.5 27.0 16.9 28.6 5.5 3.1 14.8 25.9 34.7 90.2 7.6 27.1 87.4 523.6 17.7 11.8 10.0 39.3 8.2 26.5 8.9 19.0 28.9 13.4 24.9 1.9 15.8 98.5 9.2 12.5 23.4 4.1 16.3 48.2 8.0 27.6 55.3 962.4 15.4 17.0 13.1 25.6 16.9 11.0 4.2 25.2 7.4 30.6 11.0 10.2 35.7 17.2 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 162.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 414.1;Proximal tubular cells: 302.1;Syncytiotrophoblasts: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 256.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 23.7 38.3 46.6 9.1 47.6 1.8 47.1 43.7 45.8 32.7 40.7 29.5 23.7 25.1 8.8 35.9 28.8 19.1 27.9 44.7 43.2 115.1 162.2 15.7 8.6 43.1 43.5 65.3 27.0 34.0 8.8 44.9 42.6 42.0 27.4 19.7 40.6 27.9 12.2 29.4 21.0 23.6 44.8 7.0 23.6 12.3 44.0 18.3 47.6 26.5 17.1 18.1 20.9 45.2 64.9 41.9 116.6 193.4 95.5 56.4 147.8 76.1 93.4 86.5 110.5 118.6 60.7 0.0 75.5 60.0 36.1 47.1 36.5 256.2 78.8 0.1 44.6 12.3 63.1 102.1 46.3 0.2 0.0 69.0 59.2 67.3 47.7 64.2 70.0 0.0 0.0 0.1 77.1 42.1 2.6 0.3 79.4 47.5 35.2 38.9 131.8 0.0 81.2 48.4 39.4 47.2 0.0 41.1 44.7 89.0 75.2 2.7 86.1 24.8 75.6 28.8 53.1 0.1 0.1 0.4 13.4 0.2 40.6 0.7 0.2 0.1 0.1 0.0 0.2 0.8 0.2 0.1 1.8 0.6 1.2 0.6 0.1 0.1 0.0 6.4 0.0 0.4 46.6 47.6 43.7 45.8 44.7 43.2 43.1 43.5 42.6 44.8 44.0 45.2 17.6 16.0 29.3 99.3 5.0 25.9 59.5 110.0 87.0 23.6 40.6 91.1 39.9 27.1 43.5 42.3 22.9 414.1 3.7 15.2 76.3 43.5 31.4 18.7 44.3 19.1 21.7 5.2 16.0 13.8 107.8 34.0 27.0 21.4 7.0 50.4 18.9 74.6 51.1 25.2 21.5 25.9 20.3 9.4 7.6 41.7 25.4 9.1 55.2 12.2 7.5 102.1 0.0 41.7 30.0 12.6 15.6 37.2 2.0 27.5 23.4 302.1 23.4 13.6 19.7 19.4 25.8 1.0 5.1 59.2 16.1 222.3 4.6 39.3 46.4 50.4 ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 26754.8;tongue: 9180.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 3267.9;Extravillous trophoblasts: 2322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004177, CAB006252" Supported Approved Cytosol NA NA 640000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB006252: AB_437007, HPA004177: AB_1078128" "unprognostic (2.63e-2)" "unprognostic (3.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (6.74e-3)" "unprognostic (4.28e-3)" "prognostic unfavorable (5.79e-5)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.68e-1)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-3)" "unprognostic (4.48e-2)" 569.3 696.4 616.8 443.1 697.4 732.5 512.6 617.3 719.7 566.0 617.0 774.1 517.9 533.7 201.0 1302.0 449.7 420.5 2286.1 731.9 652.0 709.0 217.1 425.6 358.2 762.3 654.0 510.4 390.5 943.1 525.1 351.4 763.9 457.7 400.1 465.2 904.9 597.6 26754.8 643.4 488.3 465.2 545.5 417.5 595.0 138.7 657.8 280.9 454.5 9180.4 478.3 761.8 740.3 558.7 2206.1 1620.4 477.9 1542.8 714.6 808.5 1520.8 1297.9 1336.2 1291.6 1603.0 1158.1 1643.6 1487.6 2072.2 1318.6 708.6 1632.6 966.8 2829.1 939.3 658.5 1272.9 1219.3 1202.7 2591.1 1112.5 1793.8 1251.3 1115.7 979.6 1455.4 968.9 2119.7 965.4 686.9 1070.0 951.1 1393.4 3136.7 1100.2 1477.0 1192.8 848.1 1346.6 1613.9 765.2 3353.2 1629.4 1230.5 950.7 668.5 808.6 3368.5 1213.9 591.2 1433.0 1194.7 1162.5 1892.3 750.3 1046.7 1430.0 1861.5 1387.3 1369.3 3524.5 1715.9 1532.9 2050.6 2694.7 2081.7 1008.7 2466.5 1138.1 908.5 1091.7 1047.0 2182.7 877.9 1027.4 996.9 2531.7 819.9 2780.2 824.0 1476.3 4372.2 616.8 697.4 617.3 719.7 731.9 652.0 762.3 654.0 763.9 545.5 657.8 558.7 17.0 12.8 32.4 83.2 281.2 792.0 716.4 3267.9 784.8 387.4 34.4 21.6 1968.4 273.1 1385.1 42.3 118.9 1194.1 107.9 1834.8 111.6 120.9 258.8 15.8 11.8 261.1 323.9 215.8 66.2 76.2 2322.1 329.7 513.3 16.1 196.5 18.7 289.5 102.0 1181.9 733.6 70.0 755.1 1265.4 632.2 715.4 1152.4 380.8 388.8 924.9 50.6 417.7 662.1 328.5 40.2 60.8 126.2 1497.1 405.1 409.4 676.9 1755.7 75.8 700.9 298.9 486.4 680.9 572.9 25.8 123.6 1174.6 684.5 1361.3 294.3 15.2 937.7 1146.2 ALKBH7 "MGC10974, SPATA11" ENSG00000125652 "AlkB homolog 7" Q9BT30 19 6372794-6375250 "Predicted intracellular proteins" Necrosis "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 517.8" "Group enriched" "Detected in all" 4 "Early spermatids: 3004.6;Late spermatids: 8717.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008539, HPA039571, HPA039872" Approved Supported Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA008539: , HPA039571: AB_2676577, HPA039872: AB_10697710" "unprognostic (5.38e-2)" "unprognostic (3.58e-2)" "unprognostic (2.20e-1)" "unprognostic (1.15e-2)" "unprognostic (7.79e-2)" "unprognostic (3.56e-3)" "unprognostic (1.06e-1)" "unprognostic (1.35e-1)" "unprognostic (3.02e-1)" "unprognostic (6.83e-2)" "unprognostic (1.72e-3)" "unprognostic (1.54e-1)" "prognostic favorable (7.83e-6)" "unprognostic (7.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" 48.9 64.5 59.8 19.2 62.3 31.1 51.3 65.7 74.2 54.6 69.5 72.5 65.8 48.4 14.6 66.1 55.4 19.2 157.2 56.6 61.3 86.0 152.9 40.4 26.9 64.0 61.3 68.8 112.3 44.9 67.5 14.3 61.0 70.1 20.0 15.8 65.2 30.5 154.4 61.0 61.5 12.8 63.6 46.6 68.4 517.8 61.6 28.1 73.0 67.4 15.9 52.1 51.6 68.5 28.9 25.2 21.4 37.1 11.8 32.7 30.9 20.5 18.0 18.1 19.1 44.0 18.3 42.1 68.4 26.2 12.8 22.1 9.6 17.1 3.5 40.9 38.9 24.5 17.6 41.4 34.5 12.4 31.3 37.6 33.8 15.7 12.3 17.5 22.5 40.7 26.2 80.0 13.9 58.3 63.5 42.6 30.8 33.9 106.1 46.6 13.4 84.2 20.4 22.1 30.3 46.3 13.8 36.1 76.4 10.1 41.0 44.7 20.3 18.0 25.0 66.9 20.1 129.2 98.1 27.7 33.9 41.9 15.9 38.3 106.4 17.3 52.7 91.6 72.9 113.4 91.4 72.5 127.6 103.0 137.4 111.1 64.4 66.1 72.0 143.9 85.7 91.5 59.8 62.3 65.7 74.2 56.6 61.3 64.0 61.3 61.0 63.6 61.6 68.5 84.8 60.9 74.4 3.3 109.0 83.7 154.4 129.1 160.5 93.1 221.6 335.4 106.3 112.9 83.9 66.2 66.7 97.6 79.3 516.1 313.1 110.1 3004.6 76.1 73.0 84.8 220.4 54.0 2.4 245.2 149.6 88.0 77.5 85.1 66.0 108.3 113.2 302.0 196.8 42.1 3.5 400.4 71.2 168.6 96.2 8717.7 103.2 128.6 133.4 1.9 192.6 166.1 69.0 3.0 9.3 116.0 528.2 88.8 121.0 121.1 856.4 433.6 52.7 152.4 92.1 97.2 104.1 1180.3 76.7 171.2 100.6 108.9 87.4 143.4 410.5 215.6 ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58629091 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 41.9;skeletal muscle: 38.3;tongue: 33.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 120.4;Cone photoreceptor cells: 47.9;Early spermatids: 15.9;Late spermatids: 24.3;monocytes: 18.1" "Cancer enriched" "Detected in some" 6 "renal cancer: 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 51.2;BJ hTERT+: 31.0;fHDF/TERT166: 46.6;U-138 MG: 25.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006" "unprognostic (7.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.60e-3)" "unprognostic (2.64e-1)" "unprognostic (8.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (5.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (3.20e-2)" 0.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.3 0.0 0.9 41.9 0.4 0.0 9.2 4.5 0.1 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 2.1 0.3 0.0 38.3 0.5 1.0 0.1 0.0 0.5 1.7 1.1 0.0 3.5 0.0 33.2 4.4 1.5 0.0 0.0 0.0 13.7 0.9 0.0 0.4 3.4 0.3 51.2 31.0 21.2 18.1 3.4 0.0 0.0 5.2 46.6 2.9 0.0 0.0 0.0 21.5 11.5 0.0 0.0 4.4 1.8 2.7 0.0 0.0 3.0 0.0 6.4 0.2 0.7 0.0 0.0 0.0 0.4 13.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 11.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 8.3 0.0 0.0 0.0 25.3 11.2 3.5 8.7 20.9 19.2 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.1 4.8 120.4 0.0 0.0 0.0 47.9 0.0 0.1 0.0 1.9 1.5 15.9 0.0 2.3 0.9 0.0 0.0 1.0 0.7 0.0 8.9 0.0 0.1 0.0 4.0 0.4 3.0 0.7 1.7 0.7 0.0 0.0 0.3 3.0 24.3 0.3 2.4 0.0 0.0 18.1 2.6 0.0 0.0 0.8 0.2 2.3 0.0 0.6 0.0 0.3 13.6 0.0 0.9 0.0 3.8 1.7 1.1 0.1 0.0 0.9 0.1 0.3 0.0 0.0 0.0 ALPK3 "KIAA1330, MAK, Midori" ENSG00000136383 "Alpha kinase 3" Q96L96 15 84817356-84873479 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 62.7;skeletal muscle: 195.8;tongue: 59.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 64.1;Exocrine glandular cells: 20.5;Skeletal myocytes: 51.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.3;HDLM-2: 10.7;HUVEC TERT2: 15.5;LHCN-M2: 21.2;NTERA-2: 12.9;RH-30: 37.7;THP-1: 9.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA026558 Uncertain Approved Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "HPA026558: AB_1844774" "unprognostic (2.69e-2)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (4.61e-2)" "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.44e-3)" "unprognostic (1.42e-1)" "unprognostic (1.68e-2)" "unprognostic (1.82e-1)" "unprognostic (1.74e-3)" "unprognostic (1.23e-1)" "prognostic favorable (3.95e-7)" "unprognostic (1.76e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (4.87e-2)" 12.5 9.6 1.2 0.9 1.6 0.1 4.4 1.0 2.2 2.2 9.3 7.5 0.6 1.5 5.4 3.0 1.7 1.8 62.7 1.3 3.8 13.5 5.9 5.5 0.6 2.2 3.4 0.8 7.7 11.2 26.1 2.5 4.5 2.4 0.8 2.5 2.6 1.3 195.8 1.0 2.1 3.1 1.6 0.5 5.2 0.9 3.9 0.6 3.6 59.1 0.4 3.6 1.4 1.1 1.8 0.1 0.1 0.2 0.3 0.1 14.3 0.0 0.0 0.0 0.1 0.1 6.3 0.0 0.4 0.0 0.1 1.1 0.0 0.0 0.1 10.7 1.7 1.8 0.3 0.0 0.2 0.0 0.1 1.3 0.2 0.0 0.0 0.1 15.5 0.1 0.0 0.1 21.2 0.9 0.0 0.2 12.9 0.3 0.1 0.0 37.7 0.2 0.0 4.0 0.0 0.2 0.0 2.0 0.1 1.9 0.1 9.6 0.3 0.1 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 1.0 2.2 1.3 3.8 2.2 3.4 4.5 1.6 3.9 1.1 3.3 6.4 2.7 2.6 0.2 0.9 0.1 0.6 1.2 4.1 1.3 0.8 64.1 17.2 2.4 9.2 16.7 0.3 0.2 0.5 0.0 2.9 0.3 11.5 1.0 8.7 9.1 0.0 3.0 20.5 0.7 3.8 0.5 8.9 1.3 8.7 1.8 1.7 10.2 0.0 3.4 0.3 0.0 0.3 12.0 0.0 0.0 5.2 3.6 9.4 4.7 1.0 1.0 0.5 0.3 10.4 1.2 0.0 1.5 0.7 0.1 2.2 4.2 3.4 0.0 51.9 8.4 0.5 3.2 0.2 0.1 0.7 0.5 0.2 0.3 1.6 AMT "GCST, NKH" ENSG00000145020 Aminomethyltransferase P48728 3 49416778-49422685 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 42.4;Proximal enterocytes: 33.3;Undifferentiated cells: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 17.1;Hep G2: 47.5;NTERA-2: 8.0;SH-SY5Y: 14.9;SuSa: 9.0" HPA005566 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA005566: AB_1844811" "unprognostic (2.10e-2)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (9.14e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (2.17e-3)" "unprognostic (1.94e-1)" "unprognostic (3.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.90e-8)" "unprognostic (4.40e-1)" "unprognostic (1.91e-1)" "unprognostic (3.60e-1)" "unprognostic (1.98e-3)" 4.7 12.8 9.8 1.2 10.3 8.8 5.6 10.7 11.7 11.8 13.1 12.2 13.8 6.8 8.2 3.5 10.1 5.8 21.6 9.4 9.6 23.2 49.1 5.4 2.1 9.8 10.2 12.5 19.5 14.2 11.9 2.3 9.8 11.3 11.8 6.5 10.6 8.5 3.1 4.8 12.1 3.7 9.9 6.3 11.1 3.0 10.0 3.8 5.8 4.2 1.5 8.0 6.4 9.9 0.1 0.7 1.4 0.4 0.6 0.0 17.1 0.0 0.4 0.1 0.3 0.5 0.6 0.0 0.2 0.4 0.0 0.3 0.1 0.7 0.1 0.3 0.0 0.0 0.5 47.5 1.8 0.0 0.0 0.6 1.8 0.0 0.7 1.3 0.6 0.2 0.0 0.0 0.2 0.4 0.1 0.1 8.0 0.0 0.2 0.0 0.5 1.0 0.8 0.4 0.0 14.9 0.2 0.0 1.1 9.0 0.1 0.3 0.6 0.1 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 3.2 0.0 1.7 0.0 0.5 0.0 0.0 4.2 0.2 1.2 0.9 0.1 7.9 0.5 0.3 0.0 1.3 9.8 10.3 10.7 11.7 9.4 9.6 9.8 10.2 9.8 9.9 10.0 9.9 1.2 3.2 9.2 11.4 3.6 2.8 12.1 3.1 3.4 17.4 1.2 1.3 21.8 14.3 6.3 0.0 20.9 25.6 1.4 13.8 0.0 0.8 2.5 0.7 1.6 3.2 12.7 8.8 8.7 0.7 8.8 4.5 15.8 1.0 7.6 2.0 3.9 42.4 5.0 8.4 8.5 18.4 2.0 3.8 2.9 1.6 10.5 2.6 5.4 7.5 1.8 26.0 7.2 6.0 6.6 0.6 18.9 6.4 1.1 6.7 33.3 1.1 6.6 19.3 6.6 5.2 3.1 1.9 0.3 2.2 2.7 10.3 3.8 1.0 31.6 10.9 ANAPC15 "APC15, C11orf51, DKFZP564M082, HSPC020" ENSG00000110200 "Anaphase promoting complex subunit 15" P60006 11 72106378-72112780 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036596 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA036596: AB_10671961" "unprognostic (1.17e-1)" "unprognostic (5.83e-2)" "unprognostic (4.23e-2)" "unprognostic (3.05e-2)" "unprognostic (1.86e-2)" "unprognostic (2.09e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (9.18e-2)" "unprognostic (3.35e-2)" "prognostic favorable (2.55e-4)" "unprognostic (9.34e-3)" "unprognostic (1.76e-1)" "unprognostic (1.26e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.77e-1)" "unprognostic (9.08e-2)" 28.9 44.2 47.0 30.0 47.5 95.9 30.0 47.8 61.1 24.3 45.8 67.1 30.7 43.4 38.3 53.2 30.4 18.3 62.2 47.2 47.7 48.8 44.0 30.0 43.5 46.4 46.8 22.4 39.2 25.4 32.8 19.2 47.2 52.0 40.6 42.8 39.9 38.8 95.2 39.6 40.1 31.9 46.4 41.2 46.5 72.0 46.3 72.6 44.7 64.3 44.3 41.6 29.5 49.0 74.0 109.4 87.5 55.8 25.5 41.2 41.4 77.1 70.1 121.3 80.2 128.8 78.4 98.8 72.9 110.3 59.0 122.6 133.4 144.0 113.9 64.0 63.3 113.1 124.9 84.5 30.2 110.8 101.3 43.2 56.2 68.9 91.6 45.4 80.7 136.7 83.3 66.6 80.0 127.2 214.5 102.9 70.9 155.3 62.3 89.6 217.4 67.2 106.1 50.5 61.9 53.8 79.0 76.5 127.0 46.8 89.6 58.6 73.4 55.5 72.9 110.5 82.8 68.0 71.5 125.3 34.0 87.8 31.7 29.7 168.5 136.3 73.3 114.2 78.0 94.5 93.4 86.3 148.8 71.4 110.9 101.5 68.4 72.4 107.4 119.1 153.0 124.1 47.0 47.5 47.8 61.1 47.2 47.7 46.4 46.8 47.2 46.4 46.3 49.0 20.1 16.0 16.5 2.9 36.1 41.8 71.2 83.5 44.3 32.9 43.2 55.6 3.9 12.8 50.6 23.9 27.1 84.7 40.5 82.9 123.3 49.4 15.4 38.8 21.3 22.8 49.6 34.1 7.1 102.7 78.8 18.3 36.7 27.8 30.4 27.2 15.0 44.1 82.8 13.5 7.3 66.2 61.1 48.5 47.5 13.4 6.8 48.0 26.6 1.0 58.8 44.1 36.0 5.5 5.2 53.1 61.4 23.0 47.1 43.8 56.2 123.6 45.6 43.3 19.7 16.0 35.3 115.9 139.9 53.8 41.1 46.7 41.1 32.3 71.5 61.7 ANAPC16 "APC16, bA570G20.3, C10orf104, CENP-27, FLJ33728" ENSG00000166295 "Anaphase promoting complex subunit 16" Q96DE5 10 72216000-72235860 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 93.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037815 Approved Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA037815: AB_10672288" "unprognostic (2.87e-1)" "unprognostic (4.35e-3)" "unprognostic (2.01e-2)" "unprognostic (7.12e-3)" "unprognostic (2.16e-1)" "unprognostic (6.20e-3)" "unprognostic (1.51e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (3.10e-2)" "unprognostic (1.90e-2)" "unprognostic (2.11e-1)" "unprognostic (2.75e-3)" "unprognostic (7.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-3)" 20.5 25.2 12.4 15.0 13.4 14.1 21.9 16.6 15.2 19.7 15.5 23.6 15.7 18.2 22.3 14.9 23.5 12.6 43.6 12.5 12.8 24.2 27.2 18.9 25.4 13.6 12.8 24.3 33.7 33.1 15.9 11.9 13.4 21.5 17.9 20.6 32.3 21.8 62.7 15.0 19.6 17.8 12.4 22.7 25.8 8.4 13.1 32.3 23.5 43.2 25.7 19.5 15.1 14.6 24.9 12.1 12.1 14.3 33.0 15.7 9.3 8.5 17.3 11.7 11.0 14.6 31.1 24.3 13.6 12.7 14.1 19.0 10.9 21.9 11.0 29.0 18.0 12.5 10.6 14.4 39.6 21.0 14.7 20.5 93.9 10.6 34.8 25.8 14.3 35.1 18.4 28.1 13.6 15.0 17.9 21.1 9.3 18.2 6.8 10.2 10.8 24.2 29.4 10.4 17.4 16.0 14.8 37.9 29.5 15.2 12.2 21.9 18.6 5.9 13.8 9.5 13.1 28.6 26.8 25.1 16.4 40.3 7.0 41.1 21.5 38.8 31.4 23.1 35.2 60.5 35.2 31.3 18.1 66.1 48.6 38.6 19.7 34.4 24.9 45.7 34.7 36.3 12.4 13.4 16.6 15.2 12.5 12.8 13.6 12.8 13.4 12.4 13.1 14.6 191.0 157.0 209.5 41.8 303.7 111.7 246.7 322.0 150.8 81.0 288.6 316.5 435.4 280.2 234.9 222.5 37.5 198.4 240.1 166.8 684.8 239.8 91.9 188.9 98.9 179.8 161.8 155.0 47.8 291.9 191.2 142.0 108.1 145.9 202.0 110.1 203.1 481.3 226.5 33.7 57.2 258.0 254.3 310.0 111.9 53.4 233.6 160.4 193.9 36.5 322.4 192.4 363.5 43.2 75.9 196.9 239.9 250.1 208.2 218.1 262.6 548.7 217.0 144.5 230.1 162.0 219.9 158.7 126.2 189.9 140.9 149.3 268.6 145.6 214.1 240.9 ANKRD9 ENSG00000156381 "Ankyrin repeat domain 9" Q96BM1 14 102501767-102509799 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 112.0;skeletal muscle: 154.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.8;Early spermatids: 161.0;Erythroid cells: 146.5;Proximal enterocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055985 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055985: AB_2682996" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (3.05e-2)" "unprognostic (1.26e-2)" "unprognostic (7.76e-2)" "unprognostic (7.31e-3)" "unprognostic (6.78e-2)" "unprognostic (3.97e-2)" "unprognostic (3.35e-1)" "unprognostic (2.99e-1)" "unprognostic (3.68e-1)" "unprognostic (1.17e-1)" "prognostic favorable (1.17e-7)" "unprognostic (3.89e-1)" "unprognostic (4.74e-1)" "unprognostic (1.32e-2)" "unprognostic (1.15e-1)" 12.1 21.1 29.0 3.0 20.8 18.1 10.4 22.2 43.1 10.5 27.4 30.7 50.3 7.6 1.9 19.5 6.9 4.6 112.0 19.0 17.5 24.2 16.0 15.9 0.8 36.4 24.3 10.2 11.4 8.8 7.4 5.0 27.4 20.1 10.0 2.4 26.1 4.1 154.7 25.6 32.7 2.4 27.4 9.2 22.5 40.6 37.3 0.4 11.2 26.4 1.7 12.9 15.0 15.3 16.0 7.5 13.3 12.6 13.6 5.6 20.8 18.7 7.0 8.3 8.1 1.9 10.5 0.0 20.5 5.2 9.2 25.8 6.5 3.8 4.2 11.3 26.7 4.2 14.7 3.6 7.0 1.5 13.5 2.8 22.6 4.5 4.5 5.4 3.6 2.1 8.2 1.4 4.0 14.0 2.2 4.4 6.3 24.6 33.5 21.5 12.5 1.0 8.5 16.2 10.8 11.5 13.3 8.6 24.4 7.8 13.1 6.0 8.3 8.4 10.9 41.4 14.7 11.9 6.9 0.5 9.9 2.9 8.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 29.0 20.8 22.2 43.1 19.0 17.5 36.4 24.3 27.4 27.4 37.3 15.3 10.8 19.2 4.5 41.4 2.7 13.0 37.5 1.5 6.8 11.0 32.3 22.5 40.3 15.7 5.0 14.7 2.1 9.7 30.4 198.8 92.0 3.9 161.0 11.4 6.4 9.8 16.7 146.5 12.6 4.8 30.5 13.5 34.7 21.5 31.8 20.1 8.6 11.8 29.5 16.8 14.1 42.5 2.0 7.5 7.8 23.9 5.6 25.4 10.6 5.6 0.7 16.8 2.1 4.0 3.4 5.3 73.7 9.8 10.2 37.8 129.2 16.7 1.1 7.7 13.1 26.8 10.8 6.6 6.7 14.1 20.2 18.3 9.3 18.3 56.7 54.8 ANO5 "GDD1, LGMD2L, TMEM16E" ENSG00000171714 "Anoctamin 5" Q75V66 11 21799934-22283357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 24.9;parathyroid gland: 17.0;skeletal muscle: 65.5;tongue: 50.4" "Group enriched" "Detected in many" 7 "Astrocytes: 67.9;Cardiomyocytes: 86.2;Excitatory neurons: 166.6;Inhibitory neurons: 136.4;Oligodendrocyte precursor cells: 81.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.9;HAP1: 5.0;HEK 293: 6.6;NTERA-2: 3.5;RPTEC TERT1: 3.2;U-266/84: 3.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058857 Uncertain NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058857: AB_2683835" "unprognostic (5.25e-3)" "unprognostic (1.36e-3)" "unprognostic (2.43e-1)" "unprognostic (7.67e-3)" "unprognostic (3.50e-2)" "unprognostic (5.85e-2)" "unprognostic (8.17e-3)" "unprognostic (2.30e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.54e-4)" "unprognostic (8.55e-2)" "prognostic favorable (2.50e-7)" "unprognostic (3.65e-3)" "unprognostic (2.84e-1)" "unprognostic (2.77e-4)" "unprognostic (7.94e-2)" 0.9 4.5 1.9 0.8 3.0 0.0 0.7 0.1 8.9 1.6 3.0 2.6 3.3 1.5 1.3 2.0 0.8 1.7 24.9 4.0 2.2 3.6 2.1 1.2 0.2 2.7 2.1 0.5 3.9 17.0 3.4 0.0 2.2 4.2 3.3 2.1 2.6 4.1 65.5 0.1 2.5 2.7 0.4 0.7 3.0 1.8 2.4 0.2 4.7 50.4 0.3 2.0 0.3 3.4 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.3 1.4 2.5 0.0 0.0 0.0 0.0 3.5 2.6 0.0 0.0 0.0 0.0 3.2 0.1 2.7 2.6 0.0 0.0 0.0 2.1 2.1 1.9 0.0 0.0 1.9 0.0 0.0 2.0 3.7 0.0 2.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.0 0.1 8.9 4.0 2.2 2.7 2.1 2.2 0.4 2.4 3.4 0.4 0.0 5.9 67.9 0.6 0.3 0.3 0.0 0.0 6.7 2.2 0.6 86.2 1.5 0.0 1.8 0.0 0.1 0.0 7.8 1.9 1.3 5.8 0.4 0.2 3.2 5.4 0.4 166.6 2.7 0.0 3.0 1.5 0.3 0.0 3.0 2.5 5.1 0.5 1.7 136.4 7.1 0.0 0.6 1.4 2.9 0.0 1.6 1.8 14.0 1.9 2.8 0.0 81.4 4.2 1.0 4.4 1.2 0.0 1.4 2.7 3.3 0.7 0.8 0.0 8.1 2.4 11.0 0.9 0.1 0.1 0.0 0.2 1.6 4.6 0.2 APOBEC2 "ARCD1, ARP1" ENSG00000124701 "Apolipoprotein B mRNA editing enzyme catalytic subunit 2" Q9Y235 6 41053202-41064891 "Enzymes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 203.7;skeletal muscle: 853.2;tongue: 288.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Cardiomyocytes: 103.5;Early spermatids: 25.7;Exocrine glandular cells: 21.8;Extravillous trophoblasts: 18.1;Late spermatids: 25.1;Skeletal myocytes: 36.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.7;pancreatic cancer: 4.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "CACO-2: 2.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA014252, HPA017957" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "HPA014252: AB_1844932, HPA017957: AB_1844933" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-1)" "unprognostic (2.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (7.22e-2)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-1)" "unprognostic (2.01e-2)" "unprognostic (7.02e-2)" "unprognostic (3.69e-1)" "unprognostic (1.31e-3)" "unprognostic (2.19e-2)" 0.2 0.8 0.3 0.3 0.9 1.1 0.3 0.4 0.7 0.0 0.2 0.8 1.4 0.1 0.0 12.0 0.1 0.1 203.7 0.2 0.4 0.4 0.1 0.5 0.3 1.0 0.6 0.1 12.7 0.0 0.1 0.7 0.8 7.7 0.1 5.7 12.7 0.0 853.2 1.1 1.2 2.1 0.5 0.2 12.6 2.7 0.7 10.9 0.3 288.0 0.0 0.3 0.1 1.7 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.7 0.1 0.3 0.1 0.1 0.0 0.8 0.6 1.3 1.6 0.5 1.4 2.1 1.5 1.7 0.4 1.9 1.6 1.8 0.6 0.6 0.9 2.2 1.6 0.1 0.3 0.9 0.4 0.7 0.2 0.4 1.0 0.6 0.8 0.5 0.7 1.7 0.0 0.0 0.0 1.0 0.0 0.3 0.7 1.0 0.0 15.8 0.0 0.0 103.5 0.0 0.0 0.0 2.1 1.6 0.1 0.0 0.0 8.0 25.7 0.0 0.0 1.2 0.0 0.0 0.5 21.8 18.1 2.3 8.6 0.1 0.0 0.0 0.0 0.0 0.4 1.7 0.5 0.1 0.0 0.3 0.3 25.1 0.3 0.1 1.8 0.0 0.0 0.9 0.0 2.0 3.7 2.2 0.0 0.0 0.0 0.0 0.5 2.0 0.0 3.1 0.0 36.7 2.0 1.1 0.2 0.0 0.0 1.4 0.1 0.0 0.0 0.0 APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" 9.0 23.7 55.8 9.0 58.0 7.9 13.3 58.1 76.3 13.1 67.8 17.3 14.4 10.6 19.6 12.6 20.8 9.3 65.1 57.9 58.4 46.5 18.2 8.6 11.7 58.8 57.0 9.4 14.2 62.0 29.2 10.9 57.3 13.7 18.8 52.8 19.7 15.0 45.9 7.7 12.0 12.0 57.0 8.4 17.7 16.8 56.8 14.0 20.3 73.2 11.6 11.2 8.1 57.1 36.5 32.7 53.9 37.8 8.8 19.9 8.3 17.9 21.9 37.4 38.8 19.3 17.0 31.5 21.9 16.5 48.5 29.3 68.5 35.7 41.2 33.4 48.7 15.9 28.6 31.1 20.8 40.9 17.1 22.2 20.7 41.2 30.4 20.1 26.6 38.8 22.9 33.2 35.1 34.6 41.2 43.0 49.2 47.5 52.7 31.5 26.6 75.6 74.1 18.4 36.4 26.5 39.0 36.7 39.7 52.4 63.6 17.9 6.5 23.9 14.6 86.6 27.9 26.3 50.5 28.7 38.5 19.8 35.8 14.8 4.8 1.4 12.6 15.9 16.6 10.8 13.7 12.5 14.0 10.2 10.9 10.7 3.0 10.3 16.0 16.6 14.0 7.7 55.8 58.0 58.1 76.3 57.9 58.4 58.8 57.0 57.3 57.0 56.8 57.1 7.4 16.0 11.5 61.7 11.8 14.0 17.0 74.3 11.4 20.4 14.3 17.0 61.8 21.5 28.3 23.9 14.6 17.2 11.3 12.8 180.0 28.4 25.9 56.0 13.0 10.1 7.2 20.8 61.4 16.0 8.9 11.7 13.3 24.4 3.8 14.2 7.9 13.9 22.7 20.2 76.5 17.0 44.7 14.6 12.0 15.7 11.5 9.9 28.4 74.0 34.2 50.0 8.2 43.7 76.5 10.2 20.0 15.8 14.8 14.1 24.0 80.6 106.9 32.4 6.6 10.8 22.3 26.1 53.2 18.9 7.0 12.4 9.5 17.0 22.3 16.8 ARMH3 "C10orf76, FLJ13114" ENSG00000120029 "Armadillo like helical domain containing 3" Q5T2E6 10 101845599-102056193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.2;dendritic cells: 10.5;Extravillous trophoblasts: 14.8;Granulosa cells: 11.5;Hofbauer cells: 12.6;Syncytiotrophoblasts: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050913, HPA053580" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA050913: AB_2681270, HPA053580: AB_2682198" "unprognostic (5.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "unprognostic (3.41e-2)" "unprognostic (9.41e-2)" "unprognostic (9.55e-2)" "unprognostic (5.28e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (6.03e-3)" "unprognostic (1.40e-3)" "unprognostic (2.76e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-1)" "unprognostic (2.48e-1)" "unprognostic (3.85e-1)" "unprognostic (4.87e-2)" 10.4 9.1 5.9 12.0 7.6 21.8 9.9 10.2 7.3 11.2 8.0 12.5 12.8 10.5 9.4 14.3 10.5 9.2 16.6 5.7 7.3 10.0 12.0 11.8 12.7 7.1 8.2 11.2 10.1 16.4 7.9 11.0 6.1 10.8 13.2 16.3 9.5 10.5 19.7 12.2 12.2 12.9 6.0 13.6 10.3 8.9 6.7 13.1 10.0 19.8 13.3 10.8 10.1 7.9 23.2 17.7 15.5 19.1 12.9 17.3 13.9 20.3 24.0 20.0 16.9 12.2 18.6 17.0 13.5 22.9 14.5 17.7 20.4 22.4 18.3 17.9 18.9 30.3 15.9 14.6 15.2 21.3 26.4 16.0 17.7 22.6 19.9 23.4 15.3 15.3 0.9 15.9 16.6 14.4 16.5 13.8 8.5 18.8 11.6 16.0 28.1 11.0 16.4 18.6 7.3 12.1 15.8 10.9 21.0 15.8 28.8 12.4 15.1 10.5 17.1 9.8 14.7 15.4 17.0 17.1 16.9 23.7 7.9 19.4 7.3 7.4 5.9 8.7 5.5 6.1 6.2 4.5 7.7 7.0 4.8 4.9 1.9 5.2 10.7 7.4 6.0 4.7 5.9 7.6 10.2 7.3 5.7 7.3 7.1 8.2 6.1 6.0 6.7 7.9 8.8 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 7.4 6.0 0.0 0.0 0.0 0.0 0.0 11.2 10.5 0.0 1.9 7.8 0.0 6.9 6.8 1.9 0.0 0.0 0.0 9.7 14.8 2.7 0.0 7.7 0.0 11.5 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.9 0.0 0.0 2.2 0.0 0.0 7.6 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 16.3 3.9 5.7 0.0 0.0 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ASB11 DKFZp779E2460 ENSG00000165192 "Ankyrin repeat and SOCS box containing 11" Q8WXH4 X 15281697-15315640 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "heart muscle: 33.4;skeletal muscle: 114.7;tongue: 61.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.7;Ionocytes: 6.1;Melanocytes: 7.2" "Cancer enriched" "Detected in single" 20 "melanoma: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (5.89e-3)" "unprognostic (1.04e-1)" "unprognostic (9.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.42e-2)" "unprognostic (5.54e-2)" "unprognostic (2.04e-2)" "unprognostic (2.36e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (6.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.7 0.0 114.7 0.8 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 61.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.6 0.2 0.0 0.2 0.2 0.1 8.7 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.4 0.1 0.3 1.7 0.3 0.1 6.1 0.3 0.8 0.3 0.3 0.2 7.2 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.3 0.0 1.9 0.2 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.4 ASB14 DKFZp313L0121 ENSG00000239388 "Ankyrin repeat and SOCS box containing 14" A6NK59 3 57268342-57292685 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "skeletal muscle: 28.1;tongue: 18.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Cardiomyocytes: 8.2;Excitatory neurons: 4.8;Inhibitory neurons: 4.3;Oligodendrocyte precursor cells: 5.5;Oligodendrocytes: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.14e-3)" "unprognostic (1.85e-1)" "unprognostic (3.64e-1)" "unprognostic (7.14e-2)" "unprognostic (9.76e-2)" "unprognostic (1.22e-1)" "unprognostic (2.37e-3)" "unprognostic (1.81e-4)" "unprognostic (1.11e-1)" "unprognostic (1.37e-1)" "unprognostic (1.24e-2)" "unprognostic (1.45e-2)" "unprognostic (6.69e-2)" "unprognostic (6.87e-2)" "unprognostic (9.68e-2)" "unprognostic (5.93e-2)" "unprognostic (5.71e-3)" 0.6 0.3 0.1 0.5 0.3 1.9 0.6 1.4 0.4 0.6 0.4 0.4 0.2 0.3 0.0 0.4 0.5 0.2 3.9 0.1 0.2 0.3 0.3 0.6 0.7 0.6 0.3 0.5 1.5 0.0 0.4 0.1 0.4 0.3 0.0 1.6 0.7 0.0 28.1 0.8 0.5 0.0 0.4 0.6 0.5 0.3 0.3 0.0 0.4 18.0 0.0 0.4 0.6 0.5 0.2 0.1 0.1 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.9 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.2 0.4 1.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.6 0.0 0.1 0.7 0.9 0.1 0.1 0.3 0.1 0.2 0.2 0.0 0.6 0.2 0.7 0.1 0.3 0.1 0.4 0.3 0.1 0.3 0.1 0.2 0.7 0.6 0.4 0.6 0.4 0.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 1.4 0.4 0.1 0.2 0.6 0.3 0.4 0.4 0.3 0.5 0.1 3.2 0.5 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.2 0.2 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.5 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.2 0.0 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 ASB16 FLJ30165 ENSG00000161664 "Ankyrin repeat and SOCS box containing 16" Q96NS5 17 44170447-44179084 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 67.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.4;Horizontal cells: 1.7;Inhibitory neurons: 1.6;NK-cells: 2.1;Oligodendrocyte precursor cells: 1.5;Rod photoreceptor cells: 2.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 9.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066834 Approved Approved "Focal adhesion sites" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" "Focal adhesion sites" "HPA066834: AB_2685732" "unprognostic (2.72e-2)" "unprognostic (8.47e-3)" "unprognostic (4.24e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-1)" "unprognostic (5.95e-2)" "unprognostic (2.45e-2)" "unprognostic (2.31e-3)" "unprognostic (1.03e-2)" "unprognostic (6.13e-2)" "unprognostic (7.23e-4)" "unprognostic (5.84e-2)" "unprognostic (3.97e-2)" "unprognostic (8.53e-3)" "unprognostic (7.33e-2)" "unprognostic (2.20e-1)" "unprognostic (1.07e-3)" 0.8 1.0 0.8 2.3 0.9 2.2 0.6 9.8 1.2 1.1 0.0 1.5 2.1 1.9 0.0 1.0 1.4 1.1 4.6 0.5 0.3 1.1 0.6 1.1 3.3 1.5 1.8 1.7 3.6 1.6 1.9 0.6 1.6 1.6 0.0 2.3 2.0 0.2 67.7 3.2 2.1 0.6 0.1 3.1 2.0 1.0 1.1 0.0 1.2 13.1 0.0 1.2 0.8 1.6 2.1 3.9 4.6 4.2 0.0 0.0 3.7 4.2 0.0 0.0 0.0 3.0 2.3 3.2 2.5 0.0 1.0 4.9 0.0 0.0 0.0 5.0 6.8 2.0 8.0 3.4 0.0 2.1 6.2 0.0 0.0 0.0 0.0 1.2 0.0 4.7 3.7 7.6 0.0 3.5 2.6 4.0 1.3 0.7 4.5 8.0 4.4 4.8 0.0 3.1 4.6 2.6 2.0 0.6 0.7 1.3 6.0 2.0 2.1 5.7 5.1 3.5 2.7 11.8 6.2 2.9 1.3 3.0 3.8 2.3 1.3 5.8 1.7 1.2 2.0 2.5 1.8 1.6 0.7 1.9 2.3 1.5 4.1 2.6 1.1 1.6 1.9 1.6 0.8 0.9 9.8 1.2 0.5 0.3 1.5 1.8 1.6 0.1 1.1 1.6 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 1.4 0.2 0.1 0.1 0.0 0.2 0.0 0.2 0.7 0.0 0.1 1.7 1.6 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.0 0.0 0.7 2.1 1.5 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.6 0.2 0.3 0.4 0.3 0.0 0.0 0.2 0.3 0.1 0.1 ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 522.2;tongue: 157.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.1;Early spermatids: 26.4;Late spermatids: 29.9;Skeletal myocytes: 27.6;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "eosinophil: 50.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 50.8" "Cell line enhanced" "Detected in some" "Karpas-707: 12.8;RPMI-8226: 12.4;SK-MEL-30: 5.9;U-266/70: 42.1;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: AB_1078224" "unprognostic (5.65e-4)" "unprognostic (8.19e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.62e-6)" "unprognostic (4.11e-2)" "unprognostic (1.61e-1)" "unprognostic (5.29e-2)" "unprognostic (1.05e-3)" "unprognostic (4.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-7)" "unprognostic (2.51e-3)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.27e-1)" 2.9 0.8 0.8 5.6 2.1 0.5 1.5 0.0 1.9 12.0 0.0 66.5 4.0 31.6 0.3 4.0 26.6 0.5 78.5 0.6 0.0 0.5 0.5 3.0 7.4 0.1 0.0 2.9 0.3 0.2 0.2 0.2 0.3 14.4 0.4 0.0 6.6 0.9 522.2 2.3 18.3 1.6 0.0 4.2 17.2 0.4 0.3 0.4 1.2 157.6 3.2 30.4 8.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.4 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 12.4 0.0 0.2 0.1 0.0 0.0 0.0 5.9 0.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 42.1 8.6 1.7 0.5 2.6 0.5 0.0 0.2 50.8 1.9 2.7 0.3 1.9 1.7 3.8 4.2 0.4 0.2 0.5 0.1 0.0 7.8 0.4 2.3 1.3 0.8 2.1 0.0 1.9 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.0 0.3 3.3 0.4 0.1 8.4 0.0 0.2 0.2 0.9 51.1 0.0 2.9 0.0 0.0 0.1 3.0 0.0 0.0 1.4 26.4 1.7 0.3 0.5 0.0 2.7 4.7 0.0 0.5 1.9 1.1 2.5 0.0 0.0 0.0 0.0 0.6 0.0 1.9 0.0 0.0 0.0 0.3 29.9 0.3 5.3 1.8 1.9 5.8 0.8 2.1 0.0 0.7 0.2 0.0 0.4 10.7 0.1 0.0 0.0 0.4 1.1 0.0 27.6 5.0 0.8 8.4 0.1 0.1 2.9 14.5 0.1 0.1 0.3 ASB4 ASB-4 ENSG00000005981 "Ankyrin repeat and SOCS box containing 4" Q9Y574 7 95478444-95540233 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 47.1;skeletal muscle: 34.2" "Cell type enhanced" "Detected in some" "Astrocytes: 7.2;Cardiomyocytes: 3.2;Early spermatids: 2.3;Late spermatids: 2.0;Respiratory ciliated cells: 2.0" "Cancer enhanced" "Detected in some" "stomach cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.9;Hep G2: 7.9;SCLC-21H: 4.7" "Group enriched" "Detected in many" 4 "basal ganglia: 9.5;hypothalamus: 31.7" "Region enriched" "Detected in single" 10 "midbrain: 4.3" HPA055240 Uncertain NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "HPA055240: AB_2682753" "unprognostic (1.41e-1)" "unprognostic (3.67e-1)" "unprognostic (1.88e-2)" "unprognostic (2.66e-1)" "unprognostic (3.71e-1)" "unprognostic (2.85e-3)" "unprognostic (1.17e-1)" "unprognostic (3.55e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "unprognostic (2.92e-2)" "unprognostic (4.24e-1)" "unprognostic (9.13e-7)" "unprognostic (1.71e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-1)" "unprognostic (7.23e-2)" 0.1 47.1 1.8 0.2 2.3 0.6 0.4 2.3 2.1 0.1 1.5 0.1 0.3 0.1 0.2 0.3 0.3 0.2 1.9 1.8 2.4 0.2 1.5 0.6 0.3 2.5 3.8 0.2 0.7 0.0 8.4 2.1 2.6 0.2 0.1 1.3 0.6 0.2 34.2 0.3 0.4 0.1 1.8 0.3 0.6 0.3 2.2 0.2 0.3 10.5 0.1 0.0 0.0 2.8 0.2 4.9 0.2 1.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.8 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.7 0.1 0.1 0.0 0.1 0.1 4.7 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.4 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.3 2.3 2.1 1.8 2.4 2.5 3.8 2.6 1.8 2.2 2.8 0.1 0.0 0.5 7.2 0.0 0.1 0.1 0.5 0.0 0.0 0.4 0.1 3.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 2.0 0.6 0.0 0.0 1.0 0.0 0.0 1.0 1.0 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.4 2.0 0.0 0.0 0.7 0.1 0.9 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.1 ASIC3 "ACCN3, DRASIC, TNaC1" ENSG00000213199 "Acid sensing ion channel subunit 3" Q9UHC3 7 151048292-151052756 "Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 12.5;Early spermatids: 15.6;Granulosa cells: 14.8;Late spermatids: 61.0;Spermatocytes: 10.3" "Group enriched" "Detected in many" 4 "glioma: 3.1;testis cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 16.7;U-266/84: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049155, HPA054805" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA049155: AB_2680657, HPA054805: AB_2732588" "unprognostic (8.71e-3)" "unprognostic (1.09e-1)" "unprognostic (1.92e-4)" "unprognostic (2.73e-1)" "unprognostic (7.06e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.42e-1)" "unprognostic (4.45e-2)" "unprognostic (8.64e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-12)" "unprognostic (1.49e-2)" "unprognostic (7.38e-2)" "unprognostic (1.65e-2)" "unprognostic (5.31e-3)" 2.8 2.1 8.2 0.3 9.0 0.6 2.7 11.7 10.9 13.3 6.7 7.9 1.1 7.7 1.5 1.9 7.2 0.7 10.9 7.9 8.8 4.8 4.0 3.2 0.8 9.3 7.9 6.4 2.1 0.5 18.1 0.6 10.3 5.3 0.6 8.7 1.6 0.4 6.0 2.9 4.1 0.8 7.0 2.8 3.8 19.9 8.6 0.6 4.1 0.9 0.7 3.1 4.3 11.5 1.5 4.0 1.7 2.7 3.7 0.0 7.4 0.4 0.2 0.3 0.5 0.8 1.9 0.9 0.4 0.2 1.8 2.4 1.0 0.0 0.7 8.9 4.5 1.7 3.4 0.0 0.0 0.1 3.9 0.9 0.7 0.2 0.0 2.9 0.1 1.1 4.2 6.8 0.5 6.3 0.3 0.4 1.8 0.1 3.3 3.1 1.7 0.5 0.3 1.4 2.3 8.2 0.6 0.5 4.3 4.9 1.8 0.4 0.1 1.4 2.1 4.3 1.1 16.7 10.2 0.1 2.3 5.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 9.0 11.7 10.9 7.9 8.8 9.3 7.9 10.3 7.0 8.6 11.5 0.4 0.0 0.5 2.9 0.5 0.6 0.0 0.2 0.0 9.7 0.6 0.6 2.1 0.0 0.2 0.0 12.5 0.2 0.3 0.6 0.0 0.2 15.6 0.9 1.1 0.3 0.0 0.0 3.4 0.4 0.2 0.3 0.5 0.8 8.9 14.8 0.0 0.9 0.6 6.7 4.2 0.1 0.0 0.6 0.9 61.0 1.5 0.4 0.0 0.0 0.6 1.6 0.0 1.5 5.1 0.4 0.0 1.9 0.1 0.3 0.2 0.2 0.6 4.9 0.0 0.7 0.4 10.3 5.6 0.0 0.9 0.7 0.3 0.2 0.2 0.2 ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 14.8;heart muscle: 28.0;ovary: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.4;dendritic cells: 44.1;Hofbauer cells: 15.1;Leydig cells: 12.5;Peritubular cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 356 "plasmacytoid DC: 134.8" "Lineage enriched" "Detected in single" 356 "dendritic cells: 134.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.2;HSkMC: 2.4;SK-MEL-30: 1.9;U-698: 1.9" "Not detected" "Not detected" HPA048636 Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" 1.4 0.6 0.2 0.0 0.5 0.3 2.4 0.1 0.4 4.2 0.0 0.5 0.0 2.0 14.8 0.1 4.0 0.1 28.0 0.1 0.1 0.9 1.3 0.3 0.4 0.2 0.1 41.7 0.1 0.0 0.6 0.2 0.6 1.5 0.0 0.3 0.7 0.2 0.9 5.7 0.8 0.0 0.0 0.3 0.3 1.5 0.2 0.2 0.3 1.2 0.5 0.5 1.1 0.3 0.0 1.1 0.4 0.4 0.2 0.7 0.1 0.1 0.0 0.0 0.0 3.2 0.0 1.2 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.7 0.3 0.5 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.1 0.0 0.7 0.6 0.9 0.0 0.3 0.2 1.7 0.0 0.1 0.6 0.3 0.3 1.4 0.0 0.1 0.2 0.2 0.0 0.2 1.9 0.5 0.3 0.2 0.3 0.5 0.5 0.0 0.3 0.4 0.4 1.9 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 134.8 0.0 0.6 0.2 0.5 0.1 0.4 0.1 0.1 0.2 0.1 0.6 0.0 0.2 0.3 0.4 0.0 0.6 1.3 0.8 2.5 0.0 0.0 0.0 0.0 0.3 0.5 27.4 0.0 0.0 0.0 0.0 0.2 44.1 0.0 1.9 0.0 1.1 0.3 9.2 1.2 0.0 0.0 2.1 0.0 0.2 5.6 0.0 0.4 0.0 0.2 2.5 5.8 15.1 0.0 1.8 0.0 0.0 0.8 7.0 1.7 12.5 2.1 1.8 1.0 0.3 0.0 0.0 2.5 2.5 0.1 0.0 10.5 0.0 0.1 0.0 8.3 0.0 0.0 6.6 0.1 0.6 1.7 1.9 0.2 3.1 0.8 0.6 1.0 0.0 0.1 ATP1A2 "FHM2, MHP2" ENSG00000018625 "ATPase Na+/K+ transporting subunit alpha 2" P50993 1 160115759-160143591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 515.9;skeletal muscle: 882.2;tongue: 478.0" "Cell type enhanced" "Detected in some" "Astrocytes: 515.8;Cardiomyocytes: 158.7;Microglial cells: 141.5;Muller glia cells: 73.0;Oligodendrocyte precursor cells: 94.0;Sertoli cells: 85.5" "Cancer enriched" "Detected in many" 18 "glioma: 91.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 51.9;HHSteC: 14.6;RH-30: 16.8;U-87 MG: 10.3" "Low region specificity" "Detected in all" CAB022230 Enhanced NA NA 170000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022230: " "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.83e-1)" "unprognostic (7.98e-2)" "unprognostic (2.16e-2)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.85e-2)" "unprognostic (8.63e-4)" "unprognostic (1.70e-2)" "unprognostic (9.40e-3)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (7.16e-2)" "unprognostic (5.32e-3)" 37.4 4.1 401.5 1.5 480.5 0.0 27.4 419.8 412.8 9.3 164.9 55.8 3.6 5.6 12.5 33.5 14.5 8.0 144.6 337.4 398.5 3.9 1.2 6.4 0.3 429.5 478.8 18.9 1.4 0.3 32.3 3.3 375.3 28.5 8.1 58.5 18.2 28.5 882.2 4.7 15.9 7.8 365.0 1.8 15.7 5.8 515.9 0.6 3.5 478.0 0.5 29.9 9.8 327.7 0.0 0.0 51.9 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 4.6 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 401.5 480.5 419.8 412.8 337.4 398.5 429.5 478.8 375.3 365.0 515.9 327.7 1.4 0.0 0.0 515.8 0.1 0.5 1.6 0.0 0.6 1.3 2.5 0.9 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 1.2 11.1 0.0 0.0 5.5 0.0 0.0 4.8 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 1.3 1.4 28.9 0.5 0.0 141.5 0.5 73.0 0.0 94.0 2.5 0.0 0.0 39.5 0.0 0.8 0.0 0.1 0.1 3.9 85.5 54.9 45.8 0.3 0.2 0.2 0.6 0.1 0.1 5.8 0.0 0.6 ATP5F1C "ATP5C, ATP5C1, ATP5CL1" ENSG00000165629 "ATP synthase F1 subunit gamma" P36542 10 7788147-7807815 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 895.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 517.1;Distal tubular cells: 890.2;Ductal cells: 453.9;Extravillous trophoblasts: 428.5;Hofbauer cells: 423.4;Proximal tubular cells: 938.6;Theca cells: 413.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060949 Approved NA NA 70000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" "HPA060949: AB_2684395" "unprognostic (1.81e-2)" "unprognostic (8.34e-2)" "unprognostic (3.87e-2)" "unprognostic (1.69e-2)" "unprognostic (2.17e-2)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (8.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.31e-3)" "unprognostic (1.62e-1)" "unprognostic (4.12e-1)" "prognostic favorable (9.26e-4)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (8.30e-2)" "unprognostic (4.08e-2)" 123.7 265.0 82.8 103.2 82.4 149.0 164.8 111.3 111.0 122.5 102.6 240.9 254.7 100.9 150.1 145.9 114.7 112.6 710.9 81.5 94.3 399.9 368.6 93.5 133.0 85.4 83.2 86.8 182.2 411.4 76.7 147.5 86.4 117.5 274.7 161.6 168.3 136.2 537.8 110.7 205.7 146.1 88.8 96.4 174.3 71.1 89.1 192.5 161.7 895.1 175.3 163.8 91.0 90.9 301.2 266.8 255.2 219.3 212.5 276.7 241.2 211.1 176.1 365.7 351.6 511.4 293.8 323.8 163.3 248.0 95.3 337.9 318.3 342.8 325.5 222.3 381.6 351.7 169.3 479.8 172.2 193.6 249.6 222.9 234.1 224.7 134.5 315.7 426.7 321.8 283.4 230.1 352.6 419.0 451.9 217.7 173.3 623.4 201.8 301.9 179.1 460.6 637.5 301.0 141.3 168.2 186.0 417.5 417.1 287.3 437.9 315.9 202.7 151.7 205.3 349.2 229.8 159.2 194.7 265.5 224.7 286.2 127.3 373.0 273.8 241.9 158.5 363.1 185.3 199.2 180.7 174.5 370.4 158.6 146.4 159.6 88.5 226.9 428.2 237.8 261.4 349.3 82.8 82.4 111.3 111.0 81.5 94.3 85.4 83.2 86.4 88.8 89.1 90.9 196.2 118.6 95.4 0.0 30.4 0.0 0.0 0.0 0.0 0.0 156.2 239.3 0.0 0.0 60.7 215.2 0.0 517.1 85.3 0.0 890.2 453.9 0.0 160.9 125.4 76.7 0.0 0.0 0.0 381.8 428.5 89.5 0.0 170.4 97.1 163.2 0.0 0.0 423.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.6 0.0 0.0 140.6 0.0 0.0 0.0 0.0 304.4 0.0 0.0 12.0 0.0 0.0 938.6 64.8 0.0 0.0 0.0 102.0 0.0 0.0 0.0 0.0 371.9 49.1 413.9 0.0 0.0 ATP5F1D ATP5D ENSG00000099624 "ATP synthase F1 subunit delta" P30049 19 1241746-1244825 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 806.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1702.2;Exocrine glandular cells: 566.6;Proximal tubular cells: 1831.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002865 Approved NA NA 160000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "HPA002865: AB_1078244" "unprognostic (4.80e-2)" "unprognostic (9.34e-2)" "unprognostic (7.77e-2)" "prognostic favorable (1.23e-4)" "unprognostic (1.64e-2)" "unprognostic (1.95e-1)" "unprognostic (4.63e-2)" "unprognostic (6.75e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-1)" "prognostic favorable (4.60e-4)" "unprognostic (6.95e-2)" "prognostic favorable (3.46e-5)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "unprognostic (3.74e-1)" "unprognostic (3.49e-2)" 129.0 213.4 74.1 16.2 71.1 31.7 114.0 93.7 110.0 108.1 74.1 196.9 65.6 104.3 8.4 198.2 102.7 11.6 575.2 75.3 80.2 256.0 365.3 87.2 21.6 99.2 74.8 106.8 251.9 34.7 138.4 14.4 95.2 128.1 17.5 6.9 133.9 29.4 806.2 164.9 143.4 11.3 73.1 113.1 200.5 58.6 94.7 15.8 134.4 123.1 15.9 132.5 120.6 74.3 109.6 58.3 17.9 67.2 20.4 29.9 67.0 73.1 30.4 42.4 30.8 60.6 28.4 109.7 46.2 25.6 10.7 92.8 19.9 76.0 5.5 76.5 196.6 66.5 69.6 81.2 50.4 117.4 95.5 59.5 20.6 17.1 23.6 23.9 45.3 72.2 98.4 85.3 19.9 164.8 127.7 84.9 77.6 69.5 284.8 121.1 47.2 233.1 72.3 70.6 71.3 82.1 48.6 76.5 132.4 7.1 57.2 54.8 66.6 38.4 52.9 93.0 61.4 216.0 118.4 41.7 70.8 54.6 59.3 203.0 283.7 128.0 211.9 287.7 255.9 284.2 267.4 233.8 321.3 287.1 242.4 227.7 99.2 246.5 237.6 349.2 287.1 251.6 74.1 71.1 93.7 110.0 75.3 80.2 99.2 74.8 95.2 73.1 94.7 74.3 265.3 16.0 25.4 0.0 101.9 0.0 0.0 0.0 0.0 0.0 402.1 533.8 0.0 0.0 9.3 380.7 0.0 393.5 155.1 0.0 1702.2 351.2 0.0 145.6 261.2 80.3 0.0 0.0 0.0 566.6 471.3 109.6 0.0 256.9 5.1 263.9 0.0 0.0 416.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.7 0.0 0.0 133.4 0.0 0.0 0.0 0.0 437.8 0.0 0.0 40.7 0.0 0.0 1831.8 5.1 0.0 0.0 0.0 145.9 0.0 0.0 0.0 0.0 341.2 82.8 469.2 0.0 0.0 ATP5F1E ATP5E ENSG00000124172 "ATP synthase F1 subunit epsilon" P56381 20 59025475-59032345 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 3414.2;Hofbauer cells: 2765.4;Proximal tubular cells: 4125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.73e-1)" "unprognostic (6.30e-2)" "unprognostic (8.16e-2)" "unprognostic (9.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.92e-3)" "unprognostic (7.88e-3)" "unprognostic (2.51e-1)" "unprognostic (5.01e-2)" "unprognostic (6.41e-2)" "unprognostic (4.35e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (3.98e-1)" "unprognostic (3.21e-1)" "unprognostic (1.67e-1)" "unprognostic (2.44e-2)" 81.4 88.3 92.2 98.5 94.5 125.6 62.3 95.3 135.8 49.3 95.7 77.2 80.1 51.2 25.3 77.0 45.2 13.9 162.8 92.7 95.7 128.5 80.2 69.3 69.8 94.2 94.0 42.1 44.9 52.9 104.8 34.0 94.4 50.6 33.1 42.8 62.7 23.7 240.1 42.8 78.9 25.6 95.4 93.5 69.5 47.7 93.7 64.7 64.1 107.0 40.0 63.4 55.5 97.1 150.0 49.6 98.1 90.0 94.0 87.2 65.2 155.9 60.6 102.2 66.0 156.3 143.5 81.1 184.7 82.7 159.6 141.5 70.3 123.7 67.0 66.7 76.4 271.4 107.2 136.5 86.4 193.2 234.6 95.0 105.3 62.5 77.8 99.8 76.9 107.6 103.6 113.8 59.4 144.4 247.8 299.1 32.9 220.4 203.4 120.2 138.3 156.8 107.5 83.0 98.0 146.6 261.6 273.9 328.4 83.5 182.5 312.8 264.3 208.3 222.0 138.9 213.7 180.2 245.9 238.1 201.5 117.9 117.1 613.1 420.6 757.3 237.5 463.8 224.9 351.4 285.8 268.7 356.0 291.7 227.8 259.4 713.9 243.1 470.7 601.7 393.3 781.7 92.2 94.5 95.3 135.8 92.7 95.7 94.2 94.0 94.4 95.4 93.7 97.1 1036.3 516.0 530.8 0.0 331.5 0.0 0.0 0.0 0.0 0.0 1042.4 1138.3 0.0 0.0 289.7 1121.9 0.0 705.8 812.6 0.0 3414.2 998.0 0.0 1145.2 1007.1 436.6 0.0 0.0 0.0 1202.6 956.9 341.7 0.0 1410.3 352.0 594.0 0.0 0.0 2765.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.4 0.0 0.0 1473.1 0.0 0.0 0.0 0.0 1427.7 0.0 0.0 132.5 0.0 0.0 4125.3 392.8 0.0 0.0 0.0 334.0 0.0 0.0 0.0 0.0 590.5 431.2 731.9 0.0 0.0 ATP5IF1 "ATPI, ATPIF1, ATPIP, IP, MGC1167, MGC8898" ENSG00000130770 "ATP synthase inhibitory factor subunit 1" Q9UII2 1 28236109-28246906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1035.0;Endometrial ciliated cells: 1524.2;Exocrine glandular cells: 672.1;Granulosa cells: 1030.6;Proximal tubular cells: 1502.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027999 Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA027999: AB_10600984" "unprognostic (2.80e-2)" "unprognostic (3.72e-2)" "unprognostic (2.95e-1)" "prognostic favorable (6.38e-8)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (6.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.40e-2)" "prognostic favorable (8.20e-4)" "unprognostic (5.94e-2)" "unprognostic (3.52e-1)" "unprognostic (6.15e-3)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (2.79e-1)" "unprognostic (1.48e-3)" 96.9 215.1 98.4 50.6 98.6 144.3 108.8 95.6 140.0 123.3 95.2 234.8 163.1 113.0 44.5 184.5 139.4 28.0 585.8 100.0 106.5 384.9 342.6 116.0 64.5 99.6 96.8 134.9 163.4 90.1 246.5 37.6 97.8 156.0 59.4 71.0 145.3 37.1 456.7 165.0 199.6 28.5 93.7 153.7 215.7 355.5 99.6 60.0 169.2 179.8 47.9 116.6 134.0 104.1 271.9 136.4 79.3 75.1 58.0 62.7 94.1 118.6 57.9 98.6 96.2 132.0 192.5 189.1 173.8 72.1 37.6 161.5 91.2 118.0 77.6 143.9 306.0 162.9 612.7 180.8 62.9 125.5 158.1 73.5 190.2 88.2 70.4 96.2 95.7 222.0 292.9 167.9 71.2 178.0 187.6 230.4 262.7 100.9 167.8 177.3 87.5 270.2 196.9 175.5 158.9 114.2 146.5 150.8 160.4 76.5 224.4 136.6 100.6 31.9 88.0 126.5 142.1 432.0 282.8 268.6 151.1 338.8 38.1 133.3 116.6 126.1 144.2 111.1 145.8 195.2 154.3 155.5 142.8 154.0 144.1 139.3 102.7 142.9 102.7 213.5 226.9 214.1 98.4 98.6 95.6 140.0 100.0 106.5 99.6 96.8 97.8 93.7 99.6 104.1 207.3 205.1 284.9 0.0 61.7 0.0 0.0 0.0 0.0 0.0 251.1 314.3 0.0 0.0 150.4 546.2 0.0 453.8 165.4 0.0 1035.0 396.6 0.0 1524.2 210.6 84.0 0.0 0.0 0.0 672.1 226.0 114.6 0.0 453.2 172.8 1030.6 0.0 0.0 372.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.6 0.0 0.0 123.0 0.0 0.0 0.0 0.0 550.3 0.0 0.0 30.3 0.0 0.0 1502.7 621.6 0.0 0.0 0.0 90.6 0.0 0.0 0.0 0.0 251.7 92.0 281.6 0.0 0.0 ATP5MC2 ATP5G2 ENSG00000135390 "ATP synthase membrane subunit c locus 2" Q06055 12 53632726-53677408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1335.2;Breast myoepithelial cells: 1873.6;Distal tubular cells: 1762.9;Hofbauer cells: 1076.1;Proximal tubular cells: 2061.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051469 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA051469: AB_2681496" "unprognostic (1.48e-1)" "unprognostic (1.06e-1)" "unprognostic (3.01e-1)" "unprognostic (3.37e-3)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (2.97e-3)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (3.45e-3)" "unprognostic (3.78e-2)" "unprognostic (5.71e-2)" "unprognostic (3.32e-3)" "unprognostic (3.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.42e-1)" "unprognostic (7.09e-2)" 250.6 297.8 487.0 240.0 510.5 445.5 485.5 498.2 574.6 338.4 492.0 444.0 383.6 279.1 463.7 340.5 533.7 296.1 759.6 475.9 499.0 437.4 469.4 243.6 406.4 509.5 488.1 487.2 499.1 503.0 18.9 265.3 507.8 322.2 551.7 275.9 483.0 284.9 1405.5 345.5 322.5 361.1 504.7 295.8 312.1 126.9 500.7 453.9 314.0 1447.2 540.2 365.6 15.2 519.7 325.4 684.8 701.3 640.3 478.0 1162.4 330.7 278.3 630.3 824.5 561.2 236.2 745.1 392.9 668.3 554.8 263.9 304.7 914.6 652.8 729.3 660.9 1096.7 1068.7 515.2 495.7 1034.1 819.7 508.5 1297.4 956.8 797.0 1315.9 1313.7 1078.7 468.0 776.8 1116.6 852.6 857.0 842.8 1996.5 603.6 681.5 756.7 838.3 665.2 981.9 1019.4 407.0 365.8 669.0 376.5 431.6 974.2 610.1 1403.7 1473.7 512.5 396.4 542.2 307.5 441.4 577.6 537.6 288.1 589.9 863.0 620.2 367.7 977.3 281.8 645.6 924.4 710.5 1119.6 826.1 693.6 1324.3 974.6 896.6 755.0 214.2 769.1 849.6 1023.6 955.8 1565.2 487.0 510.5 498.2 574.6 475.9 499.0 509.5 488.1 507.8 504.7 500.7 519.7 412.1 182.7 266.7 0.0 167.8 0.0 0.0 0.0 0.0 0.0 1335.2 1873.6 0.0 0.0 177.0 527.8 0.0 732.4 297.0 0.0 1762.9 470.7 0.0 529.1 446.9 190.2 0.0 0.0 0.0 676.5 777.5 222.2 0.0 454.1 224.5 715.4 0.0 0.0 1076.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.0 0.0 0.0 380.9 0.0 0.0 0.0 0.0 392.7 0.0 0.0 52.8 0.0 0.0 2061.3 215.7 0.0 0.0 0.0 248.9 0.0 0.0 0.0 0.0 507.7 182.6 802.8 0.0 0.0 ATP5MD "bA792D24.4, DAPIT, MGC14697, USMG5" ENSG00000173915 "ATP synthase membrane subunit DAPIT" Q96IX5 10 103389041-103396492 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1340.2;Ductal cells: 705.9;Exocrine glandular cells: 723.1;Pancreatic endocrine cells: 884.5;Proximal tubular cells: 1879.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044798 Supported Mitochondria NA NA 55000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA044798: AB_2679091" "unprognostic (4.41e-2)" "unprognostic (3.08e-2)" "unprognostic (2.59e-1)" "unprognostic (7.93e-2)" "unprognostic (1.65e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (1.57e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (7.46e-2)" "unprognostic (1.03e-2)" 332.3 343.0 502.9 155.1 517.7 193.0 324.6 514.9 721.8 215.1 515.2 484.6 273.5 176.9 410.2 426.1 194.3 140.8 1229.7 526.1 539.0 546.7 587.1 215.3 180.3 501.2 501.9 157.5 321.4 519.2 309.2 157.4 506.1 254.2 449.6 245.3 234.8 236.4 1019.3 204.6 261.7 229.8 511.8 185.4 369.8 142.5 509.3 319.0 191.2 1325.5 251.0 284.7 258.9 518.0 557.8 559.4 528.4 648.2 570.2 696.0 348.3 523.2 612.7 501.0 556.6 925.2 605.3 312.4 288.9 575.3 398.6 559.4 502.2 522.7 697.9 414.7 887.3 331.8 682.1 1057.7 545.7 688.3 491.3 569.2 801.1 456.4 715.7 849.2 661.5 470.0 441.5 517.5 849.4 842.0 552.0 1167.5 397.8 830.1 959.1 355.8 326.0 495.3 1218.4 878.4 203.7 464.8 269.4 419.7 824.9 723.5 373.4 619.9 388.6 255.2 394.2 394.0 692.8 537.2 958.4 543.5 545.2 678.2 200.3 575.3 271.2 395.8 214.7 384.0 248.0 301.6 296.3 259.8 314.1 219.1 251.4 256.7 231.1 230.5 375.3 456.3 307.9 304.4 502.9 517.7 514.9 721.8 526.1 539.0 501.2 501.9 506.1 511.8 509.3 518.0 169.1 211.5 173.2 0.0 40.9 0.0 0.0 0.0 0.0 0.0 323.4 417.6 0.0 0.0 91.0 388.1 0.0 298.0 76.3 0.0 1340.2 705.9 0.0 406.0 245.4 114.5 0.0 0.0 0.0 723.1 439.4 81.8 0.0 424.5 118.6 176.9 0.0 0.0 543.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.4 0.0 0.0 432.6 0.0 0.0 0.0 0.0 884.5 0.0 0.0 0.0 0.0 0.0 1879.7 121.0 0.0 0.0 0.0 127.9 0.0 0.0 0.0 0.0 305.8 69.4 209.9 0.0 0.0 ATP5ME ATP5I ENSG00000169020 "ATP synthase membrane subunit e" P56385 4 672436-674330 "Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2048.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 886.5;Distal tubular cells: 1729.5;Proximal tubular cells: 2485.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035010 Enhanced Supported Mitochondria NA NA 280000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA035010: AB_10669853" "unprognostic (1.42e-1)" "unprognostic (4.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (3.44e-1)" "unprognostic (1.23e-1)" "unprognostic (6.95e-2)" "unprognostic (7.92e-2)" "unprognostic (3.32e-1)" "unprognostic (1.35e-3)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (2.46e-3)" "unprognostic (6.89e-2)" "unprognostic (2.18e-1)" "unprognostic (2.48e-1)" "unprognostic (6.45e-3)" 360.1 412.7 940.1 212.2 960.8 312.4 277.4 981.5 1172.2 263.3 926.5 555.7 460.3 237.4 242.7 511.9 218.8 94.5 1507.7 932.5 968.9 572.0 591.7 235.6 174.6 980.1 955.6 257.5 330.9 774.8 312.8 144.8 972.5 262.0 331.4 336.4 304.8 220.4 2048.3 297.8 436.7 172.8 952.6 281.3 414.9 130.6 960.4 315.7 270.1 1688.5 223.8 293.5 323.8 998.1 542.0 560.8 781.7 599.5 622.4 544.4 390.7 561.8 445.4 407.4 359.4 525.4 548.4 299.0 472.8 612.4 683.8 361.8 668.9 924.1 241.4 249.9 1082.7 854.6 1107.9 1435.2 659.0 1118.6 368.0 721.6 533.5 472.2 491.0 665.5 503.3 608.1 756.0 314.4 464.7 904.5 972.6 1337.3 861.9 1071.7 1438.9 584.4 555.0 620.7 863.9 1053.2 667.7 530.1 401.6 525.0 620.2 502.7 590.4 695.7 580.2 348.0 340.7 308.2 730.9 739.7 1273.2 947.0 528.0 712.7 391.3 1049.3 1044.5 1188.8 742.1 920.0 776.3 1470.4 909.2 839.0 1067.0 1131.6 837.1 811.9 962.2 943.5 822.7 1179.7 1086.3 1456.6 940.1 960.8 981.5 1172.2 932.5 968.9 980.1 955.6 972.5 952.6 960.4 998.1 311.8 153.8 199.7 0.0 88.6 0.0 0.0 0.0 0.0 0.0 461.7 421.8 0.0 0.0 121.9 886.5 0.0 404.9 188.8 0.0 1729.5 467.4 0.0 468.6 315.6 125.1 0.0 0.0 0.0 692.9 335.8 139.4 0.0 484.2 122.4 311.8 0.0 0.0 676.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 201.6 0.0 0.0 278.1 0.0 0.0 0.0 0.0 509.6 0.0 0.0 50.1 0.0 0.0 2485.3 183.6 0.0 0.0 0.0 156.7 0.0 0.0 0.0 0.0 274.9 97.8 146.6 0.0 0.0 ATP5MF "ATP5J2, ATP5JL" ENSG00000241468 "ATP synthase membrane subunit f" P56134 7 99448475-99466186 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 777.4;Distal tubular cells: 1430.2;Exocrine glandular cells: 578.8;Extravillous trophoblasts: 636.3;Hofbauer cells: 787.4;Pancreatic endocrine cells: 589.5;Proximal tubular cells: 1616.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067267, HPA070412" Approved Supported "Nuclear membrane,Mitochondria" NA NA 60000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Nuclear membrane" "HPA067267: AB_2685815, HPA070412: AB_2686266" "unprognostic (2.43e-2)" "unprognostic (1.42e-1)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (4.55e-3)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (6.19e-2)" "unprognostic (2.31e-3)" "unprognostic (2.58e-1)" "unprognostic (3.65e-2)" "unprognostic (6.88e-3)" "unprognostic (9.24e-2)" "unprognostic (4.90e-2)" "unprognostic (2.52e-1)" "unprognostic (5.78e-2)" 328.8 423.5 636.9 268.7 655.2 404.4 310.8 658.3 868.4 247.8 671.0 470.9 442.7 188.3 299.1 526.6 191.7 143.8 1184.8 658.1 663.7 559.3 561.2 241.8 293.1 657.5 648.0 179.1 271.6 509.6 332.1 235.7 647.0 315.5 367.9 320.7 317.8 205.9 1337.1 287.0 384.6 192.0 637.6 281.8 354.7 310.5 652.7 439.3 241.4 1439.0 301.2 303.1 303.5 641.3 1251.5 1130.6 905.3 1400.5 752.1 739.2 561.1 799.3 705.9 947.2 994.6 1226.2 1091.7 1161.7 822.7 548.5 1513.9 735.7 1064.0 981.3 1021.4 831.0 1333.6 800.1 1584.6 1555.4 530.7 1324.4 824.4 835.6 944.9 766.6 858.9 760.5 919.8 1009.4 1681.6 1213.0 1057.4 3128.1 1984.5 2396.1 1228.2 2594.9 1410.9 874.9 741.6 1985.9 1936.7 1376.1 845.3 925.9 1073.7 2519.4 773.1 1365.1 644.9 1687.5 703.0 706.0 1142.1 1197.3 1181.5 685.7 1795.6 2432.4 829.7 1325.8 1131.8 1020.3 904.1 1069.1 440.2 912.7 425.6 597.7 508.3 494.8 1122.9 512.2 445.1 468.3 428.0 555.2 731.2 890.5 754.9 1505.3 636.9 655.2 658.3 868.4 658.1 663.7 657.5 648.0 647.0 637.6 652.7 641.3 147.7 22.4 44.9 0.0 57.9 0.0 0.0 0.0 0.0 0.0 252.4 289.6 0.0 0.0 36.5 386.2 0.0 777.4 125.6 0.0 1430.2 460.9 0.0 302.6 225.3 82.0 0.0 0.0 0.0 578.8 636.3 110.5 0.0 278.3 64.3 188.1 0.0 0.0 787.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 190.2 0.0 0.0 339.1 0.0 0.0 0.0 0.0 589.5 0.0 0.0 18.6 0.0 0.0 1616.3 51.0 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 436.3 64.0 206.4 0.0 0.0 ATP5MG "ATP5JG, ATP5L" ENSG00000167283 "ATP synthase membrane subunit g" O75964 11 118401606-118431496 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1407.2;Distal tubular cells: 2907.4;Hofbauer cells: 1367.3;Proximal tubular cells: 2520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044629 Approved Supported Mitochondria NA NA 44000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA044629: AB_2679028" "unprognostic (1.70e-1)" "unprognostic (2.40e-2)" "unprognostic (2.21e-1)" "unprognostic (5.45e-2)" "unprognostic (1.61e-1)" "unprognostic (3.27e-2)" "unprognostic (3.90e-2)" "unprognostic (8.19e-2)" "unprognostic (5.13e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (7.41e-2)" "prognostic favorable (4.09e-5)" "unprognostic (6.26e-2)" "unprognostic (2.56e-1)" "unprognostic (1.50e-2)" "unprognostic (3.05e-2)" 119.8 137.2 154.2 103.3 158.5 165.6 132.5 158.5 184.3 81.1 168.3 153.6 146.4 79.3 143.3 116.9 96.5 68.1 329.8 157.2 160.8 205.1 154.5 77.9 150.0 155.5 153.1 112.0 110.9 140.7 49.5 83.7 154.0 83.5 164.3 100.8 133.9 92.2 340.7 55.3 118.2 95.2 153.6 86.0 112.3 46.9 155.5 204.1 87.5 373.6 183.1 105.3 41.5 154.7 163.1 87.9 209.3 183.1 167.6 198.0 200.1 149.0 175.9 138.4 146.6 259.9 259.9 314.3 352.7 167.5 206.2 190.4 204.4 214.8 155.3 247.6 138.0 472.8 112.5 197.4 175.3 279.3 210.2 207.1 203.4 169.0 162.9 164.1 189.8 216.6 227.4 253.1 199.5 305.8 365.2 497.3 130.1 427.9 224.0 247.0 174.9 422.9 371.1 260.3 184.3 161.9 232.3 361.1 161.9 221.6 303.0 307.7 172.8 123.0 144.7 109.2 190.9 112.8 184.8 402.1 93.8 353.0 154.7 325.4 437.2 299.0 241.8 360.8 339.7 462.7 398.8 321.5 481.2 378.5 472.9 379.7 214.8 357.2 333.3 534.3 464.5 1112.1 154.2 158.5 158.5 184.3 157.2 160.8 155.5 153.1 154.0 153.6 155.5 154.7 324.3 362.2 364.1 0.0 211.2 0.0 0.0 0.0 0.0 0.0 893.9 1061.2 0.0 0.0 166.5 610.6 0.0 1407.2 378.3 0.0 2907.4 748.6 0.0 449.8 327.9 188.9 0.0 0.0 0.0 986.0 935.6 204.7 0.0 404.6 258.6 368.2 0.0 0.0 1367.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 427.7 0.0 0.0 678.1 0.0 0.0 0.0 0.0 922.2 0.0 0.0 94.9 0.0 0.0 2520.3 188.0 0.0 0.0 0.0 217.5 0.0 0.0 0.0 0.0 1001.4 224.2 370.0 0.0 0.0 ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 135.8;tongue: 131.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 346.5;Distal tubular cells: 461.8;Extravillous trophoblasts: 405.2;Hofbauer cells: 373.0;Proximal tubular cells: 434.6;Syncytiotrophoblasts: 347.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046067, HPA057347" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046067: AB_10960850, HPA057347: AB_2683416" "unprognostic (4.18e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-3)" "unprognostic (1.73e-2)" "unprognostic (3.56e-2)" "unprognostic (8.18e-2)" "unprognostic (8.52e-3)" "unprognostic (8.82e-2)" "unprognostic (3.67e-2)" "unprognostic (7.18e-3)" "unprognostic (3.29e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.26e-9)" "prognostic favorable (8.07e-4)" "unprognostic (1.60e-1)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" 19.3 15.7 10.3 11.5 12.5 15.3 18.8 14.5 27.4 17.4 3.9 51.6 28.8 16.6 16.0 26.8 23.9 16.3 109.0 12.1 10.2 40.3 40.2 13.7 24.0 13.4 12.0 19.2 18.5 33.8 7.1 21.6 14.9 22.3 33.6 28.5 29.8 18.7 135.8 15.7 19.0 17.9 9.6 15.2 22.6 15.5 12.8 15.7 31.1 131.0 22.4 21.9 7.4 14.1 55.6 17.6 44.1 36.9 35.6 34.2 34.1 57.0 68.9 67.3 54.7 31.8 29.1 84.9 52.3 45.5 14.3 56.1 69.4 79.5 65.1 61.9 33.2 76.1 21.3 21.5 26.0 98.3 70.8 30.3 40.9 69.3 66.9 17.7 60.0 11.9 78.7 33.6 46.3 35.4 153.3 30.0 34.9 19.2 90.5 41.2 143.6 34.0 54.7 26.0 37.2 13.4 49.4 72.7 55.6 12.6 54.8 46.0 50.6 32.0 49.1 59.4 61.2 41.8 44.5 172.1 70.8 77.6 60.8 3.5 15.4 7.1 14.8 10.0 12.2 12.9 15.1 13.3 16.1 15.2 16.9 10.4 4.8 9.8 9.0 9.2 15.1 44.2 10.3 12.5 14.5 27.4 12.1 10.2 13.4 12.0 14.9 9.6 12.8 14.1 73.2 67.3 83.8 0.0 31.5 0.0 0.0 0.0 0.0 0.0 112.9 155.3 0.0 0.0 57.6 125.0 0.0 346.5 56.4 0.0 461.8 237.3 0.0 132.5 111.0 58.8 0.0 0.0 0.0 196.7 405.2 57.0 0.0 125.4 89.6 82.1 0.0 0.0 373.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.8 0.0 0.0 98.8 0.0 0.0 0.0 0.0 162.6 0.0 0.0 9.8 0.0 0.0 434.6 74.3 0.0 0.0 0.0 58.0 0.0 0.0 0.0 0.0 347.7 41.8 208.0 0.0 0.0 ATP5PD "ATP5H, ATP5JD, ATPQ" ENSG00000167863 "ATP synthase peripheral stalk subunit d" O75947 17 75038863-75046985 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1142.6;Hofbauer cells: 465.0;Proximal tubular cells: 1059.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042777, HPA048459" Enhanced Supported Mitochondria NA NA 60000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042777: AB_2678160, HPA048459: AB_2680402" "unprognostic (1.37e-1)" "unprognostic (4.41e-2)" "unprognostic (1.70e-3)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "unprognostic (4.81e-2)" "unprognostic (7.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (2.72e-1)" "unprognostic (8.72e-2)" "unprognostic (2.56e-2)" "unprognostic (1.42e-1)" "unprognostic (3.26e-1)" "unprognostic (1.73e-1)" "unprognostic (4.29e-2)" 253.8 271.0 253.5 156.0 260.5 187.2 228.8 270.5 385.7 190.7 282.9 337.1 295.1 170.7 279.9 355.9 173.5 140.1 985.5 261.9 271.1 465.2 454.2 174.0 166.0 264.8 256.9 147.5 222.2 427.1 203.9 174.1 260.8 177.9 323.6 256.0 240.8 200.5 1102.8 264.7 257.4 211.3 260.2 155.0 307.4 93.8 262.3 175.2 263.7 1025.5 221.2 230.3 221.5 261.7 522.8 445.4 335.6 439.8 532.6 647.4 449.1 437.2 571.3 478.5 452.2 351.8 397.1 349.8 282.5 550.2 450.2 462.2 409.0 571.6 637.5 171.6 346.0 359.1 340.2 703.1 524.2 463.5 225.8 555.3 444.8 390.7 552.7 380.9 646.8 268.5 380.1 462.6 595.1 503.3 461.8 515.6 257.1 1185.3 626.9 322.3 970.4 652.3 1007.3 499.7 335.8 368.5 515.5 811.0 730.7 496.9 805.1 463.2 337.4 591.1 413.2 520.0 520.4 369.0 315.5 360.8 530.2 455.4 390.3 410.8 440.7 481.0 274.8 540.9 320.8 364.5 467.5 341.7 509.7 292.8 416.1 388.9 253.0 301.6 458.0 453.6 492.8 495.9 253.5 260.5 270.5 385.7 261.9 271.1 264.8 256.9 260.8 260.2 262.3 261.7 173.8 173.1 156.4 0.0 35.0 0.0 0.0 0.0 0.0 0.0 159.6 234.2 0.0 0.0 102.8 259.3 0.0 384.3 74.0 0.0 1142.6 313.6 0.0 188.2 153.6 70.4 0.0 0.0 0.0 379.5 328.4 82.7 0.0 207.6 88.3 84.6 0.0 0.0 465.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.1 0.0 0.0 208.8 0.0 0.0 0.0 0.0 284.3 0.0 0.0 13.8 0.0 0.0 1059.2 101.3 0.0 0.0 0.0 88.3 0.0 0.0 0.0 0.0 336.3 54.4 155.9 0.0 0.0 ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 263.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 284.7;Distal tubular cells: 172.1;Early spermatids: 261.4;Late spermatids: 373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028382: AB_2672574, HPA044950: AB_2679151" "unprognostic (1.34e-1)" "unprognostic (2.97e-3)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (5.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "prognostic favorable (5.33e-7)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" 66.0 89.9 87.5 23.3 94.4 27.4 30.2 97.1 115.2 30.0 102.8 44.9 35.3 22.5 29.4 30.1 27.3 25.8 221.0 82.9 107.7 97.1 95.3 21.9 27.9 85.8 85.6 28.8 41.2 121.5 43.8 32.3 85.3 32.2 48.1 63.9 48.4 29.0 221.0 20.1 35.2 32.3 80.7 21.6 42.1 41.5 90.6 37.8 37.1 263.4 28.5 26.4 20.2 82.2 57.8 46.1 61.1 54.8 65.1 52.3 51.0 42.2 52.6 62.0 49.7 37.2 24.5 34.1 55.2 53.6 54.9 43.6 97.3 54.7 83.1 75.0 76.7 60.2 54.5 65.0 52.4 60.2 3.4 51.4 64.3 66.5 57.7 49.2 39.3 62.8 28.2 65.4 48.0 52.3 89.3 33.3 96.3 49.8 68.8 38.1 16.5 74.3 71.4 45.2 71.8 53.8 71.4 74.9 114.6 70.0 69.3 83.8 34.4 21.1 52.1 43.1 58.5 80.6 78.9 23.2 34.7 23.0 40.6 0.0 1.6 4.1 2.1 2.8 2.7 1.8 2.2 2.5 1.6 1.2 3.1 1.4 1.3 5.6 1.2 1.2 4.5 1.2 87.5 94.4 97.1 115.2 82.9 107.7 85.8 85.6 85.3 80.7 90.6 82.2 12.6 3.2 18.6 31.0 22.3 9.4 21.2 9.7 27.3 34.0 27.8 19.4 284.7 31.5 13.1 31.3 27.1 64.0 14.5 26.7 172.1 22.1 261.4 15.6 15.4 13.2 19.2 31.3 37.1 20.1 30.0 28.5 29.0 15.9 15.9 40.6 10.4 39.8 39.2 47.1 48.5 38.1 16.2 21.6 12.9 373.7 19.0 16.1 24.9 15.9 14.6 39.2 15.5 28.1 33.7 11.3 18.0 26.7 36.3 15.2 30.2 119.1 10.2 29.2 26.3 25.1 28.9 45.2 40.4 34.3 13.5 46.9 19.2 55.1 42.2 21.9 ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 104.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023329, HPA059422" Supported Enhanced Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA023329: AB_1845209, HPA059422: AB_2684011" "unprognostic (3.16e-2)" "unprognostic (1.98e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.95e-4)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (2.70e-3)" "unprognostic (1.67e-2)" "prognostic favorable (6.00e-5)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (5.15e-1)" "unprognostic (2.62e-2)" 8.6 18.5 7.4 8.6 7.6 15.9 8.7 8.3 11.1 8.4 8.3 11.1 8.7 6.8 8.7 14.4 8.1 4.9 23.9 7.5 9.1 16.1 19.7 7.8 10.5 7.9 8.1 7.3 9.8 26.3 9.3 7.7 8.4 9.1 10.4 6.4 10.7 6.6 24.7 14.6 10.2 8.4 7.8 10.4 12.0 10.9 7.8 10.8 10.6 27.8 14.5 9.1 9.5 8.4 13.0 24.1 15.4 14.7 15.1 16.2 15.6 11.2 16.4 23.7 20.1 31.8 19.3 26.0 24.6 19.5 13.1 19.9 14.8 24.1 20.7 20.9 11.7 5.8 14.8 18.6 25.5 8.2 17.3 19.5 16.8 21.4 11.9 16.7 27.4 21.3 9.3 8.9 13.1 26.8 19.4 12.8 10.4 48.3 13.3 19.8 27.1 29.9 19.0 11.4 9.9 13.5 14.9 7.6 14.0 104.2 24.4 16.2 11.6 6.0 12.4 22.2 10.9 6.2 8.4 9.6 10.7 11.9 31.4 7.8 41.5 14.7 9.3 28.6 10.4 27.9 6.9 8.9 49.2 19.7 10.7 8.0 3.0 8.9 22.3 41.6 12.9 20.7 7.4 7.6 8.3 11.1 7.5 9.1 7.9 8.1 8.4 7.8 7.8 8.4 8.8 6.4 7.8 9.4 20.3 15.3 12.0 23.7 9.6 10.5 13.9 10.8 28.2 20.0 14.4 12.9 33.3 32.5 20.7 10.9 66.5 19.3 52.9 10.5 6.0 10.0 14.5 13.7 13.7 12.3 30.9 9.1 8.2 8.5 13.3 25.7 9.3 20.8 45.5 10.1 14.1 18.2 16.2 22.3 22.5 42.6 6.5 18.2 17.8 7.5 28.1 13.8 13.4 9.0 9.6 16.0 24.4 6.8 18.6 13.8 25.8 58.8 17.2 17.7 0.0 8.4 10.4 28.2 20.9 17.6 18.9 28.7 9.0 15.9 20.5 12.3 AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361918 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 191.7;Inhibitory neurons: 137.0;Oligodendrocytes: 137.5;Proximal tubular cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" 17.2 41.9 11.8 6.3 12.3 4.8 15.9 16.0 15.3 13.6 17.9 17.2 23.8 10.2 14.2 8.6 12.4 10.7 38.9 12.1 14.3 62.9 26.4 10.3 7.6 14.8 13.6 13.4 25.5 45.4 10.4 16.1 15.2 28.2 17.2 21.4 26.1 14.8 24.2 8.7 20.1 8.6 12.2 8.0 22.7 5.5 14.1 9.0 21.0 29.2 7.7 9.1 9.8 15.0 9.1 8.7 12.0 6.2 14.5 15.5 18.5 8.0 10.0 6.1 7.0 5.0 11.4 10.6 8.1 8.5 18.2 13.0 18.1 10.1 8.7 82.6 15.4 7.3 9.7 29.6 11.1 10.6 7.3 13.1 12.5 4.9 16.8 14.3 7.6 10.7 10.3 15.5 7.2 8.8 14.6 23.8 15.0 22.2 12.5 8.5 9.6 18.6 26.6 4.8 12.2 8.8 11.9 28.3 15.6 27.1 5.2 6.9 7.8 6.1 7.6 9.0 7.8 17.7 16.1 3.6 9.6 8.5 4.2 17.9 5.2 18.2 7.2 3.6 8.1 8.4 7.8 10.4 4.6 11.8 9.6 9.1 7.4 10.8 2.5 6.3 10.8 6.5 11.8 12.3 16.0 15.3 12.1 14.3 14.8 13.6 15.2 12.2 14.1 15.0 9.6 0.0 7.7 75.1 11.2 5.2 24.5 27.7 12.5 18.7 15.8 13.5 37.2 27.1 19.1 27.6 25.0 44.6 11.5 27.0 191.7 29.6 3.1 11.5 11.1 11.1 22.9 28.8 101.2 16.1 28.9 14.2 19.4 16.0 1.3 14.5 11.0 18.3 13.4 13.5 137.0 17.3 38.7 8.9 4.7 1.1 14.3 8.9 12.4 67.5 29.1 9.5 18.6 100.5 137.5 12.5 23.5 11.3 18.4 36.8 59.4 120.0 15.8 34.4 13.1 11.9 11.5 8.7 10.5 16.1 4.1 36.4 12.9 11.6 25.0 24.2 AURKAIP1 "AIP, AKIP, FLJ20608" ENSG00000175756 "Aurora kinase A interacting protein 1" Q9NWT8 1 1373730-1375495 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1314.3;Late spermatids: 3668.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031821 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA031821: AB_10601458" "unprognostic (9.54e-2)" "unprognostic (1.86e-2)" "unprognostic (2.77e-1)" "unprognostic (4.77e-2)" "unprognostic (2.68e-1)" "unprognostic (2.98e-2)" "unprognostic (3.31e-1)" "unprognostic (9.52e-2)" "unprognostic (2.76e-1)" "unprognostic (9.91e-2)" "unprognostic (3.39e-2)" "unprognostic (3.34e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.18e-2)" "unprognostic (1.84e-1)" 98.0 129.1 116.2 43.4 117.6 51.5 90.0 125.2 142.4 64.9 130.2 110.5 71.7 70.0 23.5 118.0 64.1 26.1 260.8 113.4 116.3 151.8 215.8 67.2 41.4 125.6 116.8 58.2 120.1 73.4 92.3 35.8 116.1 85.9 27.5 23.6 88.2 38.7 281.3 91.0 85.6 22.4 116.9 85.8 121.4 300.6 128.4 37.9 83.1 171.3 27.2 87.2 72.9 118.4 197.8 116.9 62.9 113.6 54.6 68.2 115.7 116.8 76.8 180.7 127.6 206.3 177.5 103.2 169.3 79.6 90.7 142.4 86.5 154.6 51.9 124.7 245.8 83.6 156.1 194.0 106.7 109.0 109.0 90.4 68.6 127.1 51.3 52.8 99.2 96.3 167.2 138.5 106.6 150.3 134.7 386.9 119.1 123.2 329.1 154.8 77.5 222.7 145.9 51.6 200.7 150.6 83.7 288.4 295.1 38.1 125.0 250.7 75.5 111.3 144.4 134.1 175.7 179.1 177.0 223.4 155.3 159.2 77.1 279.1 231.8 266.6 171.6 200.3 162.7 190.6 178.4 181.7 207.4 202.7 166.6 161.1 291.7 142.4 177.7 294.0 230.1 225.6 116.2 117.6 125.2 142.4 113.4 116.3 125.6 116.8 116.1 116.9 128.4 118.4 118.9 48.1 73.5 18.9 137.4 162.3 166.4 271.4 87.0 109.8 228.1 240.2 231.3 180.1 149.6 165.5 64.6 384.1 134.7 642.0 677.0 310.2 1314.3 145.6 119.3 127.6 203.9 125.2 11.2 418.4 458.6 121.0 178.4 141.8 87.5 144.6 121.1 390.5 294.6 104.3 12.8 415.1 238.0 154.8 175.5 3668.5 136.1 149.7 217.1 5.6 208.1 299.8 166.9 13.0 17.9 425.2 484.3 118.5 240.5 272.5 607.4 780.2 142.2 124.5 157.8 104.4 152.4 572.4 149.2 190.4 197.6 438.1 116.3 181.0 414.3 270.1 B3GALT2 beta3Gal-T2 ENSG00000162630 "Beta-1,3-galactosyltransferase 2" O43825 1 193178730-193186613 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.2;gallbladder: 15.0;heart muscle: 21.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 46.6;Cardiomyocytes: 34.4;Excitatory neurons: 27.6;Inhibitory neurons: 28.3;Leydig cells: 31.7;Peritubular cells: 21.1" "Cancer enhanced" "Detected in some" "glioma: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "MAIT T-cell: 8.4" "Lineage enriched" "Detected in single" 53 "T-cells: 8.4" "Group enriched" "Detected in some" 4 "AF22: 18.3;ASC TERT1: 8.1;LHCN-M2: 12.6;WM-115: 21.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078659 Approved "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA078659: AB_2686887" "unprognostic (1.83e-2)" "unprognostic (3.81e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (1.58e-3)" "unprognostic (2.34e-3)" "unprognostic (2.43e-3)" "unprognostic (1.63e-1)" "unprognostic (2.44e-1)" "unprognostic (6.14e-4)" "unprognostic (4.41e-2)" "unprognostic (8.10e-3)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-3)" 0.3 1.2 13.4 0.7 15.3 0.2 0.3 4.9 17.1 0.2 2.3 1.0 0.9 0.1 1.0 0.6 0.2 15.0 21.0 17.2 7.1 0.9 0.2 1.8 0.2 5.8 7.4 10.4 0.2 0.0 0.5 0.3 5.8 4.7 1.2 6.6 0.1 5.1 0.1 0.2 3.0 0.1 7.0 0.8 1.3 0.7 8.5 0.0 1.0 0.3 0.9 1.4 0.3 15.9 0.0 0.0 18.3 0.0 0.5 8.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.6 1.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.2 0.0 8.4 0.0 1.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.2 13.4 15.3 4.9 17.1 17.2 7.1 5.8 7.4 5.8 7.0 8.5 15.9 0.6 0.0 0.5 1.6 0.9 0.3 0.1 0.0 0.6 46.6 0.0 0.1 34.4 11.5 0.0 1.8 4.2 0.0 0.2 0.1 0.0 0.1 0.0 0.3 1.3 1.1 3.0 0.8 27.6 0.0 0.0 2.0 0.0 0.9 2.5 0.4 0.7 0.1 0.3 8.4 28.3 0.7 0.0 0.6 0.3 0.7 31.7 0.7 0.0 4.7 0.0 2.4 0.0 12.1 9.3 0.5 0.1 21.1 0.4 0.1 3.4 0.1 2.2 6.2 0.0 0.3 1.2 0.0 0.0 0.3 0.3 0.0 4.9 0.3 0.5 0.0 B4GAT1 "B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT" ENSG00000174684 "Beta-1,4-glucuronyltransferase 1" O43505 11 66345374-66347629 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.3;Horizontal cells: 158.2;Muller glia cells: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015484 Uncertain "Intracellular and membrane" NA NA 57000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA015484: AB_1845235" "unprognostic (1.80e-1)" "unprognostic (7.20e-2)" "unprognostic (1.70e-1)" "unprognostic (3.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.45e-1)" "unprognostic (9.23e-2)" "unprognostic (1.59e-1)" "unprognostic (2.65e-2)" "unprognostic (3.43e-3)" "prognostic favorable (3.55e-5)" "unprognostic (2.20e-1)" "unprognostic (3.50e-1)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.76e-3)" 16.6 41.4 120.6 6.1 124.9 1.3 16.0 71.0 125.2 23.1 68.7 30.1 16.2 28.5 15.2 8.3 23.4 9.9 44.6 115.3 220.2 25.3 18.8 17.3 6.7 85.9 97.3 34.3 25.5 22.6 62.3 22.5 101.0 17.3 7.7 46.0 15.8 22.4 27.7 12.1 14.6 14.0 91.9 10.2 25.8 8.2 150.4 6.5 21.0 19.2 4.3 20.2 16.3 83.9 10.8 26.7 29.7 36.5 32.6 29.3 39.4 18.4 42.5 28.1 22.9 20.1 14.9 8.9 76.1 16.9 24.1 16.8 32.0 20.6 13.5 17.6 58.2 1.3 20.4 77.6 19.3 7.0 2.7 28.6 15.6 17.5 7.4 92.8 33.5 14.8 8.6 13.7 13.6 18.1 16.7 19.1 20.2 10.6 28.0 24.0 23.2 15.9 29.6 2.7 17.8 33.7 15.8 10.4 74.8 18.4 42.6 6.8 19.7 21.8 15.9 28.0 9.6 26.1 19.2 5.3 36.8 5.8 26.0 0.0 1.2 0.0 7.1 0.4 9.9 5.7 7.8 7.6 3.0 3.2 9.0 8.3 0.4 4.6 0.3 7.4 5.7 4.4 120.6 124.9 71.0 125.2 115.3 220.2 85.9 97.3 101.0 91.9 150.4 83.9 13.5 22.4 10.8 25.8 2.9 0.0 1.6 0.0 14.2 72.3 6.2 12.7 45.9 25.8 1.8 20.2 58.4 57.8 8.6 8.0 5.9 7.4 0.5 3.9 9.7 17.1 4.9 0.8 22.1 6.0 22.6 23.4 6.6 2.6 1.3 22.5 30.4 24.4 12.7 158.2 35.0 8.0 0.0 2.4 0.0 2.4 32.6 2.6 0.0 10.3 1.3 70.1 2.1 22.6 14.2 4.3 4.9 40.6 6.1 2.0 13.3 17.5 2.9 47.4 26.3 21.2 11.8 1.4 2.8 5.8 0.0 18.1 2.6 28.0 7.2 0.3 BCAT2 "BCAM, BCT2" ENSG00000105552 "Branched chain amino acid transaminase 2" O15382 19 48795062-48811029 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 254.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054091 Enhanced Approved Nucleoplasm,Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" "HPA054091: AB_2682374" "unprognostic (2.58e-2)" "unprognostic (1.23e-2)" "unprognostic (2.16e-1)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.97e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (2.98e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.68e-5)" "unprognostic (1.87e-3)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (7.50e-3)" 27.2 85.4 27.5 11.4 27.8 6.1 25.2 34.6 34.5 29.7 72.3 38.8 14.8 27.0 5.3 33.7 30.2 10.7 63.4 29.0 26.5 40.5 22.1 30.4 14.0 28.2 29.7 53.3 76.7 20.1 30.7 12.4 27.8 38.4 17.4 5.6 29.1 17.0 58.7 28.0 23.7 13.5 26.1 19.7 66.4 20.2 30.8 12.0 28.9 29.4 16.5 56.6 29.0 29.2 62.9 73.3 19.3 40.6 78.1 26.3 34.2 27.3 13.8 32.7 31.7 74.5 37.4 73.3 30.2 24.3 10.1 28.8 29.8 47.4 16.5 46.0 76.0 27.0 32.7 5.0 75.3 36.9 24.2 38.5 29.8 24.2 35.0 31.8 45.5 55.3 34.9 43.8 12.2 74.8 50.4 38.9 16.9 98.5 35.7 75.2 33.1 80.8 30.8 254.3 102.6 29.4 41.0 66.7 20.7 13.3 42.3 17.9 25.9 31.5 30.3 37.6 34.3 40.8 58.4 35.8 17.2 56.7 21.0 0.0 14.4 3.0 14.3 16.1 20.1 23.5 17.5 18.8 25.6 20.3 15.7 14.1 0.6 14.8 6.2 28.9 24.9 12.3 27.5 27.8 34.6 34.5 29.0 26.5 28.2 29.7 27.8 26.1 30.8 29.2 13.1 28.9 44.8 59.7 14.1 6.0 28.3 32.3 14.2 10.4 23.5 17.9 25.5 31.5 20.6 12.9 20.9 67.6 11.0 28.8 72.4 38.6 8.0 16.2 22.4 13.5 19.9 6.3 11.2 21.3 25.2 15.3 32.6 23.8 23.5 18.3 12.8 11.2 26.2 1.7 10.6 30.4 38.7 7.9 10.5 10.2 17.4 7.5 24.9 8.4 21.6 7.3 7.2 9.0 11.2 15.8 17.7 30.1 15.1 16.1 13.9 39.4 13.2 13.4 19.7 9.9 17.3 8.0 19.5 32.6 7.1 45.8 9.5 21.9 33.9 47.7 BCKDHA "MSU, OVD1A" ENSG00000248098 "Branched chain keto acid dehydrogenase E1 subunit alpha" P12694 19 41397808-41425002 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.2;Gastric mucus-secreting cells: 23.4;Plasma cells: 25.0;Squamous epithelial cells: 27.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036640 Supported NA NA 7700 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "HPA036640: AB_10671964" "unprognostic (4.50e-2)" "unprognostic (6.85e-2)" "unprognostic (1.14e-1)" "unprognostic (8.58e-3)" "unprognostic (1.26e-2)" "prognostic favorable (9.37e-4)" "unprognostic (2.41e-2)" "unprognostic (8.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.53e-1)" "prognostic favorable (5.33e-10)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.27e-5)" "unprognostic (9.66e-2)" 33.8 78.4 32.0 19.3 35.5 32.4 25.2 37.0 39.3 24.6 37.0 20.9 19.9 17.9 14.1 65.1 28.8 15.4 90.4 32.5 35.1 44.3 110.0 22.4 24.5 34.4 33.8 25.4 46.1 56.3 24.0 19.0 36.2 23.8 15.0 21.7 40.9 23.1 110.0 31.8 18.7 12.7 33.9 24.4 52.5 27.1 35.7 27.0 41.7 122.0 21.2 21.7 31.9 40.0 42.7 75.1 14.2 44.1 22.2 12.8 17.1 11.9 25.3 24.4 29.9 18.2 36.0 34.6 23.7 15.1 11.0 17.1 15.0 25.9 12.1 36.0 41.0 27.1 35.2 21.3 51.5 25.5 17.7 27.6 37.6 16.9 38.2 36.0 45.0 50.9 25.9 68.9 17.6 41.5 28.0 20.0 12.8 61.1 21.1 27.1 22.8 89.6 29.8 19.8 32.5 38.6 39.6 84.7 34.1 12.1 45.4 81.0 29.3 22.2 23.0 12.0 22.0 131.9 55.1 34.1 81.8 56.6 24.6 61.4 149.4 59.7 49.5 123.9 56.7 46.0 47.0 49.1 154.6 49.5 43.2 44.9 46.4 82.4 95.5 62.6 63.9 125.6 32.0 35.5 37.0 39.3 32.5 35.1 34.4 33.8 36.2 33.9 35.7 40.0 0.6 0.0 13.1 4.9 10.0 0.3 0.1 2.6 26.2 0.2 1.5 0.4 0.1 1.5 5.3 5.5 0.0 1.9 0.9 3.8 3.9 14.7 0.7 0.5 0.6 2.4 6.1 15.5 5.8 11.8 1.7 3.7 23.4 0.7 5.1 0.4 2.5 2.4 2.7 0.0 6.2 7.6 8.2 2.2 0.8 0.9 0.6 6.6 3.6 3.7 12.4 0.4 5.2 4.0 5.7 8.4 3.8 0.4 25.0 0.2 6.7 2.3 1.2 1.2 0.0 0.2 3.6 1.8 0.9 27.2 0.9 2.1 6.3 0.3 7.3 0.1 BCKDK ENSG00000103507 "Branched chain keto acid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 95.9;granulocytes: 89.7;monocytes: 115.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA017995: AB_1845309, HPA056067: AB_2683024" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 32.3 56.4 18.4 19.2 18.6 14.5 29.0 17.4 23.8 25.1 18.0 31.4 16.0 27.7 16.7 29.4 24.8 17.9 78.6 18.8 17.8 43.8 76.4 21.7 15.6 20.6 20.7 27.5 70.5 22.9 16.4 15.3 19.3 29.3 12.5 6.3 47.0 21.8 81.3 45.4 24.1 19.5 17.1 30.2 42.0 17.4 18.5 9.8 22.4 69.7 13.6 30.2 24.6 17.5 47.5 49.1 27.1 41.8 32.8 32.5 31.1 40.4 46.3 57.3 55.9 32.1 29.1 41.5 58.9 47.5 28.0 31.4 19.3 65.6 36.5 34.4 60.1 45.2 32.6 59.5 57.5 23.5 41.9 48.3 26.2 49.2 40.6 52.6 62.4 31.1 23.4 39.4 87.7 75.8 22.9 32.4 23.0 20.5 39.1 45.8 39.6 78.8 44.3 30.1 42.1 38.7 31.3 72.4 24.6 22.9 44.5 24.6 41.1 44.2 26.1 45.8 32.2 44.5 15.7 15.1 50.3 33.7 42.6 58.1 115.0 85.2 17.7 97.6 17.2 22.8 16.5 13.9 95.9 19.0 13.6 16.1 89.7 22.8 71.2 19.3 24.5 53.1 18.4 18.6 17.4 23.8 18.8 17.8 20.6 20.7 19.3 17.1 18.5 17.5 27.2 19.2 18.1 5.9 20.0 18.5 24.6 61.0 22.2 11.6 30.9 27.6 39.1 25.8 28.5 20.2 0.0 55.4 9.0 31.5 80.3 68.6 2.5 14.6 24.3 29.2 19.9 16.4 5.1 78.0 71.1 24.9 25.5 20.0 33.0 35.4 25.4 43.8 93.0 11.8 4.4 22.3 42.7 44.5 50.3 7.8 20.8 53.1 12.4 1.9 79.3 22.6 9.2 4.5 4.5 54.8 48.4 25.6 51.7 30.9 66.9 95.2 19.6 9.8 46.0 18.4 33.2 25.8 14.1 25.7 27.4 69.4 12.1 45.5 26.0 27.0 BCL11A "BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856" ENSG00000119866 "BAF chromatin remodeling complex subunit BCL11A" Q9H165 2 60450520-60554467 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.8;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "B-cells: 149.0;Basal squamous epithelial cells: 118.4;dendritic cells: 140.3;Excitatory neurons: 180.8;Inhibitory neurons: 153.2;Squamous epithelial cells: 120.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 312.7;naive B-cell: 415.7;plasmacytoid DC: 899.0" "Group enriched" "Detected in all" 15 "B-cells: 415.7;dendritic cells: 899.0" "Cell line enhanced" "Detected in many" "Daudi: 51.1;MOLT-4: 49.0;REH: 48.3;U-698: 106.7;U-937: 34.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 52.5;cerebral cortex: 82.3;hippocampal formation: 69.2;olfactory bulb: 66.7" "CAB014891, HPA029003, HPA075941" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "CAB014891: , HPA029003: AB_2672863, HPA075941: " "unprognostic (4.10e-3)" "unprognostic (6.72e-2)" "unprognostic (4.50e-2)" "unprognostic (9.41e-3)" "unprognostic (2.37e-1)" "unprognostic (4.47e-3)" "unprognostic (2.53e-2)" "unprognostic (1.68e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (4.27e-4)" "unprognostic (1.23e-2)" "unprognostic (2.35e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-1)" "unprognostic (4.40e-2)" "unprognostic (2.99e-2)" 0.7 2.1 31.4 11.3 34.7 25.3 7.1 10.5 47.8 5.2 9.7 18.4 9.7 2.1 1.4 18.4 5.7 2.5 8.0 38.7 15.5 1.0 0.5 2.1 29.2 31.6 15.3 0.6 10.8 1.7 3.0 0.9 31.0 7.8 6.1 1.7 13.8 1.9 1.7 33.2 13.9 3.4 15.9 19.6 4.8 2.0 15.9 33.9 2.3 0.2 40.9 3.3 11.5 38.7 0.6 0.0 4.2 0.1 0.8 0.8 0.3 1.5 0.0 0.1 0.0 0.0 0.2 51.1 0.2 0.2 0.0 10.5 15.4 7.4 0.2 0.9 15.2 0.1 0.6 0.2 0.0 18.7 0.1 1.7 4.1 0.0 2.5 4.0 2.6 17.1 0.8 0.3 0.1 0.1 49.0 19.9 28.6 7.7 0.2 48.3 1.3 19.7 0.0 0.9 20.1 4.8 0.3 0.4 0.3 8.0 0.3 9.1 1.0 0.3 11.6 0.3 0.1 0.8 0.2 106.7 0.1 34.0 1.6 4.5 23.8 5.1 0.5 44.1 1.1 312.7 0.5 0.5 89.9 415.7 1.3 1.1 11.0 8.4 33.7 899.0 1.1 11.4 31.4 34.7 10.5 47.8 38.7 15.5 31.6 15.3 31.0 15.9 15.9 38.7 0.6 0.0 7.4 3.6 149.0 46.3 16.0 34.0 118.4 2.5 31.6 28.6 18.2 4.3 11.7 1.8 0.0 0.6 140.3 7.5 5.9 9.5 12.0 3.9 2.0 1.4 19.8 69.6 180.8 6.4 0.5 3.6 5.1 4.8 10.1 67.4 0.7 0.1 43.2 52.2 153.2 13.6 6.1 7.0 86.1 5.0 0.3 20.5 16.0 11.2 16.0 0.3 0.0 3.5 4.6 4.7 12.5 0.0 6.0 11.7 16.2 0.5 5.5 0.3 0.0 0.2 2.0 2.9 6.9 120.3 69.9 0.8 4.6 1.0 28.9 5.8 BCO2 "B-DIOX-II, BCDO2, FLJ34464" ENSG00000197580 "Beta-carotene oxygenase 2" Q9BYV7 11 112175510-112224699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 47.2;liver: 52.3;retina: 55.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 410.8;Horizontal cells: 134.6;Rod photoreceptor cells: 254.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.9;HHSteC: 12.3;U-937: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061542 Supported NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA061542: " "unprognostic (2.92e-1)" "unprognostic (1.89e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-2)" "unprognostic (7.60e-3)" "unprognostic (1.88e-1)" "unprognostic (3.18e-2)" "unprognostic (6.40e-2)" "unprognostic (2.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.36e-4)" "unprognostic (2.31e-2)" "unprognostic (9.86e-2)" "unprognostic (1.07e-2)" "unprognostic (1.34e-1)" 3.8 21.3 4.9 0.3 5.8 0.2 0.8 5.0 9.3 2.2 10.0 2.6 0.5 1.6 1.0 3.4 9.7 5.1 47.2 4.8 6.4 2.5 52.3 1.7 0.4 7.4 6.7 1.3 1.1 0.3 4.4 3.8 7.0 1.9 0.5 55.9 0.9 0.9 21.4 1.1 1.7 1.1 5.9 1.1 0.9 3.0 6.5 0.3 2.5 14.3 0.8 2.3 4.6 8.3 0.1 1.0 0.4 0.6 0.4 0.4 0.0 0.3 0.2 0.1 0.5 0.0 5.9 0.4 0.5 0.6 0.6 1.2 0.0 0.2 0.4 0.1 0.1 0.7 0.5 0.4 12.3 0.4 0.2 0.1 2.3 0.1 0.3 1.1 0.0 0.1 0.1 0.3 0.1 0.0 0.5 1.3 0.1 0.6 0.2 0.3 0.1 0.2 0.2 0.2 0.5 0.2 0.4 0.2 0.0 0.1 0.3 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.0 2.6 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 4.9 5.8 5.0 9.3 4.8 6.4 7.4 6.7 7.0 5.9 6.5 8.3 1.7 3.2 3.1 10.1 2.0 3.3 20.3 8.6 6.8 12.6 2.2 1.5 51.3 58.6 8.2 5.5 410.8 0.3 4.4 5.0 0.0 3.7 3.1 26.5 3.0 4.5 8.3 0.0 50.7 2.1 0.4 16.3 1.1 1.2 5.7 4.0 16.4 83.1 1.0 134.6 51.5 1.6 2.0 2.8 3.8 2.4 4.1 7.9 1.8 47.8 3.7 13.9 7.2 7.1 51.3 1.6 2.6 3.8 1.2 10.3 18.2 1.3 67.6 254.6 0.0 5.0 3.8 8.3 2.5 1.8 3.1 0.7 5.2 6.8 3.5 8.7 BEX3 "Bex, DXS6984E, HGR74, NADE, NGFRAP1" ENSG00000166681 "Brain expressed X-linked 3" Q00994 X 103376395-103378164 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1607.8;Distal tubular cells: 1453.7;Granulosa cells: 700.3;Proximal tubular cells: 688.0;Syncytiotrophoblasts: 804.2;Theca cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 150.9;T-reg: 137.1" "Lineage enriched" "Detected in all" 5 "T-cells: 150.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018886 Approved Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA018886: AB_1854453" "unprognostic (7.74e-2)" "unprognostic (6.56e-2)" "unprognostic (8.15e-3)" "prognostic unfavorable (7.23e-5)" "unprognostic (2.70e-1)" "unprognostic (1.93e-3)" "unprognostic (7.15e-2)" "unprognostic (2.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.10e-2)" "unprognostic (3.85e-3)" "unprognostic (2.00e-1)" "prognostic favorable (1.28e-4)" "prognostic unfavorable (3.48e-4)" "unprognostic (1.38e-1)" "unprognostic (3.32e-2)" "unprognostic (8.68e-2)" 106.8 345.8 382.4 39.6 395.3 31.1 111.0 353.0 432.9 144.6 462.7 123.4 31.2 149.1 499.4 72.8 150.9 77.1 244.7 401.5 491.6 263.6 92.8 116.8 29.3 368.8 392.1 463.7 120.0 231.1 373.7 207.0 384.1 166.7 53.0 135.9 99.5 224.9 19.8 61.6 56.3 116.5 364.9 97.3 94.6 139.9 419.3 97.0 274.6 44.5 28.4 107.8 104.6 365.7 218.5 305.3 561.5 222.3 508.5 567.3 256.6 244.7 409.8 299.5 475.0 317.9 238.1 0.3 427.8 288.7 222.0 85.3 394.1 302.5 299.4 0.8 280.6 98.7 502.9 87.4 396.2 0.8 37.4 613.4 252.2 397.3 348.0 533.6 469.5 225.0 0.1 1.0 542.2 486.1 227.2 2.7 750.5 0.1 232.3 0.4 350.3 0.5 317.9 365.3 377.3 391.4 264.7 3.2 380.3 359.8 142.4 31.8 291.5 191.6 123.3 374.6 110.0 2.2 1.0 1.6 395.3 0.3 189.1 0.3 3.7 1.1 4.1 0.9 2.2 4.6 71.8 19.1 6.4 1.2 150.9 70.8 13.9 28.9 0.8 14.5 137.1 66.5 382.4 395.3 353.0 432.9 401.5 491.6 368.8 392.1 384.1 364.9 419.3 365.7 118.5 326.9 227.7 0.0 12.6 0.0 0.0 0.0 0.0 0.0 217.4 433.2 0.0 0.0 104.0 518.6 0.0 1607.8 4.7 0.0 1453.7 201.3 0.0 187.0 284.8 132.3 0.0 0.0 0.0 70.9 471.7 189.2 0.0 144.1 16.4 700.3 0.0 0.0 172.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 1.7 0.0 0.0 688.0 23.3 0.0 0.0 0.0 117.8 0.0 0.0 0.0 0.0 804.2 12.8 696.8 0.0 0.0 BMP7 OP-1 ENSG00000101144 "Bone morphogenetic protein 7" P18075 20 57168753-57266641 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;choroid plexus: 43.8;thyroid gland: 45.9" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Basal squamous epithelial cells: 51.8;Cytotrophoblasts: 137.4;Oligodendrocyte precursor cells: 74.4;Squamous epithelial cells: 44.2;Syncytiotrophoblasts: 56.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 172.1;MCF7: 202.3;OE19: 94.4;RPMI-8226: 77.8;SK-BR-3: 128.4;U-698: 237.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057757 Approved Nucleoplasm,Nucleoli,Vesicles "Secreted to blood" NA NA 248000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA057757: AB_2683518" "unprognostic (1.67e-1)" "unprognostic (9.72e-3)" "unprognostic (9.67e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.62e-1)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (4.63e-3)" "unprognostic (4.03e-2)" "unprognostic (1.09e-2)" "unprognostic (3.82e-2)" "unprognostic (4.30e-2)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (1.59e-1)" 1.5 6.5 33.1 1.9 34.6 0.0 1.3 37.2 27.9 8.5 43.8 2.9 2.2 1.2 17.2 23.9 9.5 0.4 13.8 35.6 28.5 6.3 0.0 1.6 1.0 36.2 36.3 0.2 0.5 0.0 2.7 25.7 34.7 5.9 1.7 5.3 3.9 9.2 0.3 22.5 1.9 0.3 32.8 0.6 3.6 0.7 39.7 3.8 45.9 0.0 2.1 6.8 13.0 42.8 0.3 0.7 23.4 5.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 20.0 6.8 172.1 41.3 0.0 8.7 48.3 5.2 0.0 0.0 0.4 17.2 0.1 0.0 0.0 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 202.3 0.0 0.1 12.3 94.4 0.0 0.1 0.1 77.8 0.0 0.2 0.4 17.8 5.5 128.4 0.5 15.2 0.9 0.4 0.4 0.1 10.9 0.0 0.1 0.2 0.3 237.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 34.6 37.2 27.9 35.6 28.5 36.2 36.3 34.7 32.8 39.7 42.8 0.6 6.4 2.2 74.1 0.4 13.8 13.4 12.9 51.8 4.7 0.9 4.6 15.1 0.0 4.2 1.8 0.0 137.4 0.1 0.2 0.0 0.0 5.3 1.7 2.4 1.2 2.4 0.0 0.9 0.0 21.0 13.5 2.0 2.5 21.6 0.1 0.0 0.0 11.0 1.7 4.7 1.5 6.1 0.0 1.9 4.9 0.3 0.4 3.6 2.8 0.1 38.4 0.0 74.4 8.7 0.0 0.3 0.4 2.5 6.6 0.2 2.2 1.9 2.4 0.0 1.3 0.8 1.8 3.4 44.2 9.7 56.9 0.9 0.7 1.5 18.1 BOLA3 ENSG00000163170 "BolA family member 3" Q53S33 2 74135400-74147912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 173.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 313.2;Distal tubular cells: 352.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046393, HPA053162" Uncertain Supported "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear bodies, Mitochondria" Cytosol "HPA046393: , HPA053162: AB_2682063" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-2)" "unprognostic (4.23e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.86e-3)" "unprognostic (8.03e-2)" "unprognostic (1.60e-2)" "unprognostic (4.03e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (9.90e-5)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (4.40e-1)" 35.6 39.3 52.1 22.6 54.3 40.8 31.4 58.9 66.1 20.2 55.0 46.5 33.8 24.5 25.1 31.7 20.8 11.9 101.0 52.7 56.5 59.8 33.7 23.5 22.2 57.0 53.8 16.6 44.7 56.2 29.6 14.2 56.0 25.4 37.6 35.7 39.7 23.7 117.8 16.6 28.9 22.6 54.7 21.9 41.1 15.8 53.7 24.8 28.8 173.9 21.6 27.1 24.3 55.3 102.8 134.0 44.8 46.2 81.5 78.3 113.9 92.5 54.5 104.0 72.0 176.6 45.4 67.2 79.7 82.4 99.3 53.2 107.9 135.4 95.8 126.5 172.8 85.4 88.3 269.8 76.1 167.3 39.0 62.2 96.6 100.9 124.2 45.9 79.4 144.3 183.2 73.7 116.0 163.6 136.4 123.1 66.9 196.8 198.6 88.5 120.1 132.0 138.8 106.2 70.4 40.7 68.3 106.8 123.3 62.0 62.6 102.8 42.6 83.9 142.9 93.8 185.4 67.5 135.3 92.7 87.6 131.8 73.8 14.7 14.2 3.9 68.3 29.9 75.7 45.4 92.7 72.6 37.8 44.5 79.3 68.7 3.0 51.7 33.5 65.1 91.2 40.6 52.1 54.3 58.9 66.1 52.7 56.5 57.0 53.8 56.0 54.7 53.7 55.3 54.7 9.6 29.8 8.5 33.2 22.7 44.5 111.8 43.3 29.9 82.0 109.5 313.2 44.3 50.1 84.6 16.7 54.9 42.8 125.4 352.1 93.2 20.0 67.0 46.2 45.5 76.1 138.2 14.3 111.4 167.5 48.6 58.1 61.5 25.4 31.9 36.4 113.3 113.9 26.9 15.0 128.3 83.4 32.1 28.9 10.2 32.9 32.2 99.6 3.7 59.4 61.8 62.8 7.5 7.7 95.0 70.9 46.3 76.1 50.9 85.6 266.4 51.2 52.6 19.7 39.6 64.4 66.8 80.5 101.0 16.9 22.3 45.1 83.0 176.2 52.0 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 C11orf1 FLJ23499 ENSG00000137720 "Chromosome 11 open reading frame 1" Q9H5F2 11 111878935-111885975 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 402.4;Late spermatids: 1147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038410, HPA057519" Uncertain Enhanced Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA038410: AB_10672591, HPA057519: AB_2683454" "unprognostic (1.33e-2)" "unprognostic (1.61e-1)" "unprognostic (1.96e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.30e-1)" "unprognostic (1.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-1)" "unprognostic (9.26e-2)" "unprognostic (3.23e-2)" "unprognostic (1.41e-2)" "unprognostic (2.86e-2)" "prognostic favorable (1.39e-4)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.97e-1)" "unprognostic (2.08e-1)" 21.5 37.0 25.9 10.4 29.0 18.1 49.2 26.4 36.1 20.5 24.6 26.3 20.4 17.2 64.2 24.0 28.6 19.6 33.0 26.1 27.5 70.3 54.9 16.3 15.1 26.1 26.7 28.0 48.0 39.9 28.4 9.4 26.5 27.4 26.4 22.3 33.0 26.8 16.2 34.8 21.4 14.9 25.7 11.6 30.6 61.2 27.1 20.3 41.1 21.1 17.8 22.7 18.4 27.0 25.1 31.9 40.3 44.6 45.6 34.3 42.0 13.5 34.2 10.9 13.8 54.5 45.6 91.9 63.5 23.2 31.4 28.9 16.5 50.2 17.0 40.6 23.4 30.9 6.9 42.0 28.6 45.7 20.9 63.8 76.9 39.0 74.4 48.4 13.5 96.2 45.3 66.8 36.9 25.0 62.2 70.8 46.3 86.8 48.0 31.5 42.0 127.6 69.4 46.0 36.3 34.1 8.7 31.5 31.3 38.4 63.1 31.8 11.7 40.2 28.8 17.6 19.1 38.8 61.2 136.7 20.3 53.1 24.9 6.5 7.4 9.0 13.0 14.6 24.9 26.0 22.0 17.0 11.1 17.7 34.5 26.5 1.7 16.7 10.1 32.8 17.6 10.2 25.9 29.0 26.4 36.1 26.1 27.5 26.1 26.7 26.5 25.7 27.1 27.0 14.3 25.6 19.8 3.6 22.6 23.7 67.5 60.6 71.2 8.6 56.5 79.6 57.6 28.6 43.4 35.0 6.2 28.9 17.3 15.1 201.5 21.8 402.4 30.5 17.3 15.3 26.4 26.3 3.5 27.2 22.5 16.5 22.4 22.6 29.2 23.3 11.0 43.4 23.0 15.2 4.7 39.8 28.5 7.9 11.4 1147.2 27.4 14.3 24.9 3.7 19.3 43.5 20.6 1.0 3.7 18.9 22.3 24.5 41.9 36.4 40.6 197.9 44.4 15.5 19.7 10.8 17.0 54.4 30.9 53.4 29.5 21.1 22.6 49.2 44.4 72.7 C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 50.4;heart muscle: 20.0;lymphoid tissue: 14.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 68.1;dendritic cells: 29.4;Macrophages: 20.3;monocytes: 28.4;NK-cells: 47.4;T-cells: 16.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 51.7;HL-60: 19.7;NB-4: 18.4;THP-1: 12.7;U-937: 22.2" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA037607: AB_10672909" "unprognostic (5.25e-3)" "unprognostic (2.65e-4)" "unprognostic (1.35e-1)" "unprognostic (4.61e-3)" "unprognostic (4.32e-2)" "unprognostic (3.58e-4)" "unprognostic (8.98e-4)" "unprognostic (2.37e-3)" "unprognostic (1.87e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.84e-4)" "unprognostic (8.50e-2)" "unprognostic (9.54e-2)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" 1.4 0.6 0.3 7.1 0.4 50.4 0.6 0.4 0.4 1.6 0.2 0.9 0.6 0.6 0.3 0.6 0.7 2.1 20.0 0.3 0.3 0.7 1.3 4.7 14.0 1.1 0.5 0.2 0.4 0.1 0.3 0.6 0.8 0.6 1.3 0.0 1.5 0.4 1.0 1.3 3.5 1.0 0.6 14.9 2.6 0.3 0.4 3.6 0.9 0.2 7.3 1.1 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 51.7 0.1 0.1 0.5 19.7 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.4 22.2 0.0 80.3 14.9 45.8 23.8 31.4 16.1 4.7 7.8 18.8 17.1 5.8 11.6 16.3 12.6 23.9 58.4 1.7 6.1 16.5 0.3 0.4 0.4 0.4 0.3 0.3 1.1 0.5 0.8 0.6 0.4 1.0 0.2 0.0 4.2 0.0 6.9 0.4 0.0 0.0 0.0 0.0 0.1 0.3 68.1 2.8 0.0 0.0 0.0 0.1 29.4 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 13.9 0.0 0.0 0.2 1.7 0.5 0.0 15.8 0.0 2.5 0.0 3.7 0.0 0.0 0.0 0.0 12.5 15.5 0.0 0.0 20.3 1.8 0.0 28.4 0.0 47.4 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.4 0.0 16.0 0.0 0.0 0.0 C11orf45 "FLJ43646, MGC35558" ENSG00000174370 "Chromosome 11 open reading frame 45" Q8TAV5 11 128899565-128906035 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.7;Hofbauer cells: 8.7;Kupffer cells: 5.9;Late spermatids: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.2;U-937: 8.9" HPA039716 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA039716: AB_10672892" "unprognostic (8.32e-2)" "unprognostic (3.93e-2)" "unprognostic (5.99e-3)" "unprognostic (1.35e-3)" "unprognostic (1.01e-1)" "unprognostic (9.93e-2)" "unprognostic (4.50e-5)" "unprognostic (1.97e-2)" "unprognostic (4.78e-2)" "unprognostic (3.10e-1)" "unprognostic (2.80e-1)" "unprognostic (9.27e-2)" "unprognostic (2.55e-9)" "unprognostic (2.37e-1)" "unprognostic (2.60e-2)" "unprognostic (6.87e-2)" "unprognostic (7.22e-2)" 0.6 3.3 1.7 0.7 4.4 0.8 0.9 0.6 2.1 1.0 0.8 0.7 1.4 0.5 0.6 2.9 1.0 2.0 4.5 1.4 1.6 2.0 0.5 2.6 0.8 1.9 1.9 0.9 2.6 3.8 2.3 2.1 1.6 1.1 0.9 0.2 1.6 2.8 0.1 6.6 0.9 0.5 1.1 1.5 1.8 1.1 2.3 2.4 1.8 0.2 0.9 1.2 1.3 2.2 2.4 4.5 0.0 0.0 0.3 0.4 1.6 0.8 4.7 1.7 4.2 6.3 5.8 0.0 3.2 0.5 4.2 2.3 2.4 11.2 0.8 0.0 1.1 0.3 2.7 0.0 0.2 0.0 0.0 0.3 1.5 1.3 0.9 3.8 1.0 3.5 0.0 0.2 2.0 1.2 2.6 2.4 1.8 1.0 3.9 1.1 4.6 0.5 3.9 1.1 0.0 0.2 1.8 5.0 0.3 1.2 0.8 4.4 0.5 0.0 6.2 0.0 0.8 0.1 0.0 0.0 0.8 8.9 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.9 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.7 4.4 0.6 2.1 1.4 1.6 1.9 1.9 1.6 1.1 2.3 2.2 0.1 0.0 0.5 0.0 0.0 2.8 1.3 0.9 5.7 0.0 0.3 0.4 1.7 0.0 0.2 0.0 0.0 2.0 0.0 0.1 1.9 1.0 2.0 0.3 0.1 0.2 0.0 0.0 0.3 0.8 2.1 0.3 0.0 0.5 1.3 0.3 0.4 0.0 8.7 0.0 0.2 0.1 0.0 5.9 0.8 8.2 0.0 2.2 0.0 2.8 0.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 1.5 1.7 3.0 0.9 1.2 0.2 0.1 0.2 1.1 C15orf61 LOC145853 ENSG00000189227 "Chromosome 15 open reading frame 61" A6NNL5 15 67521131-67530146 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 23.7" "Cell type enhanced" "Detected in all" "Early spermatids: 222.6;Spermatocytes: 258.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062820 Approved Nucleoli,Vesicles,Cytosol "Secreted - unknown location" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Vesicles" Cytosol "HPA062820: AB_2684874" "unprognostic (1.35e-1)" "unprognostic (9.42e-3)" "unprognostic (2.11e-1)" "unprognostic (5.41e-2)" "unprognostic (2.40e-1)" "unprognostic (2.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.87e-3)" "unprognostic (8.95e-2)" "unprognostic (4.01e-2)" "unprognostic (1.04e-2)" "unprognostic (8.45e-2)" "prognostic favorable (5.31e-5)" "unprognostic (2.42e-2)" "unprognostic (9.78e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" 4.7 3.8 2.3 1.5 6.2 5.3 3.6 7.1 4.2 3.1 0.0 2.3 2.8 2.3 1.9 2.0 2.9 1.5 5.7 3.8 1.6 3.0 2.5 2.3 1.3 1.0 2.4 2.7 4.2 4.4 5.1 2.0 1.0 2.5 2.2 10.8 2.6 2.1 23.7 4.1 1.8 1.4 0.7 1.7 2.4 7.7 2.1 1.4 2.8 8.3 1.0 2.2 2.4 2.3 4.2 4.4 1.1 4.9 5.0 7.2 3.1 1.8 3.2 3.3 2.6 3.4 2.9 3.5 3.8 2.0 3.9 4.9 4.4 1.2 2.7 2.1 10.4 3.7 3.3 4.6 3.2 4.6 3.0 7.5 3.4 1.1 4.0 2.4 1.6 10.6 4.3 7.6 1.0 2.4 3.8 7.6 1.8 3.3 5.6 5.1 2.5 13.0 2.3 2.9 6.4 4.8 3.2 3.0 6.1 2.1 2.7 7.1 1.6 4.4 6.8 5.5 4.7 7.1 11.2 8.5 1.9 9.0 2.2 7.9 4.3 7.8 4.5 3.7 5.2 5.3 5.9 4.5 4.8 3.6 6.2 5.0 0.5 3.8 3.2 4.9 4.0 3.5 2.3 6.2 7.1 4.2 3.8 1.6 1.0 2.4 1.0 0.7 2.1 2.3 28.0 22.4 13.5 4.9 23.1 67.2 32.6 32.3 120.7 75.5 55.7 82.3 74.5 18.6 14.3 16.5 37.5 42.6 23.8 38.6 80.3 25.1 222.6 17.5 24.2 26.8 27.1 11.8 14.8 29.8 31.9 56.8 15.8 17.1 34.8 15.2 22.9 44.7 30.5 13.5 15.7 47.5 48.8 24.8 25.6 42.6 41.0 19.9 37.4 3.7 15.6 97.1 23.7 5.0 8.5 27.6 48.4 25.6 37.4 63.3 49.0 77.1 8.4 93.9 32.9 38.2 38.7 258.9 52.1 62.7 60.9 20.5 34.4 28.9 39.2 20.0 C1orf127 FLJ37118 ENSG00000175262 "Chromosome 1 open reading frame 127" 1 10946471-10982037 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 4.4;skeletal muscle: 16.5" "Cell type enriched" "Detected in some" 9 "Enteroendocrine cells: 20.4" "Cancer enriched" "Detected in single" 9 "pancreatic cancer: 2.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Lineage enhanced" "Detected in single" "dendritic cells: 1.3" "Cell line enriched" "Detected in single" 4 "THP-1: 2.6" "Not detected" "Not detected" HPA027654 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles, Cytosol" "HPA027654: AB_10611814" "unprognostic (1.82e-2)" "unprognostic (8.57e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.03e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-2)" "unprognostic (9.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.82e-2)" "unprognostic (8.47e-2)" "unprognostic (1.59e-2)" "unprognostic (3.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (4.03e-1)" 0.2 0.6 0.3 0.1 0.3 0.1 0.1 1.2 0.7 0.1 0.2 0.3 0.7 0.0 0.1 0.6 0.0 0.3 0.6 0.2 0.3 0.0 0.2 0.4 0.6 0.2 0.5 0.0 4.4 0.1 0.2 0.2 0.3 0.1 0.6 0.0 0.2 0.0 16.5 0.0 0.3 0.0 0.2 0.6 1.9 0.5 0.7 0.1 0.2 3.7 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.2 0.7 0.2 0.3 0.2 0.5 0.3 0.2 0.7 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.8 0.0 0.8 0.6 0.1 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1orf226 FLJ13137 ENSG00000239887 "Chromosome 1 open reading frame 226" A1L170 1 162378841-162386812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 21.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 29.2;Early spermatids: 22.7;Hepatocytes: 30.0;Late spermatids: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 14.0;HEL: 18.4;OE19: 16.0" "Low region specificity" "Detected in all" "HPA052251, HPA074060" Approved Approved Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA052251: AB_2681775, HPA074060: " "prognostic favorable (2.60e-4)" "unprognostic (1.30e-1)" "unprognostic (2.69e-2)" "unprognostic (1.59e-2)" "unprognostic (6.71e-3)" "unprognostic (9.80e-2)" "unprognostic (8.55e-2)" "unprognostic (1.65e-1)" "unprognostic (2.05e-1)" "unprognostic (4.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-3)" "prognostic favorable (4.44e-5)" "unprognostic (9.34e-3)" "unprognostic (1.06e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.13e-4)" 1.9 9.6 3.5 1.1 3.6 2.0 8.1 4.6 3.1 3.8 5.1 9.3 5.6 2.4 2.4 4.1 3.2 3.4 3.4 3.7 5.1 11.3 21.9 2.5 0.4 7.2 4.0 1.2 3.7 4.0 9.9 2.4 5.3 4.8 9.7 7.0 8.5 7.7 0.6 5.2 7.9 2.4 5.8 0.6 8.7 4.0 3.5 0.4 0.8 0.6 1.5 2.5 2.2 7.3 14.0 0.9 13.1 8.9 0.4 0.0 0.2 0.9 1.4 0.8 0.5 2.0 7.2 0.0 9.5 0.3 4.7 10.3 3.7 0.9 0.7 0.1 4.4 18.4 0.8 10.2 0.3 0.0 0.0 1.4 1.1 0.0 0.5 3.9 3.2 2.3 1.7 0.1 0.2 5.6 0.5 0.0 6.3 16.0 7.5 0.3 2.2 0.0 12.1 7.0 5.9 3.7 4.6 1.6 3.1 5.3 5.7 0.9 3.1 0.1 1.4 0.1 4.0 6.3 0.0 0.0 2.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 4.6 3.1 3.7 5.1 7.2 4.0 5.3 5.8 3.5 7.3 2.5 3.2 2.6 0.3 0.1 0.8 1.7 1.1 0.6 0.8 10.3 14.9 3.4 4.3 2.4 14.7 29.2 0.1 0.1 11.6 0.0 0.9 22.7 2.6 1.1 2.2 2.4 0.0 2.8 2.3 0.1 0.7 0.0 4.2 0.0 3.4 4.2 30.0 0.1 6.7 1.8 11.6 4.1 1.0 0.7 38.4 2.1 0.1 0.0 3.7 0.0 5.0 0.0 6.6 3.7 1.7 3.6 1.9 0.0 2.6 7.7 0.2 2.7 0.4 0.0 0.2 0.6 1.1 0.9 0.6 1.4 0.1 0.3 0.5 7.1 2.5 C1orf53 ENSG00000203724 "Chromosome 1 open reading frame 53" Q5VUE5 1 197902630-197907367 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 64.6;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.9" "Lineage enriched" "Detected in many" 4 "monocytes: 8.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065352 Approved Vesicles,Aggresome NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles Aggresome "HPA065352: AB_2685477" "prognostic favorable (1.63e-4)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (2.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.90e-3)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" "unprognostic (5.53e-3)" "unprognostic (9.85e-2)" "unprognostic (1.12e-1)" "unprognostic (8.58e-3)" "unprognostic (1.37e-1)" 1.7 9.4 2.6 0.5 2.1 0.8 1.4 1.9 3.6 1.5 5.1 2.8 1.8 1.0 3.1 3.0 0.9 0.8 6.7 2.7 2.2 5.1 15.1 1.9 0.5 2.3 2.6 2.3 2.7 0.4 5.0 0.8 2.1 1.4 1.3 0.5 2.3 0.4 3.7 0.9 1.9 0.8 1.8 1.6 1.8 3.1 3.3 0.3 2.7 1.4 0.3 1.2 1.5 2.5 4.4 6.0 0.4 2.1 3.7 10.5 3.3 7.5 5.4 6.2 3.1 5.4 3.7 8.5 11.8 8.5 1.4 2.0 2.2 1.4 0.6 2.7 15.8 5.0 3.7 8.6 1.0 11.2 6.8 7.1 4.8 1.9 0.8 5.0 2.2 1.8 1.4 2.1 4.7 7.9 0.6 10.1 4.7 6.9 8.7 1.1 3.4 3.1 10.1 6.9 18.4 14.4 9.5 1.6 3.2 2.3 4.5 4.3 5.1 7.2 8.0 10.2 5.2 3.6 2.6 2.2 5.2 3.6 9.0 0.0 2.7 0.0 0.3 8.9 0.0 0.0 0.1 0.6 2.1 0.1 0.3 0.3 0.0 0.0 4.4 0.6 0.1 0.9 2.6 2.1 1.9 3.6 2.7 2.2 2.3 2.6 2.1 1.8 3.3 2.5 0.5 9.6 10.6 0.3 1.6 2.5 4.1 13.1 4.0 2.2 16.3 20.8 11.7 18.6 15.1 22.0 0.0 18.9 0.3 14.8 19.6 9.9 15.7 16.2 6.7 2.0 7.8 4.8 2.0 13.8 10.2 5.5 4.1 12.1 1.3 8.6 2.2 64.6 9.5 3.3 1.5 12.6 14.2 4.1 1.8 2.7 14.0 4.7 8.8 0.0 2.6 11.5 4.1 1.0 0.8 9.3 8.8 10.5 6.0 6.7 10.8 25.8 12.2 3.9 0.0 1.4 6.1 8.6 4.5 12.4 2.8 11.8 1.1 55.8 16.6 5.7 C22orf39 MGC74441 ENSG00000242259 "Chromosome 22 open reading frame 39" Q6P5X5 22 19351368-19447711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 118.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073701 Approved "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA073701: AB_2686627" "unprognostic (4.97e-2)" "unprognostic (2.67e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.27e-2)" "unprognostic (6.53e-2)" "unprognostic (5.07e-2)" "unprognostic (1.95e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (1.45e-3)" "unprognostic (5.34e-3)" "prognostic favorable (1.44e-4)" "unprognostic (6.51e-2)" "unprognostic (2.92e-1)" "unprognostic (1.32e-2)" "unprognostic (5.32e-2)" 25.2 22.9 35.2 8.9 34.3 13.7 22.0 34.7 49.6 22.0 33.8 38.1 10.5 22.2 11.2 15.4 22.3 7.7 47.2 34.2 33.2 26.5 18.0 17.8 12.8 35.6 34.8 19.8 26.3 22.6 24.3 10.4 36.3 26.2 11.8 23.9 16.4 13.6 118.6 19.3 19.7 11.3 35.0 21.0 23.5 16.7 35.9 16.2 27.9 44.8 12.4 26.9 17.8 34.4 20.7 7.1 16.3 11.5 17.5 15.4 12.1 5.9 5.7 13.7 15.8 11.3 4.8 15.8 6.8 6.4 8.2 17.3 16.3 10.9 14.7 17.3 66.7 20.1 19.2 26.5 17.1 30.8 19.5 12.9 17.6 7.3 19.9 14.7 14.0 33.6 60.6 21.5 9.0 10.1 24.0 27.3 7.2 42.4 18.2 25.8 23.9 11.5 18.4 12.1 24.8 12.4 11.8 8.3 23.9 14.9 11.4 18.4 13.4 9.9 18.6 7.0 9.1 29.4 12.6 22.8 11.6 14.7 9.4 36.4 29.6 72.0 23.0 33.8 21.9 27.8 25.7 19.7 26.1 27.9 25.9 21.4 43.0 31.1 30.3 38.8 35.3 26.7 35.2 34.3 34.7 49.6 34.2 33.2 35.6 34.8 36.3 35.0 35.9 34.4 41.6 22.4 40.4 10.1 39.5 24.3 28.4 58.8 23.3 28.7 42.8 44.3 94.1 27.1 50.8 36.8 16.7 54.6 50.8 44.3 107.6 40.4 21.5 36.0 20.8 29.7 45.1 41.2 13.9 77.9 47.9 31.2 35.7 26.4 26.6 25.9 36.0 35.3 65.4 18.5 17.3 44.4 52.9 38.0 33.5 12.7 35.1 32.8 39.2 5.6 59.6 52.3 60.8 10.1 14.5 58.7 42.0 33.8 37.6 34.6 69.0 67.2 46.1 20.4 46.0 31.9 36.9 54.8 57.6 37.8 32.5 50.3 34.9 33.1 55.9 31.2 C3orf18 G20 ENSG00000088543 "Chromosome 3 open reading frame 18" Q9UK00 3 50558025-50571027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.3;Early spermatids: 54.2;Late spermatids: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;NK-cells: 2.0;T-cells: 6.3" "Cell line enhanced" "Detected in many" "HDLM-2: 48.8" "Group enriched" "Detected in all" 4 "cerebellum: 28.2;olfactory bulb: 27.5" "Low region specificity" "Detected in all" HPA012105 Approved Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA012105: AB_1845717" "unprognostic (9.29e-3)" "unprognostic (1.46e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (8.19e-2)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (1.05e-2)" "unprognostic (1.64e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-3)" "unprognostic (1.29e-2)" "prognostic favorable (2.80e-9)" "unprognostic (7.65e-2)" "unprognostic (4.49e-1)" "unprognostic (2.18e-1)" "unprognostic (1.59e-1)" 6.1 8.7 23.0 2.9 23.6 0.9 5.6 30.0 24.0 10.8 25.8 11.9 1.8 10.6 4.4 3.5 9.3 3.6 33.3 22.2 25.6 9.4 4.9 3.7 3.8 23.6 24.9 12.6 6.6 27.3 12.5 2.1 23.2 9.2 2.6 28.4 7.1 9.8 36.2 3.1 5.3 9.5 22.8 5.2 10.1 19.7 25.1 3.1 9.0 26.8 3.6 9.5 6.4 22.1 1.8 2.7 3.1 0.6 10.1 9.0 1.0 11.1 17.2 9.9 7.2 0.2 2.8 2.3 2.6 15.2 9.3 0.2 0.0 4.3 5.2 48.8 0.3 5.0 6.9 0.8 5.0 0.0 6.0 8.9 0.6 9.6 0.5 7.9 1.9 7.2 1.1 2.2 5.9 0.4 0.4 1.5 3.8 1.9 12.3 1.0 0.3 2.7 0.6 0.4 3.4 16.1 2.9 0.6 0.3 3.5 3.4 1.3 0.6 9.9 7.7 18.1 1.4 2.8 2.5 0.3 14.0 5.1 0.2 0.0 0.4 0.7 5.1 0.1 6.3 2.2 4.3 4.8 0.4 1.4 5.0 6.1 0.0 2.0 0.1 0.8 2.2 2.5 23.0 23.6 30.0 24.0 22.2 25.6 23.6 24.9 23.2 22.8 25.1 22.1 1.8 0.0 1.1 8.1 2.2 1.1 1.1 0.9 1.2 10.2 1.8 2.0 29.3 0.0 1.4 1.8 8.4 0.4 1.3 0.3 3.9 2.1 54.2 1.1 2.3 2.6 1.8 0.0 5.6 1.8 0.8 4.9 1.5 0.5 0.0 3.1 2.5 2.2 1.6 1.7 8.3 0.7 0.0 1.3 0.3 62.6 4.7 1.1 0.0 3.7 8.9 12.4 3.1 3.0 3.3 0.7 0.1 4.1 1.6 0.5 0.1 3.5 1.2 17.3 13.1 5.6 5.3 2.7 2.5 0.1 0.4 0.1 3.0 2.7 0.3 0.2 C9orf24 "bA573M23.4, CBE1, MGC32921, MGC33614, NYD-SP22, SMRP1" ENSG00000164972 "Chromosome 9 open reading frame 24" Q8NCR6 9 34379019-34397810 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 39.2;choroid plexus: 105.6;fallopian tube: 108.7;testis: 90.6" "Cell type enhanced" "Detected in many" "Early spermatids: 744.6;Endometrial ciliated cells: 841.0;Late spermatids: 3115.3;Respiratory ciliated cells: 1312.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053008 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Cytosol "HPA053008: AB_2682015" "unprognostic (3.62e-3)" "unprognostic (9.06e-3)" "unprognostic (1.00e-1)" "prognostic favorable (3.23e-5)" "unprognostic (7.66e-2)" "unprognostic (1.21e-2)" "unprognostic (2.40e-1)" "unprognostic (1.25e-1)" "unprognostic (2.72e-1)" "unprognostic (1.58e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.33e-1)" "unprognostic (6.39e-3)" "unprognostic (1.50e-1)" "unprognostic (7.43e-3)" "unprognostic (4.72e-2)" "unprognostic (1.90e-2)" 1.2 0.6 20.6 0.3 26.6 0.0 0.7 19.5 29.8 7.8 105.6 3.2 1.9 0.7 0.0 0.4 108.7 0.3 17.5 20.8 22.8 3.4 0.3 18.4 0.2 35.9 39.2 0.4 0.9 0.1 10.6 0.2 29.8 1.6 0.7 1.2 1.9 0.4 1.4 0.6 5.4 0.5 33.0 0.2 1.4 90.6 22.3 0.3 0.6 1.7 0.3 0.9 0.4 25.5 0.2 0.0 0.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.3 0.4 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.3 0.0 0.4 1.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.2 0.6 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.8 0.3 0.0 0.2 0.0 0.0 0.4 0.1 20.6 26.6 19.5 29.8 20.8 22.8 35.9 39.2 29.8 33.0 22.3 25.5 0.4 6.4 15.1 11.4 0.3 2.2 3.3 67.3 2.2 1.4 1.6 1.8 37.0 1.5 116.4 7.3 0.0 0.6 0.1 11.3 72.4 1.1 744.6 841.0 6.1 2.1 12.1 0.0 11.3 1.5 0.3 3.5 0.5 9.8 8.8 0.2 1.4 4.1 0.4 0.0 12.6 13.4 81.4 1.0 1.0 3115.3 10.5 2.7 0.0 1.0 0.0 2.2 1.0 4.0 5.4 0.2 7.3 7.2 0.5 4.5 142.5 13.7 1312.6 0.9 32.9 0.5 25.5 21.0 6.9 0.4 1.0 0.5 1.6 0.0 20.5 2.4 CACNA2D3 HSA272268 ENSG00000157445 "Calcium voltage-gated channel auxiliary subunit alpha2delta 3" Q8IZS8 3 54122547-55074557 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.8;skeletal muscle: 9.9;tongue: 10.7" "Cell type enhanced" "Detected in many" "Astrocytes: 160.9;Excitatory neurons: 828.3;Inhibitory neurons: 456.4;Oligodendrocyte precursor cells: 317.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.1;HAP1: 1.9;HeLa: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030849 Uncertain Nucleoplasm NA NA 69000 "Cluster 47: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA030849: " "unprognostic (6.92e-2)" "unprognostic (1.35e-2)" "unprognostic (1.89e-1)" "unprognostic (4.34e-5)" "unprognostic (5.53e-3)" "unprognostic (2.64e-3)" "unprognostic (3.24e-1)" "unprognostic (1.17e-2)" "unprognostic (5.84e-3)" "unprognostic (7.22e-3)" "unprognostic (1.14e-2)" "unprognostic (2.43e-1)" "unprognostic (2.00e-1)" "unprognostic (1.47e-3)" "unprognostic (2.19e-1)" "unprognostic (3.62e-2)" "unprognostic (6.95e-2)" 0.2 4.1 8.8 0.1 11.6 0.0 0.2 0.0 15.8 0.3 0.0 0.7 0.1 0.1 1.3 0.5 0.4 0.2 2.6 9.4 8.4 1.3 0.0 0.5 0.5 2.1 10.2 2.5 0.0 0.3 0.8 0.5 1.3 1.0 0.3 2.9 0.4 1.5 9.9 0.1 0.3 0.6 0.0 0.2 0.4 1.4 3.5 0.1 0.4 10.7 0.5 0.1 0.4 9.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.1 0.1 9.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 11.6 0.0 15.8 9.4 8.4 2.1 10.2 1.3 0.0 3.5 9.9 0.5 0.0 0.0 160.9 0.6 0.3 0.4 0.2 7.4 10.8 0.2 0.5 30.2 0.0 0.7 0.0 8.4 9.9 5.5 0.1 7.9 0.0 83.4 0.9 0.8 0.6 0.0 1.3 828.3 0.6 3.2 3.4 1.5 1.8 0.0 1.1 0.4 0.0 5.9 0.0 456.4 0.0 2.0 8.9 2.7 56.1 2.8 11.0 0.0 97.4 22.2 5.0 0.0 317.7 11.3 1.2 0.0 1.5 0.1 0.4 0.0 0.2 0.8 1.4 6.6 1.7 1.9 5.7 2.9 3.4 0.1 68.0 0.7 0.8 0.0 0.4 CACNB2 "CACNLB2, MYSB" ENSG00000165995 "Calcium voltage-gated channel auxiliary subunit beta 2" Q08289 10 18140424-18543557 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.1" "Group enriched" "Detected in many" 5 "Astrocytes: 863.5;Excitatory neurons: 545.7;Inhibitory neurons: 357.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HAP1: 6.4;HSkMC: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035326 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA035326: AB_10669903" "unprognostic (3.03e-3)" "unprognostic (3.04e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (4.58e-3)" "unprognostic (4.67e-4)" "unprognostic (8.03e-2)" "unprognostic (3.76e-2)" "unprognostic (8.10e-2)" "unprognostic (1.70e-1)" "unprognostic (7.78e-4)" "unprognostic (1.40e-1)" "prognostic favorable (3.56e-5)" "unprognostic (3.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.03e-1)" "unprognostic (8.16e-2)" 2.8 9.4 1.3 2.1 3.9 1.3 3.8 5.4 12.9 7.4 0.1 17.6 1.1 12.8 2.7 5.0 10.1 2.2 17.8 5.4 7.4 3.2 10.7 3.9 0.9 0.0 0.1 13.6 7.5 0.6 19.3 0.5 0.0 8.5 3.2 35.1 3.9 8.8 1.1 4.2 11.4 5.3 0.0 1.5 7.7 2.1 2.2 0.7 2.5 0.7 0.2 16.8 4.6 1.5 0.2 1.0 0.7 0.5 0.3 0.3 0.5 0.3 0.0 0.0 0.3 0.4 0.5 0.9 0.2 0.2 0.3 0.7 6.4 0.0 0.0 0.3 2.4 0.8 1.7 1.5 1.6 0.5 1.5 8.1 0.0 0.0 0.0 0.3 0.0 1.4 0.9 1.6 0.0 0.7 0.8 1.0 2.4 0.0 0.0 0.7 0.7 0.8 0.0 0.8 2.9 0.8 0.1 0.0 0.4 0.8 0.1 0.9 0.0 0.6 1.5 0.3 0.6 1.6 1.8 1.7 0.2 1.2 0.3 1.4 0.1 0.2 0.2 0.2 0.4 0.4 0.3 0.1 0.0 0.5 0.5 0.8 0.1 0.3 0.2 0.2 1.1 0.0 1.3 3.9 5.4 12.9 5.4 7.4 0.0 0.1 0.0 0.0 2.2 1.5 2.1 0.0 0.6 863.5 0.1 3.3 1.3 0.0 1.8 31.9 1.1 1.3 22.4 0.0 0.0 0.0 108.4 0.4 0.7 2.8 1.9 0.4 0.9 1.1 13.9 1.5 37.1 0.8 545.7 0.2 0.0 3.0 0.0 2.6 0.0 3.8 0.0 0.9 0.1 8.4 357.8 9.4 0.0 0.0 1.1 0.8 0.9 0.5 1.8 96.5 0.0 15.9 0.0 95.5 13.7 0.2 2.4 4.5 0.3 2.1 5.9 0.8 0.0 75.7 6.6 2.6 14.2 0.1 0.1 0.0 4.1 0.3 1.0 5.3 5.7 1.3 CAMK2A "CAMKA, CaMKIIα, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 662.9" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 245.8" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Region enhanced" "Detected in many" "cerebral cortex: 662.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;SCLC-21H: 3.0;SuSa: 1.4;U-87 MG: 3.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 1071.1" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 66000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 0.2 0.9 161.7 0.2 230.9 0.1 0.1 0.0 662.9 1.2 0.0 1.0 0.1 2.8 0.3 1.3 1.5 0.3 4.8 453.1 0.0 0.7 0.2 0.9 0.0 0.0 0.0 0.4 0.1 0.0 3.5 0.3 0.0 0.8 0.2 1.9 0.7 0.4 95.0 0.7 0.4 2.4 0.0 0.3 0.5 0.1 0.0 0.0 0.1 34.7 0.0 2.0 0.7 99.6 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.8 0.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.9 0.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.7 230.9 0.0 662.9 453.1 0.0 0.0 0.0 0.0 0.0 0.0 99.6 0.0 0.0 0.0 12.1 0.0 3.4 0.0 0.0 0.0 5.1 0.0 0.0 14.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.2 0.0 0.0 245.8 0.0 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.0 55.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 3.6 9.4 0.0 0.4 0.0 8.5 8.1 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.1 0.0 3.6 1.8 0.0 0.3 0.0 1.4 0.3 0.2 0.0 0.0 0.0 CAND2 "KIAA0667, TIP120B, Tp120b" ENSG00000144712 "Cullin associated and neddylation dissociated 2 (putative)" O75155 3 12796472-12871916 "Predicted intracellular proteins" "Transcription, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 135.0" "Cell type enriched" "Detected in many" 4 "Early spermatids: 120.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 19.4;REH: 12.4;U-266/84: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005777 Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" Cytosol "HPA005777: AB_2667431" "unprognostic (6.11e-3)" "unprognostic (3.44e-2)" "unprognostic (1.52e-3)" "unprognostic (6.09e-2)" "unprognostic (4.22e-1)" "unprognostic (2.35e-1)" "unprognostic (1.12e-2)" "unprognostic (1.67e-2)" "unprognostic (2.00e-2)" "unprognostic (9.03e-2)" "unprognostic (6.36e-3)" "unprognostic (1.03e-1)" "unprognostic (4.78e-5)" "unprognostic (1.31e-2)" "unprognostic (2.21e-2)" "unprognostic (1.75e-1)" "unprognostic (2.96e-3)" 3.0 3.2 7.9 0.5 7.9 1.0 1.9 6.4 8.7 4.8 7.6 6.5 0.9 6.4 2.2 2.4 6.2 1.7 25.3 8.0 9.6 2.4 1.6 2.4 0.8 8.0 7.4 5.0 2.4 5.4 8.3 0.8 8.3 3.6 0.7 2.2 3.3 3.0 135.0 1.4 2.3 3.4 6.6 2.2 3.3 15.7 8.8 0.8 3.1 36.2 0.6 4.4 2.7 8.6 0.8 1.6 5.6 0.2 0.2 0.1 0.3 1.4 0.6 3.4 4.1 0.9 0.3 1.0 1.9 0.9 0.9 0.2 6.4 0.1 2.6 1.8 19.4 1.5 2.9 1.4 5.2 0.2 0.1 1.2 0.3 3.1 0.1 3.3 0.7 7.2 5.3 1.0 1.0 3.3 2.6 0.8 3.8 0.4 2.0 12.4 1.2 1.0 0.2 1.5 3.9 4.6 0.1 0.9 1.2 1.1 1.6 6.3 0.4 1.0 0.9 1.0 1.4 1.3 9.9 8.4 0.6 1.2 2.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.1 7.9 7.9 6.4 8.7 8.0 9.6 8.0 7.4 8.3 6.6 8.8 8.6 0.9 3.2 1.1 5.9 0.2 0.4 0.8 0.6 1.8 16.0 0.4 0.5 4.8 1.5 0.7 1.8 10.4 0.2 0.2 0.1 0.0 0.9 120.6 0.4 1.4 1.8 0.0 0.4 19.3 0.0 0.2 2.6 0.5 0.3 0.0 5.6 3.3 2.0 4.2 13.5 25.3 0.0 0.0 0.0 0.8 23.2 4.7 0.4 0.0 4.7 0.0 2.9 1.0 12.1 7.2 0.0 0.0 10.1 0.2 0.5 0.0 0.7 0.3 3.1 0.0 4.1 4.0 1.4 5.3 0.4 0.1 0.1 1.0 9.2 0.0 0.4 CAPN9 "GC36, nCL-4" ENSG00000135773 "Calpain 9" O14815 1 230747384-230802003 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 22.2;stomach 1: 60.3" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 25.6;Gastric mucus-secreting cells: 93.8;Intestinal goblet cells: 71.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "OE19: 10.7;SCLC-21H: 14.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020398, CAB033483, HPA062050" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 4: Stomach - Digestion" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Golgi apparatus" "CAB033483: AB_1119945, HPA020398: AB_2670429, HPA062050: " "unprognostic (2.64e-1)" "unprognostic (1.20e-1)" "unprognostic (2.60e-2)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.49e-2)" "unprognostic (3.36e-2)" "unprognostic (2.30e-2)" "unprognostic (4.61e-2)" "unprognostic (3.44e-2)" "unprognostic (9.10e-2)" "unprognostic (1.60e-1)" "unprognostic (5.97e-5)" "unprognostic (1.51e-1)" "unprognostic (2.08e-1)" "unprognostic (4.60e-2)" "unprognostic (2.16e-1)" 0.0 0.6 1.4 0.9 2.2 0.0 0.4 1.3 1.2 0.4 0.0 13.7 6.6 0.2 0.5 0.2 2.5 0.6 0.4 1.1 1.4 0.0 0.0 7.5 0.0 2.1 1.7 0.6 0.2 1.0 0.0 0.0 1.8 0.6 22.2 5.0 11.3 0.1 0.2 0.1 11.7 0.5 1.9 0.0 60.3 0.2 1.7 0.1 0.1 0.1 0.0 2.0 0.1 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.1 0.0 0.5 10.7 0.0 0.4 0.0 0.0 0.0 0.1 14.7 0.0 0.0 0.4 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 1.3 1.2 1.1 1.4 2.1 1.7 1.8 1.9 1.7 3.4 0.0 25.6 3.0 0.3 0.1 0.0 0.6 0.7 0.0 0.0 0.6 0.3 6.0 0.0 3.2 0.0 0.0 0.1 0.0 4.1 0.0 0.2 5.2 1.5 0.1 0.1 3.0 0.0 0.4 0.2 0.0 0.4 93.8 0.5 2.5 0.1 0.0 0.0 0.1 0.0 0.4 71.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.6 1.7 5.0 0.0 0.2 0.5 3.3 0.1 8.2 1.7 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.1 1.5 CAPS2 ENSG00000180881 "Calcyphosine 2" Q9BXY5 12 75275979-75390928 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 11.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.5;Excitatory neurons: 133.8;Inhibitory neurons: 95.8;Oligodendrocyte precursor cells: 117.1;Oligodendrocytes: 102.6;Respiratory ciliated cells: 77.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039542, HPA040004" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Vesicles, Centrosome" "HPA039542: , HPA040004: AB_10794758" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" "unprognostic (7.26e-2)" "unprognostic (5.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.36e-1)" "unprognostic (9.61e-2)" "unprognostic (1.24e-1)" "unprognostic (2.02e-3)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (3.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.52e-2)" "unprognostic (2.69e-1)" 1.0 1.5 1.2 0.3 1.2 0.5 1.4 1.7 4.0 1.2 8.8 1.0 0.6 2.0 3.7 1.3 10.0 1.3 2.3 1.1 3.1 2.7 1.8 2.4 0.3 5.5 4.3 1.6 0.9 3.9 2.5 0.1 2.5 2.0 0.6 11.8 2.4 1.3 1.7 0.9 0.6 0.6 2.7 1.0 1.3 3.8 2.3 0.6 4.0 3.2 0.3 0.7 0.7 2.6 0.7 2.1 0.6 0.1 1.0 0.7 0.0 0.4 0.1 1.1 1.2 0.0 1.0 0.2 1.8 0.3 0.4 0.5 0.0 1.0 0.8 0.7 0.3 0.9 0.4 0.0 0.0 0.1 0.0 0.3 0.5 0.9 0.2 6.8 0.1 0.7 0.2 0.3 1.5 0.0 1.0 0.8 0.3 0.0 0.3 0.0 0.0 0.1 1.5 0.0 1.2 0.6 0.1 0.0 0.6 0.1 0.7 0.3 0.5 1.0 0.5 0.2 0.1 0.1 0.0 0.0 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.0 1.2 1.2 1.7 4.0 1.1 3.1 5.5 4.3 2.5 2.7 2.3 2.6 3.3 9.6 2.8 85.5 1.7 1.8 2.6 2.9 7.4 1.5 3.1 3.0 8.2 1.5 11.5 5.5 4.2 1.2 0.9 0.4 5.9 1.1 35.8 24.3 2.1 2.3 0.0 4.6 133.8 1.7 0.6 4.8 4.6 0.9 0.0 6.0 3.3 2.4 0.5 1.7 95.8 1.3 2.0 1.6 1.7 14.9 6.2 1.3 0.0 46.9 0.1 6.7 2.1 117.1 102.6 0.6 0.3 7.2 2.5 1.0 0.5 3.5 77.2 22.4 0.0 3.8 3.8 8.5 1.6 4.1 0.6 0.3 1.6 3.3 0.8 0.6 CARNS1 "ATPGD1, KIAA1394" ENSG00000172508 "Carnosine synthase 1" A5YM72 11 67414968-67425607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 278.3;skeletal muscle: 75.5" "Cell type enriched" "Detected in some" 19 "Oligodendrocytes: 447.9" "Group enriched" "Detected in many" 5 "glioma: 4.1;thyroid cancer: 10.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 12 "RPMI-8226: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA038569 Enhanced "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA038569: AB_2676089" "unprognostic (1.07e-4)" "unprognostic (4.33e-3)" "unprognostic (2.00e-2)" "unprognostic (6.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.05e-1)" "unprognostic (7.28e-2)" "unprognostic (7.54e-3)" "unprognostic (1.29e-1)" "unprognostic (1.82e-1)" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (6.14e-6)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (3.83e-3)" "unprognostic (8.33e-2)" 11.7 0.3 62.1 0.4 149.5 0.5 0.7 127.6 119.0 0.7 20.4 0.7 0.4 0.5 1.4 0.9 1.3 0.5 8.8 64.6 89.6 0.8 0.4 0.9 1.2 168.6 137.6 0.9 1.2 0.9 0.6 0.0 145.9 0.7 0.2 0.0 1.3 0.2 75.5 0.6 0.9 0.2 101.8 2.1 7.5 0.2 122.2 0.4 5.6 30.1 0.5 0.5 0.6 278.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.6 0.3 0.1 0.1 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.5 0.3 1.0 0.0 0.6 0.4 1.0 0.0 0.5 0.0 0.0 0.2 0.3 62.1 149.5 127.6 119.0 64.6 89.6 168.6 137.6 145.9 101.8 122.2 278.3 0.6 3.2 0.5 1.0 3.5 0.3 0.2 0.2 0.0 0.0 0.3 0.4 13.5 7.2 0.7 0.0 0.0 0.1 6.1 0.6 0.0 0.5 0.0 0.3 0.2 1.0 3.0 0.0 1.2 0.0 0.1 1.5 23.0 0.5 0.0 0.1 0.4 0.4 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 4.1 2.5 447.9 0.1 0.1 0.4 4.0 0.2 0.2 0.3 0.9 0.5 0.0 3.5 3.0 0.0 0.3 0.1 0.9 0.0 2.3 0.3 0.2 0.1 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CCDC141 "CAMDI, FLJ39502" ENSG00000163492 "Coiled-coil domain containing 141" Q6ZP82 2 178829757-179050086 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 74.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.5;Bipolar cells: 28.1;Cardiomyocytes: 118.2;Cholangiocytes: 27.1;Early spermatids: 37.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 15.0" "Group enriched" "Detected in many" 9 "B-cells: 8.1;T-cells: 15.0" "Cell line enhanced" "Detected in some" "CACO-2: 4.6;Daudi: 3.0;HEL: 6.9;RH-30: 3.6;U-266/70: 4.3;U-698: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012718 Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA012718: AB_2072055" "unprognostic (1.58e-1)" "unprognostic (1.85e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-1)" "unprognostic (8.62e-3)" "unprognostic (4.25e-2)" "unprognostic (2.98e-2)" "unprognostic (2.51e-1)" "unprognostic (1.40e-1)" "unprognostic (1.74e-2)" "unprognostic (5.33e-2)" "unprognostic (8.03e-3)" "unprognostic (7.71e-8)" "unprognostic (2.50e-2)" "unprognostic (1.52e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-1)" 1.5 0.3 0.8 0.5 0.4 1.3 0.7 0.9 1.0 0.6 0.8 0.2 0.1 0.6 0.2 0.4 0.4 1.7 74.6 0.3 0.6 0.1 0.3 2.0 1.5 1.2 1.1 1.0 5.8 0.1 0.0 1.2 1.4 0.3 0.2 1.1 0.1 0.2 17.1 0.5 0.2 0.2 1.6 0.7 0.2 1.5 1.0 1.5 0.3 3.5 1.1 0.3 0.1 1.8 0.1 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.1 4.6 0.3 3.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 6.9 0.2 0.0 0.0 1.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.1 0.0 0.1 0.2 2.4 0.4 0.5 0.1 3.6 1.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.7 0.2 0.3 0.0 0.2 0.1 0.2 0.0 4.3 0.1 6.1 0.2 0.3 0.4 0.4 0.0 0.2 0.3 0.0 0.2 7.3 2.2 1.5 0.0 8.1 6.5 5.1 0.3 1.2 0.0 0.0 15.0 0.4 0.8 0.4 0.9 1.0 0.3 0.6 1.2 1.1 1.4 1.6 1.0 1.8 4.5 6.4 29.5 5.5 11.0 0.1 0.0 0.0 0.6 28.1 0.2 0.3 118.2 27.1 0.6 0.0 0.0 0.0 2.8 0.1 0.0 4.6 37.3 0.2 1.1 6.7 0.0 0.4 3.6 1.3 0.2 2.9 0.0 1.1 6.3 0.0 0.4 0.3 0.0 6.7 3.1 0.1 0.0 1.0 1.0 16.8 1.2 3.9 1.8 8.4 0.1 5.5 1.0 0.5 0.8 0.2 0.0 1.9 2.6 0.0 0.2 0.1 1.5 0.6 6.6 2.8 5.4 0.1 1.1 0.0 0.1 0.0 10.3 1.1 0.2 0.2 CCDC28B "MGC1203, RP4-622L5.5" ENSG00000160050 "Coiled-coil domain containing 28B" Q9BUN5 1 32200595-32205453 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 225.3;tongue: 75.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 90.1;monocytes: 65.5;NK-cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebellum: 124.9" "Low region specificity" "Detected in all" HPA028589 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "HPA028589: AB_10602175" "prognostic favorable (2.92e-4)" "unprognostic (6.01e-3)" "unprognostic (1.04e-1)" "unprognostic (2.61e-2)" "unprognostic (2.59e-3)" "unprognostic (5.18e-2)" "unprognostic (7.50e-3)" "unprognostic (7.87e-2)" "unprognostic (5.15e-2)" "unprognostic (1.79e-2)" "prognostic favorable (1.10e-5)" "unprognostic (2.61e-2)" "unprognostic (1.22e-2)" "unprognostic (1.44e-2)" "unprognostic (1.67e-1)" "unprognostic (7.83e-2)" "unprognostic (1.07e-2)" 3.8 13.9 14.3 7.1 12.9 6.8 3.3 14.5 18.7 6.6 12.1 7.6 1.7 5.3 1.7 5.5 5.6 4.9 20.8 13.2 13.3 6.5 2.4 3.9 14.1 12.8 13.3 6.0 5.6 19.2 21.1 5.0 12.2 5.3 2.5 5.1 3.6 4.1 225.3 2.7 4.3 6.2 12.6 5.4 3.9 20.8 15.8 12.4 6.3 75.0 9.5 5.0 4.3 13.1 10.6 4.5 20.8 22.7 6.8 8.5 1.2 8.2 11.9 13.2 9.3 9.0 13.2 23.3 14.2 9.3 1.7 0.5 18.7 9.2 2.6 27.0 25.5 29.9 20.7 4.1 10.1 0.2 13.7 10.5 3.5 15.5 0.2 9.2 19.3 40.5 20.5 0.5 9.6 1.3 43.2 8.7 29.4 2.8 5.8 46.5 10.4 19.2 12.2 0.0 45.6 22.9 11.9 3.2 16.3 12.0 12.0 11.5 11.4 7.1 9.5 8.7 7.6 2.1 1.6 0.9 11.7 43.9 10.3 9.7 13.7 3.0 36.3 6.9 17.6 22.0 19.4 34.3 30.6 31.5 28.4 29.3 1.9 46.7 2.1 37.1 26.9 21.8 14.3 12.9 14.5 18.7 13.2 13.3 12.8 13.3 12.2 12.6 15.8 13.1 10.5 0.0 6.1 3.9 11.1 9.1 4.4 17.9 5.7 33.3 9.6 12.7 16.1 11.5 5.3 12.9 22.9 1.9 25.8 1.6 35.2 17.5 13.8 8.1 18.1 15.2 90.1 30.7 3.1 7.6 4.0 19.0 5.6 5.1 3.8 8.0 12.1 0.6 11.7 23.5 3.9 5.7 54.9 4.2 39.2 32.8 20.2 5.7 17.8 0.0 65.5 23.9 106.1 5.5 1.7 7.8 1.7 17.0 1.8 3.4 0.3 4.9 4.2 45.9 0.0 12.5 18.0 3.9 13.3 3.5 7.7 2.2 15.3 48.1 3.4 2.6 CCT6B "Cctz2, TSA303" ENSG00000132141 "Chaperonin containing TCP1 subunit 6B" Q92526 17 34927859-34981078 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "testis: 126.1" "Group enriched" "Detected in many" 27 "Early spermatids: 448.5;Late spermatids: 185.2;Spermatocytes: 490.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042996, HPA045576, HPA049949" Uncertain Approved Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA042996: AB_2678261, HPA045576: AB_2679372, HPA049949: AB_2680968" "unprognostic (1.56e-1)" "unprognostic (1.72e-2)" "unprognostic (2.99e-3)" "unprognostic (6.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.12e-3)" "unprognostic (3.61e-2)" "unprognostic (1.75e-1)" "unprognostic (1.44e-3)" "unprognostic (9.56e-3)" "unprognostic (3.61e-2)" "unprognostic (4.82e-7)" "unprognostic (1.24e-1)" "unprognostic (4.30e-1)" "unprognostic (4.23e-4)" "unprognostic (1.49e-1)" 2.9 3.3 1.9 0.8 2.3 3.8 5.5 2.0 2.7 2.2 1.6 1.7 1.4 1.9 5.5 1.8 2.7 0.9 1.7 1.7 2.0 4.0 5.0 1.2 1.4 2.2 2.1 2.4 2.6 2.5 2.7 0.6 2.3 2.7 1.1 2.3 3.3 2.6 5.1 2.7 1.4 1.6 2.3 1.6 2.0 126.1 2.0 1.6 2.9 3.8 1.7 1.9 1.5 2.7 0.7 1.0 2.6 1.1 3.3 2.0 0.9 1.3 5.3 2.2 3.1 0.7 2.1 5.0 0.5 2.4 1.6 1.0 0.1 0.7 0.7 0.5 1.9 0.7 0.3 0.6 4.5 2.4 0.7 2.7 1.3 0.2 2.6 0.4 0.6 0.8 0.5 5.0 2.4 1.9 0.5 5.2 1.4 0.4 0.6 2.4 1.2 12.2 1.4 0.8 3.0 1.5 2.4 0.9 4.1 0.6 1.9 2.4 0.5 1.0 0.1 1.2 0.6 4.4 1.0 4.7 1.1 1.5 1.3 0.0 1.1 0.9 0.6 1.1 0.6 0.9 0.7 0.4 2.6 0.8 1.0 1.0 0.0 1.6 1.1 0.6 0.3 0.6 1.9 2.3 2.0 2.7 1.7 2.0 2.2 2.1 2.3 2.3 2.0 2.7 2.4 0.0 3.1 4.6 2.6 2.4 2.8 3.2 6.2 1.5 8.7 7.0 4.2 4.3 3.9 1.8 0.0 1.8 4.0 0.9 3.9 3.4 448.5 8.8 3.7 2.1 0.0 0.8 3.9 8.0 0.5 3.5 1.5 3.6 2.5 4.6 0.7 3.1 1.5 0.0 3.7 2.3 6.1 2.2 4.0 185.2 10.8 2.9 5.4 4.7 1.6 8.7 4.1 7.1 10.7 2.7 1.6 4.1 3.9 2.1 0.7 6.9 8.8 2.5 0.0 3.7 3.0 490.2 13.5 3.1 2.6 0.8 2.7 6.9 1.8 3.6 CEP85 "CCDC21, DKFZP434L0117" ENSG00000130695 "Centrosomal protein 85" Q6P2H3 1 26234200-26278808 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 132.9;tongue: 65.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.0;Oligodendrocytes: 28.8;Spermatocytes: 40.9;Spermatogonia: 34.2;Syncytiotrophoblasts: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 19.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028252 Approved Approved "Nucleoli,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli, Golgi apparatus" "Centrosome, Cytosol" "HPA028252: AB_1846142" "unprognostic (1.08e-1)" "unprognostic (2.59e-2)" "unprognostic (1.74e-2)" "unprognostic (4.16e-2)" "unprognostic (2.66e-1)" "unprognostic (5.30e-3)" "prognostic unfavorable (4.39e-6)" "unprognostic (3.72e-2)" "unprognostic (5.30e-2)" "unprognostic (8.24e-2)" "unprognostic (9.18e-2)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (7.33e-3)" "unprognostic (5.41e-2)" "unprognostic (1.02e-2)" "unprognostic (2.60e-2)" 2.8 3.5 3.9 5.3 8.3 20.8 3.8 5.6 6.7 4.1 3.7 5.4 3.4 3.2 3.2 8.6 2.7 2.7 25.5 4.3 5.9 6.0 5.8 4.7 6.9 7.1 6.8 3.3 5.0 8.8 6.1 3.2 8.9 2.9 6.0 14.1 5.3 2.4 132.9 9.8 5.2 3.7 3.7 6.3 4.7 31.1 7.1 13.6 7.8 65.9 7.8 3.2 6.2 14.3 29.6 12.5 30.2 22.6 7.3 8.9 52.5 18.8 11.5 31.9 28.5 17.4 28.2 34.3 20.1 9.2 14.6 25.5 41.0 14.4 29.9 23.5 20.9 49.7 31.9 19.4 6.6 46.2 43.8 3.8 13.7 24.9 16.4 12.8 14.5 47.7 57.4 39.9 19.2 9.8 38.7 35.2 23.0 17.4 20.8 39.8 31.3 29.7 10.4 5.5 41.4 16.7 24.5 19.8 15.7 21.5 14.5 26.4 14.3 17.1 26.7 19.3 24.7 30.0 48.4 38.9 9.8 65.2 27.5 5.0 6.4 19.2 3.5 6.1 2.8 2.6 2.6 2.7 4.9 1.8 2.2 3.5 0.6 2.3 7.4 2.1 3.6 3.6 3.9 8.3 5.6 6.7 4.3 5.9 7.1 6.8 8.9 3.7 7.1 14.3 1.0 0.0 2.2 3.6 2.7 6.9 4.0 2.5 6.2 11.2 3.7 2.9 29.0 1.5 3.7 5.5 12.5 3.4 5.1 6.9 7.9 1.7 1.0 3.4 2.3 2.0 1.8 16.8 12.8 1.3 3.9 2.3 3.6 4.9 2.5 9.1 1.4 3.1 4.8 0.0 9.9 3.7 2.0 5.0 3.7 2.9 1.5 4.3 1.8 4.7 4.0 1.8 2.1 3.0 28.8 2.7 3.4 0.4 4.4 2.5 2.3 1.1 2.0 11.1 0.0 2.4 2.3 40.9 34.2 8.6 6.1 41.7 3.4 2.3 4.5 4.5 CFAP61 "C20orf26, CaM-IP3, dJ1002M8.3, DKFZP434K156" ENSG00000089101 "Cilia and flagella associated protein 61" Q8NHU2 20 20052514-20360703 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 16.1;skeletal muscle: 28.6;testis: 15.5" "Cell type enhanced" "Detected in some" "Early spermatids: 88.7;Excitatory neurons: 20.6;Late spermatids: 73.2;Spermatocytes: 17.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 4.7;HMC-1: 2.6;SCLC-21H: 5.1;SK-MEL-30: 2.2;U-87 MG: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009079 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA009079: AB_1078344" "unprognostic (5.93e-2)" "unprognostic (1.27e-1)" "unprognostic (6.73e-2)" "unprognostic (1.38e-3)" "unprognostic (6.20e-3)" "unprognostic (3.67e-3)" "unprognostic (8.58e-4)" "unprognostic (8.24e-2)" "unprognostic (8.29e-2)" "unprognostic (3.11e-1)" "unprognostic (1.86e-2)" "unprognostic (1.56e-1)" "unprognostic (2.76e-4)" "unprognostic (2.77e-1)" "unprognostic (9.27e-2)" "unprognostic (3.10e-3)" "unprognostic (3.06e-1)" 0.1 0.7 1.4 0.0 2.2 0.0 0.2 0.9 1.2 0.6 16.1 0.1 0.0 0.7 0.9 0.1 12.2 0.1 12.4 2.2 3.2 0.7 0.0 1.3 0.1 5.3 7.3 0.3 0.3 0.5 3.6 0.0 3.9 0.3 0.0 1.8 0.2 0.2 28.6 0.5 0.0 0.1 4.3 0.0 0.1 15.5 3.7 0.1 0.7 10.2 0.1 0.0 0.1 2.6 0.2 0.5 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.4 4.7 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.5 0.7 0.0 0.3 0.0 0.0 0.0 2.6 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.8 0.4 0.0 5.1 0.0 0.1 0.3 2.2 0.0 0.4 0.0 0.4 0.0 0.2 0.3 0.2 0.7 0.3 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.4 2.2 0.9 1.2 2.2 3.2 5.3 7.3 3.9 4.3 3.7 2.6 0.0 0.0 0.5 2.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.1 12.7 0.0 2.5 1.8 4.2 0.0 1.4 0.0 0.0 0.0 88.7 12.1 0.3 0.1 0.0 0.0 20.6 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 12.6 0.0 0.0 0.0 0.0 73.2 0.6 0.2 0.0 1.0 0.0 0.0 0.0 3.5 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 8.7 0.5 0.0 0.6 0.1 17.3 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 CFAP77 "C9orf171, FLJ46082" ENSG00000188523 "Cilia and flagella associated protein 77" Q6ZQR2 9 132410043-132573319 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 11.5;fallopian tube: 29.7;testis: 19.3" "Cell type enhanced" "Detected in some" "Early spermatids: 127.1;Endometrial ciliated cells: 58.4;Late spermatids: 47.6;Respiratory ciliated cells: 36.5;Spermatocytes: 25.5" "Cancer enhanced" "Detected in some" "endometrial cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SH-SY5Y: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021329, HPA024647, HPA061069" Enhanced Approved Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA021329: AB_1848950, HPA024647: AB_10601126, HPA061069: AB_2732657" "unprognostic (7.28e-4)" "unprognostic (5.68e-2)" "unprognostic (5.25e-2)" "prognostic favorable (7.31e-4)" "unprognostic (1.70e-2)" "unprognostic (1.74e-1)" "unprognostic (3.01e-1)" "unprognostic (2.31e-2)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (1.77e-1)" "unprognostic (2.41e-3)" "unprognostic (2.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" 0.0 0.0 1.2 0.0 1.0 0.0 0.0 2.0 0.1 1.2 11.5 0.0 0.0 0.5 0.2 0.0 29.7 0.0 2.4 1.0 1.5 0.1 0.0 2.1 0.0 4.1 6.0 0.0 0.1 0.0 0.6 0.0 3.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 19.3 1.4 0.2 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.0 2.0 0.1 1.0 1.5 4.1 6.0 3.1 3.3 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 127.1 58.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.6 0.3 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 36.5 3.8 0.0 0.0 0.0 25.5 3.5 0.0 0.0 0.1 0.1 0.1 0.0 0.1 CFAP94 "CASC1, FLJ10921, LAS1, PPP1R54" ENSG00000118307 "Cilia and flagella associated protein 94" Q6TDU7 12 25108289-25195162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.4;fallopian tube: 14.0;testis: 22.9" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 1.9;Fibroblasts: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "T-47d: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039662, HPA040141" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Cytosol Vesicles "HPA039662: AB_10795468, HPA040141: " "unprognostic (6.42e-3)" "unprognostic (1.26e-2)" "unprognostic (1.95e-2)" "unprognostic (2.04e-3)" "unprognostic (4.62e-1)" "unprognostic (1.85e-2)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (2.22e-1)" "unprognostic (3.91e-2)" "unprognostic (6.21e-4)" "unprognostic (2.54e-2)" "prognostic favorable (3.13e-4)" "unprognostic (2.01e-1)" "unprognostic (8.74e-3)" "unprognostic (7.16e-2)" "unprognostic (1.19e-1)" 0.2 0.7 1.6 0.2 2.3 0.6 1.5 0.9 2.0 2.0 12.4 0.3 0.0 1.6 6.0 0.5 14.0 0.7 0.4 2.1 2.3 2.7 0.0 1.9 0.4 5.7 6.0 1.2 0.7 3.3 4.0 0.1 4.2 1.0 0.0 5.1 0.7 1.1 0.1 1.0 0.1 0.3 4.0 0.2 0.6 22.9 3.0 0.4 4.1 0.0 0.1 0.2 0.2 2.5 0.1 0.3 0.4 0.3 0.2 0.2 0.2 0.0 0.3 0.2 0.3 0.0 1.0 1.1 0.3 0.0 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.2 0.0 0.4 0.0 1.1 0.6 0.4 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.4 0.1 0.0 1.0 0.1 0.6 0.2 0.1 0.0 0.1 0.5 1.3 0.0 0.0 0.1 0.8 0.5 0.1 0.4 0.2 0.9 0.3 0.2 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.6 0.0 0.2 0.0 0.9 0.1 0.2 1.3 0.3 0.2 0.3 0.0 0.1 1.6 2.3 0.9 2.0 2.1 2.3 5.7 6.0 4.2 4.0 3.0 2.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CHCHD7 "COX23, MGC2217" ENSG00000170791 "Coiled-coil-helix-coiled-coil-helix domain containing 7" Q9BUK0 8 56211686-56218809 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050783 Approved Approved "Cell Junctions,Aggresome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Cell Junctions" Aggresome "HPA050783: AB_2681236" "unprognostic (1.64e-2)" "unprognostic (3.23e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.46e-2)" "unprognostic (2.43e-1)" "unprognostic (5.04e-2)" "unprognostic (8.38e-3)" "unprognostic (1.62e-1)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "prognostic favorable (9.47e-5)" "unprognostic (1.94e-1)" "unprognostic (5.07e-1)" "unprognostic (1.77e-2)" "unprognostic (2.50e-1)" 24.9 20.2 25.8 30.0 27.1 29.2 25.8 30.8 32.5 22.9 25.2 30.7 33.2 18.6 46.0 22.8 24.5 17.1 41.6 26.6 26.6 42.2 26.2 28.0 39.4 27.0 26.3 49.1 26.9 36.0 38.1 19.3 27.3 26.4 30.2 32.6 35.3 21.0 37.5 21.3 36.0 18.5 28.6 46.3 27.7 11.7 26.7 36.5 28.0 39.7 38.1 28.1 24.2 28.7 59.3 18.9 39.4 13.1 100.9 71.3 42.4 41.0 37.0 30.7 23.0 46.2 68.9 54.7 34.8 23.6 43.6 32.3 40.7 61.3 38.6 24.5 77.4 83.6 45.5 66.2 51.8 72.1 52.0 86.2 54.2 22.2 98.0 43.8 32.8 100.0 41.8 34.9 74.1 29.0 72.2 106.5 35.1 93.5 25.6 82.0 12.0 46.3 57.3 63.3 10.2 7.0 21.8 32.2 31.2 47.8 34.1 40.5 49.0 16.5 35.4 53.7 39.5 37.1 40.3 93.5 46.0 105.3 28.9 55.2 37.8 53.3 42.4 38.2 40.2 60.4 46.9 43.5 44.1 52.5 55.0 49.6 15.2 49.7 35.0 62.6 60.1 33.9 25.8 27.1 30.8 32.5 26.6 26.6 27.0 26.3 27.3 28.6 26.7 28.7 31.7 19.2 77.9 2.6 72.5 20.8 44.1 49.0 16.5 31.4 37.1 27.1 93.7 35.8 48.0 49.7 14.6 44.0 66.0 75.4 125.2 41.4 27.5 25.2 15.9 29.8 39.6 32.6 9.1 75.4 80.8 26.3 92.8 32.2 53.8 13.8 42.8 78.4 162.3 13.5 8.0 66.3 34.6 67.8 45.3 13.4 37.0 58.0 53.4 14.0 68.5 50.8 60.8 1.5 6.5 65.4 63.9 30.9 59.3 45.3 115.0 82.3 41.5 37.9 13.1 23.9 39.0 51.4 39.4 34.7 23.9 42.1 61.7 21.7 73.5 48.8 CHRM2 ENSG00000181072 "Cholinergic receptor muscarinic 2" P08172 7 136868652-137020255 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 36.1;intestine: 21.2" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 59.9;Excitatory neurons: 49.4;Inhibitory neurons: 119.2" "Cancer enhanced" "Detected in single" "stomach cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 86.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022338, HPA029795" Approved NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022338: , HPA029795: AB_10601357" "unprognostic (3.51e-2)" "unprognostic (3.73e-4)" "unprognostic (5.77e-2)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.00e-1)" "unprognostic (2.69e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-3)" 0.1 0.2 2.8 1.3 2.0 0.1 0.0 0.1 2.3 0.3 0.0 21.2 0.7 0.4 0.0 0.3 0.3 10.7 36.1 0.1 2.5 0.0 1.1 0.8 0.0 9.3 5.4 0.2 0.1 0.0 0.0 1.4 9.1 0.2 3.5 0.8 0.0 0.0 0.0 0.1 4.4 9.7 1.8 0.0 5.9 0.6 6.8 0.1 0.0 0.0 0.0 8.9 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 17.6 0.2 0.0 0.0 0.0 0.0 0.0 86.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.0 0.1 2.3 0.1 2.5 9.3 5.4 9.1 1.8 6.8 1.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 59.9 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.2 0.2 0.0 0.0 49.4 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 119.2 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.8" "Cell type enhanced" "Detected in many" "Club cells: 115.2;Muller glia cells: 69.2;Oligodendrocyte precursor cells: 167.4;Respiratory ciliated cells: 311.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.3;Hep G2: 13.8;RPTEC TERT1: 41.8;SCLC-21H: 9.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" 0.0 0.2 0.8 0.1 0.9 0.0 2.9 0.7 2.4 2.8 0.0 1.6 0.2 0.1 0.4 1.6 10.3 3.1 2.6 2.7 1.2 1.6 8.2 4.3 0.0 3.5 2.3 0.0 9.3 0.0 1.9 0.0 1.2 3.5 0.2 7.3 13.8 1.8 0.2 0.1 0.3 0.1 2.0 5.7 0.7 6.9 1.2 1.0 0.0 0.9 0.6 1.5 0.7 1.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 41.8 0.0 9.0 0.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.7 2.4 2.7 1.2 3.5 2.3 1.2 2.0 1.2 1.9 0.1 0.0 2.7 24.8 0.0 0.6 32.6 56.6 4.6 1.3 8.2 8.0 9.2 35.8 115.2 5.5 0.0 0.4 0.1 0.0 11.7 13.0 7.1 49.9 0.7 0.3 3.5 0.0 10.1 0.6 0.1 4.2 0.0 1.8 5.1 0.1 0.0 10.7 0.3 0.0 29.3 0.1 22.4 0.0 0.0 4.4 0.6 0.5 7.2 1.0 0.0 69.2 0.0 167.4 1.0 1.3 0.0 0.4 0.0 8.9 0.0 0.3 311.6 3.2 0.0 3.2 3.7 0.9 1.3 4.7 0.0 0.3 0.4 0.0 0.0 40.3 CITED4 ENSG00000179862 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4" Q96RK1 1 40861054-40862363 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 172.1;Breast glandular cells: 183.7;Breast myoepithelial cells: 225.0;Cholangiocytes: 258.7;Endometrial ciliated cells: 350.4;Glandular and luminal cells: 202.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 91.3;THP-1: 264.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056434 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA056434: AB_2683132" "unprognostic (5.39e-3)" "unprognostic (5.41e-2)" "unprognostic (1.53e-1)" "prognostic favorable (4.38e-5)" "unprognostic (3.43e-3)" "unprognostic (1.90e-2)" "unprognostic (3.44e-3)" "unprognostic (3.42e-2)" "unprognostic (2.67e-1)" "unprognostic (1.98e-3)" "unprognostic (2.25e-2)" "unprognostic (6.00e-2)" "unprognostic (2.29e-3)" "unprognostic (2.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.11e-1)" "unprognostic (6.13e-2)" 13.7 15.1 9.3 1.1 10.6 19.1 30.3 9.4 9.5 18.0 4.3 28.9 1.6 17.1 2.4 29.0 14.4 1.9 26.6 6.6 14.5 20.4 38.8 11.4 1.7 14.6 15.4 10.3 49.1 4.4 4.9 1.7 10.6 16.4 0.4 0.8 34.2 8.5 33.0 51.5 7.7 2.3 12.0 29.9 13.4 25.4 13.1 1.2 7.3 9.2 1.3 8.9 23.7 10.5 29.5 5.7 1.6 34.6 0.7 1.3 34.4 1.9 2.1 0.7 0.8 3.0 38.5 0.1 4.6 0.5 1.0 44.6 2.4 24.0 0.6 0.1 0.4 0.2 3.3 4.9 5.9 1.0 0.4 4.2 10.1 2.3 7.6 2.8 1.8 0.4 0.1 0.1 1.3 0.9 0.5 19.6 11.1 0.9 3.9 0.3 0.0 0.1 91.3 16.9 6.7 1.9 1.4 35.8 2.0 3.7 17.4 264.9 2.3 0.0 0.0 0.4 1.1 0.0 0.8 0.0 0.0 13.8 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 9.3 10.6 9.4 9.5 6.6 14.5 14.6 15.4 10.6 12.0 13.1 10.5 17.4 9.6 1.1 1.3 4.0 19.1 172.1 2.1 37.0 4.0 183.7 225.0 10.4 258.7 3.5 22.0 0.0 1.0 11.9 3.7 43.0 14.2 47.9 350.4 24.4 48.9 7.7 9.7 2.0 43.6 0.9 14.0 17.9 202.6 0.0 30.5 11.4 43.1 1.3 1.7 1.7 4.8 2.0 10.4 3.2 64.8 5.0 13.7 19.6 1.0 4.6 46.1 2.1 2.0 3.8 33.0 3.4 5.7 2.4 65.6 0.2 88.0 6.5 3.0 19.7 72.2 19.7 0.9 1.5 49.9 24.3 0.1 14.6 37.3 3.6 122.3 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 694.7;intestine: 653.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 2767.4;Distal enterocytes: 4691.8;Distal tubular cells: 2281.3;Horizontal cells: 5042.4;Muller glia cells: 3639.8;Rod photoreceptor cells: 3789.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 290.8" "Lineage enriched" "Detected in many" 18 "monocytes: 290.8" "Cell line enhanced" "Detected in many" "CACO-2: 455.8;HEK 293: 1399.8;SCLC-21H: 792.2;SH-SY5Y: 352.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favorable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 90.7 60.0 471.6 25.8 627.0 3.2 47.2 641.1 694.7 105.2 192.7 653.4 36.0 222.6 16.0 54.5 197.9 17.9 269.8 428.7 482.3 161.0 9.0 60.3 4.0 427.5 440.4 58.8 27.7 108.2 74.0 4.7 345.1 301.8 151.9 471.3 37.9 208.3 80.0 76.5 120.8 113.8 434.5 6.8 479.9 97.6 596.2 2.8 87.9 47.1 5.1 298.4 101.6 383.6 2.4 54.5 321.1 14.7 4.4 2.3 6.3 37.5 0.3 2.4 1.4 455.8 7.3 0.4 36.9 29.1 9.9 70.2 109.9 1.5 0.2 9.6 1399.8 111.0 242.1 165.4 16.6 0.7 87.9 14.7 0.6 3.9 0.8 3.3 0.0 5.1 198.7 3.7 4.8 20.0 2.3 3.9 109.1 48.3 213.6 13.9 6.8 275.9 65.9 2.5 792.2 352.2 65.3 10.6 25.2 21.6 21.1 40.9 2.2 1.5 56.3 4.7 147.3 21.1 2.7 7.2 6.4 2.1 14.1 2.4 0.5 14.6 0.3 28.5 0.4 0.0 0.2 0.1 16.4 0.2 0.1 0.5 1.0 0.2 290.8 0.0 0.7 6.0 471.6 627.0 641.1 694.7 428.7 482.3 427.5 440.4 345.1 434.5 596.2 383.6 14.8 195.5 103.5 515.8 13.5 153.7 296.2 257.6 56.3 2767.4 41.5 48.9 553.5 145.8 117.9 114.0 1909.9 4.4 3.4 4691.8 2281.3 127.6 445.8 773.2 205.7 60.8 467.1 9.9 178.0 42.5 11.7 96.6 359.4 408.5 28.6 476.1 74.6 9.2 8.2 5042.4 147.0 726.0 187.2 2.8 44.9 147.4 304.1 39.8 181.5 88.1 74.2 3639.8 0.0 93.5 161.2 131.4 1996.9 1089.3 6.6 279.8 9.5 118.0 456.1 3789.9 59.2 15.4 222.6 127.3 97.4 22.1 175.2 41.6 19.1 12.2 755.6 220.1 CLCNKB hClC-Kb ENSG00000184908 "Chloride voltage-gated channel Kb" P51801 1 16043736-16057308 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 209.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Distal tubular cells: 58.7;Early spermatids: 24.6;Ionocytes: 116.0;Late spermatids: 104.2" "Cancer enriched" "Detected in some" 9 "renal cancer: 24.9" "Region enriched" "Detected in some" 6 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.6;HeLa: 1.1" HPA057717 Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "HPA057717: AB_2683509" "unprognostic (9.05e-4)" "unprognostic (1.72e-1)" "unprognostic (2.41e-2)" "unprognostic (2.68e-3)" "unprognostic (1.44e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-4)" "unprognostic (1.87e-1)" "unprognostic (3.61e-2)" "unprognostic (2.31e-1)" "unprognostic (4.57e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.27e-7)" "unprognostic (2.04e-2)" "unprognostic (4.62e-1)" "unprognostic (1.78e-2)" "unprognostic (5.14e-2)" 0.6 1.7 0.1 0.0 0.3 0.0 0.3 7.0 0.3 0.7 0.6 0.4 0.0 0.9 0.7 0.2 0.4 0.2 4.0 0.1 0.3 209.7 0.0 0.4 0.0 0.4 0.5 1.3 1.1 4.9 2.5 0.3 1.2 0.7 0.3 1.2 48.1 1.5 0.1 0.1 0.1 0.3 0.3 0.1 0.7 2.8 0.5 0.1 16.1 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.7 0.0 1.6 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 7.0 0.3 0.1 0.3 0.4 0.5 1.2 0.3 0.5 0.6 0.0 3.2 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.1 0.3 4.2 0.0 1.4 23.9 0.0 0.3 0.0 0.6 58.7 1.0 24.6 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.3 116.0 0.0 0.0 104.2 0.9 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 1.6 0.9 0.0 0.0 0.5 0.1 0.0 0.9 0.1 CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.3;Early spermatids: 162.4;Endometrial ciliated cells: 93.4;Muller glia cells: 176.4;Spermatocytes: 465.5" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 53.0;MOLT-4: 47.8;U-251 MG: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" 0.4 6.6 0.9 1.0 0.7 2.4 2.7 3.8 1.6 0.9 2.0 2.6 0.5 1.6 0.6 1.2 13.7 0.4 59.5 0.9 2.6 0.4 3.2 0.5 0.7 2.7 1.9 0.3 2.2 0.6 11.2 0.2 2.6 22.5 1.3 17.2 1.0 0.7 0.4 0.2 1.3 1.5 1.2 0.2 2.0 113.6 2.3 2.4 2.7 1.6 1.2 0.6 0.1 0.9 0.2 10.2 10.3 6.9 4.0 21.1 2.4 0.1 9.4 10.0 18.6 0.3 0.9 0.0 27.8 0.9 8.4 0.2 7.5 0.1 16.2 0.4 9.0 3.0 9.8 7.4 41.4 38.9 0.6 2.2 39.2 1.0 0.9 53.0 0.2 9.6 2.0 0.0 0.0 0.5 47.8 0.5 12.0 0.2 28.1 31.5 0.0 0.4 0.0 0.3 16.8 29.8 6.5 4.1 1.8 3.8 1.9 5.6 0.0 27.4 4.7 9.7 73.6 14.4 31.7 19.9 43.4 1.6 2.9 0.9 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 3.8 1.6 0.9 2.6 2.7 1.9 2.6 1.2 2.3 0.9 0.8 0.0 2.2 0.3 0.1 0.0 0.9 8.5 1.2 9.2 3.3 1.8 313.3 0.0 6.4 0.0 4.2 0.5 0.0 0.5 0.0 1.2 162.4 93.4 1.3 11.9 5.3 8.6 7.2 4.2 0.1 10.2 0.0 11.3 0.0 10.1 0.7 3.7 0.1 25.2 6.7 0.4 30.5 0.0 0.0 60.2 5.0 0.7 1.8 0.0 0.1 176.4 0.0 6.6 0.6 0.9 3.9 4.5 0.1 33.8 0.2 0.1 24.6 16.3 0.0 0.6 2.0 465.5 23.9 2.8 0.1 0.3 0.7 0.2 0.8 1.3 CLIC6 "CLIC1L, CLIC5" ENSG00000159212 "Chloride intracellular channel 6" Q96NY7 21 34668994-34718227 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 235.9;stomach 1: 138.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Club cells: 41.6;Gastric mucus-secreting cells: 26.5;Respiratory ciliated cells: 81.1;Skeletal myocytes: 24.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.6;NTERA-2: 3.6;T-47d: 7.3;THP-1: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065285 Enhanced NA NA 180000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA065285: AB_2685454" "prognostic favorable (6.11e-5)" "unprognostic (2.17e-2)" "unprognostic (1.65e-2)" "unprognostic (4.27e-2)" "unprognostic (2.93e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-2)" "prognostic favorable (3.15e-5)" "unprognostic (4.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (1.99e-1)" "unprognostic (1.43e-3)" 11.4 0.1 1.2 4.3 0.7 0.1 11.9 2.4 1.0 15.8 235.9 4.0 2.0 2.1 2.7 2.6 11.4 8.8 11.1 11.3 0.7 2.6 0.9 9.8 1.2 3.0 4.5 4.9 3.2 28.3 3.3 0.1 2.6 9.8 2.9 0.2 25.4 7.0 1.6 6.0 3.1 0.7 1.3 1.0 138.5 0.3 4.4 8.4 13.2 4.3 3.8 12.9 5.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.9 7.3 3.4 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 2.4 1.0 11.3 0.7 3.0 4.5 2.6 1.3 4.4 0.7 0.3 6.4 20.7 1.3 0.0 0.6 5.1 7.3 4.0 0.0 15.6 11.0 11.4 30.0 41.6 9.2 0.0 0.0 0.2 2.2 1.9 8.0 0.1 15.1 0.3 0.4 4.9 0.0 0.3 0.9 0.0 3.7 26.5 2.2 1.3 11.8 0.0 0.0 0.1 0.0 0.6 1.4 16.2 0.0 0.4 0.3 0.3 0.4 7.2 0.0 0.6 0.0 0.0 0.0 0.1 17.2 0.6 3.0 0.4 10.2 0.1 0.2 81.1 0.0 0.0 24.0 2.4 0.2 0.2 0.6 0.4 0.0 0.4 0.0 2.8 20.4 CLTRN "NX17, TMEM27" ENSG00000147003 "Collectrin, amino acid transport regulator" Q9HBJ8 X 15627318-15675012 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 486.4" "Cell type enriched" "Detected in some" 16 "Proximal tubular cells: 885.4" "Cancer enriched" "Detected in many" 35 "renal cancer: 106.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;hTERT-HME1: 5.2;RPTEC TERT1: 8.5;SuSa: 5.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA048543 Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum, Vesicles" "HPA048543: AB_2680436" "unprognostic (1.27e-1)" "unprognostic (4.77e-2)" "unprognostic (2.45e-2)" "unprognostic (2.66e-2)" "unprognostic (5.20e-2)" "unprognostic (5.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-2)" "prognostic favorable (5.65e-4)" "unprognostic (1.05e-2)" "unprognostic (3.03e-1)" "prognostic favorable (6.78e-9)" "unprognostic (1.77e-1)" "unprognostic (2.60e-2)" "unprognostic (2.58e-1)" "unprognostic (1.33e-2)" 0.5 0.8 0.5 0.0 0.6 0.3 2.0 0.7 0.8 1.0 16.6 0.6 1.3 1.5 3.1 0.6 2.4 3.7 1.1 0.7 0.6 486.4 61.5 1.7 0.4 0.6 0.5 3.2 5.3 10.5 0.6 0.5 0.6 1.5 0.3 1.2 0.8 1.3 0.1 1.2 0.4 0.4 0.4 0.2 10.9 1.0 0.5 0.8 4.1 0.1 0.3 0.8 0.4 0.9 2.3 1.8 1.1 0.3 0.7 1.0 0.7 0.0 0.0 0.1 0.1 0.1 0.5 0.1 1.6 0.2 0.2 8.5 0.7 2.3 0.0 0.3 0.7 0.2 0.0 0.8 1.0 0.0 0.0 0.2 2.0 0.3 5.2 0.6 0.0 2.1 0.5 0.4 0.2 2.8 0.1 0.3 2.9 0.8 2.6 0.2 0.3 0.9 8.5 0.1 1.1 1.0 0.6 0.1 1.8 5.1 0.6 0.2 0.0 0.2 0.4 0.3 0.0 0.4 0.2 0.3 0.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.2 0.1 0.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.7 0.8 0.7 0.6 0.6 0.5 0.6 0.4 0.5 0.9 0.1 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 0.0 3.0 3.2 0.0 0.0 1.8 27.6 0.0 2.1 0.0 0.0 54.8 25.1 0.0 2.8 0.6 0.1 0.0 0.0 0.0 0.6 0.5 0.3 0.0 3.3 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 885.4 2.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 3.7 0.5 0.0 0.0 CLUH "CLU1, KIAA0664" ENSG00000132361 "Clustered mitochondria homolog" O75153 17 2689386-2712663 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CACO-2: 266.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031505, HPA044346" Uncertain Supported "Nuclear bodies,Vesicles" NA NA 5500 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Nuclear bodies" "HPA031505: AB_2673912, HPA044346: AB_10962153" "unprognostic (3.48e-2)" "unprognostic (3.97e-2)" "unprognostic (9.02e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (2.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.84e-1)" "unprognostic (2.69e-2)" "unprognostic (5.64e-2)" "unprognostic (5.11e-2)" "prognostic favorable (1.92e-5)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-2)" "unprognostic (6.26e-2)" 30.8 56.7 13.8 18.1 12.7 14.3 28.5 16.3 18.3 19.8 19.7 45.9 46.6 21.3 1.9 67.7 19.2 15.4 80.8 14.5 11.2 50.6 135.0 19.6 14.6 14.6 13.2 17.0 50.4 15.6 20.3 9.0 15.3 24.7 13.2 7.2 32.1 11.8 127.8 47.5 34.2 8.5 9.3 25.2 35.1 25.2 17.3 6.4 25.2 52.9 11.1 29.6 29.2 11.2 69.5 131.9 8.9 33.3 20.2 14.1 99.9 34.9 13.0 41.9 31.0 266.2 30.0 122.6 41.5 19.4 26.9 127.6 45.3 52.9 14.7 43.6 86.4 68.0 112.2 93.9 17.1 53.7 44.1 22.6 29.7 48.9 24.7 9.4 20.5 43.3 81.8 42.2 11.7 79.8 69.6 58.0 28.2 35.8 67.8 104.7 37.0 70.8 26.0 117.3 43.9 32.6 40.0 129.4 44.4 6.6 72.7 31.3 33.7 33.7 44.9 92.2 80.5 18.2 22.9 49.7 35.4 73.2 41.6 0.0 2.2 0.0 1.7 3.1 1.3 2.2 1.0 0.9 2.4 2.2 2.3 2.1 0.2 0.6 2.0 2.7 1.5 0.9 13.8 12.7 16.3 18.3 14.5 11.2 14.6 13.2 15.3 9.3 17.3 11.2 5.8 6.4 20.9 20.9 6.5 30.5 12.0 11.7 16.5 18.5 23.5 22.7 42.1 41.5 16.7 18.4 22.9 9.7 7.6 47.8 11.7 18.4 1.8 12.7 10.8 8.5 25.8 22.1 9.9 18.3 8.2 6.8 22.4 24.6 1.3 18.1 6.8 122.1 13.1 8.4 11.4 38.8 14.2 10.3 6.3 4.0 5.0 7.9 21.4 4.7 7.4 6.5 2.1 7.5 6.2 19.6 21.2 6.0 11.7 22.9 39.2 35.1 14.1 17.1 6.6 12.3 11.3 8.6 17.5 42.4 35.5 8.2 7.2 43.3 68.3 22.5 CLYBL CLB ENSG00000125246 "Citramalyl-CoA lyase" Q8N0X4 13 99606669-99897134 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.7" "Cell type enhanced" "Detected in many" "Astrocytes: 84.9;Distal tubular cells: 138.9;Hepatocytes: 84.1;Proximal tubular cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 56.1;SCLC-21H: 53.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039959, HPA040691" Enhanced NA NA 7300 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039959: AB_10793857, HPA040691: AB_10794746" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.30e-3)" "unprognostic (7.57e-3)" "unprognostic (3.69e-1)" "unprognostic (2.90e-2)" "unprognostic (1.57e-3)" "unprognostic (2.91e-1)" "unprognostic (2.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.49e-2)" "unprognostic (2.85e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.74e-2)" "unprognostic (5.41e-2)" "unprognostic (4.78e-2)" "unprognostic (7.82e-2)" 7.1 16.2 11.4 5.5 11.8 5.1 10.5 24.4 12.7 7.7 35.3 20.6 25.0 6.5 13.0 11.3 7.9 6.9 22.6 12.6 8.6 66.0 109.7 5.6 10.4 9.1 9.0 5.7 9.8 14.4 6.7 3.7 7.3 6.9 21.9 7.3 12.3 8.9 43.3 9.3 23.5 6.4 5.6 8.6 8.7 9.3 10.7 5.8 12.3 69.5 10.8 7.4 6.9 8.8 0.4 2.3 16.6 7.5 7.6 7.0 3.6 0.8 1.6 1.4 2.6 0.3 12.4 3.0 4.8 1.0 3.2 3.9 1.5 2.8 1.8 15.3 2.4 19.2 4.9 11.8 5.2 10.4 1.3 3.8 8.3 0.2 6.4 1.6 2.2 15.7 2.7 9.8 1.6 4.3 4.7 14.3 10.8 56.1 3.4 6.0 0.7 7.1 16.6 1.1 53.1 8.1 3.4 3.8 3.6 5.9 8.0 13.2 0.3 0.7 1.9 1.4 2.7 22.3 4.7 0.6 11.3 14.9 2.3 1.7 4.5 0.5 9.9 10.0 12.0 14.5 17.4 13.9 9.4 15.7 13.3 15.8 0.6 14.2 4.8 10.3 24.2 7.7 11.4 11.8 24.4 12.7 12.6 8.6 9.1 9.0 7.3 5.6 10.7 8.8 7.4 6.4 5.0 84.9 8.6 5.5 9.1 18.4 8.6 2.3 8.9 11.3 36.1 21.5 10.9 14.7 2.1 14.3 9.2 17.9 138.9 11.6 1.6 6.1 4.1 6.2 1.2 2.5 30.6 8.1 3.2 5.9 5.6 4.4 6.3 7.1 4.6 84.1 7.6 0.0 25.6 11.5 10.2 6.7 4.5 4.8 2.1 5.4 16.0 48.7 4.4 6.5 7.2 21.6 9.5 4.0 13.8 4.1 3.8 4.3 23.1 144.7 4.1 5.0 0.0 7.6 18.1 3.0 10.5 6.9 6.3 7.4 8.3 13.6 19.1 6.7 CMBL FLJ23617 ENSG00000164237 "Carboxymethylenebutenolidase homolog" Q96DG6 5 10275875-10307902 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 172.4;skeletal muscle: 164.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 185.2;Distal tubular cells: 215.2;Proximal enterocytes: 716.0;Proximal tubular cells: 465.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 48.5;K-562: 51.4;PC-3: 46.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036571 Uncertain NA NA 580000 "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036571: AB_10670114" "unprognostic (1.81e-2)" "unprognostic (2.55e-1)" "unprognostic (8.10e-3)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.20e-1)" "unprognostic (8.64e-2)" "prognostic favorable (1.99e-4)" "unprognostic (1.76e-1)" "unprognostic (4.44e-2)" "unprognostic (1.29e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (2.44e-1)" 11.3 31.5 8.9 3.8 8.7 4.0 10.6 7.2 10.2 7.2 8.1 53.6 95.8 8.5 9.9 3.8 13.5 14.2 22.9 8.5 8.5 168.5 172.4 6.8 1.2 8.5 8.9 23.3 16.6 26.6 10.6 2.1 9.0 14.3 34.7 1.3 9.6 7.4 164.4 2.8 85.0 6.4 8.0 2.7 28.5 3.2 10.0 2.9 9.8 42.4 0.5 9.7 6.4 7.7 5.9 7.2 8.2 20.3 32.0 35.7 41.2 9.7 11.1 3.0 4.5 3.0 30.9 0.1 15.4 7.8 14.5 0.1 19.7 12.8 4.1 0.3 13.4 27.4 28.6 24.3 9.8 0.2 0.2 48.5 8.5 6.7 6.1 11.7 9.4 0.0 51.4 0.4 11.6 1.3 0.1 1.1 12.1 0.0 46.0 5.9 0.0 0.6 32.2 3.8 6.3 9.7 23.1 2.2 0.7 9.7 16.7 1.0 2.7 4.6 6.0 7.6 0.1 0.2 0.1 0.1 8.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 8.9 8.7 7.2 10.2 8.5 8.5 8.5 8.9 9.0 8.0 10.0 7.7 4.0 25.6 17.2 2.9 2.2 3.7 17.8 6.3 14.8 2.0 40.1 16.8 86.0 55.8 14.8 23.9 4.2 15.3 0.9 185.2 215.2 10.7 3.2 26.5 25.8 7.1 19.2 56.1 5.0 15.6 10.6 37.1 133.0 19.2 13.3 47.4 14.3 161.2 12.1 0.0 6.9 100.5 2.0 4.1 3.8 3.5 47.8 5.5 1.8 1.9 0.4 17.5 1.0 4.0 0.4 16.1 118.6 41.3 0.5 17.5 716.0 465.4 13.0 3.1 0.0 31.0 12.7 1.0 5.9 5.2 3.8 4.9 4.4 145.0 162.7 15.6 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.6;urinary bladder: 40.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 24.5;Basal respiratory cells: 16.0;Cardiomyocytes: 13.1;Prostatic glandular cells: 12.1;Urothelial cells: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.0;HeLa: 40.1;HHSteC: 59.2;hTERT-HME1: 44.1;HUVEC TERT2: 41.7;TIME: 94.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Endoplasmic reticulum" "HPA065393: AB_2685483" "unprognostic (8.47e-3)" "unprognostic (4.50e-3)" "unprognostic (9.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.72e-1)" "unprognostic (9.84e-2)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (8.54e-3)" "unprognostic (3.51e-1)" 3.0 0.5 0.3 0.4 0.3 0.0 2.0 0.2 0.2 12.6 1.3 1.9 1.4 32.6 17.0 5.5 14.9 13.3 5.4 0.3 0.7 4.2 0.1 1.0 0.1 0.9 1.7 9.3 0.1 5.5 7.2 3.2 1.0 12.5 2.1 1.2 1.4 21.5 1.4 6.5 1.5 24.5 0.4 1.4 13.3 1.2 0.3 0.9 0.7 1.2 0.1 40.7 9.2 0.6 0.1 31.1 9.9 0.0 24.2 1.7 0.0 0.0 1.8 0.3 0.2 17.9 0.0 0.0 0.0 0.0 3.9 5.8 10.3 46.0 0.8 0.4 8.8 0.8 40.1 0.3 59.2 0.0 0.0 2.6 27.8 6.5 44.1 0.1 41.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 14.0 0.0 3.8 0.0 0.0 0.0 1.9 3.4 0.0 0.0 2.4 0.0 0.0 18.2 0.9 0.0 94.2 0.0 0.1 5.5 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.2 0.3 0.7 0.9 1.7 1.0 0.4 0.3 0.6 0.1 0.0 0.0 6.2 0.0 6.4 24.5 16.0 3.4 0.2 2.3 6.1 13.1 0.0 2.6 1.8 0.0 0.1 0.0 0.0 1.9 0.0 2.1 0.7 6.0 0.4 0.0 0.0 0.4 0.0 0.0 6.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 2.0 0.0 0.3 0.3 4.1 0.0 0.0 8.4 0.0 5.5 0.0 0.0 0.6 0.1 0.0 9.1 0.0 12.1 0.0 0.0 2.2 0.4 0.0 0.4 7.2 0.2 0.2 0.1 3.7 0.0 0.1 0.8 0.0 15.2 COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 72.5;Basal respiratory cells: 59.3;Basal squamous epithelial cells: 67.2;Endometrial stromal cells: 45.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 65.7;HaCaT: 63.5;HBEC3-KT: 100.6;HDLM-2: 97.8;HeLa: 146.2;SiHa: 82.8" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" 0.8 1.1 1.4 3.8 1.0 0.1 4.9 2.8 2.1 24.3 0.4 2.9 1.7 12.1 6.7 21.8 6.4 4.0 3.2 0.3 6.5 7.4 1.3 1.7 1.2 7.0 3.2 3.4 0.4 0.0 2.5 1.6 3.0 34.2 0.9 1.4 11.5 12.2 3.5 98.2 4.1 2.5 2.6 6.5 2.1 3.6 6.5 1.2 0.5 0.6 1.3 6.6 29.2 0.6 0.2 25.4 1.2 0.5 9.2 12.3 31.0 65.7 40.8 16.9 10.0 0.4 0.5 0.1 2.0 15.0 15.4 63.5 0.0 100.6 3.1 97.8 0.5 0.2 146.2 4.3 25.6 0.0 0.4 19.9 58.8 34.4 26.8 23.1 0.0 0.7 0.5 0.7 2.0 0.3 0.0 0.9 3.1 1.3 1.3 0.5 2.2 0.2 9.2 0.2 0.2 0.2 82.8 0.1 0.8 3.7 1.3 0.3 0.0 5.6 3.2 3.2 50.1 1.8 1.8 0.1 49.0 0.4 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 2.8 2.1 0.3 6.5 7.0 3.2 3.0 2.6 6.5 0.6 0.4 0.0 0.0 10.7 0.2 72.5 24.1 59.3 67.2 17.7 1.0 10.2 6.6 0.0 10.6 11.0 10.4 1.4 0.1 0.6 0.0 0.9 11.8 3.1 45.3 1.4 1.8 0.0 6.8 0.7 1.0 8.3 1.1 4.0 0.0 0.8 0.4 0.7 1.6 8.4 11.6 0.7 0.0 0.3 4.2 6.3 5.0 0.8 8.8 8.4 0.1 2.6 0.0 4.0 4.4 15.6 0.1 5.7 0.0 5.7 0.2 0.3 2.5 12.9 0.0 2.0 13.4 2.6 1.5 11.3 24.2 1.2 0.8 5.0 0.2 5.8 COPS5 "CSN5, JAB1, MOV-34, SGN5" ENSG00000121022 "COP9 signalosome subunit 5" Q92905 8 67043079-67083783 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 347.5;Late spermatids: 427.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004242, HPA004845, HPA051531" Supported Enhanced Nucleoplasm NA NA 37000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004242: AB_627835, HPA004845: AB_1078557, HPA051531: AB_2681522" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-3)" "unprognostic (2.53e-1)" "unprognostic (4.16e-2)" "unprognostic (2.04e-3)" "unprognostic (1.39e-1)" "unprognostic (2.15e-2)" "unprognostic (4.48e-2)" "unprognostic (4.74e-3)" "unprognostic (1.96e-2)" "unprognostic (1.90e-3)" "unprognostic (2.88e-2)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-2)" 43.5 43.8 52.1 33.3 54.2 39.4 45.2 58.3 62.6 34.2 52.0 45.5 45.6 34.0 43.6 42.2 35.6 31.6 100.0 53.2 57.1 56.3 71.0 33.1 40.9 55.1 53.3 33.4 43.0 58.5 31.1 50.9 56.8 36.4 51.6 39.7 42.3 36.6 125.2 36.0 47.8 47.6 57.4 33.4 37.6 58.7 56.2 52.6 37.8 134.9 48.7 42.2 30.0 59.7 104.0 97.8 79.6 74.4 83.1 88.3 63.3 89.0 74.0 121.2 108.9 62.6 125.4 96.5 39.9 93.6 86.8 84.1 109.2 98.9 134.0 92.4 92.1 135.9 95.2 87.3 82.2 86.3 79.1 81.0 126.2 99.1 132.6 95.2 121.2 100.3 163.0 64.6 111.8 96.5 154.3 157.6 107.1 217.2 108.6 97.2 56.7 76.4 131.3 91.6 48.6 66.7 51.0 98.4 91.6 71.2 160.9 90.8 89.9 60.1 74.9 74.7 70.3 81.4 108.5 127.7 89.1 97.6 84.1 65.8 52.0 64.5 35.8 55.7 37.2 36.8 34.6 39.9 63.9 33.7 36.1 32.4 38.3 51.9 56.6 34.0 53.2 43.8 52.1 54.2 58.3 62.6 53.2 57.1 55.1 53.3 56.8 57.4 56.2 59.7 55.0 22.4 26.0 19.2 40.6 49.3 45.1 102.6 28.5 36.4 43.7 51.8 119.9 58.6 61.2 31.3 33.3 143.8 58.0 38.1 88.0 73.4 347.5 44.6 38.2 46.4 34.2 69.2 21.5 60.0 101.4 45.2 25.5 37.1 36.1 50.9 34.2 35.5 79.3 25.2 21.5 41.5 59.0 31.7 28.5 427.2 43.2 40.2 28.4 10.3 59.9 62.0 56.7 18.6 32.4 50.1 48.6 51.1 46.6 54.0 87.8 81.9 46.1 53.0 32.9 49.1 87.8 123.4 49.6 42.9 47.5 127.8 42.3 72.5 55.4 50.6 COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 37.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 50.7;Kupffer cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056599: AB_2683184, HPA068727: AB_2686022" "unprognostic (8.26e-2)" "unprognostic (7.40e-3)" "unprognostic (3.95e-3)" "unprognostic (1.55e-1)" "unprognostic (9.22e-2)" "unprognostic (5.59e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.56e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (2.46e-1)" 6.0 17.0 2.8 8.0 3.2 11.8 5.8 3.5 3.3 7.9 3.6 14.2 9.5 6.3 7.5 10.4 4.4 4.3 15.0 3.0 3.5 5.6 13.6 7.9 6.4 3.6 3.5 6.5 6.5 6.0 4.0 8.4 3.8 6.6 14.2 4.0 7.8 5.0 29.1 10.8 9.1 6.9 4.1 10.1 5.5 3.5 3.9 3.6 5.7 37.5 7.1 7.9 6.5 4.9 26.1 14.7 14.1 27.4 10.5 11.9 9.7 16.1 27.0 29.7 34.4 10.5 38.7 17.2 11.7 28.4 24.6 18.6 23.9 26.0 38.7 17.2 14.8 15.3 22.3 15.4 11.7 31.3 73.5 15.9 16.3 14.2 24.8 8.9 30.7 9.7 10.0 21.4 29.3 27.4 8.6 21.7 10.9 30.6 19.9 14.1 11.4 22.1 45.4 13.8 10.3 6.3 19.0 24.5 9.2 6.7 15.4 18.8 21.0 14.6 14.6 11.1 23.4 5.7 5.2 10.2 29.5 36.8 20.2 2.1 28.8 4.0 2.7 26.8 1.9 6.2 3.0 2.5 21.1 6.9 2.1 3.2 9.8 6.7 33.5 11.2 4.1 13.6 2.8 3.2 3.5 3.3 3.0 3.5 3.6 3.5 3.8 4.1 3.9 4.9 5.4 0.0 4.2 15.7 11.5 6.6 12.4 9.8 4.6 5.9 6.3 5.6 19.5 2.8 10.7 9.2 0.0 25.4 7.1 14.0 31.3 6.7 0.8 7.6 19.5 6.1 4.8 14.1 12.8 10.8 30.0 9.0 6.6 9.2 0.0 17.2 9.3 15.0 50.7 1.7 20.1 15.3 8.2 53.2 7.9 0.8 3.7 25.2 7.2 33.7 21.8 12.6 6.2 25.6 15.6 5.4 15.4 4.9 4.3 12.6 11.0 9.9 6.2 4.8 0.0 7.3 9.7 18.1 19.7 16.7 12.6 12.4 9.6 35.5 26.7 12.9 COQ5 MGC4767 ENSG00000110871 "Coenzyme Q5, methyltransferase" Q5HYK3 12 120503279-120534434 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049487 Approved Uncertain Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Mitochondria "HPA049487: AB_2680789" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (6.30e-3)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (1.60e-1)" "unprognostic (2.01e-2)" "unprognostic (6.20e-2)" "unprognostic (1.62e-1)" "unprognostic (8.37e-2)" "unprognostic (3.79e-2)" "unprognostic (2.02e-1)" "unprognostic (7.73e-2)" "unprognostic (2.00e-2)" "unprognostic (3.88e-2)" 22.7 29.9 22.3 15.9 25.3 11.3 24.1 24.5 29.0 19.7 26.7 24.7 23.4 17.9 23.0 20.4 22.2 14.4 40.7 22.1 23.4 38.9 60.7 15.4 23.3 24.9 24.2 20.5 20.6 21.6 18.1 23.3 24.8 18.9 24.7 26.3 22.4 15.8 98.5 17.6 20.0 18.2 22.8 21.1 19.3 24.7 24.3 22.3 25.7 69.2 23.4 17.2 17.6 29.5 35.7 56.1 49.2 14.2 63.5 48.5 33.7 42.3 27.6 42.5 26.9 22.5 29.2 35.6 48.8 44.7 29.9 37.7 44.2 47.2 43.3 45.4 26.3 47.4 35.0 37.8 51.8 52.2 28.7 46.8 50.2 40.0 46.1 66.0 38.0 67.5 47.4 25.3 49.7 46.9 30.3 60.0 43.2 25.4 43.2 55.9 49.8 52.0 55.2 26.7 37.0 29.8 30.7 15.5 58.3 51.2 77.8 42.6 37.9 29.1 33.4 21.8 28.5 53.9 48.5 40.5 33.3 48.9 35.8 28.6 44.3 32.3 39.7 44.9 39.0 45.6 42.4 43.2 61.0 52.7 56.8 45.5 9.3 60.6 43.5 40.3 57.2 54.4 22.3 25.3 24.5 29.0 22.1 23.4 24.9 24.2 24.8 22.8 24.3 29.5 14.4 12.8 12.8 7.2 15.5 7.8 11.5 33.5 10.8 12.6 17.5 15.2 30.5 18.6 18.1 14.7 14.6 73.0 12.9 16.1 46.9 32.3 59.8 17.8 12.1 15.4 15.0 17.5 5.7 20.0 45.6 16.5 11.7 11.3 17.2 24.0 15.4 42.4 46.3 5.0 7.8 17.0 22.4 12.8 10.1 23.1 16.4 13.6 23.2 3.7 29.0 18.0 23.7 6.6 17.5 11.0 23.9 18.8 11.0 11.2 35.8 66.7 22.4 15.6 6.6 16.3 14.4 34.7 14.8 14.3 8.9 58.3 15.0 32.8 28.1 10.9 COQ6 CGI-10 ENSG00000119723 "Coenzyme Q6, monooxygenase" Q9Y2Z9 14 73949926-73963670 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 167.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051371 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "HPA051371: AB_2681459" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.26e-2)" "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "unprognostic (2.88e-1)" "unprognostic (1.75e-2)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (8.33e-3)" "unprognostic (9.45e-3)" "unprognostic (2.90e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.19e-1)" "unprognostic (1.94e-1)" "unprognostic (7.46e-2)" "unprognostic (1.89e-1)" 11.2 38.4 10.5 5.6 11.0 5.5 12.0 10.9 13.1 12.1 15.5 13.0 10.2 10.0 11.3 10.1 10.5 6.7 32.0 10.8 11.1 23.0 25.7 7.4 6.3 10.6 10.6 11.5 7.0 25.1 15.9 8.0 10.6 12.6 9.5 5.8 11.1 9.9 38.6 9.3 10.8 9.8 10.7 11.3 13.4 22.0 11.0 7.3 12.3 42.6 7.0 13.6 10.5 11.1 12.2 21.7 11.1 25.7 13.2 10.7 15.4 14.8 13.6 21.8 18.4 16.4 21.0 10.7 13.7 15.3 15.0 19.1 16.6 14.8 20.6 16.3 13.3 7.2 12.8 14.3 18.0 7.2 24.9 18.1 19.2 19.9 19.5 14.1 13.9 21.5 6.4 9.6 19.2 33.3 12.4 11.7 4.0 24.8 26.0 11.7 14.1 7.6 22.9 15.2 16.6 8.8 25.2 21.5 14.6 7.2 36.4 13.3 9.4 24.8 22.9 19.0 10.8 8.9 9.0 9.0 13.7 10.6 17.1 5.4 11.3 9.2 11.3 14.2 11.3 10.3 11.2 11.3 12.1 5.3 15.6 9.4 2.3 14.5 13.1 8.9 7.6 8.5 10.5 11.0 10.9 13.1 10.8 11.1 10.6 10.6 10.6 10.7 11.0 11.1 11.9 25.6 25.5 6.2 11.4 4.7 8.1 26.9 6.8 18.9 12.3 12.4 10.3 11.5 23.1 12.9 12.5 26.3 4.1 8.3 19.6 10.8 167.0 14.1 11.0 9.1 4.8 7.4 10.0 10.9 12.6 11.9 12.2 9.9 25.3 13.9 11.4 14.7 16.2 20.2 10.0 9.7 20.3 5.4 4.2 49.5 10.8 7.5 10.6 3.7 9.6 12.0 15.5 5.0 8.4 8.6 8.4 12.4 10.6 6.0 23.3 41.3 15.8 28.1 19.7 10.5 20.5 24.7 21.0 11.5 6.0 23.8 11.9 39.9 9.4 7.1 COQ7 "CAT5, CLK-1" ENSG00000167186 "Coenzyme Q7, hydroxylase" Q99807 16 19067614-19080095 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 40.4;neutrophil: 126.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 126.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067252, HPA071922" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Nucleoplasm "HPA067252: AB_2685813, HPA071922: AB_2686473" "unprognostic (1.37e-1)" "unprognostic (6.89e-3)" "unprognostic (1.59e-2)" "unprognostic (6.08e-2)" "unprognostic (2.44e-2)" "unprognostic (9.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-2)" "unprognostic (1.15e-1)" "unprognostic (7.27e-3)" "unprognostic (2.15e-1)" "unprognostic (8.32e-2)" "prognostic favorable (8.23e-12)" "unprognostic (2.19e-1)" "unprognostic (2.76e-1)" "unprognostic (3.14e-2)" "unprognostic (5.27e-2)" 10.2 13.6 10.7 7.0 11.2 4.8 13.4 10.9 11.6 10.8 12.5 14.1 12.4 15.6 12.3 12.4 15.5 10.7 23.4 11.0 10.8 14.1 12.3 10.0 8.3 10.6 11.3 20.0 10.3 24.4 9.7 10.0 11.1 17.7 13.2 14.0 10.4 14.7 45.8 7.9 11.8 11.6 10.4 10.0 12.8 20.9 11.3 10.3 16.2 44.9 8.4 10.3 8.8 13.1 23.5 24.8 21.1 12.4 11.6 12.2 17.7 13.5 11.0 18.0 18.5 15.9 19.1 17.8 63.9 10.4 19.4 24.5 29.6 16.9 13.0 15.2 29.9 9.5 22.8 49.3 14.4 22.9 20.1 10.3 14.6 16.8 12.2 14.8 14.8 20.9 26.4 16.2 12.9 42.4 24.0 18.4 16.1 9.1 13.1 29.0 23.3 22.8 15.7 15.5 30.4 17.4 12.6 27.4 16.2 10.2 25.2 30.7 16.3 19.0 10.9 14.1 19.7 15.0 26.2 19.7 20.4 13.1 12.5 40.4 11.4 17.8 9.9 10.6 9.4 16.3 8.9 8.7 12.6 15.3 12.2 10.8 126.5 12.9 12.3 15.6 6.2 5.6 10.7 11.2 10.9 11.6 11.0 10.8 10.6 11.3 11.1 10.4 11.3 13.1 13.3 16.0 12.6 6.2 35.5 11.0 26.3 20.9 13.6 31.2 18.3 21.1 21.8 31.5 14.9 16.5 39.6 21.2 28.7 38.1 45.0 25.2 14.8 23.7 16.2 16.1 24.0 4.8 6.0 18.0 17.9 14.9 32.1 23.2 25.4 31.1 20.7 11.1 23.3 20.2 8.8 39.0 30.5 29.4 12.9 8.5 18.6 18.8 10.6 4.7 11.6 39.5 8.2 5.0 9.4 13.2 30.4 13.9 11.6 17.8 71.5 23.7 24.4 53.9 19.7 20.0 20.2 81.3 53.1 12.8 12.4 32.2 23.9 38.2 39.8 24.0 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 56.9" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 69.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 44.0" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in some" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Yes No "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.4 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 2.1 0.6 0.3 0.1 4.5 0.6 0.9 1.4 4.5 56.9 0.0 0.3 1.0 0.1 1.9 0.0 0.7 0.6 0.5 0.2 1.1 1.9 0.4 0.1 2.3 0.0 0.3 0.4 6.1 0.1 7.5 0.3 0.7 0.1 1.1 0.5 2.5 0.3 0.1 0.1 0.1 0.1 1.2 3.9 0.1 0.0 0.0 0.1 0.3 10.3 44.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.7 0.6 0.1 0.1 0.3 0.1 0.3 0.0 7.5 1.0 0.0 3.8 0.3 0.0 0.0 1.0 8.3 0.3 69.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 1.3 1.0 0.0 0.0 6.5 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.8 0.0 0.0 0.6 5.5 2.0 4.7 0.1 5.4 1.0 0.0 0.7 0.0 2.0 3.9 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.3 0.0 0.3 2.3 4.6 4.4 0.1 2.7 0.0 0.6 0.1 0.0 0.3 COX14 "C12orf62, MGC14288" ENSG00000178449 "Cytochrome c oxidase assembly factor COX14" Q96I36 12 50112082-50120457 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 835.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044618, HPA062014" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044618: AB_10960419, HPA062014: AB_2684657" "unprognostic (5.71e-2)" "unprognostic (1.86e-2)" "unprognostic (1.43e-1)" "unprognostic (4.04e-1)" "unprognostic (1.87e-2)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (4.20e-3)" "prognostic unfavorable (7.90e-4)" "unprognostic (7.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.09e-3)" "unprognostic (3.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-3)" 124.0 106.4 96.3 47.1 101.4 66.2 105.6 110.3 129.7 63.6 120.1 92.4 83.4 46.2 130.5 68.5 54.9 62.9 238.6 94.5 105.5 143.8 145.4 62.3 74.5 102.6 99.8 52.8 62.0 127.8 88.0 54.7 102.9 67.0 77.5 60.6 84.9 80.7 247.6 49.8 84.0 58.7 102.9 66.9 76.5 32.6 104.0 54.9 87.3 276.7 62.0 74.2 47.3 110.2 78.4 168.3 32.8 79.4 169.4 105.7 60.5 61.1 92.7 98.8 89.5 156.7 109.1 69.9 171.9 78.3 82.6 79.0 57.2 87.5 91.7 78.7 236.6 154.3 140.4 139.2 65.1 112.1 133.7 123.8 129.9 67.1 76.7 100.5 96.2 83.1 70.2 153.4 109.1 193.3 93.7 170.3 51.5 116.4 211.3 77.6 52.4 176.8 155.0 149.1 91.0 51.4 92.4 177.5 195.6 72.6 115.1 103.6 75.2 55.0 58.1 92.3 50.1 106.3 199.0 93.5 77.9 105.0 30.9 258.8 197.8 172.7 146.1 194.5 155.6 213.7 186.9 167.0 190.0 188.0 176.7 173.7 67.0 153.1 178.2 247.2 224.8 214.8 96.3 101.4 110.3 129.7 94.5 105.5 102.6 99.8 102.9 102.9 104.0 110.2 91.5 60.9 120.6 11.1 108.8 124.9 91.2 212.9 87.0 68.2 169.2 192.5 524.4 161.5 138.7 222.5 22.9 191.9 111.1 320.9 565.4 131.4 7.1 117.5 58.7 99.2 156.0 69.2 13.1 170.1 122.6 90.3 81.6 88.1 65.4 64.0 88.9 397.9 219.6 47.1 16.3 214.7 187.2 152.3 110.4 22.9 129.2 117.7 149.4 6.5 181.2 111.0 111.2 7.1 22.3 116.8 262.4 109.4 93.0 129.5 492.6 835.5 157.5 67.4 105.2 51.5 130.8 51.1 56.0 121.6 159.3 127.5 112.2 115.4 227.4 118.6 COX17 ENSG00000138495 "Cytochrome c oxidase copper chaperone COX17" Q14061 3 119654513-119677454 "Cancer-related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042226, HPA048158" Supported Supported Mitochondria NA NA 220000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA042226: AB_2677911, HPA048158: AB_2680292" "unprognostic (1.98e-2)" "unprognostic (3.49e-2)" "unprognostic (1.96e-2)" "unprognostic (8.29e-2)" "unprognostic (2.88e-2)" "unprognostic (6.63e-3)" "unprognostic (3.49e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-1)" "unprognostic (7.11e-3)" "unprognostic (2.12e-1)" "unprognostic (4.45e-2)" "unprognostic (1.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.65e-1)" "unprognostic (9.19e-2)" "unprognostic (2.64e-2)" 81.6 178.5 106.5 77.1 111.2 113.3 68.8 117.5 122.4 50.3 149.2 90.2 90.2 41.2 114.1 55.9 47.3 59.4 279.9 105.5 123.6 94.7 172.7 62.3 110.4 115.8 115.3 31.5 102.0 412.1 119.2 63.9 115.7 78.6 78.7 120.6 80.8 90.7 401.4 43.3 88.5 62.9 112.5 64.9 107.5 44.4 113.0 106.6 94.4 363.9 89.8 75.9 35.7 118.6 219.6 257.0 122.7 33.3 53.4 53.1 45.7 130.5 84.2 127.3 133.4 226.4 157.7 164.6 158.0 72.1 174.8 84.0 138.5 154.9 74.9 205.5 155.9 145.0 195.3 180.1 63.1 205.0 246.7 56.6 142.7 77.9 106.0 82.2 87.9 200.8 122.4 370.7 155.4 410.2 212.8 283.5 133.8 212.2 413.3 88.3 82.3 273.7 203.2 141.0 210.5 86.4 153.1 137.1 189.7 76.9 180.5 313.0 66.6 91.3 144.9 59.8 168.4 257.5 348.9 361.1 129.0 157.8 164.2 591.4 241.1 630.6 218.1 357.5 208.1 378.3 241.7 230.3 252.8 320.4 189.1 187.0 174.4 213.6 487.3 538.7 352.6 260.1 106.5 111.2 117.5 122.4 105.5 123.6 115.8 115.3 115.7 112.5 113.0 118.6 194.5 157.0 167.1 5.2 161.5 94.1 132.8 267.9 46.7 108.9 153.8 147.2 622.8 238.8 202.4 498.4 43.8 137.4 116.7 385.3 716.1 264.0 115.0 282.4 64.3 164.7 214.2 162.9 3.8 413.7 193.9 99.3 150.3 178.8 309.3 70.2 116.0 779.8 216.1 75.7 5.6 327.8 427.2 181.8 281.2 39.9 91.0 190.8 277.5 11.2 345.7 178.8 137.0 8.5 8.8 459.7 512.8 136.9 176.5 198.2 434.6 786.2 280.2 174.4 184.1 112.9 171.6 286.0 159.2 85.4 125.4 211.0 129.0 49.6 151.1 199.0 COX18 FLJ38991 ENSG00000163626 "Cytochrome c oxidase assembly factor COX18" Q8N8Q8 4 73052362-73069755 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046772, HPA049489" Approved NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA046772: AB_2679799, HPA049489: AB_2680791" "unprognostic (3.32e-3)" "unprognostic (2.01e-1)" "prognostic favorable (6.31e-4)" "unprognostic (9.01e-3)" "unprognostic (2.43e-1)" "unprognostic (2.17e-1)" "unprognostic (3.81e-2)" "unprognostic (6.97e-2)" "unprognostic (2.92e-1)" "unprognostic (5.29e-3)" "unprognostic (1.58e-3)" "unprognostic (2.85e-2)" "prognostic favorable (8.22e-7)" "unprognostic (1.28e-2)" "unprognostic (2.94e-1)" "unprognostic (5.80e-2)" "unprognostic (1.22e-3)" 1.5 3.9 0.7 0.4 0.8 0.5 1.4 1.3 1.0 1.3 1.1 1.6 0.6 1.5 0.9 1.4 1.2 0.4 2.7 0.8 0.9 1.7 2.4 1.2 0.7 0.4 0.6 1.5 2.0 0.7 1.3 0.6 0.5 0.9 0.6 1.3 1.9 0.6 2.7 1.3 1.4 0.4 0.3 1.3 1.7 1.3 1.0 0.4 1.1 1.2 0.5 1.2 1.2 0.7 0.6 1.0 1.0 1.0 0.9 0.9 0.8 1.0 0.9 0.4 0.5 0.8 1.1 1.8 0.7 0.6 0.7 0.6 1.0 0.7 0.4 1.4 0.7 0.9 1.3 1.3 0.7 1.5 1.2 1.1 0.7 0.4 0.8 1.1 0.8 1.6 1.4 1.7 0.8 0.5 1.8 1.0 1.5 1.1 1.1 1.0 1.6 2.6 0.8 0.6 1.5 1.0 1.1 0.9 0.4 0.8 0.8 0.8 1.1 1.0 0.8 1.3 0.5 1.7 0.8 1.1 1.2 1.1 0.8 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.1 0.1 0.7 0.8 1.3 1.0 0.8 0.9 0.4 0.6 0.5 0.3 1.0 0.7 5.6 3.2 6.3 7.2 10.1 2.5 3.7 4.5 1.2 11.7 7.1 4.2 13.9 5.7 7.3 9.2 22.9 8.0 9.0 5.5 13.7 6.5 4.0 6.7 8.4 6.7 5.4 7.8 10.5 8.0 8.3 7.0 5.6 7.1 0.0 17.4 11.4 16.7 8.8 20.2 10.6 7.7 4.1 13.9 3.0 2.0 9.0 8.4 5.4 6.5 12.5 6.6 11.3 10.1 13.4 9.3 5.2 9.4 18.1 6.6 6.6 13.0 8.1 14.3 13.1 7.5 6.0 10.2 7.3 5.5 1.4 3.0 8.6 12.7 9.6 3.4 COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1151.3;skeletal muscle: 1332.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3614.3;Distal tubular cells: 3621.5;Proximal enterocytes: 2795.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034517 Supported Enhanced Mitochondria NA NA 230000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034517: AB_10603561" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.73e-4)" 209.1 252.9 323.0 42.8 339.7 113.3 178.7 373.1 436.0 138.1 349.2 322.6 164.2 124.6 72.3 284.6 136.9 32.6 1151.3 319.2 357.2 478.6 372.8 120.4 40.3 341.7 339.9 138.4 165.6 234.0 169.0 47.1 339.9 158.2 113.4 74.5 196.7 90.1 1332.7 213.2 211.9 51.1 332.9 153.2 290.6 101.2 353.1 64.4 185.0 705.9 54.3 179.8 179.1 355.3 144.9 165.5 106.8 169.7 115.9 105.8 428.3 180.0 100.8 118.3 130.5 459.9 148.7 240.8 377.3 116.5 188.4 217.9 117.5 181.8 56.4 188.7 493.2 324.2 166.6 559.8 220.3 310.6 231.2 193.8 161.6 113.4 91.2 125.4 104.4 187.8 243.6 115.5 94.0 360.0 203.5 450.0 196.6 257.2 854.3 194.9 170.6 368.8 167.5 227.9 202.2 210.3 175.0 225.0 374.8 146.0 115.7 345.5 186.9 107.5 181.4 174.4 118.7 265.8 274.7 183.1 194.9 264.5 113.5 1086.6 1062.7 933.1 458.0 1057.0 445.1 801.5 547.4 481.8 990.1 666.0 528.0 468.8 1016.6 469.6 926.3 677.6 783.4 1543.0 323.0 339.7 373.1 436.0 319.2 357.2 341.7 339.9 339.9 332.9 353.1 355.3 461.0 221.2 256.0 33.3 292.7 386.6 629.5 1166.0 377.9 239.1 433.2 536.2 3614.3 567.6 618.5 800.0 227.2 736.0 257.4 1960.0 3621.5 599.5 207.5 399.4 300.8 380.0 740.3 308.8 27.3 604.1 897.1 391.6 616.7 439.7 330.6 392.2 361.3 1234.9 875.0 141.3 33.7 1430.5 1043.6 485.2 651.9 360.8 351.6 456.6 912.4 30.0 711.7 461.5 314.1 15.6 39.4 505.4 1836.0 304.6 353.3 468.2 2795.9 2663.5 485.4 386.3 447.0 340.2 569.9 265.2 310.7 944.2 479.9 613.2 291.9 455.7 1576.9 915.9 COX6A2 ENSG00000156885 "Cytochrome c oxidase subunit 6A2" Q02221 16 31427731-31428360 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 46 "heart muscle: 3905.3;skeletal muscle: 6742.0;tongue: 2096.1" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 4861.8" "Group enriched" "Detected in many" 5 "head and neck cancer: 9.3;liver cancer: 2.9;prostate cancer: 3.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 150 "NK-cell: 15.0" "Lineage enriched" "Detected in single" 150 "NK-cells: 15.0" "Cell line enriched" "Detected in some" 4 "U-266/84: 13.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.66e-1)" "unprognostic (1.73e-3)" "unprognostic (2.09e-2)" "unprognostic (1.25e-2)" "unprognostic (1.68e-2)" "unprognostic (3.88e-1)" "unprognostic (5.61e-2)" "unprognostic (7.20e-2)" "unprognostic (8.71e-2)" "unprognostic (6.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.65e-1)" 1.9 0.9 1.8 0.1 1.3 0.0 2.9 2.3 2.3 0.4 0.2 1.4 1.1 1.0 0.0 74.8 0.9 0.0 3905.3 0.9 2.1 4.5 15.9 3.3 0.4 1.6 2.6 1.2 3.0 2.9 11.9 0.1 7.3 38.9 0.0 1.0 92.1 0.1 6742.0 3.5 1.2 0.0 0.8 0.5 1.3 1.3 2.6 0.5 2.0 2096.1 0.1 0.3 1.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.1 1.8 1.3 2.3 2.3 0.9 2.1 1.6 2.6 7.3 0.8 2.6 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.4 4861.8 2.8 0.0 3.7 0.0 0.0 0.4 0.0 5.9 0.0 0.0 0.0 0.1 48.8 0.0 0.0 0.0 0.4 0.0 96.2 0.0 0.1 0.0 0.2 0.4 75.7 2.9 3.3 0.0 0.1 0.0 1.6 0.0 0.8 0.3 1.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.1 1.3 24.9 0.0 4.2 19.7 258.0 53.7 0.2 1.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014295, CAB016244" Enhanced Supported Mitochondria NA NA 210000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB016244: AB_2085703, HPA014295: AB_2668966" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (6.90e-2)" "unprognostic (3.37e-2)" "unprognostic (1.58e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-2)" "unprognostic (1.29e-1)" "unprognostic (3.51e-1)" "unprognostic (3.70e-1)" "unprognostic (8.86e-2)" "unprognostic (3.47e-3)" "unprognostic (1.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" 134.0 147.5 180.8 52.9 183.9 152.6 125.7 186.1 291.0 166.4 190.2 268.1 334.8 194.0 175.6 197.3 189.5 20.4 781.6 191.8 195.6 254.9 328.5 108.4 71.1 186.0 188.4 161.9 107.3 101.7 159.5 89.9 189.2 162.6 110.4 147.0 108.1 58.1 666.1 121.4 172.3 42.7 182.4 122.9 180.0 170.8 192.7 44.8 129.1 554.1 51.5 188.7 148.6 188.9 137.6 57.8 63.8 251.3 140.0 100.5 103.1 44.5 42.7 30.1 34.3 54.7 284.5 326.8 320.1 70.1 47.7 176.4 36.4 363.3 51.0 60.5 89.1 684.6 66.9 160.4 88.9 319.3 201.9 95.1 475.3 26.0 56.4 129.2 45.1 103.8 49.8 571.1 51.6 134.2 337.9 289.6 117.9 205.5 127.7 381.0 21.2 320.6 453.4 713.3 191.8 115.2 30.9 654.2 351.5 65.0 461.7 201.1 40.1 220.4 286.0 235.8 63.8 140.7 126.3 209.6 310.2 128.2 200.8 345.8 134.7 114.1 177.8 210.5 189.0 209.7 270.6 193.5 212.9 189.8 319.7 294.9 16.6 187.7 266.5 301.9 272.7 252.9 180.8 183.9 186.1 291.0 191.8 195.6 186.0 188.4 189.2 182.4 192.7 188.9 527.8 403.8 485.1 29.7 382.1 490.8 493.5 1431.9 279.4 217.6 561.3 642.7 2146.4 491.8 731.2 605.1 102.2 978.9 416.1 1263.2 2226.5 673.6 834.3 579.3 778.7 436.9 807.5 400.2 27.6 849.4 853.9 502.0 440.4 551.9 362.5 219.3 384.1 1855.5 1066.5 156.5 33.5 1221.3 1027.4 451.1 539.5 266.5 664.8 440.8 732.8 23.4 778.0 545.0 449.0 22.6 32.1 808.6 1338.7 587.5 412.2 448.4 2173.5 1791.0 702.9 282.0 493.0 367.1 555.9 1180.5 505.2 666.4 640.6 1784.9 452.1 428.0 1246.7 715.5 COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 18 "heart muscle: 2260.5;skeletal muscle: 6947.0;tongue: 4960.0" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 21879.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 162.5;ASC TERT1: 122.3;BJ: 84.7;BJ hTERT+: 102.7;fHDF/TERT166: 178.6;HHSteC: 91.4;HSkMC: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "unprognostic (6.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (7.84e-3)" "unprognostic (7.27e-3)" "unprognostic (9.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-2)" 269.2 91.5 197.5 20.4 198.8 2.1 105.9 195.3 256.5 70.6 197.2 122.8 14.9 54.6 39.3 82.3 57.8 31.9 2260.5 210.0 214.7 86.9 11.9 63.3 12.0 197.7 188.7 46.0 40.6 147.8 105.6 27.4 199.5 86.6 23.7 49.7 88.0 119.1 6947.0 33.8 36.7 85.1 192.1 34.4 46.7 9.7 200.0 85.8 54.8 4960.0 7.3 88.5 50.1 217.9 0.5 5.9 0.6 0.1 162.5 122.3 0.0 84.7 102.7 3.4 0.0 0.0 1.8 1.4 13.0 178.6 0.0 0.7 0.0 0.0 0.8 0.2 1.8 0.4 2.1 0.3 91.4 0.0 0.8 109.0 0.0 0.0 0.0 0.0 11.3 0.0 0.6 0.7 0.0 0.8 0.0 0.7 1.0 0.6 1.2 0.2 0.0 0.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.1 20.7 0.0 1.3 0.5 0.4 0.8 1.9 0.7 0.2 0.8 1.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 197.5 198.8 195.3 256.5 210.0 214.7 197.7 188.7 199.5 192.1 200.0 217.9 309.7 0.0 5.1 2.3 2.2 26.4 1.0 28.2 2.8 80.6 25.0 89.4 21879.1 18.6 11.0 22.0 45.9 1.0 1.5 0.0 817.8 13.7 17.0 6.0 124.6 360.4 0.0 5.3 5.9 14.1 0.7 602.1 0.5 3.7 45.0 5.5 259.5 7.3 24.0 67.3 4.3 0.0 26.4 10.7 30.5 90.8 224.6 5.2 284.6 3.7 0.0 31.5 0.0 2.0 2.3 6.2 0.0 281.3 1.5 3.5 0.0 183.1 10.7 84.7 184.1 328.4 463.4 2.0 3.8 4.3 19.0 1.9 4.8 17.3 0.1 0.8 COX7A2 "COX7AL, COXVIIa-L" ENSG00000112695 "Cytochrome c oxidase subunit 7A2" 6 75237675-75250323 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 4705.1;Late spermatids: 3873.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (8.49e-2)" "unprognostic (2.56e-1)" "unprognostic (1.98e-2)" "unprognostic (2.15e-2)" "unprognostic (1.34e-1)" "unprognostic (5.67e-3)" "unprognostic (1.00e-1)" "unprognostic (1.65e-1)" "unprognostic (7.70e-2)" "unprognostic (2.73e-3)" "unprognostic (7.44e-2)" "unprognostic (1.74e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" 180.5 204.2 346.7 94.5 356.4 171.8 166.2 374.6 579.3 133.0 382.9 314.4 196.3 128.4 215.0 253.0 135.7 105.5 601.8 357.5 401.2 374.6 307.6 146.1 117.3 344.1 349.7 103.8 154.1 407.8 232.6 92.4 355.2 163.4 327.9 332.2 160.4 124.0 185.3 163.6 200.9 158.5 358.6 138.6 286.4 497.7 353.5 166.6 146.8 293.8 156.6 160.5 154.1 378.4 116.5 260.5 334.6 276.7 195.9 220.0 242.3 276.9 252.7 270.3 291.3 471.1 172.9 188.1 239.0 251.9 363.1 247.1 236.1 299.9 336.8 347.8 482.6 283.6 842.1 630.6 200.8 305.6 319.9 240.7 392.7 250.9 163.2 283.4 318.7 420.8 255.2 266.0 370.4 536.6 130.7 329.7 210.9 569.4 472.5 210.2 169.0 500.7 436.3 745.0 228.2 275.3 172.4 312.0 301.7 273.2 190.9 843.6 156.4 118.8 218.2 95.9 319.5 373.2 444.7 221.4 135.7 342.5 237.3 693.0 582.0 585.0 435.6 663.4 468.5 659.6 563.3 527.9 619.7 559.7 551.1 511.9 437.7 496.6 696.0 781.4 680.8 1055.8 346.7 356.4 374.6 579.3 357.5 401.2 344.1 349.7 355.2 358.6 353.5 378.4 370.9 304.5 371.3 15.0 391.8 553.7 624.1 2000.6 268.6 251.0 584.8 693.0 2518.6 630.5 1019.4 503.9 120.9 686.3 348.5 1504.8 2602.2 800.4 4705.1 460.2 288.0 382.5 663.0 354.3 18.9 1007.3 787.6 367.5 414.9 451.7 300.1 269.4 385.8 1485.8 870.3 154.8 22.4 1283.5 1468.9 484.8 499.6 3873.2 355.7 420.2 846.6 10.3 715.3 390.3 396.5 14.1 20.9 1157.5 1498.6 339.3 593.7 848.5 1790.7 2008.3 772.8 359.9 407.6 303.7 587.8 2905.4 230.0 627.9 626.4 818.3 381.9 336.4 1242.8 994.8 COX7C ENSG00000127184 "Cytochrome c oxidase subunit 7C" P15954 5 86617928-86620962 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2380.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4586.0;Distal tubular cells: 4724.9;Proximal tubular cells: 5650.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046647 Approved NA NA 39000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA046647: AB_2679736" "unprognostic (1.45e-1)" "unprognostic (1.74e-2)" "unprognostic (9.10e-2)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (1.04e-1)" "unprognostic (3.70e-1)" "unprognostic (4.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-2)" "unprognostic (1.21e-1)" "prognostic favorable (1.23e-5)" "unprognostic (4.56e-2)" "unprognostic (2.06e-1)" "unprognostic (1.46e-1)" "unprognostic (4.46e-2)" 338.6 433.9 600.9 274.3 610.7 314.7 324.9 620.1 771.4 329.2 657.2 563.0 545.8 271.8 402.9 420.1 288.0 194.7 1546.9 609.6 648.8 715.2 621.3 243.3 314.5 619.9 616.5 392.7 382.2 781.1 402.4 196.2 613.5 305.4 398.2 236.6 459.7 253.1 2380.2 274.3 537.4 207.5 614.4 270.0 429.7 174.6 624.6 370.8 328.0 1599.4 319.8 344.4 315.0 614.7 576.6 687.2 595.1 1043.0 551.4 550.5 653.4 432.8 364.4 298.2 416.7 806.4 989.9 794.6 459.2 342.3 799.3 594.8 539.3 876.2 487.2 585.2 829.5 623.6 1006.0 844.4 458.9 732.2 692.1 648.0 745.3 377.5 518.0 841.6 486.3 687.0 392.7 860.9 443.7 1209.9 766.2 954.2 594.7 593.0 1958.6 728.4 654.3 1426.2 909.4 1129.8 700.4 518.2 406.7 946.9 973.0 646.9 963.0 1008.6 449.2 254.2 470.5 448.4 846.6 832.8 1056.8 903.4 652.5 860.4 491.6 344.5 526.0 414.6 399.1 558.3 500.0 682.6 620.5 497.6 668.6 567.2 648.4 579.2 52.3 404.7 538.3 619.0 606.5 996.5 600.9 610.7 620.1 771.4 609.6 648.8 619.9 616.5 613.5 614.4 624.6 614.7 408.8 512.8 732.9 33.0 879.5 723.5 946.8 1663.7 715.4 276.2 1141.9 1079.4 4586.0 1574.2 959.9 1213.8 156.4 1271.2 657.5 1604.6 4724.9 1314.8 1011.8 856.3 538.7 570.2 916.6 651.1 24.6 1506.3 878.3 605.7 677.3 706.8 618.0 814.7 809.2 2748.0 1388.3 230.5 30.2 1829.4 933.8 1457.0 904.7 488.5 985.7 785.3 1115.3 18.7 1443.9 714.6 782.7 15.1 25.9 1114.6 1964.4 720.7 617.5 975.5 3353.2 5650.8 734.8 313.3 598.2 662.7 740.8 927.7 381.9 1319.3 935.4 1320.8 826.7 634.8 2108.4 1356.3 CPT2 "CPT1, CPTASE" ENSG00000157184 "Carnitine palmitoyltransferase 2" P23786 1 53196792-53214197 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.2" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 85.1;Hepatocytes: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028201, HPA028202, HPA028214" Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" Nucleoli "HPA028201: AB_10599177, HPA028202: AB_10599942, HPA028214: AB_10601958" "unprognostic (2.43e-1)" "unprognostic (2.27e-1)" "prognostic favorable (5.27e-4)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (9.34e-2)" "unprognostic (6.48e-2)" "unprognostic (1.75e-2)" "unprognostic (2.86e-1)" "unprognostic (1.67e-1)" "unprognostic (3.00e-2)" "unprognostic (8.97e-2)" "prognostic favorable (1.46e-12)" "unprognostic (4.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.95e-2)" 12.9 14.3 6.6 9.4 8.2 5.4 13.6 7.9 7.3 10.3 16.8 35.4 32.4 6.8 10.5 14.2 10.5 9.5 19.5 6.1 7.1 35.1 91.2 11.5 10.6 8.1 7.5 10.2 21.7 27.3 6.7 18.0 8.0 12.2 32.8 7.1 14.6 11.7 17.3 6.7 24.9 11.4 7.7 8.7 18.4 12.9 9.0 10.2 12.5 33.1 13.2 11.1 4.5 8.9 16.0 8.3 17.2 17.8 14.6 11.3 17.5 9.8 13.2 17.5 17.5 8.6 14.5 28.9 14.6 9.2 20.1 19.1 35.1 25.1 15.1 17.0 16.0 21.8 9.9 6.4 25.9 15.9 19.5 23.0 23.2 13.8 11.1 18.6 15.4 26.5 20.9 9.9 13.1 12.8 10.7 13.0 29.8 38.4 20.0 13.2 16.2 34.4 22.9 22.0 25.3 14.4 22.1 30.3 39.7 36.6 32.3 32.2 8.7 8.4 6.1 16.5 8.5 26.3 19.8 16.2 11.6 20.6 12.4 5.6 14.1 14.6 7.2 20.0 8.1 5.3 6.3 8.4 17.9 7.4 10.5 7.2 5.3 6.9 20.5 8.9 9.9 10.3 6.6 8.2 7.9 7.3 6.1 7.1 8.1 7.5 8.0 7.7 9.0 8.9 5.0 12.8 24.1 4.2 7.8 1.8 5.2 20.5 5.2 6.0 7.5 7.0 18.1 15.7 11.4 11.0 14.6 85.1 4.5 49.3 25.4 12.9 1.1 10.9 8.1 5.9 14.5 9.4 1.5 10.5 20.3 7.2 18.3 10.3 2.5 12.7 8.9 88.8 26.3 15.2 2.0 26.6 16.2 15.1 7.2 2.8 6.8 10.5 7.2 1.9 20.2 11.6 6.2 2.5 4.5 10.5 25.6 5.3 9.1 4.9 38.6 41.0 7.6 11.0 6.6 7.5 8.4 49.9 31.3 13.8 2.6 54.6 6.9 25.6 29.5 5.7 CPTP "GLTPD1, MGC10334" ENSG00000224051 "Ceramide-1-phosphate transfer protein" Q5TA50 1 1324756-1328896 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 72.5;Late spermatids: 167.1;Proximal enterocytes: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056832 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA056832: AB_2683251" "unprognostic (9.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (7.01e-2)" "unprognostic (1.94e-2)" "unprognostic (1.37e-1)" "unprognostic (1.90e-1)" "unprognostic (3.35e-1)" "unprognostic (1.52e-2)" "unprognostic (1.32e-2)" "unprognostic (2.79e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.27e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-2)" "unprognostic (5.27e-2)" 15.7 19.5 14.1 6.0 13.0 2.8 16.9 13.1 22.1 17.6 14.0 28.3 19.8 14.2 8.5 48.9 12.5 3.7 92.8 15.0 10.9 28.4 69.9 12.6 5.4 16.0 13.8 10.8 18.6 14.1 8.0 4.6 17.1 19.1 4.8 2.0 37.2 6.5 55.2 33.0 23.2 2.7 12.3 21.2 31.3 70.7 15.4 4.0 14.2 22.8 4.4 14.7 24.8 11.8 36.0 12.7 6.0 11.0 5.7 4.8 9.7 18.4 9.8 17.1 11.1 17.4 19.6 14.2 20.9 8.5 11.3 26.3 4.8 10.9 6.2 16.8 16.5 10.6 13.6 17.7 14.4 10.3 10.3 9.3 8.3 18.0 5.0 8.3 9.1 9.0 15.8 8.3 5.7 13.3 11.4 12.1 5.5 9.3 55.1 14.0 9.8 41.1 14.0 9.5 14.2 14.9 14.8 46.3 32.8 3.1 16.5 7.1 15.5 18.3 12.8 20.1 15.2 18.1 14.8 14.8 17.6 15.1 5.6 1.8 1.2 6.1 1.6 0.6 0.9 2.9 1.9 1.5 0.8 1.5 1.1 0.9 1.6 1.2 1.2 1.2 5.1 1.4 14.1 13.0 13.1 22.1 15.0 10.9 16.0 13.8 17.1 12.3 15.4 11.8 20.0 0.0 3.2 2.0 7.2 0.0 7.8 0.0 5.2 9.7 15.8 8.6 22.6 12.8 1.3 7.3 0.0 18.6 10.8 35.3 39.2 25.9 72.5 5.9 4.9 13.8 6.1 5.5 3.0 24.3 21.3 7.0 26.5 9.4 0.0 9.1 13.9 31.5 16.4 23.5 3.3 14.0 0.0 7.6 0.0 167.1 12.2 6.3 0.0 5.6 15.8 16.3 18.6 2.0 2.7 49.3 13.3 9.8 18.6 12.0 72.0 18.2 0.0 7.0 13.1 4.7 6.8 52.3 4.8 14.0 0.0 19.6 7.5 9.8 18.4 9.1 CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.5;tongue: 201.3" "Cell type enhanced" "Detected in many" "Early spermatids: 181.2;Late spermatids: 521.8;Proximal enterocytes: 136.4;Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Nucleoplasm,Nuclear membrane" NA NA 8100 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_2732427" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favorable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" 36.1 51.3 26.4 5.4 26.6 9.0 29.2 27.0 33.8 31.7 27.5 36.1 33.0 24.8 4.0 37.3 23.1 6.6 68.2 25.1 27.8 46.9 151.2 15.2 3.2 28.8 28.2 23.0 107.1 26.3 12.3 6.6 30.6 42.2 4.2 1.7 32.8 8.9 227.5 29.6 37.2 6.8 26.7 15.2 34.0 146.4 30.2 3.1 21.5 201.3 1.6 31.3 27.5 24.4 0.1 39.3 10.7 21.3 13.4 25.9 17.0 15.0 16.6 18.9 12.0 7.8 14.0 1.5 9.2 25.9 23.2 6.7 2.2 4.9 7.2 23.6 0.3 7.3 19.1 30.4 34.1 0.0 26.1 26.3 0.0 15.7 0.9 15.8 26.2 7.2 3.6 5.7 20.0 9.1 0.5 15.9 2.8 32.0 18.0 16.8 21.8 12.2 18.0 0.6 4.2 12.1 0.0 7.1 4.8 3.4 49.7 5.5 22.6 23.0 1.6 32.1 15.4 25.5 22.6 0.1 28.8 4.2 16.8 1.6 8.4 3.5 3.2 5.5 6.7 1.5 4.4 4.3 8.6 1.3 2.6 3.1 1.1 4.4 5.6 3.9 4.5 6.1 26.4 26.6 27.0 33.8 25.1 27.8 28.8 28.2 30.6 26.7 30.2 24.4 10.5 6.4 3.7 5.5 4.9 3.2 4.7 10.8 0.6 1.5 9.7 8.1 57.8 21.5 8.2 3.7 2.1 45.9 6.0 64.5 17.6 22.6 181.2 3.5 15.7 12.9 15.5 17.4 5.3 22.4 55.6 19.3 16.8 9.9 7.0 12.9 14.6 65.7 20.7 1.7 6.1 23.6 14.2 13.9 10.5 521.8 22.1 12.4 5.4 6.5 8.3 15.5 6.2 3.5 4.0 11.6 47.6 24.5 9.6 9.3 136.4 52.0 2.8 1.3 6.6 10.5 15.7 123.5 8.6 57.4 4.5 50.3 7.6 20.1 29.3 13.8 CRIP2 "CRP2, ESP1" ENSG00000182809 "Cysteine rich protein 2" P52943 14 105472962-105480162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 1113.7" "Cell type enhanced" "Detected in many" "Adipocytes: 459.4;Cardiomyocytes: 863.3;Endothelial cells: 510.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 52.1;memory CD4 T-cell: 80.4;naive B-cell: 109.9;T-reg: 115.6" "Group enriched" "Detected in all" 30 "B-cells: 109.9;T-cells: 115.6" "Cell line enhanced" "Detected in many" "EFO-21: 321.9;MCF7: 306.5;SK-BR-3: 303.7;T-47d: 266.4;TIME: 259.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042664 Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA 160000 "Cluster 26: Non-specific - Mitochondria" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoli "Nucleoplasm, Plasma membrane" "HPA042664: AB_10797017" "unprognostic (2.68e-1)" "unprognostic (6.53e-3)" "unprognostic (2.11e-3)" "unprognostic (2.19e-1)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.63e-2)" "unprognostic (2.56e-1)" "unprognostic (3.20e-3)" "unprognostic (9.68e-2)" "unprognostic (6.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (6.25e-2)" "unprognostic (2.35e-2)" "unprognostic (2.39e-2)" "unprognostic (8.26e-3)" 177.6 44.7 160.4 31.3 172.0 1.5 162.5 137.7 259.5 101.6 124.2 101.9 27.0 138.1 36.4 127.3 130.0 47.9 1113.7 172.7 186.4 205.1 52.7 185.7 30.0 157.3 158.7 51.2 46.1 19.2 175.0 49.6 158.6 89.0 8.3 4.1 100.0 72.9 52.5 128.9 82.8 32.0 145.0 104.1 66.1 92.8 191.9 10.4 155.6 42.7 16.5 121.4 100.4 140.8 2.5 201.2 37.9 98.3 4.3 19.9 10.0 17.5 1.9 2.8 1.0 7.1 44.2 0.2 321.9 73.8 4.5 166.8 3.6 50.8 0.1 2.3 1.9 0.2 132.5 73.8 24.3 0.0 25.5 10.5 4.4 5.2 26.2 38.4 192.7 0.2 0.5 1.4 26.8 306.5 0.5 0.6 10.0 45.7 143.4 0.4 7.7 9.9 140.1 0.6 61.6 175.3 30.0 303.7 1.9 4.9 266.4 0.1 259.3 82.7 38.8 2.3 50.5 0.7 0.6 0.9 24.3 0.3 179.3 0.2 1.9 0.0 7.5 0.9 6.8 52.1 80.4 17.2 3.6 109.9 17.8 4.5 1.0 3.7 0.5 0.5 115.6 10.4 160.4 172.0 137.7 259.5 172.7 186.4 157.3 158.7 158.6 145.0 191.9 140.8 459.4 157.0 33.7 17.9 15.0 153.2 96.7 206.4 29.0 2.7 110.0 140.7 863.3 107.2 127.1 189.4 4.2 2.6 8.2 0.9 154.6 106.8 37.9 125.1 28.8 510.4 25.2 9.7 16.4 87.6 30.5 132.9 32.1 126.6 7.6 0.4 346.3 30.4 3.0 94.2 3.0 0.3 81.4 11.8 92.6 84.0 28.0 9.3 156.5 27.2 2.5 57.2 1.0 4.5 3.1 48.9 0.1 14.7 7.0 37.4 0.2 17.0 155.7 4.0 276.1 108.1 339.5 27.8 46.1 20.1 196.8 32.0 32.5 5.9 0.2 103.2 CRIP3 "bA480N24.2, TLP, TLP-A" ENSG00000146215 "Cysteine rich protein 3" Q6Q6R5 6 43299710-43308826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 24.3;testis: 25.7" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Distal tubular cells: 9.8;Granulosa cells: 12.5;Late spermatids: 7.9;Oligodendrocyte precursor cells: 6.6" "Cancer enhanced" "Detected in some" "liver cancer: 3.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 16 "myeloid DC: 44.6" "Lineage enriched" "Detected in many" 16 "dendritic cells: 44.6" "Cell line enhanced" "Detected in some" "HAP1: 2.8;HEK 293: 3.3;HeLa: 3.5;Hep G2: 6.5;NTERA-2: 5.7;RPMI-8226: 4.6;THP-1: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036198 Uncertain Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA036198: AB_10670791" "unprognostic (8.35e-3)" "unprognostic (4.14e-3)" "unprognostic (6.37e-2)" "unprognostic (5.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.07e-2)" "unprognostic (1.18e-1)" "unprognostic (2.30e-2)" "unprognostic (4.34e-2)" "unprognostic (1.46e-2)" "unprognostic (8.49e-4)" "unprognostic (1.86e-2)" "unprognostic (7.30e-3)" "unprognostic (5.02e-2)" "unprognostic (4.89e-2)" "unprognostic (4.46e-2)" "unprognostic (2.80e-4)" 0.8 0.6 10.1 1.7 10.2 2.6 0.9 11.3 16.5 2.4 8.1 1.1 2.0 1.3 1.6 0.7 2.0 0.6 24.3 10.1 10.4 5.3 10.4 0.6 5.4 9.4 9.4 2.1 1.6 2.1 2.3 0.2 9.4 5.7 0.4 2.5 0.8 8.0 0.4 1.8 3.5 0.6 9.0 7.9 0.8 25.7 10.0 1.6 2.0 0.0 5.9 1.1 1.4 10.4 0.0 0.8 0.2 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.2 0.0 0.1 0.6 2.8 0.1 0.0 0.0 3.3 0.0 3.5 6.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.6 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 2.7 0.9 0.0 1.7 0.0 2.3 0.0 0.0 44.6 2.6 0.0 0.0 0.8 0.3 2.3 0.4 0.0 1.8 10.1 10.2 11.3 16.5 10.1 10.4 9.4 9.4 9.4 9.0 10.0 10.4 0.2 0.0 0.0 9.4 2.8 0.6 0.3 0.0 0.0 0.9 0.1 0.8 3.2 5.7 0.1 0.0 0.0 0.0 0.1 0.3 9.8 1.1 3.9 1.1 0.2 0.2 0.0 0.8 4.7 0.2 0.0 0.2 0.0 0.1 0.0 12.5 0.0 2.9 0.2 0.0 3.5 0.1 0.0 0.9 3.4 7.9 1.2 0.7 0.0 1.0 1.4 0.5 1.0 6.6 3.4 0.3 0.1 0.0 0.1 0.1 0.7 4.5 0.3 0.8 0.0 0.3 0.4 5.3 1.6 0.0 0.0 0.0 0.3 1.0 0.4 0.1 CRLS1 "C20orf155, CLS1, dJ967N21.6, GCD10" ENSG00000088766 "Cardiolipin synthase 1" Q9UJA2 20 6006093-6040053 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 169.5" "Cell type enhanced" "Detected in all" "Early spermatids: 264.2;Hepatocytes: 208.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 237.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.88e-1)" "unprognostic (8.56e-2)" "unprognostic (9.64e-3)" "unprognostic (1.89e-1)" "unprognostic (1.41e-2)" "unprognostic (2.65e-2)" "unprognostic (1.42e-1)" "unprognostic (2.00e-1)" "unprognostic (9.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-2)" "unprognostic (1.83e-2)" "unprognostic (1.85e-1)" "unprognostic (9.54e-2)" "prognostic favorable (8.02e-4)" 50.1 55.1 14.7 16.9 14.9 28.4 33.2 14.4 17.9 24.0 16.7 32.3 59.2 18.9 19.9 18.5 24.1 19.9 82.8 14.5 14.7 57.8 169.5 27.1 16.5 15.5 15.9 21.2 37.4 28.3 15.8 17.9 15.3 32.6 32.9 15.5 27.5 25.8 86.0 15.1 40.9 23.7 15.3 14.5 46.5 27.8 16.9 16.9 27.2 79.5 18.3 25.8 17.7 15.4 71.7 46.5 27.9 40.0 83.1 74.9 34.5 43.6 50.9 38.8 46.8 61.5 44.4 75.8 31.4 52.6 73.3 45.0 54.6 70.9 57.6 21.9 39.9 99.5 17.0 237.4 59.6 99.7 32.4 44.6 59.4 41.5 73.5 36.8 57.3 40.3 76.4 31.6 44.2 25.9 63.6 90.1 55.4 154.8 42.4 42.3 44.6 80.7 61.8 22.1 50.3 43.4 44.8 98.7 78.1 27.5 35.8 59.6 39.2 45.9 33.4 48.7 59.0 33.8 79.1 79.9 17.6 79.5 43.9 0.0 1.2 0.6 1.2 0.9 2.2 2.3 0.7 0.8 1.3 1.1 1.4 0.8 0.0 1.7 0.5 1.6 0.8 0.4 14.7 14.9 14.4 17.9 14.5 14.7 15.5 15.9 15.3 15.3 16.9 15.4 18.8 22.4 47.6 22.2 26.4 33.8 41.4 19.4 31.9 12.9 35.8 27.7 108.0 64.3 16.2 36.8 4.2 45.1 19.5 36.3 64.6 27.9 264.2 29.7 26.2 22.7 28.6 58.0 37.0 28.8 64.1 33.8 52.0 29.7 14.7 31.6 22.5 208.7 34.2 11.8 28.7 50.7 4.1 40.0 24.1 99.5 30.4 31.9 26.6 32.8 28.9 40.5 25.7 39.7 34.3 28.4 49.1 24.5 41.8 117.7 75.7 141.0 15.0 12.9 13.1 29.2 25.6 23.0 18.4 37.7 27.8 36.3 23.3 32.3 82.9 48.6 CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 141.9;Horizontal cells: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" Cytosol "HPA037577: AB_10672497" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (1.31e-2)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "prognostic favorable (6.82e-5)" "unprognostic (1.48e-3)" "unprognostic (1.67e-1)" "unprognostic (5.07e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.01e-1)" "prognostic favorable (6.44e-15)" "unprognostic (8.13e-3)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-1)" 31.8 22.3 33.3 8.9 35.3 29.4 27.1 36.4 36.9 24.4 22.8 26.5 10.8 23.3 16.9 15.9 29.1 17.4 60.0 36.6 29.3 22.5 62.7 22.9 10.4 27.4 31.5 38.7 34.7 22.4 30.8 13.5 28.5 25.3 9.9 52.8 21.7 22.1 96.7 50.4 16.7 17.1 28.8 14.0 24.6 34.4 35.2 12.6 34.0 64.8 10.3 26.0 18.4 31.4 1.4 4.2 6.3 7.5 16.7 8.4 13.8 5.0 8.9 6.2 4.5 6.8 3.3 9.8 3.8 10.5 5.9 8.5 6.0 5.2 4.3 9.8 5.5 6.4 8.2 9.4 6.4 8.0 8.5 9.9 7.5 4.8 7.6 7.0 4.4 7.5 12.7 16.2 5.6 5.3 6.8 9.4 17.1 17.8 5.0 11.5 9.1 4.6 4.5 7.8 10.1 3.8 8.3 7.5 4.5 8.0 10.0 5.5 5.5 8.7 5.3 13.5 3.6 15.0 10.8 7.9 5.3 3.5 5.3 4.1 3.5 5.4 5.7 4.8 4.7 5.0 5.5 6.1 3.6 4.6 6.6 6.9 1.8 7.5 8.0 2.6 4.9 5.3 33.3 35.3 36.4 36.9 36.6 29.3 27.4 31.5 28.5 28.8 35.2 31.4 11.7 12.8 18.2 48.0 12.6 17.0 9.7 5.1 8.0 141.9 10.6 8.6 34.7 14.3 11.6 7.3 27.1 8.0 10.0 17.2 29.4 5.4 24.2 28.1 7.5 9.2 7.1 3.0 30.3 4.7 5.6 19.8 12.8 15.4 14.7 10.8 8.6 47.3 3.6 101.0 26.0 7.4 6.1 8.5 12.5 8.7 31.4 7.2 16.0 10.3 6.2 34.4 10.3 13.0 13.6 6.0 6.0 39.9 8.5 11.6 10.5 11.6 23.8 27.5 19.7 14.5 14.6 29.1 15.0 4.4 17.5 9.3 9.1 8.4 6.0 9.8 CRYM DFNA40 ENSG00000103316 "Crystallin mu" Q14894 16 21238874-21303083 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.7;heart muscle: 175.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.0;Ionocytes: 114.0;Muller glia cells: 640.7;Proximal tubular cells: 190.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 21 "plasmacytoid DC: 82.0" "Lineage enriched" "Detected in many" 21 "dendritic cells: 82.0" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 100.3" "Group enriched" "Detected in all" 11 "amygdala: 124.0;basal ganglia: 275.1;cerebral cortex: 124.7;hippocampal formation: 324.3;white matter: 128.4" "Low region specificity" "Detected in all" "HPA019086, HPA030619" Enhanced Supported Cytosol NA NA 150000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA019086: AB_1847260, HPA030619: AB_2673551" "unprognostic (1.32e-1)" "unprognostic (2.93e-3)" "unprognostic (8.96e-2)" "unprognostic (1.44e-1)" "unprognostic (2.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.88e-1)" "unprognostic (5.75e-3)" "unprognostic (2.81e-1)" "unprognostic (7.37e-2)" "unprognostic (2.05e-2)" "unprognostic (5.95e-2)" "unprognostic (2.11e-3)" "unprognostic (7.79e-3)" "unprognostic (2.49e-2)" "unprognostic (1.87e-3)" "unprognostic (1.31e-1)" 1.9 0.8 37.4 0.9 78.7 1.0 2.7 40.6 62.2 3.7 13.6 6.9 1.6 1.0 0.2 7.6 1.1 7.0 175.3 54.0 31.6 64.4 14.2 8.5 1.1 13.9 19.8 0.3 1.8 8.9 55.6 0.4 15.6 35.4 8.4 54.7 20.6 0.2 13.4 4.1 2.6 0.3 14.1 0.3 1.3 5.1 20.5 0.3 0.4 0.9 3.8 21.8 3.6 31.3 0.2 4.0 0.0 0.0 0.2 0.4 0.7 0.0 2.1 0.1 0.2 0.2 0.2 0.3 1.0 0.0 1.8 0.6 5.4 0.0 0.0 0.0 0.8 23.2 0.1 2.3 0.0 0.1 2.2 0.8 0.0 0.8 1.0 0.0 0.0 0.5 0.0 0.4 0.7 0.3 0.0 0.9 9.7 1.6 0.1 0.1 0.0 0.5 100.3 0.1 3.7 5.2 0.2 0.1 2.6 4.8 0.1 0.0 0.0 0.5 0.7 6.8 0.0 0.2 0.0 0.5 16.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.1 3.9 0.0 0.0 0.3 0.0 0.0 82.0 0.0 1.2 37.4 78.7 40.6 62.2 54.0 31.6 13.9 19.8 15.6 14.1 20.5 31.3 0.3 0.0 20.1 5.2 4.1 2.3 25.4 16.3 0.0 6.3 0.4 11.7 126.0 2.8 56.1 14.7 4.2 0.0 11.4 7.1 17.6 0.1 19.7 3.2 1.5 3.0 13.1 4.8 43.8 0.0 0.0 7.1 6.1 7.7 1.3 1.3 0.4 8.3 0.1 1.7 5.9 20.6 114.0 1.6 0.7 12.4 0.0 1.5 33.8 10.3 0.7 640.7 0.0 7.1 6.6 0.4 2.8 0.0 0.3 19.0 7.5 190.1 19.9 26.2 0.0 0.2 4.3 6.7 7.3 0.2 1.3 0.1 1.1 0.1 8.2 68.0 CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 550.1;tongue: 600.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 670000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB075750: AB_2665756, CAB075751: AB_2665757, CAB075752: AB_2665758, CAB075753: AB_2665759, CAB075754: AB_2665760, HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" 154.2 93.6 29.2 61.7 30.0 111.0 66.3 33.7 49.9 55.4 40.5 110.1 97.7 56.4 32.2 95.6 58.3 42.4 319.3 30.9 34.6 86.6 39.0 58.0 67.2 39.4 32.0 56.0 61.5 127.6 28.9 45.7 39.4 59.0 124.1 128.9 73.7 60.5 550.1 70.5 81.2 77.5 22.5 49.0 66.5 24.4 41.0 69.4 53.0 600.7 106.1 70.2 58.2 31.6 168.9 176.8 141.6 198.2 188.4 173.8 93.3 136.9 132.0 231.1 160.6 271.2 158.2 322.9 128.2 172.6 99.3 182.1 396.8 200.8 234.9 109.3 200.2 222.9 136.1 261.4 107.3 288.4 166.6 188.2 201.6 182.4 232.0 202.2 268.6 163.7 233.2 193.7 214.7 160.8 229.8 121.9 117.5 128.0 247.8 222.3 167.1 247.6 166.2 194.6 189.3 125.2 175.2 251.7 157.7 137.5 297.6 174.3 178.3 127.1 165.3 167.4 147.4 124.5 200.4 206.2 120.4 206.4 119.5 59.6 73.3 205.7 47.0 93.0 61.9 60.6 56.5 45.1 119.3 51.8 59.2 47.9 31.3 51.6 94.0 65.6 63.4 71.2 29.2 30.0 33.7 49.9 30.9 34.6 39.4 32.0 39.4 22.5 41.0 31.6 14.5 16.0 39.5 32.3 31.6 39.0 23.5 26.9 46.7 22.8 38.3 29.7 239.9 15.7 21.5 12.9 62.6 18.5 24.1 66.9 35.2 32.5 6.6 25.1 31.5 27.2 16.9 36.0 21.5 45.1 31.3 25.8 42.3 53.5 27.9 21.3 18.9 29.7 34.3 10.1 24.6 43.9 20.3 39.4 35.0 4.8 20.2 34.6 10.6 9.4 44.8 16.7 16.5 18.6 18.8 44.6 35.7 19.9 46.7 33.1 50.4 22.0 14.9 38.3 13.1 27.8 38.2 29.7 25.8 74.8 52.1 16.8 25.8 32.0 71.3 34.5 CTF1 "CT-1, CT1" ENSG00000150281 "Cardiotrophin 1" Q16619 16 30896614-30903547 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 16.4;Cardiomyocytes: 11.4;Distal tubular cells: 31.3;Muller glia cells: 21.1;Proximal tubular cells: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.6;ASC TERT1: 14.7;fHDF/TERT166: 11.9;HHSteC: 13.0;HSkMC: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025853 Uncertain "Secreted to blood" NA NA 11900 "Cluster 6: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "CAB025853: " "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (6.81e-3)" "unprognostic (1.06e-3)" "prognostic unfavorable (7.22e-5)" "unprognostic (2.12e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.87e-4)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (6.75e-2)" "unprognostic (2.76e-2)" "unprognostic (1.76e-3)" "unprognostic (5.07e-3)" "unprognostic (2.06e-1)" "unprognostic (2.16e-2)" "unprognostic (1.79e-1)" 6.4 8.1 4.8 1.3 4.7 1.5 6.7 4.1 5.2 14.7 5.3 13.4 0.8 17.3 4.2 5.3 12.1 3.8 16.0 4.5 4.5 10.2 1.2 7.4 1.3 5.3 5.8 18.4 3.6 10.0 5.2 2.0 4.7 12.2 1.0 2.1 5.7 12.7 14.1 2.7 4.6 7.6 5.5 1.7 7.6 3.4 5.0 2.1 8.5 10.9 1.1 14.0 9.6 5.0 2.0 0.3 2.6 5.7 13.6 14.7 4.5 4.3 8.5 4.4 5.6 2.4 0.4 0.1 8.3 11.9 0.4 1.5 0.0 3.0 4.4 0.1 0.2 0.1 0.2 0.9 13.0 0.2 0.8 13.9 3.8 3.3 8.0 4.9 1.2 0.2 3.7 0.4 7.9 0.3 0.3 0.4 0.8 1.2 0.8 1.6 3.9 0.0 0.7 0.9 0.2 1.4 0.0 0.1 0.0 4.0 6.9 0.3 0.9 4.2 5.2 0.2 0.1 0.1 0.1 0.2 3.3 0.5 0.0 0.6 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.1 0.3 0.0 0.0 4.8 4.7 4.1 5.2 4.5 4.5 5.3 5.8 4.7 5.5 5.0 5.0 0.8 3.2 6.4 2.6 0.8 0.4 16.4 1.8 2.2 0.3 6.2 7.1 11.4 2.8 1.8 7.3 0.0 0.3 1.2 0.0 31.3 1.0 0.6 7.1 2.9 1.1 0.0 0.4 0.3 0.4 0.2 3.9 0.0 2.4 0.0 3.8 0.0 0.4 0.6 0.0 0.6 0.2 0.0 0.6 0.8 0.7 2.1 1.1 0.0 1.0 0.4 21.1 0.0 1.0 0.4 0.4 0.0 2.6 0.6 2.7 0.2 14.4 2.5 0.9 0.0 4.6 3.0 0.8 0.4 1.9 0.3 0.4 0.7 3.9 0.2 7.4 CTNNA3 "MGC26194, VR22" ENSG00000183230 "Catenin alpha 3" Q9UI47 10 65912523-67696195 "Disease related genes, Predicted intracellular proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 176.3" "Cell type enriched" "Detected in some" 14 "Oligodendrocytes: 4054.6" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.4;Karpas-707: 1.5;NTERA-2: 1.7;RPMI-8226: 2.4;SCLC-21H: 1.5;U-266/70: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061818 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA061818: AB_2684618" "unprognostic (2.19e-1)" "unprognostic (1.57e-1)" "unprognostic (8.64e-4)" "unprognostic (8.13e-3)" "unprognostic (6.43e-3)" "unprognostic (9.90e-2)" "unprognostic (2.60e-4)" "unprognostic (8.27e-2)" "unprognostic (5.10e-2)" "unprognostic (2.55e-1)" "unprognostic (9.09e-3)" "unprognostic (1.15e-1)" "unprognostic (2.67e-3)" "unprognostic (7.93e-5)" "unprognostic (6.43e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" 0.7 0.5 31.8 0.6 96.9 0.1 0.5 49.3 49.7 1.4 0.0 2.0 0.3 1.3 0.1 1.4 0.7 0.6 18.7 30.3 51.6 0.5 8.5 0.1 0.2 90.9 66.8 1.7 0.1 0.2 0.2 0.4 95.3 0.4 0.6 0.4 0.3 0.2 12.0 0.2 0.8 2.6 52.4 0.3 1.2 2.2 69.7 0.1 0.3 23.4 0.3 0.6 0.6 176.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 1.7 0.6 0.7 0.1 0.0 2.4 0.0 0.0 1.5 0.0 0.1 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.4 0.0 0.0 6.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 31.8 96.9 49.3 49.7 30.3 51.6 90.9 66.8 95.3 52.4 69.7 176.3 0.4 0.0 0.0 24.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 75.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 217.8 0.0 1.5 1.2 0.0 0.0 49.8 0.0 0.0 2.5 0.0 0.1 0.0 2.6 0.4 5.7 0.0 0.0 50.6 0.0 0.0 0.8 0.3 275.5 4.4 0.3 0.0 30.0 0.0 1.4 0.0 50.3 4054.6 0.0 0.1 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 9.3 4.0 1.6 0.0 0.1 0.0 0.1 4.6 0.1 0.0 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CTXND1 LINC01314 ENSG00000259417 "Cortexin domain containing 1" A0A1B0GTU2 15 80195481-80252213 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 30.9;liver: 9.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 6.3;Proximal tubular cells: 14.0" "Group enriched" "Detected in many" 7 "glioma: 3.4;liver cancer: 2.7;melanoma: 9.1;thyroid cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-MEL-30: 1.6;WM-115: 4.7" "Region enriched" "Detected in all" 4 "hippocampal formation: 35.0" NA NA "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (4.15e-5)" "unprognostic (8.42e-2)" "unprognostic (6.08e-2)" "unprognostic (1.86e-3)" "unprognostic (5.59e-2)" "unprognostic (3.48e-1)" "unprognostic (1.90e-2)" "unprognostic (2.61e-1)" "unprognostic (2.41e-1)" "unprognostic (7.04e-2)" "unprognostic (3.90e-4)" "unprognostic (2.43e-1)" "unprognostic (1.72e-2)" "unprognostic (1.92e-3)" "unprognostic (1.06e-1)" "unprognostic (5.14e-3)" "unprognostic (1.34e-1)" 0.3 3.7 11.4 0.2 9.4 0.0 0.2 4.9 14.0 0.3 3.0 0.9 0.4 0.1 5.4 0.1 0.3 0.1 2.7 30.9 9.8 2.2 9.4 1.5 0.2 7.2 11.1 0.4 0.5 0.0 1.4 0.0 8.4 0.3 0.2 1.4 0.1 0.1 0.5 0.8 0.5 0.0 6.4 1.4 2.6 0.4 14.4 0.0 0.4 0.1 0.2 0.5 0.3 6.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.4 4.9 14.0 30.9 9.8 7.2 11.1 8.4 6.4 14.4 6.0 0.0 0.0 6.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 1.9 1.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CXXC4 IDAX ENSG00000168772 "CXXC finger protein 4" 4 104468308-104494901 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 16.1;retina: 7.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 48.0;Cone photoreceptor cells: 31.3;Enteroendocrine cells: 102.1;Horizontal cells: 45.4;Oligodendrocyte precursor cells: 64.3;Oligodendrocytes: 30.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;AN3-CA: 9.7;Karpas-707: 9.0;RPMI-8226: 5.5;SCLC-21H: 12.0;U-266/70: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036600, HPA036925" Uncertain Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Nucleoplasm "HPA036600: AB_10673659, HPA036925: " "unprognostic (1.37e-2)" "unprognostic (1.12e-1)" "unprognostic (5.75e-2)" "unprognostic (5.86e-2)" "unprognostic (9.07e-3)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (9.69e-3)" "unprognostic (2.75e-1)" "unprognostic (2.45e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.82e-1)" "unprognostic (4.52e-3)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.42e-3)" 0.6 1.3 4.9 0.1 3.9 0.0 1.4 3.0 16.1 0.7 0.2 1.3 1.8 0.4 1.7 0.1 2.3 0.3 1.9 4.3 10.1 0.4 0.8 0.6 0.0 5.0 6.1 1.8 3.0 0.7 4.4 0.3 4.5 0.5 0.8 7.3 2.9 0.4 0.3 0.2 1.9 0.4 4.4 0.4 1.3 1.6 11.9 0.5 2.4 0.1 0.0 0.2 0.3 4.8 0.0 0.2 7.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 9.0 0.0 0.0 2.7 0.0 2.5 0.1 0.1 0.0 0.0 5.5 0.0 0.1 12.0 2.2 0.0 0.6 0.0 2.8 0.3 0.0 0.0 0.0 1.5 0.0 0.1 9.7 2.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 3.9 3.0 16.1 4.3 10.1 5.0 6.1 4.5 4.4 11.9 4.8 12.4 0.0 6.4 10.4 0.1 0.3 1.0 0.8 1.2 48.0 8.4 5.6 15.9 2.8 2.2 0.0 31.3 0.2 0.8 0.4 0.0 0.1 0.3 13.0 0.9 2.9 102.1 0.0 23.8 3.3 0.0 1.0 0.0 0.6 0.0 1.2 1.1 2.7 0.1 45.4 27.5 6.2 0.0 0.3 0.3 0.9 0.3 0.1 1.8 0.0 0.0 13.8 1.0 64.3 30.8 1.5 1.2 10.9 0.3 0.6 10.2 1.1 12.6 26.7 0.0 15.6 0.9 0.0 4.8 0.1 0.0 0.3 0.5 0.1 2.6 0.5 CYCS "CYC, HCS" ENSG00000172115 "Cytochrome c, somatic" P99999 7 25118656-25125260 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Electron transport, Respiratory chain, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 799.8" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004222, CAB005126, CAB018597" Enhanced Supported Mitochondria NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "CAB004222: AB_627385, CAB005126: AB_2090472, CAB018597: AB_627383" "unprognostic (3.06e-2)" "unprognostic (3.39e-1)" "unprognostic (3.32e-2)" "unprognostic (4.11e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.81e-4)" "unprognostic (4.44e-2)" "unprognostic (7.04e-3)" "unprognostic (5.67e-2)" "unprognostic (6.22e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.30e-5)" "unprognostic (1.18e-1)" "unprognostic (4.94e-2)" "unprognostic (8.75e-3)" "unprognostic (7.04e-2)" 86.0 115.6 65.8 89.2 70.4 85.0 59.2 79.8 101.7 45.3 87.6 263.6 150.1 42.3 41.5 105.9 43.0 52.9 476.8 72.1 82.8 174.6 115.7 54.3 63.8 71.0 72.9 48.1 38.5 226.2 57.0 43.0 69.4 54.3 238.8 153.9 58.0 60.1 483.7 47.6 120.1 91.1 70.2 48.0 108.1 61.1 83.4 74.0 74.6 799.8 89.4 119.8 60.1 71.7 336.4 185.1 195.0 273.7 108.7 83.1 199.6 314.4 128.0 229.2 264.5 307.4 222.2 383.8 152.9 138.5 678.3 385.8 396.5 295.0 401.2 115.0 179.1 318.6 208.9 218.7 170.2 739.0 271.1 111.2 257.5 230.9 492.9 99.4 209.5 232.2 597.1 397.9 246.0 155.1 408.6 284.4 365.1 746.3 343.0 282.1 235.3 364.5 360.9 322.5 392.6 190.3 164.5 689.0 267.9 338.7 359.5 436.6 152.8 209.3 383.3 329.8 591.8 401.4 507.3 860.5 281.0 526.4 606.7 65.3 56.2 42.8 68.0 106.0 82.5 102.5 62.2 71.6 105.7 90.0 58.6 70.2 8.2 73.3 96.8 81.5 87.5 83.0 65.8 70.4 79.8 101.7 72.1 82.8 71.0 72.9 69.4 70.2 83.4 71.7 244.3 83.3 118.6 42.4 337.6 689.8 818.3 698.5 237.9 163.1 210.6 179.6 770.0 144.4 314.2 183.9 77.2 192.6 304.4 827.5 1663.0 278.3 496.4 154.8 120.2 183.3 384.9 162.6 53.2 216.0 351.0 257.3 287.5 197.5 212.6 68.7 81.0 210.8 353.0 132.9 64.6 522.5 502.5 141.5 715.2 161.8 90.1 329.2 590.5 16.9 245.8 220.9 197.8 17.1 24.2 303.8 570.5 93.6 358.7 551.9 392.8 638.6 146.1 195.2 138.1 294.7 962.3 423.1 211.1 402.7 715.2 349.3 349.7 146.9 600.2 884.1 CYP46A1 CYP46 ENSG00000036530 "Cytochrome P450 family 46 subfamily A member 1" Q9Y6A2 14 99684298-99727301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 96.2" "Cell type enhanced" "Detected in many" "Astrocytes: 58.1;Cone photoreceptor cells: 66.7;Excitatory neurons: 53.0;Inhibitory neurons: 41.6;Rod photoreceptor cells: 28.4" "Cancer enriched" "Detected in single" 5 "glioma: 1.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "plasmacytoid DC: 3.4" "Lineage enriched" "Detected in single" 23 "dendritic cells: 3.4" "Group enriched" "Detected in some" 4 "AF22: 2.4;U-937: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 32: U-937 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (2.16e-1)" "unprognostic (4.30e-1)" "unprognostic (2.50e-5)" "unprognostic (9.48e-5)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (3.45e-2)" "unprognostic (1.06e-1)" "unprognostic (5.37e-2)" "unprognostic (4.01e-2)" "unprognostic (1.32e-5)" "unprognostic (5.21e-2)" "unprognostic (2.44e-4)" "unprognostic (5.97e-4)" "unprognostic (1.59e-1)" "unprognostic (1.15e-2)" "unprognostic (3.88e-3)" 1.9 2.0 45.7 0.3 96.2 0.0 0.8 20.1 66.7 1.4 17.5 0.7 0.2 1.5 0.9 0.2 1.0 0.4 4.7 52.7 34.0 1.4 1.3 0.6 0.6 25.3 32.0 1.6 2.1 1.9 16.6 0.0 26.2 1.4 0.2 5.1 1.4 0.6 1.1 0.4 0.5 0.8 23.5 0.2 0.7 2.5 38.2 0.4 1.7 0.5 0.1 0.9 0.7 39.0 0.0 0.0 2.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 1.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 45.7 96.2 20.1 66.7 52.7 34.0 25.3 32.0 26.2 23.5 38.2 39.0 3.5 3.2 6.0 58.1 0.7 1.7 6.4 0.0 1.2 11.5 1.8 3.3 7.0 2.8 1.8 1.8 66.7 0.2 8.7 0.0 1.9 0.2 0.7 0.9 5.0 7.6 0.0 0.0 53.0 1.1 0.3 4.0 0.5 0.6 1.3 2.1 2.9 3.4 0.6 8.4 41.6 0.0 0.0 2.1 3.0 1.3 4.7 0.9 3.6 6.5 1.1 20.8 0.0 23.6 11.8 0.1 0.1 4.1 2.2 4.1 0.0 7.4 0.9 28.4 0.0 8.1 3.9 9.4 5.3 0.0 1.4 0.1 1.5 2.7 0.1 3.5 DBI "ACBD1, ACBP" ENSG00000155368 "Diazepam binding inhibitor, acyl-CoA binding protein" P07108 2 119366921-119372560 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 2215.1;Proximal tubular cells: 2834.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 2479.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051428 Approved NA NA 9100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA051428: AB_2681482" "unprognostic (1.24e-1)" "prognostic favorable (5.77e-5)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (1.92e-2)" "unprognostic (7.28e-3)" "unprognostic (1.70e-3)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.45e-1)" 358.3 153.9 486.0 158.7 470.8 121.9 717.3 495.6 726.7 218.6 452.3 322.8 312.8 73.5 653.7 667.7 85.8 129.7 515.4 493.0 498.5 536.2 971.1 236.0 182.9 499.4 495.1 86.0 143.8 866.9 76.9 116.3 510.0 451.5 297.3 116.3 369.9 215.1 273.0 451.0 229.6 97.2 512.7 115.5 185.1 201.3 487.6 173.3 133.7 460.5 324.5 136.5 327.7 516.4 543.0 276.9 557.1 257.2 1339.7 1131.9 350.7 281.3 708.7 387.0 746.1 580.6 427.8 747.3 312.1 440.6 938.5 277.9 397.0 588.3 345.9 498.2 262.1 641.4 279.9 775.8 335.6 206.1 2479.2 648.2 376.5 596.2 222.1 255.4 464.3 358.8 77.0 679.2 558.8 559.1 436.5 585.9 370.2 349.7 429.7 157.4 541.4 658.5 948.1 816.5 263.2 210.1 235.3 548.5 634.9 388.8 338.0 952.8 332.5 259.3 329.8 288.8 346.3 220.9 170.5 610.0 365.7 364.8 315.3 1180.7 439.9 1077.9 472.9 489.1 347.3 461.4 367.8 465.2 748.8 505.3 279.1 419.2 285.8 450.7 402.5 791.0 615.7 792.2 486.0 470.8 495.6 726.7 493.0 498.5 499.4 495.1 510.0 512.7 487.6 516.4 505.2 150.6 613.0 46.0 256.7 289.2 249.4 724.2 190.1 37.9 806.5 1025.9 1079.6 663.4 390.0 310.8 14.6 796.5 395.6 737.5 1197.4 466.9 844.4 154.8 194.7 206.2 371.3 108.8 5.2 670.3 643.2 258.2 243.1 185.6 433.4 219.4 167.8 2215.1 1069.4 30.3 3.9 495.0 524.9 305.0 785.7 325.7 152.2 476.1 1058.3 15.0 871.5 928.6 552.0 33.2 25.0 372.7 612.0 127.5 192.0 355.0 753.6 2834.8 340.5 59.1 151.2 267.2 289.9 462.0 30.1 972.6 684.9 516.3 260.8 456.0 673.2 361.0 DCXR "DCR, HCR2, KIDCR, P34H, SDR20C1" ENSG00000169738 "Dicarbonyl and L-xylulose reductase" Q7Z4W1 17 82035136-82037709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Xylose metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 1851.6" "Cell type enhanced" "Detected in all" "Distal tubular cells: 812.0;Hepatocytes: 3510.3;Proximal tubular cells: 2919.4" "Group enriched" "Detected in all" 5 "liver cancer: 305.9;prostate cancer: 163.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 365.2;MCF7: 446.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023371, HPA023863" Enhanced Uncertain Nucleoli,Microtubules NA NA 4000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Microtubules" "HPA023371: AB_1847530, HPA023863: AB_1847531" "unprognostic (3.33e-2)" "unprognostic (1.67e-3)" "unprognostic (3.75e-1)" "unprognostic (1.16e-2)" "unprognostic (1.19e-1)" "unprognostic (8.43e-2)" "unprognostic (4.54e-3)" "unprognostic (1.86e-2)" "unprognostic (3.05e-1)" "unprognostic (2.56e-2)" "prognostic favorable (4.70e-4)" "unprognostic (1.72e-1)" "prognostic favorable (2.13e-4)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.10e-2)" 106.7 43.9 93.1 15.2 95.3 25.3 107.6 102.5 111.1 52.0 84.4 49.6 29.2 39.5 281.3 96.6 59.2 10.8 132.7 87.6 100.7 239.9 1851.6 61.0 16.6 102.4 98.0 70.0 71.6 46.1 63.9 20.2 105.9 138.0 20.9 9.7 103.4 33.6 187.3 87.6 44.4 10.4 91.8 35.8 167.0 44.8 105.9 26.1 60.7 80.6 19.6 48.9 62.1 94.9 50.3 68.2 32.8 56.4 123.2 31.8 80.4 25.0 33.9 68.5 48.4 122.0 21.3 100.3 47.4 35.9 9.4 57.4 59.6 52.6 24.1 21.4 145.9 96.9 48.8 365.2 143.2 75.6 114.5 44.6 62.2 22.7 79.8 16.0 41.1 61.1 112.4 76.3 36.5 446.2 63.7 184.1 35.0 242.9 71.3 57.9 42.0 135.3 53.3 71.9 85.5 51.0 35.5 287.5 46.0 19.7 213.4 74.5 20.5 36.6 45.0 48.9 48.2 73.7 56.2 50.2 31.4 83.0 26.7 49.5 92.6 77.9 66.5 92.0 64.1 86.8 83.0 64.7 151.3 99.2 117.7 85.4 47.2 108.9 88.1 121.6 98.9 110.1 93.1 95.3 102.5 111.1 87.6 100.7 102.4 98.0 105.9 91.8 105.9 94.9 29.0 51.3 198.2 16.6 133.6 58.5 200.3 113.5 109.8 16.0 301.8 269.2 120.7 183.0 123.4 178.4 18.8 372.1 116.6 152.9 812.0 41.4 6.0 67.0 50.9 44.6 54.7 335.7 4.7 42.6 450.6 65.0 151.4 102.3 64.7 62.7 138.5 3510.3 164.7 21.9 9.0 170.4 189.2 165.7 65.6 22.6 70.8 82.3 179.7 1.9 52.8 145.1 78.2 5.5 10.5 30.4 135.7 47.4 98.6 215.2 158.9 2919.4 55.4 26.5 19.7 40.6 79.6 10.3 48.2 219.9 73.2 342.6 135.7 118.6 154.6 178.8 DDO ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.4;Muller glia cells: 8.2;Oligodendrocytes: 13.3;Paneth cells: 8.5;Proximal enterocytes: 8.5;Proximal tubular cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.5;RPMI-8226: 15.9;U-937: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" 1.9 8.2 4.5 0.8 7.0 1.4 2.5 5.0 4.8 1.9 4.3 2.3 7.4 2.1 2.7 0.8 4.9 2.9 18.4 4.4 4.5 10.6 11.1 3.2 1.0 5.4 4.9 0.3 2.6 5.3 1.2 1.6 5.3 2.0 3.2 2.4 4.2 2.3 10.9 0.4 7.0 2.2 4.8 2.1 1.1 0.1 4.7 0.4 1.3 7.4 0.2 1.6 0.9 5.9 0.2 0.0 0.0 0.1 0.0 0.2 1.1 0.1 5.4 1.3 0.9 0.0 0.1 0.0 0.7 0.7 11.5 0.0 0.0 0.0 2.3 5.0 0.0 5.1 0.1 4.3 1.6 0.0 0.0 0.1 0.0 2.7 0.1 2.3 0.0 0.0 0.0 1.9 4.5 0.0 0.0 0.2 0.0 0.0 0.1 0.1 3.0 15.9 0.0 4.9 0.1 0.2 0.0 0.5 0.6 0.0 0.7 1.1 0.9 1.0 0.1 0.0 2.6 0.1 0.4 0.0 2.0 17.4 0.0 0.0 2.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 1.1 1.0 0.0 0.0 1.1 4.5 7.0 5.0 4.8 4.4 4.5 5.4 4.9 5.3 4.8 4.7 5.9 1.1 0.0 0.0 4.9 0.0 0.0 0.7 0.7 0.6 0.0 1.4 1.1 17.4 0.0 0.4 0.0 2.1 0.2 0.1 1.8 3.9 4.5 0.3 3.6 0.5 0.7 4.2 0.0 0.0 2.2 0.2 0.6 0.0 0.9 0.0 0.1 2.5 4.9 1.7 0.0 0.1 6.0 0.0 3.1 0.4 0.0 0.3 1.6 0.0 0.0 2.0 8.2 0.0 3.5 13.3 0.8 8.5 0.0 0.0 0.4 8.5 12.9 2.2 0.2 0.0 2.1 1.2 0.0 0.0 0.2 0.0 0.0 0.2 0.3 5.0 0.5 DGCR6 ENSG00000183628 "DiGeorge syndrome critical region gene 6" Q14129 22 18906028-18914238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 63.8;skeletal muscle: 183.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1045.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.3" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 8 "OE19: 46.5" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (9.80e-3)" "unprognostic (2.12e-3)" "unprognostic (1.51e-1)" "unprognostic (3.93e-3)" "unprognostic (2.41e-1)" "unprognostic (3.14e-1)" "unprognostic (1.60e-1)" "unprognostic (1.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (5.77e-2)" "unprognostic (2.23e-2)" "unprognostic (3.38e-2)" "unprognostic (8.08e-2)" "unprognostic (3.11e-1)" "unprognostic (1.28e-1)" 15.9 10.0 6.6 0.7 6.5 2.0 15.0 8.7 7.3 6.5 8.3 3.9 1.4 2.1 2.3 7.3 4.0 1.1 63.8 6.5 6.6 11.0 27.1 9.6 1.7 7.4 6.2 2.2 13.1 1.7 19.9 1.3 7.5 6.9 0.9 4.5 12.6 1.5 183.4 26.3 5.0 0.8 5.3 4.2 5.5 26.2 7.1 1.4 21.9 7.0 1.4 4.7 7.9 7.4 0.7 2.5 3.8 2.9 1.7 1.5 0.8 0.9 0.8 1.4 0.9 0.6 1.5 0.3 1.2 1.4 0.8 1.7 2.9 1.5 1.0 1.2 5.6 0.6 3.1 0.6 1.2 1.5 0.5 1.0 2.1 1.1 0.4 1.2 0.6 1.9 3.9 1.8 1.3 1.7 1.3 2.2 1.5 46.5 1.7 2.2 3.3 0.2 0.7 0.2 3.5 1.7 1.2 0.5 0.5 2.8 1.9 0.3 0.3 2.5 2.1 0.7 0.7 1.8 0.3 0.4 1.6 2.5 1.8 10.3 1.1 1.9 0.4 1.8 1.1 0.3 1.2 1.0 3.0 0.1 1.8 1.5 0.4 0.4 1.1 0.2 1.2 2.4 6.6 6.5 8.7 7.3 6.5 6.6 7.4 6.2 7.5 5.3 7.1 7.4 3.8 9.6 5.1 17.3 1.4 16.4 10.2 19.6 0.0 6.0 6.9 17.8 60.4 7.2 15.2 7.3 4.2 2.3 2.0 1.5 23.5 1.3 245.4 3.8 1.8 3.9 1.8 0.0 6.3 2.6 2.7 8.9 0.5 1.1 8.9 0.6 1.8 16.3 2.6 30.3 5.4 3.9 14.2 4.6 16.3 1045.2 4.4 2.3 80.0 3.7 2.5 11.3 0.0 10.6 5.4 1.9 0.1 8.2 1.1 2.9 10.5 4.9 46.4 2.7 6.6 11.0 11.6 5.1 3.2 0.0 31.7 2.3 2.9 0.9 1.6 8.5 DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "intestine: 216.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 317.3;Paneth cells: 154.2;Proximal enterocytes: 527.9;Undifferentiated cells: 148.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" NA NA 42000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 56: Intestine - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Golgi apparatus" "HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209" "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" 10.0 10.5 6.9 5.4 7.9 4.4 10.9 6.7 9.8 9.5 9.0 74.3 216.0 5.7 1.9 14.6 7.3 2.4 17.2 8.6 9.0 21.9 14.8 4.3 2.4 7.4 7.5 5.1 15.4 9.5 13.3 2.0 7.9 8.0 57.1 22.4 10.3 4.5 16.7 14.4 177.0 6.3 6.6 4.7 11.7 17.0 8.2 2.1 11.9 9.9 3.6 6.8 10.5 7.7 13.9 10.0 3.6 13.8 1.2 2.5 10.6 3.8 2.6 11.9 10.7 22.2 10.1 0.8 1.9 4.0 4.8 13.9 11.5 6.7 10.5 7.1 15.2 3.7 10.1 35.6 5.5 3.0 1.2 2.2 7.3 8.6 6.5 1.9 8.8 11.2 36.1 9.3 5.9 12.5 12.6 5.5 4.5 14.2 0.4 15.2 12.8 22.0 9.9 11.4 10.4 4.9 16.0 12.9 33.3 6.6 19.1 3.6 4.8 1.6 18.2 7.6 10.0 14.1 16.7 4.4 6.5 9.3 5.5 0.1 0.1 0.4 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.0 6.9 7.9 6.7 9.8 8.6 9.0 7.4 7.5 7.9 6.6 8.2 7.7 9.1 0.0 1.5 4.2 3.3 4.2 8.9 2.8 4.0 20.7 14.6 13.3 9.6 2.8 2.4 7.3 129.3 7.9 1.4 317.3 58.7 10.7 22.9 10.2 5.0 6.7 12.1 31.5 8.2 11.4 4.7 3.4 8.6 6.8 0.0 5.3 5.3 12.7 3.5 16.8 9.6 72.2 2.0 1.9 4.2 30.5 4.1 2.6 19.6 2.8 3.6 15.8 1.0 4.0 2.0 7.5 154.2 5.3 9.1 11.7 527.9 43.1 3.8 71.0 0.0 5.9 5.9 27.7 6.5 12.0 6.0 7.0 3.1 9.3 148.5 15.2 DIPK1C "C18orf51, FAM69C" ENSG00000187773 "Divergent protein kinase domain 1C" Q0P6D2 18 74434775-74457944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.6;choroid plexus: 11.3;retina: 16.5" "Cell type enriched" "Detected in single" 27 "Cardiomyocytes: 22.1" "Group enriched" "Detected in some" 18 "glioma: 11.1;melanoma: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SK-MEL-30: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048928 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA048928: AB_2680560" "unprognostic (6.35e-2)" "unprognostic (1.13e-2)" "unprognostic (8.09e-2)" "unprognostic (3.32e-2)" "unprognostic (4.08e-2)" "unprognostic (3.19e-1)" "unprognostic (1.43e-2)" "unprognostic (1.10e-1)" "unprognostic (3.31e-1)" "unprognostic (8.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.10e-2)" "unprognostic (1.91e-4)" "unprognostic (2.16e-1)" "unprognostic (6.73e-2)" "unprognostic (3.23e-2)" "unprognostic (4.40e-3)" 0.3 0.1 19.6 0.0 26.4 0.0 0.3 21.4 25.8 1.6 11.3 1.4 0.0 0.2 0.1 0.1 0.2 0.4 8.4 18.6 20.6 0.1 0.3 0.0 0.0 19.7 24.4 0.0 0.1 0.0 0.3 0.1 19.2 0.4 0.1 16.5 0.3 0.6 1.1 4.2 0.3 0.1 16.5 0.1 1.5 6.8 26.0 0.7 0.0 2.0 0.0 0.1 0.4 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 26.4 21.4 25.8 18.6 20.6 19.7 24.4 19.2 16.5 26.0 28.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DLD "DLDH, E3, GCSL, LAD, OGDC-E3" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107891162-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 357.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 356.2;Distal tubular cells: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Approved Nucleoplasm,Mitochondria NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA044849: AB_2679111" "unprognostic (2.01e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-2)" "unprognostic (9.27e-2)" "unprognostic (5.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (9.43e-2)" "unprognostic (7.35e-2)" "prognostic favorable (7.58e-9)" "unprognostic (4.08e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-3)" "unprognostic (1.18e-1)" 108.7 98.9 22.7 42.1 23.7 54.0 49.0 27.1 29.1 36.3 35.6 109.0 81.8 45.3 21.2 94.1 34.3 48.5 264.1 23.1 29.5 153.3 112.8 39.3 50.1 27.1 27.4 30.0 49.2 136.7 27.8 43.1 26.6 45.7 99.3 35.0 50.2 50.3 295.0 38.9 71.9 67.7 24.9 38.4 80.5 31.3 25.7 43.2 64.2 357.0 67.5 66.1 32.7 23.4 171.4 134.5 74.8 127.9 104.6 91.4 88.4 96.5 80.8 110.6 86.2 159.5 95.5 165.9 159.6 103.0 177.7 110.9 150.2 135.8 166.1 111.1 88.4 116.9 175.6 116.7 80.3 194.7 116.0 104.8 97.6 116.4 63.4 72.3 134.0 137.0 298.5 119.7 121.8 188.1 161.8 138.9 87.4 206.0 98.2 113.1 117.8 225.9 151.8 250.8 92.3 99.9 156.3 262.1 143.9 149.9 100.5 165.8 87.9 120.7 97.3 238.1 149.4 89.3 187.1 114.6 115.0 204.1 130.2 132.7 63.9 136.0 46.9 81.6 49.4 37.8 46.8 46.8 87.2 38.5 47.9 50.5 39.9 68.1 116.9 29.9 49.0 64.2 22.7 23.7 27.1 29.1 23.1 29.5 27.1 27.4 26.6 24.9 25.7 23.4 26.7 28.9 20.7 14.7 26.3 31.4 42.7 124.7 31.3 47.1 24.0 19.2 356.2 51.5 70.5 79.1 22.9 110.2 27.3 56.1 226.9 69.3 10.2 27.6 26.2 32.2 30.6 53.9 23.9 55.9 62.7 36.3 36.7 28.0 26.6 35.3 26.0 86.8 69.2 21.9 25.3 44.1 114.0 41.0 26.5 7.3 23.3 37.5 37.4 15.9 62.2 36.0 38.1 21.1 16.7 42.6 51.4 42.2 30.7 24.3 60.0 178.9 55.5 45.5 26.3 28.4 44.8 55.2 51.5 48.0 32.4 108.4 29.5 73.7 78.7 39.2 DLST "DLTS, KGD2, OGDC-E2" ENSG00000119689 "Dihydrolipoamide S-succinyltransferase" P36957 14 74881891-74903743 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003010 Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA 70000 "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Mitochondria, Cytosol" "HPA003010: AB_1078679" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "unprognostic (2.45e-3)" "unprognostic (6.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (5.83e-2)" "unprognostic (3.03e-1)" "unprognostic (1.37e-1)" "unprognostic (2.12e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.13e-12)" "unprognostic (3.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "unprognostic (4.55e-3)" 64.5 85.5 33.5 32.3 34.7 75.0 59.6 35.8 34.7 62.1 43.8 63.3 58.7 47.5 43.2 62.9 46.1 36.2 129.0 30.8 35.1 100.4 78.4 48.5 36.9 35.8 34.5 45.8 44.8 78.8 35.4 44.8 34.3 41.3 59.3 37.1 46.5 43.5 144.7 64.3 58.3 52.1 33.6 46.1 57.7 29.3 37.3 42.5 42.9 224.2 45.7 58.0 49.7 32.5 79.1 81.1 63.7 45.4 98.1 110.6 97.5 106.3 107.8 106.8 99.0 80.9 88.1 81.0 44.3 118.1 48.1 87.8 109.0 105.6 112.0 61.5 43.3 68.4 66.3 74.8 101.4 49.5 45.4 114.0 90.5 103.8 126.7 95.5 106.1 36.6 53.4 55.6 110.3 112.0 59.0 69.7 55.0 146.6 79.0 73.8 93.8 46.7 125.8 100.8 75.5 64.1 100.6 129.4 71.3 54.2 121.7 70.5 90.8 63.8 83.2 79.5 74.0 38.7 43.7 73.4 93.9 47.9 68.8 3.0 1.3 2.3 2.1 2.0 1.8 1.6 1.9 1.6 2.1 1.0 1.5 2.2 1.3 3.5 1.8 2.8 2.0 1.5 33.5 34.7 35.8 34.7 30.8 35.1 35.8 34.5 34.3 33.6 37.3 32.5 24.2 6.4 4.8 14.0 22.7 26.4 23.5 19.7 21.6 19.1 25.1 20.4 28.5 21.5 10.1 20.2 31.3 41.0 27.7 41.9 56.7 37.8 7.3 10.9 20.4 19.8 14.8 22.5 21.9 25.7 38.8 25.6 30.5 18.9 21.0 19.4 23.2 43.6 32.1 13.5 24.6 31.8 12.2 20.9 19.0 6.2 18.0 18.8 23.2 13.1 27.1 10.0 20.6 18.6 18.5 44.3 28.0 20.7 20.0 28.2 49.8 73.3 8.7 20.8 26.3 18.3 24.0 12.1 15.3 34.2 28.4 79.5 23.1 19.3 40.5 27.7 DMAC1 "C9orf123, MGC4730, TMEM261" ENSG00000137038 "Distal membrane arm assembly complex 1" Q96GE9 9 7796500-7888380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 500.8;Hofbauer cells: 221.7;Proximal tubular cells: 254.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA014585 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 7: Non-specific - Mitochondria" "HPA014585: AB_1845803" "unprognostic (1.48e-2)" "unprognostic (3.74e-2)" "unprognostic (7.23e-3)" "prognostic favorable (4.15e-4)" "unprognostic (2.78e-2)" "unprognostic (2.79e-3)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (3.26e-3)" "unprognostic (3.65e-1)" "prognostic favorable (1.96e-11)" "unprognostic (1.75e-1)" "unprognostic (4.19e-1)" "unprognostic (2.35e-1)" "unprognostic (7.41e-2)" 10.6 11.9 16.8 7.7 17.0 6.2 12.4 17.5 21.0 9.3 9.0 12.6 9.8 10.0 11.8 9.3 11.0 6.3 25.4 16.3 17.8 15.9 10.2 7.2 10.0 15.2 15.0 13.2 9.2 21.8 12.3 8.1 15.6 11.9 9.9 9.0 14.3 11.6 43.1 8.5 9.1 8.1 15.1 10.4 10.7 7.0 16.0 20.6 11.8 29.8 8.9 11.5 8.3 16.9 18.5 21.8 19.7 12.3 15.4 19.1 13.3 11.0 7.7 11.5 10.4 9.9 11.3 27.1 5.6 9.8 15.0 9.8 21.2 18.8 11.6 16.2 24.3 49.3 32.7 31.8 15.6 17.2 6.7 24.1 13.2 9.1 13.9 10.6 11.0 24.3 9.2 5.6 12.2 15.7 25.1 39.7 17.5 15.6 10.5 19.0 11.1 16.4 13.2 17.6 31.5 17.6 12.0 8.0 14.1 13.5 10.5 10.5 14.0 8.8 14.2 11.6 7.7 7.0 12.0 14.5 7.4 14.3 9.0 2.0 10.1 4.5 11.5 12.2 17.4 26.5 15.7 12.3 12.6 22.5 20.5 16.5 1.6 20.8 9.8 13.1 19.9 19.6 16.8 17.0 17.5 21.0 16.3 17.8 15.2 15.0 15.6 15.1 16.0 16.9 42.2 70.5 48.5 0.0 15.7 0.0 0.0 0.0 0.0 0.0 69.5 81.5 0.0 0.0 24.1 101.2 0.0 113.6 13.9 0.0 500.8 94.2 0.0 81.4 64.3 30.0 0.0 0.0 0.0 90.7 96.3 32.8 0.0 58.6 27.8 127.7 0.0 0.0 221.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 25.8 0.0 0.0 0.0 0.0 62.4 0.0 0.0 3.1 0.0 0.0 254.7 70.7 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 55.4 17.3 79.3 0.0 0.0 DMAC2 "ATP5SL, FLJ10241" ENSG00000105341 "Distal membrane arm assembly complex 2" Q9NW81 19 41431318-41440717 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Distal tubular cells: 39.2;Ductal cells: 44.0;Exocrine glandular cells: 40.5;Extravillous trophoblasts: 67.9;Hofbauer cells: 40.4;Proximal tubular cells: 46.3;Syncytiotrophoblasts: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041427 Approved Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA041427: AB_2677473" "unprognostic (1.42e-3)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.20e-1)" "unprognostic (6.88e-3)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.77e-4)" "unprognostic (4.37e-1)" "unprognostic (3.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (2.10e-1)" "prognostic favorable (4.07e-5)" "unprognostic (5.20e-2)" "unprognostic (2.48e-1)" "unprognostic (6.60e-2)" "unprognostic (7.29e-3)" 27.3 33.2 29.3 16.1 29.5 18.2 26.2 30.6 34.7 27.6 26.1 41.1 44.9 31.5 10.4 34.5 27.0 14.1 110.1 29.5 30.7 40.8 36.2 32.6 20.5 31.4 31.4 24.4 35.9 33.2 16.2 18.8 31.0 27.5 17.9 18.7 26.4 20.2 68.4 30.8 42.6 22.3 29.8 26.7 38.2 13.9 31.7 25.7 26.9 80.1 17.2 37.1 26.2 30.5 39.1 134.9 48.4 32.4 33.2 32.9 28.8 31.9 36.9 55.7 49.5 96.7 43.5 40.4 47.8 47.3 30.1 28.6 36.9 59.0 28.4 37.3 47.4 38.1 35.2 70.8 49.5 64.6 36.8 52.5 53.3 44.6 31.3 37.9 66.2 54.7 52.3 39.2 38.0 48.4 59.2 26.4 60.5 55.7 40.3 48.7 38.1 35.8 53.8 53.4 34.6 57.1 51.4 41.9 35.0 38.4 39.2 72.3 50.0 47.7 52.0 29.3 55.7 41.0 41.7 36.6 42.5 46.5 35.0 15.0 28.4 24.2 22.0 25.7 22.9 16.8 16.7 22.2 40.3 19.7 17.7 17.2 9.3 22.9 22.8 26.6 21.0 23.2 29.3 29.5 30.6 34.7 29.5 30.7 31.4 31.4 31.0 29.8 31.7 30.5 25.4 28.9 16.9 0.0 3.1 0.0 0.0 0.0 0.0 0.0 25.7 19.7 0.0 0.0 5.6 12.9 0.0 47.9 9.6 0.0 39.2 44.0 0.0 10.3 17.3 11.6 0.0 0.0 0.0 40.5 67.9 9.3 0.0 14.7 7.6 22.4 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 31.6 0.0 0.0 0.0 0.0 29.2 0.0 0.0 1.4 0.0 0.0 46.3 2.9 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 46.4 6.5 21.0 0.0 0.0 DMTN "DMT, EPB49" ENSG00000158856 "Dematin actin binding protein" Q08495 8 22048995-22082527 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 192.5" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 3.8;memory CD8 T-cell: 1.6;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.5;neutrophil: 1.2;T-reg: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;T-cells: 3.8" "Cell line enhanced" "Detected in many" "A549: 68.9;HEL: 225.9;Hep G2: 63.9;HMC-1: 65.6;OE19: 67.3;RPTEC TERT1: 87.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024290, HPA058487" Uncertain NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA024290: AB_1847601, HPA058487: " "unprognostic (6.74e-2)" "unprognostic (1.51e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (7.92e-5)" "unprognostic (2.88e-1)" "unprognostic (3.85e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-2)" "unprognostic (2.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.97e-1)" "prognostic favorable (3.85e-9)" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "unprognostic (8.07e-2)" 35.7 29.8 104.2 6.1 134.6 136.6 21.8 0.0 192.5 13.5 0.0 33.1 9.2 15.3 14.4 18.9 30.4 13.5 71.5 142.1 36.9 67.5 28.2 20.1 3.4 27.0 14.0 3.4 29.6 54.9 109.6 7.4 27.1 25.0 15.2 23.0 22.9 20.4 66.4 24.3 14.0 14.0 0.0 19.3 23.8 11.7 32.4 3.0 39.1 41.4 3.7 12.9 12.4 90.5 44.1 68.9 0.5 1.4 1.1 0.3 5.4 4.6 4.3 14.5 4.3 29.9 26.7 0.4 43.8 0.8 0.9 14.8 2.1 2.7 6.5 0.4 13.0 225.9 5.3 63.9 1.3 0.1 65.6 0.7 29.3 0.2 0.3 8.5 14.7 2.0 21.7 2.2 0.1 18.9 5.7 0.5 1.8 67.3 6.1 0.0 0.6 3.1 87.2 12.3 15.6 21.8 7.3 0.9 3.2 3.5 11.2 2.2 26.1 0.0 22.0 0.3 24.0 0.1 0.2 0.7 0.3 0.2 15.4 0.0 0.1 0.2 1.7 0.0 1.7 0.0 3.8 1.6 0.1 0.0 1.5 1.5 1.2 0.0 0.0 0.3 3.3 9.3 104.2 134.6 0.0 192.5 142.1 36.9 27.0 14.0 27.1 0.0 32.4 90.5 9.3 3.2 10.7 10.7 1.5 2.3 4.0 3.9 1.2 34.6 9.9 5.7 37.8 0.0 5.1 7.3 12.5 0.1 2.7 15.3 19.6 11.4 12.7 11.2 1.7 10.2 20.5 248.6 45.7 11.4 1.7 2.4 7.7 12.7 0.0 4.1 3.9 15.8 0.5 28.6 29.7 8.7 0.0 1.0 1.6 7.7 0.3 44.5 14.2 5.6 1.3 2.6 0.0 1.5 4.3 18.2 10.0 2.6 1.4 3.7 1.8 29.6 9.3 7.3 0.0 1.4 5.7 1.4 2.4 3.8 5.7 0.1 6.4 0.3 13.3 4.8 DNAJC19 "Pam18, Tim14, TIMM14" ENSG00000205981 "DnaJ heat shock protein family (Hsp40) member C19" Q96DA6 3 180983709-180989774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone Cardiomyopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 471.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037782 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA037782: AB_10672611" "unprognostic (4.52e-2)" "unprognostic (3.55e-3)" "unprognostic (3.08e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-1)" "unprognostic (5.54e-2)" "unprognostic (1.39e-1)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "prognostic favorable (8.53e-5)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.14e-2)" "unprognostic (1.75e-1)" "unprognostic (4.66e-1)" "unprognostic (3.33e-1)" "unprognostic (4.20e-3)" 22.7 44.1 26.1 11.1 27.1 10.8 26.4 27.2 39.7 19.4 28.8 27.5 21.4 18.9 33.0 22.9 21.3 11.8 73.4 27.2 28.0 50.2 48.9 14.7 16.3 26.4 29.3 26.5 27.9 34.7 30.9 14.2 26.3 22.6 17.7 27.2 28.1 18.2 65.8 15.0 18.1 11.8 27.6 18.5 26.2 11.6 26.8 20.7 25.6 77.8 13.4 23.5 18.4 28.1 53.9 14.0 38.8 29.6 45.6 27.0 35.4 30.2 18.2 29.1 25.5 49.0 26.2 23.0 63.9 25.5 70.9 26.8 37.8 36.5 35.9 36.5 49.1 27.0 24.5 48.3 48.9 64.9 27.5 25.9 29.8 24.4 43.0 37.9 34.0 55.2 42.8 35.8 23.0 44.2 48.5 54.6 51.2 75.9 44.8 31.4 26.9 69.6 43.3 24.8 38.7 20.6 30.8 75.8 82.3 44.0 85.2 45.2 16.8 18.5 27.1 26.3 54.4 47.7 60.7 80.1 19.0 49.9 22.9 33.6 20.4 31.5 33.3 22.3 39.8 34.7 38.5 34.7 28.6 29.8 39.8 40.6 4.4 26.8 27.3 36.4 35.0 30.8 26.1 27.1 27.2 39.7 27.2 28.0 26.4 29.3 26.3 27.6 26.8 28.1 68.3 38.5 52.5 11.1 66.3 56.6 68.6 105.4 56.9 31.7 138.6 183.0 151.7 120.1 70.1 77.3 14.6 116.6 67.4 57.9 471.6 83.9 9.1 57.4 50.4 61.4 45.2 48.8 18.7 109.3 111.2 71.7 30.1 42.7 110.7 79.7 68.6 167.0 68.0 48.8 20.5 90.7 91.6 35.5 59.8 13.2 85.1 42.8 74.7 9.4 58.6 91.4 74.2 13.0 21.4 79.9 66.1 72.6 47.7 91.5 101.0 216.8 58.7 67.6 85.5 80.3 108.8 82.1 56.3 73.9 60.1 68.7 68.4 121.4 86.7 69.2 DNAJC28 "C21orf55, C21orf78" ENSG00000177692 "DnaJ heat shock protein family (Hsp40) member C28" Q9NX36 21 33485530-33491716 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.0;Early spermatids: 33.3;Proximal tubular cells: 10.4;Spermatocytes: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018003, HPA030076" Approved NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA018003: AB_1845695, HPA030076: AB_10602218" "unprognostic (9.63e-3)" "unprognostic (4.44e-1)" "unprognostic (5.66e-3)" "unprognostic (2.05e-1)" "unprognostic (4.00e-2)" "unprognostic (4.92e-3)" "unprognostic (2.89e-2)" "unprognostic (6.61e-3)" "unprognostic (1.45e-1)" "unprognostic (7.23e-4)" "unprognostic (1.20e-3)" "unprognostic (1.04e-1)" "unprognostic (3.14e-9)" "unprognostic (1.84e-1)" "unprognostic (1.71e-1)" "unprognostic (4.53e-2)" "unprognostic (1.24e-2)" 0.6 2.2 0.8 0.1 0.8 0.4 0.7 0.9 1.2 0.5 0.7 1.1 0.3 0.5 1.2 1.1 0.3 0.5 2.9 0.8 0.7 2.6 2.6 0.6 0.2 0.8 0.7 0.4 1.3 1.4 1.5 0.5 0.8 0.8 0.7 1.7 1.4 0.6 2.8 0.6 1.1 0.3 0.5 1.2 1.5 7.0 0.8 0.1 2.5 2.0 0.1 0.7 0.6 0.9 0.3 0.1 1.2 0.4 3.1 0.8 0.3 0.6 0.6 1.2 0.5 0.1 0.5 0.3 0.1 0.0 0.6 0.1 0.1 0.1 0.3 0.1 1.3 0.7 0.2 0.8 0.7 0.0 1.2 0.6 0.6 0.6 0.1 1.0 0.7 0.6 0.4 0.1 0.4 0.4 0.1 0.3 0.6 0.4 0.0 0.3 1.3 0.1 0.6 0.1 0.9 0.6 0.1 0.0 0.3 0.4 1.1 0.2 0.2 0.5 0.2 0.1 0.1 0.5 0.5 0.1 1.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.8 0.8 0.9 1.2 0.8 0.7 0.8 0.7 0.8 0.5 0.8 0.9 1.3 0.0 2.2 0.3 0.7 0.4 0.3 1.1 1.8 1.7 1.2 0.9 14.0 1.5 0.5 3.7 0.0 1.3 0.9 1.3 3.9 2.2 33.3 0.7 0.8 1.4 1.2 4.0 2.5 1.3 0.4 1.1 1.1 0.9 3.8 0.8 1.4 4.7 1.0 1.7 2.3 1.1 0.0 2.4 0.3 7.6 0.6 0.9 0.0 1.9 1.3 0.9 0.0 1.0 1.2 1.7 1.2 1.2 2.0 0.6 1.8 10.4 2.4 2.2 0.0 1.1 1.2 13.4 2.0 0.6 0.0 2.3 0.8 3.0 0.6 0.2 DNAJC30 WBSCR18 ENSG00000176410 "DnaJ heat shock protein family (Hsp40) member C30" Q96LL9 7 73680918-73683453 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" Chaperone "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 120.1;Late spermatids: 230.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017318 Supported NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA017318: AB_1858788" "unprognostic (1.86e-2)" "unprognostic (1.85e-1)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (5.37e-2)" "unprognostic (1.50e-1)" "unprognostic (2.66e-2)" "unprognostic (4.53e-1)" "unprognostic (3.93e-2)" "unprognostic (2.85e-3)" "unprognostic (4.60e-2)" "prognostic favorable (4.91e-8)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (2.51e-1)" "unprognostic (1.20e-2)" 6.4 14.7 7.2 3.1 7.9 2.9 6.3 7.1 8.3 5.5 5.5 6.0 3.8 7.1 4.6 5.4 6.4 2.0 11.3 7.9 7.1 9.7 11.9 3.9 3.5 7.0 6.9 6.2 7.9 6.6 10.5 2.7 7.2 6.6 3.2 3.8 6.1 4.7 9.3 5.0 5.2 2.9 5.1 6.0 6.3 12.5 6.9 3.7 8.7 4.8 2.9 6.2 4.4 7.2 6.5 6.3 4.6 9.2 7.0 4.9 4.8 10.0 7.3 7.6 7.4 6.1 6.6 5.7 2.5 8.0 11.2 9.0 4.1 5.6 4.3 6.7 8.4 3.3 6.0 6.5 7.2 5.6 4.5 5.5 4.6 6.9 5.9 5.3 6.6 7.3 6.8 5.0 7.5 13.0 9.1 11.3 3.9 6.0 10.6 6.2 3.6 14.1 9.9 7.5 12.3 6.6 10.2 17.7 7.9 4.6 16.1 3.7 6.5 8.0 5.8 8.4 7.2 5.3 3.9 5.4 6.4 3.8 10.0 5.4 6.2 3.9 6.3 5.7 7.7 7.4 7.7 7.6 6.0 9.8 9.1 7.8 0.8 6.0 4.4 6.3 5.6 5.2 7.2 7.9 7.1 8.3 7.9 7.1 7.0 6.9 7.2 5.1 6.9 7.2 10.0 19.2 6.2 2.3 14.7 5.9 16.6 19.9 12.5 34.9 13.9 11.9 19.7 14.3 15.8 18.4 14.6 43.6 18.6 7.2 56.7 30.2 120.1 15.9 13.3 10.6 17.4 6.9 5.6 28.0 16.2 13.9 16.3 11.3 12.7 20.8 15.0 25.3 22.3 20.2 6.1 12.8 12.2 13.2 5.3 230.1 24.5 9.3 14.2 2.8 26.9 24.6 32.0 2.5 8.9 19.2 8.4 18.4 9.4 13.3 15.4 81.8 10.0 29.5 19.7 12.6 12.4 69.6 16.5 16.9 8.2 36.0 11.2 56.0 17.1 12.6 DNAJC4 "HSPF2, MCG18" ENSG00000110011 "DnaJ heat shock protein family (Hsp40) member C4" Q9NNZ3 11 64230278-64234286 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 240.9" "Cell type enriched" "Detected in all" 5 "Late spermatids: 3342.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011947 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA011947: AB_1847803" "unprognostic (8.99e-3)" "unprognostic (2.28e-2)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.95e-2)" "unprognostic (1.15e-1)" "unprognostic (5.20e-2)" "unprognostic (8.99e-2)" "unprognostic (1.56e-2)" "unprognostic (7.69e-2)" "unprognostic (5.44e-3)" "unprognostic (1.73e-3)" "unprognostic (1.07e-1)" "prognostic favorable (6.21e-4)" "unprognostic (2.47e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (2.69e-1)" 38.4 80.5 48.3 25.0 48.9 43.2 38.8 47.9 51.0 52.0 52.3 53.2 39.0 37.8 35.6 44.1 40.2 23.9 94.3 44.5 48.5 71.1 71.8 38.5 35.0 50.7 48.7 61.4 98.5 33.3 54.6 16.4 50.8 58.5 22.8 11.3 59.9 23.2 64.2 55.1 53.7 16.1 47.6 70.4 62.3 240.9 52.8 29.0 57.2 49.2 33.3 43.0 40.4 46.3 12.4 11.6 26.9 39.9 32.0 56.0 18.8 17.9 30.2 10.9 15.0 11.6 17.6 14.9 57.6 32.1 6.4 9.7 13.5 16.2 6.3 31.6 15.9 18.5 12.2 31.8 39.0 13.9 42.3 58.4 42.9 17.3 20.2 51.5 26.1 16.4 12.7 76.2 7.1 30.4 5.6 33.2 7.8 29.1 22.3 38.7 7.1 101.1 45.4 8.2 23.4 37.9 18.0 20.2 68.8 25.6 48.8 24.6 24.3 12.6 12.6 19.4 10.2 74.8 32.8 18.6 11.1 17.3 36.8 48.2 57.6 42.7 21.9 52.2 27.7 47.6 21.8 25.6 80.4 49.1 30.9 24.8 31.2 41.6 42.7 129.8 22.4 36.4 48.3 48.9 47.9 51.0 44.5 48.5 50.7 48.7 50.8 47.6 52.8 46.3 29.8 12.8 30.5 11.4 69.5 43.7 58.2 54.5 95.0 21.1 93.8 119.9 22.3 34.3 37.8 27.6 8.4 80.1 58.1 47.6 160.4 37.6 667.3 22.1 27.3 35.1 81.3 28.2 5.0 38.5 60.2 34.4 45.9 24.9 46.3 41.6 43.2 32.4 53.0 25.2 6.9 74.1 69.2 69.5 63.8 3342.9 62.7 66.0 48.0 4.7 112.4 35.0 55.6 3.0 5.5 28.7 55.6 46.6 96.3 43.4 115.0 101.7 15.1 14.5 19.7 29.0 30.3 28.4 28.8 60.1 51.1 54.5 46.6 61.9 68.9 64.9 DNAJC5G "CSP-gamma, FLJ40417" ENSG00000163793 "DnaJ heat shock protein family (Hsp40) member C5 gamma" Q8N7S2 2 27275433-27281499 "Predicted membrane proteins" Chaperone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 14 "epididymis: 46.9;testis: 22.8" "Group enriched" "Detected in some" 4 "Early spermatids: 69.1;Late spermatids: 83.6;Spermatocytes: 105.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HAP1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA041445 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041445: AB_2677485" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (2.26e-1)" "unprognostic (3.99e-1)" "unprognostic (2.77e-1)" "unprognostic (1.56e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-1)" "unprognostic (4.06e-1)" "unprognostic (1.75e-4)" "unprognostic (2.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" "unprognostic (7.67e-2)" "unprognostic (1.97e-2)" 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.0 2.5 0.4 0.0 0.1 0.0 0.4 46.9 0.0 0.4 0.0 1.3 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.8 0.1 0.0 2.5 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.1 0.0 0.0 0.3 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 83.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 105.1 19.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 DNASE1L1 "DNAS1L1, DNASEX, DNL1L, XIB" ENSG00000013563 "Deoxyribonuclease 1 like 1" P49184 X 154401236-154412112 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 147.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072635 Approved "Intracellular and membrane" NA NA 96000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA072635: AB_2686542" "unprognostic (5.27e-2)" "unprognostic (1.95e-1)" "unprognostic (4.57e-3)" "unprognostic (2.97e-1)" "unprognostic (1.27e-2)" "unprognostic (1.59e-3)" "unprognostic (3.82e-2)" "unprognostic (3.08e-2)" "unprognostic (2.88e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (4.98e-1)" "prognostic favorable (2.19e-4)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "unprognostic (6.75e-2)" 18.7 26.6 12.6 13.0 12.1 24.1 17.8 11.7 14.1 15.8 26.6 15.2 15.2 15.8 22.5 21.6 14.0 13.0 43.2 13.5 14.3 20.9 18.8 22.0 16.4 12.2 13.4 13.7 12.8 22.7 20.1 16.1 12.6 15.1 12.3 3.9 22.0 11.3 147.0 11.3 19.3 11.3 13.0 28.5 18.1 7.7 13.6 8.9 24.1 94.8 13.2 13.5 16.9 11.9 19.7 19.6 6.3 12.2 56.6 74.5 7.7 54.5 85.3 17.6 34.6 5.7 28.0 32.9 68.2 103.0 67.4 9.6 7.6 31.0 12.8 9.9 13.0 4.8 20.6 7.1 38.8 8.6 33.4 55.6 35.7 39.6 40.0 47.9 76.4 5.3 6.5 34.0 61.1 33.0 3.6 4.2 5.0 35.5 22.1 7.3 28.5 52.9 31.0 9.7 20.2 12.0 17.1 29.9 22.5 13.9 11.9 7.8 112.9 17.7 20.3 25.6 10.9 64.2 15.4 34.4 26.6 14.4 22.4 13.0 12.0 17.1 3.5 21.6 4.0 6.2 3.3 3.1 14.5 4.1 2.4 2.2 7.0 4.6 20.9 8.3 4.9 6.4 12.6 12.1 11.7 14.1 13.5 14.3 12.2 13.4 12.6 13.0 13.6 11.9 20.1 6.4 6.5 3.3 8.0 1.3 7.1 11.1 9.6 1.8 5.1 3.8 2.0 5.7 5.4 5.5 0.0 5.3 6.7 15.5 9.8 6.1 0.1 5.8 5.7 17.7 6.1 6.5 3.2 10.2 23.3 5.2 11.7 7.5 13.3 4.9 23.2 8.6 29.1 0.0 2.2 10.4 6.1 36.6 11.7 1.2 3.4 25.4 16.0 4.7 22.9 12.8 7.2 0.0 0.5 13.5 18.1 2.6 6.8 5.9 27.0 9.6 7.0 1.4 0.0 16.7 3.3 0.4 0.4 10.4 1.7 8.9 6.0 3.2 10.9 10.9 DPF3 "BAF45c, cer-d4, Cerd4, FLJ14079" ENSG00000205683 "Double PHD fingers 3" Q92784 14 72619296-72894116 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;retina: 18.0;skeletal muscle: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 108.4;Early spermatids: 58.5;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 115.7;Rod photoreceptor cells: 85.5" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;BJ hTERT+ SV40 Large T+: 12.2;HEL: 31.5;Karpas-707: 12.4" "Region enhanced" "Detected in all" "cerebellum: 49.5" "Low region specificity" "Detected in all" "HPA066790, HPA070601" Enhanced Enhanced Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA066790: AB_2685724, HPA070601: AB_2686284" "unprognostic (2.38e-2)" "unprognostic (2.96e-1)" "unprognostic (3.25e-1)" "unprognostic (1.56e-2)" "unprognostic (1.55e-1)" "unprognostic (9.98e-2)" "unprognostic (4.80e-2)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (3.54e-2)" "unprognostic (9.71e-3)" "unprognostic (1.02e-1)" "unprognostic (2.02e-1)" "unprognostic (3.85e-3)" "unprognostic (4.08e-2)" "unprognostic (4.80e-2)" "unprognostic (1.96e-1)" 0.3 1.4 2.8 0.5 6.7 2.6 0.4 35.5 5.1 0.4 0.0 2.0 0.2 0.2 0.0 0.6 0.3 0.3 14.2 10.2 3.8 1.4 3.0 0.2 0.8 12.0 5.9 13.7 0.3 5.1 0.6 0.3 12.6 0.1 1.5 18.0 0.4 0.2 26.5 0.5 1.3 0.5 4.4 1.0 0.5 3.5 5.7 0.3 0.4 9.1 1.0 0.2 0.2 7.7 2.1 0.0 1.6 0.1 0.2 2.9 17.7 5.4 5.1 12.2 4.7 0.1 0.2 0.2 0.3 1.7 0.2 0.1 1.7 0.8 7.4 0.3 0.6 31.5 0.2 0.0 0.5 0.2 0.5 0.7 0.3 2.8 2.0 2.0 4.0 3.4 2.8 12.4 3.9 0.1 2.7 0.3 0.0 0.0 1.8 6.9 0.8 0.4 2.1 0.0 1.2 0.7 0.0 0.1 0.0 0.5 0.0 0.0 8.7 6.0 0.0 2.2 0.6 4.3 1.2 0.4 0.5 1.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 6.7 35.5 5.1 10.2 3.8 12.0 5.9 12.6 4.4 5.7 7.7 0.8 0.0 0.0 104.5 6.0 0.6 0.1 0.0 0.0 10.5 1.1 0.9 38.4 1.5 0.0 0.0 108.4 2.6 2.6 7.5 1.9 0.1 58.5 0.1 0.8 2.9 0.0 8.6 17.7 0.4 1.3 2.8 0.0 0.1 4.5 43.2 1.1 4.4 0.4 6.7 21.7 3.4 0.0 0.8 0.7 34.3 0.3 1.7 0.0 8.4 0.1 8.6 2.1 123.1 115.7 0.7 5.1 4.9 2.6 0.1 2.7 10.7 0.0 85.5 0.0 2.6 3.5 4.5 1.2 0.3 0.3 0.1 3.8 14.5 7.4 0.0 DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.6" "Group enriched" "Detected in many" 4 "Early spermatids: 329.9;Excitatory neurons: 124.1;Inhibitory neurons: 137.2;Late spermatids: 363.0;Oligodendrocyte precursor cells: 124.1;Spermatocytes: 143.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 9.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Mitochondria Nucleoplasm "HPA071264: AB_2686375, HPA078305: " "unprognostic (1.97e-1)" "unprognostic (4.08e-1)" "unprognostic (4.46e-3)" "unprognostic (2.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.17e-4)" "unprognostic (2.28e-2)" "unprognostic (2.14e-3)" "unprognostic (1.53e-1)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (4.22e-3)" "unprognostic (5.88e-2)" "unprognostic (8.90e-3)" "unprognostic (1.79e-1)" 6.7 5.3 4.0 0.5 3.9 3.0 4.7 7.0 6.9 11.4 6.6 5.2 0.6 7.8 4.1 1.4 6.4 2.8 19.2 3.0 4.3 12.7 0.2 1.3 0.9 2.4 3.0 11.0 2.7 9.0 10.5 1.2 1.5 9.3 1.3 14.4 1.6 4.7 0.5 1.6 1.7 3.5 0.8 1.7 2.9 65.6 3.3 0.7 13.1 0.6 0.6 6.3 5.1 4.2 1.0 2.6 2.2 5.4 0.6 0.0 0.2 1.8 1.8 2.4 3.1 0.4 0.8 2.8 1.8 0.7 2.9 0.4 2.7 0.3 3.6 1.5 1.7 4.6 1.4 1.7 0.5 3.4 1.4 1.5 0.1 1.1 0.0 6.1 0.8 2.2 1.9 2.9 3.9 1.7 0.2 1.4 2.1 0.4 2.4 0.0 1.8 0.0 4.6 0.5 7.0 0.7 0.6 0.2 1.0 0.9 1.9 0.9 0.5 3.2 4.2 0.5 4.6 7.5 9.3 0.0 3.4 1.6 3.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 4.0 3.9 7.0 6.9 3.0 4.3 2.4 3.0 1.5 0.8 3.3 4.2 6.7 3.2 0.0 23.2 0.2 0.5 2.9 0.1 2.2 49.6 1.9 1.8 32.3 1.5 3.8 12.9 14.6 2.0 0.3 0.1 5.9 0.4 329.9 5.6 7.1 1.7 0.0 7.2 124.1 0.0 1.3 2.2 0.5 2.1 2.5 1.2 1.4 0.1 0.3 3.3 137.2 0.1 6.1 0.0 0.4 363.0 7.2 0.4 7.2 11.2 0.1 9.2 0.0 124.1 5.0 0.2 0.0 8.6 0.5 2.9 0.0 6.4 11.6 6.7 26.3 3.8 19.9 143.3 4.9 0.2 0.4 1.4 0.8 3.6 0.1 1.1 DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 228.8" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 166.5" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075379 Enhanced NA NA 27000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" 0.2 0.0 0.0 0.1 0.0 0.2 9.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 228.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 2.6 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 14.1 0.3 0.0 2.2 0.9 0.1 0.4 29.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.4 0.0 0.0 3.6 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.5 166.5 0.4 0.6 0.0 0.0 0.3 DTWD2 FLJ33977 ENSG00000169570 "DTW domain containing 2" Q8NBA8 5 118836074-118988547 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.4;Inhibitory neurons: 61.8;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053173, HPA054864" Approved Approved "Nuclear bodies" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear bodies" "HPA053173: AB_2682068, HPA054864: AB_2682629" "unprognostic (1.66e-1)" "unprognostic (1.60e-1)" "prognostic favorable (3.16e-4)" "unprognostic (4.80e-2)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.11e-1)" "unprognostic (2.77e-3)" "unprognostic (5.15e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.09e-5)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (5.93e-3)" "unprognostic (1.59e-1)" 3.1 3.3 1.3 2.3 1.3 1.2 3.6 2.3 1.8 5.1 2.2 3.3 3.2 2.6 2.3 4.2 2.3 3.2 6.5 1.2 0.8 6.5 4.5 2.4 2.3 1.1 1.4 1.7 3.0 4.7 0.8 1.8 1.2 3.4 3.3 3.4 3.2 2.7 10.5 3.3 2.7 3.2 1.0 3.0 2.7 2.4 1.3 2.0 9.1 6.3 2.3 2.9 1.3 1.4 4.3 2.6 3.6 5.3 2.0 1.0 3.6 3.9 2.7 5.5 6.3 1.8 3.2 3.6 6.9 3.4 2.6 4.8 6.0 4.4 6.9 1.2 4.2 4.9 4.3 2.9 1.7 5.9 6.1 1.5 7.4 2.4 2.4 3.2 1.8 6.4 3.8 5.5 3.7 4.2 4.9 3.6 3.8 3.1 1.4 2.0 3.3 1.9 7.0 6.2 1.8 3.3 3.9 4.2 5.4 2.9 9.7 3.9 2.2 6.9 5.1 2.3 5.7 3.8 6.6 2.8 4.0 3.5 3.4 0.9 0.3 0.1 0.2 0.3 0.3 0.4 0.3 0.3 0.3 0.6 0.4 0.4 0.6 0.5 0.3 0.5 0.1 0.4 1.3 1.3 2.3 1.8 1.2 0.8 1.1 1.4 1.2 1.0 1.3 1.4 2.7 9.6 3.6 33.6 5.7 2.8 2.7 3.9 8.6 12.0 5.4 2.8 11.7 8.6 4.7 7.3 16.7 2.7 3.7 4.0 9.8 2.9 12.8 4.2 1.9 2.0 4.2 12.6 70.4 8.3 1.1 3.0 9.7 3.6 0.0 4.5 1.8 5.6 3.9 20.2 61.8 2.0 4.1 2.6 2.5 20.3 2.5 4.5 7.2 21.5 4.6 7.3 4.1 49.3 43.9 1.9 5.2 2.2 8.0 2.1 3.7 12.1 3.1 9.1 0.0 4.5 2.8 12.7 17.4 10.0 3.7 0.7 2.8 7.3 3.4 3.4 DUSP26 "DUSP24, MGC1136, NEAP" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591330-33600023 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 421.3;tongue: 204.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 76.8;Cardiomyocytes: 59.4;Cone photoreceptor cells: 41.7;Enteroendocrine cells: 25.7;Horizontal cells: 25.2;Rod photoreceptor cells: 75.2" "Cancer enhanced" "Detected in some" "glioma: 6.7;pancreatic cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 0.7 27.4 44.2 1.2 45.2 0.2 0.4 47.4 49.6 1.2 18.4 2.8 3.5 1.3 5.6 5.0 3.6 1.2 70.8 45.0 53.0 1.5 0.2 3.3 0.4 39.8 42.1 33.2 3.0 2.0 61.4 0.0 55.2 4.2 1.1 34.1 4.6 0.8 421.3 0.3 2.6 2.7 38.3 0.7 3.9 3.6 44.4 0.8 0.9 204.4 0.8 1.2 1.7 41.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 97.7 23.1 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.1 3.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.2 45.2 47.4 49.6 45.0 53.0 39.8 42.1 55.2 38.3 44.4 41.1 0.0 0.0 0.0 1.3 0.9 0.0 0.2 0.0 0.6 76.8 0.0 0.3 59.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 21.5 0.4 7.8 0.4 0.1 0.8 25.7 0.0 11.3 0.4 0.0 3.5 0.5 0.1 0.0 1.0 0.4 0.0 0.0 25.2 14.7 0.5 0.0 0.0 0.0 5.2 0.0 0.1 1.8 2.8 0.0 22.8 0.0 12.1 12.0 1.1 0.0 6.0 5.3 0.3 0.0 2.5 0.0 75.2 0.0 10.8 5.2 0.2 0.2 0.0 0.0 0.0 0.6 0.7 0.1 0.1 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240565256 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 39.7;Spermatocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 8.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 8.9" "Cell line enhanced" "Detected in many" "U-266/70: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favorable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.5 2.4 1.6 1.3 1.7 5.4 1.7 3.0 1.8 2.2 0.5 2.5 1.1 2.1 1.7 3.1 2.6 0.8 3.4 1.3 1.7 3.2 3.2 2.2 1.9 1.7 1.2 2.2 3.0 0.9 3.9 0.6 1.4 3.5 1.0 1.2 2.8 0.8 9.8 2.0 3.6 0.6 1.1 4.7 2.7 6.2 1.5 1.1 3.5 4.0 1.5 2.3 2.2 2.0 1.0 0.8 1.1 1.4 0.7 0.4 1.3 1.0 0.6 0.8 0.5 0.5 2.4 1.7 0.6 0.6 1.3 3.1 0.9 0.3 0.7 2.2 4.0 2.1 2.2 1.3 0.5 1.6 3.7 1.0 0.9 0.6 0.6 1.6 0.4 2.3 1.6 1.9 0.7 1.1 1.7 2.5 0.9 1.4 0.9 2.3 2.4 2.1 0.6 1.6 2.8 1.5 0.9 1.1 1.3 0.7 1.2 2.2 1.0 1.9 1.6 1.3 1.0 8.2 2.1 2.8 1.2 1.0 1.5 8.9 1.1 0.5 1.2 0.7 1.4 1.0 1.2 1.3 0.6 1.8 1.4 1.2 1.9 1.5 0.7 1.9 0.9 0.9 1.6 1.7 3.0 1.8 1.3 1.7 1.7 1.2 1.4 1.1 1.5 2.0 5.7 0.0 4.5 1.3 11.4 3.7 7.7 4.7 6.2 6.7 12.3 10.0 13.8 10.0 3.8 12.9 4.2 7.8 18.4 11.0 15.6 5.1 35.2 11.2 5.5 4.1 8.4 8.8 3.8 5.8 4.8 4.3 14.8 10.2 7.0 6.2 3.3 8.6 11.5 8.4 4.9 9.8 6.1 10.0 6.1 39.7 3.1 13.6 7.2 1.9 10.5 9.9 23.7 2.5 3.6 4.4 10.4 1.5 16.8 8.0 15.7 15.6 11.7 6.8 6.6 4.1 7.2 45.8 18.7 10.7 5.4 7.0 14.9 7.6 11.2 8.7 ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239402-2252300 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 301.3;Hepatocytes: 246.5;Proximal tubular cells: 272.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 7300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041746: AB_10960693, HPA043227: AB_10960273" "unprognostic (4.99e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.75e-1)" "unprognostic (2.92e-3)" "unprognostic (8.90e-2)" "unprognostic (2.85e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-2)" "unprognostic (2.66e-2)" "prognostic favorable (8.99e-8)" "unprognostic (2.61e-2)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.08e-3)" 51.5 57.3 35.9 12.7 39.2 19.6 52.0 38.6 45.9 46.2 61.6 74.0 59.9 44.9 10.6 57.0 50.7 11.3 189.7 32.1 38.0 123.2 235.7 37.2 13.8 39.1 37.8 38.6 74.7 43.8 50.4 14.6 35.0 56.6 15.0 12.8 78.7 24.2 220.6 49.7 58.8 9.3 37.3 35.3 69.5 18.2 42.0 13.4 105.0 87.8 9.5 50.3 43.6 36.5 29.5 68.0 25.7 107.4 9.6 13.6 96.6 29.5 19.1 23.1 33.7 120.0 88.0 42.3 71.2 17.7 16.9 71.6 29.6 27.5 3.2 74.2 157.1 12.9 61.7 151.7 87.3 38.6 6.0 25.2 63.1 18.9 41.7 16.4 23.6 1.1 71.7 87.1 8.0 119.1 4.0 57.8 60.1 46.8 68.8 134.3 27.7 207.1 45.5 32.5 88.8 56.2 70.0 131.4 92.7 12.6 84.7 67.7 19.6 18.4 68.0 19.9 33.0 95.8 61.0 72.2 23.9 35.4 26.2 1.7 3.6 1.6 1.9 3.8 3.1 4.4 2.8 1.6 3.0 4.9 3.4 2.9 2.0 3.6 2.5 3.6 4.0 0.8 35.9 39.2 38.6 45.9 32.1 38.0 39.1 37.8 35.0 37.3 42.0 36.5 47.1 3.2 28.2 13.4 28.0 21.3 115.6 11.3 21.1 53.2 77.2 95.1 92.3 94.4 15.0 77.3 43.8 179.6 20.5 151.7 301.3 35.1 10.9 128.2 54.8 28.2 45.5 61.7 4.2 36.9 80.7 33.1 33.1 122.8 5.7 62.2 34.2 246.5 47.9 21.9 6.7 105.9 20.3 31.0 23.8 5.3 24.5 29.8 39.2 4.7 17.5 89.9 5.2 13.0 10.0 33.2 91.1 24.0 36.8 72.8 176.1 272.3 14.6 77.6 0.0 73.4 42.7 6.3 19.6 32.9 22.3 109.9 21.7 50.2 104.7 110.5 ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 422.7" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 293.6;Distal tubular cells: 428.4;Proximal tubular cells: 577.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" 53.6 123.6 43.9 21.0 47.7 21.5 65.0 46.5 63.7 60.0 50.5 53.3 64.0 44.9 102.1 26.7 49.2 40.1 150.9 42.4 47.8 236.0 422.7 28.6 20.0 45.0 45.6 71.4 159.8 53.2 52.6 37.7 44.2 45.2 55.4 31.8 29.9 36.3 198.4 22.7 59.6 35.5 45.3 30.1 103.5 30.9 49.0 33.5 37.0 236.4 21.8 31.6 26.8 45.5 82.8 45.1 72.8 161.0 89.7 131.4 8.8 114.0 116.7 122.1 107.7 34.0 12.4 3.6 139.6 126.0 111.0 41.6 83.6 67.4 179.5 30.4 95.8 44.0 59.7 186.8 51.3 40.4 20.7 90.6 40.6 106.2 58.4 166.0 262.9 136.2 146.2 31.1 118.6 33.4 113.9 100.7 49.5 8.1 158.7 108.8 90.8 1.5 67.2 16.8 1.8 33.7 6.8 48.2 107.6 131.0 109.8 18.9 268.6 92.4 49.8 82.7 69.8 46.8 88.7 8.4 47.9 34.7 73.0 19.2 36.4 17.4 41.5 28.4 57.1 45.8 48.8 58.3 58.9 51.9 59.8 59.2 1.2 66.0 43.3 45.3 57.9 41.1 43.9 47.7 46.5 63.7 42.4 47.8 45.0 45.6 44.2 45.3 49.0 45.5 61.0 28.9 25.2 17.0 24.4 18.2 48.6 50.3 22.2 14.3 33.3 41.0 165.8 78.6 40.1 36.8 12.5 293.6 29.3 32.0 428.4 53.2 63.1 60.8 43.1 48.0 52.1 77.6 10.7 175.5 29.0 55.2 34.7 57.0 23.4 68.6 53.9 162.2 64.3 18.5 11.9 41.6 20.3 22.0 19.2 50.6 63.3 23.5 35.6 14.0 34.7 77.7 21.6 8.5 18.2 80.4 37.5 50.8 28.3 24.7 120.6 577.0 83.6 46.4 26.3 46.8 33.9 46.5 35.6 24.9 12.8 101.9 41.2 224.0 60.8 22.3 EDARADD ENSG00000186197 "EDAR associated death domain" Q8WWZ3 1 236348257-236502915 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 8.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.7;granulocytes: 22.7;Syncytiotrophoblasts: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 49.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 15.9;HDLM-2: 13.2;HMC-1: 52.7;RT4: 45.3;T-47d: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018836 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA018836: AB_1847984" "unprognostic (3.74e-1)" "unprognostic (3.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.12e-2)" "unprognostic (2.06e-3)" "unprognostic (3.12e-3)" "unprognostic (9.94e-2)" "unprognostic (2.96e-2)" "unprognostic (2.62e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (2.57e-2)" "unprognostic (5.72e-2)" "unprognostic (3.00e-1)" "unprognostic (2.47e-1)" "unprognostic (1.90e-2)" "unprognostic (9.62e-3)" 0.4 0.1 0.2 0.4 0.1 0.4 4.8 0.1 0.1 0.7 0.0 0.3 0.4 0.4 5.2 3.3 1.2 0.8 0.9 0.1 0.1 1.1 0.3 0.7 1.2 0.2 0.2 0.4 3.8 0.1 0.1 4.9 0.1 3.6 0.3 0.0 1.4 6.1 0.0 5.8 0.3 0.1 0.1 1.2 6.3 3.4 0.2 2.3 6.4 0.0 2.6 8.7 1.0 0.1 0.0 3.8 0.3 0.0 0.0 0.0 15.9 0.0 0.0 1.3 0.8 1.0 0.0 0.0 0.0 0.2 4.3 8.8 6.5 9.6 1.2 13.2 7.6 0.1 0.1 1.4 0.0 0.4 52.7 0.0 2.7 0.9 0.8 0.0 0.0 1.8 0.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 3.4 0.1 0.0 0.0 45.3 0.4 0.3 0.0 1.2 0.2 0.3 12.6 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 49.5 0.3 0.1 3.1 0.4 4.1 0.1 4.7 6.1 0.5 0.2 0.4 3.2 0.3 5.3 0.2 0.1 5.1 2.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.0 1.3 0.0 0.4 6.9 7.3 16.3 13.1 0.0 7.1 7.4 4.1 5.7 8.4 0.0 0.0 26.7 3.0 0.1 3.9 1.7 10.6 0.2 1.2 1.2 0.0 2.5 0.5 0.9 14.2 1.1 5.1 0.4 22.7 2.8 5.0 0.5 3.4 0.0 0.6 0.1 8.2 1.5 8.9 9.3 0.3 0.6 12.4 1.0 3.7 0.6 0.0 1.0 0.4 0.6 0.0 0.4 1.8 4.2 0.1 0.4 3.2 0.1 0.0 1.4 6.1 13.4 3.7 6.5 5.3 22.6 6.2 0.3 0.0 5.3 EEF1A2 "EEF1AL, HS1, STN, STNL" ENSG00000101210 "Eukaryotic translation elongation factor 1 alpha 2" Q05639 20 63488013-63499239 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 1638.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 130.8;Cardiomyocytes: 125.5;Horizontal cells: 269.2;Rod photoreceptor cells: 50.9;Skeletal myocytes: 49.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 347.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 240.0;MCF7: 405.9;SCLC-21H: 187.0;T-47d: 157.2;U-2 OS: 202.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034019, HPA051759, HPA053862, HPA056990" Approved Approved Nucleoli,Cytosol NA NA 55000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 37: Myocytes - Muscle contraction" Cytosol Nucleoli "CAB034019: AB_1562672, HPA051759: AB_2681595, HPA053862: AB_2797248, HPA056990: AB_2683302" "unprognostic (1.40e-2)" "unprognostic (6.82e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (5.17e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (4.85e-1)" "unprognostic (1.68e-1)" "unprognostic (3.02e-2)" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (2.30e-1)" "unprognostic (1.86e-1)" "unprognostic (8.29e-3)" "unprognostic (1.82e-1)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" 0.9 32.7 59.3 1.4 81.3 0.0 1.7 17.1 347.2 2.8 0.0 5.1 0.7 0.3 1.1 9.7 0.4 2.4 358.0 73.4 97.3 1.3 3.0 0.8 0.6 95.0 2.9 0.5 6.5 16.2 111.5 0.0 76.3 9.6 0.4 37.2 19.5 0.8 1638.0 6.8 1.9 0.8 0.0 0.3 8.5 1.2 30.7 0.2 0.7 320.7 0.1 2.2 1.8 125.0 0.5 71.0 0.8 16.8 0.0 0.6 7.9 10.0 1.3 51.6 16.3 9.8 41.5 0.0 110.4 0.5 13.4 38.8 240.0 0.7 115.9 0.5 13.1 0.0 24.1 4.1 2.9 0.0 13.4 1.4 2.2 0.1 1.0 0.2 0.0 0.0 3.4 0.2 0.5 405.9 1.4 0.5 11.4 95.6 96.5 8.0 0.2 10.2 2.4 3.9 187.0 89.9 90.0 12.6 1.6 2.2 157.2 3.8 0.0 0.3 202.9 0.7 1.8 0.3 0.9 1.4 0.9 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 59.3 81.3 17.1 347.2 73.4 97.3 95.0 2.9 76.3 0.0 30.7 125.0 0.1 0.0 0.0 9.4 0.7 0.4 0.9 0.0 0.0 130.8 11.8 4.6 125.5 1.5 0.6 0.0 12.5 0.0 1.1 0.4 0.0 1.3 0.2 0.5 0.3 2.2 0.0 0.0 35.5 0.2 0.2 3.6 4.6 1.4 5.7 1.0 1.1 0.1 0.0 269.2 37.2 0.0 0.0 0.3 0.7 0.5 0.0 0.6 0.0 15.0 0.0 11.7 0.0 14.6 12.7 0.3 0.0 0.0 0.3 2.6 0.0 0.5 0.0 50.9 0.0 49.9 3.4 0.0 0.3 0.0 1.8 0.0 1.5 0.0 0.5 1.1 EFHC2 "FLJ22843, MRX74" ENSG00000183690 "EF-hand domain containing 2" Q5JST6 X 44147872-44343672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 17.1;fallopian tube: 14.7" "Cell type enhanced" "Detected in many" "Astrocytes: 32.0;Early spermatids: 78.6;Endometrial ciliated cells: 55.3;Respiratory ciliated cells: 79.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 16.4;NK-cell: 5.8" "Group enriched" "Detected in many" 7 "granulocytes: 16.4;NK-cells: 5.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.7;HEL: 3.7;HMC-1: 12.0;NB-4: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034492 Approved Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane" "HPA034492: AB_10671227" "unprognostic (1.93e-1)" "unprognostic (7.80e-3)" "unprognostic (7.35e-2)" "unprognostic (2.75e-1)" "unprognostic (6.83e-3)" "unprognostic (5.07e-2)" "unprognostic (4.29e-2)" "unprognostic (1.75e-2)" "unprognostic (3.50e-2)" "unprognostic (2.90e-2)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (7.89e-2)" "unprognostic (1.06e-1)" "unprognostic (6.13e-4)" "unprognostic (1.64e-3)" "unprognostic (4.97e-2)" 0.4 0.3 1.5 0.3 1.9 1.4 0.7 1.0 1.4 2.7 17.1 1.1 0.3 3.7 3.4 1.8 14.7 1.4 3.7 1.5 2.1 1.8 0.0 2.0 0.2 5.2 3.9 1.7 0.1 0.2 3.1 0.8 2.8 1.9 0.3 2.0 8.2 3.6 0.0 3.5 0.5 1.6 2.7 0.3 0.9 6.7 2.5 0.5 2.3 0.1 0.4 0.5 0.9 2.6 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 3.7 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 12.0 0.2 0.2 0.1 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.0 0.0 1.9 0.4 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.2 0.4 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 16.4 0.0 0.0 1.5 0.0 0.6 0.1 0.6 0.1 0.3 0.1 0.5 0.7 1.5 5.8 0.0 0.0 0.0 0.9 1.5 1.9 1.0 1.4 1.5 2.1 5.2 3.9 2.8 2.7 2.5 2.6 0.1 0.0 3.9 32.0 0.0 3.1 6.0 9.6 1.2 0.2 0.4 0.5 10.8 4.3 5.1 0.0 2.1 0.0 1.6 1.2 1.9 0.9 78.6 55.3 6.0 0.3 0.0 1.7 7.2 5.9 0.1 0.8 0.0 17.1 16.4 3.8 0.4 0.0 0.3 0.0 1.7 1.5 4.1 0.0 0.4 19.0 6.8 4.9 0.0 0.0 0.4 5.3 3.1 1.5 0.2 1.0 0.0 7.2 0.2 1.0 3.8 0.7 79.6 0.1 6.6 0.1 3.7 11.3 10.5 7.3 2.8 0.3 1.6 0.4 5.2 6.0 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 EIF1B GC20 ENSG00000114784 "Eukaryotic translation initiation factor 1B" O60739 3 40309707-40312424 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 362.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.54e-1)" "unprognostic (1.06e-2)" "unprognostic (1.31e-2)" "unprognostic (3.20e-3)" "unprognostic (7.64e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.16e-2)" "unprognostic (9.87e-2)" "unprognostic (3.02e-2)" "unprognostic (1.13e-2)" "unprognostic (2.17e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (1.82e-1)" "unprognostic (8.87e-2)" 81.6 92.0 88.1 47.8 90.5 221.8 66.7 97.3 134.4 64.2 76.7 78.2 41.2 66.8 59.9 41.9 75.1 61.3 362.7 90.7 123.2 118.4 92.4 73.9 67.7 110.8 98.4 103.3 60.3 77.2 91.0 53.0 106.6 52.3 42.2 94.5 47.9 56.5 157.4 47.7 55.5 59.1 93.3 62.6 70.9 83.3 92.3 62.7 59.2 146.5 59.8 89.9 53.7 99.7 41.1 33.1 110.0 62.9 130.2 127.0 65.6 82.1 107.6 79.8 103.0 52.1 54.1 83.7 44.5 56.4 47.8 27.3 75.9 40.4 80.8 127.6 76.9 135.5 33.4 120.4 206.3 82.4 66.8 93.0 121.8 70.2 119.2 112.5 85.2 55.9 115.5 100.5 93.2 26.1 66.7 89.2 149.5 36.3 87.0 45.4 61.4 68.1 78.3 51.6 46.7 76.5 59.4 34.1 238.6 103.4 43.6 82.8 65.8 45.8 47.3 93.6 58.5 92.5 177.2 121.4 57.3 89.7 66.6 93.0 48.5 138.1 36.4 57.8 43.6 95.1 44.4 47.0 45.3 83.8 51.8 45.8 133.2 40.9 55.7 73.2 58.4 41.0 88.1 90.5 97.3 134.4 90.7 123.2 110.8 98.4 106.6 93.3 92.3 99.7 178.9 93.0 63.1 15.7 216.5 190.0 226.5 133.8 227.1 108.6 94.7 119.0 454.8 81.5 83.3 88.3 54.2 113.9 125.0 114.3 293.5 97.2 167.3 139.6 146.0 115.5 117.5 294.1 45.2 114.6 120.2 207.4 69.8 141.5 130.0 104.3 102.1 75.1 128.5 149.7 50.9 82.1 99.7 172.0 135.4 71.5 109.0 192.1 149.4 20.6 138.0 157.5 118.4 23.1 33.4 85.0 183.6 91.7 76.9 119.8 138.7 292.1 81.5 189.8 92.1 161.7 187.6 493.0 268.2 137.8 147.8 115.6 143.4 80.9 88.7 206.7 EIF3K "ARG134, EIF3S12, HSPC029, M9, PLAC-24, PRO1474, PTD001" ENSG00000178982 "Eukaryotic translation initiation factor 3 subunit K" Q9UBQ5 19 38619082-38636955 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045446, HPA054590" Uncertain Supported Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" Cytosol "HPA045446: AB_10962716, HPA054590: AB_2682534" "unprognostic (7.07e-3)" "prognostic favorable (1.31e-4)" "unprognostic (3.04e-2)" "unprognostic (2.10e-3)" "unprognostic (1.67e-2)" "unprognostic (3.16e-1)" "unprognostic (2.25e-2)" "unprognostic (3.17e-1)" "unprognostic (1.46e-1)" "unprognostic (7.06e-3)" "unprognostic (2.92e-2)" "unprognostic (4.26e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.82e-1)" "unprognostic (1.00e-1)" "unprognostic (6.49e-2)" "unprognostic (3.69e-2)" 233.4 177.9 98.8 83.6 100.4 172.7 228.3 104.9 114.2 214.3 113.1 285.5 142.0 186.6 110.2 286.1 188.4 73.2 591.7 98.9 100.9 313.3 189.0 169.3 142.0 103.2 101.7 214.8 262.2 179.6 173.0 72.0 101.0 172.1 165.7 57.9 197.5 100.4 682.7 290.7 219.1 113.7 102.1 222.5 265.7 66.5 103.7 143.7 168.6 462.4 182.1 218.4 216.6 105.3 135.3 421.3 110.1 175.4 196.5 197.7 134.3 104.2 180.7 220.9 192.5 272.0 118.6 300.2 121.2 174.2 128.7 122.4 221.2 280.8 165.1 145.7 184.6 214.0 134.4 197.2 201.0 345.1 170.7 219.6 252.3 151.4 269.6 118.8 242.3 156.6 217.9 250.8 188.8 215.2 185.3 158.6 103.5 474.4 211.4 222.7 197.0 235.7 225.3 311.0 141.5 139.4 114.8 377.1 174.0 117.3 145.9 260.3 133.9 135.0 134.8 81.3 185.9 246.4 276.3 255.6 114.9 321.6 155.0 154.8 267.8 138.2 182.8 297.8 232.1 252.0 222.3 213.2 359.0 218.0 228.9 204.0 72.4 201.2 305.7 209.4 296.4 441.8 98.8 100.4 104.9 114.2 98.9 100.9 103.2 101.7 101.0 102.1 103.7 105.3 372.1 93.0 166.1 26.4 430.3 395.6 547.4 674.4 345.4 83.6 477.2 755.1 502.5 320.3 331.0 217.0 66.7 422.9 376.3 466.2 1097.6 345.5 160.6 182.0 231.8 309.3 326.1 284.2 23.8 453.2 484.8 267.7 231.9 180.6 248.2 239.0 311.7 278.6 660.9 23.5 25.0 567.7 305.2 640.7 552.1 274.4 265.3 470.7 466.0 10.3 572.6 276.9 415.1 14.6 24.7 330.2 487.2 199.7 386.6 461.9 874.5 974.2 198.3 174.9 203.8 331.4 450.3 109.0 83.4 594.2 457.0 454.1 424.0 319.1 719.5 622.7 ENDOG ENSG00000167136 "Endonuclease G" Q14249 9 128818500-128822676 "Plasma proteins, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 135.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 111.4;Late spermatids: 147.4;Respiratory ciliated cells: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021335, HPA021830" Approved "Intracellular and membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA021335: AB_1848151, HPA021830: AB_1848152" "unprognostic (1.35e-1)" "unprognostic (3.41e-1)" "unprognostic (4.86e-2)" "prognostic favorable (5.12e-4)" "unprognostic (2.51e-1)" "unprognostic (3.95e-1)" "unprognostic (6.56e-2)" "unprognostic (2.64e-2)" "unprognostic (4.90e-1)" "unprognostic (6.97e-2)" "unprognostic (8.35e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.06e-7)" "unprognostic (1.69e-2)" "unprognostic (1.81e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" 11.2 18.8 19.7 2.9 20.0 4.4 11.9 23.7 25.1 9.3 27.0 16.8 12.5 9.3 1.8 17.5 12.6 1.7 52.2 20.1 22.5 24.3 52.9 9.9 3.3 23.4 20.8 8.1 22.5 12.0 13.7 3.6 19.5 14.9 5.7 2.0 14.9 7.0 135.2 13.6 11.5 3.0 20.3 9.2 18.4 20.6 22.6 3.8 11.9 59.1 3.1 11.8 11.0 22.9 14.2 15.3 3.9 20.7 10.0 8.5 17.5 13.4 6.9 12.4 8.6 9.3 11.2 4.6 11.9 8.8 7.7 39.6 12.5 11.8 2.2 9.0 22.4 8.0 14.6 16.7 4.5 24.8 29.3 8.9 14.1 7.5 5.1 7.6 9.6 15.2 25.4 7.1 7.9 20.9 19.4 51.1 9.7 24.6 56.4 22.9 4.5 48.2 18.8 5.1 34.0 33.8 30.0 27.2 7.4 2.6 26.1 12.2 9.8 8.7 5.2 12.5 10.2 22.2 3.3 8.9 17.5 17.6 9.1 0.0 1.1 0.7 1.3 2.0 1.2 1.5 1.3 0.6 1.8 2.8 1.2 1.4 0.0 1.3 0.9 3.6 0.6 0.6 19.7 20.0 23.7 25.1 20.1 22.5 23.4 20.8 19.5 20.3 22.6 22.9 19.0 9.6 5.5 13.1 11.4 8.8 26.9 12.8 6.2 14.0 28.7 21.7 0.6 20.0 16.8 23.9 4.2 31.9 26.9 55.1 101.8 6.0 97.1 111.4 15.1 9.3 14.4 16.8 4.6 7.9 34.4 14.9 21.4 30.1 1.3 93.0 10.0 80.3 20.0 11.8 8.3 27.2 18.3 17.7 7.7 147.4 18.6 15.6 10.6 4.7 6.4 37.2 10.3 3.0 7.8 7.8 24.1 18.8 11.0 18.4 52.0 108.2 115.1 13.1 6.6 23.7 19.0 74.9 6.6 19.1 14.5 10.1 14.5 44.5 36.6 23.3 EPB41L4B "EHM2, LULU2" ENSG00000095203 "Erythrocyte membrane protein band 4.1 like 4B" Q9H329 9 109171974-109321059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.9;pancreas: 149.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 134.8;Excitatory neurons: 79.7;Hepatocytes: 125.2;Proximal enterocytes: 79.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 31.7;hTCEpi: 49.8;OE19: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042862 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA042862: AB_10794534" "prognostic unfavorable (1.02e-4)" "unprognostic (6.58e-2)" "unprognostic (2.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" "unprognostic (6.19e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (3.60e-1)" "unprognostic (6.20e-2)" "unprognostic (8.82e-4)" "unprognostic (1.46e-3)" "unprognostic (1.43e-1)" "unprognostic (4.65e-2)" "unprognostic (1.29e-1)" 21.0 9.7 6.0 4.5 8.7 0.0 15.3 2.0 12.2 4.1 11.8 57.6 47.6 1.2 17.9 1.5 10.8 4.2 8.8 10.7 6.4 6.4 88.9 6.3 0.2 2.7 5.3 13.8 149.1 11.1 1.6 2.5 3.7 7.6 56.7 3.0 26.9 9.1 6.1 15.5 51.9 1.9 7.2 0.1 30.6 7.5 10.9 0.6 44.7 0.7 1.6 2.2 3.4 4.3 8.7 10.8 0.7 0.8 0.8 0.0 31.7 1.1 0.4 3.7 1.9 18.5 8.5 0.0 2.3 1.0 8.9 13.9 21.5 11.5 3.9 9.2 5.1 0.0 3.4 26.5 2.2 0.4 0.0 0.3 49.8 1.5 17.0 1.1 0.2 8.0 0.3 0.0 5.2 22.3 0.4 0.2 13.8 62.8 15.7 0.0 0.0 0.6 12.9 13.1 13.1 1.4 3.4 22.2 0.0 6.3 5.2 0.1 0.5 7.5 7.6 2.5 3.1 0.1 0.1 0.0 5.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 8.7 2.0 12.2 10.7 6.4 2.7 5.3 3.7 7.2 10.9 4.3 0.2 6.4 5.1 2.6 0.4 11.5 5.4 6.0 1.2 7.5 22.7 10.4 18.5 20.0 9.6 7.3 0.0 4.1 0.0 134.8 0.0 3.5 11.7 23.8 2.3 0.8 51.6 0.0 79.7 20.8 2.1 2.5 26.0 20.7 0.0 6.2 5.0 125.2 0.6 38.7 58.9 51.4 12.2 1.6 1.5 1.9 13.4 0.4 1.8 3.7 0.0 1.9 0.0 12.1 3.8 10.2 54.4 2.6 0.0 7.2 79.2 0.8 39.2 1.1 0.0 0.8 1.0 1.4 17.2 0.9 24.0 1.9 0.5 6.8 46.5 6.5 EPHX2 ABHD20 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 333.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 180.0;Hepatocytes: 131.5;Proximal enterocytes: 399.0;Proximal tubular cells: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.0;naive CD4 T-cell: 106.7;naive CD8 T-cell: 50.4;T-reg: 29.6" "Lineage enriched" "Detected in many" 23 "T-cells: 106.7" "Cell line enhanced" "Detected in many" "JURKAT: 139.4;K-562: 51.6;OE19: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 19.3 74.0 14.5 9.1 15.0 1.9 30.1 14.4 14.1 21.0 42.2 61.4 112.8 17.7 27.2 38.6 41.6 9.4 29.1 13.2 15.3 166.3 333.2 11.2 17.2 16.1 17.3 38.0 64.5 54.8 35.8 8.5 15.9 64.6 57.6 21.5 36.5 27.2 16.2 43.4 128.4 15.4 15.8 10.8 23.4 9.0 15.8 65.9 22.6 13.8 20.8 19.7 23.4 15.7 15.3 10.1 6.3 8.1 0.4 0.0 4.8 1.3 0.9 0.7 0.2 8.0 10.1 0.1 5.9 4.1 3.2 10.7 1.1 2.6 0.5 0.0 4.7 22.5 1.1 24.8 3.4 0.1 4.5 8.6 10.7 0.1 1.1 2.5 0.5 139.4 51.6 0.2 0.0 4.7 14.9 0.5 10.1 102.4 17.2 0.1 0.1 0.4 8.7 2.2 5.1 16.0 12.1 14.2 15.0 4.6 21.8 4.2 0.2 0.0 3.8 1.8 0.1 12.5 10.1 0.2 0.4 0.1 0.1 0.1 0.1 0.0 7.8 0.0 11.3 4.5 35.0 12.7 0.1 2.5 106.7 50.4 0.2 4.6 0.1 0.2 29.6 20.0 14.5 15.0 14.4 14.1 13.2 15.3 16.1 17.3 15.9 15.8 15.8 15.7 6.3 6.4 17.0 16.3 6.1 11.9 18.6 10.1 29.6 34.1 17.2 18.4 23.7 20.0 9.7 27.6 79.2 22.8 1.0 82.7 180.0 8.8 7.5 6.9 4.8 9.4 23.4 3.8 3.0 6.4 2.5 12.1 15.8 1.5 5.7 17.4 17.5 131.5 2.2 33.7 7.2 63.4 2.0 4.6 1.2 4.8 29.8 3.6 5.4 2.8 2.6 91.5 3.1 7.5 5.1 3.1 83.7 18.8 4.5 20.5 399.0 259.3 24.1 52.4 0.0 11.5 10.2 1.3 13.9 39.2 18.3 8.2 11.9 78.5 101.3 10.8 EPM2A "LD, LDE" ENSG00000112425 "EPM2A glucan phosphatase, laforin" O95278 6 145382535-145736023 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Glycogen storage disease, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.8;tongue: 79.5" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Early spermatids: 33.0;Excitatory neurons: 30.4;Inhibitory neurons: 50.7;Oligodendrocyte precursor cells: 56.8;Oligodendrocytes: 60.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 23.2" "Low region specificity" "Detected in all" "HPA053643, HPA055468" Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA053643: AB_2797247, HPA055468: AB_2797252" "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.34e-3)" "unprognostic (2.92e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.52e-4)" "unprognostic (2.28e-1)" "prognostic favorable (4.08e-7)" "unprognostic (4.12e-4)" "unprognostic (2.17e-1)" "unprognostic (2.99e-3)" "unprognostic (1.23e-1)" 5.8 6.0 11.4 1.5 11.7 1.8 3.2 11.9 17.8 3.1 7.3 17.2 3.2 6.0 4.3 9.3 4.4 3.6 24.4 11.6 12.6 8.5 5.7 3.0 3.3 11.9 11.5 5.7 2.4 5.2 3.8 1.5 11.1 6.1 2.9 12.1 3.1 8.8 76.8 2.1 3.8 6.3 10.3 2.1 5.3 3.0 11.5 4.8 3.9 79.5 2.6 9.8 2.7 13.3 1.3 2.1 3.4 6.6 8.6 2.3 1.6 3.1 3.8 2.9 3.5 1.7 1.7 23.2 2.7 3.8 3.5 1.8 1.3 1.6 2.6 9.3 1.9 3.6 2.5 2.7 4.8 12.7 2.4 2.0 7.0 1.7 0.7 3.8 2.0 5.0 1.8 5.4 3.8 3.1 8.4 3.2 3.9 3.2 1.9 4.8 3.1 6.7 2.5 1.8 6.3 6.4 5.5 3.3 7.8 3.1 1.9 7.3 4.6 2.9 1.1 2.7 2.6 4.1 4.6 8.6 2.6 2.8 4.8 0.0 0.0 0.0 0.1 0.5 0.4 0.4 0.4 0.3 0.3 0.4 0.4 0.9 0.1 1.9 0.1 0.3 0.0 0.3 11.4 11.7 11.9 17.8 11.6 12.6 11.9 11.5 11.1 10.3 11.5 13.3 3.9 6.4 1.5 66.9 4.4 0.9 1.0 0.8 0.6 8.4 3.5 2.2 27.8 2.8 2.2 1.8 6.2 1.0 1.9 0.2 11.7 1.0 33.0 1.9 3.6 2.2 1.2 4.4 30.4 2.3 0.7 2.3 1.1 1.4 2.5 6.0 1.4 6.6 2.3 30.3 50.7 1.5 2.0 3.3 1.4 19.8 3.1 3.1 7.2 15.9 1.7 7.9 2.1 56.8 60.1 1.2 1.7 2.2 1.7 1.5 0.5 7.1 2.2 6.3 0.0 6.2 2.4 4.9 1.6 0.8 0.4 0.4 1.8 5.1 1.2 0.3 ETFDH ETFQO ENSG00000171503 "Electron transfer flavoprotein dehydrogenase" Q16134 4 158672125-158709623 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Disease variant, FDA approved drug targets, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.4;tongue: 186.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 146.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041978 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA041978: AB_10795605" "unprognostic (7.19e-2)" "unprognostic (2.28e-1)" "unprognostic (2.90e-2)" "unprognostic (5.92e-3)" "unprognostic (1.91e-1)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-2)" "prognostic favorable (5.76e-10)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (8.85e-3)" "unprognostic (1.74e-1)" 34.6 38.0 13.3 10.7 14.8 9.4 16.0 13.9 15.1 10.2 25.5 32.6 63.7 10.4 8.4 25.0 9.3 11.1 93.3 12.8 14.5 46.5 196.4 9.2 8.7 12.3 13.8 10.8 20.4 32.8 9.8 13.0 12.8 13.7 26.9 15.8 21.8 13.2 111.0 18.7 51.4 14.8 12.5 9.5 26.9 11.2 15.0 9.4 13.2 186.9 14.3 12.9 12.8 15.1 13.2 9.2 12.2 21.4 47.2 28.8 6.6 21.3 19.4 13.9 14.3 3.7 24.6 27.8 4.6 24.1 15.8 13.8 22.1 20.9 19.2 51.5 20.3 26.5 17.3 8.0 20.8 24.0 23.4 26.5 23.8 15.8 12.8 20.8 27.3 20.7 15.6 53.8 22.2 14.7 22.7 11.0 5.0 33.2 19.4 18.4 4.3 21.9 21.2 10.6 18.7 8.0 21.0 39.5 21.8 10.0 30.4 17.6 13.6 11.9 6.7 18.5 12.2 31.3 42.1 20.3 24.6 19.2 13.5 3.7 21.5 41.5 10.1 22.6 12.7 10.3 9.8 10.4 18.3 9.6 11.6 9.9 7.8 10.5 20.9 13.1 16.1 9.5 13.3 14.8 13.9 15.1 12.8 14.5 12.3 13.8 12.8 12.5 15.0 15.1 18.1 12.8 10.3 55.2 18.5 33.0 46.0 27.2 29.6 29.2 12.6 13.8 146.6 14.3 22.8 18.4 64.6 24.9 18.0 34.4 29.4 14.4 4.2 12.5 12.5 17.7 18.0 30.7 43.2 11.7 9.9 23.9 44.4 14.2 5.1 19.2 12.8 85.7 13.4 25.2 71.9 22.5 30.5 14.4 15.8 4.7 23.0 13.3 8.8 15.0 12.2 13.9 10.3 55.8 58.0 11.7 29.4 23.7 30.1 21.3 58.3 26.8 13.1 43.9 32.9 27.4 30.4 43.2 29.8 32.7 36.9 43.0 19.7 15.7 26.2 38.7 EXOG "ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b" ENSG00000157036 "Exo/endonuclease G" Q9Y2C4 3 38496127-38542161 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 59.8;Rod photoreceptor cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012531, HPA071050" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA012531: AB_2732403, HPA071050: " "unprognostic (2.88e-1)" "unprognostic (5.81e-3)" "unprognostic (3.55e-3)" "unprognostic (2.77e-1)" "unprognostic (8.32e-3)" "unprognostic (8.90e-3)" "unprognostic (4.78e-4)" "unprognostic (3.59e-2)" "unprognostic (3.99e-2)" "unprognostic (3.10e-2)" "prognostic favorable (1.92e-5)" "prognostic unfavorable (4.90e-4)" "unprognostic (6.51e-2)" "unprognostic (1.64e-2)" "unprognostic (4.79e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" 3.9 5.1 5.5 4.0 5.4 3.9 3.4 7.9 7.0 5.2 3.4 4.9 2.0 4.7 3.5 2.6 3.8 3.5 12.9 5.9 5.1 3.7 3.4 3.8 6.0 5.1 5.7 3.9 3.9 3.3 5.6 2.9 4.5 4.8 3.2 5.3 3.2 3.6 3.2 1.9 4.4 4.5 4.1 5.5 3.6 3.9 5.9 5.0 4.5 3.2 4.7 4.4 3.5 6.4 4.3 7.6 8.7 7.6 5.7 8.4 3.5 13.9 8.7 11.6 12.9 6.8 4.3 15.1 3.5 5.5 3.3 4.3 11.0 4.7 9.8 17.5 10.2 11.4 12.7 7.6 7.0 12.7 9.5 6.4 5.2 10.3 5.4 5.5 16.2 8.6 5.2 9.9 18.2 2.9 8.6 4.2 8.3 3.7 9.8 5.8 4.6 6.7 6.0 5.5 4.0 2.0 8.5 2.1 3.8 3.9 2.9 6.1 13.3 9.5 7.2 10.8 11.2 5.7 10.3 13.3 7.4 10.9 7.1 0.9 10.0 4.5 26.6 9.8 23.8 60.3 25.8 26.4 7.2 47.1 25.9 25.2 0.6 27.8 11.6 14.4 12.9 5.5 5.5 5.4 7.9 7.0 5.9 5.1 5.1 5.7 4.5 4.1 5.9 6.4 9.8 6.4 4.5 15.3 24.9 2.9 6.5 13.4 8.0 49.9 4.4 3.7 33.0 7.2 5.8 11.0 56.3 12.3 23.8 5.4 0.0 8.5 3.7 3.2 9.7 12.9 16.9 13.7 23.5 5.3 2.1 10.8 4.6 3.6 1.3 14.0 9.7 5.7 7.0 40.4 29.1 7.5 10.2 8.3 6.2 3.7 27.1 6.0 12.4 15.0 16.0 13.0 59.8 31.7 23.5 6.4 7.4 17.7 19.1 5.5 4.3 4.0 8.0 78.3 13.1 11.6 9.5 36.5 28.0 4.6 1.0 1.9 22.9 14.0 9.7 6.3 EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.2;skeletal muscle: 12.7;tongue: 29.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Breast glandular cells: 8.8;Excitatory neurons: 22.7;Horizontal cells: 10.1;Melanocytes: 7.2;Oligodendrocyte precursor cells: 10.6" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Group enriched" "Detected in many" 11 "amygdala: 10.3;basal ganglia: 9.8;cerebral cortex: 14.2;hippocampal formation: 11.5;white matter: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010726, HPA037749" Uncertain Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 79000 "Cluster 47: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" Centrosome Vesicles "HPA010726: , HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" 0.2 1.0 10.3 0.0 9.8 0.0 0.8 0.0 14.2 0.4 0.0 1.0 0.1 3.6 0.1 0.5 0.7 0.3 3.5 11.5 0.0 0.4 0.0 0.2 0.2 0.1 0.6 1.1 1.5 0.0 0.9 0.3 0.4 0.4 0.0 0.8 0.5 0.2 12.7 2.3 0.3 1.3 0.0 3.5 0.3 0.6 0.9 0.0 0.2 29.8 0.0 0.3 0.4 6.9 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.2 0.6 0.0 0.2 2.4 0.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 9.8 0.0 14.2 11.5 0.0 0.1 0.6 0.4 0.0 0.9 6.9 0.1 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 15.3 8.8 1.8 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 22.7 0.0 0.0 0.4 0.0 0.2 0.0 0.4 0.0 0.0 0.1 10.1 5.1 0.0 0.0 0.0 0.3 0.6 1.5 0.0 7.2 2.8 0.0 0.4 0.0 10.6 1.9 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.4 0.4 0.2 0.2 0.0 0.0 1.0 0.0 1.1 0.1 0.1 EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 18.7;parathyroid gland: 23.7" "Cell type enriched" "Detected in some" 11 "Astrocytes: 214.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 27.6;RH-30: 21.3;RPMI-8226: 9.5;SH-SY5Y: 51.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 20.7" HPA028917 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA028917: AB_2672826" "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.95e-2)" "unprognostic (9.17e-2)" "unprognostic (2.91e-4)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (1.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-12)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (3.81e-4)" "unprognostic (1.25e-2)" 0.6 0.6 2.8 0.1 7.8 0.0 0.2 0.5 2.1 5.1 18.7 0.1 0.1 0.1 0.1 0.4 2.0 0.3 4.5 1.3 2.5 0.1 0.0 0.4 0.0 2.1 4.9 0.2 0.0 23.7 10.8 0.0 2.3 12.0 0.2 0.4 0.8 4.0 2.8 0.0 0.2 0.2 0.0 0.1 0.8 0.8 4.6 11.7 0.6 2.5 0.1 2.6 4.3 0.6 0.2 0.0 6.4 27.6 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 1.6 0.0 0.0 4.7 0.0 2.2 0.0 0.0 0.5 0.0 6.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 1.0 0.0 0.0 0.0 2.0 0.0 1.5 0.0 21.3 9.5 0.0 0.0 2.2 51.4 0.0 0.0 1.6 5.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 6.3 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 7.8 0.5 2.1 1.3 2.5 2.1 4.9 2.3 0.0 4.6 0.6 0.2 0.0 0.0 214.5 0.0 0.1 0.0 6.4 0.6 0.1 0.0 0.1 8.8 0.0 7.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 4.4 3.1 0.1 0.2 0.0 0.0 1.3 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 13.5 0.0 2.0 0.0 0.0 6.4 0.3 0.0 0.0 11.2 0.0 0.1 0.0 18.6 0.6 0.0 0.0 0.4 0.0 0.1 0.0 0.3 10.5 0.2 0.0 0.2 0.5 0.8 1.0 1.1 0.1 0.5 0.0 1.4 0.0 0.1 FABP6 "I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP" ENSG00000170231 "Fatty acid binding protein 6" P51161 5 160187367-160238735 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 84 "intestine: 4531.3" "Cell type enriched" "Detected in some" 23 "Proximal enterocytes: 52213.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 31.6;EFO-21: 30.5;HDLM-2: 13.6;NB-4: 17.0;RPMI-8226: 17.2;RT4: 15.2;U-2197: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA012601, CAB024713" Enhanced "Intracellular and membrane" NA NA 890000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "CAB024713: , HPA012601: AB_1848435" "unprognostic (3.03e-2)" "unprognostic (7.55e-2)" "unprognostic (1.27e-1)" "unprognostic (5.00e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (5.35e-7)" "unprognostic (3.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.41e-2)" "unprognostic (2.16e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.35e-9)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (2.48e-1)" "unprognostic (1.85e-3)" 0.0 14.4 7.9 2.5 8.1 0.1 0.2 8.3 11.7 3.1 8.7 3.3 4.9 1.9 0.0 1.2 53.9 0.2 2.2 7.4 11.2 0.2 0.1 5.3 4.2 8.9 8.5 0.1 0.1 0.0 0.7 0.1 10.4 0.2 0.0 0.9 0.2 0.2 0.0 0.4 4531.3 3.4 9.4 1.5 0.4 3.1 9.4 5.6 0.1 1.4 3.5 2.7 0.4 7.7 0.3 0.6 0.0 0.2 0.0 0.0 11.4 0.0 0.0 0.0 0.0 8.1 1.3 31.6 30.5 0.0 0.3 0.0 0.0 0.0 0.0 13.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.5 0.0 0.0 2.3 1.2 0.4 0.0 0.0 0.0 17.0 0.1 0.0 2.9 0.0 1.0 17.2 0.0 15.2 2.8 0.7 0.0 8.8 0.2 0.1 0.2 0.2 0.0 0.0 0.1 15.3 1.7 1.7 6.9 4.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 8.1 8.3 11.7 7.4 11.2 8.9 8.5 10.4 9.4 9.4 7.7 0.0 0.0 1.5 1.3 0.2 0.5 0.3 7.8 0.6 0.2 0.1 0.1 3.4 0.0 21.9 0.0 0.0 0.0 0.0 0.6 0.0 0.9 0.4 110.2 0.6 0.1 0.0 0.0 1.6 0.0 0.3 0.6 0.0 1.4 0.0 0.6 0.0 0.0 0.1 1.7 2.2 2244.4 2.0 0.0 4.2 0.2 0.3 0.4 0.0 0.0 0.6 0.2 0.0 0.0 0.9 0.3 2080.0 0.0 0.0 0.1 52213.9 0.1 134.9 0.7 0.0 0.0 1.2 0.1 2.1 2.0 0.1 0.0 0.1 1.7 1304.0 1.4 FAHD2B DKFZp434N062 ENSG00000144199 "Fumarylacetoacetate hydrolase domain containing 2B" Q6P2I3 2 97083583-97094882 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 235.0;Late spermatids: 212.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 8.8;NK-cells: 16.2;T-cells: 15.5" "Low cell line specificity" "Detected in many" "HPA042145, HPA044987" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "HPA042145: AB_2677873, HPA044987: AB_2679170" "unprognostic (6.55e-3)" "unprognostic (5.56e-1)" "unprognostic (2.01e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (9.03e-3)" "unprognostic (4.13e-3)" "unprognostic (8.84e-3)" "unprognostic (1.59e-1)" "unprognostic (1.41e-1)" "unprognostic (8.65e-3)" "unprognostic (1.94e-1)" "unprognostic (7.67e-2)" "unprognostic (1.48e-1)" "unprognostic (5.03e-2)" "unprognostic (6.26e-3)" "unprognostic (2.04e-1)" 10.7 7.1 24.5 3.2 28.2 3.5 12.8 29.5 25.2 16.6 21.1 14.5 2.5 17.6 38.1 7.4 17.2 4.2 30.0 23.7 28.8 12.6 4.0 7.9 5.7 27.8 25.8 23.6 14.4 11.1 10.3 1.7 28.9 10.9 5.5 6.8 10.8 6.8 30.3 13.6 8.2 11.2 29.6 6.8 24.7 46.8 28.6 4.2 3.9 45.9 7.7 14.3 12.2 33.1 5.0 6.0 8.2 16.8 8.0 9.5 13.0 4.3 5.0 7.3 6.7 5.6 7.7 9.6 3.7 1.7 13.7 5.2 12.0 9.6 4.1 12.5 22.1 10.5 7.6 4.5 25.6 11.9 6.5 12.8 10.0 0.9 15.5 3.4 7.8 37.0 18.3 22.9 0.5 0.0 14.5 35.5 8.1 2.2 16.7 14.0 2.3 34.5 8.1 8.3 1.8 7.1 14.7 3.8 21.5 15.3 16.1 9.4 1.3 0.8 13.7 1.0 4.2 15.1 21.1 25.4 1.2 30.5 10.1 0.0 0.2 0.2 11.3 0.3 15.5 8.8 11.0 11.1 1.8 4.2 7.5 9.7 0.2 16.2 0.1 2.9 15.0 4.8 24.5 28.2 29.5 25.2 23.7 28.8 27.8 25.8 28.9 29.6 28.6 33.1 8.2 6.4 11.1 11.1 6.1 6.5 11.5 5.9 9.6 6.3 17.9 21.0 42.3 4.3 8.0 5.5 2.1 2.1 5.8 1.1 27.4 7.3 235.0 2.3 6.5 7.8 1.8 5.5 10.4 4.3 1.0 13.5 30.1 1.2 5.7 18.5 8.2 2.3 3.5 5.0 12.1 3.3 6.1 1.6 2.6 212.6 17.1 2.2 30.2 2.8 1.6 21.7 9.2 2.5 8.0 6.9 1.2 17.0 17.3 7.7 0.2 3.8 4.6 5.8 0.0 9.7 10.5 24.5 7.3 7.3 7.1 1.0 8.2 11.1 4.4 8.3 FAM151A "C1orf179, MGC27169" ENSG00000162391 "Family with sequence similarity 151 member A" Q8WW52 1 54609181-54623556 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 66.3;kidney: 174.5" "Group enriched" "Detected in some" 15 "Proximal enterocytes: 478.5;Proximal tubular cells: 294.8" "Group enriched" "Detected in many" 5 "liver cancer: 2.3;renal cancer: 3.2;testis cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 44 "CACO-2: 78.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA016840 Approved NA NA 10000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA016840: AB_2669461" "unprognostic (1.89e-1)" "unprognostic (6.90e-3)" "unprognostic (3.73e-2)" "unprognostic (1.97e-6)" "unprognostic (1.71e-2)" "unprognostic (4.84e-3)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.05e-2)" "unprognostic (4.91e-3)" "unprognostic (9.99e-2)" "prognostic favorable (4.09e-5)" "unprognostic (5.85e-2)" "unprognostic (8.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-3)" 0.6 0.3 0.5 0.6 1.5 0.2 0.1 1.6 0.9 0.0 5.9 2.4 2.4 0.1 0.0 0.3 0.0 0.1 3.0 0.6 0.5 174.5 16.7 0.0 5.3 2.7 2.8 0.3 0.6 0.0 0.1 0.0 1.5 0.1 1.3 0.3 0.5 0.0 1.0 0.1 66.3 0.0 0.4 0.8 0.7 0.6 2.2 0.2 0.4 0.0 1.8 0.1 0.0 0.6 0.7 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 78.9 0.9 0.0 0.3 0.0 0.2 1.1 0.0 0.0 0.0 0.5 0.0 1.7 0.4 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.5 0.0 0.0 0.8 0.0 0.0 1.6 0.4 0.5 0.1 0.0 0.0 0.3 0.0 0.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 1.6 0.9 0.6 0.5 2.7 2.8 1.5 0.4 2.2 0.6 0.0 0.0 0.0 3.6 2.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 7.3 0.0 0.0 0.0 9.3 13.7 0.0 5.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.4 16.8 0.0 0.3 0.0 14.3 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 25.0 0.0 0.0 0.0 478.5 294.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.0 0.1 18.1 0.0 FAM155B "CXorf63, TED, TMEM28" ENSG00000130054 "Family with sequence similarity 155 member B" O75949 X 69504326-69532508 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 43.5" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 23.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 7.4;HAP1: 16.2;Hep G2: 6.1;NTERA-2: 24.3;OE19: 6.5;SCLC-21H: 11.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036093 Uncertain NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA036093: AB_10673613" "prognostic unfavorable (4.61e-5)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (5.14e-3)" "unprognostic (1.45e-1)" "unprognostic (2.49e-2)" "unprognostic (3.09e-4)" "unprognostic (7.07e-2)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (1.83e-4)" "prognostic favorable (6.63e-4)" "unprognostic (1.46e-2)" "unprognostic (3.50e-2)" "unprognostic (2.21e-1)" "unprognostic (8.21e-2)" 0.1 0.8 2.2 0.0 2.1 0.0 0.2 3.0 2.6 0.2 0.5 0.3 0.1 0.3 0.4 0.1 0.7 0.2 43.5 2.1 2.7 0.9 0.2 0.1 0.1 2.4 3.1 0.1 1.8 3.1 2.4 0.0 3.4 0.9 0.2 0.4 1.1 4.9 0.1 0.0 0.2 0.1 2.0 0.7 1.1 1.5 3.5 0.1 8.0 0.0 0.1 0.2 0.1 2.3 0.0 2.7 0.2 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.7 0.0 5.2 0.0 0.0 0.0 16.2 0.6 0.0 0.0 5.0 0.0 0.0 6.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.2 0.0 0.0 24.3 6.5 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.8 0.1 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 3.0 2.6 2.1 2.7 2.4 3.1 3.4 2.0 3.5 2.3 0.2 0.0 0.0 1.3 0.0 0.0 0.3 1.6 0.0 0.4 0.6 0.1 23.7 0.0 0.8 1.8 0.0 0.0 0.0 0.5 0.0 0.5 0.0 2.0 0.5 0.7 1.2 0.0 0.8 1.2 0.0 0.4 0.0 4.4 0.0 0.0 0.4 0.3 0.1 0.0 0.9 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.8 0.2 0.0 0.0 1.2 0.0 0.5 0.3 0.8 0.0 0.1 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.3 FAM162A "C3orf28, E2IG5" ENSG00000114023 "Family with sequence similarity 162 member A" Q96A26 3 122384176-122412334 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 625.3;Distal tubular cells: 540.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035856, HPA075611" Approved Supported Mitochondria NA NA 19000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA035856: AB_10611965, HPA075611: " "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (7.84e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (5.91e-3)" "unprognostic (8.74e-2)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "prognostic favorable (3.93e-4)" 49.0 105.7 54.8 31.3 60.2 39.9 43.9 57.3 82.2 84.5 57.1 145.9 56.1 49.5 59.4 207.6 49.7 46.2 174.2 57.1 58.5 107.6 200.3 32.0 32.9 55.9 57.2 84.3 133.9 116.6 51.0 17.6 55.6 74.6 149.0 83.5 59.8 49.2 141.0 89.8 56.3 44.6 56.6 31.7 93.2 43.6 58.8 34.7 44.1 142.6 42.7 76.9 131.5 55.6 132.0 27.7 40.4 75.6 72.1 66.4 20.7 52.9 46.8 49.0 123.9 69.4 58.7 142.1 89.2 18.2 40.3 89.8 73.5 128.1 130.0 74.0 55.1 115.6 44.0 125.8 47.4 114.0 39.6 77.3 65.5 46.7 97.9 164.3 66.0 137.7 79.2 55.6 71.1 52.0 116.9 137.9 59.5 294.9 144.4 69.5 57.8 186.9 144.3 314.9 60.1 48.1 39.4 92.4 114.3 59.9 57.9 55.7 47.0 48.4 34.6 28.7 55.6 108.8 39.9 144.8 143.3 109.7 22.8 9.9 25.8 75.7 58.3 68.2 86.9 75.3 79.5 74.0 84.6 68.1 85.1 88.6 8.5 50.6 75.9 70.4 80.4 38.8 54.8 60.2 57.3 82.2 57.1 58.5 55.9 57.2 55.6 56.6 58.8 55.6 55.7 28.9 46.0 41.1 68.2 128.1 155.3 625.3 82.0 31.5 80.6 109.5 338.4 84.4 188.6 130.6 47.9 51.4 47.9 477.5 540.0 148.2 102.5 82.0 30.1 49.8 106.9 47.7 33.0 177.6 47.8 78.7 84.6 79.2 85.7 59.3 44.6 280.4 92.7 38.7 30.4 374.3 240.1 66.7 108.9 33.1 134.5 61.2 104.9 7.5 108.9 79.7 45.3 22.1 21.6 141.6 313.2 148.6 61.2 121.4 186.2 466.2 95.5 29.9 105.2 83.2 315.3 146.4 68.3 315.1 132.8 47.2 66.0 121.1 358.4 210.9 FAM207A "C21orf70, PRED56" ENSG00000160256 "Family with sequence similarity 207 member A" Q9NSI2 21 44940012-44976989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034178, HPA036354, HPA036559" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "CAB034178: AB_1564323, HPA036354: AB_10672242, HPA036559: " "unprognostic (1.83e-1)" "unprognostic (9.07e-2)" "unprognostic (4.99e-3)" "unprognostic (1.05e-2)" "unprognostic (1.37e-2)" "unprognostic (1.14e-3)" "prognostic unfavorable (7.04e-4)" "unprognostic (3.23e-2)" "unprognostic (4.31e-2)" "unprognostic (1.93e-2)" "unprognostic (1.84e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (7.80e-4)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (4.12e-1)" "unprognostic (5.77e-2)" 19.8 20.9 9.8 11.3 11.0 12.6 17.6 13.9 16.1 14.3 5.7 22.3 11.1 15.1 2.1 17.9 14.5 2.2 53.6 10.6 9.8 20.3 31.1 13.0 9.3 11.1 10.8 11.6 21.5 6.0 9.4 5.3 10.7 14.2 3.7 6.1 15.7 5.7 43.3 18.5 14.3 4.8 7.7 23.8 20.2 27.3 12.3 9.4 10.5 14.4 6.5 21.4 13.4 10.0 48.4 51.9 17.2 22.2 8.3 11.4 40.9 32.4 8.7 24.4 19.6 88.1 14.8 49.0 68.7 11.5 35.5 31.8 23.9 35.5 9.7 35.9 72.8 144.6 36.4 75.2 33.1 47.7 18.1 19.9 20.4 22.0 19.2 10.5 26.7 41.6 83.9 33.5 18.6 86.7 45.2 74.3 58.2 36.0 72.1 44.0 18.4 85.7 23.5 19.0 84.0 35.7 43.0 50.7 51.4 12.2 35.4 33.8 35.2 20.4 42.3 27.5 70.8 70.0 65.5 47.6 16.3 81.1 29.1 3.1 4.0 4.1 1.8 4.1 1.8 7.7 3.2 4.3 3.8 5.0 3.5 3.5 2.4 4.4 4.7 8.9 4.0 2.3 9.8 11.0 13.9 16.1 10.6 9.8 11.1 10.8 10.7 7.7 12.3 10.0 13.8 0.0 7.5 5.5 25.6 19.2 31.7 35.3 27.9 22.7 41.4 57.7 22.6 34.3 22.7 18.4 4.2 36.9 28.8 60.0 46.9 68.1 14.8 30.6 30.1 23.3 26.4 29.2 3.2 63.5 70.7 23.3 16.8 20.9 10.2 48.6 26.4 56.3 68.4 6.7 3.8 34.3 12.2 33.3 18.4 38.5 14.6 24.9 24.9 1.0 51.7 36.9 41.2 6.0 2.9 59.3 34.8 12.8 29.4 77.9 84.1 90.2 15.2 18.3 32.9 17.7 36.2 82.0 42.0 35.1 21.0 30.8 19.5 70.7 44.3 39.9 FAM221B C9orf128 ENSG00000204930 "Family with sequence similarity 221 member B" A6H8Z2 9 35816391-35828747 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 2.9;testis: 9.8" "Group enriched" "Detected in some" 12 "Early spermatids: 266.3;Late spermatids: 122.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026577 Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA026577: AB_1845810" "unprognostic (1.23e-1)" "unprognostic (5.32e-2)" "unprognostic (9.40e-2)" "unprognostic (3.59e-2)" "unprognostic (1.25e-1)" "unprognostic (9.81e-3)" "unprognostic (6.94e-2)" "unprognostic (2.44e-2)" "unprognostic (4.03e-1)" "unprognostic (2.67e-2)" "unprognostic (3.13e-3)" "unprognostic (4.22e-1)" "unprognostic (9.20e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-1)" "unprognostic (3.15e-2)" "unprognostic (1.25e-3)" 0.1 0.1 0.2 0.4 0.3 2.9 0.4 1.2 0.4 0.2 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.3 0.2 0.2 0.1 0.0 0.1 0.2 0.5 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.7 0.5 0.6 0.5 0.0 0.3 0.2 0.0 0.1 0.3 0.3 0.4 9.8 0.3 0.2 0.1 0.0 0.5 0.2 0.0 0.6 0.0 0.2 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.9 0.0 0.0 2.9 0.1 0.0 0.2 0.3 1.2 0.4 0.2 0.1 0.5 0.2 0.5 0.3 0.3 0.6 0.0 0.0 3.1 0.3 0.4 0.0 0.4 1.0 0.0 4.1 0.8 0.4 0.4 0.0 1.8 0.0 0.0 0.1 16.1 0.3 0.0 0.1 266.3 0.5 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.4 1.2 2.0 0.3 0.0 122.0 2.1 0.4 0.0 0.0 0.2 1.9 0.0 1.0 0.7 0.2 1.6 0.7 0.3 1.3 0.0 0.1 2.7 5.5 0.0 0.1 0.2 6.0 1.4 0.0 0.0 0.0 0.0 0.1 0.2 1.3 FAM229B "C6orf225, DKFZp586F0922, LOC619208" ENSG00000203778 "Family with sequence similarity 229 member B" Q4G0N7 6 112087591-112102790 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 448.1" "Group enriched" "Detected in many" 8 "Early spermatids: 3403.2;Late spermatids: 7607.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA036068 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA036068: AB_10673495" "unprognostic (1.65e-1)" "unprognostic (9.41e-2)" "unprognostic (4.29e-2)" "unprognostic (4.67e-3)" "unprognostic (3.17e-2)" "unprognostic (2.00e-2)" "unprognostic (2.71e-2)" "unprognostic (1.76e-2)" "unprognostic (5.08e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-3)" "unprognostic (4.74e-2)" "prognostic favorable (8.76e-4)" "unprognostic (3.74e-3)" "unprognostic (1.36e-1)" "unprognostic (1.80e-2)" "unprognostic (2.06e-2)" 18.2 21.7 62.1 3.6 69.4 3.7 16.9 68.5 85.4 20.7 67.9 21.1 3.5 25.8 36.4 7.2 53.4 19.1 69.9 60.5 68.7 29.2 25.0 15.3 3.5 70.0 69.7 25.9 8.6 43.6 66.1 10.6 71.3 19.2 5.4 35.4 9.0 22.6 13.6 7.7 7.4 18.4 72.8 5.2 18.7 448.1 65.2 10.9 21.1 15.3 3.3 19.0 11.3 77.1 4.0 9.9 39.9 19.5 34.3 34.0 1.9 14.9 56.6 21.0 44.0 1.7 9.4 3.1 43.0 27.7 21.9 2.5 8.4 21.7 33.4 1.0 27.7 3.7 4.1 15.7 21.3 8.1 1.8 20.7 14.3 34.8 5.9 48.6 20.9 35.2 4.9 7.8 26.0 1.0 15.1 12.9 10.4 2.9 23.2 23.3 10.0 3.2 31.3 0.6 37.0 15.5 11.9 1.3 23.9 21.4 19.1 7.4 12.0 17.5 7.4 67.1 20.2 5.8 0.3 28.6 27.7 6.8 23.5 0.1 0.0 2.1 3.0 0.0 3.9 1.8 2.6 2.4 0.4 2.6 5.6 5.1 0.2 4.6 0.2 2.5 0.3 1.9 62.1 69.4 68.5 85.4 60.5 68.7 70.0 69.7 71.3 72.8 65.2 77.1 53.7 3.2 11.4 10.4 4.7 8.4 18.8 48.6 12.0 31.3 23.6 34.7 93.9 21.5 42.1 51.5 12.5 1.5 1.9 0.3 133.1 31.7 3403.2 207.7 18.5 24.6 3.0 9.0 17.2 10.4 6.9 32.9 7.1 11.6 1.3 36.1 33.2 54.4 3.1 16.8 14.8 0.6 52.9 3.2 7.3 7607.9 72.7 6.2 24.9 6.5 2.1 83.5 4.1 12.1 35.8 6.7 0.1 90.7 5.0 11.6 0.1 93.0 409.9 36.9 59.2 26.5 32.6 663.2 51.1 5.5 8.7 0.5 4.4 64.0 0.7 12.2 FAM237A ENSG00000235118 "Family with sequence similarity 237 member A" A0A1B0GTK4 2 206642487-206649365 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in single" NA NA "unprognostic (3.02e-1)" 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.2 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.7 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.8 0.6 0.7 0.3 0.3 0.3 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 FAM50B "D6S2654E, X5L" ENSG00000145945 "Family with sequence similarity 50 member B" Q9Y247 6 3849373-3851320 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 88.3;MCF7: 27.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA064111, HPA067817" Approved Enhanced "Nucleoplasm,Cytokinetic bridge,Midbody" Yes NA "Cluster 15: NK-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Midbody" "HPA064111: AB_2685191, HPA067817: AB_2685904" "unprognostic (1.15e-1)" "unprognostic (7.76e-2)" "unprognostic (4.28e-2)" "unprognostic (4.43e-2)" "unprognostic (2.12e-3)" "unprognostic (2.69e-1)" "unprognostic (2.38e-2)" "unprognostic (7.13e-2)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (2.15e-1)" "unprognostic (2.90e-1)" "prognostic favorable (4.01e-6)" "unprognostic (1.60e-1)" "unprognostic (3.22e-1)" "unprognostic (1.34e-1)" "unprognostic (9.39e-2)" 6.9 9.1 11.7 3.7 14.3 1.8 7.0 12.3 15.1 8.3 8.5 10.2 6.6 9.7 3.9 6.6 8.8 3.7 18.0 12.5 13.6 9.8 12.9 5.3 5.1 11.7 11.1 9.3 9.2 4.2 10.4 1.7 11.5 6.4 1.4 5.5 10.2 5.8 32.1 7.1 6.5 2.8 11.2 7.1 8.1 14.0 13.0 3.9 9.8 8.8 3.5 9.7 6.3 12.6 6.6 8.7 0.1 0.0 4.9 4.7 0.4 7.6 3.7 5.1 6.5 0.0 11.7 7.0 8.0 5.5 2.0 4.9 0.0 3.0 3.8 88.3 4.6 0.0 21.1 0.0 5.2 0.0 0.1 5.2 6.0 4.0 1.1 1.6 5.1 0.0 0.0 0.0 4.6 27.5 0.0 9.8 1.9 4.0 4.1 0.0 0.0 0.0 2.5 0.0 11.8 10.3 12.4 7.7 0.4 0.0 8.4 7.8 7.2 0.0 0.9 10.1 0.0 0.0 19.7 0.0 2.7 0.6 14.1 5.7 7.9 4.4 11.3 10.8 26.7 25.0 21.8 14.6 10.5 20.8 17.7 11.2 3.3 33.8 17.7 17.3 36.0 9.0 11.7 14.3 12.3 15.1 12.5 13.6 11.7 11.1 11.5 11.2 13.0 12.6 11.4 16.0 7.0 2.6 8.3 6.4 5.7 10.2 15.4 18.1 8.7 13.5 19.8 17.2 8.3 12.9 4.2 4.2 9.3 2.3 33.2 13.5 31.5 6.8 5.0 6.7 1.2 6.7 2.5 11.1 6.9 8.0 7.1 3.3 3.8 7.5 11.0 21.6 10.1 15.2 2.6 3.5 8.2 6.8 4.7 28.8 8.4 5.6 12.4 1.0 8.7 20.9 4.1 1.0 4.6 8.5 5.1 10.9 6.9 3.3 7.4 36.9 6.8 16.0 0.0 13.0 8.4 38.3 43.9 12.5 6.7 1.0 6.1 7.8 3.8 2.1 FAM71E1 ENSG00000142530 "Family with sequence similarity 71 member E1" Q6IPT2 19 50466785-50476848 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 76.6" "Group enriched" "Detected in many" 50 "Early spermatids: 2052.1;Late spermatids: 3617.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEK 293: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048111 Approved "Nucleoli fibrillar center" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoli fibrillar center" "HPA048111: " "unprognostic (2.16e-1)" "unprognostic (2.36e-2)" "unprognostic (3.66e-2)" "unprognostic (8.65e-2)" "unprognostic (8.19e-2)" "unprognostic (7.61e-2)" "unprognostic (1.99e-1)" "unprognostic (5.45e-3)" "unprognostic (2.11e-1)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.35e-7)" "unprognostic (7.26e-2)" "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (2.37e-2)" 0.4 1.0 3.6 0.2 4.1 0.0 0.9 6.4 6.6 0.9 2.6 0.9 1.1 0.6 0.7 1.6 1.4 0.6 1.5 3.5 4.8 3.5 2.7 1.0 0.0 5.4 3.9 2.5 2.4 1.2 4.0 0.4 4.5 2.0 0.2 1.2 2.5 0.7 3.7 1.6 0.9 0.0 3.7 0.3 1.5 76.6 3.9 0.4 2.2 1.7 0.2 0.6 0.8 3.1 1.9 1.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.3 0.0 0.1 0.4 2.9 0.0 0.7 0.0 0.2 13.8 0.0 0.7 0.0 2.1 0.1 1.7 0.6 1.4 0.1 0.3 0.2 0.0 1.0 0.5 0.8 0.0 2.4 0.5 0.0 0.0 3.6 2.1 1.5 0.2 0.8 0.8 2.5 3.2 0.7 1.0 3.4 0.4 0.8 2.6 0.8 0.0 0.0 0.8 0.1 0.2 0.7 1.6 0.1 0.0 0.0 0.1 0.4 0.4 0.9 0.8 0.1 1.2 0.5 0.8 0.4 0.1 1.1 0.8 1.0 0.4 1.5 0.2 0.9 0.1 0.2 3.6 4.1 6.4 6.6 3.5 4.8 5.4 3.9 4.5 3.7 3.9 3.1 1.5 0.0 0.5 0.3 1.1 0.6 3.5 3.9 2.8 5.0 8.2 12.4 2.1 0.0 2.3 3.7 0.0 7.0 0.0 0.9 11.7 3.9 2052.1 3.8 1.9 2.0 3.0 0.4 1.7 5.4 3.6 2.2 4.6 2.0 0.0 7.4 2.2 2.4 2.0 5.0 2.5 5.3 2.0 0.0 0.4 3617.6 17.1 1.7 0.0 0.0 1.6 11.6 0.0 0.5 1.1 2.4 2.1 15.1 0.4 4.4 2.3 16.3 3.9 9.9 19.7 1.2 1.5 56.2 30.2 5.2 2.4 14.0 0.4 5.6 3.2 4.1 FAM78A "C9orf59, FLJ00024" ENSG00000126882 "Family with sequence similarity 78 member A" Q5JUQ0 9 131258076-131276510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 53.7;testis: 31.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.7;Early spermatids: 90.6;Granulosa cells: 167.2;Late spermatids: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 39.3;HEL: 38.6;HL-60: 38.7;NB-4: 60.7;THP-1: 53.5;U-937: 35.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021472, HPA023914" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA021472: AB_1848411, HPA023914: AB_1848412" "unprognostic (5.16e-2)" "prognostic favorable (3.67e-4)" "unprognostic (3.65e-2)" "unprognostic (2.07e-2)" "unprognostic (2.71e-1)" "prognostic favorable (2.00e-4)" "unprognostic (3.24e-1)" "unprognostic (5.49e-2)" "unprognostic (1.46e-2)" "unprognostic (5.83e-1)" "unprognostic (5.84e-2)" "unprognostic (6.79e-2)" "unprognostic (1.59e-3)" "unprognostic (2.61e-3)" "unprognostic (7.42e-2)" "unprognostic (2.61e-2)" "unprognostic (2.39e-1)" 2.9 2.0 3.8 13.8 5.6 21.7 1.7 3.6 6.3 1.4 1.8 2.4 2.7 1.5 0.3 1.7 1.3 3.1 26.5 5.1 3.7 1.6 1.5 6.1 24.5 5.6 4.1 1.4 1.1 1.1 1.2 5.3 4.9 1.4 1.6 4.6 2.7 0.9 53.7 1.2 8.9 1.8 4.6 21.6 3.8 31.9 5.8 21.1 1.6 20.2 14.9 3.5 1.1 5.7 0.7 0.3 2.5 5.6 1.7 0.5 39.3 0.3 0.3 0.5 0.2 0.3 0.2 17.1 0.2 0.3 0.8 0.1 16.0 0.2 0.1 4.4 1.4 38.6 0.6 0.3 0.6 38.7 1.5 0.4 0.8 0.0 0.1 0.5 22.2 10.8 13.8 4.7 0.5 6.0 1.7 60.7 2.6 0.3 0.6 4.0 2.3 23.7 0.2 0.1 1.5 2.1 2.3 0.8 2.4 0.9 1.4 53.5 0.6 2.3 2.4 1.3 0.1 3.4 1.9 9.7 0.3 35.9 0.6 0.5 9.7 17.6 9.2 12.6 7.4 14.2 8.9 10.1 6.0 15.9 11.0 9.3 9.8 3.1 9.9 2.7 9.5 8.7 3.8 5.6 3.6 6.3 5.1 3.7 5.6 4.1 4.9 4.6 5.8 5.7 3.2 0.0 1.5 0.0 15.5 0.9 0.0 0.0 0.0 55.7 0.4 0.5 17.6 0.0 0.0 1.8 0.0 1.1 19.0 0.0 0.0 0.1 90.6 0.1 0.2 6.8 0.0 3.4 5.0 0.0 37.6 3.1 0.5 0.1 1.3 167.2 6.4 0.5 25.7 0.0 1.7 0.0 0.0 21.7 10.6 120.3 5.0 14.8 1.8 15.9 15.6 0.8 30.9 1.0 0.1 0.1 0.0 3.4 12.0 0.0 0.0 0.2 0.0 1.8 0.0 0.6 6.3 2.2 1.2 0.0 0.9 1.4 17.4 1.0 0.0 0.1 FASTKD1 FLJ21901 ENSG00000138399 "FAST kinase domains 1" Q53R41 2 169528508-169573875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 91.8;Inhibitory neurons: 89.9;Oligodendrocyte precursor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043719 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043719: AB_2678635" "unprognostic (3.08e-3)" "unprognostic (1.63e-1)" "unprognostic (6.91e-3)" "unprognostic (8.03e-3)" "unprognostic (1.99e-2)" "unprognostic (3.84e-1)" "unprognostic (5.56e-3)" "unprognostic (1.15e-1)" "unprognostic (3.83e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (2.17e-1)" "unprognostic (4.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.41e-1)" "unprognostic (7.58e-2)" "unprognostic (7.62e-3)" 6.0 7.8 8.2 10.0 9.2 7.1 7.7 15.2 12.6 4.4 20.5 17.5 17.8 6.4 10.5 11.9 5.3 5.3 27.2 8.6 8.4 10.8 10.1 6.5 10.2 10.0 7.6 2.5 8.7 15.4 8.2 8.3 10.4 5.6 22.1 17.8 9.8 6.3 15.4 7.3 16.8 9.0 7.5 8.9 9.7 10.5 7.0 10.0 10.8 26.4 12.4 9.1 6.5 11.3 10.9 12.2 15.6 18.1 10.4 14.6 27.0 18.2 10.5 14.4 17.5 19.4 17.5 33.6 16.8 11.4 25.0 29.4 43.9 19.8 23.2 30.7 23.6 48.6 18.8 22.7 7.9 45.7 14.7 10.0 17.3 21.9 12.5 12.0 20.9 28.7 36.0 18.6 18.9 7.8 35.9 37.5 30.9 30.6 14.9 28.2 17.1 40.8 21.2 18.4 34.3 11.2 16.4 30.9 26.8 26.9 5.7 42.7 14.1 16.8 16.8 16.7 18.7 16.5 34.3 24.8 14.3 39.5 11.6 20.6 4.7 2.2 3.3 5.5 4.7 4.9 4.4 3.7 6.3 4.3 4.7 4.0 0.5 7.1 2.6 6.2 3.1 2.5 8.2 9.2 15.2 12.6 8.6 8.4 10.0 7.6 10.4 7.5 7.0 11.3 5.2 16.0 8.7 46.0 12.7 5.4 6.4 9.8 13.1 16.5 5.7 4.3 30.4 10.0 9.2 3.7 25.0 10.1 10.6 18.3 1.9 6.1 13.4 6.9 8.8 6.6 15.0 21.7 91.8 4.8 10.2 4.7 13.3 7.2 18.3 10.2 5.7 8.0 13.1 11.8 89.9 12.1 10.2 10.0 4.2 5.1 0.9 11.3 1.8 36.5 10.6 3.7 5.2 64.8 46.3 5.8 13.1 2.6 52.9 5.6 16.7 7.4 5.4 19.4 0.0 7.3 3.9 27.2 6.5 19.4 4.4 8.1 9.6 9.0 17.2 7.7 FEM1A ENSG00000141965 "Fem-1 homolog A" Q9BSK4 19 4791734-4801273 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "skeletal muscle: 273.6;tongue: 121.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016565, HPA063622" Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Golgi apparatus" Cytosol "HPA016565: AB_1848489, HPA063622: AB_2685063" "unprognostic (4.62e-2)" "unprognostic (1.96e-1)" "unprognostic (1.66e-1)" "unprognostic (6.75e-2)" "unprognostic (3.60e-1)" "unprognostic (2.42e-3)" "unprognostic (2.04e-1)" "unprognostic (6.74e-2)" "unprognostic (1.25e-2)" "unprognostic (9.21e-2)" "unprognostic (2.28e-3)" "unprognostic (6.25e-2)" "unprognostic (6.18e-5)" "unprognostic (3.72e-3)" "unprognostic (1.25e-1)" "unprognostic (1.91e-1)" "unprognostic (4.70e-2)" 4.3 3.7 8.0 4.0 7.8 7.5 4.4 8.1 8.0 3.2 6.8 3.8 3.7 3.0 3.6 8.4 3.4 2.7 17.8 8.2 6.1 3.8 4.4 4.2 4.7 7.9 7.5 3.5 8.5 9.6 0.9 4.2 7.3 4.9 3.3 3.0 5.9 3.3 273.6 8.5 3.3 3.9 7.1 4.3 3.9 2.4 7.8 4.8 3.5 121.2 4.6 4.1 1.0 8.5 9.2 6.2 5.7 12.4 6.2 3.6 8.3 5.4 4.4 8.5 6.0 9.7 4.1 10.4 5.4 6.7 4.6 9.3 10.1 8.9 5.5 12.4 11.6 10.1 4.9 7.4 9.4 17.0 12.4 5.3 13.6 6.6 9.4 4.0 6.2 13.9 15.1 19.3 5.9 9.3 14.3 6.2 17.7 5.7 15.0 13.1 7.4 11.0 7.7 11.6 18.5 13.1 7.1 13.2 10.4 4.3 10.2 14.5 8.7 7.7 5.6 12.1 14.4 22.3 20.0 8.8 7.9 12.1 11.1 4.7 2.8 2.8 2.5 3.2 2.1 1.9 2.0 2.3 2.6 2.5 1.7 2.0 2.4 2.6 3.0 2.6 1.5 1.8 8.0 7.8 8.1 8.0 8.2 6.1 7.9 7.5 7.3 7.1 7.8 8.5 7.9 25.6 32.8 1.6 16.6 20.1 14.9 7.7 12.5 16.8 20.8 16.4 6.5 18.6 15.5 1.8 16.7 21.2 16.1 16.7 13.7 10.3 5.3 8.7 11.6 12.3 13.1 28.6 2.7 11.8 13.8 9.2 6.1 19.1 22.8 7.5 15.4 18.7 12.3 11.8 3.2 15.5 4.1 15.4 8.7 3.5 9.0 13.1 3.6 2.8 17.2 12.1 32.0 2.5 2.3 12.4 9.4 8.2 9.9 15.5 10.9 10.1 11.3 19.8 6.6 27.1 9.3 12.7 6.2 18.3 29.5 27.1 14.3 16.8 18.0 17.7 FER1L6 C8ORFK23 ENSG00000214814 "Fer-1 like family member 6" Q2WGJ9 8 123851987-124120061 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 10.8;stomach 1: 43.1" "Group enriched" "Detected in some" 9 "Early spermatids: 15.8;Gastric mucus-secreting cells: 39.3;Intestinal goblet cells: 10.4;Late spermatids: 30.5;Pancreatic endocrine cells: 10.8" "Group enriched" "Detected in some" 6 "pancreatic cancer: 4.2;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;ASC TERT1: 1.8;BJ hTERT+: 1.2;PC-3: 1.7;U-87 MG: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054117 Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA054117: AB_2682387" "unprognostic (1.90e-1)" "unprognostic (3.08e-3)" "unprognostic (2.06e-3)" "unprognostic (3.91e-2)" "unprognostic (2.09e-1)" "unprognostic (9.49e-3)" "unprognostic (1.36e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (3.32e-2)" "unprognostic (3.23e-6)" "unprognostic (7.09e-2)" "unprognostic (8.43e-2)" "unprognostic (2.79e-3)" "unprognostic (6.39e-2)" 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.0 5.0 2.9 0.0 0.0 0.1 0.2 0.0 0.1 0.4 0.0 3.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.1 0.0 4.5 0.1 0.0 0.0 43.1 2.5 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 1.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.7 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 0.4 15.8 0.3 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 39.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.4 0.0 0.0 0.0 30.5 0.9 0.0 0.0 1.9 0.0 0.0 0.0 1.0 1.0 10.8 2.2 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.8 FGGY FLJ10986 ENSG00000172456 "FGGY carbohydrate kinase domain containing" Q96C11 1 59296638-59810647 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 77.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 191.7;Cholangiocytes: 343.1;Hepatocytes: 142.3" "Cancer enhanced" "Detected in all" "liver cancer: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 42.9;RH-30: 28.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054971, HPA075137" Approved "Nucleoplasm,Nuclear bodies" NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Nuclear bodies" "HPA054971: , HPA075137: " "unprognostic (4.15e-1)" "unprognostic (1.87e-1)" "unprognostic (2.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (2.20e-3)" "unprognostic (1.47e-3)" "unprognostic (1.80e-2)" "unprognostic (4.09e-1)" "unprognostic (2.78e-1)" "unprognostic (2.92e-1)" "unprognostic (1.47e-1)" "unprognostic (4.36e-3)" "unprognostic (7.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.70e-1)" "unprognostic (1.78e-1)" 4.2 14.6 10.5 2.0 12.8 2.3 6.6 21.8 10.2 6.3 4.5 7.1 7.1 4.7 36.5 5.5 9.9 5.4 11.3 7.4 12.1 19.1 77.1 4.7 3.3 12.9 13.4 4.8 12.0 10.5 9.7 3.0 12.9 7.8 6.7 9.6 7.5 10.3 41.8 5.7 8.1 4.2 9.3 2.8 6.1 4.2 16.5 4.1 7.7 17.1 3.6 7.0 5.2 12.7 4.8 1.4 9.2 3.9 4.7 16.6 0.8 4.1 6.8 2.3 3.4 0.0 3.8 5.4 13.0 11.0 4.1 2.0 1.6 11.9 4.9 42.9 1.1 3.8 2.9 8.6 12.3 2.3 2.4 23.2 10.2 5.0 7.9 10.0 4.6 6.0 2.7 3.4 15.3 5.2 3.0 3.2 5.8 13.0 5.3 6.5 28.3 2.1 12.9 8.8 7.2 3.2 5.6 3.3 12.0 8.0 2.8 2.3 4.7 4.0 2.6 4.7 2.8 7.5 2.9 4.6 12.9 9.2 3.8 1.5 1.3 1.4 3.0 1.3 2.7 5.1 1.4 3.8 2.2 3.6 2.7 4.3 2.2 2.9 3.4 1.1 2.8 1.8 10.5 12.8 21.8 10.2 7.4 12.1 12.9 13.4 12.9 9.3 16.5 12.7 3.7 54.5 191.7 83.2 7.9 20.9 23.8 45.2 14.2 10.1 33.1 66.9 29.9 343.1 40.4 12.9 12.5 9.3 3.7 4.2 17.6 62.6 14.0 33.2 7.5 6.9 2.4 12.2 20.4 42.5 4.5 7.6 7.1 20.4 10.1 5.3 5.3 142.3 11.4 8.4 33.7 11.3 22.4 8.8 7.6 11.4 1.8 6.7 35.6 17.8 11.2 12.2 3.1 39.2 36.0 17.7 7.7 3.0 3.4 19.1 14.9 47.9 91.2 16.4 0.0 31.4 8.9 4.6 11.5 13.5 31.5 4.5 5.1 5.9 17.1 35.5 FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" 43.4 75.2 30.4 31.0 33.3 31.4 37.3 33.5 42.0 28.9 43.9 66.8 68.2 36.9 26.1 51.1 27.9 23.7 179.0 33.9 33.1 101.8 276.4 26.4 30.0 31.8 31.0 24.9 38.1 95.0 31.1 32.1 32.1 33.5 69.0 58.8 42.0 38.4 213.4 40.3 59.1 42.0 32.4 30.1 53.6 44.4 32.7 31.3 34.6 229.3 40.4 37.5 33.7 33.0 129.2 105.6 97.9 89.0 93.9 110.0 154.9 155.7 121.1 171.6 107.1 152.2 78.0 81.1 100.3 119.9 75.0 178.4 151.7 115.8 148.4 93.5 48.9 76.3 102.2 131.4 84.1 180.2 66.7 80.2 70.7 96.6 108.0 60.2 107.2 175.8 236.3 101.7 126.9 64.3 156.6 120.1 104.5 186.2 223.6 127.4 107.2 365.7 167.4 107.6 125.4 108.4 131.1 153.3 104.0 67.2 117.1 120.9 106.5 76.6 98.9 137.0 264.0 90.3 103.7 97.3 85.7 203.5 112.6 11.9 22.8 4.9 16.1 33.3 21.0 27.2 18.8 15.1 46.7 25.1 22.3 21.1 1.3 18.3 29.1 23.1 23.8 16.7 30.4 33.3 33.5 42.0 33.9 33.1 31.8 31.0 32.1 32.4 32.7 33.0 17.1 38.5 30.2 9.4 25.0 20.0 24.6 69.5 17.1 24.7 19.9 17.5 173.5 35.8 40.0 23.9 14.6 101.6 13.7 44.0 78.2 60.4 226.0 25.4 23.5 18.6 18.0 37.7 12.7 45.0 58.7 25.5 26.5 25.4 19.0 24.9 13.6 80.4 50.7 35.3 14.9 40.6 48.8 18.5 14.4 37.4 23.9 23.9 24.9 8.4 27.9 35.0 10.3 8.0 14.4 29.4 35.7 26.7 41.3 19.0 66.1 86.0 29.2 39.1 39.5 27.7 67.9 84.7 47.1 32.1 18.6 166.1 14.9 48.4 74.2 22.8 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad diadenosine triphosphatase" P49789 3 59747277-61251459 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 94.0" "Cell type enhanced" "Detected in many" "Astrocytes: 609.8;Inhibitory neurons: 450.5;Microglial cells: 337.3;Oligodendrocyte precursor cells: 1086.7;Oligodendrocytes: 1111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "naive CD4 T-cell: 87.6" "Lineage enriched" "Detected in all" 12 "T-cells: 87.6" "Cell line enhanced" "Detected in many" "RPMI-8226: 17.5;U-266/70: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 12000 "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favorable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 5.6 24.4 13.7 6.2 18.3 8.0 9.0 13.0 17.3 5.4 94.0 6.9 6.4 3.5 6.9 5.0 6.6 9.8 15.8 19.7 16.4 24.9 9.6 4.7 7.6 18.9 17.0 6.8 13.0 18.1 7.9 3.0 18.9 5.3 5.8 7.6 8.5 4.7 10.6 8.1 5.3 4.7 15.0 5.0 8.6 5.5 15.9 12.1 11.7 7.2 5.3 6.7 4.2 19.8 0.1 0.0 1.4 0.0 0.6 0.1 2.5 0.1 0.2 0.1 0.0 2.7 4.2 4.0 0.7 0.1 3.0 0.0 12.7 3.2 0.0 2.2 5.0 3.3 2.0 6.4 3.3 8.7 0.1 9.1 5.2 0.2 6.9 0.3 0.0 3.7 2.5 11.9 0.2 3.6 15.2 6.7 1.2 12.2 0.9 11.3 0.0 17.5 15.3 2.0 2.9 4.3 1.5 9.9 10.1 5.3 0.4 0.2 0.0 1.7 0.4 0.1 2.4 34.6 11.3 0.0 4.0 0.1 1.9 6.8 4.6 0.5 2.2 2.9 1.4 4.1 17.2 1.8 5.7 3.1 87.6 15.6 0.8 7.2 1.3 5.8 20.5 11.9 13.7 18.3 13.0 17.3 19.7 16.4 18.9 17.0 18.9 15.0 15.9 19.8 4.1 6.4 10.6 609.8 19.7 7.6 20.7 30.0 46.7 12.6 41.2 31.2 10.0 38.6 17.5 27.6 58.4 42.0 12.4 6.9 78.2 19.1 45.8 14.6 7.9 7.0 7.7 17.7 276.6 4.7 8.5 10.1 18.3 19.0 5.7 25.7 14.6 23.4 20.9 30.3 450.5 12.9 22.4 10.2 7.1 163.0 19.3 12.9 12.4 337.3 8.6 19.7 6.2 1086.7 1111.0 9.7 15.0 9.8 23.8 12.0 20.7 126.6 12.4 20.7 0.0 10.7 6.2 19.1 7.5 33.7 11.2 32.7 11.5 23.0 20.1 18.8 FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 1421.4;ovary: 535.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1077.5;Extravillous trophoblasts: 585.9;Granulosa cells: 851.4;Leydig cells: 567.0;Peritubular cells: 1049.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.7" "Group enriched" "Detected in many" 6 "granulocytes: 5.7;T-cells: 2.7" "Cell line enhanced" "Detected in many" "LHCN-M2: 534.6;RPTEC TERT1: 489.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" NA Yes 14000 "Cluster 18: Basophils - Vesicular transport" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Focal adhesion sites" "CAB008368: AB_591383, HPA005922: AB_1078860, HPA006028: AB_1078858" "unprognostic (1.04e-1)" "unprognostic (1.63e-3)" "unprognostic (3.30e-1)" "unprognostic (3.42e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (2.80e-2)" "unprognostic (1.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.42e-2)" "unprognostic (3.34e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (6.42e-5)" "unprognostic (2.06e-1)" "unprognostic (3.49e-1)" "unprognostic (9.92e-3)" "unprognostic (4.73e-2)" 68.3 70.2 10.4 28.9 13.2 17.0 65.4 7.6 18.2 101.9 15.0 75.2 48.5 105.1 33.8 55.4 55.8 81.5 1421.4 18.9 7.4 55.2 22.1 17.5 17.2 6.7 7.2 535.4 9.1 8.2 29.3 79.3 7.0 88.8 56.8 8.5 45.3 63.8 67.5 44.2 50.4 91.5 7.5 20.1 94.9 50.9 7.9 22.8 41.3 118.6 13.9 105.5 47.2 12.2 156.8 36.1 20.9 0.8 65.2 81.7 196.4 289.3 75.9 182.2 216.7 65.6 237.6 0.4 23.7 353.6 223.8 47.7 31.4 262.4 204.2 6.5 23.9 108.7 42.9 49.0 257.6 0.4 23.5 171.7 142.2 286.0 188.1 360.8 374.4 18.0 29.0 8.9 534.6 5.6 25.8 1.0 44.1 108.3 113.2 0.4 31.6 4.3 489.8 108.4 1.0 6.9 109.2 48.1 76.9 20.5 60.7 3.9 183.1 130.4 134.1 146.4 236.0 3.3 0.6 0.7 208.1 0.6 138.5 5.7 0.4 0.4 1.1 0.2 0.7 0.6 0.9 2.0 0.4 0.5 0.7 1.5 2.2 0.7 0.2 0.6 2.7 1.5 10.4 13.2 7.6 18.2 18.9 7.4 6.7 7.2 7.0 7.5 7.9 12.2 15.7 9.6 5.1 0.7 1.0 468.5 1077.5 342.5 389.9 9.5 59.8 126.2 362.1 15.7 91.0 29.5 2.1 220.4 1.7 212.6 3.9 100.7 5.7 44.8 40.4 27.4 58.2 63.5 46.3 117.9 585.9 96.1 186.1 32.5 10.2 851.4 17.2 9.2 25.3 0.0 4.9 169.8 73.2 0.6 31.8 17.3 567.0 10.4 23.2 25.3 2.7 1.6 0.0 0.5 1.6 234.5 258.2 1049.0 6.7 198.2 51.7 28.1 19.1 13.0 216.9 60.6 171.0 9.1 17.7 124.5 296.9 178.7 7.7 193.5 55.8 536.2 FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297714-36780055 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 172.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 87.6;Excitatory neurons: 132.2;Granulosa cells: 84.9;Inhibitory neurons: 186.5;Oligodendrocyte precursor cells: 114.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 72.3;HDLM-2: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021827: AB_1848571, HPA024696: AB_1848573" "unprognostic (8.46e-2)" "unprognostic (8.76e-2)" "unprognostic (6.34e-2)" "unprognostic (3.44e-1)" "unprognostic (8.96e-2)" "unprognostic (8.30e-2)" "unprognostic (4.11e-4)" "unprognostic (2.73e-2)" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (2.16e-3)" "unprognostic (4.55e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (4.10e-2)" "unprognostic (3.00e-3)" "unprognostic (1.20e-1)" 3.4 32.1 13.2 2.4 14.3 0.1 6.1 8.7 17.7 5.6 13.9 14.5 1.6 3.0 42.2 9.4 11.2 7.2 172.8 13.8 12.3 23.2 1.4 1.5 1.3 37.9 15.1 6.9 2.1 1.0 10.5 1.3 36.8 27.9 3.4 36.1 11.3 62.8 49.5 6.5 5.5 10.1 11.5 1.3 3.2 4.1 8.5 2.4 3.6 20.5 4.0 14.6 5.2 13.5 15.5 5.4 34.3 8.2 0.2 0.0 2.6 34.1 72.3 6.7 6.5 0.0 24.5 2.8 8.9 16.3 19.2 19.5 11.4 14.8 4.0 80.1 4.0 0.0 1.0 0.1 0.4 0.0 1.1 4.5 7.1 3.6 1.5 36.6 0.2 0.0 0.0 0.2 8.0 0.0 0.1 0.2 7.5 0.0 4.9 0.0 0.0 18.9 32.5 17.0 19.0 44.6 7.4 0.1 4.6 3.0 0.2 0.1 39.6 21.3 1.6 0.9 29.5 31.8 0.0 0.0 23.8 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 14.3 8.7 17.7 13.8 12.3 37.9 15.1 36.8 11.5 8.5 13.5 0.4 0.0 0.0 104.5 0.0 3.2 0.9 8.9 14.8 6.5 2.3 11.4 38.0 0.0 2.7 12.9 87.6 0.1 0.0 0.2 3.9 1.3 1.7 10.2 1.7 0.6 0.0 0.4 132.2 0.9 11.3 7.9 1.1 0.6 0.0 84.9 0.0 0.0 0.2 0.0 186.5 0.2 6.1 0.0 0.6 0.4 0.0 0.3 10.6 11.2 0.0 7.3 0.0 114.1 3.4 3.3 0.1 0.4 0.0 0.6 0.0 7.9 15.3 33.6 0.0 11.2 6.3 2.2 2.8 1.6 0.6 0.4 0.4 29.9 0.3 0.3 FITM2 "C20orf142, dJ881L22.2, FIT2" ENSG00000197296 "Fat storage inducing transmembrane protein 2" Q8N6M3 20 44302840-44311202 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 67.4" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.92e-2)" "unprognostic (7.61e-2)" "unprognostic (2.27e-2)" "unprognostic (2.10e-3)" "unprognostic (1.02e-1)" "unprognostic (3.57e-3)" "unprognostic (1.63e-2)" "unprognostic (3.90e-2)" "unprognostic (8.43e-2)" "unprognostic (5.19e-2)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "prognostic favorable (8.98e-12)" "unprognostic (2.07e-1)" "unprognostic (2.54e-1)" "unprognostic (3.38e-3)" "unprognostic (2.49e-3)" 11.4 11.1 4.8 2.9 5.0 1.2 7.0 5.7 6.3 4.2 5.9 5.2 4.3 4.0 8.7 3.3 3.7 3.2 67.4 4.8 5.9 7.9 6.4 4.1 2.2 6.9 5.9 4.6 7.4 13.6 5.2 1.9 7.4 6.4 6.0 6.7 6.5 4.4 9.2 5.7 3.9 5.3 4.2 2.6 4.6 3.8 5.4 1.7 6.3 16.8 2.6 4.5 3.1 4.7 7.2 10.9 4.5 6.6 31.4 12.8 4.6 11.5 8.4 8.9 4.9 13.5 5.1 4.9 6.5 13.0 14.3 15.8 5.7 7.7 9.6 1.4 2.7 1.6 6.5 22.9 6.6 3.1 4.0 9.7 17.2 6.2 4.7 4.9 6.4 3.1 2.7 14.2 9.1 22.4 1.2 3.4 1.1 10.8 13.9 1.9 8.4 4.9 5.1 6.7 2.7 3.2 24.4 13.5 10.3 2.0 16.5 2.4 7.9 28.2 12.6 16.6 6.8 5.2 14.4 1.3 12.6 4.9 14.4 0.7 1.0 0.6 1.1 1.0 1.2 0.6 1.2 0.9 1.0 0.6 2.0 1.6 0.4 1.4 0.8 0.6 1.2 0.9 4.8 5.0 5.7 6.3 4.8 5.9 6.9 5.9 7.4 4.2 5.4 4.7 2.8 6.4 9.7 1.3 3.6 6.9 3.5 2.8 1.2 6.4 5.0 3.4 153.9 11.5 4.3 5.5 6.2 2.0 1.0 5.1 1.9 5.2 4.6 2.2 5.0 4.4 9.1 0.8 2.3 8.6 3.5 9.4 4.1 2.1 0.0 4.4 8.2 14.1 3.4 6.7 2.1 4.8 0.0 3.8 2.2 1.2 7.8 1.7 7.2 1.0 2.3 6.6 2.1 4.0 0.9 5.7 4.1 7.5 3.1 3.1 5.9 6.2 4.0 5.9 0.0 5.6 6.3 9.1 6.0 2.7 8.1 1.5 2.1 16.3 9.2 2.2 FKBP3 "FKBP-25, FKBP25" ENSG00000100442 "FKBP prolyl isomerase 3" Q00688 14 45115599-45135319 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 424.4;tongue: 372.0" "Cell type enhanced" "Detected in all" "Late spermatids: 377.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol NA NA 1300000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB012232: , CAB012520: AB_873554, HPA000864: AB_1078873" "unprognostic (7.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (9.72e-2)" "unprognostic (1.25e-1)" "unprognostic (9.82e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-1)" "unprognostic (5.04e-3)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (6.92e-3)" "unprognostic (1.00e-1)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" 40.9 46.8 100.3 35.8 102.3 38.4 50.0 110.1 122.1 38.1 91.8 49.4 44.7 31.4 64.8 54.7 31.4 29.8 109.5 101.9 100.6 66.5 69.7 27.6 53.7 100.7 99.3 35.3 32.8 55.5 56.6 46.9 100.1 57.7 49.1 82.3 37.1 37.9 424.4 38.3 47.8 39.2 99.8 39.9 38.0 52.9 101.4 59.6 40.1 372.0 57.7 43.3 38.6 105.8 161.0 175.3 249.0 132.4 109.0 117.8 98.3 96.2 110.3 149.3 163.5 154.8 134.1 85.1 98.9 110.0 84.1 130.0 188.4 124.8 211.7 123.7 111.0 69.8 138.8 202.6 107.1 122.2 72.8 112.0 127.5 87.2 80.1 136.8 198.0 131.9 102.9 62.1 179.9 196.9 197.5 163.0 126.7 178.3 164.5 187.0 183.7 102.9 242.2 183.7 151.2 59.2 154.8 94.5 156.0 186.4 222.6 89.9 128.7 113.0 195.6 59.9 75.1 104.0 198.8 132.5 68.3 83.0 108.1 23.4 22.4 22.1 18.7 27.3 22.8 29.7 25.0 25.7 33.3 21.8 23.4 26.7 3.6 24.2 29.4 43.0 30.8 20.2 100.3 102.3 110.1 122.1 101.9 100.6 100.7 99.3 100.1 99.8 101.4 105.8 48.3 41.7 46.6 25.8 45.3 47.8 94.4 205.5 45.5 79.3 39.9 46.7 202.5 48.6 101.4 93.8 10.4 320.9 51.2 56.4 252.4 131.1 212.7 55.0 83.3 58.5 56.1 50.9 49.7 73.0 135.4 70.0 36.7 68.1 53.7 75.6 38.2 91.1 131.1 40.4 44.5 71.2 124.1 39.9 43.0 377.4 80.8 53.7 69.4 17.8 110.7 80.7 50.4 21.1 34.3 88.4 53.7 97.8 58.0 76.4 91.8 220.1 73.5 67.4 105.2 71.3 118.5 154.0 111.2 65.0 47.9 165.0 48.8 84.1 96.1 77.6 FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735615-82751196 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 79.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 90.1;Proximal tubular cells: 167.2;Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 34.3;Hep G2: 66.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Approved Mitochondria NA NA 180000 "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA059151: AB_2683931, HPA061358: AB_2684490" "unprognostic (4.74e-2)" "unprognostic (9.19e-2)" "unprognostic (4.22e-2)" "prognostic favorable (1.10e-4)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (6.45e-2)" "unprognostic (9.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.61e-1)" "prognostic favorable (2.40e-4)" "unprognostic (6.66e-2)" "prognostic favorable (1.39e-6)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (4.77e-1)" "unprognostic (1.22e-2)" 14.4 47.3 47.4 2.9 64.3 12.0 8.4 64.4 56.6 10.4 36.8 15.5 22.4 9.4 7.0 4.6 12.5 6.9 47.5 46.5 54.3 49.6 48.1 7.8 2.4 63.3 56.8 22.3 18.1 21.9 22.4 5.3 62.7 12.5 9.5 13.8 28.5 12.1 23.5 5.3 14.5 6.6 49.4 4.6 17.4 5.2 55.6 1.0 10.2 10.9 2.3 8.8 7.9 79.8 1.3 16.1 4.4 23.2 6.9 5.7 2.9 2.9 2.2 5.4 2.7 21.0 3.3 0.2 3.9 2.6 4.5 0.6 34.3 2.5 2.0 1.0 2.4 12.5 12.9 66.2 18.8 0.3 10.1 4.9 9.0 2.1 0.0 5.7 10.6 1.0 22.4 0.6 1.1 1.8 0.2 0.2 2.9 7.6 13.0 2.1 0.3 0.1 11.5 4.5 7.0 22.7 5.3 1.2 15.8 3.8 15.4 4.5 2.5 0.4 1.6 5.6 4.3 1.2 0.3 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 64.3 64.4 56.6 46.5 54.3 63.3 56.8 62.7 49.4 55.6 79.8 3.9 3.2 2.0 8.8 1.9 1.5 3.7 1.5 14.8 41.9 4.5 3.7 5.8 4.3 2.5 31.3 47.9 11.7 2.6 5.7 90.1 3.2 0.2 11.6 3.0 5.2 5.4 49.2 10.2 1.2 2.6 8.6 47.9 25.9 1.3 6.9 4.2 5.4 8.2 32.0 13.0 10.4 6.1 1.0 3.4 0.4 5.3 5.7 12.4 5.6 1.2 36.2 1.0 6.0 17.1 1.7 7.3 3.0 9.1 3.9 28.2 167.2 2.5 72.9 0.0 6.1 9.8 0.8 4.1 12.8 1.8 8.3 3.1 18.6 9.5 3.5 FNDC5 FRCP2 ENSG00000160097 "Fibronectin type III domain containing 5" Q8NAU1 1 32862268-32872482 "Predicted membrane proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 323.1;tongue: 478.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 71.3;Cardiomyocytes: 64.9;Early spermatids: 28.1;Granulosa cells: 38.6;Muller glia cells: 44.1" "Group enriched" "Detected in many" 7 "glioma: 4.2;liver cancer: 10.0;testis cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "RH-30: 48.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051290 Enhanced "Intracellular and membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "HPA051290: AB_2681422" "unprognostic (4.36e-2)" "unprognostic (9.08e-3)" "unprognostic (7.62e-4)" "unprognostic (1.03e-2)" "unprognostic (3.77e-2)" "unprognostic (6.26e-2)" "unprognostic (5.68e-2)" "unprognostic (2.76e-2)" "unprognostic (1.45e-2)" "unprognostic (1.83e-1)" "unprognostic (3.15e-3)" "unprognostic (1.63e-1)" "unprognostic (9.07e-2)" "unprognostic (7.07e-3)" "unprognostic (1.13e-1)" "unprognostic (3.37e-3)" "unprognostic (1.33e-2)" 1.3 12.8 10.5 0.1 5.8 0.2 0.8 21.6 10.0 1.4 47.6 1.3 0.8 3.3 2.4 11.6 4.1 1.8 42.2 6.7 16.8 0.7 18.4 1.1 0.2 10.5 14.7 4.6 0.5 10.4 5.2 0.5 7.6 3.6 0.5 8.0 25.5 1.0 323.1 0.4 1.3 2.0 5.3 0.2 5.2 2.7 29.6 0.6 1.2 478.4 0.1 1.2 0.8 3.3 0.0 0.1 1.1 0.4 0.0 1.2 0.2 0.5 0.1 0.7 0.1 0.9 0.3 0.2 0.8 0.4 0.2 0.1 4.7 0.1 0.1 0.1 0.3 0.1 0.4 0.2 0.0 0.2 0.0 1.8 0.0 0.3 0.0 0.6 0.0 0.2 0.9 0.1 0.8 0.1 0.1 0.1 1.4 0.0 0.1 0.6 48.2 0.3 0.0 0.1 6.9 1.1 0.5 0.0 0.0 0.5 0.2 0.1 0.2 0.1 0.8 2.2 0.4 0.2 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 5.8 21.6 10.0 6.7 16.8 10.5 14.7 7.6 5.3 29.6 3.3 1.1 0.0 0.0 7.5 0.0 0.1 0.2 0.0 0.0 71.3 0.6 0.5 64.9 0.0 0.0 1.8 4.2 0.0 0.0 0.0 1.9 0.0 28.1 0.3 4.6 1.4 0.0 0.0 10.3 0.0 0.0 14.5 0.0 0.5 0.0 38.6 0.7 2.0 0.9 0.0 15.8 0.1 0.0 0.0 0.5 5.9 5.3 0.8 0.0 5.6 0.0 44.1 0.0 3.0 0.7 0.1 0.0 5.7 0.0 0.2 0.1 0.2 0.0 7.4 0.0 12.9 1.7 0.5 1.0 0.0 0.0 0.3 0.2 0.5 0.5 0.1 FOXRED1 H17 ENSG00000110074 "FAD dependent oxidoreductase domain containing 1" Q96CU9 11 126269055-126278131 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039620, HPA046192" Uncertain Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA039620: AB_2676602, HPA046192: AB_2679580" "prognostic unfavorable (7.36e-4)" "unprognostic (4.62e-2)" "unprognostic (2.71e-1)" "unprognostic (3.47e-3)" "unprognostic (1.76e-1)" "unprognostic (1.84e-1)" "unprognostic (9.59e-2)" "unprognostic (1.43e-1)" "unprognostic (8.14e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.01e-6)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" 8.1 13.8 13.6 5.9 14.6 12.1 7.6 15.3 16.6 5.8 17.1 12.0 10.4 6.7 6.4 9.2 7.5 5.6 21.2 15.0 14.7 14.7 37.4 5.3 10.4 15.3 14.3 4.8 7.8 9.7 8.1 7.1 15.3 6.9 12.9 3.7 7.3 6.8 17.8 7.5 8.6 7.9 14.7 11.1 10.9 8.7 15.8 11.5 6.1 29.4 10.6 7.1 6.0 14.8 23.5 26.6 19.5 24.3 14.2 6.8 26.1 11.6 14.9 22.1 22.1 40.0 24.1 38.2 32.3 9.8 28.7 38.5 51.7 31.5 13.8 20.4 14.3 79.7 16.7 48.2 18.8 19.7 16.4 6.3 12.1 14.9 26.5 6.0 24.7 40.2 46.6 20.6 18.7 32.7 23.1 35.3 16.0 61.8 45.2 37.0 34.1 45.2 20.5 11.9 25.0 21.5 23.8 35.7 13.1 12.2 85.9 33.4 9.0 13.1 10.7 23.8 19.4 12.2 19.0 31.9 16.2 66.5 18.7 1.6 10.1 5.9 6.7 13.4 7.0 7.1 5.3 8.9 12.1 6.2 7.4 6.7 2.0 9.9 9.9 16.8 7.6 8.1 13.6 14.6 15.3 16.6 15.0 14.7 15.3 14.3 15.3 14.7 15.8 14.8 6.1 9.6 11.5 19.6 13.5 3.6 6.2 14.9 8.0 24.8 7.3 7.0 21.7 10.0 10.7 3.7 27.1 27.7 12.2 12.6 7.9 13.6 4.2 7.4 8.7 7.6 13.1 14.9 24.7 13.8 24.1 9.8 17.9 7.8 9.5 17.8 10.0 28.2 20.4 13.5 27.1 12.6 8.2 7.1 5.1 7.2 5.6 8.0 8.8 4.7 7.1 18.6 9.2 14.1 16.1 10.7 5.9 11.3 24.4 4.6 8.9 21.0 6.7 32.2 6.6 8.9 9.6 24.5 24.0 11.0 5.7 21.1 8.9 25.0 14.9 4.8 FRMD5 MGC14161 ENSG00000171877 "FERM domain containing 5" Q7Z6J6 15 43870761-44195271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 38.7;heart muscle: 46.6;retina: 20.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 375.2;Inhibitory neurons: 646.2;Oligodendrocyte precursor cells: 298.6;Oligodendrocytes: 2000.1" "Cancer enhanced" "Detected in many" "glioma: 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 26.4;U-251 MG: 21.8;WM-115: 61.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (9.54e-2)" "unprognostic (2.16e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (7.26e-7)" "unprognostic (3.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" "unprognostic (5.00e-3)" "prognostic unfavorable (5.89e-4)" "unprognostic (7.01e-2)" "unprognostic (2.92e-4)" "unprognostic (1.21e-1)" "unprognostic (7.31e-2)" "unprognostic (1.18e-1)" "unprognostic (3.31e-1)" 0.2 8.3 14.8 0.5 24.2 0.8 0.4 18.0 20.5 0.3 4.5 1.4 0.2 0.1 0.4 0.3 1.0 0.4 46.6 15.1 18.9 0.3 0.0 0.1 0.3 22.1 21.2 0.3 0.2 0.8 2.0 0.0 20.6 0.5 0.8 20.0 1.1 0.3 0.0 0.3 0.5 0.2 15.6 0.3 1.3 3.4 19.5 0.0 0.3 0.0 0.0 0.4 0.4 38.7 6.6 3.5 2.3 1.3 2.6 0.2 0.4 1.4 2.1 3.9 7.4 11.2 6.6 0.5 1.3 0.9 10.6 7.3 3.3 7.0 3.3 0.4 3.7 1.0 3.1 4.4 0.3 0.1 0.4 0.0 0.7 10.6 20.8 7.6 26.4 5.7 0.2 0.7 4.1 0.6 1.0 0.1 1.9 21.3 3.8 0.1 4.7 0.0 3.6 2.3 14.3 4.8 0.8 0.1 15.0 1.8 0.2 0.2 1.0 7.1 13.4 1.8 21.8 0.5 2.0 0.8 10.4 0.4 61.2 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 14.8 24.2 18.0 20.5 15.1 18.9 22.1 21.2 20.6 15.6 19.5 38.7 0.0 0.0 0.0 134.8 0.0 0.4 0.0 0.8 0.6 11.4 0.1 0.3 14.8 0.0 0.1 0.0 2.1 0.0 0.0 0.3 0.0 2.8 14.7 0.3 0.1 0.2 1.2 0.0 375.2 6.0 0.0 1.1 7.1 0.1 0.0 3.9 0.0 0.0 0.1 0.0 646.2 0.8 0.0 0.0 0.3 5.2 0.3 0.0 0.0 14.0 0.0 17.5 0.0 298.6 2000.1 8.6 0.3 0.0 0.3 0.4 0.0 1.0 0.1 4.4 0.0 0.1 0.7 6.6 3.9 0.2 0.0 0.0 0.1 0.0 1.3 0.1 FRMPD1 "FRMD2, KIAA0967" ENSG00000070601 "FERM and PDZ domain containing 1" Q5SYB0 9 37650954-37746904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 68.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 47.8;Cone photoreceptor cells: 152.2;Inhibitory neurons: 24.3;Rod photoreceptor cells: 79.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Group enriched" "Detected in many" 4 "granulocytes: 3.2;NK-cells: 1.3" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042934 Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA042934: AB_10960422" "unprognostic (6.41e-2)" "unprognostic (6.74e-3)" "unprognostic (1.25e-1)" "unprognostic (1.48e-3)" "unprognostic (4.04e-1)" "unprognostic (7.26e-2)" "unprognostic (1.45e-1)" "unprognostic (1.06e-1)" "unprognostic (2.03e-1)" "unprognostic (2.53e-3)" "unprognostic (2.63e-3)" "unprognostic (3.94e-2)" "unprognostic (1.12e-3)" "unprognostic (7.80e-2)" "unprognostic (4.41e-2)" "unprognostic (2.13e-2)" "unprognostic (5.91e-2)" 0.4 0.5 3.1 0.8 3.8 2.9 0.9 2.9 4.1 0.3 0.4 0.5 0.7 1.0 0.6 1.6 0.8 1.6 0.7 2.6 2.9 0.5 0.5 0.7 1.3 3.1 4.8 0.3 0.9 0.7 0.8 0.4 2.6 0.5 0.5 68.9 4.1 0.5 4.2 6.4 1.1 0.4 2.2 0.4 0.6 9.4 5.5 0.2 1.0 1.2 1.1 0.5 0.1 4.5 0.2 0.3 1.2 0.1 0.0 0.0 1.5 0.5 0.0 0.1 0.1 0.6 0.5 0.3 0.2 0.3 0.5 0.9 0.9 0.5 0.3 0.4 0.3 0.1 0.5 0.3 0.0 0.0 0.2 0.6 0.0 0.5 0.2 0.6 0.0 0.9 0.5 0.2 0.2 0.3 0.1 0.2 0.7 0.1 0.6 0.6 1.0 0.1 0.0 0.9 2.5 1.7 0.0 1.6 0.8 0.4 0.8 0.3 0.0 0.3 0.5 0.5 0.4 0.4 0.7 0.6 0.4 0.3 0.4 3.2 0.4 0.3 0.2 0.3 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 1.0 1.3 0.4 0.3 0.2 0.1 3.1 3.8 2.9 4.1 2.6 2.9 3.1 4.8 2.6 2.2 5.5 4.5 0.2 3.2 10.5 11.1 0.3 0.1 0.3 0.0 0.0 47.8 0.5 0.3 1.1 4.3 1.8 0.0 152.2 0.2 0.0 0.4 0.0 0.1 4.8 0.2 0.1 1.4 0.0 0.0 3.7 0.2 0.5 0.8 0.0 0.4 5.1 0.2 0.7 0.8 0.1 1.7 24.3 0.3 0.0 1.3 2.1 1.3 0.9 0.8 0.0 1.0 0.3 9.0 0.0 13.6 6.7 0.1 0.1 0.4 0.1 0.2 0.0 0.0 1.5 79.8 0.0 0.8 0.2 0.4 1.7 0.0 0.4 0.7 1.0 0.1 0.1 0.3 FRMPD4 "KIAA0316, PDZD10, PDZK10" ENSG00000169933 "FERM and PDZ domain containing 4" Q14CM0 X 11822423-12724523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.6;parathyroid gland: 3.7;retina: 4.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 941.1;Inhibitory neurons: 772.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.0;U-2197: 2.1;U-266/70: 3.3;U-266/84: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.05e-1)" "unprognostic (3.70e-2)" "unprognostic (3.50e-2)" "unprognostic (2.68e-3)" "unprognostic (8.84e-2)" "unprognostic (1.05e-2)" "unprognostic (3.56e-2)" "unprognostic (2.09e-2)" "unprognostic (1.62e-2)" "unprognostic (6.32e-2)" "unprognostic (3.39e-1)" "unprognostic (1.62e-1)" "unprognostic (1.96e-1)" "unprognostic (2.25e-1)" 0.0 0.0 4.6 0.0 4.5 0.0 0.0 0.1 7.6 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.7 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 3.7 0.1 0.0 0.0 0.2 0.1 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.2 3.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.5 0.1 7.6 4.3 0.3 0.0 0.8 0.0 0.0 1.7 3.5 0.2 0.0 0.0 50.3 0.0 0.1 0.0 0.0 0.0 3.2 0.1 0.0 3.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 941.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 168.2 772.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 11.2 0.0 0.5 0.0 39.7 11.7 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 10.2 0.0 0.0 FUNDC1 MGC51029 ENSG00000069509 "FUN14 domain containing 1" Q8IVP5 X 44523639-44542859 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038773 Uncertain NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA038773: AB_10670789" "unprognostic (1.04e-1)" "unprognostic (3.91e-2)" "unprognostic (1.91e-1)" "unprognostic (3.11e-2)" "unprognostic (4.93e-1)" "unprognostic (1.72e-2)" "unprognostic (3.40e-3)" "unprognostic (1.88e-3)" "unprognostic (6.40e-2)" "unprognostic (2.85e-3)" "unprognostic (6.63e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-1)" "unprognostic (2.49e-2)" "prognostic favorable (8.35e-4)" "unprognostic (6.67e-3)" "prognostic favorable (2.58e-4)" 11.5 18.4 30.5 9.5 31.3 11.3 20.4 35.9 37.8 14.4 30.3 12.7 12.5 13.4 22.4 13.1 15.3 15.8 37.6 30.5 34.2 25.2 13.0 10.5 17.8 36.0 31.7 19.0 10.2 28.2 14.8 11.5 34.5 16.3 13.5 34.2 49.2 11.5 17.9 16.2 8.0 12.4 32.0 12.8 29.7 14.4 33.3 20.0 16.8 24.9 16.3 15.5 12.0 32.1 39.4 33.1 36.5 22.4 15.8 21.8 20.8 19.4 29.4 38.2 41.7 41.3 32.2 29.0 19.1 26.6 83.5 21.0 60.4 36.7 46.2 32.2 67.6 32.5 41.5 32.3 23.4 35.3 103.3 22.1 35.3 55.1 27.4 36.6 23.8 30.9 34.9 18.0 45.8 41.6 32.9 42.6 43.3 33.6 38.4 20.3 37.1 21.5 39.1 28.0 20.0 31.6 59.3 32.5 37.7 66.0 65.4 0.1 14.0 23.5 34.1 28.0 21.6 14.0 25.2 34.6 31.1 13.8 31.3 7.5 6.3 10.9 7.3 6.3 9.8 10.8 10.1 11.5 11.6 6.6 11.5 9.0 6.8 11.5 4.6 23.8 10.7 5.5 30.5 31.3 35.9 37.8 30.5 34.2 36.0 31.7 34.5 32.0 33.3 32.1 15.2 19.2 10.8 5.2 12.5 14.8 20.1 67.3 18.2 21.9 18.6 21.2 41.6 27.1 34.1 25.8 6.2 35.3 13.0 14.0 115.4 33.6 1.7 27.1 20.9 15.8 10.2 12.0 5.3 36.8 29.4 20.2 16.8 23.1 7.6 36.4 20.3 14.8 37.5 21.9 6.4 13.8 42.7 14.5 7.2 5.7 23.0 13.6 14.2 6.5 13.1 62.9 17.5 6.6 6.8 34.6 26.0 21.8 14.3 17.5 14.5 50.7 26.4 16.1 13.1 12.9 19.8 19.9 45.4 20.7 16.3 26.5 12.7 35.5 17.1 26.0 FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.1;Hepatocytes: 651.7;Leydig cells: 430.3;Muller glia cells: 343.4;Skeletal myocytes: 188.7;Smooth muscle cells: 205.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Cell line enhanced" "Detected in some" "ASC diff: 46.7;ASC TERT1: 13.5;HSkMC: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" 141.4 26.1 496.5 9.6 528.9 2.2 125.1 506.1 637.3 291.9 616.5 168.3 14.3 173.3 62.1 70.7 187.3 56.3 557.7 487.5 503.4 28.6 558.7 85.8 6.6 568.0 515.0 144.7 19.2 3.8 39.8 29.3 494.8 116.0 25.6 35.9 37.2 73.5 1381.3 48.3 67.2 104.5 511.1 20.8 72.6 12.1 560.2 8.2 38.0 838.7 6.7 80.0 194.9 498.6 1.1 0.0 0.0 0.2 46.7 13.5 1.3 5.7 0.1 0.0 0.0 0.0 0.3 3.8 1.5 0.0 0.1 1.0 1.1 0.7 0.0 3.4 1.3 0.7 0.0 1.9 5.2 0.3 0.4 19.3 0.0 0.1 0.5 0.5 0.2 0.1 1.0 3.7 0.1 0.0 0.1 0.8 0.2 2.8 0.6 0.0 0.2 1.1 0.0 0.0 0.3 0.2 0.7 0.2 1.8 0.3 0.2 6.1 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.4 0.9 0.6 7.7 1.6 0.3 0.0 1.3 0.7 0.8 11.0 3.6 1.5 0.3 6.9 0.7 0.9 0.5 2.1 0.8 0.6 6.9 0.6 496.5 528.9 506.1 637.3 487.5 503.4 568.0 515.0 494.8 511.1 560.2 498.6 46.1 0.0 0.0 44.4 15.8 29.4 3.7 2.7 8.0 1.8 4.4 18.0 0.3 11.5 0.8 25.8 4.2 1.2 9.5 42.2 0.0 0.1 1.9 2.2 47.4 13.3 0.0 8.4 3.7 4.9 1.6 225.1 2.0 1.2 0.0 0.1 36.0 651.7 4.4 0.0 0.4 0.8 2.0 14.4 49.0 12.0 430.3 5.3 53.4 2.8 1.0 343.4 1.0 1.5 0.5 1.1 5.3 128.2 2.5 3.3 0.4 0.2 12.6 8.6 118.3 188.7 205.7 10.7 21.7 3.0 27.3 2.9 18.8 0.1 0.7 2.5 FYCO1 "FLJ13335, ZFYVE7" ENSG00000163820 "FYVE and coiled-coil domain autophagy adaptor 1" Q9BQS8 3 45917899-45995824 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 263.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035526, HPA057966" Uncertain Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA035526: AB_10672867, HPA057966: AB_2683567" "unprognostic (2.45e-1)" "unprognostic (6.62e-2)" "unprognostic (6.97e-3)" "unprognostic (1.14e-3)" "unprognostic (7.65e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-2)" "unprognostic (4.53e-3)" "unprognostic (5.85e-2)" "unprognostic (8.85e-2)" "unprognostic (2.36e-1)" "unprognostic (2.98e-1)" "prognostic favorable (3.33e-11)" "unprognostic (2.90e-1)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (6.99e-2)" 16.7 13.0 10.5 9.7 12.0 6.5 13.4 9.6 9.4 23.1 11.3 42.0 8.0 25.6 10.3 21.3 15.4 18.7 66.8 8.6 10.3 10.7 10.8 14.7 8.6 15.5 10.8 23.1 12.7 20.3 7.6 8.2 14.8 19.3 10.7 33.0 14.9 22.9 263.3 19.3 14.4 28.2 15.1 10.2 20.4 3.3 11.9 10.5 16.5 104.6 8.2 39.6 16.9 15.1 10.8 10.3 3.0 13.0 27.9 21.8 4.9 10.2 23.7 13.1 14.6 5.6 9.3 7.9 5.6 14.2 12.7 7.9 8.5 17.0 15.7 3.3 9.0 11.4 8.7 6.3 19.0 8.8 7.9 24.3 16.7 21.1 20.5 20.3 26.7 13.4 7.4 11.3 9.5 6.7 9.0 5.5 4.5 8.8 9.8 3.1 8.3 4.4 15.9 37.2 2.2 3.4 6.4 20.0 17.6 4.4 9.7 5.7 20.8 5.0 5.9 17.0 5.7 6.4 4.4 2.7 17.2 11.1 9.6 0.7 0.5 0.3 2.0 0.5 2.7 0.2 1.2 2.1 0.2 0.2 0.5 0.7 0.4 1.5 0.3 1.3 1.2 0.7 10.5 12.0 9.6 9.4 8.6 10.3 15.5 10.8 14.8 15.1 11.9 15.1 9.5 28.9 13.7 12.4 4.8 4.1 4.8 5.6 3.4 11.2 8.5 4.8 89.3 8.6 13.0 16.5 35.5 4.3 8.7 6.8 3.9 8.8 0.1 6.4 8.9 9.3 9.6 6.9 0.8 8.3 2.2 14.0 12.8 11.2 2.5 14.9 11.4 9.2 4.1 0.0 0.8 7.6 2.0 5.8 4.6 1.6 12.8 5.1 10.6 10.3 4.0 20.0 6.2 8.0 21.2 11.0 2.5 17.7 3.0 17.3 8.7 6.2 18.6 37.1 6.6 20.8 12.8 2.3 0.8 8.4 4.1 2.9 12.7 6.1 6.2 7.9 GAL3ST3 GAL3ST2 ENSG00000175229 "Galactose-3-O-sulfotransferase 3" Q96A11 11 66040765-66049161 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.7;thyroid gland: 17.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.9;Cardiomyocytes: 3.6;Cone photoreceptor cells: 10.4;Excitatory neurons: 3.7;Horizontal cells: 5.0;Inhibitory neurons: 4.7;Oligodendrocyte precursor cells: 7.5;Rod photoreceptor cells: 15.4" "Group enriched" "Detected in many" 5 "glioma: 4.7;ovarian cancer: 5.5;thyroid cancer: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NTERA-2: 6.5;SH-SY5Y: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" "prognostic unfavorable (6.53e-6)" "unprognostic (1.24e-1)" "unprognostic (3.30e-1)" "unprognostic (1.57e-2)" "unprognostic (2.62e-1)" "unprognostic (6.08e-2)" "unprognostic (2.01e-3)" "unprognostic (7.26e-2)" "unprognostic (2.07e-2)" "unprognostic (1.40e-1)" "unprognostic (5.29e-1)" 0.0 0.0 5.3 0.0 7.7 0.0 0.0 4.8 5.7 2.9 0.1 0.0 0.0 3.9 0.1 0.0 2.6 0.0 7.1 4.8 2.1 5.3 0.0 0.0 0.0 2.0 2.6 0.2 0.6 0.3 4.1 0.0 1.6 0.8 0.0 5.7 0.0 1.6 0.3 0.1 0.0 2.8 1.5 0.0 0.0 2.1 2.8 0.0 17.1 0.3 0.0 0.0 0.3 3.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.7 4.8 5.7 4.8 2.1 2.0 2.6 1.6 1.5 2.8 3.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 3.6 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 7.5 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 15.4 0.0 0.0 0.3 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GALT ENSG00000213930 "Galactose-1-phosphate uridylyltransferase" P07902 9 34638133-34651035 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Nucleotidyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 50.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004868, HPA005729" Enhanced Approved Cytosol NA NA 260000 "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA004868: AB_1079130, HPA005729: AB_1079131" "unprognostic (2.38e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-3)" "unprognostic (1.54e-1)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.13e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-2)" "prognostic favorable (3.11e-5)" "unprognostic (9.68e-2)" "prognostic favorable (6.25e-6)" "unprognostic (7.90e-2)" "unprognostic (2.74e-1)" "unprognostic (3.56e-1)" "unprognostic (7.75e-2)" 6.7 14.0 5.3 6.7 5.9 8.1 6.3 5.5 6.5 6.9 4.6 8.5 18.3 6.9 5.3 5.3 7.8 6.8 10.4 5.2 6.3 10.0 50.0 6.6 12.0 5.5 5.7 8.2 7.5 13.0 6.1 9.2 5.3 6.4 6.7 6.3 12.3 7.5 10.2 15.2 16.5 4.0 4.5 9.7 8.1 2.4 6.1 7.8 8.2 7.6 7.7 5.3 6.1 4.7 5.5 7.5 6.8 2.4 9.0 9.2 7.8 4.2 12.1 4.3 5.1 9.5 4.8 6.1 4.2 5.2 1.6 2.9 1.3 11.8 0.8 9.7 4.8 2.5 14.7 9.8 8.7 1.4 2.9 12.6 7.4 2.7 3.6 9.3 10.6 8.3 2.3 6.4 7.3 5.1 5.4 10.3 2.3 6.7 1.3 8.4 5.9 3.3 12.5 7.8 1.6 5.7 5.0 9.8 5.4 5.0 9.2 8.2 1.6 1.7 3.4 3.4 0.0 3.9 2.4 1.3 4.1 4.4 10.8 16.5 23.7 11.7 15.4 21.5 21.3 24.8 25.2 21.1 21.5 13.2 15.3 14.8 4.6 29.0 20.4 18.2 30.0 17.6 5.3 5.9 5.5 6.5 5.2 6.3 5.5 5.7 5.3 4.5 6.1 4.7 12.6 6.4 21.2 10.7 19.0 21.7 13.4 19.3 19.4 44.0 10.5 12.1 25.7 14.3 15.4 16.5 47.9 72.5 13.9 17.3 29.4 18.3 7.6 7.8 11.8 14.6 16.3 13.7 9.1 7.3 36.3 18.3 9.2 8.0 20.3 24.7 23.6 69.9 24.1 47.1 12.5 17.0 26.4 15.5 8.7 36.8 18.3 12.4 21.4 5.6 15.9 18.7 34.0 6.0 3.7 6.9 37.5 13.9 10.7 4.7 67.1 46.3 11.1 38.5 6.6 11.2 12.2 4.8 6.6 8.6 20.2 59.1 25.5 27.4 20.4 9.2 GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 615.1;skeletal muscle: 1234.9;tongue: 466.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 718.3;Proximal tubular cells: 417.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 173.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 176.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved NA NA 420000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051806: AB_2681619" "unprognostic (3.25e-1)" "unprognostic (7.74e-3)" "unprognostic (3.22e-2)" "unprognostic (6.32e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.41e-2)" "unprognostic (7.10e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-2)" 14.0 26.6 69.4 4.5 74.5 8.8 15.6 68.6 79.1 16.5 53.4 10.9 3.2 10.0 141.9 23.0 14.7 9.9 98.1 67.3 67.1 72.0 615.1 8.1 7.7 71.8 68.3 22.8 229.8 37.8 37.4 4.9 70.4 36.5 2.2 15.0 42.6 17.5 1234.9 32.8 6.4 4.6 68.8 10.7 31.8 55.0 76.1 24.8 22.2 466.4 4.3 12.9 15.3 94.5 21.6 24.1 25.2 56.9 30.9 37.3 34.3 25.2 41.2 31.8 28.7 54.8 15.1 11.3 17.2 30.0 3.8 9.1 39.8 15.5 8.5 81.5 46.2 34.9 20.3 176.7 18.2 0.7 11.5 41.8 5.5 33.8 0.1 44.0 6.9 43.0 50.6 26.6 52.6 22.1 103.9 12.0 28.6 10.7 75.4 103.1 22.3 81.4 38.1 19.5 8.4 58.5 1.9 14.3 32.0 16.1 65.3 48.1 12.2 34.6 35.6 1.9 11.6 119.0 24.8 19.5 32.2 46.1 40.7 3.7 2.5 15.3 18.8 3.4 27.3 22.0 26.3 23.8 11.2 32.3 40.6 30.8 1.5 18.2 6.1 47.3 15.8 14.9 69.4 74.5 68.6 79.1 67.3 67.1 71.8 68.3 70.4 68.8 76.1 94.5 9.2 0.0 7.2 5.5 18.0 58.9 42.1 57.8 116.7 41.0 60.3 99.9 99.3 127.2 12.9 16.5 56.3 35.7 15.4 0.8 92.0 39.9 5.2 6.5 7.4 9.2 7.2 35.8 7.4 33.6 41.2 30.9 10.2 4.0 4.5 43.3 18.9 718.3 81.7 18.5 10.1 1.5 6.1 29.5 13.3 16.0 83.9 13.9 32.0 3.7 4.7 57.3 10.3 4.0 36.7 13.5 0.1 139.5 12.5 24.1 0.1 417.4 6.1 61.7 32.9 77.8 47.1 4.3 22.6 42.1 42.9 12.0 19.7 31.1 3.3 23.2 GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813055 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 39.7" "Group enriched" "Detected in some" 4 "Astrocytes: 39.8;Excitatory neurons: 114.9;Inhibitory neurons: 141.9;Oligodendrocytes: 83.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Hep G2: 43.2;JURKAT: 24.0;Karpas-707: 85.2;SCLC-21H: 24.8;U-266/84: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: AB_2683850" "unprognostic (5.48e-3)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-5)" "prognostic favorable (6.13e-4)" "unprognostic (5.85e-2)" "unprognostic (4.22e-2)" "unprognostic (7.94e-2)" "unprognostic (3.58e-2)" 0.4 0.8 2.1 0.3 1.9 0.1 0.8 4.5 5.4 0.9 0.0 0.7 1.8 0.8 0.0 0.7 1.2 1.6 3.5 0.7 2.2 5.4 39.7 1.0 1.0 6.2 7.5 2.0 9.6 0.1 2.5 0.4 6.3 1.0 0.4 2.2 1.5 0.6 4.6 0.8 1.6 0.3 3.3 1.3 2.6 0.8 6.1 8.2 0.8 1.8 0.7 1.0 0.7 6.1 0.0 0.1 1.7 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.7 0.4 0.2 0.0 43.2 0.5 0.1 0.3 0.1 0.1 0.0 0.2 0.3 0.0 24.0 1.6 85.2 0.0 0.4 0.3 0.1 0.3 2.4 0.0 0.9 0.5 4.4 0.0 1.1 24.8 1.3 0.0 0.0 0.5 0.2 0.1 0.0 1.8 0.0 0.4 1.1 0.0 1.1 30.7 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 1.9 4.5 5.4 0.7 2.2 6.2 7.5 6.3 3.3 6.1 6.1 0.1 0.0 0.0 39.8 0.4 0.1 0.4 0.1 0.6 1.9 0.4 0.1 12.7 10.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.3 1.3 0.1 0.4 0.0 0.0 114.9 3.3 0.0 1.0 3.1 0.7 0.0 0.2 0.7 22.9 0.0 0.0 141.9 0.6 0.0 0.0 0.0 5.4 0.6 0.0 0.0 9.4 0.2 0.2 0.0 18.6 83.9 1.6 1.4 0.0 0.5 0.1 0.1 3.2 4.0 1.2 0.0 0.3 0.8 0.4 1.1 0.6 0.0 0.0 0.4 0.1 0.9 0.3 GAS8 "DRC4, GAS11" ENSG00000141013 "Growth arrest specific 8" O95995 16 90019629-90044975 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 198.3;Late spermatids: 277.8;Respiratory ciliated cells: 82.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041311, HPA048238" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" Cytosol "Plasma membrane" "HPA041311: AB_2677402, HPA048238: AB_2680324" "unprognostic (2.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.73e-1)" "unprognostic (3.91e-1)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (1.16e-1)" "unprognostic (4.47e-1)" "prognostic favorable (7.67e-4)" "unprognostic (3.06e-2)" "prognostic favorable (1.09e-7)" "unprognostic (1.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.19e-2)" 5.2 10.3 9.5 2.8 9.7 1.4 6.3 10.0 14.3 7.8 12.3 7.7 2.6 6.5 10.1 8.4 18.9 6.1 15.4 9.5 9.9 13.8 5.5 7.1 2.8 10.3 10.0 8.9 10.5 16.3 14.1 2.1 10.1 7.3 3.0 5.0 11.4 8.6 15.1 4.5 3.9 4.4 10.3 3.4 8.2 16.8 10.9 2.5 12.5 10.0 2.0 6.3 5.8 10.2 17.9 14.5 1.8 8.5 7.8 6.2 14.3 3.6 8.8 13.9 4.1 14.1 13.0 1.0 9.1 7.1 8.4 17.8 5.9 9.9 3.3 0.0 10.7 3.7 9.0 16.2 8.7 2.2 2.8 7.9 6.0 10.4 4.7 6.3 8.3 5.8 14.3 2.1 6.1 41.9 2.5 9.9 11.6 11.3 7.4 0.7 15.7 1.0 17.4 8.5 14.6 10.7 18.4 9.7 21.0 1.6 19.6 8.4 6.2 8.6 10.3 4.7 8.3 3.4 5.4 0.0 21.3 2.7 15.1 1.7 1.2 1.4 0.7 2.0 0.7 0.4 1.0 1.4 1.7 0.8 0.8 0.7 1.5 0.0 1.3 1.9 1.6 0.8 9.5 9.7 10.0 14.3 9.5 9.9 10.3 10.0 10.1 10.3 10.9 10.2 5.9 22.4 11.3 20.5 3.1 1.1 4.7 7.0 5.7 11.9 14.1 10.8 7.9 25.8 13.4 22.0 20.9 3.0 0.7 5.9 13.7 17.1 198.3 45.5 7.1 5.8 6.0 3.0 27.5 10.9 3.6 5.5 12.2 10.0 2.5 16.1 7.1 4.8 4.1 26.9 24.6 6.3 8.2 0.8 1.4 277.8 14.0 2.3 5.4 1.9 1.3 12.4 0.0 13.0 6.0 10.0 4.6 7.5 1.1 5.8 5.3 30.9 82.3 28.0 6.6 6.7 9.5 28.7 11.9 7.2 2.6 1.6 1.6 25.2 5.3 5.8 GATD3B ENSG00000280071 "Glutamine amidotransferase like class 1 domain containing 3B" A0A0B4J2D5 21 5079294-5128413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal tubular cells: 17.6;Ductal cells: 6.9;Hofbauer cells: 8.0;monocytes: 7.8;Proximal tubular cells: 31.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA018517 Uncertain Approved Centrosome,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Centrosome "HPA018517: AB_2669899" "unprognostic (4.87e-2)" "unprognostic (2.69e-3)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (2.96e-1)" "unprognostic (6.47e-2)" "unprognostic (1.43e-2)" "unprognostic (2.39e-2)" "unprognostic (7.65e-2)" "unprognostic (1.71e-2)" "unprognostic (1.15e-2)" "unprognostic (3.33e-2)" "unprognostic (6.67e-4)" "unprognostic (1.88e-2)" "unprognostic (6.80e-2)" "unprognostic (4.25e-1)" "unprognostic (2.84e-2)" 53.8 77.8 82.0 34.9 87.3 31.7 48.6 88.9 90.2 40.9 76.0 55.1 71.8 36.9 27.5 59.4 44.4 41.2 195.5 78.2 87.4 141.7 239.9 34.5 53.8 89.0 86.3 66.6 52.7 61.9 54.8 40.2 90.2 43.9 57.5 32.2 60.1 33.4 208.0 40.6 51.3 32.4 83.9 48.2 50.1 33.0 89.9 35.9 55.1 225.6 28.1 40.0 41.1 85.5 55.8 52.7 57.1 98.7 42.8 38.3 23.7 0.0 4.5 1.9 2.9 7.0 54.8 2.6 61.9 62.9 51.7 38.8 77.2 34.7 1.1 36.8 32.8 217.2 60.1 47.6 41.7 94.8 39.7 80.4 69.6 28.3 57.1 39.5 64.4 66.1 86.6 51.2 34.9 118.5 94.4 103.6 110.9 150.0 80.5 190.1 43.1 223.3 72.4 49.8 48.5 96.4 76.7 138.9 52.0 28.4 146.2 131.4 19.7 27.7 39.0 2.5 33.7 80.7 79.2 37.6 64.9 192.0 20.7 87.3 110.4 60.4 102.2 123.5 101.4 153.3 129.7 107.0 147.7 167.1 124.6 95.2 21.7 136.1 167.7 96.3 145.3 190.3 82.0 87.3 88.9 90.2 78.2 87.4 89.0 86.3 90.2 83.9 89.9 85.5 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.0 0.0 2.9 1.4 0.0 17.6 6.9 0.0 1.1 1.9 0.7 0.0 0.0 0.0 5.0 3.2 0.3 0.0 2.0 0.0 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 7.8 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.7 0.0 0.0 31.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.4 0.7 1.9 0.0 0.0 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 140.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Hepatocytes: 66.1;Proximal tubular cells: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 22: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548, HPA063924: " "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 6.6 15.7 25.1 3.2 24.8 14.1 6.5 26.2 33.3 6.3 22.5 7.3 4.9 7.8 3.0 17.0 6.0 5.0 43.4 26.1 25.0 13.0 53.3 5.6 2.8 25.9 27.4 9.0 140.2 6.0 9.7 2.7 27.8 22.8 4.9 2.2 13.3 6.8 19.5 8.1 5.4 4.2 24.4 1.5 13.2 10.3 27.9 4.3 16.0 19.1 3.1 7.1 7.0 24.6 18.7 4.7 11.9 68.2 24.0 19.4 8.4 25.9 26.9 19.2 16.3 10.5 2.1 5.8 11.8 11.7 11.3 10.6 11.9 18.3 4.3 2.6 21.9 12.9 15.0 42.5 39.0 23.0 16.4 22.8 10.9 12.7 27.7 6.2 16.0 23.0 33.2 6.6 9.2 16.2 24.3 42.3 5.0 28.8 19.0 25.2 2.5 34.4 24.6 14.3 24.5 16.7 20.0 32.3 13.9 4.2 25.8 11.1 11.8 19.3 10.6 12.9 9.2 21.9 11.5 12.1 13.3 21.1 20.5 0.1 0.6 0.4 0.7 0.7 0.3 0.1 1.6 0.5 1.3 0.0 3.5 1.4 0.3 1.3 0.4 1.3 1.7 1.4 25.1 24.8 26.2 33.3 26.1 25.0 25.9 27.4 27.8 24.4 27.9 24.6 3.5 6.4 15.4 9.8 2.8 7.8 18.5 11.2 12.5 8.9 18.6 17.4 54.6 11.5 9.4 11.0 4.2 15.7 0.7 13.1 80.3 7.2 4.1 9.9 8.1 5.5 2.4 22.7 5.0 10.3 19.6 9.8 15.3 16.7 8.9 17.6 5.0 66.1 4.7 8.4 4.7 32.3 8.2 2.9 1.3 7.7 3.7 2.1 21.4 1.0 1.0 25.1 1.0 6.6 4.1 5.4 8.7 9.8 2.0 19.1 8.6 163.8 6.4 2.2 6.6 4.8 30.1 12.6 33.2 19.6 6.0 27.8 3.0 27.8 24.0 14.4 GCDH ACAD5 ENSG00000105607 "Glutaryl-CoA dehydrogenase" Q92947 19 12891160-12914207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 115.5;Proximal tubular cells: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043252, HPA048492" Enhanced Supported Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA043252: AB_2678390, HPA048492: AB_2680418" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" "unprognostic (6.79e-3)" "unprognostic (8.07e-3)" "unprognostic (8.20e-3)" "unprognostic (3.14e-2)" "prognostic favorable (7.28e-5)" "prognostic favorable (3.35e-4)" "unprognostic (1.62e-1)" "unprognostic (3.03e-2)" "unprognostic (7.50e-3)" "unprognostic (7.46e-2)" "prognostic favorable (6.79e-8)" "unprognostic (7.09e-3)" "unprognostic (3.42e-1)" "unprognostic (5.32e-2)" "unprognostic (1.59e-1)" 16.8 17.8 20.2 11.2 22.4 13.0 15.6 22.1 23.3 10.2 21.8 13.2 11.8 12.6 8.6 14.0 15.2 8.4 29.3 19.2 19.4 24.5 89.1 9.3 16.8 20.7 20.9 16.8 15.5 11.5 10.6 5.4 21.0 13.6 8.5 5.5 20.0 11.5 30.5 10.1 13.0 8.2 19.9 12.8 18.6 4.5 20.9 17.8 11.9 27.1 11.9 14.9 9.9 22.7 22.9 14.1 15.0 27.5 21.4 9.8 13.8 17.2 11.1 21.6 15.7 26.9 10.8 33.0 31.9 10.5 10.8 15.6 20.8 16.4 10.6 28.6 22.8 21.0 24.6 33.1 24.8 43.7 18.8 13.8 19.9 15.3 16.1 8.8 18.1 44.4 51.8 11.4 10.7 28.9 51.7 41.7 16.7 22.0 36.1 48.2 15.3 68.9 12.6 12.1 32.3 18.9 22.8 22.6 16.7 9.6 17.8 29.3 13.3 18.0 12.9 29.9 18.2 59.5 32.2 34.6 11.0 50.7 15.4 13.9 13.9 8.5 18.8 12.1 18.8 18.1 23.2 21.0 24.0 19.5 30.9 23.8 3.1 38.8 9.8 14.7 21.4 20.0 20.2 22.4 22.1 23.3 19.2 19.4 20.7 20.9 21.0 19.9 20.9 22.7 6.0 3.2 5.3 25.5 21.2 7.9 14.5 13.3 11.4 14.2 17.3 10.8 10.0 22.8 8.6 11.0 25.0 16.2 17.2 11.6 52.8 14.0 2.6 7.7 10.0 7.3 15.6 60.4 7.1 11.2 21.5 10.2 12.8 10.9 7.0 19.5 13.6 115.5 21.5 8.4 7.4 13.8 16.2 14.4 5.0 1.8 13.1 9.9 17.8 5.6 20.7 18.6 18.6 14.6 15.1 10.2 9.7 12.8 25.4 11.3 17.4 147.8 7.2 12.3 0.0 13.7 9.8 8.3 7.4 13.4 5.3 16.3 20.9 33.0 20.6 12.1 GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2 (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial ciliated cells: 79.1;Glandular and luminal cells: 105.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 44.2;Hep G2: 19.7;SK-MEL-30: 17.1;SuSa: 21.4" "Region enriched" "Detected in all" 4 "basal ganglia: 61.1" "Low region specificity" "Detected in all" HPA026776 Approved Approved "Golgi apparatus" No No 750000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA026776: AB_1849573" "unprognostic (2.47e-1)" "unprognostic (6.87e-3)" "unprognostic (3.12e-1)" "unprognostic (1.42e-2)" "unprognostic (9.31e-2)" "unprognostic (2.51e-1)" "unprognostic (4.11e-2)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (6.28e-4)" "unprognostic (3.96e-2)" "unprognostic (1.58e-3)" "unprognostic (6.54e-2)" "unprognostic (6.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" 0.6 0.3 0.7 1.0 0.6 0.3 10.1 2.5 1.1 4.2 4.5 3.6 5.2 1.4 0.2 1.4 0.8 1.5 6.6 0.8 1.1 5.7 5.1 3.9 1.8 1.2 1.0 0.3 1.3 0.4 1.4 2.6 1.4 13.5 2.0 0.3 4.2 0.3 0.7 1.4 5.8 1.6 0.9 1.5 5.9 2.5 0.9 0.5 1.2 1.8 2.4 1.0 0.7 1.0 6.3 4.9 1.5 4.8 0.0 0.0 9.6 0.0 4.1 1.1 0.5 11.0 5.2 3.5 44.2 0.0 3.2 0.3 0.4 5.1 2.9 3.1 1.8 0.5 2.6 19.7 0.0 1.7 4.7 0.0 0.0 0.5 0.0 2.4 9.1 0.0 0.4 0.0 0.4 0.0 0.0 4.0 4.4 0.0 3.6 0.2 3.8 6.0 16.0 2.9 4.0 1.2 0.0 14.4 17.1 21.4 0.3 0.8 6.4 0.8 0.5 0.0 5.0 0.1 0.0 2.4 0.8 0.3 2.3 1.9 1.1 0.5 0.1 0.8 0.0 0.7 0.1 0.1 0.8 0.4 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.3 0.7 0.6 2.5 1.1 0.8 1.1 1.2 1.0 1.4 0.9 0.9 1.0 1.4 76.9 32.4 1.0 9.5 4.6 6.6 15.5 9.6 5.1 30.5 16.1 18.4 2.8 28.6 7.3 0.0 27.9 6.4 15.5 11.7 2.9 4.3 79.1 5.5 11.0 2.4 25.9 0.7 24.7 2.1 2.0 16.8 105.5 2.5 0.0 12.8 32.0 15.8 3.3 11.8 5.6 6.1 7.7 9.4 8.2 0.3 7.8 49.8 52.5 11.1 2.4 0.0 18.6 1.1 12.0 11.9 0.0 1.0 16.6 44.3 13.4 27.9 0.6 0.0 0.7 2.2 6.2 27.6 11.2 1.7 10.9 3.1 0.0 16.3 8.1 GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 553.4;Extravillous trophoblasts: 1476.4;Proximal tubular cells: 655.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" 28.7 20.1 58.9 6.9 66.5 6.3 24.2 62.9 113.8 18.2 50.8 16.0 7.2 17.5 68.9 15.5 19.8 11.7 38.1 55.8 60.9 78.2 118.9 10.8 6.7 60.1 66.0 18.4 19.7 31.0 14.3 26.0 61.1 18.7 13.0 15.6 15.6 16.7 59.3 10.1 9.5 11.8 61.7 6.3 17.5 7.4 63.7 10.4 96.4 63.6 9.3 18.3 15.2 67.8 63.6 28.3 82.4 37.0 40.4 30.9 175.5 35.9 26.4 43.3 20.6 37.0 57.2 17.2 32.3 15.9 31.9 33.3 64.5 36.5 71.6 4.7 86.7 21.8 34.9 114.6 45.7 70.3 24.1 32.0 47.8 26.8 53.7 13.0 22.3 45.1 86.3 3.4 42.9 67.7 45.9 138.8 113.0 49.6 57.5 72.7 44.1 25.5 98.4 56.4 43.7 45.3 53.3 32.9 70.8 63.9 48.3 33.2 19.8 27.6 49.3 44.0 37.8 14.7 31.8 102.1 18.2 41.3 22.6 3.6 1.3 1.3 2.8 2.1 4.6 3.5 2.6 4.0 3.9 2.5 4.4 5.9 1.7 7.0 1.7 10.8 2.2 2.4 58.9 66.5 62.9 113.8 55.8 60.9 60.1 66.0 61.1 61.7 63.7 67.8 31.1 3.2 5.9 16.3 24.8 29.1 94.6 73.6 52.3 43.7 97.9 115.6 12.9 44.3 31.4 80.9 37.5 553.4 13.8 15.3 295.4 70.0 32.4 34.8 128.3 31.9 26.4 71.1 12.6 42.5 1476.4 61.6 31.1 55.2 36.3 38.5 33.2 352.0 118.8 38.7 11.9 34.3 67.1 19.7 34.6 19.5 140.8 18.8 85.4 4.7 17.7 215.8 19.6 19.6 35.2 42.3 17.8 141.1 51.7 123.9 13.7 655.9 20.0 45.7 32.9 46.2 50.2 20.7 77.3 78.4 27.1 228.8 16.3 114.5 49.4 69.8 GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: AB_2675354, HPA069871: " "unprognostic (2.58e-3)" "unprognostic (7.04e-2)" "unprognostic (8.54e-3)" "unprognostic (1.98e-1)" "unprognostic (4.49e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.33e-5)" "unprognostic (9.55e-2)" "unprognostic (4.15e-1)" "unprognostic (8.52e-3)" "unprognostic (9.82e-2)" 9.6 18.1 9.7 10.2 10.5 15.0 14.1 10.2 14.5 10.7 16.1 13.9 9.3 11.1 17.4 11.9 23.4 9.0 33.3 10.8 10.7 23.3 34.0 9.0 12.2 9.5 9.1 11.4 10.0 30.4 10.7 13.5 10.0 13.0 15.8 16.8 13.4 11.2 30.6 11.3 10.8 10.8 9.4 8.5 17.9 15.8 10.2 17.2 13.1 38.5 15.5 12.9 7.0 11.1 39.5 34.3 27.2 52.2 20.3 27.1 28.2 41.5 24.7 41.5 44.1 36.4 24.9 39.7 44.9 21.9 65.7 32.1 55.0 59.6 54.8 34.8 35.5 22.9 31.7 27.0 27.1 23.6 26.0 32.1 26.3 33.6 40.5 29.8 30.3 39.4 40.7 32.9 48.5 23.3 32.1 15.1 11.4 14.8 29.7 41.1 43.5 49.3 32.0 24.7 46.6 24.8 46.3 38.1 44.3 30.1 33.0 44.0 24.0 16.2 27.8 20.5 27.2 19.0 38.3 40.1 24.1 34.2 24.6 22.8 6.9 9.2 6.7 7.2 6.6 8.3 5.5 7.5 6.7 7.2 7.5 7.3 3.5 16.0 11.8 4.4 7.0 5.2 9.7 10.5 10.2 14.5 10.8 10.7 9.5 9.1 10.0 9.4 10.2 11.1 6.4 12.8 12.9 19.9 8.5 6.0 7.1 13.0 8.6 9.1 7.7 6.9 11.0 7.2 12.5 7.3 6.2 20.1 7.5 8.9 21.5 9.5 11.5 42.4 9.2 6.4 5.4 17.9 35.7 5.3 15.9 6.3 15.3 13.7 2.5 10.4 5.3 22.4 9.9 16.8 34.1 9.7 30.5 8.5 2.4 2.6 7.2 6.8 8.8 13.1 17.9 13.0 7.2 34.2 29.1 9.8 9.9 7.5 11.4 4.6 8.5 11.2 61.5 9.6 0.0 5.6 7.8 15.2 11.7 10.0 7.0 16.0 7.3 11.1 10.0 7.5 GHITM "DERP2, HSPC282, My021, PTD010, TMBIM5" ENSG00000165678 "Growth hormone inducible transmembrane protein" Q9H3K2 10 84139509-84153568 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1114.2;Late spermatids: 2559.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016464, HPA061664" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA016464: AB_1849656, HPA061664: AB_2684579" "unprognostic (6.26e-3)" "unprognostic (1.85e-1)" "unprognostic (2.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (5.71e-2)" "unprognostic (4.56e-2)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (8.14e-2)" "unprognostic (5.71e-2)" "prognostic favorable (2.32e-10)" "unprognostic (2.46e-2)" "unprognostic (2.09e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" 113.9 179.5 124.3 87.0 133.3 110.6 93.8 138.6 147.7 73.1 150.6 171.2 163.5 76.8 86.1 114.4 71.4 68.9 365.3 136.1 146.1 300.7 271.1 74.1 87.3 136.6 128.1 72.7 77.7 197.3 88.8 70.3 138.5 80.6 166.4 144.3 94.4 84.2 369.3 79.7 137.1 85.7 125.4 73.8 123.1 115.7 137.5 86.5 105.9 456.6 103.3 92.3 76.5 123.1 228.2 230.8 97.1 223.5 162.6 143.3 171.6 153.3 267.4 193.7 180.2 283.1 183.8 178.9 167.7 203.2 170.9 199.9 208.4 200.0 185.9 179.8 157.4 127.7 227.3 281.0 306.5 402.0 200.0 162.7 384.1 200.4 577.8 201.8 169.9 150.5 299.9 324.3 180.4 197.4 143.6 318.9 98.3 184.8 203.2 128.3 89.4 270.5 271.4 179.2 79.4 92.4 154.7 134.1 325.1 111.2 273.7 254.2 145.3 94.0 126.5 138.5 251.1 227.9 265.7 199.9 246.8 364.4 67.1 293.7 284.9 276.5 173.9 304.7 194.2 211.0 178.9 186.0 279.9 177.9 166.6 178.8 223.7 206.7 281.3 145.3 235.3 578.0 124.3 133.3 138.6 147.7 136.1 146.1 136.6 128.1 138.5 125.4 137.5 123.1 94.1 96.1 87.6 23.2 138.0 170.3 185.1 440.9 87.0 135.9 102.2 71.8 689.3 140.2 235.8 158.2 70.9 260.4 134.0 376.0 579.2 295.3 1114.2 58.7 68.6 120.7 125.6 242.9 33.6 232.3 234.9 119.6 107.6 67.1 102.0 79.3 88.5 326.1 267.7 101.0 34.5 206.0 443.5 156.2 169.2 2559.1 110.3 153.0 163.7 16.9 228.3 269.0 114.4 14.6 24.3 223.3 276.3 136.9 167.3 180.1 343.7 802.9 173.4 159.9 144.7 114.5 219.8 263.1 153.2 150.4 170.3 386.0 141.6 158.4 281.4 212.9 GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 84.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 510.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.7;MCF7: 1.3;SuSa: 1.8;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 410000 "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: AB_2684018" "unprognostic (5.04e-2)" "unprognostic (2.57e-2)" "unprognostic (5.15e-5)" "unprognostic (3.21e-3)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (2.07e-4)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.30e-2)" "unprognostic (3.15e-1)" "unprognostic (2.14e-2)" "unprognostic (9.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (3.80e-3)" "unprognostic (1.37e-1)" 18.5 2.3 18.1 1.6 51.1 0.7 9.7 35.0 28.6 1.8 0.0 3.5 0.2 0.5 0.5 0.5 1.2 3.4 5.0 15.5 31.2 0.4 0.1 8.7 0.2 47.6 48.9 0.5 0.5 0.4 0.6 3.9 56.4 2.4 6.4 1.3 1.4 0.7 1.0 5.0 0.6 0.6 26.0 2.9 2.1 0.2 41.7 0.1 0.8 0.9 0.2 1.5 1.5 84.8 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 1.0 0.0 1.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.3 2.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 18.1 51.1 35.0 28.6 15.5 31.2 47.6 48.9 56.4 26.0 41.7 84.8 40.1 0.0 2.6 2.0 0.0 6.2 0.0 0.3 0.0 9.2 0.2 0.3 8.4 0.0 0.1 0.0 0.0 5.2 0.0 47.0 0.0 0.0 0.0 0.0 0.1 3.7 1.2 0.0 7.4 0.0 0.6 7.9 4.6 0.2 0.0 4.5 0.0 0.2 4.9 0.0 17.2 1.7 0.0 14.9 9.5 0.0 0.3 16.1 3.6 42.2 0.0 0.3 0.0 2.0 510.8 0.1 28.6 0.0 0.0 0.1 0.0 0.1 0.9 0.8 0.0 4.7 9.8 0.1 0.1 0.0 4.0 100.4 0.6 0.4 5.1 1.6 GLP1R GLP-1R ENSG00000112164 "Glucagon like peptide 1 receptor" P43220 6 39048781-39091303 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;heart muscle: 2.7;pancreas: 7.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.2;Early spermatids: 1.0;Inhibitory neurons: 1.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.1;SCLC-21H: 2.7" "Region enriched" "Detected in many" 4 "basal ganglia: 20.7" "Low region specificity" "Detected in some" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.06e-3)" "unprognostic (5.38e-6)" "unprognostic (1.80e-2)" "unprognostic (4.16e-2)" "unprognostic (4.98e-2)" "unprognostic (3.55e-1)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (9.76e-2)" "unprognostic (3.29e-1)" "unprognostic (1.73e-1)" "unprognostic (8.60e-3)" "unprognostic (2.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.42e-2)" 0.1 0.0 0.4 0.0 0.9 0.0 0.6 0.3 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.7 0.6 3.7 0.1 0.0 0.3 0.1 1.1 0.5 0.0 7.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.9 0.2 1.6 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.5 0.6 3.7 1.1 0.5 1.2 1.1 1.6 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLRX5 "C14orf87, GRX5, PR01238" ENSG00000182512 "Glutaredoxin 5" Q86SX6 14 95533503-95544724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 518.5;Erythroid cells: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042465, HPA063716" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA042465: AB_10794048, HPA063716: AB_2685102" "unprognostic (2.57e-1)" "unprognostic (6.76e-2)" "unprognostic (1.60e-2)" "unprognostic (2.69e-2)" "unprognostic (3.72e-2)" "unprognostic (2.43e-3)" "unprognostic (1.29e-1)" "unprognostic (5.41e-2)" "unprognostic (8.28e-2)" "prognostic favorable (1.08e-5)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.83e-10)" "unprognostic (1.44e-1)" "unprognostic (3.81e-2)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 37.2 52.1 44.1 17.6 44.9 178.8 27.2 43.8 50.2 22.3 46.7 44.8 46.2 19.2 39.0 24.5 23.6 17.5 76.9 46.6 45.8 74.5 105.5 18.3 23.1 43.3 44.5 32.8 31.5 46.3 18.9 37.8 44.3 26.8 37.3 10.1 29.3 29.6 195.0 18.3 33.2 24.4 42.9 20.8 34.2 35.7 46.2 40.3 26.7 168.9 27.0 24.5 15.0 42.9 77.1 92.7 61.4 68.0 74.2 57.5 202.0 54.9 56.1 69.4 69.1 124.8 87.5 111.7 77.4 42.8 39.2 75.5 116.5 79.6 71.5 68.5 94.4 100.3 63.4 202.2 73.5 160.9 96.5 55.4 74.1 49.9 81.1 28.1 76.1 94.4 115.7 88.3 61.2 205.5 133.6 165.9 81.5 89.7 107.8 220.8 184.3 67.8 93.3 89.3 127.9 75.2 54.8 81.3 87.7 59.9 107.7 72.6 55.6 30.5 65.0 77.6 85.7 41.7 57.9 92.0 67.2 99.8 72.2 0.4 2.9 4.8 3.4 4.3 4.9 4.6 4.6 6.0 4.7 5.4 3.7 3.9 1.3 3.9 2.7 9.0 6.2 1.8 44.1 44.9 43.8 50.2 46.6 45.8 43.3 44.5 44.3 42.9 46.2 42.9 78.7 28.9 30.0 7.8 41.1 108.5 58.7 7.5 61.5 38.5 112.8 135.9 150.0 64.3 10.4 95.6 33.3 97.8 66.5 76.3 518.5 15.2 312.0 49.7 61.5 58.9 54.0 1134.9 15.0 15.6 164.9 66.2 46.4 48.3 14.7 110.3 47.2 147.2 58.7 50.5 16.4 72.1 4.1 41.7 58.7 90.2 54.3 50.7 87.2 7.5 21.3 128.1 52.5 12.5 15.2 15.2 39.5 73.7 75.2 108.2 51.8 281.4 9.1 43.0 59.2 61.1 92.7 115.4 79.0 102.2 124.9 53.8 48.8 169.0 88.0 76.6 GMPR ENSG00000137198 "Guanosine monophosphate reductase" P36959 6 16238587-16295549 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 358.6;tongue: 205.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Endometrial ciliated cells: 118.2;Erythroid cells: 367.1;Melanocytes: 92.5" "Cancer enhanced" "Detected in all" "melanoma: 95.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9" "Group enriched" "Detected in all" 6 "granulocytes: 14.9;monocytes: 5.0;NK-cells: 9.6" "Cell line enhanced" "Detected in many" "HEL: 193.1;HMC-1: 314.7;SK-MEL-30: 74.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000904, HPA021476" Uncertain NA NA 950000 "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA000904: AB_1078998, HPA021476: AB_1849858" "unprognostic (2.74e-1)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "unprognostic (4.97e-3)" "unprognostic (3.52e-2)" "unprognostic (1.05e-1)" "unprognostic (3.06e-1)" "prognostic favorable (8.07e-4)" "unprognostic (4.12e-1)" "prognostic favorable (2.06e-4)" "unprognostic (3.15e-1)" "unprognostic (2.86e-1)" "prognostic favorable (2.94e-5)" "unprognostic (3.01e-1)" "unprognostic (1.81e-1)" "unprognostic (7.31e-2)" "unprognostic (2.17e-1)" 10.0 23.3 28.5 2.8 31.9 29.7 6.5 32.4 21.6 6.6 35.7 15.5 2.7 13.3 16.5 5.3 56.9 3.7 101.7 19.6 38.2 25.5 5.9 9.1 2.5 36.8 45.6 38.0 18.3 14.2 24.9 7.8 35.0 63.1 3.4 2.2 21.5 9.0 358.6 12.4 6.0 9.9 39.7 12.5 36.5 52.3 41.3 6.5 4.4 205.0 1.6 5.2 3.7 33.2 0.0 0.0 0.3 0.0 2.7 2.1 0.1 3.9 15.7 27.2 55.2 1.6 0.4 0.0 8.8 6.0 19.1 0.1 6.7 0.8 4.5 0.0 5.0 193.1 0.1 0.0 11.8 0.8 314.7 3.7 2.8 8.5 0.0 22.2 49.5 0.7 43.9 0.3 4.8 3.8 0.2 4.1 2.0 0.2 7.5 0.0 41.9 0.0 36.1 5.4 9.4 1.2 1.9 3.2 74.4 12.1 3.0 1.4 12.5 0.4 0.2 1.3 7.5 2.3 0.0 0.0 0.9 20.3 21.8 14.9 3.3 0.4 0.7 5.0 1.2 0.2 0.1 0.5 1.5 1.5 0.0 0.2 3.3 9.6 1.7 1.5 0.0 16.0 28.5 31.9 32.4 21.6 19.6 38.2 36.8 45.6 35.0 39.7 41.3 33.2 4.6 0.0 0.0 8.8 1.3 5.1 30.2 0.7 0.6 0.7 5.3 3.8 52.8 35.8 2.7 20.2 0.0 25.3 0.6 1.4 86.1 12.4 16.0 118.2 8.7 6.8 7.8 367.1 3.8 4.9 2.8 10.2 9.2 78.9 55.3 38.9 17.9 5.0 8.9 0.0 11.5 3.2 4.1 6.4 2.1 16.3 34.5 47.4 92.5 2.8 9.2 9.8 2.1 3.0 1.7 3.0 1.2 80.9 1.4 69.9 2.2 15.5 6.4 0.8 0.0 12.6 7.4 6.5 17.2 1.3 1.8 6.8 3.5 19.4 3.8 8.3 GPD1 ENSG00000167588 "Glycerol-3-phosphate dehydrogenase 1" P21695 12 50103982-50111313 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 609.9;skeletal muscle: 577.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 99.1;Proximal enterocytes: 247.0;Proximal tubular cells: 298.4" "Cancer enhanced" "Detected in many" "liver cancer: 18.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 134.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044620, HPA058621" Enhanced NA NA 4700000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044620: AB_10796803, HPA058621: " "unprognostic (2.65e-2)" "unprognostic (5.60e-2)" "unprognostic (3.28e-2)" "unprognostic (3.37e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (1.45e-3)" "unprognostic (7.19e-2)" "unprognostic (9.42e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (3.24e-1)" "unprognostic (1.37e-1)" "unprognostic (9.58e-2)" "unprognostic (3.37e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" 609.9 4.7 9.1 1.6 16.8 0.2 229.2 22.7 12.8 0.3 5.5 6.4 76.4 0.2 5.3 4.9 0.5 16.6 9.2 10.1 14.2 149.3 147.6 18.4 1.0 32.6 18.3 0.3 7.2 13.0 1.3 0.0 26.5 1.3 3.3 1.0 33.0 1.3 577.1 10.2 76.9 1.3 32.7 0.4 3.3 0.8 18.4 1.5 2.7 215.7 0.4 4.1 1.0 49.4 0.1 0.2 0.1 0.1 134.0 0.0 0.3 0.1 0.0 0.0 0.0 27.0 0.1 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.1 0.6 25.2 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.7 0.7 0.3 0.0 0.2 0.1 0.4 0.1 3.7 0.0 0.2 0.2 30.2 0.2 0.0 0.6 0.2 0.0 1.5 1.0 0.0 1.8 0.0 0.0 0.0 0.3 0.2 0.1 0.6 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 16.8 22.7 12.8 10.1 14.2 32.6 18.3 26.5 32.7 18.4 49.4 3.4 3.2 3.2 0.0 2.4 0.0 0.2 0.3 0.6 3.2 3.4 3.7 5.8 11.5 1.8 5.5 8.4 0.0 0.0 3.0 43.0 0.9 0.1 0.5 0.1 0.2 1.2 5.3 0.2 0.7 0.0 0.8 4.1 0.2 0.0 0.1 1.1 99.1 2.3 3.3 0.2 9.7 0.0 1.0 0.4 0.0 0.0 5.2 1.8 0.0 1.0 2.8 0.0 0.0 4.0 0.6 8.0 0.0 0.0 0.1 247.0 298.4 0.4 1.7 0.0 7.0 1.1 0.0 0.0 0.8 0.4 0.0 1.2 0.0 10.6 0.2 GPD1L KIAA0089 ENSG00000152642 "Glycerol-3-phosphate dehydrogenase 1 like" Q8N335 3 32105689-32168709 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.4;tongue: 253.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 154.1;Distal enterocytes: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 136.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.23e-1)" "unprognostic (3.12e-2)" "prognostic favorable (7.05e-4)" "unprognostic (2.63e-1)" "unprognostic (9.67e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (1.35e-5)" "prognostic favorable (5.71e-5)" "unprognostic (2.49e-2)" "unprognostic (1.74e-1)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.33e-15)" "unprognostic (1.50e-1)" "unprognostic (1.99e-1)" "unprognostic (2.31e-3)" "unprognostic (5.51e-3)" 39.0 44.7 18.2 8.3 20.1 6.9 30.6 17.2 21.2 22.8 27.1 40.1 26.5 11.6 9.8 40.9 19.1 9.2 124.8 21.2 20.5 34.2 2.8 31.3 9.0 19.2 18.6 16.6 21.6 32.8 5.9 20.8 19.3 59.9 36.7 9.8 22.0 41.2 158.4 10.3 29.0 16.6 20.5 12.8 29.7 6.1 18.3 6.8 40.3 253.1 10.2 31.0 12.9 21.9 11.1 10.0 3.5 15.3 49.3 11.9 136.1 8.8 3.1 9.2 7.1 10.7 5.2 19.4 13.2 6.2 11.3 12.6 23.4 9.3 11.6 8.3 21.4 11.3 13.2 16.8 12.4 29.4 39.3 35.5 12.1 8.9 12.5 9.4 16.3 15.7 8.0 6.1 7.3 15.1 12.6 11.0 2.1 27.6 44.8 23.1 15.7 40.0 14.6 66.8 15.1 15.0 6.7 61.1 25.0 4.8 38.7 14.1 8.6 10.5 4.9 16.3 23.6 4.3 2.0 19.3 24.0 22.3 6.0 0.5 2.8 5.7 3.3 3.2 8.0 1.5 4.1 4.0 5.6 1.2 2.5 3.7 1.4 7.4 2.1 4.4 8.8 2.8 18.2 20.1 17.2 21.2 21.2 20.5 19.2 18.6 19.3 20.5 18.3 21.9 10.2 28.9 41.8 1.3 4.1 4.6 5.3 3.5 8.6 4.1 20.3 10.7 154.1 2.8 18.6 9.2 2.1 36.4 10.8 75.2 39.2 2.0 8.0 5.3 4.4 10.5 7.8 6.9 23.1 3.7 6.1 10.5 17.3 9.2 39.3 9.8 13.2 0.7 10.0 1.7 23.7 21.3 26.4 6.3 5.7 20.7 5.9 4.4 8.8 24.4 2.3 32.9 7.2 3.0 11.1 4.3 21.6 12.8 8.7 13.8 33.9 18.4 15.0 3.9 0.0 8.0 8.7 0.8 2.1 32.3 7.0 27.1 10.4 3.3 26.9 8.5 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPR22 ENSG00000172209 "G protein-coupled receptor 22" Q99680 7 107470018-107475684 "G-protein coupled receptors, Predicted membrane proteins" "Cilium biogenesis/degradation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;cervix: 2.1;heart muscle: 8.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Cardiomyocytes: 57.9;Excitatory neurons: 49.9;Inhibitory neurons: 51.2;Oligodendrocyte precursor cells: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 27 "SH-SY5Y: 2.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 60.4" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.23e-2)" "unprognostic (1.25e-2)" "unprognostic (1.19e-1)" "unprognostic (5.52e-2)" "unprognostic (7.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.27e-3)" "unprognostic (1.62e-1)" "unprognostic (8.76e-3)" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (5.85e-4)" "unprognostic (1.55e-1)" "unprognostic (7.53e-3)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" 0.0 0.9 1.0 0.0 1.9 0.0 0.0 2.5 2.7 2.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 8.2 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.9 2.5 2.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 3.9 0.1 0.3 0.0 0.0 0.0 15.3 0.0 0.0 57.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.5 1.8 0.4 0.0 0.0 49.9 0.0 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.0 0.1 5.0 51.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 6.5 0.0 0.7 0.0 12.5 7.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.6 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 GPR61 BALGR ENSG00000156097 "G protein-coupled receptor 61" Q9BZJ8 1 109539872-109548406 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.2;pituitary gland: 3.5;retina: 3.2" "Group enriched" "Detected in some" 5 "Bipolar cells: 18.9;Cone photoreceptor cells: 6.2;Excitatory neurons: 8.2;Inhibitory neurons: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007326, HPA026088" Supported NA NA "Cluster 58: Brain - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" "HPA007326: AB_1849308, HPA026088: AB_10602323" "unprognostic (1.70e-1)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (2.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.70e-2)" "unprognostic (7.51e-2)" "unprognostic (3.63e-3)" "unprognostic (2.94e-2)" "unprognostic (4.50e-2)" "unprognostic (1.46e-4)" "unprognostic (3.27e-1)" "unprognostic (4.08e-4)" "unprognostic (1.33e-1)" "unprognostic (1.07e-1)" "unprognostic (6.72e-2)" "unprognostic (3.85e-2)" 0.0 0.7 1.2 0.0 1.7 0.0 0.0 0.2 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.3 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.7 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.7 0.2 3.2 1.3 0.3 0.1 0.4 0.0 0.0 1.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 18.9 0.2 0.0 0.6 0.0 0.0 0.0 6.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 1.7 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.0 0.8 0.0 0.0 1.5 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 GPSM1 "AGS3, DKFZP727I051" ENSG00000160360 "G protein signaling modulator 1" Q86YR5 9 136327476-136359605 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.1;Bipolar cells: 37.2;Cone photoreceptor cells: 22.9;Muller glia cells: 36.0;Rod photoreceptor cells: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042199, HPA060736" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" Nucleoplasm "HPA042199: AB_10959329, HPA060736: " "unprognostic (1.73e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.07e-3)" "unprognostic (3.44e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-2)" "unprognostic (2.03e-2)" "unprognostic (1.48e-1)" "unprognostic (5.96e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (4.66e-2)" "unprognostic (1.84e-1)" "unprognostic (6.42e-2)" "unprognostic (7.48e-2)" 13.0 21.7 32.6 4.2 30.6 4.5 12.4 50.9 44.4 38.7 12.7 18.5 3.3 23.3 7.2 6.0 20.3 4.7 74.9 30.5 26.7 19.6 4.7 35.4 2.1 34.9 29.8 38.1 42.3 3.8 19.7 6.6 28.7 30.6 1.2 18.7 8.6 5.9 2.7 17.0 9.3 4.0 25.1 19.9 17.2 29.4 28.6 2.0 12.4 0.7 1.1 15.1 24.4 28.6 3.9 6.2 14.5 25.4 8.1 14.1 12.1 43.0 17.6 11.8 6.4 12.5 4.1 0.0 17.8 26.0 9.9 2.9 2.3 8.8 2.6 35.1 25.5 5.0 23.4 2.3 34.7 0.3 6.1 23.0 5.8 10.8 6.2 14.5 12.0 5.9 13.5 0.2 7.9 14.2 2.4 4.9 15.5 1.4 22.5 82.3 26.2 12.7 3.2 2.8 35.6 44.4 8.0 1.0 13.7 5.6 17.7 8.6 20.0 21.7 17.5 25.7 8.9 7.6 0.3 0.1 13.0 0.0 21.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 32.6 30.6 50.9 44.4 30.5 26.7 34.9 29.8 28.7 25.1 28.6 28.6 4.7 3.2 3.3 26.1 0.6 4.2 2.3 0.8 0.0 37.2 2.5 5.8 12.4 0.0 0.8 0.0 22.9 0.6 1.6 0.0 11.7 3.3 0.6 2.7 18.1 3.9 1.8 2.5 9.0 1.9 0.8 9.1 0.5 5.5 5.7 14.2 3.6 0.0 1.1 10.1 11.6 0.0 0.0 0.3 2.8 1.3 10.5 1.5 8.8 6.5 0.5 36.0 0.0 9.5 10.4 7.3 0.0 9.4 0.3 10.6 0.0 0.1 0.6 43.0 0.0 5.8 6.0 0.4 3.7 0.1 3.3 0.3 1.1 3.3 0.0 4.0 GRIN2A "GluN2A, NMDAR2A" ENSG00000183454 "Glutamate ionotropic receptor NMDA type subunit 2A" Q12879 16 9753404-10182928 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 31.7" "Group enriched" "Detected in some" 13 "Excitatory neurons: 839.8;Inhibitory neurons: 904.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 31.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.4;RPMI-8226: 1.8;U-138 MG: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022725 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022725: " "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-2)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (2.08e-1)" "unprognostic (5.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (4.79e-3)" "unprognostic (2.05e-1)" "unprognostic (3.92e-3)" "unprognostic (3.33e-2)" 0.3 0.3 4.7 0.0 8.4 0.0 0.1 0.0 31.7 0.3 0.0 0.2 0.3 0.3 2.5 1.1 2.1 0.1 3.0 20.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 2.2 0.2 0.3 0.0 0.5 0.2 0.4 0.0 0.0 0.4 2.1 0.1 0.6 0.2 0.2 0.2 0.1 0.4 10.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.3 1.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.4 0.0 31.7 20.0 0.0 0.0 0.0 0.0 0.0 0.1 10.3 0.2 0.0 0.0 16.0 0.0 1.9 2.2 0.5 3.4 10.3 0.3 0.0 18.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2.1 17.2 0.3 0.1 0.5 0.0 0.0 839.8 0.2 0.0 2.7 0.0 0.7 0.0 3.3 0.0 0.3 0.1 1.7 904.7 0.0 0.0 0.3 0.4 15.1 0.9 0.1 0.0 15.9 0.0 15.6 0.0 27.6 65.8 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.9 0.0 0.0 5.4 8.2 10.0 0.2 0.4 0.0 0.0 0.0 0.1 0.3 GRIP2 KIAA1719 ENSG00000144596 "Glutamate receptor interacting protein 2" Q9C0E4 3 14489107-14556075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13.3;skeletal muscle: 35.8;tongue: 12.5" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 89.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.9;NTERA-2: 2.1;PC-3: 6.1;SCLC-21H: 3.4;U-2 OS: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035673 Approved Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA035673: AB_10669776" "unprognostic (1.48e-1)" "unprognostic (6.26e-3)" "unprognostic (2.43e-2)" "unprognostic (3.13e-2)" "unprognostic (5.51e-2)" "unprognostic (1.14e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-2)" "unprognostic (9.14e-2)" "unprognostic (2.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (5.82e-1)" "unprognostic (4.01e-1)" 1.1 1.1 3.0 0.7 2.7 0.0 1.0 0.0 6.2 1.1 0.0 0.8 0.4 1.1 0.4 2.2 0.8 1.2 13.3 0.2 3.5 2.3 0.3 0.4 0.4 2.9 5.8 3.4 0.5 0.3 1.0 3.9 2.1 0.9 1.0 0.3 0.9 0.4 35.8 2.0 1.0 1.0 1.7 1.6 4.5 0.7 9.6 0.3 0.8 12.5 0.7 1.0 1.2 1.8 0.1 0.9 0.0 0.0 0.3 0.2 0.0 0.3 3.1 0.3 1.9 1.2 0.0 0.0 0.7 0.2 0.5 0.2 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 1.5 6.1 0.0 0.0 0.0 0.0 0.0 3.4 0.6 0.3 0.0 1.0 1.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 6.2 0.2 3.5 2.9 5.8 2.1 1.7 9.6 1.8 2.3 0.0 0.5 2.3 0.1 0.0 0.1 0.0 1.2 14.9 0.1 1.3 8.5 0.0 0.6 0.0 14.6 0.0 0.7 0.1 0.0 0.0 3.0 2.1 1.4 0.8 4.2 0.0 3.0 0.2 0.0 2.0 2.0 4.9 0.0 0.0 1.1 0.0 0.1 0.0 89.0 0.1 0.0 0.0 0.0 5.2 4.1 0.7 0.0 2.8 0.0 0.5 0.0 0.5 0.9 0.0 0.0 2.2 0.3 0.1 0.0 0.2 0.0 21.9 19.7 4.3 14.7 0.1 0.8 0.2 0.0 0.1 0.3 1.1 0.0 0.0 GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667219-113737736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "retina: 42.6" "Group enriched" "Detected in some" 16 "Cone photoreceptor cells: 56.3;Rod photoreceptor cells: 84.9" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA035200: AB_2674515, HPA059376: AB_2683996" "unprognostic (7.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-5)" "unprognostic (1.76e-3)" "unprognostic (1.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.21e-2)" "unprognostic (1.84e-3)" "unprognostic (2.00e-2)" "unprognostic (4.02e-2)" "unprognostic (6.91e-2)" "unprognostic (6.18e-2)" "unprognostic (6.11e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GRM8 "GLUR8, GPRC1H, mGlu8, MGLUR8" ENSG00000179603 "Glutamate metabotropic receptor 8" O00222 7 126438598-127253093 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 44.3" "Cell type enhanced" "Detected in some" "Early spermatids: 59.5;Excitatory neurons: 104.9;Inhibitory neurons: 134.0;Late spermatids: 69.1;Oligodendrocyte precursor cells: 32.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.9;HEK 293: 1.4;NTERA-2: 3.5;RH-30: 2.4;SCLC-21H: 3.3;SH-SY5Y: 1.7;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051481 Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA051481: AB_2681499" "unprognostic (4.57e-3)" "unprognostic (5.10e-4)" "unprognostic (1.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.83e-1)" "unprognostic (5.54e-2)" "unprognostic (2.06e-4)" "unprognostic (1.79e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (3.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (1.32e-2)" "unprognostic (1.12e-2)" 0.0 0.6 3.0 0.3 3.3 0.0 0.0 0.7 3.7 0.1 44.3 1.7 0.1 0.0 0.0 0.0 0.1 0.5 2.4 4.5 4.7 0.6 3.6 0.2 0.0 8.1 8.4 0.8 0.5 0.0 0.3 0.0 9.0 0.1 2.0 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.7 2.7 0.0 0.9 0.0 0.1 0.5 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.0 2.4 0.0 0.1 0.0 3.3 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.3 0.7 3.7 4.5 4.7 8.1 8.4 9.0 0.0 2.7 1.8 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 1.1 1.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 59.5 0.0 0.0 0.6 1.2 0.0 104.9 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 1.2 0.0 0.0 134.0 0.7 0.0 0.0 0.0 69.1 0.6 0.0 0.0 13.1 0.0 0.3 0.0 32.6 9.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 1.2 1.6 0.0 0.0 0.0 0.0 0.1 0.9 0.0 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006311, HPA022904" Supported Supported Peroxisomes NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 39: Non-specific - Basic cellular processes" Peroxisomes "HPA006311: AB_1849786, HPA022904: AB_1849787" "prognostic favorable (4.41e-6)" "unprognostic (2.40e-1)" "unprognostic (6.53e-2)" "unprognostic (4.49e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-2)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.99e-2)" "unprognostic (7.27e-2)" "prognostic favorable (2.10e-6)" "unprognostic (2.66e-2)" "unprognostic (2.94e-1)" "unprognostic (9.13e-2)" "unprognostic (2.15e-2)" 150.9 180.9 77.5 135.9 82.5 187.0 159.1 82.7 89.2 154.5 141.0 217.9 317.2 95.2 110.7 154.0 144.7 140.6 271.7 75.7 82.7 257.2 449.3 125.1 185.0 85.2 84.0 71.1 138.0 308.2 79.7 104.2 85.3 111.4 230.8 26.9 213.0 96.4 238.6 132.6 277.1 106.6 79.8 236.5 163.4 85.1 83.3 96.2 160.1 324.1 183.7 129.5 112.4 88.6 150.7 106.1 14.7 130.1 224.2 319.7 68.8 87.0 148.4 76.3 150.8 64.5 375.2 85.4 120.8 126.7 114.5 222.4 57.5 136.2 66.0 165.0 62.3 69.6 80.9 102.9 154.1 84.7 108.4 290.4 164.3 88.0 62.0 113.1 205.3 109.5 99.3 100.9 207.2 116.2 87.3 152.9 34.7 291.3 158.6 73.9 2.4 169.6 266.1 81.6 59.7 81.4 159.4 256.3 137.4 88.3 123.6 117.0 122.2 41.0 37.7 108.5 75.2 171.0 86.5 20.0 148.5 336.0 86.6 351.1 537.1 210.7 298.5 597.9 289.7 254.5 554.6 386.4 445.2 183.2 281.3 274.6 165.0 188.3 641.7 187.0 800.5 917.1 77.5 82.5 82.7 89.2 75.7 82.7 85.2 84.0 85.3 79.8 83.3 88.6 181.9 70.5 95.6 17.0 134.1 114.2 174.9 244.0 118.4 11.6 181.9 198.2 172.9 211.6 219.5 121.4 12.5 295.3 151.4 301.6 291.6 160.5 561.3 102.7 95.8 117.0 153.6 63.3 25.8 120.3 132.0 96.4 185.5 92.9 145.1 47.4 155.3 322.1 304.2 8.4 28.8 252.8 154.6 288.3 174.1 1160.2 72.7 195.8 151.2 16.9 228.5 85.9 194.7 16.6 14.3 104.5 505.2 50.8 130.0 82.9 670.0 620.2 154.0 15.4 85.5 65.9 121.7 6.9 10.3 166.3 116.4 183.7 250.7 150.7 366.5 218.9 GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 377.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 802.2;Early spermatids: 2092.4;Late spermatids: 3843.4;Spermatocytes: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 3.4;gdT-cell: 3.1;memory CD4 T-cell: 3.9;memory CD8 T-cell: 2.2;naive CD4 T-cell: 7.8;naive CD8 T-cell: 4.3;T-reg: 1.9" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;T-cells: 7.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 228.4;T-47d: 479.6;WM-115: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Approved Cytosol NA NA 790000 "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017130: , CAB040583: , HPA035190: AB_10795023, HPA055972: AB_2682992" "unprognostic (2.13e-2)" "unprognostic (2.76e-2)" "unprognostic (1.95e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.28e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.89e-4)" "unprognostic (3.45e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-1)" "unprognostic (6.16e-3)" "unprognostic (1.38e-2)" "unprognostic (1.21e-2)" "unprognostic (1.90e-2)" "unprognostic (3.48e-2)" 38.7 39.0 56.9 11.0 61.1 3.3 83.5 50.3 69.1 52.7 109.7 45.0 46.8 32.1 243.2 53.6 35.1 47.0 74.8 56.9 63.6 188.1 20.0 23.6 6.2 54.4 54.8 120.4 101.0 41.1 33.7 21.6 55.5 47.5 19.9 21.1 22.6 165.9 65.8 57.2 27.8 58.3 57.5 14.1 76.2 377.9 61.6 13.2 57.9 51.2 7.9 57.1 53.2 58.3 0.2 6.9 49.3 0.1 64.5 39.9 8.5 54.3 9.4 58.2 56.2 21.8 1.9 0.1 30.8 27.8 40.1 2.6 10.0 22.3 80.5 0.3 14.9 50.8 152.1 33.9 69.5 0.0 115.2 40.3 27.0 87.8 0.1 63.5 73.1 61.9 4.7 0.6 26.6 30.0 14.5 1.2 5.3 0.2 93.1 0.4 31.9 2.3 16.3 117.1 86.1 46.0 112.5 228.4 10.5 14.1 479.6 75.3 57.9 0.8 20.9 59.6 36.3 7.7 13.1 0.2 0.6 0.1 186.9 0.3 0.1 3.4 3.1 0.1 0.8 0.3 3.9 2.2 0.1 0.2 7.8 4.3 0.9 0.7 0.1 0.5 1.9 1.5 56.9 61.1 50.3 69.1 56.9 63.6 54.4 54.8 55.5 57.5 61.6 58.3 22.2 6.4 11.5 18.3 7.0 143.5 97.2 104.4 50.1 17.5 196.1 176.8 88.0 50.1 35.9 222.5 6.2 16.3 8.7 17.3 802.2 88.0 2092.4 51.4 40.6 32.9 50.4 33.0 7.5 149.5 9.0 131.6 43.8 93.6 9.5 22.7 58.2 14.2 10.6 15.2 8.0 24.9 28.5 13.9 54.1 3843.4 385.5 15.1 60.5 2.8 3.5 247.5 2.1 14.6 1.7 126.4 32.5 276.1 3.4 53.7 116.9 38.9 5.4 19.2 190.7 23.8 94.4 1177.6 54.4 71.9 107.4 10.3 24.4 121.4 44.1 80.8 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109674836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 149.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 382.8;Proximal tubular cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 351.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 351.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 22.3 31.1 19.7 15.3 23.7 5.9 22.5 19.1 23.8 24.5 40.0 45.4 149.5 22.6 24.3 31.3 22.2 17.8 33.5 19.2 19.9 45.9 41.2 14.6 11.8 20.7 20.9 42.9 21.2 57.8 18.6 7.6 20.2 25.8 38.5 12.5 21.2 41.0 92.4 20.6 99.4 25.7 21.1 30.2 28.8 15.1 20.1 9.9 27.7 45.5 15.6 36.8 28.8 20.2 13.5 6.0 10.5 78.9 23.0 35.1 13.4 4.3 34.1 9.8 12.8 43.3 1.5 12.5 16.1 19.1 19.3 13.6 27.1 14.4 6.2 18.9 0.0 27.4 23.5 38.8 37.1 9.5 31.8 22.3 14.0 12.6 0.0 27.5 8.1 31.7 12.8 18.4 6.9 12.7 8.1 41.9 8.2 56.3 31.9 16.9 5.8 18.5 38.8 9.6 7.4 17.6 0.2 68.2 54.9 7.8 18.6 20.1 3.6 11.4 44.0 12.5 6.3 27.0 51.4 1.1 37.1 13.9 32.5 11.9 14.5 351.7 12.2 14.5 7.4 17.0 9.3 14.1 37.8 14.9 8.9 10.7 1.8 12.8 3.6 12.6 14.1 12.6 19.7 23.7 19.1 23.8 19.2 19.9 20.7 20.9 20.2 21.1 20.1 20.2 6.9 9.6 2.7 11.4 9.9 18.1 27.3 17.9 18.8 6.2 14.7 19.0 30.2 21.5 9.5 31.3 0.0 21.0 13.9 53.0 101.8 45.9 3.0 4.5 10.8 8.6 7.2 4.2 3.3 57.7 18.6 22.9 13.3 5.4 21.0 13.3 14.3 35.7 35.6 5.0 3.3 45.9 6.1 17.2 26.0 6.4 30.1 14.9 40.9 2.8 14.8 23.9 17.5 5.0 3.4 35.4 38.6 24.8 13.3 6.7 382.8 109.8 7.5 5.4 32.9 15.3 23.2 7.0 7.3 23.0 15.3 8.8 11.2 12.6 96.7 26.9 GSTZ1 "GSTZ1-1, MAAI, MAI" ENSG00000100577 "Glutathione S-transferase zeta 1" O43708 14 77320996-77331597 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Isomerase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 263.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 373.2;Late spermatids: 398.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 182.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004701 Approved Approved Nucleoplasm,Cytosol NA NA 340000 "Cluster 18: Basophils - Vesicular transport" "Cluster 62: Liver - Hemostasis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol Nucleoplasm "HPA004701: AB_1078990" "prognostic favorable (4.93e-4)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (2.16e-3)" "unprognostic (4.55e-1)" "unprognostic (3.03e-2)" "unprognostic (8.03e-3)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "prognostic favorable (3.73e-4)" "unprognostic (7.90e-2)" "unprognostic (1.73e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (4.12e-1)" "unprognostic (4.92e-2)" 13.9 34.7 11.1 9.7 12.5 9.3 23.2 13.2 16.3 12.7 10.5 21.9 22.5 10.8 22.1 26.9 14.9 11.9 14.3 10.5 12.3 24.5 263.1 7.8 13.5 12.6 11.7 6.5 20.1 26.4 13.3 11.2 12.8 21.1 21.7 5.1 24.1 9.6 47.4 22.1 15.6 7.9 12.3 12.1 18.9 57.8 11.9 14.0 19.5 37.3 17.4 11.9 13.8 14.0 18.8 39.0 27.6 19.9 17.1 23.9 45.8 11.4 11.9 21.6 30.9 13.0 45.2 43.5 14.9 13.6 13.4 24.1 18.9 22.5 20.7 23.2 21.0 20.8 13.3 26.9 26.3 7.8 15.8 22.1 24.0 12.4 20.8 12.0 18.6 24.7 17.5 37.0 14.5 182.1 12.2 16.4 8.2 64.1 30.3 20.2 29.5 34.2 32.5 24.0 30.2 26.2 26.0 49.1 35.6 15.5 81.2 11.1 13.8 17.0 52.5 18.9 8.6 28.2 32.7 35.2 41.9 11.3 20.8 13.4 15.5 9.9 2.6 22.2 2.4 8.2 4.6 3.7 20.7 10.4 3.9 3.1 1.6 5.1 20.1 15.0 7.9 7.4 11.1 12.5 13.2 16.3 10.5 12.3 12.6 11.7 12.8 12.3 11.9 14.0 6.1 6.4 9.6 6.5 13.5 13.4 19.8 26.2 15.9 7.3 36.1 34.2 13.0 47.1 19.0 9.2 4.2 91.4 7.5 34.9 46.9 45.0 125.8 19.4 15.6 11.1 28.8 30.3 2.9 68.0 62.5 15.0 33.1 27.0 3.8 25.7 15.4 373.2 44.6 16.8 3.3 45.7 20.3 38.1 10.9 398.1 11.8 19.0 17.8 3.7 30.4 26.4 4.1 2.0 9.2 41.8 37.4 6.0 13.2 19.8 72.9 77.8 15.0 11.9 0.0 12.3 13.2 51.3 29.4 38.0 14.1 76.2 6.7 55.8 50.3 30.3 GUCA1C GCAP3 ENSG00000138472 "Guanylate cyclase activator 1C" O95843 3 108907792-108953879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 296.7" "Cell type enriched" "Detected in some" 4 "Cone photoreceptor cells: 125.1" "Cancer enriched" "Detected in single" 7 "pancreatic cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 85 "RPTEC TERT1: 14.0" HPA041597 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Focal adhesion sites" "HPA041597: AB_10795501" "unprognostic (7.56e-2)" "unprognostic (6.56e-2)" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 1.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.4 41.5 0.0 0.4 0.0 0.1 0.0 0.0 296.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 1.3 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.3 1.0 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 14.5 0.0 0.0 0.0 125.1 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.3 0.0 0.0 0.7 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 1.0 0.0 9.7 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 29.6 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 17.5 0.0 0.0 GYS1 "GSY, GYS" ENSG00000104812 "Glycogen synthase 1" P13807 19 48968130-48993310 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 118.5;skeletal muscle: 319.4;tongue: 201.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007793, HPA041598" Enhanced Approved Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "CAB007793: AB_562291, HPA041598: AB_2677571" "unprognostic (3.37e-1)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (6.83e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (3.30e-2)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.46e-4)" "unprognostic (4.04e-2)" "unprognostic (6.76e-2)" "unprognostic (5.87e-3)" "unprognostic (3.81e-2)" 32.4 26.3 17.9 16.2 18.8 46.0 23.7 26.4 23.3 17.1 22.2 21.7 15.3 18.8 8.9 38.2 18.7 10.1 118.5 19.7 17.6 21.8 14.9 16.0 15.5 22.2 20.9 19.7 13.6 15.7 15.5 11.3 19.6 27.4 14.7 19.2 22.2 15.5 319.4 20.7 19.9 16.7 16.4 18.5 23.2 6.1 20.2 14.7 15.9 201.6 14.4 24.3 23.2 18.3 67.3 26.3 19.0 26.3 43.2 16.9 37.6 45.5 31.7 46.8 54.3 25.8 21.3 28.0 27.0 44.7 12.4 46.6 32.0 57.7 40.6 17.4 46.5 23.1 33.3 23.1 24.3 25.4 15.9 41.8 27.2 30.2 25.4 40.5 39.8 28.8 16.4 36.1 59.4 25.4 31.8 21.9 10.2 29.0 29.8 26.6 33.2 27.5 46.7 70.6 11.8 16.4 40.5 52.1 10.4 25.2 27.7 26.1 31.0 57.1 22.0 26.1 50.5 29.8 33.1 13.5 58.3 22.2 13.1 7.7 9.4 6.6 7.0 5.3 8.6 5.2 6.0 6.5 13.4 3.9 4.7 4.4 3.7 10.6 8.0 7.2 8.6 7.1 17.9 18.8 26.4 23.3 19.7 17.6 22.2 20.9 19.6 16.4 20.2 18.3 3.5 0.0 14.2 21.9 5.9 5.1 3.7 11.7 11.4 4.2 7.3 5.5 67.9 2.8 5.8 0.0 16.7 7.6 6.8 13.2 0.0 8.1 0.3 6.9 8.9 7.1 7.2 4.8 14.7 6.9 31.7 5.0 12.8 11.9 4.5 6.7 9.7 5.2 8.3 0.0 16.6 9.2 4.1 7.0 5.7 0.7 5.3 7.2 7.2 4.7 9.8 3.3 10.3 8.5 6.9 11.8 8.2 5.7 9.7 5.4 9.2 6.0 6.2 11.7 0.0 5.0 7.3 1.3 2.9 15.3 4.1 4.0 5.2 3.8 11.7 3.3 H2AW "HIST3H2A, MGC3165" ENSG00000181218 "H2A.W histone" Q7L7L0 1 228456979-228457873 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 35.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.2;Cytotrophoblasts: 14.1;dendritic cells: 13.8;Extravillous trophoblasts: 10.8;Hofbauer cells: 28.4;Syncytiotrophoblasts: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 29.7;U-266/70: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (3.65e-3)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "unprognostic (2.71e-1)" "prognostic favorable (3.73e-4)" "unprognostic (1.84e-3)" "unprognostic (2.49e-2)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-2)" "unprognostic (3.20e-2)" "unprognostic (1.96e-1)" "unprognostic (6.67e-3)" "unprognostic (1.24e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" 6.0 35.9 6.3 0.8 6.1 5.9 6.8 13.4 6.9 27.9 9.9 5.9 3.2 5.4 1.6 19.2 7.2 1.2 17.8 5.8 6.7 4.4 1.1 4.4 1.2 5.0 4.9 14.1 3.9 3.7 12.9 1.0 5.3 11.1 0.9 4.9 10.3 0.4 1.0 18.0 5.5 0.3 5.0 13.0 6.3 5.8 6.9 1.8 2.1 0.7 0.9 5.4 24.2 5.5 5.9 3.1 4.0 5.6 3.3 3.3 4.8 2.9 2.8 8.2 5.7 3.1 4.8 2.7 3.4 0.6 0.0 14.3 2.9 1.4 1.9 4.2 29.7 4.2 4.0 0.0 7.6 3.0 8.1 7.3 8.4 1.5 3.5 3.3 3.5 5.4 15.0 0.0 0.0 8.4 3.9 0.0 6.2 3.5 7.5 0.0 0.0 22.9 1.4 3.5 24.7 17.4 10.2 8.9 20.7 0.6 15.7 2.2 1.3 0.0 0.1 11.0 2.6 29.4 22.4 0.0 2.9 3.0 2.1 4.4 1.4 0.0 5.8 2.8 4.3 2.7 5.5 4.3 3.0 2.1 4.2 4.1 0.6 6.5 7.0 0.5 10.4 3.4 6.3 6.1 13.4 6.9 5.8 6.7 5.0 4.9 5.3 5.0 6.9 5.5 0.5 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 14.1 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 10.8 2.6 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 53.8 2.4 0.0 0.0 0.0 H3C6 "H3.1, H3/d, H3FD, HIST1H3E" ENSG00000274750 "H3 clustered histone 6" P68431 6 26224199-26227473 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Hofbauer cells: 1.0;Syncytiotrophoblasts: 1.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 10.5;hTERT-RPE1: 7.5;SCLC-21H: 11.9;T-47d: 7.3" "Low region specificity" "Detected in all" HPA042570 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA042570: AB_2678056" "unprognostic (2.42e-2)" "unprognostic (1.78e-1)" "unprognostic (1.78e-3)" "unprognostic (9.07e-2)" "unprognostic (1.34e-1)" "unprognostic (3.65e-1)" "unprognostic (1.23e-1)" "unprognostic (3.90e-1)" "unprognostic (1.83e-1)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (7.66e-2)" 0.6 3.5 1.0 1.0 1.5 0.4 1.8 3.9 3.2 1.2 2.7 2.9 4.7 0.8 4.9 2.8 1.5 1.0 6.0 1.1 1.5 1.6 2.9 0.5 1.3 2.0 1.7 1.0 0.7 1.5 0.6 0.9 2.4 3.4 1.9 0.2 1.9 0.7 5.1 1.2 4.7 0.4 1.9 2.2 2.6 1.4 1.4 1.2 2.6 3.7 0.9 1.2 1.2 3.4 1.9 2.0 2.8 1.3 3.3 1.6 0.2 1.3 1.5 0.7 0.5 0.6 1.1 0.0 10.5 0.5 1.0 2.3 0.0 0.3 0.6 2.9 2.5 0.4 1.0 0.6 1.0 0.1 1.7 2.3 2.4 0.3 0.7 7.5 1.1 0.2 0.3 2.2 1.9 1.8 0.4 0.1 0.2 1.4 1.9 1.4 0.6 0.3 5.7 1.1 11.9 1.4 1.9 3.0 3.4 0.4 7.3 1.2 0.6 1.3 0.4 0.4 0.3 0.8 0.3 0.2 0.6 0.1 0.7 0.2 0.7 0.0 0.5 0.6 0.7 0.5 0.7 0.7 0.5 0.9 0.6 0.7 2.7 0.2 0.6 1.7 1.3 0.5 1.0 1.5 3.9 3.2 1.1 1.5 2.0 1.7 2.4 1.9 1.4 3.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HAGH "GLO2, GLXII, HAGH1" ENSG00000063854 "Hydroxyacylglutathione hydrolase" Q16775 16 1795620-1827157 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 378.7;Proximal tubular cells: 501.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043041, HPA061143" Approved NA NA 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA043041: AB_2678284, HPA061143: AB_2684439" "unprognostic (3.11e-1)" "prognostic favorable (5.82e-5)" "unprognostic (2.54e-1)" "unprognostic (1.93e-2)" "unprognostic (5.84e-2)" "unprognostic (1.54e-1)" "prognostic favorable (5.33e-6)" "unprognostic (5.78e-3)" "unprognostic (3.34e-2)" "unprognostic (7.69e-2)" "unprognostic (3.34e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.81e-6)" "unprognostic (1.20e-1)" "unprognostic (6.24e-2)" "unprognostic (7.18e-3)" "prognostic favorable (5.19e-4)" 41.2 109.0 81.5 20.2 84.2 82.1 35.1 82.7 103.9 22.8 78.9 53.7 45.3 24.6 31.1 29.0 28.5 21.9 138.6 89.9 83.8 100.1 236.2 39.2 24.6 82.8 80.2 22.0 63.5 54.0 72.7 23.1 83.7 33.5 23.3 32.2 32.5 37.7 198.8 31.2 44.8 24.7 80.1 35.2 52.9 91.7 84.0 35.8 35.1 156.2 18.4 34.8 24.6 87.6 31.1 46.1 40.9 46.5 35.1 13.8 37.0 38.1 35.2 57.7 46.1 23.7 26.5 6.4 76.5 32.9 39.6 33.2 39.1 38.2 17.2 64.5 63.4 12.0 47.9 69.3 50.2 15.7 62.6 16.9 80.6 28.8 19.6 50.6 50.1 79.8 16.1 56.3 18.3 51.2 41.1 34.0 15.7 32.0 42.3 34.2 25.8 73.6 74.5 13.8 54.7 47.4 41.8 52.9 84.9 30.8 38.7 52.0 38.7 17.5 21.5 36.9 44.6 63.3 64.7 19.8 29.8 14.5 28.5 37.3 33.3 64.9 26.0 59.1 19.0 31.3 34.0 27.3 30.7 30.4 32.0 27.4 29.7 25.5 88.2 64.8 42.8 30.3 81.5 84.2 82.7 103.9 89.9 83.8 82.8 80.2 83.7 80.1 84.0 87.6 46.2 9.6 39.0 11.8 33.7 23.8 45.1 59.7 12.0 117.1 39.5 31.1 84.2 65.8 39.7 46.0 64.6 52.4 43.2 60.9 158.5 45.6 193.1 75.0 12.1 35.3 39.6 378.7 24.6 38.3 38.5 25.6 23.9 35.5 30.4 36.0 41.0 186.9 76.2 138.0 22.2 41.2 93.6 49.0 41.6 60.1 46.9 47.6 55.2 12.2 50.1 95.2 64.9 7.1 19.7 49.7 68.8 54.9 50.4 48.3 168.9 501.7 70.2 117.0 72.3 33.3 61.1 245.2 68.3 29.1 45.6 68.7 44.1 45.3 39.9 49.9 HAND1 "bHLHa27, eHand, Hxt, Thing1" ENSG00000113196 "Heart and neural crest derivatives expressed 1" O96004 5 154474972-154478227 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 24.3;intestine: 66.1" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 15.2" "Cancer enriched" "Detected in some" 5 "testis cancer: 2.8" "Region enriched" "Detected in single" 4 "thalamus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "SH-SY5Y: 119.5;SuSa: 212.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040925, HPA075313" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA040925: AB_10796563, HPA075313: " "unprognostic (2.37e-2)" "unprognostic (8.29e-2)" "unprognostic (2.46e-3)" "unprognostic (7.23e-2)" "unprognostic (5.21e-2)" "unprognostic (6.38e-3)" 0.2 4.7 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 3.7 0.0 0.0 0.0 0.0 0.5 24.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 14.3 12.3 0.0 0.0 0.0 0.3 1.5 0.1 0.0 0.0 0.0 7.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 119.5 0.0 0.0 0.0 212.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 15.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.6 1.7 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.1 1.1 0.0 0.0 0.2 0.0 HAND2 "bHLHa26, dHand, Hed, Thing2" ENSG00000164107 "Heart and neural crest derivatives expressed 2" P61296 4 173524969-173530229 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 60.5" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 100.3;Endometrial stromal cells: 317.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.5;stomach cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "SH-SY5Y: 410.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019591, CAB025576" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Vesicles "CAB025576: , HPA019591: AB_2670199" "unprognostic (4.11e-2)" "unprognostic (7.50e-3)" "unprognostic (2.43e-2)" "unprognostic (1.25e-2)" "unprognostic (1.95e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "unprognostic (2.24e-1)" "unprognostic (1.28e-2)" "unprognostic (2.56e-1)" "unprognostic (2.44e-1)" "unprognostic (1.35e-1)" "unprognostic (3.27e-2)" "unprognostic (4.95e-2)" "unprognostic (1.56e-1)" "unprognostic (6.39e-3)" 4.9 28.0 0.0 5.4 0.0 0.0 2.1 0.5 0.0 22.2 0.0 60.5 2.5 33.4 0.3 1.0 16.0 16.2 36.8 0.0 0.0 0.1 5.5 0.0 0.2 0.0 0.0 15.3 4.1 0.0 0.1 20.9 0.2 1.3 4.4 0.0 0.8 1.0 0.2 1.5 11.0 27.3 0.0 1.1 22.1 0.4 0.0 0.4 1.5 1.1 0.8 12.4 5.3 0.0 0.0 0.1 0.0 0.0 16.6 7.7 0.3 2.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.3 0.0 0.1 1.7 0.0 3.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 410.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 1.3 4.1 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.2 0.0 0.1 0.1 100.3 2.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.6 0.2 9.0 317.1 2.7 0.0 0.0 0.0 0.4 1.4 30.4 0.0 5.3 0.0 0.0 6.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 2.3 0.9 39.4 1.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 10.9 0.1 0.3 0.2 0.3 2.3 1.3 0.6 0.0 0.0 HAX1 "HAX-1, HCLSBP1, HS1BP1" ENSG00000143575 "HCLS1 associated protein X-1" O00165 1 154272589-154275875 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055141, HPA075289" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055141: AB_2682714, HPA075289: AB_2686742" "unprognostic (1.32e-1)" "unprognostic (2.68e-1)" "unprognostic (9.50e-2)" "unprognostic (6.93e-2)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (1.55e-3)" "unprognostic (2.34e-1)" "unprognostic (2.20e-1)" "unprognostic (9.09e-3)" "unprognostic (3.09e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.52e-1)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.96e-1)" 58.6 63.0 100.0 43.6 105.5 36.8 74.4 105.2 124.1 60.0 100.6 62.0 48.0 46.2 100.1 53.7 61.7 40.4 168.6 100.5 107.9 76.1 104.0 45.2 58.3 102.1 99.9 72.9 85.5 84.9 88.6 40.5 102.9 55.5 63.3 54.1 85.8 63.8 256.7 48.8 43.2 64.1 105.1 47.1 66.3 69.5 105.0 67.4 69.2 242.7 77.3 58.5 48.9 103.3 115.3 100.7 84.2 178.0 100.3 111.8 132.1 109.8 178.7 227.0 207.5 126.6 125.7 170.9 150.7 188.0 105.9 100.0 190.7 151.3 172.3 171.0 140.8 81.8 76.5 104.4 221.5 172.5 167.0 104.4 274.2 172.8 206.3 82.2 129.7 246.1 166.1 244.8 145.6 260.9 169.9 136.1 88.7 277.4 213.2 121.3 59.7 326.7 115.4 60.8 123.2 121.7 96.4 228.2 326.7 137.5 190.0 454.8 64.5 92.7 122.7 97.7 148.8 284.8 315.9 315.3 139.0 158.4 153.4 266.5 97.6 215.4 113.7 121.9 129.3 136.1 139.2 128.3 118.6 142.2 166.5 132.6 61.1 116.7 150.1 122.8 183.3 163.9 100.0 105.5 105.2 124.1 100.5 107.9 102.1 99.9 102.9 105.1 105.0 103.3 69.9 28.9 37.6 7.2 125.2 74.6 112.2 118.8 60.9 57.0 92.8 123.1 106.9 62.9 71.6 46.0 47.9 84.8 76.1 54.1 181.9 93.3 147.6 41.3 36.6 65.6 57.6 66.0 12.0 106.4 132.1 62.2 36.7 34.0 99.6 80.6 61.4 90.3 98.7 40.4 12.9 67.1 91.6 63.9 79.3 104.6 61.2 66.8 87.2 9.4 128.5 91.1 91.6 7.5 17.1 84.6 63.6 62.1 192.9 92.5 128.7 141.8 59.3 97.5 59.2 58.2 76.0 223.8 112.0 71.0 76.4 88.8 97.7 74.3 71.7 101.7 HCN2 "BCNG-2, BCNG2, HAC-1" ENSG00000099822 "Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2" Q9UL51 19 589881-617159 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 146.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 60.4;Horizontal cells: 40.4;Inhibitory neurons: 18.7;Oligodendrocytes: 62.1;Rod photoreceptor cells: 14.9" "Group enriched" "Detected in many" 6 "glioma: 8.7;melanoma: 5.7;renal cancer: 2.8;testis cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 29.9;HeLa: 15.8;MCF7: 28.4;U-138 MG: 20.2;U-87 MG: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (8.69e-2)" "unprognostic (3.97e-3)" "unprognostic (3.31e-4)" "unprognostic (1.44e-1)" "unprognostic (2.44e-1)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" "unprognostic (5.32e-2)" "unprognostic (1.19e-3)" "unprognostic (8.00e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (5.53e-4)" "unprognostic (9.72e-3)" 0.1 4.2 34.9 0.2 58.1 0.4 0.1 84.7 111.8 0.1 0.0 0.6 0.1 0.1 0.2 1.6 0.0 0.1 11.6 38.2 56.6 1.3 0.2 0.2 0.3 86.6 76.7 0.1 0.3 3.4 12.8 0.1 84.9 0.3 0.0 7.5 0.3 0.1 0.1 0.9 0.4 0.1 38.2 0.4 0.4 3.1 146.0 0.1 0.1 0.0 0.3 0.1 0.4 66.9 0.1 29.9 0.3 1.0 3.1 2.1 1.0 2.1 2.4 0.8 0.2 4.3 0.3 0.0 6.5 2.9 2.1 0.2 0.6 0.1 0.1 5.1 12.6 0.0 15.8 0.4 2.2 0.3 5.6 5.6 0.5 0.2 0.1 0.9 0.1 0.7 1.8 0.2 2.1 28.4 0.1 0.0 1.4 0.7 0.8 0.2 0.1 0.7 0.5 0.9 11.3 5.8 7.3 0.1 2.3 0.5 5.9 1.0 2.8 20.2 3.0 0.4 8.4 0.5 0.4 0.2 41.7 1.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 58.1 84.7 111.8 38.2 56.6 86.6 76.7 84.9 38.2 146.0 66.9 0.5 0.0 0.0 2.0 0.6 0.6 0.0 0.0 1.2 60.4 0.7 0.9 4.1 0.0 0.0 0.0 2.1 0.0 1.6 0.3 0.0 0.1 0.1 0.6 0.4 0.9 1.2 2.7 12.8 0.0 0.3 0.2 0.0 1.2 0.0 0.2 0.7 0.1 0.1 40.4 18.7 0.0 0.0 1.3 0.3 0.4 0.0 1.1 0.0 2.8 0.0 2.7 0.0 5.5 62.1 0.1 0.0 0.7 1.4 0.1 0.0 0.3 0.0 14.9 0.0 0.1 0.5 0.1 1.7 4.5 0.6 0.3 1.2 0.1 0.1 0.1 HDAC11 ENSG00000163517 "Histone deacetylase 11" Q96DB2 3 13479724-13506424 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 122.7" "Group enriched" "Detected in many" 6 "Early spermatids: 357.7;Late spermatids: 692.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 47.7;T-47d: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (5.22e-2)" "unprognostic (3.58e-2)" "unprognostic (1.83e-1)" "unprognostic (5.69e-3)" "unprognostic (1.76e-1)" "unprognostic (4.71e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (4.50e-2)" "unprognostic (5.67e-3)" "unprognostic (1.78e-2)" "unprognostic (9.87e-2)" "unprognostic (3.94e-1)" "prognostic favorable (7.88e-10)" "unprognostic (3.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.46e-1)" "unprognostic (1.39e-3)" 7.7 10.1 92.5 3.9 115.5 0.8 9.4 89.2 98.4 16.9 62.8 18.0 12.2 11.8 6.5 17.6 13.3 9.1 31.4 82.5 90.5 25.1 6.6 9.1 2.8 95.2 100.1 16.7 38.1 23.2 22.8 4.6 87.4 15.9 6.9 6.2 17.4 12.2 51.5 18.7 13.4 7.3 83.9 5.3 12.8 84.2 100.5 4.9 16.5 15.5 4.1 14.7 14.4 122.7 12.0 8.0 8.0 6.6 11.9 10.4 6.5 7.5 5.4 7.8 5.1 4.0 10.4 1.0 9.3 11.6 12.3 8.9 4.7 14.6 5.0 5.1 4.4 2.4 3.7 11.3 12.6 0.2 4.1 9.0 26.6 8.7 6.8 14.2 5.8 7.6 5.0 2.1 7.7 12.2 1.5 1.7 2.1 8.1 20.9 1.7 11.8 3.4 16.6 9.0 1.3 6.2 12.1 47.7 21.8 6.6 42.6 2.8 5.3 6.7 13.0 13.0 4.7 1.5 4.5 0.2 2.1 1.8 4.1 0.1 2.6 5.8 3.3 1.6 2.3 1.1 3.1 2.6 1.8 0.4 3.0 2.1 1.0 9.6 0.6 1.7 2.6 1.9 92.5 115.5 89.2 98.4 82.5 90.5 95.2 100.1 87.4 83.9 100.5 122.7 5.2 9.6 5.0 11.4 0.9 11.5 7.7 11.0 8.6 8.5 10.6 8.0 84.6 8.6 8.9 11.0 0.0 18.9 2.8 23.1 19.6 14.6 357.7 8.6 5.2 6.3 8.9 0.8 6.9 11.4 3.1 9.7 9.7 7.8 1.3 5.0 7.1 2.8 6.0 10.1 7.1 14.4 18.3 3.5 3.8 692.3 16.1 3.6 8.8 1.0 4.6 21.8 2.1 12.5 46.9 11.1 13.6 15.4 0.7 5.1 36.1 24.9 12.0 5.6 0.0 5.6 9.5 15.3 7.3 10.1 10.5 5.7 3.3 3.1 20.0 6.8 HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Ductal cells: 35.2;Extravillous trophoblasts: 42.2;Granulosa cells: 37.0;Hofbauer cells: 42.3;Proximal tubular cells: 41.1;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005548 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA005548: AB_1078497" "unprognostic (4.04e-2)" "unprognostic (5.04e-2)" "unprognostic (4.54e-3)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.04e-3)" "unprognostic (7.35e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (5.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (7.07e-3)" "unprognostic (1.71e-1)" "unprognostic (1.20e-2)" "unprognostic (7.21e-3)" 17.4 29.7 15.0 13.2 15.3 16.5 17.3 15.4 15.7 12.9 16.7 21.5 26.5 14.6 6.8 21.7 13.6 9.8 45.0 15.4 14.8 19.8 40.5 12.6 14.5 15.4 14.9 12.2 20.9 17.5 11.6 8.1 14.6 15.5 14.1 5.7 18.6 10.0 46.9 23.0 17.2 11.4 14.8 19.3 19.9 15.9 15.9 13.6 10.1 55.7 12.0 16.5 14.1 15.0 64.0 41.5 30.5 41.5 17.7 10.8 38.8 17.9 19.6 47.1 50.2 61.1 23.3 103.9 29.3 21.6 23.0 44.0 38.7 42.0 21.8 31.6 56.7 0.0 30.7 0.0 29.4 47.6 23.5 26.1 51.1 21.0 23.1 26.4 33.3 67.4 31.0 26.2 24.9 62.1 84.2 97.2 46.6 97.9 36.7 47.4 45.8 26.3 32.2 34.7 61.4 46.5 34.9 49.9 54.3 23.9 50.1 58.5 29.1 39.7 29.4 28.2 31.3 41.3 48.5 77.8 32.0 0.1 34.2 12.3 86.2 4.7 28.4 56.7 35.6 24.6 26.4 25.8 74.5 23.6 34.3 29.3 4.5 30.7 31.4 30.9 29.7 48.0 15.0 15.3 15.4 15.7 15.4 14.8 15.4 14.9 14.6 14.8 15.9 15.0 21.5 6.4 2.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 23.9 22.4 0.0 0.0 5.0 5.5 0.0 26.5 9.3 0.0 43.0 35.2 0.0 8.4 14.9 9.2 0.0 0.0 0.0 28.2 42.2 7.7 0.0 11.5 5.1 37.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.5 0.0 0.0 41.1 1.5 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 15.7 3.4 55.8 0.0 0.0 HEY2 "bHLHb32, HERP1, HESR2" ENSG00000135547 "Hes related family bHLH transcription factor with YRPW motif 2" Q9UBP5 6 125747664-125761269 "Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 30.7" "Cell type enhanced" "Detected in many" "Early spermatids: 49.9;Endometrial ciliated cells: 46.1;Granulosa cells: 73.9;Late spermatids: 80.6;Sertoli cells: 52.6;Smooth muscle cells: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.5;HEK 293: 7.1;SK-MEL-30: 6.6;TIME: 14.8;U-266/70: 17.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030205, HPA074851" Approved Approved "Nuclear bodies,Aggresome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" Aggresome "HPA030205: AB_10600712, HPA074851: AB_2686718" "unprognostic (5.10e-2)" "unprognostic (4.34e-2)" "unprognostic (1.41e-3)" "unprognostic (2.43e-3)" "unprognostic (1.99e-1)" "unprognostic (2.52e-3)" "unprognostic (2.56e-1)" "unprognostic (1.38e-2)" "unprognostic (2.01e-1)" "unprognostic (9.10e-3)" "unprognostic (7.34e-2)" "unprognostic (6.20e-2)" "unprognostic (1.79e-1)" "unprognostic (2.28e-1)" "unprognostic (6.74e-2)" "unprognostic (1.51e-3)" "unprognostic (1.19e-1)" 6.5 0.9 8.8 1.0 12.0 0.1 5.7 9.4 7.6 8.0 3.0 2.5 1.3 7.5 16.4 1.8 13.5 1.7 30.7 7.2 10.4 3.1 5.3 3.2 0.5 12.7 10.0 7.1 3.3 2.6 5.5 3.7 10.6 2.1 1.3 5.7 2.0 2.7 16.2 2.4 2.1 1.7 14.1 1.9 2.0 6.6 11.8 0.7 3.1 4.9 0.6 2.7 4.7 12.2 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.8 0.2 0.2 0.1 0.0 0.5 7.1 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.6 0.0 0.4 0.0 0.0 3.2 0.0 0.3 0.5 0.6 0.9 0.0 0.1 2.3 0.0 0.0 0.0 6.6 3.2 1.9 0.0 14.8 0.3 0.0 0.1 0.8 17.6 0.3 0.1 0.6 0.0 2.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.8 12.0 9.4 7.6 7.2 10.4 12.7 10.0 10.6 14.1 11.8 12.2 2.8 3.2 1.1 12.4 0.7 3.8 0.5 8.7 3.4 0.4 9.8 5.7 21.5 0.0 2.7 0.0 8.4 0.0 1.4 0.1 9.8 0.1 49.9 46.1 4.2 6.0 0.0 2.7 0.1 1.8 0.1 3.3 1.1 36.8 0.0 73.9 1.8 8.0 0.1 1.7 0.4 0.0 2.0 0.8 3.0 80.6 6.5 0.6 3.6 5.6 0.0 34.8 3.1 2.5 23.4 1.1 0.1 23.3 3.1 0.3 0.0 6.4 5.4 5.2 52.6 17.5 41.8 16.2 15.1 7.7 2.0 0.0 2.0 2.8 0.1 0.3 HIBADH NS5ATP1 ENSG00000106049 "3-hydroxyisobutyrate dehydrogenase" P31937 7 27525442-27662883 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 543.9;Proximal tubular cells: 355.1;Syncytiotrophoblasts: 272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019522, HPA021002" Enhanced NA NA 820000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA019522: AB_1850690, HPA021002: AB_1850692" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "unprognostic (7.50e-2)" "unprognostic (9.79e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-3)" "unprognostic (7.22e-3)" "unprognostic (3.14e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "prognostic favorable (5.56e-11)" "unprognostic (2.49e-2)" "unprognostic (5.47e-2)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" 62.1 79.0 15.0 11.9 18.0 7.6 56.5 18.8 18.4 37.2 27.6 33.8 35.0 35.3 11.6 20.4 41.6 28.4 66.7 13.2 18.2 160.5 197.9 20.4 15.1 16.1 17.0 33.4 34.2 97.4 14.1 47.4 16.9 44.7 34.5 31.5 45.4 42.4 117.4 13.1 32.0 37.2 15.6 18.0 34.0 26.4 17.4 21.2 54.5 203.2 14.8 33.5 18.0 17.5 74.0 46.8 31.0 50.1 89.1 109.8 29.3 44.8 83.8 46.3 52.8 27.6 85.2 29.9 38.4 81.4 79.4 67.1 34.5 66.5 67.3 20.9 34.6 14.6 73.0 114.3 73.8 22.4 16.1 101.2 54.1 34.8 120.6 112.1 61.7 35.3 59.7 29.2 117.2 31.2 21.4 34.7 30.0 110.4 56.0 21.2 31.2 33.1 106.5 43.6 28.6 31.7 93.8 173.5 77.9 76.4 75.0 48.6 40.3 28.6 49.5 47.1 31.2 51.8 39.7 17.8 41.2 67.8 85.1 5.3 17.3 8.2 16.7 22.8 22.5 18.2 18.4 19.3 19.3 16.4 24.0 19.8 3.0 22.9 22.0 9.1 13.2 17.4 15.0 18.0 18.8 18.4 13.2 18.2 16.1 17.0 16.9 15.6 17.4 17.5 17.3 9.6 6.4 56.2 14.1 21.3 43.6 51.9 17.1 15.8 58.8 28.2 105.8 58.6 37.7 47.8 4.2 181.1 8.1 23.3 543.9 35.8 58.5 22.8 28.5 21.5 15.6 33.2 64.4 29.1 138.9 44.6 43.3 27.3 2.5 12.0 25.4 149.8 53.7 23.5 85.9 28.9 40.7 28.3 10.0 62.3 44.7 18.5 65.8 51.5 11.0 34.1 8.2 147.2 131.6 28.0 24.1 36.9 20.1 46.1 58.4 355.1 50.8 11.9 46.0 31.6 35.4 35.0 44.3 22.4 15.5 272.4 15.2 77.3 38.8 47.3 HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 32: Non-specific - Translation" Mitochondria Cytosol "HPA042715: AB_2678127" "unprognostic (9.24e-2)" "unprognostic (6.31e-3)" "unprognostic (7.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (1.98e-2)" "unprognostic (3.11e-3)" "unprognostic (9.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.09e-2)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" 146.1 175.6 143.3 87.0 146.2 133.1 113.5 147.2 175.0 104.7 168.0 199.4 118.9 111.7 51.3 130.0 105.0 80.5 318.7 139.8 146.0 182.7 163.3 95.7 132.9 143.9 142.2 118.7 108.7 204.9 125.1 54.6 141.6 127.9 96.3 45.5 163.2 92.7 422.5 140.8 136.6 68.1 145.3 129.3 148.6 66.0 149.0 110.7 114.0 297.9 92.7 152.3 105.2 145.7 104.9 166.6 99.0 172.6 98.5 186.4 262.2 66.6 109.7 164.7 206.4 176.0 202.2 183.3 149.9 107.1 214.2 127.3 146.2 260.6 65.9 424.0 234.0 92.6 161.7 244.7 137.4 149.7 230.1 238.2 213.2 93.7 113.3 126.3 141.7 146.5 104.0 341.5 124.0 315.9 165.3 178.1 124.8 195.5 181.7 157.1 75.6 324.7 265.5 158.7 107.9 141.5 71.4 295.2 310.5 100.7 173.3 233.7 96.8 118.5 124.7 110.2 142.5 165.2 216.6 158.4 150.5 254.1 77.5 284.2 743.6 219.8 391.2 975.8 389.5 618.1 540.1 452.6 930.0 496.0 488.1 464.2 124.6 308.0 1024.9 616.8 621.8 971.3 143.3 146.2 147.2 175.0 139.8 146.0 143.9 142.2 141.6 145.3 149.0 145.7 100.4 73.7 78.6 0.0 212.5 232.2 332.8 358.0 272.0 60.5 225.5 288.5 145.3 174.5 191.0 182.1 12.5 223.0 184.2 415.6 534.1 204.5 83.9 140.0 120.6 110.9 266.6 90.8 0.0 237.3 185.4 129.1 142.2 124.2 130.0 157.0 120.3 217.0 378.7 65.6 0.0 450.7 219.7 458.8 345.2 56.8 140.1 292.1 257.9 0.0 449.7 138.1 230.7 0.0 0.0 110.0 493.0 85.0 184.2 292.6 313.8 542.8 142.3 47.7 118.3 145.9 138.8 96.7 79.4 301.8 225.0 280.2 223.7 182.1 385.3 532.4 HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 633.9;Hepatocytes: 457.4;Proximal tubular cells: 578.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" 50.8 79.5 41.7 15.5 43.9 27.0 48.5 44.9 46.8 23.2 40.3 42.6 34.9 25.9 48.6 27.5 29.9 14.9 87.4 39.8 43.1 91.1 169.2 30.2 21.0 43.8 42.5 19.2 65.9 72.6 41.2 17.6 42.0 33.9 34.2 20.4 39.7 26.1 80.1 33.4 34.2 20.1 43.9 33.8 56.9 29.8 47.3 38.8 38.4 85.5 23.8 30.6 24.2 44.0 30.3 76.1 47.1 45.6 29.0 24.3 33.2 27.8 39.2 42.3 46.1 49.9 31.1 39.9 31.7 25.3 59.8 29.3 21.2 40.9 44.1 87.8 40.7 42.2 64.1 45.8 68.1 25.1 40.0 27.3 36.8 40.2 64.8 16.7 33.2 91.4 25.5 117.4 34.0 60.3 61.3 31.3 21.4 70.0 138.7 60.8 33.1 53.6 61.5 21.5 38.4 46.4 36.0 42.7 49.6 27.5 45.9 44.6 16.5 22.0 37.7 30.4 35.7 107.0 127.3 57.4 49.8 32.2 36.2 41.0 77.5 4.7 68.9 58.5 62.4 98.9 73.7 69.8 113.4 96.7 56.4 58.6 7.6 66.8 56.9 246.1 107.3 81.2 41.7 43.9 44.9 46.8 39.8 43.1 43.8 42.5 42.0 43.9 47.3 44.0 49.3 22.4 17.5 5.2 57.9 45.4 63.4 137.6 49.5 39.8 99.1 105.8 115.1 130.1 68.3 80.9 20.9 154.9 69.3 148.2 633.9 115.5 67.3 83.9 28.6 47.8 96.0 100.8 1.7 172.1 71.7 53.2 52.5 44.6 18.4 43.5 63.1 457.4 113.9 20.2 2.5 127.4 126.1 61.1 51.4 128.0 40.4 47.7 120.9 1.9 74.1 123.7 87.6 1.5 4.5 85.6 157.5 44.8 77.7 40.7 181.4 578.1 105.1 45.5 46.0 54.2 72.6 38.4 77.4 64.7 45.9 56.8 51.0 85.1 126.7 84.8 HIPK4 FLJ32818 ENSG00000160396 "Homeodomain interacting protein kinase 4" Q8NE63 19 40379271-40390181 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 7.7;testis: 18.1" "Group enriched" "Detected in some" 6 "Early spermatids: 101.4;Late spermatids: 32.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 7.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.07e-2)" "unprognostic (6.25e-2)" "unprognostic (2.58e-2)" "unprognostic (5.53e-3)" "unprognostic (4.00e-2)" "unprognostic (1.36e-1)" "unprognostic (3.69e-2)" "unprognostic (2.52e-3)" "unprognostic (1.08e-1)" "unprognostic (7.48e-3)" "unprognostic (8.85e-2)" "unprognostic (9.09e-2)" "unprognostic (3.06e-2)" "unprognostic (8.71e-3)" "unprognostic (3.64e-2)" "unprognostic (2.03e-2)" "unprognostic (4.63e-2)" 0.2 0.1 1.3 0.0 7.7 0.0 0.2 1.1 3.6 0.3 0.0 0.5 0.0 0.4 0.0 0.2 0.2 0.0 0.4 5.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.1 18.1 0.3 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 7.7 1.1 3.6 5.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.7 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 101.4 0.1 0.3 0.6 0.0 0.0 8.4 0.0 0.0 0.6 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.7 32.9 1.5 0.3 0.0 1.9 0.0 0.0 1.0 0.0 0.5 0.1 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.0 0.0 4.2 0.7 10.3 0.5 1.1 0.3 0.0 0.1 0.2 0.0 0.1 HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 122.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.7;Excitatory neurons: 77.5;Hepatocytes: 156.8;Horizontal cells: 92.5;Microglial cells: 74.0" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Region enhanced" "Detected in many" "cerebral cortex: 53.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 163.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA068156: AB_2685963, HPA071210: AB_2686361" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "prognostic favorable (1.88e-4)" "unprognostic (5.30e-3)" "prognostic favorable (2.71e-7)" "unprognostic (1.42e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-3)" "unprognostic (2.19e-1)" "prognostic favorable (3.55e-6)" "unprognostic (8.47e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (1.60e-2)" 15.1 21.5 9.8 1.9 23.1 0.4 15.4 0.0 53.3 14.4 0.0 18.0 1.4 14.4 11.0 26.3 12.2 7.8 24.1 17.6 0.0 12.7 122.4 13.4 2.2 0.0 0.6 50.0 2.9 4.0 9.9 1.0 0.0 13.2 3.4 43.2 24.1 12.4 7.7 16.7 4.3 12.3 0.0 8.2 6.1 4.1 3.9 3.4 34.3 9.9 7.7 12.3 7.8 17.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.9 0.5 0.0 0.0 0.0 0.4 0.2 0.0 27.3 0.7 0.0 0.1 163.0 0.1 0.9 0.2 0.1 0.7 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.6 1.1 0.0 0.1 0.0 2.4 0.0 0.4 0.4 13.0 0.1 11.1 0.6 0.0 7.2 0.2 0.0 0.2 0.0 0.1 0.8 0.2 0.6 0.5 5.1 4.9 0.0 0.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 23.1 0.0 53.3 17.6 0.0 0.0 0.6 0.0 0.0 3.9 17.2 13.8 3.2 42.8 22.2 0.4 22.3 4.4 1.4 56.9 120.7 5.9 16.4 38.6 12.8 6.3 7.3 10.4 0.1 0.5 0.0 11.7 1.9 1.3 0.1 6.2 19.7 3.0 0.8 77.5 0.9 0.0 17.6 0.0 0.6 0.0 0.5 6.1 156.8 0.1 92.5 36.6 0.6 0.0 3.5 4.0 4.7 28.3 0.7 10.6 74.0 0.1 60.7 0.0 24.6 6.9 0.4 0.0 39.1 1.5 1.3 2.8 23.3 1.0 15.0 13.1 4.5 7.4 0.4 5.0 33.7 27.6 1.2 3.8 0.5 0.4 0.4 HMGCL HL ENSG00000117305 "3-hydroxy-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 322.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.4;Proximal tubular cells: 216.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favorable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favorable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" 27.5 63.0 26.3 16.8 27.5 7.5 25.8 27.5 28.3 27.5 33.0 53.3 45.7 20.2 47.2 32.8 35.6 26.3 42.5 24.6 26.9 115.5 322.5 23.6 21.7 28.0 26.2 21.6 33.4 60.2 26.3 19.9 27.7 31.7 52.9 16.1 30.3 27.9 63.7 25.5 40.0 23.3 27.4 26.8 40.9 17.9 30.1 23.4 40.5 70.2 25.1 28.6 24.2 29.6 28.5 16.0 17.7 13.4 70.6 53.5 6.8 22.0 38.3 23.3 28.2 10.2 53.7 14.8 44.3 34.6 19.0 22.4 21.3 35.7 25.2 30.4 16.1 19.8 13.8 23.5 90.9 7.8 12.7 62.4 52.0 30.8 58.5 62.5 32.2 27.4 20.6 20.3 43.3 29.3 12.2 15.3 4.6 77.4 22.1 17.2 14.5 27.9 55.4 14.5 14.8 13.2 28.6 10.8 49.3 23.3 33.9 19.3 24.3 19.3 11.6 35.5 9.7 28.7 15.2 13.3 47.7 28.7 23.0 103.5 67.0 66.0 36.3 66.0 39.8 45.9 39.1 42.1 58.0 51.2 39.6 37.7 25.5 54.4 77.5 43.9 45.5 61.7 26.3 27.5 27.5 28.3 24.6 26.9 28.0 26.2 27.7 27.4 30.1 29.6 19.9 12.8 25.7 14.0 16.3 5.9 29.9 54.3 9.6 24.6 19.9 17.1 33.7 41.5 30.6 49.7 18.8 43.0 10.0 48.1 119.3 57.7 2.3 25.0 17.5 22.5 9.0 18.7 4.3 24.0 27.3 20.8 30.5 23.1 17.7 29.7 30.4 172.4 61.6 35.3 5.3 49.5 28.5 23.5 7.7 3.6 21.8 23.5 21.4 8.4 41.4 37.1 24.7 6.0 12.5 31.2 53.8 24.5 8.3 29.4 70.9 216.8 31.5 25.5 6.6 17.1 21.6 6.6 5.4 13.8 6.5 41.3 15.2 65.6 48.9 24.3 HMGN3 TRIP7 ENSG00000118418 "High mobility group nucleosomal binding domain 3" Q15651 6 79201245-79234738 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018370, HPA027971, HPA063572" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Cytosol "CAB018370: , HPA027971: AB_1850808, HPA063572: AB_2732703" "unprognostic (1.02e-1)" "unprognostic (2.04e-2)" "unprognostic (5.92e-2)" "unprognostic (5.26e-2)" "unprognostic (3.48e-1)" "unprognostic (3.88e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.76e-4)" "unprognostic (8.78e-2)" "unprognostic (5.31e-3)" "unprognostic (1.47e-3)" "unprognostic (5.81e-2)" "prognostic unfavorable (1.02e-7)" "unprognostic (1.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.69e-1)" "unprognostic (6.43e-3)" 92.4 174.4 132.9 69.5 136.2 72.8 116.1 141.8 190.4 82.2 153.6 100.6 90.4 93.6 168.6 95.1 209.3 82.8 227.2 132.9 135.8 168.4 147.5 111.5 127.1 139.5 135.2 105.5 90.3 116.7 152.0 114.6 140.8 84.7 73.4 164.6 154.3 68.0 151.4 81.1 74.1 76.1 136.6 91.5 106.9 83.2 133.7 112.7 113.2 130.1 109.9 77.1 81.9 145.6 101.7 90.3 309.7 135.0 121.9 99.6 70.1 69.0 73.7 75.6 110.3 508.3 83.9 1.2 124.2 56.5 101.0 63.4 203.6 78.3 74.2 298.7 170.9 355.9 292.3 268.9 78.0 294.9 52.3 121.5 85.4 50.3 27.7 72.9 170.9 74.3 212.3 275.0 123.8 92.9 136.3 564.7 227.8 87.7 224.5 229.7 472.6 103.8 525.3 145.3 126.0 168.5 131.3 149.4 102.4 271.1 85.1 488.6 75.0 20.9 91.7 73.5 155.3 235.3 375.2 1.9 11.8 1.1 103.0 38.3 147.3 13.6 107.8 148.0 95.9 112.9 75.7 92.8 179.2 99.8 88.7 106.8 7.2 142.3 143.9 208.6 90.4 169.3 132.9 136.2 141.8 190.4 132.9 135.8 139.5 135.2 140.8 136.6 133.7 145.6 140.6 96.1 167.9 129.9 110.1 171.1 193.7 516.8 234.5 261.8 301.4 376.3 424.5 231.6 373.7 242.8 75.0 940.6 169.9 35.3 602.6 229.3 72.5 775.8 108.1 166.0 272.9 95.4 115.8 198.6 823.7 165.3 116.2 199.2 109.6 80.9 261.3 256.3 309.7 195.2 105.3 131.1 435.4 186.0 206.5 60.9 187.0 148.4 257.9 58.1 403.3 320.2 198.8 66.9 159.7 107.2 52.4 167.0 211.3 85.3 36.5 852.5 900.3 134.3 144.7 102.4 233.9 26.8 52.0 260.0 149.9 555.3 109.9 232.4 121.5 173.2 HOMER1 "HOMER-1B, SYN47, Ves-1" ENSG00000152413 "Homer scaffold protein 1" Q86YM7 5 79372636-79514134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;skeletal muscle: 34.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 440.0;Inhibitory neurons: 112.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004437, HPA036521, HPA036522" Enhanced Supported Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB004437: AB_627742, HPA036521: AB_2675170, HPA036522: AB_2675171" "unprognostic (2.80e-1)" "unprognostic (5.30e-2)" "unprognostic (4.00e-2)" "unprognostic (5.79e-2)" "unprognostic (8.83e-2)" "unprognostic (6.40e-2)" "unprognostic (2.00e-3)" "unprognostic (2.41e-3)" "unprognostic (2.22e-1)" "unprognostic (3.79e-1)" "unprognostic (3.07e-3)" "unprognostic (3.98e-1)" "unprognostic (7.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (2.83e-2)" "unprognostic (2.86e-3)" 2.8 1.3 2.1 2.3 14.0 0.3 2.5 10.6 27.6 3.9 0.0 1.2 0.7 6.7 4.1 4.6 1.7 6.8 20.5 17.9 5.6 5.8 1.7 5.1 1.1 0.0 3.3 3.8 2.2 4.1 2.3 5.4 2.2 1.7 1.0 5.8 1.2 1.7 34.0 2.4 0.8 4.7 0.6 0.8 2.0 5.3 7.4 1.3 15.0 12.9 1.4 8.0 1.7 15.1 14.6 9.8 14.5 23.1 5.4 3.6 33.5 9.0 7.2 9.0 9.6 15.5 9.9 0.2 26.9 7.8 16.2 7.7 18.2 24.5 15.4 2.2 14.3 17.3 3.9 15.7 8.8 8.3 5.4 5.8 15.4 8.1 22.4 3.6 4.3 26.4 21.7 9.3 11.7 20.4 34.8 5.7 24.5 5.2 8.4 22.4 23.8 22.2 9.6 22.3 14.7 8.8 17.2 12.0 9.3 16.0 16.5 7.2 0.7 6.6 16.7 8.0 16.1 4.5 10.8 8.5 18.8 3.3 13.0 0.0 0.0 0.0 0.4 0.0 0.2 0.4 0.1 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.1 2.1 14.0 10.6 27.6 17.9 5.6 0.0 3.3 2.2 0.6 7.4 15.1 4.3 51.3 9.6 21.9 12.1 64.2 28.0 8.5 20.5 24.4 25.6 18.2 95.2 7.2 12.1 16.5 27.1 58.4 20.3 4.3 11.7 4.8 4.7 30.6 24.9 9.5 11.4 0.4 440.0 4.3 44.8 19.3 5.6 39.9 5.7 16.9 4.6 6.9 11.9 52.2 112.1 7.5 10.2 9.6 29.7 5.5 5.6 13.9 21.4 31.9 3.0 4.4 8.2 86.0 19.3 5.5 2.7 8.6 8.9 23.3 3.1 7.0 10.8 8.1 13.1 29.7 19.3 6.9 10.3 23.9 54.8 84.4 9.8 10.2 3.0 25.2 HPCAL4 "DKFZp761G122, HLP4" ENSG00000116983 "Hippocalcin like 4" Q9UM19 1 39678648-39691485 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 91.2" "Group enriched" "Detected in some" 4 "Bipolar cells: 39.2;Distal tubular cells: 11.7;Excitatory neurons: 16.4;Inhibitory neurons: 20.0" "Group enriched" "Detected in some" 11 "glioma: 5.4;thyroid cancer: 4.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 3.0;naive CD4 T-cell: 2.6" "Lineage enriched" "Detected in single" 30 "T-cells: 3.0" "Cell line enhanced" "Detected in some" "Karpas-707: 2.7;SH-SY5Y: 9.1;SK-MEL-30: 2.9;U-2 OS: 1.9;U-266/70: 2.4;U-266/84: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA053808: AB_2682270" "unprognostic (2.62e-1)" "unprognostic (2.37e-1)" "unprognostic (2.13e-2)" "unprognostic (8.56e-4)" "unprognostic (4.73e-3)" "unprognostic (1.99e-1)" "unprognostic (7.57e-2)" "unprognostic (4.89e-3)" "unprognostic (1.27e-1)" "unprognostic (3.18e-2)" "unprognostic (4.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.62e-3)" "unprognostic (3.78e-3)" "unprognostic (2.77e-2)" "unprognostic (3.97e-2)" "unprognostic (2.63e-1)" 0.0 10.1 75.1 0.8 89.6 0.4 0.0 38.1 89.3 0.0 0.0 0.3 0.2 0.0 0.3 5.2 0.0 0.2 1.1 91.2 38.0 4.7 0.0 0.6 1.0 16.8 29.8 2.9 4.9 0.2 2.1 0.0 30.1 0.3 0.1 10.9 0.1 0.1 3.2 0.1 0.4 0.0 28.1 0.3 0.6 4.6 58.1 0.2 0.1 1.2 0.8 0.1 0.1 43.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 1.4 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.8 9.1 0.2 0.0 2.9 0.1 0.0 0.1 0.0 0.0 1.9 0.0 0.0 2.4 3.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 3.0 0.5 0.1 0.0 2.6 0.9 0.0 0.0 0.0 0.0 2.2 0.9 75.1 89.6 38.1 89.3 91.2 38.0 16.8 29.8 30.1 28.1 58.1 43.8 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 39.2 0.1 0.1 1.5 0.0 0.6 1.8 0.0 0.0 0.0 0.0 11.7 0.0 3.4 0.1 0.0 0.1 0.0 0.0 16.4 0.8 0.0 0.6 0.0 0.7 0.0 0.2 0.0 0.0 0.0 1.7 20.0 0.0 0.0 0.0 0.0 1.2 1.2 0.1 0.0 1.0 0.0 4.9 0.0 1.5 1.3 0.2 0.0 1.5 0.3 0.0 0.0 0.1 0.0 1.4 0.0 0.3 0.1 2.8 0.7 0.0 0.0 0.0 0.9 0.1 0.0 0.0 HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204655-33206831 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 125.2;Proximal tubular cells: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 79.5;T-47d: 62.0;U-266/70: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced NA NA 97000 "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA042132: AB_10793978" "prognostic favorable (9.99e-4)" "unprognostic (4.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.11e-2)" "prognostic favorable (1.90e-5)" "unprognostic (1.50e-3)" "unprognostic (3.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "prognostic favorable (2.18e-12)" "unprognostic (2.82e-2)" "unprognostic (5.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.23e-2)" 9.6 24.6 10.1 6.5 10.5 9.7 17.0 9.9 11.3 13.7 10.9 18.0 19.7 7.2 29.4 25.5 23.6 7.9 20.3 9.6 10.8 30.7 67.4 11.2 10.5 11.3 11.9 8.6 55.3 42.2 14.1 5.6 12.3 11.3 16.2 11.8 25.1 16.5 20.8 25.9 18.8 7.3 11.4 12.1 15.1 5.9 10.8 13.3 32.9 25.0 15.1 9.8 12.8 11.3 7.0 15.0 6.8 9.3 2.3 4.4 1.3 0.8 4.7 0.1 0.1 5.8 17.5 45.4 11.2 1.2 2.2 29.1 7.2 11.7 1.0 8.6 0.0 2.6 14.0 27.1 20.0 0.0 3.8 5.0 28.9 0.2 49.4 0.4 2.1 13.6 0.3 46.2 4.1 9.4 31.2 1.3 2.1 23.3 2.9 11.0 1.2 79.5 27.8 1.3 12.1 7.6 2.9 34.3 7.6 4.6 62.0 1.8 1.3 0.7 7.3 0.6 0.4 65.5 42.4 16.6 3.1 1.0 1.7 0.1 5.8 2.0 18.7 13.4 30.0 16.6 24.0 29.2 11.6 13.1 26.4 28.5 0.7 16.8 14.6 20.8 21.8 26.7 10.1 10.5 9.9 11.3 9.6 10.8 11.3 11.9 12.3 11.4 10.8 11.3 12.5 19.2 21.6 3.3 18.6 29.7 28.3 55.0 21.6 12.4 31.3 34.8 31.8 48.6 25.9 22.0 6.2 29.9 9.7 21.2 125.2 27.9 6.3 20.0 6.0 10.1 18.0 12.8 0.3 32.4 12.9 9.1 16.3 13.7 7.0 9.8 10.0 83.2 17.4 1.7 0.5 26.6 20.3 10.3 16.4 18.1 7.5 7.9 49.8 1.0 8.1 32.6 6.2 1.0 0.7 21.9 21.1 6.0 47.6 15.4 74.8 137.2 33.3 14.8 0.0 11.3 9.8 8.1 8.5 40.0 37.2 17.4 18.0 29.8 44.4 31.5 HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 181.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 214.8;Early spermatids: 153.9;Granulosa cells: 187.2;Late spermatids: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA042890: AB_2678216, HPA050453: AB_2681131" "unprognostic (3.17e-3)" "unprognostic (1.62e-2)" "unprognostic (1.90e-3)" "prognostic favorable (9.23e-6)" "unprognostic (3.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.82e-1)" "prognostic favorable (9.29e-7)" "unprognostic (1.44e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (7.35e-2)" 76.3 63.6 28.1 13.3 30.1 11.6 22.8 25.1 29.5 23.3 27.6 31.7 38.9 22.8 11.5 29.8 21.2 19.0 89.9 24.8 33.1 69.0 149.0 28.7 13.9 25.4 33.2 50.8 20.0 21.8 8.8 16.8 27.1 20.3 26.9 12.6 18.8 15.9 151.7 31.1 32.2 20.5 26.6 18.6 24.6 14.0 32.0 19.6 30.4 181.3 15.8 29.2 15.0 28.5 45.0 39.4 29.0 14.8 49.0 48.4 33.4 30.1 18.6 21.1 17.7 77.0 49.4 28.5 16.2 44.4 26.9 50.6 31.9 42.2 25.8 120.9 21.0 30.0 58.5 76.1 30.7 17.1 18.5 52.0 29.9 31.3 22.8 30.5 24.8 34.7 42.3 18.9 58.2 29.6 42.5 15.3 17.2 106.9 50.3 27.1 87.4 42.7 44.5 40.4 20.7 14.5 75.8 49.5 26.0 23.7 70.0 20.0 28.3 30.2 27.9 85.2 29.6 21.5 57.3 13.5 37.0 24.8 18.2 54.3 8.4 32.8 4.6 8.1 6.8 6.9 4.8 5.0 9.5 8.4 5.6 5.9 48.0 5.9 11.5 9.4 8.7 4.9 28.1 30.1 25.1 29.5 24.8 33.1 25.4 33.2 27.1 26.6 32.0 28.5 32.0 99.3 84.3 48.6 14.1 13.3 17.5 21.6 29.6 9.3 12.0 13.3 214.8 14.3 32.2 14.7 6.2 26.5 18.3 23.7 64.6 15.5 153.9 38.6 38.3 19.1 14.9 32.8 10.8 18.7 30.9 31.1 29.0 27.8 30.4 187.2 17.2 124.2 35.7 6.7 12.2 32.2 8.2 23.6 12.5 163.0 27.4 27.5 8.8 15.9 47.3 24.1 6.2 16.1 19.3 13.2 23.5 47.0 20.9 16.0 52.4 111.1 37.7 14.5 46.0 18.1 46.9 12.9 16.4 34.2 16.2 31.7 16.2 108.9 36.2 29.5 HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 201.6;lymphoid tissue: 95.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Hepatic stellate cells: 33.2;Hepatocytes: 137.1;Proximal tubular cells: 58.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 100.9;SK-BR-3: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 590000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 11.4 21.5 5.0 2.8 4.5 0.3 9.2 6.4 6.3 10.8 18.3 6.8 3.4 8.2 0.8 5.5 7.3 13.2 68.2 4.5 4.0 49.4 201.6 30.7 1.8 5.4 4.8 3.0 9.4 19.9 3.3 2.4 5.6 4.6 2.9 3.1 7.3 2.9 15.0 21.1 6.0 5.9 3.5 95.1 19.4 1.7 5.8 0.8 8.3 19.0 1.2 4.8 12.3 4.7 2.9 1.8 0.4 0.9 0.6 0.7 0.5 0.1 0.3 0.1 0.4 11.4 3.1 0.0 0.8 0.6 0.6 6.6 0.2 0.4 0.0 0.1 0.0 0.3 8.6 100.9 4.4 0.7 0.7 3.9 13.8 0.1 0.4 0.8 2.9 0.3 0.3 0.5 0.4 0.6 0.1 0.3 0.6 7.1 0.6 0.0 0.2 0.3 5.9 0.4 0.2 2.1 0.2 28.0 0.3 2.4 2.0 0.3 1.9 0.6 0.6 0.6 0.3 0.2 0.3 0.4 0.4 0.6 0.3 1.3 0.4 1.5 0.3 0.1 0.8 0.4 0.3 0.4 0.2 0.5 0.6 0.4 3.1 0.3 0.3 0.5 0.4 0.1 5.0 4.5 6.4 6.3 4.5 4.0 5.4 4.8 5.6 3.5 5.8 4.7 18.1 19.2 18.5 1.6 0.3 2.9 0.4 3.3 0.0 1.0 0.3 0.1 20.8 30.0 2.0 11.0 4.2 0.1 0.0 2.5 23.5 16.5 8.2 0.2 0.9 25.8 1.8 2.7 3.1 14.4 0.1 3.3 19.4 0.2 0.0 0.6 33.2 137.1 0.1 0.0 3.1 1.4 0.0 4.4 0.9 7.7 2.1 0.9 0.0 7.5 0.0 0.4 0.0 1.5 1.6 12.1 0.3 1.2 0.0 0.2 0.4 58.2 0.9 0.5 6.6 1.2 4.3 0.4 1.1 0.9 3.1 0.7 0.9 7.4 0.9 1.7 IDH3B RP46 ENSG00000101365 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta" O43837 20 2658395-2664219 "Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049387, HPA054180" Supported Enhanced Mitochondria NA NA 8300 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA049387: AB_2680740, HPA054180: AB_2682407" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.12e-1)" "unprognostic (2.43e-2)" "unprognostic (3.24e-2)" "unprognostic (6.83e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.76e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-2)" "unprognostic (4.75e-3)" "unprognostic (1.39e-2)" "prognostic favorable (6.78e-8)" "unprognostic (8.89e-2)" "unprognostic (4.02e-2)" "unprognostic (2.79e-1)" "unprognostic (1.16e-1)" 55.6 61.3 51.8 33.4 53.0 57.9 54.7 60.8 57.9 56.6 49.4 70.8 73.9 57.3 35.9 62.4 49.8 29.6 185.8 53.8 56.3 71.0 60.5 43.9 41.9 58.0 54.0 57.7 46.0 75.3 36.8 41.1 60.0 45.7 59.7 46.1 49.1 43.1 204.0 61.9 59.9 44.7 50.6 53.1 63.7 36.6 56.6 59.5 49.4 236.6 56.5 55.5 53.4 56.0 111.6 147.4 66.0 57.9 71.3 55.9 76.0 58.2 74.0 134.5 106.7 191.4 113.4 124.5 52.2 80.4 123.7 152.7 122.9 189.0 122.6 34.7 96.7 151.2 58.4 200.6 69.7 166.5 31.8 74.4 71.5 125.9 65.7 59.2 80.4 105.6 194.9 67.7 83.0 61.1 146.1 190.4 128.3 113.4 137.9 117.7 120.2 140.2 77.7 102.5 118.5 85.5 71.9 235.0 127.3 50.8 118.1 73.0 72.4 104.2 65.4 35.8 136.3 91.2 225.3 129.8 49.1 169.9 101.2 76.0 111.7 72.2 84.9 120.8 64.5 96.3 72.8 77.7 131.9 84.6 84.6 73.1 31.4 84.8 110.9 61.2 108.1 102.1 51.8 53.0 60.8 57.9 53.8 56.3 58.0 54.0 60.0 50.6 56.6 56.0 50.7 38.5 28.2 10.4 52.1 56.7 60.2 103.8 48.9 37.9 38.5 38.2 186.0 52.9 49.5 23.9 33.3 133.9 71.3 81.7 156.5 88.5 59.3 28.2 36.0 53.7 50.7 41.6 7.0 102.1 86.3 49.2 37.2 35.9 48.2 54.1 41.7 55.4 97.6 13.5 7.6 68.4 71.2 57.7 60.9 115.1 45.1 51.7 69.4 10.3 78.7 49.3 56.7 6.6 8.9 70.8 72.5 47.4 38.1 37.5 121.7 174.9 33.4 33.4 78.9 50.0 64.1 52.8 55.3 48.4 60.0 108.5 49.1 63.4 113.7 54.3 IDH3G ENSG00000067829 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma" P51553 X 153785766-153794523 "Citric acid cycle related proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 284.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000425, HPA002017" Supported Approved Nucleoli,Mitochondria Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" "HPA000425: AB_1079097, HPA002017: AB_1079096" "unprognostic (4.24e-2)" "unprognostic (1.43e-3)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (6.57e-2)" "unprognostic (2.25e-1)" "unprognostic (4.35e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (1.59e-2)" "unprognostic (2.81e-2)" "unprognostic (1.96e-1)" "prognostic favorable (5.73e-6)" "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (2.91e-2)" "unprognostic (2.46e-1)" 52.0 67.1 45.5 38.5 50.0 60.3 49.9 47.8 61.3 44.1 46.5 57.2 52.3 50.7 23.5 50.2 44.8 35.0 91.9 54.9 48.8 68.5 49.2 42.0 40.3 50.5 45.7 49.3 48.3 45.5 47.9 28.3 52.3 43.8 34.6 24.4 51.7 39.9 100.5 51.7 54.7 34.5 43.9 51.8 52.2 32.1 49.1 35.2 48.0 82.9 34.9 44.3 43.2 47.2 94.9 90.0 47.3 65.9 74.4 59.4 62.0 47.3 64.1 80.5 84.3 76.0 66.5 121.4 80.2 74.7 68.2 67.2 72.6 69.2 30.0 38.9 101.7 43.0 118.9 59.0 85.5 61.6 87.5 76.1 48.0 64.4 69.4 50.4 65.3 50.3 24.7 60.4 64.7 138.5 72.0 76.0 21.6 84.2 118.0 62.7 43.3 105.8 94.4 61.1 59.5 42.8 30.2 96.3 48.0 20.8 39.6 51.9 56.0 49.9 34.1 76.8 112.5 89.0 22.6 152.1 81.8 75.8 57.6 178.1 159.3 165.8 71.8 163.9 68.0 68.5 73.2 71.2 163.1 78.9 57.9 63.7 57.8 86.5 169.6 101.3 107.5 140.1 45.5 50.0 47.8 61.3 54.9 48.8 50.5 45.7 52.3 43.9 49.1 47.2 44.4 35.3 33.8 5.5 49.2 80.9 67.5 103.9 37.5 34.9 48.4 57.9 55.1 50.1 55.0 51.5 29.2 99.8 48.2 145.0 207.4 93.4 132.0 42.2 39.4 44.6 62.3 41.4 5.6 90.5 98.7 48.2 47.9 39.8 93.8 43.6 43.2 35.4 131.0 18.5 6.4 107.0 79.3 98.0 77.0 284.2 53.4 75.6 67.6 3.7 116.4 50.8 64.9 3.0 5.0 73.5 133.8 58.6 49.7 35.6 222.4 253.1 50.7 49.3 52.6 47.4 68.2 15.9 18.3 50.3 77.4 110.8 55.2 103.0 112.7 64.2 IGSF5 JAM4 ENSG00000183067 "Immunoglobulin superfamily member 5" Q9NSI5 21 39745407-39802096 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 114.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 5.8" HPA057282 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Focal adhesion sites" "HPA057282: AB_2683395" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (7.06e-2)" "unprognostic (9.73e-5)" "unprognostic (1.56e-2)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (2.09e-1)" "unprognostic (8.35e-2)" "unprognostic (9.61e-2)" "unprognostic (4.01e-1)" "unprognostic (4.18e-1)" "unprognostic (3.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.07e-2)" 0.3 1.2 2.0 0.2 2.8 0.4 0.9 0.6 1.9 0.7 2.4 0.4 0.3 0.7 1.9 0.2 0.7 0.4 3.3 1.5 2.6 0.4 0.4 0.3 0.4 1.5 1.6 1.0 1.5 0.2 0.6 2.5 1.3 1.4 0.7 1.2 0.5 0.4 0.2 0.5 0.3 0.4 0.7 0.4 0.5 1.1 3.6 0.6 0.6 0.1 0.4 0.4 0.1 1.4 0.7 0.4 2.4 0.6 2.3 1.8 0.6 0.4 0.6 0.6 1.0 0.4 0.7 0.8 0.6 0.9 0.9 0.6 0.8 1.6 1.3 1.3 1.1 0.7 1.9 0.3 1.4 1.0 0.3 1.7 2.9 1.5 1.7 1.2 0.3 0.3 1.4 0.5 0.9 0.9 0.2 0.3 1.3 0.6 0.4 0.4 1.1 0.4 1.0 1.0 1.1 0.3 0.6 1.6 1.0 1.0 5.8 0.6 0.2 1.0 1.2 0.5 1.0 0.5 0.4 0.5 0.6 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.0 2.8 0.6 1.9 1.5 2.6 1.5 1.6 1.3 0.7 3.6 1.4 0.0 0.0 0.0 8.5 0.0 0.0 0.2 0.0 0.0 1.2 1.0 0.8 9.7 0.0 0.1 1.8 0.0 1.6 0.0 0.6 5.9 0.6 12.8 0.0 0.4 0.2 0.0 0.0 2.9 0.2 1.7 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 4.1 0.4 0.0 0.0 0.0 4.8 0.3 0.1 0.0 0.0 0.0 1.0 0.0 5.0 1.0 0.2 0.2 0.4 0.0 1.4 0.0 6.8 0.1 0.2 0.0 0.0 0.2 0.5 0.2 0.0 0.0 114.1 0.1 1.1 0.4 2.0 IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34650702-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 57.8;Late spermatids: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 36.8;HSkMC: 38.2" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652" Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229" "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" 26.6 14.8 20.0 15.5 22.9 13.7 30.2 23.9 23.8 44.6 17.2 58.0 21.7 32.9 12.2 16.3 36.8 19.5 66.4 20.6 20.4 21.9 50.7 22.6 32.0 21.4 21.5 38.0 12.9 29.2 21.8 10.3 20.4 30.3 11.4 18.7 26.1 15.7 30.0 61.3 37.9 19.6 20.8 33.3 26.0 18.3 21.6 16.9 48.0 28.5 21.1 32.2 34.1 22.9 2.5 5.5 11.7 11.7 16.5 28.9 5.5 13.8 19.1 8.8 11.9 2.0 4.6 2.6 3.7 36.8 3.3 5.0 3.4 5.0 3.5 23.8 9.2 7.9 23.4 1.0 8.4 2.7 4.3 38.2 6.1 4.9 1.7 11.9 5.6 16.4 3.3 5.4 11.3 1.6 3.6 18.6 2.5 2.0 3.7 5.6 2.3 2.7 2.9 2.5 3.4 12.3 1.7 3.7 5.3 6.1 10.1 10.2 5.2 4.1 10.0 3.2 0.0 3.7 2.6 1.0 10.9 3.1 20.1 2.1 1.0 0.0 1.4 1.4 2.1 0.8 2.7 2.2 1.3 1.0 2.5 1.8 0.3 1.0 0.3 0.5 1.7 1.7 20.0 22.9 23.9 23.8 20.6 20.4 21.4 21.5 20.4 20.8 21.6 22.9 15.8 3.2 14.3 26.8 2.6 17.5 5.8 3.6 6.2 19.6 6.4 25.1 37.9 1.5 3.6 3.7 14.6 11.3 5.1 3.7 0.0 1.9 18.3 0.7 4.4 15.2 9.1 0.8 4.3 0.7 4.1 42.7 3.1 1.3 0.0 57.8 17.5 32.1 4.6 23.5 9.0 5.0 0.0 3.5 19.6 97.2 11.1 3.6 32.0 4.7 2.6 15.2 6.2 5.0 7.3 0.3 4.3 5.7 2.4 2.9 7.0 2.4 1.4 9.0 0.0 32.9 8.9 4.6 21.6 1.4 14.1 12.4 6.0 12.2 5.2 1.7 ILVBL "209L8, AHAS, FLJ39061, HACL1L, ILV2H, MGC1269, MGC19535" ENSG00000105135 "IlvB acetolactate synthase like" A1L0T0 19 15114984-15125786 "Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 148.2;Syncytiotrophoblasts: 253.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067682 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus, Vesicles" "HPA067682: AB_2685885" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.04e-2)" "unprognostic (2.53e-1)" "unprognostic (3.83e-1)" "unprognostic (5.60e-2)" "unprognostic (1.77e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.91e-8)" "unprognostic (4.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (2.40e-1)" 29.7 45.5 22.7 13.9 27.5 15.5 27.5 30.9 25.1 29.7 32.8 46.2 50.1 24.3 14.4 40.9 22.6 25.5 73.7 21.4 25.5 41.6 56.8 19.2 15.5 29.2 25.3 28.3 42.5 65.8 34.4 19.2 26.3 24.2 18.6 13.8 27.7 23.2 18.7 43.4 43.7 13.7 24.8 17.6 41.1 25.5 25.2 10.5 48.0 25.0 10.6 28.5 30.6 32.3 68.8 41.0 34.4 40.7 43.8 29.7 39.6 31.6 42.2 37.2 47.5 65.5 162.1 29.7 61.1 34.2 22.3 50.6 20.9 38.5 10.8 27.5 41.1 43.7 41.3 72.4 70.1 37.2 37.0 44.6 43.9 21.7 28.3 30.4 35.0 29.6 17.9 37.6 29.3 159.0 24.9 29.6 31.9 54.9 58.8 36.0 31.1 46.5 32.3 33.6 28.4 38.3 18.8 81.2 62.1 13.2 37.2 31.2 37.7 55.9 30.7 71.0 45.1 26.1 29.2 15.1 35.9 35.8 43.1 22.7 22.2 5.5 21.1 31.8 24.0 11.9 17.7 22.0 26.3 12.9 22.9 23.6 2.5 23.7 30.3 19.1 20.2 23.3 22.7 27.5 30.9 25.1 21.4 25.5 29.2 25.3 26.3 24.8 25.2 32.3 28.0 25.6 11.7 18.3 12.7 12.7 26.8 53.8 22.2 95.3 18.0 14.9 36.1 62.9 43.0 25.8 27.1 84.2 15.8 67.8 19.6 48.4 6.2 9.9 13.4 23.2 44.4 12.6 4.9 50.6 148.2 21.4 40.2 13.0 11.4 29.0 26.7 59.3 43.2 18.5 8.3 60.6 28.5 12.1 9.5 6.5 25.7 15.8 83.6 5.6 6.8 48.0 7.2 9.0 15.7 32.3 68.4 19.9 17.2 18.6 123.0 50.4 26.1 36.8 19.7 14.7 21.2 20.3 20.8 25.0 16.2 253.4 11.8 48.2 73.2 23.4 IMMT "HMP, Mic60, MICOS60, MINOS2, P87, P89" ENSG00000132305 "Inner membrane mitochondrial protein" Q16891 2 86143932-86195472 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 288.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 223.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022439, HPA036164, HPA036165" Supported Enhanced Mitochondria NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB022439: , HPA036164: AB_2674979, HPA036165: AB_2674980" "unprognostic (3.83e-3)" "unprognostic (1.56e-1)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.40e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (5.66e-2)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (7.35e-2)" "unprognostic (2.21e-1)" "prognostic favorable (3.51e-6)" "unprognostic (2.06e-3)" "unprognostic (6.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" 41.3 82.4 30.3 34.9 31.8 40.3 36.5 33.1 39.0 30.2 41.9 57.4 57.4 35.0 27.6 43.4 30.9 27.1 174.8 31.9 34.5 80.9 65.0 32.5 44.3 35.3 34.2 28.1 48.5 90.2 36.0 36.7 35.1 29.4 58.1 42.4 37.9 35.1 200.9 38.0 46.6 38.9 29.8 44.8 56.0 49.2 32.6 52.3 35.5 288.9 47.1 41.5 33.8 32.8 115.6 111.2 99.2 45.6 93.7 88.3 101.5 80.5 85.6 108.0 98.7 160.7 89.1 175.7 78.9 87.7 87.7 83.4 128.9 118.4 131.8 71.4 105.9 139.0 65.6 192.0 95.7 135.9 91.1 100.6 84.0 101.7 119.5 67.2 124.7 99.7 138.4 96.7 105.1 99.0 135.6 140.8 117.8 175.1 88.2 89.9 211.2 158.7 122.5 128.3 119.3 89.0 82.9 124.0 126.3 77.4 70.7 94.6 93.6 76.0 83.6 112.0 101.8 76.6 104.1 119.9 86.9 158.8 94.4 12.1 29.2 12.2 23.5 34.0 20.7 15.9 20.6 19.3 32.9 13.7 18.3 22.3 3.8 20.8 33.2 17.2 23.2 25.4 30.3 31.8 33.1 39.0 31.9 34.5 35.3 34.2 35.1 29.8 32.6 32.8 29.3 54.5 49.2 31.3 42.1 23.3 34.9 51.6 30.1 40.9 21.6 19.7 223.0 24.3 57.3 40.5 33.3 94.9 49.6 57.9 133.1 59.9 152.4 26.5 34.0 38.3 56.0 76.1 41.6 52.8 73.9 36.3 39.8 26.8 48.0 55.6 35.7 64.2 70.9 23.5 46.5 46.2 38.7 49.4 28.3 158.9 27.7 48.9 17.8 26.2 80.6 30.2 52.5 29.1 44.1 43.3 36.3 36.9 56.4 28.6 59.8 92.6 41.8 42.5 6.6 39.7 58.2 100.7 54.6 41.1 24.9 98.5 45.6 118.6 68.0 33.6 INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134697 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "parathyroid gland: 123.2;thyroid gland: 204.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 35.0;Distal enterocytes: 24.0;Inhibitory neurons: 19.5;Muller glia cells: 25.2;Proximal enterocytes: 62.3" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 19.6;SK-BR-3: 41.1;T-47d: 25.7;U-698: 18.1" "Region enhanced" "Detected in all" "olfactory bulb: 131.0" "Low region specificity" "Detected in all" HPA034539 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoli fibrillar center" "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favorable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favorable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" 0.8 2.1 3.2 0.8 4.8 0.1 8.9 17.3 13.2 4.0 2.4 10.4 16.3 3.0 0.6 2.4 2.3 1.2 27.8 11.5 15.2 32.1 0.4 2.3 0.5 6.0 4.0 1.2 15.7 123.2 10.1 0.1 5.2 9.2 3.7 5.3 33.1 12.1 2.8 4.4 26.2 1.5 1.4 0.3 13.6 4.4 8.3 0.2 204.2 2.6 0.4 2.7 2.4 5.7 2.1 2.0 1.2 2.3 0.3 0.2 1.1 0.8 0.8 4.1 4.0 1.2 1.3 0.1 1.0 0.4 0.4 2.4 2.5 1.2 1.7 0.0 6.5 0.0 9.7 0.4 0.8 19.6 0.2 0.2 1.3 3.4 0.4 2.7 0.3 0.1 1.8 2.8 0.1 6.4 0.1 0.1 2.3 2.8 0.4 0.0 0.4 4.5 1.7 2.5 9.9 7.5 1.6 41.1 0.5 1.1 25.7 1.6 0.0 0.2 7.3 0.8 0.5 0.1 3.5 18.1 0.7 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 4.8 17.3 13.2 11.5 15.2 6.0 4.0 5.2 1.4 8.3 5.7 0.7 0.0 4.1 3.3 0.0 0.9 2.3 0.3 1.2 9.5 15.8 7.5 6.1 0.0 1.1 35.0 0.0 0.0 0.2 24.0 11.7 1.4 0.4 1.9 0.4 0.5 0.0 0.0 5.5 2.2 0.2 0.6 4.6 2.7 0.0 0.8 0.0 0.0 0.1 5.0 19.5 6.4 0.0 0.0 1.9 0.6 0.0 0.3 0.0 1.0 0.6 25.2 0.0 2.0 1.0 0.8 12.3 0.0 0.1 2.5 62.3 0.5 0.5 3.1 0.0 0.5 1.3 2.4 1.2 1.1 1.3 0.1 0.4 0.4 8.8 1.6 INSYN1 "C15orf59, LOC388135, MGC131524" ENSG00000205363 "Inhibitory synaptic factor 1" Q2T9L4 15 73735458-73753351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.6;heart muscle: 48.5" "Cell type enriched" "Detected in single" 24 "Cardiomyocytes: 14.7" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 8.7;fHDF/TERT166: 5.8;HEK 293: 3.9;NTERA-2: 3.4;SK-BR-3: 4.7;U-2 OS: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041563 Approved Approved Nucleoplasm,Cytosol No NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA041563: AB_10794670" "unprognostic (2.28e-2)" "unprognostic (2.47e-2)" "unprognostic (4.85e-2)" "unprognostic (2.36e-1)" "unprognostic (1.71e-1)" "unprognostic (9.36e-2)" "unprognostic (3.37e-2)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (8.36e-2)" "unprognostic (2.67e-4)" "unprognostic (2.67e-2)" "prognostic favorable (5.38e-9)" "unprognostic (4.98e-2)" "unprognostic (5.19e-2)" "unprognostic (2.46e-4)" "unprognostic (1.20e-3)" 3.5 2.6 32.6 0.9 30.1 0.1 1.9 27.2 42.8 7.9 1.6 6.6 0.8 4.2 3.4 12.0 7.8 1.9 48.5 38.9 28.8 15.5 0.4 2.7 0.2 26.9 56.6 13.5 1.4 2.9 5.2 0.5 27.7 10.6 0.6 3.9 3.3 11.0 4.6 13.3 2.4 3.2 22.8 0.7 3.7 4.5 46.3 0.2 2.1 2.6 0.9 6.4 16.9 34.7 0.0 0.0 1.8 1.2 8.7 0.1 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.8 1.0 2.1 1.9 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.5 0.4 4.7 0.4 1.3 2.0 0.1 0.0 1.3 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.6 30.1 27.2 42.8 38.9 28.8 26.9 56.6 27.7 22.8 46.3 34.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IPO13 "IMP13, KIAA0724, RANBP13" ENSG00000117408 "Importin 13" O94829 1 43946950-43968022 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 122.1;skeletal muscle: 128.3" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5;Late spermatids: 91.1;Oligodendrocytes: 79.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070425 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" "CAB070425: AB_11157631" "unprognostic (7.15e-3)" "unprognostic (1.85e-1)" "unprognostic (1.56e-1)" "unprognostic (2.04e-1)" "unprognostic (4.15e-2)" "unprognostic (7.11e-2)" "prognostic unfavorable (8.26e-7)" "unprognostic (1.21e-1)" "unprognostic (9.61e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.21e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-3)" "unprognostic (6.42e-2)" "unprognostic (4.22e-2)" "unprognostic (8.13e-2)" "unprognostic (5.93e-3)" 11.9 22.6 67.6 9.8 94.1 9.6 11.7 80.4 82.5 15.8 49.3 20.8 9.2 18.9 13.8 20.0 14.1 9.3 44.7 66.5 69.4 26.8 18.9 12.2 9.8 84.6 85.8 13.4 13.7 27.5 26.4 10.2 79.2 18.9 10.1 23.9 15.8 16.1 128.3 14.9 14.0 15.7 70.2 15.4 16.8 48.5 95.9 14.2 21.2 74.1 10.4 18.0 15.2 122.1 22.2 17.7 17.5 27.8 46.5 24.0 14.6 20.8 19.3 30.5 23.2 13.6 11.0 23.1 21.0 27.3 19.3 24.3 31.7 36.7 20.1 23.6 27.1 24.1 34.0 18.9 32.7 16.2 21.6 24.6 36.7 39.6 24.6 22.8 20.5 17.7 24.6 20.7 24.6 15.4 16.5 21.3 16.1 18.9 29.4 22.6 22.0 24.2 22.4 21.2 27.8 12.9 19.5 32.5 27.5 22.7 20.4 22.3 16.8 30.3 18.1 26.7 23.9 23.0 30.4 11.0 19.3 34.6 26.9 0.0 1.4 1.2 2.0 1.6 1.7 1.1 1.3 2.0 2.3 0.8 1.1 1.5 0.5 1.9 1.6 2.3 1.7 1.0 67.6 94.1 80.4 82.5 66.5 69.4 84.6 85.8 79.2 70.2 95.9 122.1 4.2 0.0 2.0 13.1 7.4 3.3 3.2 9.1 2.8 18.9 5.6 4.1 23.4 12.8 6.3 11.0 8.4 6.4 5.1 8.6 1.9 7.3 53.5 8.0 5.6 5.8 3.0 4.8 9.8 4.2 3.7 5.2 6.1 6.0 0.0 12.6 3.6 11.5 16.3 28.6 8.8 5.3 12.2 8.3 3.3 91.1 8.4 5.8 8.8 1.9 7.1 11.6 4.1 5.5 79.2 5.9 1.1 15.8 6.2 4.3 9.1 18.2 8.6 8.7 0.0 6.4 10.4 32.4 12.3 7.1 4.3 4.1 3.6 8.4 7.3 3.8 ISCU "hnifU, ISU2, NIFUN" ENSG00000136003 "Iron-sulfur cluster assembly enzyme" Q9H1K1 12 108562582-108569368 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1430.2;Late spermatids: 969.5;Proximal tubular cells: 1315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006329, HPA038602, HPA057592" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB006329: AB_425907, HPA038602: AB_2676109, HPA057592: AB_2683478" "unprognostic (1.72e-1)" "prognostic favorable (4.90e-7)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (2.43e-1)" "unprognostic (3.15e-2)" "unprognostic (1.33e-1)" "unprognostic (6.69e-3)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-3)" "unprognostic (2.49e-2)" "prognostic favorable (2.73e-7)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-3)" "prognostic favorable (6.12e-4)" 174.8 387.6 186.3 89.8 187.5 98.2 166.8 209.9 216.8 174.4 222.2 222.9 88.8 170.2 148.8 91.2 142.5 106.5 507.1 186.2 223.0 341.3 119.9 138.3 138.9 223.4 192.5 169.2 106.2 286.0 228.9 111.1 214.4 150.5 112.0 58.9 123.7 196.1 422.3 111.6 142.7 122.2 187.0 163.9 169.2 123.2 188.0 151.6 184.4 381.5 138.3 179.0 133.4 177.0 47.5 113.8 78.9 47.3 277.4 211.6 191.7 92.8 152.2 69.7 65.7 84.9 66.0 47.4 77.9 128.5 74.6 67.5 76.2 106.8 62.5 147.2 82.0 51.8 60.7 190.6 161.5 124.4 59.0 206.6 234.3 75.4 149.3 176.8 107.7 100.7 98.3 148.8 147.8 102.9 98.1 225.4 76.4 70.9 165.7 64.0 52.5 205.3 204.5 134.6 67.4 62.4 67.5 39.7 108.7 98.3 102.2 99.4 92.3 70.3 59.0 56.8 47.8 175.9 207.8 146.3 109.5 91.8 72.4 478.2 182.1 567.9 224.5 200.5 269.2 564.4 292.6 292.7 128.4 516.7 366.2 305.0 554.2 207.5 239.3 225.2 334.2 400.8 186.3 187.5 209.9 216.8 186.2 223.0 223.4 192.5 214.4 187.0 188.0 177.0 129.8 76.9 158.9 19.9 206.3 98.1 148.6 227.0 98.4 46.2 137.5 212.3 674.1 145.8 148.6 233.6 10.4 453.7 142.2 120.1 1430.2 154.3 433.2 78.1 76.5 140.8 75.0 165.5 52.6 149.8 164.0 165.5 64.2 37.1 116.5 89.1 126.0 112.3 263.0 45.4 53.7 117.6 193.3 140.1 110.2 969.5 202.0 129.9 249.1 23.4 502.4 167.9 163.7 14.6 26.0 141.3 96.3 308.4 299.4 171.8 235.9 1315.1 160.4 45.8 223.5 97.4 158.1 294.5 242.1 92.6 93.1 475.2 153.6 154.2 139.8 177.7 ITGB1BP2 CHORDC3 ENSG00000147166 "Integrin subunit beta 1 binding protein 2" Q9UKP3 X 71301750-71305371 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.4;skeletal muscle: 46.1;tongue: 52.9" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 80.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 9.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA040721 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA040721: AB_10805827" "unprognostic (1.87e-1)" "unprognostic (2.65e-2)" "unprognostic (6.91e-5)" "unprognostic (1.95e-2)" "unprognostic (7.92e-2)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (9.02e-2)" "unprognostic (4.69e-2)" "unprognostic (2.15e-2)" "unprognostic (4.85e-2)" "unprognostic (3.17e-1)" "unprognostic (3.08e-11)" "unprognostic (4.38e-2)" "unprognostic (3.63e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-1)" 0.7 0.6 0.5 1.5 0.6 1.5 0.5 1.0 0.9 2.4 0.5 6.5 1.0 16.6 3.0 4.1 3.3 2.5 89.4 0.6 0.6 0.8 1.4 1.0 0.9 0.6 0.6 1.6 0.5 0.0 0.5 0.3 0.6 6.0 1.8 1.8 1.3 10.3 46.1 0.6 2.1 16.3 0.5 1.1 2.0 1.3 0.6 1.0 0.7 52.9 0.6 5.5 1.5 0.7 0.5 1.4 2.1 1.8 0.1 0.1 0.4 0.7 1.0 0.5 0.5 0.9 1.1 2.1 0.2 1.1 0.5 0.9 1.9 0.6 1.1 0.7 0.9 1.3 1.5 0.4 0.2 0.4 9.3 1.1 0.7 0.2 0.3 0.4 0.8 2.2 1.0 0.5 1.1 0.4 0.8 2.3 3.1 1.4 0.9 1.4 1.6 0.8 1.0 1.3 1.0 0.3 0.5 0.1 0.6 1.4 0.5 0.3 0.0 0.9 1.8 0.1 0.4 1.8 2.8 3.1 0.2 1.6 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.0 0.9 0.6 0.6 0.6 0.6 0.6 0.5 0.6 0.7 0.2 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 1.7 0.3 0.3 80.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.6 0.1 0.2 0.2 0.8 0.0 0.4 0.2 0.0 0.1 2.3 0.0 0.2 0.0 0.4 1.1 0.8 0.2 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.3 0.1 1.0 0.0 0.5 0.2 0.1 8.6 0.0 0.3 0.1 0.5 0.3 1.1 0.0 0.6 2.5 0.5 0.4 0.0 0.3 0.0 0.1 0.6 0.3 0.1 ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.8;Alveolar cells type 2: 202.5;Basal prostatic cells: 153.5;Basal respiratory cells: 125.9;Pancreatic endocrine cells: 195.2;Spermatocytes: 286.0;Urothelial cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 139.2;RPTEC TERT1: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" 0.1 0.0 0.0 1.9 0.0 0.0 20.2 0.0 0.0 2.7 0.0 8.0 8.4 5.4 1.7 14.2 3.4 14.8 0.6 0.0 0.0 68.3 0.1 45.3 0.0 0.0 0.0 0.0 3.3 32.2 1.8 5.5 0.0 5.1 7.4 0.0 3.9 8.9 80.0 2.6 6.3 0.3 0.0 0.0 18.7 0.1 0.0 0.0 4.7 64.5 3.0 44.9 6.5 0.0 14.5 0.2 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 139.2 0.1 0.8 0.1 0.0 28.7 0.0 45.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 31.4 0.0 0.1 0.4 0.1 0.0 0.0 0.0 3.8 4.3 0.0 0.0 0.0 9.0 0.0 0.0 10.9 0.0 269.9 45.7 0.0 0.1 0.1 43.7 0.0 1.6 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 153.8 202.5 0.0 0.0 10.5 153.5 125.9 46.1 0.0 35.5 31.0 38.7 10.0 60.4 71.7 0.0 13.6 0.5 30.3 0.0 57.5 89.4 9.6 0.7 2.6 0.0 0.0 0.3 105.4 7.0 2.6 37.8 24.4 3.8 0.0 1.1 1.0 2.2 0.0 0.2 11.6 24.4 0.3 0.4 48.3 2.8 2.2 1.8 0.0 2.0 1.7 0.0 0.5 0.1 195.2 25.6 1.2 0.0 57.3 10.0 1.9 17.7 0.1 0.0 5.7 3.8 286.0 3.0 42.2 8.5 4.7 2.1 0.0 12.4 129.3 IVD ACAD2 ENSG00000128928 "Isovaleryl-CoA dehydrogenase" P26440 15 40405485-40435947 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Theca cells: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041391, HPA044250" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA041391: AB_2677449, HPA044250: AB_2678875" "unprognostic (9.30e-2)" "unprognostic (3.31e-1)" "unprognostic (1.36e-2)" "unprognostic (4.24e-2)" "unprognostic (7.53e-2)" "unprognostic (1.74e-1)" "prognostic favorable (1.95e-5)" "unprognostic (1.50e-2)" "unprognostic (2.53e-1)" "unprognostic (2.84e-2)" "unprognostic (4.08e-2)" "unprognostic (2.31e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.40e-1)" "unprognostic (3.40e-2)" "unprognostic (1.14e-1)" "unprognostic (5.46e-3)" 25.8 80.5 35.1 14.5 40.8 15.9 45.3 35.6 40.8 29.4 39.5 31.6 24.3 26.4 29.0 16.0 35.0 21.5 61.7 34.0 41.5 59.1 145.4 24.3 19.6 40.2 38.8 43.3 27.4 39.2 58.3 15.3 37.5 42.1 27.2 13.0 31.8 36.8 55.7 8.6 26.8 23.8 37.9 27.9 46.7 25.0 44.5 16.8 119.2 55.4 19.5 31.1 20.8 45.3 20.9 11.9 22.9 38.9 35.9 32.9 1.0 27.6 32.7 39.4 24.0 36.5 16.0 0.8 57.7 43.4 32.6 20.8 45.9 46.6 30.1 36.4 34.0 52.1 36.2 38.9 64.6 22.0 48.5 45.3 18.5 23.5 55.3 46.3 38.8 60.4 2.5 2.4 42.1 27.1 27.3 38.9 17.8 1.3 33.0 41.2 32.6 27.9 45.2 51.6 37.3 21.5 38.2 83.4 18.7 21.5 69.0 117.6 27.6 29.9 20.2 23.6 24.9 54.5 38.5 1.0 30.9 22.8 28.4 17.0 24.8 36.7 33.3 36.1 31.0 27.5 18.5 26.6 58.8 27.6 18.5 26.7 2.3 39.4 73.1 89.2 26.9 24.3 35.1 40.8 35.6 40.8 34.0 41.5 40.2 38.8 37.5 37.9 44.5 45.3 13.1 28.9 54.5 27.4 19.0 2.3 21.0 17.3 13.1 26.0 27.5 22.2 88.0 45.8 29.9 44.1 14.6 20.3 34.0 17.9 95.9 19.7 5.4 21.4 31.0 18.6 19.7 21.3 15.3 14.9 7.3 20.2 29.6 19.9 34.7 46.5 21.4 135.0 28.1 16.8 16.6 24.4 14.2 18.3 6.2 7.4 20.5 18.6 5.4 21.5 28.8 26.0 26.8 25.1 21.4 14.8 9.4 24.8 10.0 16.6 22.0 97.3 29.3 19.9 19.7 25.0 18.2 16.1 3.7 17.4 0.6 9.9 18.0 105.7 35.4 11.9 JPH2 JP-2 ENSG00000149596 "Junctophilin 2" Q9BR39 20 44106590-44187188 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.2;skeletal muscle: 120.4" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 64.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 15.3;EFO-21: 15.0;fHDF/TERT166: 19.1;HeLa: 12.6;SiHa: 12.9" "Low region specificity" "Detected in some" HPA052646 Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA052646: AB_2681899" "unprognostic (1.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.61e-4)" "unprognostic (4.71e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.45e-3)" "unprognostic (6.87e-2)" "unprognostic (9.16e-2)" "unprognostic (2.57e-2)" "unprognostic (9.73e-2)" "unprognostic (4.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-2)" 6.0 1.9 0.5 4.5 0.6 0.1 5.7 0.4 0.7 15.1 0.7 63.3 2.1 51.6 2.9 11.9 30.0 3.5 85.2 0.4 0.5 1.4 0.3 5.2 0.2 1.1 1.1 3.9 0.3 0.1 1.2 3.8 0.8 23.8 4.5 0.2 5.8 22.1 120.4 3.8 11.8 27.5 0.9 1.3 16.0 0.8 0.6 0.1 1.5 48.3 0.1 40.5 10.6 0.7 7.5 0.8 0.4 0.0 0.3 0.4 1.5 2.2 4.1 5.4 2.3 15.3 5.9 0.0 15.0 19.1 6.1 10.5 0.0 0.5 2.1 0.0 0.0 0.0 12.6 0.1 0.1 0.3 0.0 0.7 1.1 2.7 3.7 3.3 0.0 0.0 0.0 0.0 7.3 4.3 0.0 0.2 0.3 0.0 0.9 1.7 3.4 0.0 0.4 0.1 0.0 0.1 12.9 3.1 0.1 8.6 10.8 0.1 0.3 2.4 2.7 0.5 4.7 0.1 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.7 0.4 0.5 1.1 1.1 0.8 0.9 0.6 0.7 0.2 0.0 0.0 0.3 0.0 6.6 0.5 0.9 0.0 0.0 0.4 5.1 64.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.8 0.0 0.5 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.2 0.0 6.6 15.9 12.8 0.0 1.5 0.0 2.0 0.5 0.1 0.0 0.2 0.1 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KBTBD12 "FLJ46299, KLHDC6" ENSG00000187715 "Kelch repeat and BTB domain containing 12" Q3ZCT8 3 127915232-127987671 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 13.8;skeletal muscle: 58.8;tongue: 25.8" "Cell type enhanced" "Detected in many" "Astrocytes: 43.4;Early spermatids: 32.0;Excitatory neurons: 29.9;Microglial cells: 74.0" "Cancer enhanced" "Detected in some" "cervical cancer: 1.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 5.1" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.60e-2)" "unprognostic (2.19e-2)" "unprognostic (3.37e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (3.01e-1)" "unprognostic (3.35e-2)" "unprognostic (4.69e-3)" "unprognostic (3.62e-1)" "unprognostic (2.08e-1)" "unprognostic (2.28e-2)" "unprognostic (1.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.41e-2)" "unprognostic (5.70e-2)" "unprognostic (9.49e-2)" 0.3 0.2 1.3 0.3 1.5 0.2 0.2 1.6 1.6 0.2 2.7 1.8 0.8 0.3 0.1 0.7 0.9 0.7 13.8 1.6 0.6 1.2 0.0 0.2 0.1 0.7 0.7 0.1 4.0 0.0 0.5 0.1 0.7 0.5 1.2 0.7 1.9 0.2 58.8 0.3 0.7 0.7 0.5 0.0 2.0 1.0 0.7 0.0 0.0 25.8 0.0 0.8 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.6 1.6 1.6 0.6 0.7 0.7 0.7 0.5 0.7 1.2 0.0 3.2 3.7 43.4 0.0 0.1 0.1 0.0 0.0 1.0 0.4 0.1 12.1 0.0 1.4 1.8 6.2 0.0 0.1 2.3 1.9 0.1 32.0 1.3 0.0 0.2 2.4 1.7 29.9 9.3 0.0 0.7 7.1 0.8 0.0 0.1 0.0 0.0 0.1 1.7 15.7 5.8 0.0 0.0 1.0 3.2 0.0 0.3 0.0 74.0 0.0 1.6 0.0 3.0 2.2 5.9 5.8 0.0 0.1 0.0 1.4 0.0 1.2 0.9 0.0 1.6 1.0 6.2 5.7 0.0 0.3 0.0 0.0 0.1 1.9 0.1 KBTBD13 "hCG_1645727, NEM6" ENSG00000234438 "Kelch repeat and BTB domain containing 13" C9JR72 15 65076746-65079948 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 30.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062737 Uncertain NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" "HPA062737: AB_2684856" "unprognostic (1.18e-1)" "unprognostic (7.88e-2)" "unprognostic (6.07e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.2 0.5 0.1 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNE1B ENSG00000276289 "Potassium voltage-gated channel subfamily E regulatory subunit 1B" A0A087WTH5 21 7816675-7829926 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.1;fallopian tube: 5.7;heart muscle: 6.2" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 1.2;Kupffer cells: 1.2;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.0;eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 1.8;SuSa: 1.1" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (5.41e-4)" "unprognostic (8.78e-2)" "unprognostic (7.14e-3)" "unprognostic (1.35e-1)" "unprognostic (3.34e-2)" "unprognostic (1.78e-2)" "unprognostic (3.08e-1)" "unprognostic (7.47e-2)" "unprognostic (3.24e-1)" "unprognostic (1.73e-3)" "unprognostic (6.59e-2)" "unprognostic (1.49e-1)" 0.2 0.0 0.3 0.0 0.4 0.1 0.9 0.4 0.9 0.2 7.1 0.1 0.0 0.1 0.1 0.1 5.7 0.0 6.2 1.0 0.2 2.6 0.9 1.0 0.0 1.4 1.7 0.0 0.0 0.7 0.3 0.2 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.8 1.1 0.6 0.1 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.4 0.4 0.9 1.0 0.2 1.4 1.7 0.8 1.1 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNIP2 KCHIP2 ENSG00000120049 "Potassium voltage-gated channel interacting protein 2" Q9NS61 10 101825974-101843920 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4;brain: 139.6;heart muscle: 307.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.3;Cardiomyocytes: 135.7;Cone photoreceptor cells: 25.0;Excitatory neurons: 23.3;Horizontal cells: 48.8;Inhibitory neurons: 41.9" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 12.7" "Group enriched" "Detected in all" 4 "amygdala: 96.8;basal ganglia: 234.9;cerebral cortex: 106.9;hippocampal formation: 142.6;olfactory bulb: 144.0" "Low region specificity" "Detected in all" HPA066717 Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA066717: " "unprognostic (5.92e-2)" "unprognostic (2.16e-1)" "unprognostic (3.48e-3)" "unprognostic (5.77e-4)" "unprognostic (1.34e-1)" "unprognostic (1.31e-3)" "unprognostic (8.80e-2)" "unprognostic (9.11e-3)" "unprognostic (1.14e-1)" "unprognostic (5.34e-2)" "unprognostic (3.18e-2)" "unprognostic (7.20e-2)" "unprognostic (1.49e-9)" "unprognostic (9.85e-2)" "unprognostic (1.81e-1)" "unprognostic (3.27e-1)" "unprognostic (8.37e-4)" 227.4 6.8 74.5 3.5 139.6 0.9 67.1 48.8 84.5 7.4 40.5 5.0 1.8 4.1 4.1 2.5 4.9 3.1 307.5 98.8 50.6 2.8 2.3 2.5 8.1 47.5 51.6 11.5 2.4 1.7 19.7 2.9 48.1 5.2 4.7 52.6 9.9 3.5 8.0 5.9 5.3 2.6 50.3 5.7 2.7 8.5 57.1 2.3 3.5 5.4 8.3 4.8 4.4 60.8 1.7 2.6 2.5 3.2 1.0 1.1 0.6 1.2 1.0 0.6 0.9 3.6 3.4 1.6 0.9 0.8 0.7 1.7 0.9 0.4 0.6 2.4 2.0 21.3 3.0 1.9 0.9 1.4 12.7 2.6 1.7 1.0 1.4 3.7 1.0 4.7 6.3 1.8 1.0 1.2 0.8 4.0 0.8 0.7 0.6 1.0 0.2 1.4 1.0 1.1 7.4 1.2 0.8 0.6 2.4 1.5 2.2 0.9 2.3 1.3 2.0 0.6 1.2 1.7 1.9 1.7 1.4 5.3 0.2 0.0 0.0 0.7 0.0 0.5 0.1 0.9 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 74.5 139.6 48.8 84.5 98.8 50.6 47.5 51.6 48.1 50.3 57.1 60.8 0.4 0.0 0.0 8.5 2.3 0.4 0.1 0.3 0.0 54.3 0.3 0.5 135.7 0.0 0.1 1.8 25.0 0.2 0.0 0.8 0.0 0.2 6.6 0.0 0.2 1.6 0.0 0.0 23.3 0.0 0.2 5.8 0.0 0.0 0.0 0.8 0.4 0.1 2.2 48.8 41.9 0.4 0.0 0.6 0.8 5.2 1.8 0.3 0.0 1.0 0.5 8.3 0.0 5.5 3.7 0.3 0.2 0.7 0.3 0.1 0.5 0.1 0.2 4.7 0.0 0.1 1.3 2.5 5.5 0.5 0.0 0.3 0.1 0.5 0.3 0.1 KCNJ11 "BIR, Kir6.2" ENSG00000187486 "Potassium inwardly rectifying channel subfamily J member 11" Q14654 11 17385248-17389331 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 134.7;tongue: 40.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.1;Collecting duct cells: 5.5;Enteroendocrine cells: 4.2;Excitatory neurons: 5.5;Inhibitory neurons: 5.9;Oligodendrocyte precursor cells: 4.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 6.6;HEK 293: 12.3;MCF7: 10.0;SCLC-21H: 8.5;U-266/84: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048891 Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA048891: AB_2680547" "unprognostic (1.95e-2)" "unprognostic (6.18e-3)" "unprognostic (7.79e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (4.81e-5)" "unprognostic (1.83e-3)" "unprognostic (5.45e-2)" "unprognostic (8.09e-3)" "unprognostic (3.72e-3)" "unprognostic (9.23e-3)" "prognostic favorable (1.56e-4)" "unprognostic (4.05e-2)" "unprognostic (2.10e-2)" "unprognostic (1.67e-1)" "unprognostic (4.75e-2)" 2.7 0.6 5.1 0.4 8.3 0.2 3.0 12.4 11.9 0.6 0.0 1.1 1.0 0.9 1.6 1.5 0.7 0.5 13.8 5.3 4.2 4.7 1.5 2.5 0.8 8.0 3.4 0.3 11.3 5.0 7.4 0.1 8.2 2.2 0.4 1.3 2.2 2.4 134.7 1.5 1.3 0.1 2.6 1.6 13.1 0.6 6.4 0.3 5.1 40.7 0.5 0.9 0.4 5.9 1.5 2.1 0.2 4.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 2.0 0.2 6.6 0.2 0.0 0.3 0.3 4.1 0.1 0.2 1.6 12.3 3.4 0.9 0.5 0.1 0.5 0.3 0.1 0.2 0.0 0.1 0.1 0.0 5.6 3.5 3.6 0.0 10.0 0.7 0.1 1.1 4.0 0.3 1.3 1.6 2.0 0.3 0.9 8.5 0.7 0.0 3.4 0.0 0.0 4.2 0.2 0.0 0.0 1.1 0.0 0.0 0.2 6.5 0.8 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.1 8.3 12.4 11.9 5.3 4.2 8.0 3.4 8.2 2.6 6.4 5.9 1.5 0.0 2.7 3.3 0.1 0.0 0.1 0.0 0.0 2.1 2.6 0.9 14.1 0.0 0.6 5.5 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.3 0.3 0.3 4.2 0.0 5.5 0.4 0.0 0.9 0.0 0.6 0.0 0.2 0.4 1.3 0.1 0.0 5.9 0.9 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 4.0 0.8 0.1 0.0 0.0 0.0 0.8 0.1 0.2 0.0 0.7 0.0 1.3 0.2 0.2 0.3 1.0 0.0 0.0 0.0 0.1 0.4 0.2 KCNJ4 "HIR, hIRK2, HRK1, IRK3, Kir2.3" ENSG00000168135 "Potassium inwardly rectifying channel subfamily J member 4" P48050 22 38426327-38455199 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 28.9;heart muscle: 33.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.3;Excitatory neurons: 14.3;Horizontal cells: 10.1;Inhibitory neurons: 11.1;Microglial cells: 3.7;Muller glia cells: 6.2" "Cancer enhanced" "Detected in some" "glioma: 2.1;liver cancer: 1.8" "Group enriched" "Detected in many" 5 "amygdala: 10.5;basal ganglia: 18.9;cerebral cortex: 28.9;hippocampal formation: 21.9;white matter: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 11.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 14 "amygdala: 5.9;basal ganglia: 13.7;cerebral cortex: 14.7;hippocampal formation: 12.3;olfactory bulb: 15.9" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.76e-2)" "unprognostic (2.60e-3)" "unprognostic (2.21e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (9.68e-3)" "unprognostic (3.12e-1)" "unprognostic (8.96e-2)" "unprognostic (2.07e-1)" "unprognostic (3.15e-3)" "unprognostic (1.28e-3)" "unprognostic (1.05e-1)" "unprognostic (5.41e-2)" 0.1 0.2 10.5 0.0 18.9 0.0 0.0 0.0 28.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 0.6 33.3 21.9 3.5 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.4 0.8 0.0 0.3 0.1 0.0 1.7 0.0 0.1 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 18.9 0.0 28.9 21.9 3.5 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 11.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 3.7 0.0 6.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 KCNN2 "hSK2, KCa2.2" ENSG00000080709 "Potassium calcium-activated channel subfamily N member 2" Q9H2S1 5 114055926-114496500 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 27.8;brain: 20.8;liver: 31.3" "Cell type enhanced" "Detected in some" "Astrocytes: 36.2;Excitatory neurons: 149.9;Inhibitory neurons: 97.0;Oligodendrocyte precursor cells: 63.3" "Group enriched" "Detected in some" 7 "glioma: 3.5;melanoma: 3.2;prostate cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 17.5;NTERA-2: 6.4;SK-MEL-30: 12.9;THP-1: 21.8;U-937: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038221 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA038221: AB_10673044" "unprognostic (9.22e-3)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (4.61e-1)" "unprognostic (3.16e-1)" "unprognostic (4.25e-1)" 0.4 27.8 7.8 0.2 10.8 0.0 0.5 11.3 14.0 2.0 2.2 1.4 0.3 2.9 0.3 0.2 0.4 0.4 6.8 20.8 7.5 3.9 31.3 2.3 0.4 11.1 4.7 0.7 4.5 0.4 7.6 0.0 6.7 9.6 0.7 2.5 0.5 4.3 9.5 1.3 0.3 2.0 9.0 0.5 0.7 3.0 8.2 0.2 0.3 6.7 0.2 2.3 1.0 11.1 0.1 0.0 0.0 0.0 0.0 0.0 2.1 17.5 2.7 0.3 0.0 0.0 0.2 0.0 0.5 0.0 2.3 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.2 0.0 0.3 0.0 1.4 6.4 0.0 0.0 0.0 0.0 0.8 0.2 0.1 2.1 0.0 0.0 0.2 12.9 0.4 0.3 21.8 0.3 0.0 0.5 1.8 0.0 0.1 0.0 0.1 2.0 7.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 10.8 11.3 14.0 20.8 7.5 11.1 4.7 6.7 9.0 8.2 11.1 1.4 0.0 1.1 36.2 0.0 0.3 0.3 0.0 0.0 7.9 0.6 1.3 15.1 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.6 0.6 0.5 0.0 8.2 0.0 0.0 149.9 0.9 0.0 0.8 0.0 1.3 0.0 0.8 5.0 18.3 0.0 0.0 97.0 1.0 0.0 1.0 0.3 0.5 0.0 0.1 21.4 6.5 0.0 0.4 0.0 63.3 9.2 1.0 0.1 0.0 1.2 4.7 0.0 0.7 0.0 7.8 0.0 0.1 0.3 0.3 6.5 0.3 0.3 0.0 0.0 0.2 0.5 0.6 KCNT1 "KCa4.1, KIAA1422, SLACK, Slo2.2" ENSG00000107147 "Potassium sodium-activated channel subfamily T member 1" Q5JUK3 9 135702185-135795508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 37.1;lymphoid tissue: 15.8;skeletal muscle: 13.4" "Group enriched" "Detected in some" 8 "Excitatory neurons: 60.1;Inhibitory neurons: 55.0;Theca cells: 21.2" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Region enhanced" "Detected in many" "cerebral cortex: 37.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 2.5;RPMI-8226: 1.8;SCLC-21H: 3.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 42.8" HPA059880 Uncertain NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA059880: AB_2684149" "unprognostic (1.50e-3)" "unprognostic (1.72e-2)" "unprognostic (2.07e-3)" "unprognostic (2.98e-13)" "unprognostic (9.26e-2)" "unprognostic (7.73e-2)" "unprognostic (9.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.30e-3)" "unprognostic (9.89e-2)" "unprognostic (6.20e-2)" "unprognostic (4.89e-7)" "unprognostic (9.15e-2)" "unprognostic (2.70e-1)" "unprognostic (2.26e-1)" "unprognostic (1.66e-2)" 0.4 0.1 3.9 0.1 7.9 0.1 0.3 1.9 37.1 0.3 0.0 0.3 0.1 0.1 0.1 0.2 0.6 0.2 1.2 4.2 0.0 0.0 0.1 0.3 0.0 4.5 0.0 5.0 0.1 0.0 8.7 0.3 2.8 0.1 0.0 0.4 0.2 0.0 13.4 0.1 0.2 0.0 0.0 15.8 0.5 0.9 0.0 0.0 0.1 8.2 0.0 0.2 0.2 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 1.8 0.0 0.0 3.7 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.9 1.9 37.1 4.2 0.0 4.5 0.0 2.8 0.0 0.0 12.5 0.0 0.0 0.0 3.6 0.1 0.0 0.3 0.0 0.0 1.3 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 60.1 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 55.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.3 0.0 3.5 2.7 0.0 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.6 0.0 5.1 1.1 0.3 1.0 0.0 0.0 0.0 0.1 21.2 0.0 0.0 KLHDC3 "dJ20C7.3, hPeas, PEAS" ENSG00000124702 "Kelch domain containing 3" Q9BQ90 6 43014103-43021298 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 395.9" "Group enriched" "Detected in all" 5 "Early spermatids: 552.0;Late spermatids: 1588.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030131, HPA030132, HPA030133, HPA030134" Uncertain Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA030131: AB_10599712, HPA030132: AB_10600880, HPA030133: AB_10611532, HPA030134: AB_10601350" "unprognostic (3.85e-2)" "prognostic favorable (9.15e-4)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (9.97e-3)" "unprognostic (2.80e-1)" "unprognostic (2.09e-3)" "unprognostic (1.05e-2)" "unprognostic (5.09e-2)" "unprognostic (1.58e-3)" "prognostic favorable (9.08e-4)" "unprognostic (6.34e-2)" "unprognostic (2.88e-2)" "unprognostic (8.73e-2)" "unprognostic (9.78e-2)" "unprognostic (2.88e-1)" "unprognostic (1.52e-1)" 52.5 64.9 161.4 33.9 170.8 48.6 52.7 144.2 203.3 48.5 139.0 75.0 40.1 44.5 56.3 49.5 53.0 37.4 105.7 178.2 143.8 53.2 73.0 43.2 45.4 150.6 153.9 55.6 51.1 54.6 68.8 59.2 156.5 56.8 40.7 48.2 60.6 47.8 395.9 51.4 48.6 43.3 140.5 54.0 64.8 192.2 158.6 67.1 49.7 203.9 44.8 49.8 46.2 157.1 119.1 36.0 117.1 197.3 79.0 59.4 83.8 52.6 67.7 100.7 109.4 104.5 60.6 117.0 58.7 77.3 37.8 61.6 126.1 67.8 68.5 62.8 171.3 146.0 102.1 109.7 77.4 86.5 99.7 95.8 67.1 77.6 45.2 77.9 98.7 131.1 180.7 80.9 38.4 147.3 142.3 148.9 153.4 297.3 38.0 137.2 86.0 141.4 62.3 67.9 216.1 168.8 55.8 63.2 93.1 75.7 109.8 247.6 58.8 45.7 83.9 50.8 52.9 88.0 118.8 170.9 19.9 122.7 39.4 42.3 83.5 100.3 62.0 78.9 51.9 41.6 50.8 56.0 90.7 39.6 65.6 51.8 40.4 54.7 63.3 49.8 59.5 76.5 161.4 170.8 144.2 203.3 178.2 143.8 150.6 153.9 156.5 140.5 158.6 157.1 21.3 12.8 17.0 10.4 26.7 18.7 32.9 33.5 14.8 31.9 37.8 33.7 40.3 37.1 19.1 18.4 14.6 99.6 32.7 34.8 86.1 61.7 552.0 19.2 19.0 30.4 52.3 59.3 29.1 54.7 115.1 36.2 20.9 18.8 13.4 50.7 32.5 28.4 63.8 32.0 22.0 43.7 34.6 47.0 22.7 1588.3 44.7 31.8 33.8 11.2 54.7 55.4 55.6 11.6 14.8 46.3 44.3 59.0 31.7 44.4 72.6 55.3 16.9 25.9 52.6 30.4 32.2 180.8 35.6 22.8 20.6 107.0 28.3 71.4 53.7 36.7 KLHDC9 KARCA1 ENSG00000162755 "Kelch domain containing 9" Q8NEP7 1 161098361-161100346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 29.0" "Group enriched" "Detected in many" 4 "Early spermatids: 424.7;Late spermatids: 448.2;Spermatocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.5;HEK 293: 1.8;MCF7: 1.4;T-47d: 1.4;U-266/70: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043197 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA043197: AB_2678359" "unprognostic (1.79e-1)" "unprognostic (2.26e-1)" "unprognostic (4.71e-2)" "unprognostic (1.04e-3)" "unprognostic (2.53e-2)" "unprognostic (1.52e-1)" "unprognostic (1.62e-1)" "unprognostic (4.87e-3)" "unprognostic (6.31e-2)" "prognostic favorable (4.20e-6)" "unprognostic (1.81e-3)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.53e-1)" "unprognostic (5.51e-2)" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" 0.4 3.0 1.3 0.1 1.8 0.0 0.7 1.0 2.9 1.1 2.1 1.4 0.2 1.4 0.5 0.5 2.2 0.0 0.9 1.7 2.2 4.7 1.9 0.8 0.0 1.7 1.8 1.0 2.4 1.1 4.6 0.0 1.6 1.7 0.2 0.4 1.0 0.4 0.7 0.3 0.8 0.0 1.2 0.3 1.3 29.0 2.4 0.0 2.4 0.1 0.1 1.0 0.5 0.9 0.1 1.1 0.4 1.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 1.5 1.8 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.5 0.2 0.9 1.0 0.0 0.7 0.2 0.0 1.0 0.4 0.0 0.4 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.8 1.0 2.9 1.7 2.2 1.7 1.8 1.6 1.2 2.4 0.9 2.4 0.0 6.7 8.8 1.5 0.9 11.7 11.5 0.6 13.7 15.3 16.3 9.3 14.3 11.7 29.5 2.1 2.3 0.4 7.6 56.7 10.2 424.7 57.5 2.8 3.4 5.4 0.0 8.9 5.5 3.6 3.2 3.1 10.3 1.3 1.6 3.9 9.5 0.6 3.3 6.8 10.6 16.2 0.6 0.7 448.2 8.1 0.9 7.2 2.8 0.6 35.1 1.0 6.0 1.7 3.9 8.2 8.2 2.1 6.4 2.5 47.8 77.8 20.0 13.1 2.8 4.4 198.1 15.6 2.6 0.9 0.8 1.2 1.7 8.7 8.2 KLHL11 FLJ10572 ENSG00000178502 "Kelch like family member 11" Q9NVR0 17 41848518-41865423 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 108.3;Late spermatids: 41.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 24.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023021, HPA052403, HPA054269" Uncertain Approved "Nucleoplasm,Nuclear membrane" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear membrane" "HPA023021: AB_1852568, HPA052403: , HPA054269: AB_2682432" "unprognostic (9.90e-2)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.82e-1)" "unprognostic (2.07e-1)" "unprognostic (1.84e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-2)" "unprognostic (1.50e-1)" "unprognostic (1.83e-2)" "unprognostic (3.25e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-3)" "unprognostic (4.05e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-2)" "unprognostic (5.07e-2)" 2.0 2.5 7.5 2.0 6.9 9.1 3.6 8.7 8.2 2.2 1.6 2.0 1.7 2.8 4.0 1.8 2.5 1.6 2.0 9.7 7.6 2.6 2.5 2.3 2.8 6.8 6.3 3.9 3.0 4.6 0.8 2.0 7.4 2.9 1.8 7.1 2.2 2.7 4.3 3.2 1.7 1.8 5.1 2.8 2.2 9.7 7.5 2.7 4.5 1.9 2.8 1.6 0.8 7.0 3.3 5.6 3.9 10.3 5.3 2.8 6.8 3.1 2.9 3.3 3.1 5.2 2.5 10.7 3.4 3.8 3.0 9.3 10.1 4.4 6.0 4.1 4.5 3.8 8.2 7.1 4.9 4.7 4.1 3.4 4.0 4.4 8.3 3.4 3.4 5.3 3.4 9.1 4.3 4.2 7.1 4.9 3.4 2.9 1.8 6.1 9.5 7.7 3.7 5.7 9.8 4.8 5.4 24.9 4.2 3.8 10.9 3.8 5.3 5.1 6.9 4.9 6.2 5.6 5.1 7.9 5.4 4.9 4.8 0.2 0.5 0.3 0.5 0.7 0.8 0.6 0.6 0.6 0.5 0.8 0.7 0.6 0.2 0.4 0.4 0.3 0.4 0.4 7.5 6.9 8.7 8.2 9.7 7.6 6.8 6.3 7.4 5.1 7.5 7.0 1.2 0.0 0.5 6.8 4.5 0.5 1.4 0.2 14.8 3.8 0.9 1.8 0.2 0.0 1.5 0.0 4.2 0.4 3.6 0.3 0.0 0.4 108.3 1.6 3.4 1.5 0.0 3.0 16.6 0.2 0.4 3.0 10.7 1.9 0.0 1.1 0.0 0.0 0.3 8.4 18.0 0.7 0.0 0.0 1.0 41.8 0.3 1.5 1.8 4.7 0.9 1.8 1.0 11.1 13.9 0.5 0.1 0.0 5.8 0.9 0.9 0.2 0.0 3.6 6.6 2.2 3.2 5.5 2.1 5.5 0.3 0.4 4.6 0.9 0.6 0.9 KLHL24 "DRE1, FLJ20059" ENSG00000114796 "Kelch like family member 24" Q6TFL4 3 183635610-183684519 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 54.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056337 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 21: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA056337: AB_2683103" "unprognostic (3.68e-1)" "unprognostic (1.37e-3)" "unprognostic (1.62e-1)" "unprognostic (1.53e-3)" "unprognostic (8.56e-3)" "unprognostic (3.85e-1)" "unprognostic (2.09e-1)" "unprognostic (1.02e-2)" "unprognostic (1.32e-1)" "unprognostic (1.20e-1)" "unprognostic (4.80e-3)" "unprognostic (3.31e-1)" "unprognostic (1.39e-3)" "unprognostic (1.08e-1)" "unprognostic (7.85e-2)" "unprognostic (8.40e-2)" "unprognostic (1.02e-2)" 16.5 13.1 8.4 10.5 22.4 41.0 16.1 71.6 33.2 13.7 0.0 14.9 16.0 15.3 10.3 11.5 10.3 13.4 41.3 8.4 9.0 18.5 20.3 18.8 15.8 18.4 17.6 20.0 15.3 41.7 10.4 13.9 21.0 13.9 14.0 16.1 17.8 11.5 48.5 11.2 14.6 11.3 5.1 16.2 15.1 9.0 21.2 17.8 23.3 46.4 14.7 14.0 11.9 28.3 4.4 4.3 9.9 10.5 22.1 12.0 20.6 2.2 16.9 2.7 4.8 2.8 8.0 8.9 30.1 6.1 25.2 6.2 5.7 2.6 4.8 10.1 7.9 5.4 6.9 2.9 18.9 4.7 7.1 24.7 14.0 2.9 9.2 16.7 14.4 13.8 3.5 28.5 3.7 2.1 7.9 6.0 6.4 6.7 6.5 10.0 7.5 28.7 7.8 13.6 17.5 24.5 10.3 32.1 23.5 14.4 11.8 10.4 12.5 3.4 4.4 5.4 2.9 54.1 38.4 37.7 6.0 7.5 2.2 43.1 20.3 25.0 17.3 22.7 14.7 25.7 14.3 15.8 13.8 27.7 20.7 14.8 40.9 16.3 22.5 10.7 20.5 15.3 8.4 22.4 71.6 33.2 8.4 9.0 18.4 17.6 21.0 5.1 21.2 28.3 44.5 112.2 72.3 88.8 73.4 43.6 30.7 21.8 77.4 39.8 33.2 24.8 137.8 27.1 33.4 31.3 70.9 12.1 63.2 32.0 13.7 28.1 16.1 35.5 42.0 39.5 42.3 26.1 99.5 18.9 18.0 44.5 29.6 49.3 26.0 110.1 33.2 47.7 27.1 60.6 104.3 28.5 46.8 51.9 31.4 7.0 30.7 46.5 35.6 68.4 31.3 24.4 41.2 92.0 185.2 18.1 29.3 24.5 48.5 51.9 52.3 27.7 35.8 45.8 32.9 59.7 48.8 27.9 12.4 46.1 43.9 43.8 49.5 45.1 26.0 44.8 KLHL30 FLJ43374 ENSG00000168427 "Kelch like family member 30" Q0D2K2 2 238138668-238152947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 149.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.5;Skeletal myocytes: 9.8;Smooth muscle cells: 3.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;CAPAN-2: 1.6;EFO-21: 1.5;REH: 1.4;RH-30: 4.5;THP-1: 2.3" "Region enriched" "Detected in single" 35 "olfactory bulb: 9.4" "Not detected" "Not detected" HPA062095 Approved "Centriolar satellite" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Centriolar satellite" "HPA062095: AB_2684680" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (2.07e-4)" "unprognostic (6.02e-5)" "unprognostic (1.29e-1)" "unprognostic (1.22e-2)" "unprognostic (1.31e-1)" "unprognostic (4.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "unprognostic (8.17e-4)" "unprognostic (2.75e-2)" "unprognostic (2.30e-1)" "unprognostic (2.06e-1)" 3.8 0.1 0.2 0.1 0.2 0.0 1.4 0.5 0.2 2.2 0.2 1.0 0.2 1.2 0.0 1.0 1.3 0.5 14.3 0.1 0.4 1.0 0.1 0.9 0.0 0.9 0.8 0.4 0.1 0.0 0.1 0.3 0.3 1.0 0.1 0.1 1.0 0.8 149.1 0.8 0.7 0.7 0.1 0.2 0.5 0.1 0.2 0.0 0.6 15.2 0.0 1.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.1 0.1 0.0 0.0 1.4 4.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.2 0.1 0.4 0.9 0.8 0.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 9.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLHL31 "bA345L23.2, BKLHD6, KBTBD1" ENSG00000124743 "Kelch like family member 31" Q9H511 6 53647916-53665756 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 51.3;skeletal muscle: 146.1;tongue: 34.8" "Cell type enriched" "Detected in some" 33 "Cardiomyocytes: 248.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (7.27e-2)" "unprognostic (6.18e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-1)" "unprognostic (7.67e-4)" "unprognostic (2.23e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-1)" "unprognostic (3.98e-2)" "unprognostic (5.50e-2)" "unprognostic (4.24e-1)" "unprognostic (1.09e-4)" "unprognostic (8.73e-2)" "unprognostic (2.88e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" 8.6 0.8 0.2 0.2 0.5 0.0 3.1 0.2 0.3 0.2 0.7 0.2 0.4 0.2 0.8 0.7 0.8 0.2 51.3 0.1 0.3 0.2 0.4 0.2 0.1 0.3 0.2 0.3 0.4 0.0 0.4 0.1 0.3 1.3 0.2 0.4 1.2 0.1 146.1 1.3 0.3 0.0 0.3 0.1 0.3 0.3 0.3 0.1 0.9 34.8 0.2 0.3 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.0 0.3 0.1 0.6 0.4 0.0 0.1 0.0 0.5 0.7 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 0.2 0.0 0.8 0.0 0.2 0.2 1.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.1 0.3 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.0 0.0 0.7 0.0 0.6 0.8 0.7 0.0 0.5 0.9 0.9 248.9 0.0 0.5 0.0 0.0 1.0 0.1 0.6 0.0 0.1 0.4 2.0 0.3 1.7 0.0 3.2 0.2 0.4 0.2 7.5 0.5 3.1 0.0 0.9 0.0 0.2 0.2 0.0 0.2 0.1 2.0 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.5 0.0 0.2 0.0 0.1 0.6 0.0 0.2 0.2 0.1 0.0 3.7 2.2 0.0 0.2 0.0 0.4 0.8 0.3 0.4 0.3 0.4 KLHL32 "BKLHD5, KIAA1900" ENSG00000186231 "Kelch like family member 32" Q96NJ5 6 96924620-97140754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 65.2" "Cell type enhanced" "Detected in many" "Astrocytes: 143.7;Excitatory neurons: 168.8;Inhibitory neurons: 143.9;Oligodendrocyte precursor cells: 197.5;Oligodendrocytes: 724.3" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 2.6" "Cell line enhanced" "Detected in some" "Daudi: 3.3;HDLM-2: 4.5;RPMI-8226: 2.1;SCLC-21H: 1.8;U-266/70: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039150 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039150: AB_2676367" "unprognostic (1.75e-1)" "unprognostic (7.99e-2)" "unprognostic (6.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (5.22e-2)" "unprognostic (5.00e-1)" "unprognostic (3.12e-3)" "unprognostic (5.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.51e-5)" "unprognostic (5.82e-2)" "unprognostic (6.04e-2)" "unprognostic (7.01e-2)" "unprognostic (1.86e-2)" "unprognostic (7.48e-2)" "unprognostic (4.49e-4)" 0.2 0.9 19.6 0.4 40.7 0.1 0.3 24.7 33.3 0.3 1.7 0.6 0.8 0.2 0.4 0.0 6.4 0.3 0.7 21.6 25.9 1.9 0.6 0.7 0.4 31.2 28.2 0.9 1.3 0.7 1.2 0.0 29.9 0.2 0.9 2.5 0.5 0.2 1.2 0.1 1.1 0.1 25.3 0.3 0.5 1.6 29.1 0.7 0.7 0.3 0.4 0.1 0.1 65.2 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 3.3 0.1 0.0 0.0 0.1 0.3 0.1 0.0 4.5 0.7 0.2 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 1.6 0.0 0.0 0.8 0.2 0.2 0.1 0.1 0.1 0.0 2.1 0.0 0.0 1.8 0.6 0.0 0.0 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.3 0.4 1.3 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.9 1.0 1.7 0.6 0.0 0.7 1.9 2.6 0.0 0.4 0.0 0.0 1.2 0.8 19.6 40.7 24.7 33.3 21.6 25.9 31.2 28.2 29.9 25.3 29.1 65.2 0.2 3.2 0.0 143.7 1.1 0.0 0.3 0.1 0.0 2.5 0.4 0.5 2.6 0.0 0.1 5.5 0.0 0.1 0.2 0.3 3.9 0.2 6.9 7.5 0.1 0.0 11.3 0.0 168.8 0.2 0.0 0.3 1.5 0.2 0.0 3.2 0.4 1.3 0.1 18.5 143.9 4.1 0.0 0.0 0.0 3.3 0.0 0.1 0.0 13.1 0.0 1.1 0.0 197.5 724.3 0.0 0.1 0.0 0.5 0.2 0.5 2.4 15.3 1.1 0.0 0.2 0.1 0.8 1.8 0.0 0.0 0.0 0.7 1.1 0.5 0.0 KLHL7 "KLHL6, RP42, SBBI26" ENSG00000122550 "Kelch like family member 7" Q8IXQ5 7 23105758-23177914 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.8" "Cell type enhanced" "Detected in all" "Early spermatids: 560.6;Late spermatids: 242.7;Oligodendrocyte precursor cells: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029491, HPA029492" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029491: AB_10599605, HPA029492: AB_10600881" "unprognostic (1.24e-2)" "unprognostic (4.45e-1)" "unprognostic (1.77e-1)" "unprognostic (4.55e-2)" "unprognostic (1.29e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (3.78e-1)" "unprognostic (6.10e-2)" "unprognostic (6.41e-3)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "prognostic favorable (8.98e-5)" "unprognostic (2.46e-2)" "unprognostic (3.55e-3)" "unprognostic (3.23e-2)" "unprognostic (2.27e-2)" 9.5 18.8 12.8 7.0 13.3 12.4 13.0 16.3 15.9 10.5 12.1 9.2 7.8 11.5 12.2 9.0 9.7 9.7 50.8 12.5 13.1 11.9 10.4 7.7 8.3 12.6 12.7 11.8 7.7 10.8 7.3 8.6 12.3 10.1 7.9 14.9 8.5 8.1 9.1 10.9 6.9 10.5 12.2 8.0 6.3 42.2 13.4 12.4 9.2 9.7 9.1 8.7 9.4 14.7 24.7 20.7 55.7 66.3 26.8 23.2 20.3 21.3 31.5 30.7 35.6 25.3 17.5 24.1 16.8 26.2 50.5 26.2 21.5 15.0 25.8 6.4 15.5 15.9 16.7 32.9 20.0 32.5 12.0 20.7 19.1 35.2 28.8 24.2 39.6 29.4 28.3 25.5 50.7 28.4 27.3 51.3 77.0 16.7 24.5 23.7 31.2 22.2 29.2 21.0 33.5 32.5 46.2 22.7 23.3 33.9 18.9 16.9 17.0 25.7 26.6 56.9 25.7 39.9 35.3 58.6 17.0 33.8 31.5 44.1 15.3 67.2 13.0 17.9 13.7 9.2 13.8 12.3 11.1 11.9 10.1 10.0 14.4 9.5 15.8 8.0 16.7 12.6 12.8 13.3 16.3 15.9 12.5 13.1 12.6 12.7 12.3 12.2 13.4 14.7 12.1 22.4 5.5 45.7 13.0 23.6 18.2 13.0 18.2 23.7 12.3 13.5 101.2 8.6 11.3 9.2 29.2 20.7 14.4 5.7 11.7 17.7 560.6 18.3 16.7 15.8 10.8 25.6 74.5 17.6 27.1 19.8 10.2 13.2 21.5 16.3 13.2 7.0 19.7 37.0 75.2 7.6 14.2 16.0 17.2 242.7 16.8 12.6 12.4 35.6 13.4 30.3 8.2 168.9 45.6 19.4 1.9 20.7 12.3 11.5 7.4 13.5 18.8 16.3 6.6 14.3 17.9 83.7 19.7 24.6 33.8 23.7 17.2 12.1 7.0 24.0 LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 629.8;Paneth cells: 584.1;Proximal enterocytes: 931.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 862.9;SK-BR-3: 2270.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" NA NA 7100000000 "Cluster 32: T-cells - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000410: , HPA000554: AB_1079246" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.63e-3)" "unprognostic (1.62e-2)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (1.57e-2)" "unprognostic (4.55e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (1.58e-1)" "unprognostic (1.65e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" 192.8 218.6 51.2 75.0 91.4 48.6 109.5 95.6 62.3 188.8 159.8 210.8 312.9 121.4 45.2 114.2 155.6 240.8 311.4 46.6 81.4 103.1 68.5 182.8 52.7 145.6 88.3 155.6 79.1 107.8 134.9 147.0 116.8 114.3 92.6 10.0 498.7 154.2 20.0 54.0 260.9 80.2 104.3 76.8 315.6 70.1 89.8 48.8 102.0 20.4 25.3 125.0 119.0 152.5 499.0 255.3 7.2 11.2 157.3 181.4 147.9 55.7 49.0 371.3 725.7 107.5 862.9 2.8 372.7 33.5 361.7 200.1 53.6 203.7 11.5 1.2 319.0 33.8 206.0 481.0 387.7 0.4 31.6 305.8 111.5 197.5 12.6 83.8 9.9 68.7 3.4 1.5 87.7 62.8 151.2 6.0 13.0 163.7 170.7 100.1 209.9 4.8 155.5 352.6 235.1 267.4 52.7 2270.3 754.5 14.0 57.5 16.1 16.3 245.5 169.8 7.1 225.8 0.8 2.2 3.7 332.1 96.8 263.7 0.8 17.7 4.9 12.0 27.2 25.0 4.7 43.3 17.9 7.6 2.4 68.4 33.0 1.2 9.4 14.7 0.6 26.0 25.1 51.2 91.4 95.6 62.3 46.6 81.4 145.6 88.3 116.8 104.3 89.8 152.5 88.0 189.1 144.3 9.8 5.6 31.1 146.8 462.5 60.3 37.2 60.5 43.1 180.7 127.2 306.2 139.8 6.2 179.1 3.4 629.8 17.6 275.0 7.2 77.4 118.7 26.8 168.2 4.4 0.3 136.5 336.0 284.6 257.9 126.9 13.3 316.5 46.8 45.8 88.3 74.0 5.3 328.7 309.3 36.8 23.7 37.1 282.7 36.0 81.8 8.4 27.9 80.8 2.1 11.6 33.9 132.4 584.1 266.3 3.5 72.4 931.4 49.2 123.9 24.3 177.5 80.5 119.6 4.5 2.1 83.8 27.3 108.9 15.4 228.3 400.5 128.2 LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.0;Late spermatids: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favorable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" 5.4 7.5 5.9 3.0 6.5 6.6 5.7 7.6 9.8 5.1 5.9 6.4 5.5 4.6 5.3 6.7 6.1 3.6 11.1 6.2 6.7 8.7 8.6 2.9 5.1 6.3 6.4 10.0 6.8 6.5 4.0 3.3 6.8 4.1 6.4 5.4 4.3 3.1 27.2 5.7 5.2 5.2 5.5 3.6 6.3 9.8 6.2 4.3 4.2 21.0 4.2 5.8 4.7 8.3 5.7 4.5 5.4 5.2 11.5 11.4 4.8 6.6 3.7 6.1 4.1 6.8 7.8 20.8 7.3 2.5 15.2 4.9 15.9 9.1 8.0 2.4 4.0 8.8 2.3 7.0 10.4 19.1 5.5 10.8 14.6 7.1 22.4 13.4 7.0 12.7 21.1 5.2 7.5 3.6 10.9 24.9 7.3 15.3 14.2 9.1 15.2 12.9 7.1 2.9 6.0 4.8 3.8 4.9 22.5 7.6 5.6 8.8 2.6 4.7 10.6 6.3 15.5 9.9 15.8 14.3 7.2 22.2 4.0 2.5 6.4 3.9 5.7 7.6 12.7 10.0 8.1 8.0 6.2 7.6 16.2 11.6 3.4 7.7 5.6 5.5 5.7 4.7 5.9 6.5 7.6 9.8 6.2 6.7 6.3 6.4 6.8 5.5 6.2 8.3 11.0 9.6 12.6 14.0 12.9 9.7 11.6 17.4 12.0 25.8 15.7 17.3 20.1 17.2 12.7 18.4 10.4 24.0 22.6 12.9 21.5 13.2 86.0 11.2 15.8 10.3 18.1 12.4 11.9 6.4 18.2 10.4 9.2 10.3 17.7 19.0 11.4 19.0 17.5 10.1 18.8 13.5 18.3 13.5 7.8 100.1 10.2 11.4 1.8 6.5 17.6 15.4 16.5 14.6 22.9 10.3 10.1 12.4 5.8 6.6 18.3 32.6 14.1 26.7 0.0 10.8 20.5 64.9 25.1 13.7 9.2 9.6 14.2 19.0 18.4 8.8 LINGO4 LRRN6D ENSG00000213171 "Leucine rich repeat and Ig domain containing 4" Q6UY18 1 151800264-151805419 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 21.3;tongue: 5.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebellum: 1.8;hypothalamus: 1.0;midbrain: 2.7;pons and medulla: 4.0;thalamus: 1.4" "Region enriched" "Detected in many" 7 "spinal cord: 19.7" HPA060781 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus, Vesicles" "HPA060781: AB_2684361" "unprognostic (2.71e-2)" "unprognostic (1.98e-1)" "unprognostic (1.33e-3)" "unprognostic (1.96e-1)" "unprognostic (8.65e-2)" "unprognostic (3.16e-2)" "unprognostic (1.49e-5)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (2.39e-1)" "unprognostic (1.94e-4)" "unprognostic (6.92e-2)" "unprognostic (3.94e-4)" "unprognostic (3.84e-1)" "unprognostic (1.65e-1)" "unprognostic (7.06e-2)" "unprognostic (5.60e-2)" 0.0 2.0 0.1 0.1 0.1 0.0 0.1 4.1 0.2 0.1 0.1 0.1 0.1 0.0 0.8 0.1 0.7 0.1 0.7 0.3 0.5 0.3 1.1 0.2 0.2 2.8 1.6 0.0 0.4 0.5 1.4 0.0 3.9 0.7 0.1 0.1 0.6 0.2 21.3 0.6 0.2 0.0 1.3 0.1 0.4 0.6 1.6 1.2 0.6 5.6 0.2 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.2 0.3 0.5 2.8 1.6 3.9 1.3 1.6 2.1 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 LIPT2 ENSG00000175536 "Lipoyl(octanoyl) transferase 2" A6NK58 11 74490519-74493724 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.3" "Cell type enhanced" "Detected in many" "Early spermatids: 55.4;Late spermatids: 29.4;Proximal tubular cells: 17.7;Spermatocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040249 Approved NA NA "Cluster 30: Non-specific - Translation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA040249: AB_10795275" "unprognostic (8.80e-2)" "unprognostic (9.67e-2)" "unprognostic (5.12e-3)" "unprognostic (1.09e-1)" "unprognostic (6.74e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-2)" "unprognostic (8.96e-2)" "unprognostic (1.11e-2)" "prognostic favorable (1.63e-4)" "unprognostic (6.11e-2)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (9.45e-2)" "unprognostic (1.01e-1)" "unprognostic (1.51e-2)" "unprognostic (1.35e-1)" 1.3 2.0 1.8 1.6 2.0 2.1 2.4 1.8 1.8 1.5 1.2 2.1 3.7 1.6 3.2 1.8 3.2 1.9 1.5 1.6 1.8 4.6 3.1 1.7 2.2 2.4 1.9 3.4 2.9 2.1 2.1 2.1 2.4 1.8 2.3 1.9 2.1 2.7 8.0 1.6 3.6 0.6 1.8 2.1 3.5 12.3 2.8 2.7 3.0 7.1 2.2 1.7 1.2 3.3 2.1 3.3 6.6 3.1 2.1 0.4 6.9 0.8 1.5 3.3 2.3 9.8 3.0 11.5 4.0 0.6 8.0 3.2 2.8 1.9 1.2 2.2 2.6 4.0 3.2 2.9 2.9 4.4 5.0 1.4 2.2 2.2 2.2 1.5 0.2 12.7 3.0 4.1 1.3 4.0 6.6 6.1 4.9 13.0 2.6 4.3 7.0 3.7 2.6 7.3 5.5 3.6 5.6 2.0 8.1 6.2 5.6 3.2 0.6 1.0 2.1 1.5 1.8 5.7 5.8 9.3 0.6 2.7 2.9 0.1 4.7 7.5 5.5 3.0 7.6 10.6 7.3 6.6 5.3 10.5 13.3 10.9 1.1 8.4 3.4 6.3 3.7 4.8 1.8 2.0 1.8 1.8 1.6 1.8 2.4 1.9 2.4 1.8 2.8 3.3 0.6 0.0 0.0 1.0 2.5 0.8 1.1 2.9 4.0 0.9 1.7 1.9 1.1 2.8 1.4 3.7 0.0 13.2 0.7 0.9 5.9 2.6 55.4 1.5 0.7 1.0 0.0 4.0 0.3 4.4 14.1 1.4 2.0 1.1 0.0 1.9 2.2 4.2 5.4 3.3 0.2 3.1 4.1 1.3 0.0 29.4 1.8 2.3 1.8 0.0 0.7 9.8 2.1 0.5 1.1 2.8 0.5 1.2 0.8 1.0 4.3 17.7 1.9 1.6 0.0 1.3 0.9 46.7 10.7 2.9 0.6 8.1 1.4 3.0 3.1 0.3 LMAN1L "ERGIC-53L, ERGL" ENSG00000140506 "Lectin, mannose binding 1 like" Q9HAT1 15 74812716-74825757 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 31.7;lymphoid tissue: 25.7;prostate: 60.9;salivary gland: 20.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Late spermatids: 2.6;Prostatic glandular cells: 10.9;Spermatocytes: 7.3;Spermatogonia: 2.4" "Cancer enriched" "Detected in single" 45 "prostate cancer: 2.2" "Region enhanced" "Detected in many" "cerebellum: 13.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.4" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "unprognostic (4.51e-1)" "unprognostic (2.44e-1)" "unprognostic (4.26e-2)" "unprognostic (3.09e-1)" 0.0 1.8 0.0 0.2 0.8 0.0 0.0 13.3 0.5 0.1 0.0 0.1 0.1 0.0 0.3 0.6 0.0 0.0 31.7 0.2 0.1 0.0 0.0 0.0 0.3 2.3 0.7 0.0 0.0 0.0 0.2 0.0 2.1 60.9 0.1 4.2 20.7 0.0 0.1 0.1 0.3 0.0 2.1 25.7 4.6 1.2 0.3 0.1 0.0 0.0 0.1 0.1 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 13.3 0.5 0.2 0.1 2.3 0.7 2.1 2.1 0.3 3.5 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.1 0.0 1.3 0.0 0.0 0.4 7.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 778.4;skeletal muscle: 933.7;tongue: 793.6" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 1432.4" "Group enriched" "Detected in some" 20 "head and neck cancer: 3.5;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: AB_2681321" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (5.50e-1)" "unprognostic (5.69e-2)" "unprognostic (6.98e-2)" "unprognostic (2.13e-2)" "unprognostic (1.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (1.82e-3)" 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 21.2 0.0 0.1 778.4 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.8 0.0 10.2 0.0 0.1 10.0 0.0 933.7 0.4 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 793.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1432.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.5 0.4 9.4 0.0 0.0 0.1 0.0 0.1 27.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.9 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LMOD3 ENSG00000163380 "Leiomodin 3" Q0VAK6 3 69106065-69123032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 111.2;skeletal muscle: 459.8;tongue: 228.2" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 278.1" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 1.6" "Region enriched" "Detected in single" 4 "midbrain: 2.3" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 4 "HSkMC: 2.9" "Not detected" "Not detected" HPA036034 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA036034: AB_10673494" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (2.50e-3)" "unprognostic (1.96e-2)" "unprognostic (2.77e-2)" "unprognostic (1.39e-1)" "unprognostic (6.57e-2)" "unprognostic (3.63e-1)" "unprognostic (4.33e-1)" "unprognostic (2.98e-4)" "unprognostic (3.67e-3)" "unprognostic (1.29e-1)" "unprognostic (8.86e-2)" "unprognostic (2.96e-1)" 0.2 0.1 0.3 0.2 0.4 0.2 0.1 0.3 0.5 0.1 0.2 0.1 0.2 0.0 0.2 6.4 0.0 0.3 111.2 0.3 0.3 0.1 0.1 0.5 0.2 0.3 2.3 0.0 0.4 0.0 0.9 0.5 0.3 3.8 0.1 1.3 9.0 0.4 459.8 0.2 0.2 0.1 0.1 0.7 0.4 0.1 0.2 0.1 0.1 228.2 0.0 0.8 0.1 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.3 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.2 1.6 0.2 0.4 0.2 0.2 0.2 0.3 0.4 0.3 0.1 0.3 0.3 0.4 0.4 0.2 0.4 0.2 0.4 0.1 0.3 0.4 0.3 0.5 0.3 0.3 0.3 2.3 0.3 0.1 0.2 0.5 0.5 0.0 0.0 0.3 6.2 2.3 1.5 2.1 0.0 5.0 2.4 1.8 278.1 5.7 1.3 0.0 39.6 0.8 10.0 2.4 0.0 1.0 1.6 3.4 1.2 2.4 0.0 0.0 0.1 0.0 2.1 8.2 0.0 10.0 17.8 0.5 0.7 1.2 0.7 6.7 2.0 1.9 6.1 2.2 28.1 0.5 0.3 2.2 12.4 0.0 3.9 1.0 13.4 0.0 0.3 1.1 0.2 1.2 0.9 2.6 6.1 0.4 0.3 18.1 0.0 33.1 3.4 0.6 0.1 0.8 1.4 0.4 8.2 0.9 1.1 2.5 LRMDA "C10orf11, CDA017, OCA7" ENSG00000148655 "Leucine rich melanocyte differentiation associated" Q9H2I8 10 75431624-76560168 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation Albinism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 61.5;epididymis: 59.5" "Cell type enhanced" "Detected in many" "Adipocytes: 42.4;Distal tubular cells: 33.2;Endometrial ciliated cells: 27.8;Hofbauer cells: 56.9;Proximal tubular cells: 113.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 57.6;eosinophil: 22.1;intermediate monocyte: 28.8;myeloid DC: 67.5;non-classical monocyte: 17.1" "Group enriched" "Detected in many" 7 "dendritic cells: 67.5;granulocytes: 22.1;monocytes: 57.6" "Cell line enhanced" "Detected in many" "Hep G2: 46.3;HMC-1: 34.0;NB-4: 65.6;SK-MEL-30: 93.0;THP-1: 48.7;U-937: 43.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047446, HPA050419" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA047446: AB_2680050, HPA050419: AB_2756316" "unprognostic (1.04e-1)" "unprognostic (8.03e-2)" "unprognostic (2.40e-1)" "unprognostic (7.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (8.57e-3)" "unprognostic (5.86e-2)" "unprognostic (6.80e-2)" "unprognostic (8.34e-2)" "unprognostic (1.26e-1)" "unprognostic (7.34e-3)" "unprognostic (7.26e-2)" "unprognostic (6.50e-2)" "unprognostic (4.98e-3)" "unprognostic (3.64e-2)" 16.1 61.5 8.0 5.4 8.6 27.5 10.3 7.7 7.7 12.0 4.7 8.1 5.8 6.4 59.5 7.5 9.7 10.2 13.3 7.8 8.4 20.6 35.8 12.8 5.2 11.5 9.6 13.0 24.9 20.6 10.1 12.7 11.8 10.7 7.2 2.4 9.2 10.0 2.7 3.1 4.5 9.0 10.2 10.5 16.8 3.7 10.9 4.1 18.6 4.8 5.1 11.4 4.5 11.5 0.3 5.7 0.2 0.1 2.9 3.5 0.1 0.7 0.0 0.3 0.5 7.6 13.4 0.0 25.8 0.0 0.1 0.3 0.0 0.0 0.1 0.5 1.6 1.6 2.9 46.3 1.1 9.4 34.0 1.4 1.0 0.6 0.1 5.5 0.8 0.1 0.0 1.4 0.1 1.0 0.1 65.6 0.3 3.9 2.2 0.1 0.2 0.1 0.6 8.3 0.3 0.4 8.1 0.0 93.0 0.2 0.5 48.7 0.9 0.3 3.1 2.4 5.3 0.4 0.2 0.2 22.6 43.6 11.3 6.4 57.6 22.1 0.1 28.8 0.3 0.1 0.0 0.0 67.5 0.1 0.1 0.1 3.2 7.1 17.1 0.5 0.2 18.9 8.0 8.6 7.7 7.7 7.8 8.4 11.5 9.6 11.8 10.2 10.9 11.5 42.4 22.4 19.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 5.7 0.0 0.0 3.7 12.9 0.0 1.1 0.8 0.0 33.2 16.6 0.0 27.8 2.5 13.2 0.0 0.0 0.0 15.8 0.8 4.5 0.0 10.0 7.6 16.1 0.0 0.0 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.1 0.0 0.0 113.4 6.6 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 1.2 0.6 25.7 0.0 0.0 LRRC10 "HRLRRP, LRRC10A" ENSG00000198812 "Leucine rich repeat containing 10" Q5BKY1 12 69608564-69610907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "heart muscle: 40.0" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 39.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (3.76e-4)" "unprognostic (4.59e-1)" 0.1 0.0 0.2 0.3 0.2 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 40.0 0.2 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.4 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRRC2 ENSG00000163827 "Leucine rich repeat containing 2" Q9BYS8 3 46515385-46580099 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 45.3;skeletal muscle: 165.0;tongue: 94.1" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 198.4" "Cancer enhanced" "Detected in some" "thyroid cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 7.2;HEL: 4.2;LHCN-M2: 4.1;TIME: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039138, HPA064844" Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Nuclear bodies, Cytosol" "HPA039138: AB_10795461, HPA064844: " "unprognostic (1.32e-4)" "unprognostic (3.44e-3)" "unprognostic (2.29e-2)" "unprognostic (3.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.44e-1)" "unprognostic (7.38e-3)" "unprognostic (1.61e-1)" "unprognostic (7.42e-2)" "unprognostic (1.45e-1)" "unprognostic (3.72e-3)" "unprognostic (2.17e-1)" "unprognostic (2.23e-2)" "unprognostic (1.09e-1)" "unprognostic (2.53e-1)" "unprognostic (1.96e-2)" "unprognostic (1.24e-1)" 2.4 0.7 1.5 0.7 3.6 0.8 1.9 1.1 2.8 3.5 0.2 1.9 0.7 4.8 2.4 1.4 2.4 3.0 45.3 2.7 0.1 4.5 5.6 1.2 0.5 0.4 0.4 5.2 1.1 0.9 1.2 0.9 0.3 2.1 1.6 0.3 2.2 0.3 165.0 1.9 0.8 4.0 0.2 2.8 1.8 0.8 0.1 3.2 22.1 94.1 0.7 2.3 2.0 1.4 0.1 0.0 0.1 0.1 0.6 1.4 0.1 0.5 1.0 0.3 0.5 0.0 0.1 0.2 0.1 7.2 0.0 0.1 2.5 0.0 0.9 0.3 0.0 4.2 0.3 0.0 0.1 0.1 0.0 0.1 0.0 2.8 0.0 2.3 0.1 0.5 0.0 0.2 4.1 0.0 0.5 0.1 1.0 0.3 0.1 0.1 0.0 0.2 0.0 0.2 0.3 0.8 0.5 0.1 1.0 0.7 0.1 0.5 3.2 0.1 0.3 1.6 1.1 0.2 0.2 1.9 0.1 0.1 0.9 0.6 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.5 0.2 0.1 0.1 0.5 0.1 1.5 3.6 1.1 2.8 2.7 0.1 0.4 0.4 0.3 0.2 0.1 1.4 1.6 9.6 1.1 2.0 0.2 1.9 1.1 0.6 0.6 0.1 0.8 1.3 198.4 7.2 0.0 1.8 0.0 0.1 0.0 0.2 9.8 0.6 2.3 0.3 1.6 4.0 3.0 0.0 12.5 1.0 0.0 11.9 3.1 0.4 10.2 2.5 5.0 10.2 2.0 0.0 11.2 1.8 0.0 0.8 5.7 2.9 0.6 0.6 10.6 3.7 0.0 0.4 0.0 3.5 0.7 1.0 0.4 0.0 3.0 0.6 0.0 0.8 0.7 0.2 0.0 32.7 2.6 0.6 0.7 0.0 2.4 0.1 2.1 7.9 1.9 0.4 LRRC49 FLJ20156 ENSG00000137821 "Leucine rich repeat containing 49" Q8IUZ0 15 70853239-71053658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 56.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.0;Cardiomyocytes: 145.1;Early spermatids: 92.8;Excitatory neurons: 79.1;Inhibitory neurons: 88.4;Late spermatids: 105.3;Spermatocytes: 91.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 24.2;SH-SY5Y: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015596 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA015596: AB_2669230" "unprognostic (9.74e-2)" "unprognostic (7.94e-2)" "unprognostic (3.25e-3)" "unprognostic (1.15e-2)" "unprognostic (6.10e-2)" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (1.72e-1)" "unprognostic (3.36e-2)" "unprognostic (9.43e-2)" "unprognostic (7.66e-4)" "unprognostic (3.02e-1)" "unprognostic (5.29e-2)" "unprognostic (7.60e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.09e-2)" 2.4 2.8 7.9 0.8 10.4 0.3 2.7 13.7 11.2 6.6 7.3 3.9 0.4 8.7 29.6 1.9 9.0 3.7 56.3 6.7 10.7 4.6 0.5 2.7 0.7 12.2 10.5 11.1 1.4 9.1 11.6 1.0 13.2 5.3 1.7 26.8 1.8 4.8 1.1 1.7 1.7 5.0 5.1 0.8 2.7 11.9 18.8 1.0 4.8 1.7 0.8 4.5 3.8 6.1 2.1 3.9 8.5 14.9 3.8 6.4 0.1 3.6 6.3 2.4 5.8 1.3 1.6 0.0 2.6 1.5 6.0 3.5 8.4 4.3 2.0 0.0 4.5 1.0 4.1 0.1 24.2 0.1 0.5 2.9 1.5 7.2 12.3 12.5 6.5 0.0 0.1 0.0 3.6 0.7 0.0 0.7 5.0 0.3 2.8 0.0 5.7 0.0 8.0 4.5 17.2 18.0 4.3 2.0 4.0 3.1 4.6 1.4 5.9 2.9 9.0 5.4 6.2 1.1 4.3 0.0 6.8 0.2 2.2 0.1 0.0 0.0 0.1 0.3 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 10.4 13.7 11.2 6.7 10.7 12.2 10.5 13.2 5.1 18.8 6.1 4.3 3.2 3.7 63.3 0.7 2.3 22.9 11.5 5.7 85.0 2.2 3.0 145.1 1.5 13.0 7.3 62.6 0.1 0.1 1.5 5.9 7.0 92.8 30.8 8.0 7.2 18.5 0.0 79.1 0.9 0.1 11.6 2.6 4.3 0.0 8.0 2.5 0.0 0.1 30.3 88.4 1.9 0.0 0.3 0.7 105.3 5.6 0.7 0.0 19.7 0.0 10.9 0.0 63.8 34.1 1.7 1.6 9.8 0.2 11.7 0.3 3.5 54.8 37.3 0.0 7.4 8.0 91.9 11.4 0.7 1.6 0.3 0.8 2.5 1.2 8.0 LRRC53 ENSG00000162621 "Leucine rich repeat containing 53" A6NM62 1 74469376-74512611 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 1.0" "Cell type enriched" "Detected in single" 8 "Enteroendocrine cells: 6.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA054062 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA054062: AB_2682364" "unprognostic (3.67e-1)" 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.5 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRSAM1 "CMT2P, FLJ31641, RIFLE, TAL" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451489-127503499 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 32.0;Excitatory neurons: 28.6;Inhibitory neurons: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB037304: AB_2138198, HPA021403: AB_1853366, HPA021844: AB_1853368" "unprognostic (8.83e-2)" "unprognostic (3.13e-1)" "unprognostic (7.48e-3)" "unprognostic (4.15e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (5.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-2)" "prognostic favorable (6.78e-6)" "unprognostic (1.27e-1)" "prognostic favorable (5.72e-4)" "unprognostic (1.94e-2)" "unprognostic (3.26e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-2)" 7.2 9.8 8.6 3.4 8.6 2.0 7.3 7.3 12.5 10.7 5.2 16.5 3.4 9.0 5.9 8.7 7.8 3.9 17.3 8.8 8.8 9.0 8.8 7.4 4.5 11.1 7.6 10.7 5.7 6.9 9.0 3.4 11.4 9.1 2.6 2.3 7.5 5.6 13.5 21.2 9.1 5.0 7.0 9.5 9.5 4.3 7.9 3.4 8.8 7.2 3.2 12.3 10.2 9.0 5.7 10.8 4.8 10.7 9.8 9.1 8.3 5.3 8.1 10.0 7.6 8.9 5.9 9.8 5.9 9.9 3.6 18.7 7.8 13.3 3.8 11.5 5.3 5.2 9.0 10.2 9.4 6.2 7.3 6.1 7.9 6.1 12.2 10.7 11.2 7.6 4.8 7.6 4.5 17.6 3.9 4.5 4.7 17.4 9.3 7.1 5.6 18.4 11.5 5.1 9.8 9.2 4.1 12.6 8.8 4.3 26.5 3.2 10.2 4.6 5.6 4.2 2.5 6.2 7.9 1.1 9.1 4.5 2.6 18.5 4.8 21.3 3.7 6.5 4.7 3.7 2.8 3.5 6.1 2.7 1.1 1.4 4.0 1.3 6.8 3.6 2.3 3.8 8.6 8.6 7.3 12.5 8.8 8.8 11.1 7.6 11.4 7.0 7.9 9.0 5.3 9.6 3.9 32.0 5.1 1.1 3.1 2.9 4.6 6.7 5.2 5.0 20.4 4.3 7.3 0.0 6.2 5.0 5.3 6.0 5.9 7.1 0.6 3.6 4.7 4.8 1.2 2.5 28.6 1.4 2.1 4.9 12.2 4.6 9.5 6.6 3.3 7.1 6.3 11.8 26.9 5.8 14.2 5.6 3.7 1.2 2.8 7.4 3.6 10.3 7.4 4.7 3.1 18.1 21.0 4.7 5.0 5.3 3.9 5.0 6.6 5.8 6.0 5.2 0.0 5.1 6.0 5.7 3.6 5.8 2.7 7.0 5.6 3.9 4.8 3.3 LYNX1 SLURP2 ENSG00000180155 "Ly6/neurotoxin 1" P0DP58 8 142771197-142777810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.8;heart muscle: 79.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 34.8;Cardiomyocytes: 76.0;Club cells: 110.5;Excitatory neurons: 35.3;Hepatocytes: 34.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "intermediate monocyte: 6.6;non-classical monocyte: 17.5" "Lineage enriched" "Detected in many" 17 "monocytes: 17.5" "Cell line enhanced" "Detected in many" "BJ: 7.9;fHDF/TERT166: 8.9;GAMG: 11.4;HHSteC: 8.3;HSkMC: 7.5;OE19: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 51: Monocytes - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (8.67e-2)" "unprognostic (6.96e-2)" "unprognostic (1.31e-2)" "unprognostic (2.79e-3)" "unprognostic (1.04e-3)" "unprognostic (5.13e-3)" "unprognostic (1.33e-1)" "unprognostic (5.55e-3)" "unprognostic (1.12e-1)" "unprognostic (3.61e-3)" "unprognostic (7.21e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.82e-4)" "unprognostic (2.02e-2)" "unprognostic (2.28e-1)" "unprognostic (1.64e-2)" "unprognostic (1.85e-1)" 11.2 28.5 11.4 3.5 22.1 0.3 10.4 3.0 136.8 13.2 0.0 18.6 4.0 19.7 4.9 20.8 18.8 9.1 79.0 79.6 7.1 14.4 35.0 9.2 1.8 47.0 14.8 12.8 10.1 28.4 15.0 2.9 41.2 17.5 2.5 7.0 17.3 13.4 6.2 23.9 6.4 11.2 0.0 13.1 11.4 3.1 33.3 0.8 9.4 11.5 2.1 15.0 13.5 56.7 0.1 5.6 0.3 0.0 2.2 0.3 0.1 7.9 0.6 1.1 1.3 0.3 1.3 0.0 3.9 8.9 11.4 1.5 0.2 0.0 0.3 0.0 0.2 0.0 0.2 1.4 8.3 0.0 3.8 7.5 1.3 2.3 0.0 0.2 0.9 0.0 0.0 0.3 0.8 0.0 0.0 0.1 1.9 7.8 0.1 0.0 0.0 0.0 3.0 0.0 0.6 4.5 0.6 6.1 0.0 3.5 6.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 6.6 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.1 0.0 0.0 17.5 0.0 0.0 0.3 11.4 22.1 3.0 136.8 79.6 7.1 47.0 14.8 41.2 0.0 33.3 56.7 2.5 0.0 0.0 8.8 0.3 5.7 1.1 34.8 0.6 8.7 7.8 3.8 76.0 4.3 110.5 0.0 0.0 0.2 0.1 0.0 3.9 1.0 0.3 0.1 1.5 5.8 0.0 2.7 35.3 0.4 0.3 6.1 1.1 0.1 1.3 1.1 15.4 34.5 3.5 21.9 22.0 0.2 16.2 3.2 3.6 1.2 5.0 1.7 5.4 8.4 0.4 12.3 0.0 7.1 12.9 0.3 0.0 8.2 0.1 1.0 0.0 2.7 26.6 6.3 6.6 6.9 18.9 0.7 1.9 30.7 33.2 0.5 0.3 2.4 0.0 3.1 LYPLAL1 Q96AV0 ENSG00000143353 "Lysophospholipase like 1" Q5VWZ2 1 219173869-219212865 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 209.4;Proximal tubular cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045806 Approved Supported Cytosol NA NA 8600 "Cluster 30: Non-specific - Translation" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA045806: AB_10966647" "unprognostic (1.27e-2)" "unprognostic (1.29e-1)" "unprognostic (3.98e-2)" "unprognostic (8.64e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (2.01e-1)" "unprognostic (3.73e-2)" "unprognostic (4.08e-2)" "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (2.76e-2)" "prognostic favorable (1.31e-4)" "unprognostic (1.68e-1)" "unprognostic (5.87e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-2)" 9.3 17.9 7.5 3.8 7.6 1.1 10.0 7.8 11.3 8.5 7.2 5.6 8.6 7.3 3.6 7.9 5.4 8.6 36.5 7.3 8.5 42.3 27.3 7.0 8.6 7.9 7.5 9.8 7.6 11.8 5.8 8.2 7.9 13.2 5.9 6.5 8.5 6.5 7.4 9.6 7.5 7.8 8.0 4.4 6.1 6.5 7.4 5.8 16.2 12.1 7.7 6.0 3.9 8.8 9.1 9.4 4.1 0.0 8.1 16.3 10.3 5.3 5.9 4.8 5.6 4.3 12.9 10.0 13.9 4.5 4.7 4.9 8.6 12.1 7.3 13.7 9.3 5.8 4.9 9.8 32.9 12.6 4.3 19.5 11.1 4.8 12.1 11.3 14.5 9.5 16.8 10.2 11.4 6.1 6.1 10.3 7.8 8.6 15.4 3.3 10.5 17.5 19.9 7.1 10.1 5.6 6.3 16.9 17.7 13.5 16.2 15.6 7.8 4.0 2.0 8.2 6.2 8.7 5.3 6.8 13.5 10.1 9.0 0.9 2.0 1.5 0.8 1.8 1.9 3.3 1.3 1.0 1.8 2.0 2.3 1.8 2.2 1.4 1.8 1.5 1.6 1.3 7.5 7.6 7.8 11.3 7.3 8.5 7.9 7.5 7.9 8.0 7.4 8.8 23.6 25.6 35.5 93.0 37.1 22.2 18.7 75.5 29.0 28.5 23.9 25.4 105.9 31.5 42.0 51.5 8.4 89.5 12.8 10.8 209.4 49.3 40.9 7.7 17.4 16.3 18.6 10.3 50.2 53.2 35.4 29.7 11.7 23.6 17.1 18.5 22.9 39.8 64.8 18.5 51.7 18.0 44.7 26.8 21.2 7.8 27.1 49.3 42.7 79.6 27.1 108.7 20.6 82.9 123.4 37.5 16.9 30.9 15.0 13.0 33.4 349.2 38.2 28.9 13.1 24.8 23.3 36.0 24.8 24.9 29.3 62.5 14.2 26.5 15.8 12.3 MAEL "CT128, FLJ14904, SPATA35" ENSG00000143194 "Maelstrom spermatogenic transposon silencer" Q96JY0 1 166975582-167022214 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 159.2" "Group enriched" "Detected in some" 4 "Early spermatids: 1324.3;Late spermatids: 406.1;Spermatocytes: 573.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "NTERA-2: 3.4" "Region enriched" "Detected in single" 5 "thalamus: 1.1" "Low region specificity" "Detected in all" HPA078602 Approved NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" "HPA078602: AB_2732386" "unprognostic (1.36e-1)" "unprognostic (7.01e-2)" "unprognostic (5.81e-2)" "unprognostic (3.15e-1)" "unprognostic (9.78e-2)" "unprognostic (3.08e-1)" "unprognostic (2.68e-3)" "unprognostic (4.99e-2)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (3.04e-1)" "unprognostic (8.88e-2)" "unprognostic (5.49e-2)" "unprognostic (1.26e-1)" "unprognostic (3.32e-1)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" 0.1 0.2 1.7 0.0 1.9 0.0 0.1 1.2 2.2 0.1 0.9 1.2 0.0 0.0 1.3 0.2 0.1 0.3 5.6 2.1 1.1 1.5 0.3 0.2 0.1 1.2 1.4 0.1 0.2 0.0 0.8 6.5 1.2 0.7 0.0 4.3 0.3 1.0 0.3 0.0 0.1 0.4 1.2 0.0 0.1 159.2 1.6 0.1 0.1 0.3 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 1.9 1.2 2.2 2.1 1.1 1.2 1.4 1.2 1.2 1.6 1.7 0.2 0.0 0.0 8.8 0.1 0.1 0.5 0.0 0.0 1.4 0.1 0.1 4.8 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 1324.3 0.0 0.0 1.3 0.0 0.0 11.5 0.2 0.4 4.8 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 3.9 0.0 0.0 0.0 0.3 406.1 10.8 0.8 0.0 1.0 0.0 45.3 0.0 8.0 3.3 0.0 0.0 10.1 0.0 0.2 0.0 5.6 0.0 1.5 0.0 3.4 0.4 573.7 156.3 0.0 0.0 0.3 0.2 0.2 0.0 0.2 MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 317.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 120.6;granulocytes: 137.8;Hepatocytes: 221.1;Peritubular cells: 95.2;Proximal enterocytes: 178.8;Proximal tubular cells: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 41.4;SiHa: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 110000 "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" 78.0 51.1 99.3 6.5 102.8 0.1 45.7 89.1 117.7 32.3 83.5 46.5 73.5 119.4 55.0 31.4 98.0 17.3 97.8 93.9 149.1 124.2 317.6 33.0 6.1 143.8 134.2 155.4 10.9 15.6 25.9 11.2 125.9 82.9 16.5 13.9 78.5 155.5 114.6 9.9 79.0 103.3 115.8 2.4 23.7 9.0 145.2 3.8 5.6 65.1 7.1 28.3 25.4 115.8 0.0 1.0 0.1 0.0 0.6 0.1 0.3 0.0 0.0 0.0 0.0 5.4 4.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 8.1 41.4 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.3 3.5 0.0 0.0 0.0 0.0 0.4 4.0 0.0 0.1 1.1 78.2 0.0 0.5 0.6 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 99.3 102.8 89.1 117.7 93.9 149.1 143.8 134.2 125.9 115.8 145.2 115.8 5.9 0.0 4.1 53.5 0.4 5.5 0.4 1.2 1.8 1.4 3.5 22.4 120.6 52.9 1.9 5.5 4.2 0.4 0.0 10.2 62.6 20.1 0.4 26.4 81.6 10.3 0.0 2.7 36.9 2.8 0.5 17.0 16.3 6.0 137.8 69.6 7.5 221.1 1.5 15.2 7.6 6.4 12.2 4.3 3.6 2.1 46.0 1.8 7.2 9.4 0.0 27.2 0.0 11.6 1.3 7.9 7.8 95.2 0.3 0.6 178.8 182.6 11.8 1.0 13.1 2.6 18.4 0.3 0.4 2.3 4.0 0.4 5.5 0.5 10.5 0.5 MAP7D1 "FLJ10350, FLJ39022, PARCC1, RPRC1" ENSG00000116871 "MAP7 domain containing 1" Q3KQU3 1 36155579-36180849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 286.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028075 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "HPA028075: AB_10603778" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (5.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.52e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.49e-6)" "unprognostic (6.00e-3)" "unprognostic (2.05e-1)" "unprognostic (3.57e-2)" "unprognostic (1.88e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (8.56e-6)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (9.32e-3)" 67.9 23.2 41.7 41.5 60.7 36.2 47.1 50.7 52.2 38.9 0.4 84.1 18.9 50.0 3.9 48.8 34.8 28.8 122.4 40.8 43.5 21.8 7.7 53.2 25.0 74.7 58.2 24.8 14.7 12.5 36.5 24.0 78.4 39.5 9.4 13.0 33.5 28.2 286.0 71.6 31.4 34.0 23.3 33.5 39.3 12.6 67.3 22.6 33.1 106.5 17.6 62.1 41.2 96.2 104.8 60.3 92.7 58.9 55.6 41.9 68.3 102.3 102.8 105.4 92.5 33.9 104.6 43.8 85.7 93.5 57.7 112.3 38.3 139.1 34.4 74.9 34.4 29.7 42.5 13.2 87.3 44.0 73.3 73.4 38.6 142.6 87.8 81.5 72.9 59.8 29.1 65.3 59.3 21.0 81.6 37.2 84.7 14.7 33.5 83.8 68.4 41.5 53.0 35.7 35.7 68.6 58.7 32.3 79.6 49.7 21.6 30.9 138.3 123.6 94.4 105.5 140.6 64.4 20.6 52.5 105.8 29.7 75.9 0.1 0.4 0.4 0.3 0.2 0.4 0.0 0.2 0.2 0.2 0.1 0.5 0.2 1.4 0.1 0.1 0.2 0.1 0.0 41.7 60.7 50.7 52.2 40.8 43.5 74.7 58.2 78.4 23.3 67.3 96.2 40.6 44.8 14.4 12.1 26.5 143.1 147.3 18.4 47.8 35.4 44.0 26.3 172.6 17.2 17.9 23.9 10.4 48.3 58.2 39.9 17.6 43.3 36.9 32.1 38.6 46.7 10.1 16.2 17.4 27.4 111.3 48.0 29.6 60.1 12.7 56.3 30.7 9.7 69.9 48.8 35.1 14.9 10.2 40.6 125.3 77.1 30.7 65.1 32.0 9.4 35.9 32.3 75.2 9.5 62.3 66.1 29.2 47.8 53.2 98.5 63.0 14.3 10.0 39.8 19.7 51.6 55.8 17.6 16.1 62.7 141.8 130.2 59.8 17.0 19.5 157.6 MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skeletal muscle: 79.0" "Cell type enhanced" "Detected in many" "Astrocytes: 142.4;Bipolar cells: 314.4;Early spermatids: 199.9;Excitatory neurons: 189.2;Horizontal cells: 361.7;Inhibitory neurons: 153.7;Late spermatids: 416.6;Muller glia cells: 145.7;Oligodendrocytes: 163.8" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "HDLM-2: 69.0;SCLC-21H: 21.1;T-47d: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" NA NA 7100 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" 4.7 4.3 26.2 0.3 27.1 0.0 9.1 8.3 67.7 2.4 0.0 8.4 0.5 1.0 0.2 8.4 1.0 0.8 9.4 30.0 20.4 14.7 0.6 0.8 0.3 11.6 11.4 0.6 1.5 2.9 29.5 3.4 22.4 5.4 0.3 17.6 8.5 3.4 79.0 6.3 1.8 0.3 2.7 0.4 1.7 20.3 14.8 0.4 0.9 27.4 0.2 10.2 2.3 19.7 2.9 0.5 0.3 6.4 0.3 0.9 1.8 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.4 0.5 0.1 2.3 0.3 0.0 69.0 3.4 0.0 0.3 4.2 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.1 0.0 4.4 0.7 3.6 0.0 7.7 1.0 0.2 0.2 0.7 2.0 0.0 4.0 8.5 0.0 9.1 21.1 9.1 2.5 0.0 1.8 1.0 34.7 0.1 0.1 0.3 0.8 1.7 0.3 0.9 0.3 0.0 0.6 2.0 0.5 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.0 0.7 0.0 26.2 27.1 8.3 67.7 30.0 20.4 11.6 11.4 22.4 2.7 14.8 19.7 1.9 0.0 9.8 142.4 1.0 1.0 1.4 0.2 1.2 314.4 26.7 21.2 35.2 0.0 0.1 1.8 64.6 0.2 0.4 0.1 7.9 0.5 199.9 0.4 1.7 1.8 0.0 0.0 189.2 0.4 9.1 3.7 0.5 1.3 4.5 1.6 1.1 0.5 0.3 361.7 153.7 0.0 2.0 0.6 1.7 416.6 2.8 0.8 5.4 8.4 0.7 145.7 0.0 129.7 163.8 0.6 0.0 2.6 0.1 2.5 0.1 76.1 0.0 28.3 0.0 28.2 6.0 18.4 8.1 22.7 3.3 0.3 1.5 0.8 0.3 0.6 MARCHF11 "MARCH-XI, MARCH11, RNF226" ENSG00000183654 "Membrane associated ring-CH-type finger 11" A6NNE9 5 16067139-16180762 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 82.4" "Cell type enriched" "Detected in single" 30 "Cardiomyocytes: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 83.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (9.91e-3)" "unprognostic (1.08e-1)" "unprognostic (2.98e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (1.52e-1)" "unprognostic (3.55e-2)" 0.1 0.7 4.7 0.0 4.6 0.0 0.3 5.0 6.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.7 6.7 0.2 0.1 0.0 0.0 5.7 4.7 0.3 1.3 0.0 9.9 0.0 5.0 0.3 0.0 3.6 1.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.1 82.4 4.8 0.0 0.0 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 83.8 0.0 0.0 0.0 7.5 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 4.6 5.0 6.7 5.7 6.7 5.7 4.7 5.0 3.8 4.8 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MCCC1 MCCA ENSG00000078070 "Methylcrotonoyl-CoA carboxylase 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 153.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008310 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA008310: AB_1853620" "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favorable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" 37.9 22.6 9.5 9.5 10.9 13.9 33.2 9.9 13.4 12.3 13.8 17.4 16.1 10.1 14.6 17.6 12.2 11.9 34.2 9.2 9.3 58.8 59.3 17.9 11.7 9.5 9.1 17.2 31.2 18.7 8.4 6.3 10.6 15.1 18.6 10.8 18.0 13.4 21.9 12.2 13.8 10.6 9.3 11.8 21.7 9.1 11.1 16.0 18.9 26.3 15.5 26.5 9.4 13.3 43.1 16.5 10.3 10.6 42.6 19.1 20.4 19.5 26.4 21.1 23.5 22.9 17.1 47.6 31.0 17.2 35.8 22.0 15.4 12.9 26.4 16.6 17.0 40.0 18.3 23.9 28.7 27.5 22.0 21.6 14.5 10.0 23.3 14.0 28.6 40.7 22.7 24.7 23.6 35.4 27.1 15.9 11.2 66.3 17.9 22.4 22.6 60.1 32.2 67.2 22.0 16.4 75.3 100.1 21.1 10.7 153.9 37.8 14.0 15.8 12.5 12.8 28.6 24.3 48.8 48.2 16.8 38.4 15.2 14.4 13.3 25.0 10.7 15.6 12.3 17.9 14.1 11.8 26.6 15.4 14.7 13.1 2.1 25.4 16.8 17.3 9.6 10.7 9.5 10.9 9.9 13.4 9.2 9.3 9.5 9.1 10.6 9.3 11.1 13.3 6.2 9.6 53.9 44.7 14.6 7.0 20.1 17.9 15.9 13.0 10.6 9.5 32.8 31.5 20.2 27.6 10.4 35.4 6.3 7.2 33.2 25.3 5.4 11.0 10.2 6.6 6.0 10.9 66.6 17.2 5.4 10.3 21.4 21.9 7.6 19.0 6.1 36.5 16.5 8.4 56.9 13.6 16.2 11.1 8.6 5.5 8.7 10.5 7.2 44.0 10.5 12.0 4.1 47.7 61.6 13.4 15.8 10.5 12.5 10.4 13.5 40.6 21.4 11.2 6.6 11.6 9.6 8.1 4.4 22.3 5.8 28.3 10.1 24.3 20.5 21.7 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.5" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 81.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 21.3 47.6 13.4 13.5 13.7 6.0 60.0 12.4 15.5 21.3 24.9 30.5 27.2 14.4 38.9 25.4 17.2 15.2 54.9 12.0 13.1 73.3 120.5 13.4 17.8 14.8 13.4 14.2 24.6 32.8 14.1 14.2 14.8 48.2 35.9 12.2 28.2 20.6 34.4 19.8 20.7 11.7 16.3 15.6 25.8 8.6 16.0 14.2 44.6 35.4 21.5 27.0 15.0 18.4 38.5 52.4 21.4 82.5 22.4 23.0 36.9 16.4 29.4 35.7 25.7 91.1 46.9 90.4 62.8 25.9 28.0 30.8 37.8 58.8 44.3 47.6 45.6 48.2 24.7 100.5 39.2 24.4 42.8 29.5 30.1 32.6 25.8 15.8 31.7 24.9 63.2 31.6 24.9 103.0 0.3 42.9 29.0 33.2 27.2 46.3 64.5 130.9 92.5 66.9 32.9 36.7 80.1 111.8 38.8 10.1 92.7 59.6 22.7 14.4 22.1 26.1 49.9 22.4 46.2 54.6 23.7 66.3 36.6 2.0 8.4 1.9 6.5 13.5 8.5 9.7 8.4 7.4 19.4 9.9 8.3 9.1 1.3 14.7 8.1 8.1 12.1 8.3 13.4 13.7 12.4 15.5 12.0 13.1 14.8 13.4 14.8 16.3 16.0 18.4 9.1 16.0 23.6 27.4 26.8 13.3 17.5 20.2 22.2 12.6 54.9 28.3 61.5 20.0 22.3 16.5 6.2 48.5 17.6 26.3 21.5 20.6 4.3 94.0 24.0 15.1 29.5 13.9 22.2 18.2 23.0 13.1 30.1 107.0 12.7 22.7 9.7 93.1 18.0 3.3 21.6 22.8 8.2 12.1 11.2 9.8 13.7 14.0 12.4 11.2 17.9 15.4 20.6 30.2 28.0 15.3 17.0 20.3 27.2 29.6 23.6 59.1 17.7 10.8 6.6 15.2 9.0 4.2 12.0 35.9 13.8 63.6 17.9 30.9 33.9 20.9 MCRIP2 "C16orf14, FAM195A, MGC15416" ENSG00000172366 "MAPK regulated corepressor interacting protein 2" Q9BUT9 16 636817-648474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 48.1;liver: 56.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 189.2;Distal tubular cells: 183.9;Hofbauer cells: 133.9;Proximal tubular cells: 310.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/84: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060363 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA060363: AB_2684263" "unprognostic (7.14e-2)" "unprognostic (3.85e-2)" "unprognostic (8.25e-2)" "unprognostic (2.49e-2)" "unprognostic (2.72e-1)" "unprognostic (4.18e-2)" "unprognostic (1.60e-1)" "unprognostic (2.96e-3)" "unprognostic (7.82e-2)" "unprognostic (3.14e-1)" "unprognostic (2.19e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.06e-2)" "unprognostic (4.00e-2)" "unprognostic (2.10e-2)" "prognostic favorable (7.23e-4)" 9.0 31.4 5.1 2.1 4.8 1.7 5.2 7.0 8.6 4.0 17.3 21.0 6.8 4.0 0.0 8.6 4.3 0.5 48.1 4.8 4.3 25.5 56.1 5.7 0.8 4.6 4.4 4.3 12.5 2.6 12.7 2.2 5.0 8.1 0.9 0.1 8.8 1.5 39.2 2.9 10.7 0.3 3.8 9.5 14.6 5.6 6.3 0.3 7.3 3.3 0.6 9.4 4.3 3.6 14.7 3.4 0.4 6.0 1.3 3.7 7.1 7.8 2.4 3.8 2.1 3.9 6.8 23.9 18.8 0.7 2.2 15.0 2.4 6.0 0.1 19.0 30.4 10.6 3.5 3.1 6.8 18.2 14.4 2.2 5.4 1.7 2.0 1.4 1.3 6.3 23.6 3.0 0.7 4.4 1.7 30.0 9.2 7.5 37.1 25.9 0.1 34.5 3.1 1.1 15.3 7.7 13.9 9.9 26.0 0.3 8.8 14.4 6.1 0.3 7.8 8.6 10.9 37.6 47.0 35.9 1.4 15.8 0.9 0.0 11.3 3.1 1.2 12.9 3.1 10.5 3.3 3.7 10.0 6.8 4.2 2.8 0.2 2.5 14.5 0.3 3.9 3.5 5.1 4.8 7.0 8.6 4.8 4.3 4.6 4.4 5.0 3.8 6.3 3.6 11.3 3.2 12.4 0.0 10.0 0.0 0.0 0.0 0.0 0.0 55.5 53.8 0.0 0.0 1.8 64.4 0.0 189.2 7.9 0.0 183.9 62.7 0.0 17.3 13.1 4.6 0.0 0.0 0.0 70.8 27.6 7.5 0.0 16.9 5.1 51.1 0.0 0.0 133.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 40.3 0.0 0.0 0.0 0.0 67.4 0.0 0.0 1.7 0.0 0.0 310.2 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 79.6 6.3 50.3 0.0 0.0 ME3 ENSG00000151376 "Malic enzyme 3" Q16798 11 86441108-86672636 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 54.2;Excitatory neurons: 103.7;Inhibitory neurons: 147.8;Oligodendrocyte precursor cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 54.4;hTERT-RPE1: 64.1;HUVEC TERT2: 36.3;TIME: 40.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA038473 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA038473: AB_10672747" "unprognostic (1.83e-3)" "unprognostic (8.00e-2)" "unprognostic (1.99e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-1)" "unprognostic (2.91e-1)" "unprognostic (5.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "unprognostic (5.74e-2)" "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (2.73e-1)" "unprognostic (2.96e-2)" "prognostic favorable (3.86e-4)" 17.4 24.4 25.5 5.0 27.2 6.2 19.5 12.2 31.5 24.5 14.4 16.4 7.1 16.7 5.6 4.2 13.6 11.5 26.2 27.0 15.7 25.1 6.2 11.3 4.2 24.8 25.9 27.9 15.9 16.2 22.4 4.7 22.9 19.9 13.7 10.8 12.6 9.0 21.9 4.5 8.9 14.1 5.3 10.9 21.0 13.0 20.4 3.5 12.5 19.5 2.4 17.1 14.2 16.5 0.0 18.1 5.2 0.0 7.9 16.6 0.1 5.9 9.6 12.9 16.0 14.0 54.4 0.0 5.3 5.7 31.5 0.2 0.0 0.1 5.6 9.2 0.0 9.6 16.8 0.0 11.9 1.2 0.0 11.8 2.8 10.2 0.1 64.1 36.3 0.0 0.2 0.0 9.1 1.8 2.7 0.1 1.2 1.7 7.7 8.3 0.0 0.6 11.4 21.4 6.2 0.1 3.8 0.1 0.0 2.1 0.9 1.5 40.0 1.5 1.2 26.3 0.9 0.1 3.3 0.0 1.4 17.1 1.6 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.7 1.2 2.3 0.0 0.9 1.1 0.0 1.0 0.1 0.3 0.0 0.5 25.5 27.2 12.2 31.5 27.0 15.7 24.8 25.9 22.9 5.3 20.4 16.5 13.6 3.2 3.3 30.3 1.1 2.3 4.6 5.4 5.7 16.5 7.5 9.1 54.2 2.8 8.1 3.7 0.0 0.3 1.9 19.2 43.0 9.1 0.7 3.2 6.1 11.5 9.0 4.2 103.7 7.9 0.4 8.4 19.9 1.6 0.0 33.4 14.6 1.6 6.8 20.2 147.8 14.8 4.1 1.6 3.5 2.5 6.2 1.8 1.8 14.0 1.1 2.0 1.0 75.4 4.8 11.5 21.1 6.4 0.5 6.4 3.5 6.5 14.9 2.5 13.1 7.0 8.2 0.4 0.2 2.6 1.6 0.0 1.6 38.8 11.0 6.6 MECR "CGI-63, ETR1, FASN2B, NRBF1" ENSG00000116353 "Mitochondrial trans-2-enoyl-CoA reductase" Q9BV79 1 29192657-29230942 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.1" "Cell type enhanced" "Detected in all" "Late spermatids: 82.5;Rod photoreceptor cells: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022018, HPA022030, HPA028740" Enhanced Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA022018: AB_1853714, HPA022030: AB_1853716, HPA028740: AB_10601133" "unprognostic (2.53e-1)" "unprognostic (1.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.06e-2)" "unprognostic (8.66e-2)" "prognostic favorable (5.81e-6)" "unprognostic (7.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "prognostic unfavorable (5.29e-4)" 14.7 14.6 5.1 1.7 5.1 1.8 13.4 3.3 6.2 10.2 3.1 10.3 1.4 12.9 2.5 12.5 9.4 1.3 24.8 6.0 3.9 14.1 15.8 7.3 2.0 5.2 4.0 10.0 8.9 4.5 7.2 3.5 5.4 7.9 2.6 9.9 12.3 3.0 42.1 15.4 7.2 3.1 3.2 6.7 11.1 7.6 4.3 1.4 8.3 5.8 2.1 9.6 9.6 5.2 3.9 4.5 3.2 4.6 2.9 2.5 6.8 3.7 3.8 4.7 3.9 2.3 5.6 7.3 5.1 3.7 1.3 3.0 5.4 6.3 4.0 4.4 6.9 6.4 3.4 4.1 6.6 6.1 1.9 4.3 5.9 3.1 11.0 3.8 3.5 6.9 5.8 4.2 4.7 4.5 3.9 2.9 6.5 5.8 4.3 3.5 4.2 9.3 5.9 2.4 5.1 4.5 4.1 4.7 7.0 4.4 2.3 5.4 3.8 2.4 2.9 4.1 4.7 2.7 2.2 5.0 3.9 8.4 5.2 0.1 2.2 0.0 1.5 2.1 4.1 2.2 1.6 1.7 1.9 1.1 2.3 1.6 0.3 2.9 1.6 2.5 2.4 1.2 5.1 5.1 3.3 6.2 6.0 3.9 5.2 4.0 5.4 3.2 4.3 5.2 8.8 12.8 3.9 14.7 9.1 5.6 15.6 26.9 7.4 12.8 12.0 14.6 19.8 21.5 21.4 20.2 10.4 46.0 3.8 7.4 41.1 24.3 40.8 19.7 13.6 9.1 7.8 10.1 25.1 19.7 42.4 12.8 4.6 12.8 5.7 17.5 7.1 19.7 20.8 8.4 20.3 9.4 12.2 6.0 5.1 82.5 13.7 5.3 16.0 3.7 10.8 14.5 10.3 11.6 15.2 16.3 8.0 10.9 10.3 20.6 10.9 46.0 11.3 68.5 13.1 13.2 12.9 8.5 16.1 14.0 7.4 27.9 6.0 25.8 18.3 20.5 MED9 "FLJ10193, MED25" ENSG00000141026 "Mediator complex subunit 9" Q9NWA0 17 17476994-17493221 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056415 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Midbody "HPA056415: AB_2683120" "unprognostic (1.81e-2)" "unprognostic (4.58e-2)" "unprognostic (2.65e-1)" "unprognostic (3.48e-3)" "unprognostic (1.27e-1)" "unprognostic (2.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.21e-2)" "unprognostic (4.23e-1)" "unprognostic (7.65e-2)" "prognostic favorable (4.18e-5)" "unprognostic (3.96e-2)" "prognostic favorable (2.83e-9)" "unprognostic (2.26e-3)" "unprognostic (2.29e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-1)" 9.3 14.9 21.6 4.9 23.0 10.6 10.3 20.6 28.0 12.4 19.2 11.3 8.2 12.1 11.9 10.2 8.6 4.6 32.7 22.5 21.0 20.4 23.6 7.3 6.8 21.8 22.1 9.4 10.0 18.3 12.8 5.7 20.6 11.8 7.4 9.9 12.9 8.5 27.3 14.2 9.4 5.8 20.9 10.4 12.4 10.9 22.3 11.6 13.8 41.5 6.7 8.8 9.4 21.8 12.0 15.0 12.7 13.7 10.0 9.0 11.0 9.6 11.9 14.5 13.0 22.0 5.9 14.7 10.8 9.9 8.8 15.3 16.3 13.2 13.5 9.6 26.3 9.0 10.0 15.9 10.8 7.2 7.5 14.6 12.3 12.2 12.5 10.8 10.0 21.3 10.7 6.7 9.7 10.1 32.7 14.9 11.7 24.8 15.4 24.8 28.7 9.8 13.0 8.4 8.2 13.0 12.6 9.8 21.7 47.6 11.6 9.3 6.8 10.6 12.3 18.6 15.3 12.4 9.9 8.2 13.3 12.5 11.5 2.6 7.0 11.8 9.3 9.5 12.3 9.9 9.7 9.7 7.7 9.1 10.2 11.4 2.3 10.7 12.4 12.5 10.2 7.8 21.6 23.0 20.6 28.0 22.5 21.0 21.8 22.1 20.6 20.9 22.3 21.8 6.0 3.2 4.4 10.1 5.8 4.6 8.9 5.5 5.2 25.9 8.2 6.7 19.6 10.0 5.0 9.2 14.6 8.6 8.1 9.1 11.7 6.6 8.7 6.0 6.3 6.0 15.7 4.2 14.4 4.5 5.8 5.6 11.7 8.8 0.0 14.5 7.5 5.5 6.1 16.8 12.9 9.6 8.2 4.4 2.8 8.9 5.6 4.0 1.8 1.9 4.7 24.1 10.3 14.1 6.5 3.3 5.7 9.4 7.2 8.4 9.5 6.1 4.0 25.0 0.0 6.0 6.9 10.9 29.9 5.6 4.8 9.6 6.6 13.4 8.1 9.0 MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927028 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.0;testis: 3.7;thyroid gland: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 86.1" "Cancer enhanced" "Detected in some" "renal cancer: 0.9;testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: Testis - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.47e-1)" "unprognostic (9.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (9.70e-4)" "unprognostic (3.16e-1)" "unprognostic (2.86e-4)" "unprognostic (3.35e-2)" "unprognostic (4.17e-2)" "unprognostic (4.85e-2)" 0.1 0.7 0.4 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.2 0.6 4.0 0.8 0.0 0.0 1.0 0.5 0.0 2.0 0.1 1.0 0.0 1.2 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 3.7 0.6 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.2 0.2 0.6 1.0 0.5 1.2 0.5 0.6 0.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 86.1 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 21.3 0.3 0.0 0.0 9.4 0.0 0.6 0.0 2.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MESP1 "bHLHc5, MGC10676" ENSG00000166823 "Mesoderm posterior bHLH transcription factor 1" Q9BRJ9 15 89748661-89751310 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 4.5;prostate: 7.3;skeletal muscle: 4.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 52.2;Breast myoepithelial cells: 58.9;Distal enterocytes: 40.1;Exocrine glandular cells: 43.0;Spermatocytes: 41.5" "Cancer enriched" "Detected in many" 4 "prostate cancer: 26.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.5;HDLM-2: 3.1;HEK 293: 3.0;PC-3: 5.7;SCLC-21H: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069981 Supported Nucleoplasm,Nucleoli NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Nucleoli "HPA069981: AB_2686225" "unprognostic (4.17e-2)" "unprognostic (1.52e-2)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" "unprognostic (4.83e-2)" "unprognostic (7.21e-2)" "unprognostic (2.68e-2)" "unprognostic (4.95e-3)" "unprognostic (2.26e-2)" "unprognostic (2.47e-1)" "unprognostic (8.38e-2)" "unprognostic (2.06e-1)" "unprognostic (2.24e-3)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.10e-1)" "unprognostic (7.03e-2)" 4.5 1.4 2.4 0.0 2.7 0.1 3.0 1.7 3.5 0.5 0.5 1.4 0.1 0.1 0.0 0.3 0.2 0.0 1.3 2.7 2.1 0.7 0.8 0.2 0.0 1.7 1.5 0.2 1.2 0.2 1.0 0.0 1.9 7.3 0.0 0.2 2.1 0.1 4.5 0.2 0.5 0.0 1.2 0.1 0.5 1.3 2.6 0.0 0.5 0.3 0.0 0.3 0.4 2.0 3.5 1.3 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 1.3 0.0 0.4 0.0 0.2 0.0 0.0 3.1 3.0 0.1 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.1 0.5 0.8 0.0 0.0 5.7 0.1 0.0 0.8 0.0 0.0 2.6 0.1 0.7 1.1 0.8 0.0 0.0 0.4 0.0 0.0 0.2 2.0 0.6 1.3 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.7 1.7 3.5 2.7 2.1 1.7 1.5 1.9 1.2 2.6 2.0 1.7 0.0 1.1 2.6 2.9 0.3 2.8 5.1 0.6 11.6 52.2 58.9 6.3 17.2 33.9 1.8 10.4 3.0 3.2 40.1 11.7 18.6 5.3 0.3 0.3 2.1 6.1 3.0 2.8 43.0 0.2 3.5 0.5 0.9 4.5 22.1 4.2 12.8 2.0 8.4 3.0 7.4 12.2 1.6 2.1 2.1 1.2 2.5 7.2 1.0 2.1 19.2 2.1 1.5 1.7 4.8 17.9 0.0 4.6 35.7 7.2 16.2 8.7 20.6 0.0 4.0 3.7 41.5 21.7 2.0 0.3 0.3 2.2 18.0 15.5 6.2 METTL11B "C1orf184, HOMT1B" ENSG00000203740 "Methyltransferase like 11B" Q5VVY1 1 170145959-170168866 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "heart muscle: 1.7;skeletal muscle: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "NTERA-2: 1.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028049 Uncertain NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "HPA028049: AB_10610139" "unprognostic (1.12e-1)" "unprognostic (2.57e-1)" "unprognostic (5.62e-2)" "unprognostic (7.59e-2)" "unprognostic (7.25e-2)" "unprognostic (1.19e-1)" "unprognostic (8.68e-2)" "unprognostic (5.24e-2)" "unprognostic (2.76e-3)" "unprognostic (5.43e-2)" "unprognostic (4.56e-1)" "unprognostic (5.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MFSD3 ENSG00000167700 "Major facilitator superfamily domain containing 3" Q96ES6 8 144509070-144511213 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056013 Uncertain Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA056013: AB_2683009" "unprognostic (7.92e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (2.00e-1)" "unprognostic (5.18e-2)" "unprognostic (6.50e-2)" "unprognostic (3.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.06e-1)" "unprognostic (5.49e-2)" "unprognostic (5.29e-2)" "prognostic favorable (5.44e-7)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" 8.4 22.6 9.2 3.4 8.0 1.8 10.7 7.2 12.0 8.0 6.4 22.6 13.5 8.3 4.1 16.1 8.4 2.5 21.8 8.8 6.7 27.5 44.6 7.6 2.8 10.8 7.1 6.7 18.8 12.3 17.8 1.5 9.4 19.2 3.3 1.5 19.6 5.4 23.5 17.8 15.4 1.2 5.4 10.8 15.6 6.3 9.5 2.3 23.9 6.1 1.7 9.7 9.2 7.0 16.2 21.7 5.4 4.6 5.9 4.4 17.6 5.1 5.3 2.8 4.2 7.3 11.2 23.3 17.3 4.8 5.6 15.5 2.5 12.1 0.5 11.0 44.0 7.5 19.9 18.3 11.0 3.6 9.9 6.5 22.3 1.8 7.7 12.1 7.3 16.0 14.2 6.2 6.8 53.7 9.0 18.9 14.3 22.9 36.9 9.9 2.8 41.7 13.2 9.5 39.1 19.7 13.0 31.6 11.3 3.4 33.1 5.2 7.9 3.7 9.9 4.2 7.1 6.0 2.6 8.1 8.0 11.3 6.5 1.8 7.4 3.8 3.9 6.7 3.7 4.9 3.9 4.0 11.0 2.5 3.5 3.6 0.4 3.8 3.6 19.2 4.4 4.1 9.2 8.0 7.2 12.0 8.8 6.7 10.8 7.1 9.4 5.4 9.5 7.0 3.0 3.2 3.7 6.5 8.0 6.0 10.3 17.3 8.6 8.2 18.8 14.5 9.3 30.0 11.8 27.6 10.4 16.5 3.7 31.3 37.2 17.6 0.6 5.1 3.9 3.8 19.8 8.2 6.2 21.0 15.0 4.0 16.3 7.4 0.0 9.7 3.3 27.6 15.5 16.8 6.2 19.6 24.4 7.0 3.2 1.8 4.4 6.4 8.8 1.9 7.5 14.8 6.2 2.5 3.8 15.7 19.1 4.9 14.8 12.8 33.1 63.6 3.2 10.0 0.0 7.0 3.4 3.8 11.7 19.0 7.1 9.3 3.5 16.9 27.1 9.8 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2092.0;Syncytiotrophoblasts: 2371.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 793.9;OE19: 781.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA053311: AB_2682108, HPA077929: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 260.2 163.3 218.0 57.7 224.9 126.2 196.5 245.4 273.1 96.6 214.1 219.6 358.6 91.9 520.6 97.6 112.3 114.4 770.2 232.6 258.0 254.3 166.8 117.5 48.9 239.5 228.8 118.0 90.1 139.1 86.1 173.2 248.3 113.4 217.8 89.9 164.0 114.8 568.0 87.8 301.6 118.8 227.4 54.4 163.0 64.2 230.3 51.9 142.9 578.7 47.7 107.2 90.0 240.5 178.2 128.0 150.0 106.1 533.4 312.1 653.1 158.1 244.2 119.1 205.2 126.8 219.1 10.9 117.1 198.6 117.8 204.7 36.2 155.2 118.5 793.9 94.5 27.1 84.7 60.4 144.9 45.0 58.9 284.2 107.5 178.0 62.3 239.4 202.0 54.2 72.3 65.6 233.6 37.0 48.9 97.4 292.3 781.6 165.8 44.8 63.0 22.2 599.8 159.4 104.1 134.2 148.7 181.1 313.2 308.4 139.1 215.9 174.7 135.8 82.6 92.9 110.8 49.7 37.0 5.8 239.8 109.7 92.3 44.8 172.9 81.2 107.2 150.2 107.9 79.3 130.5 117.3 138.0 78.2 81.4 89.1 32.3 62.3 195.0 58.2 125.5 185.0 218.0 224.9 245.4 273.1 232.6 258.0 239.5 228.8 248.3 227.4 230.3 240.5 915.1 102.5 164.8 48.3 87.6 228.3 251.8 603.8 111.0 144.6 177.0 267.6 670.1 301.7 292.6 557.3 266.9 2092.0 96.5 500.3 1001.8 380.2 18.2 325.6 132.6 268.0 152.8 785.4 75.8 425.9 1327.2 300.3 193.7 257.7 91.8 519.5 257.7 295.0 837.4 131.2 86.4 302.9 374.3 130.0 243.1 46.1 388.0 234.9 519.4 43.1 296.6 257.9 87.6 45.8 90.6 401.8 613.9 399.8 92.9 173.9 1004.1 1227.6 459.9 162.5 506.2 197.5 652.1 23.1 40.4 157.1 232.6 2371.4 123.1 288.6 440.7 237.6 MICOS10 "C1orf151, FLJ36999, Mic10, MINOS1, MIO10, RP5-1056L3.2" ENSG00000173436 "Mitochondrial contact site and cristae organizing system subunit 10" Q5TGZ0 1 19484403-19629821 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 453.9;Cytotrophoblasts: 283.4;Extravillous trophoblasts: 279.7;Hofbauer cells: 531.0;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA059930 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA059930: AB_2684167" "unprognostic (3.84e-2)" "unprognostic (8.74e-3)" "unprognostic (2.66e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.88e-1)" "unprognostic (8.74e-2)" "unprognostic (3.96e-1)" "unprognostic (1.37e-1)" "unprognostic (2.43e-2)" "unprognostic (1.24e-3)" "unprognostic (7.13e-2)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "prognostic favorable (8.11e-4)" 4.9 5.0 11.5 3.1 11.6 2.6 6.0 11.9 13.6 8.6 11.0 9.3 5.1 7.0 6.2 7.2 7.3 4.1 12.6 11.5 13.1 9.7 4.0 4.6 4.3 12.9 11.7 6.4 5.2 11.1 9.5 4.0 13.1 8.5 8.8 5.9 5.1 8.3 14.3 4.8 6.0 7.0 11.3 3.6 6.7 3.4 13.8 4.0 6.5 16.8 5.9 7.0 6.2 11.1 10.0 13.3 7.3 8.4 13.7 13.6 4.5 8.3 9.6 9.5 10.1 9.3 8.7 8.1 6.8 11.0 7.7 6.9 12.8 10.9 15.2 12.7 9.1 7.1 21.2 13.0 6.0 11.6 5.1 10.7 17.5 9.5 11.6 7.4 14.1 6.0 15.8 5.9 14.4 17.2 5.8 15.0 6.2 12.5 16.7 5.7 9.3 10.8 23.3 5.9 15.4 6.7 9.6 7.4 7.1 5.7 7.1 6.7 9.3 7.4 5.7 9.5 8.3 3.8 6.8 8.4 5.8 21.3 7.1 3.8 4.8 5.7 3.6 6.6 3.3 4.3 4.9 4.1 5.1 4.1 6.3 4.5 3.2 2.3 7.0 5.0 4.9 5.9 11.5 11.6 11.9 13.6 11.5 13.1 12.9 11.7 13.1 11.3 13.8 11.1 63.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 453.9 0.0 0.0 0.0 0.0 283.4 25.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 279.7 52.8 0.0 0.0 0.0 0.0 0.0 0.0 531.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 183.5 5.3 0.0 0.0 0.0 MICOS13 "C19orf70, MIC13, P117, QIL1" ENSG00000174917 "Mitochondrial contact site and cristae organizing system subunit 13" Q5XKP0 19 5678421-5680516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 344.8;Cytotrophoblasts: 154.4;Extravillous trophoblasts: 196.7;Hofbauer cells: 242.2;Syncytiotrophoblasts: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042672 Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria Nucleoplasm "HPA042672: AB_10794531" "unprognostic (9.54e-2)" "unprognostic (4.90e-3)" "unprognostic (3.04e-1)" "unprognostic (3.21e-3)" "unprognostic (1.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (2.53e-3)" "unprognostic (2.14e-2)" "unprognostic (9.32e-2)" "unprognostic (2.50e-2)" "unprognostic (1.57e-1)" "prognostic favorable (7.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.94e-2)" "unprognostic (2.27e-1)" "unprognostic (5.47e-2)" 71.0 68.8 139.7 48.4 143.6 54.1 59.3 153.6 180.2 44.4 137.0 76.5 78.6 46.9 44.0 86.9 67.3 53.8 271.2 141.2 154.5 93.5 78.3 44.2 60.4 148.7 143.8 44.7 86.7 97.4 59.8 37.9 147.1 50.1 40.7 18.6 95.3 60.7 279.3 59.7 66.7 43.8 142.0 45.0 61.8 149.2 151.4 38.8 57.9 186.5 35.2 61.3 49.3 146.7 175.7 167.9 43.4 87.6 98.3 117.1 58.7 100.7 121.0 142.6 120.3 132.6 85.2 82.0 157.6 105.2 65.3 124.7 25.8 175.5 34.6 128.9 311.9 76.1 101.2 153.4 162.5 105.8 79.2 133.0 157.9 71.5 92.6 68.0 104.9 112.5 120.5 220.6 101.2 186.3 145.7 129.2 45.1 118.5 474.3 79.5 57.8 286.7 145.3 126.1 111.5 134.8 37.8 198.1 152.2 25.2 128.3 123.8 87.4 121.9 50.5 217.4 169.2 315.8 280.6 66.9 174.5 183.6 126.0 76.8 214.3 77.8 198.9 274.7 237.5 291.6 228.5 225.8 261.4 235.7 222.8 211.3 29.6 192.1 238.8 302.5 211.1 278.1 139.7 143.6 153.6 180.2 141.2 154.5 148.7 143.8 147.1 142.0 151.4 146.7 44.6 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 344.8 0.0 0.0 0.0 0.0 154.4 24.5 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 196.7 46.9 0.0 0.0 0.0 0.0 0.0 0.0 242.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 125.9 5.8 0.0 0.0 0.0 MIEF2 "MGC23130, MiD49, SMCR7" ENSG00000177427 "Mitochondrial elongation factor 2" Q96C03 17 18260597-18266552 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042334 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 62: Horizontal cells - Visual perception" "HPA042334: AB_10794418" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" "unprognostic (7.56e-3)" "unprognostic (1.30e-1)" "unprognostic (8.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-2)" "prognostic favorable (1.75e-7)" "unprognostic (4.68e-2)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (3.06e-2)" 4.8 9.9 3.6 1.5 3.8 1.6 6.0 4.9 4.4 8.8 4.5 6.4 3.6 7.6 4.1 11.4 8.2 2.0 17.1 3.6 3.2 11.9 6.5 5.7 2.3 4.6 3.6 10.2 7.7 6.0 10.5 2.4 3.7 7.8 1.5 2.1 10.6 3.3 24.6 9.6 5.7 1.9 3.0 5.7 6.6 4.9 3.2 1.9 9.8 12.0 1.7 6.2 8.1 3.7 24.0 7.0 2.5 5.5 1.8 2.1 4.4 8.1 4.7 6.6 3.3 9.8 7.4 3.4 8.6 4.0 3.1 17.4 1.8 6.1 3.3 3.3 10.6 1.2 12.0 4.6 3.3 0.6 2.9 2.0 6.3 3.3 2.3 5.4 2.8 4.6 2.9 0.9 2.5 6.8 3.0 2.3 2.1 5.6 3.4 4.2 7.4 4.5 9.2 4.4 1.9 4.3 6.0 7.4 3.4 16.0 18.0 2.1 3.4 4.6 7.5 7.3 3.7 3.6 2.3 1.0 6.6 1.2 2.5 1.6 1.9 6.4 3.5 1.8 3.3 2.1 2.8 2.9 2.0 3.3 3.2 3.4 3.2 7.7 4.7 3.0 3.7 2.1 3.6 3.8 4.9 4.4 3.6 3.2 4.6 3.6 3.7 3.0 3.2 3.7 2.9 16.0 6.0 2.6 4.6 1.9 3.9 6.8 2.8 16.9 5.2 5.5 16.2 1.5 5.6 11.0 16.7 12.0 3.4 6.4 9.8 15.1 14.6 11.4 2.7 4.0 4.2 2.5 2.5 6.0 5.5 4.6 1.5 8.4 2.5 7.0 3.9 3.8 4.1 38.7 3.7 5.4 6.1 2.5 1.1 2.3 8.1 1.6 0.0 1.0 1.9 11.2 6.2 1.5 1.4 21.8 8.6 10.1 3.4 4.2 5.8 5.6 12.5 20.6 6.6 5.2 5.5 2.0 3.8 2.1 1.7 7.7 2.8 10.6 4.6 2.9 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 108.0;Oligodendrocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 64.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 6.3 9.6 3.7 6.2 4.3 5.3 11.1 3.2 5.0 7.5 13.4 12.9 8.8 7.2 12.4 11.5 17.3 7.7 18.4 14.4 4.0 25.4 12.0 7.1 5.1 4.0 5.0 5.4 8.2 14.6 5.4 4.7 4.6 10.9 13.1 6.1 9.7 8.7 13.9 21.4 7.6 7.8 4.0 4.3 8.6 9.8 3.7 6.0 11.1 16.9 7.8 7.7 6.4 4.9 14.6 16.1 7.8 18.4 17.4 23.4 16.6 10.3 16.0 15.1 12.7 21.7 28.1 17.0 10.2 8.4 13.3 35.8 18.1 21.6 18.8 9.9 11.5 7.4 7.0 18.8 14.3 17.5 3.9 11.6 26.4 15.7 13.9 12.7 19.2 12.7 14.5 2.7 24.0 10.8 12.6 9.8 10.8 64.8 16.1 13.8 21.0 14.8 33.7 9.6 18.2 6.1 11.0 17.8 21.8 9.8 18.3 9.7 10.7 9.2 7.6 15.3 11.2 2.6 4.0 9.1 15.9 8.8 11.7 0.0 3.0 1.3 7.4 3.7 9.3 8.7 7.1 6.8 6.5 7.2 6.7 6.7 0.0 10.3 12.0 5.5 5.2 4.0 3.7 4.3 3.2 5.0 14.4 4.0 4.0 5.0 4.6 4.0 3.7 4.9 2.5 16.0 8.6 18.9 5.9 39.9 7.7 13.8 6.2 3.6 6.2 5.8 108.0 11.5 12.6 9.2 6.2 9.8 2.4 8.2 29.4 23.4 8.2 26.0 8.5 5.4 6.0 4.6 43.8 10.6 9.3 8.0 7.1 8.5 2.5 4.2 3.6 5.9 9.7 15.2 47.5 7.1 14.2 3.5 5.0 7.4 6.8 4.3 5.4 12.2 3.4 5.5 5.2 18.1 62.8 8.6 7.0 8.6 4.9 7.5 6.6 25.6 46.3 11.4 0.0 7.3 5.7 9.7 19.0 10.1 42.3 5.1 4.0 8.9 13.6 5.6 MLF1 ENSG00000178053 "Myeloid leukemia factor 1" P58340 3 158571163-158607252 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Differentiation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 182.3;testis: 393.7" "Group enriched" "Detected in many" 10 "Early spermatids: 4964.0;Late spermatids: 12837.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.7" "Lineage enriched" "Detected in single" 9 "T-cells: 8.7" "Cell line enhanced" "Detected in many" "A-431: 84.0" "Low region specificity" "Detected in all" "HPA069479, HPA079339" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA069479: AB_2686140, HPA079339: " "unprognostic (6.49e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.72e-2)" "unprognostic (2.65e-2)" "unprognostic (8.55e-2)" "unprognostic (4.11e-2)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.21e-2)" "unprognostic (1.07e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (5.54e-4)" "unprognostic (9.34e-3)" "unprognostic (2.47e-3)" "unprognostic (3.36e-2)" 10.9 6.8 16.8 3.0 19.8 3.2 17.4 17.3 22.0 9.8 34.5 10.0 1.8 15.9 14.8 10.2 67.9 15.1 138.9 19.1 19.3 21.2 3.6 17.9 2.9 25.1 25.2 12.8 9.6 20.2 18.1 2.7 24.0 6.2 4.7 46.9 5.1 4.6 182.3 6.2 4.0 14.2 22.0 3.5 6.2 393.7 19.4 2.3 16.5 107.2 4.8 14.1 4.2 24.2 84.0 7.7 28.4 0.1 13.8 18.1 7.8 6.8 8.4 31.9 30.5 0.0 44.8 0.0 29.3 13.1 42.8 16.3 0.3 14.2 44.5 0.0 15.3 3.9 6.3 0.9 10.2 0.0 6.4 10.5 22.3 13.8 8.8 28.2 7.3 0.0 6.3 0.1 22.2 12.5 0.0 0.2 7.6 46.4 21.3 0.0 15.4 0.7 25.0 6.4 34.8 21.7 38.1 13.7 43.9 27.7 41.1 8.9 3.8 27.2 27.2 35.4 31.0 15.6 8.2 0.1 20.0 0.1 20.6 0.0 0.0 0.0 2.8 0.0 1.4 0.5 6.9 6.9 0.2 0.3 1.5 3.2 0.3 0.9 0.3 0.1 8.7 2.0 16.8 19.8 17.3 22.0 19.1 19.3 25.1 25.2 24.0 22.0 19.4 24.2 42.0 25.6 28.2 11.8 6.0 44.7 143.4 35.3 27.3 14.9 52.8 68.7 231.2 17.2 55.2 20.2 33.3 0.7 12.0 12.8 72.4 26.9 4964.0 203.9 29.3 28.4 33.9 3.6 20.2 7.6 5.0 56.3 18.8 24.0 43.8 10.0 18.5 0.2 8.0 10.1 14.1 29.3 28.5 4.1 19.7 12837.2 69.9 11.5 23.2 3.7 1.0 28.5 3.1 9.0 12.7 10.2 14.3 50.4 3.4 37.4 1.3 36.6 329.7 71.1 19.7 131.0 40.5 854.2 192.2 10.4 34.2 1.6 25.3 55.9 14.7 83.1 MLPH "exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a" ENSG00000115648 Melanophilin Q9BV36 2 237485428-237555322 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 135.9;salivary gland: 122.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 125.0;Alveolar cells type 2: 389.7;Gastric mucus-secreting cells: 251.8;granulocytes: 187.3;Intestinal goblet cells: 189.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 142.9;MCF7: 255.4;SK-BR-3: 234.5;SK-MEL-30: 182.2;U-87 MG: 236.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA014685 Enhanced NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA014685: AB_1853997" "unprognostic (3.32e-3)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "prognostic favorable (5.14e-6)" "unprognostic (2.26e-4)" "unprognostic (1.36e-2)" "unprognostic (5.44e-2)" "unprognostic (2.66e-1)" "unprognostic (3.74e-3)" "unprognostic (8.16e-2)" "unprognostic (5.73e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.34e-1)" "unprognostic (9.37e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-3)" 13.2 1.4 0.6 2.4 0.7 0.1 56.9 0.7 1.6 69.3 1.3 20.4 8.8 18.1 8.9 6.4 18.0 31.0 69.2 1.1 0.7 4.3 39.0 62.7 0.6 1.1 1.0 11.8 16.1 9.0 2.1 1.9 0.8 135.9 21.7 0.3 122.0 13.0 6.6 11.6 15.2 2.8 0.6 0.2 98.1 2.5 0.8 0.9 39.9 2.5 1.2 22.1 21.9 0.9 0.3 133.7 0.3 0.3 58.5 39.5 0.4 26.8 31.5 14.7 18.5 1.1 101.1 0.2 0.1 49.6 51.0 0.3 0.1 0.9 13.0 0.1 0.3 0.1 0.1 0.0 23.3 0.1 0.7 48.1 14.7 43.4 56.2 75.6 0.1 0.0 0.1 0.3 142.9 255.4 0.4 0.6 0.4 105.4 77.1 0.5 0.1 0.2 0.5 3.2 1.5 0.2 0.1 234.5 182.2 0.7 61.5 1.7 26.8 80.1 2.3 0.9 38.0 0.2 0.2 0.2 236.0 0.1 63.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.7 1.6 1.1 0.7 1.1 1.0 0.8 0.6 0.8 0.9 12.3 125.0 389.7 0.0 0.8 4.1 17.3 6.0 0.0 0.0 95.6 59.7 63.2 52.9 64.2 12.9 0.0 0.4 0.7 34.9 1.9 12.0 0.2 9.5 10.1 10.1 14.4 0.0 0.2 41.3 0.3 4.5 251.8 17.5 187.3 0.2 1.4 28.8 1.2 0.0 0.1 189.0 32.6 0.8 2.9 0.7 8.4 7.4 30.2 5.6 0.6 0.0 0.0 0.0 0.0 58.1 22.4 3.0 0.8 54.4 9.1 0.6 48.5 0.0 0.0 3.1 3.7 0.3 0.6 1.2 2.4 0.7 6.1 0.4 30.5 38.6 MLYCD "hMCD, MCD" ENSG00000103150 "Malonyl-CoA decarboxylase" O95822 16 83899115-83951445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 21.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 97.5;Cone photoreceptor cells: 125.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031625 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA031625: AB_10602028" "unprognostic (6.23e-2)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (6.23e-2)" "unprognostic (1.84e-4)" "unprognostic (2.33e-1)" "prognostic favorable (2.61e-7)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (9.56e-2)" "unprognostic (1.51e-3)" 2.5 2.1 1.9 1.0 2.5 0.4 1.4 1.5 2.4 1.1 2.7 1.7 1.7 1.3 1.2 1.0 1.4 0.7 9.5 1.7 1.9 2.7 5.7 1.2 1.2 2.5 2.5 1.9 5.1 2.0 1.2 0.9 2.0 1.2 1.7 2.4 2.1 1.5 8.2 1.0 1.4 1.2 1.6 1.0 2.5 1.3 3.2 1.0 1.5 21.5 0.9 1.6 0.9 2.5 0.6 1.9 1.6 1.9 2.5 0.9 2.9 0.8 1.2 0.7 0.4 0.9 1.5 0.1 2.4 1.2 2.6 1.5 1.4 0.6 0.7 0.8 1.9 0.9 0.8 1.9 3.0 1.2 2.1 1.1 1.4 0.4 0.4 1.3 0.8 1.4 1.4 0.4 1.1 2.4 0.7 2.7 1.6 2.7 0.4 2.2 1.1 1.1 1.6 1.1 1.4 0.9 3.0 1.1 2.4 2.1 3.4 2.5 0.6 1.8 0.3 1.0 0.2 2.1 1.3 2.0 1.0 0.9 1.9 0.5 0.1 0.5 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.9 2.5 1.5 2.4 1.7 1.9 2.5 2.5 2.0 1.6 3.2 2.5 6.1 6.4 7.3 8.5 10.9 2.0 7.4 1.5 4.6 25.2 7.2 5.2 97.5 17.2 5.5 23.9 125.1 20.2 10.6 12.9 31.3 5.7 4.6 10.4 6.9 8.2 10.2 9.1 3.1 5.5 11.1 10.5 15.3 8.7 5.7 20.1 12.8 46.2 12.3 16.8 6.2 15.2 4.1 10.1 2.0 8.6 14.6 8.2 3.6 3.7 7.7 14.7 27.8 12.5 8.2 6.7 13.1 19.5 6.5 10.4 19.4 19.4 2.4 53.3 6.6 19.0 8.1 12.1 14.4 5.2 2.0 8.2 9.0 17.5 17.1 8.6 MMACHC "cblC, DKFZP564I122" ENSG00000132763 "Metabolism of cobalamin associated C" Q9Y4U1 1 45500300-45513382 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 17.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027394, HPA027399, HPA027402" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA027394: AB_10601669, HPA027399: AB_10601987, HPA027402: AB_2672255" "unprognostic (3.34e-1)" "unprognostic (1.63e-1)" "unprognostic (7.03e-3)" "unprognostic (3.14e-2)" "unprognostic (4.05e-1)" "unprognostic (1.16e-2)" "unprognostic (9.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-2)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.61e-3)" "unprognostic (2.08e-3)" "unprognostic (8.83e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" 2.0 3.1 3.3 1.7 5.3 1.2 3.5 5.1 4.2 2.9 2.3 3.7 3.3 1.7 3.0 2.8 3.5 1.3 6.9 3.4 5.1 3.5 17.4 1.2 1.8 4.1 5.6 3.5 2.9 5.5 1.3 1.5 3.9 2.0 4.4 2.1 5.0 2.4 10.8 2.0 2.4 2.3 3.5 1.6 2.3 4.3 5.6 2.2 2.3 6.6 2.0 1.7 1.5 6.0 7.7 3.9 6.6 10.0 6.1 3.7 8.1 5.9 3.9 10.5 9.4 8.3 4.7 12.0 7.4 4.9 2.0 6.2 12.3 14.0 9.6 3.3 11.4 9.4 6.5 9.2 5.8 13.5 3.3 5.3 7.8 11.6 12.6 3.7 5.1 12.5 10.8 6.7 8.1 8.2 9.1 4.3 10.9 8.8 8.9 11.1 2.7 13.2 6.2 6.0 10.5 5.4 8.8 14.5 19.3 4.9 8.3 4.6 2.3 7.3 9.9 8.3 3.3 9.9 8.5 6.9 5.3 6.4 6.9 2.3 0.5 0.5 0.5 0.8 0.8 0.7 0.7 0.4 0.6 0.6 1.3 0.6 0.9 0.8 2.7 1.3 0.4 0.4 3.3 5.3 5.1 4.2 3.4 5.1 4.1 5.6 3.9 3.5 5.6 6.0 1.1 3.2 5.5 1.6 2.1 0.1 1.8 0.8 5.7 1.3 2.7 1.5 9.8 4.3 2.2 1.8 0.0 3.7 0.6 2.8 5.9 1.3 1.0 3.6 4.8 1.5 4.2 4.8 2.6 1.4 4.3 3.6 7.1 3.2 2.5 2.9 2.5 22.9 3.3 3.3 2.7 3.2 2.0 3.2 0.9 1.2 1.8 2.7 0.0 0.0 0.6 1.4 3.1 1.5 5.3 1.8 2.3 1.5 10.4 1.7 2.0 4.6 1.2 5.2 0.0 5.0 2.4 7.4 2.1 11.5 0.1 2.7 2.4 3.9 5.8 1.8 MOAP1 "MAP-1, PNMA4" ENSG00000165943 "Modulator of apoptosis 1" Q96BY2 14 93182199-93184923 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000939, HPA076948" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 58: Brain - Synaptic function" "Cluster 21: OE19 - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Cell Junctions" "HPA000939: AB_1079402, HPA076948: " "unprognostic (9.40e-3)" "unprognostic (1.26e-1)" "unprognostic (1.57e-1)" "unprognostic (7.52e-2)" "unprognostic (1.21e-1)" "unprognostic (8.75e-2)" "unprognostic (1.01e-1)" "prognostic favorable (7.37e-9)" "unprognostic (1.98e-1)" "unprognostic (6.52e-2)" "unprognostic (1.05e-3)" "unprognostic (1.58e-2)" "prognostic favorable (3.15e-6)" "unprognostic (6.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (9.27e-2)" 17.7 32.2 39.9 11.3 39.8 40.5 19.0 17.8 54.6 25.8 9.4 36.2 13.9 20.9 26.8 17.4 24.0 17.1 55.8 46.4 59.2 30.8 20.3 21.5 19.4 30.1 25.1 19.1 19.3 45.7 37.0 16.2 39.9 32.4 15.9 92.4 20.9 30.6 44.2 17.5 22.2 22.3 22.1 19.2 26.6 10.3 33.7 23.2 24.1 34.6 17.6 24.1 12.3 38.8 9.8 8.2 19.1 25.0 16.3 6.4 11.1 10.2 14.4 12.4 11.5 8.4 8.9 30.4 19.7 14.6 8.5 16.5 13.9 12.7 13.9 10.7 15.8 16.2 17.4 11.5 19.7 15.8 25.0 9.3 18.4 7.6 13.4 30.3 15.9 35.6 6.2 15.6 11.5 40.4 24.1 10.8 7.5 20.8 8.6 12.7 23.3 14.7 29.4 28.7 36.7 31.0 9.1 16.4 48.4 14.8 25.3 12.1 14.6 4.1 5.6 9.9 5.1 30.9 31.3 15.1 12.8 10.2 7.5 53.5 5.9 19.6 15.5 6.9 19.8 6.8 19.1 19.4 6.2 11.9 23.1 21.1 6.1 16.1 8.8 5.4 16.6 12.1 39.9 39.8 17.8 54.6 46.4 59.2 30.1 25.1 39.9 22.1 33.7 38.8 20.4 32.1 32.1 11.8 21.8 16.2 18.2 11.4 13.1 91.8 18.7 12.4 71.9 24.3 13.9 20.2 50.1 28.9 33.7 10.2 41.1 36.2 4.7 26.5 15.3 18.2 48.5 9.9 37.4 15.1 5.7 16.3 12.2 60.6 27.8 36.0 16.8 8.2 16.5 84.1 35.0 21.0 34.6 13.7 9.8 1.7 17.7 15.9 12.4 12.2 16.1 85.4 50.4 18.1 16.3 22.3 7.5 27.4 15.8 21.2 15.7 19.4 7.5 96.0 19.7 15.5 21.8 27.9 22.2 10.5 15.5 47.7 28.2 23.7 16.2 23.9 MOCS2 "MOCO1, MOCS2A, MOCS2B" ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 573.2;Proximal tubular cells: 281.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear speckles" "HPA037679: AB_2675604, HPA037680: AB_10673635" "unprognostic (3.27e-1)" "unprognostic (3.11e-2)" "unprognostic (2.82e-1)" "unprognostic (8.37e-3)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" "prognostic favorable (3.68e-6)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.86e-2)" 48.7 79.4 79.1 24.9 84.9 9.1 42.1 80.3 107.6 34.7 74.4 41.9 40.8 30.0 45.9 35.2 26.5 31.3 87.0 84.3 86.3 114.8 126.2 28.2 26.1 79.2 80.5 43.5 42.4 89.6 30.5 35.9 82.4 36.8 32.3 59.3 48.9 44.9 109.3 16.6 40.2 34.4 85.6 23.6 37.2 26.0 88.0 28.3 55.4 111.8 25.2 30.8 24.6 87.4 79.4 62.7 42.9 109.9 85.0 83.2 51.6 99.5 91.9 74.4 89.8 79.7 56.5 76.7 143.5 69.9 127.1 45.0 91.7 96.7 117.2 19.6 84.8 61.7 58.2 75.9 94.4 65.0 43.0 65.1 41.7 91.7 83.5 81.0 85.1 101.4 58.7 44.2 129.5 115.5 72.7 31.8 37.0 34.2 130.1 36.0 93.0 67.0 144.1 56.6 29.4 33.7 69.4 57.3 72.9 56.9 107.2 15.4 55.6 76.9 81.0 69.1 120.5 49.4 84.8 91.5 106.7 16.8 125.1 14.5 21.8 15.6 36.9 26.9 46.2 37.5 42.7 42.8 29.8 40.5 55.3 49.2 3.8 43.5 25.4 27.8 44.9 28.9 79.1 84.9 80.3 107.6 84.3 86.3 79.2 80.5 82.4 85.6 88.0 87.4 51.7 54.5 29.7 14.4 23.5 13.4 40.1 48.5 19.9 30.2 55.7 50.5 122.9 62.9 37.9 69.9 27.1 95.4 19.4 18.2 573.2 43.7 7.3 22.6 29.0 37.6 26.4 18.7 19.1 43.7 37.3 55.7 19.9 26.8 10.1 38.8 26.0 132.6 41.3 6.7 18.4 22.7 44.7 31.2 20.1 14.6 50.7 28.7 23.2 6.5 12.2 67.5 29.9 4.5 11.9 22.1 18.2 68.8 26.7 34.5 65.7 281.7 32.9 21.7 32.9 73.8 49.4 46.7 62.9 37.5 15.6 32.3 25.8 64.2 30.9 34.5 MOG "BTN6, BTNL11" ENSG00000204655 "Myelin oligodendrocyte glycoprotein" Q16653 6 29657002-29672372 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 73.8" "Cell type enriched" "Detected in some" 49 "Oligodendrocytes: 472.3" "Cancer enriched" "Detected in single" 45 "glioma: 15.1" "Region enriched" "Detected in all" 4 "cerebral cortex: 73.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "white matter: 1396.5" "Low region specificity" "Detected in all" HPA021873 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA021873: AB_1854055" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (7.87e-2)" "unprognostic (3.00e-4)" "unprognostic (4.89e-2)" "unprognostic (4.90e-2)" 0.0 0.0 4.9 0.0 11.0 0.0 0.0 8.6 73.8 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 6.8 8.4 0.1 0.0 0.0 0.0 9.9 8.4 0.1 0.0 0.0 0.3 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 11.0 8.6 73.8 6.8 8.4 9.9 8.4 10.1 8.1 8.4 17.8 0.0 0.0 1.1 0.7 0.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 0.0 0.0 0.3 0.7 0.0 0.0 0.2 0.0 1.0 0.1 0.0 0.0 9.5 472.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.1 0.1 0.0 0.9 0.0 0.3 0.0 0.0 0.3 MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671658-222709930 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "gallbladder: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Breast glandular cells: 7.2;Cholangiocytes: 7.2;Endometrial ciliated cells: 3.9;Exocrine glandular cells: 5.1;Glandular and luminal cells: 4.9;Hepatocytes: 3.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049944, HPA076308" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "Endoplasmic reticulum" "HPA049944: AB_2680964, HPA076308: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" 0.9 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.0 16.8 0.4 0.1 0.1 0.8 3.1 0.4 0.0 0.1 0.6 0.0 0.2 0.6 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.1 0.4 0.6 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.3 0.7 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.9 3.9 0.6 0.1 0.0 0.0 2.5 5.1 0.0 0.1 0.0 4.9 0.0 0.2 0.0 3.2 0.9 0.0 1.9 0.0 0.0 0.3 0.3 0.1 0.0 1.3 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.9 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 739.7;tongue: 559.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 950.0;Distal tubular cells: 1721.8;Proximal tubular cells: 573.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045119: AB_10960421, HPA055790: AB_2682923" "unprognostic (3.30e-2)" "prognostic favorable (1.45e-4)" "unprognostic (5.24e-3)" "unprognostic (1.68e-1)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (7.61e-2)" "prognostic favorable (1.29e-4)" "unprognostic (3.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (5.64e-2)" "prognostic favorable (4.79e-11)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" "unprognostic (7.48e-2)" "unprognostic (8.45e-2)" 61.7 39.6 105.9 33.4 119.5 57.0 52.8 129.7 153.1 52.4 108.0 97.7 84.8 35.7 44.8 71.5 34.7 41.7 739.7 101.2 127.8 259.9 411.2 44.6 44.3 119.2 123.9 43.4 66.0 141.8 38.1 23.7 119.5 43.5 89.9 57.3 87.7 42.3 319.4 40.9 63.8 38.5 117.1 35.0 96.1 22.2 121.5 48.6 82.9 559.2 44.2 47.4 34.9 132.4 25.6 7.5 31.3 107.7 88.4 49.8 45.2 29.1 47.1 45.1 43.9 38.8 17.9 53.6 50.9 45.4 36.1 24.5 47.0 36.7 31.9 36.1 79.0 27.5 35.4 132.6 36.6 104.9 34.1 40.0 51.0 36.8 26.7 13.7 36.9 80.8 94.2 84.1 28.6 40.5 73.1 193.7 16.1 148.0 35.5 39.1 51.7 134.9 85.4 20.5 96.7 85.7 33.6 145.8 34.0 25.9 34.5 154.3 25.3 25.7 26.8 91.6 30.0 55.8 42.2 46.3 23.5 127.0 42.1 60.7 60.0 90.1 41.7 98.3 39.4 33.1 48.5 45.1 72.2 25.4 44.7 43.3 54.6 40.5 128.5 43.0 69.1 49.8 105.9 119.5 129.7 153.1 101.2 127.8 119.2 123.9 119.5 117.1 121.5 132.4 56.1 118.6 48.0 64.6 51.7 45.6 44.2 83.6 29.0 61.1 74.2 79.1 950.0 187.3 67.6 106.7 10.4 22.0 54.2 219.1 1721.8 89.3 66.8 73.7 50.7 51.7 37.2 72.6 49.0 140.3 78.3 74.1 63.7 93.2 71.0 28.0 47.5 391.0 121.4 48.8 74.7 122.1 166.8 89.6 81.7 10.2 66.5 80.3 129.9 20.6 104.7 199.9 58.7 32.2 108.0 65.2 125.0 89.9 114.5 32.0 162.0 573.6 46.3 66.7 92.1 76.9 80.4 163.2 79.6 67.3 55.8 24.4 58.4 39.9 146.7 53.6 MPC2 "BRP44, DKFZP564B167, SLC54A2" ENSG00000143158 "Mitochondrial pyruvate carrier 2" O95563 1 167916675-167937072 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2288.1;Late spermatids: 5134.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056091 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA056091: AB_2683035" "unprognostic (3.25e-1)" "unprognostic (6.82e-2)" "unprognostic (8.79e-3)" "unprognostic (4.15e-2)" "unprognostic (3.47e-1)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (1.53e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-3)" "unprognostic (1.44e-3)" "unprognostic (1.08e-2)" "unprognostic (9.13e-2)" "unprognostic (2.39e-1)" "unprognostic (6.95e-2)" "unprognostic (5.43e-2)" "unprognostic (1.67e-1)" 53.6 89.9 32.3 15.8 37.1 63.3 50.7 34.2 39.0 34.3 35.0 80.3 47.8 30.6 15.8 38.8 34.5 19.6 174.0 36.8 35.6 148.1 266.6 35.1 14.0 31.8 33.4 35.3 52.4 35.6 73.5 13.8 31.6 89.3 33.7 28.4 55.3 16.0 162.1 42.5 65.8 14.8 31.5 28.9 140.4 240.4 34.9 20.1 32.3 66.3 15.0 43.0 35.4 34.4 40.7 43.2 14.6 32.3 31.5 26.2 4.1 70.2 26.9 23.7 27.2 92.3 19.6 75.0 49.4 29.1 21.4 31.4 17.0 28.1 20.3 98.3 34.5 33.2 34.1 60.7 22.4 38.1 21.9 19.6 23.6 41.8 21.8 20.0 20.3 52.5 39.6 34.9 38.7 18.1 52.4 31.4 26.2 73.7 45.2 27.8 31.3 54.7 155.0 30.5 25.8 28.4 41.6 39.1 34.3 29.2 73.9 38.9 30.4 27.8 24.8 45.3 29.9 61.2 65.9 74.5 73.5 28.6 14.6 95.0 33.1 92.5 44.1 30.5 45.7 50.2 51.6 45.8 58.7 41.3 48.6 46.7 61.4 55.6 38.5 40.2 81.3 84.2 32.3 37.1 34.2 39.0 36.8 35.6 31.8 33.4 31.6 31.5 34.9 34.4 81.6 35.3 43.7 14.4 75.0 126.1 157.7 213.8 52.9 54.5 167.2 166.9 428.0 513.3 119.2 130.6 22.9 468.6 78.2 267.5 1025.2 206.1 2288.1 153.3 38.5 75.0 331.5 388.3 23.5 145.5 55.3 119.3 112.1 98.3 88.2 332.1 55.3 679.5 159.6 45.4 19.9 326.4 146.5 77.1 113.3 5134.8 106.2 93.9 120.9 15.9 272.9 123.8 76.2 13.0 16.8 100.5 237.2 112.8 84.7 245.6 516.2 974.3 175.3 69.7 65.7 90.3 147.1 788.0 170.5 75.3 114.4 343.1 94.9 705.0 415.5 173.9 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 MPND FLJ14981 ENSG00000008382 "MPN domain containing" Q8N594 19 4343527-4360086 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 84.7;Paneth cells: 42.7;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043274, HPA045475" Approved Approved "Nucleoplasm,Nucleoli rim" No No "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli rim" Nucleoplasm "HPA043274: AB_2678403, HPA045475: AB_2679339" "unprognostic (3.16e-2)" "prognostic favorable (2.99e-4)" "unprognostic (4.85e-2)" "prognostic favorable (6.12e-4)" "unprognostic (8.60e-2)" "unprognostic (5.37e-3)" "unprognostic (3.16e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.23e-1)" "unprognostic (2.87e-2)" "unprognostic (3.94e-3)" "unprognostic (5.18e-2)" "prognostic favorable (7.04e-4)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (5.44e-2)" "unprognostic (9.04e-2)" 10.5 21.9 22.6 9.3 22.4 15.8 10.7 27.1 35.0 13.2 20.8 25.4 30.6 11.9 8.6 18.1 11.5 9.5 22.4 23.1 20.5 22.7 46.5 12.6 11.7 22.7 20.7 13.0 24.4 15.4 11.0 6.9 23.3 19.0 16.2 4.0 17.2 9.6 23.2 15.6 19.8 6.5 19.4 15.2 20.1 6.6 20.6 10.2 13.3 14.4 7.1 15.2 12.7 25.0 16.0 13.2 21.3 24.6 13.1 6.1 21.7 7.6 7.2 6.2 7.6 25.6 8.1 14.4 23.3 9.9 18.2 16.1 9.8 13.2 3.4 16.4 21.5 11.0 18.4 37.4 10.0 14.9 19.1 9.4 9.4 6.8 7.1 9.3 18.9 37.4 6.0 36.4 7.8 41.8 35.4 12.6 9.8 26.5 18.2 28.8 6.5 21.0 15.5 25.4 23.7 24.3 13.5 19.4 9.9 12.1 13.0 18.1 7.3 9.8 10.4 60.4 15.4 30.1 20.1 9.7 10.9 8.3 11.5 9.3 3.1 1.5 1.3 3.7 2.1 1.0 1.6 1.9 2.9 1.6 1.0 1.1 0.8 1.7 1.8 2.9 3.7 1.3 22.6 22.4 27.1 35.0 23.1 20.5 22.7 20.7 23.3 19.4 20.6 25.0 6.1 0.0 3.7 1.6 5.1 5.4 8.4 1.4 3.4 8.2 9.5 8.5 13.9 11.5 2.7 11.0 2.1 13.6 9.8 84.7 0.0 4.1 0.8 8.0 6.1 6.0 16.7 2.5 2.6 5.1 11.9 5.2 9.2 8.9 4.5 7.8 5.7 23.5 14.8 6.7 2.4 31.2 2.0 26.0 9.6 3.9 6.2 14.4 3.6 1.9 8.8 8.6 21.6 3.5 2.1 4.3 42.7 3.8 7.7 6.9 50.7 15.0 2.3 5.6 6.6 6.1 11.7 0.2 7.6 7.8 8.4 10.4 6.3 9.1 34.6 9.6 MPP2 "DKFZp761D0712, DLG2" ENSG00000108852 "Membrane palmitoylated protein 2" Q14168 17 43875357-43909711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 91.0;Early spermatids: 69.6;Horizontal cells: 35.3;Oligodendrocytes: 59.6;Spermatogonia: 31.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026486, HPA073483" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 56: Bipolar cells - Visual perception" "Mitochondria, Cytosol" "HPA026486: AB_1854085, HPA073483: " "unprognostic (1.18e-1)" "unprognostic (1.68e-1)" "unprognostic (1.30e-5)" "prognostic unfavorable (1.87e-4)" "unprognostic (4.37e-2)" "unprognostic (2.86e-2)" "unprognostic (7.95e-3)" "unprognostic (2.34e-1)" "unprognostic (1.25e-1)" "unprognostic (3.69e-2)" "unprognostic (3.03e-3)" "unprognostic (2.11e-1)" "unprognostic (2.72e-2)" "unprognostic (4.93e-2)" "unprognostic (1.85e-1)" "unprognostic (7.23e-2)" "unprognostic (6.89e-4)" 2.5 3.8 22.2 1.3 25.7 0.5 3.3 25.0 27.0 5.3 7.3 9.4 1.1 5.6 26.0 3.0 5.0 2.2 8.9 23.3 24.2 1.6 0.2 1.4 0.5 30.0 27.1 3.2 3.4 15.8 13.7 2.5 26.5 7.5 1.2 15.7 1.4 8.7 1.0 1.8 2.5 5.0 24.7 0.7 3.7 16.9 28.0 0.7 3.5 1.5 0.6 6.7 4.4 41.6 7.2 10.5 11.0 15.7 1.4 1.0 6.0 2.5 0.3 9.9 9.0 3.7 4.7 10.4 5.7 2.5 12.2 2.9 15.1 6.0 7.0 0.0 11.5 0.9 9.2 0.2 0.3 0.0 2.9 1.5 0.5 6.8 0.1 5.4 0.7 16.6 3.9 0.0 2.5 2.8 1.5 0.8 19.7 0.8 6.4 7.4 15.5 0.7 0.2 0.2 11.6 10.7 3.0 1.0 4.1 9.8 24.5 4.9 0.1 10.5 13.2 4.0 4.5 3.4 7.4 0.0 15.8 6.9 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 22.2 25.7 25.0 27.0 23.3 24.2 30.0 27.1 26.5 24.7 28.0 41.6 2.1 0.0 0.0 11.1 0.0 0.4 1.4 1.0 0.0 91.0 0.5 2.9 10.5 0.0 0.0 0.0 2.1 5.8 0.1 0.1 0.0 0.7 69.6 0.1 0.4 1.4 0.0 0.0 20.4 0.4 0.4 2.7 0.0 0.1 0.0 1.2 0.0 0.0 0.7 35.3 19.0 0.0 0.0 0.0 0.4 21.1 3.7 0.2 0.0 1.9 0.0 16.1 0.0 13.6 59.6 0.5 0.0 5.7 0.1 0.0 0.0 0.1 0.0 7.1 0.0 1.5 1.9 23.2 31.4 0.2 0.1 2.7 0.3 0.1 0.0 0.0 MRO "B29, C18orf3, FLJ30140" ENSG00000134042 Maestro Q9BYG7 18 50795120-50825402 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 44.7;kidney: 24.1;testis: 28.9" "Cell type enhanced" "Detected in some" "Astrocytes: 30.0;Granulosa cells: 11.3;Hepatic stellate cells: 37.5;Kupffer cells: 13.0;Proximal enterocytes: 20.0;Proximal tubular cells: 16.0" "Cancer enriched" "Detected in some" 7 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 2.4;ASC TERT1: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022011 Approved NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022011: AB_2670880" "unprognostic (9.21e-5)" "unprognostic (5.22e-2)" "unprognostic (7.87e-3)" "unprognostic (1.45e-2)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-2)" "unprognostic (5.11e-2)" "unprognostic (3.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (4.71e-1)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (3.99e-3)" "unprognostic (6.06e-4)" 2.3 2.5 36.6 0.5 42.7 0.2 0.6 32.5 33.1 0.3 18.4 0.2 8.0 0.2 3.1 0.5 0.3 1.0 3.0 33.3 44.7 24.1 7.2 0.2 0.3 35.9 38.5 3.3 1.8 5.3 1.3 0.7 34.4 0.2 0.2 1.6 0.3 2.2 2.0 0.1 4.7 0.3 33.8 2.2 1.3 28.9 40.8 1.2 6.0 1.3 0.1 0.4 0.2 31.0 0.0 0.0 0.0 0.2 2.4 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.3 0.1 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 36.6 42.7 32.5 33.1 33.3 44.7 35.9 38.5 34.4 33.8 40.8 31.0 0.2 0.0 0.0 30.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.8 1.5 0.0 0.0 2.1 0.0 0.0 0.2 5.9 0.0 0.8 0.2 0.0 0.9 0.0 0.0 1.5 1.0 0.8 0.8 1.1 0.1 0.0 11.3 37.5 4.7 8.4 0.0 1.1 0.1 0.0 13.0 0.3 3.3 1.2 1.8 0.0 3.7 0.0 3.9 1.0 5.0 0.3 0.1 0.0 0.7 0.0 0.1 20.0 16.0 0.0 0.2 0.0 0.4 0.1 1.2 0.5 0.0 0.0 0.1 0.1 4.3 0.6 0.1 MROH7 "C1orf175, FLJ46354, HEATR8" ENSG00000184313 "Maestro heat like repeat family member 7" Q68CQ1 1 54641754-54710266 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 55.5" "Group enriched" "Detected in some" 57 "Early spermatids: 179.0;Late spermatids: 546.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA071840 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA071840: AB_2732187" "unprognostic (1.52e-3)" "unprognostic (1.51e-3)" "unprognostic (1.65e-2)" "unprognostic (2.77e-4)" "unprognostic (1.81e-1)" "unprognostic (9.88e-4)" "unprognostic (1.09e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (4.16e-2)" "unprognostic (1.79e-2)" "unprognostic (7.93e-2)" "unprognostic (7.40e-3)" "unprognostic (2.38e-1)" "unprognostic (5.83e-2)" "unprognostic (4.15e-2)" 0.2 0.6 2.2 0.0 2.5 0.7 0.2 2.9 2.8 0.7 7.0 3.1 0.1 1.1 1.0 0.6 1.3 0.2 2.7 2.3 2.4 2.3 1.1 0.4 0.1 2.9 3.1 2.9 0.3 0.5 4.3 0.0 2.6 2.3 0.3 0.5 1.8 0.7 0.7 1.0 1.4 0.1 2.5 0.2 1.7 55.5 3.2 0.0 5.3 0.2 0.0 1.8 0.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 2.9 2.8 2.3 2.4 2.9 3.1 2.6 2.5 3.2 2.5 0.0 0.0 1.3 0.0 0.2 0.9 0.9 0.1 0.0 1.7 0.3 0.5 4.0 0.0 1.4 0.0 0.0 0.0 0.0 4.0 0.0 0.1 179.0 1.1 0.2 0.3 2.4 0.0 0.0 0.4 0.0 0.2 0.0 1.2 5.1 0.3 0.4 0.3 0.4 0.0 0.0 3.0 0.0 1.0 0.7 546.1 4.4 0.5 0.0 0.0 0.7 2.5 0.0 0.0 0.0 0.1 6.1 4.5 0.0 0.3 5.0 0.2 1.0 0.4 0.0 1.9 0.2 6.3 2.8 0.0 0.4 0.1 0.2 0.5 2.2 1.1 MROH8 "C20orf131, C20orf132, dJ621N11.3, dJ621N11.4" ENSG00000101353 "Maestro heat like repeat family member 8" 20 37101226-37179588 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 9.8" "Cell type enhanced" "Detected in many" "Adipocytes: 25.4;Breast myoepithelial cells: 33.9;Early spermatids: 33.9;Late spermatids: 31.4;Spermatocytes: 23.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.5" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.16e-2)" "unprognostic (6.65e-3)" "unprognostic (5.88e-3)" "unprognostic (1.04e-2)" "unprognostic (2.17e-2)" "unprognostic (6.92e-2)" "unprognostic (3.31e-3)" "unprognostic (2.50e-4)" "unprognostic (1.98e-1)" "unprognostic (3.00e-2)" "unprognostic (1.11e-3)" "unprognostic (9.70e-3)" "unprognostic (5.00e-9)" "unprognostic (1.39e-1)" "unprognostic (1.01e-1)" "unprognostic (3.10e-2)" "unprognostic (1.62e-1)" 0.8 0.6 2.0 0.3 2.3 1.4 0.8 3.1 3.1 0.7 2.8 1.0 0.2 1.0 4.0 0.5 1.0 0.6 1.3 2.2 2.3 0.8 1.4 0.4 0.5 1.9 2.0 0.9 0.8 0.4 2.6 0.4 2.1 1.0 0.5 3.9 1.1 0.9 2.5 1.8 0.6 0.9 1.7 0.8 0.5 9.8 2.3 0.7 0.7 2.5 0.9 0.6 0.5 2.4 0.6 0.0 0.9 0.3 1.3 0.6 0.6 0.3 0.2 0.3 0.3 1.3 0.7 1.0 0.2 0.0 0.7 0.6 0.5 0.0 0.5 0.0 0.0 0.7 1.3 0.3 0.4 0.2 0.6 0.3 0.1 0.3 0.0 0.8 0.9 0.7 0.6 0.6 0.0 0.0 0.5 1.6 0.3 0.0 0.3 0.7 0.0 0.2 0.5 0.7 0.5 0.5 0.5 0.0 0.4 0.7 0.0 0.1 1.7 1.0 0.3 0.2 0.1 0.9 0.2 1.0 0.9 0.1 0.9 1.3 0.9 0.5 0.3 0.7 0.2 0.7 0.3 0.4 0.3 0.6 0.2 0.2 4.5 0.1 0.6 1.1 0.2 0.3 2.0 2.3 3.1 3.1 2.2 2.3 1.9 2.0 2.1 1.7 2.3 2.4 25.4 3.2 0.6 17.3 2.0 0.6 1.1 0.5 1.8 6.2 6.6 33.9 3.0 7.2 0.2 0.0 8.4 3.7 0.7 1.6 0.0 0.3 33.9 2.2 6.5 4.0 1.2 3.2 15.0 0.2 1.1 5.3 6.1 2.6 0.0 11.9 1.8 3.9 2.7 0.0 17.5 1.2 0.0 1.6 1.1 31.4 1.5 3.2 1.8 3.7 1.0 5.8 1.0 7.1 8.5 0.1 1.4 3.0 3.5 0.6 4.0 2.6 1.5 4.9 0.0 1.1 11.7 23.6 5.9 1.5 0.4 1.4 1.5 3.4 1.3 0.4 MRPL10 "L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8" ENSG00000159111 "Mitochondrial ribosomal protein L10" Q7Z7H8 17 47823272-47831541 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021234, HPA029885" Enhanced Enhanced Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA021234: AB_1854098, HPA029885: AB_2673233" "unprognostic (6.84e-3)" "unprognostic (1.03e-1)" "unprognostic (8.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.97e-1)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.21e-2)" "unprognostic (1.03e-1)" "unprognostic (8.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.16e-2)" "unprognostic (1.29e-1)" "unprognostic (2.82e-1)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.87e-2)" 32.1 32.8 35.6 14.4 36.6 24.7 29.7 36.9 39.7 30.1 33.2 40.9 25.6 31.4 22.8 27.1 29.8 21.9 58.1 34.9 36.7 31.2 29.9 20.1 26.2 36.5 36.0 48.8 41.0 28.9 17.3 23.2 36.2 24.8 23.1 21.7 22.1 25.5 64.2 23.8 26.7 26.5 35.7 28.2 36.2 20.1 37.4 25.9 23.1 52.4 26.9 37.9 25.4 36.8 36.8 80.0 33.4 33.0 78.3 71.3 61.6 32.2 54.0 54.2 46.4 155.7 49.2 59.1 71.9 42.0 36.0 33.6 48.3 62.6 48.0 57.6 76.4 47.2 41.7 110.0 67.4 42.8 25.5 80.8 53.2 64.4 90.7 63.7 52.9 58.4 64.8 56.6 42.3 73.3 43.2 55.0 55.1 64.0 76.5 34.7 63.7 66.5 59.9 35.8 39.2 63.2 23.9 26.9 68.7 62.9 81.2 45.5 32.3 47.5 39.0 32.3 45.1 100.1 82.4 48.0 41.4 32.3 32.4 29.8 37.3 18.5 61.6 39.6 59.1 31.8 42.4 55.3 43.0 36.6 35.6 42.2 14.5 26.6 32.9 26.0 52.5 42.0 35.6 36.6 36.9 39.7 34.9 36.7 36.5 36.0 36.2 35.7 37.4 36.8 17.1 6.4 13.6 4.2 19.2 12.5 20.8 42.5 27.9 15.3 25.3 31.5 31.5 20.0 19.5 14.7 6.2 90.5 50.9 17.9 46.9 43.8 22.0 7.9 16.3 21.7 8.5 30.3 5.4 54.7 60.0 23.3 20.4 11.0 8.8 31.8 20.7 15.6 41.7 32.0 6.6 20.7 32.6 31.4 10.8 30.5 24.5 17.3 16.0 2.8 31.8 24.4 44.3 7.1 8.2 40.4 14.7 24.0 22.8 18.4 30.8 47.5 6.1 13.7 6.6 17.5 28.0 23.2 29.2 24.1 12.5 77.3 48.5 49.4 31.9 18.8 MRPL12 "MRPL7, MRPL7/L12, RPML12" ENSG00000262814 "Mitochondrial ribosomal protein L12" P52815 17 81703367-81707517 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 303.2;Undifferentiated cells: 364.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022853, HPA023043" Supported Supported Mitochondria NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA022853: AB_1854099, HPA023043: AB_1854100" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (6.59e-2)" "unprognostic (1.66e-2)" "unprognostic (9.52e-2)" "unprognostic (5.97e-2)" "unprognostic (5.97e-3)" "prognostic unfavorable (2.35e-4)" "unprognostic (1.78e-1)" "unprognostic (6.47e-3)" "unprognostic (8.17e-2)" "unprognostic (3.07e-1)" "unprognostic (8.77e-3)" "unprognostic (3.41e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (9.26e-2)" 57.8 73.7 39.4 28.4 39.9 31.0 44.0 46.8 51.9 34.4 50.4 79.7 47.3 39.1 11.0 96.8 35.1 10.9 209.9 39.0 42.2 86.9 184.9 34.9 25.5 40.7 43.1 26.7 60.6 45.9 39.1 19.5 41.0 44.9 37.3 7.3 48.1 21.5 169.7 51.1 51.3 20.6 38.8 53.8 57.9 32.3 46.2 20.1 34.0 148.1 27.7 45.4 46.5 39.4 153.6 256.8 67.5 78.2 50.2 55.0 124.3 117.0 71.3 173.2 128.3 216.5 71.6 236.5 69.2 77.5 116.7 127.1 87.6 150.7 87.6 55.9 438.3 181.1 140.2 246.5 74.0 200.5 90.9 63.4 108.5 119.4 132.4 55.4 146.1 115.6 179.4 75.6 87.1 194.2 171.6 295.9 106.0 165.9 330.6 160.7 109.5 176.4 129.8 126.1 171.4 220.7 86.1 366.1 199.8 69.1 186.2 180.5 76.7 131.0 155.8 103.4 241.2 146.2 54.3 137.0 89.3 143.0 100.6 17.7 63.1 9.0 37.9 84.8 52.6 66.2 37.8 42.6 93.7 62.1 39.2 36.0 6.9 43.5 49.8 77.0 35.8 48.9 39.4 39.9 46.8 51.9 39.0 42.2 40.7 43.1 41.0 38.8 46.2 39.4 43.0 19.2 12.8 4.9 42.2 53.3 83.7 101.7 8.6 17.1 67.2 85.0 88.7 84.4 47.6 46.0 4.2 172.4 29.1 303.2 219.2 113.0 38.9 40.6 39.8 47.8 104.0 40.4 4.5 118.5 187.2 38.9 28.5 33.6 30.5 75.7 39.7 223.4 167.0 23.5 6.0 257.7 44.7 62.2 34.5 127.2 39.4 36.8 58.7 1.9 59.7 29.7 45.3 3.0 4.6 126.5 126.9 32.7 24.4 137.1 196.2 258.5 35.0 17.3 32.9 30.8 65.1 46.5 56.9 30.1 60.5 112.5 25.2 126.0 364.0 109.8 MRPL16 "FLJ20484, PNAS-111" ENSG00000166902 "Mitochondrial ribosomal protein L16" Q9NX20 11 59806140-59810778 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054133 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA054133: AB_2682394" "prognostic favorable (1.04e-4)" "unprognostic (1.13e-1)" "unprognostic (3.45e-3)" "unprognostic (5.88e-2)" "unprognostic (2.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.20e-1)" "unprognostic (2.40e-3)" "unprognostic (1.50e-3)" "unprognostic (2.67e-2)" "unprognostic (2.87e-3)" "unprognostic (3.01e-2)" "unprognostic (1.23e-1)" "unprognostic (6.38e-2)" "unprognostic (2.01e-2)" 35.2 61.4 44.1 29.6 44.7 57.0 34.6 45.6 54.7 30.4 45.4 49.7 42.1 32.7 23.1 33.7 29.0 20.6 85.7 44.2 45.3 51.2 78.3 25.6 44.3 43.4 44.0 31.5 38.6 56.1 23.0 29.8 43.8 25.3 48.3 21.4 43.2 28.8 85.8 24.6 34.7 36.3 44.5 41.6 44.3 34.1 45.3 50.7 20.7 103.5 46.0 29.4 25.7 44.8 76.3 75.4 53.4 50.1 74.9 59.1 48.0 52.1 68.9 93.9 80.1 75.1 79.5 174.0 87.0 68.2 50.3 72.8 178.0 96.9 84.0 58.9 89.5 92.7 69.9 89.5 57.8 139.4 55.1 71.1 52.4 78.8 56.4 54.5 92.4 112.6 278.4 51.2 70.9 150.6 97.8 224.1 84.1 89.8 124.2 85.4 78.6 91.1 137.2 103.3 50.2 34.9 83.4 83.8 134.3 49.4 100.1 132.0 46.3 36.9 50.7 77.4 63.7 57.9 69.8 240.7 44.9 88.1 40.8 80.8 95.1 72.9 87.4 118.1 91.0 118.7 96.5 91.5 116.1 121.2 102.8 91.4 18.1 116.8 94.5 166.9 108.2 149.7 44.1 44.7 45.6 54.7 44.2 45.3 43.4 44.0 43.8 44.5 45.3 44.8 44.3 48.1 31.4 10.4 43.6 31.9 19.7 87.9 34.1 9.9 29.4 47.0 146.1 31.5 42.6 42.3 12.5 94.2 45.9 35.5 248.4 47.9 18.0 28.5 41.5 41.0 34.1 64.8 9.0 53.4 74.1 46.7 46.9 28.5 61.4 104.6 35.7 73.6 75.3 8.4 10.9 67.7 46.8 45.6 24.4 11.8 39.7 34.5 44.4 10.3 54.4 45.4 42.2 9.5 8.0 43.0 42.2 37.6 66.0 19.4 65.6 125.2 44.0 17.0 72.3 34.1 53.1 54.8 46.5 64.4 36.8 28.5 34.9 120.3 82.2 22.3 MRPL2 "CGI-22, MRP-L14, RPML14" ENSG00000112651 "Mitochondrial ribosomal protein L2" Q5T653 6 43054029-43059438 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007455, HPA064814" Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA007455: AB_1079410, HPA064814: AB_2685358" "unprognostic (2.31e-1)" "unprognostic (1.49e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.17e-1)" "prognostic favorable (6.01e-4)" "unprognostic (3.07e-1)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "unprognostic (6.42e-2)" "unprognostic (2.33e-2)" "unprognostic (3.13e-1)" "unprognostic (2.78e-1)" 26.5 32.4 27.9 12.6 28.8 20.0 26.0 31.0 37.6 23.2 27.9 27.5 25.6 23.5 13.7 24.6 22.2 10.1 48.2 28.3 31.7 33.7 51.2 18.6 13.4 29.8 28.9 24.5 27.1 29.6 29.5 13.3 30.1 22.0 16.8 10.9 22.6 17.6 75.1 25.1 20.3 12.0 27.4 19.9 23.6 19.7 29.0 17.7 26.7 56.7 14.4 22.6 21.4 28.9 47.9 43.1 20.3 39.3 28.4 20.7 38.9 20.4 24.8 47.3 41.3 109.0 15.4 61.8 42.3 24.6 36.2 49.9 50.5 48.7 27.8 30.4 90.9 46.8 34.9 109.5 57.2 43.5 21.0 27.6 51.4 52.5 82.8 22.6 32.6 68.7 84.6 36.6 23.6 84.0 48.1 127.1 22.7 175.7 49.5 59.0 25.1 77.3 38.2 26.3 51.3 27.4 18.2 39.4 73.4 18.6 41.4 73.9 27.3 27.6 40.0 35.7 58.7 47.7 44.9 115.2 21.5 65.2 27.8 17.5 37.8 30.2 28.4 40.9 36.5 46.5 31.8 33.6 54.3 48.6 32.7 32.3 9.8 38.5 33.7 56.1 39.2 31.3 27.9 28.8 31.0 37.6 28.3 31.7 29.8 28.9 30.1 27.4 29.0 28.9 36.8 22.4 18.6 5.5 27.5 24.3 32.0 86.5 19.4 22.7 25.9 30.0 37.5 38.6 48.9 60.7 27.1 74.0 21.3 43.1 185.9 59.1 94.0 30.6 34.1 32.1 30.6 35.3 5.3 53.7 53.1 31.1 30.1 32.5 28.5 43.1 33.2 75.9 49.3 5.0 5.8 44.2 69.2 23.7 26.6 37.0 55.0 22.9 53.4 2.8 41.3 44.7 43.3 2.0 5.5 44.2 51.3 51.6 35.6 31.6 77.6 159.4 40.4 23.4 26.3 32.5 82.7 53.1 41.7 35.7 27.1 63.5 27.2 59.0 65.7 28.7 MRPL34 "L34mt, MGC24974, MGC2633" ENSG00000130312 "Mitochondrial ribosomal protein L34" Q9BQ48 19 17292609-17306843 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 403.0;Proximal tubular cells: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049276 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA049276: AB_2680697" "unprognostic (1.21e-2)" "unprognostic (3.22e-2)" "unprognostic (4.85e-2)" "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (4.27e-2)" "unprognostic (1.46e-1)" "unprognostic (4.93e-2)" "unprognostic (1.29e-1)" "unprognostic (5.45e-2)" "prognostic favorable (4.87e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.29e-6)" "unprognostic (2.44e-1)" "unprognostic (2.42e-1)" "unprognostic (1.23e-1)" "unprognostic (2.18e-2)" 69.6 115.4 64.0 27.5 67.0 26.2 64.7 69.2 72.2 51.4 96.7 99.7 71.5 58.7 23.5 62.8 45.6 17.6 178.2 63.4 69.5 126.0 195.0 47.1 28.6 64.3 64.1 40.9 69.5 91.8 74.1 20.3 64.6 55.3 29.8 31.6 65.3 40.2 210.5 60.6 75.8 18.3 64.1 55.8 87.7 93.6 70.7 38.0 61.5 139.6 21.8 64.0 50.6 66.0 91.9 55.3 35.4 45.4 88.2 48.7 132.1 45.4 47.7 36.6 44.8 53.6 64.2 115.2 126.7 25.2 50.7 73.6 57.1 53.5 25.9 171.3 198.5 81.4 87.2 119.2 78.7 89.2 103.9 56.6 71.2 38.0 52.1 38.9 57.8 95.5 119.6 136.4 35.7 86.7 113.4 187.4 97.6 147.2 293.8 97.9 52.0 160.9 107.9 68.6 84.1 136.7 42.6 67.2 105.9 37.0 58.7 74.3 49.0 52.7 32.8 151.6 87.4 186.5 305.3 129.0 65.4 161.7 49.1 169.6 162.3 159.5 172.4 177.0 192.5 204.0 203.5 177.3 178.1 211.0 197.5 172.2 52.3 141.7 107.0 233.6 210.8 276.7 64.0 67.0 69.2 72.2 63.4 69.5 64.3 64.1 64.6 64.1 70.7 66.0 64.4 35.3 41.4 13.7 51.7 60.7 33.0 128.5 74.0 50.2 81.7 108.2 153.4 91.5 64.6 82.8 20.9 118.5 94.1 138.9 403.0 88.5 57.6 48.1 46.7 54.2 68.3 45.5 16.1 68.8 112.1 55.6 60.1 45.4 39.3 37.1 59.6 290.3 172.4 42.1 16.7 125.4 134.3 70.1 55.9 31.9 82.0 61.4 81.8 6.5 90.0 45.0 97.9 6.0 12.8 64.7 99.1 91.7 80.3 45.7 219.5 414.8 42.3 49.7 72.3 48.1 69.7 233.1 14.9 93.2 72.0 78.3 62.0 109.5 130.6 36.7 MRPL35 ENSG00000132313 "Mitochondrial ribosomal protein L35" Q9NZE8 2 86199355-86213790 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043482 Uncertain "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043482: AB_10959449" "unprognostic (3.68e-2)" "unprognostic (6.24e-2)" "unprognostic (9.14e-3)" "unprognostic (1.68e-2)" "unprognostic (9.38e-3)" "unprognostic (7.72e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.81e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" "unprognostic (1.66e-1)" "prognostic favorable (9.96e-6)" "unprognostic (1.94e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (2.52e-3)" 25.0 29.7 19.6 24.7 22.0 20.5 25.3 21.2 26.1 18.9 18.8 55.5 57.9 17.8 13.6 31.2 21.9 19.9 83.8 20.1 21.9 47.5 46.1 15.5 35.6 19.7 19.6 17.3 19.7 45.9 12.0 20.9 20.9 19.1 58.7 23.2 24.3 25.1 69.4 14.3 43.3 30.1 20.5 21.6 32.2 16.2 21.7 29.1 19.9 113.5 40.0 32.2 18.0 21.2 83.4 35.8 53.6 55.0 55.1 51.6 77.2 71.5 51.5 88.0 64.9 31.4 69.1 154.1 79.0 61.6 70.9 71.2 109.3 64.2 98.1 89.0 51.0 88.5 25.9 80.5 44.7 143.0 68.0 38.6 75.0 95.4 46.4 42.3 81.4 82.6 111.4 66.1 82.0 50.2 82.0 97.3 56.2 107.0 46.4 71.4 143.1 129.8 90.6 60.2 45.2 43.7 66.1 106.8 116.8 37.5 43.7 57.0 62.2 70.4 85.9 89.8 112.6 49.9 157.4 170.0 61.7 150.1 65.6 30.4 36.0 19.0 21.4 48.4 24.0 45.2 31.9 28.0 41.9 41.4 37.4 29.7 5.1 23.5 50.8 42.2 40.4 32.4 19.6 22.0 21.2 26.1 20.1 21.9 19.7 19.6 20.9 20.5 21.7 21.2 17.3 22.4 15.0 7.2 17.5 7.1 20.3 67.4 11.4 21.9 17.0 20.1 135.9 18.6 42.2 18.4 31.3 49.2 15.0 46.7 97.8 42.0 3.7 22.0 28.3 19.2 26.5 35.1 11.6 43.0 49.7 19.8 23.4 22.1 21.0 21.9 15.7 52.9 65.3 23.5 12.7 31.4 48.8 23.8 6.1 5.0 12.8 23.7 10.6 12.2 32.1 21.5 19.6 5.0 11.5 41.8 29.5 17.7 29.5 17.3 52.6 82.8 24.9 25.4 26.3 17.2 47.2 14.6 26.3 29.0 8.5 27.0 14.6 38.1 56.3 25.2 MRPL40 "MRP-L22, NLVCF" ENSG00000185608 "Mitochondrial ribosomal protein L40" Q9NQ50 22 19432545-19436075 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006181 Uncertain Supported Nucleoli,Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "HPA006181: AB_1079411" "unprognostic (4.12e-2)" "prognostic favorable (7.57e-4)" "unprognostic (2.64e-2)" "unprognostic (1.29e-1)" "unprognostic (5.76e-2)" "unprognostic (4.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" "unprognostic (4.08e-2)" "unprognostic (1.19e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (2.67e-2)" "unprognostic (1.75e-1)" "unprognostic (8.07e-2)" "unprognostic (2.29e-1)" "unprognostic (3.14e-2)" 39.4 54.4 59.9 26.1 61.6 28.3 47.6 63.9 79.7 50.0 60.3 33.6 26.1 31.3 77.4 35.6 54.8 31.5 100.7 59.0 62.3 69.1 118.8 28.9 35.5 62.5 60.6 44.5 57.1 85.0 11.2 30.7 62.5 46.4 35.9 35.0 72.1 43.0 135.8 29.2 24.7 32.6 63.6 27.1 33.8 31.4 61.7 29.7 79.0 142.0 40.9 36.4 7.0 65.0 84.8 83.8 26.9 64.0 111.5 98.8 45.4 62.1 95.6 116.9 133.6 105.5 49.0 73.2 71.0 93.7 67.8 82.9 118.8 141.2 122.6 69.8 129.7 72.8 76.0 184.4 158.1 117.7 46.1 102.3 123.6 101.1 179.8 77.3 95.6 35.0 265.8 91.2 127.5 106.9 44.9 77.6 22.7 190.2 100.3 49.7 110.6 44.2 135.9 67.9 45.6 48.3 100.7 94.0 159.7 60.2 80.2 52.9 60.6 118.6 127.3 41.6 64.0 78.1 115.7 147.6 79.2 71.6 99.5 45.1 88.3 76.6 71.7 108.9 82.7 162.7 72.4 74.6 100.1 155.6 85.9 75.6 10.4 90.5 90.2 106.5 91.9 103.5 59.9 61.6 63.9 79.7 59.0 62.3 62.5 60.6 62.5 63.6 61.7 65.0 43.3 44.8 35.3 8.8 53.8 40.4 73.3 181.9 52.3 31.0 59.4 85.9 86.1 71.4 106.6 47.8 12.5 129.6 42.9 35.2 260.3 83.8 114.9 104.4 61.9 40.3 34.9 27.1 3.6 97.9 128.9 55.9 32.1 46.1 33.7 44.2 40.0 146.3 135.6 21.9 5.8 47.8 91.6 43.6 40.0 152.4 72.4 42.9 85.4 4.7 73.9 120.4 37.0 3.5 12.0 73.9 48.6 72.2 92.6 53.6 89.8 254.9 163.5 50.3 46.0 53.9 74.3 82.9 72.1 64.8 38.5 62.9 35.1 103.8 49.3 52.2 MRPL41 "BMRP, MRP-L27, MRPL27, PIG3, RPML27" ENSG00000182154 "Mitochondrial ribosomal protein L41" Q8IXM3 9 137551879-137552555 "Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 340.5;skeletal muscle: 407.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 909.5;Distal tubular cells: 972.4;Hepatocytes: 856.2;Late spermatids: 839.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 503.2;PC-3: 471.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024550, HPA027160" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA024550: AB_1854112, HPA027160: AB_1854113" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (6.92e-2)" "unprognostic (1.22e-3)" "unprognostic (5.86e-3)" "unprognostic (8.04e-2)" "unprognostic (2.05e-1)" "unprognostic (1.60e-1)" "unprognostic (1.47e-1)" "unprognostic (1.14e-1)" "unprognostic (4.83e-3)" "unprognostic (3.24e-2)" "unprognostic (2.06e-3)" "unprognostic (3.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" 83.7 74.7 222.0 22.9 206.1 26.1 57.4 203.8 340.5 53.9 169.2 66.4 45.4 45.9 8.4 42.4 46.6 14.8 325.4 210.3 190.6 79.8 157.8 42.1 24.6 209.0 190.7 61.1 44.8 42.2 55.1 12.2 187.9 113.0 17.4 9.9 69.6 26.2 407.5 58.6 56.8 12.2 183.4 54.2 79.1 40.3 227.1 16.1 44.9 129.4 13.1 59.4 45.4 188.9 93.7 165.9 25.5 61.9 40.7 35.5 122.1 112.8 33.1 59.1 47.4 122.6 49.6 71.0 148.4 31.5 78.0 186.5 37.4 60.0 6.4 97.9 208.6 62.0 91.9 193.6 92.8 101.1 211.4 67.3 85.4 51.5 18.2 23.4 55.4 58.7 147.8 26.8 32.6 503.2 33.7 337.6 94.6 118.0 471.6 40.1 44.0 95.9 50.5 67.7 85.7 88.6 78.0 138.6 194.5 15.2 124.0 91.5 95.4 93.1 121.3 162.9 153.4 78.4 146.2 133.7 101.8 104.4 70.9 425.2 305.5 251.8 225.6 272.9 211.5 313.8 235.0 257.0 260.3 249.7 221.0 206.2 38.3 180.8 254.2 422.6 332.2 350.3 222.0 206.1 203.8 340.5 210.3 190.6 209.0 190.7 187.9 183.4 227.1 188.9 99.0 28.9 33.6 59.7 90.7 140.1 138.3 239.3 121.3 52.4 193.9 221.5 909.5 178.7 121.1 263.0 10.4 115.9 89.7 670.5 972.4 157.8 299.6 165.2 136.0 103.1 268.5 66.0 30.6 192.1 147.7 127.1 192.7 136.7 54.0 85.4 102.1 856.2 244.8 28.6 47.7 332.9 229.9 122.7 115.4 839.0 121.8 106.0 224.1 15.9 162.1 102.7 95.8 8.0 31.1 222.8 446.5 104.6 146.9 223.1 458.4 657.6 134.9 47.5 111.7 66.8 143.8 112.6 79.7 175.6 166.1 82.2 112.8 249.9 348.8 176.8 MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Proximal tubular cells: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cell Junctions" "HPA050166: AB_2681039, HPA076046: " "unprognostic (1.42e-1)" "unprognostic (6.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-2)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (4.64e-3)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "prognostic favorable (2.09e-6)" "unprognostic (7.73e-2)" "unprognostic (9.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.63e-1)" 25.1 51.5 20.3 12.9 21.7 11.3 22.7 23.7 25.4 14.6 22.0 24.2 20.0 17.1 18.2 26.4 17.1 13.0 76.1 20.8 23.6 34.7 70.9 12.7 20.9 23.1 22.1 17.2 16.2 24.6 16.2 19.6 23.6 14.9 23.6 16.8 17.1 15.2 73.3 17.9 19.7 18.4 21.7 19.1 24.8 28.1 22.7 18.9 17.2 84.6 20.3 20.7 16.2 22.6 27.8 87.2 27.2 29.8 38.0 28.6 51.5 38.6 35.5 56.9 50.4 108.6 59.3 64.9 38.6 34.9 51.0 65.9 107.4 47.4 44.8 26.3 86.4 53.6 61.5 114.3 24.6 54.2 40.4 32.7 56.6 42.8 28.7 29.0 50.2 63.2 60.7 26.6 42.7 59.6 44.2 68.4 43.5 50.5 52.9 51.9 37.9 49.2 44.5 88.2 42.1 26.5 36.6 57.7 81.8 44.6 64.8 65.7 31.3 44.0 41.9 23.3 56.4 24.2 55.7 53.0 48.5 58.1 34.2 27.1 45.5 33.7 60.0 60.5 69.6 78.8 63.3 58.7 58.7 69.5 69.5 61.6 7.9 62.9 45.0 50.5 68.0 61.5 20.3 21.7 23.7 25.4 20.8 23.6 23.1 22.1 23.6 21.7 22.7 22.6 18.9 0.0 10.3 5.2 21.0 13.8 22.4 59.8 9.6 21.2 17.3 21.3 70.4 37.1 32.3 36.8 27.1 94.3 10.7 20.4 119.3 35.0 67.1 20.0 16.6 18.4 28.3 17.7 4.2 38.0 42.1 19.2 19.9 19.5 22.2 25.8 17.2 105.0 35.6 15.2 5.9 20.6 44.7 13.4 5.5 16.3 14.3 10.8 7.2 3.7 42.1 25.1 20.6 4.5 6.1 31.7 18.4 18.8 17.3 21.9 32.1 133.6 26.2 28.4 26.3 19.5 25.5 55.3 27.4 27.1 23.3 80.7 18.5 66.9 36.1 29.4 MRPS24 "HSPC335, MRP-S24" ENSG00000062582 "Mitochondrial ribosomal protein S24" Q96EL2 7 43866558-43869893 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 455.8" "Group enriched" "Detected in many" 5 "Basal squamous epithelial cells: 109.3;Erythroid cells: 54.7;Gastric mucus-secreting cells: 84.6;Plasma cells: 184.7;Squamous epithelial cells: 204.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073947 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" "HPA073947: " "unprognostic (1.35e-1)" "unprognostic (2.41e-2)" "unprognostic (1.30e-1)" "unprognostic (3.44e-1)" "unprognostic (7.32e-2)" "unprognostic (8.63e-3)" "unprognostic (9.42e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (2.03e-1)" "unprognostic (6.86e-3)" "unprognostic (9.58e-3)" "unprognostic (1.71e-2)" "prognostic favorable (9.89e-4)" "unprognostic (2.87e-1)" "unprognostic (9.08e-2)" "unprognostic (7.37e-2)" "unprognostic (1.95e-1)" 81.4 160.7 98.6 41.6 98.8 93.6 81.9 103.5 116.1 82.3 103.6 107.5 71.6 79.2 43.3 148.5 79.7 34.0 233.6 100.1 104.1 142.9 172.6 64.4 49.4 96.2 97.7 95.8 151.1 92.0 68.3 39.7 96.2 82.4 47.0 31.3 101.2 40.1 455.8 91.7 77.7 37.8 97.1 76.9 126.8 83.5 106.1 47.9 65.3 281.0 48.3 87.3 88.4 94.7 165.2 260.4 80.2 165.8 82.7 141.4 132.3 155.4 386.0 206.2 203.3 236.7 152.8 140.1 182.8 160.1 278.8 204.7 115.8 142.9 160.9 131.8 287.2 86.1 286.2 287.7 122.7 140.5 106.5 133.8 142.6 161.0 192.1 130.8 120.3 136.8 281.4 103.3 131.6 262.7 170.6 313.4 200.5 184.8 261.0 137.3 113.9 540.5 150.9 139.3 159.5 180.4 156.7 386.3 162.2 102.9 261.5 252.1 96.8 191.6 263.6 116.1 225.7 310.4 258.8 182.5 232.3 186.1 305.7 41.4 175.4 95.6 114.1 181.6 124.8 222.5 167.5 137.5 241.0 195.6 165.0 142.6 14.7 124.1 181.0 162.8 214.1 177.5 98.6 98.8 103.5 116.1 100.1 104.1 96.2 97.7 96.2 97.1 106.1 94.7 1.2 6.4 19.1 0.0 24.1 4.5 2.6 2.5 109.3 4.9 8.2 5.3 0.4 8.6 13.2 5.5 6.2 1.4 2.9 1.8 3.9 7.1 1.8 9.4 16.5 7.8 4.2 54.7 0.0 0.7 3.8 20.4 84.6 12.1 3.8 2.3 8.9 21.7 1.2 0.0 0.0 1.5 0.0 8.6 6.3 1.0 0.3 24.4 3.6 0.0 3.1 0.9 4.1 0.0 0.0 2.9 0.7 0.7 184.7 1.8 1.6 1.9 21.9 7.7 0.0 1.7 13.8 1.0 1.4 204.4 5.8 1.9 19.4 1.7 2.1 3.2 MRPS27 KIAA0264 ENSG00000113048 "Mitochondrial ribosomal protein S27" Q92552 5 72219403-72320646 "Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071751 Approved Supported Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "HPA071751: AB_2686442" "unprognostic (3.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.14e-3)" "unprognostic (3.60e-2)" "unprognostic (2.23e-2)" "unprognostic (1.63e-1)" "unprognostic (1.79e-2)" "unprognostic (7.20e-3)" "unprognostic (2.12e-1)" "unprognostic (3.22e-3)" "unprognostic (5.07e-2)" "unprognostic (3.26e-2)" "unprognostic (6.58e-3)" "unprognostic (1.33e-1)" "unprognostic (5.27e-2)" "unprognostic (7.73e-2)" "unprognostic (3.95e-2)" 25.5 36.1 23.8 21.8 25.3 18.9 31.8 23.6 27.8 27.0 33.8 26.2 20.4 25.8 27.6 32.4 31.3 19.0 55.5 25.0 23.1 30.5 38.5 17.5 36.9 24.6 24.1 39.5 27.1 32.7 20.9 21.2 24.6 25.2 31.5 17.7 22.4 30.3 58.7 31.7 22.0 26.9 24.5 25.9 25.7 15.1 25.0 30.7 35.6 89.1 41.9 29.7 26.0 24.1 49.7 65.2 56.8 94.4 73.1 93.5 73.0 46.7 66.4 86.9 69.7 81.9 68.5 128.2 63.8 54.8 94.9 54.0 111.8 166.1 93.6 48.6 69.2 66.0 71.3 91.1 72.7 58.4 49.0 88.1 68.7 91.3 101.5 79.0 94.2 92.2 67.2 37.5 73.0 59.7 87.8 70.4 65.7 35.8 40.4 92.0 94.4 131.5 80.7 52.4 87.5 46.7 78.5 63.8 58.5 52.2 97.8 69.9 54.1 35.3 51.8 50.3 85.2 37.7 61.0 89.1 60.9 94.6 57.0 15.5 23.4 8.1 24.9 27.5 37.1 36.1 30.6 30.4 44.2 32.1 35.2 37.9 3.2 43.3 23.0 16.6 34.6 31.5 23.8 25.3 23.6 27.8 25.0 23.1 24.6 24.1 24.6 24.5 25.0 24.1 13.9 9.6 11.7 32.7 27.6 20.4 22.3 21.6 23.3 11.4 26.5 22.2 101.9 7.2 15.6 11.0 16.7 41.5 18.6 9.1 25.4 20.5 2.2 16.1 21.8 17.2 16.2 36.8 43.9 17.3 48.2 18.8 17.9 12.1 7.6 29.3 15.7 34.8 24.8 10.1 38.4 21.0 8.2 28.6 13.3 4.4 19.0 15.0 10.6 30.0 31.4 15.3 17.5 38.7 51.1 14.9 15.3 25.2 16.8 13.5 10.7 28.8 12.6 13.2 13.1 18.2 17.6 10.3 18.7 32.3 17.6 28.9 21.2 30.4 31.4 14.8 MRPS28 "HSPC007, MRP-S28, MRPS35" ENSG00000147586 "Mitochondrial ribosomal protein S28" Q9Y2Q9 8 79918717-80030289 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 359.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027202 Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA027202: AB_1854126" "unprognostic (3.63e-3)" "unprognostic (6.41e-2)" "unprognostic (9.61e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-3)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (4.55e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "prognostic favorable (1.20e-6)" "unprognostic (4.48e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-1)" "unprognostic (7.18e-2)" 47.5 88.8 65.1 32.9 67.7 29.1 47.5 70.0 85.3 33.3 73.0 52.9 30.9 27.3 38.3 41.0 35.2 28.8 104.0 64.0 70.2 79.2 110.9 30.4 37.7 70.1 69.8 28.6 32.3 69.6 40.4 40.9 70.1 31.3 41.0 51.7 35.4 33.4 160.3 29.0 29.4 32.8 69.7 26.7 35.3 24.3 66.9 44.9 53.7 137.7 37.9 39.0 30.7 75.3 85.2 84.1 73.0 17.3 60.9 77.2 79.8 94.3 85.7 122.1 104.2 74.0 66.4 107.2 105.3 75.6 124.2 68.5 102.1 105.5 99.0 85.3 89.8 128.8 74.8 114.4 67.7 57.6 55.3 66.4 88.9 71.8 97.4 67.1 81.0 85.2 93.4 42.3 123.7 81.3 133.8 93.5 29.8 219.5 139.5 89.9 58.1 62.0 158.0 81.8 34.8 58.6 41.1 359.5 91.1 83.8 86.6 68.1 59.0 45.8 116.4 81.6 82.7 46.5 81.4 97.2 77.4 66.7 36.8 95.4 53.8 29.1 48.2 77.3 52.3 51.2 52.8 59.4 98.8 54.4 64.1 62.1 11.1 71.5 70.1 111.1 73.0 49.8 65.1 67.7 70.0 85.3 64.0 70.2 70.1 69.8 70.1 69.7 66.9 75.3 32.5 22.4 22.2 57.8 20.8 35.2 19.5 124.5 36.5 10.9 23.4 28.1 51.6 42.9 67.0 33.1 4.2 78.7 20.9 18.1 101.8 67.3 15.1 28.5 16.1 26.2 37.3 21.7 39.0 47.4 74.3 21.2 17.9 24.1 50.0 10.5 23.9 65.5 49.5 5.0 42.5 23.5 69.2 25.5 28.5 10.4 17.7 26.9 44.4 70.3 40.0 23.7 26.8 93.5 81.8 36.0 20.6 22.2 19.9 13.4 24.5 126.9 79.7 17.2 32.9 31.1 26.1 18.6 33.4 41.6 37.8 59.4 20.0 23.2 36.4 16.0 MRPS33 CGI-139 ENSG00000090263 "Mitochondrial ribosomal protein S33" Q9Y291 7 141002610-141015228 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 354.1;Proximal tubular cells: 386.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030425 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA030425: AB_10602030" "unprognostic (9.83e-2)" "unprognostic (2.91e-1)" "unprognostic (2.19e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-2)" "unprognostic (4.03e-2)" "unprognostic (5.99e-2)" "unprognostic (3.82e-1)" "unprognostic (3.66e-2)" "unprognostic (4.55e-3)" "unprognostic (6.94e-3)" "unprognostic (4.26e-1)" "unprognostic (9.80e-3)" "unprognostic (1.16e-1)" "unprognostic (9.52e-2)" "unprognostic (1.01e-1)" "unprognostic (3.52e-2)" 37.7 64.4 43.9 27.5 46.9 25.0 58.5 46.4 68.8 30.3 47.7 65.3 50.1 25.5 79.1 46.3 35.1 22.4 114.5 45.3 48.0 72.7 83.7 20.8 41.0 46.6 45.9 35.2 67.6 81.2 49.1 24.4 48.0 36.6 69.8 29.4 50.0 31.2 173.7 35.9 44.5 26.5 46.8 30.9 44.3 45.3 45.4 41.9 51.7 171.5 43.5 36.9 30.2 47.8 79.0 110.5 61.8 65.7 77.1 104.9 67.6 69.5 68.7 65.1 73.2 67.6 104.9 107.7 100.0 67.3 140.9 50.5 69.5 102.6 89.3 96.6 83.1 67.8 20.6 130.8 93.8 98.3 39.2 99.8 103.0 100.8 89.4 73.3 53.9 108.4 113.3 84.0 128.2 124.8 110.1 153.3 129.3 140.0 125.6 28.4 48.5 186.1 114.9 99.8 111.7 88.2 93.7 93.2 145.5 65.3 79.4 90.8 41.8 56.6 38.4 137.5 75.8 128.3 155.7 126.8 125.3 99.8 95.1 13.0 47.6 37.9 48.9 68.7 61.9 85.4 85.5 61.1 79.5 66.8 98.3 83.5 4.9 79.8 60.5 93.8 77.3 61.2 43.9 46.9 46.4 68.8 45.3 48.0 46.6 45.9 48.0 46.8 45.4 47.8 30.3 38.5 43.6 11.1 54.6 42.6 72.1 207.7 51.2 27.1 101.1 104.6 333.5 82.9 96.5 114.0 31.3 145.4 39.5 96.9 354.1 101.0 136.8 124.2 60.1 42.8 89.7 46.3 8.9 136.8 133.0 55.3 50.0 70.6 48.2 71.4 42.5 221.8 114.1 57.2 9.1 148.3 109.9 59.8 38.1 41.0 57.8 45.7 76.5 8.4 97.4 47.8 51.5 9.0 18.0 95.6 80.6 42.5 88.9 67.1 199.0 386.1 122.5 32.9 19.7 41.0 57.1 157.7 50.8 84.4 45.7 116.8 49.6 82.8 202.3 79.0 MRPS36 "DC47, MRP-S36" ENSG00000134056 "Mitochondrial ribosomal protein S36" P82909 5 69217760-69230158 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 546.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035802, HPA056795" Supported Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA035802: AB_10600933, HPA056795: AB_2683237" "unprognostic (1.19e-1)" "unprognostic (6.78e-3)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (2.96e-3)" "unprognostic (1.99e-1)" "unprognostic (7.49e-2)" "unprognostic (1.49e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (3.90e-1)" "prognostic favorable (5.02e-6)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.37e-2)" "unprognostic (4.84e-3)" 20.3 18.4 20.1 12.7 20.3 21.0 16.5 21.3 26.3 12.7 20.2 23.6 24.1 12.8 15.4 20.3 12.7 10.4 67.3 20.1 21.5 49.2 38.0 14.7 15.1 20.3 20.6 12.4 14.7 31.3 9.8 13.0 20.6 14.4 24.3 18.9 13.7 12.1 47.0 12.6 24.0 12.4 20.3 11.6 21.8 8.6 20.8 15.7 17.2 67.7 16.7 16.6 14.0 20.5 29.2 27.6 19.1 26.4 32.8 33.1 50.3 25.6 24.5 32.1 39.4 38.6 31.8 31.2 51.9 21.8 71.8 29.3 32.1 38.8 31.7 36.8 33.6 21.3 31.4 43.4 38.7 22.9 27.9 34.6 27.3 30.7 14.5 33.4 24.0 31.9 25.7 22.9 28.7 31.8 35.3 34.9 14.2 26.8 31.9 20.6 33.2 47.9 56.4 32.5 26.6 25.9 26.2 37.9 46.3 30.9 29.0 32.9 17.6 14.3 24.5 32.0 44.5 23.9 41.9 41.6 25.0 42.1 19.1 36.3 22.1 29.3 22.7 32.0 25.4 31.1 25.7 25.8 27.9 25.0 22.8 24.7 25.1 26.5 30.2 27.4 40.3 17.7 20.1 20.3 21.3 26.3 20.1 21.5 20.3 20.6 20.6 20.3 20.8 20.5 64.5 115.4 83.6 16.3 76.5 81.4 101.1 204.0 83.1 26.3 72.4 109.3 333.1 97.2 104.3 88.3 14.6 126.8 67.5 220.5 401.1 118.4 127.7 123.3 79.5 57.2 92.8 97.2 20.4 139.5 192.4 68.6 67.2 113.0 56.4 41.4 52.1 216.1 127.1 28.6 21.4 162.8 120.1 102.4 67.5 45.2 64.7 72.9 106.7 10.3 142.0 61.8 56.7 10.6 17.1 137.1 190.1 69.2 60.5 100.5 256.6 546.3 86.4 45.9 72.3 78.7 92.3 66.1 37.9 86.9 76.9 123.3 64.2 76.9 168.1 114.6 MRPS7 "MRP-S, RP-S7, RPMS7" ENSG00000125445 "Mitochondrial ribosomal protein S7" Q9Y2R9 17 75261674-75266376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 454.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022522, HPA023007" Supported Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA022522: AB_1854131, HPA023007: AB_1854132" "unprognostic (1.24e-1)" "unprognostic (4.74e-2)" "prognostic favorable (1.12e-4)" "unprognostic (5.82e-3)" "unprognostic (3.62e-2)" "unprognostic (5.05e-3)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (4.95e-2)" "unprognostic (8.56e-3)" "unprognostic (1.03e-1)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (8.56e-2)" "unprognostic (1.76e-1)" "unprognostic (4.15e-1)" 44.3 58.4 55.5 38.1 55.9 32.9 41.2 60.0 61.9 28.7 59.0 49.9 48.9 28.3 24.4 58.5 39.2 27.1 129.0 55.1 59.3 66.1 64.6 32.4 41.3 57.2 57.5 29.2 39.0 76.6 36.0 40.8 57.6 34.1 48.2 47.3 41.1 35.7 201.3 32.6 40.0 33.8 57.8 39.5 47.5 29.9 59.8 33.6 35.9 212.3 43.6 42.6 35.0 56.3 113.8 188.6 78.8 57.6 63.9 35.7 139.4 73.3 60.9 137.4 101.1 209.8 93.5 96.4 66.4 79.8 91.4 104.5 122.3 135.8 82.2 50.8 173.5 131.8 133.6 201.3 62.5 134.3 69.6 60.0 131.8 108.6 109.6 69.2 177.3 117.8 130.1 93.3 91.1 203.5 151.8 104.7 85.4 157.7 176.2 100.7 229.5 145.2 128.4 124.6 135.8 122.8 93.8 249.9 150.0 83.9 188.4 108.7 72.2 124.0 125.3 68.2 155.7 97.9 61.5 106.6 89.5 88.3 96.9 43.2 155.1 48.2 115.7 161.6 124.2 140.2 112.0 126.0 172.0 128.1 128.6 120.7 11.0 130.5 138.5 164.9 141.6 236.0 55.5 55.9 60.0 61.9 55.1 59.3 57.2 57.5 57.6 57.8 59.8 56.3 44.1 51.3 48.3 12.1 69.3 39.5 75.1 148.1 37.0 65.8 56.5 63.0 77.8 70.1 74.3 57.0 98.0 192.9 63.3 94.1 230.9 112.9 139.2 50.9 43.2 55.6 47.5 61.4 11.8 104.1 175.3 50.2 55.5 43.5 39.3 68.6 45.3 91.7 148.8 47.1 14.0 84.3 77.3 60.0 35.6 454.3 48.4 52.6 42.7 3.7 107.0 85.6 73.2 9.5 11.3 89.8 69.3 39.9 87.7 85.3 129.2 219.3 81.0 114.4 59.2 40.8 73.0 60.5 68.5 68.5 41.9 137.9 53.8 110.0 133.8 77.4 MRPS9 "MRP-S9, RPMS9, S9mt" ENSG00000135972 "Mitochondrial ribosomal protein S9" P82933 2 105038069-105099960 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043476, HPA048479" Supported Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA043476: AB_2678498, HPA048479: AB_2680412" "unprognostic (8.10e-3)" "unprognostic (4.75e-3)" "unprognostic (3.69e-1)" "unprognostic (3.80e-3)" "unprognostic (5.25e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (3.78e-1)" "unprognostic (2.62e-3)" "unprognostic (4.62e-2)" "unprognostic (5.28e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" 17.2 33.5 21.4 17.9 22.7 24.6 23.3 24.1 26.5 18.3 25.7 29.8 29.5 20.7 19.2 23.8 24.2 13.4 64.1 21.4 23.3 32.7 31.8 15.4 24.7 24.0 22.8 30.8 24.2 32.8 19.6 12.9 24.3 23.4 33.3 22.3 23.3 21.6 98.6 21.9 23.4 19.8 22.7 18.5 25.9 33.5 22.8 30.8 21.4 97.0 27.1 20.2 17.9 25.1 68.2 28.9 59.4 55.1 30.6 31.5 69.6 42.6 40.6 66.2 59.2 155.0 46.4 70.6 41.1 33.9 68.9 59.8 118.0 62.1 69.9 44.0 77.5 69.7 42.4 94.4 51.0 52.2 29.9 37.9 41.5 54.6 45.4 38.3 51.6 84.8 101.5 35.9 45.7 54.9 70.6 68.6 93.9 57.4 62.6 88.9 50.9 98.3 83.2 47.3 51.4 30.9 49.4 71.5 59.9 58.0 58.9 52.2 34.0 38.8 78.2 38.9 46.6 32.6 41.5 56.3 33.6 79.1 33.3 21.7 23.8 10.1 39.3 31.5 43.3 44.4 43.0 41.7 43.0 35.3 42.9 42.4 2.8 46.0 39.9 32.1 49.9 31.7 21.4 22.7 24.1 26.5 21.4 23.3 24.0 22.8 24.3 22.7 22.8 25.1 18.2 22.4 28.2 28.1 21.0 19.5 25.3 56.4 22.2 24.7 15.4 22.2 110.2 22.8 30.4 22.0 12.5 39.9 29.1 17.7 107.6 40.7 51.7 35.9 18.6 22.5 19.7 47.5 43.4 42.7 40.7 21.2 18.8 12.9 22.8 34.6 18.2 31.2 28.8 8.4 54.2 27.9 24.4 15.2 9.9 14.6 23.9 15.9 30.2 17.8 26.2 21.2 29.9 49.3 69.4 22.6 18.3 27.1 25.0 17.4 23.1 72.3 42.1 32.0 39.5 24.8 28.1 112.8 40.7 23.4 13.2 20.4 25.2 62.9 40.5 19.0 MRS2 MRS2L ENSG00000124532 "Magnesium transporter MRS2" Q9HD23 6 24402908-24426194 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017642 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA017642: AB_2669628" "unprognostic (2.12e-3)" "unprognostic (1.22e-1)" "unprognostic (5.64e-3)" "prognostic unfavorable (5.32e-4)" "unprognostic (7.23e-2)" "unprognostic (8.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-1)" "unprognostic (3.89e-3)" "prognostic favorable (5.14e-11)" "unprognostic (8.75e-2)" "unprognostic (2.94e-2)" "unprognostic (8.32e-2)" "unprognostic (2.53e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.55e-3)" 14.6 17.0 10.7 12.0 11.8 6.7 14.3 17.1 13.7 10.9 15.4 14.1 15.4 10.3 14.1 14.1 10.2 9.3 30.7 11.2 12.2 24.2 20.5 10.9 14.9 10.8 11.7 12.3 18.8 22.5 13.4 16.4 11.2 12.8 15.4 30.1 15.9 13.4 52.9 12.3 12.1 10.7 10.9 11.4 15.7 6.3 12.2 8.7 16.3 49.4 14.8 13.2 11.5 11.4 36.7 21.0 24.7 46.3 15.9 14.4 54.8 16.6 19.3 20.5 18.5 80.9 16.9 21.2 67.3 14.6 32.2 21.8 25.6 31.6 22.0 26.8 44.9 33.6 16.4 93.7 23.0 38.7 30.0 22.8 24.7 20.9 16.7 23.8 22.2 27.2 49.5 0.0 22.6 28.9 37.1 35.3 64.6 20.6 18.9 0.2 4.3 48.4 90.5 37.1 39.3 23.7 28.1 84.9 46.5 72.0 43.3 26.3 9.6 9.1 13.8 18.9 30.8 37.4 68.1 29.4 11.3 45.4 38.3 3.4 16.8 7.3 11.6 20.2 14.9 14.4 12.4 12.5 24.8 11.9 13.4 12.6 1.9 15.3 18.8 14.8 11.5 12.1 10.7 11.8 17.1 13.7 11.2 12.2 10.8 11.7 11.2 10.9 12.2 11.4 10.5 35.3 20.0 18.6 18.0 7.1 13.6 18.8 16.5 33.5 15.7 10.4 55.6 20.0 16.4 20.2 39.6 46.5 23.3 13.6 52.8 22.6 0.6 15.7 11.5 11.3 9.6 17.1 33.7 19.1 24.6 14.8 13.3 12.9 12.0 23.3 11.4 14.4 21.9 50.5 35.6 15.4 22.4 15.8 10.0 0.7 12.2 14.8 7.2 9.4 19.6 21.8 16.5 15.1 16.5 15.9 14.9 16.6 19.7 14.7 20.0 40.7 14.4 43.6 19.7 9.2 12.9 5.4 11.6 22.7 11.2 25.3 13.1 27.2 22.3 15.7 MT1HL1 MT1P2 ENSG00000244020 "Metallothionein 1H like 1" P0DM35 1 237004103-237004441 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "heart muscle: 5.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 7.9;Hepatocytes: 14.7;Paneth cells: 8.8;Proximal tubular cells: 48.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (5.79e-2)" "unprognostic (2.78e-1)" "unprognostic (2.65e-1)" "unprognostic (3.77e-2)" 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.9 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 7.9 0.0 0.0 0.6 0.1 0.3 0.0 0.0 0.0 0.0 2.0 0.5 0.0 1.5 0.0 0.0 0.4 14.7 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 1.4 4.1 48.0 0.0 0.0 0.0 1.8 1.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 0.9 0.0 MTCP1 "P13MTCP1, p8MTCP1, TCL1C" ENSG00000214827 "Mature T cell proliferation 1" P56278 X 155064034-155147937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Respiratory ciliated cells: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 13.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA032040 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA032040: AB_2674122" "unprognostic (2.42e-2)" "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (6.29e-3)" "unprognostic (8.30e-2)" "unprognostic (4.10e-1)" "unprognostic (2.40e-5)" "unprognostic (9.30e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-2)" "unprognostic (5.72e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (4.52e-8)" "unprognostic (1.55e-3)" "unprognostic (1.06e-2)" "unprognostic (1.39e-2)" "unprognostic (1.75e-2)" 1.0 2.1 0.8 1.9 1.1 2.8 1.8 1.7 1.4 1.3 1.1 1.6 2.0 1.7 2.7 1.2 1.4 1.3 1.4 0.8 1.0 1.8 2.5 1.2 2.5 1.1 0.9 2.3 2.6 1.0 1.7 1.0 1.0 1.7 2.0 2.5 1.6 1.4 1.2 4.2 1.8 1.4 0.9 1.9 2.0 5.3 1.0 1.9 1.9 0.7 2.5 1.4 0.9 1.2 1.2 3.9 1.9 3.1 1.2 1.0 2.1 2.4 1.2 1.5 3.7 3.5 6.0 2.2 2.4 0.5 2.4 3.9 2.6 2.8 1.9 1.5 2.5 1.0 13.6 1.9 1.1 2.4 2.5 1.9 1.3 2.5 2.4 1.8 1.4 3.8 0.9 3.9 1.1 1.7 3.2 5.1 0.9 1.5 0.6 3.4 2.0 5.1 2.0 1.7 0.9 1.4 1.7 1.0 1.7 1.3 1.8 1.1 1.5 1.8 3.0 1.7 1.9 8.6 4.1 4.4 3.4 2.9 2.6 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.8 1.1 1.7 1.4 0.8 1.0 1.1 0.9 1.0 0.9 1.0 1.2 0.5 0.0 1.5 0.0 0.5 0.3 0.3 0.7 0.6 0.0 0.6 0.5 1.4 1.5 1.4 0.0 0.0 0.2 0.8 0.6 0.0 0.8 0.0 0.7 0.3 0.5 1.8 3.2 0.0 1.2 0.4 0.6 0.0 0.6 0.0 2.2 0.4 2.0 0.4 0.0 0.0 0.0 0.0 1.0 0.3 0.6 1.2 0.8 1.8 0.0 1.0 0.0 1.0 0.0 0.0 1.0 0.2 0.4 0.9 0.3 0.3 0.3 2.4 0.0 0.0 0.6 0.4 0.6 0.2 0.4 0.9 0.3 0.7 0.8 0.5 0.1 MTERF2 "FLJ14062, MTERFD3" ENSG00000120832 "Mitochondrial transcription termination factor 2" Q49AM1 12 106977277-106987160 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003526 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA003526: AB_1079423" "unprognostic (1.54e-2)" "prognostic favorable (8.50e-4)" "unprognostic (1.17e-1)" "unprognostic (4.87e-2)" "unprognostic (7.62e-2)" "unprognostic (7.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.37e-3)" "unprognostic (1.15e-2)" "unprognostic (2.57e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-2)" "unprognostic (2.62e-2)" "unprognostic (1.56e-1)" "unprognostic (2.88e-2)" "unprognostic (1.29e-1)" "unprognostic (1.24e-3)" 14.3 24.8 23.3 6.3 23.5 6.4 17.3 31.1 27.7 19.6 23.6 25.7 17.5 16.0 13.1 9.6 16.9 12.9 31.5 23.0 24.8 28.1 29.1 15.1 8.1 22.2 23.1 21.5 34.0 12.7 20.2 7.1 22.9 22.5 9.8 30.2 15.5 11.8 23.0 22.3 16.6 11.7 22.4 15.1 22.4 17.6 24.6 6.5 30.4 16.3 5.5 16.0 13.3 23.2 10.3 13.0 14.5 20.6 16.7 8.5 7.0 10.0 5.2 8.1 8.5 8.2 7.2 7.0 10.5 6.7 6.6 10.0 11.1 5.4 6.7 14.2 13.2 23.9 18.4 14.5 12.6 0.0 7.8 15.2 9.7 8.1 5.9 13.0 10.5 0.5 31.8 6.9 9.8 7.8 3.3 10.6 7.4 4.2 13.0 10.3 13.0 4.4 14.6 11.9 14.3 16.5 13.4 18.0 18.4 13.4 26.0 9.3 10.0 9.1 6.1 7.3 8.3 14.7 19.4 6.7 3.5 2.4 13.8 0.3 0.7 3.0 11.8 2.1 10.1 2.8 11.1 9.3 5.2 2.8 9.1 9.8 5.0 7.2 1.3 11.0 10.7 5.8 23.3 23.5 31.1 27.7 23.0 24.8 22.2 23.1 22.9 22.4 24.6 23.2 11.7 35.3 11.4 24.8 4.3 0.0 20.2 0.0 8.0 0.0 23.6 21.7 20.1 27.1 4.3 14.7 0.0 10.8 19.3 1.8 39.2 6.3 32.3 10.7 16.6 9.1 3.6 12.4 13.9 6.4 8.7 12.7 10.2 10.7 5.1 15.0 10.4 16.8 7.0 0.0 20.6 4.4 0.0 3.2 0.0 12.1 20.2 3.8 0.0 2.8 4.3 0.0 16.5 16.1 15.3 3.6 7.6 24.8 4.8 6.7 8.5 27.1 6.6 0.0 13.1 27.1 10.3 17.7 10.7 5.7 0.0 4.2 10.8 20.6 8.1 7.3 MTFR1L FAM54B ENSG00000117640 "Mitochondrial fission regulator 1 like" Q9H019 1 25818640-25832942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 161.1;Early spermatids: 216.1;Late spermatids: 590.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027124, HPA027130" Approved Approved "Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Cell Junctions" "HPA027124: AB_10600211, HPA027130: AB_10611251" "unprognostic (9.90e-2)" "unprognostic (6.86e-3)" "unprognostic (9.29e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.52e-3)" "unprognostic (2.12e-1)" "unprognostic (2.24e-1)" "unprognostic (9.89e-3)" "unprognostic (5.33e-2)" "prognostic favorable (5.89e-12)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.69e-1)" "unprognostic (1.33e-1)" 39.0 138.0 79.6 22.2 82.8 17.8 37.4 80.0 88.4 51.0 84.6 74.1 46.8 51.0 57.8 39.4 44.9 32.7 169.1 81.7 81.3 71.7 91.3 32.4 25.8 80.2 83.8 68.4 46.0 106.0 51.6 40.7 79.6 55.8 37.3 62.1 43.3 70.1 221.8 35.6 46.9 50.0 78.6 44.2 56.6 82.5 83.2 24.7 48.1 239.7 26.3 58.3 40.5 78.5 19.5 26.7 53.2 53.6 67.6 63.8 22.2 44.7 63.7 45.2 49.9 8.7 39.7 6.6 38.9 80.1 40.0 17.4 44.1 38.6 44.8 43.9 39.8 55.6 44.3 35.9 64.6 45.5 52.9 65.3 36.4 48.3 36.1 67.0 37.9 27.0 34.7 29.2 66.1 21.6 26.3 33.6 29.4 26.0 39.4 26.0 47.4 19.8 47.1 18.3 53.6 48.5 33.6 32.4 67.8 35.8 26.7 43.1 38.6 36.7 28.9 86.6 28.5 30.5 19.3 23.2 63.6 62.5 41.2 71.7 50.5 111.7 25.7 50.8 15.6 28.1 24.1 22.9 55.0 28.8 25.4 23.1 13.6 27.6 58.3 22.7 27.3 51.1 79.6 82.8 80.0 88.4 81.7 81.3 80.2 83.8 79.6 78.6 83.2 78.5 18.7 16.0 24.5 24.2 14.1 13.5 20.8 38.6 25.0 0.0 21.6 23.6 161.1 25.8 21.7 22.0 0.0 55.9 14.8 15.7 103.7 32.4 216.1 11.3 16.7 17.1 15.6 12.4 18.2 33.5 36.7 28.4 21.4 10.6 36.1 21.9 21.4 35.5 34.9 0.0 24.1 14.9 34.6 15.1 17.3 590.4 34.2 25.6 44.4 6.5 43.5 0.0 12.3 12.5 15.2 27.7 15.0 39.1 15.4 16.2 39.3 70.6 10.5 0.0 26.3 23.3 31.3 144.7 49.9 15.4 12.9 59.4 13.1 29.8 18.0 16.5 MTIF3 "IF-3mt, IF3(mt)" ENSG00000122033 "Mitochondrial translational initiation factor 3" Q9H2K0 13 27435643-27450591 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 610.0;Proximal tubular cells: 475.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039791 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA039791: AB_10795296" "unprognostic (1.82e-1)" "unprognostic (1.44e-2)" "unprognostic (2.59e-1)" "unprognostic (3.26e-3)" "unprognostic (1.49e-2)" "unprognostic (8.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (3.77e-1)" "unprognostic (1.64e-2)" "unprognostic (1.62e-1)" "unprognostic (2.40e-1)" "unprognostic (3.24e-2)" "unprognostic (1.13e-1)" "unprognostic (9.27e-2)" "prognostic favorable (8.41e-4)" 61.8 55.0 59.5 29.2 59.8 17.1 51.0 61.0 93.4 36.7 60.4 46.7 42.8 28.4 67.1 39.9 30.4 37.0 133.4 59.0 61.7 63.1 65.5 29.2 44.5 60.9 60.2 37.1 54.4 43.4 50.8 30.9 60.9 45.3 44.6 74.7 82.9 43.9 90.8 39.9 41.8 30.5 58.8 49.6 48.1 61.8 60.6 47.3 36.9 109.8 46.1 36.7 34.0 62.0 29.9 21.9 48.5 23.5 53.2 78.8 22.6 44.0 51.1 33.8 33.8 28.3 37.5 33.3 28.4 50.8 22.8 25.1 27.2 37.1 46.3 34.3 31.2 42.6 19.1 36.7 52.2 43.8 38.8 44.6 65.5 27.7 35.1 75.6 60.0 33.8 24.0 13.6 51.2 54.0 39.7 54.2 24.4 100.1 24.0 22.8 24.3 37.5 69.8 31.3 32.9 20.6 28.4 39.1 50.7 51.8 31.3 62.5 38.1 21.4 12.5 56.1 29.5 10.0 14.9 19.1 21.5 44.3 31.1 85.8 53.0 75.4 30.8 51.2 32.9 49.1 38.9 31.1 55.2 42.8 34.0 35.2 36.5 37.2 48.3 88.2 47.4 41.3 59.5 59.8 61.0 93.4 59.0 61.7 60.9 60.2 60.9 58.8 60.6 62.0 88.5 28.9 47.4 29.0 74.0 34.0 34.0 103.9 43.9 0.0 91.6 95.4 179.1 87.2 76.3 115.8 0.0 102.6 60.4 102.2 326.8 89.6 610.0 93.7 63.4 70.3 64.1 59.7 22.8 104.1 67.0 62.7 47.4 74.5 71.7 50.6 79.9 223.0 102.3 0.0 26.4 112.8 103.7 114.8 50.2 283.4 139.8 67.7 106.7 24.4 106.4 0.0 80.3 30.7 43.7 98.3 108.8 124.8 71.1 43.7 142.8 475.5 83.2 0.0 124.9 48.8 69.2 243.6 87.6 62.8 42.5 56.8 58.5 69.6 96.8 44.8 MTLN "LEMP, LINC00116, MOXI, MPM, NCRNA00116, SMIM37" ENSG00000175701 Mitoregulin Q8NCU8 2 110211529-110245420 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 229.3;skeletal muscle: 784.7;tongue: 280.3" "Cell type enhanced" "Detected in some" "Adipocytes: 27.4;Cytotrophoblasts: 43.7;Extravillous trophoblasts: 32.8;Hofbauer cells: 78.4;Syncytiotrophoblasts: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.74e-2)" "unprognostic (1.86e-1)" "unprognostic (7.68e-2)" "unprognostic (6.99e-2)" "unprognostic (2.04e-1)" "unprognostic (2.64e-1)" "unprognostic (3.49e-3)" "unprognostic (8.20e-2)" "unprognostic (9.10e-2)" "unprognostic (6.08e-2)" "unprognostic (5.08e-3)" "unprognostic (8.27e-2)" "unprognostic (1.97e-1)" "unprognostic (2.93e-2)" "unprognostic (1.04e-1)" "unprognostic (8.80e-2)" "unprognostic (1.95e-2)" 66.5 68.9 67.3 22.2 71.2 10.1 51.1 80.5 103.8 42.0 63.5 73.9 41.6 58.0 52.1 63.5 41.6 9.2 229.3 68.8 77.2 69.8 78.0 40.2 15.9 75.8 71.4 33.6 46.2 37.0 41.3 12.9 75.6 48.6 12.4 11.0 43.9 34.0 784.7 44.6 46.8 16.7 70.4 44.4 57.3 25.7 78.1 18.5 48.0 280.3 12.0 55.7 46.1 75.6 0.4 125.0 13.3 15.3 14.7 17.5 81.1 49.9 38.6 58.7 39.2 86.0 39.7 16.9 95.0 13.8 81.4 52.9 13.2 57.5 9.6 72.0 51.4 10.1 30.5 73.3 61.2 35.6 50.3 45.6 67.8 48.8 0.0 31.8 52.9 50.2 28.6 40.6 28.1 130.0 49.8 121.6 34.1 39.9 36.9 5.5 28.0 51.9 37.2 77.9 29.5 19.4 27.7 95.2 57.1 8.9 26.4 59.2 41.0 57.7 81.3 56.9 75.9 67.8 48.0 5.3 60.0 56.1 42.1 9.6 101.9 13.8 109.6 112.1 125.1 104.0 123.5 118.7 110.6 115.0 129.1 129.1 5.6 85.9 67.6 150.2 119.0 77.4 67.3 71.2 80.5 103.8 68.8 77.2 75.8 71.4 75.6 70.4 78.1 75.6 27.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.7 8.7 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 32.8 11.8 0.0 0.0 0.0 0.0 0.0 0.0 78.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 20.2 1.5 0.0 0.0 0.0 MTTP "ABL, MTP" ENSG00000138823 "Microsomal triglyceride transfer protein" P55157 4 99564081-99623997 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 275.2;liver: 266.6" "Group enriched" "Detected in many" 9 "Hepatocytes: 244.2;Proximal enterocytes: 605.4" "Cancer enriched" "Detected in many" 13 "liver cancer: 28.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 10.8;Hep G2: 12.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA051170, HPA054862" Uncertain Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 640000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum, Cytosol" "HPA051170: , HPA054862: AB_2682628" "unprognostic (1.66e-2)" "unprognostic (1.14e-1)" "unprognostic (5.64e-2)" "unprognostic (5.33e-2)" "unprognostic (3.49e-3)" "unprognostic (7.38e-2)" "unprognostic (1.05e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (3.66e-2)" "unprognostic (1.00e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (2.02e-2)" "unprognostic (3.64e-1)" "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" 0.3 0.1 0.9 0.2 0.9 0.0 0.2 0.8 0.9 0.1 0.3 1.3 243.2 0.1 1.0 0.1 0.6 1.3 0.9 0.8 1.5 12.9 266.6 0.3 0.3 1.1 1.6 2.0 0.0 0.0 0.5 0.0 1.3 0.5 0.3 5.6 0.1 0.2 0.4 0.1 275.2 0.5 1.2 0.0 0.8 9.6 1.2 0.2 0.1 0.3 0.1 0.9 0.0 1.9 0.0 0.2 10.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.2 0.1 12.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.5 0.1 0.2 0.1 0.1 1.0 0.0 0.0 0.7 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.8 0.9 0.8 1.5 1.1 1.6 1.3 1.2 1.2 1.9 0.1 0.0 0.0 4.6 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.8 4.3 0.1 1.8 0.0 0.2 0.2 0.2 0.0 0.0 44.2 1.0 0.1 0.1 0.0 2.7 1.6 0.0 0.0 0.8 1.5 0.2 0.0 30.1 3.6 244.2 0.1 0.0 0.7 16.7 2.0 3.5 0.0 12.0 0.9 0.2 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.2 12.5 0.4 0.1 0.0 605.4 23.5 1.0 0.0 6.6 0.5 0.5 32.1 5.7 0.0 0.0 0.0 0.4 12.0 21.0 0.0 MUC22 PBMUCL1 ENSG00000261272 "Mucin 22" E2RYF6 6 31010474-31035402 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "esophagus: 17.8" "Cell type enriched" "Detected in single" 6 "Microglial cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (2.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (9.88e-2)" "unprognostic (1.14e-1)" "unprognostic (3.65e-1)" "unprognostic (1.35e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYADML2 LOC255275 ENSG00000185105 "Myeloid associated differentiation marker like 2" A6NDP7 17 81939645-81947233 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skeletal muscle: 84.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.0;Cardiomyocytes: 4.2;Early spermatids: 1.5;Excitatory neurons: 1.5;Horizontal cells: 1.7;Inhibitory neurons: 2.4;Skeletal myocytes: 1.0;Undifferentiated cells: 1.0" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041856, HPA048476" Uncertain NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 37: Myocytes - Muscle contraction" "HPA041856: AB_2677709, HPA048476: AB_2680410" "unprognostic (1.83e-1)" "unprognostic (1.71e-2)" "unprognostic (7.07e-2)" "unprognostic (2.90e-4)" "unprognostic (2.19e-1)" "unprognostic (1.79e-2)" "unprognostic (1.62e-4)" "unprognostic (1.48e-1)" "unprognostic (1.32e-1)" "unprognostic (6.09e-2)" "unprognostic (1.44e-2)" "unprognostic (3.37e-2)" "unprognostic (4.16e-7)" "unprognostic (1.86e-1)" "unprognostic (1.91e-1)" "unprognostic (8.68e-2)" 0.0 0.0 1.2 0.0 1.6 0.0 0.0 1.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 3.6 0.8 1.5 0.0 0.0 0.0 0.0 2.0 1.1 0.0 0.2 0.0 0.2 0.0 2.2 0.6 0.0 0.4 1.0 0.0 84.0 0.0 0.3 0.0 0.2 0.0 0.1 0.8 1.8 0.0 0.0 16.8 0.0 0.0 0.0 0.7 0.0 0.3 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.0 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.4 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 1.0 2.5 0.8 1.5 2.0 1.1 2.2 0.2 1.8 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.3 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 MYBPC1 ssMyBP-C ENSG00000196091 "Myosin binding protein C1" Q00872 12 101568353-101686028 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 87 "skeletal muscle: 11290.5;tongue: 5207.7" "Cell type enhanced" "Detected in some" "Astrocytes: 34.6;Breast glandular cells: 102.4;Breast myoepithelial cells: 81.4;Cardiomyocytes: 64.7;Skeletal myocytes: 184.6" "Cancer enhanced" "Detected in many" "prostate cancer: 33.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "HAP1: 6.8" "Group enriched" "Detected in many" 9 "cerebellum: 39.6;olfactory bulb: 10.6" "Region enhanced" "Detected in many" "thalamus: 6.9" "HPA021004, HPA027614" Enhanced NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA021004: AB_1854232, HPA027614: AB_10602711" "prognostic favorable (4.76e-5)" "unprognostic (7.72e-2)" "unprognostic (1.09e-1)" "unprognostic (1.81e-2)" "unprognostic (3.33e-2)" "unprognostic (4.63e-2)" "unprognostic (8.67e-2)" "unprognostic (2.93e-1)" "unprognostic (9.98e-3)" "unprognostic (2.56e-1)" "unprognostic (2.55e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-2)" "unprognostic (7.96e-2)" "unprognostic (6.13e-2)" "unprognostic (5.55e-3)" 1.5 0.3 55.5 0.1 66.5 0.0 63.7 60.4 71.6 1.9 36.3 4.5 0.1 0.2 1.1 94.7 0.8 0.3 1.8 50.1 59.5 0.3 0.7 0.7 0.0 52.3 64.5 0.5 1.1 0.0 0.3 0.0 55.0 83.5 0.8 0.0 48.4 0.3 11290.5 6.1 7.4 0.0 49.4 0.4 1.3 3.4 68.4 2.6 1.2 5207.7 4.0 0.3 0.7 49.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 66.5 60.4 71.6 50.1 59.5 52.3 64.5 55.0 49.4 68.4 49.9 1.3 0.0 0.0 34.6 0.3 0.0 2.2 0.0 0.0 0.0 102.4 81.4 64.7 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 16.5 0.1 0.1 1.2 0.0 0.0 5.3 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.8 0.3 23.7 0.6 1.2 1.8 1.0 0.0 0.0 0.0 0.5 0.5 0.1 1.6 0.4 0.0 16.3 0.3 0.1 0.0 0.0 0.0 184.6 2.7 1.4 1.4 0.0 0.0 0.0 0.7 0.0 0.3 2.9 MYL4 "ALC1, AMLC, GT1, PRO1957" ENSG00000198336 "Myosin light chain 4" P12829 17 47200446-47223679 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Atrial fibrillation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 47 "heart muscle: 6347.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2426.3" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 11.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.8" "Cell line enriched" "Detected in some" 4 "HEL: 552.8" "Group enriched" "Detected in all" 6 "amygdala: 25.8;cerebral cortex: 88.4;hippocampal formation: 25.2;white matter: 50.9" "Not detected" "Not detected" "HPA046859, HPA051884, HPA063034" Enhanced Approved "Plasma membrane" NA NA 3100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA046859: AB_2679842, HPA051884: AB_2681651, HPA063034: AB_2684927" "unprognostic (2.43e-2)" "unprognostic (9.57e-2)" "unprognostic (2.25e-1)" "unprognostic (5.51e-2)" "unprognostic (2.33e-1)" "unprognostic (4.12e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (6.52e-2)" "unprognostic (2.10e-2)" "unprognostic (7.37e-2)" "unprognostic (1.00e-6)" "unprognostic (1.92e-4)" "unprognostic (2.54e-1)" "unprognostic (6.51e-3)" "unprognostic (1.50e-1)" 2.1 0.5 0.2 0.4 0.3 134.6 2.7 0.2 0.4 0.4 0.4 0.8 0.8 0.8 0.0 0.6 0.5 1.0 6347.0 0.3 0.4 1.3 1.4 9.4 0.9 0.3 0.3 0.8 8.6 0.3 0.5 9.1 0.4 1.1 0.3 42.2 3.0 0.2 3.5 1.2 1.3 0.8 0.2 3.1 3.4 15.5 0.3 2.4 11.0 6.4 0.4 0.9 0.8 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.9 0.3 0.0 0.2 0.0 0.9 0.1 1.6 0.9 0.0 0.4 0.0 0.1 0.0 0.0 3.0 0.2 552.8 0.1 0.0 0.0 0.0 0.3 21.2 0.0 0.3 0.1 0.0 1.0 1.4 133.3 0.3 0.2 0.0 10.0 0.1 0.3 0.0 0.4 0.3 12.9 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 24.3 0.0 0.2 4.5 0.0 0.3 0.1 0.0 0.3 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.2 0.3 0.2 0.4 0.3 0.4 0.3 0.3 0.4 0.2 0.3 0.4 3.2 3.2 0.0 0.0 0.7 0.8 0.0 0.0 0.0 5.5 0.0 0.0 2426.3 0.0 0.0 0.0 64.6 0.5 2.7 0.1 0.0 0.1 23.3 0.1 0.0 23.2 0.0 412.8 0.1 0.0 3.9 150.7 1.5 0.1 0.0 0.3 1.8 0.5 1.9 1.7 0.0 0.8 0.0 0.6 0.6 54.6 3.4 34.0 12.4 0.0 1.5 7.9 4.1 0.0 0.1 0.1 0.0 1.5 0.8 0.0 10.9 0.2 0.0 24.4 0.0 0.6 36.5 9.9 0.5 0.0 0.9 1.4 0.3 0.2 1.0 0.0 MYL7 "MYL2A, MYLC2A" ENSG00000106631 "Myosin light chain 7" Q01449 7 44138864-44141332 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1061 "heart muscle: 23165.6" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 10772.7" "Cancer enriched" "Detected in some" 7 "testis cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BEWO: 35.6;CACO-2: 124.6;SuSa: 47.6" "Not detected" "Not detected" "HPA013331, CAB033884, HPA039262" Enhanced NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB033884: AB_2266773, HPA013331: AB_1854245, HPA039262: AB_2676418" "unprognostic (1.00e-2)" "unprognostic (7.99e-2)" "unprognostic (4.36e-3)" "unprognostic (2.31e-1)" "unprognostic (2.51e-1)" "unprognostic (1.28e-1)" "unprognostic (7.85e-2)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" 3.2 1.1 3.9 0.0 3.5 0.0 6.4 3.6 4.1 1.2 3.0 1.9 0.0 1.4 0.2 1.1 0.8 0.6 23165.6 3.3 4.1 1.0 2.3 21.8 0.8 3.6 3.8 4.3 18.4 0.4 9.7 2.2 3.6 2.0 0.0 0.2 11.6 0.3 3.0 2.3 2.0 0.0 3.3 0.9 1.3 1.0 4.4 0.0 3.5 0.0 0.0 0.4 1.9 3.3 0.0 0.0 0.0 0.0 0.0 0.0 35.6 0.0 0.0 0.4 0.0 124.6 0.0 0.0 1.6 0.0 0.0 0.6 0.0 0.1 0.5 0.0 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.9 0.4 0.0 47.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 3.5 3.6 4.1 3.3 4.1 3.6 3.8 3.6 3.3 4.4 3.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.4 30.5 10772.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 78.5 0.0 2.7 0.3 0.0 0.2 695.9 0.0 0.0 0.0 24.9 0.0 0.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 160.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46702282-46790407 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 103.4;skeletal muscle: 46.5;tongue: 72.6" "Group enriched" "Detected in some" 12 "Cardiomyocytes: 169.0;Endometrial ciliated cells: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 12.9;HEL: 40.2;K-562: 6.5;SK-BR-3: 7.9" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.6;hippocampal formation: 5.1" "Region enriched" "Detected in single" 5 "hippocampal formation: 3.5" HPA073447 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Vesicles "HPA073447: AB_2732225" "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 1.9 0.1 1.7 0.3 0.1 1.1 2.3 0.4 1.7 0.0 0.1 0.3 0.8 4.3 1.7 0.2 103.4 2.5 2.8 1.1 0.1 0.4 0.2 9.8 12.2 0.3 0.1 0.0 0.4 0.5 8.2 2.2 0.1 0.2 2.1 0.1 46.5 0.1 0.1 0.2 5.9 0.1 0.1 6.0 1.9 0.1 0.1 72.6 0.1 0.0 0.0 3.0 0.0 0.1 0.1 0.1 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 2.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 6.5 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 7.9 0.2 3.5 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 1.9 1.7 1.1 2.3 2.5 2.8 9.8 12.2 8.2 5.9 1.9 3.0 0.2 0.0 3.3 0.7 0.5 0.0 0.7 0.0 0.0 0.9 1.3 0.0 169.0 0.0 3.7 0.0 2.1 2.0 0.2 0.0 0.0 0.0 8.1 44.8 7.1 1.7 0.0 0.0 0.9 0.2 0.5 6.7 0.0 2.2 1.3 1.6 0.7 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 7.2 0.6 0.8 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.8 0.0 0.2 8.7 1.3 0.0 4.9 2.7 1.0 0.7 0.0 0.0 0.3 0.8 0.7 0.0 0.8 MYO18A "KIAA0216, MysPDZ" ENSG00000196535 "Myosin XVIIIA" Q92614 17 29071122-29180398 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 404.2;tongue: 124.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 33.6;Oligodendrocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 60.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019646 Supported NA NA 3400000 "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA019646: AB_1854249" "unprognostic (2.54e-2)" "unprognostic (1.08e-1)" "unprognostic (5.36e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-1)" "unprognostic (3.48e-1)" "unprognostic (1.72e-1)" "unprognostic (3.31e-2)" "unprognostic (8.70e-2)" "prognostic unfavorable (3.28e-4)" "unprognostic (1.94e-1)" "unprognostic (1.74e-1)" "prognostic favorable (3.18e-4)" "unprognostic (6.94e-2)" "unprognostic (2.12e-2)" "unprognostic (6.95e-3)" "unprognostic (1.95e-1)" 9.2 4.0 16.0 7.5 36.0 12.9 10.5 13.3 28.0 13.1 0.0 16.4 14.1 15.3 2.9 19.0 10.6 10.4 95.5 11.9 18.3 5.7 20.4 7.2 6.6 37.2 27.1 7.1 14.8 8.4 5.4 4.5 38.4 10.6 5.9 3.8 15.9 5.9 404.2 20.6 14.4 7.6 8.7 6.3 14.4 5.1 35.6 4.1 7.8 124.0 4.8 12.4 14.4 56.3 29.6 40.9 15.5 8.0 4.0 7.0 24.8 13.8 13.7 11.8 8.2 10.3 20.5 3.1 15.2 10.0 17.3 33.2 6.0 23.1 4.6 34.4 11.4 2.6 12.9 11.3 6.1 3.7 3.6 8.1 13.2 7.2 3.2 19.5 4.3 12.3 37.1 5.3 5.9 10.2 10.8 2.9 3.2 60.1 9.0 37.3 17.3 9.1 9.0 21.7 8.1 8.3 13.7 45.5 9.8 10.2 10.6 4.4 5.0 7.7 9.3 5.2 9.6 10.0 18.1 5.9 9.7 2.6 20.9 0.6 0.2 0.4 0.3 0.3 0.4 0.1 0.3 0.3 0.3 0.3 0.4 0.2 0.5 0.3 0.3 0.4 0.2 0.1 16.0 36.0 13.3 28.0 11.9 18.3 37.2 27.1 38.4 8.7 35.6 56.3 14.8 12.8 7.0 13.4 5.4 1.0 1.0 0.5 10.8 7.1 3.7 3.3 33.6 2.8 8.3 1.8 10.4 0.4 2.8 8.6 0.0 2.9 1.4 1.9 4.4 8.1 2.4 9.0 13.6 1.4 2.7 4.9 21.4 2.3 1.3 15.3 2.2 5.0 1.1 1.7 13.3 4.0 0.0 0.6 1.3 0.6 2.1 6.1 0.0 9.4 2.0 2.6 2.1 14.6 38.8 4.2 5.1 3.0 6.8 1.0 5.0 1.7 1.7 4.2 0.0 4.7 2.0 1.3 1.3 9.5 0.9 0.3 5.5 3.2 4.1 1.1 MYOM3 FLJ35961 ENSG00000142661 "Myomesin 3" Q5VTT5 1 24056035-24112135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 222.5;skeletal muscle: 321.5;tongue: 255.9" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 198.3" "Cancer enhanced" "Detected in some" "renal cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 4.6;Hep G2: 18.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028132, HPA028340" Approved "Golgi apparatus,Vesicles,Cytokinetic bridge" Yes No 830000 "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "Golgi apparatus, Cytokinetic bridge" "HPA028132: AB_10599293, HPA028340: " "unprognostic (8.59e-2)" "unprognostic (2.85e-2)" "unprognostic (2.39e-1)" "unprognostic (8.60e-3)" "unprognostic (1.52e-2)" "unprognostic (7.31e-2)" "unprognostic (3.00e-2)" "unprognostic (1.40e-2)" "unprognostic (4.66e-1)" "unprognostic (2.21e-1)" "unprognostic (2.73e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.28e-6)" "unprognostic (2.77e-2)" "unprognostic (1.60e-3)" "unprognostic (7.75e-2)" "unprognostic (1.68e-1)" 0.4 0.2 0.0 0.2 0.0 0.0 0.7 0.3 0.1 0.2 0.0 0.6 1.1 0.3 0.0 6.0 0.9 0.4 222.5 0.1 0.1 31.4 0.2 0.3 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.1 4.5 0.7 1.2 7.1 0.0 321.5 2.2 5.2 0.2 0.0 0.0 0.2 9.0 0.0 1.7 0.3 255.9 0.1 0.1 0.4 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 1.3 0.0 1.9 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.8 18.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.2 0.1 1.0 0.2 0.5 0.6 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.6 0.2 0.1 0.6 0.0 0.1 0.6 198.3 0.0 0.0 3.7 0.0 0.0 0.1 3.6 1.9 0.1 16.2 0.4 0.0 1.6 1.2 0.0 0.4 0.4 0.0 6.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.7 10.3 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.5 2.4 0.0 0.0 0.2 13.0 33.2 0.0 2.5 6.6 10.0 1.3 0.0 0.2 0.0 0.6 0.0 0.3 2.3 2.2 0.3 MYOZ2 "C4orf5, CS-1, FATZ-2" ENSG00000172399 "Myozenin 2" Q9NPC6 4 119135832-119187789 "Disease related genes, Predicted intracellular proteins" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 771.4;skeletal muscle: 225.5;tongue: 173.4" "Cell type enriched" "Detected in some" 51 "Cardiomyocytes: 2275.3" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.0;HSkMC: 2.3;SK-MEL-30: 6.2;U-87 MG: 6.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA035763, HPA035764" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "HPA035763: AB_2674770, HPA035764: AB_10696509" "unprognostic (2.53e-1)" "unprognostic (9.20e-2)" "unprognostic (6.94e-2)" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.34e-2)" "unprognostic (5.71e-1)" "unprognostic (2.18e-1)" "unprognostic (4.77e-2)" "unprognostic (4.04e-1)" "unprognostic (8.25e-2)" "unprognostic (5.07e-2)" "unprognostic (6.19e-7)" "unprognostic (6.66e-4)" "unprognostic (2.43e-1)" "unprognostic (3.06e-1)" "unprognostic (2.83e-2)" 0.6 0.3 0.2 0.0 0.3 0.0 2.1 0.1 0.5 0.7 0.0 1.0 0.0 2.0 0.3 1.0 1.0 0.3 771.4 0.2 0.3 0.7 0.1 0.9 0.3 0.2 0.2 0.6 0.1 0.0 0.2 0.2 0.1 4.8 0.1 0.0 1.8 0.3 225.5 0.5 0.4 0.8 0.2 0.6 0.6 1.0 0.3 0.3 0.3 173.4 0.1 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.3 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.2 1.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.5 0.2 0.3 0.2 0.2 0.1 0.2 0.3 0.2 0.1 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 2275.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 20.8 0.0 0.0 3.4 2.2 0.0 44.1 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.7 0.0 0.2 0.0 2.9 0.0 0.0 6.6 6.9 22.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.7;Distal tubular cells: 201.5;Ductal cells: 112.8;Exocrine glandular cells: 100.1;Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 47.1 74.8 61.0 20.9 63.7 22.2 47.9 66.1 69.6 56.8 71.1 62.9 45.5 68.8 88.7 58.0 59.5 26.5 111.1 60.9 64.3 83.8 86.5 43.6 27.0 62.7 64.8 46.5 69.7 104.7 70.0 23.7 61.8 62.5 41.6 17.4 53.9 48.3 71.8 55.8 48.3 39.7 64.7 43.2 67.5 40.8 63.5 30.6 59.8 68.2 34.3 55.0 47.8 70.5 114.2 155.4 43.9 84.4 64.0 43.8 55.5 29.5 62.3 69.5 72.6 130.6 76.8 62.4 113.4 52.5 55.9 111.1 49.4 99.0 47.5 81.2 98.5 58.1 76.2 86.1 75.1 60.0 60.9 44.2 123.7 87.9 81.9 53.4 95.4 104.7 54.7 70.1 71.6 209.6 83.3 98.0 43.1 158.1 118.2 87.7 40.2 212.6 93.0 93.6 114.7 102.9 90.4 172.4 141.6 66.4 178.3 117.5 51.1 45.1 64.8 64.6 70.6 180.1 110.3 53.0 63.1 37.0 70.4 25.4 96.3 52.9 121.2 111.3 121.3 236.2 109.4 124.3 89.1 186.5 122.8 114.9 11.4 141.3 89.1 225.7 110.1 186.6 61.0 63.7 66.1 69.6 60.9 64.3 62.7 64.8 61.8 64.7 63.5 70.5 29.5 41.7 32.9 0.0 14.8 0.0 0.0 0.0 0.0 0.0 87.5 96.0 0.0 0.0 23.5 68.0 0.0 136.7 28.7 0.0 201.5 112.8 0.0 27.3 29.9 18.4 0.0 0.0 0.0 100.1 43.1 27.2 0.0 32.0 5.1 53.5 0.0 0.0 92.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 91.0 0.0 0.0 6.2 0.0 0.0 219.6 11.7 0.0 0.0 0.0 24.5 0.0 0.0 0.0 0.0 81.3 13.4 48.1 0.0 0.0 NDRG2 "KIAA1248, SYLD" ENSG00000165795 "NDRG family member 2" Q9UN36 14 21016763-21070872 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1885.3;salivary gland: 2081.6;skeletal muscle: 1828.7" "Cell type enhanced" "Detected in many" "Astrocytes: 379.0;Distal tubular cells: 485.2;Muller glia cells: 548.0;Sertoli cells: 598.2" "Cancer enhanced" "Detected in all" "glioma: 78.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "myeloid DC: 204.4" "Lineage enriched" "Detected in all" 11 "dendritic cells: 204.4" "Cell line enhanced" "Detected in many" "Hep G2: 57.0;HMC-1: 39.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002896, HPA003590, CAB017491" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB017491: AB_2298331, HPA002896: AB_1079459, HPA003590: AB_1079458" "unprognostic (9.27e-3)" "unprognostic (2.97e-3)" "unprognostic (1.26e-2)" "unprognostic (5.09e-3)" "unprognostic (2.00e-2)" "unprognostic (2.92e-2)" "prognostic favorable (6.71e-4)" "unprognostic (1.85e-3)" "unprognostic (5.57e-2)" "unprognostic (3.46e-2)" "unprognostic (1.69e-1)" "unprognostic (5.10e-2)" "prognostic favorable (1.43e-12)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (4.19e-2)" 192.0 400.6 1613.1 27.4 1885.3 2.8 321.6 1623.2 1666.4 395.4 1189.8 198.3 72.1 229.7 260.3 229.5 305.0 130.7 327.2 1551.7 1590.0 150.1 544.4 115.5 48.6 1690.6 1686.1 476.1 93.7 278.5 88.5 45.3 1581.9 171.3 111.0 134.1 2081.6 208.0 1828.7 220.3 125.4 127.7 1584.5 152.0 130.9 33.3 1752.7 40.1 99.9 1591.4 100.4 158.0 265.8 1597.9 10.9 2.3 6.8 12.6 1.1 0.0 1.0 0.2 4.5 3.9 2.2 15.1 20.0 0.6 4.0 0.3 6.2 17.6 30.3 6.3 5.4 0.1 10.9 14.3 2.2 57.0 1.3 1.3 39.0 11.8 13.1 0.9 1.9 6.3 0.0 12.6 29.0 1.2 0.6 9.4 5.0 4.0 17.9 35.2 0.8 14.6 0.7 3.7 7.6 27.4 0.1 19.4 3.0 3.3 14.4 17.3 26.6 8.2 0.0 1.2 20.8 0.4 0.4 6.1 4.8 0.3 1.8 0.3 4.7 0.0 6.5 0.7 8.3 1.5 11.4 6.4 12.6 11.9 204.4 4.4 18.7 14.0 1.4 3.0 0.1 7.0 9.4 15.3 1613.1 1885.3 1623.2 1666.4 1551.7 1590.0 1690.6 1686.1 1581.9 1584.5 1752.7 1597.9 98.0 0.0 11.9 379.0 6.7 28.7 83.7 86.4 12.0 6.3 240.7 201.2 180.2 151.5 110.9 40.5 10.4 11.5 9.1 81.4 485.2 104.9 6.3 33.3 11.0 53.9 33.5 8.4 1.1 21.7 0.7 62.3 18.8 40.2 48.8 79.0 164.2 214.9 20.7 3.3 3.9 77.4 57.0 30.8 137.6 14.4 348.6 30.4 321.9 47.8 8.7 548.0 1.0 42.7 71.0 16.3 37.9 166.3 1.2 68.5 18.5 41.3 70.8 15.5 598.2 167.7 162.8 1.7 5.5 21.6 30.4 21.6 11.9 66.8 118.9 155.9 NDRG4 "KIAA1180, SMAP-8" ENSG00000103034 "NDRG family member 4" Q9ULP0 16 58462846-58513628 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 380.7;heart muscle: 352.7" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 433.0;Horizontal cells: 516.5" "Cancer enriched" "Detected in many" 6 "glioma: 23.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 32.5;GAMG: 28.6;hTERT-RPE1: 26.8;HUVEC TERT2: 21.0;SCLC-21H: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015313, HPA017587" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "HPA015313: AB_1854343, HPA017587: AB_1854344" "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" "unprognostic (9.03e-3)" "unprognostic (1.59e-2)" "unprognostic (3.97e-1)" "unprognostic (1.03e-1)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (6.07e-2)" "unprognostic (1.02e-1)" "unprognostic (4.84e-3)" "unprognostic (5.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.22e-2)" "unprognostic (8.51e-2)" "unprognostic (4.45e-2)" "unprognostic (7.17e-2)" 16.4 128.8 122.7 2.9 136.0 0.1 11.4 239.4 248.6 25.3 0.0 6.5 3.7 25.5 6.8 20.8 8.0 3.6 352.7 195.0 170.4 1.6 1.0 17.7 4.1 379.4 113.0 1.8 2.7 12.0 71.6 2.0 380.7 3.1 3.2 115.5 5.3 30.2 8.7 21.5 3.9 13.3 41.6 21.9 4.1 48.1 190.9 4.5 2.7 3.6 4.0 3.7 57.5 91.7 0.2 16.9 15.8 3.1 0.4 2.9 1.3 5.2 8.2 2.5 1.7 6.5 4.3 0.4 32.5 4.0 28.6 1.5 1.2 0.9 2.2 0.0 3.3 0.7 3.3 4.7 4.4 0.3 0.3 3.6 0.3 1.6 0.0 26.8 21.0 0.1 0.3 0.2 2.4 4.3 1.7 0.2 1.4 0.6 12.4 0.4 4.4 0.4 0.7 10.6 49.2 18.4 0.5 1.4 0.1 2.0 0.6 0.2 7.7 2.1 6.0 0.6 0.8 0.9 0.5 5.7 11.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.7 136.0 239.4 248.6 195.0 170.4 379.4 113.0 380.7 41.6 190.9 91.7 8.9 0.0 1.9 53.5 0.2 2.0 6.8 0.6 1.2 52.3 0.7 1.5 433.0 0.0 0.3 0.0 4.2 0.0 0.1 0.6 0.0 4.0 5.9 4.0 5.6 17.0 1.8 0.0 95.7 0.2 0.1 10.1 1.5 11.5 0.0 13.6 29.3 0.3 0.0 516.5 94.3 0.1 2.0 1.0 1.2 10.8 4.4 0.3 7.2 22.5 0.0 82.6 0.0 29.7 14.1 3.7 0.0 2.6 0.0 4.9 0.0 0.2 0.2 33.4 6.6 3.5 6.7 4.8 6.5 14.5 5.8 0.0 0.3 0.3 0.0 8.8 NDUFA13 "B16.6, CDA016, CGI-39, GRIM-19, GRIM19" ENSG00000186010 "NADH:ubiquinone oxidoreductase subunit A13" Q9P0J0 19 19515736-19529054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Electron transport, Host-virus interaction, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2947.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041213 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA041213: AB_10794988" "unprognostic (2.87e-1)" "unprognostic (2.88e-3)" "unprognostic (9.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "unprognostic (5.78e-2)" "unprognostic (6.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.81e-1)" "unprognostic (1.83e-3)" "unprognostic (1.26e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (1.33e-1)" "unprognostic (2.37e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-2)" 268.1 248.1 586.0 184.1 601.2 318.9 226.6 612.2 726.3 188.2 632.2 324.0 268.5 129.8 414.0 288.3 253.0 165.0 987.1 577.4 609.2 274.5 301.3 154.8 234.9 600.9 585.1 168.3 274.3 541.3 154.7 186.6 588.3 216.1 212.4 100.7 272.8 220.4 1093.2 183.1 245.1 193.5 593.6 160.6 251.2 208.5 624.2 254.5 221.2 1102.9 178.5 250.9 103.5 607.7 371.4 405.5 443.7 531.6 460.2 416.2 606.4 345.8 488.3 500.0 492.2 639.4 584.9 442.6 952.2 495.2 261.4 307.2 313.0 477.6 177.3 276.5 1052.6 308.9 590.9 834.1 448.0 601.1 517.0 546.5 483.7 322.7 335.5 296.3 382.8 533.1 428.6 728.2 400.3 1115.4 811.2 880.9 528.4 846.6 1004.4 536.0 263.0 830.2 711.1 782.6 508.9 633.2 350.0 551.7 481.1 225.2 367.7 1035.9 307.3 538.4 177.5 583.8 541.0 543.6 430.6 510.3 428.4 624.2 390.8 1210.3 1162.6 963.4 758.6 1263.4 678.0 1284.6 874.1 838.9 1165.9 1097.3 831.6 775.7 411.9 779.9 1054.3 979.4 1246.2 2090.8 586.0 601.2 612.2 726.3 577.4 609.2 600.9 585.1 588.3 593.6 624.2 607.7 155.1 131.4 184.8 33.0 194.5 129.0 75.9 346.9 117.8 64.8 211.3 181.2 514.5 224.4 251.2 250.1 25.0 426.6 136.6 951.6 610.5 566.0 411.8 154.5 111.5 131.4 556.3 185.3 22.7 578.5 357.2 173.1 225.3 130.5 259.3 51.3 182.4 422.6 333.6 42.1 27.2 719.7 268.5 307.4 197.9 2947.1 153.4 198.3 263.3 19.7 456.7 186.3 183.4 17.6 41.2 490.5 931.9 129.1 272.0 75.0 1114.7 772.0 236.5 84.2 92.1 91.6 196.2 80.6 111.5 210.0 127.0 498.4 177.5 48.0 683.0 87.4 NDUFA2 B8 ENSG00000131495 "NADH:ubiquinone oxidoreductase subunit A2" O43678 5 140638740-140647771 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1052.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035933 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA035933: AB_10669661" "unprognostic (4.48e-1)" "prognostic favorable (6.53e-4)" "unprognostic (3.61e-2)" "unprognostic (1.96e-2)" "unprognostic (6.15e-2)" "unprognostic (5.39e-3)" "unprognostic (4.01e-1)" "unprognostic (2.75e-2)" "unprognostic (1.60e-1)" "unprognostic (4.39e-3)" "unprognostic (1.84e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.78e-2)" "unprognostic (9.96e-2)" "unprognostic (4.22e-1)" "unprognostic (1.30e-3)" 76.1 127.9 131.0 52.3 131.3 96.0 67.3 139.0 156.1 49.2 139.8 81.0 90.2 43.8 79.0 73.5 50.3 45.8 197.3 129.8 137.1 144.9 145.1 53.3 66.1 133.3 131.0 54.9 81.5 99.8 79.1 47.3 133.3 68.7 60.9 51.8 102.2 46.8 283.8 52.4 86.1 31.6 135.8 72.6 90.8 79.7 134.9 78.1 64.2 233.0 48.2 55.5 51.3 142.3 131.1 202.5 91.3 195.9 113.6 84.5 117.8 76.6 69.0 99.4 120.4 328.1 149.5 125.4 191.2 65.9 122.9 103.7 88.4 153.9 57.1 120.6 226.6 80.1 170.6 248.3 67.7 138.7 102.6 100.6 116.6 65.4 47.5 84.3 101.2 111.8 86.9 194.4 93.1 204.9 168.4 285.9 97.5 152.8 203.6 144.7 110.4 212.7 167.5 146.4 119.6 99.4 104.7 292.2 221.8 81.9 269.7 216.3 70.1 113.9 84.8 96.3 125.9 214.2 339.4 190.1 132.3 152.8 65.0 195.0 304.6 311.5 133.1 270.1 137.4 222.0 141.1 143.0 258.1 178.0 127.0 135.6 255.8 156.8 219.9 273.3 205.6 322.8 131.0 131.3 139.0 156.1 129.8 137.1 133.3 131.0 133.3 135.8 134.9 142.3 138.4 109.0 125.4 10.4 127.5 97.8 116.4 311.1 105.3 87.4 182.2 203.5 314.4 200.1 199.7 244.6 37.5 294.1 168.0 499.6 815.9 187.8 526.6 194.5 114.1 115.8 193.2 222.2 6.5 220.4 231.0 115.9 122.9 171.9 92.5 121.2 169.6 516.1 291.9 53.8 7.7 337.9 258.4 251.3 144.6 435.1 165.0 168.0 190.3 5.6 265.1 227.3 211.2 5.5 12.9 194.7 474.4 153.4 151.8 153.8 682.9 1052.3 207.9 113.0 118.3 104.8 139.0 182.7 237.0 165.8 117.1 222.5 124.3 196.1 367.5 164.4 NDUFA3 B9 ENSG00000170906 "NADH:ubiquinone oxidoreductase subunit A3" O95167 19 54102728-54109257 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 625.9;skeletal muscle: 492.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1133.8;Late spermatids: 2033.9;Proximal tubular cells: 1213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 74.0" "Low region specificity" "Detected in all" HPA046976 Supported NA NA "Cluster 11: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA046976: AB_10960994" "unprognostic (3.04e-2)" "unprognostic (4.12e-3)" "unprognostic (9.53e-2)" "unprognostic (5.95e-2)" "unprognostic (6.73e-2)" "unprognostic (3.14e-2)" "unprognostic (3.91e-1)" "unprognostic (3.05e-1)" "unprognostic (2.95e-1)" "unprognostic (2.00e-2)" "prognostic favorable (9.65e-4)" "unprognostic (9.91e-2)" "unprognostic (3.24e-3)" "unprognostic (7.79e-2)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" "prognostic favorable (4.80e-4)" 134.4 192.6 20.7 3.2 21.1 6.5 108.0 27.2 28.0 96.2 23.5 142.8 11.2 102.6 5.2 127.7 95.8 5.4 625.9 21.3 21.4 259.5 248.2 102.5 5.1 22.3 20.2 104.5 124.0 4.8 225.9 3.3 21.4 122.5 8.1 6.5 113.4 3.7 492.4 84.8 117.6 4.0 17.3 133.5 160.7 164.3 24.3 3.5 152.4 10.8 5.4 97.6 92.3 26.6 9.1 9.7 8.4 11.6 10.3 10.7 5.2 7.6 9.3 6.5 7.3 10.1 7.2 8.2 5.3 7.4 6.1 6.6 6.9 16.7 3.5 11.5 32.0 9.5 9.6 11.9 7.6 9.2 2.3 6.2 15.1 5.2 8.5 3.1 11.7 7.3 4.9 3.5 6.9 32.3 7.3 10.5 7.4 74.0 15.2 4.3 5.0 17.7 4.9 23.2 14.1 6.9 6.9 17.7 4.3 10.3 23.4 9.6 8.7 7.4 4.5 4.0 13.2 6.9 5.7 3.9 9.1 10.5 4.5 25.2 12.9 20.9 12.6 15.3 13.0 18.4 13.0 12.9 14.3 16.1 13.5 13.6 12.5 18.0 12.3 23.7 14.5 22.3 20.7 21.1 27.2 28.0 21.3 21.4 22.3 20.2 21.4 17.3 24.3 26.6 146.9 96.1 117.4 4.6 168.1 39.8 53.5 266.5 58.6 37.7 196.2 212.6 1133.8 203.0 171.4 393.6 10.4 164.1 158.3 544.0 815.9 183.6 497.6 239.6 124.9 118.2 300.5 169.0 5.2 192.5 171.9 122.9 174.8 180.2 116.5 138.3 194.9 527.7 306.9 23.5 6.4 380.2 209.5 267.4 114.4 2033.9 163.1 181.6 218.7 1.9 300.4 146.3 265.7 3.0 7.7 204.2 448.8 141.4 232.7 67.5 705.7 1213.0 225.1 71.0 85.5 62.5 125.8 215.3 69.8 122.6 62.5 148.4 168.6 75.3 404.2 66.6 NDUFA5 "B13, CI-13kB, CI-13KD-B, NUFM, UQOR13" ENSG00000128609 "NADH:ubiquinone oxidoreductase subunit A5" Q16718 7 123536997-123557904 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 403.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 717.3;Distal tubular cells: 1070.2;Proximal tubular cells: 667.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043175 Supported NA NA 81000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043175: AB_10793992" "prognostic favorable (8.47e-5)" "unprognostic (4.00e-2)" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "unprognostic (4.90e-2)" "unprognostic (3.26e-1)" "unprognostic (2.23e-1)" "unprognostic (3.46e-2)" "unprognostic (1.81e-1)" "unprognostic (2.14e-2)" "unprognostic (1.37e-1)" "unprognostic (9.20e-2)" "prognostic favorable (3.99e-9)" "unprognostic (3.39e-1)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (2.73e-3)" 55.2 129.2 94.7 34.1 99.9 34.8 68.8 94.2 130.1 51.3 93.4 78.5 77.6 47.5 71.5 51.0 51.8 47.0 215.7 100.5 108.4 175.3 114.9 44.4 40.0 92.4 97.6 42.2 41.2 170.1 58.3 39.7 98.5 72.8 73.3 127.1 75.6 63.1 285.1 27.2 72.7 46.9 92.6 35.4 77.4 38.3 94.4 52.8 136.6 403.3 42.5 57.8 33.5 91.6 65.9 41.8 76.3 76.6 64.5 58.6 39.5 57.4 63.1 46.8 61.1 47.1 58.2 108.6 54.8 58.8 91.0 60.7 83.9 75.2 74.3 89.6 71.7 68.8 85.9 78.1 62.7 140.5 56.4 58.6 65.9 45.3 47.3 84.1 68.4 75.4 213.9 104.9 84.4 45.5 127.3 162.1 100.3 154.3 107.0 69.2 75.0 146.6 129.5 63.7 144.9 86.3 76.1 286.2 90.3 102.5 65.6 104.7 53.1 58.9 31.7 262.0 88.5 111.2 109.4 116.4 112.7 106.2 75.7 57.8 26.2 31.5 38.2 48.7 55.4 53.6 48.6 44.9 37.1 41.6 52.5 54.0 9.2 52.7 54.8 40.0 55.8 60.4 94.7 99.9 94.2 130.1 100.5 108.4 92.4 97.6 98.5 92.6 94.4 91.6 99.2 102.5 100.4 38.2 108.7 112.5 146.2 280.3 74.6 183.6 113.0 100.8 717.3 102.9 160.6 165.5 83.4 160.6 105.6 119.0 1070.2 132.2 359.6 123.4 91.1 91.8 138.0 91.1 65.2 89.6 156.8 110.5 108.6 128.6 88.7 59.2 66.0 170.6 109.6 127.9 48.5 168.6 295.0 67.2 92.5 77.5 90.1 94.9 202.7 19.7 65.7 264.6 77.2 32.2 29.2 86.2 130.9 112.1 82.0 107.1 210.2 667.6 158.6 214.7 118.3 97.4 133.7 179.0 99.0 94.7 110.2 158.4 102.3 116.9 172.2 147.0 NDUFA6 "B14, CI-B14, LYRM6, NADHB14" ENSG00000184983 "NADH:ubiquinone oxidoreductase subunit A6" P56556 22 42085526-42090884 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1536.8;Distal tubular cells: 954.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 181.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (3.48e-2)" "prognostic favorable (3.87e-4)" "unprognostic (7.00e-3)" "prognostic favorable (4.96e-4)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (4.02e-2)" "unprognostic (2.71e-2)" "unprognostic (1.47e-2)" "unprognostic (8.28e-2)" "unprognostic (3.61e-1)" "prognostic favorable (1.05e-6)" "unprognostic (2.15e-1)" "unprognostic (1.63e-1)" "unprognostic (9.49e-2)" "unprognostic (4.84e-2)" 9.8 30.9 14.3 19.2 13.1 25.9 28.0 13.9 18.9 9.6 19.1 37.6 12.5 15.7 21.3 38.5 8.8 10.9 124.2 13.4 15.0 37.3 51.4 15.4 20.6 14.9 13.7 9.3 31.2 109.2 17.8 25.2 16.1 17.8 57.6 19.8 28.2 18.8 115.1 12.4 38.1 14.2 12.9 18.0 30.7 22.2 15.0 3.7 20.3 101.5 11.9 24.0 9.3 13.1 48.1 1.9 4.5 44.2 94.6 78.9 6.3 0.3 0.3 0.8 1.0 54.1 99.2 0.7 1.4 67.4 2.3 47.9 1.2 1.2 4.5 0.4 0.7 1.0 10.2 181.7 0.9 55.3 73.1 28.1 27.7 57.0 102.2 1.6 33.9 2.0 73.9 94.1 1.6 90.8 35.6 3.7 34.5 134.6 138.7 60.2 48.6 0.3 1.3 6.0 1.0 31.8 96.4 56.5 143.4 6.0 113.2 0.6 0.0 2.3 110.2 41.9 72.6 41.5 64.0 4.5 35.8 95.8 98.9 127.4 109.8 123.4 78.2 114.0 84.8 111.8 106.0 72.9 156.5 85.3 88.4 88.2 37.7 98.6 99.4 99.3 109.0 213.5 14.3 13.1 13.9 18.9 13.4 15.0 14.9 13.7 16.1 12.9 15.0 13.1 103.3 60.9 94.1 15.7 103.8 185.7 228.5 445.8 76.8 58.7 105.7 132.8 1536.8 164.5 189.2 180.3 45.9 422.1 105.6 349.0 954.8 267.3 181.3 104.0 99.6 123.3 170.8 140.8 9.7 253.9 443.7 152.2 114.7 106.6 105.2 70.1 94.2 598.6 357.9 35.3 13.4 293.3 386.6 114.6 255.4 52.0 100.9 145.8 288.1 5.6 198.0 129.4 117.4 5.0 9.3 260.5 361.8 110.6 166.7 202.6 517.5 597.8 131.4 99.7 105.2 98.9 329.1 142.5 163.8 159.9 186.0 764.1 123.8 117.7 301.9 230.4 NDUFA7 B14.5a ENSG00000267855 "NADH:ubiquinone oxidoreductase subunit A7" O95182 19 8308768-8321375 "Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 245.6" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 167.5;Proximal enterocytes: 183.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA059251, HPA071866" Enhanced Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA059251: AB_2683960, HPA071866: AB_2686465" "unprognostic (6.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (3.85e-1)" "unprognostic (2.18e-1)" "unprognostic (5.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.43e-2)" "unprognostic (3.40e-1)" "unprognostic (1.13e-3)" "unprognostic (1.81e-2)" "unprognostic (1.43e-1)" "unprognostic (1.09e-2)" "unprognostic (5.53e-2)" "unprognostic (1.29e-2)" "unprognostic (2.59e-2)" "unprognostic (9.35e-3)" 39.4 87.5 86.2 19.8 90.0 34.2 33.1 89.8 96.1 21.3 95.9 46.6 24.2 27.7 53.5 57.6 42.3 25.1 168.1 87.6 90.0 88.3 83.4 31.0 29.6 87.1 88.1 25.1 37.1 103.7 86.4 23.4 87.3 41.2 33.5 32.3 43.5 20.7 245.6 30.7 34.0 22.8 87.3 42.0 54.7 18.7 89.1 40.8 41.3 244.7 32.2 35.5 28.2 87.7 78.9 62.8 64.7 43.3 42.6 32.3 44.2 16.5 18.0 56.0 44.1 57.7 59.7 36.1 25.1 42.6 35.0 65.1 29.0 97.4 33.8 88.3 173.6 26.6 90.1 157.7 63.9 45.8 45.1 43.3 61.7 25.2 39.1 57.1 72.3 141.2 57.0 217.7 80.6 89.4 93.5 236.1 65.1 119.9 187.7 52.2 13.7 99.0 117.6 40.8 65.9 50.5 19.0 90.6 58.5 40.1 33.0 74.8 26.4 42.5 34.0 61.6 60.1 79.2 58.0 49.9 67.8 80.2 77.3 61.9 104.5 80.2 62.1 124.6 65.4 83.3 66.7 58.2 130.5 81.6 66.0 61.6 30.5 81.8 117.6 186.1 95.3 82.6 86.2 90.0 89.8 96.1 87.6 90.0 87.1 88.1 87.3 87.3 89.1 87.7 19.5 44.8 68.4 10.1 28.4 0.0 10.3 0.0 21.1 14.9 51.6 38.1 0.0 44.3 20.4 53.3 6.2 62.0 32.6 57.6 99.7 147.3 38.9 36.1 10.5 19.8 87.4 44.2 9.5 157.2 45.4 15.0 28.1 19.4 21.5 8.4 27.5 64.0 52.8 8.4 13.3 101.6 0.0 42.7 0.0 17.7 13.4 30.4 0.0 10.3 122.5 27.9 45.3 9.5 13.2 167.5 110.2 13.2 61.6 14.7 183.8 97.6 70.7 17.1 6.6 7.3 19.6 24.8 27.5 53.3 0.0 46.9 20.9 11.7 107.6 12.1 NDUFAF1 "CGI-65, CIA30" ENSG00000137806 "NADH:ubiquinone oxidoreductase complex assembly factor 1" Q9Y375 15 41387218-41409403 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 85.3;Spermatocytes: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039933, HPA040064" Supported Approved Mitochondria,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Mitochondria, Cytosol" "HPA039933: AB_10795265, HPA040064: AB_10795687" "unprognostic (2.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.72e-1)" "unprognostic (2.10e-3)" "unprognostic (2.38e-1)" "unprognostic (1.20e-1)" "prognostic favorable (2.88e-5)" "unprognostic (3.01e-1)" "unprognostic (2.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "prognostic favorable (3.34e-6)" "unprognostic (1.68e-1)" "unprognostic (3.23e-1)" "unprognostic (3.17e-2)" "unprognostic (2.05e-1)" 16.0 33.4 20.0 9.5 20.7 4.2 12.4 21.6 29.6 9.7 22.8 12.7 12.6 10.5 15.5 13.8 9.8 7.7 42.7 20.7 21.4 29.0 38.7 9.3 11.5 21.1 21.0 9.7 11.8 18.3 11.5 8.0 21.3 10.1 10.4 12.4 12.2 13.2 63.5 9.7 10.9 10.8 21.5 11.9 14.1 21.1 20.8 10.9 10.5 60.9 13.1 12.8 9.9 22.9 15.9 13.3 16.4 13.3 30.0 28.3 14.9 26.1 25.1 23.6 21.3 22.5 8.1 16.7 38.2 24.9 17.5 25.0 20.1 15.9 19.3 32.9 23.9 22.4 25.0 13.8 27.1 24.7 17.0 30.0 18.5 20.8 18.0 19.9 19.0 31.9 38.2 17.2 30.6 17.5 19.9 28.6 12.6 27.5 17.9 15.0 17.4 40.6 41.9 27.8 17.5 13.8 13.2 31.8 12.6 16.9 25.1 50.2 15.4 18.0 10.1 30.5 24.2 15.8 34.7 28.0 24.0 43.5 19.3 35.0 12.8 16.2 7.8 15.0 9.1 13.8 9.6 9.5 11.8 11.8 10.6 8.6 9.4 13.4 13.3 18.2 16.8 8.5 20.0 20.7 21.6 29.6 20.7 21.4 21.1 21.0 21.3 21.5 20.8 22.9 7.7 12.8 10.1 6.5 14.6 4.7 15.8 43.8 9.6 15.7 12.3 11.9 58.7 15.7 27.3 22.0 12.5 36.3 19.8 8.5 64.6 30.5 59.5 14.2 14.2 11.1 6.7 13.5 8.8 31.3 34.6 12.5 12.2 13.1 7.0 16.3 8.6 28.2 28.8 6.7 9.1 8.5 30.5 12.8 7.0 15.0 16.4 16.2 10.6 3.7 23.4 20.7 16.5 4.0 10.3 20.9 3.7 16.1 15.0 11.8 23.3 85.3 30.6 19.2 26.3 15.3 17.3 84.7 21.6 11.3 7.7 50.3 12.3 32.6 11.9 16.3 NDUFAF3 "2P1, C3orf60, DKFZP564J0123, E3-3, MGC10527" ENSG00000178057 "NADH:ubiquinone oxidoreductase complex assembly factor 3" Q9BU61 3 49020459-49023495 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 329.8" "Group enriched" "Detected in all" 4 "Distal tubular cells: 475.4;Early spermatids: 1124.6;Late spermatids: 1303.4;Proximal tubular cells: 658.1;Spermatocytes: 913.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035376, HPA035377" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA035376: AB_2674597, HPA035377: AB_10673219" "unprognostic (2.90e-2)" "unprognostic (2.72e-2)" "unprognostic (6.88e-2)" "unprognostic (3.03e-2)" "unprognostic (3.57e-2)" "unprognostic (2.61e-1)" "unprognostic (6.28e-3)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.64e-2)" "unprognostic (8.62e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.86e-5)" "unprognostic (7.97e-2)" "unprognostic (1.73e-1)" "unprognostic (8.02e-2)" "unprognostic (1.60e-1)" 69.0 121.9 112.1 36.4 119.9 51.7 60.7 124.3 123.6 58.4 117.3 43.5 34.9 58.6 47.7 48.5 61.7 32.3 166.0 109.4 117.8 88.6 85.2 52.2 45.3 121.2 116.5 59.4 48.8 84.1 99.0 29.9 120.2 57.2 27.0 26.2 70.7 51.5 127.0 33.1 41.4 30.7 120.5 53.9 49.8 329.8 118.0 52.0 71.2 99.6 37.7 51.1 45.7 126.8 47.7 68.4 60.6 59.9 78.5 66.6 35.0 59.6 57.5 82.8 64.5 98.9 75.1 55.1 68.5 92.1 113.4 34.9 43.3 95.4 29.6 72.9 76.8 109.5 129.9 124.8 110.4 92.2 50.8 68.5 72.5 116.6 85.8 98.9 73.0 169.4 31.4 136.0 90.8 73.9 134.1 46.5 20.1 78.1 183.0 41.1 24.3 169.3 136.7 97.4 52.9 61.6 55.0 115.1 59.1 27.3 66.5 177.6 64.4 76.4 52.0 108.0 100.1 110.8 79.3 86.6 93.2 48.4 121.8 144.3 164.6 143.9 157.6 175.3 168.4 244.1 172.6 160.6 144.9 234.0 223.3 170.2 51.8 154.9 201.2 297.8 180.5 250.4 112.1 119.9 124.3 123.6 109.4 117.8 121.2 116.5 120.2 120.5 118.0 126.8 117.4 93.0 95.2 7.2 95.3 53.3 143.7 113.6 66.0 60.4 119.4 125.5 198.0 104.4 109.6 150.8 2.1 135.2 81.9 124.6 475.4 171.7 1124.6 123.4 81.8 104.3 132.0 118.2 7.2 155.7 128.0 121.2 50.0 58.2 117.3 73.1 114.9 150.6 217.8 69.0 8.3 118.1 103.7 114.1 73.8 1303.4 170.2 129.5 136.9 11.2 149.6 171.5 103.0 6.6 19.6 139.5 148.0 120.7 151.1 175.5 176.9 658.1 199.2 52.8 72.3 87.5 106.4 913.0 88.6 108.4 54.8 106.9 91.2 105.6 109.4 154.9 NDUFAF5 "C20orf7, dJ842G6.1" ENSG00000101247 "NADH:ubiquinone oxidoreductase complex assembly factor 5" Q5TEU4 20 13785007-13821580 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Oxidoreductase, Transferase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 20.5" "Cell type enhanced" "Detected in many" "Early spermatids: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051184 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA051184: AB_2681377" "unprognostic (3.81e-1)" "unprognostic (1.27e-2)" "unprognostic (4.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (8.22e-2)" "unprognostic (1.68e-2)" "unprognostic (3.14e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (1.74e-3)" "unprognostic (2.41e-2)" "prognostic favorable (2.27e-6)" "unprognostic (5.38e-2)" "unprognostic (5.89e-2)" "unprognostic (6.88e-2)" "unprognostic (1.58e-2)" 3.2 3.8 4.3 1.2 4.2 5.9 3.0 4.8 5.0 2.8 4.1 5.1 3.6 3.2 0.9 3.1 2.7 1.5 10.4 4.2 4.0 5.0 4.8 2.6 1.5 3.8 3.7 2.2 2.5 4.4 3.4 2.1 4.0 3.3 2.6 3.7 2.9 1.9 20.5 3.4 3.1 3.0 3.5 2.4 3.6 3.9 4.3 2.7 2.4 17.1 1.7 3.3 3.0 4.3 6.5 6.3 7.4 5.1 5.7 1.7 3.7 4.6 3.6 6.0 5.0 13.8 4.7 10.8 4.6 4.9 11.3 8.6 13.9 9.1 4.9 5.1 8.0 9.6 3.9 16.8 7.3 8.6 4.7 3.4 6.4 7.3 4.8 2.6 5.2 10.2 7.6 5.2 5.9 8.4 12.3 7.8 2.6 7.3 6.7 8.1 9.1 6.6 6.8 8.5 7.4 7.5 5.0 13.5 15.0 2.4 6.8 6.0 5.6 7.1 3.6 6.0 7.4 5.7 9.2 8.7 3.1 3.6 7.4 1.2 2.1 4.0 2.4 2.7 1.7 2.5 2.0 1.6 3.0 2.2 2.3 2.3 0.5 3.5 1.9 3.6 2.4 1.1 4.3 4.2 4.8 5.0 4.2 4.0 3.8 3.7 4.0 3.5 4.3 4.3 9.0 0.0 11.2 18.3 8.3 6.2 8.6 15.1 6.8 46.6 6.5 10.4 42.4 4.3 7.4 11.0 27.1 15.9 12.4 8.6 29.4 12.1 68.2 6.5 8.8 8.7 12.5 3.4 27.0 5.6 8.4 10.5 13.3 7.3 7.6 15.9 3.9 11.4 14.0 11.8 29.3 14.1 22.4 8.8 5.9 12.7 6.8 7.7 1.8 12.2 7.9 13.9 13.4 20.6 19.3 9.8 6.2 12.4 8.8 8.9 12.8 33.1 7.4 25.0 0.0 8.8 18.0 35.9 26.7 9.9 7.4 14.6 10.7 18.5 11.7 12.9 NDUFAF6 "C8orf38, MGC40214" ENSG00000156170 "NADH:ubiquinone oxidoreductase complex assembly factor 6" Q330K2 8 94895767-95116455 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047148, HPA050545" Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA047148: AB_2679954, HPA050545: AB_2681166" "unprognostic (1.97e-3)" "unprognostic (1.62e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (8.73e-2)" "unprognostic (3.45e-2)" "unprognostic (7.62e-3)" "unprognostic (2.52e-2)" "unprognostic (9.61e-2)" "unprognostic (3.85e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-3)" "unprognostic (9.44e-2)" "unprognostic (1.57e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-3)" 4.7 3.1 6.9 4.1 7.7 5.5 5.3 8.8 8.1 1.9 5.1 4.4 2.1 3.2 5.7 4.3 4.2 1.9 8.8 6.4 7.8 4.4 10.9 2.6 4.9 6.9 7.6 3.9 3.1 3.5 2.6 3.6 7.3 3.5 5.5 7.4 2.2 3.4 14.6 5.6 3.0 3.2 6.7 3.1 4.3 4.0 7.6 4.7 6.3 13.8 5.2 2.5 1.7 8.9 7.7 4.5 5.4 5.1 3.5 4.3 11.1 8.0 5.0 6.6 4.8 3.6 3.7 14.8 5.3 3.7 2.0 6.3 7.8 5.4 4.9 3.7 15.1 13.7 10.0 6.7 5.4 5.1 6.9 6.5 9.0 3.8 6.1 3.0 3.8 12.1 9.9 8.0 8.0 6.8 13.0 16.5 5.9 10.0 10.6 8.6 4.3 11.3 6.1 7.3 10.1 5.5 4.1 2.5 10.8 6.5 10.1 4.2 4.8 4.7 3.7 3.7 5.8 10.7 8.5 12.4 3.9 13.5 2.7 1.9 1.8 3.0 2.3 1.1 2.9 5.8 3.2 2.2 2.4 5.4 3.1 2.3 0.9 2.9 2.2 2.1 2.9 1.9 6.9 7.7 8.8 8.1 6.4 7.8 6.9 7.6 7.3 6.7 7.6 8.9 23.4 12.8 15.9 35.3 23.6 9.7 10.1 21.5 19.4 22.7 25.7 27.4 32.0 28.6 21.2 12.9 16.7 24.0 14.3 18.5 43.0 15.8 28.5 13.5 9.1 14.8 12.5 23.3 31.8 34.7 30.2 9.4 10.7 9.8 31.8 21.5 12.1 28.3 22.6 25.2 37.0 15.3 24.4 7.3 5.6 8.1 10.5 10.1 14.2 33.7 12.0 25.6 6.2 43.2 58.3 19.3 18.2 13.9 53.1 11.2 23.2 38.2 24.7 23.6 13.1 11.9 21.4 28.4 43.9 17.9 11.9 10.9 13.0 16.5 19.4 9.5 NDUFB1 "CI-MNLL, MNLL" ENSG00000183648 "NADH:ubiquinone oxidoreductase subunit B1" O75438 14 92116122-92121917 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2435.4;Hepatocytes: 1690.0;Proximal tubular cells: 1614.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063737 Supported Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "Nuclear speckles" "HPA063737: AB_2685109" "unprognostic (1.12e-2)" "unprognostic (1.31e-3)" "unprognostic (6.70e-2)" "unprognostic (2.67e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-2)" "unprognostic (6.91e-2)" "unprognostic (3.74e-3)" "unprognostic (5.35e-3)" "unprognostic (4.55e-3)" "unprognostic (1.18e-2)" "unprognostic (4.15e-2)" "prognostic favorable (1.31e-5)" "unprognostic (7.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.05e-3)" 260.8 396.4 370.4 109.0 381.4 167.4 231.8 388.5 588.6 178.3 409.2 313.4 165.7 164.9 178.3 281.5 177.1 61.2 1221.5 381.0 401.1 512.7 503.2 182.3 118.4 379.8 374.6 162.7 206.3 373.5 314.7 61.1 383.2 221.5 122.4 260.9 233.5 59.5 862.6 153.6 225.9 69.4 381.2 214.0 292.4 112.3 376.4 230.6 250.4 1053.8 106.1 192.1 202.4 391.0 198.3 388.3 332.5 208.4 219.1 160.7 143.0 243.2 143.7 147.5 135.4 236.9 341.0 187.0 215.7 151.3 205.8 249.6 198.4 212.3 133.9 280.8 425.1 361.3 665.8 308.5 178.2 290.4 196.4 202.5 132.0 159.5 140.7 334.8 136.7 353.7 199.0 370.1 211.8 759.0 286.6 250.0 166.4 779.6 492.1 253.3 309.7 274.2 397.7 491.3 210.8 152.8 486.6 289.7 338.3 277.7 432.0 435.0 291.8 89.3 173.0 181.3 161.7 288.4 477.2 422.0 278.4 208.5 187.9 456.1 566.8 447.5 247.4 409.6 288.5 373.7 361.5 286.0 508.6 306.8 355.4 343.9 721.3 296.6 386.6 604.6 438.9 653.6 370.4 381.4 388.5 588.6 381.0 401.1 379.8 374.6 383.2 381.2 376.4 391.0 158.5 166.7 227.4 11.4 187.4 128.7 102.1 334.5 96.8 84.6 328.2 353.6 2435.4 467.5 237.0 389.9 39.6 260.3 170.4 627.2 1166.1 245.4 175.8 326.0 208.6 188.2 317.4 256.1 18.4 427.7 118.8 203.6 189.6 225.8 215.8 96.2 397.3 1690.0 422.3 55.5 21.7 515.9 268.5 619.8 179.3 57.3 262.5 281.7 332.6 10.3 478.1 223.3 241.0 11.1 15.0 294.4 628.7 241.1 201.6 97.9 845.2 1614.3 337.6 183.3 223.5 172.4 188.2 138.8 151.5 204.5 176.2 205.8 163.7 97.4 540.6 116.3 NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142216-47145038 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 717.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030367: AB_10603882" "unprognostic (2.20e-1)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (8.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (3.27e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (8.46e-3)" 71.1 133.8 136.0 73.2 141.2 133.2 89.8 147.7 170.6 74.6 158.5 112.5 96.7 54.4 104.6 95.2 84.1 46.2 251.4 140.3 142.3 108.9 164.4 62.2 90.3 144.7 139.0 58.5 158.2 122.9 92.7 62.4 142.0 73.9 98.2 59.2 128.2 79.2 717.0 76.1 96.1 72.2 138.3 74.5 97.8 26.8 146.3 97.8 95.6 378.4 106.3 68.0 66.5 139.3 173.5 297.9 198.7 242.4 173.6 166.1 221.1 125.2 180.5 231.5 224.4 292.6 224.2 218.5 101.8 163.4 222.3 216.2 267.0 157.3 162.0 212.4 663.1 129.5 371.2 271.3 184.7 203.2 188.2 176.9 140.0 191.2 126.8 137.8 193.9 286.8 158.6 282.6 139.3 437.2 269.1 622.5 308.5 219.2 517.2 259.7 210.9 513.6 254.0 210.1 391.2 283.1 231.9 289.2 198.8 259.8 418.2 279.7 130.3 152.7 190.5 239.1 149.0 244.0 270.0 258.5 155.0 138.4 204.2 255.4 410.3 188.6 294.2 306.5 362.1 541.7 408.9 342.6 491.6 470.0 454.3 359.3 84.9 279.7 233.8 636.5 476.3 626.1 136.0 141.2 147.7 170.6 140.3 142.3 144.7 139.0 142.0 138.3 146.3 139.3 154.0 105.8 132.5 16.6 270.9 259.5 252.1 514.5 267.5 89.2 343.7 520.1 236.6 265.9 284.7 290.6 37.5 456.9 227.6 400.0 583.0 314.9 5.2 193.4 229.7 165.6 330.7 246.3 10.2 369.1 429.2 192.1 200.8 267.1 194.1 219.2 203.8 657.2 391.0 55.5 16.7 495.1 333.7 321.7 290.9 16.3 181.7 229.1 265.1 12.2 336.9 238.9 183.4 14.1 25.3 291.8 391.2 176.4 445.1 258.6 360.1 756.8 180.9 109.8 164.3 157.6 248.9 16.8 36.9 358.0 290.5 450.9 228.9 342.6 447.4 334.9 NDUFB2 "AGGG, CI-AGGG" ENSG00000090266 "NADH:ubiquinone oxidoreductase subunit B2" O95178 7 140690777-140722790 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3191.4;Distal tubular cells: 1997.6;Proximal tubular cells: 2437.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051377 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Mitochondria "HPA051377: AB_2681460" "unprognostic (1.17e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-1)" "unprognostic (4.83e-2)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.20e-2)" "unprognostic (3.30e-2)" "unprognostic (8.30e-2)" "unprognostic (1.95e-3)" "unprognostic (4.35e-3)" "unprognostic (1.23e-1)" "prognostic favorable (7.60e-7)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" 187.2 225.3 347.4 123.4 363.9 143.1 159.9 377.3 441.6 142.0 374.0 239.9 166.0 153.4 171.5 196.9 129.6 141.8 847.4 343.6 369.1 420.0 281.2 140.1 164.8 359.0 355.8 108.0 159.4 362.6 182.3 105.9 361.1 152.0 183.0 175.9 197.6 152.3 834.7 152.0 161.1 154.8 369.8 155.1 216.4 125.5 378.3 162.3 350.5 913.1 134.0 186.6 145.5 377.6 322.5 497.0 182.1 400.9 291.9 297.5 259.9 227.0 207.6 241.4 229.1 389.7 317.3 243.1 331.7 289.9 441.7 155.4 167.0 333.4 194.1 399.5 556.9 179.1 442.3 461.3 230.0 279.2 231.0 331.6 287.5 227.0 138.2 201.3 368.1 338.8 311.2 289.9 343.2 945.8 448.2 719.4 424.0 670.0 585.0 251.1 174.6 569.4 492.0 634.2 369.0 359.3 310.4 513.8 281.0 205.7 222.9 315.7 295.2 307.0 179.2 365.6 401.5 267.6 567.2 457.2 469.0 447.7 395.8 713.9 1045.5 503.4 779.4 1117.0 673.3 1009.8 755.0 768.2 1161.9 787.8 800.5 793.7 85.6 823.9 1037.9 926.9 772.0 1795.1 347.4 363.9 377.3 441.6 343.6 369.1 359.0 355.8 361.1 369.8 378.3 377.6 262.7 189.1 238.4 25.5 191.1 226.5 289.3 693.4 128.1 181.9 458.3 514.8 3191.4 351.8 398.1 673.1 98.0 555.4 275.3 776.2 1997.6 373.9 901.2 294.2 298.4 283.6 428.7 143.7 19.9 314.4 466.6 327.2 307.3 366.3 280.6 212.8 205.6 1079.3 710.8 139.7 22.7 576.3 687.7 280.3 337.3 246.9 222.7 336.5 434.0 13.1 356.7 367.2 465.5 19.6 42.3 279.4 647.9 243.8 210.7 440.1 867.3 2437.9 370.2 284.1 197.2 199.2 372.0 77.0 208.6 321.9 280.6 515.0 241.7 288.6 669.6 435.8 NDUFB4 B15 ENSG00000065518 "NADH:ubiquinone oxidoreductase subunit B4" O95168 3 120596328-120602507 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 945.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1493.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051739, HPA064441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Nuclear membrane" "HPA051739: AB_2681585, HPA064441: " "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.95e-2)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.35e-3)" "unprognostic (9.66e-3)" "unprognostic (7.97e-2)" "unprognostic (2.84e-1)" "unprognostic (3.69e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "prognostic favorable (1.79e-4)" 148.6 338.4 159.7 90.3 169.1 112.4 145.1 175.9 203.2 126.2 173.2 170.0 147.8 117.9 133.8 159.5 113.0 85.7 619.5 163.5 178.4 232.4 187.4 102.9 93.8 168.3 163.0 119.8 137.4 260.3 170.2 76.8 168.6 118.1 148.7 100.2 148.4 117.4 945.3 144.5 135.6 103.4 170.7 112.1 162.3 106.5 161.7 125.6 113.1 562.2 114.2 133.5 142.1 172.8 294.8 204.3 246.7 248.5 151.0 181.4 199.2 157.0 212.1 205.4 224.5 200.9 219.8 147.8 311.6 177.8 255.6 272.5 191.3 202.7 155.7 227.5 212.6 226.1 205.7 208.1 90.4 202.7 256.8 161.3 268.5 98.9 125.8 246.0 258.5 271.7 138.5 219.2 220.9 224.1 398.6 294.8 193.9 478.9 554.7 228.8 141.0 325.8 337.3 177.9 273.8 283.4 186.5 205.7 360.0 162.0 348.0 319.9 199.8 179.0 233.2 76.9 226.5 263.2 260.1 454.3 283.6 279.8 250.8 205.0 164.8 197.2 156.0 229.5 162.2 231.6 215.2 176.8 213.9 176.3 182.2 181.8 101.6 152.7 238.2 267.9 300.6 205.7 159.7 169.1 175.9 203.2 163.5 178.4 168.3 163.0 168.6 170.7 161.7 172.8 274.1 163.5 162.6 36.9 167.0 222.3 289.0 612.6 190.6 137.8 290.1 351.3 1493.1 311.7 348.3 320.0 58.4 366.0 158.1 472.4 1226.7 556.7 999.2 259.9 188.9 235.7 298.7 196.9 22.6 620.9 421.0 213.7 175.3 293.5 174.8 139.4 183.5 513.9 330.3 84.1 22.0 526.3 451.6 240.2 247.9 164.6 275.2 196.2 434.0 15.9 339.2 340.7 186.4 13.0 31.2 567.9 581.8 277.2 283.2 243.2 613.4 1225.1 266.2 168.4 256.4 208.1 259.0 418.9 87.5 288.4 251.5 352.4 168.1 271.3 462.8 344.0 NDUFB5 "CI-SGDH, MGC12314, SGDH" ENSG00000136521 "NADH:ubiquinone oxidoreductase subunit B5" O43674 3 179604690-179627647 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 241.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005640 Enhanced Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA005640: AB_1079461" "unprognostic (6.76e-2)" "unprognostic (1.09e-2)" "unprognostic (6.33e-2)" "unprognostic (3.51e-3)" "unprognostic (1.38e-1)" "unprognostic (7.35e-3)" "unprognostic (1.33e-2)" "unprognostic (1.63e-1)" "unprognostic (4.46e-2)" "unprognostic (5.96e-3)" "unprognostic (4.83e-2)" "unprognostic (7.11e-2)" "prognostic favorable (3.32e-5)" "unprognostic (3.05e-1)" "unprognostic (1.36e-1)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" 61.0 88.4 35.6 29.0 38.5 19.5 47.8 39.4 57.3 37.7 52.8 64.0 75.1 30.2 15.6 56.7 33.4 28.8 217.0 38.4 40.0 93.5 74.0 34.4 36.1 37.1 36.6 41.9 52.3 66.6 40.2 27.0 37.4 32.6 36.1 22.7 43.7 20.2 241.4 43.6 57.0 22.3 35.4 46.3 63.8 42.2 39.8 31.4 41.6 166.9 24.8 46.2 41.5 38.9 96.5 23.2 51.2 66.8 52.3 66.0 75.6 58.5 42.0 48.1 50.7 79.8 53.4 72.7 193.4 32.7 119.5 89.9 48.9 47.4 38.9 182.5 43.1 90.4 31.2 44.8 52.3 97.9 64.0 64.9 60.7 31.2 51.0 61.0 62.8 62.1 71.2 98.7 51.8 68.8 55.8 60.5 80.2 138.7 80.8 64.2 63.3 205.1 82.5 46.8 41.1 62.4 34.9 169.9 126.7 36.2 265.9 151.2 64.5 46.6 47.8 61.7 139.9 158.0 193.6 122.5 75.8 91.7 67.9 94.6 104.5 49.9 43.8 127.8 64.5 90.2 60.0 51.6 145.5 67.2 59.8 62.9 18.9 48.1 154.8 81.0 84.0 105.6 35.6 38.5 39.4 57.3 38.4 40.0 37.1 36.6 37.4 35.4 39.8 38.9 113.6 48.1 48.5 17.3 90.2 85.1 115.2 374.4 73.4 45.9 121.0 138.6 362.3 88.6 164.3 88.3 33.3 234.0 54.5 115.9 508.7 132.5 162.6 118.4 79.0 89.2 117.5 75.3 16.1 105.7 150.0 87.1 77.5 62.9 93.8 120.1 105.7 118.3 253.5 40.4 22.6 196.0 266.5 261.3 133.0 28.9 81.1 133.6 135.2 15.9 180.0 107.2 70.0 19.6 25.8 81.5 163.4 70.0 75.0 89.8 293.5 462.8 157.9 73.4 72.3 87.1 98.5 265.7 128.3 105.9 88.7 230.0 72.9 257.4 268.8 163.4 NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 583.9;Distal tubular cells: 534.1;Early spermatids: 889.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044001, HPA053334" Supported Enhanced Mitochondria No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA044001: AB_10959448, HPA053334: AB_2682116" "unprognostic (4.09e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.81e-2)" "unprognostic (1.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-3)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.47e-10)" "unprognostic (2.70e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" 38.6 50.8 42.7 30.7 45.3 31.0 35.9 47.1 48.1 34.1 42.8 41.8 44.6 38.1 26.8 43.8 36.0 17.6 144.9 44.5 46.5 73.6 66.7 30.5 26.9 44.5 42.9 29.7 31.0 41.8 40.3 22.5 44.6 28.5 29.1 30.7 37.0 22.0 168.0 28.2 43.6 26.7 45.9 28.8 43.5 53.5 44.3 28.7 33.2 101.8 24.5 34.1 33.4 47.1 106.4 63.7 69.6 80.1 46.7 43.0 44.5 69.5 56.5 62.8 68.8 62.8 46.5 78.4 70.5 48.2 65.1 58.8 66.5 76.8 47.0 108.6 106.0 187.2 88.8 65.9 45.2 94.4 46.3 44.8 36.7 56.8 42.9 47.5 57.6 118.4 61.0 86.1 71.9 61.2 128.1 221.2 73.6 90.7 140.1 86.7 58.4 73.1 72.0 39.3 69.7 78.4 80.2 91.1 50.7 52.0 86.3 72.0 51.4 67.9 103.8 75.7 103.8 38.0 77.0 131.5 113.7 65.6 32.7 126.3 97.6 136.1 76.9 94.3 74.5 106.0 81.4 80.0 108.8 89.0 82.3 87.4 302.1 91.9 116.3 152.7 112.4 110.2 42.7 45.3 47.1 48.1 44.5 46.5 44.5 42.9 44.6 45.9 44.3 47.1 69.5 125.0 111.6 15.3 76.2 94.2 106.2 222.9 90.0 44.1 64.6 72.6 583.9 101.5 141.4 108.5 6.2 191.8 69.4 115.8 534.1 172.5 889.5 106.9 86.1 101.0 64.6 196.7 21.8 166.7 143.0 109.5 83.6 86.4 90.5 64.3 74.3 182.2 160.8 18.5 23.8 152.5 209.5 55.0 96.4 146.9 91.6 78.4 160.1 3.7 108.6 115.3 90.6 18.1 21.3 144.4 124.9 89.9 165.7 80.0 201.0 520.3 152.3 56.5 105.2 94.8 151.3 182.0 125.9 139.7 96.7 104.1 81.0 95.6 167.3 103.8 NDUFB7 "B18, CI-B18, MGC2480" ENSG00000099795 "NADH:ubiquinone oxidoreductase subunit B7" P17568 19 14566078-14572066 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002817 Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002817: AB_1079462" "unprognostic (2.80e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.03e-1)" "unprognostic (4.09e-2)" "unprognostic (4.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.95e-1)" "unprognostic (1.45e-3)" "unprognostic (2.07e-1)" "unprognostic (1.87e-2)" "unprognostic (2.02e-2)" "unprognostic (4.14e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.40e-1)" "unprognostic (1.69e-1)" "unprognostic (1.59e-1)" "unprognostic (9.25e-3)" 203.1 216.1 209.9 66.1 218.4 103.7 188.8 232.4 325.4 153.6 216.5 256.3 124.6 169.4 51.1 230.7 152.3 57.7 695.8 204.8 222.5 291.7 335.7 127.8 70.4 222.2 221.3 137.3 213.5 143.2 182.8 61.6 218.9 171.0 55.9 28.6 198.7 93.2 709.4 189.4 163.2 50.6 213.2 150.0 231.9 132.8 230.2 50.6 189.7 266.9 39.5 167.3 161.2 222.6 242.1 237.4 95.0 203.1 80.4 80.5 167.4 110.1 120.6 200.0 189.2 317.9 130.2 109.4 322.0 102.9 87.5 185.0 62.6 241.1 26.7 170.1 320.8 212.2 380.9 334.6 142.1 138.7 141.5 131.7 196.6 105.7 49.6 56.1 161.7 194.9 132.9 194.8 94.2 452.7 227.0 308.0 242.4 228.1 773.2 174.3 112.8 264.6 143.0 253.3 204.4 217.6 114.9 265.6 303.4 24.6 175.0 245.1 122.0 253.5 123.2 324.4 207.0 264.4 295.5 144.1 243.7 267.8 174.5 355.6 414.5 140.4 432.9 395.5 403.8 368.6 291.4 368.9 415.4 327.7 241.3 315.5 119.4 422.4 389.5 460.4 373.3 562.3 209.9 218.4 232.4 325.4 204.8 222.5 222.2 221.3 218.9 213.2 230.2 222.6 196.4 76.9 95.9 19.9 155.6 133.4 177.9 358.5 126.9 117.4 285.4 363.9 670.4 245.9 214.2 259.3 56.3 359.7 155.5 937.3 1154.3 324.9 81.8 162.8 133.9 163.5 332.1 152.9 7.4 455.3 330.5 185.2 194.7 152.1 102.2 197.4 203.1 589.1 377.5 72.3 11.4 639.3 299.1 237.9 158.0 252.0 207.5 173.9 378.8 10.3 327.3 236.4 365.6 8.5 25.5 367.9 720.8 200.1 197.5 175.4 916.4 1041.9 193.1 152.4 236.7 193.6 330.8 133.7 252.1 235.7 161.2 225.6 138.6 197.5 631.6 220.1 NDUFB8 "ASHI, CI-ASHI" ENSG00000166136 "NADH:ubiquinone oxidoreductase subunit B8" O95169 10 100523740-100530000 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 876.5;Proximal tubular cells: 881.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA003886, HPA065549" Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA003886: AB_1079463, HPA065549: " "unprognostic (4.07e-2)" "unprognostic (1.95e-3)" "unprognostic (2.28e-1)" "unprognostic (7.33e-2)" "unprognostic (4.88e-2)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (6.46e-2)" "unprognostic (8.33e-2)" "unprognostic (9.09e-2)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-2)" 152.6 199.3 431.2 103.4 439.3 171.5 135.8 427.1 606.3 127.3 416.7 237.8 161.0 145.8 163.0 170.2 132.4 88.0 482.4 444.8 441.9 249.9 262.0 108.6 132.0 438.5 439.4 130.4 115.5 331.0 186.7 83.0 441.9 132.2 145.0 127.1 163.6 135.8 408.9 128.2 147.8 125.5 411.8 133.3 201.0 66.2 442.5 140.6 130.1 512.8 119.9 162.9 132.9 448.3 250.2 419.6 222.3 383.1 159.6 158.8 238.5 168.1 370.9 259.3 278.8 575.4 278.1 260.7 146.4 185.6 189.1 289.5 162.9 269.7 194.5 172.9 417.8 183.9 350.3 465.7 217.6 379.3 302.6 191.6 240.7 249.2 329.3 180.4 283.7 361.1 194.5 159.3 218.4 304.1 369.7 472.9 144.7 324.3 377.9 252.4 237.6 346.1 298.8 281.3 147.9 209.7 122.0 227.4 250.9 147.3 338.2 332.8 185.5 139.5 158.7 151.5 296.8 288.4 286.4 334.8 277.6 398.2 159.3 299.4 530.8 478.1 406.0 558.8 483.1 616.1 498.0 468.1 589.7 546.7 538.1 514.0 122.7 478.0 489.6 655.0 817.6 1113.4 431.2 439.3 427.1 606.3 444.8 441.9 438.5 439.4 441.9 411.8 442.5 448.3 184.8 76.9 132.7 41.8 107.6 0.0 187.1 0.0 12.5 186.4 162.2 210.2 392.9 204.5 48.3 198.6 58.4 333.1 175.8 109.0 876.5 268.1 24.9 105.8 86.3 142.7 105.6 114.3 72.6 264.7 305.1 128.8 35.2 87.1 109.7 112.0 153.8 346.5 399.1 153.1 82.6 171.6 0.0 184.4 0.0 56.0 218.1 142.2 0.0 33.7 231.0 219.5 158.6 40.2 62.3 250.6 191.7 217.4 59.3 203.2 560.2 881.6 85.2 183.5 170.9 117.2 176.0 85.5 83.1 31.5 0.0 307.7 112.9 225.5 237.6 221.5 NDUFC1 KFYI ENSG00000109390 "NADH:ubiquinone oxidoreductase subunit C1" O43677 4 139266880-139302551 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 83.5;skeletal muscle: 268.3;tongue: 158.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1840.3;Distal tubular cells: 1136.7;Proximal tubular cells: 1449.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044556, HPA062427" Enhanced Approved Mitochondria No No "Cluster 24: B-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044556: AB_10794402, HPA062427: " "unprognostic (6.07e-2)" "unprognostic (4.61e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.23e-5)" "unprognostic (7.11e-2)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.96e-4)" "unprognostic (2.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "prognostic favorable (7.25e-4)" 9.5 15.3 19.9 8.0 20.4 9.1 11.0 22.4 28.6 7.4 21.3 18.6 23.8 8.1 14.3 10.5 10.5 5.4 83.5 19.6 20.8 26.7 24.1 8.8 10.1 20.3 21.0 10.0 14.8 22.9 15.8 5.9 21.6 9.7 19.0 23.5 18.9 14.4 268.3 13.2 18.6 7.4 19.5 10.4 17.0 12.7 20.5 8.6 14.8 158.5 11.0 8.6 7.9 22.4 21.4 5.9 19.2 30.8 17.7 22.7 20.5 20.1 13.1 11.1 10.4 13.1 23.7 7.7 7.7 15.5 14.9 10.5 38.6 18.2 15.0 13.0 13.5 11.9 13.5 23.0 18.1 11.2 10.1 24.5 18.2 14.4 21.6 16.8 17.5 17.8 25.3 33.8 11.0 17.8 17.8 32.1 16.3 44.1 11.7 14.9 10.6 52.6 24.6 14.2 14.6 14.7 13.8 23.2 10.5 15.6 23.7 23.2 8.1 24.2 6.4 13.0 13.5 23.2 49.5 18.5 18.9 26.7 13.8 26.2 10.1 13.1 8.5 10.3 11.6 7.1 11.7 11.5 8.9 15.9 10.5 11.4 3.0 10.1 14.2 16.2 18.2 10.8 19.9 20.4 22.4 28.6 19.6 20.8 20.3 21.0 21.6 19.5 20.5 22.4 201.8 89.8 145.7 15.7 95.8 140.2 173.3 402.7 185.0 120.4 240.3 349.6 1840.3 221.6 240.1 439.6 33.3 147.4 71.7 343.0 1136.7 270.3 409.9 333.5 115.5 162.7 221.4 175.2 10.9 336.9 166.2 176.9 158.0 196.8 73.3 151.2 133.5 432.9 225.1 119.5 14.3 340.5 276.7 102.0 65.7 70.9 169.3 115.6 266.8 6.5 185.5 446.6 79.3 8.0 13.3 265.3 355.8 206.5 155.6 173.7 471.7 1449.6 297.1 139.1 98.6 159.3 184.4 439.0 197.4 290.1 179.3 118.1 83.5 224.7 343.7 176.0 NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159509 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 181.7;skeletal muscle: 221.6;tongue: 225.2" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Enhanced Supported Mitochondria NA NA 48000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB070844: , HPA064605: AB_2685297" "prognostic unfavorable (3.85e-4)" "unprognostic (1.76e-1)" "unprognostic (9.22e-3)" "unprognostic (5.01e-2)" "unprognostic (8.63e-3)" "unprognostic (3.75e-1)" "unprognostic (3.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.47e-12)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" "unprognostic (4.73e-2)" 27.1 61.6 8.3 13.3 10.8 13.2 23.8 14.9 16.1 19.5 39.7 35.3 29.9 19.3 10.8 36.2 16.3 10.5 181.7 10.7 13.7 48.0 51.8 18.3 12.6 10.1 10.1 14.6 19.2 47.2 20.2 14.4 11.7 15.8 30.0 24.4 27.7 15.6 221.6 26.6 26.1 16.4 9.2 16.8 37.1 20.8 14.2 15.6 17.9 225.2 16.9 22.4 22.4 12.5 28.3 27.6 39.2 28.6 35.8 28.9 45.4 40.4 43.4 66.0 47.6 72.0 32.1 31.7 34.8 50.8 65.5 38.5 52.9 39.2 58.2 14.6 24.9 63.5 65.1 64.9 37.0 46.2 27.5 35.3 22.5 51.9 40.4 29.6 52.3 39.3 69.8 31.1 43.6 35.2 38.5 30.7 36.5 47.2 48.6 38.3 54.7 55.1 54.7 50.7 38.1 29.8 46.7 45.1 67.1 53.3 39.8 44.2 40.1 36.2 32.0 35.8 39.1 29.8 38.4 46.9 36.3 37.5 37.8 14.1 12.9 15.7 12.4 15.2 9.6 9.6 10.8 11.8 14.7 9.0 9.6 11.1 9.2 12.5 22.5 7.8 15.9 9.5 8.3 10.8 14.9 16.1 10.7 13.7 10.1 10.1 11.7 9.2 14.2 12.5 32.4 60.9 33.0 45.1 23.8 16.2 21.7 40.8 30.1 97.1 19.3 14.0 582.5 48.6 42.8 38.6 120.9 48.4 18.8 74.5 93.9 44.2 14.5 49.8 49.8 36.6 51.0 42.0 67.8 28.2 33.7 42.3 48.4 54.5 37.3 42.3 29.3 94.5 34.0 117.8 72.8 47.9 54.9 31.2 10.7 7.0 33.5 27.7 30.2 28.1 37.2 62.7 27.8 45.2 41.6 32.1 46.4 44.8 31.0 19.9 77.8 102.3 53.5 81.5 32.9 55.2 60.8 58.2 49.5 40.8 16.6 52.5 23.7 71.5 69.9 26.6 NDUFS4 "AQDQ, CI-18" ENSG00000164258 "NADH:ubiquinone oxidoreductase subunit S4" O43181 5 53560633-53683338 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 397.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 553.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003884 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003884: AB_1079465" "unprognostic (1.25e-1)" "unprognostic (3.61e-3)" "unprognostic (3.44e-2)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" "unprognostic (6.73e-3)" "unprognostic (6.93e-2)" "unprognostic (1.11e-1)" "unprognostic (3.93e-1)" "unprognostic (4.38e-1)" "unprognostic (1.72e-2)" "unprognostic (3.11e-1)" "prognostic favorable (3.85e-6)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" 94.2 80.6 71.3 37.0 71.8 50.9 99.9 75.1 101.8 82.0 70.6 93.2 83.6 65.0 68.6 80.6 69.5 50.2 190.5 70.3 78.3 137.2 147.9 55.7 45.7 72.3 70.4 101.7 45.4 125.8 58.2 63.0 73.8 65.9 89.6 59.1 63.6 73.6 346.2 76.7 71.9 72.2 75.3 42.9 80.7 37.9 75.1 59.8 74.0 397.4 60.7 71.3 73.0 77.7 118.8 102.9 200.5 119.1 133.9 192.7 167.9 140.7 136.6 153.0 185.8 126.7 151.4 83.9 180.2 121.1 146.3 85.3 72.0 167.9 175.4 77.4 137.2 57.8 97.1 115.6 142.4 141.0 95.8 161.2 190.2 105.8 184.8 167.7 135.1 93.4 50.2 88.5 141.9 110.5 106.7 116.9 60.9 45.3 115.1 126.4 113.1 166.2 165.1 113.0 92.7 99.5 96.4 92.5 175.2 106.8 148.2 145.2 104.4 93.6 98.9 68.7 186.9 67.6 91.5 102.1 99.7 202.7 137.3 19.4 83.9 7.9 49.1 101.8 55.3 72.7 61.9 58.0 121.6 50.3 68.2 70.0 6.8 79.4 108.3 93.8 72.4 68.2 71.3 71.8 75.1 101.8 70.3 78.3 72.3 70.4 73.8 75.3 75.1 77.7 62.1 38.5 56.6 49.0 52.6 125.8 150.4 382.0 56.3 44.8 100.0 119.1 328.4 82.9 170.6 84.6 41.7 168.4 43.2 124.5 553.7 174.1 61.5 65.5 87.7 84.6 90.4 47.1 55.9 167.3 163.3 113.1 47.9 68.7 76.0 146.9 99.2 137.8 144.3 30.3 73.2 135.3 215.7 76.4 127.3 61.5 157.5 70.4 117.4 38.4 161.4 113.6 63.8 52.8 68.4 179.4 153.4 152.7 38.4 95.3 188.7 425.9 112.2 76.0 124.9 145.1 173.4 76.8 75.0 79.3 101.4 179.9 50.0 96.4 171.2 158.2 NDUFS5 CI-15k ENSG00000168653 "NADH:ubiquinone oxidoreductase subunit S5" O43920 1 39026318-39034636 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2057.9;Proximal tubular cells: 1739.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042582 Supported NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA042582: AB_2678062" "unprognostic (1.49e-2)" "unprognostic (2.62e-2)" "unprognostic (3.58e-1)" "unprognostic (1.41e-2)" "unprognostic (5.00e-2)" "unprognostic (2.93e-2)" "unprognostic (2.97e-3)" "unprognostic (8.96e-2)" "unprognostic (7.31e-2)" "prognostic favorable (3.54e-4)" "unprognostic (1.29e-1)" "unprognostic (7.07e-2)" "unprognostic (2.40e-1)" "unprognostic (7.87e-3)" "unprognostic (2.88e-1)" "unprognostic (2.52e-3)" "unprognostic (8.08e-2)" 343.8 373.0 538.9 184.4 542.6 266.0 296.9 532.6 830.4 253.2 515.0 461.2 220.1 315.4 565.3 363.3 265.7 167.1 1277.8 542.3 540.7 399.5 379.3 236.9 176.8 552.2 538.3 304.8 234.1 354.2 333.3 170.2 541.7 292.4 342.3 206.7 274.1 299.5 954.0 284.9 240.5 259.4 524.1 185.2 339.9 121.3 543.4 240.1 250.6 1115.6 245.5 322.3 273.9 568.5 447.7 781.3 548.2 698.8 593.9 622.8 749.7 501.6 406.3 488.6 490.3 868.9 596.3 469.0 700.2 541.6 248.9 308.9 732.5 688.3 543.1 546.2 856.8 491.8 1291.1 1622.7 407.4 1015.6 366.8 650.5 816.8 537.4 476.0 497.3 858.3 500.8 817.0 430.9 250.4 1030.4 468.4 1291.3 1000.5 654.5 785.8 648.7 815.5 806.7 1027.9 1482.9 741.7 710.6 583.9 773.6 712.8 1174.2 520.2 753.1 545.7 390.9 463.1 409.8 874.3 353.5 770.5 732.6 449.7 1110.5 567.4 186.2 264.6 159.6 227.6 293.9 262.8 196.4 353.2 268.4 275.3 158.3 359.9 316.3 51.7 205.9 282.5 340.5 361.7 341.2 538.9 542.6 532.6 830.4 542.3 540.7 552.2 538.3 541.7 524.1 543.4 568.5 260.1 166.7 196.0 16.6 197.1 460.9 390.6 958.6 187.2 128.6 337.9 400.8 2057.9 391.7 407.6 551.8 37.5 638.9 248.2 570.5 1367.6 581.1 134.7 487.4 454.0 288.4 407.8 230.8 17.0 543.4 647.0 377.8 246.2 508.5 209.8 544.6 271.6 638.8 545.9 99.3 18.7 652.0 539.1 298.1 385.5 121.4 351.9 297.5 457.2 10.3 361.8 307.3 207.0 13.6 24.0 609.1 517.7 422.8 247.6 484.1 576.2 1739.7 343.3 180.6 282.7 417.4 450.5 121.8 99.2 418.8 460.3 525.2 292.2 275.9 697.1 454.2 NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 606.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Supported Approved Nucleoplasm,Mitochondria,Cytosol No No 7600 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Nucleoplasm, Cytosol" "HPA003404: AB_1079466, HPA077896: AB_2686866" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.89e-1)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "unprognostic (6.72e-3)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.56e-2)" "unprognostic (1.95e-3)" 97.4 171.6 94.3 69.2 97.4 149.8 101.7 106.8 139.7 63.9 106.0 124.2 102.3 69.7 91.1 142.6 64.0 68.7 419.3 96.7 106.0 180.7 404.2 88.6 105.0 105.9 104.4 52.4 111.6 136.7 72.1 73.7 105.9 88.5 119.8 129.9 97.4 72.4 606.9 94.7 100.5 80.6 103.7 86.4 133.8 79.6 102.7 90.2 72.7 538.3 105.1 122.1 76.5 104.6 136.5 139.8 159.1 148.4 116.6 164.0 133.4 165.4 266.5 217.7 205.5 265.1 109.4 209.4 149.5 158.6 200.3 66.9 157.5 175.5 208.8 104.6 136.6 133.0 135.3 364.8 133.6 373.8 159.2 139.2 144.3 134.9 146.2 156.8 239.3 184.3 216.5 644.0 204.6 171.6 263.5 328.9 131.4 750.5 172.3 124.5 118.2 794.2 354.3 218.7 167.0 122.3 164.6 188.0 220.3 113.6 174.2 282.8 145.8 273.4 194.3 198.8 223.0 180.4 292.3 237.1 195.4 166.0 181.0 250.8 161.8 194.2 118.1 196.1 148.3 237.6 176.9 140.5 237.9 201.1 153.5 142.7 76.0 124.2 187.9 315.1 231.9 231.8 94.3 97.4 106.8 139.7 96.7 106.0 105.9 104.4 105.9 103.7 102.7 104.6 107.3 80.1 145.8 17.6 143.1 148.0 319.0 629.4 159.4 101.2 165.0 167.3 69.9 178.7 339.5 150.8 87.6 344.1 146.6 211.0 876.5 415.2 271.5 160.3 108.2 117.3 106.5 165.4 32.9 531.4 323.3 122.0 144.3 183.9 120.3 109.7 96.4 351.5 313.5 94.2 37.3 201.7 480.1 115.7 267.1 186.2 122.1 170.2 231.3 17.8 293.2 167.1 96.8 32.2 46.5 530.3 201.2 102.0 244.9 554.3 349.9 810.6 293.4 184.2 105.2 124.0 196.3 217.4 175.0 226.5 147.6 289.4 165.7 266.7 227.3 469.0 NDUFV3 CI-10k ENSG00000160194 "NADH:ubiquinone oxidoreductase subunit V3" P56181 21 42879644-42913304 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 770.8;Early spermatids: 502.9;Late spermatids: 1712.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019791, HPA020463, HPA030427, CAB034142" Enhanced Enhanced Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "CAB034142: AB_2298212, HPA019791: AB_1854357, HPA020463: AB_1854358, HPA030427: AB_10603024" "unprognostic (1.62e-1)" "unprognostic (2.17e-3)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.11e-2)" "unprognostic (4.69e-1)" "unprognostic (2.97e-2)" "unprognostic (1.05e-1)" "unprognostic (3.13e-1)" "unprognostic (3.85e-3)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (6.56e-2)" "unprognostic (9.30e-3)" "unprognostic (2.14e-1)" "unprognostic (1.94e-1)" 20.5 18.1 9.2 3.2 9.3 6.8 17.5 9.5 8.9 16.6 7.5 24.2 5.1 19.1 7.9 18.9 17.3 2.4 47.2 7.6 8.0 18.0 26.9 13.7 3.1 9.5 9.7 19.1 24.0 7.5 16.6 3.0 9.2 16.3 4.1 7.7 17.3 4.0 88.0 19.0 16.1 3.6 8.4 17.0 19.7 20.9 9.2 2.5 14.9 21.1 3.2 18.4 15.9 10.1 3.3 4.9 9.1 8.1 7.9 5.0 10.4 6.6 4.2 5.2 3.4 10.6 6.2 4.9 4.2 4.1 11.7 5.4 8.8 8.1 3.5 2.8 7.4 20.1 8.7 9.0 9.4 6.0 7.8 8.0 8.2 6.9 12.0 4.2 6.1 5.6 13.5 7.3 5.6 10.5 3.7 6.2 10.2 15.7 6.9 4.6 5.3 12.3 9.5 7.5 5.8 4.7 9.0 10.3 4.8 4.4 10.2 4.6 8.9 3.2 3.0 4.4 4.8 12.1 7.1 3.5 5.7 7.7 4.6 3.1 5.7 3.8 2.8 7.1 2.4 2.9 2.4 2.2 5.0 3.5 2.9 2.8 3.3 4.4 6.6 4.4 2.7 2.8 9.2 9.3 9.5 8.9 7.6 8.0 9.5 9.7 9.2 8.4 9.2 10.1 42.8 54.5 46.7 14.4 36.5 19.9 53.7 97.7 24.5 81.2 64.9 65.7 770.8 92.9 58.6 90.1 68.8 57.5 32.5 89.3 230.9 86.5 502.9 84.5 64.9 48.1 78.3 112.4 19.4 101.5 59.5 57.2 55.5 56.9 31.6 45.5 68.2 334.5 114.4 57.2 22.1 114.8 87.5 88.3 38.1 1712.0 66.5 62.3 37.4 17.8 86.4 88.7 49.4 15.6 19.5 98.6 80.9 62.4 39.0 109.3 176.4 372.6 85.9 104.7 72.3 54.0 66.1 243.5 77.1 50.0 23.4 89.9 29.9 83.8 95.4 65.3 NEBL "bA165O3.1, C10orf113, LASP2, LNEBL" ENSG00000078114 Nebulette O76041 10 20779973-21293011 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "heart muscle: 312.0" "Cell type enhanced" "Detected in many" "Astrocytes: 951.0;Cardiomyocytes: 2413.0;Excitatory neurons: 359.0;Inhibitory neurons: 436.6;Oligodendrocyte precursor cells: 352.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.4;SCLC-21H: 31.0;SH-SY5Y: 7.2;SK-BR-3: 8.0;TIME: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013994, HPA013995" Approved NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA013994: AB_1854359, HPA013995: AB_1854360" "unprognostic (3.79e-2)" "unprognostic (1.92e-3)" "unprognostic (3.44e-2)" "unprognostic (3.57e-3)" "unprognostic (1.50e-1)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.25e-2)" "unprognostic (1.05e-1)" "unprognostic (6.20e-3)" "unprognostic (2.36e-2)" "unprognostic (8.42e-2)" "prognostic favorable (2.77e-8)" "unprognostic (3.51e-1)" "unprognostic (8.11e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (5.56e-4)" 2.4 2.6 26.3 0.2 25.8 0.0 6.1 29.9 19.1 5.9 0.1 1.3 0.0 0.6 0.1 16.1 0.6 0.4 312.0 26.6 29.6 13.1 1.2 16.2 0.2 31.0 35.2 1.1 7.0 1.2 22.1 3.7 27.5 8.7 1.0 2.6 18.0 2.9 0.6 14.9 1.3 0.4 28.6 0.2 3.2 2.7 35.2 0.6 21.5 0.4 1.2 2.1 12.8 24.9 0.4 3.5 3.8 0.1 0.0 0.0 7.4 0.0 0.0 0.1 0.0 0.9 0.5 0.5 5.5 0.0 0.1 2.5 0.2 0.0 0.0 0.0 3.5 0.0 1.8 0.0 2.9 0.0 0.0 3.3 3.6 0.0 0.6 0.0 0.0 0.2 0.3 0.5 0.0 3.5 0.1 0.0 1.0 0.7 1.9 0.0 0.0 0.1 0.3 0.6 31.0 7.2 1.5 8.0 0.0 0.2 4.7 0.0 6.6 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.3 25.8 29.9 19.1 26.6 29.6 31.0 35.2 27.5 28.6 35.2 24.9 17.2 218.0 67.2 951.0 0.0 18.4 12.6 6.1 0.0 91.4 51.6 24.8 2413.0 15.7 19.9 33.1 39.6 15.3 1.0 7.5 29.4 2.9 331.4 17.4 3.9 20.8 18.0 0.0 359.0 7.1 11.1 61.0 8.6 47.3 0.0 1.0 0.7 0.2 2.1 146.4 436.6 19.5 14.2 0.6 2.3 61.7 3.7 1.2 12.4 206.1 5.9 4.0 0.0 352.3 9.0 12.9 25.7 4.9 0.0 17.3 5.5 7.7 39.1 10.3 0.0 0.8 14.8 2.8 1.1 33.8 46.2 36.8 1.8 4.5 13.7 33.9 NECAB3 "APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51" ENSG00000125967 "N-terminal EF-hand calcium binding protein 3" Q96P71 20 33657087-33674463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 93.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044785, HPA070595, HPA071786" Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA044785: AB_2679086, HPA070595: AB_2732158, HPA071786: AB_2732186" "unprognostic (8.95e-2)" "unprognostic (1.45e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.44e-1)" "unprognostic (4.05e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.19e-5)" "unprognostic (3.13e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (6.13e-2)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-1)" 10.2 55.9 20.1 2.2 21.2 1.5 10.4 18.9 33.9 11.8 20.4 14.4 13.6 9.1 6.9 8.9 10.9 4.5 45.7 21.7 21.2 13.3 13.3 11.1 2.3 23.3 19.1 41.2 19.1 17.5 10.3 3.9 24.4 27.2 4.4 6.5 13.6 7.8 60.3 6.9 10.6 3.7 16.6 6.5 30.5 10.6 23.2 1.9 19.2 31.7 1.7 14.6 10.0 22.3 8.2 7.1 5.1 10.5 4.0 7.8 24.6 11.2 4.2 7.1 6.2 33.2 5.3 9.1 26.2 6.6 16.7 9.7 5.3 3.3 2.6 3.2 7.7 8.7 30.7 39.3 10.5 2.1 8.0 9.7 4.8 6.6 2.1 7.6 4.8 4.8 12.6 4.8 9.3 12.5 3.3 8.6 2.2 8.7 17.5 9.7 13.3 15.9 6.6 6.1 32.4 9.0 26.1 28.7 12.0 5.6 36.6 10.4 4.0 8.6 12.4 11.3 12.7 17.7 7.8 17.1 16.9 4.0 3.8 0.0 1.3 1.8 0.3 1.3 0.9 0.2 0.6 0.3 1.2 0.9 0.4 0.1 0.0 1.2 3.5 0.0 1.6 0.6 20.1 21.2 18.9 33.9 21.7 21.2 23.3 19.1 24.4 16.6 23.2 22.3 5.4 16.0 45.5 14.7 4.1 3.1 6.5 2.7 8.6 19.4 20.5 11.6 29.9 10.0 5.9 5.5 8.4 20.6 3.8 22.5 33.2 3.7 93.1 5.7 7.2 2.4 19.9 4.0 13.0 7.5 26.1 12.5 26.5 5.4 3.8 14.0 2.2 9.1 8.9 8.4 14.5 16.2 4.1 6.0 6.2 54.0 26.4 5.5 12.4 1.0 3.6 18.2 2.1 6.0 4.5 4.4 15.1 23.7 11.7 14.2 45.9 12.2 3.8 20.8 6.6 9.2 12.1 20.5 20.6 9.3 3.1 20.7 5.4 23.9 20.0 10.0 NEK10 FLJ32685 ENSG00000163491 "NIMA related kinase 10" Q6ZWH5 3 27110085-27369460 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 36.6;tongue: 20.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 123.5;Endometrial ciliated cells: 59.3;Excitatory neurons: 131.4;Inhibitory neurons: 130.2;Late spermatids: 61.7;Respiratory ciliated cells: 104.2" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 6.0;LHCN-M2: 8.2;U-2 OS: 6.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038941 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Vesicles Nucleoplasm "HPA038941: AB_10673600" "prognostic favorable (4.20e-4)" "unprognostic (2.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.15e-2)" "unprognostic (3.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-2)" "unprognostic (2.20e-3)" "unprognostic (1.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-2)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" 0.2 0.3 3.0 0.3 5.3 0.3 14.0 0.0 9.4 1.4 3.3 2.0 2.5 0.8 8.3 1.8 11.0 1.4 3.3 9.6 5.0 1.7 2.5 2.4 0.5 3.3 5.7 0.7 0.7 0.4 3.4 0.1 2.7 1.7 0.5 6.2 0.3 1.2 12.4 0.3 0.8 0.3 2.3 0.4 1.0 36.6 6.1 0.5 0.7 20.0 0.6 1.2 0.2 0.9 0.8 1.6 0.8 0.9 0.6 1.5 0.3 6.0 0.9 1.6 1.4 0.0 0.4 0.5 1.4 2.5 1.1 0.1 0.4 0.4 1.7 1.1 0.6 0.1 3.4 2.9 0.1 0.3 0.8 1.8 0.4 2.5 0.1 2.0 1.1 3.4 0.1 0.6 8.2 0.1 0.6 0.4 0.5 0.2 0.2 0.8 0.3 0.2 3.0 0.5 0.1 0.2 0.9 0.3 0.4 0.5 4.8 0.3 0.7 4.3 6.8 0.2 0.6 0.2 0.2 0.4 3.6 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 5.3 0.0 9.4 9.6 5.0 3.3 5.7 2.7 2.3 6.1 0.9 1.5 6.4 0.0 11.4 0.3 0.3 0.3 3.2 0.0 14.5 25.8 7.4 12.9 4.3 9.3 1.8 87.6 0.0 0.8 0.2 0.0 0.4 123.5 59.3 1.3 2.4 0.0 0.0 131.4 0.0 0.3 3.1 0.0 7.7 0.0 1.1 0.7 1.3 0.2 0.0 130.2 0.4 12.2 1.0 0.8 61.7 1.8 1.1 0.0 32.8 0.1 1.0 1.0 20.6 12.9 0.2 2.7 1.2 0.1 1.9 2.1 0.3 104.2 19.1 0.0 14.9 2.4 32.2 2.2 0.1 0.4 0.0 1.1 3.7 0.6 0.4 NFE2L1 "FLJ00380, LCR-F1, NRF1, TCF11" ENSG00000082641 "Nuclear factor, erythroid 2 like 1" Q14494 17 48048329-48061545 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1357.5;tongue: 858.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063384, HPA065424" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA063384: AB_2684998, HPA065424: AB_2685488" "unprognostic (3.19e-1)" "unprognostic (2.41e-1)" "unprognostic (5.44e-2)" "prognostic favorable (8.20e-5)" "unprognostic (5.25e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.20e-2)" "unprognostic (5.58e-2)" "unprognostic (9.30e-2)" "unprognostic (2.61e-1)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.79e-6)" "unprognostic (2.20e-1)" "unprognostic (4.09e-2)" "unprognostic (6.19e-3)" "unprognostic (2.01e-2)" 154.3 130.5 109.3 75.0 99.3 31.1 91.1 101.6 98.3 103.5 225.0 107.6 106.0 149.4 88.2 126.0 130.6 97.3 430.8 112.4 146.3 159.6 104.0 83.3 63.8 135.0 131.1 148.8 65.2 115.2 82.5 100.6 131.0 95.7 80.1 67.1 92.1 123.5 1357.5 121.1 113.3 141.0 116.3 113.0 79.0 69.3 126.8 62.3 132.6 858.4 59.2 89.7 86.3 138.2 122.2 265.4 172.0 147.4 349.8 168.2 128.6 193.7 269.2 135.1 149.8 327.6 137.6 139.8 379.2 244.6 175.2 245.5 122.5 154.5 144.7 239.9 104.1 78.8 181.0 111.1 418.6 178.0 122.1 232.6 380.7 246.7 267.2 228.7 214.6 93.5 142.5 377.4 169.4 103.3 115.5 56.0 113.0 110.0 101.4 80.1 241.8 136.4 150.0 181.0 105.8 160.2 132.4 89.0 272.4 222.5 175.7 120.5 291.2 324.2 141.4 112.3 197.4 626.6 460.1 134.1 310.4 73.6 191.3 14.2 11.8 4.0 3.4 6.5 2.0 5.2 3.1 3.5 2.6 4.9 2.4 2.7 26.1 3.0 8.7 12.9 1.2 1.3 109.3 99.3 101.6 98.3 112.4 146.3 135.0 131.1 131.0 116.3 126.8 138.2 60.1 57.7 49.4 25.1 15.8 55.7 19.3 45.0 34.1 68.8 39.2 33.8 303.1 50.1 34.4 77.3 35.5 22.7 14.7 150.7 25.4 41.3 8.1 57.9 92.0 66.3 30.1 11.6 24.5 36.2 21.5 47.9 27.5 58.8 28.4 89.3 80.3 126.7 36.0 72.3 28.0 51.5 38.7 32.8 18.9 10.6 102.2 23.8 21.4 20.6 31.5 25.4 15.5 9.0 14.4 51.8 64.8 83.8 17.4 33.8 100.3 39.1 49.5 34.8 59.2 39.3 53.8 30.0 35.5 25.9 48.4 22.3 14.2 44.6 49.4 24.4 NFS1 "IscS, NifS" ENSG00000244005 "NFS1 cysteine desulfurase" Q9Y697 20 35668052-35699355 "Enzymes, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034314, HPA051801, HPA054755" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "CAB034314: AB_2235980, HPA051801: AB_2681616, HPA054755: AB_2682594" "unprognostic (1.72e-1)" "unprognostic (2.96e-1)" "unprognostic (1.27e-2)" "unprognostic (5.88e-3)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.14e-1)" "unprognostic (2.02e-1)" "unprognostic (9.00e-2)" "unprognostic (1.73e-1)" "unprognostic (6.52e-3)" "unprognostic (3.93e-2)" "prognostic favorable (4.72e-6)" "unprognostic (2.33e-2)" "unprognostic (1.97e-1)" "unprognostic (1.64e-2)" "unprognostic (5.54e-2)" 12.0 28.7 17.8 7.7 19.0 4.5 10.6 19.5 20.4 11.6 19.0 13.1 12.4 9.1 10.3 11.0 12.5 8.5 22.6 18.2 20.0 42.2 37.7 6.8 8.6 17.4 17.7 13.1 11.9 25.9 12.3 8.6 19.8 9.9 14.1 17.1 13.5 12.6 25.3 10.6 11.1 11.0 17.3 7.7 12.1 19.0 19.6 9.3 10.7 36.5 12.1 9.7 9.1 19.4 29.6 36.0 12.3 13.0 32.7 29.9 24.9 21.9 23.1 32.2 20.9 65.4 16.3 25.1 42.1 20.6 33.3 36.3 42.6 44.5 29.3 11.3 20.0 53.7 37.6 51.4 27.1 22.9 9.9 24.2 41.6 25.5 27.9 24.1 24.6 29.0 38.9 16.3 23.1 45.3 25.8 24.0 14.3 67.1 53.3 10.1 39.9 42.2 33.0 19.6 15.4 14.1 54.9 52.3 36.9 28.6 46.9 20.1 18.2 36.4 17.4 21.6 21.9 23.5 34.3 22.6 30.9 24.2 18.5 3.0 6.8 6.5 5.8 6.7 7.7 8.4 6.7 8.9 9.4 5.6 7.8 7.2 2.7 10.6 5.2 4.5 9.6 5.5 17.8 19.0 19.5 20.4 18.2 20.0 17.4 17.7 19.8 17.3 19.6 19.4 9.7 6.4 15.0 9.4 8.0 6.1 8.1 16.7 6.2 14.9 11.7 10.3 20.6 21.5 10.4 18.4 10.4 35.2 5.4 12.3 33.2 15.9 6.0 7.2 8.5 6.9 6.7 13.9 9.0 11.2 22.5 10.7 11.2 8.8 7.0 8.7 6.8 26.8 16.1 15.2 9.9 7.0 16.2 8.9 4.8 4.4 5.6 7.0 10.6 6.5 12.3 15.2 5.2 4.5 12.6 10.9 11.0 10.5 5.8 5.6 17.3 56.6 7.6 13.5 13.1 8.6 9.1 50.7 19.7 9.1 5.7 21.1 7.4 25.4 14.8 7.9 NFU1 "CGI-33, HIRIP5, NifU, NIFUC" ENSG00000169599 "NFU1 iron-sulfur cluster scaffold" Q9UMS0 2 69396113-69437628 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 189.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035826 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA035826: AB_2674803" "unprognostic (4.49e-3)" "unprognostic (5.62e-2)" "unprognostic (5.40e-2)" "unprognostic (1.84e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-3)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-1)" "unprognostic (2.21e-3)" "unprognostic (2.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.87e-1)" 66.8 46.3 36.8 22.5 39.3 33.4 56.8 40.0 56.0 35.6 37.4 51.4 31.3 35.9 51.9 27.9 35.3 29.0 110.4 37.5 40.9 64.2 39.5 31.8 30.0 40.2 39.7 38.0 39.9 43.3 45.1 38.1 41.4 34.3 38.1 56.9 41.2 36.5 140.8 22.3 33.4 33.1 39.9 31.0 43.8 34.6 39.0 22.8 41.9 120.2 29.5 44.8 31.1 42.0 59.3 59.2 56.1 55.5 70.4 75.4 61.6 61.0 62.0 59.0 47.8 114.7 56.9 42.4 30.0 57.0 85.6 25.4 63.7 64.2 79.5 77.8 62.3 43.5 38.2 102.0 70.1 73.7 59.2 58.4 37.2 67.5 41.2 56.0 65.6 41.8 80.1 41.8 99.1 11.9 39.1 119.0 53.9 62.9 64.3 42.6 85.5 15.6 83.5 57.6 45.9 34.3 35.2 32.2 92.5 57.6 40.8 49.4 67.8 71.3 47.1 52.2 80.8 53.8 48.4 23.1 54.2 74.7 55.8 20.2 13.6 25.5 15.9 18.6 15.6 21.7 16.3 18.9 12.4 25.1 16.9 18.6 4.3 18.0 28.5 25.0 24.8 12.3 36.8 39.3 40.0 56.0 37.5 40.9 40.2 39.7 41.4 39.9 39.0 42.0 30.6 32.1 22.5 9.8 37.0 16.2 35.9 96.7 21.1 23.9 33.2 29.6 92.3 37.1 42.6 38.6 12.5 113.9 34.1 34.6 189.8 56.9 111.0 40.0 27.1 34.9 53.3 25.7 15.4 60.9 70.5 30.9 20.4 25.3 58.3 21.6 33.5 32.0 82.6 18.5 18.8 47.7 57.0 35.8 24.0 34.2 34.8 30.2 39.2 10.3 66.8 55.6 46.4 21.1 27.1 50.3 39.7 36.9 25.4 28.8 56.3 163.0 58.9 33.4 46.0 36.9 44.1 82.9 60.4 18.8 14.9 61.3 33.3 42.7 46.3 35.4 NIPSNAP2 GBAS ENSG00000146729 "Nipsnap homolog 2" O75323 7 55951793-56000181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 266.5;skeletal muscle: 645.5;tongue: 784.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 226.9;Endometrial ciliated cells: 107.5;Proximal tubular cells: 106.8" "Cancer enhanced" "Detected in all" "glioma: 73.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 301.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063084 Enhanced Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA063084: AB_2684938" "unprognostic (6.88e-2)" "unprognostic (6.53e-3)" "unprognostic (8.20e-3)" "unprognostic (4.95e-2)" "unprognostic (5.79e-2)" "unprognostic (1.53e-3)" "unprognostic (5.95e-3)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (6.38e-3)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.02e-8)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (6.65e-3)" "unprognostic (3.59e-1)" 61.2 70.3 46.0 25.4 48.4 39.2 59.0 47.2 56.9 45.4 50.8 56.0 31.4 41.1 36.6 49.0 50.4 27.5 266.5 45.1 49.5 63.8 14.5 36.9 26.4 45.2 48.7 34.7 49.2 70.4 27.1 31.0 47.1 53.4 53.8 27.6 79.2 55.9 645.5 21.9 32.4 46.6 49.0 26.1 46.5 20.5 50.0 40.1 86.5 784.2 28.7 40.8 26.0 47.6 301.3 52.3 67.5 112.6 38.7 65.8 33.1 24.7 58.2 69.7 53.5 36.5 64.9 43.8 40.5 46.6 67.5 39.1 51.4 52.2 68.7 27.9 75.4 31.1 27.6 46.9 54.6 68.0 30.2 60.3 78.4 23.8 64.5 79.1 74.6 62.2 56.2 41.9 54.8 13.4 68.1 70.4 66.7 66.5 52.3 68.0 31.3 90.8 94.6 46.7 71.7 80.8 56.2 67.0 78.3 53.0 129.9 72.3 43.9 31.7 47.4 11.3 52.0 34.1 30.9 81.2 35.1 41.9 95.7 48.2 86.6 39.1 22.6 86.4 27.2 37.7 28.8 23.8 91.7 37.0 34.2 25.2 15.3 41.9 69.1 38.1 37.9 72.4 46.0 48.4 47.2 56.9 45.1 49.5 45.2 48.7 47.1 49.0 50.0 47.6 45.4 51.3 57.7 0.0 10.3 0.0 0.0 0.0 0.0 0.0 80.4 63.8 0.0 0.0 43.3 62.5 0.0 76.0 20.1 0.0 226.9 74.8 0.0 107.5 56.1 22.1 0.0 0.0 0.0 57.2 56.4 23.4 0.0 57.6 16.4 64.7 0.0 0.0 88.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 39.8 0.0 0.0 0.0 0.0 46.2 0.0 0.0 5.2 0.0 0.0 106.8 88.2 0.0 0.0 0.0 26.7 0.0 0.0 0.0 0.0 51.4 12.3 74.0 0.0 0.0 NIPSNAP3B FLJ11275 ENSG00000165028 "Nipsnap homolog 3B" Q9BS92 9 104764129-104777764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 20.4;tongue: 19.5" "Cell type enhanced" "Detected in many" "Adipocytes: 11.8;Cardiomyocytes: 21.6;Excitatory neurons: 10.7;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "REH: 3.0;SH-SY5Y: 2.1;THP-1: 2.2;U-266/70: 2.3" HPA042491 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042491: AB_2678023" "unprognostic (1.72e-2)" "unprognostic (1.47e-2)" "unprognostic (9.76e-2)" "unprognostic (1.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (8.36e-2)" "unprognostic (1.41e-3)" "unprognostic (3.55e-2)" "unprognostic (1.30e-1)" "unprognostic (4.25e-5)" "unprognostic (1.44e-1)" "unprognostic (3.72e-2)" "unprognostic (5.61e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (4.81e-2)" 6.6 5.1 1.8 1.1 1.9 0.7 4.3 1.2 2.2 2.3 1.6 1.1 0.5 3.1 3.4 1.0 1.9 1.3 12.8 1.9 2.0 1.5 0.5 1.4 1.5 1.5 1.5 3.3 1.9 1.0 2.7 3.0 1.6 2.7 0.9 2.5 1.4 3.6 20.4 1.3 1.2 1.6 1.2 2.0 1.1 1.0 1.8 0.8 2.0 19.5 1.8 0.9 1.5 1.5 0.0 0.3 0.4 0.1 0.4 0.4 0.7 0.1 0.2 0.2 0.1 0.3 0.3 0.8 0.1 0.2 0.0 0.0 0.2 0.1 0.2 0.0 0.5 1.4 1.2 0.1 0.4 0.2 0.4 0.4 0.1 0.3 0.0 0.5 0.1 0.7 1.2 0.0 0.0 0.2 0.6 1.2 0.2 0.0 0.2 3.0 0.0 0.1 0.1 0.0 0.9 2.1 1.2 0.0 0.1 0.2 1.1 2.2 0.1 0.2 0.4 0.2 0.1 2.3 0.8 0.2 0.0 0.2 0.0 2.8 0.0 0.6 0.0 0.1 0.1 0.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 1.8 1.9 1.2 2.2 1.9 2.0 1.5 1.5 1.6 1.2 1.8 1.5 11.8 0.0 1.1 2.0 8.5 0.4 1.5 0.8 1.2 4.0 0.9 1.7 21.6 0.0 0.3 3.7 0.0 0.8 0.1 0.0 5.9 0.7 0.0 2.2 2.0 3.4 1.2 5.9 10.7 0.2 0.2 3.9 2.6 1.2 1.3 2.5 6.1 0.3 6.2 0.0 9.8 0.3 4.1 0.9 3.9 0.9 2.5 3.0 0.0 16.9 4.1 1.2 0.0 4.5 1.1 0.2 0.0 6.8 2.3 0.3 0.0 0.4 3.2 0.5 0.0 2.0 3.7 0.8 1.1 1.7 0.9 0.8 1.1 0.8 0.2 0.2 NKX2-5 "CSX, CSX1, NKX2.5, NKX2E, NKX4-1" ENSG00000183072 "NK2 homeobox 5" P52952 5 173232109-173235311 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Atrial septal defect, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "heart muscle: 229.0" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 68.4" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 32.9;NTERA-2: 11.4;SK-MEL-30: 15.2;U-2 OS: 25.4;U-251 MG: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA065034 Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA065034: AB_2685409" "unprognostic (3.81e-1)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (9.57e-3)" "unprognostic (3.22e-3)" "unprognostic (6.63e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-1)" "unprognostic (2.31e-1)" "unprognostic (5.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.77e-2)" 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 229.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 34.9 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 5.0 1.7 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 7.6 32.9 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.2 0.2 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.1 0.5 6.3 0.0 15.2 4.2 0.0 0.1 0.0 5.9 25.4 7.8 20.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 68.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.1 0.0 0.1 0.1 0.0 0.7 0.0 0.0 NLRX1 "CLR11.3, NOD9" ENSG00000160703 "NLR family member X1" Q86UT6 11 119166568-119184016 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 43.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 15.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061516 Supported Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "Plasma membrane, Cell Junctions" "HPA061516: AB_2684548" "unprognostic (7.58e-2)" "unprognostic (3.71e-1)" "unprognostic (6.36e-2)" "prognostic favorable (2.47e-5)" "unprognostic (5.60e-3)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (8.80e-2)" "unprognostic (1.17e-1)" "unprognostic (3.49e-1)" "unprognostic (3.29e-1)" "prognostic favorable (2.59e-6)" "unprognostic (3.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.83e-2)" "unprognostic (4.22e-2)" 8.1 10.7 4.9 4.7 5.0 6.5 7.0 4.7 5.5 10.5 6.4 10.8 4.8 10.1 3.4 43.2 9.8 5.2 17.0 4.7 4.6 8.8 9.1 5.5 5.0 5.3 5.1 4.0 9.6 6.0 4.8 4.2 5.4 8.3 3.4 2.7 10.3 6.8 24.1 21.5 6.4 5.8 5.1 8.1 7.3 3.5 5.1 4.7 7.9 13.7 10.5 9.6 16.5 5.2 5.3 15.6 1.6 12.2 5.1 5.9 2.4 7.0 8.0 3.4 5.9 0.9 13.0 9.5 21.0 8.9 5.1 13.1 4.7 4.0 1.1 12.5 5.0 12.6 5.5 8.6 7.7 4.4 7.0 6.6 16.4 4.5 8.7 6.9 7.0 12.5 0.1 6.2 3.6 14.2 7.5 10.7 7.5 6.9 8.6 14.6 2.1 3.1 8.2 6.8 2.3 7.9 10.4 5.5 4.5 2.4 17.7 13.0 8.2 6.8 6.0 6.1 3.6 2.2 2.6 3.3 1.0 13.4 4.9 2.8 3.5 15.4 0.8 1.5 1.0 0.5 0.8 1.2 2.1 0.4 0.9 1.0 8.1 1.4 1.4 0.9 1.4 2.3 4.9 5.0 4.7 5.5 4.7 4.6 5.3 5.1 5.4 5.1 5.1 5.2 3.0 0.0 7.9 5.9 3.2 2.5 1.7 4.5 2.8 1.3 4.1 4.2 12.8 2.8 4.2 7.3 2.1 3.6 1.4 7.3 1.9 7.1 2.0 8.7 2.8 3.8 2.4 3.8 5.9 3.8 2.2 3.5 8.2 4.1 0.0 5.7 5.3 10.2 6.5 0.0 4.0 3.7 2.0 6.0 1.8 4.7 1.2 4.0 1.8 2.8 6.2 6.1 5.2 5.5 2.8 5.5 7.6 1.2 1.8 1.6 3.9 5.3 7.2 3.2 0.0 2.9 2.7 1.9 2.0 10.8 4.7 0.5 2.8 2.1 5.5 1.2 NMNAT3 PNAT3 ENSG00000163864 "Nicotinamide nucleotide adenylyltransferase 3" Q96T66 3 139560180-139678017 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 567.3;Alveolar cells type 2: 566.9;Club cells: 217.6;granulocytes: 278.8;Late spermatids: 223.3;Respiratory ciliated cells: 250.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039077, HPA057402" Approved Supported Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA039077: AB_2676336, HPA057402: AB_2683427" "unprognostic (9.45e-3)" "prognostic favorable (9.67e-4)" "unprognostic (2.29e-1)" "unprognostic (1.56e-3)" "unprognostic (2.33e-2)" "unprognostic (2.33e-1)" "unprognostic (2.77e-3)" "unprognostic (6.22e-2)" "unprognostic (9.69e-2)" "unprognostic (1.92e-1)" "prognostic favorable (7.29e-5)" "unprognostic (4.57e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (3.07e-1)" 7.5 7.4 17.7 4.9 26.7 19.3 8.3 46.5 45.4 6.7 8.2 6.9 9.2 9.4 8.1 5.4 13.6 5.4 11.6 21.5 10.9 9.2 6.6 4.3 4.8 8.6 5.3 20.1 12.0 8.9 5.5 2.2 15.1 6.5 7.5 30.6 9.3 5.5 29.6 19.0 7.8 5.6 2.5 5.4 5.6 11.3 14.6 3.0 7.6 20.3 5.3 5.5 6.8 50.1 9.2 3.6 4.0 4.6 0.9 0.9 5.0 3.7 0.4 0.6 0.5 5.1 6.4 5.9 10.8 0.7 4.3 4.5 3.0 1.2 0.7 5.8 5.3 31.4 9.1 6.9 2.4 5.6 5.5 1.4 7.8 1.0 1.7 9.3 0.5 3.6 5.0 13.1 0.6 6.2 5.3 4.6 9.0 16.5 3.7 4.4 4.5 4.3 1.2 6.3 9.2 5.4 9.2 4.8 3.3 7.3 12.6 15.6 5.6 5.7 12.6 7.2 5.5 23.1 11.0 4.2 3.8 9.0 5.4 11.4 3.6 2.2 2.8 3.4 1.9 2.7 2.4 2.4 2.8 4.5 3.4 3.6 7.0 4.0 3.4 2.9 1.6 1.7 17.7 26.7 46.5 45.4 21.5 10.9 8.6 5.3 15.1 2.5 14.6 50.1 5.5 567.3 566.9 34.9 1.9 4.1 6.3 6.6 6.2 2.7 8.2 7.1 9.7 8.6 217.6 9.2 4.2 0.4 0.8 2.3 11.7 3.3 128.2 2.1 2.4 38.8 6.7 27.1 37.2 3.1 0.2 38.3 3.1 1.7 278.8 9.7 2.5 2.7 2.0 1.7 26.0 6.5 8.2 4.1 2.9 223.3 7.8 31.8 7.2 12.2 1.8 12.3 0.0 46.8 16.9 0.8 2.9 6.4 0.7 6.1 3.5 16.1 250.6 18.5 6.6 13.2 3.8 67.1 3.5 4.4 9.7 0.1 21.5 5.9 10.6 4.8 NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.1;tongue: 384.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 344.3;Hepatocytes: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975" Enhanced Approved Mitochondria,Cytosol NA NA 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "CAB004975: AB_425908, HPA004829: AB_1079495" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favorable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" 26.0 16.5 12.8 11.8 16.0 15.0 13.7 11.2 21.7 16.4 34.9 25.9 17.2 11.0 16.7 16.8 10.7 15.0 137.7 16.1 11.5 57.0 116.4 13.2 16.5 10.3 12.0 10.1 17.8 55.6 9.6 12.7 9.5 18.3 27.8 12.9 26.6 18.2 239.1 10.4 16.1 20.6 9.3 11.5 31.2 6.2 15.8 26.8 31.1 384.0 17.2 17.3 9.3 15.1 15.4 12.6 30.5 59.6 44.0 50.3 9.9 17.5 39.8 24.8 20.8 19.0 30.4 18.5 21.5 43.9 22.3 16.6 120.5 5.4 27.4 31.1 33.6 24.0 70.7 23.8 27.5 50.2 43.1 37.9 17.5 16.3 18.6 42.6 56.3 22.7 21.4 81.3 60.0 15.1 55.8 35.8 6.4 0.1 15.2 54.7 73.8 70.8 58.0 15.5 44.2 37.7 62.9 1.4 46.7 6.9 47.7 58.3 23.2 29.5 28.3 12.0 8.3 36.1 45.1 26.5 7.1 68.8 22.1 12.5 18.2 16.0 16.7 23.0 17.1 12.0 17.1 15.5 32.0 12.0 15.5 14.7 2.9 23.2 24.7 9.1 22.2 19.3 12.8 16.0 11.2 21.7 16.1 11.5 10.3 12.0 9.5 9.3 15.8 15.1 12.0 54.5 37.8 60.7 19.6 11.5 9.5 19.0 13.1 17.9 9.6 6.3 344.3 38.6 27.0 27.6 35.5 8.7 20.4 34.4 27.4 14.4 16.7 18.5 16.6 19.2 19.9 34.9 124.8 10.7 2.3 27.2 23.9 25.1 25.2 26.8 21.0 314.3 25.0 6.7 110.6 22.6 20.3 40.6 11.9 4.6 14.9 19.8 14.2 45.9 25.9 12.5 35.0 77.9 63.4 9.5 16.7 19.2 20.0 11.7 23.6 21.7 18.1 12.8 0.0 14.0 20.1 4.0 1.4 17.6 8.1 2.1 20.9 18.8 28.9 9.9 NOL3 "ARC, CARD2, MYP, NOP30" ENSG00000140939 "Nucleolar protein 3" O60936 16 67170154-67175735 "Disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009208 Enhanced Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "CAB009208: AB_634091" "unprognostic (2.83e-2)" "unprognostic (1.63e-2)" "unprognostic (3.34e-3)" "unprognostic (1.07e-1)" "unprognostic (2.70e-3)" "unprognostic (2.83e-1)" "prognostic unfavorable (6.43e-5)" "unprognostic (5.74e-2)" "unprognostic (4.07e-2)" "unprognostic (1.83e-1)" "unprognostic (2.15e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.39e-2)" "unprognostic (3.65e-2)" "unprognostic (3.90e-2)" "unprognostic (1.48e-2)" 34.4 77.5 36.1 3.8 37.1 0.7 35.4 36.7 36.2 37.1 30.7 32.5 6.7 27.8 11.4 48.6 35.4 10.2 99.3 32.9 35.0 33.0 52.0 28.9 3.1 43.9 36.2 29.3 50.6 37.7 60.2 11.6 39.6 70.1 7.6 28.6 51.1 13.8 142.2 79.2 18.1 8.0 35.4 15.9 28.2 7.6 36.9 2.8 35.6 97.5 4.1 38.7 39.8 38.1 14.9 23.9 3.9 22.1 19.2 14.5 22.0 11.8 12.5 12.6 7.4 5.2 38.2 0.3 38.0 13.8 3.3 24.3 5.4 18.3 3.0 13.4 8.3 0.6 19.8 7.8 12.0 1.3 2.9 8.9 33.1 9.9 7.0 35.9 5.3 5.2 5.5 15.3 24.0 38.7 0.3 1.9 3.7 13.5 58.1 13.3 8.3 29.8 21.5 4.5 31.1 16.6 49.5 35.3 5.7 5.1 75.5 4.0 12.4 16.5 14.1 16.3 10.3 22.1 7.5 4.2 46.4 3.7 5.7 0.0 3.5 0.0 0.1 0.3 0.0 0.0 1.7 0.1 1.1 0.0 0.0 0.2 0.8 0.4 0.1 1.1 0.0 1.3 36.1 37.1 36.7 36.2 32.9 35.0 43.9 36.2 39.6 35.4 36.9 38.1 5.1 28.9 33.6 19.2 2.7 13.8 27.6 70.6 21.6 18.5 29.3 32.6 51.2 35.8 28.8 3.7 16.7 8.1 0.8 18.2 15.6 61.3 1.2 8.6 14.0 10.1 22.3 0.0 5.0 34.7 11.3 13.8 11.2 16.4 2.5 7.6 13.2 30.9 11.4 55.5 7.6 23.7 38.7 4.1 4.5 0.7 25.1 3.4 21.4 4.7 14.6 36.3 1.0 4.0 11.3 44.2 11.4 30.1 10.4 28.5 15.5 26.2 21.3 47.9 13.1 38.7 32.3 0.3 1.2 16.4 19.7 11.1 3.2 3.6 16.4 31.6 NOS1AP "CAPON, KIAA0464" ENSG00000198929 "Nitric oxide synthase 1 adaptor protein" O75052 1 162069691-162370475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 22.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 204.3;Excitatory neurons: 142.3;Horizontal cells: 67.3;Inhibitory neurons: 107.6;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 82.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.9;HaCaT: 3.1;HEL: 4.6" "Low region specificity" "Detected in all" "CAB018582, HPA030066, HPA055561" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB018582: AB_2251417, HPA030066: AB_2673294, HPA055561: AB_2682851" "unprognostic (7.04e-3)" "unprognostic (2.20e-1)" "unprognostic (1.79e-2)" "unprognostic (3.93e-2)" "unprognostic (1.58e-2)" "unprognostic (4.75e-2)" "unprognostic (2.07e-1)" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.54e-1)" "unprognostic (3.48e-1)" "unprognostic (1.71e-1)" "unprognostic (2.15e-5)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "unprognostic (5.08e-3)" 0.4 2.8 16.3 0.1 20.1 1.8 1.2 8.0 16.2 0.6 0.0 1.3 0.6 0.5 0.2 0.7 0.6 0.6 0.8 22.2 2.4 0.9 3.1 0.4 0.0 3.0 2.1 0.2 0.9 0.5 0.8 0.4 0.4 0.7 1.1 3.6 1.5 1.4 0.2 1.1 0.7 0.4 0.0 0.0 1.4 1.8 5.5 0.1 0.1 0.2 0.2 0.6 0.4 21.5 3.9 0.0 1.8 1.1 0.0 0.0 0.2 0.3 0.4 0.5 0.4 0.9 1.0 0.0 2.2 0.1 0.6 3.1 0.6 0.1 0.1 0.1 1.7 4.6 0.6 1.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.5 1.0 0.6 0.4 0.0 0.1 2.1 0.3 0.0 1.3 0.6 1.5 0.0 0.7 0.1 0.9 1.4 1.4 0.9 0.8 0.1 0.6 0.5 1.1 0.2 0.4 0.0 0.4 0.0 0.6 2.2 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.3 20.1 8.0 16.2 22.2 2.4 3.0 2.1 0.4 0.0 5.5 21.5 4.4 0.0 0.5 5.9 0.4 2.9 6.1 0.7 0.6 11.6 14.1 21.5 2.3 2.8 1.5 22.0 204.3 0.2 0.4 7.9 9.8 1.0 36.8 4.5 3.5 3.6 6.7 2.7 142.3 1.2 0.3 1.3 9.7 7.9 0.0 8.0 3.3 21.2 0.1 67.3 107.6 10.2 0.0 0.8 0.4 12.4 4.4 0.2 0.0 43.1 0.0 13.4 1.0 79.9 82.9 0.7 5.3 7.2 0.1 6.8 3.9 0.6 1.7 3.8 6.6 0.9 1.1 2.0 2.2 2.3 2.0 0.5 0.5 1.9 5.3 7.8 NPTXR ENSG00000221890 "Neuronal pentraxin receptor" O95502 22 38818452-38844028 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "brain: 280.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Excitatory neurons: 41.7;Inhibitory neurons: 50.4;Oligodendrocyte precursor cells: 19.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 280.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 23.3;SCLC-21H: 30.8;SiHa: 23.6;U-87 MG: 87.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001079 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 420000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" Nucleoplasm "HPA001079: AB_1078414" "unprognostic (6.29e-2)" "prognostic favorable (3.93e-4)" "unprognostic (6.82e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.55e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-3)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-2)" "unprognostic (9.22e-2)" "unprognostic (8.65e-2)" "unprognostic (2.77e-2)" 2.7 5.0 91.6 1.9 75.4 0.3 2.8 0.3 145.7 8.7 0.0 9.5 1.3 10.9 3.8 3.0 7.9 2.0 15.7 280.2 17.0 1.6 1.9 1.9 1.6 4.1 15.2 8.1 5.2 7.0 6.8 0.4 0.7 8.1 1.5 5.3 4.8 7.0 0.6 1.1 3.3 7.6 3.1 2.5 5.0 1.8 58.0 0.7 2.7 2.5 1.5 7.3 4.8 46.0 1.0 6.2 0.2 1.8 12.2 1.2 0.0 4.1 0.9 7.9 2.7 6.2 1.3 0.0 7.2 1.1 23.3 0.8 1.7 0.2 2.6 0.6 2.0 0.0 0.2 9.6 1.2 0.1 0.3 3.9 0.4 7.2 0.1 11.4 0.3 0.1 7.7 0.3 0.3 9.7 0.0 0.5 7.3 3.0 2.2 1.6 0.0 15.3 2.0 17.1 30.8 2.0 23.6 0.1 0.7 1.7 9.9 2.5 0.4 14.1 8.4 0.0 0.7 2.1 0.0 0.0 87.9 18.5 7.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 91.6 75.4 0.3 145.7 280.2 17.0 4.1 15.2 0.7 3.1 58.0 46.0 4.7 0.0 0.0 9.4 0.3 1.1 2.7 0.9 0.0 6.6 3.3 1.5 18.0 4.3 3.0 3.7 2.1 0.0 2.3 0.0 0.0 7.3 1.7 1.7 3.2 4.2 1.8 0.0 41.7 3.8 0.0 1.5 0.5 3.0 0.0 1.5 5.0 0.4 0.2 0.0 50.4 0.2 6.1 0.3 0.9 0.8 1.8 0.3 1.8 1.9 0.0 4.8 6.2 19.1 10.5 2.0 0.0 2.2 0.9 3.8 0.1 0.5 2.2 3.3 0.0 2.4 2.8 0.2 1.3 0.1 1.0 0.0 1.7 0.3 0.0 3.4 NT5M "dNT-2, dNT2, mdN" ENSG00000205309 "5',3'-nucleotidase, mitochondrial" Q9NPB1 17 17303335-17347663 "Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 13.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 17.6;Erythroid cells: 31.2;Horizontal cells: 16.8;Inhibitory neurons: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "JURKAT: 8.5;RPMI-8226: 6.3;U-266/70: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043777 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA043777: AB_10962842" "unprognostic (5.70e-2)" "unprognostic (3.20e-2)" "unprognostic (1.06e-2)" "unprognostic (2.59e-2)" "unprognostic (8.61e-3)" "unprognostic (1.24e-1)" "unprognostic (1.60e-1)" "unprognostic (1.61e-1)" "unprognostic (2.48e-1)" "prognostic favorable (8.42e-5)" "unprognostic (4.28e-5)" "unprognostic (2.27e-1)" "unprognostic (4.93e-2)" "unprognostic (3.89e-2)" "unprognostic (1.05e-1)" "unprognostic (7.93e-2)" "unprognostic (1.05e-2)" 1.1 0.6 6.3 0.2 5.9 4.7 0.9 6.4 7.9 2.2 4.6 2.8 0.4 2.1 0.4 0.9 1.6 0.4 7.1 5.6 5.8 2.2 1.0 0.8 0.3 6.2 6.1 1.9 1.1 1.8 4.5 0.2 6.4 1.8 0.1 0.5 0.8 0.7 13.3 0.8 0.8 0.4 5.7 0.9 1.1 6.8 7.3 1.1 0.8 4.6 0.2 2.0 1.1 6.4 0.3 0.7 0.3 2.9 1.7 1.9 1.2 0.6 0.2 0.2 0.4 0.0 0.2 3.3 1.8 0.0 0.5 0.0 0.1 0.1 0.0 2.9 1.8 2.3 0.1 0.3 1.7 0.6 4.3 1.4 1.5 0.3 1.1 0.6 0.0 8.5 2.0 0.0 0.0 0.8 2.8 2.6 1.8 1.0 2.5 2.1 0.2 6.3 1.0 0.0 3.6 5.9 1.0 0.1 2.6 2.1 1.0 0.9 0.0 0.9 1.0 0.2 0.8 9.3 1.3 0.5 0.5 0.4 2.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.3 5.9 6.4 7.9 5.6 5.8 6.2 6.1 6.4 5.7 7.3 6.4 1.1 0.0 0.5 11.1 0.5 1.7 2.1 0.1 2.2 5.5 3.4 6.1 7.9 1.5 0.6 9.2 2.1 1.0 2.6 0.4 17.6 0.3 0.9 0.3 3.3 1.7 1.2 31.2 7.6 0.6 1.2 2.5 1.1 0.9 0.0 5.2 0.7 1.3 1.5 16.8 13.2 0.8 0.0 0.8 0.6 4.4 0.6 3.4 0.0 3.7 0.3 4.7 2.1 4.0 5.4 0.0 0.1 1.2 2.3 3.2 0.1 2.9 0.0 1.8 0.0 7.4 1.8 1.5 6.0 1.8 0.4 0.5 2.3 3.2 0.5 1.3 NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "Nucleotide binding protein like" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 68.2;Inhibitory neurons: 74.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA029203: AB_10602810" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.28e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "prognostic favorable (3.64e-8)" "unprognostic (2.82e-2)" "unprognostic (6.60e-2)" "unprognostic (3.67e-3)" "unprognostic (1.56e-2)" 9.7 6.4 4.2 3.9 4.6 1.8 8.9 4.5 4.8 4.9 4.2 7.6 4.9 5.8 7.6 4.6 6.4 5.3 17.0 4.0 5.0 12.2 12.3 4.1 5.7 4.9 4.7 6.8 5.5 7.9 3.8 5.5 4.5 6.3 7.8 5.2 11.9 6.1 11.9 4.7 5.8 5.4 4.3 6.6 4.7 3.5 5.0 5.5 8.0 17.4 5.4 4.2 3.2 5.8 13.6 8.5 6.4 3.3 8.9 16.4 11.5 7.3 8.2 8.9 10.2 5.9 15.3 9.8 9.2 9.1 7.5 11.7 8.6 15.5 15.3 7.1 11.1 3.5 6.3 30.4 8.8 10.4 3.0 10.7 17.0 6.0 12.8 7.3 5.0 7.0 6.4 4.9 9.8 7.4 7.7 7.1 5.4 10.8 13.1 8.6 13.4 5.3 10.2 10.0 6.0 6.2 12.2 10.8 14.5 7.2 21.1 5.4 4.9 8.6 5.9 5.6 6.8 8.1 9.7 9.3 5.5 7.3 7.9 0.0 1.1 0.4 2.1 1.2 1.7 2.6 2.7 2.3 4.4 1.7 3.0 2.4 0.4 2.5 0.7 2.2 1.8 0.9 4.2 4.6 4.5 4.8 4.0 5.0 4.9 4.7 4.5 4.3 5.0 5.8 6.9 12.8 9.8 68.2 10.1 9.6 8.6 5.4 9.1 15.3 10.2 7.1 36.9 15.7 10.6 9.2 20.9 11.2 7.5 6.3 7.9 6.8 24.1 12.6 10.8 6.3 7.2 6.7 48.2 5.7 10.2 12.0 7.1 5.4 14.5 16.4 4.6 15.3 4.9 10.1 74.8 12.0 2.0 4.1 16.1 7.4 6.5 6.1 12.4 54.4 2.8 16.2 5.2 87.9 99.6 5.2 5.8 11.7 8.0 4.4 5.1 19.1 18.7 28.4 13.1 11.8 9.8 15.7 5.2 7.3 11.6 5.7 6.4 23.1 18.2 5.9 NUDT13 DKFZp586P2219 ENSG00000166321 "Nudix hydrolase 13" Q86X67 10 73110375-73131828 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040636 Approved NA No "Cluster 24: B-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA040636: AB_10960360" "unprognostic (3.75e-1)" "unprognostic (3.85e-1)" "unprognostic (1.07e-1)" "unprognostic (2.48e-3)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.33e-1)" "unprognostic (2.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-1)" "unprognostic (9.40e-2)" "unprognostic (5.07e-4)" "unprognostic (1.91e-1)" "unprognostic (3.82e-2)" "unprognostic (8.82e-2)" "unprognostic (2.92e-2)" "unprognostic (5.96e-2)" 1.9 3.2 1.4 1.9 1.7 2.4 2.0 3.4 2.0 1.7 1.3 2.6 2.9 1.7 3.9 1.6 1.9 1.8 4.3 1.6 1.3 4.3 6.2 1.5 2.4 1.4 1.4 1.8 3.1 3.0 1.7 1.5 1.8 2.0 1.8 2.9 2.1 1.0 4.2 3.0 2.5 1.1 1.0 2.5 2.9 2.4 1.8 1.5 1.9 2.1 1.5 2.4 1.7 2.2 4.7 3.3 5.3 6.6 3.2 2.7 1.1 4.1 3.6 2.1 2.3 8.7 9.6 2.3 2.0 2.5 3.4 5.4 0.5 3.8 2.1 1.7 9.3 6.4 5.9 4.9 0.3 3.5 2.5 2.0 4.1 2.7 1.5 5.6 1.6 4.1 5.5 3.5 2.1 2.2 2.1 5.0 2.0 3.0 10.5 4.7 0.9 0.1 2.9 2.1 2.3 3.4 2.0 5.4 1.9 2.2 3.0 2.3 3.1 1.8 7.1 0.7 1.6 2.5 3.1 3.1 5.0 6.5 1.7 0.0 1.1 1.1 0.7 1.1 0.8 1.3 0.5 0.6 0.8 3.7 0.9 1.0 0.4 2.2 1.6 0.3 1.7 0.4 1.4 1.7 3.4 2.0 1.6 1.3 1.4 1.4 1.8 1.0 1.8 2.2 1.9 6.4 2.0 2.6 1.9 0.9 1.9 2.8 0.6 1.1 1.6 1.7 6.2 1.5 2.2 3.7 4.2 3.6 0.4 1.1 3.9 1.8 5.5 2.9 1.3 1.8 1.2 1.3 4.7 0.7 0.9 1.1 1.5 2.7 0.0 1.8 0.4 3.7 1.7 0.0 5.1 1.7 2.0 2.9 1.0 5.0 0.9 1.8 0.0 5.6 2.8 0.9 2.1 4.5 8.1 1.6 3.3 0.7 0.7 1.2 2.5 6.2 5.3 1.9 0.0 2.3 1.4 2.9 0.9 1.4 1.4 1.1 0.8 2.3 1.3 1.1 NUDT16L1 "SDOS, TIRR" ENSG00000168101 "Nudix hydrolase 16 like 1" Q9BRJ7 16 4693694-4695859 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044186, HPA063605" Approved Approved "Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA044186: AB_10968571, HPA063605: AB_2685058" "unprognostic (1.35e-2)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-2)" "unprognostic (3.14e-1)" "prognostic favorable (2.79e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (6.12e-3)" "unprognostic (6.81e-2)" "prognostic favorable (1.02e-6)" "unprognostic (2.78e-1)" "unprognostic (1.47e-1)" "unprognostic (4.08e-2)" "unprognostic (6.81e-3)" 19.7 46.4 43.1 12.0 44.8 22.2 21.5 43.6 52.5 23.1 45.6 28.5 21.7 21.4 15.3 28.9 23.4 8.4 58.2 44.1 42.0 43.4 64.1 17.2 17.9 45.3 43.2 22.7 24.6 20.4 39.9 8.0 41.9 34.8 11.9 14.5 26.6 14.7 25.0 25.2 29.2 8.5 43.3 33.7 30.1 22.8 44.3 18.2 30.8 16.9 13.1 22.7 21.8 45.7 14.7 23.8 21.2 28.7 15.7 12.1 19.4 17.2 12.9 20.4 12.8 26.9 11.6 15.2 24.4 20.7 10.3 16.8 23.1 23.4 9.5 22.6 38.9 16.8 21.1 32.8 17.0 24.4 19.2 18.7 21.3 17.2 10.7 13.9 15.1 22.6 31.2 18.5 20.1 57.3 36.8 36.0 33.6 24.4 27.0 50.9 22.4 24.2 24.8 18.0 41.8 31.5 25.1 25.9 11.7 16.5 38.4 56.4 20.0 16.7 25.3 39.8 15.9 32.1 20.5 26.1 10.4 32.3 34.8 56.6 54.3 96.2 52.6 48.2 63.1 60.7 63.4 62.8 50.2 65.3 74.0 63.5 68.2 63.9 53.5 83.6 78.3 98.1 43.1 44.8 43.6 52.5 44.1 42.0 45.3 43.2 41.9 43.3 44.3 45.7 23.3 16.0 22.4 14.4 32.6 14.0 19.7 37.4 27.9 52.1 36.0 36.2 52.6 24.3 28.0 42.3 10.4 53.8 43.6 47.7 109.5 28.7 5.2 28.7 33.6 21.4 43.1 23.1 10.2 30.9 31.8 24.0 30.5 29.0 27.9 31.7 17.9 41.8 40.9 47.1 11.8 51.7 89.5 18.3 18.7 8.7 31.4 20.8 30.2 3.7 43.3 83.5 34.0 9.5 15.0 30.0 48.5 50.0 33.0 17.9 77.8 98.2 20.1 58.3 46.0 14.2 22.8 14.8 34.7 24.9 16.6 49.1 43.6 58.0 51.4 17.6 NUDT6 "FGF-AS, FGF2AS, gfg, gfg-1" ENSG00000170917 "Nudix hydrolase 6" P53370 4 122888697-122922968 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 37.2;Early spermatids: 36.7;Proximal tubular cells: 46.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039202, HPA066115" Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039202: AB_10795032, HPA066115: AB_2685620" "unprognostic (7.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (3.11e-1)" "unprognostic (3.84e-2)" "unprognostic (4.23e-2)" "unprognostic (2.36e-1)" "unprognostic (3.79e-1)" "unprognostic (1.07e-1)" "unprognostic (6.29e-2)" "unprognostic (6.91e-6)" "unprognostic (1.13e-5)" "unprognostic (2.32e-1)" "unprognostic (7.60e-2)" "unprognostic (7.98e-2)" "unprognostic (2.16e-1)" 4.9 10.7 8.2 2.8 9.4 2.2 5.3 5.8 10.6 4.2 6.6 7.7 4.4 4.1 7.1 3.3 6.7 3.6 13.0 8.4 8.2 19.4 27.3 3.2 3.9 6.0 7.3 4.2 4.0 7.4 6.4 3.2 6.1 3.7 6.2 8.3 5.2 4.3 10.0 4.2 3.7 3.5 5.9 4.5 3.3 7.1 9.0 4.8 7.3 10.9 2.3 3.2 3.2 7.8 5.4 7.9 11.5 10.3 10.3 10.7 4.1 6.1 8.1 5.3 7.3 3.4 12.1 5.6 4.5 3.3 11.7 2.7 5.1 4.8 5.4 13.5 3.4 5.0 7.6 9.2 3.8 10.4 3.0 6.6 2.1 4.6 4.0 9.8 7.0 9.7 12.8 13.8 9.0 6.3 14.5 11.2 4.3 20.8 9.9 4.9 14.6 6.4 12.7 3.2 6.1 7.6 6.3 8.5 12.5 13.3 5.6 8.3 4.4 12.8 6.7 11.2 5.6 15.4 12.9 10.7 7.7 15.4 5.8 0.0 2.0 0.0 1.5 2.8 1.9 4.0 2.0 2.6 4.4 1.2 1.5 1.7 0.3 1.3 2.5 1.7 2.3 1.8 8.2 9.4 5.8 10.6 8.4 8.2 6.0 7.3 6.1 5.9 9.0 7.8 7.0 16.0 7.8 10.7 2.0 0.9 3.1 9.3 4.6 12.5 4.7 6.9 5.3 4.3 5.4 5.5 0.0 16.4 1.3 4.1 37.2 6.2 36.7 8.9 7.4 5.4 7.2 3.0 8.9 5.6 3.7 5.3 5.6 3.4 1.3 12.8 4.6 21.3 8.7 15.2 9.6 6.0 6.1 4.6 2.0 6.1 6.2 5.0 5.4 4.7 1.5 14.0 0.0 13.6 10.8 4.7 5.2 9.1 3.8 1.2 2.5 46.2 10.4 11.9 0.0 6.3 5.0 28.5 3.7 3.9 1.8 4.0 3.3 20.8 10.1 2.1 NUDT7 ENSG00000140876 "Nudix hydrolase 7" P0C024 16 77722492-77742260 "Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Proximal tubular cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 49.7;U-698: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042042 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" Nucleoplasm "HPA042042: AB_10806232" "unprognostic (1.92e-1)" "unprognostic (1.17e-2)" "unprognostic (6.64e-2)" "unprognostic (5.95e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.84e-4)" "unprognostic (2.48e-1)" "unprognostic (4.05e-2)" "unprognostic (2.11e-1)" "unprognostic (2.46e-2)" "unprognostic (4.74e-2)" "unprognostic (4.52e-1)" "prognostic favorable (5.36e-11)" "unprognostic (1.19e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (3.42e-2)" 14.4 23.6 5.9 5.2 6.0 2.2 9.2 6.4 7.4 5.8 15.6 12.0 10.8 7.8 17.5 6.6 10.2 6.8 37.6 5.6 7.8 22.1 70.1 6.1 8.9 5.5 5.4 7.3 9.5 16.3 6.0 4.5 6.0 6.6 12.3 9.7 9.0 7.2 8.1 9.0 8.7 7.4 5.3 7.0 7.5 8.7 6.8 6.4 11.8 12.1 9.1 8.2 5.8 6.1 2.1 7.0 6.2 3.5 28.4 7.2 5.8 1.8 9.1 2.7 3.5 2.0 8.8 10.3 6.6 6.9 6.5 6.9 4.7 7.6 1.6 3.3 6.4 0.1 0.4 9.6 3.1 7.1 1.4 12.2 9.4 1.5 5.3 1.2 4.8 14.7 7.6 4.4 1.1 19.1 3.7 16.8 6.6 12.4 1.7 7.8 0.8 3.1 14.1 0.0 5.1 5.0 6.5 2.6 5.7 10.6 18.6 49.7 3.7 3.1 0.4 1.4 0.3 0.0 0.0 40.6 12.1 8.8 0.0 3.8 12.4 1.7 12.6 17.5 14.4 14.2 14.8 15.1 10.2 19.8 19.5 13.5 2.0 3.5 17.5 11.7 31.5 8.8 5.9 6.0 6.4 7.4 5.6 7.8 5.5 5.4 6.0 5.3 6.8 6.1 8.3 16.0 8.7 12.7 4.1 9.7 6.5 14.6 14.2 2.5 10.9 14.5 17.9 18.6 7.9 14.7 0.0 20.3 7.9 12.1 58.7 8.0 11.6 19.5 4.7 8.2 6.7 3.6 4.3 9.5 9.1 8.5 3.6 6.6 1.3 7.0 5.3 41.2 5.9 6.7 5.6 6.6 10.2 9.2 4.4 4.6 5.6 4.1 8.8 1.9 2.1 25.0 10.3 3.5 2.7 4.0 10.4 4.9 1.1 2.0 22.6 42.2 21.0 7.3 6.6 7.1 8.9 14.2 20.0 12.2 13.9 6.7 6.9 10.7 14.8 4.5 OBSL1 KIAA0657 ENSG00000124006 "Obscurin like cytoskeletal adaptor 1" O75147 2 219550728-219571859 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 337.3" "Group enriched" "Detected in many" 8 "Early spermatids: 1140.1;Late spermatids: 1994.5;Spermatocytes: 572.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.4;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 11 "dendritic cells: 1.3;granulocytes: 4.4" "Cell line enhanced" "Detected in many" "BEWO: 155.2;SK-BR-3: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036404, HPA036405" Approved Approved Centrosome NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "HPA036404: AB_10670437, HPA036405: AB_2675104" "unprognostic (2.36e-1)" "unprognostic (6.79e-2)" "unprognostic (3.86e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.27e-3)" "unprognostic (2.89e-2)" "unprognostic (9.89e-2)" "unprognostic (4.22e-3)" "unprognostic (1.25e-1)" "unprognostic (4.21e-3)" "unprognostic (7.00e-2)" "unprognostic (3.95e-2)" "unprognostic (3.62e-2)" "unprognostic (1.43e-1)" "unprognostic (3.15e-1)" "unprognostic (2.16e-1)" 52.3 117.5 25.0 9.7 24.3 3.1 53.5 24.4 32.2 74.6 34.4 44.6 9.4 78.0 22.5 17.7 84.6 28.8 90.8 26.1 27.9 110.1 43.9 38.6 9.6 30.3 29.1 337.3 120.6 49.5 74.9 45.8 24.8 63.1 5.4 14.9 62.9 44.2 64.1 38.3 22.5 20.9 25.2 31.7 48.0 40.5 29.7 6.9 148.9 30.2 4.6 41.2 36.7 22.3 34.2 22.7 40.9 85.8 27.7 20.4 155.2 25.3 36.8 31.5 29.0 20.0 52.2 0.2 51.6 34.7 30.5 34.4 31.9 19.0 6.5 0.3 56.2 74.3 23.0 102.1 20.9 1.9 0.3 55.3 15.4 7.3 12.1 56.1 3.4 0.1 31.3 0.7 22.7 84.6 0.1 21.3 97.8 9.7 23.1 37.5 36.3 0.2 57.4 31.9 18.1 61.3 28.6 150.9 59.2 102.8 14.0 63.9 8.6 33.3 35.6 10.6 10.0 0.2 0.2 0.3 19.5 0.2 33.7 4.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 1.3 0.0 0.0 25.0 24.3 24.4 32.2 26.1 27.9 30.3 29.1 24.8 25.2 29.7 22.3 10.4 9.6 20.4 45.7 1.1 8.4 22.8 11.7 19.9 35.8 27.0 38.7 52.4 27.1 10.0 53.3 2.1 64.7 2.5 1.5 52.8 15.9 1140.1 19.5 33.0 11.4 20.4 0.0 21.1 12.5 69.7 30.1 6.6 21.7 4.5 152.8 11.4 15.4 7.7 42.1 43.3 3.7 6.1 1.0 3.9 1994.5 77.0 3.4 14.2 9.4 0.7 87.0 0.0 23.1 3.1 7.6 2.0 74.1 0.1 8.8 7.1 20.3 7.8 11.6 13.1 29.9 27.0 572.7 57.0 4.3 6.7 86.5 1.4 114.0 3.3 10.2 OGDHL FLJ10851 ENSG00000197444 "Oxoglutarate dehydrogenase L" Q9ULD0 10 49734641-49762379 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 98.5;kidney: 121.8;liver: 80.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 30.4;Collecting duct cells: 29.5;Cone photoreceptor cells: 31.3;Distal tubular cells: 92.0;Hepatocytes: 55.3;Horizontal cells: 30.3;Proximal tubular cells: 84.7" "Group enriched" "Detected in many" 5 "liver cancer: 14.7;renal cancer: 44.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.3;RPTEC TERT1: 43.4;SH-SY5Y: 16.3;SK-BR-3: 16.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA043716, HPA052497" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli fibrillar center" "HPA043716: , HPA052497: AB_2681853" "unprognostic (9.05e-2)" "unprognostic (3.93e-3)" "unprognostic (5.30e-2)" "unprognostic (2.50e-1)" "unprognostic (3.70e-3)" "unprognostic (2.03e-1)" "unprognostic (1.46e-3)" "unprognostic (4.19e-1)" "unprognostic (2.07e-1)" "unprognostic (1.46e-2)" "unprognostic (1.52e-3)" "unprognostic (4.60e-1)" "prognostic favorable (1.21e-14)" "unprognostic (3.25e-2)" "unprognostic (1.85e-1)" "unprognostic (1.59e-3)" "unprognostic (8.38e-2)" 0.2 11.6 23.1 0.3 23.4 0.0 0.0 23.7 41.1 0.7 98.5 1.4 1.0 2.2 0.5 0.1 1.0 0.4 5.8 24.4 36.9 121.8 80.0 0.0 0.2 38.4 25.6 1.6 4.3 50.5 29.3 0.1 38.9 1.6 0.3 18.7 17.1 6.3 0.1 0.1 1.1 0.7 15.4 0.3 1.0 2.3 33.8 0.5 23.0 0.8 0.6 0.5 0.5 24.3 0.0 0.0 4.7 21.3 0.0 0.0 2.7 0.1 0.1 1.1 0.2 10.5 2.3 0.0 11.4 0.0 3.4 0.4 7.4 0.2 0.4 0.0 0.4 0.0 0.2 5.3 0.2 0.0 1.6 0.3 0.0 0.0 0.0 0.6 0.0 5.4 0.5 0.0 0.0 3.2 8.2 7.3 2.0 0.8 1.0 0.0 0.0 0.0 43.4 0.7 12.0 16.3 0.1 16.2 1.1 6.1 4.5 2.9 0.0 0.0 10.6 0.0 0.7 0.2 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 23.4 23.7 41.1 24.4 36.9 38.4 25.6 38.9 15.4 33.8 24.3 0.0 0.0 0.0 20.2 0.8 0.0 0.9 0.4 0.0 30.4 0.1 0.1 4.4 2.8 0.1 29.5 31.3 0.0 0.0 0.4 92.0 1.1 0.2 0.9 0.2 0.3 4.8 0.0 16.8 0.0 0.1 0.3 0.0 1.6 0.0 0.7 1.4 55.3 0.1 30.3 21.4 0.5 2.0 1.3 0.0 0.5 0.0 0.5 0.0 1.0 0.0 5.4 0.0 3.5 1.8 0.1 1.1 0.0 0.0 0.3 0.0 84.7 0.0 18.1 0.0 0.0 0.2 0.1 2.4 0.0 0.0 0.1 0.6 0.4 0.3 0.3 OSBP2 "KIAA1664, ORP-4, ORP4, OSBPL1" ENSG00000184792 "Oxysterol binding protein 2" Q969R2 22 30693782-30907824 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.7;retina: 160.8" "Cell type enhanced" "Detected in many" "Early spermatids: 135.4;Excitatory neurons: 132.8;Inhibitory neurons: 156.3;Late spermatids: 304.4;Oligodendrocytes: 182.8;Rod photoreceptor cells: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.9;HeLa: 146.4;hTERT-HME1: 38.2;SiHa: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021514 Uncertain Approved Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA021514: AB_1854813" "unprognostic (2.89e-1)" "unprognostic (2.04e-1)" "unprognostic (2.83e-1)" "unprognostic (6.94e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (1.38e-5)" "unprognostic (3.01e-1)" "unprognostic (2.57e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" "unprognostic (2.31e-1)" "prognostic favorable (3.79e-6)" "unprognostic (9.00e-2)" "unprognostic (2.68e-1)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" 1.4 11.8 6.2 2.8 14.4 52.7 1.5 17.0 20.5 1.6 2.1 1.7 7.5 2.0 14.6 3.7 2.0 3.0 12.2 8.5 4.4 2.6 1.0 1.6 2.3 9.6 9.8 1.6 5.0 9.3 20.9 4.6 10.0 2.3 1.7 160.8 2.9 2.4 2.8 5.4 5.6 1.2 1.8 4.8 3.5 28.7 21.3 0.6 3.2 3.2 1.3 4.4 2.1 15.1 7.1 15.4 1.5 6.7 1.0 5.8 1.6 1.3 3.1 4.8 4.8 14.0 3.9 12.5 5.7 1.9 1.5 4.1 6.2 0.6 3.5 6.7 1.8 41.9 146.4 2.7 0.9 0.2 2.5 0.3 16.8 11.8 38.2 1.6 12.1 4.8 26.7 0.5 11.0 7.8 1.3 4.5 3.8 3.3 13.8 3.5 0.5 0.7 0.6 2.7 16.7 6.8 39.2 4.1 0.4 2.9 4.9 2.2 8.8 3.4 18.1 3.2 6.8 3.2 4.8 2.3 13.3 0.0 2.7 0.0 0.7 0.4 0.5 1.1 1.0 0.5 1.0 0.4 0.6 0.6 1.0 1.1 0.7 1.0 0.9 0.2 0.7 2.0 6.2 14.4 17.0 20.5 8.5 4.4 9.6 9.8 10.0 1.8 21.3 15.1 1.2 0.0 3.1 37.9 0.2 5.2 0.9 0.4 0.6 93.2 1.3 0.8 11.2 2.8 1.0 1.8 81.3 0.2 0.3 1.3 1.9 1.8 135.4 1.6 0.5 2.8 7.2 91.3 132.8 1.5 0.2 1.6 2.0 1.6 0.0 3.2 0.4 0.1 0.2 18.5 156.3 2.8 0.0 0.3 1.8 304.4 2.5 1.7 1.8 8.4 0.4 31.4 0.0 35.7 182.8 0.8 5.2 1.9 1.4 1.2 0.7 0.8 1.3 619.5 0.0 1.1 2.3 48.6 4.4 1.4 9.5 0.3 0.5 1.2 1.2 1.3 OXA1L "MGC133129, OXA1" ENSG00000155463 "OXA1L mitochondrial inner membrane protein" Q15070 14 22766522-22773042 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003531 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 32: Non-specific - Translation" Mitochondria "HPA003531: AB_1079539" "unprognostic (4.04e-3)" "unprognostic (2.41e-2)" "unprognostic (3.39e-1)" "unprognostic (2.24e-2)" "unprognostic (7.25e-2)" "unprognostic (1.42e-2)" "unprognostic (1.08e-2)" "unprognostic (1.06e-2)" "unprognostic (1.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "prognostic favorable (4.82e-4)" "unprognostic (8.35e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (1.15e-3)" 77.7 90.7 27.6 40.8 28.5 71.9 67.6 31.4 28.8 59.4 47.1 72.9 66.3 55.0 48.1 76.6 55.8 49.6 147.2 27.5 29.6 70.8 108.6 54.8 70.0 31.3 29.1 71.2 98.0 105.3 27.5 38.0 31.1 45.0 57.7 41.9 64.2 44.8 234.9 69.3 58.9 46.1 29.1 62.3 83.9 25.0 31.6 63.6 54.9 272.5 75.5 61.3 60.4 31.1 89.3 121.3 48.8 82.1 146.7 217.4 94.4 64.0 138.1 94.3 107.9 91.1 96.4 167.0 86.4 75.0 73.0 121.0 103.0 126.3 90.0 67.6 65.4 79.1 73.2 329.7 165.5 150.9 88.4 211.0 137.6 75.4 114.9 114.7 273.3 93.8 62.2 124.0 103.4 130.0 91.8 51.3 53.2 118.5 150.0 92.9 87.2 128.3 117.9 103.4 35.1 67.0 94.6 205.7 129.7 58.4 89.2 122.7 86.2 52.7 62.2 98.5 75.4 94.0 84.7 78.1 41.6 83.6 60.0 11.9 68.1 18.5 29.5 71.6 36.0 51.0 42.5 37.4 95.1 54.4 47.4 35.6 15.1 41.7 58.5 26.9 55.8 53.7 27.6 28.5 31.4 28.8 27.5 29.6 31.3 29.1 31.1 29.1 31.6 31.1 30.6 48.1 44.0 7.8 83.7 69.5 61.1 89.0 92.8 31.0 52.1 46.5 118.0 72.9 62.1 29.5 10.4 72.8 32.5 48.9 74.3 85.2 10.2 20.4 40.3 58.6 40.7 64.3 6.8 161.3 113.0 47.6 66.8 23.1 80.4 56.5 64.2 102.9 143.4 18.5 7.5 75.3 38.7 148.1 76.8 13.3 57.2 85.6 51.6 3.7 133.4 22.9 74.2 4.5 8.0 86.3 69.7 36.9 84.2 45.6 101.4 116.0 42.6 38.3 39.5 39.4 43.0 31.8 28.4 112.9 67.3 57.2 57.9 70.6 112.1 74.9 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 243.7;Distal tubular cells: 187.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 238.7;SiHa: 319.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 52.7 15.8 30.4 16.6 34.9 13.3 18.5 23.9 32.7 13.5 15.9 19.2 8.3 14.9 17.6 26.8 12.4 15.2 245.9 36.2 27.1 53.1 1.3 8.0 21.7 19.5 21.4 13.8 5.3 48.6 14.7 5.0 20.0 25.5 21.1 23.6 18.9 29.8 28.5 23.1 12.8 36.6 19.3 11.0 34.2 13.2 25.7 76.8 27.3 42.6 25.9 15.1 13.8 24.5 35.3 1.6 27.9 33.6 84.7 45.0 0.1 62.1 38.9 50.3 30.4 5.7 23.5 91.2 15.0 47.5 25.8 20.5 77.5 55.9 58.5 78.5 9.1 63.9 238.7 11.9 36.8 125.8 20.9 42.7 15.3 49.3 82.2 24.6 46.4 81.6 13.3 114.0 58.1 4.5 105.5 6.1 6.4 0.0 24.5 82.8 78.9 68.7 41.7 2.9 27.9 28.8 319.5 0.3 38.3 2.5 0.4 27.4 28.3 39.7 51.9 68.6 50.6 18.6 16.5 3.6 59.9 90.9 30.9 1.4 1.4 4.7 11.6 1.5 13.8 10.0 11.5 12.7 6.3 7.5 13.6 10.9 0.4 11.3 2.5 2.4 21.5 6.6 30.4 34.9 23.9 32.7 36.2 27.1 19.5 21.4 20.0 19.3 25.7 24.5 8.4 6.4 9.2 37.5 19.2 14.8 11.7 12.4 17.6 14.1 18.8 14.2 243.7 7.2 14.3 11.0 2.1 7.0 18.3 5.0 187.9 5.4 19.1 11.7 18.8 9.8 13.2 23.1 71.5 0.7 11.9 21.3 20.4 31.2 9.5 8.7 6.8 0.3 38.2 13.5 84.2 18.6 12.2 1.3 7.0 8.6 6.2 5.2 16.0 26.2 4.4 11.8 10.3 66.4 46.8 4.8 5.3 7.5 31.3 12.1 2.9 27.4 5.6 21.6 13.1 9.7 24.6 35.6 19.7 27.6 21.6 6.8 26.6 8.6 18.1 9.0 PACRG "FLJ32724, Glup, HAK005771, PARK2CRG" ENSG00000112530 "Parkin coregulated" Q96M98 6 162727132-163315492 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.7;testis: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 310.9;Excitatory neurons: 124.3;Inhibitory neurons: 174.9;Late spermatids: 369.8;Respiratory ciliated cells: 118.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 6.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066293 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA066293: AB_2685652" "unprognostic (3.06e-2)" "unprognostic (1.81e-2)" "unprognostic (1.59e-1)" "unprognostic (1.56e-2)" "unprognostic (2.48e-1)" "unprognostic (1.84e-1)" "unprognostic (6.26e-4)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.34e-1)" "unprognostic (8.31e-3)" "unprognostic (1.48e-1)" "prognostic favorable (2.55e-6)" "unprognostic (1.00e-1)" "unprognostic (3.68e-2)" "unprognostic (8.35e-2)" "unprognostic (2.93e-3)" 0.8 2.5 13.6 1.1 15.2 5.7 2.0 5.9 14.2 2.3 13.2 1.2 1.4 5.3 9.7 3.0 35.7 5.1 13.0 11.9 12.5 10.2 4.8 3.8 1.4 15.1 15.7 4.2 4.3 2.0 23.7 0.4 10.9 3.4 2.4 7.5 2.2 3.6 2.1 4.6 0.8 2.1 9.4 1.8 2.3 29.5 13.5 0.7 4.0 1.3 1.0 4.4 0.9 24.2 0.5 1.7 0.7 1.0 0.0 0.6 1.2 0.4 1.6 0.0 0.3 3.5 0.4 3.2 0.4 0.0 0.3 1.4 0.8 0.0 1.7 0.0 1.1 0.0 1.9 0.0 0.0 0.4 0.5 1.0 0.0 0.5 0.0 0.6 0.0 1.1 0.5 0.7 0.3 0.1 0.2 1.2 0.0 2.8 2.9 0.6 0.0 0.0 3.6 3.6 6.9 3.1 0.0 0.0 0.0 0.2 0.0 1.1 1.2 0.7 0.3 0.0 0.2 1.3 0.5 1.2 0.3 0.8 1.3 2.3 0.7 0.7 0.7 0.2 0.5 0.3 1.1 0.4 0.1 0.6 1.4 0.6 2.5 0.0 0.1 0.5 0.5 0.2 13.6 15.2 5.9 14.2 11.9 12.5 15.1 15.7 10.9 9.4 13.5 24.2 0.3 0.0 1.7 61.0 0.1 0.3 4.2 8.7 2.8 1.3 1.3 3.0 41.0 0.0 8.9 5.5 8.4 0.1 0.0 0.1 54.8 3.4 310.9 67.0 3.1 1.2 6.6 0.0 124.3 7.1 0.1 1.2 0.0 1.9 0.0 0.7 0.7 3.9 0.1 0.0 174.9 0.3 10.2 0.6 0.3 369.8 3.7 0.4 0.0 11.2 0.0 6.0 0.0 59.3 20.0 1.6 1.2 2.6 0.1 3.2 0.0 6.3 118.4 8.1 0.0 1.1 2.2 53.4 6.1 1.1 0.3 0.3 0.3 2.9 0.4 2.7 PACSIN1 SDPI ENSG00000124507 "Protein kinase C and casein kinase substrate in neurons 1" Q9BY11 6 34466061-34535229 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 149.3;retina: 64.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 76.1;Cone photoreceptor cells: 81.3;dendritic cells: 24.9;Excitatory neurons: 49.9;Horizontal cells: 69.0;Inhibitory neurons: 47.6;Rod photoreceptor cells: 89.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.8" "Cell line enhanced" "Detected in some" "MCF7: 12.1;RPMI-8226: 14.0;T-47d: 21.5;U-266/84: 16.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009929, HPA028852, HPA055491" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" "CAB009929: AB_2268057, HPA028852: AB_10602812, HPA055491: AB_2682834" "unprognostic (3.33e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.72e-2)" "unprognostic (2.47e-3)" "unprognostic (2.14e-2)" "unprognostic (2.65e-1)" "unprognostic (1.74e-1)" "unprognostic (6.63e-2)" "unprognostic (3.95e-4)" "unprognostic (9.12e-2)" "unprognostic (3.02e-2)" "unprognostic (4.18e-2)" "unprognostic (9.90e-2)" "unprognostic (5.50e-2)" "unprognostic (9.33e-2)" 0.2 0.7 40.9 1.2 72.9 0.8 0.2 0.0 149.3 0.3 0.0 0.8 0.5 0.5 0.1 0.1 0.6 0.3 5.4 64.4 0.0 1.4 0.2 0.2 3.6 58.8 10.0 0.6 5.1 1.7 6.3 0.0 55.4 0.7 0.2 64.3 1.0 0.4 0.2 0.3 1.4 0.1 0.0 1.3 1.3 0.8 3.9 1.3 0.2 0.1 2.2 0.4 0.3 59.5 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 4.5 0.8 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 1.1 0.1 0.0 12.1 0.7 0.0 2.8 0.1 0.1 0.1 0.0 14.0 0.0 0.4 4.2 0.3 0.0 2.2 0.0 0.4 21.5 2.4 0.0 0.0 0.3 0.0 0.0 3.5 16.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.6 0.0 15.8 0.0 0.1 40.9 72.9 0.0 149.3 64.4 0.0 58.8 10.0 55.4 0.0 3.9 59.5 0.2 0.0 0.0 2.3 0.3 0.0 0.1 0.0 0.0 76.1 0.2 0.1 4.5 0.0 0.0 0.0 81.3 0.1 24.9 0.1 0.0 0.3 0.2 1.3 0.2 0.6 0.0 0.0 49.9 0.7 0.0 0.1 0.5 2.0 0.0 0.2 0.0 0.0 0.0 69.0 47.6 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 6.5 0.0 12.7 1.0 1.0 2.0 0.1 0.0 0.0 0.2 0.1 0.0 2.3 0.0 89.4 0.0 0.2 0.2 0.4 1.7 0.0 0.0 0.0 0.6 0.1 0.1 0.1 PACSIN3 SDPIII ENSG00000165912 "Protein kinase C and casein kinase substrate in neurons 3" Q9UKS6 11 47177522-47186443 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 161.8;skeletal muscle: 480.9;tongue: 279.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Extravillous trophoblasts: 60.6;Muller glia cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039480, HPA043904" Approved Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA039480: AB_2676531, HPA043904: AB_2678725" "unprognostic (1.75e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (6.89e-2)" "unprognostic (4.66e-2)" "unprognostic (8.17e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.09e-4)" "unprognostic (3.86e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-2)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" 14.4 66.5 19.6 4.5 28.2 0.4 18.4 24.5 20.9 33.3 18.8 50.2 4.7 33.5 11.4 52.6 29.1 7.2 161.8 18.0 19.4 14.8 43.6 15.9 2.0 33.8 27.5 23.2 33.1 11.0 6.2 16.1 32.1 35.2 2.7 4.5 40.8 20.6 480.9 41.4 11.3 21.2 25.0 4.5 33.5 4.5 25.4 2.0 24.5 279.4 5.2 21.5 31.8 39.0 56.4 27.1 12.5 51.5 10.3 10.2 59.8 19.4 24.6 33.9 19.1 40.8 7.3 0.3 5.9 9.2 23.0 90.0 23.7 40.2 13.0 8.7 44.8 8.4 105.5 91.7 19.9 2.0 8.4 28.2 52.3 17.9 28.3 27.2 15.3 15.2 18.4 0.7 13.9 106.7 0.7 40.8 15.5 43.7 58.7 33.1 48.0 9.0 14.3 49.3 0.3 42.6 28.2 17.9 24.6 24.6 127.3 6.9 6.9 57.6 62.5 7.5 47.1 10.1 4.4 5.3 18.6 19.2 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 19.6 28.2 24.5 20.9 18.0 19.4 33.8 27.5 32.1 25.0 25.4 39.0 6.1 0.0 8.1 4.9 0.3 35.9 29.1 25.1 30.7 0.7 32.2 24.3 112.0 38.6 18.1 5.5 0.0 31.0 0.6 0.2 9.8 37.7 0.0 3.1 8.4 7.8 0.0 2.7 0.8 15.5 60.6 12.6 9.7 6.2 0.0 3.0 8.6 33.1 6.0 0.0 1.1 0.2 14.2 1.6 4.6 0.4 16.1 1.0 17.8 2.8 0.0 63.6 0.0 0.0 9.5 41.0 0.0 12.4 2.6 56.8 1.5 24.3 5.0 3.2 32.9 18.5 25.4 0.2 7.5 39.7 29.8 18.3 0.7 4.8 1.4 29.8 PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 181.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.0;Early spermatids: 95.1;Hepatocytes: 67.1;Proximal tubular cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 15.8;SCLC-21H: 23.1" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA046784: AB_2679804, HPA072371: AB_2686514" "unprognostic (8.70e-2)" "unprognostic (8.20e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.17e-5)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (9.67e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.96e-12)" "unprognostic (1.63e-2)" "unprognostic (3.87e-1)" "unprognostic (1.21e-2)" "unprognostic (4.61e-2)" 2.4 1.6 131.5 1.8 159.1 1.3 4.5 108.3 176.8 3.1 66.3 3.8 3.7 2.9 1.8 6.1 7.2 1.1 23.0 94.7 116.5 10.3 18.1 2.7 2.1 134.9 136.6 11.5 54.2 6.0 2.2 0.6 143.0 4.8 3.7 27.7 37.9 3.5 48.5 16.4 2.7 1.7 132.8 2.2 10.5 2.2 130.3 2.4 11.6 26.7 4.6 2.8 4.0 181.5 2.5 0.6 1.0 3.6 0.4 0.5 4.4 0.3 0.1 0.3 0.2 0.9 1.0 3.2 0.6 0.0 2.4 2.0 6.1 3.7 1.2 1.7 5.0 3.1 0.4 0.1 1.6 0.8 0.2 0.6 3.3 0.2 3.6 0.9 0.6 7.2 5.5 3.0 0.2 3.2 1.0 1.7 2.6 5.8 2.3 0.0 10.5 15.8 1.9 1.7 23.1 1.3 2.6 1.7 1.1 5.5 7.5 0.2 0.1 0.3 1.9 1.9 1.0 6.1 5.5 3.9 0.2 1.1 0.5 0.5 0.3 0.5 1.0 0.4 1.2 2.5 1.3 1.0 0.4 2.6 2.1 1.9 0.2 0.8 0.4 2.3 0.6 0.6 131.5 159.1 108.3 176.8 94.7 116.5 134.9 136.6 143.0 132.8 130.3 181.5 3.3 3.2 4.5 5.2 9.9 7.8 7.0 4.0 5.7 11.3 14.8 8.8 86.0 12.8 2.7 7.3 6.2 3.2 13.2 2.7 21.5 4.9 95.1 18.4 3.9 3.9 41.5 15.6 4.2 41.3 9.2 4.7 11.2 17.5 1.3 7.5 7.1 67.1 1.9 6.7 4.6 6.3 14.2 3.2 1.6 30.0 5.3 2.6 14.2 2.8 2.4 12.3 4.1 2.5 31.9 10.4 4.0 5.3 29.9 9.4 1.3 56.9 15.5 43.3 0.0 9.3 4.0 32.9 7.7 17.3 20.0 6.3 4.7 4.3 8.1 6.0 PANK1 "MGC24596, PANK, PANK1a, PANK1b" ENSG00000152782 "Pantothenate kinase 1" Q8TE04 10 89579497-89645572 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 45.2;liver: 109.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 37.5;Distal tubular cells: 70.5;Hepatocytes: 149.8;Proximal tubular cells: 53.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.00e-1)" "unprognostic (2.19e-1)" "unprognostic (2.02e-2)" "unprognostic (1.09e-2)" "unprognostic (6.71e-2)" "unprognostic (6.97e-2)" "prognostic favorable (1.50e-4)" "unprognostic (1.59e-1)" "unprognostic (1.38e-2)" "unprognostic (1.61e-1)" "unprognostic (4.55e-4)" "unprognostic (4.61e-2)" "prognostic favorable (1.55e-10)" "unprognostic (3.49e-2)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" "unprognostic (6.64e-2)" 2.1 4.6 2.8 2.1 3.1 0.5 2.5 7.2 4.2 5.3 9.7 13.9 20.4 1.8 3.8 5.3 3.0 1.7 8.6 3.1 2.7 45.2 109.7 2.2 1.8 3.5 3.4 2.3 1.8 6.5 1.5 2.7 3.8 1.9 17.3 2.0 2.1 2.3 11.4 9.6 17.2 2.3 2.0 1.6 4.6 2.8 4.0 5.2 10.4 28.0 2.6 1.9 3.5 2.8 8.0 5.2 28.1 19.4 14.9 10.8 14.2 4.6 5.0 4.3 5.7 8.2 8.1 5.8 3.0 3.6 3.2 7.9 12.9 2.9 4.6 2.0 5.7 3.9 5.6 16.2 4.4 12.3 2.1 6.6 12.7 6.5 5.1 9.2 5.1 4.9 6.8 0.7 6.3 6.2 13.6 12.5 22.1 21.0 3.1 11.9 5.6 3.8 13.2 3.8 8.7 10.4 5.8 6.9 4.6 16.6 7.5 8.9 2.2 2.6 2.5 5.2 5.7 6.5 12.7 7.2 3.4 9.7 1.8 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.1 2.8 3.1 7.2 4.2 3.1 2.7 3.5 3.4 3.8 2.0 4.0 2.8 0.6 6.4 3.7 7.8 1.6 2.3 0.7 2.2 1.8 4.7 2.1 2.0 12.9 10.0 2.5 11.0 2.1 4.7 0.5 37.5 70.5 1.1 0.5 2.5 2.6 1.7 11.4 7.8 21.1 0.7 4.5 1.8 2.0 3.3 0.0 8.4 3.3 149.8 2.4 13.5 32.1 14.8 0.0 3.8 0.7 0.7 1.2 2.2 0.0 7.5 0.4 1.0 0.0 12.1 3.0 0.1 17.9 2.2 1.4 0.5 31.4 53.2 1.5 1.3 0.0 2.2 5.1 0.7 0.8 5.6 2.8 1.8 1.8 1.4 25.1 0.5 PAQR9 FLJ41938 ENSG00000188582 "Progestin and adipoQ receptor family member 9" Q6ZVX9 3 142949164-142963674 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 13.5;retina: 9.6;testis: 20.4" "Cell type enhanced" "Detected in some" "Early spermatids: 42.1;Erythroid cells: 28.2;Hepatocytes: 18.4;Late spermatids: 98.3;Syncytiotrophoblasts: 36.5" "Cancer enriched" "Detected in single" 15 "liver cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.0;AF22: 1.0;U-266/70: 3.3;U-266/84: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052798 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA052798: AB_2681955" "unprognostic (4.13e-2)" "unprognostic (2.54e-1)" "unprognostic (2.81e-1)" "unprognostic (3.09e-2)" "unprognostic (1.21e-2)" "unprognostic (5.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.56e-2)" "unprognostic (1.23e-2)" "unprognostic (1.09e-1)" "unprognostic (6.91e-2)" 0.0 0.0 1.9 0.0 1.7 5.2 0.0 0.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 2.3 1.5 0.0 13.5 0.0 0.0 1.1 1.9 0.0 0.0 0.2 0.9 0.2 1.1 0.0 0.0 9.6 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.0 0.0 20.4 3.3 0.1 0.0 1.4 0.0 0.1 0.0 2.0 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 0.9 5.5 2.3 1.5 1.1 1.9 1.1 0.2 3.3 2.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 5.8 0.0 0.0 6.7 1.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 42.1 0.7 0.0 0.2 0.0 28.2 0.8 0.0 0.1 0.3 0.0 0.2 0.0 1.0 0.0 18.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 98.3 1.2 0.0 0.0 0.0 0.0 1.7 0.0 1.0 0.2 0.1 0.0 1.9 0.0 0.0 0.0 0.1 0.0 6.8 0.0 0.0 0.1 2.6 5.4 0.0 0.1 36.5 0.0 0.1 0.0 0.0 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PATJ "Cipp, INADL" ENSG00000132849 "PATJ crumbs cell polarity complex component" Q8NI35 1 61742477-62178675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 86.6;Alveolar cells type 2: 60.6;Club cells: 39.0;Collecting duct cells: 57.0;Endometrial ciliated cells: 55.7;Glandular and luminal cells: 98.3;Pancreatic endocrine cells: 47.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 75.0" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 36.3;RPTEC TERT1: 30.3;RT4: 33.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 72.3" "HPA066352, HPA066960, HPA069079" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "Centriolar satellite, Cytosol" "HPA066352: AB_2685663, HPA066960: AB_2685755, HPA069079: AB_2686079" "unprognostic (1.81e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (7.96e-2)" "unprognostic (7.60e-2)" "unprognostic (1.88e-1)" "unprognostic (9.90e-2)" "unprognostic (3.39e-3)" "unprognostic (2.99e-2)" "prognostic favorable (1.47e-5)" "unprognostic (3.05e-3)" "unprognostic (6.72e-3)" "unprognostic (2.21e-2)" "unprognostic (2.43e-1)" 3.4 7.2 6.8 3.6 5.4 3.5 18.1 75.0 5.3 8.4 25.3 12.2 8.9 5.8 26.5 19.3 8.3 7.1 45.2 3.8 9.2 27.5 12.4 10.0 2.9 12.8 9.0 6.8 12.4 20.0 10.9 3.5 14.2 12.3 11.1 15.8 20.0 7.9 45.4 22.4 9.3 3.5 11.5 3.1 10.2 5.1 9.1 4.0 13.1 16.1 6.2 7.9 13.2 9.5 36.3 7.0 2.3 3.2 1.3 3.3 29.5 2.1 2.8 2.2 3.0 12.5 13.2 0.2 9.1 4.4 18.7 21.1 5.1 18.9 3.8 3.5 8.8 0.2 10.4 11.3 2.9 0.1 0.2 1.2 19.7 3.7 8.0 5.3 1.2 0.0 0.0 0.0 1.9 12.6 0.1 0.1 12.0 16.4 1.9 0.1 2.8 5.2 30.3 33.4 6.1 2.0 8.8 29.4 7.7 23.7 23.7 0.3 0.3 1.8 4.3 0.2 4.2 1.4 2.7 4.8 1.7 0.0 0.5 0.4 0.0 7.2 1.2 0.1 2.3 1.2 2.0 1.7 0.0 1.1 2.6 1.7 0.6 2.6 0.1 0.2 1.9 0.6 6.8 5.4 75.0 5.3 3.8 9.2 12.8 9.0 14.2 11.5 9.1 9.5 6.4 86.6 60.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 35.0 29.8 0.0 0.0 39.0 57.0 0.0 4.3 3.8 0.0 5.9 37.6 0.0 55.7 8.6 1.6 0.0 0.0 0.0 26.4 0.7 5.5 0.0 98.3 1.3 14.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 2.7 0.0 0.0 35.7 27.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 26.4 10.3 1.7 0.0 0.0 PCBD1 "DCOH, PCBD, PCD" ENSG00000166228 "Pterin-4 alpha-carbinolamine dehydratase 1" P61457 10 70882280-70888565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation" "Activator, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 429.5" "Cell type enhanced" "Detected in all" "Distal tubular cells: 453.9;Hepatocytes: 603.7;Proximal tubular cells: 877.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 527.8;Hep G2: 527.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037575, HPA061723" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA037575: AB_10671761, HPA061723: AB_2684594" "unprognostic (1.02e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (3.69e-1)" "unprognostic (5.39e-2)" "unprognostic (4.80e-3)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (2.40e-2)" "unprognostic (2.95e-1)" "unprognostic (5.63e-2)" "unprognostic (3.38e-2)" "unprognostic (9.26e-2)" "unprognostic (1.74e-1)" "unprognostic (5.76e-2)" "unprognostic (7.43e-3)" 77.3 102.9 115.0 31.0 111.8 21.8 67.9 111.9 140.7 58.0 114.1 83.9 54.4 48.2 91.2 54.3 111.5 47.4 152.3 109.3 136.9 165.1 429.5 57.9 31.1 125.4 138.5 64.2 174.9 135.1 61.5 33.4 139.4 73.8 88.3 48.6 49.9 78.4 109.7 25.7 64.0 75.6 119.7 25.6 84.8 20.0 131.8 25.8 86.3 109.1 35.8 69.3 39.2 118.9 158.3 374.3 21.4 223.8 80.9 76.0 29.4 50.0 84.5 77.7 61.6 527.8 270.3 32.2 141.4 56.3 57.9 101.7 138.9 81.3 53.2 86.2 251.9 28.6 57.5 527.1 84.9 28.5 99.2 74.1 88.5 76.5 35.8 114.1 212.3 19.9 57.1 2.8 55.2 270.2 3.5 94.7 30.1 420.5 346.0 15.1 29.7 103.6 328.6 164.7 94.0 158.8 41.5 277.1 111.5 59.9 81.1 53.8 86.2 12.7 102.9 18.9 123.8 1.1 6.7 1.1 68.3 93.1 19.5 0.2 24.8 8.7 19.6 47.1 15.3 25.7 25.8 28.3 49.6 10.9 8.4 17.1 1.6 19.6 34.4 35.8 41.1 18.7 115.0 111.8 111.9 140.7 109.3 136.9 125.4 138.5 139.4 119.7 131.8 118.9 25.5 41.7 91.5 8.5 25.9 49.8 169.1 88.2 103.0 39.0 197.9 249.6 151.5 138.7 86.0 187.6 6.2 124.6 18.5 113.8 453.9 185.0 2.3 138.7 49.3 40.8 176.4 36.2 4.9 169.9 81.6 82.2 86.6 175.3 31.1 64.6 37.9 603.7 180.3 35.3 8.5 313.3 65.1 79.9 55.7 11.2 67.4 73.1 78.2 5.6 68.0 153.0 22.6 9.0 4.6 154.8 164.7 95.5 35.1 212.7 232.1 877.7 78.4 33.2 85.5 57.2 63.3 4.4 12.3 147.8 45.7 77.6 32.6 95.9 230.2 187.5 PCBD2 "DCOH2, DCOHM" ENSG00000132570 "Pterin-4 alpha-carbinolamine dehydratase 2" Q9H0N5 5 134905120-135007959 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 49.4;tongue: 42.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036428 Uncertain Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA036428: AB_10670103" "unprognostic (3.70e-2)" "unprognostic (3.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (4.22e-1)" "unprognostic (6.43e-2)" "unprognostic (4.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.57e-2)" "unprognostic (6.34e-2)" "unprognostic (9.32e-3)" "unprognostic (1.50e-1)" 5.3 7.7 7.3 4.8 8.5 7.6 6.0 7.8 7.6 4.3 11.0 6.1 9.5 4.2 4.1 8.3 5.7 4.6 17.1 6.4 7.5 10.2 11.9 4.9 5.9 8.7 7.7 5.1 8.0 13.0 3.8 3.5 8.0 5.4 7.0 9.9 9.6 3.8 49.4 9.2 8.1 3.6 6.8 5.8 8.2 3.2 8.1 5.5 9.6 42.7 6.1 4.5 4.9 10.8 7.5 7.2 9.4 6.9 5.7 5.2 5.2 6.0 5.2 3.8 3.8 12.0 17.5 8.7 8.8 4.4 6.1 6.5 5.6 5.9 3.4 12.3 3.1 6.0 9.5 7.1 5.4 7.1 3.6 3.4 7.1 3.6 7.6 5.1 4.3 7.7 7.7 12.2 6.9 13.0 7.5 12.3 5.1 11.5 6.9 10.9 8.4 9.7 8.1 7.4 7.2 9.2 10.4 6.0 9.1 7.1 13.0 9.4 5.9 6.4 4.3 7.1 8.1 10.6 15.7 5.5 7.8 8.8 4.8 5.7 5.1 5.4 3.6 4.5 2.9 4.5 4.0 3.4 4.4 4.2 3.8 4.3 2.8 4.0 4.6 7.7 3.9 2.7 7.3 8.5 7.8 7.6 6.4 7.5 8.7 7.7 8.0 6.8 8.1 10.8 4.2 9.6 10.3 28.7 8.8 3.6 6.4 15.8 7.4 13.5 11.7 8.4 32.5 20.0 12.5 16.5 12.5 13.6 10.1 13.6 21.5 17.1 8.4 7.9 6.1 6.9 4.2 31.5 10.6 18.2 24.4 5.8 13.3 8.7 6.3 22.4 7.1 23.1 24.6 23.5 12.9 9.5 20.3 10.0 9.6 3.5 7.2 10.2 5.4 17.8 26.9 14.8 7.2 13.0 20.6 17.8 6.2 2.2 13.1 7.1 26.5 26.3 11.9 45.9 0.0 9.0 7.4 5.2 11.5 13.8 6.0 10.1 7.8 9.5 15.9 8.7 PCCB ENSG00000114054 "Propionyl-CoA carboxylase subunit beta" P05166 3 136250340-136337896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 202.1" "Cell type enhanced" "Detected in all" "Early spermatids: 316.7;Late spermatids: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced "Intracellular and membrane" NA NA 120000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA036939: AB_10671366, HPA036940: AB_10669779" "unprognostic (2.74e-1)" "unprognostic (7.88e-3)" "unprognostic (3.99e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.47e-7)" "unprognostic (2.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" 34.4 75.1 23.3 15.2 33.6 37.9 27.5 31.4 29.3 17.5 35.5 43.6 38.1 13.8 13.9 26.3 19.2 17.0 94.6 23.6 28.5 88.9 202.1 14.8 16.2 31.1 29.4 12.1 32.0 57.0 15.6 19.6 30.4 23.7 41.9 17.2 23.6 21.7 83.8 15.1 27.5 22.6 27.1 12.7 26.1 38.8 29.8 21.1 37.9 91.4 20.7 20.5 11.4 47.8 64.8 45.8 42.4 64.4 30.2 34.5 75.4 33.0 35.5 49.1 69.6 67.9 44.7 80.3 89.4 46.6 44.0 35.1 50.3 44.0 69.4 47.8 43.0 140.8 49.5 101.4 66.4 107.3 60.2 40.8 41.4 31.0 69.4 30.5 56.1 131.6 104.5 41.0 38.0 123.1 109.3 63.1 36.0 96.8 40.9 29.3 34.6 116.6 89.9 69.4 84.0 62.9 84.4 48.9 77.5 35.2 98.3 62.9 42.0 24.5 26.0 69.2 29.6 78.3 70.0 66.9 34.9 41.7 29.9 7.3 29.5 7.5 22.6 30.8 25.4 21.7 14.7 23.2 44.6 19.8 15.1 18.7 2.7 25.9 28.7 38.5 14.8 22.6 23.3 33.6 31.4 29.3 23.6 28.5 31.1 29.4 30.4 27.1 29.8 47.8 5.6 9.6 14.0 16.0 9.2 4.1 9.4 37.9 3.4 16.0 12.5 5.3 51.1 8.6 28.4 20.2 10.4 57.1 8.0 15.1 39.2 24.6 316.7 14.1 9.5 8.1 9.1 53.2 16.5 14.0 27.1 13.6 14.8 14.1 29.2 18.1 9.3 76.3 35.1 11.8 22.7 15.1 24.4 11.7 5.2 159.0 13.7 11.4 19.6 16.9 16.5 11.8 10.3 22.1 50.9 14.4 16.7 10.9 22.6 10.4 19.2 97.3 23.6 13.2 13.1 13.6 13.1 11.3 29.0 16.2 3.3 50.9 9.9 52.8 25.1 12.2 PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512979 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 31.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 3.3" "Cancer enriched" "Detected in single" 10 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 9.1;SCLC-21H: 7.3;SH-SY5Y: 14.2;SuSa: 10.0" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.05e-2)" "unprognostic (1.26e-3)" "unprognostic (4.78e-2)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (7.84e-2)" "unprognostic (9.48e-2)" "unprognostic (3.27e-1)" "unprognostic (4.55e-1)" "unprognostic (1.17e-1)" "unprognostic (8.72e-3)" "unprognostic (4.73e-3)" "unprognostic (2.20e-4)" "unprognostic (8.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.75e-2)" 0.2 1.1 17.3 0.1 12.2 0.0 0.2 19.3 14.6 0.3 0.1 0.6 0.0 0.4 0.2 0.2 0.3 0.2 2.2 12.7 13.9 0.1 0.1 0.4 0.1 12.9 21.9 0.3 0.3 0.0 1.1 0.1 10.3 0.2 0.1 6.6 0.3 0.1 0.7 0.5 0.1 0.2 22.4 0.1 0.2 0.9 14.3 0.0 0.1 0.3 0.2 0.2 0.3 31.4 0.0 0.0 0.9 0.2 0.2 0.7 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.8 0.9 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 1.3 0.0 0.0 9.1 0.5 0.0 0.0 0.1 7.3 14.2 0.1 0.0 0.1 10.0 0.1 0.3 0.1 0.8 0.1 0.2 0.6 0.2 0.0 0.2 0.6 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 12.2 19.3 14.6 12.7 13.9 12.9 21.9 10.3 22.4 14.3 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCP4 PEP-19 ENSG00000183036 "Purkinje cell protein 4" P48539 21 39867438-39929397 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 647.3;seminal vesicle: 1280.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 600.9;Distal tubular cells: 645.6;Horizontal cells: 1398.2;Proximal tubular cells: 941.2" "Cancer enhanced" "Detected in many" "prostate cancer: 41.7;thyroid cancer: 48.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 215.9;T-47d: 64.7" "Low region specificity" "Detected in all" HPA005792 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli fibrillar center" "HPA005792: AB_1855086" "unprognostic (6.82e-2)" "prognostic favorable (9.76e-4)" "unprognostic (5.26e-2)" "unprognostic (1.56e-1)" "unprognostic (4.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (3.95e-3)" "unprognostic (2.63e-1)" "prognostic favorable (1.85e-7)" "unprognostic (9.00e-2)" "unprognostic (2.99e-3)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" 5.2 52.9 197.6 2.0 647.3 0.0 8.4 166.2 202.0 180.9 509.6 135.5 5.1 126.9 365.6 228.2 10.2 4.2 4.6 121.8 175.9 52.1 0.5 0.6 0.2 75.6 299.1 3.5 6.2 19.7 8.8 2.0 70.2 323.4 32.4 385.3 21.3 1280.1 0.6 14.8 6.0 54.6 64.1 2.6 7.1 0.9 491.1 7.9 227.7 0.0 1.0 468.0 128.6 85.5 0.0 0.0 3.1 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 2.3 1.9 0.0 0.0 0.0 0.0 215.9 0.5 0.0 0.3 0.3 0.0 34.8 0.0 0.2 64.7 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.6 647.3 166.2 202.0 121.8 175.9 75.6 299.1 70.2 64.1 491.1 85.5 0.0 0.0 1.5 15.3 2.9 3.1 0.4 0.0 0.0 600.9 0.4 0.4 8.8 2.8 0.0 77.3 62.6 0.3 0.0 0.1 645.6 0.4 1.3 0.0 0.2 5.0 1.2 0.0 71.3 0.2 0.3 1.5 0.0 0.0 0.0 0.4 0.0 0.1 0.2 1398.2 21.5 0.2 0.0 0.0 7.5 0.4 9.6 7.0 21.4 8.4 0.0 68.4 0.0 7.5 11.9 0.8 0.2 0.4 0.0 4.4 0.0 941.2 0.0 200.0 0.0 0.0 77.4 3.4 9.5 0.0 6.0 2.9 2.2 0.5 0.5 1.0 PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900958-81911432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.7;testis: 261.7" "Group enriched" "Detected in many" 7 "Early spermatids: 763.2;Late spermatids: 2829.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 218.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Approved Nucleoplasm,Cytosol NA NA 84000 "Cluster 26: Non-specific - Mitochondria" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA023033: AB_1855094, HPA023034: AB_1855095" "unprognostic (4.05e-3)" "unprognostic (4.39e-3)" "unprognostic (3.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (9.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-1)" "unprognostic (4.24e-1)" "unprognostic (8.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "prognostic favorable (4.29e-6)" "unprognostic (1.19e-1)" "unprognostic (8.59e-2)" "unprognostic (1.63e-1)" "unprognostic (4.47e-2)" 29.7 16.8 40.0 9.5 40.1 12.1 25.2 44.4 45.8 14.9 30.4 25.5 63.9 18.0 13.5 26.3 23.9 9.9 47.7 41.2 37.7 44.0 165.7 21.3 12.0 47.0 43.0 20.9 25.3 20.2 14.4 12.0 47.3 24.2 16.7 8.6 22.3 12.1 33.5 16.3 43.0 9.6 41.3 12.8 35.4 261.7 41.0 13.5 16.2 29.3 11.9 21.2 15.1 44.0 42.6 23.9 18.8 53.1 91.8 48.0 27.9 29.9 63.2 40.7 48.0 94.0 43.0 14.8 16.0 31.1 75.3 34.5 28.6 55.1 23.5 4.5 24.3 32.1 33.3 218.2 97.8 32.5 26.0 39.8 31.4 36.8 28.4 14.5 38.6 44.0 60.6 29.6 30.8 35.7 39.3 40.1 15.1 147.2 25.9 25.4 20.2 52.4 49.2 78.8 23.9 21.9 22.4 121.7 29.0 36.5 33.9 75.3 26.1 30.0 19.7 22.9 25.0 19.3 9.1 15.3 31.2 42.8 29.9 1.5 2.4 0.9 4.6 2.6 3.0 4.2 5.5 4.7 4.5 5.6 4.5 4.6 0.7 3.3 2.1 4.4 3.6 3.1 40.0 40.1 44.4 45.8 41.2 37.7 47.0 43.0 47.3 41.3 41.0 44.0 11.5 0.0 17.3 15.0 11.1 5.4 8.1 11.7 6.8 12.5 25.1 11.0 17.0 62.9 9.6 25.8 0.0 73.1 21.0 41.6 119.3 19.5 763.2 29.0 7.5 8.7 13.9 47.8 5.3 18.3 39.7 7.7 36.2 15.8 9.5 39.6 21.8 166.0 24.1 16.8 4.6 29.1 20.3 11.8 3.3 2829.0 27.7 8.1 33.8 0.0 14.7 26.7 22.6 3.5 12.2 17.8 18.8 25.9 13.4 11.4 144.4 130.3 29.4 10.6 26.3 6.2 11.5 253.1 18.1 16.5 5.7 50.8 13.6 34.4 48.7 7.7 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 68.9;heart muscle: 58.5" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1071.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.4;fHDF/TERT166: 148.3;hTERT-RPE1: 44.9;U-251 MG: 77.9;WM-115: 105.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.4 1.8 19.2 2.5 43.0 0.0 4.3 21.4 39.9 0.7 0.0 3.0 1.4 2.4 6.0 6.4 10.5 1.5 58.5 18.9 24.2 4.2 0.1 4.9 0.6 29.4 27.9 3.8 2.6 0.3 1.3 3.2 27.7 2.0 1.8 7.4 1.8 3.2 0.6 0.4 3.3 5.0 16.4 0.6 4.0 3.8 28.6 1.6 3.1 4.0 0.1 9.8 1.4 68.9 0.3 5.8 15.5 0.0 0.6 0.4 0.2 44.4 18.3 20.8 17.1 0.0 0.0 0.0 0.2 148.3 0.0 1.2 0.0 0.0 27.1 0.0 0.0 1.3 1.4 0.0 0.1 0.0 31.9 1.9 0.0 4.3 0.2 44.9 7.1 0.0 0.1 0.1 1.7 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 0.0 22.5 0.0 6.8 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.2 22.8 8.6 0.4 77.9 0.4 0.0 0.0 2.4 0.5 105.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 43.0 21.4 39.9 18.9 24.2 29.4 27.9 27.7 16.4 28.6 68.9 1.2 0.0 0.0 7.5 0.1 0.0 0.7 0.1 1.2 69.5 2.8 17.1 136.0 0.0 0.7 1.8 52.1 0.0 0.1 0.0 0.0 4.8 53.4 0.2 0.1 3.9 0.0 0.0 70.8 0.4 0.0 8.7 0.0 0.4 8.8 0.2 0.0 0.0 0.1 3.3 169.2 0.0 59.0 0.0 0.2 50.3 0.3 0.5 0.0 15.9 0.0 0.9 0.0 196.6 1071.4 0.2 0.0 0.4 0.1 0.2 0.0 0.0 2.2 4.7 0.0 0.9 9.4 1.3 1.2 0.2 0.0 0.0 0.1 1.2 0.0 0.0 PDE4DIP "CMYA2, KIAA0454, KIAA0477, MMGL" ENSG00000178104 "Phosphodiesterase 4D interacting protein" Q5VU43 1 148808181-149048286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 729.5;skeletal muscle: 2164.0;tongue: 1379.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 702.6;Rod photoreceptor cells: 272.3;Syncytiotrophoblasts: 309.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 289.6;ASC TERT1: 233.8;K-562: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012678 Supported "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA012678: AB_1855123" "unprognostic (2.14e-1)" "unprognostic (3.27e-1)" "unprognostic (5.31e-2)" "unprognostic (6.73e-2)" "unprognostic (7.82e-2)" "unprognostic (1.16e-2)" "unprognostic (2.17e-1)" "unprognostic (9.72e-2)" "unprognostic (7.65e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-2)" "unprognostic (5.08e-2)" "unprognostic (1.70e-3)" "unprognostic (1.82e-1)" "unprognostic (4.14e-2)" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" 32.9 16.9 103.0 20.9 82.9 15.8 22.3 142.7 106.1 28.0 32.4 22.5 24.2 17.4 73.5 37.9 19.8 19.5 729.5 115.5 118.5 42.0 63.5 36.1 21.7 102.2 95.6 8.6 21.4 84.6 53.1 68.5 109.7 29.2 25.4 173.3 34.9 22.9 2164.0 26.1 29.4 18.8 96.8 17.2 29.7 9.2 139.9 12.1 16.9 1379.7 23.2 24.0 17.1 114.9 39.2 7.5 10.6 11.6 289.6 233.8 60.7 45.2 42.3 42.7 55.7 35.5 24.1 19.8 13.7 64.5 121.3 19.8 25.7 31.5 72.1 14.7 36.8 10.0 16.2 14.2 76.2 8.8 10.2 167.5 61.9 181.7 97.8 96.9 17.1 16.3 222.1 45.0 76.8 66.2 6.9 5.4 37.1 32.3 15.9 14.6 26.5 7.7 25.4 39.9 50.1 4.7 44.1 123.4 36.1 44.7 37.5 11.7 22.9 49.3 11.2 124.7 100.9 19.9 29.6 29.1 200.6 8.0 30.2 10.6 5.7 4.5 5.3 6.1 5.5 12.0 10.6 7.1 7.0 11.0 8.1 4.5 1.3 4.9 2.1 3.0 14.4 4.8 103.0 82.9 142.7 106.1 115.5 118.5 102.2 95.6 109.7 96.8 139.9 114.9 5.7 51.3 45.1 81.3 24.0 28.8 9.9 19.8 23.3 71.0 16.1 11.3 702.6 24.3 45.4 69.9 114.7 184.6 9.5 24.0 62.6 13.1 38.9 41.1 14.2 15.7 43.2 7.4 85.8 7.1 148.3 54.2 20.4 27.0 13.9 6.1 5.3 80.8 45.0 33.7 81.1 32.0 20.3 46.1 90.4 50.0 10.5 68.7 55.2 6.5 21.5 45.7 14.4 65.9 41.5 4.5 25.1 9.8 37.5 4.1 48.8 20.7 88.0 272.3 32.9 131.2 40.1 8.7 15.9 14.6 16.3 309.2 24.0 4.2 24.2 4.3 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 508.8;tongue: 770.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 479.9;Distal tubular cells: 354.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favorable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 93.0 69.0 62.1 37.9 66.9 88.1 63.1 66.2 91.5 55.9 84.4 112.6 87.0 53.1 78.9 76.8 49.1 29.3 508.8 68.2 67.0 174.1 118.3 47.2 36.6 64.5 62.7 50.6 83.4 161.0 48.7 43.1 65.0 48.4 104.4 90.1 109.7 63.4 459.0 60.9 82.1 51.8 59.6 49.3 121.8 24.0 67.4 52.3 64.5 770.2 59.1 61.7 56.1 71.1 124.9 151.4 107.9 114.2 102.3 77.7 131.6 83.8 74.6 170.2 130.7 216.6 78.2 212.2 60.6 102.0 226.7 159.0 334.2 145.8 178.1 70.1 186.1 104.8 264.0 194.2 107.8 170.3 82.8 100.9 132.8 157.3 154.4 85.6 105.3 129.8 94.2 87.2 120.7 164.5 142.7 173.5 110.0 227.4 261.7 145.2 180.9 260.3 298.0 125.1 59.7 62.6 134.1 167.8 158.1 229.8 177.1 118.1 65.4 87.6 78.6 240.9 108.6 73.3 82.0 140.5 82.4 117.2 77.4 99.9 87.4 65.3 72.3 119.9 88.9 103.4 69.4 79.5 115.7 82.1 67.7 72.0 15.5 98.1 109.1 76.9 84.4 89.6 62.1 66.9 66.2 91.5 68.2 67.0 64.5 62.7 65.0 59.6 67.4 71.1 34.1 44.8 44.4 18.6 30.7 29.8 59.7 135.4 25.0 59.0 37.0 29.3 479.9 87.2 74.8 152.6 33.3 105.0 32.5 73.0 354.1 88.8 2.5 41.2 33.7 36.8 41.9 55.8 21.2 59.8 120.7 49.2 49.5 36.9 42.6 39.7 18.2 76.3 73.2 25.2 24.6 64.4 71.2 26.8 30.5 4.1 35.4 32.5 56.9 9.4 40.8 49.0 26.8 13.0 11.5 47.4 52.5 40.6 43.3 47.1 88.6 213.7 33.1 69.1 32.9 37.5 51.7 51.1 25.3 45.2 33.4 133.4 31.6 25.4 130.3 55.8 PDHB PDHE1B ENSG00000168291 "Pyruvate dehydrogenase E1 subunit beta" P11177 3 58427630-58433857 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 299.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 300.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033794, HPA036744, HPA036745" Enhanced Supported Nucleoplasm,Mitochondria No No 61000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "CAB033794: AB_2162946, HPA036744: AB_10670921, HPA036745: AB_2675285" "unprognostic (2.06e-2)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (7.22e-2)" "unprognostic (1.42e-1)" "unprognostic (3.20e-2)" "unprognostic (6.13e-2)" "unprognostic (9.62e-2)" "unprognostic (5.94e-2)" "unprognostic (3.98e-1)" "unprognostic (2.35e-1)" "prognostic favorable (2.79e-8)" "unprognostic (2.67e-1)" "unprognostic (8.37e-2)" "unprognostic (1.06e-2)" "unprognostic (9.85e-2)" 59.9 76.5 48.7 42.2 50.2 25.7 42.9 53.9 62.7 43.3 63.6 56.8 42.5 38.5 44.6 57.4 37.7 35.9 175.0 49.7 52.3 100.8 110.7 36.4 53.1 51.7 49.4 26.5 36.4 88.8 44.1 57.0 51.5 48.5 60.4 30.7 45.9 52.1 272.6 36.8 37.6 63.8 51.6 42.8 53.9 42.3 53.1 53.1 40.8 299.4 56.0 49.7 35.9 54.3 66.5 90.9 92.3 69.8 91.7 111.1 110.4 81.6 101.3 117.9 120.6 165.1 62.6 140.3 44.9 103.8 109.0 37.6 113.2 74.9 90.0 81.7 83.0 125.4 163.7 126.0 92.5 103.0 67.9 97.9 67.7 95.5 55.8 137.5 103.1 114.2 65.9 61.5 129.5 63.1 98.2 107.8 127.2 69.2 101.3 46.3 71.8 136.1 188.1 89.1 63.7 70.2 75.6 107.2 85.4 131.3 159.0 108.7 76.3 62.9 83.7 66.8 94.2 85.2 129.9 99.2 96.2 120.8 60.7 57.8 98.9 98.7 83.2 115.1 87.9 102.2 81.7 80.5 141.1 103.4 90.9 82.4 19.6 129.4 109.7 94.7 113.2 124.1 48.7 50.2 53.9 62.7 49.7 52.3 51.7 49.4 51.5 51.6 53.1 54.3 57.8 60.9 34.5 5.9 45.3 27.9 40.7 142.0 26.7 31.8 29.4 31.6 300.6 48.6 96.0 35.0 25.0 174.1 35.3 41.0 230.9 95.9 76.3 37.0 37.3 58.0 58.0 22.5 10.9 72.2 101.6 54.1 29.6 34.2 39.3 48.5 46.1 76.1 84.6 57.2 13.3 50.4 162.8 37.9 26.6 16.9 60.3 37.2 56.9 9.4 76.5 61.7 70.0 9.0 13.6 55.9 43.0 51.1 38.8 19.1 45.8 146.8 70.7 45.9 65.7 30.8 72.3 98.2 88.3 42.8 29.8 157.2 44.7 224.4 53.0 37.7 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 216.2;tongue: 285.0" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 123.0;Proximal tubular cells: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favorable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 40.8 63.8 49.9 8.7 51.2 5.0 26.4 65.7 58.2 30.5 37.1 42.7 28.1 29.4 124.4 21.8 24.3 18.0 116.6 50.6 41.8 62.7 50.8 15.3 10.1 40.8 44.0 48.2 44.3 40.7 17.0 14.7 41.8 23.5 21.5 14.7 25.7 27.4 216.2 26.0 32.5 25.7 40.8 18.4 33.7 13.7 44.6 12.6 27.3 285.0 9.2 30.9 22.2 44.6 12.4 17.5 20.6 18.5 21.2 16.5 2.2 13.2 19.3 19.3 18.5 1.7 13.2 15.5 21.7 37.0 13.0 6.4 13.7 5.3 18.8 30.6 19.3 14.0 17.1 13.2 11.3 0.0 15.0 33.6 19.6 12.5 0.9 33.7 17.2 20.0 5.7 15.0 11.0 15.8 11.8 0.0 4.5 37.2 17.1 17.5 45.8 21.1 10.4 10.4 13.8 20.7 18.7 5.9 9.0 25.0 35.0 13.7 8.8 22.5 18.4 16.0 10.1 29.4 29.9 8.2 33.3 4.9 15.4 14.3 16.2 8.9 16.2 12.9 12.8 12.9 14.8 18.0 18.4 13.8 17.2 18.0 2.6 22.9 14.1 25.8 22.4 17.4 49.9 51.2 65.7 58.2 50.6 41.8 40.8 44.0 41.8 40.8 44.6 44.6 17.9 9.6 10.3 18.3 12.1 15.2 12.3 12.4 17.6 19.0 16.0 26.8 5.4 12.8 11.7 20.2 6.2 19.6 16.7 38.6 58.7 11.7 8.8 6.5 12.1 11.8 13.8 10.8 18.6 9.1 3.6 17.7 13.7 7.8 1.3 19.0 18.2 52.0 19.9 43.7 15.6 50.2 16.2 13.6 9.1 18.9 24.2 12.0 24.9 8.4 14.5 37.3 7.2 6.0 11.3 6.2 55.2 52.6 25.9 6.7 123.0 131.9 6.5 11.0 19.7 15.0 20.5 3.3 11.7 14.6 18.8 7.9 12.9 29.0 36.9 11.3 PDZRN3 "KIAA1095, LNX3, SEMACAP3, SEMCAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382431-73624941 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 256.0;Excitatory neurons: 183.1;Inhibitory neurons: 258.3;Microglial cells: 329.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "AF22: 32.1;ASC diff: 57.0;ASC TERT1: 29.6;BJ hTERT+: 42.0;HSkMC: 41.4;U-87 MG: 30.4" "Group enriched" "Detected in many" 4 "amygdala: 15.1;basal ganglia: 8.1;cerebral cortex: 19.5;hippocampal formation: 16.1;white matter: 7.2" "Low region specificity" "Detected in many" "HPA038822, HPA061420" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA038822: AB_10675952, HPA061420: AB_2684512" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.35e-5)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (8.47e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "prognostic favorable (4.93e-4)" "unprognostic (8.38e-2)" "prognostic favorable (3.65e-7)" "unprognostic (8.63e-3)" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (2.86e-3)" 29.9 35.7 14.9 10.2 16.3 0.0 24.0 8.5 20.9 45.2 58.0 84.0 9.2 64.1 24.5 27.8 26.7 27.4 48.0 16.7 10.6 10.7 2.1 14.9 4.5 13.0 11.8 69.4 6.9 0.8 4.6 17.5 11.0 31.7 13.9 6.3 20.9 29.0 91.8 17.3 24.4 38.4 13.1 2.4 38.7 6.4 17.1 2.9 3.6 22.4 1.4 46.7 32.0 13.2 0.0 0.0 32.1 0.1 57.0 29.6 0.1 16.9 42.0 5.0 3.2 16.2 0.0 0.1 0.1 22.8 0.8 0.0 0.0 0.0 4.8 0.0 2.2 0.0 0.0 0.0 9.5 0.0 0.1 41.4 0.0 13.8 0.1 6.0 0.0 0.0 0.0 0.0 4.9 2.1 0.0 0.2 4.6 0.0 0.2 0.0 8.4 0.1 0.0 0.0 3.7 10.5 0.0 7.8 12.7 9.2 4.5 0.0 0.0 20.6 1.5 23.6 2.2 0.7 0.0 0.2 30.4 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 14.9 16.3 8.5 20.9 16.7 10.6 13.0 11.8 11.0 13.1 17.1 13.2 5.9 0.0 0.0 256.0 0.5 2.4 9.7 0.0 1.8 19.3 7.5 7.6 65.0 0.0 0.0 5.5 6.2 0.5 2.7 1.0 1.9 0.0 0.4 2.1 45.2 2.3 21.1 0.0 183.1 0.4 0.5 25.2 2.0 3.3 0.0 35.0 0.0 0.0 0.8 0.0 258.3 9.1 0.0 0.0 2.9 1.3 23.3 0.7 16.0 329.8 0.0 22.5 0.0 21.6 5.5 0.3 0.9 28.2 0.1 10.9 0.1 7.1 0.0 1.9 0.0 4.6 19.6 0.5 6.2 2.9 1.8 0.8 0.5 12.4 3.9 6.3 PEBP1 "HCNP, PBP, PEBP, RKIP" ENSG00000089220 "Phosphatidylethanolamine binding protein 1" P30086 12 118136124-118145584 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2083.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 3705.6;Hepatocytes: 2242.4;Proximal enterocytes: 2177.7;Proximal tubular cells: 4542.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA008819, CAB009906, CAB013493, HPA063904" Enhanced Approved "Plasma membrane,Cytosol" NA NA 51000000 "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB009906: AB_2163173, CAB013493: AB_2533305, HPA008819: AB_1855173, HPA063904: AB_2732708" "unprognostic (4.57e-1)" "unprognostic (1.03e-3)" "unprognostic (3.28e-2)" "unprognostic (3.39e-3)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-2)" "unprognostic (7.35e-3)" "unprognostic (5.67e-2)" "unprognostic (3.55e-2)" "prognostic favorable (1.52e-4)" "unprognostic (1.63e-1)" "prognostic favorable (2.15e-13)" "unprognostic (2.17e-1)" "unprognostic (7.72e-2)" "unprognostic (7.96e-2)" "unprognostic (8.80e-2)" 217.9 1754.1 941.2 84.0 966.0 121.8 235.5 987.9 1049.0 258.0 958.4 208.9 601.4 186.6 383.7 219.5 218.4 154.8 463.8 932.6 951.5 1046.1 2083.1 176.4 122.7 959.0 965.9 335.9 357.5 1162.7 292.3 128.8 982.6 261.6 191.2 336.1 344.5 233.2 580.3 190.3 510.6 167.6 1006.6 121.2 201.7 152.2 1025.0 138.1 739.7 546.8 160.2 200.8 179.0 1081.7 289.2 241.6 340.0 348.8 493.5 250.2 500.0 214.5 262.3 347.7 177.1 151.6 96.4 439.6 221.3 336.2 139.9 194.4 495.0 202.8 257.7 115.1 454.2 220.0 274.7 1021.7 289.2 403.6 94.5 240.8 334.7 203.9 140.0 396.1 162.7 240.9 375.8 169.2 356.4 346.3 226.8 813.7 319.7 243.1 273.9 446.1 235.6 829.7 428.7 277.2 397.5 306.9 439.9 306.2 446.0 200.4 443.6 293.0 168.9 253.7 147.0 254.0 237.3 161.6 315.1 234.1 301.1 303.2 280.9 5.0 67.5 20.0 155.2 76.4 247.0 271.7 258.9 193.1 205.1 210.0 244.6 201.2 8.0 138.1 68.6 231.6 259.7 258.4 941.2 966.0 987.9 1049.0 932.6 951.5 959.0 965.9 982.6 1006.6 1025.0 1081.7 193.7 403.8 433.3 101.5 230.9 318.1 449.3 367.6 288.5 539.4 538.4 590.7 697.3 713.4 243.2 783.5 95.9 999.6 144.6 207.1 3705.6 507.9 44.3 499.3 319.0 186.5 320.6 218.1 93.7 244.6 862.3 347.9 169.2 369.8 371.8 419.7 213.8 2242.4 591.6 721.8 99.6 378.8 335.7 201.4 239.0 84.4 543.1 195.3 743.5 53.4 296.8 1792.2 101.0 39.2 199.8 184.2 313.3 731.6 279.3 517.4 2177.7 4542.6 291.6 411.6 368.1 337.5 347.8 330.6 145.7 367.7 325.2 615.5 216.7 921.6 631.3 399.5 PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 382.5;skeletal muscle: 670.8;tongue: 581.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 109.0;Alveolar cells type 2: 177.3;Cardiomyocytes: 144.7;Muller glia cells: 198.7" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-266/70: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" NA NA 190000000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" 1.1 3.4 12.3 0.3 16.7 0.0 3.3 21.2 9.2 0.6 19.2 0.6 0.0 0.5 382.5 6.8 2.2 1.1 200.7 8.5 15.8 2.6 0.9 115.1 0.7 15.6 20.3 1.7 34.5 82.6 13.2 0.3 20.2 45.8 0.2 12.9 21.1 2.8 670.8 1.4 0.6 0.4 8.7 0.8 9.2 6.6 28.7 1.2 56.7 581.4 1.6 0.3 0.5 15.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 12.3 16.7 21.2 9.2 8.5 15.8 15.6 20.3 20.2 8.7 28.7 15.5 1.5 109.0 177.3 15.3 2.2 1.9 1.0 0.1 0.0 10.2 5.7 4.7 144.7 0.0 7.4 1.8 2.1 0.8 1.4 0.3 3.9 0.0 34.8 1.7 2.0 2.4 0.0 0.0 10.0 9.3 0.2 10.1 2.0 7.0 7.6 0.4 3.9 0.7 1.2 10.1 9.6 0.3 2.0 0.0 0.8 28.4 3.4 1.4 1.8 6.5 0.1 198.7 5.2 6.6 0.9 0.3 0.1 10.9 1.5 23.8 0.5 5.9 2.9 8.6 0.0 25.2 2.1 14.8 1.2 0.0 0.9 0.0 1.6 1.1 0.3 1.0 PET100 C19orf79 ENSG00000229833 "PET100 cytochrome c oxidase chaperone" P0DJ07 19 7629793-7631956 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067288 Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA067288: AB_2732762" "unprognostic (7.02e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.57e-1)" "unprognostic (9.87e-3)" "unprognostic (2.14e-1)" "unprognostic (4.18e-2)" "unprognostic (1.70e-1)" "prognostic favorable (7.97e-4)" "unprognostic (4.89e-1)" "unprognostic (2.88e-3)" "unprognostic (2.49e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (2.66e-2)" "prognostic favorable (2.44e-4)" 35.0 45.6 77.8 38.3 76.8 85.2 38.8 77.3 125.7 28.0 81.7 39.5 38.1 25.1 46.1 40.3 23.4 6.6 70.0 77.0 77.2 49.7 65.5 28.4 26.6 76.8 78.1 23.0 33.1 75.9 41.5 23.0 77.3 29.9 28.1 64.8 43.3 22.8 79.3 31.3 33.0 17.0 75.5 36.5 45.8 31.1 76.7 75.9 34.7 65.1 31.9 27.3 29.5 79.0 72.2 63.5 112.2 67.9 54.9 39.3 40.7 60.0 34.6 40.9 39.7 60.6 47.3 48.3 102.8 46.3 49.8 61.9 52.3 55.4 34.1 110.5 108.0 69.1 136.8 96.5 27.4 118.8 62.2 44.4 35.4 27.6 28.6 64.5 59.2 113.5 50.5 179.4 43.2 80.7 128.1 182.0 73.0 83.2 141.0 77.0 64.4 113.6 85.8 86.8 63.3 74.3 79.4 71.5 68.3 69.6 51.9 153.2 63.6 31.8 39.1 64.4 90.1 157.5 134.0 86.0 58.1 89.3 38.7 806.4 481.1 576.6 241.3 408.1 227.5 338.5 276.8 256.6 309.2 332.5 256.1 268.1 468.2 227.4 370.5 538.5 390.0 501.2 77.8 76.8 77.3 125.7 77.0 77.2 76.8 78.1 77.3 75.5 76.7 79.0 109.5 150.6 189.0 6.2 137.2 50.2 39.8 194.1 87.6 52.7 136.8 109.6 54.1 197.3 150.6 259.3 22.9 126.7 159.3 275.4 215.2 215.7 51.1 156.7 101.9 93.3 191.5 238.4 4.5 318.3 128.9 82.6 144.3 160.7 106.9 69.0 171.0 542.3 171.7 18.5 4.5 255.4 158.7 236.4 103.8 47.3 101.5 161.2 113.8 10.3 228.8 123.0 130.7 4.5 8.4 351.4 302.4 83.1 198.9 57.0 341.9 295.9 160.2 96.5 85.5 52.0 80.4 126.5 84.0 127.0 59.1 178.8 131.0 30.1 213.1 53.0 PEX7 "PTS2R, RD" ENSG00000112357 "Peroxisomal biogenesis factor 7" O00628 6 136822564-136913934 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049202 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Vesicles" "HPA049202: AB_2680674" "unprognostic (1.36e-2)" "unprognostic (2.07e-2)" "prognostic favorable (1.61e-4)" "unprognostic (4.01e-3)" "unprognostic (2.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (6.88e-2)" "prognostic favorable (1.85e-10)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (2.52e-2)" "unprognostic (2.65e-1)" 5.2 14.8 4.6 2.0 4.8 3.8 11.9 6.0 5.2 6.8 5.1 7.9 5.3 4.2 17.2 7.3 8.7 4.5 11.7 4.2 4.2 15.6 9.1 4.9 3.2 4.3 4.4 5.0 26.9 17.1 6.0 4.1 4.5 10.4 8.4 6.9 10.6 6.4 10.7 11.2 4.7 3.3 4.4 3.3 15.6 10.0 4.7 3.7 11.0 9.8 3.3 5.4 6.7 5.5 4.4 4.3 4.4 6.2 6.6 9.8 2.4 6.1 8.9 7.5 7.4 4.9 6.0 1.5 11.3 8.3 8.5 5.3 3.3 13.8 9.8 5.7 7.5 6.4 4.3 0.9 13.9 8.1 5.3 9.6 13.1 5.4 7.9 8.7 5.4 12.0 13.0 5.2 10.6 13.4 3.5 7.9 5.0 13.9 8.3 4.8 3.4 5.7 17.4 6.4 8.3 10.6 6.5 9.0 8.4 4.9 5.8 7.7 2.5 4.8 1.7 7.3 5.3 6.9 5.1 0.0 4.2 6.4 4.9 2.9 1.3 2.2 0.7 1.0 0.7 1.5 1.3 1.6 2.3 1.0 2.4 1.5 0.9 1.6 1.9 1.8 2.3 0.9 4.6 4.8 6.0 5.2 4.2 4.2 4.3 4.4 4.5 4.4 4.7 5.5 4.9 3.2 9.4 10.7 6.3 12.1 14.9 16.5 9.1 9.1 19.5 13.8 18.7 11.5 14.7 11.0 8.4 19.6 2.3 11.6 60.7 16.5 12.5 18.7 6.4 5.6 10.3 15.8 12.4 22.7 21.0 6.8 10.2 11.1 14.0 7.9 6.1 7.0 12.4 0.0 14.7 21.8 30.5 5.7 6.2 10.2 9.0 6.4 14.2 5.6 11.9 20.8 4.1 17.6 19.9 16.7 13.2 9.8 3.7 16.0 15.0 38.3 16.1 9.9 6.6 5.7 8.2 30.6 16.7 15.4 18.2 17.1 6.6 24.3 17.2 17.4 PFKFB2 ENSG00000123836 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2" O60825 1 207034366-207081024 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 83.3" "Cell type enhanced" "Detected in many" "Astrocytes: 105.1;Cardiomyocytes: 79.0;Late spermatids: 158.2;Rod photoreceptor cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 20.8;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 8 "dendritic cells: 23.8;granulocytes: 20.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049975, HPA063575" Uncertain Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA049975: AB_2680977, HPA063575: AB_2685046" "unprognostic (1.30e-1)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-2)" "unprognostic (2.27e-1)" "unprognostic (3.76e-2)" "unprognostic (9.96e-3)" "unprognostic (9.74e-2)" "unprognostic (7.27e-2)" "unprognostic (2.27e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "prognostic favorable (3.23e-7)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (1.86e-2)" 4.3 6.8 13.2 8.3 14.5 23.5 6.4 8.6 15.2 9.1 42.5 22.2 32.2 5.0 11.6 9.6 5.7 5.8 36.0 13.9 11.4 29.7 4.0 13.3 7.0 13.3 13.8 5.2 16.0 15.3 23.1 3.9 12.2 4.8 24.1 83.3 7.6 4.1 49.5 8.1 22.2 5.0 9.7 15.0 15.5 7.0 19.3 20.2 51.7 42.7 6.7 4.2 4.2 18.4 15.0 6.5 4.2 7.3 8.4 4.1 6.9 2.1 2.5 3.6 2.0 16.0 21.1 2.7 3.3 3.3 10.8 20.8 3.1 7.9 2.1 0.6 3.2 21.1 17.4 5.9 7.0 0.0 14.2 5.9 11.7 3.5 19.1 4.3 0.8 8.7 14.6 0.1 2.0 4.5 3.6 0.6 5.8 7.2 9.7 0.0 0.0 0.4 4.9 15.3 6.6 4.0 13.7 22.8 17.4 4.5 15.6 1.8 0.4 0.0 7.6 11.0 1.9 6.6 7.0 1.4 8.8 0.0 3.9 1.6 1.2 20.8 0.3 2.6 0.4 1.9 0.2 0.4 1.1 2.3 0.5 0.6 3.5 1.6 1.9 23.8 0.0 0.7 13.2 14.5 8.6 15.2 13.9 11.4 13.3 13.8 12.2 9.7 19.3 18.4 1.0 6.4 54.8 105.1 5.0 15.2 3.8 5.0 10.2 7.0 3.7 4.2 79.0 4.3 8.7 16.5 0.0 0.7 24.6 53.8 25.4 5.0 51.0 18.0 3.7 4.2 6.0 0.8 14.5 7.6 0.4 4.6 14.8 21.3 9.5 2.3 2.5 5.8 5.6 3.3 13.0 20.1 8.2 13.6 4.9 158.2 2.8 8.5 21.4 11.2 5.4 9.8 5.2 4.5 10.6 16.6 26.2 3.0 3.8 13.5 45.4 32.8 15.3 110.5 0.0 3.3 3.1 5.1 3.2 9.9 11.6 1.5 1.6 7.5 36.9 11.5 PGP ENSG00000184207 "Phosphoglycolate phosphatase" A6NDG6 16 2211593-2214840 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 52.2" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 404.5;Early spermatids: 480.5;Late spermatids: 1591.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043096, HPA046739" Approved Approved "Nuclear bodies" NA NA 250000 "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear bodies" "HPA043096: AB_2678311, HPA046739: AB_2679779" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (2.36e-2)" "unprognostic (7.23e-2)" "unprognostic (2.12e-3)" "unprognostic (1.76e-1)" "unprognostic (5.75e-3)" "unprognostic (5.87e-2)" "unprognostic (7.90e-2)" "unprognostic (4.43e-3)" "unprognostic (6.50e-2)" "unprognostic (9.04e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "prognostic favorable (6.42e-4)" 7.5 11.8 17.3 6.1 17.6 8.3 7.6 19.5 26.9 6.4 10.6 11.2 6.0 8.7 4.7 6.9 7.2 3.2 33.0 16.3 13.3 14.0 11.5 10.0 6.4 26.8 15.2 4.7 7.8 5.6 11.9 5.3 27.6 8.3 3.8 7.8 7.3 4.8 41.1 7.8 11.5 3.4 12.6 13.7 10.3 52.2 15.7 5.5 16.1 18.0 3.8 8.6 5.4 17.8 16.2 26.0 18.9 17.5 7.3 6.1 35.4 18.5 8.6 16.5 17.0 40.3 20.0 12.3 17.7 8.5 13.5 26.7 12.7 15.7 7.4 17.0 35.3 12.4 44.3 18.4 4.9 21.8 19.6 6.8 7.0 15.6 5.7 6.3 10.9 20.0 22.4 12.7 9.3 44.1 25.1 35.7 24.1 9.8 23.9 40.9 16.3 27.5 13.9 10.1 24.1 14.8 16.8 29.8 13.1 13.4 22.9 25.3 10.9 17.6 22.5 15.9 18.7 30.1 13.9 17.8 5.8 19.2 13.7 0.0 0.8 2.5 0.7 1.2 0.1 0.2 0.4 0.5 0.5 0.8 0.2 0.4 0.6 0.1 1.2 0.7 0.5 0.2 17.3 17.6 19.5 26.9 16.3 13.3 26.8 15.2 27.6 12.6 15.7 17.8 35.0 6.4 7.8 17.6 20.9 23.3 7.8 2.6 4.0 196.1 31.1 33.8 40.7 17.2 5.7 40.5 404.5 121.1 44.8 63.6 58.7 10.4 480.5 28.5 22.5 24.7 29.8 38.3 38.0 14.0 107.1 20.3 28.5 27.7 10.2 54.1 20.3 39.2 58.0 144.7 30.9 37.3 2.0 33.1 64.8 1591.0 25.7 37.9 35.6 7.5 20.2 63.4 42.2 11.6 21.9 14.4 32.5 28.2 36.9 21.9 34.8 39.4 3.4 220.6 39.5 19.3 94.3 162.9 64.8 12.7 31.8 54.5 30.0 70.8 50.5 15.2 PHACTR3 "C20orf101, PPP1R123" ENSG00000087495 "Phosphatase and actin regulator 3" Q96KR7 20 59577509-59847711 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 104.4;choroid plexus: 36.5" "Cell type enhanced" "Detected in many" "Astrocytes: 205.7;Excitatory neurons: 100.4;Inhibitory neurons: 88.7;Oligodendrocyte precursor cells: 218.1;Oligodendrocytes: 241.1" "Group enriched" "Detected in some" 5 "glioma: 3.8;lung cancer: 1.6;pancreatic cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 85.4;HBEC3-KT: 64.6;PC-3: 113.2;THP-1: 131.3;U-937: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051834, HPA054847" Enhanced Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA051834: AB_2681629, HPA054847: " "unprognostic (7.14e-2)" "unprognostic (1.22e-1)" "unprognostic (3.72e-2)" "unprognostic (1.43e-7)" "unprognostic (1.99e-1)" "unprognostic (2.87e-2)" "unprognostic (5.83e-3)" "unprognostic (8.92e-2)" "unprognostic (5.02e-2)" "unprognostic (2.30e-2)" "unprognostic (7.71e-2)" "unprognostic (7.22e-2)" "unprognostic (1.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.43e-2)" "unprognostic (2.53e-3)" "unprognostic (1.32e-1)" 0.9 1.2 90.4 0.5 92.4 0.5 0.4 82.0 93.4 0.3 36.5 0.8 0.7 1.0 0.7 1.1 8.6 1.9 4.0 82.3 75.4 2.2 0.6 5.9 0.1 78.5 82.4 6.2 0.2 0.0 1.7 0.6 76.1 0.1 0.8 3.3 0.1 0.0 0.2 1.1 1.0 0.3 74.7 5.5 0.5 0.5 93.7 1.9 0.1 1.0 0.1 0.5 0.1 104.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 85.4 0.0 6.2 1.3 0.0 0.2 0.3 64.6 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 1.4 0.1 10.5 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 17.9 0.3 0.4 113.2 0.0 0.0 0.7 25.1 1.4 2.1 6.5 0.5 0.0 0.1 0.0 0.5 131.3 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 90.4 92.4 82.0 93.4 82.3 75.4 78.5 82.4 76.1 74.7 93.7 104.4 0.3 12.8 0.5 205.7 0.3 0.6 1.3 2.1 0.0 13.8 0.2 0.0 8.9 10.0 8.4 3.7 0.0 0.0 0.0 0.0 1.9 1.1 1.0 7.1 3.7 0.3 1.2 0.0 100.4 0.0 0.0 4.2 0.0 2.1 0.0 0.5 3.3 0.0 0.2 5.0 88.7 0.9 44.7 0.3 1.1 0.9 0.0 3.7 0.0 7.5 0.0 0.8 0.0 218.1 241.1 2.9 0.1 0.0 0.9 2.9 4.3 0.1 1.3 1.9 0.0 2.9 0.9 0.3 1.0 0.1 0.4 0.0 0.1 0.9 4.5 3.2 PHKA2 "PHK, PYK" ENSG00000044446 "Phosphorylase kinase regulatory subunit alpha 2" P46019 X 18892298-18984114 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 42.7;Hepatocytes: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002912 Approved Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA002912: AB_10961321" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.43e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.07e-2)" "unprognostic (3.42e-1)" "unprognostic (1.82e-1)" "prognostic favorable (7.68e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (7.16e-2)" "prognostic favorable (2.96e-5)" 12.7 9.6 4.6 6.8 6.3 15.0 7.6 6.6 5.5 9.0 6.9 6.8 12.5 10.5 6.5 6.3 9.9 8.1 12.6 5.6 5.4 6.7 34.3 6.4 7.7 6.9 5.6 16.8 15.2 8.1 12.8 10.5 6.7 9.7 6.5 10.6 9.5 7.1 7.8 8.8 10.1 6.2 5.5 9.3 8.6 9.7 6.0 12.6 10.1 14.3 7.4 6.2 8.1 7.3 11.3 10.6 6.1 10.2 8.2 7.5 16.6 4.9 4.1 7.1 7.7 11.3 7.3 13.3 3.6 6.4 11.2 10.3 11.0 12.8 7.6 6.5 11.2 15.9 17.6 13.8 5.8 15.2 19.7 12.6 8.3 8.7 12.5 11.8 7.4 13.8 5.3 8.0 5.0 12.0 16.0 25.2 7.5 5.2 11.2 12.4 12.5 14.9 4.6 5.0 5.2 8.0 14.8 15.3 6.8 20.3 18.9 8.8 13.2 9.6 5.3 10.3 7.6 7.6 6.7 10.1 5.4 8.1 5.2 4.3 3.2 7.2 2.0 3.8 2.1 1.6 1.7 1.5 2.1 1.7 1.9 1.9 5.4 3.0 2.5 1.1 2.3 1.9 4.6 6.3 6.6 5.5 5.6 5.4 6.9 5.6 6.7 5.5 6.0 7.3 6.1 9.6 12.9 27.7 5.7 6.5 5.4 6.0 8.6 11.1 8.0 7.4 20.1 12.8 5.1 9.2 10.4 16.8 3.4 9.6 0.0 7.5 7.2 6.4 11.8 7.3 4.2 14.5 15.2 5.1 17.5 5.3 4.1 7.2 1.3 42.7 20.3 57.4 8.0 5.0 19.9 7.4 4.1 18.9 3.8 5.3 7.5 10.5 5.4 13.1 8.3 17.0 7.2 16.6 16.9 6.3 12.6 7.9 7.4 6.9 12.4 4.8 4.1 13.3 0.0 7.4 5.9 7.9 7.9 8.6 4.7 10.5 7.4 12.1 10.7 3.6 PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "skeletal muscle: 264.6;tongue: 172.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 48.6;Hepatocytes: 46.5" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" 4.0 4.1 11.4 0.7 15.0 1.7 2.8 14.8 11.6 1.8 8.8 8.5 1.1 1.3 0.7 5.2 1.9 1.6 18.7 11.8 15.6 1.1 1.6 1.7 0.8 17.6 17.5 1.8 1.2 0.9 2.4 0.3 15.3 2.3 0.7 0.9 5.2 0.5 264.6 3.3 2.5 1.1 16.6 1.5 1.6 1.0 16.9 0.7 2.0 172.3 0.9 4.1 1.2 15.4 1.1 0.8 0.2 0.7 1.1 2.0 0.6 0.1 0.2 0.4 0.3 0.3 0.5 0.3 0.2 0.3 0.5 0.6 0.5 0.1 0.3 0.3 0.9 0.3 1.5 0.3 0.2 0.6 1.2 1.2 0.8 0.5 0.2 0.3 0.0 0.8 0.9 1.5 0.0 0.5 0.9 2.4 0.3 0.3 0.5 0.5 0.0 0.3 0.2 0.8 0.6 0.6 0.1 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.6 1.7 0.5 0.6 0.3 0.9 0.4 0.6 0.4 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.7 0.0 0.1 0.1 0.1 0.0 11.4 15.0 14.8 11.6 11.8 15.6 17.6 17.5 15.3 16.6 16.9 15.4 12.6 12.8 4.2 16.0 10.4 1.3 7.7 0.2 0.6 3.9 25.6 6.7 1.7 48.6 3.7 27.6 0.0 7.5 17.7 9.0 1.9 14.6 2.7 20.8 11.3 8.2 16.7 6.6 3.1 12.3 14.5 10.4 2.6 16.4 8.2 4.6 23.6 46.5 12.1 11.8 3.8 12.6 0.0 36.8 1.2 5.9 18.0 8.9 1.8 3.7 10.7 5.0 8.2 3.5 5.2 11.0 10.1 16.1 5.2 11.6 17.8 16.8 2.2 5.4 13.1 34.0 7.2 11.1 9.1 1.2 1.0 7.3 8.2 3.7 24.1 8.4 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 953.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 590000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 71.5 109.2 196.7 54.5 200.5 64.6 62.4 206.2 245.6 76.0 192.2 74.0 54.0 44.7 103.0 70.6 99.3 62.0 267.2 192.3 203.3 82.6 47.9 57.3 57.4 199.3 191.9 65.0 153.4 160.9 85.2 49.8 200.3 89.2 50.5 26.3 144.0 86.6 432.6 45.8 62.9 78.1 198.8 41.6 61.5 56.9 199.1 68.5 86.7 441.5 40.0 71.8 41.4 216.2 53.6 452.5 225.6 199.1 153.4 266.0 412.8 147.6 170.8 158.8 138.6 165.7 138.0 145.1 142.8 168.6 180.0 155.0 51.2 293.9 50.2 116.9 132.5 45.4 276.8 380.3 177.5 82.6 176.4 322.8 248.7 91.8 109.5 145.8 218.8 93.1 102.9 129.7 257.2 328.2 156.9 176.7 216.0 372.5 206.6 106.5 106.6 196.7 255.6 113.3 137.6 132.8 146.7 155.8 75.1 107.0 127.2 226.4 177.0 390.6 130.8 91.5 166.5 60.5 93.4 94.0 174.3 59.7 235.8 38.2 290.0 31.0 197.6 318.4 170.7 241.3 173.9 184.6 321.8 178.9 126.0 175.8 13.7 196.7 231.7 425.4 223.6 324.1 196.7 200.5 206.2 245.6 192.3 203.3 199.3 191.9 200.3 198.8 199.1 216.2 125.7 96.1 159.8 24.8 111.8 150.3 187.7 659.2 204.9 43.9 223.1 317.7 384.8 178.7 326.5 217.0 22.9 322.1 111.8 337.1 747.4 196.1 271.3 122.2 168.1 111.9 265.1 80.2 8.1 252.4 489.5 213.1 140.6 170.3 123.5 367.4 83.6 201.9 286.5 67.3 12.5 370.9 309.3 97.2 197.1 953.5 205.0 133.6 334.4 5.6 273.2 194.7 146.2 10.6 25.0 185.3 359.8 223.4 187.8 257.5 540.1 817.4 250.6 77.7 85.5 137.1 249.6 141.8 143.8 140.3 161.8 264.1 106.4 352.5 336.0 199.5 PIFO "C1orf88, FLJ23853, pitchfork" ENSG00000173947 "Primary cilia formation" Q8TCI5 1 111346600-111353013 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "fallopian tube: 174.2" "Group enriched" "Detected in many" 4 "Early spermatids: 430.6;Endometrial ciliated cells: 495.3;Late spermatids: 458.1;Respiratory ciliated cells: 990.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 3.4;RPTEC TERT1: 4.7;RT4: 5.9;SuSa: 7.9;T-47d: 3.8;U-87 MG: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.18e-3)" "unprognostic (3.23e-2)" "unprognostic (7.33e-2)" "unprognostic (3.03e-3)" "unprognostic (6.00e-2)" "unprognostic (7.43e-4)" "unprognostic (8.78e-7)" "unprognostic (6.43e-3)" "unprognostic (7.28e-2)" "unprognostic (9.07e-3)" "prognostic favorable (2.48e-4)" "unprognostic (3.32e-2)" "prognostic favorable (1.44e-4)" "unprognostic (6.03e-3)" "unprognostic (4.73e-2)" "unprognostic (6.37e-2)" "unprognostic (6.83e-2)" 1.0 2.8 8.6 0.7 9.1 0.1 5.7 8.2 9.2 4.3 36.5 5.1 0.6 7.4 12.5 3.5 174.2 3.5 9.3 8.5 10.8 8.3 0.0 12.9 0.3 14.3 15.0 3.3 6.4 15.1 9.8 2.9 13.7 12.2 1.1 5.1 3.1 6.0 0.1 1.4 1.1 4.7 12.2 0.4 4.4 24.8 10.8 1.7 15.0 0.9 0.6 5.4 0.8 14.0 0.0 0.0 0.5 0.6 0.6 0.7 1.0 0.0 1.2 0.2 0.0 0.8 1.1 0.0 0.2 0.0 1.1 0.0 0.8 0.2 0.0 1.4 0.2 0.0 0.1 0.9 0.4 0.0 0.0 0.4 3.2 0.0 0.0 3.4 0.0 0.2 0.2 0.1 2.0 0.3 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 4.7 5.9 2.2 0.2 0.0 0.1 0.1 7.9 3.8 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.4 3.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.4 0.2 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 9.1 8.2 9.2 8.5 10.8 14.3 15.0 13.7 12.2 10.8 14.0 0.3 3.2 18.5 3.3 0.5 4.2 9.1 71.5 1.8 0.7 6.0 12.6 17.3 0.0 83.2 5.5 4.2 11.6 0.1 0.0 21.5 13.0 430.6 495.3 5.8 1.6 3.0 0.0 0.5 2.0 4.4 3.7 1.5 9.0 0.0 3.8 0.7 0.1 1.2 0.0 1.4 0.0 77.3 0.0 0.7 458.1 5.9 1.5 8.8 0.0 0.0 11.8 0.0 0.5 0.6 1.2 0.0 3.4 0.4 6.2 0.0 36.3 990.5 5.4 6.6 4.6 22.8 127.1 10.5 0.5 2.8 7.0 1.0 8.4 0.1 4.3 PKDREJ ENSG00000130943 "Polycystin family receptor for egg jelly" Q9NTG1 22 46255663-46263343 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Cone photoreceptor cells: 4.2;Early spermatids: 2.5;Horizontal cells: 1.7;Late spermatids: 2.4;Spermatocytes: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA034587 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA034587: AB_10670570" "unprognostic (9.48e-3)" "unprognostic (1.09e-1)" "unprognostic (3.51e-2)" "unprognostic (1.25e-1)" "unprognostic (6.11e-2)" "unprognostic (5.06e-4)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (8.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-1)" "unprognostic (3.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.6 0.2 0.0 0.1 0.0 0.1 3.4 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.0 1.8 4.2 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.4 0.0 0.0 0.0 2.4 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 8.4 0.8 0.3 0.6 0.0 0.0 0.0 0.3 0.0 PLA2G4C cPLA2-gamma ENSG00000105499 "Phospholipase A2 group IVC" Q9UP65 19 48047843-48110817 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid metabolism, Phospholipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 78.8;skeletal muscle: 66.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 77.1;Cone photoreceptor cells: 66.7;Muller glia cells: 57.1;Oligodendrocytes: 137.1;Rod photoreceptor cells: 153.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 5.7" "Group enriched" "Detected in many" 4 "B-cells: 4.0;monocytes: 5.7" "Cell line enhanced" "Detected in many" "HHSteC: 13.1;TIME: 19.4" "Not detected" "Not detected" HPA043083 Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA043083: AB_10795714" "unprognostic (1.27e-1)" "unprognostic (3.88e-2)" "unprognostic (4.18e-2)" "unprognostic (2.82e-2)" "unprognostic (7.37e-2)" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (8.30e-2)" "unprognostic (1.94e-1)" "unprognostic (5.11e-3)" "unprognostic (1.90e-1)" "unprognostic (4.66e-2)" "unprognostic (9.45e-2)" "unprognostic (2.28e-3)" "unprognostic (1.87e-1)" "unprognostic (9.01e-2)" 5.1 17.3 13.8 5.5 23.8 0.3 4.3 20.8 20.5 4.6 4.5 6.5 6.3 8.6 3.0 4.3 5.1 5.8 25.1 14.1 18.2 6.1 4.7 8.0 10.2 24.8 23.5 1.7 4.9 12.8 6.6 5.1 26.7 6.8 3.3 78.8 4.1 8.0 66.7 6.4 8.5 10.3 14.3 11.2 3.3 2.8 21.1 4.7 4.9 41.2 5.6 5.1 2.6 41.5 0.7 1.3 0.0 0.3 5.7 3.0 0.1 1.3 8.5 1.4 3.4 0.0 2.1 0.0 1.8 3.7 2.7 0.3 0.0 0.2 2.2 0.9 0.2 0.0 0.5 1.3 13.1 0.0 1.9 0.6 0.3 0.7 5.7 2.6 4.9 0.1 0.0 8.0 2.2 2.2 0.1 0.2 0.1 1.0 0.1 0.1 2.0 0.8 2.7 0.6 0.9 0.1 1.5 2.9 7.1 4.3 0.8 2.2 19.4 2.2 0.8 2.8 1.0 0.5 1.8 0.2 1.9 0.0 4.8 0.0 2.1 0.0 0.1 5.7 0.4 4.0 0.5 0.0 1.2 0.9 0.0 0.0 0.0 1.1 1.4 0.8 0.1 1.4 13.8 23.8 20.8 20.5 14.1 18.2 24.8 23.5 26.7 14.3 21.1 41.5 7.2 3.2 1.7 30.7 2.4 2.8 1.0 1.5 1.2 77.1 2.4 2.9 35.3 5.7 0.5 0.0 66.7 0.2 0.6 1.2 1.9 13.0 0.3 0.5 4.6 14.3 0.0 0.0 31.6 2.9 0.2 7.4 1.1 0.7 0.0 0.1 4.6 2.0 5.6 33.7 34.7 1.6 18.3 1.2 11.1 0.2 0.6 4.9 7.2 15.0 3.1 57.1 1.0 25.1 137.1 2.7 1.4 7.9 0.7 2.5 5.7 5.2 0.2 153.8 13.1 18.0 9.9 0.9 1.0 0.2 3.0 0.1 1.1 1.6 0.3 0.4 PLAAT1 "A-C1, H-REV107, HRASLS, HRASLS1, PLA/AT1, PLAAT-1" ENSG00000127252 "Phospholipase A and acyltransferase 1" Q9HDD0 3 193241128-193277738 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 90.1;testis: 73.6;tongue: 44.5" "Cell type enriched" "Detected in some" 11 "Cardiomyocytes: 12.5" "Cancer enhanced" "Detected in many" "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 12.9;NTERA-2: 11.0;PC-3: 23.8;RH-30: 10.7;SCLC-21H: 22.0;U-2 OS: 13.3;U-251 MG: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051179 Uncertain Approved "Focal adhesion sites,Cytosol" No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" Cytosol "HPA051179: AB_2681375" "unprognostic (3.01e-2)" "unprognostic (4.21e-2)" "unprognostic (7.93e-3)" "unprognostic (4.82e-3)" "unprognostic (2.79e-1)" "unprognostic (1.87e-1)" "unprognostic (9.97e-3)" "unprognostic (9.68e-3)" "unprognostic (1.84e-1)" "unprognostic (3.55e-1)" "unprognostic (1.77e-4)" "unprognostic (5.09e-2)" "unprognostic (1.38e-5)" "unprognostic (1.61e-2)" "prognostic favorable (4.36e-4)" "unprognostic (2.98e-3)" "unprognostic (1.13e-2)" 0.9 2.5 4.6 0.2 4.9 0.1 1.8 3.5 6.0 0.4 0.8 0.6 0.0 0.9 5.9 6.5 0.5 0.2 9.3 5.1 6.0 0.7 0.1 0.2 0.0 4.5 4.3 0.2 1.4 2.1 2.2 0.1 4.2 0.1 0.1 9.0 2.0 0.7 90.1 3.3 0.3 1.3 2.3 0.2 0.8 73.6 3.9 2.2 7.0 44.5 0.3 0.3 0.4 4.5 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.4 0.0 0.1 0.0 0.2 0.0 5.3 0.0 12.9 0.4 0.6 0.0 5.6 6.9 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.0 0.4 23.8 0.0 10.7 0.0 3.7 0.0 22.0 4.1 1.5 3.3 0.0 2.1 6.5 0.1 0.1 0.0 13.3 0.0 18.6 0.1 0.0 0.0 7.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 4.6 4.9 3.5 6.0 5.1 6.0 4.5 4.3 4.2 2.3 3.9 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108959-45133354 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 195.8;Paneth cells: 104.7;Urothelial cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA025711: AB_1855320, HPA053665: AB_2732580" "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favorable (4.28e-4)" "unprognostic (3.34e-3)" 13.5 34.3 42.2 5.1 49.7 2.0 11.7 50.5 36.0 12.4 27.9 34.2 2.5 13.2 1.5 14.7 10.1 6.4 34.1 33.8 42.5 9.6 1.4 7.7 1.0 69.8 50.5 18.9 2.7 1.3 7.6 5.8 46.4 13.0 15.3 14.4 10.8 5.4 85.7 20.6 6.5 5.1 62.8 2.0 21.0 10.8 59.4 0.9 5.3 56.5 1.5 30.4 11.9 54.0 23.1 56.2 4.1 8.1 5.9 12.8 28.0 12.3 27.3 11.2 10.5 13.7 40.9 0.8 43.5 29.0 9.2 51.9 6.3 53.1 4.4 11.6 21.0 0.9 62.6 18.1 30.3 1.3 3.2 13.7 21.0 10.4 13.7 28.5 7.0 2.5 5.0 1.7 12.1 36.2 3.7 5.4 4.9 109.9 55.0 8.1 9.2 1.5 35.8 45.1 1.1 7.2 13.3 22.1 12.5 8.5 47.0 2.5 14.3 6.9 37.9 9.3 14.8 2.1 2.6 1.8 11.4 1.5 5.7 0.7 0.3 0.5 0.1 0.3 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.2 0.0 0.1 0.1 0.1 42.2 49.7 50.5 36.0 33.8 42.5 69.8 50.5 46.4 62.8 59.4 54.0 8.7 12.8 1.3 22.9 1.0 7.6 16.3 12.2 21.1 29.8 6.8 9.3 26.9 14.3 4.9 7.3 25.0 3.9 0.9 195.8 1.9 6.7 15.8 3.3 12.7 9.0 4.9 0.0 1.3 3.5 13.1 10.6 29.6 9.6 1.3 6.5 10.4 0.7 1.6 6.7 3.7 15.1 4.1 1.4 1.9 5.5 19.9 1.6 3.6 1.0 1.2 8.9 0.0 0.0 0.1 30.0 104.7 33.1 1.1 28.7 4.2 2.0 2.7 40.0 6.6 16.8 4.9 2.3 7.6 3.8 5.7 7.3 1.1 7.0 46.2 88.6 PLEKHG4B KIAA1909 ENSG00000153404 "Pleckstrin homology and RhoGEF domain containing G4B" Q96PX9 5 92151-189972 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.2" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 6.3;Club cells: 11.2;Collecting duct cells: 11.0;Glandular and luminal cells: 9.5;Respiratory ciliated cells: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 20 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "AN3-CA: 15.2;HAP1: 13.7;NTERA-2: 14.1;REH: 33.0;SCLC-21H: 14.0;SH-SY5Y: 12.6;SK-BR-3: 13.5;SuSa: 13.2;T-47d: 19.1" "Low region specificity" "Detected in all" "HPA036274, HPA058157" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA036274: AB_10669668, HPA058157: AB_2683625" "unprognostic (3.60e-2)" "unprognostic (8.52e-2)" "unprognostic (5.44e-3)" "unprognostic (1.48e-1)" "unprognostic (2.20e-2)" "unprognostic (3.91e-1)" "unprognostic (3.59e-1)" "prognostic favorable (3.47e-4)" "unprognostic (5.96e-2)" "unprognostic (7.08e-2)" "unprognostic (2.56e-2)" "unprognostic (1.58e-1)" "unprognostic (9.98e-7)" "unprognostic (1.43e-2)" "unprognostic (7.00e-2)" "unprognostic (1.63e-3)" "unprognostic (1.08e-3)" 0.1 0.1 1.9 0.1 1.1 0.6 1.5 0.5 0.5 1.0 9.2 0.4 0.2 0.8 0.1 0.3 1.1 0.0 0.0 0.9 1.1 2.5 0.0 0.6 0.2 0.8 1.2 1.0 0.4 0.1 3.5 1.4 0.4 1.8 0.0 0.2 2.6 0.3 0.1 0.5 0.1 0.2 0.8 0.1 1.0 2.9 2.8 1.0 3.1 0.0 0.1 0.0 0.4 1.6 0.0 1.4 10.1 15.2 0.0 0.0 0.2 1.1 0.3 1.0 2.2 1.8 0.2 0.2 3.3 1.4 0.9 0.6 13.7 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.4 0.0 4.1 0.0 0.0 0.1 0.4 0.2 0.0 14.1 0.0 0.2 33.0 7.1 8.6 1.2 0.0 14.0 12.6 7.9 13.5 0.0 13.2 19.1 0.0 0.1 0.4 3.7 0.0 0.3 0.2 0.0 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.9 1.1 0.5 0.5 0.9 1.1 0.8 1.2 0.4 0.8 2.8 1.6 0.1 0.0 3.4 0.3 0.0 0.4 3.8 0.1 0.0 0.4 6.1 6.3 1.6 0.0 11.2 11.0 0.0 4.6 2.8 0.0 0.0 0.4 0.3 4.8 3.7 0.7 0.0 0.0 1.0 0.2 3.7 1.0 0.0 9.5 1.3 4.4 0.0 0.0 0.7 0.0 0.6 0.2 0.0 0.0 0.8 0.3 0.3 0.4 0.0 1.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.1 14.0 0.2 0.0 0.1 0.9 2.4 5.9 0.0 0.3 1.8 0.3 0.4 0.0 1.0 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 202.0;skeletal muscle: 149.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.1;Astrocytes: 53.8;Cardiomyocytes: 39.8;Hepatic stellate cells: 42.1;Hepatocytes: 140.5" "Cancer enhanced" "Detected in many" "liver cancer: 9.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.9" "Cell line enhanced" "Detected in some" "AN3-CA: 2.3;BEWO: 3.2;RT4: 3.1;SH-SY5Y: 2.8;T-47d: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Lipid droplets" "HPA077050: " "prognostic favorable (7.68e-4)" "unprognostic (1.01e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-2)" "unprognostic (6.06e-3)" "prognostic favorable (2.81e-4)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (1.97e-4)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "prognostic favorable (2.16e-4)" 41.9 6.4 10.8 3.5 11.2 5.2 29.3 6.9 9.6 7.5 12.8 5.4 1.5 2.7 3.9 3.4 12.6 2.0 62.7 8.5 8.1 30.1 202.0 9.3 0.5 8.4 9.2 90.8 112.2 1.5 18.9 0.2 6.9 17.6 0.6 0.9 61.0 3.9 149.2 8.0 5.3 0.5 6.8 8.2 58.9 3.3 9.4 0.4 9.8 24.7 1.0 11.2 2.7 6.4 0.2 0.1 0.5 2.3 1.7 0.1 3.2 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.8 1.1 0.4 0.3 0.4 0.4 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.1 0.6 0.1 0.4 0.4 0.3 0.3 0.1 0.1 2.1 0.2 3.1 0.3 2.8 0.2 0.4 0.0 0.2 6.3 0.4 0.3 0.3 0.3 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.1 1.9 0.4 0.8 0.3 0.3 0.2 0.3 0.2 0.2 0.1 0.4 0.3 0.3 13.9 0.6 0.3 0.3 0.1 0.1 10.8 11.2 6.9 9.6 8.5 8.1 8.4 9.2 6.9 6.8 9.4 6.4 6.0 9.6 47.1 53.8 1.6 0.5 18.4 2.3 4.0 1.2 9.2 1.9 39.8 35.8 11.5 1.8 0.0 0.4 0.1 11.9 9.8 8.7 1.5 20.8 1.4 7.4 0.0 2.7 1.1 12.3 0.5 1.3 16.3 5.1 3.8 18.7 42.1 140.5 0.5 0.0 1.8 6.9 4.1 6.9 0.5 0.3 0.3 2.5 0.0 5.6 0.1 8.1 0.0 11.1 2.0 4.8 1.3 2.6 0.5 6.6 0.5 11.1 10.4 1.2 13.1 25.8 1.8 6.2 6.6 0.5 1.0 1.4 1.1 20.5 8.8 11.5 PLN "CMD1P, PLB" ENSG00000198523 Phospholamban P26678 6 118548296-118561716 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 1563.4;skeletal muscle: 507.3" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 2452.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005597, HPA026900" Enhanced NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB005597: AB_2252716, HPA026900: AB_1855314" "unprognostic (2.49e-1)" "unprognostic (5.67e-2)" "unprognostic (1.96e-3)" "unprognostic (4.81e-2)" "unprognostic (1.20e-1)" "unprognostic (5.54e-2)" "unprognostic (2.35e-3)" "unprognostic (4.66e-2)" "unprognostic (3.97e-1)" "unprognostic (8.98e-2)" "unprognostic (8.98e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.11e-4)" "unprognostic (2.98e-3)" "unprognostic (1.80e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.59e-4)" 40.1 12.3 1.5 12.3 3.0 0.6 15.9 2.9 4.0 31.7 2.0 148.7 13.6 121.7 21.8 43.9 81.9 92.2 1563.4 1.6 1.6 15.0 1.2 15.4 2.7 1.8 2.0 20.4 3.2 1.3 1.5 0.3 1.8 35.1 24.4 0.2 5.3 37.0 507.3 8.3 41.6 128.4 1.5 3.0 34.1 4.3 2.2 1.0 12.7 230.2 0.9 44.1 22.9 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 3.0 2.9 4.0 1.6 1.6 1.8 2.0 1.8 1.5 2.2 2.0 4.5 0.0 0.0 0.3 0.2 4.2 0.2 0.0 1.2 1.8 0.4 0.6 2452.8 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.0 108.2 0.2 0.7 21.4 0.0 0.0 1.0 0.0 0.0 49.1 0.5 0.1 0.0 0.1 0.7 0.1 0.1 0.0 0.9 0.0 0.0 0.0 4.7 25.0 0.9 0.4 3.6 1.0 0.0 0.0 0.0 2.0 1.1 0.1 0.0 11.7 0.0 0.7 0.0 0.0 0.0 0.3 276.1 16.7 248.0 9.2 0.8 0.3 1.6 0.0 0.8 0.0 0.0 0.4 PMPCA "Alpha-MPP, CLA1, INPP5E, KIAA0123, SCAR2" ENSG00000165688 "Peptidase, mitochondrial processing subunit alpha" Q10713 9 136410641-136423761 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021648, HPA063735" Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA021648: AB_1855491, HPA063735: AB_2685108" "unprognostic (9.80e-2)" "unprognostic (1.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.69e-2)" "unprognostic (4.01e-2)" "unprognostic (8.19e-2)" "unprognostic (6.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.97e-1)" "unprognostic (3.32e-2)" "prognostic favorable (8.00e-5)" "unprognostic (9.47e-3)" "prognostic favorable (2.14e-6)" "unprognostic (4.27e-3)" "unprognostic (1.57e-2)" "unprognostic (2.40e-1)" "unprognostic (3.54e-2)" 29.2 58.1 27.0 20.6 27.6 31.4 27.1 27.0 34.6 29.2 36.8 32.2 24.8 26.8 10.4 34.5 27.5 17.9 73.2 28.0 27.3 37.3 110.8 25.4 27.1 27.1 27.6 29.3 28.8 26.9 38.8 20.8 27.9 31.8 15.3 8.8 28.4 16.1 69.2 37.6 30.6 15.3 25.6 38.2 35.3 37.8 27.9 21.4 29.4 50.0 17.0 28.0 27.8 26.7 48.7 87.7 41.8 84.5 30.8 45.0 63.2 49.3 39.6 67.2 48.9 101.1 56.5 67.4 50.5 50.3 36.2 110.2 77.9 72.0 30.0 97.2 92.8 54.6 113.2 123.6 53.9 71.7 44.9 66.3 48.9 52.6 27.0 38.2 58.0 61.2 140.2 43.4 42.6 132.1 68.1 90.1 85.4 86.2 82.2 83.0 59.1 149.9 46.3 33.9 85.4 56.1 66.6 92.9 58.6 28.6 127.6 95.5 48.2 47.8 50.7 39.8 63.8 26.2 37.4 73.5 62.9 61.3 43.9 37.4 50.5 36.5 53.2 51.9 51.4 52.5 49.0 57.2 61.7 48.8 57.9 50.2 11.9 67.2 51.5 31.4 52.7 62.2 27.0 27.6 27.0 34.6 28.0 27.3 27.1 27.6 27.9 25.6 27.9 26.7 17.3 16.0 26.7 14.7 24.2 27.5 40.2 65.0 27.9 24.7 19.3 15.2 35.9 15.7 32.8 22.0 22.9 103.1 22.5 28.0 49.0 32.9 24.6 25.6 23.5 21.7 20.8 23.5 13.8 30.7 50.4 23.7 21.9 26.2 24.7 44.2 19.6 57.2 37.8 18.5 11.4 24.2 44.7 19.2 14.6 15.8 19.0 17.4 16.0 6.5 21.0 22.9 14.4 8.5 8.0 31.6 20.9 22.6 26.6 22.6 25.6 46.9 22.6 27.4 39.5 22.4 27.9 37.7 42.4 23.2 26.9 103.8 21.7 77.0 38.6 28.5 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924740-154936719 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 266.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved NA NA 15000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favorable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 39.9 56.4 99.0 29.8 100.1 15.3 35.0 97.9 108.9 33.4 95.0 39.9 45.9 25.9 17.7 77.7 37.2 17.2 63.1 93.9 96.4 53.8 91.9 30.1 34.6 98.6 97.4 35.8 41.6 58.2 60.3 23.7 96.0 32.4 22.2 19.8 34.0 27.1 79.1 69.2 44.2 27.7 96.4 45.7 40.5 26.6 102.3 27.9 31.5 47.4 36.8 31.9 37.9 99.8 51.8 72.9 46.7 72.5 43.6 30.9 48.5 40.5 29.3 38.9 37.0 30.6 101.0 75.1 75.9 49.3 40.5 49.4 65.3 63.9 17.8 103.3 28.9 34.1 104.1 29.0 40.0 51.4 29.3 36.3 58.7 70.2 49.6 19.5 40.0 65.9 36.8 221.7 41.3 108.3 40.8 51.0 41.0 121.7 95.0 60.3 29.8 171.1 66.1 38.4 37.7 91.1 44.1 75.7 51.9 35.0 146.7 91.1 32.7 35.8 29.2 84.4 62.1 174.0 153.2 131.8 58.9 83.9 46.7 28.0 80.9 91.8 68.2 205.6 110.1 114.8 93.1 70.6 93.6 111.1 59.1 59.1 6.9 59.7 219.4 96.5 134.3 80.0 99.0 100.1 97.9 108.9 93.9 96.4 98.6 97.4 96.0 96.4 102.3 99.8 22.7 57.7 37.5 9.4 42.2 69.8 105.9 95.8 51.8 38.5 67.1 68.3 57.3 78.6 42.2 53.3 8.4 235.7 31.5 65.0 266.1 69.6 9.0 45.0 28.5 29.8 66.4 35.6 5.1 71.3 108.1 45.1 46.9 44.2 22.2 49.8 39.3 146.9 141.0 37.0 7.0 78.9 67.1 67.9 49.5 13.5 42.6 47.8 65.8 3.7 49.5 119.1 41.2 8.0 11.8 61.7 61.7 47.8 58.8 53.7 219.3 246.1 22.1 27.4 32.9 46.0 48.4 51.3 51.3 81.0 90.5 227.7 45.1 162.6 79.9 76.2 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669733-153689010 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1;intestine: 81.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 40.9;Excitatory neurons: 29.0;Extravillous trophoblasts: 63.9;Granulosa cells: 46.9;Syncytiotrophoblasts: 49.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "AN3-CA: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.2 43.7 1.9 48.8 0.0 0.6 6.5 53.3 1.3 4.8 81.7 3.4 6.5 1.7 14.0 4.1 2.6 6.5 49.8 40.8 1.9 0.2 0.6 0.0 19.6 22.8 0.9 0.3 0.5 1.8 2.0 21.1 17.2 3.8 7.9 0.4 37.6 2.0 1.8 13.4 15.7 15.0 0.2 15.9 8.8 65.1 1.4 0.3 0.3 0.1 27.4 2.2 28.5 0.3 0.1 0.4 33.9 0.0 0.0 3.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.2 0.4 0.5 0.0 0.0 0.0 3.9 0.0 0.0 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.3 0.4 0.3 0.2 0.7 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.2 3.7 0.0 0.1 2.7 0.9 0.3 0.4 0.0 0.2 1.2 0.0 0.2 0.2 0.0 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.7 48.8 6.5 53.3 49.8 40.8 19.6 22.8 21.1 15.0 65.1 28.5 0.0 0.0 0.0 18.9 0.0 0.6 0.4 40.9 0.0 21.6 0.3 0.9 3.0 0.0 18.0 0.0 22.9 13.5 0.1 1.7 0.0 0.4 0.3 0.3 4.4 0.3 0.0 0.0 29.0 0.4 63.9 0.5 0.0 0.3 0.0 46.9 0.0 0.0 2.4 0.0 24.2 1.1 12.2 0.0 0.0 0.8 0.0 0.3 1.8 1.0 0.0 3.2 0.0 11.1 13.2 2.9 0.1 0.4 0.0 0.3 20.3 0.4 2.6 19.4 0.0 0.0 4.0 0.6 0.9 0.0 0.6 49.5 0.1 0.6 0.4 1.0 PNMA3 "MA3, MA5, MGC132756, MGC132758" ENSG00000183837 "PNMA family member 3" Q9UL41 X 153056409-153060467 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 37.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 42.1;Inhibitory neurons: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.2;SCLC-21H: 1.0" "Low region specificity" "Detected in all" HPA047920 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA047920: AB_2680210" "unprognostic (1.66e-2)" "unprognostic (8.97e-3)" "unprognostic (8.70e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (9.43e-2)" "unprognostic (3.10e-3)" "unprognostic (1.16e-1)" "unprognostic (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (6.20e-2)" "unprognostic (7.62e-4)" "unprognostic (1.93e-1)" "unprognostic (5.92e-3)" "unprognostic (2.93e-3)" "unprognostic (7.25e-2)" "unprognostic (7.84e-2)" "unprognostic (2.07e-2)" 0.2 1.3 4.3 0.8 5.2 0.3 0.2 1.5 9.4 0.3 0.3 0.4 0.2 0.3 37.3 0.3 1.6 0.2 1.4 5.0 5.4 1.4 0.4 0.4 1.5 5.5 3.6 0.5 0.3 0.6 9.3 0.1 5.4 0.5 0.1 2.1 0.3 0.4 0.1 0.4 2.2 0.1 2.0 2.5 0.4 8.9 5.9 0.5 1.2 0.2 1.3 0.2 0.3 5.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.2 1.5 9.4 5.0 5.4 5.5 3.6 5.4 2.0 5.9 5.5 0.1 0.0 0.0 9.4 0.3 0.3 0.0 0.0 0.0 7.5 0.2 0.4 2.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.3 0.2 0.0 0.0 42.1 0.0 0.0 0.2 0.0 0.0 0.0 3.5 0.4 0.0 0.1 6.7 38.6 0.0 0.0 0.9 0.3 1.4 1.2 0.4 0.0 3.7 0.1 3.4 1.0 9.5 2.7 0.0 0.0 0.4 0.2 0.2 0.0 3.8 0.0 2.9 0.0 0.0 0.3 0.1 2.1 0.0 0.0 0.0 1.0 0.7 0.0 0.1 PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818914-825573 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 508.1;breast: 361.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" Nucleoplasm "HPA055173: AB_2682725, HPA062602: AB_2684804, HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" 508.1 75.3 11.9 9.2 14.0 43.1 361.4 13.6 18.8 42.2 13.4 58.1 19.3 49.2 2.8 39.9 50.8 9.5 171.3 11.9 14.0 61.9 58.4 57.3 8.1 17.5 11.8 50.5 75.4 9.6 46.3 8.4 16.8 46.6 4.8 1.3 81.1 16.7 194.6 71.8 74.7 6.4 12.6 51.2 71.3 32.1 12.8 10.9 55.3 64.3 4.1 64.8 44.5 15.3 33.9 26.0 5.3 14.0 194.4 17.2 34.1 35.3 28.1 21.6 19.1 22.3 33.3 19.9 20.4 26.7 13.6 30.0 8.1 14.6 6.6 25.9 71.5 27.6 11.2 36.3 63.3 19.2 33.4 33.9 18.7 14.5 16.7 22.3 17.7 14.5 23.8 19.9 19.5 20.0 25.8 42.3 15.2 34.3 55.1 24.6 11.5 45.7 21.4 7.7 19.6 26.0 65.3 55.0 21.9 3.4 23.7 22.0 32.5 19.3 15.0 12.7 16.3 75.2 49.8 16.7 48.4 27.0 13.8 11.5 9.5 22.1 3.7 6.1 3.6 4.7 4.8 5.4 6.1 4.1 5.4 4.4 8.2 4.0 7.1 7.0 4.2 4.7 11.9 14.0 13.6 18.8 11.9 14.0 17.5 11.8 16.8 12.6 12.8 15.3 78.1 6.4 11.8 12.7 63.5 44.2 69.2 34.2 42.1 14.0 79.5 67.1 45.5 61.5 65.2 51.5 8.4 70.2 50.8 151.8 33.2 65.1 22.1 58.0 31.8 51.8 51.5 52.6 8.9 65.3 32.0 37.4 204.4 114.3 11.4 42.2 100.6 50.6 29.2 11.8 7.5 96.1 20.3 27.6 29.0 6.2 48.4 46.6 42.7 16.9 29.6 32.2 21.6 5.5 13.8 142.2 170.7 39.1 92.0 78.5 166.8 45.0 31.3 9.0 65.7 64.4 50.7 33.5 23.9 53.7 41.2 169.4 53.3 182.2 43.6 195.5 PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Proximal tubular cells: 126.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003656 Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.29e-4)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favorable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" 20.8 27.6 11.9 9.7 12.6 8.7 22.6 12.0 11.8 13.9 16.9 15.4 18.9 14.0 18.1 21.0 24.7 9.4 42.1 11.1 14.2 41.2 40.1 9.8 10.8 12.1 13.5 22.4 28.8 25.2 13.5 8.0 12.4 12.8 12.3 16.8 26.9 10.8 77.9 15.0 11.4 12.1 12.5 9.4 19.5 7.8 15.6 16.3 29.9 66.0 10.2 8.9 13.3 11.9 44.7 18.1 2.8 44.4 0.9 0.5 11.9 13.7 1.5 23.0 14.1 18.1 16.1 13.9 0.1 4.5 0.3 25.7 0.0 45.6 39.2 0.4 32.0 10.0 32.8 38.6 28.6 17.8 14.1 29.5 45.7 11.7 27.3 5.5 16.2 0.3 39.9 0.5 0.3 11.8 0.3 17.2 46.9 30.7 38.0 0.3 0.2 15.6 30.6 20.3 25.3 12.7 41.2 16.8 23.7 49.7 26.1 13.0 9.4 0.2 11.4 35.5 0.2 20.3 0.3 27.0 0.2 0.1 3.7 7.4 11.4 9.7 6.1 13.5 7.0 14.7 8.7 6.7 22.2 16.7 11.3 10.8 0.7 11.9 12.5 16.3 6.0 9.3 11.9 12.6 12.0 11.8 11.1 14.2 12.1 13.5 12.4 12.5 15.6 11.9 10.7 9.6 12.5 3.3 8.2 11.9 16.7 46.0 17.6 11.3 38.2 33.5 55.0 20.0 24.3 20.2 0.0 28.7 7.8 31.2 95.9 34.2 3.1 35.9 20.6 10.6 19.8 15.6 2.8 48.7 21.3 14.6 13.7 15.5 8.2 17.3 13.2 62.1 28.7 10.1 3.6 30.6 38.7 9.2 10.2 3.7 16.4 12.1 17.8 1.0 13.3 36.1 6.2 2.5 1.0 39.8 25.1 20.3 14.2 15.3 47.6 126.4 31.0 15.0 6.6 6.6 14.6 22.2 21.4 24.0 16.8 14.0 6.4 49.0 32.3 16.0 POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 254.5;Late spermatids: 133.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 280.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104, HPA069013" Enhanced Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB011616: AB_731977, HPA049104: AB_2680632, HPA069013: " "unprognostic (1.67e-1)" "unprognostic (2.68e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (4.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.31e-2)" "unprognostic (1.99e-1)" "unprognostic (4.57e-2)" "unprognostic (4.77e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-2)" "prognostic favorable (5.65e-4)" 12.4 17.5 26.6 13.5 27.4 51.3 27.4 82.3 35.5 18.9 24.3 12.3 10.8 12.9 19.7 26.5 13.2 17.4 26.1 28.1 29.0 18.0 33.9 14.2 20.2 27.1 27.8 20.4 16.9 18.8 26.7 11.1 28.9 24.8 13.2 18.0 30.3 11.3 85.3 23.1 10.8 10.6 27.6 17.2 14.0 53.1 30.2 24.8 14.2 70.0 22.2 30.8 18.9 28.9 40.2 23.5 40.6 80.4 21.8 20.7 33.8 25.2 29.3 41.5 37.7 33.1 46.0 36.4 31.1 16.5 43.4 20.0 34.1 29.5 50.3 23.8 36.7 26.5 18.2 45.3 34.1 18.6 280.6 18.8 34.4 30.1 35.4 51.8 32.1 77.2 58.4 22.4 40.3 23.6 78.0 52.6 54.4 48.4 26.7 44.2 40.8 31.4 78.4 32.1 22.7 41.8 29.9 19.9 79.0 41.4 52.5 31.5 17.8 19.1 27.0 48.8 24.6 32.5 58.4 52.2 19.3 39.4 52.2 47.6 15.1 48.1 12.0 18.8 13.3 12.2 12.5 13.0 15.7 11.1 14.1 13.3 63.6 22.2 26.3 84.9 19.3 11.5 26.6 27.4 82.3 35.5 28.1 29.0 27.1 27.8 28.9 27.6 30.2 28.9 13.9 3.2 13.6 6.8 20.2 16.8 30.1 14.2 31.3 2.9 14.3 15.1 21.6 7.2 20.7 7.3 8.4 7.5 51.9 3.1 5.9 11.7 254.5 13.8 7.7 12.5 6.0 7.6 15.8 9.6 7.0 9.7 10.2 9.9 23.4 12.7 8.6 12.7 7.4 6.7 20.3 5.4 4.1 5.7 9.9 133.9 7.2 18.2 7.2 19.7 11.2 8.3 13.4 12.5 16.7 33.6 5.8 3.8 21.9 41.6 4.3 6.8 16.4 4.4 0.0 6.6 12.3 19.4 15.4 27.3 20.0 11.1 16.2 7.8 6.6 31.6 POLR2I "hRPB14.5, RPB9" ENSG00000105258 "RNA polymerase II subunit I" P36954 19 36113709-36115213 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1145.8;Late spermatids: 2796.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035632, HPA045156" Uncertain Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA035632: AB_2674711, HPA045156: AB_10964748" "unprognostic (1.95e-2)" "unprognostic (7.88e-3)" "unprognostic (3.54e-1)" "unprognostic (7.41e-3)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (1.24e-2)" "unprognostic (4.12e-2)" "unprognostic (7.39e-2)" "unprognostic (4.69e-3)" "unprognostic (2.86e-2)" "unprognostic (8.16e-2)" "unprognostic (1.83e-1)" "unprognostic (3.36e-2)" "unprognostic (3.84e-3)" "unprognostic (1.08e-1)" "unprognostic (1.16e-1)" 32.6 41.0 97.6 23.3 104.3 44.4 34.8 104.2 118.6 30.6 85.8 35.0 28.9 28.4 39.7 40.2 55.7 27.2 78.9 94.6 100.8 32.9 40.2 25.5 31.5 98.5 98.6 50.0 83.9 61.3 26.1 21.8 101.0 30.2 20.2 25.9 66.9 35.9 195.2 41.5 29.9 21.7 98.5 29.7 31.5 66.8 97.4 30.4 37.2 119.7 24.2 28.3 15.7 120.6 96.7 364.7 61.9 103.8 38.5 44.6 67.7 35.5 47.5 80.5 67.5 179.0 62.0 61.6 80.4 38.2 46.8 49.6 60.4 82.5 42.1 107.8 115.5 59.1 88.8 180.9 70.0 88.7 53.1 47.5 71.4 51.7 75.1 51.1 52.8 112.2 66.6 117.1 48.5 292.1 124.6 111.0 74.5 201.6 151.7 130.4 51.6 114.0 94.0 121.3 145.0 74.0 60.1 172.5 59.5 53.7 81.3 92.7 35.7 88.6 91.6 60.3 128.2 83.2 88.4 99.6 102.3 88.0 94.7 130.7 109.5 128.4 113.9 115.2 130.6 168.7 148.3 134.1 90.2 134.8 150.4 117.2 72.5 111.0 113.0 223.8 176.5 114.0 97.6 104.3 104.2 118.6 94.6 100.8 98.5 98.6 101.0 98.5 97.4 120.6 108.2 83.3 66.3 2.9 62.9 79.0 94.9 156.4 75.1 63.1 203.5 279.4 253.5 133.0 124.7 163.7 25.0 144.5 76.3 141.5 352.1 178.2 1145.8 380.4 114.9 101.6 106.2 199.9 2.9 240.5 166.2 96.9 71.4 126.0 82.4 150.0 111.0 282.5 124.3 33.7 3.2 163.3 126.1 72.9 63.8 2796.6 139.1 68.7 168.9 0.0 122.5 183.2 77.2 1.5 7.9 196.8 196.8 154.2 88.5 127.9 221.4 528.2 386.6 73.6 111.7 111.1 125.1 378.2 183.1 155.9 109.0 103.8 68.1 133.7 167.7 90.1 PPARGC1A "PGC-1alpha, PGC1, PGC1A, PPARGC1" ENSG00000109819 "PPARG coactivator 1 alpha" Q9UBK2 4 23755041-23904089 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Activator, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.6" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1098.2;Inhibitory neurons: 1704.4;Oligodendrocyte precursor cells: 890.2" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "A-431: 88.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063136 Supported Nucleoplasm NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA063136: AB_2684948" "unprognostic (1.08e-1)" "unprognostic (7.47e-2)" "unprognostic (6.85e-3)" "unprognostic (2.28e-6)" "unprognostic (5.00e-2)" "unprognostic (1.15e-1)" "prognostic favorable (3.35e-6)" "unprognostic (3.04e-1)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (6.77e-2)" "unprognostic (4.58e-2)" "prognostic favorable (1.49e-14)" "unprognostic (3.62e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.07e-3)" 2.3 2.9 4.2 0.6 3.2 0.0 1.6 7.6 13.0 3.3 33.9 7.4 7.6 0.9 1.5 3.3 1.5 2.6 36.3 3.1 10.7 29.0 44.6 3.1 0.2 4.1 4.1 1.2 3.8 38.5 4.8 0.1 2.6 3.3 9.1 4.2 29.3 3.0 29.5 8.2 6.6 1.9 2.4 0.8 4.3 4.5 7.2 2.3 17.7 37.2 0.4 1.1 1.0 4.1 88.6 0.0 1.6 0.0 2.6 0.0 0.0 0.0 1.9 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.8 0.0 4.5 10.7 0.0 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.4 7.6 0.0 0.0 0.7 0.0 12.3 0.1 4.0 0.2 2.8 0.0 3.5 4.2 0.5 1.4 0.0 0.7 0.7 0.0 1.6 8.1 0.1 0.1 1.6 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.2 7.6 13.0 3.1 10.7 4.1 4.1 2.6 2.4 7.2 4.1 2.5 19.2 2.6 240.6 0.9 0.9 4.1 7.4 1.2 7.0 2.7 1.5 90.9 47.1 6.3 36.8 39.6 0.0 0.0 36.0 52.8 12.0 78.3 7.2 1.3 0.8 26.7 0.0 1098.2 0.0 0.0 2.4 4.1 9.7 1.3 0.2 1.1 88.8 0.0 0.0 1704.4 17.0 38.7 2.5 0.3 69.7 0.9 0.6 7.2 24.4 0.1 6.4 0.0 890.2 28.8 0.6 7.3 2.2 1.8 1.4 32.0 26.8 4.8 1.9 0.0 37.1 5.1 0.8 0.6 2.6 1.1 0.0 1.0 1.9 21.9 1.5 PPARGC1B "PERC, PGC1B" ENSG00000155846 "PPARG coactivator 1 beta" Q86YN6 5 149730298-149855022 "Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.8;Cone photoreceptor cells: 135.5;Rod photoreceptor cells: 72.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050543 Supported Nucleoplasm,Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Cytosol "HPA050543: AB_2681165" "unprognostic (2.86e-1)" "unprognostic (1.07e-2)" "unprognostic (5.09e-3)" "unprognostic (1.13e-3)" "unprognostic (2.63e-1)" "unprognostic (2.00e-3)" "unprognostic (4.51e-3)" "unprognostic (6.55e-2)" "unprognostic (9.14e-3)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.21e-1)" "unprognostic (9.01e-6)" "unprognostic (8.45e-2)" "unprognostic (5.09e-2)" "unprognostic (1.51e-1)" "unprognostic (2.77e-3)" 2.2 0.9 2.1 2.4 2.2 2.0 1.4 9.7 3.1 1.4 0.0 7.0 7.0 2.1 1.1 4.1 2.2 1.2 6.3 1.6 0.4 0.8 1.6 3.6 1.4 1.9 0.2 1.3 1.0 4.4 0.6 1.5 2.0 1.8 6.0 12.4 1.4 3.3 6.2 3.3 6.4 2.8 0.4 2.1 3.8 0.8 0.3 0.9 0.4 2.5 1.8 3.7 2.6 0.5 0.5 1.9 0.7 4.5 1.8 0.6 7.3 0.3 0.0 0.5 0.7 8.5 1.8 9.2 1.3 0.0 2.1 5.5 6.9 3.5 0.6 0.5 5.9 8.6 3.6 1.8 0.5 12.0 3.2 0.9 4.6 1.8 3.0 0.2 1.0 4.0 6.0 2.9 0.4 2.3 4.4 5.4 2.9 2.6 4.8 8.3 5.0 5.1 1.4 11.2 2.4 0.5 1.2 9.8 1.5 1.3 2.5 3.9 1.3 1.0 1.6 3.6 1.8 3.6 2.8 5.3 2.2 7.4 0.9 0.5 0.9 0.1 0.1 1.7 0.3 0.8 0.1 0.1 1.1 0.3 0.2 0.2 0.6 0.3 3.1 0.1 0.1 0.3 2.1 2.2 9.7 3.1 1.6 0.4 1.9 0.2 2.0 0.4 0.3 0.5 6.1 0.0 1.1 1.6 3.0 5.1 3.9 17.9 12.0 111.8 2.5 3.2 22.3 1.5 7.4 1.8 135.5 1.8 0.7 15.4 1.9 0.5 0.3 1.7 4.1 5.4 5.4 5.7 29.2 0.8 1.6 2.7 18.8 2.5 1.3 2.1 4.2 3.5 7.6 8.4 26.2 10.3 0.0 12.5 4.7 0.2 1.5 12.1 3.6 12.2 6.1 4.0 2.1 12.1 0.9 0.5 6.7 0.4 5.5 5.1 19.6 3.0 2.9 72.0 6.6 3.0 8.9 0.2 3.2 23.1 10.7 4.9 2.0 2.1 24.9 6.1 PPFIA4 ENSG00000143847 "PTPRF interacting protein alpha 4" O75335 1 203026498-203078740 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.8;heart muscle: 22.0;skeletal muscle: 18.9" "Group enriched" "Detected in some" 4 "Astrocytes: 12.7;Cardiomyocytes: 35.3;Excitatory neurons: 36.9;Inhibitory neurons: 31.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebellum: 58.8;cerebral cortex: 37.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 8.0;hTERT-RPE1: 13.1;RH-30: 13.6;U-266/70: 8.5;U-87 MG: 12.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053419, HPA054132" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA053419: AB_2682143, HPA054132: AB_2682393" "unprognostic (2.83e-1)" "unprognostic (2.34e-3)" "unprognostic (3.38e-5)" "unprognostic (3.19e-1)" "unprognostic (6.58e-2)" "unprognostic (5.36e-2)" "unprognostic (7.49e-8)" "unprognostic (4.65e-1)" "unprognostic (6.01e-4)" "unprognostic (1.29e-1)" "unprognostic (7.70e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.73e-8)" "unprognostic (6.82e-3)" "unprognostic (9.96e-2)" "unprognostic (1.11e-1)" "unprognostic (4.28e-2)" 0.5 0.6 9.5 0.4 4.2 1.0 0.6 58.8 37.4 3.5 0.0 1.4 0.5 2.3 2.4 1.1 1.0 1.7 22.0 7.6 0.0 5.3 0.3 0.8 0.2 2.2 0.0 0.9 0.1 0.4 1.6 2.8 1.5 1.0 0.2 7.2 1.4 0.6 18.9 2.0 0.8 1.2 0.0 1.6 0.8 3.2 2.5 0.4 0.5 12.0 0.2 0.6 2.0 3.1 8.0 0.0 0.1 1.9 0.0 0.3 0.3 0.4 0.9 0.7 3.2 0.4 0.3 0.4 1.6 1.8 0.2 0.9 0.6 1.5 1.5 0.0 0.6 0.1 0.0 0.0 0.1 0.0 1.0 2.5 0.1 0.4 0.0 13.1 0.0 1.6 0.1 0.3 6.5 1.1 0.6 1.0 0.9 0.0 0.3 1.4 13.6 2.3 0.0 0.0 2.6 3.3 0.8 0.2 1.1 1.2 0.2 0.6 0.0 4.8 2.8 0.1 0.1 8.5 0.2 0.1 12.4 0.7 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 4.2 58.8 37.4 7.6 0.0 2.2 0.0 1.5 0.0 2.5 3.1 0.1 0.0 0.0 12.7 0.1 0.0 0.1 3.7 0.6 5.1 0.5 0.3 35.3 0.0 0.9 0.0 6.2 0.1 0.1 0.0 0.0 0.9 2.7 0.4 0.3 0.6 0.0 0.0 36.9 0.0 0.4 1.7 0.0 0.7 0.0 1.8 0.7 0.0 0.3 6.7 31.9 0.1 0.0 0.0 0.0 3.6 0.3 0.7 0.0 4.7 1.9 1.5 1.0 5.5 1.9 0.4 0.1 1.9 0.0 0.1 0.0 0.1 1.0 1.5 0.0 1.1 0.8 0.6 1.4 0.3 0.0 0.3 0.1 0.1 0.0 0.0 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 370.9;Macrophages: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 62.7 227.7 42.7 42.8 48.4 168.8 42.4 57.9 69.6 27.6 63.7 50.0 36.3 14.0 7.2 66.0 22.9 19.5 119.1 38.1 45.2 63.3 174.9 29.1 32.3 49.0 56.2 19.3 86.9 77.6 18.3 27.1 48.8 18.8 52.4 8.9 39.5 45.5 99.5 71.9 31.3 21.0 50.6 58.7 98.2 35.0 57.1 28.3 26.0 133.6 55.5 60.0 35.1 60.8 220.4 90.6 62.3 123.5 57.0 73.6 79.8 124.2 161.2 265.7 249.6 213.5 102.7 224.8 68.0 87.4 188.6 127.8 195.3 115.4 410.5 72.2 186.4 352.8 87.5 380.7 96.4 245.7 80.4 173.2 81.3 264.5 262.3 86.5 47.5 86.4 351.6 268.3 91.6 111.7 64.1 204.2 53.0 99.6 500.6 109.8 96.4 114.7 103.9 200.0 124.1 92.0 63.6 253.8 97.9 40.5 111.4 187.2 43.5 116.1 106.3 137.9 242.0 124.7 137.7 181.9 114.5 313.9 32.0 15.2 34.3 18.0 10.4 27.5 10.9 19.1 9.1 9.6 43.3 7.7 8.1 7.9 75.0 9.0 10.4 5.4 10.0 16.6 42.7 48.4 57.9 69.6 38.1 45.2 49.0 56.2 48.8 50.6 57.1 60.8 8.4 6.4 6.8 7.2 32.7 42.6 30.2 23.8 31.3 4.0 41.8 40.8 124.6 14.3 14.4 12.9 6.2 99.4 26.4 39.9 92.0 42.1 14.5 12.4 24.0 10.1 21.6 37.0 4.1 28.0 127.1 25.1 78.0 15.5 13.4 73.4 6.1 98.5 91.1 8.4 5.7 69.5 18.3 40.3 370.9 14.1 6.2 160.8 35.6 4.7 32.0 13.0 5.2 5.5 15.0 39.8 26.6 6.0 48.7 41.4 21.3 41.2 12.6 5.2 19.7 18.2 28.6 14.8 22.5 52.9 37.6 142.3 23.9 60.2 81.1 34.2 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 18.8;skeletal muscle: 68.4;skin 1: 18.1;testis: 63.8;tongue: 25.6" "Group enriched" "Detected in many" 4 "Early spermatids: 123.6;Late spermatids: 281.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 67.9" "Lineage enriched" "Detected in many" 15 "dendritic cells: 67.9" "Cell line enhanced" "Detected in many" "T-47d: 19.5" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046045: AB_2679516" "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 1.1 2.6 6.3 1.0 6.6 0.7 2.2 5.9 6.5 2.3 3.8 1.2 0.6 1.9 18.8 4.6 2.8 1.0 8.7 5.8 5.7 7.8 0.7 1.6 3.3 5.2 7.8 2.3 1.7 5.5 2.6 0.5 4.6 3.3 0.6 6.9 2.8 2.1 68.4 18.1 1.4 1.3 4.5 1.4 1.2 63.8 9.1 2.3 3.1 25.6 2.2 1.1 4.0 3.9 2.7 0.1 1.5 1.7 0.8 1.5 1.1 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.4 0.8 0.8 4.9 1.1 4.6 0.4 0.0 2.6 0.8 0.2 0.2 0.9 0.0 0.2 1.7 3.0 0.9 4.6 1.0 2.1 0.2 1.0 0.0 1.2 2.9 0.0 0.0 1.6 1.4 2.3 0.1 0.1 0.0 2.7 0.1 0.8 0.2 0.6 4.3 1.3 2.2 19.5 0.0 1.1 0.3 2.8 0.0 0.2 0.1 0.0 0.0 2.3 0.6 2.6 0.0 0.3 0.0 0.0 1.5 0.1 0.7 0.0 0.1 7.1 0.7 0.0 0.0 0.0 0.0 4.3 67.9 0.0 0.8 6.3 6.6 5.9 6.5 5.8 5.7 5.2 7.8 4.6 4.5 9.1 3.9 1.2 0.0 0.5 0.3 2.0 2.2 4.7 8.7 10.2 5.7 4.2 4.6 5.8 0.0 2.7 1.8 10.4 1.0 41.3 0.7 9.8 3.2 123.6 3.2 0.3 1.5 0.0 0.0 1.8 4.3 1.4 1.1 1.1 0.6 0.0 5.6 0.7 0.1 0.7 0.0 1.5 0.9 2.0 1.3 11.5 281.6 3.1 2.0 0.0 0.0 1.6 25.4 0.0 0.0 0.2 2.1 2.4 2.6 0.0 6.7 0.3 0.6 1.8 9.1 6.6 1.1 2.8 2.8 16.9 3.5 2.8 0.5 0.9 3.2 0.8 2.9 PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 92.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 512.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 58.0;Karpas-707: 48.6;U-698: 48.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria No No "Cluster 24: B-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA020066: AB_1855628, HPA020862: AB_1855629, HPA023891: AB_1855630" "unprognostic (2.38e-2)" "unprognostic (5.86e-2)" "unprognostic (7.42e-3)" "unprognostic (6.70e-3)" "unprognostic (1.18e-1)" "unprognostic (1.17e-3)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (5.50e-2)" "unprognostic (1.41e-2)" "unprognostic (9.25e-3)" "unprognostic (6.56e-2)" "unprognostic (9.82e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" 5.3 8.5 23.3 14.9 26.3 9.9 14.5 22.5 31.2 19.4 22.0 5.9 4.4 32.7 7.6 11.2 21.5 8.9 92.5 26.5 23.9 17.8 7.6 9.7 25.6 19.9 22.3 32.5 11.1 12.5 9.9 9.7 22.9 16.2 6.0 14.2 11.8 7.1 14.2 2.6 10.4 26.6 22.1 18.9 8.0 19.9 27.7 15.2 7.9 11.5 25.8 8.9 11.7 33.2 4.6 1.5 5.7 10.1 8.3 10.9 2.3 7.2 13.0 23.3 27.4 11.6 1.1 58.0 7.7 4.6 11.5 0.5 17.0 5.4 9.1 44.9 7.1 10.8 5.0 10.8 6.6 14.6 5.3 7.2 2.7 14.5 12.5 4.9 4.2 25.4 15.5 48.6 7.0 6.5 20.3 7.9 3.4 3.5 2.3 10.8 9.3 21.9 8.1 2.0 4.4 3.9 4.6 0.5 5.4 9.6 23.2 3.9 0.8 8.3 4.2 2.8 4.1 15.6 15.0 48.3 9.1 11.7 14.0 24.7 9.9 8.1 39.4 12.0 51.4 102.9 37.1 39.9 18.6 113.5 36.3 44.2 3.2 27.6 3.6 131.3 46.9 24.5 23.3 26.3 22.5 31.2 26.5 23.9 19.9 22.3 22.9 22.1 27.7 33.2 20.7 48.1 12.4 105.4 124.8 9.8 15.8 5.7 29.6 109.5 42.8 25.7 512.1 8.6 13.7 49.7 18.8 11.5 153.0 0.8 156.5 7.0 7.9 9.7 37.2 27.2 9.6 34.3 89.5 6.2 3.2 42.9 8.2 20.0 19.0 32.2 24.7 30.2 28.9 85.8 145.6 16.5 4.1 14.5 16.4 10.5 23.9 27.5 21.4 40.3 75.6 21.8 80.3 100.0 54.7 4.6 9.2 31.6 82.7 32.1 8.2 47.6 19.5 14.8 26.3 38.5 36.4 38.2 22.9 71.4 5.4 2.9 70.1 45.4 4.1 6.7 PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 836.8;Excitatory neurons: 225.7;Granulosa cells: 438.3;Oligodendrocytes: 647.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Actin filaments" "HPA024171: AB_1854266, HPA024640: AB_1854265" "unprognostic (5.24e-2)" "unprognostic (8.59e-2)" "unprognostic (1.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.04e-1)" "unprognostic (5.45e-3)" "unprognostic (3.12e-2)" "unprognostic (9.13e-3)" "unprognostic (4.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-3)" "unprognostic (6.98e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" 40.0 11.1 5.1 36.0 12.6 8.3 17.8 8.9 9.9 51.8 15.5 151.0 24.1 222.0 30.5 150.1 52.6 72.5 356.9 5.5 6.5 14.3 8.4 24.8 18.6 17.2 15.3 38.3 7.2 6.2 5.0 34.4 18.0 142.8 64.8 7.6 20.0 198.6 84.1 11.0 30.9 246.4 16.2 30.8 41.5 7.1 9.2 7.7 10.9 80.5 15.1 86.7 23.0 27.3 2.2 4.4 3.3 3.2 4.6 3.3 5.4 1.7 1.7 1.8 1.7 1.9 3.9 2.5 0.8 3.2 4.3 7.0 5.0 2.7 1.9 3.3 3.1 2.5 7.1 1.2 1.1 5.4 2.8 2.6 3.0 2.5 2.6 9.1 1.5 2.8 3.9 2.9 3.1 1.7 4.1 3.4 2.3 2.4 0.9 2.6 8.5 3.7 1.4 8.1 4.0 3.1 3.3 3.9 1.9 4.4 3.4 2.4 1.9 2.5 1.5 1.9 1.5 4.2 4.3 2.7 2.4 4.4 10.2 2.4 1.7 1.5 1.6 1.0 1.4 2.0 1.1 1.0 1.5 2.1 1.3 1.0 16.2 0.7 1.5 1.7 1.7 0.5 5.1 12.6 8.9 9.9 5.5 6.5 17.2 15.3 18.0 16.2 9.2 27.3 12.5 12.8 19.8 181.5 6.0 17.3 49.0 35.6 8.6 59.3 11.1 20.6 836.8 11.5 23.0 12.9 75.0 18.1 8.6 52.9 11.7 10.1 39.2 19.3 16.1 15.2 24.0 5.2 225.7 12.9 8.4 51.4 17.3 7.6 18.9 438.3 16.4 9.6 9.4 26.9 205.0 17.2 63.1 23.5 10.9 13.1 12.2 8.2 8.8 102.1 7.8 10.2 5.2 102.5 647.4 6.3 21.1 51.1 9.6 24.3 12.8 7.1 27.4 30.4 32.9 38.6 162.7 19.3 13.9 7.1 10.9 25.4 10.7 14.2 33.9 28.4 PPP1R13B "ASPP1, KIAA0771, p53BP2-like, p85" ENSG00000088808 "Protein phosphatase 1 regulatory subunit 13B" Q96KQ4 14 103733195-103847575 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 106.1;Granulosa cells: 83.4;Inhibitory neurons: 105.9;Late spermatids: 78.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006394, CAB015454" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 14: REH - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "CAB015454: AB_2252775, HPA006394: AB_1079668" "unprognostic (1.20e-1)" "unprognostic (8.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.45e-1)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-2)" "prognostic favorable (1.41e-4)" "unprognostic (3.22e-3)" "unprognostic (5.13e-2)" "unprognostic (5.39e-2)" "unprognostic (1.62e-3)" "prognostic favorable (3.28e-11)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (1.97e-2)" "unprognostic (2.23e-1)" 7.0 4.7 3.4 3.2 4.2 0.7 7.4 6.6 8.5 6.8 4.0 7.7 7.1 7.6 2.1 11.6 9.8 4.7 21.2 7.6 3.9 6.9 5.0 9.9 2.7 1.2 2.0 10.9 8.3 7.8 6.5 6.0 1.7 10.7 5.6 8.0 10.2 5.3 7.5 12.5 7.6 5.2 0.3 11.3 10.1 19.1 3.8 2.0 23.4 6.2 5.1 8.0 7.1 4.2 4.9 4.2 0.5 5.4 0.9 0.4 1.9 3.2 2.3 4.0 1.8 3.3 4.4 1.1 11.7 2.2 4.9 9.8 5.8 3.7 3.5 2.2 4.0 0.0 1.3 5.7 3.6 0.5 4.4 1.0 4.4 0.3 4.7 1.7 7.9 2.8 0.7 1.7 2.7 20.3 0.0 0.5 1.0 12.3 5.1 11.3 3.2 2.7 7.8 12.7 6.6 16.9 9.9 7.3 2.5 2.6 18.4 0.7 7.1 2.9 4.0 2.4 3.0 4.0 5.8 8.4 1.8 2.9 1.4 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 4.2 6.6 8.5 7.6 3.9 1.2 2.0 1.7 0.3 3.8 4.2 35.1 19.2 39.5 31.0 7.1 13.5 16.6 6.9 18.8 15.8 31.3 20.6 45.4 14.3 11.8 7.3 12.5 2.9 11.9 26.9 3.9 7.9 58.0 37.9 7.9 30.3 15.6 2.7 106.1 6.4 1.0 7.7 37.8 48.5 0.0 83.4 14.3 9.0 2.9 15.2 105.9 14.2 6.1 1.6 5.7 78.4 4.4 3.0 3.6 49.6 0.4 5.8 1.0 31.7 33.2 6.8 18.7 20.3 6.3 13.1 14.6 7.8 8.3 12.9 6.6 10.9 6.7 17.8 15.1 24.1 12.9 2.2 9.0 8.7 15.8 13.7 PPP1R13L "IASPP, RAI" ENSG00000104881 "Protein phosphatase 1 regulatory subunit 13 like" Q8WUF5 19 45379638-45406349 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 179.4;heart muscle: 139.4;skin 1: 219.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.6;Granulosa cells: 118.3;Syncytiotrophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBEC3-KT: 130.1;hTCEpi: 189.0;hTERT-HME1: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005016, HPA041231, HPA059883" Approved Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005016: AB_2168576, HPA041231: AB_2677376, HPA059883: AB_2684151" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" "unprognostic (7.46e-2)" "unprognostic (2.92e-1)" "unprognostic (3.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.31e-3)" "prognostic unfavorable (3.39e-5)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.40e-4)" "unprognostic (2.52e-3)" "unprognostic (1.92e-2)" "unprognostic (1.55e-3)" "unprognostic (1.34e-1)" "unprognostic (7.69e-2)" "unprognostic (8.87e-2)" "unprognostic (1.02e-1)" 20.4 20.1 11.7 2.9 11.7 0.6 29.6 11.5 14.0 44.9 9.5 11.1 5.0 8.2 15.2 179.4 9.6 6.0 139.4 10.8 14.3 24.8 12.6 20.3 2.6 11.9 11.1 8.8 31.5 12.2 11.8 26.6 11.7 30.8 6.8 13.6 55.6 13.3 5.8 219.8 9.1 5.4 10.0 6.4 12.0 3.1 12.7 4.0 17.7 4.4 18.8 23.6 84.9 12.4 72.3 10.7 4.6 3.8 4.7 2.9 61.5 14.5 2.5 17.5 24.3 23.1 70.6 9.5 5.9 11.9 36.5 97.2 4.0 130.1 16.0 24.0 5.9 1.4 36.3 8.7 10.0 1.0 3.4 4.0 189.0 27.9 131.9 79.2 33.2 7.9 8.1 3.6 1.2 64.7 1.8 1.9 5.3 36.9 18.3 7.4 5.6 1.7 22.9 95.0 2.4 7.6 64.5 68.4 1.6 30.0 58.2 1.9 46.3 23.1 60.9 1.8 76.2 35.1 42.1 6.5 3.3 2.9 5.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.0 11.7 11.7 11.5 14.0 10.8 14.3 11.9 11.1 11.7 10.0 12.7 12.4 14.3 35.3 13.0 9.4 2.0 68.7 85.6 38.4 67.2 1.7 21.9 28.6 38.8 20.0 27.8 20.2 10.4 83.2 2.5 17.8 5.9 34.9 0.7 8.7 3.0 13.4 7.2 10.1 0.8 15.8 37.7 5.6 8.6 17.1 4.5 118.3 11.7 2.5 7.6 0.0 0.9 6.9 14.2 1.6 5.0 0.5 5.9 2.2 12.4 9.4 1.9 2.4 2.1 2.5 1.6 50.4 17.2 12.4 6.1 44.2 22.6 3.9 16.3 26.8 6.6 8.4 14.1 2.7 2.1 81.2 71.0 128.5 2.5 2.8 9.0 63.4 PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 75.5;skeletal muscle: 66.5;skin 1: 97.2;thyroid gland: 58.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 280.2;Cardiomyocytes: 79.5;Skeletal myocytes: 80.9;Suprabasal keratinocytes: 336.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 40.7;HBEC3-KT: 86.1;HEK 293: 36.2;hTCEpi: 103.0;hTERT-HME1: 41.1;RPTEC TERT1: 35.5;SK-BR-3: 37.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB044667: , HPA047907: " "unprognostic (1.81e-3)" "unprognostic (7.65e-2)" "unprognostic (4.25e-3)" "unprognostic (6.92e-2)" "unprognostic (3.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.81e-3)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (5.13e-2)" "unprognostic (4.50e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (7.49e-3)" "unprognostic (6.77e-2)" 0.4 0.2 5.1 1.4 6.6 0.2 6.0 5.9 8.0 10.2 6.0 12.5 10.4 1.4 0.9 18.4 16.0 0.1 75.5 7.8 5.0 9.5 0.0 12.3 0.3 5.6 5.4 0.1 0.7 5.1 1.7 3.4 5.6 1.3 8.6 0.6 3.2 0.2 66.5 97.2 2.7 0.9 4.4 0.1 0.8 6.7 5.0 0.5 58.7 8.5 5.8 0.5 22.0 5.0 27.9 0.1 11.7 0.1 0.1 0.6 0.0 3.7 0.0 0.0 0.1 1.3 3.8 0.7 8.0 5.3 1.8 40.7 6.1 86.1 0.0 0.0 36.2 0.3 0.0 0.0 0.0 0.0 1.1 0.0 103.0 0.2 41.1 0.0 0.0 0.5 23.6 0.0 0.0 3.8 0.0 0.0 0.4 0.0 0.2 0.7 0.0 0.0 35.5 1.5 6.2 0.0 0.6 37.7 2.2 0.7 0.2 1.9 0.0 0.1 20.4 32.5 9.5 0.0 0.0 0.0 14.2 16.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.6 5.9 8.0 7.8 5.0 5.6 5.4 5.6 4.4 5.0 5.0 0.3 19.2 41.1 1.3 0.5 280.2 17.9 19.6 12.0 1.1 6.5 4.3 79.5 0.0 17.1 14.7 0.0 0.1 0.4 24.5 1.9 3.8 0.2 37.9 0.6 3.0 28.2 0.0 28.0 0.2 0.1 6.7 0.0 5.1 1.3 4.1 0.0 0.0 3.0 1.7 13.3 3.1 14.2 0.0 19.7 1.6 0.0 0.6 30.2 2.8 1.1 0.0 0.0 37.2 2.5 12.8 41.5 0.4 0.0 16.6 5.0 38.6 61.5 0.5 0.0 80.9 4.3 0.5 1.8 14.7 336.6 1.9 1.4 0.5 8.7 1.9 PPP1R16A "MGC14333, MYPT3" ENSG00000160972 "Protein phosphatase 1 regulatory subunit 16A" Q96I34 8 144477969-144502121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 208.9;Proximal enterocytes: 440.8;Proximal tubular cells: 404.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MCF7: 49.9" "Low region specificity" "Detected in all" HPA023755 Uncertain Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA023755: AB_1854268" "unprognostic (9.63e-2)" "unprognostic (4.51e-2)" "unprognostic (5.45e-3)" "unprognostic (3.11e-1)" "unprognostic (5.60e-2)" "unprognostic (3.75e-2)" "unprognostic (4.64e-3)" "unprognostic (2.65e-1)" "unprognostic (3.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (1.29e-2)" "unprognostic (1.03e-1)" "unprognostic (9.45e-2)" "unprognostic (2.79e-2)" 6.1 15.0 10.2 4.7 8.6 3.8 8.2 4.3 15.0 10.5 16.7 25.1 27.1 10.5 1.6 9.8 18.9 3.1 9.6 12.9 8.9 26.7 23.5 10.8 2.9 10.2 10.4 7.9 17.7 7.4 36.9 1.7 7.1 15.5 2.4 2.9 11.6 5.6 6.3 9.0 24.6 1.6 8.1 8.0 14.1 33.3 10.3 2.4 27.0 1.0 1.0 9.1 6.7 5.1 30.4 24.3 3.9 15.1 1.6 2.7 19.3 8.2 5.1 6.3 5.1 6.4 21.2 5.0 21.1 3.0 5.6 19.8 2.0 6.7 1.0 10.3 11.9 6.0 26.4 6.8 4.7 4.3 7.9 2.7 8.9 7.3 2.1 4.1 4.5 8.2 24.0 6.1 2.3 49.9 15.3 19.9 7.4 15.6 30.3 15.9 1.9 10.1 5.7 10.0 12.5 23.9 14.9 13.7 13.0 1.0 32.3 9.1 7.7 7.1 33.2 19.8 15.8 4.0 4.3 1.8 22.8 8.3 6.5 0.0 0.8 0.0 1.0 1.2 0.9 0.8 0.8 1.0 1.2 0.1 0.5 1.1 0.2 0.2 1.7 0.7 0.6 0.8 10.2 8.6 4.3 15.0 12.9 8.9 10.2 10.4 7.1 8.1 10.3 5.1 7.9 3.2 15.4 28.1 6.2 43.2 36.2 47.6 54.1 25.0 78.3 82.0 85.8 157.3 24.6 40.5 14.6 7.2 6.0 135.9 121.3 33.7 12.6 43.8 15.6 13.3 51.6 6.1 7.8 41.6 24.3 13.3 70.3 24.2 3.8 16.4 12.8 208.9 6.1 30.3 7.6 98.1 26.4 7.0 27.1 14.4 22.7 9.8 8.8 5.6 3.8 102.8 5.2 6.6 2.8 29.3 109.8 15.4 5.9 40.0 440.8 404.2 59.8 50.9 6.6 17.2 17.3 52.9 28.7 77.8 61.8 6.7 7.1 69.2 116.0 28.3 PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 259.7;skeletal muscle: 831.6;tongue: 271.1" "Cell type enriched" "Detected in many" 4 "Distal tubular cells: 1348.0" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.8;NTERA-2: 29.4;RPTEC TERT1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007811, HPA041542" Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "CAB007811: AB_598171, HPA041542: AB_2677542" "unprognostic (6.39e-3)" "unprognostic (2.61e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (2.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.71e-3)" "unprognostic (1.76e-3)" "unprognostic (2.88e-3)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (8.49e-3)" "unprognostic (7.49e-2)" 241.3 2.6 37.1 1.1 73.6 0.3 169.8 26.1 45.7 1.6 20.4 29.6 3.0 2.2 0.7 10.3 3.8 1.5 110.9 38.9 36.9 259.7 138.1 1.0 0.5 29.0 32.0 7.7 14.2 20.8 1.8 0.0 26.0 7.9 1.8 14.6 9.7 3.2 831.6 7.6 13.2 3.3 25.5 0.5 27.8 2.2 31.6 0.2 2.6 271.1 0.5 5.4 1.5 34.1 0.0 0.0 3.9 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 5.4 0.0 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 0.0 0.2 32.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 73.6 26.1 45.7 38.9 36.9 29.0 32.0 26.0 25.5 31.6 34.1 7.9 0.0 0.0 3.3 3.4 0.1 0.0 0.0 0.0 2.2 23.7 40.6 300.7 5.7 0.0 18.4 0.0 0.0 0.5 0.0 1348.0 3.5 1.6 10.4 0.5 4.6 2.4 2.7 3.1 0.4 0.1 24.5 0.0 13.8 0.0 21.0 6.4 218.4 0.6 112.7 1.8 2.1 0.0 3.8 0.0 1.9 1.2 1.6 0.0 0.0 0.0 3.7 0.0 0.0 0.5 2.5 0.1 1.2 0.0 0.3 0.5 156.8 0.0 2.8 0.0 19.2 21.6 0.2 5.9 0.0 0.3 0.0 0.9 4.2 2.0 0.2 PPP1R1C Inhibitor-1-like ENSG00000150722 "Protein phosphatase 1 regulatory inhibitor subunit 1C" Q8WVI7 2 181954241-182131398 "Predicted intracellular proteins" "Cell cycle, Cell division" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 21.1" "Group enriched" "Detected in many" 4 "Early spermatids: 168.5;Late spermatids: 219.8;Spermatocytes: 145.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055043 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA055043: AB_2797251" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.54e-3)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.57e-2)" "unprognostic (6.59e-3)" "unprognostic (1.13e-1)" "unprognostic (7.98e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-3)" "unprognostic (7.68e-2)" "unprognostic (3.07e-2)" "unprognostic (9.75e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 21.1 0.3 1.0 0.0 0.8 0.1 0.0 0.7 0.8 0.0 0.3 0.0 0.4 0.0 1.4 1.0 0.0 1.8 0.0 0.0 3.7 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.7 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.4 0.4 0.3 1.0 0.7 0.8 1.4 0.1 0.1 0.3 0.1 12.8 8.7 6.2 0.0 0.3 0.6 1.2 2.8 1.1 0.3 0.3 40.6 17.2 8.1 3.7 0.0 3.1 0.0 0.5 1.9 2.5 168.5 1.7 0.1 0.6 6.1 0.0 1.1 11.0 6.6 2.4 4.6 0.8 0.0 0.0 0.0 18.5 0.6 0.0 19.4 0.4 10.2 0.8 0.0 219.8 5.9 0.3 3.6 1.9 3.6 12.0 0.0 3.5 0.7 23.1 0.1 0.7 0.0 0.3 0.0 0.7 1.6 1.7 0.0 0.4 0.8 145.1 2.6 1.3 0.3 2.5 0.0 0.8 0.6 1.0 PPP1R3A "GM, PPP1R3" ENSG00000154415 "Protein phosphatase 1 regulatory subunit 3A" Q16821 7 113876777-114075920 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 64 "heart muscle: 40.8;skeletal muscle: 152.9;tongue: 104.1" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 157.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 67 "THP-1: 14.6" "Region enriched" "Detected in single" 12 "thalamus: 1.1" "Not detected" "Not detected" "HPA070440, HPA073138" Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA070440: , HPA073138: " "unprognostic (8.96e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.0 0.0 152.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 104.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.8 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPP1R9A "FLJ20068, KIAA1222, Neurabin-I" ENSG00000158528 "Protein phosphatase 1 regulatory subunit 9A" Q9ULJ8 7 94907202-95296415 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" "Astrocytes: 294.1;Excitatory neurons: 262.8;Inhibitory neurons: 201.5;Oligodendrocyte precursor cells: 593.1;Oligodendrocytes: 308.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 6.8;NK-cell: 10.3" "Group enriched" "Detected in many" 9 "granulocytes: 6.8;NK-cells: 10.3" "Cell line enhanced" "Detected in many" "HAP1: 12.2;RH-30: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027726, HPA075591" Approved Approved "Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA027726: AB_1855653, HPA075591: AB_2732296" "unprognostic (1.05e-1)" "unprognostic (6.59e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (8.62e-2)" "unprognostic (6.19e-2)" "unprognostic (1.45e-1)" "prognostic favorable (7.17e-4)" "unprognostic (2.26e-2)" "unprognostic (1.89e-1)" "prognostic favorable (8.63e-6)" "unprognostic (2.74e-1)" "unprognostic (4.85e-2)" "unprognostic (8.47e-2)" "unprognostic (8.79e-3)" 1.7 7.0 13.0 0.9 20.1 0.2 4.9 6.0 14.5 2.7 0.3 8.2 1.7 3.0 4.9 1.6 5.7 2.4 5.2 14.4 7.5 4.7 0.4 3.7 0.3 5.9 6.9 3.3 8.8 6.7 4.6 2.5 8.0 2.3 3.8 18.5 9.6 2.8 4.9 0.5 2.2 2.2 6.6 1.8 4.9 6.7 10.2 0.5 6.6 4.9 0.3 2.6 0.5 13.9 0.0 11.0 6.6 7.6 0.0 0.0 5.3 0.5 0.1 1.0 0.8 6.1 3.7 0.0 9.0 0.5 0.6 0.0 12.2 0.0 1.2 0.0 4.5 11.4 4.5 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.8 4.8 0.1 0.0 5.5 4.9 1.8 0.0 11.8 0.0 10.7 9.2 7.3 7.4 0.0 0.9 1.4 4.0 2.1 0.0 0.0 0.1 4.4 0.1 4.0 7.3 11.5 0.0 0.2 0.0 0.9 6.8 0.0 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 10.3 0.1 0.3 0.0 0.1 13.0 20.1 6.0 14.5 14.4 7.5 5.9 6.9 8.0 6.6 10.2 13.9 4.5 41.7 66.6 294.1 2.4 0.4 0.9 0.0 0.6 58.2 24.4 12.2 127.7 18.6 16.5 47.8 56.3 21.6 3.3 15.7 3.9 25.1 17.9 40.3 4.5 6.8 38.9 2.5 262.8 7.0 3.1 9.4 21.4 57.1 5.7 39.5 7.9 1.5 1.7 1.7 201.5 15.0 4.1 0.6 0.3 15.3 2.5 0.8 7.2 41.2 0.0 46.9 3.1 593.1 308.4 6.6 14.4 0.7 2.7 4.8 1.8 9.6 20.6 88.9 0.0 118.4 9.2 25.1 12.6 0.5 0.9 33.1 1.7 22.9 15.7 2.6 PPP2R3A "PPP2R3, PR130, PR72" ENSG00000073711 "Protein phosphatase 2 regulatory subunit B''alpha" Q06190 3 135965728-136147894 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 51.2;skeletal muscle: 180.5;tongue: 117.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.3;Oligodendrocytes: 201.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 37.4;BJ hTERT+: 35.3;RPTEC TERT1: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035829, HPA035830, HPA065338" Uncertain Approved "Golgi apparatus" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA035829: AB_10696513, HPA035830: AB_10670121, HPA065338: AB_2685475" "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.71e-1)" "unprognostic (4.04e-1)" "unprognostic (1.44e-4)" "unprognostic (9.43e-2)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (8.92e-2)" "prognostic favorable (1.15e-5)" "unprognostic (4.55e-2)" "unprognostic (3.06e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.91e-4)" 3.1 3.4 3.3 2.3 7.2 0.2 7.1 4.3 5.0 5.2 3.9 8.0 2.0 7.7 5.1 8.3 4.1 5.0 51.2 4.2 4.9 22.0 1.1 3.9 0.6 5.7 5.5 5.6 3.4 11.7 1.8 2.8 5.3 5.9 5.4 2.6 8.9 6.5 180.5 18.9 2.3 9.6 4.3 1.1 7.4 7.2 6.0 0.6 3.1 117.6 1.2 4.5 4.0 13.7 37.4 2.0 10.3 5.0 8.1 10.2 11.9 28.5 35.3 13.2 16.3 2.4 2.4 0.1 10.7 29.3 9.5 4.7 4.3 10.0 28.3 0.1 1.4 1.6 1.0 0.1 5.8 0.0 1.4 9.3 8.5 16.8 7.8 13.3 12.8 1.0 1.0 0.1 19.2 6.2 0.3 0.2 7.2 0.4 6.9 0.1 15.1 0.1 46.2 1.4 0.7 5.7 4.7 5.7 10.9 9.2 9.1 0.5 8.4 13.7 7.5 18.8 12.7 0.4 1.0 0.1 10.1 0.8 4.9 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 3.3 7.2 4.3 5.0 4.2 4.9 5.7 5.5 5.3 4.3 6.0 13.7 7.9 28.9 27.6 51.6 2.8 26.4 19.5 7.1 19.4 5.7 19.9 15.5 115.3 8.6 10.0 55.2 0.0 10.9 6.7 25.3 21.5 20.6 8.4 9.9 19.0 11.4 13.1 0.4 35.2 9.9 15.4 14.8 21.9 16.1 3.8 15.7 8.6 2.9 2.5 3.3 47.2 6.9 6.1 2.4 9.8 10.7 24.5 3.2 28.4 13.1 9.6 8.9 2.1 72.4 201.1 17.2 10.6 18.4 1.5 17.8 21.7 40.1 8.1 2.6 6.6 29.0 14.0 10.1 18.6 15.3 33.2 10.4 3.4 6.7 8.9 15.6 PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.6" "Cell type enhanced" "Detected in all" "Late spermatids: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA051066: AB_2681333" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (3.93e-2)" "unprognostic (8.54e-2)" "unprognostic (9.08e-3)" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-3)" "unprognostic (9.99e-3)" "unprognostic (3.56e-2)" "unprognostic (2.96e-1)" "unprognostic (4.89e-1)" "unprognostic (1.93e-1)" "unprognostic (9.23e-2)" 22.8 35.9 46.0 9.8 48.1 8.7 19.3 48.6 50.6 15.1 54.1 29.0 25.2 12.6 16.3 25.8 11.3 9.8 101.4 45.8 46.9 27.0 71.5 12.7 9.2 47.6 47.3 11.0 41.6 21.2 23.1 8.2 47.4 19.3 21.4 15.5 29.1 14.7 126.6 20.6 22.1 14.8 46.7 23.6 27.1 31.3 49.0 11.0 17.9 107.1 9.9 23.1 16.3 46.4 21.7 16.6 16.2 31.3 49.3 19.2 22.6 37.8 15.1 32.5 18.7 46.6 20.6 23.3 20.2 38.0 29.3 19.5 25.8 22.7 23.0 36.2 28.2 36.7 21.4 35.2 15.3 20.3 33.7 25.0 13.5 29.2 15.4 9.4 30.5 39.0 32.4 46.1 37.8 41.9 51.7 34.0 5.2 93.7 74.2 31.0 68.6 71.8 18.6 19.0 34.5 12.3 18.1 42.5 15.7 17.3 22.5 15.7 18.9 37.6 16.6 32.9 31.8 52.2 43.9 22.3 24.0 39.6 15.7 15.6 35.0 35.4 24.8 84.3 20.1 17.5 23.8 23.6 36.3 21.8 22.3 19.5 5.0 39.2 105.3 73.3 31.1 48.2 46.0 48.1 48.6 50.6 45.8 46.9 47.6 47.3 47.4 46.7 49.0 46.4 21.7 9.6 4.6 10.1 11.0 15.6 11.3 34.5 4.6 15.2 23.3 23.9 62.6 15.7 20.0 14.7 8.4 25.7 25.4 44.7 72.4 23.3 57.3 12.1 9.3 17.7 32.3 4.2 6.9 46.9 47.2 20.4 13.7 6.0 28.6 4.8 30.7 63.0 49.1 11.8 6.9 47.7 44.7 25.5 14.0 144.3 16.8 19.3 16.0 1.9 7.2 31.4 21.6 6.0 7.0 23.2 31.2 16.1 29.2 10.7 101.4 65.2 15.8 28.3 32.9 19.1 19.1 61.5 21.1 30.1 24.0 13.5 9.7 27.2 50.2 15.4 PRDX5 "ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10" ENSG00000126432 "Peroxiredoxin 5" P30044 11 64318121-64321811 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 2430.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008661, HPA037915, HPA037916" Enhanced Supported Mitochondria NA NA 6900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB008661: AB_1620988, HPA037915: AB_2675735, HPA037916: AB_2675736" "unprognostic (2.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (9.43e-2)" "unprognostic (6.71e-3)" "unprognostic (1.08e-3)" "unprognostic (3.11e-1)" "unprognostic (9.30e-2)" "unprognostic (1.07e-3)" "unprognostic (1.57e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.24e-5)" "unprognostic (8.19e-2)" "unprognostic (2.30e-1)" "unprognostic (9.63e-2)" "unprognostic (5.03e-2)" 181.8 400.3 346.0 112.7 342.6 285.7 170.1 375.9 429.4 227.2 480.2 346.6 213.3 153.7 176.6 448.5 400.3 120.7 467.4 340.4 384.6 377.1 280.3 217.2 110.1 382.8 373.3 246.0 224.9 254.5 313.3 164.1 387.0 165.5 299.6 109.0 286.2 164.4 504.0 181.1 226.1 97.1 365.2 162.9 313.9 150.1 377.8 167.7 354.5 439.6 137.8 192.5 244.8 346.4 225.3 453.4 267.9 444.5 284.3 424.4 308.5 274.9 442.3 199.8 247.4 332.9 451.8 329.2 467.0 447.4 712.6 503.5 253.3 589.4 125.8 456.6 200.8 333.3 728.8 386.3 581.0 127.8 271.3 432.4 757.2 334.9 337.8 387.6 308.4 380.6 191.5 755.6 285.5 572.0 220.9 547.8 402.6 356.5 573.9 210.9 274.5 1178.8 760.1 442.9 224.7 424.9 230.8 506.8 818.8 254.3 370.5 283.3 298.3 281.8 258.6 326.7 123.1 383.1 490.8 392.4 340.7 253.7 223.6 703.9 465.4 630.7 251.0 432.9 218.3 393.5 229.0 205.1 369.8 409.0 224.5 225.9 802.3 368.5 399.0 487.9 297.1 639.6 346.0 342.6 375.9 429.4 340.4 384.6 382.8 373.3 387.0 365.2 377.8 346.4 213.7 266.0 463.4 17.6 182.1 326.5 760.2 1591.9 405.2 159.0 266.2 435.9 617.6 371.8 931.2 450.6 70.9 1122.2 185.8 846.1 1612.1 788.4 79.6 865.2 221.3 204.7 801.9 200.6 12.4 1039.2 1144.0 296.1 365.4 285.9 104.7 299.8 205.6 405.2 476.9 92.5 14.0 1041.6 1072.1 206.5 261.0 294.9 279.0 210.8 435.8 8.4 339.7 309.6 278.1 14.1 15.3 1487.3 641.3 226.8 288.9 401.3 922.4 1468.5 2430.7 150.3 197.2 176.2 433.1 150.2 333.9 482.8 257.7 978.9 165.2 713.3 1231.7 1077.1 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645314-56715335 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.8;skeletal muscle: 38.7;tongue: 36.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 328.5;Excitatory neurons: 109.4;Inhibitory neurons: 119.0;Oligodendrocyte precursor cells: 84.9;Rod photoreceptor cells: 115.5" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "Golgi apparatus" "HPA044540: AB_2678977" "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavorable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favorable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 1.4 1.4 2.0 0.5 3.5 0.0 3.3 3.0 3.5 1.4 4.1 5.0 0.5 1.8 1.1 4.7 2.7 1.9 40.8 3.9 2.1 13.6 0.7 1.4 0.1 0.9 1.3 1.5 1.8 8.3 1.3 0.5 0.9 3.8 1.4 13.5 4.3 2.6 38.7 0.7 1.3 3.1 0.3 1.3 2.2 1.1 1.3 0.4 3.3 36.4 0.1 1.8 1.3 1.5 0.0 3.8 2.1 0.0 0.7 0.5 2.3 1.9 1.5 2.5 4.3 3.9 4.9 0.0 0.6 0.6 7.5 0.1 8.0 0.0 7.1 0.0 8.8 0.0 7.0 5.5 0.0 0.0 0.1 0.6 0.0 3.5 0.3 5.8 0.8 2.0 0.0 0.0 1.1 0.1 0.0 0.0 5.6 0.0 5.5 0.0 0.0 0.0 14.1 1.3 2.0 5.5 6.0 0.1 0.0 6.0 3.3 0.0 0.0 1.5 2.3 2.8 6.6 0.0 0.0 0.0 4.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.5 3.0 3.5 3.9 2.1 0.9 1.3 0.9 0.3 1.3 1.5 1.1 9.6 4.8 30.7 2.0 0.9 8.0 6.7 2.2 42.0 19.4 9.5 328.5 24.3 14.3 49.7 50.1 1.0 0.2 6.1 54.8 9.5 3.9 14.4 2.9 10.3 14.4 0.0 109.4 4.8 0.4 15.3 5.1 17.4 2.5 11.7 9.7 8.1 0.1 26.9 119.0 6.3 8.2 0.0 1.6 4.8 6.8 1.4 5.4 18.7 0.0 18.6 0.0 84.9 20.4 6.2 3.0 29.3 0.0 21.2 0.2 82.4 10.7 115.5 6.6 24.5 17.2 7.2 3.7 17.7 0.4 0.4 1.2 5.3 6.1 13.4 PRKAG1 ENSG00000181929 "Protein kinase AMP-activated non-catalytic subunit gamma 1" P54619 12 49002274-49018807 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 339.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077805 Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA077805: AB_2686855" "unprognostic (3.24e-2)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.45e-1)" "unprognostic (4.68e-2)" "unprognostic (1.93e-2)" "unprognostic (5.35e-2)" "unprognostic (8.49e-2)" "prognostic favorable (1.83e-4)" "unprognostic (3.40e-1)" "unprognostic (2.57e-1)" "unprognostic (1.97e-2)" "unprognostic (5.57e-2)" 42.8 54.5 36.4 29.8 40.5 47.4 50.5 39.9 46.3 37.6 41.9 40.7 32.6 32.9 59.1 44.2 33.4 31.3 80.9 38.2 38.6 50.5 49.4 30.8 38.7 34.5 35.5 25.6 37.4 59.1 33.9 35.1 36.5 37.7 47.8 42.3 36.1 39.9 122.7 43.0 29.9 44.8 33.5 28.6 33.5 33.5 34.9 41.8 37.7 112.4 50.8 40.1 30.8 41.5 79.8 45.8 50.5 76.3 157.8 141.6 33.2 85.5 117.4 84.4 55.7 50.9 66.1 50.4 72.9 98.9 53.9 65.4 42.5 115.6 80.4 69.6 57.1 70.4 66.5 34.2 120.2 97.7 54.6 110.0 94.6 65.9 141.4 123.6 90.3 67.6 60.1 70.0 108.6 52.8 45.8 31.5 29.1 339.6 96.8 24.1 53.3 59.7 114.0 67.6 42.1 57.7 61.0 99.1 142.5 39.7 134.1 49.5 72.5 44.4 52.3 87.7 63.5 109.1 113.3 36.0 89.3 69.9 34.5 87.3 59.8 59.9 53.0 58.7 50.0 51.9 46.1 47.6 68.7 51.3 41.3 43.0 70.9 71.8 56.0 45.2 66.8 73.0 36.4 40.5 39.9 46.3 38.2 38.6 34.5 35.5 36.5 33.5 34.9 41.5 20.2 9.6 22.7 16.6 31.2 20.0 30.3 64.5 11.4 29.2 24.3 20.8 49.8 18.6 29.9 36.8 37.5 65.6 30.5 24.5 76.3 48.3 11.3 11.4 21.3 21.9 21.0 30.3 18.1 46.4 57.7 26.7 15.8 12.9 21.5 31.4 30.4 23.2 52.2 15.2 24.1 31.6 63.1 36.2 26.5 15.7 36.7 26.7 37.4 9.4 55.5 41.6 55.6 23.1 21.1 47.8 16.5 27.1 25.0 24.2 38.6 69.3 19.2 30.1 19.7 18.5 27.5 49.3 43.9 19.1 26.0 67.0 26.3 33.6 32.2 23.6 PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347417-162727775 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 28.3;tongue: 15.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 4.8;Distal tubular cells: 19.6;Proximal tubular cells: 6.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 2.0;HEL: 4.1;HSkMC: 1.7;Karpas-707: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" Cytosol "CAB016257: AB_628104, HPA036012: AB_2732471" "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.69e-3)" "unprognostic (9.85e-2)" "unprognostic (5.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-3)" "unprognostic (8.16e-2)" "prognostic favorable (6.75e-12)" "unprognostic (9.93e-2)" "unprognostic (1.51e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-1)" 3.4 3.3 4.1 0.1 3.6 0.3 1.9 0.4 5.7 1.3 0.6 2.7 1.2 1.6 1.2 3.2 1.2 1.5 9.1 4.6 1.8 5.2 1.2 1.0 0.5 1.0 1.9 2.8 1.2 2.3 1.8 0.4 1.6 1.2 0.6 1.5 1.3 1.4 28.3 2.0 1.0 1.2 1.0 1.0 1.9 5.3 1.9 0.5 1.3 15.9 0.3 2.5 1.0 2.4 0.0 0.0 0.3 2.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.5 4.1 0.1 0.6 0.3 0.0 0.0 1.7 0.0 0.0 0.2 0.3 0.0 0.2 0.2 2.2 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.7 0.0 0.0 0.5 1.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 1.7 0.3 2.2 0.8 0.1 1.3 0.6 0.8 0.9 0.7 1.6 1.8 1.8 0.5 0.6 0.4 0.0 0.1 0.8 4.1 3.6 0.4 5.7 4.6 1.8 1.0 1.9 1.6 1.0 1.9 2.4 2.3 9.6 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.0 0.0 1.8 1.8 0.0 0.5 0.4 0.0 19.6 1.1 0.0 3.4 1.8 0.7 0.0 0.0 0.0 2.2 0.1 1.8 0.0 3.2 2.5 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 6.8 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.4 3.7 0.0 0.0 PTCD3 "DKFZp666K071, FLJ20758" ENSG00000132300 "Pentatricopeptide repeat domain 3" Q96EY7 2 86106223-86142157 "Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041154, HPA041382" Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA041154: AB_10795488, HPA041382: AB_10795695" "unprognostic (1.16e-2)" "unprognostic (4.47e-2)" "unprognostic (1.37e-2)" "unprognostic (9.30e-3)" "unprognostic (2.40e-2)" "unprognostic (2.54e-1)" "unprognostic (4.92e-3)" "unprognostic (2.06e-2)" "unprognostic (4.78e-2)" "unprognostic (3.78e-1)" "unprognostic (7.42e-3)" "unprognostic (5.49e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.77e-4)" "unprognostic (3.69e-1)" "unprognostic (7.79e-2)" "prognostic favorable (6.86e-4)" 10.0 15.8 13.1 7.6 14.2 14.7 9.9 15.2 15.9 11.6 16.3 12.6 10.1 11.7 10.2 10.7 11.7 6.4 26.2 13.3 14.5 12.4 16.5 9.6 11.8 13.6 14.0 15.1 10.7 13.1 14.8 9.2 14.7 10.4 13.5 13.2 9.8 7.5 32.8 10.3 11.9 9.0 13.7 12.0 11.8 16.6 13.5 10.5 12.0 36.3 11.1 10.3 10.7 16.7 16.2 37.6 22.0 18.5 16.1 16.6 26.2 32.6 13.8 18.0 18.0 69.9 15.1 39.7 11.8 17.1 18.6 28.9 44.7 17.7 22.9 17.8 37.0 31.8 23.0 59.2 16.3 26.0 23.1 19.8 12.8 13.7 24.4 18.8 15.7 28.6 33.5 14.8 16.0 15.0 21.7 31.0 20.2 31.5 23.9 28.8 30.9 30.6 24.6 31.7 23.9 14.7 15.2 25.0 30.4 20.6 13.2 15.7 11.3 14.2 15.1 14.6 19.2 33.7 47.6 31.6 13.8 29.4 11.1 4.4 9.6 7.6 12.4 7.0 14.6 15.3 11.2 13.2 10.6 16.4 15.1 11.3 0.3 14.3 14.1 10.7 13.9 8.8 13.1 14.2 15.2 15.9 13.3 14.5 13.6 14.0 14.7 13.7 13.5 16.7 17.1 57.7 33.5 50.3 31.0 26.0 26.3 27.7 34.7 61.7 19.2 16.8 105.7 18.6 37.4 23.9 66.7 53.0 30.6 21.7 25.4 18.8 34.8 27.5 33.3 23.5 31.1 39.5 52.9 11.9 27.0 30.5 30.1 24.2 33.6 47.5 21.4 41.7 21.7 37.0 53.1 25.3 20.3 19.6 13.3 22.4 27.1 17.7 8.8 21.5 22.7 49.8 28.8 48.7 53.4 15.0 19.2 19.5 26.4 23.7 23.2 30.1 26.2 65.3 13.1 36.3 21.3 98.3 62.4 28.7 24.7 36.7 31.8 47.9 38.5 20.4 PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261902-96336995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 10.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" Nucleoplasm "HPA016852: AB_1855878" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (7.48e-2)" "unprognostic (5.68e-3)" "prognostic unfavorable (1.08e-5)" "prognostic unfavorable (9.83e-4)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-3)" "unprognostic (4.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.55e-2)" 1.6 2.2 1.6 3.4 2.0 4.9 3.1 1.2 2.6 3.5 0.8 3.4 4.1 2.1 2.8 3.7 2.5 3.1 7.2 1.8 1.0 3.7 4.6 2.6 5.6 0.5 0.6 3.6 2.7 8.0 0.6 4.6 1.3 1.9 2.9 0.9 2.0 3.5 2.9 3.2 3.2 3.6 0.2 2.6 1.4 1.9 2.0 3.6 4.5 3.0 5.2 2.6 1.1 1.4 14.9 11.6 2.0 5.5 4.2 8.5 3.4 10.6 15.5 10.6 7.5 4.6 4.2 24.9 9.5 10.5 2.1 6.0 14.1 11.1 16.1 12.5 10.3 24.5 19.8 2.5 4.3 17.8 8.1 7.2 10.9 14.4 10.2 2.7 7.0 7.6 12.5 12.3 9.7 4.4 14.0 3.0 3.1 5.1 11.1 10.9 10.1 18.8 5.7 12.5 8.6 3.5 3.9 3.4 1.4 2.3 8.2 6.3 11.8 9.1 5.5 6.3 12.3 2.5 13.3 11.8 5.7 19.3 7.5 10.5 2.6 1.5 1.7 1.6 2.5 1.7 2.8 2.2 4.0 2.2 2.5 1.8 0.9 3.2 1.7 1.2 1.7 6.7 1.6 2.0 1.2 2.6 1.8 1.0 0.5 0.6 1.3 0.2 2.0 1.4 12.4 19.2 9.1 8.8 50.5 31.6 18.9 22.6 42.7 10.2 22.9 18.4 94.5 14.3 15.6 11.0 10.4 78.4 23.6 11.9 1.9 20.5 60.1 6.6 9.1 22.9 5.4 38.3 29.3 44.9 54.1 18.0 14.8 9.3 32.4 17.6 34.2 32.1 45.9 5.0 29.2 17.1 10.2 45.3 31.5 52.2 23.3 36.0 19.6 15.9 39.3 4.7 29.9 21.1 8.7 23.9 11.9 25.9 45.5 21.4 16.6 19.0 5.2 4.7 0.0 13.8 15.8 12.1 18.8 33.1 33.5 80.9 34.3 14.6 34.8 16.3 PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 4898.3;testis: 3242.2" "Group enriched" "Detected in many" 11 "Leydig cells: 38051.3;Peritubular cells: 65156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1386.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1386.8" "Group enriched" "Detected in some" 6 "HHSteC: 518.7;HSkMC: 252.0" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" NA NA 2500000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "CAB009916: AB_2174617, HPA004938: AB_1855745, HPA067456: " "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" 391.1 297.1 1849.2 247.1 2423.8 9.9 121.1 2440.1 2559.6 1675.5 1508.4 84.8 31.5 320.4 735.9 172.5 492.1 396.7 4898.3 1760.9 2034.8 466.5 80.2 607.8 824.1 2339.4 2228.2 66.8 113.2 9.1 398.4 227.8 2318.0 727.0 17.7 146.1 97.8 813.1 108.3 164.9 205.9 99.7 1999.6 317.5 93.0 3242.2 2264.9 127.4 55.1 60.0 306.0 230.3 1181.0 2580.3 0.1 0.0 0.1 0.0 5.4 16.7 8.8 0.3 0.0 0.0 0.0 0.0 0.2 0.6 4.0 24.0 0.0 0.8 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.3 518.7 0.3 1.3 252.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.0 0.2 0.0 0.0 6.6 0.9 8.2 0.0 0.1 0.2 1.6 0.0 0.0 1.6 2.0 0.0 0.6 0.0 0.1 0.6 68.3 0.7 0.2 0.2 2.1 0.1 0.3 0.0 0.1 3.9 0.0 0.9 0.0 0.3 0.4 50.5 1.0 3.4 0.3 4.3 6.3 1.8 0.2 0.9 9.9 2.3 3.8 0.2 1386.8 1.4 11.2 1849.2 2423.8 2440.1 2559.6 1760.9 2034.8 2339.4 2228.2 2318.0 1999.6 2264.9 2580.3 29.3 0.0 0.6 665.0 1.5 70.4 3.2 0.1 5.7 46.8 6.6 14.7 333.6 8.6 0.1 138.0 52.1 14.4 1863.6 0.2 68.4 0.3 215.9 29.7 1156.5 167.8 0.0 13.5 4.0 0.0 55.0 1584.0 1.1 20.1 1.3 0.3 46.1 1.6 57.3 21.9 12.8 0.0 0.0 3.4 161.8 1230.9 38051.3 57.0 209.9 176.1 4.6 4625.8 583.9 63.3 850.4 1.7 0.0 65156.8 6.0 20.7 0.0 1.1 0.0 130.3 164.3 787.4 124.8 130.7 111.1 12.0 80.1 35.4 61.3 0.1 0.0 14.5 PTGES2 "C9orf15, FLJ14038" ENSG00000148334 "Prostaglandin E synthase 2" Q9H7Z7 9 128120693-128128462 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 700.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020631, HPA020733" Approved Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA020631: AB_1855887, HPA020733: AB_2670508" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (5.13e-3)" "unprognostic (2.56e-1)" "unprognostic (1.57e-1)" "unprognostic (7.10e-2)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.83e-7)" "unprognostic (2.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" 18.1 49.8 31.6 15.6 33.9 6.5 16.0 29.1 45.8 18.1 32.4 30.6 27.5 21.6 4.0 35.3 17.6 11.4 95.0 35.6 33.0 36.4 37.7 14.8 17.6 31.5 31.5 16.1 37.6 35.2 41.4 9.7 32.1 24.6 9.2 10.0 26.1 16.8 117.9 20.9 23.8 7.5 27.3 21.1 29.6 14.5 31.5 11.9 23.5 78.7 9.7 22.3 22.0 31.7 46.1 114.0 15.5 54.4 13.5 12.8 47.9 30.7 20.6 48.6 24.9 86.9 75.6 43.5 45.7 15.9 36.9 108.8 22.5 47.1 6.5 28.3 62.3 21.0 92.7 79.5 41.0 42.1 39.5 18.6 32.3 39.5 26.9 14.2 31.6 47.8 50.2 26.4 16.7 130.0 56.9 75.6 42.7 58.7 113.9 39.6 26.5 111.6 32.8 33.1 69.1 45.6 47.3 86.3 34.2 6.7 78.7 23.5 34.0 46.3 50.2 62.8 63.1 48.9 25.5 38.3 39.1 33.2 44.5 1.4 3.3 0.7 3.1 3.7 3.8 3.8 2.2 3.5 4.3 2.7 2.4 3.0 0.6 2.7 1.8 5.8 3.1 1.9 31.6 33.9 29.1 45.8 35.6 33.0 31.5 31.5 32.1 27.3 31.5 31.7 18.8 16.0 6.4 10.4 32.0 22.9 38.1 32.7 25.0 37.8 34.2 36.3 700.2 51.5 25.9 23.9 20.9 82.1 30.8 86.1 146.8 74.6 2.1 12.7 20.9 29.4 45.1 13.2 15.5 51.8 62.1 32.7 46.4 17.3 14.7 31.9 13.9 37.8 57.6 37.0 15.8 62.2 46.8 25.3 43.6 4.8 30.7 30.8 56.9 3.7 105.7 21.9 38.1 12.1 7.2 57.6 60.4 21.8 45.4 68.0 93.4 99.3 9.3 44.8 19.7 17.8 37.2 3.6 45.6 48.3 24.6 66.6 25.6 84.1 105.5 52.9 PTGR2 "FLJ39091, ZADH1" ENSG00000140043 "Prostaglandin reductase 2" Q8N8N7 14 73851844-73886827 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 41.9" HPA001125 Approved Approved Vesicles NA NA 36000 "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA001125: AB_2666207" "unprognostic (3.82e-2)" "unprognostic (2.79e-2)" "unprognostic (6.05e-2)" "unprognostic (3.26e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (8.10e-3)" "unprognostic (6.99e-3)" "unprognostic (5.96e-1)" "prognostic favorable (4.55e-12)" "unprognostic (4.42e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" 6.9 12.2 10.4 2.8 11.5 0.9 9.1 11.1 12.1 4.8 11.6 7.2 12.1 4.6 17.2 5.0 12.0 5.2 27.1 9.9 11.7 18.9 19.1 5.6 3.1 11.8 11.9 7.4 5.3 10.6 7.6 2.4 12.1 9.1 5.7 10.7 6.7 5.4 32.8 6.9 8.9 2.6 11.3 3.4 6.2 6.2 10.6 3.0 12.6 32.1 2.6 4.2 4.1 13.9 8.9 11.9 9.6 4.7 7.6 16.3 7.6 3.0 4.1 3.6 5.6 6.8 21.2 0.9 6.8 3.0 8.4 8.8 8.7 6.5 6.6 6.7 4.1 6.2 5.5 3.0 3.8 2.3 2.2 7.7 15.1 5.5 4.4 7.8 1.8 6.1 8.3 1.8 8.2 12.7 6.2 5.9 10.7 11.9 11.6 7.6 3.7 1.5 19.7 8.6 12.7 11.0 7.7 8.1 9.8 9.1 41.9 3.7 2.7 5.3 10.0 3.9 6.6 10.2 4.7 2.8 8.3 5.5 7.2 6.7 1.1 0.9 0.6 0.4 0.6 1.0 1.1 0.5 1.3 1.0 1.8 1.5 0.8 1.3 1.2 1.5 1.1 1.0 10.4 11.5 11.1 12.1 9.9 11.7 11.8 11.9 12.1 11.3 10.6 13.9 4.5 19.2 13.0 10.7 2.9 6.8 12.8 16.7 6.2 8.9 8.4 5.5 43.2 8.6 12.9 18.4 14.6 6.3 2.0 8.6 25.4 11.7 2.4 21.5 5.8 5.2 4.8 4.2 8.0 8.7 2.5 6.1 5.1 7.3 3.8 9.3 3.3 14.3 7.4 33.7 10.3 10.0 10.2 5.5 3.1 2.0 7.2 4.3 8.8 5.6 4.0 22.3 6.2 7.1 20.4 8.7 11.1 6.8 2.9 7.2 24.8 18.4 31.6 20.8 6.6 9.9 6.1 42.1 18.8 3.5 6.7 4.0 2.9 17.3 11.7 7.7 PTP4A3 "PRL-3, PRL-R, PRL3" ENSG00000184489 "Protein tyrosine phosphatase 4A3" O75365 8 141391995-141432454 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 640.3;pituitary gland: 207.5;skeletal muscle: 738.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.9;Cardiomyocytes: 272.8;Cone photoreceptor cells: 123.0;Rod photoreceptor cells: 226.5;Smooth muscle cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.0;non-classical monocyte: 54.1" "Group enriched" "Detected in all" 6 "granulocytes: 55.0;monocytes: 54.1" "Cell line enhanced" "Detected in many" "HDLM-2: 128.7;Karpas-707: 45.9;RPMI-8226: 38.1;U-266/84: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA003281: AB_1855903" "unprognostic (1.09e-1)" "unprognostic (3.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.10e-3)" "unprognostic (2.08e-1)" "unprognostic (6.18e-2)" "unprognostic (3.61e-2)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (2.50e-1)" "unprognostic (5.73e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.81e-5)" "unprognostic (2.25e-1)" "unprognostic (1.12e-2)" "unprognostic (2.28e-2)" "unprognostic (1.77e-1)" 48.6 16.6 11.4 2.0 9.8 0.7 43.3 9.0 14.1 87.3 9.2 70.7 2.1 69.9 3.0 15.1 67.2 1.4 640.3 10.1 10.6 48.9 9.8 58.4 1.1 10.5 10.3 46.8 116.2 2.6 207.5 2.3 10.7 73.6 0.7 36.0 29.9 2.1 738.1 22.8 37.4 4.4 9.3 56.8 99.7 22.0 13.3 1.1 35.2 62.1 1.3 40.5 35.7 9.2 0.3 0.9 0.6 0.1 0.0 0.2 0.1 0.5 0.1 0.0 0.0 0.1 2.3 0.0 9.8 0.1 0.1 0.0 0.1 0.1 0.0 128.7 1.9 5.2 0.2 1.8 0.5 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.4 1.0 3.1 45.9 0.1 11.3 0.7 0.2 2.1 1.0 0.7 19.3 0.1 38.1 0.0 0.1 11.4 3.9 0.6 0.1 2.6 1.2 1.8 0.0 0.5 0.1 2.2 0.1 0.0 11.6 42.0 0.3 0.1 2.8 0.1 1.5 3.3 12.5 3.1 28.2 1.8 5.1 5.8 3.0 2.0 1.2 6.5 3.4 55.0 1.5 54.1 8.6 5.3 5.1 11.4 9.8 9.0 14.1 10.1 10.6 10.5 10.3 10.7 9.3 13.3 9.2 52.7 3.2 44.5 5.5 21.1 9.9 5.2 23.7 7.4 102.9 9.8 7.4 272.8 4.3 8.3 7.3 123.0 0.3 5.6 0.8 9.8 8.2 10.9 2.0 3.1 57.7 10.2 0.8 5.3 62.9 0.3 21.7 5.6 2.0 1.3 6.6 15.0 0.3 4.1 15.2 10.3 2.9 26.4 2.8 20.1 7.1 3.7 4.0 21.4 8.4 12.8 36.7 2.1 2.5 0.7 10.8 0.2 1.9 79.8 11.9 0.2 5.0 1.1 226.5 32.9 17.1 140.8 4.4 24.8 1.8 10.2 0.3 13.7 3.4 3.0 3.6 PTPN20 "bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B" ENSG00000204179 "Protein tyrosine phosphatase non-receptor type 20" Q4JDL3 10 46911396-47002488 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16.3;Distal tubular cells: 21.5;Early spermatids: 44.2;Late spermatids: 34.9;Proximal tubular cells: 17.7;Spermatocytes: 24.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HDLM-2: 50.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043337, HPA046896, HPA048310, HPA069148" Enhanced Supported "Centriolar satellite" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Centriolar satellite" "HPA043337: AB_2678436, HPA046896: , HPA048310: AB_2680350, HPA069148: " "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.04e-2)" "unprognostic (2.82e-3)" "unprognostic (6.78e-2)" "unprognostic (1.85e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (1.53e-1)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-2)" "unprognostic (1.75e-1)" "unprognostic (8.34e-2)" 1.6 9.1 3.4 0.2 4.4 0.2 3.5 9.2 5.1 0.8 8.9 0.9 1.3 0.9 0.3 3.4 1.4 0.7 9.1 3.9 5.2 4.4 0.8 0.8 0.4 18.5 9.0 1.9 4.1 0.0 3.1 0.2 19.6 1.2 1.6 2.9 2.4 1.4 12.3 5.7 0.6 0.8 4.6 1.2 1.1 14.0 5.3 0.3 2.0 14.7 0.6 0.9 1.1 4.8 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 2.9 0.0 3.7 0.0 0.0 0.0 50.2 0.1 0.1 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 2.2 1.3 9.0 5.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.9 7.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.1 0.3 0.1 0.6 0.9 0.0 0.8 0.0 0.7 0.4 0.2 3.4 4.4 9.2 5.1 3.9 5.2 18.5 9.0 19.6 4.6 5.3 4.8 0.5 0.0 1.5 0.0 0.7 0.0 2.0 0.0 5.7 6.0 5.9 3.7 16.3 0.0 2.5 9.2 6.2 0.1 0.3 0.7 21.5 1.8 44.2 5.0 0.1 0.5 1.2 1.7 0.0 0.9 0.2 1.9 3.1 0.2 0.0 4.9 1.4 0.9 0.4 11.8 0.0 0.4 0.0 0.0 0.0 34.9 0.0 0.4 0.0 0.0 0.7 7.3 0.0 0.0 0.0 2.2 0.2 7.2 1.5 0.9 0.2 17.7 3.6 3.1 0.0 2.7 0.8 24.8 12.2 5.2 0.0 0.1 0.4 8.4 0.8 0.9 PXDNL "FLJ25471, PMR1" ENSG00000147485 "Peroxidasin like" A1KZ92 8 51319577-51809445 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Endonuclease, Hydrolase, Nuclease, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 45.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 42.2;Early spermatids: 43.8;Excitatory neurons: 25.2;Inhibitory neurons: 68.8;Microglial cells: 16.9;Muller glia cells: 18.6;Spermatocytes: 24.2" "Group enriched" "Detected in some" 4 "breast cancer: 1.7;glioma: 0.7;renal cancer: 0.8;testis cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 7.7;Daudi: 5.9;SH-SY5Y: 6.1" HPA007919 Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA007919: AB_1855966" "prognostic unfavorable (3.27e-5)" "unprognostic (4.59e-4)" "unprognostic (5.57e-3)" "unprognostic (2.83e-3)" "unprognostic (2.71e-1)" "unprognostic (5.14e-2)" "unprognostic (1.18e-1)" "unprognostic (7.18e-3)" "unprognostic (1.85e-1)" "unprognostic (1.15e-1)" "unprognostic (7.07e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-4)" "unprognostic (2.28e-2)" "unprognostic (3.35e-2)" "unprognostic (2.42e-2)" "unprognostic (2.97e-4)" 1.6 0.1 0.2 0.2 0.1 0.0 0.2 0.2 0.6 0.1 0.0 0.1 0.0 0.1 9.4 0.2 0.0 0.1 45.3 0.2 0.3 1.6 0.0 0.2 0.3 0.5 0.6 0.1 0.0 0.2 0.0 0.0 0.8 0.2 0.1 2.9 0.3 0.0 1.4 0.2 0.2 0.0 0.1 0.4 0.0 5.0 0.2 0.5 0.3 2.1 0.5 0.0 0.0 0.4 0.5 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.2 0.3 0.5 0.6 0.8 0.1 0.2 0.4 0.3 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 1.2 3.7 0.1 42.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.9 0.0 43.8 0.0 0.0 0.3 0.0 0.0 25.2 0.0 0.0 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 68.8 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 16.9 0.0 18.6 0.0 14.1 14.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.2 0.8 24.2 1.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.8;Distal enterocytes: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 407.8;SK-MEL-30: 528.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 14000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031067: AB_2673722" "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.37e-4)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.43e-4)" 50.8 36.4 78.2 27.7 77.9 14.1 61.1 84.1 82.4 37.0 35.4 140.9 27.0 51.9 21.4 106.6 37.8 39.1 163.9 77.3 74.9 43.7 14.6 32.1 19.1 85.4 80.8 25.9 25.4 18.1 61.5 11.5 81.2 107.9 72.6 25.4 125.1 106.3 18.7 85.3 44.8 59.8 84.7 22.6 51.3 25.2 80.3 18.4 45.2 10.5 17.3 154.2 53.0 84.8 31.5 220.1 39.1 38.3 97.9 182.7 28.7 62.2 80.9 51.4 43.0 50.1 38.0 37.1 71.8 83.6 96.1 123.9 44.5 165.8 27.9 21.1 27.5 29.5 18.6 86.9 115.7 44.7 40.0 107.1 152.4 130.5 191.3 63.5 66.6 23.0 16.5 91.4 73.0 87.1 45.1 34.6 35.2 38.2 407.8 33.7 71.0 49.8 280.5 56.8 58.4 36.5 42.7 74.0 528.7 31.0 51.9 28.4 147.4 60.3 36.5 65.1 128.7 35.2 58.8 14.4 67.9 34.8 335.3 4.6 14.1 7.1 10.2 19.4 9.9 5.4 8.1 9.2 14.5 4.6 10.3 12.9 3.3 11.2 23.4 7.1 9.6 23.4 78.2 77.9 84.1 82.4 77.3 74.9 85.4 80.8 81.2 84.7 80.3 84.8 10.0 9.6 34.6 43.1 8.7 11.9 23.1 20.7 22.2 35.8 31.6 43.6 122.8 11.5 14.6 25.8 37.5 7.1 10.7 185.2 11.7 17.6 3.5 12.7 17.2 13.5 28.2 8.6 22.9 16.5 7.2 15.3 40.2 21.6 6.3 16.2 8.9 5.8 10.8 18.5 26.9 47.3 57.0 13.8 10.7 9.2 27.4 18.5 35.6 15.0 16.6 21.3 15.5 11.6 19.1 27.0 68.5 86.5 22.9 17.6 20.9 11.1 11.9 9.3 0.0 13.5 23.1 2.0 8.5 15.3 10.1 4.4 12.9 20.3 72.0 9.7 QARS1 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase 1" P47897 3 49095932-49105130 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 55.5;Cytotrophoblasts: 193.9;Extravillous trophoblasts: 156.7;Hofbauer cells: 96.1;Syncytiotrophoblasts: 187.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol No No 58000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA036986: AB_10672344, HPA036987: AB_2675418" "prognostic favorable (1.43e-4)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (1.10e-2)" "unprognostic (5.13e-3)" "unprognostic (6.62e-3)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.51e-1)" "unprognostic (4.33e-1)" "unprognostic (9.14e-2)" "prognostic favorable (5.60e-6)" "unprognostic (2.73e-3)" "unprognostic (1.65e-1)" "unprognostic (2.74e-2)" "unprognostic (3.11e-1)" 61.1 58.8 20.0 57.2 21.3 96.6 89.5 23.5 18.5 58.3 34.2 104.8 101.6 45.5 58.5 102.5 71.0 48.3 72.0 18.4 21.1 57.1 51.1 52.3 75.8 23.8 21.0 69.0 73.9 78.1 33.0 76.7 23.0 60.4 121.0 21.4 103.2 61.1 156.1 105.0 84.6 60.2 22.7 60.1 75.0 30.0 23.0 92.3 53.2 146.2 118.8 72.8 58.1 24.6 95.9 97.8 128.0 197.4 146.4 180.8 159.2 90.5 188.2 160.5 152.9 123.0 113.5 257.1 61.4 136.7 95.3 119.9 166.3 137.8 111.4 78.2 148.0 206.4 156.0 216.1 91.2 187.2 130.9 184.8 123.1 127.4 108.1 175.3 184.7 144.6 95.3 112.4 118.0 89.2 130.7 154.9 116.1 159.0 122.9 76.0 123.7 200.6 108.5 163.9 48.7 161.6 85.4 211.0 147.8 122.7 184.4 205.5 137.6 82.8 127.3 131.7 117.9 111.9 176.5 142.9 88.4 156.3 60.3 30.7 84.3 25.8 44.5 104.1 57.4 62.2 54.1 47.0 127.0 49.9 46.6 49.0 8.0 71.8 94.5 57.4 82.1 81.2 20.0 21.3 23.5 18.5 18.4 21.1 23.8 21.0 23.0 22.7 23.0 24.6 15.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 0.0 0.0 0.0 0.0 193.9 11.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 156.7 14.7 0.0 0.0 0.0 0.0 0.0 0.0 96.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 187.0 2.0 0.0 0.0 0.0 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;testis: 48.8" "Cell type enhanced" "Detected in many" "Early spermatids: 334.6;Horizontal cells: 212.0;Late spermatids: 1251.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.7" "Cell line enhanced" "Detected in many" "BEWO: 64.3;Daudi: 36.8;Hep G2: 40.6;HMC-1: 41.5;RT4: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA063203: AB_2684962" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "prognostic favorable (2.70e-4)" "unprognostic (6.03e-3)" "unprognostic (4.29e-2)" "unprognostic (4.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.74e-8)" "prognostic favorable (1.22e-4)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" 0.9 1.1 68.9 8.1 72.0 15.0 4.1 48.9 71.4 2.7 22.0 9.3 12.9 1.2 11.2 6.7 7.5 3.2 2.7 66.2 47.6 6.8 2.9 5.7 11.8 55.3 66.0 2.4 17.6 6.1 3.5 10.5 51.7 2.5 7.3 7.7 7.4 3.8 0.5 8.1 14.7 0.9 54.3 7.4 13.4 48.8 70.7 4.6 4.6 0.4 10.7 5.1 2.1 78.4 12.4 1.4 1.3 3.2 0.5 0.0 64.3 0.2 0.0 0.8 0.8 20.7 1.9 36.8 4.6 0.2 13.3 10.3 12.2 5.9 0.5 7.5 11.0 0.0 0.5 40.6 0.3 2.7 41.5 0.3 5.9 0.8 2.6 0.4 0.0 10.9 2.7 0.9 0.0 9.8 2.7 0.7 10.5 22.9 0.4 1.0 0.1 7.1 2.3 37.8 19.1 13.9 2.8 17.4 14.6 8.7 25.7 1.2 0.0 0.7 6.3 0.1 0.6 6.6 5.6 3.4 0.2 3.7 2.5 5.5 8.4 78.7 13.9 11.9 8.7 5.8 7.2 10.3 5.4 8.6 7.6 9.1 40.5 6.4 15.8 1.1 9.6 8.7 68.9 72.0 48.9 71.4 66.2 47.6 55.3 66.0 51.7 54.3 70.7 78.4 0.6 6.4 8.3 15.7 12.1 3.1 11.4 5.7 1.8 9.6 9.1 5.2 7.3 15.7 9.6 11.0 10.4 73.1 19.8 32.6 13.7 17.5 334.6 39.0 3.9 1.5 14.9 2.7 68.6 28.2 10.9 2.3 17.3 48.8 12.0 7.3 1.1 4.4 6.0 212.0 71.0 16.0 12.2 1.9 5.7 1251.4 5.3 6.3 10.6 1.9 11.1 53.7 26.8 13.6 72.3 24.8 20.2 4.9 7.0 11.1 25.9 12.4 18.1 7.4 0.0 3.1 2.7 8.3 9.7 4.4 3.0 50.3 15.2 0.2 21.1 15.4 RAB3A ENSG00000105649 "RAB3A, member RAS oncogene family" P20336 19 18196784-18204042 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 290.7;retina: 77.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.4;Distal tubular cells: 39.2;Excitatory neurons: 34.0;Horizontal cells: 92.5;Inhibitory neurons: 41.0;Rod photoreceptor cells: 46.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 290.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 20.8;SCLC-21H: 37.5;SH-SY5Y: 18.0;U-2197: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, CAB009949, CAB078998" Enhanced Supported Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Centrosome, Cytosol" "CAB009949: AB_632292, CAB078998: , HPA003160: AB_1079731" "unprognostic (1.82e-1)" "unprognostic (2.22e-1)" "unprognostic (6.80e-3)" "prognostic unfavorable (3.17e-4)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (1.36e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.64e-1)" "unprognostic (4.46e-3)" "unprognostic (1.13e-1)" "prognostic favorable (6.14e-7)" "unprognostic (1.23e-1)" "unprognostic (1.88e-1)" "unprognostic (1.85e-2)" "unprognostic (6.14e-2)" 2.6 15.6 41.0 1.7 56.7 0.9 2.1 6.8 290.7 3.3 0.0 6.4 3.1 2.7 1.5 2.5 5.2 2.0 25.7 53.4 32.5 5.9 3.8 2.5 1.5 26.8 4.6 25.8 2.0 12.8 38.4 1.4 23.3 3.9 1.8 77.5 4.0 3.9 9.9 4.1 3.2 2.1 0.0 2.8 4.5 2.2 29.4 1.3 2.3 8.9 0.9 2.6 3.6 90.5 1.4 1.6 3.5 4.9 5.7 1.4 2.2 3.2 1.9 2.2 2.9 1.4 0.9 5.2 3.4 2.6 2.0 4.2 16.6 2.0 1.0 1.1 5.3 2.1 6.3 6.0 1.4 3.6 6.2 4.6 2.0 1.2 0.6 4.2 0.6 6.4 1.1 1.8 2.0 5.2 8.0 1.0 2.9 4.4 20.8 5.5 0.3 4.4 2.3 0.8 37.5 18.0 1.6 6.6 3.7 1.4 1.4 0.6 0.7 1.8 1.4 26.2 1.8 3.2 7.4 1.3 4.9 2.7 1.7 0.0 1.3 1.8 1.3 0.9 1.8 1.9 1.3 1.3 2.9 0.9 1.7 1.8 2.2 0.3 1.3 2.6 0.8 1.3 41.0 56.7 6.8 290.7 53.4 32.5 26.8 4.6 23.3 0.0 29.4 90.5 2.3 0.0 0.0 8.5 4.7 3.2 2.5 3.7 8.6 102.4 4.8 4.8 1.3 2.8 2.2 16.5 8.4 1.6 7.4 1.6 39.2 2.3 2.4 1.0 1.3 2.6 9.6 0.0 34.0 0.9 5.2 3.1 2.0 1.4 0.0 1.6 2.5 1.6 5.2 92.5 41.0 2.8 4.1 2.2 15.3 0.2 4.4 4.5 10.6 13.1 2.9 15.4 1.0 7.5 10.1 1.0 2.0 5.7 1.1 1.1 5.3 8.3 1.2 46.5 0.0 1.8 8.2 0.4 3.6 6.0 4.8 1.8 5.3 4.5 4.2 2.1 RAB9B RAB9L ENSG00000123570 "RAB9B, member RAS oncogene family" Q9NP90 X 103822327-103832257 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 21.3;Cardiomyocytes: 79.0;Excitatory neurons: 28.4;Inhibitory neurons: 18.7;Muller glia cells: 32.2;Oligodendrocyte precursor cells: 37.7;Peritubular cells: 30.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 4.5;MOLT-4: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061932 Approved "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA061932: AB_2684640" "unprognostic (1.69e-2)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (7.28e-5)" "unprognostic (5.81e-2)" "unprognostic (3.89e-2)" "unprognostic (8.40e-2)" "unprognostic (1.42e-2)" "unprognostic (8.34e-2)" "unprognostic (8.29e-2)" "unprognostic (3.52e-4)" "unprognostic (1.10e-1)" "unprognostic (9.21e-4)" "unprognostic (1.37e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" 1.8 2.8 6.4 0.9 6.6 0.1 1.3 8.1 7.2 3.0 0.0 6.5 1.0 5.0 2.4 8.3 6.8 2.4 21.5 6.2 8.8 0.4 0.1 0.7 0.6 4.0 3.6 7.2 1.0 3.9 5.1 0.2 6.8 7.1 2.2 5.2 1.1 9.5 9.4 0.5 1.7 9.8 3.7 0.5 2.2 1.8 8.8 1.5 1.4 5.6 0.4 7.0 1.6 4.7 0.0 0.0 2.9 1.5 0.8 0.1 0.1 0.7 1.8 1.8 1.7 0.2 0.0 0.1 1.7 1.5 1.1 0.0 0.5 0.1 1.6 0.1 1.9 0.1 0.0 0.0 0.2 0.2 0.1 0.4 0.0 0.8 0.0 1.8 0.1 4.5 0.0 1.1 0.1 1.3 3.7 0.0 0.5 0.0 0.5 3.2 3.3 0.1 1.0 0.3 3.0 2.1 0.2 0.1 0.6 0.5 0.3 0.2 0.1 0.1 0.5 1.0 0.6 0.1 0.0 0.2 1.6 0.2 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.8 0.0 0.1 0.1 0.0 6.4 6.6 8.1 7.2 6.2 8.8 4.0 3.6 6.8 3.7 8.8 4.7 1.0 0.0 2.4 8.5 0.7 0.4 0.7 0.1 0.6 21.3 1.6 1.9 79.0 0.0 0.7 0.0 0.0 0.4 0.2 0.5 0.0 0.5 0.0 0.3 0.7 2.4 7.7 1.3 28.4 1.0 0.3 4.1 0.0 0.2 4.5 2.8 0.7 0.0 0.3 0.0 18.7 0.7 0.0 0.0 0.4 0.9 6.5 0.2 0.0 1.9 0.0 32.2 2.1 37.7 6.2 1.0 2.5 30.1 0.1 0.2 0.1 0.2 0.8 3.6 6.6 2.3 5.0 0.8 0.9 0.5 0.3 0.0 0.2 4.7 0.6 0.2 RABGAP1L "FLJ38519, HHL, KIAA0471, TBC1D18" ENSG00000152061 "RAB GTPase activating protein 1 like" "B7ZAP0, Q5R372" 1 174159410-174995308 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 121.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 551.4;Inhibitory neurons: 444.0;Microglial cells: 267.0;Oligodendrocyte precursor cells: 362.4;Oligodendrocytes: 342.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 136.9;Karpas-707: 87.6;U-698: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054695 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054695: AB_2682577" "unprognostic (2.57e-2)" "unprognostic (7.77e-2)" "unprognostic (6.78e-2)" "unprognostic (6.89e-3)" "unprognostic (1.54e-2)" "unprognostic (6.96e-3)" "unprognostic (8.55e-2)" "prognostic favorable (1.16e-4)" "unprognostic (2.66e-2)" "unprognostic (3.51e-2)" "unprognostic (2.66e-2)" "unprognostic (1.98e-1)" "unprognostic (9.14e-3)" "unprognostic (6.69e-2)" "unprognostic (2.14e-1)" "unprognostic (5.03e-2)" "unprognostic (2.46e-1)" 12.1 8.6 16.1 22.8 19.1 31.1 15.7 46.1 20.6 15.0 51.2 20.4 22.0 13.1 16.3 18.6 19.0 22.1 121.0 19.4 17.2 16.8 16.3 26.4 41.9 9.6 13.2 28.8 19.9 10.5 20.5 18.3 11.2 10.4 21.2 16.2 23.6 10.5 6.5 16.5 24.3 13.4 10.0 26.3 22.6 31.1 15.9 20.1 10.0 7.4 50.1 19.9 10.3 19.5 15.6 8.0 6.0 6.2 16.4 23.9 13.3 18.1 16.0 7.9 10.6 7.5 56.0 136.9 12.5 14.0 9.3 19.6 5.2 12.1 11.0 37.7 8.5 34.2 11.0 11.5 10.1 15.1 13.2 18.9 8.2 5.7 8.5 13.3 17.7 12.6 20.2 87.6 12.8 5.3 11.9 14.4 37.2 20.9 4.8 41.0 12.0 45.7 15.5 70.9 17.5 10.4 17.2 28.8 12.1 18.4 14.0 18.1 24.5 9.9 8.9 11.0 10.7 75.6 26.3 85.7 10.9 10.1 7.5 16.7 50.0 110.2 25.7 86.5 22.7 34.7 31.5 31.5 40.3 26.4 15.2 23.5 89.6 80.3 180.8 53.6 42.3 32.9 16.1 19.1 46.1 20.6 19.4 17.2 9.6 13.2 11.2 10.0 15.9 19.5 23.1 73.7 106.1 143.7 63.8 12.4 11.4 19.9 39.3 38.7 20.7 13.2 263.0 47.1 38.6 33.1 31.3 39.1 101.2 43.3 13.7 28.8 117.2 59.0 18.6 17.6 49.1 33.8 551.4 36.9 9.5 35.3 46.9 46.8 24.6 8.9 23.9 16.3 38.5 21.9 444.0 37.8 18.3 57.0 16.2 121.3 15.5 63.1 16.0 267.0 100.4 17.3 68.0 362.4 342.8 24.5 36.0 18.8 81.8 11.5 39.8 13.3 100.3 23.8 6.6 15.0 25.1 91.8 18.5 36.9 13.1 28.2 74.6 26.1 27.0 27.5 RALGPS1 "KIAA0351, RALGEF2, RALGPS1A" ENSG00000136828 "Ral GEF with PH domain and SH3 binding motif 1" Q5JS13 9 126914774-127223166 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 87.8;Cone photoreceptor cells: 104.3;Excitatory neurons: 105.6;Inhibitory neurons: 164.4;Oligodendrocytes: 161.3;Rod photoreceptor cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014749 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA014749: " "unprognostic (3.49e-2)" "unprognostic (3.35e-2)" "unprognostic (4.14e-2)" "unprognostic (2.06e-1)" "unprognostic (2.00e-1)" "unprognostic (5.10e-2)" "unprognostic (1.09e-1)" "unprognostic (6.69e-3)" "unprognostic (3.47e-1)" "unprognostic (4.68e-2)" "unprognostic (5.02e-3)" "unprognostic (3.49e-1)" "prognostic favorable (6.20e-11)" "unprognostic (4.79e-2)" "unprognostic (7.68e-2)" "unprognostic (3.75e-2)" "unprognostic (3.24e-3)" 3.7 3.4 15.3 3.7 13.8 3.2 6.6 18.8 16.3 5.4 5.9 12.5 30.6 4.7 9.3 7.7 8.5 6.4 13.0 13.4 14.7 14.6 2.7 6.5 4.4 18.7 13.8 4.1 11.3 15.9 18.8 3.9 20.2 7.9 13.0 30.7 13.1 8.2 9.4 10.0 29.1 4.5 13.6 5.2 18.2 10.6 16.4 4.8 13.8 6.0 6.4 8.5 5.9 22.0 3.5 3.1 8.1 8.0 1.5 1.1 8.8 1.1 1.1 1.7 2.4 8.6 5.8 5.8 0.8 1.4 10.3 12.0 2.5 1.4 1.0 2.3 4.9 0.4 4.3 1.5 1.2 1.0 6.3 0.7 4.9 0.8 1.0 1.4 2.8 13.3 0.8 5.8 0.4 6.5 1.1 0.9 2.2 33.6 2.7 3.9 1.9 11.2 3.4 8.6 7.4 11.1 3.4 10.5 2.5 5.6 9.5 0.5 1.3 0.7 2.4 1.6 1.3 10.5 10.8 3.0 3.2 1.0 1.2 0.0 0.1 0.7 0.1 0.0 0.2 2.3 0.3 0.2 0.0 0.7 0.1 0.1 0.9 0.8 0.1 0.7 0.1 0.1 15.3 13.8 18.8 16.3 13.4 14.7 18.7 13.8 20.2 13.6 16.4 22.0 6.2 6.4 4.1 87.8 11.2 2.7 4.4 3.6 2.2 36.8 8.5 5.1 10.2 17.2 10.2 11.0 104.3 9.6 3.6 18.8 5.9 6.1 27.6 11.8 2.6 2.3 7.8 0.0 105.6 6.4 1.0 3.2 34.7 7.2 0.0 6.5 3.3 2.1 2.6 45.4 164.4 16.8 12.2 2.5 2.8 41.4 1.5 2.7 1.8 31.9 3.5 12.4 8.2 68.3 161.3 8.9 14.7 3.8 5.5 6.2 56.9 3.9 13.4 119.0 6.6 5.8 3.2 31.3 12.3 11.6 4.7 4.0 4.7 4.4 17.8 9.1 RALYL HNRPCL3 ENSG00000184672 "RALY RNA binding protein like" Q86SE5 8 84182787-84921844 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 19.8;brain: 68.1;kidney: 19.2" "Cell type enriched" "Detected in some" 5 "Excitatory neurons: 2828.9" "Cancer enhanced" "Detected in single" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 31.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055868, HPA059112" Enhanced Enhanced Nucleoplasm NA NA "Cluster 6: Brain - Smell perception" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA055868: AB_2682950, HPA059112: AB_2683908" "unprognostic (1.13e-5)" "unprognostic (1.62e-1)" "unprognostic (7.48e-2)" "unprognostic (1.36e-1)" "unprognostic (5.04e-2)" "unprognostic (1.25e-2)" "unprognostic (1.74e-1)" "unprognostic (4.82e-5)" "unprognostic (2.74e-2)" "unprognostic (2.52e-1)" 0.1 19.8 31.9 0.2 35.2 0.2 0.1 68.1 40.2 0.0 0.0 0.7 0.3 0.1 0.7 0.0 0.6 5.0 2.3 27.0 27.5 19.2 0.3 0.1 0.1 12.3 17.3 0.0 2.3 0.0 6.1 1.2 22.7 0.2 0.4 9.0 0.6 2.0 0.2 0.2 0.6 0.1 7.6 2.4 0.5 0.4 26.5 0.0 0.1 0.3 0.1 0.1 0.1 28.5 0.1 0.0 4.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 31.5 0.2 0.0 0.4 0.0 0.0 0.0 0.7 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.4 0.2 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 35.2 68.1 40.2 27.0 27.5 12.3 17.3 22.7 7.6 26.5 28.5 0.0 0.0 0.0 50.6 0.0 0.0 0.0 0.0 0.0 38.5 1.0 0.6 5.0 21.5 0.0 7.3 2.1 0.0 0.0 0.0 178.1 1.0 2.2 0.0 0.0 0.9 1.8 0.0 2828.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 33.7 531.4 0.6 0.0 0.0 0.0 1.5 0.3 0.0 0.0 68.4 0.0 32.8 0.0 495.6 36.3 0.1 0.0 0.0 0.0 0.0 11.7 19.4 0.0 5.2 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 4.0 0.1 0.1 RAP1GAP2 "GARNL4, KIAA1039" ENSG00000132359 "RAP1 GTPase activating protein 2" Q684P5 17 2755705-3037741 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.7;pancreas: 37.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 132.8;Inhibitory neurons: 67.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 12 "amygdala: 10.6;basal ganglia: 13.6;cerebral cortex: 11.0;hippocampal formation: 17.9;white matter: 11.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022148, HPA022896" Approved Supported "Nuclear membrane,Cytosol" NA NA 21000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Cytosol" "HPA022148: AB_1849474, HPA022896: AB_1849476" "unprognostic (1.85e-3)" "unprognostic (1.02e-2)" "unprognostic (8.92e-2)" "unprognostic (5.39e-1)" "unprognostic (4.04e-2)" "unprognostic (3.92e-1)" "unprognostic (6.52e-5)" "unprognostic (1.18e-2)" "unprognostic (2.91e-1)" "unprognostic (2.22e-1)" "unprognostic (1.66e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.36e-6)" "unprognostic (3.44e-2)" "unprognostic (6.38e-2)" "unprognostic (9.33e-2)" "unprognostic (7.50e-2)" 1.8 6.4 10.6 4.1 13.6 27.7 4.4 0.9 11.0 3.9 0.0 7.9 8.7 4.1 1.1 3.1 8.1 4.0 14.5 17.9 1.1 5.2 0.6 3.5 2.9 0.0 0.0 4.6 37.3 4.2 5.1 4.9 0.0 3.8 8.1 7.2 10.9 4.7 0.8 3.3 8.2 3.3 0.0 3.9 22.4 3.2 0.0 2.8 2.5 2.0 2.5 2.0 2.5 11.9 8.1 9.9 1.9 8.1 0.0 0.0 15.9 10.7 5.0 1.3 1.2 21.9 3.5 3.0 2.9 1.4 13.5 11.0 6.4 20.0 0.4 0.0 6.9 3.7 14.1 9.9 1.9 0.8 3.9 0.5 17.0 5.5 13.9 7.2 0.2 3.7 21.4 1.4 0.0 9.1 3.1 2.0 11.7 3.9 9.5 13.4 6.9 7.8 5.9 4.1 21.6 52.3 15.5 15.8 6.9 7.4 7.8 2.3 2.4 9.1 14.3 1.6 9.1 0.0 0.0 1.2 0.5 6.9 15.1 0.9 1.4 2.1 2.8 2.7 1.1 0.2 0.9 2.1 1.0 0.2 0.1 1.0 4.2 1.9 3.9 1.7 1.0 1.4 10.6 13.6 0.9 11.0 17.9 1.1 0.0 0.0 0.0 0.0 0.0 11.9 1.5 6.4 2.5 13.7 5.6 2.0 6.6 1.8 1.2 23.6 9.9 7.6 20.2 11.5 2.8 12.9 33.3 7.5 27.2 15.2 9.8 6.0 6.1 9.2 6.8 1.6 48.1 0.8 132.8 12.0 6.0 2.2 18.8 9.2 6.3 3.0 3.6 0.8 3.4 37.0 67.9 21.7 8.2 11.1 4.3 8.3 1.8 11.0 3.6 47.8 12.0 2.1 35.0 8.0 4.2 12.4 24.1 1.5 6.4 16.5 5.7 0.8 4.2 4.6 0.0 7.9 2.5 0.4 3.4 2.8 0.4 3.4 8.2 1.5 14.0 11.3 RAPSN "CMS1D, CMS1E, RNF205" ENSG00000165917 "Receptor associated protein of the synapse" Q13702 11 47437764-47449143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 88.9;tongue: 33.1" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 63.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 238.7" "Low region specificity" "Detected in some" HPA039475 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Centrosome, Cytosol" "HPA039475: AB_10794196" "unprognostic (5.37e-2)" "unprognostic (1.02e-1)" "unprognostic (7.34e-2)" "unprognostic (4.58e-2)" "unprognostic (2.95e-2)" "unprognostic (1.44e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-3)" "unprognostic (1.35e-1)" "unprognostic (5.38e-2)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.64e-4)" "unprognostic (3.83e-1)" "unprognostic (4.73e-3)" "unprognostic (4.48e-2)" 0.3 1.5 0.5 0.2 0.5 0.3 0.2 0.3 1.2 0.2 0.9 0.8 0.1 0.0 0.1 1.2 0.1 0.1 2.6 0.5 0.5 0.3 0.5 0.4 0.2 0.3 0.5 0.0 0.2 0.0 0.1 2.1 0.5 0.7 0.0 0.1 1.3 0.0 88.9 0.5 0.5 0.1 0.4 0.6 0.2 0.3 0.6 0.1 0.2 33.1 0.1 0.1 0.1 0.5 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.7 0.1 0.2 1.2 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 59.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 238.7 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.3 0.1 0.3 0.3 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 1.2 0.5 0.5 0.3 0.5 0.5 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.3 1.4 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.5 2.7 0.3 0.1 0.2 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.5 0.0 0.2 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.3 0.3 13.8 0.0 0.5 0.0 0.0 0.6 1.3 0.0 0.5 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 1.1 0.0 0.0 63.8 0.5 0.0 0.4 0.0 0.0 0.3 0.4 0.1 0.2 0.1 RBFOX1 "A2BP1, FOX-1, HRNBP1" ENSG00000078328 "RNA binding fox-1 homolog 1" Q9NWB1 16 5239802-7713340 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 73.9;heart muscle: 25.2;skeletal muscle: 95.3;tongue: 45.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 5800.8;Inhibitory neurons: 5921.8" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Group enriched" "Detected in many" 10 "basal ganglia: 28.1;cerebral cortex: 73.9;hippocampal formation: 26.6;white matter: 22.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "RH-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040809, HPA066746, HPA075862" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" No No "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA040809: AB_10796228, HPA066746: , HPA075862: " "unprognostic (3.75e-3)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-2)" "unprognostic (5.19e-3)" "unprognostic (8.82e-5)" "unprognostic (5.02e-1)" "unprognostic (3.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.43e-2)" "unprognostic (3.24e-2)" "unprognostic (2.23e-1)" "unprognostic (5.00e-2)" "unprognostic (2.28e-1)" 0.3 1.5 3.7 0.4 28.1 0.5 0.1 2.5 73.9 0.6 0.0 0.8 0.2 0.2 3.1 1.1 1.1 0.1 25.2 26.6 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.0 1.1 0.1 0.0 1.7 0.5 5.7 2.2 4.1 95.3 0.3 0.2 0.0 2.7 0.0 0.2 1.1 2.2 0.2 0.1 45.3 0.0 0.4 0.4 22.6 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.7 0.0 0.0 0.1 1.6 0.0 0.0 0.0 25.9 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.2 0.0 0.2 0.2 0.3 0.0 0.7 0.1 0.4 0.2 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.3 0.2 0.7 0.2 0.1 0.1 0.2 0.0 3.7 28.1 2.5 73.9 26.6 0.0 0.0 0.0 0.0 2.7 2.2 22.6 0.0 0.0 0.5 97.9 0.0 0.0 0.0 0.0 0.0 10.9 0.4 0.0 98.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 6.6 0.3 1.8 0.9 0.0 0.0 5800.8 0.2 0.0 3.5 0.0 0.1 0.0 47.8 0.0 0.0 0.1 0.0 5921.8 0.5 0.0 0.0 0.3 4.9 1.2 0.5 1.8 132.1 0.6 6.6 0.0 597.6 689.4 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.7 2.8 0.0 17.0 1.2 0.6 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 209.7;Urothelial cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 60.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" 4.5 4.8 2.5 3.4 2.6 2.2 4.5 3.9 3.6 9.4 3.9 8.6 6.7 4.2 0.7 19.8 4.8 3.0 13.0 2.4 3.5 9.2 8.2 4.4 3.5 3.5 4.2 3.7 8.6 12.4 6.4 10.1 3.7 6.3 3.8 2.1 9.6 3.7 9.7 21.0 6.1 2.0 1.6 6.2 10.5 5.3 3.8 2.2 7.5 4.8 2.7 5.1 12.2 2.3 10.9 12.3 2.9 10.3 1.5 3.0 17.9 3.4 2.1 3.7 6.4 23.3 15.7 9.4 5.3 1.2 2.7 14.1 7.8 7.2 1.7 7.3 60.0 12.2 9.8 14.6 2.9 12.4 8.0 2.6 6.3 3.0 2.9 3.7 3.0 5.2 27.2 2.9 2.3 13.4 6.1 9.6 2.5 17.7 25.7 15.7 6.7 27.6 8.2 37.3 8.8 6.2 8.9 31.3 7.0 2.7 12.0 9.3 3.0 0.3 3.7 0.1 8.2 7.8 11.0 9.6 9.1 10.6 6.6 3.8 4.1 4.1 8.2 6.3 7.7 5.4 6.3 7.6 4.2 5.8 8.4 6.1 1.9 7.8 5.0 6.4 5.5 3.0 2.5 2.6 3.9 3.6 2.4 3.5 3.5 4.2 3.7 1.6 3.8 2.3 8.9 16.0 13.1 3.9 6.6 10.7 31.7 11.1 7.4 21.0 12.2 9.9 27.5 20.0 19.3 14.7 41.7 41.3 9.4 47.2 11.7 13.5 24.3 18.3 8.8 9.1 12.0 4.2 9.4 6.5 29.0 7.1 46.4 31.8 8.2 24.4 18.5 7.3 11.5 25.2 10.0 27.5 12.2 4.9 5.0 13.2 3.7 4.2 7.2 4.7 5.0 9.0 6.2 5.0 2.9 14.5 35.7 3.4 8.7 30.6 20.3 4.8 12.8 25.3 6.6 5.1 6.5 3.2 8.9 11.1 17.5 209.7 9.2 11.1 28.1 110.1 REPIN1 "AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464" ENSG00000214022 "Replication initiator 1" Q9BWE0 7 150368189-150374044 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 7.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 246.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036022 Approved Supported Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA036022: AB_10610417" "unprognostic (2.73e-1)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "unprognostic (7.50e-3)" "unprognostic (5.42e-2)" "unprognostic (7.00e-3)" "unprognostic (1.52e-2)" "unprognostic (6.88e-3)" "unprognostic (6.68e-2)" "unprognostic (6.59e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.40e-2)" "prognostic favorable (5.56e-4)" "prognostic favorable (1.61e-4)" "unprognostic (1.79e-1)" "unprognostic (2.02e-3)" "prognostic favorable (6.41e-4)" 28.7 77.2 45.1 25.2 43.6 44.1 35.1 43.1 46.4 31.7 54.6 68.4 42.2 37.5 31.8 37.4 40.9 14.6 65.3 37.9 40.0 51.5 86.6 31.7 35.7 52.3 46.7 37.3 67.7 35.5 69.7 12.1 45.5 49.2 28.3 23.7 41.7 23.9 134.5 31.8 56.5 15.4 41.1 56.2 53.1 18.2 49.5 41.0 45.0 66.2 24.8 42.5 25.0 42.1 59.4 71.3 66.1 81.5 15.8 11.3 40.2 28.7 35.2 27.6 23.8 55.5 37.6 65.5 70.9 20.6 48.0 43.4 36.4 11.4 13.9 72.0 54.8 38.4 40.3 70.4 52.3 68.4 60.1 14.7 34.1 15.2 3.5 26.1 39.4 39.1 93.5 39.9 23.1 76.7 95.1 77.4 69.5 39.7 69.9 51.8 76.4 246.3 29.4 103.7 96.9 123.7 43.3 107.5 75.8 27.2 52.8 54.2 42.1 21.2 17.4 23.6 58.7 115.4 46.1 59.8 37.1 59.9 53.3 0.0 1.4 2.7 0.8 0.7 1.3 2.5 1.8 1.5 2.2 2.4 2.3 1.1 1.4 1.8 0.3 7.8 0.8 0.9 45.1 43.6 43.1 46.4 37.9 40.0 52.3 46.7 45.5 41.1 49.5 42.1 21.1 35.3 18.6 17.9 26.9 9.4 18.3 11.5 14.8 57.9 39.3 33.1 46.5 45.8 15.0 14.7 41.7 28.0 49.5 53.7 62.6 37.3 7.8 53.4 14.3 24.3 68.1 14.5 13.0 50.3 12.9 16.1 23.4 35.8 24.7 56.3 26.0 69.7 32.0 80.8 15.8 68.6 32.6 14.8 23.9 9.8 22.1 21.8 16.0 9.4 88.4 101.3 40.2 17.6 16.6 34.3 37.1 19.9 26.4 31.6 47.0 32.8 36.2 55.8 6.6 28.0 20.1 10.2 3.1 17.6 17.8 25.6 16.0 33.5 109.7 19.9 RETREG1 "FAM134B, FLJ20152, JK1" ENSG00000154153 "Reticulophagy regulator 1" Q9H6L5 5 16473038-16617038 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 91.4;skeletal muscle: 141.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Cytotrophoblasts: 53.7;Exocrine glandular cells: 59.3;Glandular and luminal cells: 197.7;Pancreatic endocrine cells: 51.5;Proximal tubular cells: 152.8" "Cancer enhanced" "Detected in all" "renal cancer: 28.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.3;T-cells: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 26.0;GAMG: 20.3;HSkMC: 28.8;MOLT-4: 20.4;RPTEC TERT1: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012077 Supported "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA012077: AB_2668621" "unprognostic (1.63e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-2)" "unprognostic (9.17e-3)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (4.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "prognostic favorable (5.25e-10)" "unprognostic (3.75e-1)" "unprognostic (9.96e-2)" "unprognostic (5.62e-2)" "unprognostic (2.58e-1)" 15.6 3.5 20.6 6.6 26.4 2.0 13.6 23.9 33.2 13.2 21.6 24.6 12.6 4.0 5.2 3.6 7.5 13.4 91.4 19.4 22.1 61.0 44.2 9.3 6.4 27.2 25.2 2.1 37.7 30.1 9.9 13.2 27.8 11.1 32.4 7.5 5.2 5.0 141.8 10.0 25.6 2.6 23.6 2.3 10.9 12.3 25.0 20.6 6.7 81.9 4.3 2.3 5.2 37.6 1.3 0.5 0.1 3.5 26.0 3.2 15.1 0.1 3.5 3.1 4.1 2.3 0.1 0.3 2.4 0.0 20.3 3.9 7.8 0.8 1.0 4.1 3.4 0.0 10.6 0.0 0.1 5.3 0.0 28.8 11.7 0.6 3.1 7.5 0.0 15.4 0.0 0.1 1.2 1.0 20.4 0.1 0.8 3.4 0.6 3.2 0.0 1.2 26.2 0.9 17.4 2.0 1.0 1.1 13.1 1.9 5.9 2.4 0.0 2.4 0.2 6.4 3.1 0.7 0.0 0.0 14.9 18.0 6.5 2.3 0.1 0.0 0.2 0.0 0.6 0.0 0.6 0.3 0.0 0.3 1.7 1.0 0.9 0.0 0.0 0.0 0.8 0.2 20.6 26.4 23.9 33.2 19.4 22.1 27.2 25.2 27.8 23.6 25.0 37.6 4.2 73.7 8.6 0.0 3.4 0.0 0.0 0.0 0.0 0.0 33.3 19.0 0.0 0.0 9.9 44.1 0.0 53.7 2.2 0.0 17.6 31.1 0.0 33.5 45.2 1.2 0.0 0.0 0.0 59.3 2.0 7.8 0.0 197.7 1.3 3.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.8 0.0 0.0 152.8 19.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 10.9 8.1 0.3 0.0 0.0 RGN "RC, SMP30" ENSG00000130988 Regucalcin Q15493 X 47078355-47093314 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 184.7;liver: 383.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Granulosa cells: 67.8;Hepatocytes: 175.7;Muller glia cells: 54.5;Peritubular cells: 69.6;Proximal tubular cells: 174.4" "Cancer enriched" "Detected in many" 6 "liver cancer: 47.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 21.7;fHDF/TERT166: 6.9;Hep G2: 32.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029102, HPA029103, HPA029104" Enhanced Approved Cytosol NA NA 280000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA029102: AB_10599846, HPA029103: AB_10602097, HPA029104: " "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (5.56e-3)" "unprognostic (8.22e-3)" "unprognostic (1.32e-2)" "prognostic favorable (7.55e-4)" "unprognostic (2.60e-3)" "unprognostic (2.23e-2)" "unprognostic (8.38e-2)" "unprognostic (3.37e-2)" "unprognostic (1.14e-2)" "prognostic favorable (5.10e-10)" "unprognostic (1.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.82e-2)" "unprognostic (5.22e-2)" 7.8 184.7 19.2 0.7 20.8 0.0 3.4 23.0 19.9 12.2 25.9 8.4 13.2 7.2 4.5 3.2 5.4 5.0 13.9 19.0 20.2 56.7 383.7 18.9 1.0 21.6 19.8 21.4 34.0 5.8 8.8 12.1 20.7 13.4 2.1 8.0 14.4 17.3 11.8 1.5 13.6 4.4 21.3 3.7 11.9 3.5 19.3 0.5 18.9 11.3 0.5 7.6 6.0 21.2 0.0 0.0 0.2 0.0 0.0 0.2 0.5 0.4 0.8 0.0 0.0 21.7 0.0 0.0 1.1 6.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 32.8 1.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 20.8 23.0 19.9 19.0 20.2 21.6 19.8 20.7 21.3 19.3 21.2 0.6 6.4 3.6 16.3 0.6 0.5 4.9 0.2 1.8 9.6 2.4 7.0 27.5 8.6 0.7 14.7 0.0 0.1 0.0 0.2 58.7 13.9 0.4 3.4 7.4 2.4 4.8 2.7 10.8 8.9 0.3 11.2 3.1 0.5 0.0 67.8 11.4 175.7 0.1 5.0 4.9 0.2 0.0 5.3 1.2 2.1 24.8 1.2 1.8 4.7 0.0 54.5 0.0 27.2 13.7 5.0 1.2 69.6 0.7 1.1 0.2 174.4 1.7 3.1 13.1 22.3 11.3 0.2 0.2 0.5 0.3 0.3 0.7 14.5 0.7 1.3 RGS6 ENSG00000182732 "Regulator of G protein signaling 6" P49758 14 71932429-72566530 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Astrocytes: 97.3;Early spermatids: 173.5;Excitatory neurons: 652.7;Inhibitory neurons: 256.1;Late spermatids: 298.0" "Group enriched" "Detected in some" 7 "glioma: 3.1;thyroid cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 11.5;Karpas-707: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003067 Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Vesicles" "HPA003067: AB_1079807" "unprognostic (7.18e-2)" "unprognostic (7.78e-2)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (5.61e-2)" "unprognostic (3.80e-2)" "unprognostic (1.24e-4)" "unprognostic (7.83e-2)" "unprognostic (2.03e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-2)" "unprognostic (8.64e-2)" "unprognostic (5.11e-2)" "unprognostic (8.06e-3)" "unprognostic (2.10e-1)" "unprognostic (3.68e-2)" 4.7 0.2 1.1 0.6 2.2 1.4 4.0 0.6 8.6 4.9 0.0 1.0 0.3 1.4 2.6 0.4 2.2 1.2 11.2 3.5 2.8 2.6 0.1 0.9 0.1 19.2 16.0 1.2 0.2 8.1 1.7 3.0 20.2 0.4 1.0 1.7 0.8 1.4 1.1 0.9 0.8 1.3 5.4 0.9 0.4 10.6 6.4 0.3 5.7 0.8 0.5 0.7 0.9 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 40.1 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.3 1.2 1.1 2.2 0.6 8.6 3.5 2.8 19.2 16.0 20.2 5.4 6.4 3.4 5.8 0.0 0.0 97.3 0.2 0.3 0.0 0.0 0.0 2.2 2.1 2.4 22.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 173.5 2.8 0.9 2.6 0.0 5.3 652.7 0.2 0.1 3.1 0.0 7.1 0.0 0.4 0.0 0.0 0.2 0.0 256.1 0.0 0.0 0.0 0.0 298.0 1.8 8.3 0.0 44.0 5.1 0.0 0.0 36.2 8.9 0.0 0.0 7.5 0.2 0.0 0.0 0.4 0.0 0.4 13.1 0.4 18.6 2.3 1.3 0.2 0.1 0.8 0.5 0.1 0.0 0.7 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117171 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 496.2;liver: 1536.9" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1579.1" "Group enriched" "Detected in all" 5 "liver cancer: 162.2;renal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 191.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favorable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 50.1 48.4 93.1 11.4 96.4 7.5 19.1 95.5 131.7 11.2 83.8 24.5 30.5 8.4 22.7 14.3 9.4 22.7 32.3 89.2 95.0 496.2 1536.9 9.5 10.1 91.6 97.8 23.4 27.0 24.6 10.0 10.8 95.5 19.3 24.6 26.6 16.4 11.6 40.0 10.6 21.8 10.8 92.6 7.4 24.8 17.2 100.0 11.2 15.9 41.0 12.3 15.5 7.9 91.0 44.0 37.5 29.3 36.6 65.5 50.4 33.0 39.7 28.0 26.4 31.0 51.4 28.4 62.5 49.6 29.4 34.5 30.8 65.4 56.9 52.5 22.3 28.6 45.0 25.6 55.6 29.9 17.6 7.0 44.4 19.5 36.6 39.9 32.4 34.2 65.3 82.7 12.9 35.5 57.8 35.6 50.1 47.0 191.4 67.8 41.0 21.7 18.4 64.6 31.6 32.2 15.7 25.5 17.4 29.2 37.4 44.5 23.5 20.9 20.6 12.5 33.7 16.3 31.2 46.1 30.9 35.0 39.0 13.2 0.2 9.0 5.6 6.6 7.8 8.7 13.8 9.4 10.1 11.1 11.5 12.0 13.0 1.9 10.3 8.3 8.5 13.9 8.1 93.1 96.4 95.5 131.7 89.2 95.0 91.6 97.8 95.5 92.6 100.0 91.0 7.8 25.6 22.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 13.8 15.1 0.0 0.0 1.8 47.8 0.0 31.1 3.2 0.0 285.7 19.7 0.0 25.1 12.3 5.0 0.0 0.0 0.0 8.5 29.9 7.9 0.0 9.4 2.5 17.7 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.8 0.0 0.0 1579.1 5.8 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 14.4 6.3 22.3 0.0 0.0 RILP FLJ31193 ENSG00000167705 "Rab interacting lysosomal protein" Q96NA2 17 1646145-1649866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.5;skeletal muscle: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.4;Proximal enterocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.5;eosinophil: 1.0;intermediate monocyte: 1.2;myeloid DC: 2.4;neutrophil: 3.3;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.3;monocytes: 3.5" "Cell line enhanced" "Detected in many" "HEL: 40.6;HMC-1: 19.5;K-562: 15.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 18000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" "prognostic favorable (7.97e-4)" "unprognostic (7.93e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-2)" "unprognostic (8.84e-3)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "prognostic favorable (8.51e-5)" "unprognostic (2.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.00e-1)" "prognostic favorable (7.12e-4)" 17.4 18.0 3.4 0.8 3.3 8.1 15.6 3.2 5.1 5.0 10.7 15.5 10.5 5.9 0.6 5.4 6.9 1.1 60.5 3.1 3.3 15.3 29.1 13.1 1.0 3.7 3.4 3.2 10.4 1.8 4.5 0.8 3.4 6.0 1.4 0.4 11.5 1.2 48.1 6.3 13.0 0.9 2.9 15.1 13.5 3.2 3.8 0.3 29.6 8.3 0.4 11.3 5.1 3.2 2.3 1.6 0.2 1.7 1.1 2.7 7.7 1.5 1.0 1.6 0.9 3.6 0.5 0.4 5.2 1.2 0.5 5.5 0.2 0.2 0.3 0.2 3.6 40.6 0.5 4.6 1.7 0.3 19.5 2.2 0.7 0.4 0.0 0.8 1.4 0.3 15.8 0.4 0.5 2.2 1.4 3.1 0.4 0.4 8.1 5.8 0.0 1.1 0.0 1.3 0.1 0.6 0.8 1.0 2.0 0.2 1.0 0.3 7.8 0.5 1.0 1.9 1.5 0.3 0.5 0.0 3.0 1.8 0.3 0.3 3.5 1.0 0.1 1.2 0.1 0.3 0.2 0.1 2.4 0.0 0.2 0.0 3.3 0.5 0.2 1.3 0.1 0.7 3.4 3.3 3.2 5.1 3.1 3.3 3.7 3.4 3.4 2.9 3.8 3.2 42.6 19.2 17.7 3.3 3.2 8.8 13.3 7.5 2.8 1.6 11.1 13.1 59.9 17.2 8.9 7.3 0.0 15.8 12.1 101.4 50.9 29.2 0.1 3.2 5.1 21.9 3.0 65.9 3.1 25.4 9.4 12.9 24.5 5.1 0.0 2.1 26.0 30.6 57.1 3.3 2.4 27.6 8.2 35.2 34.3 2.6 6.8 34.1 14.2 5.6 28.1 9.9 5.2 2.0 1.3 20.2 59.7 8.2 10.3 8.4 84.9 20.8 3.1 1.3 13.1 8.3 9.2 0.6 12.2 7.4 8.2 34.6 5.2 9.4 28.7 21.0 RIMKLA "FAM80A, MGC47816, NAAGS-II, RP11-157D18.1" ENSG00000177181 "Ribosomal modification protein rimK like family member A" Q8IXN7 1 42380792-42424232 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.0;retina: 11.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.9;Cone photoreceptor cells: 43.8;Distal enterocytes: 46.3;Excitatory neurons: 39.1;Horizontal cells: 35.3;Inhibitory neurons: 35.9;Rod photoreceptor cells: 24.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.4;JURKAT: 5.8;Karpas-707: 8.3;SCLC-21H: 9.9;U-266/70: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027826 Uncertain Uncertain "Nucleoli fibrillar center" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" "HPA027826: AB_10603992" "unprognostic (4.04e-2)" "unprognostic (1.61e-1)" "unprognostic (3.68e-3)" "unprognostic (9.84e-2)" "unprognostic (2.49e-2)" "unprognostic (1.06e-1)" "unprognostic (2.63e-3)" "prognostic favorable (1.43e-4)" "unprognostic (8.89e-2)" "unprognostic (3.76e-1)" "unprognostic (9.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" "unprognostic (7.07e-2)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" 0.2 0.2 2.9 0.4 3.6 0.0 0.2 3.7 15.0 0.1 0.0 3.0 0.3 0.1 0.0 0.1 0.2 0.5 3.2 4.5 2.3 0.8 0.1 1.9 0.1 5.7 2.2 0.0 1.0 2.2 1.2 0.2 6.2 0.5 3.2 11.2 0.5 0.2 0.7 0.2 0.4 0.6 1.2 0.2 1.0 0.7 6.2 0.0 0.6 1.0 0.0 0.4 0.2 6.3 0.0 0.7 0.1 6.4 0.1 0.0 1.3 0.0 0.0 0.2 0.5 0.3 0.2 0.0 1.4 0.0 1.2 0.0 4.2 0.0 0.3 3.7 2.5 0.3 0.1 1.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 8.3 0.0 0.3 2.0 0.0 3.5 0.5 5.1 0.0 0.2 0.3 0.6 1.7 9.9 4.2 0.3 0.3 0.1 0.7 0.3 1.9 0.0 0.0 0.4 0.0 0.7 7.4 4.4 5.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 2.9 3.6 3.7 15.0 4.5 2.3 5.7 2.2 6.2 1.2 6.2 6.3 0.9 16.0 3.9 1.3 0.2 0.6 1.1 1.0 0.0 25.9 0.9 1.0 14.4 1.5 1.1 1.8 43.8 1.4 0.3 46.3 1.9 3.3 5.3 0.4 0.0 2.2 11.4 0.0 39.1 4.8 20.1 0.5 0.5 0.1 0.0 0.3 0.7 0.0 1.0 35.3 35.9 8.0 2.0 0.3 1.4 10.5 0.3 0.3 5.4 2.8 0.0 5.1 0.0 7.1 3.9 9.4 14.2 0.0 0.1 1.7 0.3 3.7 0.2 24.6 0.0 0.8 0.6 1.1 4.8 0.0 0.1 1.6 0.7 0.3 5.2 1.0 RMDN1 "CGI-90, FAM82B, FLJ20665, RMD1" ENSG00000176623 "Regulator of microtubule dynamics 1" Q96DB5 8 86468257-86514357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026495 Approved Supported "Actin filaments,Centrosome" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Centrosome "Actin filaments" "HPA026495: AB_1848414" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (3.13e-3)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.02e-1)" "unprognostic (2.09e-1)" "unprognostic (1.60e-1)" "prognostic favorable (8.51e-4)" "unprognostic (2.08e-1)" "unprognostic (7.15e-2)" "unprognostic (4.71e-3)" "unprognostic (3.47e-1)" 35.6 26.1 25.8 20.9 30.1 24.7 24.3 30.4 27.8 15.5 25.3 26.7 28.7 17.6 19.8 29.4 21.1 22.5 63.0 23.0 29.5 51.7 56.8 23.4 30.3 29.8 29.7 17.0 17.5 26.3 12.9 18.9 30.0 21.2 29.0 30.9 16.4 20.7 71.7 32.8 29.2 20.2 28.3 25.2 30.6 26.4 29.6 23.0 50.4 70.5 31.5 20.1 16.3 30.5 64.0 27.1 31.3 17.8 60.3 97.8 38.5 45.9 41.1 35.8 34.6 32.2 39.9 76.2 38.1 38.2 33.2 61.0 39.8 46.0 42.1 64.6 31.9 40.2 32.8 82.1 32.1 18.4 1.0 53.3 42.6 47.6 72.9 63.9 81.6 44.3 42.4 40.7 57.5 57.3 65.1 8.6 15.9 111.3 67.5 36.6 43.6 78.9 42.5 39.3 14.8 32.8 38.2 149.2 67.6 32.5 83.9 33.6 44.6 39.5 64.0 50.8 28.2 52.4 46.5 59.7 51.2 28.7 54.4 16.4 38.5 94.2 26.6 50.7 31.1 42.2 27.1 31.3 45.2 30.8 22.3 29.0 15.5 39.0 70.3 51.3 43.2 30.7 25.8 30.1 30.4 27.8 23.0 29.5 29.8 29.7 30.0 28.3 29.6 30.5 24.0 41.7 39.0 38.8 23.8 13.5 13.2 40.1 22.2 14.5 16.8 15.0 117.3 20.0 42.4 20.2 16.7 42.5 29.9 22.2 49.0 42.9 97.8 28.3 26.6 24.3 10.2 27.3 22.5 53.0 57.1 24.0 32.1 24.8 1.3 18.9 21.8 57.7 53.7 20.2 29.9 20.6 18.3 40.1 14.8 77.1 13.1 28.3 16.0 33.7 48.5 27.4 21.6 42.3 51.9 45.8 17.2 9.1 21.8 9.2 45.7 73.0 34.4 21.5 0.0 19.9 32.9 65.7 33.5 31.0 15.5 28.5 21.6 53.1 26.9 15.2 RNF207 "C1orf188, FLJ32096, FLJ46380" ENSG00000158286 "Ring finger protein 207" Q6ZRF8 1 6205475-6221299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 34.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 31.8;Basal respiratory cells: 31.7;Club cells: 28.3;Urothelial cells: 37.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.2;HaCaT: 7.6;HeLa: 7.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA028378, HPA042535" Uncertain Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA028378: AB_10601157, HPA042535: AB_2678042" "unprognostic (5.53e-3)" "unprognostic (1.23e-1)" "unprognostic (1.62e-2)" "unprognostic (4.46e-2)" "unprognostic (4.84e-2)" "unprognostic (5.91e-3)" "unprognostic (9.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.57e-2)" "unprognostic (8.74e-2)" "unprognostic (9.93e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.76e-2)" "unprognostic (2.93e-2)" "unprognostic (1.89e-1)" "unprognostic (8.10e-3)" 3.3 3.3 3.2 1.3 3.2 0.0 3.1 4.0 4.2 9.5 5.9 5.8 2.0 4.3 1.5 5.9 7.9 0.9 34.7 3.2 3.1 9.8 7.6 1.7 0.9 3.7 2.9 2.5 6.9 1.2 5.5 1.2 3.7 11.8 1.4 2.1 6.7 3.8 1.7 1.2 4.4 1.2 2.6 1.4 4.1 1.2 3.2 0.5 6.7 4.2 1.3 6.3 5.4 3.0 2.6 4.5 0.4 2.9 0.2 0.3 3.1 1.3 1.0 0.2 0.3 2.2 17.2 0.2 1.3 1.1 0.0 7.6 0.4 1.0 0.1 2.8 1.7 0.1 7.0 2.2 1.3 1.7 0.1 1.1 0.2 0.0 0.0 3.8 0.1 0.3 0.7 3.6 0.1 1.8 0.2 0.3 0.2 0.3 3.8 0.0 0.7 2.9 2.2 3.9 0.4 1.1 2.8 1.5 1.1 0.7 2.7 0.1 0.5 0.0 0.8 0.4 0.0 3.9 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.2 3.2 4.0 4.2 3.2 3.1 3.7 2.9 3.7 2.6 3.2 3.0 2.9 9.6 3.9 2.0 1.7 0.3 31.8 31.7 6.2 4.0 4.4 4.3 19.5 14.3 28.3 18.4 2.1 15.6 0.4 8.5 0.0 15.4 0.7 2.3 6.8 2.9 3.6 0.4 13.2 9.8 6.3 4.6 17.3 2.7 0.0 1.7 1.1 3.9 1.1 3.3 13.2 15.6 10.2 0.0 0.7 0.2 0.0 1.6 0.0 0.0 2.2 7.5 0.0 3.5 1.7 19.0 3.5 1.2 1.5 21.3 9.5 3.5 10.1 16.3 6.6 1.5 5.0 0.1 2.8 3.8 0.4 5.6 1.9 2.0 6.4 37.1 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.7;Intestinal goblet cells: 41.6;Undifferentiated cells: 63.6" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 41.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.0;CACO-2: 24.7;Hep G2: 49.4;OE19: 54.7" HPA008079 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.2 10.9 1.7 2.0 3.1 0.7 5.5 9.6 2.7 2.6 1.5 13.4 22.7 1.7 4.4 10.4 4.8 2.7 2.7 2.0 1.3 6.1 9.1 3.6 0.4 1.8 3.4 0.9 8.2 5.2 4.3 4.8 1.9 9.4 19.3 1.2 9.3 4.8 0.3 11.3 16.9 0.6 1.4 0.5 5.8 3.4 2.3 3.7 1.9 0.0 1.5 2.1 5.2 1.4 1.1 17.0 2.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 24.7 8.2 0.0 8.5 0.0 1.9 4.6 0.6 6.8 0.0 8.6 11.3 1.9 0.8 49.4 0.0 0.2 0.1 0.0 13.4 0.0 2.1 0.0 0.0 0.2 0.2 0.4 0.0 0.2 0.1 0.2 0.4 54.7 1.0 0.3 0.0 2.2 5.9 9.0 1.6 0.1 1.6 0.7 0.5 5.4 2.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.4 0.1 0.3 0.0 3.8 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.2 0.0 1.7 3.1 9.6 2.7 2.0 1.3 1.8 3.4 1.9 1.4 2.3 1.4 0.3 3.2 8.9 29.0 2.5 9.6 17.5 14.1 67.7 2.5 17.3 13.6 4.0 17.2 5.8 18.4 2.1 26.0 2.2 33.0 15.6 5.3 1.2 14.6 1.1 1.8 15.5 0.8 1.8 2.7 3.1 0.7 9.7 12.7 0.0 7.2 0.7 11.9 2.6 5.0 1.3 41.6 12.2 0.8 0.9 1.5 0.3 1.3 14.2 4.7 2.8 12.0 10.3 0.0 0.7 6.2 21.1 0.4 1.0 9.9 28.7 2.9 5.6 2.8 0.0 0.5 1.1 1.0 0.8 28.4 6.1 5.9 3.1 0.4 63.6 6.3 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 371.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 38.2 75.9 60.4 29.2 63.4 40.4 44.5 64.6 66.0 44.9 59.4 59.5 61.6 44.8 45.8 37.5 54.1 46.1 81.7 59.2 60.6 115.6 126.2 38.7 43.1 65.0 60.6 60.4 41.6 55.5 17.2 30.1 62.6 44.0 62.4 42.9 43.9 31.7 89.6 44.6 76.5 30.5 62.8 38.8 55.3 29.5 61.8 60.7 48.6 76.5 43.4 45.1 38.8 67.0 51.2 66.1 43.7 167.5 46.9 31.3 34.0 20.6 26.5 44.4 48.7 89.1 42.1 65.2 70.8 47.9 62.5 41.7 80.3 45.1 45.2 41.8 107.5 53.9 69.5 184.4 55.0 0.2 101.2 32.3 60.3 73.3 53.6 77.2 89.1 115.0 136.6 67.8 63.8 71.9 66.5 151.5 0.3 71.8 28.7 44.4 48.2 88.2 124.0 32.6 44.8 92.1 39.9 42.4 46.7 39.9 87.0 183.0 40.3 48.1 44.7 0.5 79.1 38.6 63.5 79.3 33.2 116.4 29.6 64.8 45.7 75.8 64.8 65.9 55.6 64.6 52.5 57.6 64.7 56.2 57.5 58.3 22.1 79.6 46.7 264.6 58.2 75.0 60.4 63.4 64.6 66.0 59.2 60.6 65.0 60.6 62.6 62.8 61.8 67.0 38.3 19.2 41.1 2.9 52.7 95.7 70.0 146.6 52.3 23.6 61.8 56.5 62.9 87.2 79.5 92.0 0.0 78.1 70.3 151.9 283.7 110.8 21.6 47.2 31.7 50.9 73.2 126.3 3.4 91.3 101.7 44.6 28.5 31.7 56.3 41.5 47.8 131.5 68.9 33.7 3.5 83.0 132.2 51.1 171.7 22.6 59.4 43.3 85.4 1.0 69.5 91.3 65.9 1.5 10.0 78.5 173.0 72.6 45.5 58.4 270.6 371.6 73.4 27.6 65.7 50.6 63.0 55.7 37.7 44.4 84.4 84.1 53.8 42.8 100.3 56.5 RNLS "C10orf59, FLJ11218, renalase" ENSG00000184719 "Renalase, FAD dependent amine oxidase" Q5VYX0 10 88273864-88584530 "Enzymes, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 103.0;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 61.8;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 18.3;fHDF/TERT166: 17.1;HSkMC: 19.5" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 10500000000 "Cluster 7: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.27e-2)" "unprognostic (9.16e-2)" "unprognostic (1.27e-1)" "unprognostic (2.58e-1)" "unprognostic (1.46e-3)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (3.98e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (7.74e-3)" "unprognostic (1.37e-2)" "unprognostic (9.80e-2)" "unprognostic (1.71e-1)" 7.1 13.4 2.0 2.8 2.4 2.2 6.7 6.1 3.5 7.4 7.2 7.6 5.5 5.0 5.3 4.9 6.1 5.5 11.8 2.0 2.9 16.6 8.7 3.0 3.8 5.0 6.6 5.8 8.2 9.0 5.3 2.0 5.2 7.0 8.3 4.8 6.0 3.9 11.8 4.3 5.6 3.5 3.4 2.8 6.7 5.3 2.7 2.5 9.1 9.8 4.0 4.7 4.4 3.2 18.3 8.2 0.3 0.1 2.4 2.8 0.0 5.1 0.5 2.7 2.3 1.0 5.2 0.0 8.0 17.1 0.0 2.4 0.0 0.9 2.2 3.8 0.1 2.9 5.1 0.2 11.2 0.0 0.5 19.5 1.4 10.2 0.1 0.3 5.7 0.1 1.4 9.2 0.1 6.3 0.0 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 4.3 0.1 0.1 4.0 12.4 4.9 2.2 8.9 1.3 2.5 4.1 6.3 3.9 5.3 8.4 0.2 0.0 9.8 0.0 0.0 2.1 1.2 2.3 3.6 1.7 2.4 1.7 1.6 3.1 2.2 1.8 1.4 0.1 2.7 2.3 2.7 0.9 1.8 2.0 2.4 6.1 3.5 2.0 2.9 5.0 6.6 5.2 3.4 2.7 3.2 1.2 3.2 1.5 32.0 5.5 3.2 6.8 5.7 4.0 6.5 5.5 3.9 16.7 4.3 5.8 1.8 2.1 2.0 3.2 6.2 23.5 6.4 8.9 3.8 3.1 1.3 5.4 4.6 103.0 9.6 0.5 6.2 7.1 3.2 1.3 2.2 2.5 10.1 6.5 5.0 101.1 5.5 2.0 4.7 3.8 4.3 1.5 3.8 3.6 40.3 3.7 6.8 3.1 51.8 61.8 4.2 8.9 6.4 3.9 4.4 8.5 43.1 1.6 5.7 0.0 4.6 4.6 4.7 8.2 10.4 5.5 1.6 3.0 2.9 7.2 6.9 ROPN1B ENSG00000114547 "Rhophilin associated tail protein 1B" Q9BZX4 3 125969160-125983454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 214.2" "Group enriched" "Detected in many" 4 "Early spermatids: 2012.7;Late spermatids: 1967.9" "Group enriched" "Detected in some" 5 "breast cancer: 1.3;melanoma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SK-MEL-30: 54.6;WM-115: 18.5" HPA052530 Supported NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "HPA052530: AB_2681861" "unprognostic (7.73e-3)" "unprognostic (1.35e-2)" "unprognostic (2.22e-3)" "unprognostic (2.76e-2)" "unprognostic (7.19e-2)" "unprognostic (3.39e-2)" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (8.15e-2)" "unprognostic (1.96e-2)" "unprognostic (1.09e-2)" "unprognostic (8.18e-2)" "unprognostic (5.91e-2)" "unprognostic (5.01e-2)" "unprognostic (1.74e-2)" "unprognostic (6.89e-3)" "unprognostic (3.78e-2)" 0.3 0.5 1.3 0.2 1.6 0.1 38.2 2.0 1.8 0.2 0.0 0.1 0.1 0.3 22.1 0.1 0.5 0.0 3.0 1.3 1.2 0.3 1.2 0.3 0.6 0.8 1.3 0.3 0.3 0.0 3.0 0.2 0.9 0.7 0.0 1.8 14.6 0.2 0.4 7.0 0.1 0.0 0.5 0.1 0.1 214.2 0.9 0.0 0.7 0.8 0.3 0.4 0.1 2.0 0.0 0.0 0.3 0.2 0.0 0.0 2.9 0.0 0.3 0.2 0.2 0.2 2.4 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 1.4 0.0 0.1 1.1 0.2 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.3 0.9 0.3 0.1 0.0 54.6 0.1 0.7 0.7 0.0 0.0 0.5 0.2 0.2 5.4 1.1 0.3 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.6 2.0 1.8 1.3 1.2 0.8 1.3 0.9 0.5 0.9 2.0 0.6 0.0 0.0 1.3 0.3 3.7 0.1 1.4 0.0 0.2 60.1 86.2 18.8 0.0 3.9 0.0 0.0 0.3 2.0 0.0 0.0 0.2 2012.7 3.1 0.1 1.6 0.0 0.0 0.5 0.2 2.5 1.3 0.0 0.1 0.0 0.2 0.0 0.5 0.1 3.3 0.4 0.0 2.0 0.0 2.0 1967.9 19.0 1.5 149.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 9.8 0.0 0.6 0.0 0.1 17.8 0.2 19.7 0.0 1.0 493.4 11.8 0.0 0.6 0.1 0.5 0.0 0.0 1.2 RORC "NR1F3, RORG, RZRG, TOR" ENSG00000143365 "RAR related orphan receptor C" P51449 1 151806071-151831845 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 86.2;skeletal muscle: 128.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2;Hepatocytes: 47.8;Proximal enterocytes: 32.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 4.1" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 50.3" "Lineage enriched" "Detected in many" 44 "T-cells: 50.3" "Cell line enhanced" "Detected in some" "HDLM-2: 23.8;Karpas-707: 11.5;MOLT-4: 6.3;RPMI-8226: 6.0;SK-BR-3: 5.7;T-47d: 9.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA065620 Supported "Nuclear bodies" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear bodies" "HPA065620: AB_2685521" "unprognostic (6.51e-2)" "unprognostic (7.78e-2)" "prognostic favorable (1.83e-4)" "unprognostic (9.20e-2)" "unprognostic (3.05e-4)" "unprognostic (6.29e-5)" "unprognostic (1.13e-3)" "unprognostic (8.94e-2)" "unprognostic (1.67e-1)" "unprognostic (7.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.42e-1)" "prognostic favorable (2.94e-5)" "unprognostic (2.13e-1)" "unprognostic (3.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.80e-2)" 2.9 4.9 0.2 1.8 0.1 0.4 7.5 4.1 0.3 6.5 5.2 9.3 11.6 1.9 4.6 5.4 21.2 3.7 11.6 0.2 0.4 18.8 86.2 12.7 0.9 0.9 1.6 0.3 59.2 33.5 18.3 0.0 0.7 15.8 9.2 0.0 41.0 11.0 128.0 24.7 13.9 0.3 0.8 1.3 19.8 10.7 0.4 52.7 26.4 58.8 2.4 3.0 3.4 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.1 0.0 0.0 0.0 23.8 0.0 0.0 2.5 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 11.5 0.0 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.1 6.0 0.1 0.0 0.0 0.2 0.1 5.7 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 50.3 0.0 8.0 7.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 5.8 1.2 0.2 0.1 4.1 0.3 0.2 0.4 0.9 1.6 0.7 0.8 0.4 0.4 0.1 6.4 6.0 0.3 0.8 2.0 4.4 3.1 3.4 0.0 18.4 9.8 5.9 21.5 5.3 16.5 0.0 0.0 1.8 12.0 35.2 8.3 0.4 15.3 2.6 0.7 9.6 5.3 0.1 7.0 0.0 0.3 17.3 18.9 0.0 0.3 1.8 47.8 0.1 0.0 0.0 20.0 16.2 2.7 0.3 0.9 0.6 0.6 3.6 0.0 0.2 0.0 0.0 0.0 0.0 3.2 16.0 0.4 0.3 5.0 32.9 17.1 10.5 0.0 0.0 4.2 0.5 0.2 0.0 5.0 3.0 0.0 6.8 0.1 15.3 3.5 RPP25L "bA296L22.5, C9orf23, MGC29635" ENSG00000164967 "Ribonuclease P/MRP subunit p25 like" Q8N5L8 9 34610486-34612104 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 118.4" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 132.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052187, HPA059698" Uncertain Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA052187: AB_2681755, HPA059698: AB_2684106" "unprognostic (1.56e-1)" "unprognostic (1.43e-2)" "unprognostic (7.44e-2)" "unprognostic (1.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.78e-1)" "unprognostic (4.78e-2)" "unprognostic (2.56e-1)" "unprognostic (1.66e-1)" "unprognostic (2.53e-2)" "unprognostic (3.39e-2)" "unprognostic (2.44e-1)" "prognostic favorable (3.01e-9)" "unprognostic (4.63e-3)" "unprognostic (6.20e-2)" "unprognostic (3.40e-1)" "prognostic favorable (8.21e-4)" 17.2 23.2 30.5 13.8 31.7 9.7 18.3 32.7 36.2 20.6 28.4 26.4 27.5 19.9 12.5 28.2 20.1 14.5 46.8 30.5 31.5 30.6 51.4 11.8 20.7 31.9 30.6 19.5 23.0 24.0 17.4 12.2 32.3 24.5 14.4 4.8 23.1 15.1 118.4 17.5 26.4 10.5 30.8 26.5 21.9 16.0 33.0 22.5 18.5 103.1 13.9 20.5 18.5 30.2 42.6 54.0 21.9 21.4 21.4 20.2 21.5 18.1 18.5 28.9 33.1 24.3 28.2 32.8 27.1 11.0 13.5 28.1 33.2 44.2 10.4 66.1 44.5 19.5 37.9 36.2 46.1 20.5 28.3 35.2 42.4 24.3 55.3 25.1 30.8 44.5 31.6 34.1 22.7 45.8 42.9 76.4 20.1 43.4 48.7 37.2 23.0 33.2 31.9 22.1 14.6 8.5 32.9 36.6 21.6 10.8 33.6 35.7 14.5 9.1 26.3 22.3 15.1 16.4 30.8 38.6 27.6 41.3 44.7 71.2 55.6 56.4 38.2 48.5 47.3 57.1 44.5 40.3 47.8 67.3 51.8 49.8 51.9 56.6 57.5 39.3 68.4 39.6 30.5 31.7 32.7 36.2 30.5 31.5 31.9 30.6 32.3 30.8 33.0 30.2 12.9 0.0 15.1 6.5 20.7 11.1 50.4 61.9 24.5 7.8 30.9 39.9 34.4 22.8 30.5 20.2 2.1 61.8 14.4 55.7 99.7 31.0 3.3 10.3 21.5 17.5 33.6 12.6 3.0 19.8 38.1 18.4 17.9 13.7 10.2 16.4 27.1 77.5 32.0 0.0 3.9 44.7 38.7 33.6 10.4 6.0 22.4 18.4 12.4 3.7 33.1 25.6 51.5 2.0 3.4 18.9 61.6 15.4 14.7 40.8 132.7 82.2 21.0 12.3 6.6 18.2 18.8 50.3 24.0 30.6 14.8 41.9 17.4 47.7 50.1 44.4 RRAGD "bA11D8.2.1, DKFZP761H171" ENSG00000025039 "Ras related GTP binding D" Q9NQL2 6 89364616-89412273 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 129.1;Distal tubular cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;monocytes: 2.4" "Cell line enhanced" "Detected in many" "Karpas-707: 63.9;SCLC-21H: 33.1;U-266/70: 80.0;U-266/84: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068664 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Centrosome" "HPA068664: AB_2686016" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.53e-3)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.80e-4)" "unprognostic (3.75e-2)" "unprognostic (1.66e-2)" "unprognostic (4.33e-2)" "unprognostic (1.11e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.47e-8)" "unprognostic (8.41e-3)" "unprognostic (1.23e-1)" "unprognostic (9.46e-2)" "unprognostic (4.40e-2)" 9.8 9.1 14.0 2.3 18.9 11.6 8.2 31.8 16.1 9.4 17.9 4.0 1.7 1.5 6.9 13.8 13.7 3.6 38.4 15.9 13.9 26.5 4.4 7.0 2.8 16.4 12.2 1.6 6.4 22.7 11.4 3.2 17.2 6.1 1.8 21.8 52.2 2.8 84.5 6.7 2.0 2.1 21.5 4.8 1.7 6.9 14.8 5.5 28.1 60.3 2.5 5.8 6.2 23.8 0.1 1.7 4.4 3.3 0.4 0.0 0.3 0.0 0.0 0.5 0.9 0.1 0.1 0.0 1.5 0.0 22.6 0.1 24.5 0.1 0.0 0.0 12.1 5.8 0.1 0.1 1.8 16.9 19.0 0.4 1.5 0.0 0.1 0.0 0.0 16.9 0.5 63.9 0.1 1.8 8.2 8.4 3.6 0.0 1.8 16.8 23.1 0.2 5.8 0.6 33.1 1.8 0.6 2.2 28.8 1.3 0.7 13.2 0.0 1.8 2.8 11.5 3.0 80.0 39.8 0.0 6.1 12.5 1.9 2.6 0.6 1.4 0.0 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.3 3.3 0.1 2.4 0.3 0.0 0.1 14.0 18.9 31.8 16.1 15.9 13.9 16.4 12.2 17.2 21.5 14.8 23.8 1.4 9.6 16.7 5.2 3.7 16.2 17.0 5.8 4.0 21.7 17.4 9.7 129.1 17.2 13.9 14.7 31.3 0.6 4.7 0.1 117.4 20.2 25.6 10.4 2.5 4.8 1.2 5.0 17.6 16.9 1.5 10.0 1.1 15.0 4.5 2.9 2.5 9.7 51.9 47.1 20.6 0.5 42.7 25.8 9.2 15.5 3.1 23.2 39.2 3.7 10.4 29.6 0.0 13.0 17.2 8.1 0.0 4.1 8.0 28.4 0.0 18.6 19.4 16.3 0.0 11.8 7.0 21.7 30.3 32.4 22.6 0.7 3.9 0.2 0.2 30.2 RTN4IP1 NIMP ENSG00000130347 "Reticulon 4 interacting protein 1" Q8WWV3 6 106570771-106629498 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036357 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA036357: AB_10673128" "prognostic unfavorable (9.18e-6)" "unprognostic (5.87e-2)" "unprognostic (2.20e-3)" "unprognostic (2.88e-1)" "unprognostic (3.51e-2)" "unprognostic (3.71e-2)" "unprognostic (7.37e-3)" "unprognostic (1.57e-1)" "unprognostic (7.77e-2)" "unprognostic (3.35e-1)" "unprognostic (2.51e-2)" "unprognostic (1.72e-2)" "prognostic favorable (8.55e-6)" "unprognostic (1.62e-1)" "unprognostic (9.82e-2)" "unprognostic (3.71e-1)" "unprognostic (5.76e-2)" 2.5 6.8 2.8 3.1 3.0 1.8 3.2 3.3 3.9 2.6 3.3 6.3 4.8 2.7 5.5 4.2 2.7 1.6 14.7 2.7 2.7 6.4 7.4 2.0 4.6 2.5 2.5 2.2 3.2 5.2 4.5 2.2 2.8 2.7 6.0 6.0 4.6 2.7 15.6 2.9 4.5 2.9 2.5 4.2 5.9 5.5 2.8 3.0 4.0 15.4 6.1 2.9 2.8 3.4 7.6 10.8 7.3 12.6 5.9 3.5 8.6 5.0 7.0 7.7 7.4 17.4 4.1 11.6 7.6 6.5 15.1 10.8 13.0 10.7 12.1 8.1 7.4 12.1 8.4 14.0 6.1 12.5 8.1 5.2 8.3 10.3 6.7 4.7 6.9 16.3 21.7 4.7 8.5 11.3 4.7 14.4 9.1 10.7 7.9 16.1 13.3 8.8 12.4 8.1 7.1 5.7 4.7 12.3 11.2 7.5 15.5 8.0 3.6 4.4 6.1 8.8 8.9 3.5 5.7 24.8 11.5 18.1 9.6 0.1 4.6 2.2 3.2 5.1 3.3 11.4 4.4 3.4 10.7 16.0 4.0 3.9 0.8 6.5 3.7 5.6 8.2 3.3 2.8 3.0 3.3 3.9 2.7 2.7 2.5 2.5 2.8 2.5 2.8 3.4 1.6 0.0 2.8 7.8 8.1 0.8 1.9 6.4 0.6 5.5 2.8 1.7 18.4 4.3 3.1 1.8 8.4 12.5 1.3 5.2 27.4 6.7 8.5 7.6 2.0 2.1 4.2 1.3 15.6 8.6 15.0 2.1 4.1 4.2 2.5 3.6 2.5 5.5 7.3 0.0 17.2 3.0 10.2 5.4 1.8 3.4 0.6 3.6 0.0 8.4 0.9 3.7 1.0 6.6 17.5 4.9 3.0 1.9 4.2 1.2 3.3 14.5 5.4 6.2 13.1 2.1 2.5 11.9 16.7 4.1 1.0 5.6 2.8 5.6 6.4 2.0 S100A1 "S100-alpha, S100A" ENSG00000160678 "S100 calcium binding protein A1" P23297 1 153627926-153632039 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 3076.8;skeletal muscle: 3060.2;tongue: 4911.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 1848.3" "Group enriched" "Detected in all" 5 "melanoma: 210.5;ovarian cancer: 110.1;thyroid cancer: 123.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Hep G2: 325.8;SK-MEL-30: 1130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002599, HPA006462" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 290000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nucleoplasm, Golgi apparatus" "CAB002599: AB_2315307, HPA006462: AB_1079857" "unprognostic (6.13e-2)" "unprognostic (7.60e-2)" "unprognostic (5.96e-5)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.19e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (2.34e-3)" "unprognostic (6.83e-3)" "unprognostic (5.22e-1)" "unprognostic (5.04e-3)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.68e-1)" "unprognostic (4.56e-2)" "unprognostic (2.70e-3)" "unprognostic (9.74e-4)" 179.7 8.3 811.3 6.5 898.6 2.3 77.2 851.4 952.4 2.9 643.9 14.5 11.1 4.2 1.0 81.0 41.8 4.9 3076.8 779.4 813.6 194.9 4.5 3.9 5.1 907.6 894.8 2.0 16.8 160.9 54.6 18.1 871.2 29.0 1.2 36.5 622.1 9.3 3060.2 23.0 6.9 1.6 847.7 4.2 23.1 5.9 882.9 9.4 167.9 4911.5 4.0 4.3 2.9 967.6 6.0 3.4 3.9 33.7 0.5 0.2 2.9 7.7 0.2 0.6 0.2 6.6 3.4 3.7 137.7 0.6 2.7 10.3 0.3 0.4 0.0 4.2 3.3 8.2 5.4 325.8 0.4 3.0 2.3 0.7 0.0 0.0 0.1 7.9 0.0 1.5 27.2 3.7 0.1 10.6 1.2 4.9 1.8 4.3 2.6 22.5 3.3 8.0 6.0 12.1 6.1 1.9 3.5 10.6 1130.2 11.1 32.8 16.2 2.7 3.3 2.8 3.0 3.8 6.1 5.7 6.2 2.5 6.2 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 811.3 898.6 851.4 952.4 779.4 813.6 907.6 894.8 871.2 847.7 882.9 967.6 4.3 0.0 0.0 59.4 9.5 9.7 1.2 0.4 1.8 1.1 369.9 354.1 74.4 8.6 0.2 154.5 2.1 1.1 5.9 1.1 162.4 0.9 0.6 90.5 17.3 5.3 1.8 0.0 0.3 3.7 1.9 6.0 0.0 193.3 0.0 0.0 7.9 4.7 199.1 0.0 0.3 3.7 0.0 0.6 3.5 2.2 6.5 15.6 341.5 2.8 0.0 163.5 0.0 2.0 45.8 1.9 0.6 9.1 0.0 1.8 0.9 1848.3 0.2 2.7 0.0 67.0 4.2 3.8 2.8 1.0 2.3 3.4 8.2 2.3 1.8 0.7 S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2340.8;Paneth cells: 1098.9;Proximal enterocytes: 1549.1;Squamous epithelial cells: 3205.8;Suprabasal keratinocytes: 3612.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 798.6;HaCaT: 1072.9;HBEC3-KT: 1527.6;hTCEpi: 2232.0;OE19: 1675.1;SK-BR-3: 1579.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" 2.2 0.8 1.5 24.9 1.6 0.2 78.3 1.5 2.0 530.8 1.3 241.0 265.4 5.4 14.7 3719.5 20.4 18.5 4.2 1.5 1.5 70.1 16.3 82.7 0.6 1.5 1.5 1.4 17.7 125.2 5.1 1.1 1.5 19.6 240.0 0.0 550.3 39.0 2.2 608.0 209.0 13.1 1.4 1.3 119.2 0.7 1.7 149.0 98.6 0.0 449.7 32.9 1174.2 1.5 798.6 0.2 0.1 0.2 0.2 0.3 7.4 0.2 0.1 0.2 0.1 97.6 140.1 0.6 2.3 0.2 0.5 1072.9 0.0 1527.6 0.1 0.5 0.3 0.1 10.8 7.3 0.0 0.0 0.9 0.6 2232.0 0.5 20.7 0.3 0.3 0.1 0.6 1.1 0.2 140.0 0.7 1.1 0.4 1675.1 1.9 0.6 0.6 2.8 8.1 51.2 0.7 0.7 2.2 1579.1 2.1 36.5 3.9 1.7 0.0 0.7 0.8 1.1 2.0 0.4 0.8 0.9 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.6 1.5 2.0 1.5 1.5 1.5 1.5 1.5 1.4 1.7 1.5 2.7 60.9 162.6 2.3 4.2 2340.8 448.6 770.5 657.9 0.0 256.2 178.3 5.3 270.2 387.7 35.0 0.0 2.7 2.2 1058.2 49.0 197.5 0.0 37.3 6.4 21.5 153.4 0.0 0.0 65.8 1.5 22.8 85.6 80.3 28.0 0.2 1.1 9.5 0.3 0.0 0.0 660.1 126.1 0.3 213.7 0.0 0.0 3.0 241.9 0.0 2.0 0.0 0.0 0.0 0.1 343.0 1098.9 0.0 7.5 619.3 1549.1 4.9 56.2 0.0 0.0 1.3 27.1 0.0 0.0 3205.8 3612.0 0.3 8.7 13.6 580.9 824.9 SAMM50 "CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W" ENSG00000100347 "SAMM50 sorting and assembly machinery component" Q9Y512 22 43955442-44010531 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034537 Enhanced Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034537: AB_10602794" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.95e-3)" "prognostic favorable (2.63e-7)" "unprognostic (2.43e-3)" "unprognostic (2.28e-1)" "unprognostic (5.28e-3)" "unprognostic (1.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.42e-1)" "unprognostic (3.52e-1)" "prognostic favorable (4.43e-8)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" 41.7 50.6 26.1 27.0 27.0 32.5 35.8 29.8 30.6 43.4 31.1 35.6 50.8 27.0 29.3 31.7 41.9 29.3 65.5 27.1 29.2 48.8 37.2 22.2 34.6 29.8 28.5 40.0 33.3 114.4 24.4 20.1 30.4 26.5 35.5 25.5 35.2 25.1 240.4 35.9 38.3 27.7 27.0 24.4 43.8 26.1 28.5 34.4 28.1 177.0 37.0 27.9 24.0 28.0 64.6 59.8 57.1 69.5 72.2 75.9 79.8 61.7 65.7 89.1 76.4 86.1 46.0 105.9 44.3 70.8 51.4 75.6 85.4 82.6 79.7 29.4 105.3 57.5 73.9 102.6 50.4 184.0 83.1 88.3 64.7 77.0 35.5 62.3 93.1 49.9 49.9 34.0 80.9 91.7 72.6 72.0 56.0 77.4 70.9 83.8 61.8 85.9 74.4 81.0 34.1 55.4 68.3 72.2 104.1 60.4 67.7 59.8 57.7 57.3 68.8 53.6 51.2 50.1 74.4 82.1 72.0 66.3 58.7 47.5 39.2 46.9 39.8 39.0 55.4 55.1 36.6 40.5 67.7 51.0 37.8 36.0 6.1 39.1 31.8 26.7 45.7 40.2 26.1 27.0 29.8 30.6 27.1 29.2 29.8 28.5 30.4 27.0 28.5 28.0 52.9 35.3 18.9 10.4 31.6 20.6 27.0 72.0 30.7 20.1 32.1 40.9 68.6 18.6 39.5 9.2 8.4 41.6 31.7 36.1 60.7 47.2 40.3 47.3 24.9 35.1 18.6 51.4 12.0 55.5 54.1 24.6 42.3 32.7 27.3 43.9 30.0 41.8 51.1 32.0 12.7 35.2 46.8 28.6 20.5 50.1 26.1 25.0 16.0 12.2 41.4 32.8 33.0 9.5 9.1 43.7 34.5 30.5 31.0 16.2 82.4 116.8 39.9 30.1 19.7 23.2 33.4 45.8 31.2 34.3 22.6 20.5 28.5 69.9 59.8 19.3 SARS2 "FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS" ENSG00000104835 "Seryl-tRNA synthetase 2, mitochondrial" Q9NP81 19 38915266-38930763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.1;Late spermatids: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA052730, HPA056957" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (3.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.88e-3)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.57e-2)" "unprognostic (8.62e-3)" "unprognostic (8.36e-2)" "unprognostic (1.67e-1)" "unprognostic (5.62e-3)" "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.69e-2)" 7.3 17.3 4.2 7.2 4.7 9.3 8.2 4.4 6.8 9.7 3.6 10.1 9.3 9.3 2.8 14.3 8.5 5.9 12.4 4.7 4.4 14.6 18.7 6.6 9.8 5.0 4.4 9.8 15.9 7.8 11.9 7.6 5.3 12.2 5.3 2.3 11.3 6.2 16.4 12.3 10.2 5.1 4.2 12.0 11.9 10.7 4.4 7.5 14.4 11.5 6.6 9.4 9.6 5.4 17.6 47.3 15.5 10.7 5.8 13.3 23.7 10.7 12.6 23.1 17.7 36.0 18.4 17.2 16.3 12.5 9.7 13.9 14.7 29.2 5.3 12.7 24.4 33.7 17.7 32.0 15.4 29.1 31.9 20.7 13.5 14.5 7.6 9.5 14.2 26.3 29.9 14.2 10.6 28.4 21.4 20.7 18.5 21.6 8.5 31.2 16.4 18.6 20.5 36.2 29.1 18.1 14.2 32.7 8.9 4.6 21.8 19.1 11.4 13.7 17.7 11.7 15.1 11.0 7.1 13.2 10.9 18.5 13.8 0.0 8.0 1.0 14.2 14.4 11.5 12.0 10.7 14.7 25.2 10.7 7.5 8.6 0.5 14.0 13.7 9.9 13.4 8.9 4.2 4.7 4.4 6.8 4.7 4.4 5.0 4.4 5.3 4.2 4.4 5.4 2.7 6.4 7.9 6.2 8.4 4.2 3.8 8.3 3.4 8.0 7.0 5.3 8.1 7.2 6.8 5.5 8.4 40.1 5.6 8.9 15.6 15.5 15.7 3.6 3.6 3.8 11.4 13.2 6.8 12.7 23.0 4.8 9.7 3.9 5.7 7.4 6.1 10.1 12.9 5.0 6.7 9.2 10.2 6.7 4.2 56.9 4.7 4.8 3.6 1.9 7.7 3.1 5.2 1.5 3.1 8.4 5.6 4.9 10.1 2.6 7.4 10.3 5.1 13.4 0.0 2.7 4.2 1.9 8.2 12.8 4.1 29.1 7.4 10.6 17.8 3.2 SBK1 Sbk ENSG00000188322 "SH3 domain binding kinase 1" Q52WX2 16 28259246-28323849 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.8;skeletal muscle: 44.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Excitatory neurons: 38.2;Granulosa cells: 26.3;NK-cells: 36.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 28.8;AN3-CA: 20.9;NTERA-2: 29.6;REH: 32.6;SCLC-21H: 45.5;SH-SY5Y: 42.6" "Region enriched" "Detected in all" 5 "cerebellum: 275.9" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.15e-2)" "prognostic favorable (6.88e-4)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (5.71e-3)" "unprognostic (3.66e-3)" "unprognostic (1.17e-1)" "unprognostic (1.62e-2)" "unprognostic (2.87e-2)" "unprognostic (6.38e-2)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (3.50e-2)" "unprognostic (7.91e-2)" "unprognostic (5.03e-3)" 0.1 2.4 8.0 0.9 7.0 1.3 0.8 26.8 15.0 0.7 0.0 0.3 0.3 0.9 0.4 0.6 0.7 0.2 2.1 11.6 6.7 1.8 0.2 0.8 1.7 6.6 7.6 0.5 1.9 2.9 5.6 0.0 6.7 1.5 0.3 5.0 2.7 0.2 44.1 1.1 0.6 0.1 3.2 1.9 0.8 2.5 12.8 10.0 2.5 9.1 0.8 0.3 0.3 7.9 0.3 0.4 28.8 20.9 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.2 1.4 0.7 0.2 0.0 0.4 0.5 8.8 0.2 0.1 3.0 1.2 0.1 0.3 0.9 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.2 0.2 11.2 0.0 1.8 0.0 3.6 14.0 0.3 29.6 1.9 0.2 32.6 1.6 0.6 0.1 1.8 45.5 42.6 0.8 2.7 0.4 3.5 3.3 0.1 0.8 0.1 4.3 0.4 0.2 0.3 0.0 0.5 0.1 0.5 1.6 0.3 0.0 0.0 1.5 0.0 0.5 0.0 0.4 0.8 0.0 0.1 0.4 1.0 0.0 0.7 0.0 0.0 0.5 0.1 8.0 7.0 26.8 15.0 11.6 6.7 6.6 7.6 6.7 3.2 12.8 7.9 0.2 3.2 0.5 1.0 0.6 0.6 0.7 1.4 3.4 13.0 6.3 2.9 3.6 2.8 2.5 0.0 81.3 0.0 11.1 0.1 1.9 8.2 1.2 2.4 0.3 0.3 6.0 0.4 38.2 5.6 0.0 0.4 0.0 1.8 0.0 26.3 0.0 0.2 0.1 0.0 13.8 0.8 4.1 0.0 0.8 3.9 0.6 0.4 0.0 0.0 0.7 4.1 36.0 5.0 1.7 3.6 0.0 0.0 2.3 1.5 0.1 0.7 1.7 2.7 0.0 2.5 2.7 2.4 2.1 1.0 0.1 0.1 5.6 0.2 1.2 0.4 SBK2 SGK069 ENSG00000187550 "SH3 domain binding kinase family member 2" P0C263 19 55528611-55537133 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 28 "heart muscle: 87.2;tongue: 28.8" "Group enriched" "Detected in some" 6 "Early spermatids: 1.5;Late spermatids: 2.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.5;MCF7: 2.5;NTERA-2: 7.7;RH-30: 7.0;SuSa: 3.5;U-2 OS: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030631 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 38: Heart - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 31: Spermatids - Spermatogenesis" "HPA030631: AB_10602088" "unprognostic (1.33e-1)" "unprognostic (1.85e-3)" "unprognostic (4.57e-1)" "unprognostic (3.49e-1)" "unprognostic (5.43e-3)" "unprognostic (4.18e-3)" "unprognostic (2.08e-1)" "unprognostic (6.58e-2)" "unprognostic (1.05e-1)" 0.6 0.0 0.1 0.0 0.2 0.5 0.0 0.9 0.1 0.0 0.8 0.0 0.2 0.3 0.0 0.2 0.0 0.1 87.2 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.4 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 28.8 0.0 0.0 0.0 0.3 0.0 2.5 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.6 1.3 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.1 2.2 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.5 2.5 0.0 0.1 7.7 0.0 0.0 0.2 7.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 3.5 0.0 0.2 0.1 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.9 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1227.2;cervix: 4002.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3242.1;Glandular and luminal cells: 3417.9" "Group enriched" "Detected in many" 6 "breast cancer: 625.1;endometrial cancer: 226.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 10.4" HPA035318 Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "HPA035318: AB_10610421" "unprognostic (8.76e-2)" "unprognostic (2.14e-1)" "prognostic favorable (3.46e-6)" "unprognostic (2.39e-2)" "unprognostic (5.89e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "prognostic favorable (8.03e-6)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" 12.9 4.9 4.1 0.0 4.0 0.0 1227.2 3.2 5.4 4002.8 13.8 0.3 0.1 89.0 355.8 10.1 110.3 0.1 3.1 3.5 4.4 10.1 0.2 0.1 0.1 4.7 5.7 1.1 4.5 0.5 5.2 0.2 4.2 8.6 0.2 1.8 69.2 2.9 7.2 342.4 0.4 0.0 3.5 0.0 0.3 0.2 4.3 0.4 0.6 6.0 0.0 0.2 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.1 0.0 1.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.0 3.2 5.4 3.5 4.4 4.7 5.7 4.2 3.5 4.3 4.6 2.1 0.0 0.0 0.0 1.6 27.4 4.8 0.0 0.0 0.5 647.8 251.6 10.9 0.0 0.0 7.3 0.0 0.0 5.3 0.0 23.5 0.3 0.0 3242.1 409.9 12.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 3417.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 15.0 823.6 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 46.1 0.0 0.9 0.0 0.2 8.6 0.0 0.0 0.0 7.0 0.1 20.0 0.0 0.0 1.1 SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 24.7" "Group enriched" "Detected in some" 11 "Excitatory neurons: 409.9;Inhibitory neurons: 494.6;Oligodendrocyte precursor cells: 692.1" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 6.1;Hep G2: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: AB_2686888" "unprognostic (9.25e-2)" "unprognostic (3.97e-2)" "unprognostic (6.88e-2)" "unprognostic (7.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "unprognostic (4.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-1)" "unprognostic (9.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.03e-9)" "unprognostic (6.92e-2)" "unprognostic (3.69e-2)" "unprognostic (5.06e-3)" "unprognostic (6.93e-1)" 0.0 0.0 4.2 0.0 4.2 0.0 0.0 2.1 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.1 6.9 0.0 0.0 1.4 0.0 14.2 6.2 0.0 0.0 0.0 2.0 0.0 18.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.9 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.2 2.1 24.7 2.1 6.9 14.2 6.2 18.5 2.2 10.9 10.9 0.0 6.4 33.9 27.4 0.0 0.0 0.0 0.0 0.0 47.4 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.5 0.0 0.3 1.8 0.0 409.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 494.6 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 18.7 0.0 2.8 0.0 692.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SCN2B ENSG00000149575 "Sodium voltage-gated channel beta subunit 2" O60939 11 118162806-118176639 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.0;heart muscle: 12.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.8;Cardiomyocytes: 16.8;Excitatory neurons: 21.9;Horizontal cells: 13.5;Inhibitory neurons: 32.0;Oligodendrocytes: 7.4" "Cancer enhanced" "Detected in some" "glioma: 1.3;thyroid cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (9.01e-2)" "unprognostic (3.50e-2)" "unprognostic (7.58e-2)" "unprognostic (2.12e-2)" "unprognostic (1.41e-2)" "unprognostic (4.02e-1)" "unprognostic (2.71e-4)" "unprognostic (5.17e-2)" "unprognostic (8.59e-2)" "unprognostic (2.77e-1)" "unprognostic (7.89e-2)" "unprognostic (1.61e-2)" "unprognostic (3.51e-2)" "unprognostic (1.27e-2)" "unprognostic (4.35e-2)" "unprognostic (4.55e-1)" "unprognostic (2.88e-3)" 0.6 1.5 19.1 0.3 20.7 0.0 0.7 14.9 34.0 1.4 0.0 1.7 0.6 1.6 1.3 1.8 1.3 1.3 12.8 20.9 12.3 0.4 0.0 1.1 0.0 5.7 13.3 1.3 0.1 0.0 0.8 0.0 9.1 1.0 0.7 3.7 0.5 1.2 7.3 0.2 1.1 1.9 4.9 0.1 0.3 0.2 19.5 1.8 0.7 7.5 0.0 0.3 0.4 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 19.1 20.7 14.9 34.0 20.9 12.3 5.7 13.3 9.1 4.9 19.5 22.1 0.1 0.0 0.0 3.9 0.0 0.4 0.6 0.7 1.8 8.8 0.1 2.0 16.8 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.5 0.2 0.0 0.0 21.9 0.0 0.0 1.6 0.0 0.3 0.0 0.2 0.0 0.0 0.1 13.5 32.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 1.9 0.0 0.9 0.0 2.5 7.4 0.0 0.0 2.2 0.0 0.2 0.0 0.0 0.1 1.9 0.0 0.9 0.8 0.1 0.6 0.0 0.1 0.0 0.1 0.5 0.0 0.3 SCN5A "CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1" ENSG00000183873 "Sodium voltage-gated channel alpha subunit 5" Q14524 3 38548057-38649687 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Calmodulin-binding, Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Cardiomyopathy, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "heart muscle: 42.8" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 77.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "LHCN-M2: 27.6;RH-30: 22.8" "Group enriched" "Detected in many" 5 "amygdala: 3.1;basal ganglia: 10.1;hypothalamus: 6.0" "Region enhanced" "Detected in many" "basal ganglia: 5.4" HPA063346 Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA063346: " "unprognostic (9.29e-4)" "unprognostic (4.05e-2)" "unprognostic (9.95e-2)" "unprognostic (1.74e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (8.48e-2)" "unprognostic (7.12e-3)" "unprognostic (5.28e-2)" "unprognostic (1.16e-4)" "unprognostic (4.85e-3)" "unprognostic (1.09e-1)" "unprognostic (5.35e-2)" "unprognostic (4.95e-3)" 0.2 0.1 1.9 0.1 1.2 0.2 0.2 0.0 0.7 1.7 0.0 0.2 0.2 0.7 0.0 0.1 0.3 0.1 42.8 0.2 1.5 0.0 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.2 0.0 0.3 0.1 2.0 0.2 0.5 1.6 0.1 0.2 0.3 0.2 0.1 0.1 0.3 2.6 0.0 0.2 1.0 0.0 0.4 0.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.4 0.1 0.0 0.2 3.6 0.0 0.0 0.0 1.0 0.5 2.7 0.0 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.4 0.0 2.1 2.8 0.4 0.0 0.0 27.6 1.4 0.0 0.0 2.6 0.0 0.0 0.0 22.8 0.0 0.0 3.2 0.4 3.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.7 0.2 1.5 0.0 0.7 0.0 0.2 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 2.7 0.0 0.3 77.1 0.0 0.1 0.0 14.6 0.2 0.0 0.0 0.0 0.1 1.2 0.1 3.2 2.8 0.0 0.0 0.5 0.0 0.3 3.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 6.3 0.3 0.6 0.2 0.0 3.7 0.0 0.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.9 0.0 7.3 3.1 0.2 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.4 SDHAF4 "C6orf57, Sdh8" ENSG00000154079 "Succinate dehydrogenase complex assembly factor 4" Q5VUM1 6 70566917-70589569 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031824 Supported Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "HPA031824: AB_10602113" "unprognostic (8.72e-2)" "unprognostic (1.64e-1)" "unprognostic (4.95e-2)" "unprognostic (9.96e-2)" "unprognostic (4.58e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (1.42e-3)" "unprognostic (3.18e-2)" "unprognostic (3.17e-1)" "prognostic favorable (1.95e-5)" "unprognostic (2.45e-2)" "unprognostic (9.37e-2)" "unprognostic (3.05e-1)" "unprognostic (9.94e-2)" 11.2 12.3 7.1 4.2 7.5 4.3 10.5 6.8 10.5 6.6 7.3 6.8 5.0 5.8 9.3 7.5 10.3 4.2 14.5 7.6 9.4 12.5 8.5 5.4 6.0 6.9 6.3 6.4 6.6 14.4 12.7 6.8 7.3 7.6 6.7 10.0 8.7 5.4 23.6 8.6 5.4 4.2 5.8 5.6 7.0 5.3 7.8 6.4 7.3 10.6 5.2 6.8 6.7 7.6 13.3 4.2 18.8 11.6 9.0 13.6 3.5 7.1 5.1 3.4 5.0 3.8 11.3 9.1 12.7 3.8 8.0 2.3 6.2 5.9 5.2 18.3 4.3 6.6 1.8 3.9 15.3 6.3 5.1 9.6 19.3 2.6 14.8 11.6 8.0 14.8 4.2 13.9 11.0 9.0 5.9 15.7 8.8 6.5 4.5 6.4 12.6 10.8 14.9 4.4 16.8 12.1 4.3 2.1 9.6 8.0 9.6 16.5 6.3 3.5 2.7 2.8 7.7 6.2 4.5 3.1 3.9 15.1 8.5 4.0 4.6 4.4 3.4 4.3 3.3 3.7 3.7 4.1 5.1 4.7 3.9 3.8 3.3 4.7 4.6 6.2 4.2 3.0 7.1 7.5 6.8 10.5 7.6 9.4 6.9 6.3 7.3 5.8 7.8 7.6 5.4 12.8 13.9 4.9 3.3 0.0 7.9 0.0 3.4 7.4 6.5 7.5 21.3 10.0 5.6 7.3 8.4 10.5 5.0 2.9 23.5 9.1 5.5 20.2 8.2 5.0 3.6 2.5 7.7 11.6 8.5 6.6 2.6 6.0 5.1 6.1 4.2 11.8 10.0 18.5 7.5 5.8 0.0 5.3 0.0 2.5 12.5 6.2 0.0 2.8 10.1 10.1 3.1 12.1 7.7 13.2 5.3 6.8 2.2 9.5 6.2 16.8 13.8 6.4 13.1 5.1 4.9 10.0 6.1 5.7 0.0 5.1 3.9 6.1 5.3 8.0 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SDHC "CYB560, cybL, PGL3" ENSG00000143252 "Succinate dehydrogenase complex subunit C" Q99643 1 161314381-161363206 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 776.7;Proximal tubular cells: 916.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.48e-2)" "unprognostic (6.88e-2)" "unprognostic (6.38e-3)" "unprognostic (1.86e-2)" "unprognostic (1.90e-2)" "unprognostic (5.02e-2)" "unprognostic (7.08e-2)" "unprognostic (2.33e-1)" "unprognostic (7.38e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.20e-4)" "unprognostic (9.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.19e-3)" "unprognostic (3.77e-1)" 128.9 143.7 73.7 64.1 79.7 60.5 100.3 84.5 85.1 78.7 92.9 118.9 127.8 70.9 76.0 109.7 98.6 63.3 154.1 68.4 83.4 285.7 319.4 65.5 74.7 78.8 79.1 69.2 62.5 173.6 52.4 73.1 76.7 77.3 132.2 84.3 74.8 84.7 277.4 69.8 101.4 101.4 85.1 62.8 89.9 52.7 84.8 93.1 89.5 288.4 105.1 88.4 61.3 85.6 161.1 129.7 157.5 147.7 248.3 213.3 196.3 150.9 190.3 180.3 137.3 185.4 208.7 53.7 190.6 214.8 121.6 178.5 244.3 214.2 193.2 185.6 205.6 110.2 106.6 196.7 126.9 193.8 109.1 211.5 181.7 174.3 119.4 167.9 177.5 164.0 178.9 43.8 266.3 167.0 152.4 112.5 145.4 376.3 123.7 131.6 151.0 217.1 330.3 167.8 118.3 180.7 211.0 385.1 225.4 207.9 342.1 259.3 133.5 103.7 125.1 127.9 147.3 173.3 287.8 269.4 140.3 139.2 193.6 88.6 111.0 65.7 76.6 99.6 79.6 68.6 66.2 75.4 136.1 65.7 71.2 71.0 52.0 66.9 87.5 100.6 78.3 130.0 73.7 79.7 84.5 85.1 68.4 83.4 78.8 79.1 76.7 85.1 84.8 85.6 50.9 44.8 59.4 14.7 70.1 61.8 151.2 342.6 59.7 74.9 81.4 58.3 94.0 131.5 163.5 150.8 64.6 248.0 65.5 95.9 776.7 218.4 18.6 87.1 63.8 80.7 66.8 81.4 19.3 145.2 248.5 79.8 79.5 62.6 58.3 66.6 83.2 249.1 237.3 72.3 27.4 103.4 215.7 100.6 74.4 34.7 102.9 94.6 129.9 9.4 176.1 107.8 107.1 17.6 24.5 142.7 89.5 109.1 71.9 100.2 139.1 916.5 177.9 69.3 52.6 74.5 94.4 115.3 114.4 111.2 76.4 307.6 72.0 215.7 154.2 155.0 SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 530.2;Proximal tubular cells: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" 117.5 95.7 60.0 84.5 63.1 72.9 102.6 68.6 76.3 92.5 65.1 185.2 208.1 88.2 96.7 126.7 92.6 85.6 254.7 60.1 65.4 319.9 391.8 79.3 131.7 63.4 62.5 91.6 77.8 152.4 37.0 95.0 63.2 87.9 190.8 37.4 112.6 100.9 354.7 64.3 175.6 98.1 64.7 85.1 101.1 34.1 63.7 102.5 136.8 449.6 124.8 117.9 76.4 68.2 84.0 67.3 58.1 89.4 212.0 170.7 97.3 97.5 147.6 106.8 132.2 244.8 222.1 155.5 288.4 131.0 156.1 203.5 175.4 139.8 129.8 129.9 92.4 142.8 51.9 140.1 165.6 222.4 107.5 189.6 160.2 110.5 189.1 124.6 153.0 109.6 156.0 208.7 135.0 95.2 143.9 215.0 77.4 333.8 211.6 126.2 145.8 294.4 221.6 175.2 83.5 55.8 135.3 194.8 107.0 81.8 198.9 164.2 108.0 103.8 132.3 114.7 95.0 59.1 73.2 270.7 58.8 297.0 100.5 233.7 293.3 208.8 158.4 390.1 173.1 235.2 170.8 168.8 308.7 198.1 204.3 191.8 257.5 207.9 322.9 151.7 189.9 348.9 60.0 63.1 68.6 76.3 60.1 65.4 63.4 62.5 63.2 64.7 63.7 68.2 104.3 80.1 51.1 12.4 78.0 81.6 102.2 262.2 83.6 12.2 61.0 78.4 216.5 120.1 108.1 90.1 8.4 154.3 55.2 203.8 530.2 82.9 9.9 41.6 67.6 76.4 50.4 70.2 9.6 58.9 124.1 104.6 75.4 41.2 65.9 32.3 76.8 169.7 162.9 11.8 11.2 129.1 154.6 97.1 74.4 37.0 104.1 94.2 76.5 9.4 118.6 52.9 75.2 8.0 9.7 54.1 134.2 99.6 80.9 61.6 253.1 449.9 60.5 18.9 92.1 78.3 110.7 70.4 55.8 127.1 74.4 179.0 71.4 86.2 176.0 98.6 SEC14L5 "KIAA0420, PRELID4B" ENSG00000103184 "SEC14 like lipid binding 5" O43304 16 4958330-5019157 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 78.7" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 85.5;Excitatory neurons: 67.0;Oligodendrocytes: 189.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.5;RPMI-8226: 1.6;SCLC-21H: 2.5;T-47d: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041492, HPA041825" Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "HPA041492: AB_10794519, HPA041825: AB_10794526" "unprognostic (1.90e-3)" "unprognostic (4.08e-2)" "unprognostic (5.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (5.68e-2)" "unprognostic (7.33e-3)" "unprognostic (8.71e-4)" "unprognostic (6.87e-2)" "unprognostic (1.56e-4)" "unprognostic (1.01e-3)" "unprognostic (7.12e-2)" "unprognostic (1.07e-1)" "unprognostic (5.61e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" 0.4 0.5 12.5 0.3 43.6 0.4 0.3 25.9 29.8 0.9 0.0 0.5 0.3 0.1 0.2 0.6 0.7 0.2 5.1 15.4 17.8 0.2 0.1 0.2 0.3 33.4 35.9 0.4 0.6 0.0 2.2 0.3 29.9 0.4 0.6 3.9 0.6 0.2 5.6 1.0 0.2 0.1 22.9 0.3 1.4 0.4 31.5 0.4 0.1 10.9 0.5 0.2 0.4 78.7 0.0 0.1 0.1 0.1 0.2 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.3 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.1 0.0 0.1 1.6 0.0 0.0 2.5 0.0 0.1 0.1 0.1 0.2 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 12.5 43.6 25.9 29.8 15.4 17.8 33.4 35.9 29.9 22.9 31.5 78.7 0.2 0.0 0.0 2.3 0.0 0.3 0.1 0.0 0.0 4.1 0.2 0.1 9.1 1.5 0.1 0.0 85.5 1.1 1.3 0.3 0.0 0.1 1.6 1.0 0.1 0.3 0.0 0.0 67.0 0.2 0.1 0.6 0.0 0.1 0.0 1.5 0.4 0.3 0.3 5.0 7.1 0.6 4.1 0.0 0.3 0.5 0.3 2.0 0.0 1.9 0.5 0.0 0.0 3.5 189.4 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.5 1.9 0.0 0.7 0.2 0.1 0.3 0.0 0.1 0.3 0.0 0.1 0.6 0.0 SELENBP1 "hSBP, hSP56, LPSB" ENSG00000143416 "Selenium binding protein 1" Q13228 1 151364304-151372707 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 509.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 525.6;Distal enterocytes: 1056.9;Erythroid cells: 590.9;Hepatocytes: 501.5;Paneth cells: 451.4;Undifferentiated cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.4" "Lineage enhanced" "Detected in single" "dendritic cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 144.9;HEL: 120.5;HSkMC: 75.9;OE19: 92.8;SK-BR-3: 274.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005741, CAB008366, HPA011731" Enhanced Supported Nucleoli NA NA 59000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "CAB008366: AB_592677, HPA005741: AB_1856662, HPA011731: AB_1856663" "unprognostic (1.51e-1)" "unprognostic (7.01e-2)" "unprognostic (8.52e-3)" "unprognostic (6.25e-3)" "unprognostic (6.28e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.08e-2)" "unprognostic (1.21e-2)" "unprognostic (3.78e-3)" "unprognostic (2.86e-1)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (2.67e-2)" "unprognostic (6.98e-2)" "unprognostic (1.95e-1)" "unprognostic (1.86e-2)" "unprognostic (6.86e-3)" 128.3 18.7 49.8 24.9 53.0 95.9 76.3 45.5 54.8 57.0 47.4 509.3 74.7 31.3 43.4 31.8 132.7 52.2 69.1 47.1 48.2 77.2 261.7 181.0 10.9 47.8 51.0 49.4 29.0 11.9 15.0 20.4 46.5 44.2 471.7 3.9 61.6 48.8 72.9 25.2 94.2 49.5 46.9 51.1 126.4 6.1 51.0 7.1 115.1 138.1 6.8 58.3 29.3 45.7 0.0 17.2 31.9 1.8 144.9 59.1 8.4 5.9 2.6 3.1 6.5 18.1 5.4 0.0 30.7 10.7 0.0 0.4 0.0 0.4 2.8 0.1 14.8 120.5 53.1 28.9 30.5 0.2 0.0 75.9 1.0 5.3 0.1 0.4 19.0 0.0 12.4 0.0 8.0 13.2 0.0 0.0 26.6 92.8 32.2 0.1 1.7 0.7 7.1 0.0 0.4 0.7 0.5 274.4 0.0 25.1 49.4 1.8 1.8 0.0 1.1 16.8 0.1 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 49.8 53.0 45.5 54.8 47.1 48.2 47.8 51.0 46.5 46.9 51.0 45.7 36.6 294.9 525.6 38.2 4.0 10.8 27.7 56.4 30.7 0.3 73.0 59.9 135.7 75.8 123.9 5.5 0.0 2.4 1.9 1056.9 115.4 17.1 0.7 30.9 14.9 27.5 155.0 590.9 0.1 9.1 2.1 85.2 163.6 14.1 27.3 10.9 26.0 501.5 15.3 0.0 0.1 137.2 79.3 39.6 12.4 4.2 66.5 3.9 33.8 13.1 0.2 37.4 0.0 0.0 2.0 6.5 451.4 80.9 0.8 25.6 251.0 148.3 101.5 1.4 52.6 15.6 102.3 0.1 0.3 22.7 9.9 4.0 5.7 30.5 452.4 71.0 SELENOW "SELW, SEPW1" ENSG00000178980 "Selenoprotein W" P63302 19 47778585-47784686 "Predicted intracellular proteins" Antioxidant "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1609.8;skeletal muscle: 1723.7;tongue: 1969.8" "Cell type enhanced" "Detected in many" "Adipocytes: 855.4;Breast myoepithelial cells: 490.5;Distal tubular cells: 633.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 541.5;HUVEC TERT2: 624.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.03e-1)" "unprognostic (8.98e-3)" "unprognostic (7.21e-2)" "unprognostic (2.98e-2)" "unprognostic (6.28e-2)" "unprognostic (4.17e-2)" "unprognostic (4.46e-3)" "prognostic favorable (5.44e-4)" "unprognostic (1.73e-1)" "unprognostic (2.42e-1)" "unprognostic (1.36e-1)" "unprognostic (6.78e-2)" "unprognostic (1.45e-3)" "unprognostic (4.58e-2)" "unprognostic (1.36e-1)" "unprognostic (3.46e-2)" "unprognostic (3.27e-1)" 188.5 103.4 1283.6 107.6 1308.6 44.7 204.0 1297.0 1609.8 270.1 1374.7 535.1 127.4 218.5 258.8 266.6 306.9 240.5 988.8 1351.6 1261.2 146.6 109.6 199.7 112.1 1273.2 1296.9 170.9 132.6 168.7 138.6 153.5 1251.5 233.2 224.7 128.1 195.8 291.5 1723.7 312.3 177.5 467.0 1278.9 146.1 207.8 55.3 1333.8 113.7 156.7 1969.8 87.8 323.5 173.3 1321.9 74.4 119.6 174.0 141.4 124.7 268.1 43.7 76.7 59.6 71.4 53.8 49.6 57.1 0.0 64.3 163.1 70.1 57.8 293.6 389.6 124.1 216.4 72.9 34.9 61.7 63.2 138.0 9.1 131.8 285.1 541.5 119.4 113.0 158.7 624.7 109.1 46.4 28.6 317.7 179.0 156.6 115.4 68.0 186.0 91.4 26.9 18.3 23.5 208.0 130.8 72.4 51.5 77.6 203.0 77.9 299.2 114.2 43.7 213.9 71.0 151.2 50.7 141.3 46.3 153.1 16.1 75.3 93.2 165.0 309.3 187.8 448.3 303.8 226.2 265.1 182.4 333.6 311.7 147.8 159.2 331.0 288.3 19.9 216.1 293.5 166.8 436.6 414.1 1283.6 1308.6 1297.0 1609.8 1351.6 1261.2 1273.2 1296.9 1251.5 1278.9 1333.8 1321.9 855.4 333.3 282.3 0.0 20.4 0.0 0.0 0.0 0.0 0.0 347.1 490.5 0.0 0.0 219.7 154.5 0.0 157.0 127.3 0.0 633.9 278.3 0.0 350.2 221.5 220.8 0.0 0.0 0.0 244.5 327.9 145.5 0.0 188.4 119.8 153.8 0.0 0.0 251.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.3 0.0 0.0 156.6 0.0 0.0 0.0 0.0 243.7 0.0 0.0 21.3 0.0 0.0 380.8 303.9 0.0 0.0 0.0 210.7 0.0 0.0 0.0 0.0 182.4 66.9 341.7 0.0 0.0 SEPTIN5 "H5, HCDCREL-1, PNUTL1, SEPT5" ENSG00000184702 "Septin 5" Q99719 22 19714503-19724224 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 321.9" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 3.4;Smooth muscle cells: 2.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 32 "eosinophil: 15.4;neutrophil: 5.8" "Lineage enriched" "Detected in single" 47 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "K-562: 281.6;THP-1: 75.9" "CAB016120, HPA029095, HPA063885" Enhanced Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 860000 "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Actin filaments, Cytosol" "CAB016120: AB_628240, HPA029095: AB_2672904, HPA063885: AB_2685141" "unprognostic (4.07e-2)" "unprognostic (1.47e-1)" "unprognostic (6.78e-3)" "unprognostic (1.39e-2)" "unprognostic (3.92e-1)" "unprognostic (1.86e-1)" "unprognostic (2.50e-2)" "unprognostic (3.77e-1)" "unprognostic (5.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.88e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.87e-6)" "unprognostic (3.39e-2)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" "unprognostic (3.30e-2)" 17.7 17.7 152.8 5.7 215.6 41.0 16.4 49.2 321.9 54.1 61.9 19.8 5.2 28.1 46.2 62.1 38.8 14.7 165.4 233.6 49.3 12.7 5.2 17.4 8.4 40.9 45.2 29.3 17.0 127.3 82.7 12.0 39.4 20.1 6.3 30.3 15.9 9.9 10.8 126.5 8.8 17.3 24.7 14.3 16.3 29.1 73.1 15.9 33.4 16.2 8.1 13.5 42.8 168.6 0.4 10.6 42.0 64.0 3.9 13.1 0.3 15.8 20.1 17.9 10.5 0.7 5.6 1.5 6.1 35.8 26.0 6.0 30.2 6.0 8.8 9.6 3.4 0.7 2.4 0.2 16.2 0.8 47.2 17.4 7.4 6.0 2.5 5.1 7.5 23.1 281.6 0.6 28.2 4.2 4.6 31.2 5.4 1.0 10.4 41.4 1.3 7.2 1.3 1.4 62.3 49.2 2.4 3.5 2.8 10.2 17.3 75.9 3.0 46.4 55.6 2.0 3.2 4.5 0.0 0.4 5.8 2.2 15.2 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 5.8 0.0 0.0 0.3 0.0 6.0 152.8 215.6 49.2 321.9 233.6 49.3 40.9 45.2 39.4 24.7 73.1 168.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SERP2 "bA269C23.1, C13orf21" ENSG00000151778 "Stress associated endoplasmic reticulum protein family member 2" Q8N6R1 13 44373665-44397714 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 87.7;choroid plexus: 53.7" "Group enriched" "Detected in many" 11 "Early spermatids: 577.8;Late spermatids: 237.7" "Cancer enhanced" "Detected in many" "glioma: 6.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Lineage enhanced" "Detected in single" "granulocytes: 2.6" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.7;SH-SY5Y: 5.1;U-2197: 4.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA038970: AB_2676296" "unprognostic (6.55e-2)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (2.06e-1)" "unprognostic (9.62e-2)" "unprognostic (1.72e-2)" "unprognostic (2.85e-1)" "unprognostic (3.48e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (1.34e-3)" "unprognostic (1.12e-2)" "prognostic favorable (1.94e-4)" "unprognostic (1.48e-1)" "unprognostic (6.60e-2)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" 1.2 2.0 67.6 1.0 70.7 0.0 2.6 60.7 87.7 2.7 53.7 3.9 2.9 4.0 9.0 0.8 2.3 0.9 18.8 71.5 67.0 3.3 1.2 1.1 1.4 63.4 66.0 4.7 1.7 1.3 8.5 0.3 65.0 3.5 1.1 14.2 1.1 3.8 2.1 0.6 2.0 2.0 61.1 0.4 2.7 27.3 66.7 1.9 1.2 0.4 1.2 2.0 2.0 68.4 0.0 0.0 2.1 0.0 0.3 1.8 0.0 0.4 0.6 2.3 1.5 0.0 0.0 0.0 1.8 1.7 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.4 0.0 0.1 1.9 0.0 0.0 0.3 0.0 1.6 0.0 0.4 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.4 5.1 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 0.1 4.7 0.0 0.0 0.1 0.0 1.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 67.6 70.7 60.7 87.7 71.5 67.0 63.4 66.0 65.0 61.1 66.7 68.4 4.0 0.0 1.5 19.6 0.1 1.8 3.7 1.9 4.6 21.0 12.0 7.2 20.0 4.3 1.0 9.2 14.6 2.5 1.1 2.9 17.6 11.3 577.8 0.7 4.6 3.9 14.4 0.8 34.6 12.9 2.5 10.3 0.5 1.2 17.8 7.8 1.4 6.2 0.2 15.2 29.8 4.0 0.0 0.0 1.1 237.7 13.1 0.7 12.4 9.4 0.6 25.0 1.0 13.0 27.1 6.3 1.7 19.2 0.1 3.4 3.9 8.9 1.3 23.3 26.3 15.1 10.0 8.5 12.5 0.4 1.0 2.1 1.8 4.6 4.4 3.2 SERTM1 C13orf36 ENSG00000180440 "Serine rich and transmembrane domain containing 1" A2A2V5 13 36674020-36697839 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.9;endometrium 1: 23.9;fallopian tube: 35.3" "Group enriched" "Detected in some" 7 "Alveolar cells type 1: 9.6;Bipolar cells: 17.9;Endometrial ciliated cells: 5.7;Excitatory neurons: 10.8;Granulosa cells: 14.2;Inhibitory neurons: 17.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.7" "Region enhanced" "Detected in many" "hippocampal formation: 18.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HAP1: 1.2;HEK 293: 1.4;NTERA-2: 3.6;SH-SY5Y: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054814, HPA070485" Enhanced Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA054814: AB_2682611, HPA070485: AB_2686272" "unprognostic (8.71e-2)" "unprognostic (2.11e-1)" "unprognostic (5.58e-3)" "unprognostic (4.66e-3)" "unprognostic (4.05e-3)" "unprognostic (5.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.63e-2)" "unprognostic (1.00e-8)" "unprognostic (2.51e-2)" "unprognostic (5.60e-2)" "unprognostic (4.44e-2)" 6.2 1.3 7.3 0.0 6.0 0.0 0.6 0.1 8.1 12.3 0.0 0.2 0.1 23.9 0.7 0.0 35.3 0.0 0.4 18.9 0.0 0.1 0.0 5.4 0.0 0.0 1.7 6.4 0.3 1.3 11.5 0.0 3.6 0.9 0.0 3.3 0.0 0.6 0.0 0.2 0.0 17.1 0.3 0.0 0.4 0.3 0.4 0.0 9.2 0.0 0.0 0.3 6.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 6.0 0.1 8.1 18.9 0.0 0.0 1.7 3.6 0.3 0.4 1.2 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.0 0.0 0.0 10.8 0.0 0.0 1.3 0.0 0.6 0.0 14.2 0.0 0.0 0.0 1.7 17.9 0.0 0.0 0.0 0.4 0.0 0.3 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SETD9 "C5orf35, MGC33648" ENSG00000155542 "SET domain containing 9" Q8NE22 5 56909260-56925532 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.8" "Group enriched" "Detected in many" 7 "Early spermatids: 691.8;Late spermatids: 372.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 4 "granulocytes: 5.2;monocytes: 3.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049936 Approved Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA049936: " "unprognostic (1.13e-1)" "unprognostic (3.89e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (3.14e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-1)" "unprognostic (2.29e-1)" "unprognostic (7.37e-2)" "unprognostic (8.75e-3)" "unprognostic (2.08e-1)" "unprognostic (1.18e-1)" "unprognostic (2.58e-2)" "unprognostic (1.49e-1)" "unprognostic (3.10e-1)" "unprognostic (1.06e-1)" 5.1 2.8 0.9 1.0 1.1 2.6 5.1 1.1 1.4 1.6 0.9 5.9 5.2 3.0 3.9 3.0 2.3 2.6 5.9 0.8 1.1 6.2 9.9 2.1 2.7 1.3 1.0 3.1 4.4 3.5 0.6 2.4 1.2 2.3 4.6 1.1 6.3 1.2 3.7 1.4 6.7 2.8 1.1 1.8 3.1 18.8 1.0 1.2 4.9 7.2 2.9 2.9 0.9 1.5 6.8 1.6 5.9 3.3 5.1 3.7 3.9 4.8 3.1 5.2 7.2 4.9 5.1 4.5 10.3 5.1 8.1 6.4 3.9 2.6 7.3 4.1 6.9 0.7 1.7 6.6 5.1 3.6 4.7 3.6 3.8 8.7 7.3 4.8 7.8 2.3 5.1 3.1 8.0 11.0 0.5 3.5 7.0 0.0 8.1 5.9 2.2 8.0 5.8 3.0 4.5 6.7 1.1 3.4 10.3 3.7 8.3 4.1 6.1 2.9 9.2 5.0 6.0 4.0 12.8 9.1 3.5 2.5 0.7 5.2 1.0 1.9 0.4 0.9 0.7 0.2 0.8 0.2 0.6 0.3 0.3 0.6 1.8 0.6 3.2 0.2 0.9 0.4 0.9 1.1 1.1 1.4 0.8 1.1 1.3 1.0 1.2 1.1 1.0 1.5 10.7 3.2 2.7 1.0 7.8 17.5 15.6 17.9 1.8 2.8 32.2 30.5 14.7 12.8 9.0 7.3 0.0 15.5 7.6 24.5 56.7 14.6 691.8 10.4 7.7 9.6 18.5 5.2 0.7 17.4 21.4 12.2 9.2 7.6 14.7 7.1 8.2 27.4 14.8 0.0 1.4 10.4 14.2 13.5 35.4 372.2 10.2 11.9 28.4 2.8 13.6 6.9 8.2 2.0 8.6 9.8 20.7 5.7 9.0 28.4 24.7 52.7 9.9 3.1 0.0 14.5 12.7 67.0 13.5 4.8 15.3 14.4 6.8 10.3 14.3 19.2 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 299.3;choroid plexus: 509.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 710.9;Breast myoepithelial cells: 1158.6;Cardiomyocytes: 266.3;Leydig cells: 578.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 3203.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" Yes No 1300000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: AB_2685376" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" 88.4 12.9 9.2 10.5 12.7 1.4 299.3 18.2 15.0 203.7 509.2 24.5 12.2 132.5 1.8 26.1 98.5 61.3 124.8 29.4 8.5 115.3 6.1 4.7 4.0 29.9 10.5 46.8 6.2 1.4 1.2 19.5 29.7 42.6 30.1 2.2 236.9 102.3 2.6 55.4 18.9 82.9 7.7 21.4 24.4 28.4 10.8 3.1 12.7 32.8 3.2 44.9 95.6 24.7 0.1 29.0 75.9 1.9 67.5 3.9 14.5 132.9 694.5 197.9 187.2 0.0 17.8 0.0 0.6 0.7 15.8 0.9 10.8 53.7 277.6 0.0 2.3 0.0 0.0 0.0 6.4 0.0 0.7 11.8 255.9 19.9 19.3 3203.5 6.2 0.2 0.0 0.0 3.7 0.0 0.0 0.2 205.8 0.1 0.3 0.0 15.7 0.0 422.6 0.0 4.1 18.5 5.5 0.0 41.5 264.7 0.1 2.1 1.9 0.1 19.6 0.2 18.3 0.0 0.0 0.0 0.2 0.0 279.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.7 18.2 15.0 29.4 8.5 29.9 10.5 29.7 7.7 10.8 24.7 8.4 0.0 0.0 2.0 1.2 11.2 134.0 1.4 147.4 1.8 710.9 1158.6 266.3 0.0 0.7 62.5 2.1 2.2 9.1 0.0 80.3 4.4 5.0 3.0 131.6 21.0 0.0 0.0 0.2 0.0 82.0 229.5 16.8 3.4 0.0 19.3 53.6 0.3 2.0 1.7 12.1 0.0 0.0 0.3 4.0 25.7 578.4 4.0 99.6 0.0 0.0 76.2 0.0 7.5 20.6 0.1 0.0 130.1 2.1 29.7 0.0 3.2 0.0 1.8 0.0 34.9 18.0 2.3 16.8 53.7 5.5 0.8 7.3 72.6 0.0 9.3 SGCG "A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE" ENSG00000102683 "Sarcoglycan gamma" Q13326 13 23180979-23325162 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 118.8;skeletal muscle: 158.0;tongue: 144.1" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 134.3" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 4 "cerebral cortex: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 66.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA007476 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA007476: AB_1079946" "unprognostic (5.19e-2)" "unprognostic (8.28e-2)" "unprognostic (5.15e-3)" "unprognostic (1.64e-4)" "unprognostic (3.00e-3)" "unprognostic (3.61e-2)" "unprognostic (8.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.29e-1)" "unprognostic (4.49e-1)" "unprognostic (6.05e-2)" "unprognostic (2.23e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (2.98e-3)" "unprognostic (1.07e-1)" 14.3 0.6 0.0 0.1 0.1 0.0 2.2 0.0 1.9 0.4 0.0 1.1 0.1 0.1 8.0 3.3 1.1 0.8 118.8 0.1 0.0 0.3 0.0 4.8 0.0 0.3 0.0 0.2 0.1 2.1 0.3 0.0 0.2 3.2 0.6 0.3 4.3 0.4 158.0 3.4 0.6 0.1 0.0 0.1 0.9 1.5 0.2 0.1 0.1 144.1 0.1 3.0 1.4 0.4 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 66.6 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.2 0.0 0.2 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.3 0.0 0.2 0.0 0.2 0.4 0.2 0.0 0.0 0.3 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 1.3 0.0 0.0 12.5 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 1.6 0.0 0.0 0.0 3.4 3.0 7.5 0.2 5.4 1.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 1.2 3.8 13.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 SGSM1 "KIAA1941, RUTBC2" ENSG00000167037 "Small G protein signaling modulator 1" Q2NKQ1 22 24806169-24927578 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.5;heart muscle: 11.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 97.0;Inhibitory neurons: 76.4;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 58.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 2.9;RPMI-8226: 2.2;SCLC-21H: 2.0;SH-SY5Y: 1.3;U-266/84: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003986 Approved NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA003986: AB_1856513" "unprognostic (6.66e-2)" "unprognostic (1.51e-1)" "unprognostic (1.97e-2)" "unprognostic (1.40e-4)" "unprognostic (4.79e-3)" "unprognostic (6.43e-2)" "unprognostic (1.39e-3)" "unprognostic (1.13e-2)" "unprognostic (1.02e-1)" "unprognostic (5.50e-2)" "unprognostic (2.23e-3)" "unprognostic (1.37e-1)" "unprognostic (2.61e-6)" "unprognostic (1.46e-1)" "unprognostic (4.66e-1)" "unprognostic (2.25e-2)" "unprognostic (3.93e-2)" 0.5 3.3 12.5 0.4 11.5 0.2 0.9 6.8 12.9 1.2 4.3 2.0 0.4 0.6 1.0 0.3 4.7 0.6 11.5 10.1 20.5 1.8 0.1 1.1 0.4 11.2 15.4 1.8 3.6 7.8 10.5 0.3 19.0 1.6 1.6 1.5 1.3 0.8 0.6 3.2 0.9 0.5 7.5 0.3 2.9 1.8 18.2 0.3 2.1 0.2 0.3 1.7 1.1 9.4 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 2.9 0.3 0.0 0.0 2.2 0.0 0.3 2.0 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.1 12.5 11.5 6.8 12.9 10.1 20.5 11.2 15.4 19.0 7.5 18.2 9.4 1.4 3.2 6.9 2.6 0.7 3.8 9.8 0.1 2.2 3.2 1.5 1.9 26.4 1.5 1.5 5.5 4.2 0.3 3.2 3.1 3.9 1.7 0.5 10.3 0.9 3.7 17.3 0.0 97.0 1.9 0.1 4.5 7.1 6.6 1.3 0.1 11.4 0.1 1.9 1.7 76.4 6.4 0.0 0.3 8.4 0.5 0.3 0.8 10.6 12.2 0.1 2.1 5.2 33.7 58.6 1.3 5.4 0.4 0.5 5.6 0.5 0.7 1.5 1.5 13.1 3.1 2.5 1.2 7.9 0.4 3.8 0.3 2.3 0.3 4.8 4.8 SHISA4 "C1orf40, hShisa4, TMEM58" ENSG00000198892 "Shisa family member 4" Q96DD7 1 201888680-201892587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;skeletal muscle: 219.7" "Cell type enhanced" "Detected in many" "Muller glia cells: 37.5" "Cancer enhanced" "Detected in all" "glioma: 49.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 24.6;intermediate monocyte: 8.1;neutrophil: 9.1;non-classical monocyte: 10.2" "Group enriched" "Detected in many" 10 "granulocytes: 24.6;monocytes: 10.2" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 23.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061273, HPA067885" Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA061273: AB_2684460, HPA067885: " "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (1.48e-3)" "unprognostic (2.12e-3)" "unprognostic (6.59e-2)" "unprognostic (8.29e-3)" "unprognostic (7.06e-2)" "unprognostic (5.00e-2)" "unprognostic (2.32e-1)" "unprognostic (1.44e-1)" "unprognostic (8.29e-2)" "unprognostic (2.32e-2)" "unprognostic (1.63e-3)" "unprognostic (1.20e-1)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-1)" 6.7 26.9 64.6 2.0 71.6 0.5 5.9 61.5 59.4 9.2 27.3 7.7 0.4 10.9 3.5 2.7 6.9 3.6 48.6 55.5 53.3 6.4 3.2 5.2 0.8 63.9 64.9 10.7 5.1 3.9 9.2 2.3 58.0 8.5 0.9 4.7 15.7 4.0 219.7 3.6 3.5 3.7 59.1 2.8 6.7 5.7 68.4 0.3 11.4 58.3 0.6 8.6 6.4 57.1 1.3 10.5 1.6 7.8 12.7 7.7 1.3 9.1 19.3 5.2 6.5 2.0 4.1 0.0 10.6 12.6 17.2 3.4 0.1 1.4 3.0 1.3 0.6 0.1 2.8 1.3 8.2 0.1 6.7 7.6 4.3 6.5 3.0 23.2 8.0 0.1 0.2 0.7 8.1 1.3 0.0 0.0 0.8 0.9 11.3 0.4 0.0 2.1 5.0 4.1 0.5 6.6 3.3 1.6 10.9 7.6 4.4 1.0 7.5 6.3 5.5 3.9 4.4 2.4 2.9 0.1 9.2 0.0 11.2 0.0 1.7 24.6 1.7 8.1 0.8 0.0 0.3 0.4 0.9 0.0 0.0 0.3 9.1 0.0 10.2 0.0 0.0 0.7 64.6 71.6 61.5 59.4 55.5 53.3 63.9 64.9 58.0 59.1 68.4 57.1 12.8 0.0 1.7 14.4 0.3 14.1 4.5 7.4 6.8 11.7 8.2 14.4 20.9 8.6 3.7 11.0 4.2 2.0 0.9 0.1 33.2 24.9 0.7 2.4 10.0 11.1 1.8 0.0 8.4 15.4 27.2 19.2 3.6 2.7 1.3 10.4 12.5 12.1 3.2 5.0 6.5 0.1 6.1 6.9 25.1 2.3 15.8 3.7 23.2 1.0 4.6 37.5 0.0 17.6 19.2 9.5 0.0 29.3 0.2 7.4 0.0 6.3 1.3 3.8 19.7 9.2 18.0 1.4 0.8 0.9 6.8 2.7 1.5 2.3 0.1 2.1 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 104.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 58.0;Cardiomyocytes: 59.5;Distal enterocytes: 102.4;Paneth cells: 53.0;Proximal enterocytes: 51.6;Undifferentiated cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 88.6;ASC TERT1: 91.3;HSkMC: 98.9;OE19: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" NA NA 2200000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 18.7 17.3 16.8 11.8 21.6 3.7 15.9 26.9 19.8 13.0 38.9 97.8 34.3 7.1 34.3 13.6 19.3 16.7 43.8 16.1 27.1 62.1 43.4 20.6 5.8 25.3 23.7 5.7 17.3 45.3 14.4 11.8 24.7 20.4 104.4 6.2 18.4 15.3 26.7 13.0 35.8 10.4 23.0 9.1 19.0 10.3 24.9 3.7 54.0 33.3 6.7 16.8 7.8 26.3 8.9 14.0 8.0 34.6 88.6 91.3 20.9 16.8 24.0 4.3 2.6 10.9 61.4 5.5 24.2 21.5 9.4 17.3 12.8 18.7 4.2 26.0 3.9 8.6 3.7 11.1 41.8 0.7 7.2 98.9 24.9 11.4 17.3 58.5 30.6 11.0 7.1 37.5 14.8 16.5 0.2 0.6 5.0 97.7 28.5 3.2 0.2 8.4 51.4 12.1 2.4 5.1 46.5 18.6 8.0 24.0 36.8 3.2 34.1 23.6 4.3 26.5 4.0 9.4 7.5 0.7 8.3 4.6 9.8 7.6 2.9 0.1 0.4 2.1 0.3 0.5 1.3 0.6 1.9 0.7 1.7 1.1 0.5 0.2 3.7 0.5 0.6 1.8 16.8 21.6 26.9 19.8 16.1 27.1 25.3 23.7 24.7 23.0 24.9 26.3 4.2 19.2 58.0 11.8 2.4 3.2 6.3 6.7 7.4 6.5 10.1 4.3 59.5 12.8 9.4 36.8 0.0 7.6 0.6 102.4 9.8 15.2 14.0 9.1 9.3 6.9 14.5 5.2 15.0 3.8 8.8 7.5 12.8 14.0 1.3 3.9 8.9 30.0 4.5 5.0 9.1 31.0 4.1 3.5 1.6 12.0 3.1 4.3 3.6 6.5 4.5 1.9 1.0 8.0 6.7 5.2 53.0 1.2 3.9 7.4 51.6 26.2 11.9 1.8 0.0 4.9 7.9 14.8 9.6 12.2 5.3 6.7 2.0 8.9 63.6 7.1 SIRT3 SIR2L3 ENSG00000142082 "Sirtuin 3" Q9NTG7 11 215030-236931 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026809, CAB037142" Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "CAB037142: AB_1079982, HPA026809: AB_10601160" "unprognostic (1.76e-2)" "unprognostic (2.69e-1)" "unprognostic (2.04e-1)" "prognostic favorable (8.51e-5)" "unprognostic (1.52e-3)" "unprognostic (2.65e-1)" "unprognostic (3.45e-2)" "unprognostic (5.52e-2)" "unprognostic (8.64e-2)" "unprognostic (1.31e-1)" "prognostic favorable (4.45e-4)" "unprognostic (2.06e-1)" "prognostic favorable (4.85e-9)" "unprognostic (1.04e-1)" "unprognostic (5.53e-2)" "unprognostic (3.45e-1)" "unprognostic (3.75e-2)" 11.1 13.8 24.5 10.4 28.8 11.8 18.6 19.7 28.8 14.3 26.1 13.9 13.3 12.6 40.1 9.9 14.4 7.6 24.4 25.1 20.8 17.2 25.8 10.3 13.8 19.0 20.4 18.3 18.0 11.2 28.0 5.8 18.4 16.7 14.2 26.8 12.6 12.4 27.3 20.2 14.6 9.7 19.0 14.7 13.5 25.2 21.6 6.8 15.7 19.9 14.9 11.5 11.1 24.0 9.7 11.1 16.7 17.7 19.1 24.1 8.0 13.6 11.0 10.1 7.9 11.5 22.8 5.9 6.2 8.5 9.8 18.6 8.2 7.4 9.8 11.2 12.7 7.4 15.7 12.6 8.4 9.7 17.3 17.8 14.1 10.2 10.9 17.3 6.7 11.1 15.3 11.0 4.6 10.8 4.0 15.0 7.5 8.5 13.2 10.8 13.2 9.8 10.2 6.6 9.3 7.5 11.5 16.7 6.4 10.8 11.9 2.2 9.3 11.4 5.4 3.2 4.1 19.4 17.3 8.4 12.4 7.7 5.9 0.1 3.1 3.1 3.6 2.5 3.8 5.3 3.3 4.1 2.8 4.3 6.0 4.9 3.1 8.1 6.6 4.8 4.0 2.7 24.5 28.8 19.7 28.8 25.1 20.8 19.0 20.4 18.4 19.0 21.6 24.0 6.0 3.2 6.5 17.0 10.4 5.0 7.0 13.1 12.5 7.4 16.0 15.5 23.4 14.3 7.4 5.5 8.4 12.6 7.2 7.2 33.2 7.5 22.0 7.4 5.8 6.7 6.0 14.3 19.2 5.8 10.3 8.6 11.7 4.6 10.2 8.4 7.5 18.3 8.8 10.1 18.3 8.1 10.2 5.5 3.3 21.0 9.0 6.4 10.6 8.4 3.5 13.5 5.2 9.0 11.6 5.1 9.3 9.1 14.6 5.5 14.3 18.9 9.0 9.5 0.0 7.3 6.5 25.5 9.6 9.9 4.1 6.8 8.4 14.2 11.2 4.0 SIRT4 SIR2L4 ENSG00000089163 "Sirtuin 4" Q9Y6E7 12 120302316-120313249 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage" Transferase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029691, HPA029692" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA029691: AB_10600118, HPA029692: AB_10611520" "unprognostic (2.62e-2)" "unprognostic (7.08e-2)" "unprognostic (4.46e-3)" "unprognostic (1.09e-1)" "unprognostic (1.51e-1)" "unprognostic (2.35e-2)" "unprognostic (2.37e-2)" "unprognostic (4.53e-2)" "unprognostic (1.25e-1)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (1.54e-1)" "prognostic favorable (1.75e-4)" "unprognostic (4.97e-2)" "unprognostic (2.11e-1)" "unprognostic (9.74e-3)" "unprognostic (2.31e-1)" 0.9 3.9 2.9 1.0 2.6 0.3 1.1 3.7 3.2 1.9 3.1 2.8 3.5 2.0 0.8 1.4 1.4 1.2 4.5 2.8 2.5 3.2 3.9 1.6 1.4 2.8 2.5 2.5 1.9 2.8 0.9 0.9 2.8 1.3 1.0 3.7 3.0 1.5 9.8 3.1 1.6 1.8 2.3 1.5 2.2 6.2 2.6 2.2 1.8 7.2 1.0 1.5 1.3 2.9 0.6 1.4 1.9 0.9 5.9 1.9 0.9 1.4 1.6 1.1 2.9 1.5 0.9 1.0 1.6 0.8 1.5 0.3 1.9 0.7 1.9 2.0 2.5 0.0 0.3 1.2 1.4 1.1 0.5 1.7 1.6 0.6 0.4 3.2 1.5 2.8 2.0 0.1 1.7 0.8 1.9 1.6 1.1 0.4 1.1 2.3 3.5 1.0 1.6 0.1 1.9 1.6 1.0 0.1 0.9 3.2 2.3 0.4 0.2 0.9 1.5 0.8 0.3 2.3 2.1 0.3 0.9 0.6 1.4 6.7 1.4 0.2 3.8 0.6 5.8 2.7 2.5 3.1 0.8 3.5 4.4 3.9 0.0 2.5 0.1 3.8 0.2 1.2 2.9 2.6 3.7 3.2 2.8 2.5 2.8 2.5 2.8 2.3 2.6 2.9 1.3 6.4 2.0 3.6 2.3 0.4 0.8 0.6 1.2 0.8 1.3 2.4 4.5 0.0 2.4 0.0 2.1 1.2 2.2 0.1 7.9 1.7 29.7 1.2 1.5 0.4 0.0 0.8 5.5 1.1 1.0 1.2 1.1 1.0 0.0 2.8 0.4 1.4 0.7 5.0 7.0 0.9 0.0 0.0 0.6 4.0 1.2 0.4 0.0 1.0 0.0 1.8 0.0 3.5 2.5 0.6 2.9 2.2 0.7 0.4 4.5 6.1 0.4 2.9 0.0 1.1 1.5 6.3 0.9 1.5 1.4 0.8 1.3 6.3 0.9 0.1 SIRT5 ENSG00000124523 "Sirtuin 5" Q9NXA8 6 13574227-13615158 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.5;Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021798, HPA022002, HPA022992" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA021798: AB_1856911, HPA022002: AB_1856913, HPA022992: AB_1856915" "unprognostic (8.53e-2)" "unprognostic (7.79e-2)" "unprognostic (4.71e-2)" "unprognostic (5.26e-3)" "unprognostic (6.19e-2)" "unprognostic (1.63e-1)" "unprognostic (8.72e-2)" "unprognostic (1.38e-1)" "unprognostic (8.54e-3)" "unprognostic (2.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "prognostic favorable (8.76e-10)" "unprognostic (2.39e-1)" "unprognostic (6.88e-2)" "unprognostic (6.86e-2)" "unprognostic (2.36e-3)" 7.2 6.0 9.4 5.2 10.6 5.8 6.6 10.4 12.2 5.4 13.5 8.1 7.7 6.1 5.6 5.6 9.2 5.2 28.6 10.5 10.6 11.5 33.5 5.4 8.3 9.2 9.6 10.1 6.7 16.2 7.3 5.6 9.9 6.4 8.7 6.1 10.6 6.8 33.4 7.9 9.8 5.9 8.4 9.6 8.2 6.8 10.9 8.2 9.0 38.0 7.2 6.0 5.4 11.1 10.5 8.9 8.1 10.4 5.7 8.9 7.6 5.1 5.3 6.1 8.0 12.9 11.1 14.1 35.7 4.3 10.9 16.9 7.4 11.1 7.6 5.9 10.3 8.5 5.6 20.5 11.0 6.7 6.7 7.8 19.9 4.5 19.9 12.7 10.3 20.3 13.8 4.6 6.5 12.3 8.2 13.2 7.7 16.9 13.7 15.4 4.4 24.4 10.3 11.0 13.7 4.5 4.3 7.9 25.9 25.0 11.6 4.9 8.6 6.6 3.4 4.2 5.8 11.6 15.4 10.7 4.5 7.3 8.4 0.7 6.0 16.7 9.9 9.2 10.7 14.0 13.0 9.5 6.3 12.7 11.8 10.8 2.6 11.8 17.3 5.9 10.7 7.9 9.4 10.6 10.4 12.2 10.5 10.6 9.2 9.6 9.9 8.4 10.9 11.1 16.6 28.9 3.2 30.0 8.2 4.1 11.4 14.9 10.8 7.3 9.7 9.9 52.5 15.7 16.8 11.0 0.0 20.5 6.6 9.4 52.8 13.0 2.9 13.1 5.4 12.3 6.1 15.8 36.6 6.7 10.5 6.7 6.6 8.1 0.0 23.5 9.7 25.7 9.4 1.7 39.2 13.2 8.2 13.9 3.8 2.0 8.1 8.4 5.4 14.0 6.3 11.6 10.3 15.1 25.8 7.2 13.4 5.7 4.7 6.2 18.1 34.1 22.5 7.2 0.0 9.8 6.6 8.5 12.0 9.8 4.5 10.7 7.9 13.2 15.0 9.0 SLC12A7 "DKFZP434F076, KCC4" ENSG00000113504 "Solute carrier family 12 member 7" Q9Y666 5 1050384-1112063 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 77.3" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041652 Approved Uncertain Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA041652: AB_10793971" "unprognostic (2.22e-2)" "unprognostic (1.56e-1)" "unprognostic (8.92e-2)" "unprognostic (2.86e-1)" "unprognostic (1.69e-2)" "unprognostic (8.72e-2)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.67e-1)" "unprognostic (1.71e-3)" "unprognostic (4.40e-2)" "unprognostic (4.50e-2)" "unprognostic (3.44e-2)" "unprognostic (1.65e-3)" "unprognostic (1.17e-3)" "unprognostic (1.26e-1)" "unprognostic (3.93e-2)" "prognostic favorable (3.16e-5)" 21.1 14.6 8.9 7.2 8.0 4.0 18.8 7.2 10.4 15.8 12.3 24.1 24.0 13.8 1.0 8.0 16.6 12.0 77.3 7.9 12.0 45.1 72.4 23.1 5.7 8.0 10.7 12.3 27.6 4.4 20.5 2.9 8.0 20.7 5.4 5.5 18.9 3.0 6.3 15.8 31.9 3.3 6.8 34.9 28.1 29.9 9.4 7.8 24.7 3.1 2.2 14.5 10.8 7.1 3.8 10.0 5.5 17.3 0.8 0.9 8.7 0.2 1.1 0.8 0.0 24.5 6.4 0.0 20.0 0.3 6.8 7.6 4.6 6.1 0.0 23.0 6.1 4.8 13.4 8.6 12.2 0.0 10.4 1.8 0.8 0.0 1.8 0.3 5.5 2.2 7.6 0.2 0.0 12.0 14.8 0.1 11.9 14.4 16.3 43.9 24.0 20.5 6.5 14.8 3.1 3.8 5.6 0.1 6.0 3.3 9.7 2.7 4.8 0.0 5.7 0.0 0.0 0.3 0.0 2.5 0.0 0.6 2.8 0.2 1.8 0.0 1.1 2.7 1.2 0.6 1.1 1.3 2.1 0.6 1.2 1.2 0.0 1.4 3.8 0.9 1.1 1.3 8.9 8.0 7.2 10.4 7.9 12.0 8.0 10.7 8.0 6.8 9.4 7.1 21.3 9.6 15.2 8.5 7.3 7.0 6.3 8.9 6.8 25.3 18.4 13.8 35.8 31.5 13.6 29.5 2.1 0.2 14.2 42.0 1.9 23.5 0.4 40.9 11.0 27.9 13.2 19.1 0.3 18.1 0.4 11.6 39.8 63.4 8.2 16.6 11.7 34.5 19.8 281.0 0.5 19.4 18.3 28.0 19.8 1.9 3.7 29.0 16.0 14.0 9.1 5.2 5.2 1.5 0.0 28.8 35.8 5.7 5.3 15.7 27.3 23.2 23.1 3.6 19.7 5.2 8.4 1.0 3.4 3.5 6.8 0.3 9.8 5.4 19.3 15.2 SLC16A7 MCT2 ENSG00000118596 "Solute carrier family 16 member 7" O60669 12 59596029-59789855 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 34.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Early spermatids: 117.3;Excitatory neurons: 150.5;Inhibitory neurons: 128.2;Late spermatids: 135.5" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 22.2" HPA005911 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA005911: AB_1853659" "unprognostic (1.52e-2)" "unprognostic (9.47e-3)" "unprognostic (9.48e-2)" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (1.29e-2)" "unprognostic (5.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-2)" "unprognostic (9.79e-2)" "prognostic favorable (8.85e-5)" "unprognostic (2.19e-3)" "unprognostic (3.11e-1)" "unprognostic (9.35e-2)" "unprognostic (2.45e-2)" 20.1 6.8 1.2 3.9 1.2 4.7 4.1 5.7 3.9 2.8 3.7 2.0 1.6 3.0 1.5 6.3 2.2 5.4 34.4 1.3 0.3 11.6 3.9 4.5 4.9 2.9 0.4 2.7 9.8 1.0 1.5 1.6 2.9 1.6 2.5 1.8 2.9 1.6 1.8 7.9 2.5 3.5 0.5 6.3 10.0 2.2 1.3 4.5 1.6 3.6 4.2 4.0 3.0 4.2 0.2 3.6 0.8 0.5 10.9 18.1 0.2 8.8 8.1 4.0 3.4 0.3 6.3 5.8 2.5 16.8 3.8 0.8 1.0 1.7 6.0 2.4 0.5 10.7 12.6 0.5 5.9 14.3 0.1 8.5 3.9 1.4 10.3 7.5 1.6 7.2 0.2 13.0 6.5 3.4 5.5 3.2 0.8 1.2 3.3 0.5 0.1 2.7 9.5 16.0 3.0 1.0 0.1 0.4 6.2 0.7 0.5 2.4 0.0 8.6 3.3 15.6 0.5 11.3 0.2 10.0 10.2 0.1 1.6 0.2 1.5 0.0 4.2 3.2 5.6 1.8 3.3 3.6 1.5 4.1 3.5 5.8 0.1 3.0 8.4 2.1 3.8 2.3 1.2 1.2 5.7 3.9 1.3 0.3 2.9 0.4 2.9 0.5 1.3 4.2 15.3 28.9 21.4 13.7 28.4 10.1 7.8 9.9 16.5 24.5 1.5 3.9 135.4 90.1 16.5 46.0 10.4 0.3 29.7 0.8 23.5 53.3 117.3 2.1 25.0 22.0 0.0 2.5 150.5 67.1 0.3 36.2 7.1 9.1 10.1 4.7 9.3 14.5 3.6 8.4 128.2 27.2 6.1 32.7 6.1 135.5 6.8 24.8 3.6 14.0 14.9 1.3 37.0 63.8 82.8 28.0 1.2 10.1 26.3 8.1 1.0 0.7 14.4 6.0 6.6 14.0 18.9 4.2 4.5 61.5 12.6 0.7 35.8 80.1 1.5 3.4 SLC25A10 DIC ENSG00000183048 "Solute carrier family 25 member 10" Q9UBX3 17 81712236-81721016 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 183.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 42.3;Late spermatids: 76.9;Proximal enterocytes: 50.9;Proximal tubular cells: 84.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "Hep G2: 158.9;SK-BR-3: 116.6" HPA023048 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoplasm "HPA023048: AB_2301950" "unprognostic (7.17e-2)" "unprognostic (2.38e-2)" "unprognostic (2.36e-2)" "unprognostic (1.36e-1)" "unprognostic (9.50e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.66e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-2)" "prognostic favorable (8.14e-4)" "unprognostic (6.73e-2)" "unprognostic (1.33e-1)" "unprognostic (6.02e-2)" "unprognostic (6.32e-2)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "prognostic favorable (1.31e-4)" 17.8 14.8 5.3 3.0 5.0 9.5 16.8 5.6 6.2 6.5 6.4 26.1 21.4 3.8 2.7 38.8 9.2 5.5 10.4 4.6 5.2 72.9 183.3 4.3 2.5 6.6 5.2 4.8 35.8 17.3 6.3 1.8 5.1 17.2 6.8 0.6 26.0 6.1 5.8 17.3 20.1 0.9 5.8 4.8 24.0 35.0 5.4 3.9 9.6 1.9 2.9 9.1 11.5 6.6 45.3 81.8 7.6 38.1 2.9 2.3 15.3 19.2 6.1 23.2 17.4 49.5 18.4 20.2 14.3 4.5 11.2 28.3 10.8 19.3 4.2 14.9 66.2 16.7 49.0 158.9 3.3 37.5 19.5 1.6 10.0 16.5 3.2 4.5 13.6 27.9 28.0 24.3 8.2 85.4 54.3 40.0 7.8 18.8 63.9 41.0 16.3 63.6 21.1 39.6 49.8 34.0 18.1 116.6 4.0 2.0 50.3 20.4 6.1 17.9 58.6 26.5 34.4 15.3 8.3 12.0 7.8 39.0 15.9 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.2 0.1 0.0 0.0 1.0 0.0 0.1 0.2 0.2 5.3 5.0 5.6 6.2 4.6 5.2 6.6 5.2 5.1 5.8 5.4 6.6 1.4 0.0 2.2 1.6 1.3 0.0 4.5 0.0 2.2 4.9 14.6 7.5 3.8 17.2 3.1 14.7 0.0 16.4 2.3 10.2 25.4 16.9 30.5 22.3 3.8 1.5 4.9 8.2 1.2 22.9 6.9 2.3 18.8 16.4 0.0 5.1 3.6 42.3 8.0 0.0 1.7 15.3 0.0 2.4 0.0 76.9 2.1 2.0 0.0 0.0 0.8 1.9 3.1 0.5 1.2 9.9 19.3 1.9 4.3 4.7 50.9 84.6 7.3 4.2 0.0 1.3 1.6 27.9 3.1 15.9 0.0 4.2 1.5 5.3 27.2 7.9 SLC25A12 Aralar ENSG00000115840 "Solute carrier family 25 member 12" O75746 2 171783405-171999859 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 97.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.7;Excitatory neurons: 148.5;Inhibitory neurons: 175.2;Oligodendrocyte precursor cells: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035333, HPA035334" Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA 9100 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA035333: AB_10603028, HPA035334: AB_2674577" "unprognostic (3.24e-2)" "unprognostic (2.52e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (2.65e-2)" "unprognostic (7.27e-2)" "unprognostic (4.21e-3)" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (4.96e-2)" "unprognostic (7.76e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.91e-8)" "unprognostic (8.64e-3)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" 11.1 11.5 8.5 4.0 9.0 2.8 11.6 9.3 12.3 11.5 6.1 25.2 2.2 13.4 4.3 12.7 11.7 3.7 62.7 8.9 9.0 13.4 1.8 7.1 4.4 6.9 6.7 14.5 3.9 12.0 17.1 3.2 6.8 13.7 6.1 15.8 16.8 9.5 97.0 14.5 10.7 8.5 5.8 8.9 16.4 6.1 7.4 5.6 15.1 51.1 5.2 16.2 12.4 8.4 4.9 3.0 4.2 8.0 9.5 11.7 0.0 5.3 11.2 7.7 7.3 2.2 3.2 14.5 2.6 7.5 4.3 4.3 7.9 8.5 10.7 6.3 10.4 6.9 4.4 5.5 3.8 14.8 4.9 12.6 7.0 11.0 2.3 4.1 8.0 7.0 5.0 5.2 4.4 3.2 9.7 6.5 3.0 3.8 4.7 9.6 4.7 7.4 8.0 4.5 5.1 1.6 2.6 8.5 4.0 2.5 2.8 3.1 6.4 6.2 2.0 6.0 3.2 8.8 4.2 13.6 9.1 7.5 2.9 0.0 0.4 0.1 1.0 0.4 0.8 0.7 0.5 0.9 0.4 0.5 0.9 1.5 0.0 0.9 0.7 0.1 0.7 0.4 8.5 9.0 9.3 12.3 8.9 9.0 6.9 6.7 6.8 5.8 7.4 8.4 9.8 0.0 9.8 71.2 11.3 6.9 10.2 13.2 19.9 25.5 9.3 11.8 97.7 0.0 18.4 18.4 25.0 7.5 10.7 11.6 19.6 1.7 3.2 5.0 10.3 8.7 14.4 6.9 148.5 3.3 1.8 15.1 12.8 6.1 10.8 7.3 7.9 0.6 4.5 37.0 175.2 6.1 16.2 8.4 5.4 2.1 12.5 7.2 16.0 25.3 9.7 19.8 5.2 111.6 44.1 2.0 4.7 24.5 19.5 4.6 4.1 13.2 11.2 25.5 13.1 12.5 16.6 7.8 9.1 16.8 7.7 1.2 15.0 11.0 7.6 8.3 SLC25A20 "CAC, CACT" ENSG00000178537 "Solute carrier family 25 member 20" O43772 3 48856926-48898904 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.2;Hepatocytes: 64.2;Proximal enterocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 96.1;RPMI-8226: 138.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016862, HPA029863" Approved Approved Mitochondria,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Mitochondria, Cytosol" "HPA016862: AB_1857028, HPA029863: AB_10602893" "unprognostic (1.02e-1)" "unprognostic (1.84e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-2)" "unprognostic (5.18e-2)" "unprognostic (3.97e-2)" "unprognostic (1.03e-1)" "unprognostic (5.96e-3)" "unprognostic (4.06e-1)" "unprognostic (1.73e-1)" "unprognostic (1.36e-2)" "unprognostic (2.51e-1)" "unprognostic (3.71e-3)" "unprognostic (3.34e-1)" "unprognostic (5.12e-1)" "unprognostic (4.22e-2)" "unprognostic (3.49e-2)" 20.7 29.9 16.3 11.9 18.2 10.7 17.9 18.6 16.4 8.3 15.3 26.5 65.6 10.4 4.6 9.1 12.8 15.7 62.8 15.5 17.9 25.6 148.3 15.6 14.6 17.7 17.4 5.9 30.4 17.3 11.6 7.3 17.8 11.7 23.5 4.5 19.9 9.0 66.5 10.4 52.7 15.1 17.4 20.6 21.0 9.1 17.5 17.3 11.4 61.1 16.1 11.3 8.4 18.4 4.1 12.8 9.7 13.8 30.1 11.8 1.9 22.3 11.8 15.2 15.8 16.3 19.1 19.0 15.6 35.1 18.7 4.1 24.5 9.8 11.6 47.9 11.8 26.4 19.2 20.4 14.0 27.8 48.1 14.9 11.2 20.6 3.8 6.1 20.2 28.1 24.1 96.1 20.2 10.9 30.4 13.7 5.1 22.9 27.6 10.6 5.9 138.4 16.4 10.1 3.9 13.6 20.7 0.2 11.4 13.6 30.5 12.9 16.6 17.2 3.2 25.5 16.4 35.6 27.0 21.8 24.5 19.5 23.3 60.8 101.1 215.2 97.4 79.7 62.2 36.8 53.1 71.2 97.5 33.0 41.2 69.1 48.6 64.6 83.7 120.5 60.7 112.3 16.3 18.2 18.6 16.4 15.5 17.9 17.7 17.4 17.8 17.4 17.5 18.4 7.5 6.4 2.7 13.1 7.0 1.8 2.5 4.6 3.4 1.1 4.0 3.6 42.2 4.3 4.4 0.0 6.2 2.3 13.6 28.4 3.9 3.5 1.3 2.3 4.6 5.5 7.3 16.4 2.2 4.3 2.3 6.1 9.2 2.1 1.3 3.8 7.5 64.2 16.9 0.0 3.8 12.7 2.0 13.4 4.5 1.8 10.5 10.0 1.8 1.0 31.3 2.9 32.0 1.0 6.0 3.7 16.4 12.4 12.6 3.9 51.8 16.7 5.9 1.3 0.0 5.4 5.3 8.3 7.1 4.1 1.3 1.2 14.4 27.7 16.6 2.9 SLC25A30 ENSG00000174032 "Solute carrier family 25 member 30" Q5SVS4 13 45393316-45418455 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 71.6;skeletal muscle: 86.3;tongue: 63.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 38.8;Hepatocytes: 43.6;Proximal tubular cells: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045260 Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA045260: AB_10962505" "unprognostic (9.23e-2)" "unprognostic (9.92e-2)" "unprognostic (1.05e-1)" "unprognostic (4.28e-2)" "unprognostic (1.96e-1)" "unprognostic (2.63e-1)" "unprognostic (1.35e-2)" "unprognostic (3.16e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (5.69e-2)" "unprognostic (1.58e-1)" "prognostic favorable (9.91e-8)" "unprognostic (2.24e-1)" "unprognostic (5.19e-2)" "unprognostic (4.12e-1)" "unprognostic (6.19e-3)" 9.5 9.9 5.2 6.0 6.2 10.5 8.4 5.1 6.0 9.7 8.6 5.6 4.3 9.1 6.8 7.0 6.5 7.5 71.6 4.7 6.5 41.9 32.2 7.7 8.3 5.6 5.4 18.5 5.5 5.1 4.3 4.3 6.0 13.6 6.0 1.6 8.2 12.7 86.3 5.9 4.4 10.1 5.3 11.5 5.1 6.1 5.6 5.1 11.4 63.3 7.9 6.3 6.2 5.4 3.9 8.4 5.0 21.4 24.4 15.5 1.7 18.2 10.5 15.3 9.2 8.8 10.4 0.0 15.5 18.6 11.4 7.4 11.6 18.2 18.1 12.8 9.4 14.6 5.5 23.8 14.4 20.9 18.9 10.1 12.1 22.6 16.7 18.0 26.9 14.3 8.9 0.0 31.3 4.6 7.7 14.6 7.3 4.5 10.7 19.1 8.3 7.8 33.3 3.2 1.0 5.0 10.2 16.1 14.7 8.6 12.0 28.0 10.0 14.2 8.0 16.0 12.6 3.7 8.0 0.3 15.6 19.5 22.3 0.0 1.2 1.9 0.8 1.3 0.6 0.6 0.9 0.9 1.7 0.6 1.0 0.4 0.0 0.7 0.6 2.2 0.3 0.5 5.2 6.2 5.1 6.0 4.7 6.5 5.6 5.4 6.0 5.3 5.6 5.4 6.2 6.4 2.2 4.2 4.5 12.9 2.0 4.2 1.2 1.9 8.6 4.4 38.8 8.6 2.5 14.7 4.2 0.8 5.6 1.6 23.5 3.2 10.1 7.4 3.5 6.0 2.4 3.0 3.6 1.4 0.9 2.6 1.1 7.8 5.1 7.7 9.3 43.6 4.1 0.0 4.2 3.4 6.1 10.0 7.7 7.7 5.0 6.5 5.4 5.6 6.6 0.9 3.1 4.0 0.8 2.2 1.6 6.4 3.9 3.9 2.1 29.5 3.4 1.0 6.6 3.6 3.3 0.3 1.8 3.8 6.1 0.5 6.6 8.6 3.3 1.5 SLC25A42 MGC26694 ENSG00000181035 "Solute carrier family 25 member 42" Q86VD7 19 19063994-19113030 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.7;Hepatocytes: 52.1;Proximal tubular cells: 39.6;Rod photoreceptor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.7;MAIT T-cell: 1.4;memory B-cell: 3.3;memory CD4 T-cell: 1.5;memory CD8 T-cell: 2.4;naive B-cell: 3.2;naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.4;NK-cell: 1.8;T-reg: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.3;NK-cells: 1.8;T-cells: 2.7" "Cell line enhanced" "Detected in many" "K-562: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049449 Approved Supported Mitochondria Yes No "Cluster 43: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA049449: AB_2680772" "unprognostic (2.27e-1)" "prognostic favorable (5.04e-4)" "unprognostic (5.79e-2)" "unprognostic (5.67e-2)" "unprognostic (1.35e-1)" "unprognostic (3.42e-3)" "unprognostic (1.27e-3)" "prognostic favorable (4.11e-4)" "unprognostic (6.89e-2)" "unprognostic (2.73e-1)" "unprognostic (1.37e-3)" "unprognostic (3.04e-2)" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.39e-2)" "unprognostic (4.17e-2)" "unprognostic (2.03e-2)" 8.5 7.5 17.2 4.3 16.9 8.3 7.9 14.5 18.3 13.1 16.7 8.4 5.1 10.1 3.7 5.2 12.5 3.5 15.8 17.9 16.9 34.1 82.0 6.6 9.0 14.9 15.2 16.9 11.3 6.0 14.4 2.6 14.7 9.9 2.4 8.4 9.2 5.2 46.5 6.7 9.3 4.9 13.9 12.7 8.3 7.0 18.0 8.1 25.6 32.6 7.5 9.6 9.1 13.9 7.3 1.0 1.8 3.2 6.8 5.6 2.8 3.5 5.2 5.3 6.0 1.4 14.3 5.2 8.0 3.3 5.3 1.3 3.7 2.9 3.0 1.3 7.0 1.8 2.0 11.8 5.4 0.8 3.6 5.6 2.0 4.0 2.4 4.3 2.4 16.8 20.9 9.2 2.8 6.6 9.0 8.4 1.0 2.0 7.4 6.8 3.2 10.2 2.1 1.3 2.0 1.5 3.7 0.1 1.6 2.4 6.5 4.1 2.2 3.9 2.2 8.2 3.4 10.7 6.2 4.1 4.1 11.2 2.0 0.0 0.1 0.1 2.7 0.3 1.4 3.3 1.5 2.4 0.2 3.2 1.0 1.4 0.0 1.8 0.3 0.4 1.7 0.9 17.2 16.9 14.5 18.3 17.9 16.9 14.9 15.2 14.7 13.9 18.0 13.9 4.6 0.0 13.1 12.4 14.2 3.2 2.8 3.3 2.8 67.7 5.9 6.6 9.7 5.7 4.1 9.2 18.8 7.7 16.5 3.1 13.7 1.5 1.2 2.5 5.4 4.1 8.4 13.7 18.6 3.1 3.8 5.1 4.1 3.6 3.8 8.3 5.3 52.1 1.8 3.3 25.0 3.8 6.1 0.6 1.9 1.6 5.0 1.4 3.6 6.5 1.3 12.5 32.0 16.1 8.6 2.5 4.6 6.4 16.4 2.4 9.2 39.6 3.0 41.4 6.6 9.6 5.8 10.6 7.6 0.9 2.8 4.7 10.9 8.0 3.1 1.7 SLC26A9 ENSG00000174502 "Solute carrier family 26 member 9" Q7LBE3 1 205913048-205943460 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "salivary gland: 72.4;stomach 1: 33.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 50.1;Cardiomyocytes: 26.2;Gastric mucus-secreting cells: 29.0;Proximal tubular cells: 25.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;Hep G2: 5.1;OE19: 22.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA051485 Enhanced Approved "Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" "HPA051485: AB_2681503" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-1)" "unprognostic (1.83e-2)" "prognostic favorable (8.55e-5)" "unprognostic (1.26e-1)" "unprognostic (1.68e-1)" "unprognostic (3.49e-1)" "unprognostic (8.07e-2)" "unprognostic (8.85e-2)" "unprognostic (3.41e-1)" "unprognostic (2.43e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (7.45e-3)" "unprognostic (2.01e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 1.3 0.2 0.0 0.0 0.1 0.0 7.7 0.0 0.3 0.3 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 72.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 33.9 0.0 0.1 0.0 0.4 0.3 5.3 0.0 0.5 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.3 0.0 0.1 0.1 0.0 3.2 50.1 1.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.2 0.0 2.7 1.8 0.0 0.0 0.0 0.0 1.9 4.3 0.5 0.2 0.0 0.3 0.0 0.0 0.1 2.2 0.0 1.7 29.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.2 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.0 0.0 0.4 0.0 25.4 2.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 1.5 0.0 0.4 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocytes: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 27.7;SK-MEL-30: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 18.5 24.2 32.9 4.5 41.5 1.5 19.3 37.3 39.0 22.0 45.9 15.2 3.6 13.1 2.9 8.5 17.0 8.2 29.0 32.0 32.8 10.9 7.9 10.4 4.7 41.1 40.3 33.0 14.4 17.7 19.3 6.2 38.6 23.2 1.8 4.0 24.1 10.3 24.9 14.4 7.6 3.9 34.4 10.5 13.7 17.5 35.9 2.2 16.8 12.4 1.6 13.9 14.0 46.7 6.2 3.0 4.1 9.8 27.7 15.2 3.5 4.4 11.2 4.8 7.2 0.5 18.2 2.1 8.1 7.2 4.3 7.3 0.4 6.8 1.3 2.4 1.4 1.2 0.5 2.3 5.4 0.5 6.4 14.1 4.6 4.8 1.9 19.7 3.3 3.9 0.8 1.3 3.2 2.5 3.3 4.9 1.2 6.0 5.2 4.7 3.2 1.4 3.2 1.8 1.4 2.9 3.0 1.5 47.8 2.5 5.2 1.6 2.1 9.4 6.1 7.5 3.0 4.0 3.1 0.7 9.6 5.3 6.7 0.0 9.2 0.2 1.4 4.0 2.6 0.4 1.0 1.7 6.3 0.3 1.3 1.7 0.0 1.6 1.8 6.5 0.7 4.6 32.9 41.5 37.3 39.0 32.0 32.8 41.1 40.3 38.6 34.4 35.9 46.7 19.7 3.2 11.9 84.5 1.8 6.6 14.1 12.7 10.2 8.4 15.5 26.9 19.5 11.5 11.1 9.2 27.1 4.3 8.3 1.2 1.9 11.1 1.1 8.4 6.9 7.8 5.4 0.8 16.1 4.8 15.6 10.4 9.2 4.9 2.5 8.4 10.4 8.1 26.1 6.7 23.9 3.0 6.1 22.4 4.0 2.5 21.5 13.4 8.8 15.0 14.7 11.6 4.1 37.2 67.5 5.2 0.6 11.7 1.7 12.0 0.1 3.6 16.1 17.7 6.6 10.9 7.3 9.1 5.8 5.0 4.5 2.3 4.9 13.8 2.2 8.7 SLC27A6 "ACSVL2, FACVL2, FATP6, VLCS-H1" ENSG00000113396 "Solute carrier family 27 member 6" Q9Y2P4 5 128538013-129033642 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 24.4;fallopian tube: 21.3;heart muscle: 23.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 25.0;Cardiomyocytes: 29.6;Cytotrophoblasts: 54.8;Extravillous trophoblasts: 37.3;Muller glia cells: 33.0;Skeletal myocytes: 18.0;Syncytiotrophoblasts: 27.5" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 19.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BEWO: 43.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA008987 Approved Approved "Nuclear bodies" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies" "HPA008987: AB_1857065" "unprognostic (5.39e-5)" "unprognostic (4.79e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-1)" "unprognostic (3.55e-1)" "unprognostic (1.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.53e-1)" "unprognostic (2.64e-1)" "unprognostic (2.14e-1)" "unprognostic (2.54e-2)" "unprognostic (9.66e-4)" 0.4 24.4 1.8 0.3 2.4 0.1 3.0 3.0 1.4 3.9 0.7 0.9 0.4 4.3 0.2 4.2 21.3 2.7 23.5 1.2 3.6 0.0 0.1 0.8 0.2 9.7 5.2 9.7 0.1 0.0 6.0 6.7 7.5 3.6 1.7 7.4 3.5 0.3 0.4 2.0 1.1 0.8 5.8 0.1 0.5 13.0 5.5 9.6 1.8 0.9 5.7 1.1 2.9 8.4 0.0 0.0 0.1 0.0 0.0 0.0 43.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.9 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 3.5 0.0 3.3 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.3 0.3 4.4 0.0 5.1 0.0 3.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 3.0 1.4 1.2 3.6 9.7 5.2 7.5 5.8 5.5 8.4 0.0 0.0 0.0 0.0 0.0 3.2 0.9 0.0 25.0 0.6 0.2 5.5 29.6 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.0 13.2 3.8 1.0 0.3 0.0 0.0 0.4 0.0 37.3 2.7 0.0 1.9 0.0 1.7 0.0 0.0 3.8 3.3 4.6 0.0 0.0 0.0 0.4 2.8 0.3 0.2 0.0 0.0 0.0 33.0 0.0 1.0 1.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.9 0.0 18.0 0.3 1.1 1.0 1.8 0.9 27.5 0.0 2.3 0.1 0.1 SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 49.1;kidney: 48.2;liver: 111.3" "Group enriched" "Detected in some" 5 "Hepatocytes: 38.6;Hofbauer cells: 54.3;Proximal enterocytes: 86.9;Proximal tubular cells: 93.4" "Group enriched" "Detected in some" 63 "liver cancer: 10.9;renal cancer: 33.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: AB_2670187, HPA056247: " "unprognostic (3.81e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.49e-2)" "unprognostic (5.08e-2)" "unprognostic (7.08e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (1.35e-1)" "unprognostic (7.42e-2)" "unprognostic (7.72e-3)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.0 37.9 0.0 0.5 0.1 0.7 0.2 1.0 0.1 0.3 48.2 111.3 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 1.2 0.7 0.0 0.0 0.0 0.1 0.0 1.5 0.0 49.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.3 0.9 0.3 0.7 0.4 0.2 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.3 2.2 4.3 0.6 7.3 0.0 0.5 0.0 0.0 11.7 3.0 0.0 0.4 0.1 0.1 0.0 0.0 0.5 0.0 0.5 0.4 0.0 0.6 0.0 0.0 0.4 38.6 54.3 0.0 0.5 2.8 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.5 1.1 0.3 2.5 0.0 0.0 0.0 86.9 93.4 1.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 1.5 0.1 SLC29A1 ENT1 ENSG00000112759 "Solute carrier family 29 member 1 (Augustine blood group)" Q99808 6 44219553-44234142 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 216.6;Extravillous trophoblasts: 224.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 26 "eosinophil: 1046.6" "Lineage enriched" "Detected in all" 26 "granulocytes: 1046.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012384 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA012384: AB_1857073" "unprognostic (1.82e-2)" "unprognostic (1.41e-2)" "unprognostic (1.81e-1)" "unprognostic (2.49e-3)" "unprognostic (2.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (1.38e-2)" "unprognostic (4.60e-2)" "unprognostic (9.02e-2)" "unprognostic (1.34e-1)" 76.4 95.8 10.2 22.3 10.2 53.4 50.4 13.0 14.8 25.4 4.5 59.7 13.1 37.3 15.9 25.3 34.5 44.2 119.7 10.1 12.2 17.8 57.9 33.1 25.9 13.2 10.2 12.9 91.2 22.8 22.6 58.8 15.3 16.5 17.8 21.1 35.6 19.3 144.5 53.0 17.2 46.2 9.5 14.5 53.7 14.9 10.7 81.3 30.7 100.7 17.0 32.8 17.7 10.8 85.3 84.2 58.5 95.1 87.8 8.1 347.1 61.2 24.0 83.6 57.4 91.8 34.8 171.2 60.8 18.5 51.7 103.8 105.2 72.8 51.9 97.6 97.2 150.5 57.8 122.5 14.1 170.3 139.7 10.9 18.4 123.0 42.7 171.6 216.0 137.2 205.4 100.1 46.9 94.0 142.0 114.4 89.0 218.4 55.4 94.0 117.8 208.9 49.1 49.5 75.0 97.0 18.4 58.9 43.9 61.5 80.7 107.1 333.1 46.4 74.8 62.6 117.7 67.0 93.8 221.9 28.8 136.8 57.1 21.9 12.1 1046.6 5.1 38.8 4.2 4.4 2.7 3.9 6.8 2.4 1.1 2.4 1.8 3.1 32.5 40.0 8.2 6.6 10.2 10.2 13.0 14.8 10.1 12.2 13.2 10.2 15.3 9.5 10.7 10.8 64.2 0.0 10.5 1.3 4.0 10.7 9.0 4.1 2.2 10.9 20.2 30.1 46.4 17.2 6.0 7.3 14.6 216.6 5.7 3.0 3.9 24.2 0.5 4.3 3.5 31.7 31.2 49.2 18.4 56.7 224.6 40.0 26.5 11.2 8.2 25.4 25.7 16.7 63.6 5.0 25.4 2.9 79.3 37.0 13.3 2.8 32.9 19.2 35.6 16.9 8.3 4.3 0.0 5.0 2.6 61.9 3.4 53.8 14.2 18.2 0.7 0.9 6.9 11.9 92.1 21.0 22.5 0.4 11.0 4.6 15.6 42.0 3.2 4.1 6.2 9.8 SLC2A11 "GLUT10, GLUT11" ENSG00000133460 "Solute carrier family 2 member 11" Q9BYW1 22 23856703-23886309 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 298.2;Rod photoreceptor cells: 188.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-BR-3: 9.2" "Low region specificity" "Detected in all" "HPA042960, HPA071184" Uncertain Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Cell Junctions" Nucleoplasm "HPA042960: AB_2678241, HPA071184: AB_2686355" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (3.69e-2)" "unprognostic (6.97e-2)" "unprognostic (7.93e-2)" "unprognostic (1.32e-1)" "unprognostic (4.24e-2)" "unprognostic (1.60e-3)" "unprognostic (3.53e-1)" "unprognostic (4.89e-2)" "prognostic favorable (3.83e-4)" "unprognostic (2.32e-1)" "prognostic favorable (5.77e-7)" "unprognostic (1.25e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (6.29e-2)" 2.3 6.3 3.9 1.7 3.7 1.1 3.3 5.3 4.5 4.8 3.4 5.2 1.2 3.4 3.0 1.6 3.6 1.3 10.2 3.3 4.1 16.5 5.1 2.3 2.7 3.7 3.7 4.9 12.9 6.1 13.2 2.7 4.1 5.1 2.0 19.5 3.9 2.9 6.3 2.3 4.6 1.8 3.0 4.2 4.4 3.2 4.1 0.7 7.2 1.9 2.2 4.3 2.2 3.5 2.2 1.0 1.2 5.7 1.2 2.5 0.6 1.3 1.6 1.4 0.9 1.3 1.5 2.7 0.7 1.7 1.2 1.7 2.4 0.8 0.7 2.0 2.2 1.3 2.5 2.0 1.8 1.3 1.4 1.0 2.4 2.0 1.7 6.3 0.5 2.1 0.5 6.4 0.7 2.2 0.3 0.5 2.1 1.3 1.6 3.7 0.2 3.1 4.3 0.6 3.2 1.8 0.6 9.2 2.2 1.5 4.8 0.7 0.4 0.5 0.9 0.5 0.6 5.5 1.6 2.6 1.1 0.9 1.4 0.4 0.1 0.4 0.2 0.3 0.1 0.6 0.2 0.2 0.0 0.5 0.4 0.2 0.2 0.3 0.2 1.4 0.0 0.1 3.9 3.7 5.3 4.5 3.3 4.1 3.7 3.7 4.1 3.0 4.1 3.5 2.9 19.2 15.0 14.4 23.4 3.2 9.3 4.4 8.6 56.0 15.0 13.5 31.2 7.2 5.6 25.8 298.2 9.8 15.5 5.7 13.7 4.9 8.4 4.8 8.2 4.4 10.8 5.0 21.6 5.6 9.8 8.3 5.1 5.3 2.5 19.5 6.1 7.3 5.8 37.0 30.0 5.8 10.2 4.8 4.6 10.4 9.3 4.3 3.6 4.7 4.2 16.4 10.3 8.0 14.2 2.7 2.7 9.8 15.2 7.3 3.7 24.7 6.3 188.8 0.0 11.8 7.5 4.2 5.7 5.3 3.1 20.0 8.3 28.3 7.5 6.0 SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Oligodendrocytes: 14.5;Syncytiotrophoblasts: 36.7" "Cancer enriched" "Detected in many" 6 "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;hTERT-RPE1: 14.8;SuSa: 21.7;U-2 OS: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Cell Junctions" "HPA031593: AB_10600810, HPA031594: AB_2673948" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-2)" "unprognostic (5.55e-3)" "unprognostic (2.18e-1)" "unprognostic (6.02e-2)" "unprognostic (2.24e-3)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.55e-3)" 0.5 1.0 3.6 0.3 4.8 0.0 1.1 7.8 4.6 3.0 87.3 2.1 7.3 8.2 2.1 6.1 2.8 2.6 10.7 5.7 2.6 5.8 6.8 3.1 0.1 2.3 3.1 1.2 1.1 2.3 1.4 1.6 2.5 22.4 1.0 2.3 5.1 9.3 3.8 2.7 9.8 3.1 1.6 0.1 14.3 0.4 3.4 1.0 0.2 4.1 1.2 3.5 1.2 3.1 2.5 0.9 2.3 0.0 1.4 0.7 0.1 1.5 5.4 0.7 2.9 0.0 7.6 0.3 1.2 0.1 5.7 5.9 0.0 0.5 1.0 0.0 5.3 0.0 0.8 0.1 0.2 0.0 0.0 1.0 0.5 0.6 0.1 14.8 0.4 0.4 0.5 0.8 0.1 0.8 0.1 0.1 2.0 0.0 0.5 0.0 1.0 2.2 1.6 0.8 0.2 0.7 0.1 2.1 0.0 21.7 0.1 0.0 0.1 0.2 7.6 0.2 0.9 3.2 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 4.8 7.8 4.6 5.7 2.6 2.3 3.1 2.5 1.6 3.4 3.1 0.2 0.0 7.7 24.8 0.1 2.0 1.0 3.3 8.6 0.4 0.5 2.2 6.3 0.0 2.2 0.0 0.0 2.0 0.1 1.2 3.9 1.5 0.1 3.4 0.4 2.3 4.2 0.0 8.0 0.2 0.6 2.2 2.6 1.6 0.0 0.4 0.0 1.1 0.3 0.0 3.2 0.2 6.1 0.0 0.3 0.0 0.0 0.1 0.0 4.7 0.1 9.8 0.0 4.5 14.5 1.1 2.4 1.5 1.6 10.5 0.5 0.5 10.4 0.5 0.0 2.1 1.3 0.0 0.0 8.6 1.8 36.7 0.2 3.5 0.4 1.3 SLC38A7 FLJ10815 ENSG00000103042 "Solute carrier family 38 member 7" Q9NVC3 16 58665109-58684770 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 32.8" "Group enriched" "Detected in all" 13 "Early spermatids: 271.8;Late spermatids: 753.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041777, HPA049428" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA041777: AB_10796782, HPA049428: " "unprognostic (2.16e-3)" "unprognostic (2.30e-2)" "unprognostic (6.23e-3)" "prognostic favorable (6.87e-4)" "unprognostic (3.49e-1)" "unprognostic (8.08e-3)" "unprognostic (9.76e-3)" "unprognostic (6.34e-3)" "unprognostic (1.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.77e-1)" "unprognostic (4.90e-2)" "prognostic favorable (2.87e-4)" "unprognostic (1.85e-1)" "unprognostic (4.38e-2)" "unprognostic (7.50e-2)" "unprognostic (4.93e-3)" 6.0 11.4 7.5 6.0 7.8 2.6 5.3 6.0 8.9 5.1 6.1 5.1 4.3 5.5 6.2 6.5 4.0 5.6 15.9 7.9 7.4 7.3 13.6 5.4 4.3 7.7 7.6 4.6 4.8 14.1 7.2 7.5 8.1 5.5 5.9 4.7 6.2 4.6 9.4 5.3 5.5 7.4 5.8 10.3 5.4 32.8 9.8 3.6 7.8 8.3 4.6 5.4 4.9 7.0 6.9 10.9 10.8 16.5 22.0 12.9 19.3 16.2 18.7 22.7 15.6 9.9 11.0 4.5 8.9 22.9 17.9 15.9 10.2 11.7 13.3 2.8 9.4 5.1 9.3 16.5 32.9 10.6 14.0 25.9 23.6 16.1 10.3 12.3 23.5 10.4 14.9 6.3 16.7 8.0 4.3 6.3 11.7 7.5 16.0 15.2 11.6 12.1 10.0 15.4 7.9 11.3 25.7 17.0 7.0 14.4 7.6 4.2 18.7 12.3 9.3 21.8 5.0 9.7 6.7 5.2 16.8 6.3 9.3 0.1 6.8 2.0 4.0 6.6 2.2 1.3 2.4 2.9 4.5 2.5 1.9 2.1 0.5 1.8 6.4 1.7 1.8 5.5 7.5 7.8 6.0 8.9 7.9 7.4 7.7 7.6 8.1 5.8 9.8 7.0 3.3 3.2 4.4 7.8 2.0 3.8 4.0 4.4 1.2 9.8 4.7 3.2 12.8 4.3 4.8 11.0 12.5 8.4 5.0 3.7 3.9 14.0 271.8 3.5 6.8 6.2 13.1 2.1 13.3 8.5 9.5 5.1 9.7 6.0 1.3 10.7 8.2 9.3 38.6 16.8 15.5 3.1 12.2 10.1 8.2 753.3 9.6 11.6 8.8 9.4 4.0 7.1 8.2 5.0 7.6 12.8 2.7 8.6 1.8 3.7 4.8 5.9 3.8 7.1 6.6 4.8 5.1 6.9 7.6 4.6 4.3 15.3 2.7 8.6 4.9 3.2 SLC41A1 MgtE ENSG00000133065 "Solute carrier family 41 member 1" Q8IVJ1 1 205789094-205813748 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 99.3;tongue: 75.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 175.0;Theca cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014721, HPA015138" Uncertain Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA014721: , HPA015138: AB_1857160" "unprognostic (1.18e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.77e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (2.37e-3)" "unprognostic (5.23e-2)" "unprognostic (5.53e-3)" "unprognostic (1.11e-1)" "unprognostic (1.87e-2)" "unprognostic (4.46e-2)" "unprognostic (3.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (1.65e-1)" 9.7 10.8 10.1 6.4 10.4 5.8 4.7 11.0 8.2 4.8 36.7 5.8 2.1 6.5 5.1 5.6 11.0 7.1 99.3 8.6 6.4 9.2 1.4 8.4 7.4 11.1 10.2 11.3 61.6 9.3 4.6 3.7 9.5 7.5 1.8 6.1 3.7 6.7 48.8 3.8 3.8 6.0 8.9 5.3 9.8 18.5 13.7 5.7 17.8 75.9 5.1 6.2 3.9 9.5 18.2 16.1 9.6 15.6 11.7 11.6 13.2 17.9 17.8 18.2 15.9 8.0 10.1 25.9 11.3 16.5 14.9 18.5 9.5 13.4 6.2 48.6 14.8 6.4 16.5 1.2 11.2 0.0 17.4 14.9 10.8 20.8 14.7 14.9 11.3 20.5 11.9 10.5 14.7 11.2 11.8 1.8 11.5 4.8 7.1 13.8 29.0 6.4 4.1 22.0 8.1 10.4 14.0 12.3 11.0 8.0 8.8 6.7 14.3 21.5 13.8 19.9 19.2 34.7 24.9 8.5 16.6 8.3 13.6 0.0 0.1 0.0 1.6 0.1 2.0 0.6 1.5 1.5 0.0 0.7 1.4 1.5 0.0 0.4 0.0 0.0 1.5 1.0 10.1 10.4 11.0 8.2 8.6 6.4 11.1 10.2 9.5 8.9 13.7 9.5 18.2 3.2 23.0 20.5 11.2 20.8 24.3 4.6 10.8 14.6 14.4 10.2 175.0 5.7 8.5 0.0 50.1 1.8 11.5 1.6 1.9 9.6 2.4 6.8 9.8 24.1 6.0 6.5 5.3 11.0 14.5 15.7 11.7 6.2 7.0 13.9 8.6 2.2 3.4 18.5 6.6 2.7 4.1 2.4 6.5 2.7 9.9 3.5 8.8 15.9 0.8 17.0 8.2 7.1 8.3 9.3 1.3 9.4 8.3 24.9 0.0 15.7 7.9 20.3 0.0 29.7 16.1 8.1 12.9 7.5 18.2 3.1 14.5 100.2 1.5 22.0 SLC47A1 "FLJ10847, MATE1" ENSG00000142494 "Solute carrier family 47 member 1" Q96FL8 17 19495385-19579034 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 127.3;kidney: 100.3;liver: 103.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 189.2;Hepatocytes: 43.3;Proximal tubular cells: 52.9;Skeletal myocytes: 67.8" "Cancer enhanced" "Detected in many" "renal cancer: 37.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 12.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 6.6;granulocytes: 12.2" "Cell line enhanced" "Detected in many" "A549: 21.3;AN3-CA: 16.7;Hep G2: 41.5;U-266/70: 31.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021987 Enhanced NA NA 18000 "Cluster 49: Eosinophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "HPA021987: AB_1857185" "unprognostic (1.17e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.54e-8)" "unprognostic (7.87e-2)" "unprognostic (8.34e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.88e-5)" "unprognostic (4.84e-2)" "unprognostic (6.89e-2)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.06e-5)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.91e-2)" "unprognostic (9.40e-2)" 1.9 127.3 2.1 0.8 2.6 2.7 1.3 3.5 15.8 29.4 9.3 2.0 1.3 16.2 2.5 1.9 7.4 3.8 5.4 15.7 1.6 100.3 103.9 7.0 1.6 3.0 2.5 7.7 0.3 1.4 16.5 0.4 3.1 6.3 1.0 1.2 2.6 12.3 34.1 25.0 1.3 7.7 2.5 3.7 1.2 14.5 4.3 1.5 6.2 37.7 1.3 1.0 10.6 3.3 0.1 21.3 0.6 16.7 0.5 0.1 0.1 0.6 0.5 2.5 2.3 0.0 0.6 0.2 3.9 3.1 8.3 0.1 7.4 0.6 0.6 0.1 9.8 0.2 10.6 41.5 0.2 0.2 0.5 0.4 3.7 1.9 0.3 2.8 5.9 0.0 0.0 0.0 0.0 3.0 0.1 0.4 2.2 0.3 0.8 0.2 0.2 0.2 0.0 1.3 3.9 3.4 7.0 0.1 1.9 5.6 7.1 1.9 0.0 0.1 0.8 0.3 2.0 31.0 13.1 0.1 0.8 0.1 3.6 0.3 1.4 12.2 0.3 0.9 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.6 0.2 0.0 0.1 6.6 0.0 0.5 2.1 2.6 3.5 15.8 15.7 1.6 3.0 2.5 3.1 2.5 4.3 3.3 0.5 6.4 3.7 0.7 1.3 4.7 2.3 0.4 6.2 0.9 0.1 0.8 4.1 4.3 0.1 1.8 0.0 0.0 1.7 0.0 3.9 0.1 15.5 3.0 1.3 1.2 0.0 0.0 3.5 0.0 0.0 4.4 0.0 9.2 5.7 189.2 0.0 43.3 1.5 0.0 14.4 0.0 0.0 2.9 1.2 4.8 3.7 2.5 1.8 3.7 0.4 1.4 0.0 2.5 0.3 0.0 0.0 1.5 3.9 2.3 0.0 52.9 0.8 0.9 6.6 67.8 3.3 0.6 1.1 1.1 6.7 0.0 1.7 0.3 0.0 1.5 SLC4A3 "AE3, SLC2C" ENSG00000114923 "Solute carrier family 4 member 3" P48751 2 219627394-219641980 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 283.1;ovary: 124.1" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 207.1;Horizontal cells: 558.6" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "myeloid DC: 1.4;plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 54 "dendritic cells: 5.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063498 Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA063498: AB_2685025" "unprognostic (9.49e-2)" "unprognostic (5.72e-3)" "unprognostic (8.92e-4)" "unprognostic (1.77e-2)" "unprognostic (6.61e-3)" "unprognostic (1.47e-1)" "unprognostic (2.60e-1)" "unprognostic (2.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-1)" "unprognostic (8.15e-3)" "unprognostic (1.97e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.12e-4)" 6.3 16.7 36.1 1.0 36.6 0.4 3.9 21.2 32.1 11.4 6.3 2.9 0.7 15.3 2.7 3.2 9.3 2.3 283.1 31.7 34.5 9.3 0.3 1.6 0.9 44.1 20.7 124.1 3.9 7.7 41.4 2.7 43.1 10.4 0.2 13.0 3.8 5.3 0.9 2.0 1.1 3.7 10.6 3.3 2.7 14.2 32.7 1.0 2.5 0.6 0.6 2.6 4.7 18.0 6.9 0.2 2.3 6.8 0.4 0.4 4.9 4.1 4.2 5.4 3.8 4.8 3.8 0.0 1.6 1.5 9.3 3.8 1.2 7.3 1.6 0.0 1.0 0.0 0.1 0.1 1.1 0.1 0.3 3.1 7.0 0.0 2.1 13.4 0.0 0.0 0.3 0.0 1.6 2.3 0.0 0.0 3.8 0.2 5.5 0.0 0.0 0.0 3.7 1.5 1.3 6.7 2.7 6.9 3.7 7.2 0.7 1.7 0.0 3.4 6.0 0.0 3.3 0.0 0.0 0.0 2.7 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 36.1 36.6 21.2 32.1 31.7 34.5 44.1 20.7 43.1 10.6 32.7 18.0 0.3 0.0 0.0 19.2 0.2 0.3 0.7 1.5 0.0 14.4 2.2 4.8 207.1 0.0 0.8 1.8 0.0 11.4 13.5 0.0 1.9 3.0 2.3 0.9 3.5 1.8 0.0 0.0 11.5 1.7 3.0 10.4 0.0 1.4 0.0 38.3 0.0 0.0 1.8 558.6 32.7 0.0 0.0 0.3 5.6 25.6 15.2 1.1 0.0 3.7 1.3 7.6 0.0 3.5 0.6 1.1 0.0 22.6 0.0 0.4 0.0 0.3 0.2 7.5 6.6 3.9 3.5 0.6 1.2 0.0 0.9 13.8 0.1 8.7 0.0 0.1 SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 6 "Proximal enterocytes: 768.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "OE19: 34.2" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" "Nuclear membrane, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.1 4.2 0.1 0.0 9.7 0.2 0.1 12.3 0.0 10.7 528.1 0.5 3.5 5.1 1.1 26.9 75.2 0.1 0.0 6.6 1.7 2.1 0.3 0.1 0.0 0.0 1.6 0.3 1.0 0.0 0.1 3.0 9.7 0.2 19.0 2.4 0.3 13.5 302.4 0.7 0.0 2.9 7.2 2.3 0.5 0.1 0.0 0.0 4.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 34.2 0.0 0.0 0.0 2.1 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.2 0.6 1.7 4.2 0.0 0.0 11.6 6.5 115.2 115.8 8.2 0.0 0.0 0.0 0.2 19.8 0.0 3.0 38.4 2.4 1.4 1.0 25.4 0.0 0.4 1.4 0.0 1.4 5.6 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 34.1 0.0 0.0 0.0 71.3 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 32.6 1.5 0.0 17.6 768.7 6.4 2.0 0.0 0.0 0.0 0.7 10.1 4.2 2.0 5.5 0.0 0.1 0.1 41.2 6.7 SMDT1 "C22orf32, DDDD, dJ186O1.1, EMRE" ENSG00000183172 "Single-pass membrane protein with aspartate rich tail 1" Q9H4I9 22 42079691-42084284 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032117, HPA060340" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA032117: AB_10601093, HPA060340: AB_2684257" "unprognostic (1.11e-2)" "unprognostic (1.46e-3)" "unprognostic (5.77e-2)" "prognostic favorable (5.32e-8)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (2.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.84e-2)" "prognostic favorable (5.87e-4)" "unprognostic (2.96e-1)" "prognostic favorable (2.36e-9)" "unprognostic (1.91e-1)" "unprognostic (2.65e-1)" "unprognostic (1.45e-1)" "unprognostic (9.72e-3)" 12.2 13.9 21.6 6.1 22.2 17.6 19.5 25.7 27.7 14.6 21.2 14.7 10.3 12.3 19.5 12.6 15.2 7.4 20.0 22.1 22.0 18.2 15.1 9.7 16.1 21.6 21.4 22.5 21.5 18.0 14.9 7.3 22.2 16.1 11.2 16.0 22.7 13.4 35.6 14.8 13.5 8.4 21.3 12.6 17.7 6.9 21.3 12.4 18.6 37.9 12.2 12.4 11.9 22.4 5.7 3.7 7.4 8.9 13.1 9.5 5.8 2.0 10.0 12.1 10.5 7.1 5.3 7.8 2.4 10.3 3.4 6.1 9.8 10.4 7.7 3.8 15.7 4.7 8.1 10.3 16.5 8.6 5.9 7.4 17.3 4.8 9.9 6.9 12.2 5.1 7.9 12.3 8.4 11.2 12.1 13.0 2.8 14.1 2.7 10.8 6.5 20.8 15.5 6.4 9.2 6.0 5.0 11.1 12.8 3.7 9.3 9.3 4.8 5.1 5.3 4.5 3.9 8.2 9.8 16.9 7.9 8.5 4.1 4.0 5.8 2.9 3.1 3.1 5.9 5.9 8.6 4.5 8.4 7.2 9.3 6.0 0.5 5.5 4.5 6.4 5.4 5.4 21.6 22.2 25.7 27.7 22.1 22.0 21.6 21.4 22.2 21.3 21.3 22.4 161.1 83.3 109.3 11.8 295.0 166.7 202.2 157.3 191.2 71.6 400.9 477.3 350.9 237.4 160.3 204.1 20.9 308.7 127.8 285.6 573.2 160.0 114.0 156.8 81.1 138.2 345.2 135.7 10.5 199.6 190.6 127.8 150.3 127.2 91.4 55.4 161.3 380.1 256.1 55.5 12.8 356.5 262.4 164.5 200.6 131.9 189.2 187.7 211.7 5.6 125.8 196.4 124.6 7.5 13.8 193.7 314.0 149.0 275.8 238.2 486.7 623.4 223.7 109.5 124.9 133.6 202.7 256.0 55.5 271.5 274.1 308.8 186.3 151.7 308.8 272.2 SMIM1 Vel ENSG00000235169 "Small integral membrane protein 1 (Vel blood group)" B2RUZ4 1 3772749-3775982 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.3;testis: 42.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 84.1;Erythroid cells: 404.4;Granulosa cells: 81.5;Proximal tubular cells: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "eosinophil: 48.5" "Lineage enriched" "Detected in many" 12 "granulocytes: 48.5" "Group enriched" "Detected in many" 4 "HEL: 68.0;Hep G2: 32.5;K-562: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA069088 Enhanced NA NA 340000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA069088: AB_2686080" "unprognostic (9.50e-3)" "unprognostic (7.19e-4)" "unprognostic (5.40e-2)" "unprognostic (2.10e-2)" "unprognostic (2.50e-3)" "unprognostic (3.25e-1)" "unprognostic (2.63e-3)" "unprognostic (2.13e-2)" "unprognostic (2.31e-2)" "unprognostic (9.85e-2)" "unprognostic (2.90e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-2)" "unprognostic (7.10e-2)" "unprognostic (2.91e-2)" "unprognostic (5.56e-2)" "unprognostic (1.32e-2)" 2.6 2.7 1.8 0.4 2.6 32.1 3.2 3.8 3.0 5.8 6.2 2.9 0.7 2.8 1.1 1.4 3.4 1.3 40.3 1.4 3.9 16.9 13.1 3.7 1.0 8.7 5.3 8.7 9.4 4.3 16.0 2.1 9.0 6.9 0.1 0.4 17.3 5.5 1.1 2.1 2.1 0.2 5.5 4.0 6.6 42.2 3.6 0.4 9.3 0.2 0.5 3.4 3.6 6.2 0.3 1.4 1.4 3.0 0.0 0.0 5.0 0.9 1.2 0.0 0.0 3.5 3.9 0.1 6.3 0.0 0.2 1.3 0.4 1.5 0.0 6.1 3.6 68.0 0.0 32.5 2.4 0.0 1.2 2.1 0.8 0.3 0.5 2.9 0.0 0.3 33.9 1.2 0.0 7.8 0.0 2.1 0.3 3.4 6.0 0.0 0.0 9.9 3.8 1.0 1.6 6.3 0.2 6.8 4.8 0.5 7.0 3.7 0.4 0.0 0.8 0.0 0.0 2.8 0.8 0.2 0.0 0.0 0.2 4.4 2.0 48.5 1.1 1.0 0.4 2.5 1.6 0.6 0.6 3.7 4.0 1.9 3.2 0.2 0.4 0.6 1.2 2.2 1.8 2.6 3.8 3.0 1.4 3.9 8.7 5.3 9.0 5.5 3.6 6.2 1.1 6.4 20.1 0.7 5.9 1.7 13.1 4.4 10.2 0.4 31.1 35.9 57.0 8.6 8.1 16.5 0.0 23.4 1.4 1.6 84.1 17.2 10.8 3.7 1.2 3.9 5.4 404.4 0.1 14.5 18.8 10.1 6.6 3.5 1.3 81.5 3.9 50.2 10.4 1.7 0.1 3.9 8.2 8.9 1.0 27.8 9.9 8.5 42.7 0.0 4.3 47.0 2.1 0.0 1.6 13.7 1.7 9.8 11.1 10.2 1.9 247.9 2.2 1.5 0.0 3.6 4.3 8.7 20.4 1.7 1.1 6.7 4.6 3.0 4.3 9.1 SMIM10L2B "LINC00087, NCRNA00087, RP11-85L21.2" ENSG00000196972 "Small integral membrane protein 10 like 2B" P0DMW5 X 135094985-135098712 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 29.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.1;Cardiomyocytes: 4.8;Horizontal cells: 11.8;Muller glia cells: 5.0;Peritubular cells: 3.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;GAMG: 2.1;HHSteC: 1.8;HSkMC: 2.9;NTERA-2: 1.6" NA NA "Cluster 65: Brain - Ion transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (2.60e-2)" "unprognostic (3.08e-1)" "unprognostic (3.16e-2)" "unprognostic (1.18e-3)" "unprognostic (7.25e-3)" "unprognostic (9.55e-2)" "unprognostic (5.90e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (7.05e-2)" "unprognostic (4.69e-2)" "unprognostic (1.13e-2)" "prognostic favorable (2.41e-5)" "unprognostic (2.03e-3)" "unprognostic (1.94e-1)" "unprognostic (2.32e-2)" "unprognostic (4.98e-2)" 1.2 3.3 17.7 0.4 19.3 0.0 1.3 6.2 24.2 3.1 0.5 1.4 0.4 2.7 2.1 2.0 3.1 0.8 11.1 19.2 23.4 3.7 1.3 1.4 0.4 20.3 20.9 4.5 1.0 5.8 3.7 0.4 29.5 3.5 0.4 2.2 3.0 2.1 0.8 1.6 0.8 1.4 7.7 1.0 1.6 5.6 16.9 0.1 2.2 0.8 0.3 1.2 2.2 14.4 0.0 0.0 1.3 1.2 1.8 0.2 0.6 0.4 0.2 0.2 0.3 0.5 0.0 0.0 0.2 0.2 2.1 0.1 0.4 0.4 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.2 0.0 0.1 0.3 0.1 0.6 0.0 0.0 0.1 0.0 0.4 0.0 1.6 0.3 0.1 0.0 0.3 0.0 0.7 0.2 0.6 0.2 0.2 0.1 0.0 1.3 0.0 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 19.3 6.2 24.2 19.2 23.4 20.3 20.9 29.5 7.7 16.9 14.4 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.1 1.0 1.8 4.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.9 0.3 0.1 0.1 1.2 0.7 1.2 0.0 0.0 0.7 0.1 1.1 0.0 0.2 0.0 1.3 0.7 1.7 0.0 11.8 0.0 0.3 0.0 0.3 0.0 0.8 3.1 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.5 0.0 3.8 0.0 0.4 0.1 1.7 0.0 1.5 0.0 0.6 2.3 1.0 0.5 0.8 0.0 0.3 0.0 0.9 0.1 0.4 SMIM30 LINC00998 ENSG00000214194 "Small integral membrane protein 30" A4D0T7 7 113116718-113118560 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 126.9;Distal tubular cells: 414.8;Hofbauer cells: 243.9;Proximal tubular cells: 396.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.25e-1)" "unprognostic (1.73e-3)" "unprognostic (6.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.44e-3)" "unprognostic (3.89e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (7.25e-2)" "unprognostic (5.00e-3)" "unprognostic (7.07e-3)" "unprognostic (6.80e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.46e-2)" "unprognostic (1.82e-1)" "unprognostic (2.63e-1)" "unprognostic (1.35e-1)" 44.6 53.2 40.8 26.8 41.5 12.2 47.2 41.4 57.8 37.2 40.8 33.3 32.3 30.6 70.9 39.5 30.5 37.4 205.3 40.7 42.7 83.7 57.6 40.0 38.5 42.8 40.0 26.9 41.6 83.9 26.3 29.4 42.5 37.6 35.6 43.5 47.8 30.0 142.5 20.8 27.6 39.0 42.5 41.4 39.4 19.7 41.0 30.2 60.0 149.6 31.8 50.6 21.5 44.8 48.0 24.1 56.3 49.6 100.8 159.8 0.2 57.3 95.0 60.5 94.0 25.1 82.7 57.4 69.5 72.0 104.5 29.9 55.8 126.5 146.8 37.9 113.3 130.3 32.7 42.9 66.8 179.2 0.4 120.8 120.1 91.6 46.8 111.0 95.7 60.6 176.1 52.4 199.6 24.7 76.3 196.4 58.6 72.6 66.0 47.7 136.2 156.9 118.8 63.9 85.1 61.8 43.1 85.6 140.2 97.5 57.5 117.4 55.1 96.8 49.6 110.9 86.2 77.6 102.6 205.3 126.9 161.0 138.0 2.0 15.8 12.5 16.1 17.6 17.9 19.6 18.3 16.9 25.2 17.0 17.2 17.5 0.6 19.7 14.1 36.5 23.2 16.7 40.8 41.5 41.4 57.8 40.7 42.7 42.8 40.0 42.5 42.5 41.0 44.8 32.6 51.3 68.9 0.0 10.4 0.0 0.0 0.0 0.0 0.0 77.4 42.7 0.0 0.0 32.8 126.9 0.0 76.2 8.2 0.0 414.8 102.3 0.0 51.5 37.8 27.7 0.0 0.0 0.0 69.8 61.8 20.7 0.0 43.5 32.8 27.0 0.0 0.0 243.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 44.5 0.0 0.0 0.0 0.0 83.7 0.0 0.0 1.3 0.0 0.0 396.3 32.8 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 41.6 11.0 70.8 0.0 0.0 SMIM4 C3orf78 ENSG00000168273 "Small integral membrane protein 4" Q8WVI0 3 52534013-52579237 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 121.9;skeletal muscle: 130.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 252.4;Distal tubular cells: 213.2;Proximal tubular cells: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047771 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA047771: AB_2680150" "unprognostic (3.76e-3)" "unprognostic (3.19e-2)" "unprognostic (4.54e-2)" "unprognostic (4.89e-1)" "unprognostic (2.40e-1)" "unprognostic (1.48e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.78e-5)" "unprognostic (3.25e-2)" "unprognostic (4.25e-2)" "prognostic favorable (5.00e-4)" "unprognostic (6.35e-2)" "prognostic favorable (1.63e-4)" "unprognostic (8.72e-3)" "unprognostic (2.28e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-2)" 22.6 121.9 14.6 12.9 15.3 7.4 22.1 21.8 20.5 16.0 20.5 19.1 12.3 14.3 10.4 16.3 14.5 3.7 100.3 15.3 15.5 37.3 20.2 20.3 10.5 15.6 18.2 41.5 25.7 31.6 56.4 6.1 16.9 26.2 10.4 13.9 28.9 13.6 130.3 20.1 15.0 5.0 15.0 15.8 20.4 17.3 15.4 6.6 48.6 50.2 8.7 20.2 13.3 18.0 58.7 19.0 22.9 58.5 26.5 13.7 47.0 25.9 12.0 29.2 25.3 24.6 15.4 25.1 11.6 10.9 29.4 30.2 7.6 20.9 11.8 16.9 60.1 23.6 58.2 50.2 40.1 28.4 31.6 29.6 12.7 24.6 17.7 15.8 26.8 27.0 31.9 36.4 19.9 25.4 26.4 39.4 39.1 31.9 42.4 18.1 22.2 50.1 17.0 25.2 24.9 31.4 50.6 16.5 52.6 12.9 17.0 23.6 24.0 16.0 53.1 76.4 53.5 42.3 50.6 57.3 87.9 52.2 22.5 8.1 44.1 17.3 19.1 35.8 18.8 24.6 27.3 23.9 49.7 22.7 29.1 27.0 1.6 22.5 15.2 26.5 29.6 20.0 14.6 15.3 21.8 20.5 15.3 15.5 15.6 18.2 16.9 15.0 15.4 18.0 35.4 48.1 46.3 1.3 30.3 27.1 37.3 52.2 41.5 17.6 80.9 84.1 252.4 60.1 63.1 53.3 12.5 42.9 26.6 58.3 213.2 52.9 21.9 71.9 30.6 32.8 79.3 22.1 1.9 86.1 24.7 36.0 34.1 48.9 59.5 16.9 55.6 160.4 116.4 3.3 2.1 62.9 30.5 80.8 46.7 15.1 65.0 51.1 37.4 0.0 28.5 102.8 15.5 2.5 3.2 57.8 39.9 101.2 19.7 19.7 89.5 215.6 52.1 15.3 46.0 22.8 56.8 9.8 14.2 34.8 34.5 27.6 25.8 44.3 73.5 23.6 SMIM5 C17orf109 ENSG00000204323 "Small integral membrane protein 5" Q71RC9 17 75633434-75641404 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4" "Cell type enhanced" "Detected in many" "Collecting duct cells: 125.0;Distal tubular cells: 92.0;Endometrial ciliated cells: 69.4;Erythroid cells: 142.5;Glandular and luminal cells: 67.6;Urothelial cells: 90.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 56 "plasmacytoid DC: 207.6" "Lineage enriched" "Detected in many" 56 "dendritic cells: 207.6" "Cell line enhanced" "Detected in some" "HEL: 2.3;MCF7: 10.5;OE19: 2.8;SK-BR-3: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA065332, HPA071268" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Golgi apparatus" "HPA065332: AB_2685471, HPA071268: AB_2686377" "unprognostic (6.97e-2)" "prognostic favorable (5.52e-4)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (9.31e-2)" "unprognostic (1.05e-4)" "unprognostic (3.29e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-1)" "unprognostic (2.66e-2)" "unprognostic (3.52e-3)" "unprognostic (1.10e-1)" "prognostic favorable (1.12e-4)" "unprognostic (2.64e-1)" "unprognostic (4.94e-2)" "unprognostic (8.26e-2)" "unprognostic (2.58e-1)" 1.3 0.6 4.5 1.9 8.5 11.4 1.5 8.5 6.4 8.4 10.7 10.5 9.6 1.2 0.8 27.4 7.4 4.4 12.2 5.0 5.6 28.4 1.4 3.1 1.1 11.2 8.8 2.7 2.5 3.4 2.4 1.9 9.6 4.2 2.6 0.7 7.8 1.9 0.5 14.3 15.2 0.5 7.2 4.8 10.1 2.2 7.8 0.6 15.9 0.3 3.6 6.1 14.6 16.4 1.8 1.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.3 0.4 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 10.5 0.1 0.0 0.0 2.8 0.1 0.3 0.3 0.0 0.0 2.0 0.8 0.0 0.0 4.5 0.0 0.3 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.5 0.5 1.1 0.3 0.6 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.1 0.0 207.6 0.0 13.7 4.5 8.5 8.5 6.4 5.0 5.6 11.2 8.8 9.6 7.2 7.8 16.4 0.7 9.6 7.0 0.7 1.6 1.1 7.3 4.8 0.6 1.5 1.2 0.9 25.1 10.0 13.9 125.0 2.1 3.1 51.9 48.4 92.0 2.9 0.1 69.4 10.1 1.8 14.4 142.5 0.0 0.5 5.8 2.3 26.0 67.6 0.0 0.3 1.8 0.2 0.7 0.0 0.0 16.1 44.7 0.6 0.9 0.3 0.6 17.0 7.2 0.0 1.2 3.3 1.0 0.0 17.9 10.7 54.2 1.5 0.9 7.4 15.5 0.9 48.0 2.1 0.0 1.4 3.1 0.4 0.5 10.0 8.4 32.8 0.8 0.3 2.3 90.6 SMPX "Chisel, Csl, DFN6, DFNX4" ENSG00000091482 "Small muscle protein X-linked" Q9UHP9 X 21705978-21758116 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "heart muscle: 757.5;skeletal muscle: 1183.4;tongue: 1097.5" "Cell type enriched" "Detected in some" 22 "Cardiomyocytes: 807.6" "Group enriched" "Detected in many" 4 "head and neck cancer: 7.2;stomach cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "GAMG: 23.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA077360 Approved "Plasma membrane" NA NA 62000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA077360: AB_2732342" "unprognostic (7.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-1)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.39e-2)" "unprognostic (7.46e-2)" "unprognostic (5.27e-1)" "unprognostic (1.96e-2)" "unprognostic (3.97e-2)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (2.82e-1)" "unprognostic (8.38e-2)" 0.2 0.1 2.6 0.5 2.4 0.1 1.1 3.6 3.8 0.3 0.9 25.6 0.7 0.4 0.0 20.0 0.7 0.5 757.5 1.6 4.1 0.1 1.2 0.5 0.2 1.7 3.3 1.1 0.2 0.0 0.2 0.0 1.5 11.1 3.4 1.7 17.8 0.7 1183.4 0.5 4.1 12.6 1.3 0.1 7.2 0.2 5.3 1.5 0.2 1097.5 0.1 3.2 0.2 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 3.6 3.8 1.6 4.1 1.7 3.3 1.5 1.3 5.3 2.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 807.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.6 0.0 0.0 16.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 35.6 9.5 0.1 0.3 0.0 0.0 0.3 0.1 2.1 0.1 0.0 SMYD1 "BOP, KMT3D, ZMYND22" ENSG00000115593 "SET and MYND domain containing 1" Q8NB12 2 88067825-88113384 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "heart muscle: 160.4;skeletal muscle: 493.6;tongue: 301.3" "Cell type enriched" "Detected in some" 27 "Cardiomyocytes: 208.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.9;stomach cancer: 1.6" "Region enriched" "Detected in some" 4 "basal ganglia: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HSkMC: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA062282 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA062282: AB_2684736" "unprognostic (1.93e-2)" "unprognostic (2.49e-1)" "unprognostic (4.09e-2)" "unprognostic (8.51e-3)" "unprognostic (2.74e-1)" "unprognostic (3.91e-1)" "unprognostic (8.81e-3)" "unprognostic (1.40e-1)" 0.0 0.0 0.2 0.2 4.1 0.0 5.4 0.1 1.0 0.0 0.0 17.9 2.0 0.0 0.0 7.3 0.0 0.0 160.4 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 2.4 0.0 0.0 0.3 4.0 1.9 0.0 3.9 0.0 493.6 0.1 7.0 28.1 0.1 0.0 7.3 0.3 0.1 0.4 0.1 301.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.1 0.1 1.0 0.4 0.1 0.1 0.2 0.3 0.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.7 208.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMYD2 "HSKM-B, KMT3C, ZMYND14" ENSG00000143499 "SET and MYND domain containing 2" Q9NRG4 1 214281102-214337131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 198.8;skeletal muscle: 92.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 148.0;Cytotrophoblasts: 168.7;Early spermatids: 134.5;Extravillous trophoblasts: 110.5;Late spermatids: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029023 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Mitochondria "HPA029023: AB_10601605" "unprognostic (8.53e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (5.98e-2)" "unprognostic (1.00e-2)" "unprognostic (8.55e-2)" "unprognostic (2.53e-2)" "unprognostic (2.24e-2)" "unprognostic (1.72e-2)" "unprognostic (1.90e-3)" "unprognostic (1.65e-1)" "unprognostic (9.44e-2)" "unprognostic (2.77e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.65e-1)" "unprognostic (4.92e-2)" "unprognostic (8.10e-2)" "unprognostic (6.37e-2)" 15.5 15.0 12.4 9.0 13.0 8.9 18.7 13.5 32.1 12.2 17.8 12.9 13.8 9.5 7.5 18.1 27.6 9.3 198.8 14.6 16.1 20.4 26.2 18.1 13.5 14.7 16.7 12.0 19.1 6.9 17.1 27.3 14.2 12.1 14.3 14.3 13.7 8.1 92.4 11.4 12.6 10.1 14.5 15.1 19.2 24.3 14.4 22.6 20.3 4.2 14.2 11.8 10.1 14.4 64.4 14.5 22.7 16.8 21.7 37.7 102.4 36.6 28.8 41.8 46.6 68.3 52.0 34.6 36.7 39.8 19.7 28.9 21.3 63.5 36.8 28.3 29.8 10.1 30.0 46.7 19.9 47.6 7.4 42.9 31.2 30.5 21.6 27.2 32.1 29.5 35.0 7.5 36.4 33.5 32.6 26.1 21.3 32.4 26.3 20.6 59.9 27.8 33.9 45.2 23.7 55.3 28.9 95.0 73.3 47.8 75.5 30.1 38.6 32.9 49.6 18.0 55.2 33.2 13.0 39.2 43.1 35.1 37.8 15.8 10.0 14.4 15.0 5.7 17.8 15.4 22.5 19.9 9.5 7.5 19.3 18.0 0.9 29.2 1.9 6.4 26.7 13.0 12.4 13.0 13.5 32.1 14.6 16.1 14.7 16.7 14.2 14.5 14.4 14.4 10.5 19.2 9.7 7.5 13.7 20.6 16.5 40.0 25.0 8.7 16.8 19.9 148.0 24.3 17.7 3.7 0.0 168.7 12.2 10.0 31.3 34.3 134.5 48.7 9.9 15.6 4.2 8.6 60.7 20.0 110.5 11.1 11.7 17.4 3.8 27.9 17.2 20.3 38.4 15.2 26.9 13.4 14.2 21.5 10.6 120.4 11.8 11.4 16.0 22.5 11.7 28.1 9.2 7.1 10.3 26.1 11.7 3.8 16.4 16.1 21.9 34.6 69.6 8.0 13.1 6.8 16.7 13.9 39.6 28.9 18.0 85.9 16.8 30.0 19.3 10.9 SNAI3 "SMUC, Zfp293, ZNF293" ENSG00000185669 "Snail family transcriptional repressor 3" Q3KNW1 16 88677688-88686507 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 31.3" "Cell type enhanced" "Detected in some" "dendritic cells: 19.7;granulocytes: 9.5;Kupffer cells: 14.6;Langerhans cells: 9.3;Macrophages: 9.4;NK-cells: 17.5;Plasma cells: 14.0;T-cells: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "NB-4: 18.2;RPMI-8226: 28.6" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Not detected" "Not detected" HPA071127 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA071127: AB_2686346" "unprognostic (1.03e-2)" "prognostic favorable (1.39e-4)" "unprognostic (2.20e-2)" "unprognostic (6.19e-4)" "unprognostic (3.05e-1)" "unprognostic (2.85e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (3.24e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.58e-4)" "unprognostic (9.09e-2)" "unprognostic (1.62e-1)" "unprognostic (8.46e-2)" "unprognostic (6.57e-2)" "unprognostic (1.11e-1)" "unprognostic (7.47e-2)" 0.7 0.5 1.5 2.4 2.4 1.8 0.4 0.0 3.3 0.6 0.0 1.2 1.5 0.6 0.3 0.6 0.8 1.0 2.4 1.9 0.0 0.7 0.8 2.2 3.9 2.1 0.0 0.5 1.7 1.5 0.7 0.1 3.7 0.8 0.3 0.3 1.2 0.2 31.3 0.6 3.7 0.2 0.0 6.9 3.3 0.9 0.0 0.8 0.9 7.3 2.6 1.4 0.5 0.0 0.3 0.9 0.3 1.3 0.0 0.0 0.6 0.3 0.0 0.0 0.1 3.5 0.3 2.3 0.5 0.0 0.8 0.8 0.3 0.2 0.0 0.4 1.2 1.1 0.1 1.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.5 2.1 4.3 0.0 3.2 0.2 18.2 0.4 0.3 0.4 3.9 0.3 28.6 0.0 0.4 1.7 0.2 0.7 0.0 0.2 0.4 1.2 2.2 0.3 0.1 1.0 0.2 0.0 0.7 4.2 4.0 0.3 4.9 0.5 5.2 14.1 48.5 10.2 5.3 18.8 7.8 16.7 9.8 16.7 6.1 10.0 6.4 30.9 1.1 1.5 11.9 21.4 10.9 1.5 2.4 0.0 3.3 1.9 0.0 2.1 0.0 3.7 0.0 0.0 0.0 0.3 3.2 0.0 2.0 8.5 0.5 0.1 0.4 0.0 0.2 0.4 0.5 2.0 0.0 0.7 0.0 0.0 0.0 19.7 0.0 1.9 0.1 0.0 0.6 0.0 0.4 0.0 0.4 6.4 0.4 0.5 0.2 0.5 0.1 9.5 0.0 0.4 0.1 6.9 0.0 3.7 0.1 2.0 14.6 9.3 0.3 0.0 9.4 5.4 0.0 5.3 0.1 17.5 1.0 1.9 0.1 1.1 0.4 14.0 0.1 0.0 0.2 1.0 0.9 0.0 0.7 0.4 0.0 1.5 0.2 0.3 0.1 14.0 0.0 0.3 0.1 SNAPC5 SNAP19 ENSG00000174446 "Small nuclear RNA activating complex polypeptide 5" O75971 15 66490135-66497780 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 118.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024379 Uncertain Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA024379: AB_2671552" "unprognostic (4.43e-2)" "unprognostic (1.53e-3)" "unprognostic (4.39e-3)" "unprognostic (4.56e-2)" "unprognostic (3.49e-2)" "unprognostic (2.31e-1)" "unprognostic (1.06e-1)" "unprognostic (8.07e-2)" "unprognostic (1.12e-2)" "unprognostic (3.39e-2)" "unprognostic (3.13e-1)" "unprognostic (6.28e-2)" "unprognostic (1.64e-2)" "unprognostic (1.25e-1)" "unprognostic (2.21e-1)" "unprognostic (9.40e-2)" "unprognostic (5.69e-2)" 22.4 26.0 31.5 17.3 32.0 15.0 21.8 33.3 40.5 20.4 34.9 32.9 15.7 25.1 41.1 15.8 22.9 13.9 42.3 32.4 34.2 33.0 35.1 19.4 23.8 31.8 33.2 20.9 22.3 32.9 27.4 18.2 33.0 24.4 18.7 28.6 18.5 22.1 60.1 15.1 19.7 20.2 31.3 22.8 23.2 32.6 33.3 21.3 26.9 27.5 22.3 27.3 17.8 33.6 17.3 54.2 23.4 50.4 27.8 26.5 26.3 19.4 27.1 24.5 17.2 31.1 40.3 21.2 44.6 22.6 22.4 35.5 62.6 27.0 27.3 37.7 34.6 28.5 56.2 47.0 33.0 72.8 30.2 22.4 33.2 20.2 49.9 16.5 17.0 38.6 92.8 43.3 18.2 37.7 35.0 28.5 24.3 72.2 23.0 33.8 23.0 79.5 30.2 24.9 30.1 24.3 22.1 44.0 86.5 49.4 40.5 48.7 17.8 23.0 43.2 25.1 33.3 30.2 56.5 36.3 23.7 93.2 47.9 32.5 26.7 34.7 33.6 43.3 42.3 43.8 40.4 45.2 22.6 32.7 53.5 45.3 13.0 49.2 47.0 39.1 50.7 32.3 31.5 32.0 33.3 40.5 32.4 34.2 31.8 33.2 33.0 31.3 33.3 33.6 24.2 22.4 19.2 13.1 20.1 9.4 16.2 33.0 8.6 13.7 19.1 24.5 53.1 18.6 27.9 27.6 10.4 33.4 23.9 13.9 84.1 27.1 118.4 28.4 18.1 23.3 13.9 17.9 8.6 47.6 26.6 22.5 11.7 14.0 19.6 25.1 12.5 48.2 47.2 18.5 10.2 18.1 38.7 18.2 11.8 98.3 26.8 20.3 26.6 8.4 33.2 22.2 43.3 8.5 13.6 27.9 11.1 27.8 19.2 28.7 17.1 79.7 46.4 19.7 0.0 21.3 25.5 92.3 40.7 15.7 9.7 22.3 26.0 30.0 18.6 19.2 SNRNP25 "C16orf33, U11/U12-25K" ENSG00000161981 "Small nuclear ribonucleoprotein U11/U12 subunit 25" Q9BV90 16 53828-57669 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.6" "Cell type enhanced" "Detected in all" "Distal tubular cells: 156.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 219.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041183, HPA044248" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041183: AB_2677353, HPA044248: AB_2678873" "unprognostic (7.87e-2)" "prognostic favorable (1.95e-4)" "unprognostic (6.04e-2)" "unprognostic (5.03e-2)" "unprognostic (2.04e-1)" "unprognostic (5.99e-2)" "unprognostic (1.17e-1)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (8.99e-2)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.16e-5)" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (1.45e-1)" "unprognostic (6.03e-3)" 15.2 29.3 80.7 20.6 81.4 32.7 16.1 95.2 98.3 14.0 74.4 27.2 12.9 15.9 16.3 20.1 16.0 10.4 85.3 81.7 81.0 25.0 39.2 10.8 32.6 86.3 82.7 19.8 19.7 24.6 30.7 8.7 87.0 19.8 17.5 12.4 22.9 13.8 131.6 10.9 16.5 15.1 81.8 19.0 27.6 11.0 88.0 22.5 17.7 84.5 31.2 17.2 11.9 80.1 50.1 111.2 60.7 70.8 21.2 24.9 29.5 41.4 26.5 90.7 76.1 150.4 47.5 157.3 48.3 34.2 48.6 50.4 111.8 76.2 69.2 57.3 87.8 91.6 155.3 152.9 22.4 168.9 103.9 32.1 27.0 80.8 22.4 19.6 49.6 93.5 139.2 36.5 52.2 236.5 89.5 70.0 72.8 88.4 54.5 141.9 64.6 186.9 48.6 34.7 66.2 42.9 93.4 119.8 20.7 59.0 77.5 80.8 39.3 40.0 49.6 51.8 67.2 37.6 96.9 248.2 21.3 89.5 62.3 15.1 25.5 93.3 14.9 40.3 17.9 74.3 15.1 17.9 49.6 75.1 15.9 16.3 17.2 22.5 35.9 219.7 26.1 23.2 80.7 81.4 95.2 98.3 81.7 81.0 86.3 82.7 87.0 81.8 88.0 80.1 16.5 12.8 14.3 6.8 53.4 18.6 27.2 39.5 14.8 17.9 48.1 51.9 113.0 18.6 29.3 33.1 4.2 54.6 62.3 30.9 156.5 41.6 3.0 27.3 23.8 18.9 44.0 58.5 9.9 51.4 63.3 29.3 30.1 36.9 4.5 62.3 16.4 67.5 114.5 11.8 9.8 34.5 69.2 26.4 59.8 6.5 21.5 36.2 62.2 5.6 94.3 89.0 32.0 4.5 6.5 31.0 44.8 29.7 65.9 31.5 24.0 87.6 53.2 14.5 6.6 29.4 35.7 33.7 44.8 35.8 21.9 26.1 22.4 105.0 53.5 27.7 SNRPC "U1-C, Yhc1" ENSG00000124562 "Small nuclear ribonucleoprotein polypeptide C" P09234 6 34757505-34773857 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 384.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034338, HPA042419, HPA055490" Supported Enhanced Nucleoplasm NA NA 320000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB034338: AB_2295245, HPA042419: AB_2677989, HPA055490: AB_2682833" "unprognostic (1.84e-1)" "unprognostic (3.73e-2)" "unprognostic (1.59e-1)" "unprognostic (2.32e-3)" "unprognostic (1.45e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (5.65e-4)" "unprognostic (1.48e-2)" "unprognostic (6.16e-2)" "unprognostic (1.16e-3)" "unprognostic (7.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (8.20e-5)" "unprognostic (4.39e-2)" "unprognostic (8.64e-2)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" 71.7 73.9 68.4 67.7 73.7 176.7 74.2 73.1 84.5 67.0 75.3 78.5 73.1 83.5 63.1 85.5 84.8 48.9 195.7 70.5 71.8 91.7 92.0 62.6 101.6 72.2 70.5 75.0 87.0 78.2 57.6 73.5 73.1 65.8 65.6 39.7 75.2 55.3 162.0 67.4 75.6 65.3 75.4 84.7 81.8 124.4 72.6 115.5 75.3 125.0 95.3 73.9 66.6 78.4 332.8 203.2 260.7 331.6 137.7 134.7 199.0 186.6 204.9 367.9 308.6 349.6 128.4 373.9 239.1 235.0 255.6 156.0 398.7 279.1 297.8 247.6 420.0 287.7 158.7 493.4 240.1 371.2 171.0 167.3 266.4 372.5 264.1 144.9 237.0 354.4 471.2 205.0 270.4 280.8 443.8 592.0 282.4 493.9 245.8 295.2 219.4 350.5 242.0 140.9 316.9 229.9 167.3 167.0 422.3 167.7 256.0 541.5 157.4 219.8 258.3 181.0 460.4 228.5 645.6 522.4 101.2 629.7 381.1 122.8 165.7 133.4 127.2 200.4 149.4 233.5 156.2 148.4 196.1 210.7 168.3 153.9 30.3 163.3 238.6 207.6 235.7 245.6 68.4 73.7 73.1 84.5 70.5 71.8 72.2 70.5 73.1 75.4 72.6 78.4 43.6 121.8 107.9 5.2 70.5 44.0 76.0 178.6 72.8 25.9 47.4 64.4 229.3 82.9 131.3 68.0 25.0 239.8 69.0 49.1 189.8 148.4 185.6 74.2 58.0 74.3 90.7 73.2 11.1 156.8 213.9 72.3 51.5 63.7 80.4 83.6 71.4 101.1 232.2 28.6 10.1 92.6 118.0 77.3 55.1 83.8 55.3 75.4 64.0 1.9 158.2 96.6 123.6 8.5 14.6 149.3 66.7 41.8 116.6 70.0 96.0 214.6 127.4 41.4 65.7 49.0 82.8 384.6 99.7 83.8 44.8 113.3 70.7 86.3 109.6 67.8 SNRPN "HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN" ENSG00000128739 "Small nuclear ribonucleoprotein polypeptide N" P63162 15 24823637-24978723 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 457.8;Horizontal cells: 333.1;Proximal tubular cells: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 789.5;SuSa: 505.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003482, HPA067842" Approved Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA003482: AB_1857337, HPA067842: AB_2685909" "unprognostic (9.91e-2)" "unprognostic (1.03e-3)" "unprognostic (2.79e-1)" "unprognostic (1.66e-2)" "unprognostic (3.71e-2)" "unprognostic (2.32e-2)" "unprognostic (1.08e-1)" "unprognostic (2.72e-2)" "unprognostic (9.44e-3)" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (6.59e-2)" "prognostic favorable (8.93e-8)" "unprognostic (4.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" "unprognostic (6.74e-2)" 54.8 181.8 453.6 46.5 472.5 36.5 69.4 441.8 553.5 112.3 351.6 87.3 36.4 65.2 332.5 44.0 121.9 141.2 483.2 474.3 510.7 192.0 69.9 76.4 93.5 454.7 440.5 147.8 111.8 243.4 375.5 37.4 458.5 174.2 34.8 161.7 125.7 147.6 232.7 38.2 62.5 59.0 415.8 85.2 88.3 60.7 467.8 136.8 300.4 272.4 80.6 82.5 66.4 470.8 1.0 148.6 260.8 180.1 153.4 69.5 1.1 46.9 100.0 31.7 57.8 138.1 69.1 0.2 91.6 118.7 47.9 26.7 0.0 142.7 18.2 81.1 0.1 89.3 90.1 151.5 181.8 107.1 76.8 132.6 60.6 69.4 81.8 213.2 95.7 189.8 24.8 0.4 183.3 0.0 216.9 1.5 789.5 0.0 63.0 113.3 97.8 0.5 172.3 222.2 155.7 147.1 0.7 3.6 174.0 505.7 93.6 271.3 62.3 79.2 78.2 0.3 28.8 215.3 126.9 140.4 65.9 72.9 59.8 234.8 68.0 106.8 313.9 74.2 355.8 371.9 385.3 359.0 65.2 342.1 508.0 420.8 18.5 291.2 77.4 531.9 434.4 581.7 453.6 472.5 441.8 553.5 474.3 510.7 454.7 440.5 458.5 415.8 467.8 470.8 57.1 9.6 45.5 0.0 106.2 2.2 102.6 4.4 53.5 171.0 77.1 96.5 185.2 218.8 23.0 178.4 52.1 1.0 157.6 10.0 457.8 150.0 92.9 36.8 27.9 57.7 142.7 31.1 0.0 81.6 1.2 54.9 27.5 24.5 62.7 136.9 63.1 31.9 62.7 333.1 0.0 34.5 6.1 28.9 2.5 111.3 77.3 38.1 0.0 0.0 43.8 210.3 115.4 0.0 0.0 61.5 33.7 116.6 86.7 110.6 38.7 300.2 26.9 112.3 52.6 61.5 65.0 67.9 54.0 22.1 1.7 1.6 104.2 110.4 23.6 65.1 SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659666-31668931 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1645.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 3357.9;Proximal tubular cells: 3285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 44900000 50000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Plasma membrane, Cytosol" "CAB008670: AB_1623312, HPA001401: AB_1080132" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (4.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.39e-1)" "unprognostic (9.59e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (5.28e-2)" "unprognostic (9.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (3.26e-2)" 257.6 597.1 558.0 118.4 577.4 166.4 233.5 605.2 805.1 206.6 586.6 251.0 360.3 179.5 228.4 221.1 197.1 206.0 477.3 575.1 619.9 483.2 1645.6 153.9 169.6 619.8 604.6 302.1 117.1 210.6 236.7 155.8 653.1 203.9 180.5 248.6 160.5 204.2 428.0 152.1 266.7 136.6 588.1 147.5 210.4 132.1 585.8 165.7 197.4 355.9 151.7 232.1 220.6 634.7 526.8 451.4 309.2 312.8 407.3 282.1 257.8 430.2 258.0 291.3 217.4 593.6 326.0 628.2 441.2 405.8 517.7 186.1 453.3 320.6 239.9 463.3 540.0 1008.2 579.5 866.3 267.4 451.7 363.1 294.8 240.6 406.5 225.2 327.9 331.2 469.0 704.4 773.2 357.4 860.0 489.0 454.5 466.1 830.0 475.4 413.0 622.0 981.4 579.4 320.5 335.9 281.4 805.1 419.4 438.3 279.2 484.3 393.4 387.4 222.9 489.2 304.7 322.0 583.4 1374.2 741.8 455.7 654.3 301.9 204.2 159.7 194.0 313.4 234.0 365.3 427.1 509.2 402.4 212.8 310.1 521.8 412.1 37.8 241.4 465.4 240.6 746.0 474.5 558.0 577.4 605.2 805.1 575.1 619.9 619.8 604.6 653.1 588.1 585.8 634.7 319.8 294.9 175.1 38.2 248.1 491.4 672.7 479.2 319.8 226.6 264.1 352.9 721.0 527.6 294.7 391.8 47.9 703.4 250.2 703.5 1631.7 426.3 277.0 410.7 241.2 261.0 288.4 898.8 39.7 807.3 574.9 365.8 198.8 216.3 220.0 278.9 318.1 3357.9 363.3 282.7 45.5 402.7 366.2 220.0 318.5 952.2 521.9 224.2 419.8 29.0 313.1 598.5 239.0 28.6 68.7 322.8 600.9 528.1 178.2 567.0 1158.3 3285.9 638.3 216.5 440.4 313.6 404.5 211.7 506.3 379.9 349.8 725.9 423.1 470.3 593.6 497.7 SORBS2 "ARGBP2, KIAA0777" ENSG00000154556 "Sorbin and SH3 domain containing 2" O94875 4 185585444-185956652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 575.3;thyroid gland: 277.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 557.8;Cone photoreceptor cells: 771.5;Excitatory neurons: 397.4;Rod photoreceptor cells: 815.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 241.1;TIME: 133.1;WM-115: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (3.30e-2)" "unprognostic (5.09e-2)" "unprognostic (1.20e-1)" "prognostic favorable (6.07e-5)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" "unprognostic (8.30e-2)" "unprognostic (1.72e-1)" "prognostic favorable (3.10e-6)" "unprognostic (1.26e-1)" "unprognostic (2.42e-1)" "unprognostic (2.79e-3)" "unprognostic (2.51e-2)" 27.4 166.6 32.3 11.5 62.5 0.1 38.9 0.0 40.3 31.8 14.1 85.9 10.5 17.6 34.3 36.5 37.0 29.0 575.3 38.0 2.1 32.4 126.5 19.2 5.3 16.1 0.9 17.6 117.3 100.5 29.1 69.0 18.2 56.1 25.9 156.1 74.4 62.3 6.9 8.1 16.1 31.6 1.9 26.2 40.5 3.0 2.8 31.1 277.6 12.8 11.3 50.1 16.3 26.7 0.4 0.5 241.1 0.2 33.6 59.4 12.0 0.5 0.2 0.0 0.6 6.8 19.4 0.0 25.8 2.2 1.6 0.0 0.0 9.1 0.2 0.1 3.6 3.8 18.4 16.0 0.0 0.0 0.2 22.0 2.7 37.1 2.9 31.7 44.8 6.7 0.1 0.2 2.7 0.0 0.0 0.7 23.4 0.0 0.0 23.9 0.0 0.2 32.8 5.9 30.2 9.0 0.0 0.1 14.9 23.3 7.3 0.0 133.1 18.2 2.4 0.3 9.4 0.3 0.4 0.3 39.3 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.3 62.5 0.0 40.3 38.0 2.1 16.1 0.9 18.2 1.9 2.8 26.7 71.1 22.4 41.4 18.9 2.4 6.5 18.5 44.1 21.6 99.7 81.4 45.6 557.8 228.8 85.5 64.4 771.5 12.8 1.9 8.5 5.9 166.1 3.2 80.8 4.0 69.6 41.9 5.3 397.4 110.1 2.6 30.7 30.1 75.3 2.5 102.4 26.7 206.6 1.6 5.0 247.3 14.0 61.1 4.1 8.0 6.9 5.6 2.5 19.6 150.9 3.1 265.7 12.3 204.1 7.2 57.7 27.1 3.8 5.3 25.8 15.8 25.8 149.3 815.8 118.3 4.4 297.8 0.3 1.4 12.4 5.5 10.9 1.8 13.2 26.8 19.3 SPAG7 "ACRP, FSA-1, MGC20134" ENSG00000091640 "Sperm associated antigen 7" O75391 17 4959226-4967817 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 305.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024032, HPA052394" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA024032: AB_1857410, HPA052394: AB_2681810" "unprognostic (7.10e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-2)" "unprognostic (1.24e-2)" "unprognostic (1.46e-2)" "unprognostic (2.92e-1)" "unprognostic (8.90e-2)" "unprognostic (9.83e-2)" "unprognostic (8.35e-2)" "unprognostic (1.27e-1)" "unprognostic (8.39e-3)" "unprognostic (1.96e-1)" "prognostic favorable (5.79e-5)" "unprognostic (4.66e-3)" "unprognostic (5.51e-2)" "unprognostic (7.07e-3)" "unprognostic (2.72e-2)" 51.1 56.1 55.4 37.5 56.0 46.0 48.3 58.5 63.5 50.5 56.0 67.1 37.1 67.1 41.0 52.0 68.2 38.0 156.7 56.4 57.4 84.0 69.7 46.0 44.7 58.8 56.1 42.9 45.5 69.3 38.4 52.3 59.4 45.8 38.2 47.6 48.0 40.5 305.3 48.0 45.4 50.3 56.6 51.7 56.6 35.6 58.5 47.2 56.1 215.5 41.7 54.0 47.6 58.8 41.8 90.7 116.9 65.4 79.8 115.5 67.5 80.9 91.8 77.8 59.5 53.7 53.3 52.9 116.6 100.5 54.2 58.6 59.3 123.9 35.1 77.5 52.6 57.6 74.5 75.3 111.3 32.1 82.1 127.4 87.9 66.5 123.9 118.6 99.4 66.9 39.0 53.2 96.2 66.9 58.7 71.2 66.8 58.0 29.0 61.4 74.1 38.3 135.7 52.1 32.8 64.6 68.7 27.3 68.2 59.9 59.2 50.2 96.6 52.4 34.0 26.1 67.2 46.5 40.3 32.5 101.4 45.6 69.1 96.0 88.3 82.6 82.3 72.6 89.7 97.2 77.1 77.9 103.9 81.1 95.5 84.0 23.1 67.3 73.7 105.9 95.0 91.0 55.4 56.0 58.5 63.5 56.4 57.4 58.8 56.1 59.4 56.6 58.5 58.8 40.6 57.7 52.6 11.1 54.6 55.3 103.0 252.0 52.3 62.0 62.9 66.3 135.8 77.2 125.4 99.3 45.9 183.5 61.1 82.0 324.8 161.6 23.0 63.1 49.1 64.2 57.2 33.7 7.3 144.1 183.5 66.1 40.8 48.1 73.4 68.3 70.6 72.4 139.3 92.5 8.1 73.5 156.6 64.9 88.9 21.9 46.0 65.6 104.9 2.8 221.0 89.7 97.9 7.1 12.0 128.8 82.8 42.2 39.4 98.7 116.4 239.3 127.4 69.7 72.3 53.5 70.1 55.8 50.6 52.8 50.2 230.8 52.2 89.5 74.6 105.2 SPATA20 "FLJ21347, SSP411, Tisp78" ENSG00000006282 "Spermatogenesis associated 20" Q8TB22 17 50543058-50555852 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 117.5" "Group enriched" "Detected in all" 15 "Early spermatids: 594.1;Late spermatids: 1543.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 60.1;MCF7: 59.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022023, HPA027144, HPA031442" Enhanced Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA022023: AB_1857417, HPA027144: AB_1857418, HPA031442: AB_10610557" "unprognostic (9.27e-3)" "unprognostic (1.90e-1)" "unprognostic (9.60e-2)" "unprognostic (9.74e-3)" "unprognostic (2.63e-3)" "unprognostic (7.23e-2)" "unprognostic (1.56e-1)" "unprognostic (3.07e-1)" "unprognostic (7.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.12e-3)" "unprognostic (4.93e-2)" "unprognostic (6.74e-2)" "unprognostic (1.75e-1)" "unprognostic (2.29e-1)" "unprognostic (2.66e-1)" "prognostic favorable (9.69e-5)" 10.3 36.8 25.7 7.2 24.6 4.4 10.5 25.5 33.2 16.9 30.0 14.8 10.0 18.0 9.7 10.1 13.7 12.9 33.3 24.2 27.6 18.6 17.6 8.9 6.4 26.9 28.0 21.1 22.0 17.0 11.7 6.4 27.5 17.1 6.4 3.2 17.7 11.2 18.5 8.6 10.8 8.3 26.0 14.1 22.0 117.5 33.1 2.3 22.5 18.4 3.8 14.6 10.3 24.8 8.8 39.4 4.8 25.7 7.9 22.7 6.0 14.9 24.2 9.2 7.3 29.1 12.9 9.2 38.4 13.9 8.9 7.0 1.4 6.3 4.2 14.4 5.3 7.4 9.5 60.1 27.8 2.4 17.1 33.3 8.8 4.7 13.0 17.9 11.6 2.4 0.7 16.8 5.5 59.3 0.0 2.1 3.1 19.0 18.0 4.4 6.9 2.9 35.4 39.5 4.5 11.3 13.0 12.1 17.0 5.6 21.0 1.1 19.7 9.8 22.2 5.6 3.7 31.8 14.0 0.2 14.9 1.4 6.9 0.0 5.0 1.0 1.6 4.5 1.9 2.8 1.2 1.1 8.3 1.7 1.5 1.7 0.2 7.3 3.4 1.6 0.8 3.7 25.7 24.6 25.5 33.2 24.2 27.6 26.9 28.0 27.5 26.0 33.1 24.8 12.6 6.4 5.0 17.3 14.0 10.7 15.1 13.4 25.6 5.3 13.3 17.4 32.5 20.0 13.1 23.9 4.2 17.3 9.8 32.6 27.4 35.6 594.1 13.0 13.2 11.7 37.9 6.1 10.3 39.0 10.3 23.5 66.8 23.2 17.7 38.5 10.8 26.7 34.6 11.8 9.5 28.4 16.2 23.6 14.8 1543.1 38.2 20.0 21.4 6.5 19.3 26.9 12.3 8.5 2.3 23.7 31.1 38.0 17.9 12.2 18.4 38.8 5.9 2.4 6.6 18.1 19.1 10.0 13.8 11.9 8.8 9.9 11.2 39.9 23.8 17.1 SPG7 "CAR, CMAR, SPG5C" ENSG00000197912 "SPG7 matrix AAA peptidase subunit, paraplegin" Q9UQ90 16 89490719-89557766 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "unprognostic (1.42e-1)" "unprognostic (1.72e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.22e-4)" "unprognostic (4.10e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.54e-1)" "unprognostic (2.33e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.56e-2)" "unprognostic (7.01e-2)" "unprognostic (1.44e-2)" "unprognostic (2.58e-1)" "unprognostic (1.71e-1)" "prognostic favorable (4.25e-4)" 29.8 44.8 19.3 7.0 18.8 8.2 27.9 21.3 28.6 31.5 18.5 33.3 9.9 31.8 4.0 28.2 26.4 6.8 52.3 19.4 18.3 32.4 47.0 24.9 8.9 19.7 18.6 39.0 31.9 13.8 38.7 5.9 20.3 31.2 8.1 9.9 29.0 9.7 56.7 31.3 35.5 9.0 16.9 34.1 31.1 31.9 18.7 10.5 53.1 31.0 8.0 30.1 26.9 20.0 11.5 28.3 17.3 26.6 33.2 24.2 10.9 27.3 24.6 21.0 10.4 23.0 22.3 16.5 32.5 20.1 16.2 30.5 21.5 24.4 14.7 11.7 25.3 11.4 12.0 43.4 16.2 5.5 10.3 15.2 20.1 12.8 14.1 27.9 25.6 22.0 23.1 5.5 21.7 21.0 14.4 22.5 21.9 23.8 21.4 31.8 26.2 10.8 15.9 17.3 16.4 10.5 44.9 8.3 9.5 15.2 22.6 17.0 33.7 13.9 17.2 12.0 12.2 13.7 19.8 12.8 17.7 19.8 17.7 4.5 2.5 3.9 2.7 2.4 2.6 1.6 1.7 1.3 2.8 3.4 3.1 2.0 2.9 3.7 1.7 2.3 1.8 1.0 19.3 18.8 21.3 28.6 19.4 18.3 19.7 18.6 20.3 16.9 18.7 20.0 53.9 48.1 49.4 39.2 45.6 15.9 27.9 30.1 44.9 57.8 31.2 37.2 45.8 22.8 41.5 35.0 95.9 39.9 47.6 42.3 19.6 40.0 66.0 50.5 41.7 49.9 37.2 27.3 58.5 25.8 28.8 35.9 67.2 54.1 21.5 95.3 51.0 38.1 32.2 40.4 53.1 43.8 30.5 34.8 21.8 22.1 42.9 35.2 21.4 35.6 42.6 30.5 51.5 87.0 46.2 39.5 39.5 33.4 43.5 29.5 68.2 23.8 37.7 73.7 6.6 36.9 36.2 57.5 36.5 36.7 18.0 25.9 45.5 68.3 51.0 28.7 SPHKAP SKIP ENSG00000153820 "SPHK1 interactor, AKAP domain containing" Q2M3C7 2 227979955-228181687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "brain: 78.3;heart muscle: 29.1" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 82.2;Excitatory neurons: 67.7;Granulosa cells: 33.6;Inhibitory neurons: 128.6" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "cerebellum: 78.3;cerebral cortex: 49.3;hippocampal formation: 41.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "BJ hTERT+: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042499, HPA048168" Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042499: AB_2678027, HPA048168: AB_2680296" "unprognostic (4.91e-3)" "unprognostic (6.46e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-2)" "unprognostic (2.95e-2)" "unprognostic (2.09e-1)" "unprognostic (1.01e-3)" 0.0 0.1 10.6 0.0 8.8 0.0 0.8 78.3 49.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 41.1 4.2 0.0 0.0 0.1 0.0 6.8 13.3 2.1 0.0 0.0 0.0 0.0 7.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.2 11.2 0.3 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 45.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 8.8 78.3 49.3 41.1 4.2 6.8 13.3 7.1 4.2 11.2 3.3 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 7.2 2.6 3.0 82.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 67.7 0.0 0.0 2.1 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 128.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 9.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 SPRYD4 DKFZp686N0877 ENSG00000176422 "SPRY domain containing 4" Q8WW59 12 56468578-56479708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 147.2;Proximal tubular cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053469 Uncertain Approved Nucleoplasm NA NA 7500 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA053469: AB_2682162" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (8.85e-5)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (3.06e-3)" "prognostic favorable (4.52e-4)" "unprognostic (5.59e-3)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (9.98e-2)" "unprognostic (1.27e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-1)" "unprognostic (3.44e-1)" "unprognostic (1.14e-1)" 1.5 3.7 1.6 1.6 1.4 2.8 3.1 3.2 1.9 2.0 0.7 2.5 2.0 2.0 3.0 3.1 2.0 1.5 3.3 1.4 1.6 3.7 20.5 1.4 1.8 0.8 0.8 2.4 6.0 2.5 3.7 1.2 1.0 2.6 3.2 3.4 2.7 1.7 4.1 2.4 2.2 1.7 0.5 2.3 2.5 1.5 1.3 1.4 2.7 5.1 1.7 2.3 2.1 1.2 2.1 2.7 2.3 1.8 2.0 1.3 3.1 1.7 1.7 3.5 2.1 2.5 3.6 2.6 2.2 2.2 2.4 3.5 2.0 2.9 2.2 1.3 4.1 3.8 3.1 3.8 1.9 2.6 3.7 2.9 1.9 2.5 2.1 1.9 3.6 1.8 2.1 11.0 3.0 3.4 1.3 1.9 1.5 2.4 3.1 1.6 1.7 5.4 3.8 2.6 2.3 1.1 3.3 3.9 2.6 1.4 6.6 0.8 1.7 1.5 2.8 2.2 1.4 1.8 1.1 0.9 1.2 2.2 1.9 1.0 1.0 0.5 0.7 0.7 0.8 1.0 0.7 0.7 0.9 1.0 0.7 0.7 0.7 1.2 0.9 1.3 0.3 0.7 1.6 1.4 3.2 1.9 1.4 1.6 0.8 0.8 1.0 0.5 1.3 1.2 4.4 0.0 7.4 2.0 7.9 4.8 16.2 24.8 10.2 13.2 14.1 12.7 17.7 18.6 16.2 22.0 16.7 38.3 5.8 17.3 54.8 26.6 1.4 4.0 7.5 8.9 17.5 19.1 0.9 21.4 24.3 8.1 14.8 9.8 10.2 10.7 10.0 147.2 20.8 16.8 1.6 14.6 28.5 12.2 2.3 1.1 9.0 6.4 5.4 1.9 11.1 10.2 8.2 2.0 2.2 18.5 10.1 10.5 6.3 10.8 19.5 101.5 5.9 17.8 0.0 8.1 8.6 5.1 10.2 22.2 5.3 36.0 4.4 30.2 16.4 19.8 SPTBN4 "KIAA1642, SPTBN3" ENSG00000160460 "Spectrin beta, non-erythrocytic 4" Q9H254 19 40466241-40576464 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.1;pituitary gland: 7.8" "Cell type enhanced" "Detected in some" "Astrocytes: 48.6;Bipolar cells: 65.2;Cone photoreceptor cells: 56.3;Excitatory neurons: 209.5;Horizontal cells: 74.0;Inhibitory neurons: 194.8;Oligodendrocyte precursor cells: 46.3;Rod photoreceptor cells: 64.2" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 1.8;Karpas-707: 2.5;SCLC-21H: 3.9;SH-SY5Y: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054481 Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli Nucleoplasm "HPA054481: AB_2682502" "unprognostic (1.97e-3)" "unprognostic (1.02e-1)" "unprognostic (5.65e-4)" "unprognostic (3.72e-4)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (2.62e-1)" "unprognostic (2.50e-2)" "unprognostic (3.19e-2)" "unprognostic (1.65e-1)" "unprognostic (1.78e-4)" "unprognostic (4.54e-1)" "unprognostic (2.55e-2)" "unprognostic (6.79e-2)" "unprognostic (1.42e-1)" "unprognostic (1.85e-2)" "unprognostic (2.02e-1)" 1.1 2.1 4.8 0.1 5.9 0.1 0.7 6.4 20.1 1.1 0.0 1.6 0.3 1.5 0.1 0.4 1.3 0.4 2.1 4.8 0.0 0.8 0.3 0.3 0.0 4.0 0.0 2.6 0.9 1.4 7.8 0.0 2.2 1.5 0.0 3.4 0.6 0.4 2.1 0.5 0.5 0.3 0.0 0.2 1.2 2.0 0.7 0.1 0.7 0.9 0.0 1.1 0.7 6.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.2 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.8 2.5 0.0 0.6 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.5 0.0 0.0 3.9 2.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 5.9 6.4 20.1 4.8 0.0 4.0 0.0 2.2 0.0 0.7 6.0 0.2 0.0 0.0 48.6 0.1 0.1 0.2 0.1 0.6 65.2 0.7 0.6 4.9 0.0 0.2 0.0 56.3 0.0 2.7 0.1 0.0 0.2 3.4 0.3 0.8 0.5 16.3 0.0 209.5 0.0 0.0 1.0 0.0 0.8 0.0 0.7 0.4 0.8 0.2 74.0 194.8 0.5 0.0 0.6 0.2 1.3 8.1 0.6 1.8 10.3 0.6 6.1 0.0 46.3 13.4 0.1 0.0 7.2 0.1 0.4 0.3 1.7 0.2 64.2 0.0 1.6 0.7 3.5 6.0 0.3 0.4 0.0 0.4 0.4 0.3 0.2 SPTY2D1OS SPTY2D1-AS1 ENSG00000247595 "SPTY2D1 opposite strand" A0A0U1RRN3 11 18588781-18610255 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 34 "testis: 487.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 7.5;Distal tubular cells: 23.5;Endometrial stromal cells: 6.9;Granulosa cells: 18.4;Proximal tubular cells: 14.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 4.4;HeLa: 7.6;Hep G2: 4.5" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.07e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-3)" "unprognostic (5.14e-2)" "unprognostic (6.61e-2)" "unprognostic (9.32e-2)" "unprognostic (4.44e-7)" "unprognostic (1.75e-1)" "unprognostic (1.39e-2)" "unprognostic (7.83e-2)" "unprognostic (5.36e-2)" "unprognostic (6.50e-3)" "unprognostic (5.41e-4)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" 0.9 1.8 1.4 1.4 1.5 0.9 2.7 3.2 2.9 1.7 3.8 1.5 0.2 2.0 3.7 1.3 1.6 1.2 1.5 1.4 2.6 2.0 0.7 0.8 0.7 2.2 1.7 2.4 1.1 0.9 1.6 1.2 1.9 2.0 2.3 3.5 1.7 1.4 1.5 14.1 1.0 1.3 0.9 1.2 0.9 487.5 1.8 0.4 1.7 0.3 0.8 0.9 1.3 2.7 0.5 4.4 1.7 2.3 1.5 2.3 2.1 0.3 0.5 0.9 1.0 3.4 1.2 0.8 0.2 0.4 0.9 0.9 0.0 0.0 0.0 1.3 1.6 0.5 7.6 4.5 0.2 0.6 1.3 0.9 0.3 0.2 1.0 1.1 0.9 0.0 1.2 0.3 0.3 1.6 0.1 1.6 1.2 1.1 2.7 0.1 0.5 0.3 1.8 1.8 0.4 0.2 1.6 0.1 0.0 0.6 0.9 0.0 0.9 1.6 1.3 0.8 0.1 0.0 0.2 0.0 0.6 0.9 1.1 0.2 0.3 0.6 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.5 0.2 0.1 0.1 0.3 0.2 1.4 1.5 3.2 2.9 1.4 2.6 2.2 1.7 1.9 0.9 1.8 2.7 2.8 3.2 3.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.5 6.0 0.0 0.0 1.3 5.5 0.0 1.0 1.5 0.0 23.5 3.2 0.0 4.9 6.9 1.1 0.0 0.0 0.0 5.0 1.1 1.8 0.0 3.9 0.0 18.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 14.3 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.5 0.8 2.1 0.0 0.0 SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 111.4" "Group enriched" "Detected in some" 4 "Distal tubular cells: 86.1;Proximal tubular cells: 202.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 17.5;HBEC3-KT: 8.9;hTERT-HME1: 12.4;SuSa: 14.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 17.1;hippocampal formation: 17.9;olfactory bulb: 7.5;pons: 8.0" "Secreted to blood" NA NA 2650000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.78e-2)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.81e-2)" "unprognostic (2.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (5.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.37e-3)" "unprognostic (9.78e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" 111.4 0.1 8.7 0.1 9.2 0.4 4.1 8.6 24.2 0.0 7.2 0.1 0.0 1.3 0.6 0.2 0.2 0.1 2.8 8.1 11.5 26.4 2.3 0.6 0.2 8.6 13.9 0.0 20.7 0.4 0.0 17.7 26.6 0.0 0.0 1.7 6.9 0.5 2.0 0.0 0.3 0.1 8.0 0.4 0.5 0.2 9.6 3.0 20.2 8.8 0.1 0.0 0.0 9.9 0.0 0.5 0.8 0.0 3.0 1.2 0.0 0.0 0.1 0.1 1.2 17.5 0.0 0.7 0.3 0.0 0.3 0.0 0.0 8.9 1.6 0.0 0.0 4.7 0.0 0.1 1.8 0.0 0.0 5.7 0.9 0.3 12.4 0.2 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 2.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 1.7 14.6 0.0 0.2 0.3 0.0 5.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.7 9.2 8.6 24.2 8.1 11.5 8.6 13.9 26.6 8.0 9.6 9.9 1.4 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 3.0 0.7 0.9 28.9 0.0 0.0 25.8 0.0 0.0 0.1 0.0 86.1 0.4 0.0 0.5 0.3 0.6 0.0 0.0 0.0 19.1 0.0 1.7 0.0 2.5 0.0 0.0 0.7 0.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 13.7 0.0 0.0 1.2 4.9 4.1 0.0 0.1 2.5 0.0 0.0 0.0 0.1 0.0 202.2 0.0 0.5 0.0 2.4 0.9 0.0 1.8 0.0 0.0 0.4 1.0 0.1 0.0 0.1 SRGAP3 "ARHGAP14, KIAA0411, MEGAP, SRGAP2, WRP" ENSG00000196220 "SLIT-ROBO Rho GTPase activating protein 3" O43295 3 8980591-9363053 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.1;retina: 14.8" "Cell type enhanced" "Detected in many" "Astrocytes: 201.8;Bipolar cells: 217.5;Cone photoreceptor cells: 273.1;Endometrial ciliated cells: 166.0;Excitatory neurons: 223.1;Horizontal cells: 228.8;Inhibitory neurons: 281.2;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.3;HBEC3-KT: 8.2;hTCEpi: 7.8;RT4: 10.9;T-47d: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036959, HPA044074, HPA078079" Enhanced Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA036959: AB_10672784, HPA044074: AB_2678799, HPA078079: " "unprognostic (3.63e-3)" "unprognostic (1.12e-3)" "unprognostic (7.61e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.53e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.70e-2)" "unprognostic (5.58e-2)" "unprognostic (1.18e-3)" "unprognostic (6.10e-2)" "unprognostic (3.77e-1)" "unprognostic (2.75e-2)" "unprognostic (6.39e-3)" 0.7 3.3 12.3 0.7 13.9 0.3 1.5 22.1 16.9 5.2 0.3 1.0 0.7 2.2 1.5 2.3 10.9 1.0 1.8 14.5 9.1 3.2 0.5 1.0 1.1 5.1 9.8 3.7 1.1 0.6 6.1 0.7 7.4 4.5 1.1 14.8 4.2 1.4 1.3 3.7 0.9 0.7 5.6 0.7 1.5 3.5 11.9 1.8 2.6 2.1 0.9 4.1 1.7 10.0 0.5 0.5 9.3 0.4 0.6 1.2 1.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.1 4.8 0.2 8.2 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 5.0 0.7 7.8 0.6 0.8 0.2 0.0 2.1 0.0 0.0 0.0 0.1 0.2 2.0 0.9 1.6 0.7 1.1 0.0 0.0 3.8 10.9 1.0 1.2 0.2 2.8 0.1 2.2 10.5 0.0 0.0 0.0 0.3 0.1 0.1 2.7 0.1 0.0 0.8 1.7 0.3 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 12.3 13.9 22.1 16.9 14.5 9.1 5.1 9.8 7.4 5.6 11.9 10.0 1.0 3.2 5.6 201.8 2.3 4.1 28.7 36.3 23.3 217.5 7.9 9.8 9.6 0.0 40.6 77.3 273.1 2.4 3.5 1.4 5.9 3.2 24.1 166.0 6.0 4.2 3.0 0.8 223.1 0.5 0.8 4.9 8.2 93.8 1.3 5.4 0.7 2.1 13.2 228.8 281.2 6.2 12.2 18.6 6.0 20.2 2.5 9.4 1.8 37.5 3.3 80.6 1.0 159.8 132.2 0.6 0.5 1.2 1.4 12.3 0.5 1.4 59.4 94.8 0.0 2.9 3.9 6.1 7.1 17.2 5.8 1.4 14.7 12.0 3.1 31.2 SRRM4 "KIAA1853, nSR100" ENSG00000139767 "Serine/arginine repetitive matrix 4" A7MD48 12 118981541-119163051 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "brain: 18.3;retina: 29.1" "Group enriched" "Detected in some" 11 "Bipolar cells: 330.4;Cone photoreceptor cells: 429.5;Excitatory neurons: 182.0;Inhibitory neurons: 322.2;Rod photoreceptor cells: 372.4" "Cancer enriched" "Detected in single" 7 "glioma: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 4.4;SCLC-21H: 3.9;SH-SY5Y: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052783 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA052783: AB_2681945" "unprognostic (2.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.40e-2)" "unprognostic (1.25e-1)" "unprognostic (1.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-1)" "unprognostic (1.61e-5)" "unprognostic (1.10e-2)" "unprognostic (1.75e-1)" "unprognostic (5.70e-3)" "unprognostic (2.23e-1)" "unprognostic (6.88e-2)" "unprognostic (1.61e-1)" 0.0 1.1 7.1 0.0 10.4 0.1 0.0 16.4 18.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 8.8 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 29.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.3 0.0 0.1 0.1 0.0 0.0 0.0 6.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 10.4 16.4 18.3 8.8 0.1 0.0 0.1 0.1 0.0 1.3 6.4 0.0 6.4 0.0 3.6 0.0 0.0 0.1 0.0 0.0 330.4 0.0 0.0 9.9 0.0 0.6 0.0 429.5 0.8 0.0 0.0 0.0 0.0 5.6 10.6 0.9 1.5 0.0 0.0 182.0 0.0 0.3 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 28.6 322.2 0.0 0.0 0.0 0.0 3.8 0.0 0.1 0.0 9.4 0.0 12.1 0.0 5.5 3.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 372.4 6.6 0.2 1.0 0.2 1.2 0.0 0.0 2.3 0.1 0.0 0.0 0.1 SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1078781-1080142 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.9;kidney: 2.9;pituitary gland: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Hep G2: 15.4;PC-3: 54.7" "Group enriched" "Detected in some" 5 "basal ganglia: 4.1;hypothalamus: 2.3" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA066503: AB_2685679" "unprognostic (2.16e-2)" "unprognostic (7.31e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (9.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.09e-2)" 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 6.9 0.3 1.5 2.9 0.0 0.0 0.0 0.2 0.3 0.0 0.3 0.0 7.3 0.0 0.1 0.7 0.0 0.2 1.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 54.7 0.0 2.1 0.6 0.0 2.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.3 1.5 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 12.2;brain: 17.0;parathyroid gland: 6.2" "Group enriched" "Detected in some" 5 "Excitatory neurons: 106.1;Inhibitory neurons: 75.5;Oligodendrocyte precursor cells: 32.2" "Cancer enriched" "Detected in single" 8 "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 24000 "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Midbody" "HPA043813: AB_2678683, HPA046771: AB_2679798" "unprognostic (3.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-4)" "unprognostic (2.99e-2)" "unprognostic (4.83e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.55e-2)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" 0.1 12.2 4.0 0.0 12.9 0.2 0.0 17.0 11.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 6.2 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 6.2 0.5 0.0 1.4 0.1 0.0 0.7 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.2 0.0 0.1 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 87.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 12.9 17.0 11.4 6.2 0.0 0.4 0.1 1.4 0.0 0.0 7.7 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 7.8 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.0 3.1 0.0 0.1 0.2 0.0 0.0 106.1 0.0 0.0 0.2 0.0 0.0 0.0 12.9 0.0 0.0 0.1 0.0 75.5 0.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 3.7 0.0 1.1 0.0 32.2 9.1 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.6 0.0 0.6 0.2 0.8 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.1 STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.7" "Cell type enhanced" "Detected in all" "Early spermatids: 520.2;Hepatocytes: 660.0;Intestinal goblet cells: 717.9;Late spermatids: 2055.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 617.7;OE19: 1316.9;SK-BR-3: 427.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 13000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA026661: AB_1857538" "prognostic favorable (6.92e-4)" "unprognostic (2.07e-1)" "unprognostic (8.03e-2)" "unprognostic (1.74e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "unprognostic (4.16e-1)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (4.24e-3)" "unprognostic (8.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-2)" "unprognostic (1.04e-1)" 11.8 178.2 35.1 17.7 37.6 10.3 62.1 39.2 41.8 71.9 40.9 180.6 48.5 27.3 102.9 52.0 26.4 59.5 72.5 33.9 34.1 50.1 709.7 37.7 14.5 38.0 33.0 31.0 212.6 73.2 36.2 40.2 38.2 86.2 188.1 18.7 94.5 30.9 66.7 62.6 66.0 26.7 29.9 20.2 266.9 184.3 34.4 15.6 47.9 157.9 21.8 24.5 41.1 35.7 51.2 15.3 7.7 28.7 9.8 9.6 98.3 5.6 26.2 17.3 17.3 209.8 36.7 4.4 16.7 19.2 42.3 31.8 23.4 46.8 20.2 28.3 9.0 5.9 11.1 217.6 35.2 1.6 10.0 6.6 127.0 19.1 26.7 47.2 17.8 10.0 12.1 21.5 3.9 617.7 4.8 11.1 3.4 1316.9 20.1 4.5 13.3 3.4 23.5 61.4 13.0 10.1 8.6 427.4 73.3 32.8 235.5 6.3 13.6 17.0 11.4 6.0 10.1 22.2 19.8 7.5 4.3 5.6 6.5 12.9 2.6 16.0 1.6 1.1 1.2 4.2 1.5 1.7 1.2 2.4 1.6 1.6 21.7 7.5 0.6 2.6 2.1 1.1 35.1 37.6 39.2 41.8 33.9 34.1 38.0 33.0 38.2 29.9 34.4 35.7 10.6 35.3 74.1 8.1 18.1 31.5 76.3 41.0 25.0 10.5 163.3 125.3 45.3 270.2 76.4 55.2 22.9 212.8 17.1 362.8 123.3 70.7 520.2 26.5 6.8 18.5 302.2 22.9 11.6 94.3 93.1 21.1 372.1 25.3 25.4 10.1 30.0 660.0 26.4 33.7 13.9 717.9 85.5 26.0 34.4 2055.8 26.1 12.3 16.0 5.6 7.7 64.4 7.2 8.0 11.8 93.9 398.9 25.2 13.3 150.9 73.5 58.0 34.5 16.6 6.6 11.3 19.6 101.2 22.7 30.2 55.0 352.2 15.6 7.7 440.7 132.7 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 49.3;testis: 51.8" "Cell type enhanced" "Detected in many" "Astrocytes: 213.8;Early spermatids: 98.8;Endometrial ciliated cells: 220.9;Late spermatids: 157.0;Oligodendrocyte precursor cells: 117.6;Respiratory ciliated cells: 155.3;Spermatocytes: 148.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 4.1;naive B-cell: 2.2" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in many" "Daudi: 23.0;hTERT-RPE1: 22.0;Karpas-707: 21.2;SCLC-21H: 22.9;U-251 MG: 24.3;U-266/84: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: AB_2683257" "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favorable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 1.3 8.1 6.7 2.0 6.6 1.3 0.5 8.5 4.9 5.6 49.3 8.3 3.3 12.0 11.3 2.7 42.3 5.1 16.2 6.1 10.1 10.2 0.4 7.1 2.0 14.7 15.6 13.4 6.5 23.1 24.1 0.1 13.3 6.4 1.5 15.6 2.1 11.5 3.9 0.2 3.4 9.3 12.0 1.5 6.0 51.8 12.8 3.8 20.0 6.0 2.2 3.4 1.7 8.3 0.0 3.4 15.4 0.0 0.0 0.0 0.0 3.0 3.1 7.0 6.2 2.2 0.0 23.0 11.5 0.6 8.7 0.0 6.9 2.5 6.0 0.0 18.9 0.0 4.2 5.6 2.5 13.4 0.0 1.1 0.0 0.2 0.0 22.0 0.5 11.2 0.0 21.2 0.3 0.0 0.4 0.0 11.2 0.0 0.0 8.8 2.2 14.3 6.1 0.0 22.9 6.2 0.0 0.0 0.1 4.3 0.0 1.3 0.0 0.0 10.6 0.2 24.3 5.1 21.2 0.3 6.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.7 0.0 2.2 0.0 0.6 0.0 0.1 0.0 0.4 0.1 0.2 6.7 6.6 8.5 4.9 6.1 10.1 14.7 15.6 13.3 12.0 12.8 8.3 0.1 19.2 14.5 213.8 6.2 0.0 1.3 1.9 0.0 20.7 0.1 0.3 37.8 8.6 27.5 20.2 70.9 0.1 1.4 0.2 3.9 9.5 98.8 220.9 5.5 1.8 9.1 1.7 12.0 4.9 3.3 5.0 6.1 17.8 1.3 29.3 0.4 0.0 0.3 1.7 15.4 1.6 6.1 0.0 0.0 157.0 4.4 0.6 0.0 23.4 0.0 31.0 0.0 117.6 19.7 4.4 0.4 17.0 5.2 0.5 3.6 13.5 155.3 77.4 0.0 0.2 2.7 148.3 26.8 0.2 0.0 0.0 1.3 6.3 3.5 0.0 STPG3 "C9orf173, FLJ40246" ENSG00000197768 "Sperm-tail PG-rich repeat containing 3" Q8N7X2 9 137251261-137253483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 42.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 3.3;RPMI-8226: 1.4;SK-BR-3: 1.2;T-47d: 2.0;U-266/70: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA044352 Uncertain Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA044352: AB_10965328" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (4.32e-3)" "unprognostic (4.72e-4)" "unprognostic (2.56e-1)" "unprognostic (1.22e-2)" "unprognostic (1.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.29e-1)" "unprognostic (3.93e-2)" "unprognostic (8.59e-4)" "unprognostic (2.09e-1)" "unprognostic (7.25e-2)" "unprognostic (2.65e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (7.95e-2)" 0.9 0.5 0.0 0.4 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.1 3.9 0.2 0.2 0.1 0.4 0.2 0.2 0.0 0.1 1.1 1.5 0.1 0.4 0.1 0.1 0.0 1.3 0.0 0.7 0.2 0.1 0.3 0.0 1.5 1.3 0.0 0.0 0.6 3.0 0.0 0.1 0.4 0.5 42.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.9 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.4 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.0 0.0 1.4 0.0 0.0 0.4 0.2 0.1 1.2 0.0 0.2 2.0 0.0 0.0 0.3 0.6 0.1 0.0 1.2 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20 related adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 412.8;Proximal enterocytes: 124.0;Proximal tubular cells: 217.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 188.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026549, HPA028520" Approved Uncertain Aggresome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol Aggresome "HPA026549: AB_1844779, HPA028520: AB_10604100" "unprognostic (6.34e-2)" "unprognostic (2.48e-1)" "unprognostic (2.63e-1)" "unprognostic (3.56e-3)" "unprognostic (4.04e-2)" "unprognostic (7.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-3)" "unprognostic (2.65e-2)" "unprognostic (6.21e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.08e-1)" "unprognostic (7.83e-2)" "prognostic favorable (4.45e-4)" "unprognostic (4.93e-2)" 29.9 53.2 24.1 8.9 26.3 80.9 16.8 26.2 30.8 10.6 22.4 27.6 37.0 13.2 17.4 17.0 10.4 14.3 38.0 25.3 26.2 73.3 104.9 10.6 14.5 27.7 25.9 14.1 17.6 6.2 17.4 19.7 27.3 11.1 30.3 40.5 13.9 7.7 109.0 8.4 42.9 10.2 26.7 13.7 9.1 15.8 25.6 11.4 17.9 69.5 11.6 9.7 9.3 30.2 12.6 21.5 36.2 47.0 58.5 73.8 25.6 25.6 43.4 34.9 51.6 29.6 11.9 0.1 16.0 40.7 42.4 12.6 35.8 23.9 62.7 14.9 30.1 15.2 9.6 62.9 43.9 18.4 16.7 62.5 21.6 43.7 39.0 63.5 26.5 28.5 33.4 5.3 188.5 6.8 17.2 31.1 49.2 11.7 22.6 22.8 14.5 9.6 29.2 9.9 6.0 29.3 17.6 13.1 76.8 66.0 6.7 34.4 25.7 20.6 16.1 26.6 19.3 21.1 39.0 5.8 35.8 8.2 20.5 5.5 12.9 16.3 9.2 14.4 8.3 28.8 12.2 13.4 17.2 35.8 15.5 15.6 2.6 29.0 13.1 7.7 16.4 15.8 24.1 26.3 26.2 30.8 25.3 26.2 27.7 25.9 27.3 26.7 25.6 30.2 5.0 9.6 4.2 17.0 20.2 2.2 6.8 6.5 11.4 13.8 24.9 10.8 27.8 28.6 6.1 14.7 83.4 51.0 6.3 40.9 39.2 12.4 3.9 7.5 7.4 5.6 16.9 412.8 20.8 15.4 27.6 13.6 6.6 10.2 5.7 12.0 7.9 94.6 19.2 11.8 19.8 22.6 8.2 16.9 5.2 8.1 10.8 13.5 16.0 15.0 14.8 19.6 7.2 26.7 26.0 9.0 35.2 3.8 10.9 10.2 124.0 217.8 5.3 19.1 6.6 21.7 6.6 45.0 46.7 15.2 1.4 27.9 8.9 26.8 25.0 9.1 SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Early spermatids: 256.2;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" 53.9 40.6 28.4 20.2 30.8 13.6 38.7 36.6 39.2 32.4 33.6 37.1 58.2 27.2 24.8 33.1 24.7 20.3 100.2 30.7 38.2 77.5 29.0 18.2 22.0 30.6 30.0 30.9 25.4 71.2 20.4 28.1 32.3 35.8 36.3 44.2 33.9 31.3 232.2 20.5 44.7 33.1 30.6 19.9 29.7 17.9 33.8 30.7 36.4 271.9 23.9 26.0 25.3 35.1 44.9 49.5 60.6 37.1 68.4 51.3 38.9 64.8 72.4 66.9 44.5 91.3 47.9 61.3 49.3 63.9 39.9 60.0 81.9 61.9 81.6 59.8 75.9 69.2 45.8 58.0 47.6 69.9 38.9 48.4 71.2 45.3 52.6 54.4 49.0 70.7 47.7 21.1 65.8 31.4 73.1 80.8 64.4 150.2 64.7 60.9 55.4 49.3 94.4 41.9 34.7 41.2 54.5 49.3 39.1 66.5 43.8 60.8 39.0 36.2 24.1 53.0 45.7 23.0 37.4 72.7 22.8 50.9 54.8 12.6 50.2 27.8 34.4 53.7 41.9 34.6 38.0 42.2 62.5 33.1 47.7 47.5 8.8 51.8 46.1 49.8 46.6 36.5 28.4 30.8 36.6 39.2 30.7 38.2 30.6 30.0 32.3 30.6 33.8 35.1 20.8 25.6 16.8 17.6 20.1 32.4 37.7 57.5 21.1 44.8 28.9 26.5 148.8 17.2 40.2 31.3 12.5 48.7 18.1 29.1 164.4 32.3 256.2 50.9 32.0 22.0 19.2 21.0 37.0 17.8 42.7 37.7 19.9 52.6 33.7 25.2 16.1 14.7 29.9 45.4 39.0 19.5 71.2 16.7 20.4 314.2 37.0 21.7 42.7 21.5 24.9 43.3 13.4 26.2 38.2 20.2 30.6 46.3 22.1 35.9 62.3 127.4 29.9 42.4 39.5 33.3 50.0 36.3 29.0 22.8 31.7 52.1 19.7 47.3 30.4 39.0 SUGCT "C7orf10, DERP13, FLJ11808, ORF19" ENSG00000175600 "Succinyl-CoA:glutarate-CoA transferase" Q9HAC7 7 40135005-40860763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 44.4;liver: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 76.0;Inhibitory neurons: 38.5;Oligodendrocyte precursor cells: 58.3;Proximal tubular cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HBEC3-KT: 43.9;LHCN-M2: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026698, HPA026704, HPA026705" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026698: AB_10600191, HPA026704: AB_10600230, HPA026705: AB_10601003" "unprognostic (4.66e-3)" "unprognostic (3.45e-2)" "unprognostic (2.06e-2)" "unprognostic (3.32e-3)" "unprognostic (5.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.14e-3)" "unprognostic (1.75e-2)" "unprognostic (2.61e-1)" "unprognostic (1.80e-1)" "unprognostic (5.27e-3)" "unprognostic (7.65e-2)" "prognostic favorable (3.93e-7)" "unprognostic (2.62e-2)" "unprognostic (3.38e-1)" "unprognostic (3.41e-3)" "prognostic unfavorable (2.53e-4)" 2.4 9.0 1.7 0.9 1.8 0.1 2.3 1.7 2.2 2.2 4.4 4.5 0.7 2.2 1.0 2.1 1.7 2.8 3.9 1.7 2.0 44.4 28.4 0.6 0.8 2.0 2.1 4.1 2.3 4.1 0.9 0.6 1.9 2.0 2.4 2.0 1.4 1.8 10.3 0.9 5.3 2.2 1.8 0.8 1.0 2.8 1.8 0.8 1.8 8.2 1.0 2.0 1.6 1.8 0.8 0.1 4.8 3.4 5.0 11.5 1.8 2.5 4.6 3.2 3.8 2.0 1.0 3.1 1.2 3.5 3.4 0.2 1.4 43.9 5.3 0.0 2.1 2.8 0.3 7.3 6.2 0.4 0.3 14.6 9.7 3.7 2.2 6.9 0.9 1.2 3.9 0.3 26.2 0.0 0.1 0.4 8.1 0.1 3.7 2.9 0.4 0.0 7.4 0.0 0.3 2.7 4.0 1.8 5.8 7.9 0.1 0.7 3.7 14.6 4.2 0.2 1.0 0.3 0.0 0.2 2.8 1.2 3.3 0.0 0.0 0.1 0.2 0.0 0.4 0.5 0.7 0.3 0.0 0.3 1.4 0.9 0.3 0.0 0.0 0.0 0.0 0.2 1.7 1.8 1.7 2.2 1.7 2.0 2.0 2.1 1.9 1.8 1.8 1.8 0.6 3.2 0.5 76.0 1.9 2.0 2.1 26.0 10.2 1.0 1.3 23.0 5.1 1.5 4.4 1.8 8.4 1.5 0.0 10.1 17.6 1.2 31.0 0.9 2.5 0.7 3.6 0.4 19.8 0.8 2.4 3.5 0.0 1.3 0.0 2.2 0.0 21.1 0.3 0.0 38.5 1.5 0.0 1.3 1.0 16.7 6.2 0.7 3.6 14.0 0.1 5.3 0.0 58.3 22.8 0.6 5.6 3.0 0.1 0.8 13.9 81.6 0.8 4.5 6.6 1.4 15.3 2.7 3.1 3.2 0.6 0.8 0.7 7.4 5.3 0.7 SUOX ENSG00000139531 "Sulfite oxidase" P51687 12 55997180-56006641 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 49.6;Proximal tubular cells: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 72.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038208, HPA038209" Approved NA NA 44000 "Cluster 52: Eosinophils - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038208: AB_2675892, HPA038209: AB_10672738" "unprognostic (1.72e-1)" "unprognostic (7.40e-2)" "unprognostic (2.04e-1)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (9.72e-3)" "unprognostic (1.71e-3)" "unprognostic (2.86e-3)" "unprognostic (3.27e-2)" "unprognostic (9.74e-2)" "prognostic favorable (6.28e-4)" "unprognostic (6.95e-2)" "prognostic favorable (4.77e-7)" "unprognostic (1.65e-1)" "unprognostic (1.89e-1)" "unprognostic (2.85e-2)" "prognostic favorable (8.32e-5)" 19.2 35.2 19.3 9.5 20.2 12.8 18.2 21.0 22.6 16.7 22.2 20.6 19.3 17.6 33.0 21.5 22.9 16.7 29.4 19.6 19.9 40.8 72.3 15.6 8.3 20.7 20.0 22.1 17.4 48.6 16.6 11.5 20.6 25.2 17.1 13.8 20.2 24.5 45.6 10.4 15.6 17.4 20.1 13.6 21.3 8.3 21.7 6.7 18.2 28.8 12.0 21.2 14.3 24.0 10.2 29.8 18.5 30.2 29.6 12.2 40.1 11.5 12.5 15.4 11.1 28.8 22.1 1.2 19.8 14.0 10.6 13.2 13.7 14.5 8.2 45.8 9.0 15.7 19.4 34.9 10.9 0.2 25.9 19.0 5.5 13.1 6.8 23.0 38.9 1.6 28.2 19.0 16.2 25.1 0.4 10.0 9.9 15.6 21.4 13.6 7.7 22.4 17.8 20.4 9.2 12.3 21.1 42.6 17.4 17.2 72.2 14.9 20.6 8.5 10.4 10.8 8.2 22.0 21.3 1.6 13.7 10.2 12.7 11.1 12.6 29.6 0.2 18.7 0.1 2.5 1.2 0.0 16.1 0.3 0.9 0.2 5.1 16.5 16.2 0.5 7.9 11.8 19.3 20.2 21.0 22.6 19.6 19.9 20.7 20.0 20.6 20.1 21.7 24.0 4.5 9.6 10.9 10.7 1.1 1.3 3.8 6.7 6.2 5.1 9.1 6.1 21.7 11.5 12.8 14.7 6.2 29.7 0.9 7.7 17.6 5.6 0.7 7.7 6.7 7.1 6.0 6.5 4.1 6.3 19.1 6.4 6.6 12.4 4.5 6.6 8.9 49.6 10.5 10.1 4.4 6.0 4.1 8.9 4.0 0.9 4.4 4.3 1.8 5.6 10.0 8.5 2.1 5.5 6.2 5.3 7.4 9.1 3.2 3.1 7.9 35.8 6.1 8.4 6.6 8.4 5.4 2.4 1.4 6.8 2.3 30.8 1.6 6.7 7.7 3.0 SVIL ENSG00000197321 Supervillin O95425 10 29457338-29736959 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 808.1;tongue: 581.5" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 204.9;Cardiomyocytes: 469.6;Peritubular cells: 260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 259.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 259.3" "Cell line enhanced" "Detected in many" "HaCaT: 146.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010878, HPA020095, HPA020138" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 210000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "CAB010878: AB_476685, HPA020095: AB_1857680, HPA020138: AB_1857681" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.06e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-2)" "unprognostic (4.12e-1)" "unprognostic (1.49e-1)" "unprognostic (4.28e-1)" "unprognostic (3.42e-3)" "unprognostic (1.55e-1)" "unprognostic (9.20e-2)" "unprognostic (2.38e-3)" "unprognostic (7.11e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (5.70e-5)" 26.4 13.4 3.7 22.7 3.9 37.2 22.6 1.3 8.9 45.8 2.5 314.5 14.8 116.2 24.1 92.1 55.5 52.0 165.0 2.2 2.7 15.4 10.4 22.9 12.6 7.0 4.1 83.3 18.5 31.8 8.5 17.9 4.4 70.3 37.1 10.3 40.6 100.0 808.1 26.9 60.1 107.0 4.4 7.6 77.6 11.7 4.9 19.1 35.0 581.5 10.8 173.2 40.3 5.2 71.4 27.9 12.4 5.4 32.1 84.4 22.1 12.6 24.1 4.3 4.7 34.4 63.1 2.4 43.0 4.9 31.9 146.8 8.6 25.6 5.2 1.4 17.6 0.1 33.6 19.9 21.4 8.0 1.5 72.7 24.5 44.2 19.1 71.9 69.6 14.7 0.1 0.4 6.7 19.9 7.7 4.0 7.0 27.8 15.1 15.5 32.1 0.9 40.2 20.1 18.1 14.1 12.3 1.4 34.3 39.8 12.9 7.9 46.3 21.9 23.4 94.4 34.4 0.6 0.8 0.3 64.5 14.0 65.4 43.4 12.1 58.2 11.1 14.0 10.9 0.6 11.2 7.6 7.3 1.0 17.1 10.9 259.3 14.6 29.6 3.0 4.3 3.7 3.7 3.9 1.3 8.9 2.2 2.7 7.0 4.1 4.4 4.4 4.9 5.2 31.3 48.1 30.5 2.3 3.7 70.2 108.0 41.1 204.9 11.7 36.6 67.1 469.6 18.6 53.5 38.6 25.0 29.7 11.3 39.7 7.9 94.1 4.0 26.3 65.8 61.1 23.9 1.7 8.3 42.3 18.5 68.1 7.7 43.6 10.1 35.7 32.2 11.8 10.4 5.0 43.9 31.3 28.5 7.5 45.7 6.8 109.6 25.3 28.4 146.1 16.7 30.6 13.4 28.1 6.6 63.4 40.2 260.7 3.3 131.8 18.4 10.8 42.2 15.0 46.0 90.6 92.9 6.5 11.1 103.8 60.0 24.8 14.6 27.9 39.2 98.3 SVOP DKFZp761H039 ENSG00000166111 "SV2 related protein" Q8N4V2 12 108907741-109021068 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 14.3;pituitary gland: 7.4;retina: 13.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 41.7;Early spermatids: 65.4;Excitatory neurons: 70.3;Inhibitory neurons: 75.8;Late spermatids: 121.5" "Group enriched" "Detected in some" 9 "glioma: 0.6;pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 2.8;RPMI-8226: 3.0;SCLC-21H: 1.5;SH-SY5Y: 1.3;U-266/84: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016573 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA016573: AB_2197027" "unprognostic (6.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (6.51e-3)" "unprognostic (2.18e-2)" "unprognostic (3.79e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "unprognostic (4.29e-3)" "unprognostic (3.07e-1)" "unprognostic (4.28e-3)" "unprognostic (3.94e-2)" "unprognostic (2.26e-2)" "unprognostic (6.17e-2)" 0.0 1.5 11.2 0.1 12.4 0.1 0.0 2.2 14.3 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 1.0 11.3 9.5 0.1 0.2 0.0 0.0 2.9 2.1 0.0 0.7 0.0 7.4 0.0 3.7 0.0 0.1 13.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.7 0.5 6.4 0.0 0.0 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 1.5 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 11.2 12.4 2.2 14.3 11.3 9.5 2.9 2.1 3.7 0.4 6.4 6.0 0.2 12.8 9.6 2.6 0.1 0.0 0.7 0.0 0.0 19.7 0.1 0.0 1.3 0.0 5.0 1.8 41.7 1.3 0.0 0.1 0.0 0.1 65.4 0.1 0.1 1.0 16.8 0.0 70.3 0.0 0.3 0.6 0.0 0.2 2.5 0.1 1.1 0.1 0.1 11.8 75.8 0.0 0.0 0.0 0.0 121.5 0.3 1.0 0.0 1.0 0.1 2.1 0.0 4.0 2.8 0.1 0.0 0.7 0.0 0.3 0.0 0.1 0.0 21.9 0.0 1.5 0.7 0.7 0.9 0.0 0.0 0.8 0.5 0.1 0.0 0.4 SYNDIG1 "C20orf39, DSPC2, FLJ14220, IFITMD5, TMEM90B" ENSG00000101463 "Synapse differentiation inducing 1" Q9H7V2 20 24469629-24666616 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.4;heart muscle: 26.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 157.4;Microglial cells: 472.2;Oligodendrocytes: 214.3" "Cancer enhanced" "Detected in many" "glioma: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 15.4;RH-30: 43.4;RPMI-8226: 43.6;SCLC-21H: 10.0;U-87 MG: 26.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044271, HPA059267" Enhanced Vesicles NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA044271: AB_2732515, HPA059267: AB_2683961" "unprognostic (9.33e-2)" "unprognostic (1.83e-2)" "unprognostic (2.17e-1)" "unprognostic (9.56e-2)" "unprognostic (5.03e-2)" "unprognostic (1.27e-1)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (4.69e-2)" "unprognostic (4.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.94e-2)" "unprognostic (7.75e-3)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.16e-6)" "unprognostic (1.40e-3)" 1.8 0.9 23.7 1.5 23.2 0.0 0.5 27.6 26.8 3.2 8.6 0.8 1.2 3.2 0.7 0.2 4.2 8.8 26.9 21.1 21.0 4.9 0.0 0.7 2.0 28.4 23.0 0.9 0.7 0.2 0.7 0.2 28.4 3.3 0.9 1.8 0.3 12.3 0.1 0.2 2.1 2.2 27.8 0.7 1.6 0.8 25.3 1.6 4.8 0.1 2.4 1.7 2.0 36.4 0.0 0.3 2.6 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 15.4 0.0 0.8 0.0 0.0 2.6 0.0 0.0 0.0 43.4 43.6 0.0 0.0 10.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.2 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 23.2 27.6 26.8 21.1 21.0 28.4 23.0 28.4 27.8 25.3 36.4 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.2 0.7 0.6 1.2 0.0 0.0 157.4 0.0 0.0 2.0 0.0 0.8 0.0 21.9 0.0 0.0 0.1 3.3 69.7 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 472.2 0.0 1.9 0.0 41.7 214.3 1.5 0.0 7.2 0.0 0.0 0.0 5.9 0.0 0.5 0.0 0.5 1.4 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SYNGR1 ENSG00000100321 "Synaptogyrin 1" O43759 22 39349925-39385575 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 19.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "dendritic cells: 44.7;monocytes: 38.9;T-cells: 30.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029673, CAB034277" Enhanced Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 6: T47d - Mammary gland" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB034277: AB_2255766, HPA029673: AB_10670430" "unprognostic (2.68e-3)" "unprognostic (1.84e-3)" "unprognostic (5.90e-2)" "unprognostic (8.51e-2)" "unprognostic (3.74e-1)" "unprognostic (5.98e-3)" "unprognostic (7.39e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.16e-1)" "prognostic favorable (4.98e-7)" "unprognostic (1.32e-3)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" "unprognostic (1.04e-1)" 9.9 24.6 73.2 4.9 84.9 92.9 14.7 64.7 121.8 36.2 25.3 26.7 5.9 22.1 11.6 37.3 23.5 11.3 57.0 84.7 37.5 26.2 5.3 8.6 7.5 35.1 37.9 72.7 28.0 29.8 15.2 6.5 36.5 29.6 4.3 73.0 45.1 18.0 29.0 51.8 11.8 13.2 6.3 10.6 16.6 19.8 58.4 3.5 11.6 26.4 9.9 25.6 34.9 67.1 5.4 9.6 17.3 31.1 1.7 4.4 7.5 23.2 40.8 29.2 26.9 2.1 0.6 0.2 5.3 6.1 3.3 7.6 11.8 0.5 8.8 0.1 36.6 0.4 0.8 1.0 4.9 1.6 10.5 6.7 1.8 7.9 0.0 20.7 1.4 6.8 11.0 0.7 4.6 12.5 4.8 4.5 3.6 4.8 18.7 14.0 0.0 1.5 0.9 15.0 27.1 5.5 6.1 25.1 23.7 7.1 36.9 27.3 0.5 0.0 19.6 0.3 0.1 6.4 0.2 15.2 0.8 30.2 31.6 0.6 38.9 0.8 30.8 11.8 1.7 5.8 1.1 9.1 44.7 4.2 1.3 15.3 1.7 5.1 0.6 33.1 0.2 18.0 73.2 84.9 64.7 121.8 84.7 37.5 35.1 37.9 36.5 6.3 58.4 67.1 8.9 9.6 1.1 28.4 21.0 30.3 73.6 33.8 39.3 112.9 61.4 73.0 73.6 75.8 31.4 66.2 27.1 25.0 52.5 0.1 15.6 57.2 40.0 14.3 24.4 9.5 0.0 92.9 57.1 12.3 14.4 44.6 1.5 18.5 2.5 49.0 12.1 5.9 14.2 47.1 47.1 0.3 12.2 20.0 13.8 87.9 133.3 11.7 140.5 20.6 10.1 46.8 91.6 39.7 18.7 21.7 1.1 119.2 23.2 36.4 0.1 9.3 7.5 38.6 19.7 46.8 30.6 62.8 14.7 57.1 37.4 13.1 21.2 131.6 0.4 80.2 SYNPO KIAA1029 ENSG00000171992 Synaptopodin Q8N3V7 5 150601080-150659207 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 369.6;skeletal muscle: 1296.3;tongue: 502.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 264.7;Distal enterocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Cell line enhanced" "Detected in many" "BEWO: 88.4;EFO-21: 72.8;HUVEC TERT2: 72.7;TIME: 178.0;U-87 MG: 152.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033265, HPA034631, CAB037325, HPA071347" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Actin filaments" "CAB033265: AB_2201163, CAB037325: , HPA034631: AB_10669994, HPA071347: AB_2732179" "unprognostic (2.09e-2)" "unprognostic (7.72e-3)" "unprognostic (3.95e-2)" "unprognostic (2.78e-3)" "unprognostic (3.07e-2)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.53e-6)" "unprognostic (1.23e-1)" "unprognostic (5.72e-2)" "unprognostic (2.21e-2)" "unprognostic (6.35e-2)" 91.8 112.1 103.5 21.3 60.7 0.3 48.6 0.0 88.9 23.2 0.8 37.4 31.4 38.7 20.9 31.0 30.8 32.2 369.6 91.2 5.2 60.6 38.5 72.1 10.6 18.2 8.5 34.6 32.9 17.1 21.6 23.8 5.2 46.0 17.5 10.0 21.6 29.1 1296.3 15.4 39.6 38.9 20.6 38.9 34.9 17.0 5.1 6.6 31.1 502.1 11.1 56.8 22.3 34.9 0.5 24.2 0.2 0.3 3.5 3.2 88.4 13.8 18.9 4.6 3.7 21.6 9.7 0.1 72.8 19.9 29.2 8.9 0.1 13.5 1.9 0.2 0.2 0.0 37.4 4.7 19.6 0.0 0.9 3.7 21.3 5.2 3.7 27.5 72.7 0.2 0.2 0.2 4.4 1.6 0.1 0.7 2.8 9.3 11.6 0.5 0.7 0.2 3.4 1.9 8.5 39.3 19.9 21.6 0.7 31.1 1.6 6.6 178.0 17.4 53.2 0.4 3.6 0.8 0.2 1.3 152.5 0.3 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.5 60.7 0.0 88.9 91.2 5.2 18.2 8.5 5.2 20.6 5.1 34.9 51.1 35.3 12.2 1.3 4.8 4.6 3.0 32.6 1.8 1.9 6.4 2.5 264.7 27.1 17.0 7.3 2.1 14.8 0.5 70.5 0.0 43.7 1.7 0.4 0.4 56.3 13.8 2.7 22.5 34.5 6.0 19.9 4.6 0.5 0.0 40.9 62.8 40.0 2.1 0.0 5.7 8.4 2.0 10.8 5.1 3.4 2.8 0.9 5.4 6.5 24.0 7.2 0.0 2.5 1.3 35.6 24.4 27.8 0.6 5.7 52.6 4.4 7.6 0.8 46.0 18.0 29.2 1.2 0.8 1.4 2.3 25.9 1.6 8.6 11.8 3.6 SYNPO2L FLJ12921 ENSG00000166317 "Synaptopodin 2 like" Q9H987 10 73644881-73663803 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "heart muscle: 262.3;skeletal muscle: 279.2;tongue: 87.2" "Cell type enriched" "Detected in some" 52 "Cardiomyocytes: 665.1" "Group enriched" "Detected in some" 6 "breast cancer: 1.5;head and neck cancer: 1.4;prostate cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 4.1;HSkMC: 3.2;RH-30: 3.0;SK-BR-3: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055192, HPA057142" Enhanced Supported "Nuclear speckles,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "Cell Junctions, Cytosol" "HPA055192: AB_2682732, HPA057142: AB_2683348" "unprognostic (2.75e-1)" "unprognostic (1.58e-1)" "unprognostic (1.20e-3)" "unprognostic (3.65e-3)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (4.54e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-2)" "unprognostic (4.50e-2)" "unprognostic (2.32e-1)" "unprognostic (7.44e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.72e-2)" "unprognostic (1.34e-1)" 0.1 0.5 0.7 0.1 0.7 0.3 3.6 0.8 0.9 0.4 0.1 0.0 0.1 0.1 0.1 11.8 0.1 0.1 262.3 0.7 0.5 0.1 0.1 1.2 0.2 0.7 0.6 0.2 0.4 0.0 0.1 0.6 0.5 3.1 0.0 0.4 4.8 0.0 279.2 0.3 0.0 0.0 0.5 0.2 0.1 0.3 0.6 0.1 0.2 87.2 0.2 0.0 1.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.5 0.6 0.1 0.0 4.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.3 0.1 0.0 3.2 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.1 0.1 0.1 0.0 3.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.7 0.7 0.8 0.9 0.7 0.5 0.7 0.6 0.5 0.5 0.6 0.7 0.5 3.2 0.0 0.3 0.9 1.5 1.4 0.0 2.2 1.9 1.0 0.8 665.1 0.0 0.7 0.0 2.1 0.2 0.5 0.0 0.0 0.0 2.6 0.1 0.4 5.0 0.0 0.0 0.3 0.0 0.2 12.6 0.0 0.3 1.3 0.3 0.0 0.4 0.2 0.0 0.9 0.0 0.0 0.6 2.1 1.1 0.9 0.8 1.8 1.0 0.3 0.4 0.0 1.5 1.1 0.0 0.0 0.4 0.3 0.9 0.0 0.2 0.7 1.2 0.0 12.0 5.2 0.8 1.3 0.4 0.4 0.0 0.7 0.2 0.0 1.0 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYT2 ENSG00000143858 "Synaptotagmin 2" Q8N9I0 1 202590596-202710454 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Differentiation "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 73.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 23.2;Inhibitory neurons: 22.7;Oligodendrocytes: 7.4" "Cancer enriched" "Detected in some" 7 "testis cancer: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 8.5;NTERA-2: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063655 Enhanced Supported NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA063655: AB_2685077" "unprognostic (1.32e-2)" "unprognostic (4.99e-2)" "unprognostic (4.89e-2)" "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (2.24e-2)" "unprognostic (3.00e-1)" "unprognostic (2.35e-3)" "unprognostic (8.81e-3)" "unprognostic (1.17e-1)" "unprognostic (1.53e-2)" "unprognostic (6.33e-2)" "unprognostic (1.56e-2)" "unprognostic (6.23e-2)" "unprognostic (3.26e-1)" "unprognostic (2.54e-1)" "unprognostic (5.17e-3)" 0.2 1.3 2.6 0.2 8.8 0.0 0.1 46.3 73.4 0.2 0.3 0.3 0.2 0.4 0.8 0.0 0.2 0.2 0.3 0.5 16.8 0.0 0.0 0.0 0.1 66.0 17.5 0.6 0.0 0.0 0.0 0.0 68.3 0.1 0.1 5.2 0.2 0.0 0.2 0.1 0.2 0.0 13.9 0.2 0.1 0.5 23.1 0.0 0.0 0.0 0.0 0.2 0.1 20.7 0.0 0.1 8.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 8.8 46.3 73.4 0.5 16.8 66.0 17.5 68.3 13.9 23.1 20.7 0.2 0.0 0.0 2.6 0.1 0.5 1.6 1.1 0.0 3.6 0.2 0.1 2.9 0.0 0.5 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.2 0.6 1.7 0.3 0.0 0.0 23.2 0.0 0.1 0.3 0.0 2.0 0.0 0.9 0.0 0.0 0.0 3.3 22.7 0.1 0.0 0.0 0.0 0.5 3.4 0.2 0.0 1.0 0.1 1.2 0.0 1.0 7.4 0.0 0.0 1.9 0.0 0.4 0.0 0.1 0.7 5.1 0.0 0.3 0.6 0.3 0.9 0.0 0.6 0.1 0.1 0.1 0.4 2.2 SYT7 "IPCA-7, MGC150517, PCANAP7, SYT-VII" ENSG00000011347 "Synaptotagmin 7" O43581 11 61513714-61581148 "Predicted intracellular proteins, Predicted membrane proteins" Exocytosis Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;liver: 86.7;salivary gland: 57.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.2;Enteroendocrine cells: 49.8;Excitatory neurons: 82.1;Hepatocytes: 70.7;Prostatic glandular cells: 36.8;Syncytiotrophoblasts: 66.4" "Cancer enhanced" "Detected in all" "prostate cancer: 54.4" "Region enhanced" "Detected in many" "cerebral cortex: 78.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 35.0;hTERT-HME1: 89.5;RT4: 37.8;SCLC-21H: 28.4;SK-BR-3: 40.7;T-47d: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012869 Enhanced NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA012869: AB_1857698" "unprognostic (7.09e-2)" "unprognostic (8.26e-2)" "unprognostic (2.43e-1)" "unprognostic (2.10e-2)" "unprognostic (5.42e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (4.37e-2)" "unprognostic (5.08e-2)" "unprognostic (2.74e-3)" "unprognostic (1.79e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (2.23e-3)" "unprognostic (2.47e-1)" 3.8 4.3 17.7 1.2 33.8 0.1 9.2 0.0 78.4 3.1 0.0 5.0 2.3 2.6 1.8 3.5 3.4 1.2 19.0 30.7 1.9 24.7 86.7 1.9 0.3 0.0 1.9 1.3 16.7 5.7 51.6 18.4 0.0 50.8 5.3 8.0 57.0 0.9 3.6 4.2 5.2 1.8 0.0 2.1 3.7 4.0 13.9 0.4 8.0 1.8 0.3 1.9 3.3 38.5 13.4 1.9 0.5 0.2 1.0 14.1 10.4 0.2 35.0 0.6 0.5 3.5 6.9 0.0 0.6 0.2 1.3 6.9 0.9 0.2 0.2 0.2 1.7 0.0 1.7 2.1 0.9 0.1 0.1 0.4 7.8 4.2 89.5 0.2 0.2 0.8 0.1 0.2 0.5 21.6 0.1 0.3 2.4 24.8 14.1 0.0 0.7 1.7 0.0 37.8 28.4 5.2 1.9 40.7 0.3 5.6 39.8 0.0 0.0 8.6 3.1 10.1 0.2 0.0 0.0 0.1 0.9 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 33.8 0.0 78.4 30.7 1.9 0.0 1.9 0.0 0.0 13.9 38.5 10.6 0.0 0.5 4.2 0.2 0.3 0.4 5.1 0.0 22.6 23.2 16.3 22.3 1.5 5.0 5.5 0.0 45.2 0.6 1.9 5.9 1.2 8.4 0.3 4.3 4.9 49.8 2.7 82.1 1.6 3.4 3.0 0.0 0.5 0.0 5.9 4.6 70.7 4.0 21.9 17.8 30.2 6.1 1.0 0.0 7.6 3.4 0.1 1.8 7.5 0.0 0.6 0.0 6.0 2.5 1.0 4.6 2.2 0.0 36.8 3.5 0.1 1.3 3.5 0.0 2.8 1.4 0.8 3.9 0.9 0.1 66.4 0.2 0.6 2.4 1.7 TACC2 "AZU-1, ECTACC" ENSG00000138162 "Transforming acidic coiled-coil containing protein 2" O95359 10 121989163-122254545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 251.7;skeletal muscle: 387.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.1;Syncytiotrophoblasts: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031020, HPA031021, HPA061394" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 32000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA031020: AB_10669988, HPA031021: AB_2673701, HPA061394: AB_2684500" "unprognostic (3.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-2)" "unprognostic (7.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (9.15e-2)" "unprognostic (8.43e-3)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (2.13e-1)" "unprognostic (1.83e-2)" "prognostic favorable (2.50e-10)" "unprognostic (7.02e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (1.61e-1)" 22.1 15.3 18.2 5.3 18.6 0.2 20.9 23.6 22.7 32.3 28.6 91.5 15.3 26.1 9.2 64.2 32.9 12.9 251.7 19.1 18.8 33.9 18.8 68.7 1.0 16.0 16.9 8.8 25.3 36.4 58.7 21.6 14.8 67.7 20.7 7.2 60.7 13.5 387.1 103.3 35.7 22.0 11.8 4.2 49.1 5.8 16.9 5.7 50.7 159.0 5.7 62.4 49.1 17.7 17.8 55.1 26.5 15.2 7.4 7.4 31.7 7.7 20.7 10.5 7.3 22.7 28.9 0.0 7.0 12.3 12.1 58.1 8.5 20.9 10.9 3.0 4.4 0.0 7.7 43.8 11.5 0.0 0.3 3.4 86.0 5.6 36.6 8.6 22.2 0.1 4.5 0.6 10.4 23.5 0.2 9.9 15.7 27.6 24.8 0.3 15.2 8.5 28.9 26.9 17.6 14.2 12.7 52.0 29.5 7.6 10.2 0.4 20.6 4.7 3.5 11.8 14.5 2.4 11.7 0.3 8.7 0.1 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 18.6 23.6 22.7 19.1 18.8 16.0 16.9 14.8 11.8 16.9 17.7 15.5 83.3 94.1 16.3 0.7 33.6 49.7 54.3 33.0 21.6 23.4 14.1 210.1 8.6 70.7 36.8 0.0 53.3 0.4 75.2 1.9 8.2 2.4 88.4 11.0 21.3 30.0 0.0 32.8 14.2 4.4 21.2 38.7 62.8 7.0 0.1 6.1 18.9 6.5 43.7 48.2 38.8 57.0 0.3 4.3 2.6 6.8 1.9 7.2 7.5 0.1 1.1 0.0 80.9 7.6 19.4 47.1 7.5 0.2 49.6 36.5 13.5 84.9 2.7 13.1 27.2 23.7 0.5 8.2 79.5 54.0 228.5 2.6 2.8 41.9 80.5 TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 87.9;Proximal enterocytes: 81.2;Proximal tubular cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" 12.8 18.6 16.6 8.2 17.4 8.3 10.9 18.9 18.4 8.8 17.7 17.8 18.9 11.1 9.7 13.4 9.3 5.5 42.3 16.5 17.5 30.1 69.2 7.7 10.4 17.4 17.4 8.3 12.0 18.2 9.5 8.3 17.3 9.5 16.1 9.4 11.4 9.2 61.5 11.3 16.7 9.7 16.9 11.5 15.1 12.1 17.6 9.9 9.4 55.9 12.2 11.8 9.2 16.7 39.6 61.2 19.4 20.2 16.5 23.5 25.7 28.5 26.8 56.2 44.4 40.5 23.2 32.6 21.2 33.1 38.9 35.8 43.0 41.5 52.6 17.3 58.1 32.0 29.8 72.3 45.5 38.3 21.7 29.0 28.6 48.5 51.1 20.9 29.6 24.2 44.4 24.1 26.6 71.6 44.7 28.7 16.8 42.5 62.9 28.1 47.7 40.8 33.2 27.6 29.5 32.4 19.6 64.0 55.3 25.3 53.3 29.1 26.4 39.9 29.9 27.5 50.7 25.9 27.2 38.7 30.4 26.0 29.6 2.2 9.4 9.0 9.8 8.5 10.7 7.5 13.7 9.7 10.6 9.9 12.4 10.3 1.4 17.8 7.4 7.0 10.2 9.4 16.6 17.4 18.9 18.4 16.5 17.5 17.4 17.4 17.3 16.9 17.6 16.7 9.8 3.2 6.3 2.6 12.0 2.5 8.0 21.1 8.6 8.2 7.8 10.9 54.0 17.2 11.5 14.7 2.1 32.1 8.2 32.9 54.8 29.1 15.3 8.0 11.4 14.2 13.8 17.4 4.0 27.4 28.9 14.1 16.8 6.4 9.5 16.2 8.6 87.9 26.3 6.7 3.9 21.7 12.2 10.7 3.9 46.0 11.8 9.2 10.6 2.8 22.0 15.5 14.4 1.5 3.2 30.0 25.8 11.3 10.7 11.6 81.2 109.7 9.1 13.4 19.7 10.7 14.6 26.8 13.9 18.6 4.3 19.8 10.1 40.7 32.8 7.1 TANGO2 "C22orf25, DKFZp761P1121" ENSG00000183597 "Transport and golgi organization 2 homolog" Q6ICL3 22 20017014-20067164 "Disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 78.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003080 Approved NA NA 200000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA003080: AB_1078350" "unprognostic (4.05e-1)" "unprognostic (1.90e-3)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (3.48e-1)" "unprognostic (1.37e-1)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (6.13e-2)" "unprognostic (6.76e-2)" "prognostic favorable (3.01e-4)" "unprognostic (2.21e-1)" "unprognostic (1.83e-3)" "unprognostic (3.95e-2)" "unprognostic (5.49e-2)" "unprognostic (2.60e-1)" "unprognostic (2.62e-2)" 17.0 26.7 20.9 13.8 19.2 50.5 13.4 19.1 23.8 10.9 15.9 14.9 9.8 13.0 9.2 11.5 10.9 10.9 78.9 21.8 22.4 21.3 20.0 19.2 17.7 24.7 26.6 7.9 15.4 27.7 19.7 11.6 30.2 17.1 11.3 6.4 12.2 12.2 27.7 12.8 16.2 12.0 20.6 34.0 21.2 7.5 25.7 12.4 24.3 29.0 11.7 15.1 9.7 20.5 15.6 14.2 4.8 9.6 33.6 10.9 8.7 15.7 20.8 14.5 12.8 10.0 12.1 6.2 11.1 42.4 20.2 18.9 11.2 17.5 9.2 36.8 11.4 16.9 11.9 12.0 24.6 15.7 29.1 15.6 12.9 21.0 11.6 14.5 21.6 10.4 44.0 13.1 20.8 17.7 10.3 10.7 2.3 37.7 9.5 9.5 12.9 4.0 11.7 19.9 8.4 4.7 16.1 27.7 35.3 10.3 7.0 14.3 14.7 19.0 14.4 25.2 11.0 6.7 4.1 6.4 25.9 12.9 13.6 76.3 44.1 77.8 14.9 53.4 16.2 20.5 15.9 19.2 41.6 15.7 10.0 13.1 55.8 31.3 70.1 14.3 28.7 39.6 20.9 19.2 19.1 23.8 21.8 22.4 24.7 26.6 30.2 20.6 25.7 20.5 5.8 16.0 5.8 10.7 11.9 3.8 3.9 4.2 2.2 4.9 3.9 3.4 17.1 10.0 4.6 7.3 4.2 10.6 10.2 11.5 19.6 11.5 5.5 2.7 3.4 5.7 6.6 111.4 20.6 9.7 17.4 5.9 9.2 4.9 15.2 4.5 6.4 6.4 39.4 10.1 13.3 7.0 8.2 21.6 7.1 15.9 5.0 24.0 19.6 15.9 24.8 7.6 19.6 3.0 30.9 11.6 9.2 4.9 7.2 4.8 13.8 7.7 6.1 2.9 19.7 3.0 6.6 4.8 3.1 5.3 4.5 11.5 9.7 13.0 6.3 3.5 TARS2 "FLJ12528, TARSL1" ENSG00000143374 "Threonyl-tRNA synthetase 2, mitochondrial" Q9BW92 1 150487364-150507609 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028626 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "HPA028626: AB_10601719" "unprognostic (2.48e-1)" "unprognostic (7.75e-2)" "unprognostic (6.68e-2)" "unprognostic (3.75e-3)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "unprognostic (4.93e-2)" "unprognostic (2.14e-1)" "unprognostic (9.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.25e-1)" "unprognostic (3.76e-2)" "unprognostic (9.23e-2)" "unprognostic (9.29e-3)" "unprognostic (4.19e-2)" "unprognostic (1.14e-2)" "unprognostic (5.55e-2)" 9.8 16.5 11.8 10.6 11.4 10.0 10.3 11.2 12.5 9.5 10.9 10.3 8.9 8.9 13.0 13.4 11.7 7.7 20.3 11.3 11.5 14.3 25.3 8.6 14.7 12.0 11.5 11.7 8.4 17.7 9.3 8.9 12.7 8.7 11.3 14.7 9.7 9.3 31.9 11.8 9.6 10.0 10.4 12.5 12.0 11.0 11.9 12.6 11.2 31.1 15.4 9.6 9.4 12.8 33.5 27.4 18.1 27.4 19.9 18.2 34.1 15.9 17.2 30.7 30.8 22.4 30.3 48.0 34.2 12.0 21.1 33.8 44.2 36.8 23.5 29.2 38.4 22.7 25.2 22.7 19.7 31.4 33.4 16.2 30.2 23.4 31.6 19.9 20.1 26.4 40.3 32.6 21.8 40.4 27.0 26.0 22.3 46.0 40.2 27.5 23.0 59.8 20.9 15.7 25.5 29.8 24.1 52.5 38.7 25.4 42.3 48.9 11.9 17.8 18.8 14.9 27.2 31.2 39.6 36.2 26.6 36.3 17.6 30.5 15.4 30.5 21.0 27.0 21.3 28.7 20.5 21.2 25.0 25.3 19.6 20.7 2.4 33.2 29.3 16.7 31.4 18.3 11.8 11.4 11.2 12.5 11.3 11.5 12.0 11.5 12.7 10.4 11.9 12.8 6.3 3.2 12.8 6.2 13.2 3.3 5.6 10.4 5.2 15.3 6.2 4.6 22.3 11.5 11.9 7.3 20.9 24.5 8.8 8.2 11.7 11.5 1.6 9.6 12.8 7.4 4.2 11.1 9.3 9.8 14.3 8.4 13.3 11.7 22.2 11.0 6.8 22.6 13.2 15.2 9.1 12.6 6.1 7.7 5.2 2.5 8.4 8.8 3.6 2.8 12.5 7.6 9.2 6.0 9.9 11.9 3.5 7.2 9.9 4.5 8.5 8.8 9.4 16.8 6.6 10.3 8.3 18.2 12.3 7.4 4.0 14.1 10.6 15.8 12.6 4.8 TBC1D7 "dJ257A7.3, FLJ32666" ENSG00000145979 "TBC1 domain family member 7" Q9P0N9 6 13266542-13328583 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "melanoma: 13.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 320.4;U-266/84: 174.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034748 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "HPA034748: AB_10671232" "unprognostic (9.53e-2)" "unprognostic (8.39e-2)" "unprognostic (3.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (3.95e-3)" "unprognostic (5.54e-2)" "unprognostic (9.30e-2)" "prognostic favorable (4.98e-5)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.57e-1)" "unprognostic (3.46e-2)" "unprognostic (3.48e-1)" "unprognostic (2.78e-2)" 9.4 12.0 14.3 9.7 15.9 26.5 11.5 13.0 26.3 10.8 9.9 15.2 14.5 8.4 20.0 17.1 6.6 10.3 31.7 14.3 12.9 21.4 17.5 11.0 13.9 11.8 11.6 7.7 10.2 12.4 10.7 14.4 13.4 12.4 16.5 11.5 12.2 7.0 16.2 13.8 10.8 10.1 10.7 12.3 9.8 14.0 12.7 16.9 8.0 14.5 15.6 10.0 11.4 15.8 26.2 25.5 36.0 36.8 27.5 15.7 24.9 11.5 13.3 24.0 26.8 51.8 23.0 18.1 75.0 19.3 55.8 20.8 24.5 29.0 21.9 28.4 29.1 50.3 16.5 45.8 63.6 32.7 73.6 21.4 40.6 29.7 19.3 24.0 40.5 57.2 57.3 23.7 30.8 42.8 42.2 78.5 24.4 32.4 24.6 61.7 15.7 77.7 54.1 35.1 69.4 30.8 28.4 55.4 320.4 71.3 53.6 19.1 29.4 24.6 30.8 13.6 16.2 55.8 174.2 86.2 23.1 34.1 51.1 28.2 21.6 27.0 11.6 20.0 7.6 15.4 9.9 10.5 43.3 14.5 9.1 11.1 42.2 21.4 13.7 42.2 14.6 10.4 14.3 15.9 13.0 26.3 14.3 12.9 11.8 11.6 13.4 10.7 12.7 15.8 11.0 12.8 13.9 3.9 16.2 7.5 9.9 37.2 11.4 6.5 15.7 20.6 30.6 15.7 28.8 16.5 4.2 41.0 15.0 12.9 33.2 16.4 8.1 15.2 12.7 12.4 9.0 57.4 8.4 14.3 23.3 9.9 15.8 15.7 9.5 14.4 12.1 15.2 24.2 10.1 9.5 18.3 50.8 12.9 23.0 5.8 4.4 31.3 10.6 4.7 13.9 8.9 13.4 6.6 7.3 22.2 18.3 5.3 21.9 11.6 13.1 56.1 16.4 8.0 13.1 5.6 20.2 14.7 34.3 21.7 8.9 46.9 11.3 14.4 16.4 13.4 TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.1;lung: 20.8;placenta: 28.7" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 104.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 18.9;BJ hTERT+: 41.5;BJ hTERT+ SV40 Large T+: 9.2;BJ hTERT+ SV40 Large T+ RasG12V: 12.2;HAP1: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" 3.4 0.0 0.1 0.0 0.0 0.0 4.4 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 88.1 0.9 0.0 0.0 0.0 20.8 0.6 0.3 0.1 0.0 0.0 1.3 0.0 28.7 0.3 3.4 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 5.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 18.9 41.5 9.2 12.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 16.3 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.9 0.0 0.3 0.1 0.3 0.0 0.0 0.2 2.9 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.0 4.5 0.1 0.1 104.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 7.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 TCEA3 TFIIS.H ENSG00000204219 "Transcription elongation factor A3" O75764 1 23380909-23424748 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 513.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 214.8;Hepatocytes: 205.9;Intestinal goblet cells: 376.2;Proximal tubular cells: 260.9;Undifferentiated cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 8.4;naive CD4 T-cell: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 13.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 15.3;Hep G2: 55.1;OE19: 28.7;SiHa: 18.2;T-47d: 28.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044960, HPA055811" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA044960: AB_10964053, HPA055811: AB_2682932" "unprognostic (1.58e-1)" "unprognostic (1.75e-3)" "unprognostic (9.18e-2)" "unprognostic (3.82e-2)" "unprognostic (2.77e-3)" "prognostic favorable (2.56e-4)" "unprognostic (2.86e-2)" "unprognostic (4.70e-3)" "unprognostic (7.37e-3)" "unprognostic (2.85e-1)" "unprognostic (2.22e-2)" "unprognostic (3.27e-1)" "unprognostic (2.23e-1)" "unprognostic (4.01e-1)" "unprognostic (5.20e-2)" "unprognostic (3.15e-1)" "unprognostic (5.58e-2)" 17.5 95.6 4.7 4.6 4.3 0.6 19.6 4.1 4.7 35.7 7.8 87.1 15.8 17.0 7.3 40.5 28.3 11.6 71.6 4.0 4.4 64.9 160.7 20.4 2.4 6.0 4.9 81.9 229.4 16.3 14.9 3.9 5.4 59.9 39.8 3.2 100.3 14.5 513.3 53.4 35.2 9.2 5.2 10.6 75.9 4.7 4.1 1.8 41.2 173.1 4.5 36.2 38.7 5.1 0.0 0.1 0.5 0.5 2.5 15.3 9.0 6.4 4.1 3.2 1.9 4.1 0.5 0.2 0.7 7.9 1.0 9.1 0.5 0.1 2.8 0.0 0.1 0.0 6.9 55.1 1.9 0.8 0.0 10.1 2.8 2.9 0.0 7.1 0.4 0.1 0.0 0.0 1.1 1.5 0.4 6.1 0.0 28.7 1.8 0.1 0.0 0.2 0.0 0.1 0.5 0.1 18.2 0.8 0.8 1.5 28.4 2.8 0.4 0.0 0.2 0.7 0.0 0.5 5.3 0.0 0.5 0.5 0.6 0.0 0.2 0.0 0.4 0.7 0.4 0.0 8.4 1.1 2.9 0.0 13.6 6.1 0.0 0.2 0.2 0.9 0.8 2.3 4.7 4.3 4.1 4.7 4.0 4.4 6.0 4.9 5.4 5.2 4.1 5.1 10.5 125.0 109.5 4.2 1.9 27.4 53.4 30.9 30.7 2.3 46.3 42.4 109.8 100.1 57.2 42.3 2.1 3.3 1.9 158.0 199.6 37.7 6.1 7.7 6.6 13.4 55.9 5.7 2.8 97.9 33.9 45.2 69.3 20.8 9.5 214.8 8.2 205.9 1.5 25.2 4.5 376.2 6.1 7.6 65.4 17.9 17.1 8.4 24.9 3.7 3.2 6.8 3.1 2.0 1.3 25.5 143.0 15.4 0.5 38.8 154.3 260.9 29.4 1.4 19.7 90.1 24.0 0.7 2.6 61.1 54.8 2.2 8.4 52.0 223.5 73.9 TCF24 bHLHa25 ENSG00000261787 "Transcription factor 24" Q7RTU0 8 66946501-66962591 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.0;kidney: 1.1;testis: 1.5" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 5.1;Spermatocytes: 4.7;Spermatogonia: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.2;HEK 293: 5.5;HMC-1: 4.7;K-562: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (1.07e-1)" "unprognostic (9.14e-3)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (8.30e-2)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (2.25e-1)" "unprognostic (9.38e-3)" "unprognostic (9.36e-2)" "unprognostic (1.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-1)" 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 1.0 0.3 0.1 1.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.0 0.0 5.5 0.2 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.1 0.7 0.7 0.6 0.5 0.3 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TECRL "DKFZp313B2333, DKFZp313D0829, GPSN2L, SRD5A2L2, TERL" ENSG00000205678 "Trans-2,3-enoyl-CoA reductase like" Q5HYJ1 4 64275257-64409468 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "heart muscle: 554.3" "Cell type enriched" "Detected in some" 35 "Cardiomyocytes: 1775.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" 0.0 0.3 0.1 0.1 0.3 1.0 0.6 0.8 0.3 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.1 554.3 0.1 0.5 0.0 0.0 0.2 0.4 0.3 0.1 0.1 0.5 0.1 0.0 0.1 0.4 1.7 0.0 0.5 0.3 0.0 56.2 1.0 0.0 0.0 0.0 0.1 0.1 0.1 0.5 0.0 0.6 1.9 0.0 0.3 0.0 0.9 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.3 0.1 0.5 0.3 0.1 0.4 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1775.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.2 0.0 0.0 50.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.6 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TESC "CHP3, FLJ20607, TSC" ENSG00000088992 Tescalcin Q96BS2 12 117038923-117099479 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 329.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 183.0;Erythroid cells: 222.9;Exocrine glandular cells: 481.2;Gastric mucus-secreting cells: 316.0;Late spermatids: 319.3;Pancreatic endocrine cells: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 261.1" "Lineage enriched" "Detected in all" 5 "monocytes: 261.1" "Cell line enhanced" "Detected in many" "HMC-1: 398.5;NB-4: 675.1;OE19: 288.1;U-937: 221.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053200 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm Cytosol "HPA053200: AB_2682079" "unprognostic (4.53e-3)" "unprognostic (5.98e-2)" "unprognostic (6.50e-2)" "unprognostic (2.23e-3)" "unprognostic (6.31e-2)" "unprognostic (2.05e-3)" "unprognostic (4.98e-3)" "unprognostic (3.35e-1)" "unprognostic (4.35e-1)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-2)" "unprognostic (8.65e-2)" "unprognostic (2.57e-1)" "unprognostic (1.56e-2)" "unprognostic (5.67e-3)" 8.1 46.5 17.4 10.3 36.8 118.8 8.9 16.4 25.4 4.3 15.7 3.8 7.2 3.9 121.9 3.3 4.0 36.1 71.5 26.5 15.0 26.5 4.9 10.2 8.0 17.8 15.0 5.3 102.4 9.4 26.7 10.2 18.2 9.8 2.8 0.5 329.9 19.7 5.1 9.7 7.3 2.8 14.8 11.9 138.4 31.1 15.5 7.4 10.7 8.1 10.3 29.3 5.3 18.9 0.2 97.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 4.3 13.8 4.7 0.0 0.2 0.6 8.1 0.0 0.0 37.5 19.2 115.5 9.8 78.1 0.0 49.2 398.5 0.1 0.0 0.0 0.0 0.0 0.0 18.5 54.0 0.9 0.0 2.2 95.5 675.1 9.0 288.1 0.0 0.4 0.0 52.4 56.5 15.0 17.0 6.1 0.1 0.1 3.6 0.9 0.0 53.9 0.0 0.0 1.7 0.2 0.4 17.0 38.2 0.0 0.1 221.8 0.5 0.0 51.0 51.5 7.0 67.9 0.4 5.5 2.4 9.1 35.8 13.1 0.3 3.8 12.6 11.6 261.1 2.6 3.5 19.0 17.4 36.8 16.4 25.4 26.5 15.0 17.8 15.0 18.2 14.8 15.5 18.9 35.6 0.0 0.0 5.9 16.2 2.7 0.3 0.4 1.8 0.8 5.5 67.1 58.3 183.0 0.9 12.9 0.0 0.4 21.1 0.2 74.3 159.5 106.5 1.3 0.7 43.6 1.8 222.9 26.1 481.2 0.6 7.9 316.0 3.2 71.1 1.2 1.8 0.5 48.0 0.0 2.0 1.5 0.0 17.9 6.1 319.3 3.1 30.6 72.9 8.4 41.0 0.2 25.7 2.5 1.5 215.6 0.9 3.4 25.8 3.5 0.2 6.1 0.0 1.5 144.7 1.9 68.4 63.0 20.3 0.5 2.0 1.2 28.3 66.7 2.3 1.3 THEM6 "C8orf55, DSCD75" ENSG00000130193 "Thioesterase superfamily member 6" Q8WUY1 8 142727223-142736927 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 82.4;RT4: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023255 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted - unknown location" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "HPA023255: AB_1845782" "unprognostic (6.20e-3)" "unprognostic (2.21e-1)" "unprognostic (9.10e-2)" "unprognostic (5.33e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-2)" "unprognostic (1.74e-2)" "unprognostic (6.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.44e-1)" "unprognostic (4.91e-2)" "unprognostic (6.76e-2)" "prognostic favorable (6.66e-7)" "unprognostic (7.02e-3)" "unprognostic (3.55e-2)" "unprognostic (2.39e-2)" "prognostic favorable (4.49e-4)" 14.3 17.2 15.8 4.4 13.9 5.3 15.6 14.4 18.3 9.6 12.0 13.3 11.5 6.9 3.5 21.0 9.4 7.3 16.6 16.1 15.4 21.6 47.0 10.6 6.5 20.7 17.2 4.4 23.1 15.7 12.5 8.3 16.7 12.5 5.1 1.4 16.3 10.3 12.4 16.6 11.6 3.5 15.0 11.0 15.6 3.7 15.9 6.8 14.2 7.2 4.1 17.2 11.5 14.2 28.5 23.1 3.5 23.9 10.9 3.8 16.6 14.3 11.8 21.5 14.9 14.2 41.5 11.9 31.8 5.4 8.0 64.4 10.2 31.0 3.5 9.9 28.2 9.1 12.3 28.9 11.9 5.3 9.2 5.5 10.9 4.2 6.0 4.3 18.4 16.6 4.3 5.9 3.7 82.4 21.7 1.3 5.4 53.0 74.5 24.9 2.4 27.4 25.9 114.0 53.1 20.8 21.9 64.7 18.6 3.2 31.9 4.3 10.7 9.2 6.7 26.8 2.5 3.8 5.6 5.2 9.5 25.7 11.6 7.2 4.9 2.6 10.9 9.2 16.6 5.1 11.6 14.1 4.7 6.7 13.6 12.9 0.7 11.1 9.0 3.6 11.6 9.1 15.8 13.9 14.4 18.3 16.1 15.4 20.7 17.2 16.7 15.0 15.9 14.2 35.4 9.6 5.8 6.2 6.7 3.6 7.5 5.7 2.8 10.4 24.7 25.3 7.4 11.5 7.8 18.4 6.2 18.3 11.5 16.6 5.9 13.7 3.3 5.5 3.0 14.6 31.8 11.6 11.3 11.6 10.1 4.8 7.7 9.0 0.0 6.6 19.2 20.8 11.4 16.8 7.8 13.5 6.1 3.1 1.4 15.7 2.8 3.9 5.4 2.8 2.3 13.5 16.5 11.6 7.3 9.4 9.0 4.1 3.7 10.7 29.0 16.2 2.4 11.3 0.0 6.1 4.3 2.7 5.7 18.4 7.7 3.4 10.3 8.2 22.4 25.1 THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 103.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 106.4;Basal squamous epithelial cells: 449.0;Microglial cells: 247.3;Squamous epithelial cells: 141.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 45.3;BJ hTERT+: 53.0;T-47d: 43.3;TIME: 66.6;U-2197: 44.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.0" "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" 4.8 8.4 9.8 1.6 7.8 0.0 14.7 6.1 8.6 103.7 9.5 7.0 7.9 22.2 7.8 60.3 37.0 10.9 41.6 8.5 7.2 14.2 7.0 10.3 0.9 7.8 9.1 3.1 6.4 0.7 9.7 3.6 7.6 34.0 6.9 1.2 11.4 15.0 3.0 8.5 8.7 10.3 7.0 1.9 12.0 3.1 15.9 1.6 8.8 2.5 2.5 13.3 38.5 5.9 6.0 45.3 0.8 13.0 6.7 40.2 0.2 22.0 53.0 11.2 5.8 0.3 8.7 0.0 17.7 7.8 38.5 17.0 1.8 9.1 6.8 2.0 2.0 0.0 4.4 0.0 4.3 0.0 0.0 3.0 6.7 6.7 26.6 30.5 20.7 0.0 0.0 0.5 9.2 9.1 0.0 0.1 3.9 0.1 7.8 0.0 0.7 0.8 29.5 6.0 0.7 5.5 8.8 10.9 0.0 5.0 43.3 0.1 66.6 0.2 1.0 44.4 11.8 0.0 0.3 0.0 10.4 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 7.8 6.1 8.6 8.5 7.2 7.8 9.1 7.6 7.0 15.9 5.9 1.1 19.2 9.0 6.5 0.0 13.9 106.4 11.3 449.0 3.0 48.7 43.9 60.1 58.6 7.5 5.5 6.2 0.4 0.8 16.2 1.9 18.3 7.5 19.3 13.2 9.8 3.0 0.0 17.1 1.8 0.4 12.5 2.6 31.8 0.0 0.3 6.1 12.3 0.2 0.0 19.1 6.1 0.0 0.0 2.1 16.9 17.4 1.6 8.8 247.3 0.0 0.3 0.0 8.5 6.7 13.6 11.0 74.4 1.2 94.6 29.3 0.5 11.0 0.9 0.0 16.8 6.6 0.9 1.7 141.5 10.9 0.8 3.1 42.2 13.2 29.7 TIGD3 ENSG00000173825 "Tigger transposable element derived 3" Q6B0B8 11 65354751-65357613 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5;intestine: 2.5;testis: 5.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 9.6;Spermatocytes: 40.5;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 7.7;eosinophil: 10.9;neutrophil: 17.5" "Lineage enriched" "Detected in many" 11 "granulocytes: 17.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA040016 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA040016: AB_10805600" "unprognostic (1.33e-1)" "unprognostic (1.81e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-3)" "unprognostic (9.04e-4)" "unprognostic (1.48e-4)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "unprognostic (3.94e-3)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (7.55e-3)" "unprognostic (1.01e-1)" "unprognostic (2.11e-1)" "unprognostic (1.75e-3)" 0.1 0.2 1.2 0.2 1.7 0.5 0.1 2.5 2.1 0.1 0.5 0.2 0.8 0.1 0.2 0.2 0.1 0.1 0.4 1.2 1.0 0.3 0.2 0.2 0.4 1.1 1.2 0.3 0.5 0.4 1.2 0.1 1.0 0.2 0.1 0.9 0.3 0.1 0.2 0.1 2.5 0.0 1.1 1.0 0.3 5.0 1.1 1.3 0.1 0.3 0.2 0.1 0.1 1.2 0.8 1.6 1.3 3.5 0.0 0.0 0.5 0.0 0.1 0.3 0.4 1.2 0.2 0.6 0.5 0.1 0.6 0.8 1.3 0.0 0.1 1.1 1.4 0.2 0.9 2.8 0.0 0.5 2.6 0.0 0.1 0.1 0.0 0.0 0.2 1.3 0.9 1.8 0.0 2.1 1.7 1.1 0.7 0.7 0.6 2.5 0.6 2.4 0.0 0.8 3.9 2.4 1.0 1.5 0.6 0.1 2.5 0.8 0.0 0.1 0.6 0.9 0.6 3.7 2.5 0.8 0.0 1.1 0.4 7.7 0.6 10.9 0.0 0.3 0.0 0.4 0.0 0.0 1.0 0.2 0.2 0.0 17.5 0.1 1.5 1.5 0.0 0.2 1.2 1.7 2.5 2.1 1.2 1.0 1.1 1.2 1.0 1.1 1.1 1.2 1.0 0.0 1.1 0.7 4.5 1.5 0.4 0.5 5.7 4.0 1.7 0.9 2.6 0.0 0.3 0.0 0.0 0.4 4.0 0.4 0.0 1.1 4.3 1.0 0.3 0.6 0.0 2.7 0.7 0.6 0.3 0.4 1.1 1.1 0.0 2.9 0.0 0.4 0.3 0.0 1.0 0.6 0.0 0.6 5.7 2.2 0.0 1.3 1.8 1.0 1.9 1.1 0.0 1.0 0.4 0.4 0.1 0.4 3.0 0.8 9.6 0.9 0.6 3.4 0.0 1.2 0.8 40.5 13.5 3.5 1.6 0.8 1.0 0.7 1.1 0.1 TIMM17B "DXS9822, JM3" ENSG00000126768 "Translocase of inner mitochondrial membrane 17B" O60830 X 48893447-48898143 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029093 Approved Approved Microtubules,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Microtubules Mitochondria "HPA029093: AB_10600913" "unprognostic (7.87e-2)" "prognostic favorable (6.63e-4)" "unprognostic (8.44e-2)" "unprognostic (3.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-3)" "unprognostic (1.44e-1)" "unprognostic (2.01e-1)" "unprognostic (1.14e-2)" "unprognostic (2.04e-1)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (9.40e-2)" "unprognostic (5.24e-3)" "unprognostic (8.67e-2)" "prognostic favorable (7.88e-4)" 24.0 42.0 49.8 18.8 51.1 28.2 25.9 50.6 60.6 29.2 47.0 40.3 25.5 27.7 21.0 38.2 29.1 17.6 75.3 50.1 49.6 47.5 48.7 28.1 27.8 49.5 48.9 27.3 33.4 47.6 45.1 23.0 48.9 36.4 19.4 26.2 25.3 27.7 99.1 35.4 32.2 18.0 50.5 37.9 40.5 18.7 50.6 40.7 30.4 83.2 26.8 35.5 28.7 53.1 71.0 127.8 78.7 78.1 24.2 19.3 65.4 31.3 47.7 81.1 52.9 113.3 93.4 51.8 47.4 27.2 131.1 52.5 125.1 68.3 30.4 111.2 140.1 37.6 69.2 101.4 68.3 56.5 35.0 24.9 67.3 60.9 80.8 40.3 37.6 90.1 56.5 118.2 37.8 183.5 89.4 136.7 102.8 93.2 118.3 62.1 51.0 187.8 80.9 41.1 77.6 69.7 48.6 77.0 47.0 98.5 168.7 97.4 26.2 37.1 72.4 89.8 54.9 107.8 137.1 64.3 51.4 100.3 44.6 178.2 123.4 179.9 67.2 123.9 77.4 113.4 67.1 76.3 121.1 113.4 64.8 59.7 139.6 75.7 104.8 127.6 74.4 124.3 49.8 51.1 50.6 60.6 50.1 49.6 49.5 48.9 48.9 50.5 50.6 53.1 23.8 25.6 34.9 4.9 56.5 30.2 52.4 99.0 21.1 40.4 52.9 62.2 40.0 41.5 59.4 73.5 16.7 94.4 45.0 40.2 185.9 94.5 5.6 42.4 25.5 24.6 81.5 48.8 4.3 73.1 94.3 31.0 34.1 37.8 52.0 50.3 24.7 56.0 99.6 35.3 5.6 68.3 91.6 37.6 49.8 7.4 23.9 48.9 44.4 3.7 85.9 48.7 55.6 2.5 9.1 89.9 92.7 23.0 103.7 63.3 102.4 160.0 56.6 43.8 32.9 21.2 45.0 29.0 39.9 52.0 34.4 79.6 48.2 52.7 59.8 61.2 TIMM21 "C18orf55, HSPC154, TIM21" ENSG00000075336 "Translocase of inner mitochondrial membrane 21" Q9BVV7 18 74148523-74160531 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010587, HPA051543" Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA010587: AB_1851244, HPA051543: AB_2681528" "unprognostic (4.88e-1)" "unprognostic (2.20e-2)" "unprognostic (1.16e-1)" "unprognostic (8.61e-2)" "unprognostic (3.81e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (9.22e-5)" "unprognostic (1.42e-1)" "unprognostic (1.59e-2)" "unprognostic (1.93e-2)" "unprognostic (4.79e-3)" "unprognostic (1.55e-3)" "prognostic favorable (1.38e-9)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.66e-2)" 13.8 14.6 22.7 10.1 23.8 8.1 10.6 25.7 29.6 9.7 23.0 16.2 12.2 10.4 11.9 13.3 9.5 5.6 48.7 22.8 23.2 21.0 22.3 7.4 9.9 22.9 22.5 11.9 9.6 18.0 11.4 10.0 23.0 12.2 13.5 14.8 10.2 9.9 50.8 11.1 11.5 9.5 22.6 13.8 12.4 7.0 23.1 7.7 12.4 47.9 10.1 12.6 10.2 24.3 25.6 26.6 24.4 30.2 19.7 17.4 35.9 38.5 12.8 22.8 19.2 19.5 18.3 34.2 12.1 15.0 19.1 41.6 34.0 32.8 38.1 21.7 19.6 14.7 46.2 53.9 10.0 55.6 23.7 16.2 19.4 29.0 19.9 18.6 17.5 19.0 30.2 23.2 27.9 25.6 29.6 45.6 23.5 15.3 48.6 27.5 28.2 42.6 30.2 35.5 25.9 14.2 14.5 35.9 23.8 19.1 24.9 28.6 12.6 53.3 37.9 17.5 40.3 7.3 60.3 37.2 26.0 59.7 38.0 8.7 9.8 6.3 12.7 15.6 15.2 16.0 12.2 10.7 13.2 12.3 15.3 17.6 1.2 17.1 18.2 15.7 10.0 8.8 22.7 23.8 25.7 29.6 22.8 23.2 22.9 22.5 23.0 22.6 23.1 24.3 8.0 12.8 17.8 8.1 12.1 8.0 9.3 30.2 21.6 17.1 9.0 12.6 165.5 14.3 16.7 5.5 6.2 29.4 10.2 9.4 54.8 13.2 3.1 7.3 13.5 13.1 14.4 16.2 8.6 9.4 28.3 19.0 14.8 6.7 9.5 12.6 11.7 20.2 18.8 16.8 11.1 11.5 8.2 11.7 3.5 1.5 11.5 8.5 1.8 6.5 13.4 20.0 9.2 8.5 9.2 9.1 6.2 12.4 25.7 10.5 12.5 34.5 15.0 20.1 6.6 15.0 16.5 12.8 12.7 20.2 8.0 16.4 7.5 12.9 18.2 7.7 TIMM8B "DDP2, FLJ21744, MGC102866, MGC117373, TIM8B" ENSG00000150779 "Translocase of inner mitochondrial membrane 8 homolog B" Q9Y5J9 11 112084800-112086798 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 577.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041173 Approved NA NA 11000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA041173: AB_10796340" "unprognostic (1.36e-1)" "unprognostic (8.82e-2)" "unprognostic (1.19e-2)" "unprognostic (1.56e-3)" "unprognostic (6.45e-2)" "unprognostic (2.79e-2)" "unprognostic (4.38e-2)" "unprognostic (5.54e-2)" "unprognostic (1.19e-2)" "unprognostic (2.40e-3)" "unprognostic (8.17e-2)" "unprognostic (4.81e-2)" "unprognostic (3.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.48e-1)" "unprognostic (3.29e-2)" "unprognostic (2.44e-2)" 35.2 55.8 35.0 23.3 36.1 34.9 30.9 37.5 49.0 27.3 36.4 31.2 19.0 22.0 25.2 65.7 19.6 9.0 137.9 35.8 36.3 38.0 51.2 21.2 21.2 36.3 35.6 18.2 21.9 24.1 22.1 17.5 35.6 25.1 23.7 15.6 28.3 17.7 106.5 34.6 23.3 20.1 36.3 27.6 27.8 31.9 36.4 29.6 21.4 97.9 22.5 27.2 32.3 36.5 43.4 56.0 105.5 89.6 45.0 27.7 50.6 43.8 29.3 55.4 54.6 198.2 53.4 19.3 96.0 53.5 46.9 57.9 82.6 61.5 29.0 55.0 116.0 86.7 77.4 125.6 70.1 98.8 45.3 53.5 28.3 59.4 20.6 20.6 84.9 84.4 74.5 86.2 52.5 114.8 75.9 113.9 52.3 126.0 97.4 65.5 49.5 121.6 107.5 118.6 85.1 61.9 71.6 100.9 33.5 47.5 123.5 75.1 62.5 58.6 77.8 48.6 54.1 30.7 73.5 137.7 21.0 97.6 55.9 100.8 146.8 157.0 54.5 156.2 52.6 91.1 55.8 53.0 157.2 85.8 64.7 54.4 80.3 93.2 133.4 213.2 91.1 113.6 35.0 36.1 37.5 49.0 35.8 36.3 36.3 35.6 35.6 36.3 36.4 36.5 83.5 54.5 41.1 6.8 66.3 82.7 69.3 247.1 66.6 44.6 136.2 167.3 577.5 178.7 142.1 101.2 31.3 222.2 78.9 257.3 360.0 229.6 96.1 103.4 141.4 94.0 142.7 118.9 7.7 227.3 184.5 100.0 95.3 124.8 60.9 90.5 110.3 444.8 297.2 33.7 8.8 166.9 185.1 138.9 76.3 181.0 98.8 115.3 168.9 2.8 185.5 125.6 116.4 4.5 12.0 220.0 210.3 88.8 106.0 107.4 195.8 515.8 96.2 69.0 72.3 63.4 132.8 193.9 158.9 224.2 148.6 129.7 54.8 185.9 208.6 94.0 TIMMDC1 "C3orf1, FLJ22597" ENSG00000113845 "Translocase of inner mitochondrial membrane domain containing 1" Q9NPL8 3 119498547-119525090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053214, HPA055846" Uncertain Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA053214: AB_2682081, HPA055846: AB_2682941" "unprognostic (3.95e-2)" "unprognostic (8.85e-2)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (9.60e-2)" "unprognostic (6.25e-2)" "unprognostic (3.39e-1)" "unprognostic (4.67e-3)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (8.89e-2)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-1)" 10.5 12.0 13.4 10.7 14.3 6.3 13.1 14.2 15.4 15.0 13.2 11.3 8.9 9.3 17.9 15.9 12.8 14.4 44.0 12.7 13.9 17.8 14.2 11.0 17.7 14.3 13.6 10.9 11.1 23.1 7.1 17.1 13.9 13.0 13.7 4.2 14.6 19.7 27.3 15.8 7.7 12.1 14.0 9.9 8.5 10.6 14.1 11.4 19.1 49.2 14.8 14.2 7.0 14.6 26.9 24.5 12.4 10.4 45.5 30.6 27.0 7.7 25.3 21.7 24.7 16.7 16.0 19.5 13.7 27.1 15.1 12.2 30.8 24.8 35.0 16.4 10.9 14.4 10.7 18.8 23.9 11.3 9.1 28.0 37.4 18.4 22.4 13.9 31.5 18.5 19.8 18.1 40.3 33.2 12.0 23.7 16.2 22.4 30.1 10.0 8.4 25.4 32.0 13.1 15.8 29.4 7.8 11.8 28.0 16.2 19.5 30.4 16.1 12.2 9.3 11.3 13.8 12.1 11.8 28.3 20.7 28.5 19.6 11.1 17.6 21.3 10.8 17.6 12.5 16.2 10.4 12.0 17.4 17.6 12.2 10.9 4.3 13.1 20.9 15.1 20.7 22.1 13.4 14.3 14.2 15.4 12.7 13.9 14.3 13.6 13.9 14.0 14.1 14.6 61.2 25.6 39.3 18.6 24.0 37.5 50.4 110.2 31.3 25.0 44.8 55.0 165.3 41.5 63.7 40.5 14.6 157.5 28.9 44.0 150.6 73.2 12.2 39.9 41.1 56.0 28.8 43.1 17.4 62.7 112.7 48.2 29.0 31.1 41.2 34.1 31.8 52.4 86.3 21.9 23.9 43.5 87.5 32.7 40.4 10.0 47.2 39.4 44.4 15.0 65.7 73.6 18.6 22.6 35.6 52.7 40.9 54.5 30.2 43.5 50.5 146.5 63.0 35.4 72.3 43.9 52.5 111.1 58.2 45.9 42.1 177.5 29.7 48.0 45.7 46.7 TLE5 "AES, GRG5" ENSG00000104964 "TLE family member 5, transcriptional modulator" Q08117 19 3052910-3063107 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 92.3;dendritic cells: 167.1;Extravillous trophoblasts: 372.2;Hofbauer cells: 84.2;Plasma cells: 57.5;Syncytiotrophoblasts: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049499 Supported Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA049499: AB_2680795" "unprognostic (1.08e-1)" "unprognostic (3.32e-3)" "unprognostic (7.15e-2)" "prognostic favorable (3.89e-4)" "unprognostic (1.45e-1)" "unprognostic (4.07e-3)" "unprognostic (3.00e-2)" "unprognostic (1.26e-2)" "unprognostic (3.58e-1)" "unprognostic (7.58e-2)" "unprognostic (1.38e-3)" "unprognostic (2.15e-1)" "prognostic favorable (7.74e-4)" "unprognostic (7.17e-3)" "unprognostic (2.60e-1)" "unprognostic (2.08e-2)" "unprognostic (1.78e-3)" 237.7 357.9 325.2 93.8 320.4 99.7 214.8 341.0 435.0 304.3 209.5 466.7 82.0 336.6 80.8 282.1 315.9 90.6 504.4 319.4 327.4 266.5 239.6 283.8 145.2 341.8 301.7 284.0 234.4 174.5 276.9 94.7 349.4 314.8 90.9 82.9 287.9 197.1 550.0 231.4 233.2 109.9 279.3 325.2 274.2 109.0 345.5 210.0 315.9 313.7 120.0 361.8 285.4 326.0 120.8 138.7 101.8 180.7 122.1 140.8 78.9 155.1 211.9 192.6 173.0 57.2 120.3 195.9 169.1 200.7 69.5 100.6 122.9 226.7 112.6 292.8 56.5 68.8 141.9 109.6 217.1 99.4 85.1 152.3 182.1 93.2 89.7 226.9 191.8 100.8 245.5 80.0 169.0 120.0 221.7 119.5 89.4 85.3 140.3 251.3 123.4 135.1 241.7 247.7 258.1 283.3 152.2 174.1 163.9 55.8 138.3 134.2 266.5 161.1 106.6 152.8 143.5 4.7 0.9 265.0 151.1 165.7 151.7 38.9 6.6 18.1 130.8 10.7 100.8 62.0 169.3 134.9 12.5 74.3 220.8 149.5 4.6 41.6 9.2 28.8 242.0 89.2 325.2 320.4 341.0 435.0 319.4 327.4 341.8 301.7 349.4 279.3 345.5 326.0 92.3 0.0 0.0 0.0 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 24.5 167.1 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 372.2 27.7 0.0 0.0 0.0 0.0 0.0 0.0 84.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 94.0 27.8 0.0 0.0 0.0 TLN2 "ILWEQ, KIAA0320" ENSG00000171914 "Talin 2" Q9Y4G6 15 62390526-62844631 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 38.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.7;Inhibitory neurons: 127.2;Microglial cells: 139.6;Oligodendrocyte precursor cells: 108.6;Oligodendrocytes: 93.6;Skeletal myocytes: 135.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 59.3;hTERT-HME1: 48.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017194, HPA051828, HPA054787" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 46000000 "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites, Cytosol" "CAB017194: , HPA051828: AB_2732570, HPA054787: AB_2732587" "prognostic favorable (6.53e-4)" "unprognostic (2.61e-1)" "unprognostic (9.47e-2)" "unprognostic (8.95e-2)" "unprognostic (3.74e-1)" "unprognostic (1.43e-1)" "unprognostic (8.24e-2)" "unprognostic (9.94e-2)" "unprognostic (1.68e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (1.91e-1)" "prognostic favorable (1.81e-6)" "prognostic favorable (7.74e-4)" "unprognostic (1.34e-1)" "unprognostic (5.79e-2)" "unprognostic (2.30e-1)" 19.0 4.1 14.2 2.2 15.6 3.8 10.4 3.2 16.9 8.0 20.2 9.3 4.7 3.7 2.1 2.1 4.3 1.9 12.1 18.3 8.2 38.4 4.8 2.4 0.5 7.6 8.2 4.6 4.7 2.4 5.5 1.2 6.2 2.3 7.3 7.7 7.8 2.1 26.1 3.6 5.1 2.9 11.2 1.3 5.5 5.4 7.0 3.1 13.0 12.2 0.5 4.1 4.2 13.8 1.8 5.6 8.0 9.4 59.3 5.6 9.0 13.7 10.8 12.4 12.2 15.1 1.9 4.8 6.2 24.0 20.5 2.4 10.3 2.2 10.8 15.2 1.0 0.6 22.8 10.1 2.0 1.6 0.4 10.3 5.6 16.6 48.9 7.1 0.5 5.7 0.6 0.2 21.0 7.5 0.7 0.6 14.2 26.3 4.1 5.8 20.3 5.8 6.5 11.6 1.9 9.3 10.6 1.1 3.5 17.1 2.9 3.6 3.9 22.2 30.0 36.3 35.6 0.3 0.9 3.1 10.1 3.4 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 15.6 3.2 16.9 18.3 8.2 7.6 8.2 6.2 11.2 7.0 13.8 11.5 0.0 3.2 50.6 1.1 2.4 1.8 0.7 1.2 18.6 16.5 10.2 41.1 5.7 0.9 27.6 37.5 1.2 0.7 39.0 11.7 3.5 4.3 10.9 14.3 9.0 2.4 37.7 153.7 3.9 29.7 21.5 40.8 17.4 0.0 9.3 3.3 12.6 4.9 48.8 127.2 20.0 6.1 6.2 3.1 5.2 11.8 5.5 0.0 139.6 0.8 11.1 1.0 108.6 93.6 3.7 21.0 15.8 0.7 1.5 14.6 35.1 0.1 48.3 0.0 135.6 12.3 6.7 24.5 3.1 1.6 1.4 1.3 25.8 37.7 1.7 TMEM120A "NET29, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 289.1;Late spermatids: 1002.1;Proximal enterocytes: 414.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.78e-2)" "unprognostic (3.35e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.26e-1)" "unprognostic (2.75e-3)" "unprognostic (6.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.15e-2)" 54.4 95.0 33.9 11.0 32.7 13.9 44.4 36.9 40.6 33.1 33.2 33.7 50.6 22.6 21.6 31.8 32.0 16.6 111.9 32.3 34.4 38.9 84.7 25.0 10.1 57.6 36.1 56.1 43.2 17.4 20.0 15.6 61.5 26.5 14.8 6.1 24.7 23.3 79.3 18.5 63.4 11.0 31.2 28.2 44.3 77.1 34.7 8.0 19.4 94.4 12.0 32.9 27.3 31.8 10.3 15.3 7.7 61.7 52.1 35.1 16.9 10.0 27.8 13.7 17.2 26.8 14.3 4.8 7.6 30.4 39.1 11.8 7.6 10.3 4.7 9.0 8.5 5.2 10.6 38.2 50.6 2.1 32.6 37.5 9.2 10.1 12.2 14.3 22.4 8.7 9.8 7.9 24.5 18.5 3.3 32.6 3.5 23.7 16.3 3.5 7.8 23.6 28.2 9.3 3.8 18.0 11.4 32.5 16.7 19.1 22.7 15.4 12.8 38.1 12.0 22.1 8.6 8.5 7.0 2.2 20.7 5.3 8.9 106.6 58.0 109.5 26.4 53.7 20.0 15.8 21.7 20.5 27.2 17.9 15.1 14.8 223.0 31.2 55.2 10.7 50.9 46.5 33.9 32.7 36.9 40.6 32.3 34.4 57.6 36.1 61.5 31.2 34.7 31.8 22.4 22.4 12.3 12.7 14.1 0.0 18.1 0.0 18.8 5.6 36.2 22.2 112.7 51.5 8.6 27.6 6.2 20.9 17.6 133.9 25.4 50.3 289.1 9.8 29.3 21.4 8.4 11.4 4.1 38.9 16.2 36.0 31.1 18.1 24.6 172.6 29.3 115.6 36.1 11.8 7.2 40.5 0.0 34.2 0.0 1002.1 40.4 36.0 0.0 3.7 23.7 12.8 18.6 4.0 7.3 40.0 108.9 30.9 24.6 17.4 414.8 118.0 4.4 7.0 39.5 46.0 31.2 113.4 15.4 33.1 0.0 10.9 20.0 31.0 43.6 28.1 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TMEM129 D4S2561E ENSG00000168936 "Transmembrane protein 129, E3 ubiquitin ligase" A0AVI4 4 1715952-1721358 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Unfolded protein response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.07e-2)" "unprognostic (1.54e-1)" "unprognostic (2.12e-1)" "unprognostic (2.85e-1)" "unprognostic (4.04e-2)" "unprognostic (1.22e-3)" "unprognostic (7.35e-3)" "unprognostic (4.82e-2)" "unprognostic (2.27e-1)" "unprognostic (2.94e-2)" "unprognostic (2.51e-3)" "unprognostic (2.81e-1)" "prognostic favorable (9.64e-8)" "unprognostic (1.47e-1)" "unprognostic (6.49e-2)" "unprognostic (3.08e-1)" "unprognostic (2.36e-3)" 20.8 33.7 30.2 11.0 31.2 6.1 20.6 30.2 30.7 23.7 37.1 34.4 22.0 27.8 10.1 25.0 26.7 11.8 38.6 27.9 28.1 41.2 46.9 21.7 13.0 35.0 32.6 25.8 36.9 33.2 43.0 10.2 29.5 29.6 8.5 6.4 32.9 19.1 30.9 20.3 26.1 9.5 33.2 25.9 31.6 15.4 32.2 8.1 35.5 18.7 8.2 27.0 19.8 30.1 16.1 18.4 15.0 22.4 27.0 15.7 17.3 12.7 20.4 13.0 13.9 13.6 38.8 20.9 14.9 13.7 23.1 15.8 7.7 16.2 2.2 14.5 23.1 11.9 13.9 17.5 22.0 16.4 19.9 26.1 34.2 7.1 6.5 30.1 20.3 19.4 13.2 15.1 12.4 12.6 22.4 26.5 23.3 17.6 22.4 14.3 7.9 26.0 32.6 17.6 34.7 21.4 10.9 19.0 17.3 5.3 39.3 7.5 14.0 15.0 11.3 13.3 12.5 37.7 12.1 10.0 17.3 22.2 16.4 0.1 1.7 0.0 1.6 1.1 1.4 0.7 1.4 1.2 1.6 0.9 1.0 0.7 0.3 1.0 1.2 3.7 0.7 1.1 30.2 31.2 30.2 30.7 27.9 28.1 35.0 32.6 29.5 33.2 32.2 30.1 13.2 22.4 9.3 17.0 11.4 5.1 15.2 9.6 13.6 27.2 15.4 13.0 12.9 18.6 6.6 23.9 6.2 20.9 26.8 28.8 25.4 20.4 1.1 7.9 8.2 12.4 13.1 8.6 7.3 19.6 7.8 17.4 12.8 8.4 10.2 14.7 15.4 19.9 17.9 25.2 9.0 26.5 14.2 11.7 4.9 3.1 30.4 8.7 10.6 13.1 7.2 39.6 25.7 8.0 11.9 14.1 14.9 36.1 13.1 16.8 24.0 18.4 7.9 19.7 13.1 21.9 17.1 7.1 5.6 13.7 9.5 5.5 12.1 22.7 33.8 11.3 TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 580.8;Distal tubular cells: 626.1;Intestinal goblet cells: 547.5;Paneth cells: 682.0;Proximal enterocytes: 633.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 228.2;T-47d: 221.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Cell Junctions" "HPA014615: AB_2204756, HPA050244: AB_2681061" "unprognostic (2.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.53e-3)" "unprognostic (1.52e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.24e-1)" "unprognostic (8.45e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" 32.7 44.1 37.9 23.3 40.1 40.2 48.7 43.8 42.6 36.4 39.7 120.5 48.4 25.2 63.6 109.6 48.2 27.9 74.0 36.8 41.3 116.8 134.7 39.3 21.1 42.1 40.2 33.4 74.0 83.0 62.2 41.9 44.4 132.3 112.2 12.2 61.5 28.5 38.1 68.7 60.6 22.4 40.0 38.7 76.2 33.1 41.1 29.8 66.3 35.8 26.4 39.2 49.5 44.1 55.0 35.9 34.9 21.1 42.2 34.1 69.9 30.8 47.4 35.9 29.0 47.9 47.5 53.4 44.1 32.5 32.0 78.2 14.0 87.8 11.6 38.7 27.5 30.4 18.0 52.3 60.8 31.1 35.5 33.1 146.4 26.7 79.0 42.3 54.6 67.4 28.9 26.7 48.2 102.0 42.0 21.2 16.7 228.2 43.8 34.6 37.6 156.1 82.1 28.4 55.3 25.7 32.9 125.7 35.1 27.1 221.4 28.9 38.5 24.6 19.9 46.3 19.5 17.0 29.7 28.2 39.9 44.2 37.2 19.5 29.5 20.4 23.1 44.2 20.6 18.2 15.1 16.0 24.1 23.0 20.6 19.5 7.3 29.9 37.4 90.6 16.4 29.1 37.9 40.1 43.8 42.6 36.8 41.3 42.1 40.2 44.4 40.0 41.1 44.1 62.0 57.7 79.0 6.5 39.6 40.7 99.3 120.5 55.2 13.8 128.7 152.9 42.3 124.4 100.9 117.7 8.4 182.4 64.0 580.8 626.1 179.2 48.4 80.1 50.4 48.5 206.9 53.6 8.2 78.5 141.7 59.1 76.5 148.2 41.8 67.5 56.0 171.7 148.5 5.0 6.4 547.5 109.9 61.6 29.8 134.9 37.6 53.7 85.4 2.8 85.7 61.1 78.2 2.5 11.7 90.1 682.0 29.7 34.8 193.7 633.0 459.2 60.9 30.0 46.0 32.4 46.9 57.2 53.5 156.7 62.8 274.3 42.7 65.1 460.1 125.9 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM178B DKFZp547G036 ENSG00000261115 "Transmembrane protein 178B" H3BS89 7 141074064-141480380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 11.3;parathyroid gland: 11.9;tongue: 12.2" "Group enriched" "Detected in many" 5 "Astrocytes: 175.0;Excitatory neurons: 584.8;Inhibitory neurons: 566.2;Oligodendrocyte precursor cells: 306.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 6.0;HDLM-2: 5.7;NTERA-2: 5.1;RPTEC TERT1: 8.2;SCLC-21H: 6.4;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048771 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoli "HPA048771: AB_2680517" "unprognostic (7.33e-3)" "unprognostic (2.02e-2)" "unprognostic (2.83e-2)" "unprognostic (7.79e-4)" "unprognostic (1.94e-1)" "unprognostic (1.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.69e-2)" "unprognostic (6.94e-2)" "unprognostic (2.21e-2)" "unprognostic (7.17e-4)" "unprognostic (1.05e-1)" "prognostic favorable (4.10e-4)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (5.35e-3)" "unprognostic (8.98e-2)" 0.3 1.4 3.7 0.6 5.4 0.0 0.5 0.2 7.4 0.3 0.0 0.8 0.0 0.8 0.4 0.7 0.3 0.3 11.3 7.0 5.0 1.3 0.0 0.3 1.4 1.5 5.9 0.1 0.9 11.9 4.2 0.0 5.6 2.3 0.3 5.5 1.2 0.5 4.6 0.2 0.4 1.0 0.6 0.7 0.3 0.5 5.2 1.4 8.5 12.2 3.1 0.5 0.2 1.9 0.0 0.1 0.0 0.0 0.5 0.2 1.5 0.1 2.3 0.7 0.8 0.0 0.0 1.9 2.0 0.1 0.5 0.0 6.0 0.0 1.9 5.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 5.1 0.0 0.0 0.4 0.9 2.6 8.2 2.4 6.4 3.9 0.1 0.2 0.9 1.2 0.8 0.0 0.0 0.1 0.9 2.7 0.0 0.0 0.0 0.0 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.4 0.2 7.4 7.0 5.0 1.5 5.9 5.6 0.6 5.2 1.9 1.3 0.0 0.0 175.0 0.0 0.5 0.7 0.9 0.6 25.5 1.4 0.5 48.7 0.0 1.3 1.8 2.1 0.0 0.0 0.0 1.9 0.1 1.3 0.2 0.1 1.2 0.0 0.0 584.8 0.4 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.1 30.3 566.2 0.0 2.0 0.0 0.0 1.6 0.0 0.1 1.8 24.4 0.0 4.2 0.0 306.1 81.3 0.8 0.0 0.7 0.0 2.2 0.0 3.4 0.2 1.8 0.0 3.9 0.8 1.4 0.7 2.9 0.1 0.3 0.3 0.2 0.1 2.0 TMEM182 FLJ30294 ENSG00000170417 "Transmembrane protein 182" Q6ZP80 2 102736905-103019900 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "heart muscle: 97.6;skeletal muscle: 150.7;tongue: 127.7" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 150.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045861 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" "HPA045861: AB_2679475" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (5.10e-2)" "unprognostic (1.12e-4)" "unprognostic (5.35e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-1)" "unprognostic (4.19e-2)" "unprognostic (3.42e-2)" "unprognostic (9.88e-2)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-1)" "unprognostic (2.36e-2)" 2.7 1.6 2.2 0.7 2.0 0.6 2.3 2.6 2.9 2.9 2.2 1.8 1.9 1.1 5.3 3.9 2.1 1.8 97.6 2.5 3.1 2.1 2.0 1.3 1.8 2.8 2.7 1.5 2.1 3.6 2.6 1.4 3.0 4.0 2.3 1.5 2.0 2.1 150.7 0.5 1.2 1.1 2.5 1.6 2.2 1.4 2.6 1.8 3.0 127.7 1.4 2.2 0.6 2.7 4.9 3.3 2.4 7.3 2.8 2.4 6.9 2.5 2.2 2.4 4.4 10.7 7.3 4.5 9.0 1.4 6.1 3.3 2.6 3.7 5.4 11.6 3.5 6.6 1.4 6.7 3.0 6.2 4.4 3.2 7.6 4.5 5.2 1.9 0.4 6.4 5.2 1.2 3.5 4.6 3.9 5.7 4.2 5.9 3.6 3.4 6.3 3.7 5.7 6.2 5.2 1.9 4.1 3.3 10.3 3.5 3.0 3.2 0.7 4.2 3.5 2.7 3.1 3.9 13.0 5.5 3.8 8.4 6.3 0.0 0.0 0.2 2.5 0.2 2.8 3.6 1.5 1.3 0.9 1.2 2.4 2.4 0.0 2.4 0.3 2.9 0.5 1.1 2.2 2.0 2.6 2.9 2.5 3.1 2.8 2.7 3.0 2.5 2.6 2.7 0.6 22.4 12.3 1.3 3.6 0.4 1.0 1.8 1.2 0.3 8.1 2.4 150.6 0.0 15.3 3.7 0.0 2.3 4.2 0.5 0.0 1.8 0.6 2.4 1.1 2.0 6.6 3.6 6.1 3.3 2.6 6.9 4.1 1.6 3.8 1.2 0.7 2.3 1.2 0.0 10.8 2.6 2.0 0.8 0.7 0.6 0.6 1.3 7.2 6.5 0.1 2.4 1.0 8.5 3.4 2.4 1.1 0.7 2.7 1.0 1.0 2.4 12.8 0.3 0.0 4.6 2.3 1.0 2.4 2.5 0.6 1.1 2.9 1.1 1.8 2.8 TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 219.8;skin 1: 64.7;vagina: 80.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 104.7;Cytotrophoblasts: 128.3;Macrophages: 121.3;Squamous epithelial cells: 116.5;Suprabasal keratinocytes: 201.9;Syncytiotrophoblasts: 656.6;Urothelial cells: 157.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 244.9;hTCEpi: 56.1;hTERT-HME1: 68.0;RT4: 36.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved Cytosol NA NA 2500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" 0.1 0.1 0.4 0.0 0.4 3.3 3.2 0.5 0.6 42.1 0.3 0.0 0.1 0.1 1.3 219.8 3.1 0.1 4.2 0.5 0.3 0.2 0.3 2.1 0.1 0.4 0.3 0.1 0.1 3.2 0.2 15.9 0.3 3.7 0.0 0.1 27.3 2.5 1.3 64.7 0.0 0.1 0.1 1.8 0.2 0.8 0.4 1.5 0.1 0.6 25.9 15.2 80.1 0.3 26.6 0.1 0.0 0.1 0.0 0.0 22.4 0.2 1.1 1.3 1.4 1.0 4.1 0.1 0.2 0.0 0.6 7.6 0.0 244.9 5.1 0.2 0.0 1.9 0.2 0.8 0.0 0.0 0.0 0.0 56.1 0.0 68.0 0.4 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 0.2 4.3 0.0 1.6 0.0 1.6 36.0 0.2 0.2 0.1 31.3 0.0 4.6 2.8 0.7 0.0 0.0 1.6 0.0 2.1 0.3 0.1 0.4 0.1 0.0 0.0 1.6 0.9 1.1 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 6.0 0.0 0.0 0.8 0.0 32.9 0.4 0.4 0.5 0.6 0.5 0.3 0.4 0.3 0.3 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.3 64.2 104.7 71.7 17.6 0.0 1.5 5.6 4.7 0.0 39.4 1.8 0.0 128.3 0.0 0.1 0.0 0.5 0.8 2.9 0.0 1.8 0.0 0.0 0.3 0.0 14.7 1.8 0.0 0.1 0.0 0.0 2.2 0.7 10.8 0.0 0.3 0.0 12.2 4.8 7.3 2.0 0.3 121.3 10.6 0.0 2.6 0.0 2.1 0.0 0.2 2.2 0.0 0.0 0.0 53.5 0.0 0.0 55.0 0.0 0.0 0.1 3.6 0.7 6.8 116.5 201.9 656.6 1.0 0.2 0.0 157.9 TMEM63C "C14orf171, CSC1, DKFZp434P0111, hsCSC1" ENSG00000165548 "Transmembrane protein 63C" Q9P1W3 14 77116568-77259495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7;pituitary gland: 41.9" "Cell type enhanced" "Detected in some" "Early spermatids: 9.5;Enteroendocrine cells: 19.2;Excitatory neurons: 25.8;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 16.1" "Cancer enhanced" "Detected in many" "breast cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.5;Karpas-707: 24.1;RPMI-8226: 12.7;SCLC-21H: 32.5;SK-BR-3: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030657 Uncertain Approved Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "HPA030657: AB_10601699" "unprognostic (2.74e-1)" "unprognostic (1.79e-2)" "unprognostic (2.30e-1)" "unprognostic (4.30e-8)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (2.68e-3)" "unprognostic (1.61e-3)" "unprognostic (2.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.90e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.34e-7)" "unprognostic (5.90e-3)" 0.2 9.6 9.2 0.6 5.9 0.8 3.3 28.7 10.5 2.6 0.0 4.5 1.2 0.1 4.5 6.4 0.2 0.2 0.9 5.6 24.6 0.5 0.1 0.5 0.3 4.5 8.3 0.1 4.8 1.5 41.9 0.7 16.9 0.2 3.0 2.4 2.7 0.0 0.5 9.7 2.7 0.6 4.2 3.3 1.9 11.3 18.2 0.1 2.2 0.4 0.3 0.0 7.1 4.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 18.5 3.4 0.0 3.0 2.5 3.8 1.5 0.0 1.2 1.4 0.3 1.8 0.0 0.0 3.2 0.1 0.0 7.5 0.0 0.2 0.0 0.0 8.7 0.0 24.1 0.0 9.3 2.6 0.1 0.8 0.0 0.0 0.0 1.2 12.7 0.3 0.0 32.5 4.9 0.4 29.1 0.0 0.6 2.8 1.6 0.0 0.0 5.9 0.0 0.0 1.9 0.1 0.7 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 0.1 9.2 5.9 28.7 10.5 5.6 24.6 4.5 8.3 16.9 4.2 18.2 4.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 3.3 2.2 0.8 0.7 0.0 1.7 0.0 2.1 0.0 1.5 3.8 1.9 0.0 9.5 0.3 0.4 0.1 19.2 0.0 25.8 0.2 0.1 0.3 0.0 2.4 0.0 0.2 0.0 0.0 2.7 3.3 22.2 3.0 4.1 0.0 0.0 6.2 0.0 0.2 0.0 3.7 0.6 0.3 0.0 16.1 1.1 0.2 7.0 0.4 0.1 0.0 0.5 0.2 0.1 0.6 0.0 0.0 0.3 0.6 0.1 2.4 0.0 0.0 0.2 0.7 0.7 0.1 TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7;Excitatory neurons: 59.8;Respiratory ciliated cells: 95.8;Rod photoreceptor cells: 83.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (3.08e-1)" "unprognostic (2.25e-5)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.51e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (8.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" 2.4 2.5 1.7 1.3 2.7 1.4 3.5 2.8 2.7 3.6 10.3 2.1 1.4 4.2 6.3 1.8 13.3 2.8 5.0 2.5 3.0 3.1 1.2 3.6 1.4 6.5 6.8 4.2 2.6 4.7 5.8 2.1 3.1 2.8 2.2 6.1 1.9 3.2 1.2 3.7 1.3 2.4 3.5 1.9 2.0 6.8 3.1 1.4 6.0 0.6 1.7 2.5 2.2 3.9 5.8 3.7 5.2 4.1 4.4 9.8 3.1 3.3 5.4 3.8 7.5 2.1 13.0 1.5 6.9 3.6 6.9 5.9 1.9 3.3 5.6 1.1 4.3 3.6 4.8 1.8 4.0 2.7 1.5 4.2 3.0 6.8 3.0 7.1 4.0 6.1 2.5 0.9 4.0 1.4 4.5 2.0 4.3 2.3 3.4 1.6 1.7 0.0 4.7 2.5 3.4 5.7 3.3 0.9 5.6 4.6 6.8 1.4 2.1 4.1 1.7 5.7 3.0 1.8 5.5 1.6 7.4 0.8 3.9 1.7 0.5 0.2 1.5 0.2 1.2 0.7 1.3 1.3 1.0 1.5 1.5 1.5 0.5 1.8 0.2 1.1 0.3 0.5 1.7 2.7 2.8 2.7 2.5 3.0 6.5 6.8 3.1 3.5 3.1 3.9 5.0 12.8 8.7 27.4 6.3 2.8 5.6 12.2 2.2 14.6 6.0 5.6 31.9 5.7 12.5 20.2 66.7 3.4 5.6 1.2 0.0 6.4 24.5 50.9 15.1 6.8 9.0 4.6 59.8 2.7 5.6 9.8 4.1 4.9 5.1 16.1 10.0 1.6 2.2 23.5 34.2 2.4 8.2 2.9 2.6 7.7 16.1 1.8 1.8 13.1 1.5 9.3 3.1 17.6 3.4 2.1 0.5 10.5 2.7 2.1 0.4 3.9 95.8 83.2 6.6 18.9 6.9 47.6 16.5 2.6 1.4 2.3 5.6 13.7 2.8 1.6 TNFRSF13C "BAFFR, CD268" ENSG00000159958 "TNF receptor superfamily member 13C" Q96RJ3 22 41922032-41926806 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 33.8;lymphoid tissue: 58.1" "Cell type enriched" "Detected in some" 10 "B-cells: 194.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 36 "memory B-cell: 22.5;naive B-cell: 29.1" "Lineage enriched" "Detected in single" 40 "B-cells: 29.1" "Group enriched" "Detected in some" 6 "REH: 21.0;U-698: 10.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA003246, CAB008380" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "CAB008380: AB_590602, HPA003246: AB_1078264" "unprognostic (3.43e-4)" "prognostic favorable (4.44e-7)" "unprognostic (6.52e-2)" "unprognostic (9.10e-2)" "unprognostic (7.64e-3)" "unprognostic (4.83e-3)" "unprognostic (2.89e-2)" "unprognostic (3.78e-3)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (2.51e-2)" "unprognostic (1.66e-1)" "unprognostic (4.79e-8)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" "unprognostic (1.77e-1)" "unprognostic (9.44e-2)" 0.8 0.8 2.1 17.7 1.3 6.0 0.5 1.6 1.9 0.2 0.6 2.1 1.2 0.3 0.3 1.5 0.4 1.0 0.4 1.9 2.0 0.8 0.3 1.0 39.0 3.6 2.1 0.1 0.1 0.1 0.2 0.3 2.2 0.5 1.1 0.4 1.7 0.1 2.3 3.3 33.8 0.1 2.7 58.1 2.5 0.7 2.1 3.4 1.1 0.5 54.6 1.8 0.5 2.0 0.3 0.2 1.1 2.3 0.0 0.0 0.4 0.2 0.1 0.2 0.8 0.9 0.5 1.9 0.4 0.2 0.2 0.4 0.7 0.0 0.3 0.4 2.3 0.2 0.4 0.2 0.1 1.7 0.4 0.1 0.0 0.4 0.1 0.1 0.0 0.7 0.4 1.9 0.2 0.7 1.6 1.8 0.7 0.1 0.1 21.0 2.4 1.6 0.0 0.2 1.3 0.3 0.1 0.4 0.3 0.2 0.4 2.2 0.2 0.5 2.5 0.9 0.3 2.0 1.1 10.9 0.1 1.8 0.5 0.7 0.1 0.2 0.2 0.2 0.3 22.5 0.3 0.2 0.1 29.1 0.4 0.4 0.3 0.3 0.3 0.4 0.2 1.1 2.1 1.3 1.6 1.9 1.9 2.0 3.6 2.1 2.2 2.7 2.1 2.0 0.1 0.0 1.1 0.0 194.5 0.1 0.4 0.0 1.2 1.0 1.6 1.3 1.4 0.0 0.0 0.0 0.0 0.2 2.6 0.3 0.0 0.0 0.1 2.6 0.5 0.3 1.2 0.4 0.0 0.0 0.2 0.7 0.5 4.3 0.0 1.5 0.0 0.2 0.1 8.4 0.1 0.1 0.0 0.6 0.0 0.0 0.0 1.3 0.0 6.5 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 18.0 0.3 0.1 0.2 0.0 0.4 0.0 0.5 0.4 1.5 1.4 0.3 0.0 0.1 3.4 0.2 0.4 0.2 TNNI3 "CMD2A, CMH7, TNNC1" ENSG00000129991 "Troponin I3, cardiac type" P19429 19 55151767-55157773 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 622 "heart muscle: 10813.5" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 12618.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 13.0;HMC-1: 20.3;K-562: 39.1;OE19: 54.6" "Region enhanced" "Detected in many" "olfactory bulb: 10.9" "Low region specificity" "Detected in many" "CAB009349, HPA046428" Enhanced Approved Vesicles,Cytosol NA NA 2400000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Vesicles "CAB009349: AB_793465, HPA046428: AB_2679661" "unprognostic (2.12e-2)" "unprognostic (3.05e-2)" "unprognostic (2.44e-2)" "unprognostic (1.36e-1)" "unprognostic (2.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.37e-3)" "unprognostic (2.13e-1)" "unprognostic (9.62e-3)" "unprognostic (9.40e-2)" "unprognostic (3.34e-2)" "unprognostic (2.17e-3)" "unprognostic (4.02e-3)" "unprognostic (8.89e-2)" "unprognostic (8.54e-2)" "unprognostic (1.05e-1)" "unprognostic (9.82e-2)" 1.1 3.0 0.3 0.0 0.5 0.0 17.3 0.2 0.4 0.7 0.7 0.7 0.0 0.3 0.1 0.8 6.2 0.9 10813.5 0.6 0.2 1.0 1.1 7.3 1.6 0.5 2.8 1.4 2.3 0.2 0.6 1.0 1.3 2.4 0.0 0.2 1.3 0.0 6.5 1.2 0.6 0.0 0.6 0.4 0.7 3.7 0.3 0.1 1.5 2.4 0.0 0.4 0.6 0.3 1.2 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.4 0.0 0.3 1.8 6.3 0.0 1.1 1.1 1.2 0.3 0.0 0.0 13.0 3.0 0.0 1.9 0.5 0.0 20.3 0.0 0.6 0.1 0.3 0.1 0.1 0.8 39.1 0.8 0.0 0.6 0.2 0.0 0.7 54.6 0.5 1.9 0.4 0.1 1.8 0.0 0.1 2.2 0.0 0.0 0.2 0.0 2.8 9.5 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.6 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.2 0.4 0.6 0.2 0.5 2.8 1.3 0.6 0.3 0.3 0.1 0.0 0.0 0.0 0.2 6.9 0.0 0.8 13.6 0.0 1.0 0.9 12618.4 8.6 1.8 5.5 0.0 1.4 0.1 0.4 0.0 0.7 56.2 3.5 0.1 131.3 1.8 0.0 0.0 0.2 0.5 202.7 0.0 1.3 0.0 996.2 0.0 0.0 2.2 1.7 0.2 0.4 2.0 0.3 0.7 222.9 0.3 4.6 1.8 1.9 0.0 4.2 0.0 0.0 0.1 1.0 0.0 1.9 0.0 0.0 0.0 0.1 11.2 0.5 0.0 0.4 123.6 6.4 16.1 0.7 2.8 2.5 0.6 1.2 1.0 0.1 TOM1L2 ENSG00000175662 "Target of myb1 like 2 membrane trafficking protein" Q6ZVM7 17 17843511-17972422 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 180.5;Cone photoreceptor cells: 158.4;Oligodendrocytes: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022541, HPA023304" Enhanced Approved "Golgi apparatus,Intermediate filaments" NA NA 73000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Intermediate filaments" "Golgi apparatus" "HPA022541: AB_1858182, HPA023304: AB_1858183" "unprognostic (2.32e-1)" "unprognostic (7.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.25e-2)" "prognostic favorable (1.24e-4)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "prognostic unfavorable (2.58e-4)" "prognostic favorable (1.92e-4)" "unprognostic (3.19e-2)" "prognostic favorable (6.21e-9)" "unprognostic (7.11e-2)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (4.51e-2)" 20.7 30.5 64.0 9.5 62.7 6.1 20.3 52.7 70.0 31.9 21.3 44.2 14.0 33.2 11.0 64.4 26.6 13.0 141.0 66.0 56.4 31.3 13.9 23.2 7.7 91.5 80.3 32.9 19.7 40.3 42.2 9.0 95.3 37.3 13.8 50.2 21.3 28.7 67.1 59.7 20.9 23.3 49.7 16.6 34.9 39.4 74.6 8.8 48.5 55.4 12.9 31.4 35.1 72.7 27.1 29.0 8.2 6.2 19.1 19.3 14.2 43.3 20.1 22.9 19.3 28.2 17.6 5.0 52.9 40.8 13.3 104.3 6.8 24.1 14.0 7.2 12.7 8.0 28.0 6.0 12.2 2.0 5.2 22.9 16.6 20.5 15.2 19.6 23.3 7.3 3.0 6.9 30.3 27.1 3.6 4.6 1.5 34.4 19.5 4.7 20.7 12.0 32.4 48.1 8.7 8.4 19.5 25.2 15.3 55.9 13.4 3.6 31.8 21.9 6.5 46.0 16.8 6.1 5.1 2.3 26.4 2.7 55.2 10.0 3.3 4.8 2.8 1.0 2.0 1.6 2.6 2.4 1.6 2.2 4.3 3.2 12.8 1.4 3.3 1.9 1.3 1.7 64.0 62.7 52.7 70.0 66.0 56.4 91.5 80.3 95.3 49.7 74.6 72.7 10.1 32.1 17.0 180.5 9.5 10.8 14.6 13.9 7.4 74.5 20.9 14.1 73.7 15.7 16.6 11.0 158.4 8.5 10.2 43.3 5.9 12.2 30.8 14.1 9.4 12.4 20.4 4.8 63.2 8.7 17.4 12.7 13.3 15.7 2.5 28.1 16.4 13.4 9.2 95.9 74.2 19.2 18.3 8.5 7.6 64.2 26.4 6.4 12.4 35.6 11.8 28.1 10.3 66.9 123.2 16.1 41.0 25.6 8.4 39.1 22.4 11.1 22.9 78.3 19.7 18.0 13.0 16.7 12.1 37.2 17.2 32.2 10.0 30.8 15.4 64.5 TOMM40L "FLJ12770, TOMM40B" ENSG00000158882 "Translocase of outer mitochondrial membrane 40 like" Q969M1 1 161225939-161230746 "Predicted intracellular proteins" "Ion transport, Protein transport, Transport" Porin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 51.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051304 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 41: Macrophages - Immune response" "HPA051304: AB_2681432" "unprognostic (1.18e-2)" "unprognostic (1.58e-2)" "unprognostic (7.65e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.58e-1)" "unprognostic (2.71e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.46e-2)" "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (1.93e-2)" "unprognostic (2.89e-2)" "prognostic favorable (7.80e-4)" "unprognostic (2.29e-1)" "unprognostic (8.71e-2)" "unprognostic (4.61e-2)" "unprognostic (1.14e-1)" 8.5 7.1 11.4 7.2 12.2 14.9 6.7 10.4 17.0 5.3 7.1 11.8 13.9 7.5 2.7 10.1 5.3 4.0 24.3 11.7 9.6 9.9 17.5 7.7 6.7 11.1 11.0 3.6 3.8 15.0 5.8 6.0 11.1 6.4 10.7 11.1 5.8 8.8 23.2 7.2 11.9 8.5 10.5 7.8 8.0 2.2 12.8 7.2 5.7 51.4 7.5 8.6 6.1 11.7 7.6 7.2 11.8 12.9 19.2 10.1 9.1 11.2 13.7 21.6 18.6 41.7 9.8 22.5 13.4 14.9 8.0 9.9 22.6 22.3 12.4 18.9 15.5 21.2 10.5 21.0 8.5 40.8 34.0 11.0 14.0 24.0 12.9 11.0 24.8 23.4 30.0 18.7 15.3 12.3 16.5 6.0 12.9 17.2 20.4 18.7 8.6 21.3 16.2 16.2 28.2 11.8 10.7 30.1 9.9 12.6 23.0 30.9 19.1 11.2 7.7 9.7 16.5 16.5 15.0 16.1 11.6 24.6 11.8 2.5 1.6 1.4 1.0 1.9 1.4 0.8 0.7 1.3 3.0 0.5 0.7 1.7 0.7 1.9 1.5 3.4 1.6 1.5 11.4 12.2 10.4 17.0 11.7 9.6 11.1 11.0 11.1 10.5 12.8 11.7 4.1 0.0 3.3 2.3 3.5 0.5 1.4 1.6 3.4 6.0 2.9 2.3 4.0 1.5 1.7 1.8 6.2 2.4 2.8 8.7 7.9 4.0 4.1 0.7 2.3 4.1 7.7 3.4 5.3 7.8 3.2 3.3 3.6 1.3 3.8 2.2 1.4 7.4 9.7 5.0 5.9 2.6 4.1 5.0 2.7 1.9 2.1 14.8 0.0 1.9 5.6 2.4 4.1 2.0 1.6 4.6 4.1 0.7 4.6 1.1 11.4 5.1 1.2 9.7 0.0 2.2 5.2 0.9 1.8 5.2 1.7 0.8 3.8 3.6 7.0 1.4 TP53INP2 "C20orf110, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH" ENSG00000078804 "Tumor protein p53 inducible nuclear protein 2" Q8IXH6 20 34704339-34713439 "Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 517.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 143.5;Early spermatids: 208.6;Late spermatids: 353.7;Paneth cells: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 13 "granulocytes: 2.7" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 219.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.33e-2)" "unprognostic (2.57e-3)" "unprognostic (1.26e-1)" "unprognostic (3.08e-2)" "unprognostic (2.07e-1)" "unprognostic (1.86e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-1)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (1.52e-2)" "unprognostic (2.57e-2)" "prognostic favorable (1.26e-8)" "unprognostic (8.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.93e-2)" "unprognostic (6.17e-2)" 19.7 28.0 315.7 11.1 439.0 89.7 13.8 343.9 403.1 19.6 159.7 42.2 19.9 26.4 15.7 64.8 19.3 23.8 85.5 233.8 348.8 31.8 45.6 19.6 5.6 517.3 444.7 15.5 16.6 35.1 22.0 10.5 464.6 36.9 38.4 45.9 27.6 31.2 53.1 12.3 23.5 34.7 418.6 6.6 24.4 39.9 376.8 2.9 31.6 94.0 17.2 33.0 23.8 485.7 2.5 3.0 9.8 12.6 22.1 18.1 4.2 9.8 30.9 12.8 10.6 17.3 1.2 7.7 6.6 19.6 25.1 1.9 20.8 4.7 14.0 2.3 2.6 14.0 8.2 16.9 28.6 2.2 10.9 52.3 7.0 10.1 1.4 16.0 20.2 6.9 5.8 24.8 14.5 3.4 1.6 4.8 1.3 2.1 7.4 7.4 6.4 12.4 16.1 8.8 21.4 24.1 8.7 219.0 15.2 11.6 15.8 10.3 15.3 35.0 12.0 4.6 4.1 9.8 12.5 6.2 22.2 31.2 12.5 0.5 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 315.7 439.0 343.9 403.1 233.8 348.8 517.3 444.7 464.6 418.6 376.8 485.7 9.5 3.2 10.6 5.5 8.1 3.7 17.0 11.7 5.7 20.4 17.4 12.3 75.4 15.7 16.7 3.7 52.1 1.7 12.8 143.5 5.9 16.5 208.6 19.6 10.1 10.4 52.4 0.4 4.3 23.9 1.1 9.6 46.9 24.2 7.0 7.5 11.0 28.7 5.3 32.0 6.1 59.5 32.6 10.2 3.6 353.7 7.5 15.5 5.4 2.8 2.6 10.9 0.0 1.0 17.7 24.3 116.1 13.2 7.4 15.3 34.0 8.9 25.1 55.8 19.7 35.9 27.4 4.0 2.7 4.5 3.0 28.5 8.4 9.1 23.9 24.4 TPCN1 "FLJ20612, KIAA1169, TPC1" ENSG00000186815 "Two pore segment channel 1" Q9ULQ1 12 113221050-113298585 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 174.3;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 148.6;hTERT-RPE1: 121.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039757 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA039757: AB_10795156" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.22e-1)" "unprognostic (7.34e-2)" "unprognostic (3.07e-2)" "unprognostic (1.32e-3)" "unprognostic (4.53e-1)" "unprognostic (5.34e-2)" "unprognostic (1.48e-2)" "unprognostic (1.74e-3)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.23e-1)" "unprognostic (9.08e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-3)" 27.7 48.8 37.7 18.2 54.3 12.5 29.1 70.2 40.5 36.9 48.5 30.4 19.4 30.6 19.3 38.4 35.5 21.7 68.0 34.7 33.4 50.9 27.8 29.5 17.0 43.5 48.3 41.5 52.0 30.8 37.9 18.8 46.6 28.7 19.5 11.5 36.1 27.3 36.7 22.2 31.4 18.6 35.4 28.6 19.1 14.5 44.0 8.5 55.5 24.8 18.2 25.3 26.4 45.9 15.3 45.0 5.1 6.5 38.5 43.3 14.9 21.2 148.6 10.9 13.1 33.5 50.7 34.5 30.9 21.6 35.7 18.8 11.9 37.6 14.7 4.1 9.2 12.9 23.5 18.7 49.9 4.5 28.1 41.5 18.6 21.3 37.2 121.7 16.9 9.8 15.0 11.9 13.5 18.3 1.3 68.3 8.4 18.6 22.3 2.5 6.2 67.3 34.9 54.4 6.5 9.8 17.0 43.2 17.1 10.3 13.9 41.4 7.1 16.0 7.8 22.3 13.3 20.0 13.1 29.6 47.2 10.9 12.3 6.9 14.6 1.3 1.8 2.4 2.0 3.4 2.4 2.3 9.9 5.2 3.3 2.1 0.5 8.5 0.3 5.0 1.2 4.7 37.7 54.3 70.2 40.5 34.7 33.4 43.5 48.3 46.6 35.4 44.0 45.9 8.3 9.6 19.6 174.3 9.0 4.6 6.0 15.4 2.8 19.6 17.0 11.2 34.4 12.8 24.4 27.6 16.7 7.2 3.1 35.9 1.9 13.2 13.2 15.0 21.8 8.1 28.8 9.0 24.5 18.7 3.2 20.2 23.0 19.1 31.1 7.7 15.7 18.3 21.5 50.5 26.6 26.8 14.2 17.9 4.7 11.3 21.5 23.7 7.2 79.6 13.7 17.2 3.1 25.1 61.7 11.5 20.3 21.4 4.6 15.9 29.0 19.7 27.9 13.7 0.0 49.8 18.5 3.6 3.3 10.6 4.0 6.6 5.9 13.2 20.3 22.2 TPM1 "C15orf13, CMH3" ENSG00000140416 "Tropomyosin 1" P09493 15 63042632-63071915 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 10621.0;skeletal muscle: 12678.0;tongue: 5183.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 13012.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.7" "Group enriched" "Detected in all" 4 "dendritic cells: 14.1;granulocytes: 48.7;monocytes: 19.2" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 3141.3;SuSa: 3810.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, CAB017698, HPA047089, HPA053624" Supported Approved "Actin filaments,Cytosol" NA NA 120000000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Actin filaments" Cytosol "CAB017698: AB_2272017, HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.00e-2)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (3.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (7.30e-4)" 372.0 103.6 49.8 232.9 53.2 21.6 348.8 52.4 53.9 577.4 59.3 2947.3 289.6 1566.9 250.5 639.0 823.8 288.0 10621.0 53.3 42.2 215.5 94.8 247.1 48.1 42.5 44.3 320.3 383.4 37.5 70.6 206.4 43.7 809.6 523.1 83.9 258.2 1545.5 12678.0 150.7 680.8 1754.9 44.8 134.3 976.5 52.3 50.0 21.1 156.8 5183.6 29.4 1511.0 425.8 42.2 554.5 357.3 418.1 20.9 143.1 89.9 1335.5 1509.1 552.8 905.9 669.2 253.9 107.6 1.7 677.7 1517.1 602.7 295.9 361.8 243.4 597.0 14.5 50.9 81.2 376.3 124.5 403.3 3.8 17.9 125.7 138.0 742.1 198.2 3141.3 243.2 14.7 8.7 20.4 695.3 286.4 25.6 7.1 496.0 129.0 61.1 9.0 146.5 15.8 1308.7 298.8 101.1 71.7 180.9 284.4 65.1 3810.3 204.8 15.3 1095.8 1178.8 572.0 181.6 1094.8 5.9 4.3 7.8 335.9 22.4 842.1 48.7 9.9 4.8 4.0 19.2 3.1 5.5 3.6 4.3 14.1 5.6 4.0 3.6 10.7 1.9 14.3 2.4 6.3 15.6 49.8 53.2 52.4 53.9 53.3 42.2 42.5 44.3 43.7 44.8 50.0 42.2 542.3 57.7 86.3 19.9 12.1 71.9 202.0 344.1 18.2 49.0 450.1 953.1 13012.4 346.0 147.0 318.2 383.7 212.1 20.6 561.3 187.9 2502.6 6.5 147.2 614.4 294.3 267.7 137.0 44.2 1671.1 3094.8 557.1 279.3 211.2 52.0 85.3 175.6 138.1 201.5 52.2 53.2 964.7 183.1 42.5 72.1 27.3 205.0 114.3 81.8 111.5 47.5 47.4 28.8 36.2 6.0 2372.3 623.4 1130.3 8.8 244.3 724.7 361.1 104.2 447.5 1038.7 484.0 1685.9 27.4 82.2 29.4 50.4 103.0 29.0 130.7 385.3 198.2 TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 39012.3;tongue: 16773.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1066.2;Peritubular cells: 2072.1;Sertoli cells: 2222.0;Smooth muscle cells: 2341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 812 "plasmacytoid DC: 398.6" "Lineage enriched" "Detected in single" 920 "dendritic cells: 398.6" "Cell line enhanced" "Detected in many" "BJ: 2309.6;fHDF/TERT166: 1289.0;hTERT-RPE1: 1399.1" "HPA047089, HPA053624" Approved NA NA 140000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (5.56e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (3.34e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-3)" "unprognostic (6.56e-3)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.51e-10)" "unprognostic (1.43e-2)" "unprognostic (8.33e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-2)" 331.1 285.0 88.0 411.0 89.8 16.7 260.8 92.5 117.3 651.3 127.3 3498.4 217.7 1928.1 201.9 1018.0 849.7 442.4 788.5 84.8 81.1 144.0 41.0 283.1 62.2 86.1 79.2 388.4 73.7 24.1 82.6 142.3 80.5 1219.0 238.0 8.0 393.6 1988.7 39012.3 148.5 636.2 2340.8 78.6 140.1 1252.6 82.9 83.3 26.3 138.9 16773.7 21.2 1630.1 454.9 79.8 375.4 291.2 213.9 33.6 335.4 893.3 129.3 2309.6 934.4 983.0 667.9 12.2 24.2 0.4 213.0 1289.0 144.6 9.2 3.7 291.2 457.0 716.2 10.8 9.1 1054.1 11.8 540.2 2.3 102.7 1067.7 44.9 738.8 0.4 1399.1 235.7 25.3 5.6 0.8 1052.1 15.3 2.7 29.1 269.6 1.5 17.0 18.5 391.5 3.0 31.1 7.2 3.8 13.3 470.0 7.9 18.2 273.8 6.8 27.7 30.0 16.5 585.7 11.6 730.6 0.6 2.7 2.9 34.0 6.5 29.2 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.4 0.2 0.0 398.6 0.0 2.1 88.0 89.8 92.5 117.3 84.8 81.1 86.1 79.2 80.5 78.6 83.3 79.8 110.0 3.2 4.1 10.4 5.9 57.1 81.2 274.1 24.5 0.8 29.9 1066.2 619.5 4.3 42.1 7.3 0.0 12.1 116.7 1.4 0.0 21.4 4.3 20.3 488.3 80.3 2.4 4.0 2.5 5.7 104.8 332.6 99.4 18.7 2.5 142.0 181.3 1.4 32.4 1.7 4.6 1.9 48.8 3.1 77.9 32.4 283.0 24.2 67.6 9.4 6.5 11.7 1.0 3.0 0.4 8.4 0.1 2072.1 2.9 169.8 0.4 1.3 23.5 0.9 2222.0 594.8 2341.4 2.5 27.3 6.7 42.8 14.6 16.0 106.7 2.8 28.7 TPPP "p25, p25alpha, TPPP/p25, TPPP1" ENSG00000171368 "Tubulin polymerization promoting protein" O94811 5 659862-693352 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 185.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Excitatory neurons: 45.2;Horizontal cells: 42.1;Inhibitory neurons: 32.6;Oligodendrocytes: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.4;AN3-CA: 5.4;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036575, HPA036576" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Mitochondria, Cytosol" "HPA036575: AB_10673501, HPA036576: AB_2675200" "unprognostic (3.66e-2)" "unprognostic (3.70e-3)" "unprognostic (9.98e-3)" "unprognostic (7.82e-2)" "unprognostic (2.05e-2)" "unprognostic (3.20e-2)" "unprognostic (2.12e-1)" "unprognostic (3.80e-3)" "unprognostic (3.85e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-3)" "unprognostic (5.48e-2)" "prognostic favorable (5.40e-6)" "unprognostic (4.03e-2)" "unprognostic (2.30e-1)" "unprognostic (2.03e-2)" "unprognostic (3.31e-2)" 3.8 6.6 100.8 0.7 136.7 0.2 2.5 55.3 120.4 1.8 0.0 12.8 5.2 3.3 0.5 11.0 10.4 1.7 9.8 112.3 69.9 4.4 2.7 10.2 0.3 110.3 102.3 1.8 6.0 2.1 19.5 2.2 107.7 2.3 1.8 6.3 5.7 3.6 10.5 8.2 9.5 3.6 47.5 2.6 4.9 2.2 124.6 0.4 6.9 5.3 1.4 6.8 2.7 185.2 0.2 7.4 0.3 5.4 0.8 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.5 0.0 1.9 2.9 2.9 0.0 0.0 1.5 2.5 0.2 3.6 0.2 0.8 0.2 0.3 0.0 0.7 0.0 0.1 0.2 0.0 0.1 0.1 2.7 0.0 0.2 0.2 0.5 0.2 0.8 0.7 0.3 0.1 1.0 0.2 1.0 13.2 1.6 0.8 0.3 3.6 0.3 0.7 0.2 0.1 0.2 2.7 0.0 0.2 1.0 0.2 0.0 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 100.8 136.7 55.3 120.4 112.3 69.9 110.3 102.3 107.7 47.5 124.6 185.2 1.6 38.5 10.0 6.8 0.7 4.1 1.4 0.6 9.6 21.3 3.1 2.4 18.4 2.8 5.3 1.8 0.0 0.0 1.1 5.7 1.9 2.4 9.1 26.6 0.9 2.0 10.2 0.0 45.2 0.7 0.3 3.3 3.1 5.8 4.5 0.1 2.2 4.3 3.3 42.1 32.6 6.5 0.0 0.0 2.2 7.2 0.3 1.2 1.8 4.7 0.1 0.9 0.0 6.6 104.7 0.7 5.2 0.4 3.3 0.8 10.3 1.1 13.5 2.4 0.0 1.5 4.2 2.2 0.8 6.7 3.1 0.0 4.8 0.1 4.8 4.1 TPPP2 "C14orf8, CT152, p18, p25beta" ENSG00000179636 "Tubulin polymerization promoting protein family member 2" P59282 14 21024109-21036276 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 254.8" "Cell type enriched" "Detected in some" 4 "Late spermatids: 9161.6" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA004120 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA004120: AB_2303582" "unprognostic (2.91e-2)" "unprognostic (2.49e-3)" "unprognostic (2.54e-1)" "unprognostic (1.66e-2)" "unprognostic (2.14e-2)" "unprognostic (2.57e-3)" "unprognostic (4.63e-4)" "unprognostic (3.83e-1)" "unprognostic (3.16e-1)" "unprognostic (1.09e-1)" "unprognostic (4.64e-4)" "unprognostic (2.51e-4)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.21e-1)" 0.1 0.4 0.8 0.1 0.9 0.0 0.5 0.8 1.1 0.2 1.3 0.1 0.1 0.2 3.4 0.0 0.2 0.3 0.6 0.8 0.8 0.9 13.3 0.1 0.0 0.9 0.8 0.8 0.2 0.2 0.1 0.0 0.9 0.4 0.3 0.3 1.4 0.2 3.2 0.1 0.3 0.0 0.9 0.1 0.1 254.8 0.9 0.0 0.1 4.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.8 1.1 0.8 0.8 0.9 0.8 0.9 0.9 0.9 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.1 1897.4 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9161.6 47.5 2.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 52.0 30.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;pancreas: 91.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 177.7;Proximal enterocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 61.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 23.6" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA020899: AB_1845835, HPA076667: " "unprognostic (5.41e-2)" "prognostic favorable (2.13e-4)" "unprognostic (2.94e-1)" "unprognostic (9.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (3.59e-3)" "unprognostic (8.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.89e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.16e-9)" "unprognostic (1.96e-3)" "unprognostic (6.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" 3.7 5.1 24.3 4.4 37.8 2.7 4.8 29.9 33.1 5.2 15.1 25.4 22.0 4.7 0.9 20.5 5.1 3.2 10.7 23.5 23.7 19.1 24.3 8.1 2.4 33.1 32.4 6.4 91.4 2.5 6.0 3.3 28.2 8.0 6.9 1.7 11.8 3.4 6.2 15.6 26.0 1.5 20.8 5.0 29.3 9.3 31.9 2.0 5.5 3.1 1.5 7.8 6.9 56.4 10.2 11.4 3.8 17.0 5.2 5.5 30.1 7.0 4.3 7.0 3.9 38.5 12.1 18.6 10.1 3.6 9.2 30.4 7.9 3.9 0.9 11.9 11.1 8.7 17.5 25.5 7.9 13.5 10.8 4.7 7.5 6.2 4.3 4.6 4.5 8.2 16.1 6.4 2.1 61.9 8.9 29.0 13.5 55.5 14.8 26.3 9.1 28.4 15.9 21.0 24.4 8.9 10.8 49.6 13.0 2.9 57.8 21.0 5.0 12.7 6.0 20.1 15.1 5.3 11.0 9.7 9.1 12.1 7.2 0.0 0.8 0.0 0.3 0.8 0.1 0.3 0.3 0.5 0.6 0.3 0.1 0.3 0.0 0.8 0.4 0.6 0.6 0.2 24.3 37.8 29.9 33.1 23.5 23.7 33.1 32.4 28.2 20.8 31.9 56.4 4.6 19.2 5.5 6.2 3.5 1.8 1.3 2.6 2.2 19.3 13.2 9.5 7.6 15.7 2.6 16.5 6.2 5.4 8.4 177.7 7.9 8.0 3.1 7.6 4.1 2.9 9.0 7.4 3.3 45.4 1.3 3.0 15.3 9.6 1.3 8.7 3.9 19.5 3.6 11.8 3.8 46.0 6.1 2.8 1.6 5.3 3.4 5.2 5.4 1.0 2.8 12.4 1.0 2.5 30.4 15.3 39.7 4.5 1.9 3.3 95.9 20.0 2.3 7.3 6.6 3.2 4.5 2.7 4.4 5.8 2.8 1.9 4.5 10.3 36.7 1.7 TRAK1 "KIAA1042, MILT1, OIP106" ENSG00000182606 "Trafficking kinesin protein 1" Q9UPV9 3 42013802-42225890 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 168.9;skeletal muscle: 262.4;tongue: 202.6" "Cell type enhanced" "Detected in all" "Astrocytes: 173.0;Cardiomyocytes: 262.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RT4: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005853, HPA011367" Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" Nucleoplasm "HPA005853: AB_1854778, HPA011367: AB_2668495" "unprognostic (5.55e-2)" "unprognostic (1.38e-2)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.56e-3)" "prognostic favorable (4.84e-8)" "unprognostic (3.65e-2)" "unprognostic (1.70e-1)" "unprognostic (1.00e-2)" "unprognostic (4.61e-3)" 26.0 13.1 23.0 17.1 26.2 18.2 18.0 28.5 27.7 13.7 27.8 27.1 34.5 12.2 10.4 29.3 19.8 26.9 168.9 24.2 19.5 20.1 15.3 24.1 22.8 24.4 30.3 8.5 13.1 32.2 17.7 15.3 21.6 15.4 25.4 96.7 44.1 13.1 262.4 45.1 42.0 16.8 19.1 22.2 61.0 12.1 26.0 17.9 31.4 202.6 22.6 33.8 18.4 21.4 22.2 19.2 37.9 16.4 25.6 24.9 48.9 29.5 33.5 19.0 20.6 12.8 30.7 43.9 15.1 75.2 20.4 10.7 26.5 68.8 20.6 39.6 18.8 30.4 19.9 35.6 12.8 34.6 22.9 21.4 28.9 41.9 38.0 28.1 38.6 11.6 15.7 34.4 24.4 9.2 3.7 18.1 16.4 60.4 14.8 16.1 14.1 36.8 26.3 165.3 23.8 27.9 11.3 16.3 16.2 31.4 14.6 29.3 39.6 16.6 19.2 99.0 17.4 25.7 23.0 38.9 18.2 30.2 16.4 0.9 1.3 0.5 0.6 2.4 0.5 2.4 0.9 0.7 1.5 3.6 0.3 0.9 0.6 1.0 1.4 2.5 0.4 0.7 23.0 26.2 28.5 27.7 24.2 19.5 24.4 30.3 21.6 19.1 26.0 21.4 27.4 32.1 32.4 173.0 23.9 38.0 16.3 32.1 30.1 22.7 18.5 17.7 262.0 24.3 38.1 14.7 100.1 23.0 13.9 61.4 1.9 10.8 1.1 53.3 21.8 23.9 22.8 6.5 62.0 12.3 18.3 14.0 81.1 70.0 10.8 11.5 6.8 10.3 15.7 33.7 81.3 39.5 26.4 15.7 33.4 3.0 1.8 23.3 24.9 97.4 17.9 27.8 4.1 105.1 64.8 24.2 37.1 2.6 5.4 18.5 97.9 10.2 80.6 139.9 32.9 15.9 29.9 1.0 3.9 27.5 43.2 15.7 7.5 4.6 35.6 27.0 TRDN TRISK ENSG00000186439 Triadin Q13061 6 123216339-123637093 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 421.6;skeletal muscle: 1944.1;tongue: 1018.2" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 1145.1;Muller glia cells: 765.7;Skeletal myocytes: 398.6" "Group enriched" "Detected in some" 5 "head and neck cancer: 2.2;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.9" "Region enriched" "Detected in some" 10 "olfactory bulb: 11.0" "Region enriched" "Detected in some" 23 "olfactory bulb: 28.9" "HPA038226, HPA058226" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA038226: AB_10795574, HPA058226: AB_2683643" "unprognostic (1.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.20e-2)" "unprognostic (3.06e-3)" "unprognostic (2.40e-1)" "unprognostic (2.38e-1)" "unprognostic (2.42e-1)" "unprognostic (8.42e-2)" "unprognostic (8.71e-2)" "unprognostic (9.93e-3)" "unprognostic (2.12e-1)" "unprognostic (2.55e-2)" "unprognostic (3.97e-2)" 16.3 2.6 4.2 0.0 3.7 0.0 2.0 4.0 5.8 0.7 3.1 0.4 0.0 1.7 10.4 18.5 12.5 0.2 421.6 3.0 12.5 0.4 0.1 0.4 0.1 6.7 7.0 1.3 0.1 0.0 15.3 0.2 7.9 17.0 0.3 83.5 13.1 0.9 1944.1 0.6 0.2 1.0 9.2 0.1 0.1 5.1 10.2 0.3 0.3 1018.2 0.1 0.0 0.6 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.7 4.0 5.8 3.0 12.5 6.7 7.0 7.9 9.2 10.2 6.3 0.3 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 7.9 0.0 0.3 1145.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 68.0 0.0 0.0 6.0 0.0 0.0 1.1 0.0 0.0 38.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.4 35.5 13.1 0.5 1.8 0.0 0.0 765.7 0.0 3.0 3.2 0.0 0.0 11.3 0.0 0.0 0.0 0.2 0.0 21.8 0.0 398.6 7.1 1.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TRIM45 "FLJ13181, RNF99" ENSG00000134253 "Tripartite motif containing 45" Q9H8W5 1 117111060-117122587 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 29.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cardiomyocytes: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030266, HPA054308" Uncertain Supported "Cytokinetic bridge,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Cytokinetic bridge" "HPA030266: AB_10795476, HPA054308: AB_2682445" "prognostic favorable (1.58e-4)" "unprognostic (2.68e-2)" "unprognostic (1.12e-2)" "unprognostic (3.49e-1)" "unprognostic (5.70e-2)" "unprognostic (9.66e-2)" "unprognostic (2.19e-3)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" "unprognostic (1.43e-2)" "unprognostic (3.05e-1)" "unprognostic (5.45e-2)" "unprognostic (7.09e-2)" "unprognostic (3.90e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.27e-2)" 2.9 7.1 3.9 1.2 3.6 2.1 5.4 2.9 3.9 7.3 3.1 6.2 3.7 8.7 6.6 2.2 10.0 2.9 12.6 3.4 3.1 6.7 1.7 2.4 0.9 3.3 3.2 9.1 11.4 5.6 10.5 2.0 3.0 10.7 2.1 3.6 4.7 5.7 29.1 5.8 3.1 4.9 3.2 3.2 5.7 7.6 3.7 0.8 12.0 10.5 0.6 8.1 5.3 3.8 4.3 3.6 16.0 7.5 1.3 3.6 11.9 4.8 2.0 3.3 3.3 1.8 3.9 0.1 3.5 2.2 3.5 3.9 3.7 3.9 4.4 2.5 3.8 2.6 13.9 2.1 2.3 2.4 3.6 4.6 3.8 5.5 3.9 6.2 4.1 4.7 3.2 3.2 3.1 19.3 1.4 2.7 8.7 2.5 3.5 6.1 31.4 0.9 4.5 3.9 11.9 3.1 3.9 3.6 3.1 15.0 6.2 3.1 1.4 4.6 6.6 2.8 4.3 8.7 3.5 0.3 6.0 2.2 12.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.5 0.0 3.9 3.6 2.9 3.9 3.4 3.1 3.3 3.2 3.0 3.2 3.7 3.8 1.1 9.6 2.7 4.9 0.1 1.1 1.8 1.5 1.2 1.4 5.0 3.4 12.2 4.3 2.2 1.8 4.2 2.7 0.1 0.3 1.9 1.9 5.7 2.8 2.6 1.5 1.8 2.5 2.5 3.2 1.2 2.1 3.6 2.8 0.0 4.0 2.2 0.2 0.8 1.7 1.9 1.6 0.0 0.3 0.3 2.7 1.8 0.4 0.0 3.7 0.0 1.4 0.0 3.5 2.3 2.1 0.0 1.9 0.6 0.5 0.4 0.4 1.9 1.4 0.0 3.1 2.1 6.1 5.3 1.3 1.6 1.1 0.4 5.5 1.6 1.3 TRIM54 "MURF, MURF-3, RNF30" ENSG00000138100 "Tripartite motif containing 54" Q9BYV2 2 27282429-27307439 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 213.2;skeletal muscle: 580.7;tongue: 177.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 81.7;Ductal cells: 35.5;Exocrine glandular cells: 42.5;Pancreatic endocrine cells: 46.5;Skeletal myocytes: 17.9;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.1" "Immune cell enriched" "Detected in single" 17 "NK-cell: 3.6" "Lineage enriched" "Detected in single" 17 "NK-cells: 3.6" "Group enriched" "Detected in some" 8 "HAP1: 7.3;NTERA-2: 15.6" "Region enhanced" "Detected in some" "amygdala: 3.1" HPA019690 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA019690: AB_1858306" "unprognostic (6.98e-3)" "unprognostic (4.56e-3)" "unprognostic (3.22e-2)" "unprognostic (2.24e-2)" "unprognostic (1.58e-3)" "unprognostic (7.49e-2)" "unprognostic (1.25e-7)" "unprognostic (3.88e-3)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.56e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.41e-2)" "unprognostic (3.19e-1)" "unprognostic (1.15e-1)" "unprognostic (6.92e-2)" 0.4 9.3 1.5 0.0 0.9 0.0 0.3 0.9 5.1 0.9 0.1 0.3 4.3 0.8 24.5 5.0 0.8 0.2 213.2 2.3 0.0 1.7 0.1 0.2 0.2 0.6 0.3 0.5 0.5 0.0 0.1 0.0 0.3 3.4 0.0 0.0 9.5 0.1 580.7 0.9 2.1 0.0 0.3 0.9 0.1 22.3 0.1 0.1 0.5 177.3 0.0 0.1 0.5 1.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.2 0.0 1.4 1.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 15.6 0.0 0.0 0.5 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 1.5 0.9 0.9 5.1 2.3 0.0 0.6 0.3 0.3 0.3 0.1 1.2 0.0 0.0 0.0 0.7 0.2 0.0 0.2 0.3 0.0 0.0 0.5 0.4 81.7 10.0 0.1 3.7 0.0 0.0 0.3 2.3 0.0 35.5 1.5 0.1 0.0 0.8 0.0 2.7 11.3 42.5 0.0 2.2 0.0 0.2 4.5 0.0 0.4 0.0 0.1 0.0 0.8 1.8 0.0 0.0 0.0 4.7 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.3 46.5 1.9 0.7 0.0 0.2 2.4 3.1 0.2 0.0 0.0 17.9 16.8 6.8 2.4 0.0 0.0 0.0 0.3 0.2 6.4 0.3 TRPT1 MGC11134 ENSG00000149743 "TRNA phosphotransferase 1" Q86TN4 11 64223799-64226254 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 173.8" "Cell type enhanced" "Detected in many" "Early spermatids: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038705, HPA038706" Uncertain Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 27: Mucus-secreting cells - Mucin production" Mitochondria "HPA038705: AB_2676161, HPA038706: AB_10671863" "unprognostic (2.50e-2)" "unprognostic (1.72e-1)" "unprognostic (1.33e-1)" "unprognostic (3.59e-2)" "unprognostic (7.20e-2)" "unprognostic (1.53e-1)" "unprognostic (5.84e-2)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-3)" "unprognostic (1.12e-1)" "unprognostic (7.71e-2)" "unprognostic (7.38e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-1)" "unprognostic (1.99e-1)" "unprognostic (4.58e-3)" 27.6 38.8 33.1 14.1 34.9 8.4 27.5 36.3 36.2 26.3 33.8 35.2 22.2 23.1 21.4 35.2 26.3 15.4 88.3 31.7 34.6 52.0 46.5 20.3 16.3 35.0 34.0 26.0 51.3 19.2 35.2 10.9 33.7 36.0 18.4 12.7 38.9 28.4 173.8 27.4 30.3 12.0 34.1 30.8 41.9 51.1 36.7 21.1 33.5 116.1 17.6 30.0 25.8 34.3 25.1 24.5 26.5 43.0 32.0 23.5 32.2 16.4 31.6 28.7 24.0 16.1 37.1 24.7 63.6 27.4 22.2 34.1 11.8 35.7 10.1 23.8 14.2 12.7 23.8 28.0 46.4 16.2 21.4 17.7 20.7 31.6 28.1 52.7 20.4 49.0 22.3 27.1 24.2 59.4 30.3 33.7 16.8 33.3 26.1 39.3 19.5 71.4 74.4 29.1 23.0 33.4 13.2 32.1 47.5 18.0 37.1 25.8 23.9 19.4 14.9 37.9 16.4 53.0 14.3 16.3 46.7 8.3 32.1 11.0 16.9 28.5 18.8 31.2 15.0 38.0 18.5 19.9 24.4 39.9 20.1 23.3 15.8 26.1 27.4 59.0 25.2 12.0 33.1 34.9 36.3 36.2 31.7 34.6 35.0 34.0 33.7 34.1 36.7 34.3 17.1 9.6 23.1 9.8 31.4 13.3 18.7 32.7 28.5 8.9 40.4 45.3 42.5 32.9 25.5 27.6 0.0 44.4 17.0 66.3 95.9 41.4 147.5 41.3 20.1 17.5 26.9 14.9 2.8 58.4 46.7 19.8 41.8 27.5 24.6 10.0 21.0 30.0 25.5 10.1 4.9 111.3 30.5 18.9 12.8 82.1 19.9 15.0 37.4 2.8 27.2 32.1 15.5 7.5 6.8 46.6 60.5 17.0 47.1 24.0 92.0 82.9 48.2 11.6 6.6 22.4 29.3 59.6 13.4 42.8 18.5 36.0 21.8 20.2 40.3 22.6 TRUB2 CLONE24922 ENSG00000167112 "TruB pseudouridine synthase family member 2" O95900 9 128305159-128322447 "Predicted intracellular proteins" "mRNA processing" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021211 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA021211: AB_1858375" "unprognostic (2.40e-1)" "unprognostic (2.02e-2)" "unprognostic (1.31e-1)" "unprognostic (3.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (4.52e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (3.04e-2)" "unprognostic (4.81e-3)" "prognostic favorable (5.57e-10)" "unprognostic (8.74e-3)" "unprognostic (8.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" 3.7 8.5 8.7 3.6 9.0 4.2 4.7 8.9 9.3 3.3 8.7 4.5 5.0 3.3 2.9 6.3 4.1 2.7 8.7 8.5 8.1 6.5 12.9 2.4 4.5 9.3 9.3 3.8 5.2 7.2 6.8 2.7 9.8 3.6 4.2 3.6 4.8 3.4 7.2 5.4 4.3 3.2 7.7 3.6 4.6 3.1 9.5 3.5 4.7 9.8 4.3 4.0 3.5 9.9 6.6 14.9 6.7 9.2 10.7 7.9 7.1 7.1 8.5 11.6 9.5 11.1 8.3 14.7 6.0 9.7 11.0 17.5 15.4 12.4 7.8 7.1 10.2 6.9 12.8 10.4 8.2 12.7 8.9 10.0 13.7 11.4 10.7 7.2 12.0 12.8 26.2 6.4 9.3 19.7 17.1 14.7 9.2 22.2 19.0 13.3 10.9 21.0 10.7 5.9 14.4 10.6 13.2 14.6 9.5 5.2 19.1 8.7 8.1 9.4 7.5 11.2 8.6 7.5 16.4 11.9 9.9 9.9 10.5 3.6 3.6 1.1 5.0 3.8 5.7 6.3 4.8 5.7 5.5 5.3 5.5 5.7 1.8 6.5 2.0 3.8 6.2 3.8 8.7 9.0 8.9 9.3 8.5 8.1 9.3 9.3 9.8 7.7 9.5 9.9 10.9 25.6 10.3 1.6 17.1 9.6 13.7 43.0 15.4 21.3 14.6 15.7 49.9 24.3 27.0 35.0 16.7 51.6 10.9 19.8 64.6 39.0 12.9 15.1 20.7 16.4 19.1 16.2 5.0 35.4 45.9 15.4 27.0 15.9 8.2 22.0 17.2 50.7 31.0 3.3 5.2 26.4 34.6 9.0 4.1 16.4 20.8 12.4 12.4 3.7 16.8 15.4 18.6 3.0 10.5 27.2 19.1 18.0 17.8 14.9 34.0 78.6 16.9 16.7 0.0 17.2 16.3 15.8 19.2 22.1 10.5 28.0 13.9 46.1 35.3 11.1 TSPAN32 "PHEMX, TSSC6" ENSG00000064201 "Tetraspanin 32" Q96QS1 11 2301997-2318204 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 19.9;heart muscle: 11.4;lymphoid tissue: 5.5" "Cell type enhanced" "Detected in some" "dendritic cells: 44.6;Erythroid cells: 20.6;granulocytes: 30.4;Langerhans cells: 19.6;NK-cells: 87.6;T-cells: 21.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "HEL: 15.0;HL-60: 6.6;NB-4: 5.3;THP-1: 5.6;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA024135 Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA024135: AB_1858409" "unprognostic (7.50e-3)" "unprognostic (4.88e-4)" "unprognostic (1.58e-2)" "unprognostic (1.74e-1)" "unprognostic (4.45e-3)" "unprognostic (2.10e-4)" "unprognostic (7.72e-3)" "unprognostic (8.25e-3)" "unprognostic (9.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.28e-7)" "unprognostic (1.07e-1)" "unprognostic (4.20e-1)" "unprognostic (4.35e-1)" "unprognostic (8.13e-2)" 0.5 0.5 0.2 1.6 0.2 19.9 0.3 0.5 0.2 1.1 0.0 0.5 0.3 0.7 0.2 0.4 0.5 1.4 11.4 0.2 0.3 0.2 0.4 2.0 5.5 0.5 0.3 0.5 0.0 0.0 0.0 0.3 0.3 0.2 0.3 0.2 0.9 0.5 0.3 0.6 0.5 0.0 0.1 3.5 0.9 0.2 0.2 0.9 0.2 0.2 2.4 0.7 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 15.0 0.0 0.1 0.6 6.6 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 8.9 0.0 40.5 31.8 4.2 25.8 40.9 16.5 2.4 9.1 22.7 32.2 1.1 7.2 27.1 17.3 58.6 46.0 1.6 13.2 21.7 0.2 0.2 0.5 0.2 0.2 0.3 0.5 0.3 0.3 0.1 0.2 0.5 0.5 0.0 6.7 0.0 4.5 0.9 0.0 0.0 0.0 0.0 0.2 0.1 15.9 0.0 0.6 0.0 0.0 0.1 44.6 0.0 0.0 0.0 0.8 0.1 0.3 0.8 0.0 20.6 0.0 0.0 0.3 1.3 0.5 0.0 30.4 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 6.5 19.6 4.1 0.9 13.6 1.8 1.0 14.4 0.2 87.6 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.2 1.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 21.9 0.0 0.0 0.1 TSPOAP1 "BZRAP1, KIAA0612, PRAX-1, RIM-BP1, RIMBP1" ENSG00000005379 "TSPO associated protein 1" O95153 17 58301228-58328795 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 9.0;Breast glandular cells: 7.1;Breast myoepithelial cells: 8.1;Collecting duct cells: 7.3;dendritic cells: 22.3;Endometrial ciliated cells: 9.3;Respiratory ciliated cells: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 127.5;HL-60: 52.6;NB-4: 52.6;REH: 99.9;THP-1: 33.0;U-266/70: 36.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024662, HPA025244" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA024662: AB_2066340, HPA025244: AB_1845509" "unprognostic (2.03e-2)" "unprognostic (5.32e-2)" "unprognostic (4.60e-2)" "unprognostic (2.23e-1)" "unprognostic (2.24e-1)" "unprognostic (8.23e-4)" "unprognostic (1.24e-1)" "unprognostic (3.03e-3)" "unprognostic (1.03e-1)" "unprognostic (1.05e-1)" "prognostic favorable (9.15e-7)" "unprognostic (1.62e-1)" "unprognostic (7.44e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (3.82e-2)" "unprognostic (1.22e-2)" 9.7 28.6 71.0 5.6 66.2 40.6 18.4 45.1 92.0 47.3 45.7 35.7 4.0 38.4 6.5 11.0 62.5 5.8 18.1 68.9 47.9 36.6 16.6 18.0 10.8 45.0 49.0 65.9 33.2 14.4 69.9 1.7 44.8 49.1 3.5 17.9 27.7 16.2 8.9 11.8 19.1 6.3 40.2 25.3 26.4 3.7 56.9 13.2 44.9 3.2 5.0 25.0 22.6 52.8 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.4 0.2 0.2 0.0 0.8 0.0 2.8 2.6 0.5 0.0 0.4 0.0 0.0 0.1 127.5 1.1 0.7 1.7 0.0 0.2 52.6 5.1 0.0 0.6 0.0 0.0 12.5 0.0 17.8 2.0 9.3 0.0 0.0 18.1 52.6 0.8 0.0 0.1 99.9 0.0 13.7 0.3 0.1 7.2 4.9 0.2 0.2 0.0 0.1 0.2 33.0 0.0 0.0 1.1 0.2 0.1 36.4 7.2 9.5 0.1 1.6 0.0 0.2 0.0 0.0 1.7 0.0 0.7 0.0 0.1 0.4 0.0 0.0 0.1 0.4 0.0 0.8 0.0 0.0 0.0 0.3 71.0 66.2 45.1 92.0 68.9 47.9 45.0 49.0 44.8 40.2 56.9 52.8 0.6 9.6 9.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 7.1 8.1 0.0 0.0 4.3 7.3 0.0 0.0 22.3 0.0 1.9 0.9 0.0 9.3 3.1 0.2 0.0 0.0 0.0 0.2 0.7 1.0 0.0 3.7 1.3 4.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.8 8.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 4.0 0.1 0.0 0.0 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TTC1 TPR1 ENSG00000113312 "Tetratricopeptide repeat domain 1" Q99614 5 160009113-160065543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036557, HPA057502" Approved Enhanced Cytosol NA NA 17000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA036557: AB_10670112, HPA057502: AB_2683450" "unprognostic (4.34e-3)" "unprognostic (2.26e-2)" "unprognostic (3.05e-2)" "unprognostic (7.38e-2)" "unprognostic (6.62e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.29e-2)" "unprognostic (2.38e-1)" "unprognostic (5.50e-2)" "unprognostic (2.31e-1)" "unprognostic (2.35e-1)" "unprognostic (1.08e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (4.05e-2)" "unprognostic (6.16e-2)" 37.0 46.5 77.6 35.6 79.7 26.2 39.4 84.2 111.7 31.5 71.2 44.5 27.3 32.2 58.1 37.4 32.2 26.2 59.9 79.4 83.1 49.5 45.5 33.0 47.8 90.6 85.4 32.6 27.4 45.1 29.8 35.5 88.7 33.4 45.4 42.9 39.4 37.2 91.2 34.8 30.9 41.8 80.3 36.6 34.6 33.8 83.8 48.7 35.7 77.0 55.9 35.7 27.6 84.1 83.2 85.1 62.2 104.4 71.9 51.6 70.5 90.8 80.4 97.7 115.6 120.2 94.0 84.5 172.7 78.2 132.9 63.9 83.5 124.7 156.6 157.7 88.4 75.9 63.0 87.3 102.0 127.2 61.2 48.7 81.0 86.5 71.8 71.8 118.8 74.2 73.6 81.7 112.3 65.0 92.8 99.8 70.7 67.3 85.8 88.4 87.0 93.6 124.2 76.8 51.2 57.7 63.1 74.4 175.1 58.3 117.6 121.5 84.4 64.8 55.8 58.5 141.9 58.4 114.8 82.3 89.6 143.3 85.9 109.8 72.8 105.7 57.6 80.9 73.4 92.6 68.3 68.0 73.5 86.0 62.5 69.1 103.0 87.7 80.6 65.4 90.2 113.1 77.6 79.7 84.2 111.7 79.4 83.1 90.6 85.4 88.7 80.3 83.8 84.1 48.6 67.3 50.8 20.9 55.0 47.0 33.6 89.2 28.5 38.4 40.4 47.0 237.0 40.0 67.4 46.0 20.9 108.7 36.0 58.0 162.4 114.2 115.3 62.8 46.5 61.3 35.3 89.2 54.0 106.5 77.9 57.4 23.4 54.8 83.4 41.3 52.1 72.8 90.0 35.3 47.6 51.4 83.4 48.1 34.7 39.9 46.9 52.4 28.4 23.4 70.1 99.1 68.0 43.7 57.0 98.5 54.7 63.9 42.9 37.6 53.7 144.9 89.4 50.2 59.2 55.7 59.2 142.9 101.5 37.8 47.3 99.9 50.8 53.6 53.7 21.9 TTC36 HBP21 ENSG00000172425 "Tetratricopeptide repeat domain 36" A6NLP5 11 118527472-118531197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 171.5" "Group enriched" "Detected in many" 13 "Hepatocytes: 492.9;Proximal enterocytes: 185.5;Proximal tubular cells: 172.9" "Group enriched" "Detected in some" 7 "breast cancer: 5.0;liver cancer: 12.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "SK-BR-3: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038731 Enhanced Uncertain Nucleoplasm NA NA 100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA038731: AB_10672651" "unprognostic (1.57e-3)" "unprognostic (2.58e-3)" "unprognostic (1.16e-1)" "unprognostic (6.50e-2)" "unprognostic (1.02e-2)" "unprognostic (2.17e-1)" "prognostic favorable (1.81e-5)" "unprognostic (6.32e-2)" "unprognostic (8.80e-2)" "unprognostic (6.14e-2)" "unprognostic (4.77e-3)" "unprognostic (3.38e-2)" "unprognostic (5.77e-7)" "unprognostic (5.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (8.95e-3)" 8.0 1.3 0.8 0.1 0.8 0.0 11.1 0.8 0.7 0.3 0.7 0.5 5.9 0.4 18.5 0.5 0.5 0.1 1.0 0.3 0.6 8.9 171.5 0.3 0.1 1.1 0.7 0.6 1.2 0.0 1.6 0.1 0.6 1.0 0.0 0.3 0.9 0.0 1.4 0.5 4.1 0.0 0.6 0.2 0.7 0.8 0.6 0.0 0.7 0.4 0.0 0.5 0.3 1.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.2 0.7 0.0 0.0 0.2 0.0 0.0 9.7 0.0 0.0 0.8 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.8 0.8 0.7 0.3 0.6 1.1 0.7 0.6 0.6 0.6 1.0 0.3 0.0 0.0 0.3 2.4 0.3 0.6 0.2 0.6 0.1 21.2 11.3 0.3 11.5 0.1 12.9 0.0 1.5 0.1 0.8 17.6 0.2 0.1 1.2 0.6 1.1 2.4 16.4 0.2 0.5 0.2 0.3 2.0 1.7 0.0 0.4 9.7 492.9 0.1 0.0 0.3 9.3 0.0 14.2 0.3 0.2 0.3 0.9 0.0 0.0 0.6 1.1 0.0 0.0 0.1 0.2 7.6 0.0 0.3 1.9 185.5 172.9 0.2 0.8 0.0 0.2 0.2 0.3 0.3 0.3 0.1 2.1 1.1 0.4 11.7 1.3 TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 59.5" "Group enriched" "Detected in many" 9 "Early spermatids: 425.0;Late spermatids: 616.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 31.7" "Lineage enriched" "Detected in single" 42 "dendritic cells: 31.7" "Cell line enhanced" "Detected in many" "HDLM-2: 70.6;MCF7: 52.4;SK-BR-3: 153.7;T-47d: 111.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 2.2 8.2 3.5 3.3 3.5 1.7 35.9 3.0 9.6 14.1 0.0 29.5 6.1 1.0 15.9 18.4 7.5 14.9 15.3 1.0 11.4 26.6 2.8 9.1 1.4 7.4 5.3 0.3 13.5 13.5 11.0 0.3 14.0 20.5 35.2 4.6 11.5 4.2 4.1 10.5 8.1 1.6 2.2 0.3 29.4 59.5 7.7 0.5 10.1 1.7 2.0 8.0 9.4 3.7 6.4 3.4 0.7 0.3 0.4 0.7 28.2 0.3 0.2 0.2 0.2 18.2 2.8 0.1 9.6 0.4 0.4 0.2 3.8 0.2 0.1 70.6 9.7 0.5 1.8 3.2 1.1 0.0 0.7 0.1 1.6 0.1 0.0 0.8 1.4 0.2 0.4 0.1 0.2 52.4 0.6 0.2 4.8 33.8 0.6 0.1 0.2 4.3 28.6 9.1 22.1 1.6 0.5 153.7 1.8 2.0 111.7 0.8 0.8 0.4 2.5 0.5 0.5 5.4 7.1 0.2 2.1 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 31.7 0.0 0.3 3.5 3.5 3.0 9.6 1.0 11.4 7.4 5.3 14.0 2.2 7.7 3.7 0.4 3.2 25.2 1.3 1.1 1.5 5.3 1.7 0.0 2.5 30.8 15.1 13.0 5.7 6.4 9.2 0.0 0.5 15.3 29.3 11.7 38.9 425.0 5.4 3.0 1.9 41.4 9.7 9.7 52.7 4.8 0.9 21.9 9.5 3.8 0.5 0.4 0.6 2.0 0.0 10.2 56.0 6.1 0.3 1.3 616.8 2.5 0.9 0.0 1.0 2.6 1.7 0.0 0.0 0.9 30.5 13.7 2.6 0.4 12.0 2.7 24.4 9.3 7.3 6.6 1.8 1.3 22.8 6.5 4.8 6.5 3.4 1.7 0.5 20.7 14.6 TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 167.2;skeletal muscle: 920.6;tongue: 369.5" "Cell type enriched" "Detected in many" 16 "Cardiomyocytes: 24394.9" "Cancer enriched" "Detected in single" 4 "head and neck cancer: 1.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "RH-30: 1.9" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced NA NA 16000000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB022682: , HPA007042: AB_1080292, HPA030048: AB_2732451" "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" 0.6 0.4 2.7 0.5 2.4 4.3 0.5 2.8 4.9 0.3 0.0 0.4 0.4 0.4 0.2 2.7 0.3 0.7 167.2 1.9 3.4 0.2 0.3 1.2 1.4 11.2 4.4 0.7 1.7 0.0 0.8 0.5 6.6 2.7 0.0 1.9 7.0 0.0 920.6 0.8 0.6 0.0 3.2 0.7 0.4 1.6 4.8 0.7 0.6 369.5 0.4 0.2 0.3 5.3 0.3 0.1 0.7 0.4 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.7 0.1 1.0 0.2 0.0 0.7 0.7 0.0 0.0 0.0 1.0 0.8 1.5 1.3 0.4 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.7 0.6 0.7 0.9 0.5 0.1 0.2 0.7 1.0 0.2 0.1 0.7 0.5 1.9 0.6 0.0 0.2 0.4 0.7 0.1 0.5 0.0 0.6 0.3 1.0 0.7 0.0 0.0 0.3 0.2 1.4 0.2 1.4 0.0 0.5 0.3 1.8 0.2 0.5 0.4 0.2 0.1 6.1 0.9 0.7 0.1 5.7 2.0 2.6 1.0 3.6 0.2 0.2 6.0 0.1 2.7 2.4 2.8 4.9 1.9 3.4 11.2 4.4 6.6 3.2 4.8 5.3 10.9 16.0 173.4 43.8 32.1 0.9 1.6 0.0 2.8 102.7 1.7 0.5 24394.9 30.0 6.2 0.0 20.9 0.7 6.8 0.1 1.9 14.1 43.2 3.4 6.8 99.1 4.2 3.0 25.1 28.3 0.3 502.5 3.6 7.2 10.1 0.7 2.5 0.6 0.3 16.8 31.3 0.1 0.0 0.8 0.8 6.4 1.2 26.2 0.0 25.3 0.6 12.0 2.1 11.6 4.9 0.5 0.1 4.5 10.6 0.2 0.3 0.4 2.9 27.8 0.0 1466.9 104.7 9.3 1.5 2.3 0.1 0.4 24.3 2.8 0.5 0.1 TTYH2 C17orf29 ENSG00000141540 "Tweety family member 2" Q9BSA4 17 74213571-74262020 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 214.5" "Cell type enhanced" "Detected in many" "Astrocytes: 46.0;Bipolar cells: 59.2;Langerhans cells: 52.1;Oligodendrocytes: 206.9" "Group enriched" "Detected in all" 6 "glioma: 16.7;melanoma: 20.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 13.3;intermediate monocyte: 22.3;myeloid DC: 14.6;non-classical monocyte: 28.6;plasmacytoid DC: 18.2" "Group enriched" "Detected in many" 5 "dendritic cells: 18.2;monocytes: 28.6" "Cell line enhanced" "Detected in many" "HSkMC: 22.2;SK-MEL-30: 81.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.19e-1)" "unprognostic (5.08e-1)" "unprognostic (1.58e-3)" "unprognostic (3.51e-4)" "unprognostic (1.59e-1)" "unprognostic (2.44e-1)" "unprognostic (1.67e-2)" "unprognostic (5.90e-2)" "unprognostic (8.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.81e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.74e-5)" "unprognostic (8.98e-3)" "unprognostic (5.70e-3)" "unprognostic (2.50e-3)" "unprognostic (3.51e-3)" 5.5 4.7 75.4 7.3 132.2 3.3 4.4 101.4 103.2 7.1 34.7 8.2 2.6 4.9 3.5 3.2 6.3 5.1 18.1 83.7 91.3 2.0 1.6 5.5 7.7 129.0 115.2 17.2 8.3 4.0 7.0 10.3 123.3 4.6 2.5 19.8 6.9 4.0 14.8 5.2 4.8 3.9 88.2 11.7 3.9 15.2 113.6 5.1 10.1 9.4 5.7 5.3 4.7 214.5 0.2 1.9 9.0 8.7 1.1 1.3 0.2 0.5 0.1 0.5 0.1 5.9 0.1 5.3 1.3 0.2 1.0 14.5 8.9 0.3 0.3 12.5 5.0 5.7 0.3 0.5 6.2 0.6 3.8 22.2 4.6 0.1 1.6 0.6 0.3 3.8 1.0 2.6 0.2 1.0 2.7 0.4 1.7 8.7 15.7 8.8 16.1 10.1 0.2 0.7 3.1 11.0 0.0 5.5 81.3 4.6 2.9 1.2 0.2 0.0 4.4 0.1 0.3 0.5 0.3 0.1 0.3 1.7 4.9 1.0 13.3 1.2 2.4 22.3 0.3 0.3 4.6 3.8 14.6 0.3 0.7 1.7 1.2 0.1 28.6 18.2 4.5 7.0 75.4 132.2 101.4 103.2 83.7 91.3 129.0 115.2 123.3 88.2 113.6 214.5 8.0 0.0 4.1 46.0 1.3 2.3 0.6 0.2 1.2 59.2 1.5 2.4 1.9 2.8 0.1 0.0 6.2 0.3 7.9 0.0 0.0 0.2 27.7 0.4 0.7 6.9 1.8 0.0 1.0 0.2 0.4 4.1 0.5 0.9 21.6 0.5 1.8 0.5 5.0 3.3 0.9 0.2 0.0 12.3 52.1 11.5 9.6 13.7 23.2 15.0 16.5 18.4 0.0 10.6 206.9 0.1 0.1 2.6 1.3 0.8 0.0 0.2 0.3 10.8 19.7 3.2 2.7 2.4 1.5 0.4 2.6 0.3 2.3 4.3 0.0 0.4 TUB rd5 ENSG00000166402 "TUB bipartite transcription factor" P50607 11 8019244-8106243 "Disease related genes, Predicted intracellular proteins" "Phagocytosis, Sensory transduction" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 79.1;retina: 82.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 41.7;Excitatory neurons: 34.6;Horizontal cells: 30.3;Inhibitory neurons: 23.2;Oligodendrocyte precursor cells: 23.1;Rod photoreceptor cells: 55.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 26.8;HEK 293: 33.7;HeLa: 54.3;SCLC-21H: 51.0;SH-SY5Y: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017997, HPA049019" Enhanced Approved "Nucleoli,Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Centriolar satellite" Nucleoli "HPA017997: AB_1858449, HPA049019: AB_2680601" "unprognostic (2.53e-1)" "unprognostic (7.23e-2)" "unprognostic (1.80e-2)" "unprognostic (4.06e-2)" "unprognostic (9.62e-2)" "unprognostic (1.47e-2)" "unprognostic (1.53e-2)" "unprognostic (2.53e-1)" "unprognostic (9.71e-2)" "unprognostic (5.08e-2)" "prognostic favorable (2.85e-4)" "unprognostic (4.18e-1)" "prognostic favorable (2.35e-5)" "unprognostic (8.37e-3)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (1.39e-2)" 7.1 17.3 25.5 2.5 26.2 0.2 6.6 14.4 25.1 26.5 2.5 8.1 2.0 24.4 10.3 3.2 19.8 4.7 12.6 35.9 31.4 11.4 0.9 3.9 1.9 18.6 79.1 18.2 4.6 13.7 31.7 4.3 30.8 8.6 2.3 82.6 5.3 8.1 2.9 6.4 3.9 11.3 18.0 1.7 3.7 5.0 27.5 2.5 10.8 8.2 0.9 11.0 13.9 16.4 0.0 9.8 14.2 16.7 13.2 4.3 0.0 9.4 2.5 9.9 13.2 0.0 0.1 0.0 0.8 13.2 4.6 0.1 26.8 2.0 9.2 0.0 33.7 0.0 54.3 6.1 2.2 0.0 0.4 6.8 2.4 4.7 0.0 0.8 0.9 15.7 0.0 0.1 4.8 1.4 0.1 0.1 9.4 0.0 0.1 12.6 0.2 0.0 0.0 0.5 51.0 38.1 6.9 0.1 2.6 6.3 1.4 0.2 0.0 5.4 12.5 0.9 3.9 0.1 0.0 0.0 4.9 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.5 26.2 14.4 25.1 35.9 31.4 18.6 79.1 30.8 18.0 27.5 16.4 0.5 0.0 0.0 15.0 0.0 0.8 2.0 0.1 1.2 15.5 0.8 1.9 3.5 1.5 0.7 0.0 41.7 0.2 0.1 0.0 5.9 0.1 4.2 4.4 14.1 0.5 1.8 0.0 34.6 0.0 0.4 6.8 0.0 0.4 1.3 10.1 1.4 0.2 0.2 30.3 23.2 0.0 0.0 0.0 0.7 4.9 14.6 0.2 1.8 8.4 0.0 12.6 0.0 23.1 1.9 0.0 0.0 14.7 0.1 1.5 0.0 10.2 5.1 55.6 0.0 6.8 1.5 1.6 1.4 0.2 0.9 0.0 0.5 0.5 0.0 0.4 TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 610000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB075730: AB_2665736, CAB075731: AB_2665737, CAB075732: AB_2665738, HPA018991: AB_1858458, HPA024087: AB_1858459" "unprognostic (1.40e-1)" "unprognostic (7.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-2)" "unprognostic (3.39e-1)" "unprognostic (1.23e-3)" "unprognostic (8.05e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.69e-6)" "unprognostic (5.26e-2)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (7.36e-2)" 69.7 114.6 69.6 67.1 74.2 75.1 65.8 78.9 78.1 59.4 93.3 101.5 104.4 64.9 34.7 105.2 73.6 46.6 177.8 68.1 75.3 107.3 145.1 58.3 69.2 73.1 77.4 61.4 114.2 117.1 55.4 47.6 74.1 57.7 86.1 35.8 88.9 59.7 224.4 76.0 83.9 53.6 72.9 66.2 106.1 73.3 77.0 59.9 62.7 221.5 79.3 67.1 62.9 74.3 176.2 323.1 102.4 216.2 144.9 131.4 208.7 125.8 144.4 194.9 183.0 351.3 189.4 390.5 228.5 126.4 112.4 337.6 244.2 242.9 116.2 155.4 370.8 151.7 254.8 433.6 171.7 273.8 134.8 169.9 188.1 211.9 208.7 126.8 235.2 213.0 339.0 150.3 144.4 355.0 262.3 266.3 231.8 213.9 196.9 361.8 187.3 569.6 169.3 168.4 178.8 219.6 110.0 388.5 180.2 84.6 231.5 217.6 150.1 115.9 136.4 146.7 196.6 229.8 253.6 172.2 148.6 336.8 157.1 94.6 155.8 72.3 103.1 153.6 115.3 100.6 97.2 108.7 199.3 98.8 91.7 95.3 32.4 97.2 119.2 123.1 140.1 185.6 69.6 74.2 78.9 78.1 68.1 75.3 73.1 77.4 74.1 72.9 77.0 74.3 108.2 70.5 76.7 29.4 144.6 168.1 262.5 322.0 158.2 102.4 165.1 139.2 134.4 190.1 182.6 176.6 87.6 333.1 113.2 260.0 334.6 230.2 381.8 116.1 92.5 111.3 148.5 148.1 17.5 289.8 299.2 111.2 153.4 79.6 105.9 170.6 108.5 247.1 253.8 74.0 19.9 230.5 217.7 167.5 146.4 669.0 109.3 128.6 138.7 14.0 167.5 140.6 88.6 28.6 30.3 199.7 215.3 111.7 264.9 245.3 330.7 451.9 237.3 116.3 85.5 105.5 129.1 205.7 177.4 230.1 156.0 287.0 120.2 288.2 418.7 277.6 TWF2 "A6r, A6RP, PTK9L" ENSG00000247596 "Twinfilin actin binding protein 2" Q6IBS0 3 52228612-52246788 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 183.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 205.0;monocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053874 Uncertain Uncertain "Plasma membrane" NA NA 5900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA053874: AB_2682287" "unprognostic (4.24e-2)" "unprognostic (8.61e-2)" "unprognostic (2.18e-1)" "unprognostic (2.62e-2)" "unprognostic (2.70e-2)" "unprognostic (3.51e-2)" "unprognostic (5.46e-3)" "unprognostic (2.76e-1)" "unprognostic (6.56e-2)" "unprognostic (1.97e-1)" "unprognostic (2.58e-2)" "unprognostic (5.07e-2)" "unprognostic (4.31e-3)" "unprognostic (4.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.07e-2)" 50.3 32.0 16.6 28.1 16.4 28.3 39.0 12.9 26.5 35.7 13.2 32.4 21.8 35.4 0.6 44.5 27.9 17.2 94.8 17.3 15.4 31.2 29.3 34.9 33.3 15.5 13.7 29.5 17.3 6.8 18.3 15.8 16.0 29.1 4.8 0.9 36.7 18.7 183.4 32.4 33.6 14.1 15.4 54.8 24.5 14.2 14.7 21.3 23.8 4.3 15.1 36.2 36.4 18.0 24.9 59.8 10.7 28.6 29.1 47.5 35.7 56.0 55.9 49.1 43.4 32.3 51.6 89.9 36.5 27.1 39.2 37.5 11.9 60.0 4.2 52.4 34.0 89.6 38.0 78.9 49.1 54.3 139.6 46.4 28.8 50.4 12.8 21.9 82.9 50.1 21.0 36.0 20.7 21.7 65.0 117.1 30.4 15.2 171.9 27.0 22.0 92.0 22.3 38.4 13.6 59.7 19.7 74.7 109.2 4.2 19.3 40.5 105.9 55.1 68.4 50.4 47.4 37.4 35.9 45.6 125.9 143.8 73.7 97.5 167.8 143.4 107.7 169.1 95.0 109.1 112.4 114.6 159.7 83.1 86.5 108.9 242.0 93.7 181.6 150.6 141.9 149.6 16.6 16.4 12.9 26.5 17.3 15.4 15.5 13.7 16.0 15.4 14.7 18.0 44.3 6.4 7.8 2.0 50.7 17.2 29.5 59.2 12.5 14.0 29.9 28.2 28.8 27.1 23.7 12.9 0.0 42.4 77.0 64.4 37.2 86.8 3.1 34.2 27.5 35.9 22.1 17.7 7.5 100.8 84.3 34.0 18.8 86.3 40.6 28.4 31.1 13.3 205.0 6.7 4.2 20.2 30.5 108.8 56.7 2.7 35.1 111.8 33.8 3.7 202.4 14.9 97.9 3.5 3.5 103.2 55.7 33.8 25.2 20.3 65.5 25.4 12.2 5.1 52.6 16.1 38.6 1.7 25.1 27.2 15.3 22.6 64.4 53.7 23.9 31.3 TXLNB "C6orf198, dJ522B19.2, DKFZp451A175, MDP77" ENSG00000164440 "Taxilin beta" Q8N3L3 6 139240061-139291998 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "heart muscle: 82.0;skeletal muscle: 300.0;tongue: 189.1" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 260.7;Late spermatids: 67.2" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "Daudi: 5.0;HSkMC: 3.0;REH: 2.6;RPMI-8226: 3.8;U-698: 7.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030401, HPA030402, HPA030403" Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA030401: AB_2673459, HPA030402: AB_10602486, HPA030403: AB_2673461" "unprognostic (1.54e-1)" "unprognostic (7.01e-3)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (5.75e-3)" "unprognostic (2.94e-1)" "unprognostic (1.09e-2)" "unprognostic (6.00e-2)" "unprognostic (2.06e-1)" "unprognostic (8.10e-3)" "unprognostic (4.79e-1)" "unprognostic (5.15e-2)" "unprognostic (2.16e-4)" "unprognostic (2.19e-2)" "unprognostic (2.21e-1)" "unprognostic (2.65e-1)" "unprognostic (8.05e-4)" 1.1 1.5 0.7 2.5 0.5 0.2 2.2 0.4 0.8 0.9 0.3 1.3 0.6 2.8 0.6 4.4 1.8 2.2 82.0 1.2 1.5 0.1 0.3 1.2 3.1 1.1 1.1 11.4 0.2 2.8 1.2 0.6 1.8 3.0 0.9 0.3 2.4 0.3 300.0 0.6 1.5 2.2 2.0 2.2 0.9 3.8 0.8 7.7 0.3 189.1 3.5 1.1 0.6 1.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 1.3 0.2 3.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.4 0.2 0.2 0.5 0.6 0.1 0.0 0.3 2.6 1.1 3.8 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.9 0.0 0.0 0.0 0.1 0.8 1.4 7.1 0.2 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.8 0.1 0.3 0.0 0.8 0.1 0.0 0.7 0.1 0.1 0.1 0.1 0.1 0.7 0.5 0.4 0.8 1.2 1.5 1.1 1.1 1.8 2.0 0.8 1.9 2.0 0.0 0.0 4.9 5.9 0.5 0.3 0.6 0.0 0.1 2.0 0.5 260.7 0.0 1.6 1.8 0.0 0.1 0.7 0.0 0.0 0.0 38.5 4.3 0.3 4.9 0.0 2.7 8.7 0.0 0.0 11.4 0.5 0.4 0.0 0.2 0.7 0.4 1.7 0.0 17.4 0.0 0.0 6.6 6.0 67.2 0.6 4.1 5.4 12.2 0.6 6.5 2.1 2.5 4.0 0.0 0.0 2.2 7.4 0.1 0.0 0.0 17.8 0.1 0.0 25.8 2.2 3.8 1.2 0.3 0.4 0.0 2.0 5.9 0.0 0.1 TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 84000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008681: AB_1623682, HPA000994: AB_1080267" "unprognostic (5.11e-2)" "unprognostic (4.40e-3)" "unprognostic (4.40e-3)" "unprognostic (1.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.28e-2)" "unprognostic (4.02e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic favorable (2.04e-4)" "prognostic favorable (1.17e-6)" "unprognostic (1.49e-2)" "unprognostic (2.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" 60.3 182.3 89.8 45.5 92.4 64.7 58.0 94.6 98.2 57.4 92.4 65.3 84.0 50.0 51.7 79.8 64.1 49.4 122.3 87.9 90.7 91.5 149.5 44.7 59.2 92.9 91.3 75.8 59.2 99.1 43.4 47.3 91.9 59.3 63.6 43.0 59.5 52.5 159.4 60.5 64.3 48.3 91.2 65.7 76.1 48.8 97.0 50.9 67.7 180.1 59.9 59.0 54.0 91.7 52.8 80.4 75.4 126.8 115.2 125.0 81.3 70.8 108.1 114.8 128.7 87.9 52.1 133.3 64.2 116.8 54.5 76.1 151.7 127.4 66.1 93.6 131.8 147.7 91.7 125.4 94.6 189.6 125.8 162.3 98.9 101.9 79.3 99.5 118.2 78.4 157.7 104.1 106.1 80.3 87.5 128.2 60.0 170.3 95.3 75.3 79.5 92.6 116.4 84.8 99.9 98.3 70.2 148.1 125.3 61.3 103.6 165.9 83.7 120.5 95.0 69.8 65.9 81.4 64.2 128.6 111.0 109.5 74.1 30.2 173.5 32.3 102.5 194.3 108.9 140.4 101.2 109.0 223.4 133.8 116.4 108.6 59.3 145.4 170.1 167.1 110.9 224.3 89.8 92.4 94.6 98.2 87.9 90.7 92.9 91.3 91.9 91.2 97.0 91.7 68.9 60.9 53.0 12.1 66.4 83.5 87.7 154.0 108.1 105.6 124.3 137.7 105.4 88.6 82.5 69.9 39.6 213.2 62.8 128.5 303.3 93.0 19.6 45.7 70.6 73.7 89.5 114.0 8.3 106.2 275.8 74.0 75.4 57.2 69.1 148.0 81.0 122.7 173.4 116.1 10.3 132.4 95.6 100.5 80.7 36.8 56.5 80.7 78.2 8.4 91.9 168.9 77.2 9.0 13.5 82.5 104.3 50.8 79.5 52.7 252.2 213.7 49.0 59.4 19.7 61.1 67.1 49.1 42.4 124.5 89.8 207.1 62.4 287.0 179.6 87.1 TXNRD2 "SELZ, TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941820 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2 OS: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Approved Mitochondria,Cytosol NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Mitochondria, Cytosol" "CAB002007: , HPA003323: AB_1080396" "unprognostic (3.17e-2)" "unprognostic (8.72e-2)" "unprognostic (4.30e-1)" "unprognostic (9.71e-3)" "unprognostic (7.25e-2)" "unprognostic (6.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (2.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.49e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.47e-1)" "unprognostic (5.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" 10.5 44.4 11.9 8.9 12.0 14.5 12.3 18.1 19.3 11.7 21.2 14.9 10.3 10.6 6.2 10.2 10.6 6.2 30.0 12.9 11.9 24.8 65.4 13.6 9.1 11.8 12.1 16.5 15.9 13.5 14.4 9.8 11.5 26.8 4.6 4.4 15.4 8.2 23.0 10.9 12.0 5.1 11.3 16.9 26.4 14.6 12.4 4.9 15.2 16.1 6.1 11.8 10.4 11.8 19.4 39.2 3.5 14.9 6.9 9.6 8.8 18.8 21.1 31.8 23.4 36.7 19.4 10.9 43.2 19.0 32.7 33.2 17.8 25.2 12.1 21.6 46.5 18.8 34.4 22.4 12.9 21.1 8.4 9.2 18.5 16.2 13.8 12.9 91.3 2.2 106.4 17.4 24.8 47.1 7.2 30.1 17.7 46.9 27.6 10.5 85.2 10.0 19.3 21.0 19.1 16.4 32.0 39.9 21.8 5.8 33.7 27.6 52.2 23.0 139.5 19.8 38.4 17.6 14.0 6.9 22.4 15.5 30.3 2.7 10.5 5.8 3.5 8.2 2.6 3.9 3.0 3.2 7.8 2.6 3.9 3.2 0.9 3.8 7.9 2.9 2.1 4.6 11.9 12.0 18.1 19.3 12.9 11.9 11.8 12.1 11.5 11.3 12.4 11.8 5.6 16.0 23.6 11.1 10.3 4.2 23.1 15.1 3.4 22.1 11.4 9.1 16.7 15.7 15.7 20.2 10.4 60.7 8.8 14.7 58.7 22.0 26.4 9.8 8.4 14.4 1.2 33.1 9.2 32.0 24.3 12.4 23.4 10.0 1.3 27.6 8.9 49.5 25.9 10.1 8.5 16.9 20.3 22.0 7.8 18.2 15.5 14.6 5.4 10.3 27.2 18.7 10.3 8.5 7.2 22.3 13.9 9.1 12.2 17.8 15.6 52.0 16.6 11.0 6.6 11.3 13.3 10.9 14.0 6.4 5.3 42.0 11.4 36.4 16.4 15.7 TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 44.8;heart muscle: 59.9;skin 1: 145.0" "Cell type enriched" "Detected in some" 17 "Melanocytes: 2486.6" "Cancer enriched" "Detected in some" 262 "melanoma: 313.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "SK-MEL-30: 1395.0" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 51000 "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB002520: AB_564153, HPA000937: AB_1080437" "unprognostic (7.48e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-1)" "unprognostic (3.16e-3)" "unprognostic (8.10e-2)" "unprognostic (3.82e-3)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (4.46e-1)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-6)" "unprognostic (1.27e-1)" "unprognostic (5.99e-2)" "unprognostic (1.95e-2)" 0.3 0.0 0.1 0.6 0.4 0.2 4.9 0.3 0.9 0.0 44.8 2.2 5.0 0.0 1.2 10.0 0.2 4.5 59.9 2.6 0.0 16.2 0.0 3.7 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 5.3 2.7 1.3 0.0 4.8 145.0 4.7 1.8 0.1 0.0 2.1 1.1 0.3 0.0 0.0 7.5 0.0 1.1 0.4 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 25.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 1395.0 0.1 19.5 1.5 0.0 0.0 0.7 0.0 0.9 0.0 0.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.9 2.6 0.0 1.2 1.1 2.1 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 92.3 0.1 0.0 0.0 11.7 0.0 0.0 44.3 0.0 0.0 3.7 2.1 0.0 0.0 0.0 144.8 0.3 2.5 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 17.5 4.7 0.3 0.0 2486.6 0.0 0.0 15.9 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.6 0.0 0.0 1.4 0.7 0.7 0.0 16.8 0.0 0.5 0.0 0.0 0.2 UBAC1 "GBDR1, KPC2, UBADC1" ENSG00000130560 "UBA domain containing 1" Q9BSL1 9 135932969-135961373 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 301.3;tongue: 171.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 290.9;Late spermatids: 197.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 246.4;K-562: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005651 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 87000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA005651: AB_1858489" "unprognostic (8.41e-2)" "prognostic favorable (4.34e-6)" "unprognostic (2.10e-1)" "unprognostic (9.15e-2)" "unprognostic (4.11e-1)" "unprognostic (3.85e-2)" "unprognostic (7.68e-3)" "unprognostic (2.85e-1)" "unprognostic (4.37e-2)" "unprognostic (3.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.20e-1)" "prognostic favorable (3.58e-7)" "unprognostic (1.95e-3)" "unprognostic (9.46e-2)" "unprognostic (3.16e-2)" "unprognostic (5.78e-2)" 23.1 20.7 42.2 14.7 44.8 82.5 20.7 43.0 43.0 23.8 41.4 38.6 24.3 22.0 12.9 37.4 22.8 12.0 72.0 40.4 42.2 23.5 24.9 19.8 15.7 43.2 42.7 20.9 17.1 27.1 23.5 22.8 41.8 24.7 18.4 15.2 27.8 20.6 301.3 53.2 23.3 16.3 43.7 21.0 23.0 43.1 44.0 17.7 18.0 171.0 16.5 28.3 27.0 41.0 37.4 42.7 29.7 43.4 22.0 25.6 55.7 32.0 27.1 38.9 31.2 59.7 46.3 44.8 30.1 26.4 46.1 124.4 41.9 37.0 17.5 246.4 39.6 37.4 79.0 33.8 22.9 49.2 34.4 24.2 47.7 24.6 23.8 26.0 32.8 41.4 316.6 35.5 31.2 76.9 40.4 50.5 70.5 87.4 71.8 45.1 55.8 59.3 28.0 23.7 46.0 50.6 46.3 41.4 33.5 26.3 34.9 52.5 26.8 22.0 33.0 26.5 40.2 20.5 41.1 53.9 40.7 43.9 30.6 6.5 17.6 8.7 4.8 28.4 5.1 4.9 5.4 3.2 15.6 2.8 2.8 3.3 3.7 4.0 33.4 1.6 4.5 7.0 42.2 44.8 43.0 43.0 40.4 42.2 43.2 42.7 41.8 43.7 44.0 41.0 42.8 16.0 10.0 18.6 14.5 40.7 38.8 41.8 43.3 38.3 29.6 36.2 85.7 11.5 24.5 27.6 31.3 148.6 20.7 45.5 93.9 16.3 101.6 82.9 33.7 27.5 16.8 290.9 17.3 22.9 32.7 22.5 21.9 21.3 7.0 28.6 20.3 32.7 75.2 13.5 23.6 37.4 28.5 34.3 30.3 197.4 19.6 41.8 35.6 9.4 46.0 60.7 13.4 9.0 14.1 22.6 42.3 22.6 24.6 23.1 47.9 35.6 96.0 44.1 19.7 42.8 27.4 57.7 54.9 73.2 64.8 60.5 16.5 25.7 55.6 39.4 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448859-6496723 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.1;heart muscle: 16.8;retina: 28.3;skeletal muscle: 54.5;tongue: 13.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.0;Cardiomyocytes: 27.6;Excitatory neurons: 47.8;Granulosa cells: 45.5;Horizontal cells: 45.4;Inhibitory neurons: 35.3;Rod photoreceptor cells: 63.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 29.7;PC-3: 24.6;SCLC-21H: 23.1;U-266/70: 54.4;U-266/84: 52.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favorable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 1.2 1.4 14.3 0.4 14.6 0.0 1.1 16.5 26.1 2.1 1.8 5.3 0.3 0.8 1.0 0.4 0.7 0.4 16.8 17.9 11.4 3.4 1.2 0.1 0.1 12.0 7.9 2.6 0.6 0.1 3.2 0.0 11.6 3.5 0.3 28.3 0.8 5.5 54.5 1.5 1.4 0.7 5.6 0.2 2.9 0.7 10.1 0.3 1.2 13.9 0.2 0.3 1.3 17.7 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.7 0.0 5.3 0.0 0.0 0.3 0.0 24.6 0.1 0.0 11.5 0.0 0.0 23.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 54.4 52.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 14.6 16.5 26.1 17.9 11.4 12.0 7.9 11.6 5.6 10.1 17.7 0.2 0.0 0.0 5.5 0.3 1.3 0.5 0.5 0.0 30.0 0.4 1.0 27.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 5.9 0.0 0.0 0.2 0.4 1.0 5.4 0.0 47.8 0.2 0.0 3.6 1.1 0.1 0.0 45.5 0.0 1.0 0.1 45.4 35.3 0.0 0.0 0.3 0.3 0.3 4.1 0.1 0.0 2.8 0.0 9.4 0.0 12.1 5.4 0.1 0.0 6.8 1.8 0.9 0.0 0.2 0.0 63.6 0.0 3.2 1.4 0.1 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.0 UQCC1 "BFZB, C20orf44, CBP3, FLJ10850, UQCC" ENSG00000101019 "Ubiquinol-cytochrome c reductase complex assembly factor 1" Q9NVA1 20 35302566-35412031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 64.6;Inhibitory neurons: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034875 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA034875: AB_10603226" "unprognostic (9.66e-2)" "unprognostic (3.93e-1)" "unprognostic (3.45e-1)" "unprognostic (8.72e-3)" "unprognostic (4.01e-1)" "unprognostic (1.31e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (2.82e-2)" "unprognostic (7.66e-2)" "unprognostic (3.42e-2)" "unprognostic (7.01e-2)" "unprognostic (6.72e-3)" "unprognostic (3.23e-1)" "unprognostic (3.60e-1)" "unprognostic (5.27e-2)" "unprognostic (1.34e-2)" 19.4 30.0 22.0 13.8 24.3 4.6 16.5 21.9 27.7 20.1 20.9 26.0 18.9 18.6 22.9 18.8 20.6 12.6 55.3 22.4 23.0 28.6 27.1 15.8 17.9 24.1 23.5 19.8 15.9 37.2 23.9 14.9 26.6 19.7 25.8 29.5 18.7 18.4 106.8 16.3 19.3 18.5 19.9 19.7 23.0 17.6 22.9 21.2 22.3 105.7 21.9 20.1 18.0 22.8 20.2 28.6 33.5 32.2 34.1 38.4 4.8 38.5 43.3 70.7 48.1 97.7 39.4 66.6 68.5 26.1 60.7 53.5 60.0 70.0 52.6 19.0 24.2 89.2 41.3 80.3 22.7 54.2 25.6 37.6 72.3 37.9 48.8 51.2 24.6 53.5 39.9 23.9 50.0 26.8 58.6 29.2 25.4 42.0 61.5 31.4 50.0 37.9 67.6 26.2 46.4 28.7 32.9 148.9 34.0 28.1 23.9 34.6 23.5 46.2 28.8 25.9 34.6 30.1 37.2 26.5 79.7 31.1 36.8 28.6 10.2 14.2 14.8 14.3 18.3 12.3 13.7 14.7 16.0 15.7 16.7 14.7 0.3 22.3 10.2 14.4 14.2 12.6 22.0 24.3 21.9 27.7 22.4 23.0 24.1 23.5 26.6 19.9 22.9 22.8 7.0 0.0 7.8 51.6 7.0 6.4 9.3 18.1 6.8 20.7 7.8 5.8 44.0 10.0 11.8 16.5 8.4 22.9 5.3 13.9 60.7 18.2 15.1 10.5 8.5 10.5 12.0 5.2 64.6 13.1 15.7 9.2 7.7 6.9 8.2 17.5 6.1 14.2 11.6 18.5 68.9 9.1 18.3 6.6 3.9 8.6 10.5 5.8 14.2 33.7 13.2 16.7 10.3 44.2 50.3 19.1 6.6 12.0 5.0 8.4 10.9 19.4 14.8 22.8 6.6 9.6 11.9 24.6 18.2 6.2 5.3 17.4 6.2 19.7 13.2 9.6 UQCC2 "bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1" ENSG00000137288 "Ubiquinol-cytochrome c reductase complex assembly factor 2" Q9BRT2 6 33694293-33711727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 911.7;Late spermatids: 1207.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039111 Uncertain Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "Nuclear bodies" "HPA039111: AB_2676352" "unprognostic (3.58e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.93e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.35e-3)" "unprognostic (2.43e-2)" "unprognostic (5.93e-2)" "unprognostic (2.33e-2)" "unprognostic (7.43e-2)" "unprognostic (5.77e-2)" "unprognostic (3.88e-1)" "unprognostic (1.07e-1)" 38.9 69.6 100.5 37.3 102.8 45.3 45.3 103.3 140.9 48.4 97.6 43.3 34.3 61.5 58.4 59.2 40.0 20.8 267.2 100.1 106.6 66.9 83.3 33.9 35.6 102.5 102.2 33.4 61.2 46.8 78.0 29.3 102.9 55.4 44.0 104.3 53.0 28.6 228.8 42.9 28.5 52.4 102.4 43.2 49.5 104.1 104.4 45.7 42.9 197.9 40.8 46.1 42.8 107.9 207.7 144.2 162.8 139.4 130.9 129.8 125.5 116.4 117.3 167.7 162.6 233.9 84.5 84.4 180.3 143.5 244.1 109.0 111.7 164.5 138.6 108.0 187.7 163.3 87.3 327.6 215.9 153.8 127.2 136.2 257.4 131.7 204.7 91.0 120.4 158.9 178.4 165.9 190.4 220.9 149.0 315.9 97.3 158.4 167.6 106.5 130.7 279.9 116.2 191.5 273.1 97.1 127.9 191.7 165.6 84.1 168.3 382.2 110.5 178.0 151.1 115.9 242.0 126.8 193.1 146.6 53.7 229.7 211.0 32.7 88.5 18.2 76.1 141.6 93.6 152.4 95.0 87.6 108.6 116.1 98.7 88.0 8.4 81.6 120.9 133.2 110.7 123.8 100.5 102.8 103.3 140.9 100.1 106.6 102.5 102.2 102.9 102.4 104.4 107.9 18.5 28.9 29.3 8.1 54.2 58.5 96.8 193.0 61.5 108.7 96.0 100.3 911.7 74.4 119.8 77.3 50.1 134.7 34.0 112.4 391.3 103.4 342.3 46.6 78.7 54.1 99.7 105.0 8.9 179.7 124.4 88.5 90.7 39.1 59.5 90.0 41.4 166.1 218.8 70.7 10.2 94.5 154.6 67.8 55.6 1207.0 78.6 64.8 83.6 3.7 63.6 79.1 46.4 9.0 10.0 95.6 64.2 83.8 88.3 122.1 44.6 257.2 87.1 123.8 0.0 32.9 269.4 155.9 96.0 103.3 76.3 95.4 43.5 159.3 102.3 118.5 UQCR11 "QCR10, UQCR" ENSG00000127540 "Ubiquinol-cytochrome c reductase, complex III subunit XI" O14957 19 1597169-1605473 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 297.7;skeletal muscle: 311.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1792.1;Hepatocytes: 2200.3;Proximal enterocytes: 2007.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.90e-1)" "unprognostic (6.67e-3)" "unprognostic (1.78e-1)" "prognostic favorable (1.23e-4)" "unprognostic (5.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (5.42e-3)" "unprognostic (9.10e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.86e-4)" "unprognostic (1.03e-1)" "prognostic favorable (1.65e-4)" "unprognostic (2.40e-1)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (1.06e-2)" 71.0 80.2 74.9 20.6 79.6 39.7 60.5 79.4 103.7 46.8 78.6 91.7 59.7 46.4 18.4 71.6 43.6 25.0 297.7 76.4 76.7 103.4 136.4 48.7 27.4 76.5 77.7 35.5 49.5 46.8 62.7 24.1 76.6 62.0 22.8 13.8 53.9 30.9 311.8 50.4 62.6 22.6 75.6 60.9 77.2 24.7 78.3 24.1 52.6 109.7 19.3 60.9 51.4 79.0 68.9 75.7 34.7 74.5 60.8 40.7 79.9 54.3 45.4 55.5 48.8 121.5 47.3 47.4 51.8 41.8 12.3 46.8 55.5 61.0 26.5 65.0 163.1 40.6 87.3 114.0 60.6 66.1 57.9 62.8 62.6 35.2 41.6 28.6 50.8 66.9 94.8 73.1 36.2 111.5 67.7 72.4 94.8 59.2 176.0 40.4 36.2 148.9 74.6 158.4 69.6 65.9 39.3 86.4 99.7 27.9 59.3 65.1 66.7 44.3 30.0 129.9 57.7 110.4 101.2 54.4 82.6 69.9 64.8 619.6 421.3 521.9 282.7 367.9 287.1 390.0 341.7 316.6 360.5 333.8 324.3 314.1 496.7 273.7 354.9 448.4 407.7 872.4 74.9 79.6 79.4 103.7 76.4 76.7 76.5 77.7 76.6 75.6 78.3 79.0 300.4 269.2 379.1 20.5 287.6 0.0 189.6 0.0 206.6 135.2 715.6 798.8 1731.6 529.0 159.7 634.5 39.6 481.8 380.1 834.6 1792.1 665.4 178.2 290.5 220.2 282.4 452.6 451.6 17.8 811.6 632.1 262.0 342.0 243.5 199.3 152.6 463.3 2200.3 962.9 89.2 17.6 681.7 0.0 783.5 0.0 474.8 252.8 472.2 0.0 10.3 866.6 418.8 568.5 9.5 25.1 855.3 727.0 259.5 384.1 365.5 2007.4 1742.3 267.5 164.4 223.5 192.6 291.3 159.2 145.3 520.3 0.0 512.8 304.3 188.0 717.0 290.3 UQCRH "QCR6, UQCR8" ENSG00000173660 "Ubiquinol-cytochrome c reductase hinge protein" P07919 1 46303698-46316776 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042574 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA042574: AB_10960998" "unprognostic (2.24e-2)" "unprognostic (6.48e-2)" "unprognostic (5.62e-2)" "unprognostic (1.06e-3)" "unprognostic (6.34e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (4.63e-5)" "unprognostic (1.31e-1)" "unprognostic (3.15e-2)" "unprognostic (2.56e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-3)" "unprognostic (2.07e-2)" "unprognostic (3.77e-1)" "unprognostic (5.14e-2)" "unprognostic (1.04e-1)" 216.1 159.7 403.2 200.3 408.4 414.5 241.5 420.6 533.0 176.6 423.5 433.1 396.6 153.6 215.7 292.8 121.1 134.9 1012.8 410.2 421.1 363.4 261.5 121.6 257.5 417.7 404.1 227.8 215.9 403.4 144.7 142.4 411.3 147.8 418.4 436.6 278.5 177.2 932.8 172.0 291.0 146.8 408.8 143.2 256.0 77.7 420.4 312.4 138.0 1033.3 349.6 237.6 188.9 408.4 766.7 456.4 514.3 945.2 529.0 720.3 1070.8 501.7 311.3 435.2 372.5 883.1 416.1 750.2 653.2 474.0 777.9 537.8 742.2 778.7 650.8 563.1 1262.1 1854.5 1320.9 1215.3 313.6 1832.0 508.1 810.8 466.3 706.7 363.4 643.0 622.6 907.5 1803.3 814.1 675.1 613.9 830.6 1884.9 3043.4 950.6 917.8 858.9 840.5 2386.6 974.1 1679.4 1008.3 1180.4 806.7 1519.3 1628.1 1346.7 507.4 2232.3 541.3 410.8 528.9 589.2 935.7 546.9 1230.5 1185.4 593.1 1432.2 625.9 171.5 372.6 249.0 214.4 332.7 281.9 544.6 307.8 283.6 481.5 433.1 346.2 313.0 69.3 221.4 297.8 318.2 340.7 620.8 403.2 408.4 420.6 533.0 410.2 421.1 417.7 404.1 411.3 408.8 420.4 408.4 249.6 105.8 148.5 26.4 523.3 457.8 703.8 1298.7 544.7 269.7 669.2 942.3 1897.2 479.0 505.3 393.6 166.8 651.5 273.8 761.5 2099.3 479.4 65.2 239.0 321.1 293.0 502.5 453.8 49.7 350.6 816.2 285.8 452.1 341.1 283.6 432.7 355.6 612.9 724.5 102.6 53.9 1148.6 612.3 711.1 410.1 69.1 308.8 516.2 489.2 12.2 606.2 408.1 365.6 22.1 22.2 419.9 789.0 284.4 703.3 710.0 944.4 1521.9 213.3 454.0 328.7 358.3 372.6 184.3 337.8 935.4 526.9 650.2 318.0 396.5 1298.2 866.4 UQCRHL ENSG00000233954 "Ubiquinol-cytochrome c reductase hinge protein like" A0A096LP55 1 15807169-15809348 "Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 16.6" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 444.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA042574 Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042574: AB_10960998" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-1)" "unprognostic (3.70e-2)" "unprognostic (3.19e-2)" "unprognostic (7.10e-2)" "unprognostic (4.01e-3)" "unprognostic (4.83e-1)" "unprognostic (6.76e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-1)" "unprognostic (9.67e-3)" "unprognostic (9.76e-3)" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (9.70e-3)" "unprognostic (1.02e-1)" 3.6 2.2 1.3 0.3 1.3 1.1 2.8 3.0 1.6 3.2 0.8 4.4 0.3 2.3 0.7 4.6 2.7 0.3 16.6 1.3 1.1 5.8 3.4 2.4 0.3 1.6 1.3 3.8 3.0 0.1 2.7 0.1 1.6 2.6 0.2 2.9 3.3 0.1 10.4 3.1 3.3 0.2 0.7 2.8 3.5 1.7 1.5 0.3 2.4 0.1 0.2 3.0 3.2 2.3 0.2 0.1 0.8 0.8 0.2 0.2 0.3 0.1 0.1 0.0 0.1 0.2 0.6 0.3 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.6 0.1 0.3 0.6 0.1 0.1 0.2 0.3 0.1 0.2 0.1 0.1 0.3 0.0 0.4 0.2 0.5 0.0 0.5 0.1 0.4 0.4 0.1 0.3 0.3 0.2 0.2 0.0 0.4 0.5 0.4 0.2 0.5 0.2 0.2 0.2 0.7 0.1 0.5 0.3 0.3 0.2 0.5 0.2 0.3 0.2 0.5 0.2 1.8 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.2 0.4 0.3 0.3 1.6 0.4 0.2 0.4 0.2 0.2 1.3 1.3 3.0 1.6 1.3 1.1 1.6 1.3 1.6 0.7 1.5 2.3 1.4 0.0 1.1 6.2 12.3 0.0 39.0 0.0 1.8 3.8 3.1 6.2 444.8 24.3 0.6 9.2 6.2 21.4 4.1 6.1 23.5 1.1 3.0 4.0 6.7 10.7 7.3 6.6 5.3 0.7 21.5 13.9 1.5 4.6 2.5 9.7 17.9 23.1 20.6 1.7 5.4 12.6 0.0 48.3 0.0 3.6 11.1 11.9 0.0 0.0 12.9 3.0 16.5 1.0 2.9 0.6 6.1 12.4 7.8 31.9 11.5 10.3 0.0 6.9 6.6 33.2 12.7 6.2 12.5 5.5 0.0 23.5 5.4 3.9 15.4 31.1 USH2A "RP39, USH2" ENSG00000042781 Usherin O75445 1 215622891-216423448 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "liver: 7.0;retina: 19.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 202.3;Early spermatids: 49.3;Rod photoreceptor cells: 165.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (3.92e-3)" "unprognostic (1.74e-1)" "unprognostic (2.97e-2)" "unprognostic (5.38e-2)" "unprognostic (9.19e-2)" "unprognostic (2.04e-1)" "unprognostic (6.62e-4)" "unprognostic (1.00e-1)" "unprognostic (3.68e-1)" "unprognostic (2.06e-1)" "unprognostic (6.07e-3)" "unprognostic (3.15e-2)" "unprognostic (3.28e-11)" "unprognostic (2.02e-2)" "unprognostic (1.91e-1)" "unprognostic (3.35e-2)" "unprognostic (9.09e-4)" 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.2 0.1 7.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 5.0 1.5 0.0 0.0 202.3 0.0 0.0 0.0 0.0 0.0 49.3 0.3 0.0 0.6 0.0 0.0 17.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 12.3 0.0 3.3 10.4 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 6.1 0.0 3.0 3.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 165.8 0.0 0.2 0.2 1.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 UTS2R GPR14 ENSG00000181408 "Urotensin 2 receptor" Q9UKP6 17 82371400-82375586 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;testis: 3.2;thyroid gland: 1.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "stomach cancer: 0.7;testis cancer: 2.2;thyroid cancer: 1.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 6.2;U-266/70: 15.2;U-266/84: 2.7" NA NA "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "unprognostic (1.55e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.92e-1)" "unprognostic (1.46e-2)" "unprognostic (8.26e-2)" "unprognostic (2.30e-2)" "unprognostic (3.98e-1)" "unprognostic (6.38e-2)" "unprognostic (4.44e-2)" "unprognostic (8.73e-2)" "unprognostic (1.81e-1)" "unprognostic (1.32e-1)" "unprognostic (7.84e-2)" 0.0 0.0 0.3 0.1 0.6 0.0 0.1 0.0 1.5 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.3 0.1 3.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 1.8 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 15.2 2.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VDAC1 "MGC111064, PORIN" ENSG00000213585 "Voltage dependent anion channel 1" P21796 5 133971871-134004975 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1045.7;tongue: 812.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005885, HPA030780, CAB072343" Supported NA NA 1300000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "CAB005885: AB_2214787, CAB072343: , HPA030780: AB_2673608" "prognostic unfavorable (5.30e-4)" "unprognostic (7.63e-3)" "unprognostic (3.07e-3)" "unprognostic (2.01e-1)" "unprognostic (5.11e-3)" "prognostic unfavorable (4.90e-4)" "prognostic unfavorable (8.49e-4)" "prognostic unfavorable (2.87e-5)" "unprognostic (1.81e-1)" "unprognostic (1.86e-1)" "unprognostic (1.20e-2)" "unprognostic (2.64e-1)" "unprognostic (3.19e-2)" "unprognostic (8.98e-2)" "unprognostic (1.78e-1)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" 96.3 129.8 104.8 96.2 113.5 53.9 106.2 112.8 137.4 62.8 149.0 154.1 265.7 54.4 196.9 172.3 61.5 90.3 403.5 116.7 122.3 200.9 206.2 79.3 89.6 113.4 105.1 60.8 99.7 181.8 63.4 104.5 118.3 82.4 166.4 316.0 132.9 72.5 1045.7 113.9 179.1 90.7 101.1 60.2 163.6 37.5 117.3 90.9 68.5 812.0 129.3 108.3 91.0 106.4 364.5 315.8 282.8 295.3 277.5 385.0 398.0 398.1 292.2 386.5 395.2 650.0 282.9 497.4 291.5 418.0 515.1 278.2 403.4 701.2 480.7 296.1 331.7 287.3 308.9 526.0 282.2 266.5 272.9 353.3 368.5 301.1 333.0 385.3 381.2 248.0 260.1 197.8 511.8 404.5 326.3 264.1 198.5 555.2 264.3 296.5 282.6 474.3 608.6 450.0 315.0 177.7 253.7 305.2 416.0 385.9 147.0 257.6 311.6 361.4 241.6 335.9 530.2 262.9 278.3 309.4 537.1 351.9 420.7 24.9 83.2 30.3 54.5 118.4 60.0 58.3 55.6 57.3 140.7 40.5 38.8 43.8 6.9 87.7 105.1 41.1 74.5 72.9 104.8 113.5 112.8 137.4 116.7 122.3 113.4 105.1 118.3 101.1 117.3 106.4 89.9 105.8 63.1 21.2 101.9 204.8 246.6 250.8 128.7 463.6 163.7 98.3 276.0 198.8 133.2 126.9 81.3 372.4 94.9 333.1 729.8 303.4 68.7 140.8 161.1 120.7 104.1 96.7 41.5 302.6 471.4 136.9 225.8 184.6 121.8 163.9 57.1 203.9 332.7 519.9 40.6 202.7 189.2 130.6 243.5 50.3 95.7 165.7 249.1 31.9 315.8 277.0 60.8 24.1 23.8 300.7 227.7 112.1 162.0 353.6 415.8 585.3 121.2 257.2 85.5 132.8 171.4 10.9 32.7 275.5 232.9 325.6 111.0 229.1 326.7 265.1 VDAC3 HD-VDAC3 ENSG00000078668 "Voltage dependent anion channel 3" Q9Y277 8 42391624-42405937 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 385.2;skeletal muscle: 914.4;tongue: 942.7" "Cell type enhanced" "Detected in all" "Spermatocytes: 403.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026864 Uncertain Supported Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA026864: AB_1858733" "unprognostic (2.55e-2)" "unprognostic (1.96e-2)" "unprognostic (9.88e-3)" "unprognostic (4.40e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-1)" "unprognostic (4.98e-2)" "unprognostic (2.25e-2)" "unprognostic (1.40e-2)" "unprognostic (5.76e-2)" "unprognostic (3.74e-1)" "unprognostic (1.19e-2)" "unprognostic (6.16e-3)" "unprognostic (2.96e-2)" "unprognostic (1.76e-1)" "unprognostic (8.78e-3)" "unprognostic (6.94e-3)" 67.5 76.2 117.3 59.1 119.4 92.1 70.3 116.8 150.6 53.7 115.4 106.9 79.8 63.5 68.6 99.9 85.8 56.0 385.2 121.1 130.8 108.8 92.9 51.9 66.3 122.7 119.3 61.6 64.6 92.4 58.9 63.9 139.2 69.5 106.4 123.1 61.6 81.3 914.4 54.1 73.0 92.8 114.1 67.3 72.1 114.5 118.6 80.1 83.3 942.7 79.3 78.9 59.8 113.8 226.3 225.7 174.5 185.9 146.3 126.6 84.8 180.0 151.1 225.4 205.2 173.4 190.4 235.8 165.0 153.7 196.3 142.5 238.4 194.1 244.7 117.2 196.6 352.9 138.4 250.2 105.2 172.0 190.1 98.6 143.3 171.6 80.9 149.6 279.8 201.3 284.4 158.6 235.7 126.4 373.3 197.1 205.2 285.6 144.5 193.6 322.1 165.3 245.7 198.8 156.8 133.3 112.1 132.8 116.1 126.4 279.9 129.9 149.8 86.6 150.0 217.7 174.0 145.2 264.1 266.9 117.5 238.0 150.9 142.8 165.3 183.4 145.8 167.2 148.7 126.5 155.6 146.5 222.7 96.6 152.7 147.7 82.8 125.8 155.6 163.0 202.5 360.5 117.3 119.4 116.8 150.6 121.1 130.8 122.7 119.3 139.2 114.1 118.6 113.8 78.1 44.8 24.4 50.6 59.8 64.5 81.1 197.8 58.1 85.9 53.0 73.9 321.2 55.8 82.8 66.2 35.5 145.5 91.9 65.7 307.2 116.3 151.1 112.8 56.7 70.5 47.8 186.4 63.2 90.0 112.1 81.5 41.3 47.1 55.2 100.6 68.2 60.4 139.7 138.0 78.9 86.1 177.0 58.5 77.8 146.4 69.3 107.7 72.9 26.2 130.1 72.9 83.4 38.2 34.7 84.9 86.7 97.4 75.9 48.9 125.3 177.5 142.1 94.5 65.7 146.4 123.8 403.7 156.3 82.3 70.8 58.3 79.7 94.2 124.8 70.4 VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 663.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 442.7;Inhibitory neurons: 243.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 663.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 125.9;Hep G2: 124.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053808: AB_2682270" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.90e-4)" "unprognostic (4.90e-2)" "unprognostic (5.48e-2)" "unprognostic (2.81e-2)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-1)" "unprognostic (5.14e-4)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.19e-3)" "unprognostic (1.51e-2)" 0.8 27.5 100.4 1.4 143.0 0.1 6.2 12.9 663.3 13.5 0.0 4.6 0.2 1.1 0.0 47.9 2.0 0.2 39.7 105.8 12.3 1.9 20.8 2.9 0.1 21.6 0.0 3.6 1.2 0.2 2.7 5.4 19.7 3.9 5.4 18.6 9.7 0.8 1.3 13.8 0.3 1.1 0.0 0.3 1.4 0.8 4.3 1.1 0.8 2.9 7.3 1.5 26.3 188.8 0.7 0.1 1.4 21.2 2.4 3.0 0.1 0.0 0.0 0.0 0.6 0.3 13.6 0.0 0.0 0.0 0.0 125.9 0.8 4.0 0.0 0.0 0.5 0.0 0.1 124.4 0.0 0.0 0.3 0.9 6.0 0.0 2.9 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 0.1 21.0 6.7 0.0 0.1 0.1 0.0 0.0 0.4 9.3 8.5 0.0 0.0 0.0 4.9 0.0 0.1 0.0 4.2 0.0 0.0 2.4 0.1 0.0 0.0 3.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 143.0 12.9 663.3 105.8 12.3 21.6 0.0 19.7 0.0 4.3 188.8 0.1 0.0 0.5 41.1 0.0 18.2 29.8 54.3 59.2 8.8 4.9 19.7 30.8 4.3 18.0 0.0 0.0 0.3 0.1 2.2 1.9 0.1 5.1 0.0 0.1 1.1 1.2 0.0 442.7 0.2 0.2 5.9 0.0 0.1 0.0 0.1 0.0 17.8 0.6 3.3 243.2 7.1 18.3 0.3 0.8 6.5 0.6 0.5 3.6 54.4 0.6 3.7 0.0 36.7 42.9 0.2 1.0 0.0 0.0 15.0 0.0 4.0 0.8 14.7 0.0 0.2 1.3 1.7 0.9 85.5 20.2 0.4 0.8 1.8 5.6 14.2 VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 100.9;fallopian tube: 32.7;pancreas: 30.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 62.3;Collecting duct cells: 55.2;Ductal cells: 83.6;Endometrial ciliated cells: 42.7;Exocrine glandular cells: 34.2;Glandular and luminal cells: 79.1" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 100.9 0.0 0.0 15.3 0.0 0.0 0.4 4.5 5.0 0.4 32.7 5.0 0.2 0.0 0.0 17.3 1.1 0.7 0.0 0.0 0.0 0.1 30.1 0.0 0.1 0.8 0.0 3.0 0.0 0.0 22.1 7.8 0.2 2.8 0.0 0.1 0.0 0.0 3.6 1.1 0.1 0.1 0.0 0.0 0.0 3.2 0.1 0.0 1.0 0.1 1.7 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 7.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 4.2 0.1 1.2 0.0 0.0 244.8 0.1 29.9 14.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 2.5 6.9 0.0 0.0 62.3 18.4 1.1 0.0 22.6 55.2 0.0 3.4 1.1 0.0 0.0 83.6 2.5 42.7 4.4 0.6 0.0 0.0 0.8 34.2 1.4 0.4 0.0 79.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 6.1 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.3 11.3 0.0 0.0 0.0 1.6 0.0 0.3 8.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 3.0 0.5 0.0 0.0 4.8 ZC2HC1C "C14orf140, FAM164C" ENSG00000119703 "Zinc finger C2HC-type containing 1C" Q53FD0 14 75064109-75119502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 23.9;testis: 55.3" "Group enriched" "Detected in many" 5 "Early spermatids: 165.2;Late spermatids: 195.1;Spermatocytes: 198.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA050928, HPA065062" Enhanced Approved "Nuclear speckles,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA050928: AB_2681277, HPA065062: AB_2732728" "unprognostic (8.01e-2)" "unprognostic (2.01e-2)" "unprognostic (9.61e-2)" "unprognostic (8.01e-2)" "unprognostic (1.97e-3)" "unprognostic (6.00e-2)" "unprognostic (8.94e-2)" "unprognostic (1.20e-2)" "unprognostic (3.71e-3)" "unprognostic (3.22e-2)" "unprognostic (1.09e-3)" "unprognostic (2.26e-1)" "prognostic favorable (4.63e-13)" "unprognostic (4.69e-3)" "unprognostic (7.37e-2)" "unprognostic (3.12e-1)" "unprognostic (1.81e-1)" 1.1 2.5 2.5 0.6 2.7 0.4 1.7 2.8 2.9 1.8 5.1 2.7 3.1 1.3 23.9 1.3 11.0 1.6 5.2 2.4 2.9 5.5 8.4 2.5 0.2 3.1 3.7 0.6 5.1 6.9 6.1 0.8 2.9 1.3 2.4 2.6 2.9 3.4 4.7 1.6 2.4 1.0 2.8 0.8 1.6 55.3 2.9 2.3 7.0 1.5 0.5 1.4 0.6 3.3 3.8 2.8 0.3 3.3 0.2 0.0 1.8 0.3 1.1 1.4 0.8 4.8 6.9 3.3 2.6 0.4 2.6 1.0 0.0 0.0 1.2 3.9 0.3 0.6 1.0 2.3 2.5 0.0 1.8 0.3 0.4 1.6 0.0 1.7 1.1 0.2 5.8 1.0 0.7 0.6 0.4 0.3 0.7 2.4 1.8 0.0 0.2 0.7 4.3 0.3 5.7 1.3 2.4 2.0 1.5 0.6 2.9 0.9 0.7 0.9 0.9 1.0 0.8 4.0 4.9 1.1 1.4 0.4 0.6 0.3 0.0 0.2 0.6 0.0 0.1 0.4 0.3 0.1 0.1 0.2 0.1 0.1 0.1 1.2 0.1 0.2 0.9 0.1 2.5 2.7 2.8 2.9 2.4 2.9 3.1 3.7 2.9 2.8 2.9 3.3 0.8 6.4 9.7 2.0 0.9 1.8 1.9 1.3 4.6 4.5 7.9 5.1 7.0 2.8 6.6 11.0 10.4 2.3 1.6 2.5 3.9 4.6 165.2 21.0 2.1 2.0 5.3 0.4 2.4 1.4 1.1 2.5 1.1 1.9 1.3 1.1 2.9 4.7 1.7 11.8 2.1 2.3 0.0 1.0 0.7 195.1 3.1 1.0 3.6 1.0 0.9 3.0 8.2 0.5 1.0 1.6 0.6 2.6 0.6 2.8 4.2 7.4 32.5 8.5 6.6 5.2 2.0 198.5 5.5 1.9 0.9 5.1 0.9 2.3 3.9 1.3 ZNF233 FLJ38032 ENSG00000159915 "Zinc finger protein 233" A6NK53 19 44259880-44275317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 14.2" "Group enriched" "Detected in some" 4 "Early spermatids: 40.9;Spermatocytes: 38.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 6.9;U-266/84: 7.6" HPA020975 Uncertain Approved Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA020975: AB_1859145" "unprognostic (2.26e-1)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-1)" "unprognostic (1.60e-1)" "unprognostic (3.72e-2)" "unprognostic (7.37e-3)" "unprognostic (2.77e-2)" "unprognostic (9.07e-3)" "unprognostic (1.48e-1)" "unprognostic (4.20e-3)" "unprognostic (1.65e-1)" "unprognostic (6.28e-3)" "unprognostic (6.88e-2)" "unprognostic (3.47e-2)" "unprognostic (2.71e-4)" "unprognostic (1.55e-1)" 0.4 1.1 1.8 1.1 1.9 1.8 1.5 3.4 3.1 0.7 0.4 3.0 0.9 0.4 1.6 0.6 1.3 0.9 3.2 1.5 1.8 1.3 0.5 0.6 1.3 1.2 0.1 0.5 0.8 1.7 3.1 1.3 1.5 2.7 1.3 4.9 0.9 1.0 1.7 1.6 1.0 0.4 0.3 1.3 1.1 14.2 0.9 1.5 1.9 0.6 0.6 0.8 0.4 2.5 0.4 1.8 2.0 1.9 2.2 0.4 0.5 0.7 0.6 0.7 1.2 1.5 2.1 0.6 1.9 0.6 1.1 0.6 0.0 0.5 0.8 0.3 2.4 1.0 2.5 1.7 1.5 0.7 0.8 0.5 0.3 0.5 1.3 2.9 0.9 0.7 0.8 3.8 0.1 0.7 0.6 0.5 2.1 0.4 0.3 1.2 0.2 0.8 0.4 1.2 2.8 4.4 0.7 0.5 1.3 3.7 3.5 1.0 0.3 0.6 0.4 0.4 0.4 6.9 7.6 1.2 3.0 0.5 0.9 1.5 0.3 0.2 0.5 0.3 0.4 0.9 0.4 0.3 0.1 1.3 0.6 0.7 0.7 1.1 0.3 1.3 0.7 0.1 1.8 1.9 3.4 3.1 1.5 1.8 1.2 0.1 1.5 0.3 0.9 2.5 0.5 0.0 0.5 2.6 0.4 0.0 0.2 0.2 0.0 3.7 1.1 0.4 4.6 0.0 0.3 0.0 0.0 0.5 0.2 0.3 0.0 0.6 40.9 1.3 0.3 0.9 1.2 0.4 9.0 0.0 0.1 0.6 0.5 0.5 0.0 0.7 0.0 0.0 0.6 0.0 7.9 0.2 2.0 0.0 0.0 8.5 0.6 0.1 0.0 1.0 0.0 1.9 0.0 4.5 5.7 0.1 0.1 0.7 0.0 0.5 0.8 0.0 0.4 4.0 0.0 0.6 0.4 38.6 1.9 0.0 0.0 0.0 0.3 1.1 0.4 0.1 ZNF629 "KIAA0326, ZNF65" ENSG00000102870 "Zinc finger protein 629" Q9UEG4 16 30778456-30787205 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019550, HPA056051" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Golgi apparatus" "HPA019550: AB_1859386, HPA056051: AB_2683020" "unprognostic (1.03e-2)" "unprognostic (2.15e-2)" "unprognostic (1.24e-1)" "unprognostic (2.67e-1)" "unprognostic (3.17e-1)" "unprognostic (6.38e-2)" "unprognostic (6.14e-2)" "unprognostic (2.98e-2)" "unprognostic (3.15e-1)" "unprognostic (6.24e-2)" "unprognostic (4.87e-3)" "unprognostic (2.66e-2)" "prognostic favorable (4.57e-10)" "unprognostic (8.41e-2)" "unprognostic (1.96e-1)" "unprognostic (5.71e-2)" "unprognostic (9.70e-2)" 5.6 9.0 5.6 3.0 6.0 4.1 5.7 7.1 5.9 6.5 4.3 6.8 5.5 8.0 4.3 5.1 6.6 3.6 12.6 5.9 6.1 7.8 4.3 5.3 1.9 6.2 6.7 6.8 5.9 15.0 6.6 3.6 5.6 6.3 4.5 7.8 6.5 6.0 9.7 8.6 5.3 6.8 5.0 4.0 7.3 4.1 7.0 3.9 5.9 9.6 2.3 6.5 5.1 5.5 9.8 15.8 23.9 18.5 11.5 10.6 3.6 10.8 15.6 16.6 14.0 9.7 8.8 1.8 10.2 17.6 5.2 11.4 11.7 14.3 11.0 0.4 17.6 13.6 14.0 10.2 12.3 4.8 8.0 17.7 10.5 10.3 8.6 13.0 8.9 0.8 20.2 0.4 14.6 20.8 7.2 6.3 12.6 4.7 6.4 24.3 18.4 0.8 13.9 15.9 22.6 25.3 10.5 19.4 2.6 7.8 14.6 17.4 10.8 15.5 10.1 10.6 8.3 0.3 0.1 0.5 10.2 11.9 5.3 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.3 0.1 0.6 0.0 0.1 5.6 6.0 7.1 5.9 5.9 6.1 6.2 6.7 5.6 5.0 7.0 5.5 4.9 19.2 9.4 5.9 2.6 1.9 3.4 4.3 5.7 16.7 4.2 3.4 28.3 4.3 6.5 9.2 4.2 1.3 1.6 5.4 1.9 8.7 1.7 5.1 9.5 8.0 11.5 4.6 2.4 8.0 0.6 5.3 7.1 5.3 2.5 10.7 8.2 4.7 4.4 16.8 3.7 7.9 6.1 5.2 3.0 4.7 9.3 2.6 1.8 1.0 7.7 13.4 1.0 4.5 3.4 10.9 5.0 4.5 3.0 4.8 5.1 4.3 5.9 12.4 0.0 6.7 5.6 4.6 1.5 3.8 1.8 0.5 1.4 8.3 9.0 3.8 ZNF784 MGC75238 ENSG00000179922 "Zinc finger protein 784" Q8NCA9 19 55620741-55624566 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059676 Uncertain Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA059676: AB_2684102" "unprognostic (4.67e-2)" "unprognostic (8.13e-2)" "unprognostic (4.03e-1)" "unprognostic (6.46e-3)" "unprognostic (1.17e-1)" "unprognostic (2.63e-2)" "unprognostic (2.28e-1)" "unprognostic (9.44e-2)" "unprognostic (4.74e-1)" "unprognostic (1.26e-1)" "unprognostic (9.11e-3)" "unprognostic (4.86e-2)" "unprognostic (3.48e-3)" "unprognostic (3.87e-1)" "unprognostic (7.93e-2)" "unprognostic (5.10e-2)" "prognostic favorable (1.02e-4)" 4.5 8.5 3.0 3.0 2.9 6.2 5.3 4.3 3.9 8.6 2.2 12.8 8.3 10.7 3.8 7.2 9.2 2.7 13.9 2.8 2.2 7.8 11.5 4.8 3.5 3.6 2.7 11.8 11.3 4.2 7.7 2.6 2.5 11.2 3.3 4.4 6.7 3.7 42.8 6.7 10.2 3.6 2.3 9.1 8.9 5.4 2.9 2.0 7.4 16.0 2.8 10.6 6.6 3.6 4.6 6.4 5.8 3.1 2.2 2.9 5.5 4.7 2.9 2.6 3.5 3.2 5.0 5.5 4.0 3.3 2.0 2.5 1.7 4.1 1.8 3.0 16.7 5.1 5.1 4.1 4.4 4.2 5.3 4.0 4.4 2.2 2.8 4.2 1.7 7.7 6.1 5.5 4.0 4.4 3.3 4.8 5.7 3.5 13.7 6.2 3.9 6.2 4.8 11.5 6.5 8.7 7.7 3.6 2.2 3.8 3.9 7.4 5.4 3.0 2.9 1.9 3.9 6.3 2.8 3.2 4.6 3.1 2.6 0.0 0.4 0.6 0.1 0.4 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.2 0.2 0.3 0.3 0.2 0.0 0.1 3.0 2.9 4.3 3.9 2.8 2.2 3.6 2.7 2.5 2.3 2.9 3.6 1.9 0.0 7.4 1.6 3.4 0.9 4.7 1.5 2.8 4.7 2.2 3.2 12.3 8.6 1.9 0.0 2.1 5.5 1.3 10.9 3.9 4.0 2.1 2.7 2.5 2.3 5.4 4.4 0.5 4.1 2.4 3.2 1.5 3.2 2.5 5.5 3.9 6.8 3.5 8.4 0.6 6.2 6.1 3.5 1.0 0.1 4.1 2.4 0.0 1.0 4.5 4.2 0.0 1.5 1.1 4.5 7.4 2.6 2.3 2.1 11.2 5.2 2.2 11.0 13.1 2.9 2.7 0.6 2.3 1.8 1.3 10.1 2.0 7.7 5.5 3.7 ZNF843 MGC46336 ENSG00000176723 "Zinc finger protein 843" Q8N446 16 31432593-31443160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 4.6;Cardiomyocytes: 5.3;Prostatic glandular cells: 3.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;EFO-21: 1.8;HMC-1: 1.6" "HPA030911, HPA030912, HPA077945" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nuclear speckles" "HPA030911: AB_2673656, HPA030912: AB_10670434, HPA077945: " "unprognostic (9.27e-2)" "unprognostic (1.32e-1)" "unprognostic (3.43e-3)" "unprognostic (9.24e-2)" "unprognostic (1.33e-1)" "unprognostic (6.25e-3)" "unprognostic (2.86e-1)" "unprognostic (8.30e-3)" "unprognostic (3.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-3)" "unprognostic (2.93e-3)" "unprognostic (5.96e-3)" "unprognostic (1.23e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-5)" "unprognostic (1.17e-1)" 0.6 0.5 1.5 0.3 1.2 0.3 0.6 2.5 1.3 1.0 0.0 0.4 0.2 1.0 0.7 0.4 1.1 0.7 1.7 1.6 1.9 0.6 0.4 0.3 0.3 1.1 1.4 3.0 2.1 0.9 1.5 0.4 0.9 0.6 0.1 1.1 1.5 0.8 2.2 0.9 0.3 0.5 1.1 0.4 0.4 0.5 1.8 0.2 1.0 0.8 0.2 0.5 0.6 0.9 0.1 0.3 0.2 1.2 2.3 0.6 0.0 0.2 0.2 0.0 0.1 0.1 0.3 0.0 1.8 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.2 1.6 1.2 0.3 0.0 0.1 0.8 0.0 0.2 0.2 0.2 0.6 0.8 0.1 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.7 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.8 0.0 0.2 0.1 0.1 0.0 0.1 0.4 1.0 0.2 0.2 0.7 0.1 0.4 0.2 0.2 0.7 0.1 0.2 0.1 0.4 0.7 1.7 0.1 0.2 0.1 1.0 1.5 1.2 2.5 1.3 1.6 1.9 1.1 1.4 0.9 1.1 1.8 0.9 0.5 0.0 0.5 2.9 0.3 0.8 4.6 0.1 0.0 2.2 0.9 1.3 5.3 0.0 0.7 0.0 2.1 0.3 0.1 0.3 0.0 0.3 0.2 0.4 2.0 1.0 1.2 0.0 1.4 0.2 0.1 1.4 0.0 0.4 1.3 1.4 1.8 0.3 0.6 0.0 1.7 0.0 0.0 0.3 2.1 0.0 1.5 0.9 0.0 0.0 0.1 1.4 2.1 1.0 1.3 0.1 0.1 1.5 0.1 3.6 0.0 0.4 0.0 1.9 0.0 2.8 1.3 0.4 0.7 0.1 1.4 0.3 1.2 0.8 0.1 1.9 ZSCAN1 "FLJ33779, ZNF915" ENSG00000152467 "Zinc finger and SCAN domain containing 1" Q8NBB4 19 58034025-58054631 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.8;pituitary gland: 15.9;testis: 8.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 11.7;Early spermatids: 28.2;Endometrial ciliated cells: 21.8;Late spermatids: 19.6;Spermatocytes: 13.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.0;HMC-1: 2.1;NTERA-2: 2.1;T-47d: 3.1" HPA007938 Uncertain Approved Nucleoli NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA007938: AB_1080768" "unprognostic (1.60e-3)" "unprognostic (2.44e-1)" "unprognostic (2.21e-1)" "unprognostic (3.58e-1)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (1.97e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-1)" "prognostic favorable (7.36e-4)" "unprognostic (1.41e-2)" "unprognostic (3.81e-2)" "unprognostic (1.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.32e-1)" "unprognostic (2.47e-2)" "unprognostic (3.60e-1)" 0.1 0.9 3.7 0.0 2.7 0.1 0.9 4.1 4.6 1.2 1.4 0.3 0.0 0.6 6.1 0.1 2.1 0.2 0.5 3.6 7.8 2.6 0.1 0.5 0.0 4.0 5.3 0.6 1.0 2.6 15.9 0.2 3.1 2.4 0.0 2.3 0.4 0.8 0.0 0.2 0.1 0.1 2.1 0.2 0.1 8.7 5.1 0.6 5.9 0.0 0.0 0.5 0.3 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.6 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 2.7 4.1 4.6 3.6 7.8 4.0 5.3 3.1 2.1 5.1 1.6 0.1 0.0 0.0 3.6 0.0 0.0 0.4 0.2 0.0 3.4 1.8 2.2 1.1 1.5 0.2 1.8 2.1 0.0 0.0 0.0 11.7 1.7 28.2 21.8 3.1 0.5 0.0 0.0 3.8 0.0 0.0 0.8 0.0 1.7 0.0 3.2 0.4 0.0 0.1 3.3 5.4 0.0 0.0 0.0 0.0 19.6 0.9 0.1 1.8 2.8 0.0 8.1 0.0 4.0 1.8 0.3 0.0 0.0 0.0 0.9 0.0 0.2 4.3 2.6 0.0 0.0 0.6 13.7 2.7 0.0 0.0 0.0 0.1 6.7 0.0 0.5